Search of human proteins with 189458898

Search of human proteins with 189458898

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens]
         (770 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens]      1539   0.0  
gi|4505911 postmeiotic segregation 1 isoform a [Homo sapiens]        1230   0.0  
gi|189458896 postmeiotic segregation 1 isoform b [Homo sapiens]      1134   0.0  
gi|4505913 PMS2 postmeiotic segregation increased 2 isoform a [H...   183   6e-46
gi|4557757 MutL protein homolog 1 [Homo sapiens]                      131   3e-30
gi|239743246 PREDICTED: hypothetical protein XP_002342778 [Homo ...   125   2e-28
gi|169170512 PREDICTED: similar to Postmeiotic segregation incre...   125   2e-28
gi|91992162 mutL homolog 3 isoform 1 [Homo sapiens]                   103   8e-22
gi|91992160 mutL homolog 3 isoform 2 [Homo sapiens]                   103   8e-22
gi|4507225 sex determining region Y [Homo sapiens]                     46   1e-04
gi|169184027 PREDICTED: similar to high mobility group box 3 [Ho...    39   0.014
gi|113421073 PREDICTED: similar to high mobility group box 3 [Ho...    39   0.014
gi|113420668 PREDICTED: similar to high mobility group box 3 [Ho...    39   0.014
gi|194688135 high-mobility group box 2 [Homo sapiens]                  39   0.018
gi|194688133 high-mobility group box 2 [Homo sapiens]                  39   0.018
gi|11321591 high-mobility group box 2 [Homo sapiens]                   39   0.018
gi|4507241 structure specific recognition protein 1 [Homo sapiens]     39   0.024
gi|71143137 high-mobility group box 3 [Homo sapiens]                   39   0.024
gi|169168462 PREDICTED: similar to high mobility group box 3 [Ho...    38   0.041
gi|169168166 PREDICTED: similar to high mobility group box 3 [Ho...    38   0.041
gi|239742753 PREDICTED: similar to high mobility group box 3 iso...    38   0.041
gi|113416897 PREDICTED: similar to high mobility group box 3 iso...    38   0.041
gi|28195386 sex-determining region Y-box 2 [Homo sapiens]              37   0.053
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo...    37   0.053
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom...    37   0.053
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]        37   0.069
gi|149408146 TOX high mobility group box family member 2 isoform...    37   0.090
gi|149408144 TOX high mobility group box family member 2 isoform...    37   0.090
gi|149408141 TOX high mobility group box family member 2 isoform...    37   0.090
gi|14249636 TOX high mobility group box family member 2 isoform ...    37   0.090

>gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens]
          Length = 770

 Score = 1539 bits (3985), Expect = 0.0
 Identities = 770/770 (100%), Positives = 770/770 (100%)

Query: 1   MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60
           MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
Sbjct: 1   MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60

Query: 61  IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120
           IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
Sbjct: 61  IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120

Query: 121 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG 180
           YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
Sbjct: 121 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG 180

Query: 181 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL 240
           ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
Sbjct: 181 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL 240

Query: 241 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID 300
           PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
Sbjct: 241 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID 300

Query: 301 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL 360
           VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
Sbjct: 301 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL 360

Query: 361 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH 420
           SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
Sbjct: 361 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH 420

Query: 421 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE 480
           CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
Sbjct: 421 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE 480

Query: 481 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN 540
           NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
Sbjct: 481 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN 540

Query: 541 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED 600
           LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
Sbjct: 541 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED 600

Query: 601 ATLQIEELWKTLSEEEKLNLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKL 660
           ATLQIEELWKTLSEEEKLNLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKL
Sbjct: 601 ATLQIEELWKTLSEEEKLNLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKL 660

Query: 661 IPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAV 720
           IPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAV
Sbjct: 661 IPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAV 720

Query: 721 RLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLTYLPETT 770
           RLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
Sbjct: 721 RLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLTYLPETT 770


>gi|4505911 postmeiotic segregation 1 isoform a [Homo sapiens]
          Length = 932

 Score = 1230 bits (3182), Expect = 0.0
 Identities = 623/641 (97%), Positives = 625/641 (97%), Gaps = 9/641 (1%)

Query: 1   MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60
           MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
Sbjct: 1   MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60

