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Search of human proteins with 18765715
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18765715 major histocompatibility complex, class II, DM
alpha precursor [Homo sapiens]
(261 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18765715 major histocompatibility complex, class II, DM alpha... 552 e-157
gi|4504401 major histocompatibility complex, class II, DO alpha ... 102 3e-22
gi|113430811 PREDICTED: similar to major histocompatibility comp... 101 7e-22
gi|239740916 PREDICTED: similar to MHC HLA-DQ alpha [Homo sapiens] 101 7e-22
gi|239740798 PREDICTED: similar to MHC class II antigen [Homo sa... 101 7e-22
gi|11095447 major histocompatibility complex, class II, DQ alpha... 100 2e-21
gi|169217612 PREDICTED: similar to major histocompatibility comp... 100 2e-21
gi|239740747 PREDICTED: similar to major histocompatibility comp... 100 2e-21
gi|239740697 PREDICTED: similar to major histocompatibility comp... 100 2e-21
gi|18426975 major histocompatibility complex, class II, DQ alpha... 100 2e-21
gi|24797074 major histocompatibility complex, class II, DP alpha... 97 1e-20
gi|52426774 major histocompatibility complex, class II, DR alpha... 94 1e-19
gi|239740861 PREDICTED: similar to major histocompatibility comp... 90 2e-18
gi|239513953 PREDICTED: similar to major histocompatibility comp... 90 2e-18
gi|169218140 PREDICTED: similar to major histocompatibility comp... 84 2e-16
gi|4504399 major histocompatibility complex, class II, DM beta p... 49 6e-06
gi|239752152 PREDICTED: hypothetical protein XP_002348153 [Homo ... 47 2e-05
gi|4757826 beta-2-microglobulin precursor [Homo sapiens] 45 8e-05
gi|239740920 PREDICTED: similar to major histocompatibility comp... 44 1e-04
gi|239740918 PREDICTED: similar to major histocompatibility comp... 44 1e-04
gi|13399298 immunoglobulin lambda-like polypeptide 1 isoform a p... 44 1e-04
gi|169168591 PREDICTED: similar to major histocompatibility comp... 42 5e-04
gi|239748788 PREDICTED: similar to major histocompatibility comp... 42 5e-04
gi|239740863 PREDICTED: similar to major histocompatibility comp... 42 5e-04
gi|239513955 PREDICTED: similar to major histocompatibility comp... 42 5e-04
gi|239758095 PREDICTED: similar to major histocompatibility comp... 42 7e-04
gi|239740749 PREDICTED: similar to major histocompatibility comp... 42 7e-04
gi|17986005 major histocompatibility complex, class II, DR beta ... 41 0.001
gi|239740855 PREDICTED: similar to major histocompatibility comp... 41 0.001
gi|239740853 PREDICTED: similar to major histocompatibility comp... 41 0.001
>gi|18765715 major histocompatibility complex, class II, DM alpha
precursor [Homo sapiens]
Length = 261
Score = 552 bits (1422), Expect = e-157
Identities = 261/261 (100%), Positives = 261/261 (100%)
Query: 1 MGHEQNQGAALLQMLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLS 60
MGHEQNQGAALLQMLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLS
Sbjct: 1 MGHEQNQGAALLQMLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLS 60
Query: 61 EAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQQIGPKLDGKI 120
EAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQQIGPKLDGKI
Sbjct: 61 EAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQQIGPKLDGKI 120
Query: 121 PVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPVEGFGPTFVSAVD 180
PVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPVEGFGPTFVSAVD
Sbjct: 121 PVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPVEGFGPTFVSAVD 180
Query: 181 GLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLG 240
GLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLG
Sbjct: 181 GLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLG 240
Query: 241 VLGIIVGIVLIIYFRKPCSGD 261
VLGIIVGIVLIIYFRKPCSGD
Sbjct: 241 VLGIIVGIVLIIYFRKPCSGD 261
>gi|4504401 major histocompatibility complex, class II, DO alpha
precursor [Homo sapiens]
Length = 250
Score = 102 bits (254), Expect = 3e-22
Identities = 66/209 (31%), Positives = 103/209 (49%), Gaps = 11/209 (5%)
Query: 49 YCQDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQ--EQGDAPAILFDKEFCE 106
+ Q S + +DE+QLF D ++ V RLPEF D+A+ QG I K +
Sbjct: 38 FYQSYGASGQFTHEFDEEQLFSVDLKKSEAVWRLPEFGDFARFDPQGGLAGIAAIKAHLD 97
Query: 107 WMIQQIGPKLDGKIPVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSV 166
++++ +P P V +E G+PN L+C V N+FPP++ + W +
Sbjct: 98 ILVERSNRSRAINVP-----PRVTVLPKSRVELGQPNILICIVDNIFPPVINITWLRNGQ 152
Query: 167 PV-EGFGPT-FVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNAL- 223
V EG T F S D L F+ F YL F P D++ C V H + +W + +
Sbjct: 153 TVTEGVAQTSFYSQPDHL-FRKFHYLPFVPSAEDVYDCQVEHWGLDAPLLRHWELQVPIP 211
Query: 224 PSDLLENVLCGVAFGLGVLGIIVGIVLII 252
P D +E ++C + +G++G +VG VLII
Sbjct: 212 PPDAMETLVCALGLAIGLVGFLVGTVLII 240
>gi|113430811 PREDICTED: similar to major histocompatibility
complex, class II, DQ alpha 1 [Homo sapiens]
Length = 255
Score = 101 bits (251), Expect = 7e-22
Identities = 69/211 (32%), Positives = 99/211 (46%), Gaps = 19/211 (9%)
Query: 51 QDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQ 110
Q PS S +D D+ F+ D + V +LP F + + FD +F I
Sbjct: 40 QSYGPSGQYSHEFDGDEEFYVDLERKETVWQLPLFRRFRR---------FDPQFALTNIA 90
Query: 111 QIGPKLDGKIPVSRG------FPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNW--Q 162
+ L+ I S P VF+ P+ G+PNTL+C V N+FPP++ + W
Sbjct: 91 VLKHNLNIVIKRSNSTAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSN 150
Query: 163 HHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNA 222
HSV EG T + SF SYL F P +I+ C V H + +W P
Sbjct: 151 GHSV-TEGVSETSFLSKSDHSFFKISYLTFLPSDDEIYDCKVEHWGLDEPLLKHWEPEIP 209
Query: 223 LP-SDLLENVLCGVAFGLGVLGIIVGIVLII 252
P S+L E V+C + +G++GI+VG VLII
Sbjct: 210 APMSELTETVVCALGLSVGLVGIVVGTVLII 240
>gi|239740916 PREDICTED: similar to MHC HLA-DQ alpha [Homo sapiens]
Length = 255
Score = 101 bits (251), Expect = 7e-22
Identities = 69/211 (32%), Positives = 99/211 (46%), Gaps = 19/211 (9%)
Query: 51 QDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQ 110
Q PS S +D D+ F+ D + V +LP F + + FD +F I
Sbjct: 40 QSYGPSGQYSHEFDGDEEFYVDLERKETVWQLPLFRRFRR---------FDPQFALTNIA 90
Query: 111 QIGPKLDGKIPVSRG------FPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNW--Q 162
+ L+ I S P VF+ P+ G+PNTL+C V N+FPP++ + W
Sbjct: 91 VLKHNLNIVIKRSNSTAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSN 150
Query: 163 HHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNA 222
HSV EG T + SF SYL F P +I+ C V H + +W P
Sbjct: 151 GHSV-TEGVSETSFLSKSDHSFFKISYLTFLPSADEIYDCKVEHWGLDEPLLKHWEPEIP 209
Query: 223 LP-SDLLENVLCGVAFGLGVLGIIVGIVLII 252
P S+L E V+C + +G++GI+VG VLII
Sbjct: 210 TPMSELTETVVCALGLSVGLVGIVVGTVLII 240
>gi|239740798 PREDICTED: similar to MHC class II antigen [Homo
sapiens]