Query: 61  IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120
           IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
Sbjct: 61  IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120

Query: 121 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG 180
           YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
Sbjct: 121 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG 180

Query: 181 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL 240
           ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
Sbjct: 181 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL 240

Query: 241 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID 300
           PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
Sbjct: 241 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID 300

Query: 301 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL 360
           VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
Sbjct: 301 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL 360

Query: 361 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH 420
           SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
Sbjct: 361 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH 420

Query: 421 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE 480
           CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
Sbjct: 421 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE 480

Query: 481 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN 540
           NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
Sbjct: 481 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN 540

Query: 541 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED 600
           LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
Sbjct: 541 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED 600

Query: 601 ATLQIEELWKTLSEEEKLNLFNGSHYLDVLYKMTADDQRYS 641
           ATLQIEELWKTLSEEEKL             K T D +RY+
Sbjct: 601 ATLQIEELWKTLSEEEKLKYEE---------KATKDLERYN 632



 Score =  315 bits (808), Expect = 8e-86
 Identities = 159/176 (90%), Positives = 162/176 (92%), Gaps = 2/176 (1%)

Query: 595 KTSLEDATLQIEELWKTLSEEEKLNLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTAN 654
           K  LE+  L  E L K +   E  +LFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTAN
Sbjct: 759 KRLLENHKLPAEPLEKPIMLTE--SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTAN 816

Query: 655 GFKIKLIPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVYECRPRKVISY 714
           GFKIKLIPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVYECRPRKVISY
Sbjct: 817 GFKIKLIPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVYECRPRKVISY 876

Query: 715 LEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLTYLPETT 770
           LEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
Sbjct: 877 LEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLTYLPETT 932


>gi|189458896 postmeiotic segregation 1 isoform b [Homo sapiens]
          Length = 893

 Score = 1134 bits (2934), Expect = 0.0
 Identities = 584/641 (91%), Positives = 586/641 (91%), Gaps = 48/641 (7%)

Query: 1   MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60
           MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
Sbjct: 1   MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60

Query: 61  IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120
           IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
Sbjct: 61  IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120

Query: 121 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG 180
           YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
Sbjct: 121 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG 180

Query: 181 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL 240
           ILKPDLRIVFVHNK                                       IYLSGFL
Sbjct: 181 ILKPDLRIVFVHNK---------------------------------------IYLSGFL 201

Query: 241 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID 300
           PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
Sbjct: 202 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID 261

Query: 301 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL 360
           VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
Sbjct: 262 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL 321

Query: 361 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH 420
           SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
Sbjct: 322 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH 381

Query: 421 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE 480
           CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
Sbjct: 382 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE 441

Query: 481 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN 540
           NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
Sbjct: 442 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN 501

Query: 541 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED 600
           LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
Sbjct: 502 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED 561

Query: 601 ATLQIEELWKTLSEEEKLNLFNGSHYLDVLYKMTADDQRYS 641
           ATLQIEELWKTLSEEEKL             K T D +RY+
Sbjct: 562 ATLQIEELWKTLSEEEKLKYEE---------KATKDLERYN 593



 Score =  315 bits (808), Expect = 8e-86
 Identities = 159/176 (90%), Positives = 162/176 (92%), Gaps = 2/176 (1%)

Query: 595 KTSLEDATLQIEELWKTLSEEEKLNLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTAN 654
           K  LE+  L  E L K +   E  +LFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTAN
Sbjct: 720 KRLLENHKLPAEPLEKPIMLTE--SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTAN 777

Query: 655 GFKIKLIPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVYECRPRKVISY 714
           GFKIKLIPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVYECRPRKVISY
Sbjct: 778 GFKIKLIPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVYECRPRKVISY 837

Query: 715 LEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLTYLPETT 770
           LEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
Sbjct: 838 LEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLTYLPETT 893


>gi|4505913 PMS2 postmeiotic segregation increased 2 isoform a [Homo
           sapiens]
          Length = 862

 Score =  183 bits (464), Expect = 6e-46
 Identities = 211/870 (24%), Positives = 358/870 (41%), Gaps = 132/870 (15%)

Query: 1   MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60
           +K +   +V  + S Q++ S+ + VKEL+ENSLDAGAT++D+KL++YG D IEV DNG G
Sbjct: 15  IKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKDYGVDLIEVSDNGCG 74

Query: 61  IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120
           ++  +   + +K++TSKI    DL  + T+GFRGEAL S+C +++V I+T  A+    T+
Sbjct: 75  VEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHASAKVGTR 134

Query: 121 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVR-KQFYSTAKKCKDEIKKIQDLLMSF 179
            + D +G I+ + P    +GTTV+  +LF  LPVR K+F    KK   E  K+  +L ++
Sbjct: 135 LMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKK---EYAKMVQVLHAY 191

Query: 180 GILKPDLRIVFVH-----NKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQI 234
            I+   +R+   +      +  +         K  + SV G   + ++  F        +
Sbjct: 192 CIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSV 251

Query: 235 ----------------YLSGFLPKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRH 278
                           Y+SGF+ +C   H     ST +R F FIN RP     + +L+  
Sbjct: 252 CEEYGLSCSDALHNLFYISGFISQC--THGVGRSST-DRQFFFINRRPCDPAKVCRLVNE 308

Query: 279 HYNLKCLKESTRLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYG 338
            Y++     +   YP   L I V +  VD+N+TPDK Q+LLQ +E +L+A+  L T+  G
Sbjct: 309 VYHM----YNRHQYPFVVLNISVDSECVDINVTPDKRQILLQ-EEKLLLAV--LKTSLIG 361

Query: 339 PLPSTNSYENNKTDVSAADIV-----LSKTAETDVLFNKVESSGKNYS------NVDTSV 387
              S    + NK +VS   ++     L K    D+    VE   ++ S        D S+
Sbjct: 362 MFDS----DVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPSLRTGEEKKDVSI 417

Query: 388 IPFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSSEISNIDKNTKNAFQDISMSNVSWE 447
               + +    S ++T +   H     +        +   +  +T  A  D  +     E
Sbjct: 418 ----SRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDKGVLRPQKE 473

Query: 448 NSQTEYSKTCFISSVKHTQSENGNKDHIDESGENEEEAGLENSSEISA----DEWSRGNI 503
              + +  +      +  +        +D  G +  + G   SSE +A    D  S+ ++
Sbjct: 474 AVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPGDRGSQEHV 533

Query: 504 LKN----SVGENIEPVKILVPEKSLPCKV----SNNNYPIP-------EQMNLNEDSCNK 548
                     ++   V     ++   CK        N   P       E++  + D C K
Sbjct: 534 DSQEKAPETDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEILSSSDICQK 593

Query: 549 KSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQ----DHRPQ-------------FLI 591
             N  D  + +V     ++ +V+    S S+L  +     H  Q              + 
Sbjct: 594 LVNTQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNYRKFRAKIC 653

Query: 592 ENPKTSLEDATLQIEELWKTL-SEEEKLNLFNGSHYLDVLYK------MTADDQRYS--- 641
                + ED     +E+ KT+ +E E +  FN    +  L +        A D++Y+   
Sbjct: 654 PGENQAAEDELR--KEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDEKYNFEM 711

Query: 642 --GSTYLSDPRLTA-----------------------NGFKIKLIPGVSITENYLEIEGM 676
               T L   RL A                       NGF   +     +TE    I   
Sbjct: 712 LQQHTVLQGQRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERAKLISLP 771

Query: 677 ANCLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQ 736
            +    +G  D+ E++  + +        CRP +V       A R S  +   L+  +++
Sbjct: 772 TSKNWTFGPQDVDELIFMLSDSPG---VMCRPSRVKQMFASRACRKSVMIGTALNTSEMK 828

Query: 737 DIIYRMKHQFGNEIKECVHGRPFFHHLTYL 766
            +I  M     +    C HGRP   H+  L
Sbjct: 829 KLITHMGEM--DHPWNCPHGRPTMRHIANL 856


>gi|4557757 MutL protein homolog 1 [Homo sapiens]
          Length = 756

 Score =  131 bits (329), Expect = 3e-30
 Identities = 92/332 (27%), Positives = 162/332 (48%), Gaps = 22/332 (6%)

Query: 1   MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60
           +++L    V  +++ ++I    + +KE+IEN LDA +TS+ V ++  G   I+++DNG G
Sbjct: 8   IRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGTG 67