Length = 255
Score = 101 bits (251), Expect = 7e-22
Identities = 69/211 (32%), Positives = 99/211 (46%), Gaps = 19/211 (9%)
Query: 51 QDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQ 110
Q PS S +D D+ F+ D + V +LP F + + FD +F I
Sbjct: 40 QSYGPSGQYSHEFDGDEEFYVDLERKETVWQLPLFRRFRR---------FDPQFALTNIA 90
Query: 111 QIGPKLDGKIPVSRG------FPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNW--Q 162
+ L+ I S P VF+ P+ G+PNTL+C V N+FPP++ + W
Sbjct: 91 VLKHNLNIVIKRSNSTAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSN 150
Query: 163 HHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNA 222
HSV EG T + SF SYL F P +I+ C V H + +W P
Sbjct: 151 GHSV-TEGVSETSFLSKSDHSFFKISYLTFLPSDDEIYDCKVEHWGLDEPLLKHWEPEIP 209
Query: 223 LP-SDLLENVLCGVAFGLGVLGIIVGIVLII 252
P S+L E V+C + +G++GI+VG VLII
Sbjct: 210 TPMSELTETVVCALGLSVGLVGIVVGTVLII 240
>gi|11095447 major histocompatibility complex, class II, DQ alpha 2
[Homo sapiens]
Length = 255
Score = 100 bits (248), Expect = 2e-21
Identities = 64/209 (30%), Positives = 98/209 (46%), Gaps = 11/209 (5%)
Query: 49 YCQDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQ--EQGDAPAILFDKEFCE 106
+ Q PS + +D D+ F+ D V +LP F+ + Q + K E
Sbjct: 38 FYQSHGPSGQYTHEFDGDEEFYVDLETKETVWQLPMFSKFISFDPQSALRNMAVGKHTLE 97
Query: 107 WMIQQIGPKLDGKIPVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNW--QHH 164
+M++Q + P VF+ P+ G+PNTL+C V N+FPP++ + W H
Sbjct: 98 FMMRQ-----SNSTAATNEVPEVTVFSKFPVTLGQPNTLICLVDNIFPPVVNITWLSNGH 152
Query: 165 SVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALP 224
SV EG T + SF SYL F P +I+ C V H + +W P P
Sbjct: 153 SV-TEGVSETSFLSKSDHSFFKISYLTFLPSADEIYDCKVEHWGLDEPLLKHWEPEIPAP 211
Query: 225 -SDLLENVLCGVAFGLGVLGIIVGIVLII 252
S+L E ++C + +G++GI+VG V II
Sbjct: 212 MSELTETLVCALGLSVGLMGIVVGTVFII 240
>gi|169217612 PREDICTED: similar to major histocompatibility
complex, class II, DQ alpha 1 isoform 1 [Homo sapiens]
Length = 254
Score = 100 bits (248), Expect = 2e-21
Identities = 68/211 (32%), Positives = 98/211 (46%), Gaps = 20/211 (9%)
Query: 51 QDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQ 110
Q PS + +D D+ F+ D + V +LP F + FD +F I
Sbjct: 40 QSYGPSGQFTHEFDGDEEFYVDLERKETVWKLPLFH----------RLRFDPQFALTNIA 89
Query: 111 QIGPKLDGKIPVSRG------FPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNW--Q 162
+ L+ I S P VF+ P+ G+PNTL+C V N+FPP++ + W
Sbjct: 90 VLKHNLNILIKRSNSTAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSN 149
Query: 163 HHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNA 222
HSV EG T + SF SYL F P +I+ C V H + +W P
Sbjct: 150 GHSV-TEGVSETSFLSKSDHSFFKISYLTFLPSADEIYDCKVEHWGLDEPLLKHWEPEIP 208
Query: 223 LP-SDLLENVLCGVAFGLGVLGIIVGIVLII 252
P S+L E V+C + +G++GI+VG VLII
Sbjct: 209 APMSELTETVVCALGLSVGLVGIVVGTVLII 239
>gi|239740747 PREDICTED: similar to major histocompatibility
complex, class II, DQ alpha 1 [Homo sapiens]
Length = 254
Score = 100 bits (248), Expect = 2e-21
Identities = 68/211 (32%), Positives = 98/211 (46%), Gaps = 20/211 (9%)
Query: 51 QDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQ 110
Q PS + +D D+ F+ D + V +LP F + FD +F I
Sbjct: 40 QSYGPSGQFTHEFDGDEEFYVDLERKETVWKLPLFH----------RLRFDPQFALTNIA 89
Query: 111 QIGPKLDGKIPVSRG------FPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNW--Q 162
+ L+ I S P VF+ P+ G+PNTL+C V N+FPP++ + W
Sbjct: 90 VLKHNLNILIKRSNSTAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSN 149
Query: 163 HHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNA 222
HSV EG T + SF SYL F P +I+ C V H + +W P
Sbjct: 150 GHSV-TEGVSETSFLSKSDHSFFKISYLTFLPSADEIYDCKVEHWGLDEPLLKHWEPEIP 208
Query: 223 LP-SDLLENVLCGVAFGLGVLGIIVGIVLII 252
P S+L E V+C + +G++GI+VG VLII
Sbjct: 209 APMSELTETVVCALGLSVGLVGIVVGTVLII 239
>gi|239740697 PREDICTED: similar to major histocompatibility
complex, class II, DQ alpha 1 [Homo sapiens]
Length = 254
Score = 100 bits (248), Expect = 2e-21
Identities = 68/211 (32%), Positives = 98/211 (46%), Gaps = 20/211 (9%)
Query: 51 QDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQ 110
Q PS + +D D+ F+ D + V +LP F + FD +F I
Sbjct: 40 QSYGPSGQFTHEFDGDEEFYVDLERKETVWKLPLFH----------RLRFDPQFALTNIA 89
Query: 111 QIGPKLDGKIPVSRG------FPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNW--Q 162
+ L+ I S P VF+ P+ G+PNTL+C V N+FPP++ + W
Sbjct: 90 VLKHNLNILIKRSNSTAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSN 149
Query: 163 HHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNA 222
HSV EG T + SF SYL F P +I+ C V H + +W P
Sbjct: 150 GHSV-TEGVSETSFLSKSDHSFFKISYLTFLPSADEIYDCKVEHWGLDEPLLKHWEPEIP 208
Query: 223 LP-SDLLENVLCGVAFGLGVLGIIVGIVLII 252
P S+L E V+C + +G++GI+VG VLII
Sbjct: 209 APMSELTETVVCALGLSVGLVGIVVGTVLII 239
>gi|18426975 major histocompatibility complex, class II, DQ alpha 1
precursor [Homo sapiens]
Length = 255
Score = 99.8 bits (247), Expect = 2e-21
Identities = 62/202 (30%), Positives = 94/202 (46%), Gaps = 9/202 (4%)
Query: 55 PSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWA--QEQGDAPAILFDKEFCEWMIQQI 112
PS + +D D+ F+ D + R PEF+ + QG + K MI++
Sbjct: 44 PSGQYTHEFDGDEQFYVDLERKETAWRWPEFSKFGGFDPQGALRNMAVAKHNLNIMIKRY 103
Query: 113 GPKLDGKIPVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPV-EGF 171
+ P VF+ P+ G+PNTL+C V N+FPP++ + W + V EG
Sbjct: 104 N-----STAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSNGQSVTEGV 158
Query: 172 GPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALP-SDLLEN 230
T + SF SYL F P +I+ C V H + +W P P S+L E
Sbjct: 159 SETSFLSKSDHSFFKISYLTFLPSADEIYDCKVEHWGLDQPLLKHWEPEIPAPMSELTET 218
Query: 231 VLCGVAFGLGVLGIIVGIVLII 252
V+C + +G++GI+VG V II
Sbjct: 219 VVCALGLSVGLMGIVVGTVFII 240
>gi|24797074 major histocompatibility complex, class II, DP alpha 1
precursor [Homo sapiens]
Length = 260
Score = 97.1 bits (240), Expect = 1e-20
Identities = 65/216 (30%), Positives = 95/216 (43%), Gaps = 9/216 (4%)
Query: 41 NHTFLHTVYCQDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEF--ADWAQEQGDAPAI 98
+H + + Q P+ +DED++F+ D + V L EF A + QG I
Sbjct: 35 DHVSTYAAFVQTHRPTGEFMFEFDEDEMFYVDLDKKETVWHLEEFGQAFSFEAQGGLANI 94
Query: 99 LFDKEFCEWMIQQIGPKLDGKIPVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLT 158
+IQ+ P P VF +P+E G+PNTL+C + FPP+L
Sbjct: 95 AILNNNLNTLIQRSNHTQATNDP-----PEVTVFPKEPVELGQPNTLICHIDKFFPPVLN 149
Query: 159 VNWQ-HHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYW 217
V W + + EG + SF F YL F P D + C V H + +W
Sbjct: 150 VTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHW 209
Query: 218 VPRNALP-SDLLENVLCGVAFGLGVLGIIVGIVLII 252
+ + + E VLC + LG++GIIVG VLII
Sbjct: 210 EAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLII 245
>gi|52426774 major histocompatibility complex, class II, DR alpha
precursor [Homo sapiens]
Length = 254
Score = 94.0 bits (232), Expect = 1e-19