Query: 61  IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120
           I+  D  ++  ++ TSK+ S EDL +++TYGFRGEAL SI  +A V ITT+TA    + +
Sbjct: 68  IRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYR 127

Query: 121 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG 180
                       KP    QGT +T   LF N+  R++     K   +E  KI +++  + 
Sbjct: 128 ASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRK---ALKNPSEEYGKILEVVGRYS 184

Query: 181 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL 240
                     VHN  + +   +  +    + ++   + ++N+ S   ++   ++   G  
Sbjct: 185 ----------VHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCE 234

Query: 241 PKCDADHSFTSLSTPERS------FIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPV 294
            K  A      +S    S       +FIN R V    + K I   Y     K +   +P 
Sbjct: 235 DKTLAFKMNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNT---HPF 291

Query: 295 FFLKIDVPTADVDVNLTPDKSQVLLQNKESVL 326
            +L +++   +VDVN+ P K +V   ++ES+L
Sbjct: 292 LYLSLEISPQNVDVNVHPTKHEVHFLHEESIL 323


>gi|239743246 PREDICTED: hypothetical protein XP_002342778 [Homo
           sapiens]
          Length = 255

 Score =  125 bits (313), Expect = 2e-28
 Identities = 64/165 (38%), Positives = 104/165 (63%), Gaps = 1/165 (0%)

Query: 1   MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60
           +K +   +V  + S  ++ S+ + VK+++ NSLDAGAT++D+KL++YG D IEV  NG G
Sbjct: 30  IKPIDRKSVHQICSGPVVLSLSTAVKKIVGNSLDAGATNIDLKLKDYGMDLIEVSGNGCG 89

Query: 61  IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120
           ++  +   + +K++TSKI    DL  + T+GF+G+AL S+C +++V I+T   +    T+
Sbjct: 90  VEEENFEGLTLKHHTSKIREFADLTRVETFGFQGKALSSLCALSDVTISTCHVSAKVGTR 149

Query: 121 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVR-KQFYSTAKK 164
            V D  G I+ + P    +GTTV+  +LF  LPVR K+F    KK
Sbjct: 150 LVFDHDGKIIQKTPYPHPRGTTVSVKQLFSTLPVRHKEFQRNIKK 194


>gi|169170512 PREDICTED: similar to Postmeiotic segregation
           increased 4-like protein [Homo sapiens]
          Length = 255

 Score =  125 bits (313), Expect = 2e-28
 Identities = 64/165 (38%), Positives = 104/165 (63%), Gaps = 1/165 (0%)

Query: 1   MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60
           +K +   +V  + S  ++ S+ + VK+++ NSLDAGAT++D+KL++YG D IEV  NG G
Sbjct: 30  IKPIDRKSVHQICSGPVVLSLSTAVKKIVGNSLDAGATNIDLKLKDYGMDLIEVSGNGCG 89

Query: 61  IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120
           ++  +   + +K++TSKI    DL  + T+GF+G+AL S+C +++V I+T   +    T+
Sbjct: 90  VEEENFEGLTLKHHTSKIREFADLTRVETFGFQGKALSSLCALSDVTISTCHVSAKVGTR 149

Query: 121 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVR-KQFYSTAKK 164
            V D  G I+ + P    +GTTV+  +LF  LPVR K+F    KK
Sbjct: 150 LVFDHDGKIIQKTPYPHPRGTTVSVKQLFSTLPVRHKEFQRNIKK 194


>gi|91992162 mutL homolog 3 isoform 1 [Homo sapiens]
          Length = 1453

 Score =  103 bits (256), Expect = 8e-22
 Identities = 133/567 (23%), Positives = 223/567 (39%), Gaps = 97/567 (17%)

Query: 12  LSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEGIKAVDAPVMAM 71
           L S   I+S+   V+EL  NS+DA A  V V++    F +++V DNG G+ + D   +  
Sbjct: 13  LRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETF-QVQVIDNGFGMGSDDVEKVGN 71

Query: 72  KYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQYVLDGSGHIL- 130
           +Y+TSK +S +DLEN   YGFRGEAL +I  +A  +  +        T   L  SG  L 
Sbjct: 72  RYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTFVKLFQSGKALK 131

Query: 131 --SQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKD---EIKKIQDLLMSFGILKPD 185
                 +    GTTVT   LF  LPVR       +KC D   E +K++  + +  ++ P 
Sbjct: 132 ACEADVTRASAGTTVTVYNLFYQLPVR-------RKCMDPRLEFEKVRQRIEALSLMHPS 184

Query: 186 LRIVFVH--NKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKC 243
           +     +  + +++ Q  +  D       + G      +    +  +E +  LSG++   
Sbjct: 185 ISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFE--LSGYI--- 239

Query: 244 DADHSFTSLSTPERSFIFINSRPVHQKDILKLI------------------RHHYNLKCL 285
               S  +       F+F+N R V +  + KLI                      N    
Sbjct: 240 ----SSEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLR 295

Query: 286 KEST-RLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVLIAL----------ENLMT 334
             ST  LY ++ + +     + DV + P K+ +  QN +++L  +          E L  
Sbjct: 296 HRSTPELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFV 355

Query: 335 TCYGPLPSTNSYENNKTDVSAADIVLSKTAETD----------------VLFNKVESSGK 378
              G      S +N     S  D  L K   +D                 +FN    + K
Sbjct: 356 ELSGEDIKEFSEDNG---FSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVK 412

Query: 379 NYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSS-EISNIDKNTKNAFQ 437
             +  +   +  Q+   ++ + KNT+D   +    G  G+   +   + N D +   +  
Sbjct: 413 RKTTAEN--VNTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKM 470

Query: 438 DISMSNVSWENSQTEYSKTCFISSVKHTQSEN-------------GNKDHIDESGENEEE 484
               + V+ E  + E  K  F+   +H+  EN                 H +ESG++   
Sbjct: 471 LEQETIVASEAGENEKHKKSFL---EHSSLENPCGTSLEMFLSPFQTPCHFEESGQD--- 524

Query: 485 AGLENSSEISADEWSRGNILKNSVGEN 511
             LE   E +       NILKN+  +N
Sbjct: 525 --LEIWKESTTVNGMAANILKNNRIQN 549


>gi|91992160 mutL homolog 3 isoform 2 [Homo sapiens]
          Length = 1429

 Score =  103 bits (256), Expect = 8e-22
 Identities = 133/567 (23%), Positives = 223/567 (39%), Gaps = 97/567 (17%)

Query: 12  LSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEGIKAVDAPVMAM 71
           L S   I+S+   V+EL  NS+DA A  V V++    F +++V DNG G+ + D   +  
Sbjct: 13  LRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETF-QVQVIDNGFGMGSDDVEKVGN 71

Query: 72  KYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQYVLDGSGHIL- 130
           +Y+TSK +S +DLEN   YGFRGEAL +I  +A  +  +        T   L  SG  L 
Sbjct: 72  RYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTFVKLFQSGKALK 131

Query: 131 --SQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKD---EIKKIQDLLMSFGILKPD 185
                 +    GTTVT   LF  LPVR       +KC D   E +K++  + +  ++ P 
Sbjct: 132 ACEADVTRASAGTTVTVYNLFYQLPVR-------RKCMDPRLEFEKVRQRIEALSLMHPS 184

Query: 186 LRIVFVH--NKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKC 243
           +     +  + +++ Q  +  D       + G      +    +  +E +  LSG++   
Sbjct: 185 ISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFE--LSGYI--- 239

Query: 244 DADHSFTSLSTPERSFIFINSRPVHQKDILKLI------------------RHHYNLKCL 285
               S  +       F+F+N R V +  + KLI                      N    
Sbjct: 240 ----SSEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLR 295

Query: 286 KEST-RLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVLIAL----------ENLMT 334
             ST  LY ++ + +     + DV + P K+ +  QN +++L  +          E L  
Sbjct: 296 HRSTPELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFV 355

Query: 335 TCYGPLPSTNSYENNKTDVSAADIVLSKTAETD----------------VLFNKVESSGK 378
              G      S +N     S  D  L K   +D                 +FN    + K
Sbjct: 356 ELSGEDIKEFSEDNG---FSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVK 412

Query: 379 NYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSS-EISNIDKNTKNAFQ 437
             +  +   +  Q+   ++ + KNT+D   +    G  G+   +   + N D +   +  
Sbjct: 413 RKTTAEN--VNTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKM 470