Identities = 67/243 (27%), Positives = 104/243 (42%), Gaps = 20/243 (8%)
Query: 14 MLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLSEAYDEDQLFFFDF 73
++ +L SWA+ E H + + + S +D D++F D
Sbjct: 13 IIAVLMSAQESWAIKE-----------EHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDM 61
Query: 74 SQNTRVPRLPEFADWA--QEQGDAPAILFDKEFCEWMIQQIGPKLDGKIPVSRGFPIAEV 131
++ V RL EF +A + QG I DK E M K P++ P V
Sbjct: 62 AKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMT-----KRSNYTPITNVPPEVTV 116
Query: 132 FTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPV-EGFGPTFVSAVDGLSFQAFSYL 190
T P+E +PN L+CF+ PP++ V W + PV G T + F+ F YL
Sbjct: 117 LTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYL 176
Query: 191 NFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALP-SDLLENVLCGVAFGLGVLGIIVGIV 249
F P D++ C V H + +W P + ENV+C + +G++GII+G +
Sbjct: 177 PFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTI 236
Query: 250 LII 252
II
Sbjct: 237 FII 239
>gi|239740861 PREDICTED: similar to major histocompatibility
complex, class II, DQ alpha 1 [Homo sapiens]
Length = 254
Score = 90.1 bits (222), Expect = 2e-18
Identities = 63/211 (29%), Positives = 92/211 (43%), Gaps = 20/211 (9%)
Query: 51 QDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQ 110
Q PS + +D D+ F+ D + V LP + FD +F I
Sbjct: 40 QSYGPSGQYTHEFDGDEQFYVDLGRKETVWCLPVLRQFR----------FDPQFALTNIA 89
Query: 111 QIGPKLDGKIPVSRG------FPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNW--Q 162
+ L+ I S P VF+ P+ G+PN L+C V N+FPP++ + W
Sbjct: 90 VLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVTLGQPNILICLVDNIFPPVVNITWLSN 149
Query: 163 HHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNA 222
HSV EG T + SF SYL P + + C V H + +W P
Sbjct: 150 GHSV-TEGVSETSFLSKSDHSFFKISYLTLLPSAEESYDCKVEHWGLDKPLLKHWEPEIP 208
Query: 223 LP-SDLLENVLCGVAFGLGVLGIIVGIVLII 252
P S+L E V+C + +G++GI+VG V II
Sbjct: 209 APMSELTETVVCALGLSVGLVGIVVGTVFII 239
>gi|239513953 PREDICTED: similar to major histocompatibility
complex, class II, DQ alpha 1 [Homo sapiens]
Length = 254
Score = 90.1 bits (222), Expect = 2e-18
Identities = 63/211 (29%), Positives = 92/211 (43%), Gaps = 20/211 (9%)
Query: 51 QDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQ 110
Q PS + +D D+ F+ D + V LP + FD +F I
Sbjct: 40 QSYGPSGQYTHEFDGDEQFYVDLGRKETVWCLPVLRQFR----------FDPQFALTNIA 89
Query: 111 QIGPKLDGKIPVSRG------FPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNW--Q 162
+ L+ I S P VF+ P+ G+PN L+C V N+FPP++ + W
Sbjct: 90 VLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVTLGQPNILICLVDNIFPPVVNITWLSN 149
Query: 163 HHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNA 222
HSV EG T + SF SYL P + + C V H + +W P
Sbjct: 150 GHSV-TEGVSETSFLSKSDHSFFKISYLTLLPSAEESYDCKVEHWGLDKPLLKHWEPEIP 208
Query: 223 LP-SDLLENVLCGVAFGLGVLGIIVGIVLII 252
P S+L E V+C + +G++GI+VG V II
Sbjct: 209 APMSELTETVVCALGLSVGLVGIVVGTVFII 239
>gi|169218140 PREDICTED: similar to major histocompatibility
complex, class II, DQ alpha 1, partial [Homo sapiens]
Length = 153
Score = 83.6 bits (205), Expect = 2e-16
Identities = 46/129 (35%), Positives = 66/129 (51%), Gaps = 4/129 (3%)
Query: 127 PIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNW--QHHSVPVEGFGPTFVSAVDGLSF 184
P VF+ P+ G+PN L+C V N+FPP++ + W HSV EG T + SF
Sbjct: 11 PEVTVFSKSPVTLGQPNILICLVDNIFPPVVNITWLSNGHSV-TEGVSETSFLSKSDHSF 69