Query: 438 DISMSNVSWENSQTEYSKTCFISSVKHTQSEN-------------GNKDHIDESGENEEE 484
               + V+ E  + E  K  F+   +H+  EN                 H +ESG++   
Sbjct: 471 LEQETIVASEAGENEKHKKSFL---EHSSLENPCGTSLEMFLSPFQTPCHFEESGQD--- 524

Query: 485 AGLENSSEISADEWSRGNILKNSVGEN 511
             LE   E +       NILKN+  +N
Sbjct: 525 --LEIWKESTTVNGMAANILKNNRIQN 549


>gi|4507225 sex determining region Y [Homo sapiens]
          Length = 204

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 25/97 (25%), Positives = 47/97 (48%), Gaps = 5/97 (5%)

Query: 544 DSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLEDATL 603
           +SCN K      ++ K    D      +K+PM+A  ++ +D R +  +ENP+    + + 
Sbjct: 38  ESCNSKYQCETGENSKGNVQDR-----VKRPMNAFIVWSRDQRRKMALENPRMRNSEISK 92

Query: 604 QIEELWKTLSEEEKLNLFNGSHYLDVLYKMTADDQRY 640
           Q+   WK L+E EK   F  +  L  +++    + +Y
Sbjct: 93  QLGYQWKMLTEAEKWPFFQEAQKLQAMHREKYPNYKY 129


>gi|169184027 PREDICTED: similar to high mobility group box 3 [Homo
           sapiens]
          Length = 208

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 21/74 (28%), Positives = 33/74 (44%)

Query: 572 KKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLNLFNGSHYLDVLY 631
           K+P S   LF  + RP+    NP  S+ D   ++ E+W  L++ EK      +  L   Y
Sbjct: 93  KRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYVTKAAKLKEKY 152

Query: 632 KMTADDQRYSGSTY 645
           +    D +  G  Y
Sbjct: 153 EKDVVDCKLKGKFY 166


>gi|113421073 PREDICTED: similar to high mobility group box 3 [Homo
           sapiens]
          Length = 208

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 21/74 (28%), Positives = 33/74 (44%)

Query: 572 KKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLNLFNGSHYLDVLY 631
           K+P S   LF  + RP+    NP  S+ D   ++ E+W  L++ EK      +  L   Y
Sbjct: 93  KRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYVTKAAKLKEKY 152

Query: 632 KMTADDQRYSGSTY 645
           +    D +  G  Y
Sbjct: 153 EKDVVDCKLKGKFY 166


>gi|113420668 PREDICTED: similar to high mobility group box 3 [Homo
           sapiens]
          Length = 208

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 21/74 (28%), Positives = 33/74 (44%)

Query: 572 KKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLNLFNGSHYLDVLY 631
           K+P S   LF  + RP+    NP  S+ D   ++ E+W  L++ EK      +  L   Y
Sbjct: 93  KRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYVTKAAKLKEKY 152

Query: 632 KMTADDQRYSGSTY 645
           +    D +  G  Y
Sbjct: 153 EKDVVDCKLKGKFY 166


>gi|194688135 high-mobility group box 2 [Homo sapiens]
          Length = 209

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 17/46 (36%), Positives = 27/46 (58%)

Query: 572 KKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEK 617
           K+P SA  LF  +HRP+   E+P  S+ D   ++ E+W   S ++K
Sbjct: 96  KRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDK 141


>gi|194688133 high-mobility group box 2 [Homo sapiens]
          Length = 209

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 17/46 (36%), Positives = 27/46 (58%)

Query: 572 KKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEK 617
           K+P SA  LF  +HRP+   E+P  S+ D   ++ E+W   S ++K
Sbjct: 96  KRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDK 141


>gi|11321591 high-mobility group box 2 [Homo sapiens]
          Length = 209

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 17/46 (36%), Positives = 27/46 (58%)

Query: 572 KKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEK 617
           K+P SA  LF  +HRP+   E+P  S+ D   ++ E+W   S ++K
Sbjct: 96  KRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDK 141


>gi|4507241 structure specific recognition protein 1 [Homo sapiens]
          Length = 709

 Score = 38.5 bits (88), Expect = 0.024
 Identities = 51/226 (22%), Positives = 89/226 (39%), Gaps = 23/226 (10%)

Query: 410 QISIGDFGYGHCSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTC-FISSVKHTQSE 468
           +IS  +F  G  ++   + +  TK   Q  + S++  E    EY K   F+++ K     
Sbjct: 373 EISFVNFARGTTTTRSFDFEIETKQGTQ-YTFSSIERE----EYGKLFDFVNAKKLNIKN 427

Query: 469 NGNK-------DHIDESGENEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPE 521
            G K       D   +S E++ +A LE   E         N   +  GE  +       E
Sbjct: 428 RGLKEGMNPSYDEYADSDEDQHDAYLERMKEEGKIREENANDSSDDSGEETDESFNPGEE 487

Query: 522 KSLPCKVSNNNYPIPEQMNLNEDSCNKKSN--------VIDNKSGK--VTAYDLLSNRVI 571
           +    +  ++N       N  +   ++K            D KS K  V           
Sbjct: 488 EEDVAEEFDSNASASSSSNEGDSDRDEKKRKQLKKAKMAKDRKSRKKPVEVKKGKDPNAP 547

Query: 572 KKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEK 617
           K+PMSA  L++   R +   ++P  S+ D + +  E+WK +S+E+K
Sbjct: 548 KRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKK 593


>gi|71143137 high-mobility group box 3 [Homo sapiens]
          Length = 200

 Score = 38.5 bits (88), Expect = 0.024
 Identities = 20/71 (28%), Positives = 32/71 (45%)

Query: 572 KKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLNLFNGSHYLDVLY 631
           K+P S   LF  + RP+    NP  S+ D   ++ E+W  L++ EK      +  L   Y
Sbjct: 94  KRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKY 153

Query: 632 KMTADDQRYSG 642
           +    D +  G
Sbjct: 154 EKDVADYKSKG 164



 Score = 31.6 bits (70), Expect = 2.9
 Identities = 21/51 (41%), Positives = 29/51 (56%), Gaps = 5/51 (9%)

Query: 572 KKP---MSASALFVQDHRPQFLIENPKTSLEDA--TLQIEELWKTLSEEEK 617
           KKP   MSA A FVQ  R +   +NP+  +  A  + +  E WKT+S +EK
Sbjct: 7   KKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEK 57


>gi|169168462 PREDICTED: similar to high mobility group box 3 [Homo
           sapiens]
          Length = 204

 Score = 37.7 bits (86), Expect = 0.041
 Identities = 20/71 (28%), Positives = 32/71 (45%)

Query: 572 KKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLNLFNGSHYLDVLY 631
           K+P S   LF  + RP+    NP  S+ D   ++ E+W  L++ EK      +  L   Y
Sbjct: 89  KRPPSGFFLFSSEIRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYITKTAKLKEKY 148

Query: 632 KMTADDQRYSG 642
           +    D +  G
Sbjct: 149 EKDVADSKSKG 159


>gi|169168166 PREDICTED: similar to high mobility group box 3 [Homo
           sapiens]
          Length = 204

 Score = 37.7 bits (86), Expect = 0.041
 Identities = 20/71 (28%), Positives = 32/71 (45%)

Query: 572 KKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLNLFNGSHYLDVLY 631
           K+P S   LF  + RP+    NP  S+ D   ++ E+W  L++ EK      +  L   Y
Sbjct: 89  KRPPSGFFLFSSEIRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYITKTAKLKEKY 148

Query: 632 KMTADDQRYSG 642
           +    D +  G
Sbjct: 149 EKDVADSKSKG 159


>gi|239742753 PREDICTED: similar to high mobility group box 3
           isoform 2 [Homo sapiens]
          Length = 183

 Score = 37.7 bits (86), Expect = 0.041
 Identities = 20/71 (28%), Positives = 32/71 (45%)

Query: 572 KKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLNLFNGSHYLDVLY 631
           K+P S   LF  + RP+    NP  S+ D   ++ E+W  L++ EK      +  L   Y
Sbjct: 71  KRPPSGFFLFSSEIRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYITKTAKLKEKY 130

Query: 632 KMTADDQRYSG 642
           +    D +  G
Sbjct: 131 EKDVADSKSKG 141


>gi|113416897 PREDICTED: similar to high mobility group box 3
           isoform 1 [Homo sapiens]
          Length = 201

 Score = 37.7 bits (86), Expect = 0.041
 Identities = 20/71 (28%), Positives = 32/71 (45%)

Query: 572 KKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLNLFNGSHYLDVLY 631
           K+P S   LF  + RP+    NP  S+ D   ++ E+W  L++ EK      +  L   Y
Sbjct: 89  KRPPSGFFLFSSEIRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYITKTAKLKEKY 148

Query: 632 KMTADDQRYSG 642
           +    D +  G
Sbjct: 149 EKDVADSKSKG 159


>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
          Length = 317

 Score = 37.4 bits (85), Expect = 0.053
 Identities = 20/70 (28%), Positives = 35/70 (50%)

Query: 571 IKKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLNLFNGSHYLDVL 630
           +K+PM+A  ++ +  R +   ENPK    + + ++   WK LSE EK    + +  L  L
Sbjct: 41  VKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRAL 100

Query: 631 YKMTADDQRY 640
           +     D +Y
Sbjct: 101 HMKEHPDYKY 110


>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
           sapiens]
          Length = 501

 Score = 37.4 bits (85), Expect = 0.053
 Identities = 17/50 (34%), Positives = 29/50 (58%)

Query: 568 NRVIKKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEK 617
           N  +K+PM+A  ++ + HRP     NP  +  + ++Q+   W  LSEE+K
Sbjct: 334 NGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQK 383


>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
           sapiens]
          Length = 753

 Score = 37.4 bits (85), Expect = 0.053
 Identities = 17/50 (34%), Positives = 29/50 (58%)

Query: 568 NRVIKKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEK 617
           N  +K+PM+A  ++ + HRP     NP  +  + ++Q+   W  LSEE+K
Sbjct: 334 NGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQK 383


>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
          Length = 391

 Score = 37.0 bits (84), Expect = 0.069
 Identities = 19/70 (27%), Positives = 35/70 (50%)

Query: 571 IKKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLNLFNGSHYLDVL 630
           +K+PM+A  ++ +  R +   ENPK    + + ++   WK +SE EK    + +  L  L
Sbjct: 51  VKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRAL 110

Query: 631 YKMTADDQRY 640
           +     D +Y
Sbjct: 111 HMKEHPDYKY 120


>gi|149408146 TOX high mobility group box family member 2 isoform b
           [Homo sapiens]
          Length = 488

 Score = 36.6 bits (83), Expect = 0.090
 Identities = 16/46 (34%), Positives = 27/46 (58%)

Query: 572 KKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEK 617
           +KP+SA ALF +D +     +NP  +  D +  +  +W +L EE+K
Sbjct: 256 QKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQK 301


>gi|149408144 TOX high mobility group box family member 2 isoform a
           [Homo sapiens]
          Length = 506

 Score = 36.6 bits (83), Expect = 0.090
 Identities = 16/46 (34%), Positives = 27/46 (58%)

Query: 572 KKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEK 617
           +KP+SA ALF +D +     +NP  +  D +  +  +W +L EE+K
Sbjct: 247 QKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQK 292


>gi|149408141 TOX high mobility group box family member 2 isoform c
           [Homo sapiens]
          Length = 464

 Score = 36.6 bits (83), Expect = 0.090
 Identities = 16/46 (34%), Positives = 27/46 (58%)

Query: 572 KKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEK 617
           +KP+SA ALF +D +     +NP  +  D +  +  +W +L EE+K
Sbjct: 205 QKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQK 250


>gi|14249636 TOX high mobility group box family member 2 isoform c
           [Homo sapiens]
          Length = 464

 Score = 36.6 bits (83), Expect = 0.090
 Identities = 16/46 (34%), Positives = 27/46 (58%)

Query: 572 KKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEK 617
           +KP+SA ALF +D +     +NP  +  D +  +  +W +L EE+K
Sbjct: 205 QKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQK 250


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,460,026
Number of Sequences: 37866
Number of extensions: 1195169
Number of successful extensions: 2843
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 2708
Number of HSP's gapped (non-prelim): 155
length of query: 770
length of database: 18,247,518
effective HSP length: 110
effective length of query: 660
effective length of database: 14,082,258
effective search space: 9294290280
effective search space used: 9294290280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.