Query: 185 QAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALP-SDLLENVLCGVAFGLGVLG 243
SYL P + + C V H + +W P P S+L E V+C + +G++G
Sbjct: 70 FKISYLTLLPSAEESYDCKVEHWGLDKPLLKHWEPEIPAPMSELTETVVCALGLSVGLVG 129
Query: 244 IIVGIVLII 252
I+VG V II
Sbjct: 130 IVVGTVFII 138
>gi|4504399 major histocompatibility complex, class II, DM beta
precursor [Homo sapiens]
Length = 263
Score = 48.5 bits (114), Expect = 6e-06
Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 3/125 (2%)
Query: 127 PIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPVEGFGPTFVSAVDG--LSF 184
P +V P +P L C+V +P +T+ W+ + V +A ++
Sbjct: 115 PSVQVAKTTPFNTREPVMLACYVWGFYPAEVTITWRKNGKLVMPHSSAHKTAQPNGDWTY 174
Query: 185 QAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGI 244
Q S+L TP D ++C+V H + W P P L+ + V GLG++
Sbjct: 175 QTLSHLALTPSYGDTYTCVVEHIGAPEPILRDWTP-GLSPMQTLKVSVSAVTLGLGLIIF 233
Query: 245 IVGIV 249
+G++
Sbjct: 234 SLGVI 238
>gi|239752152 PREDICTED: hypothetical protein XP_002348153 [Homo
sapiens]
Length = 264
Score = 46.6 bits (109), Expect = 2e-05
Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 4/68 (5%)
Query: 144 TLVCFVSNLFPPMLTVNWQHHSVPVE-GFGPTFVSAVDGLSFQAFSYLNFTPE---PSDI 199
TLVC +S+ +P +TV W+ S PV+ G T S + A SYL+ TPE
Sbjct: 183 TLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRS 242
Query: 200 FSCIVTHE 207
+SC VTHE
Sbjct: 243 YSCQVTHE 250
>gi|4757826 beta-2-microglobulin precursor [Homo sapiens]
Length = 119
Score = 44.7 bits (104), Expect = 8e-05
Identities = 27/91 (29%), Positives = 39/91 (42%)
Query: 127 PIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPVEGFGPTFVSAVDGLSFQA 186
P +V++ P E GK N L C+VS P + V+ + +E + +S SF
Sbjct: 25 PKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYL 84
Query: 187 FSYLNFTPEPSDIFSCIVTHEIDRYTAIAYW 217
Y FTP D ++C V H I W
Sbjct: 85 LYYTEFTPTEKDEYACRVNHVTLSQPKIVKW 115
>gi|239740920 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
Length = 261
Score = 43.9 bits (102), Expect = 1e-04
Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 5/114 (4%)
Query: 143 NTLVCFVSNLFPPMLTVNW-QHHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFS 201
N LVC V++ +P + V W ++ G T + +FQ L TP+ D+++
Sbjct: 145 NLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYT 204
Query: 202 CIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFR 255
C V H + I W ++ + + + G GL I +G+ LII+ R
Sbjct: 205 CHVEHPSLQNPIIVEWRAQSESAQSKMLSGIGGFVLGL----IFLGLGLIIHHR 254
>gi|239740918 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
Length = 281
Score = 43.9 bits (102), Expect = 1e-04
Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 5/114 (4%)
Query: 143 NTLVCFVSNLFPPMLTVNW-QHHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFS 201
N LVC V++ +P + V W ++ G T + +FQ L TP+ D+++
Sbjct: 145 NLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYT 204
Query: 202 CIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFR 255
C V H + I W ++ + + + G GL I +G+ LII+ R
Sbjct: 205 CHVEHPSLQNPIIVEWRAQSESAQSKMLSGIGGFVLGL----IFLGLGLIIHHR 254
>gi|13399298 immunoglobulin lambda-like polypeptide 1 isoform a
precursor [Homo sapiens]
Length = 213
Score = 43.9 bits (102), Expect = 1e-04
Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 4/68 (5%)
Query: 144 TLVCFVSNLFPPMLTVNWQHHSVPV-EGFGPTFVSAVDGLSFQAFSYLNFTPE---PSDI 199
TLVC +++ +P +LTV W+ P+ +G T S + A SYL+ TPE
Sbjct: 132 TLVCLMNDFYPGILTVTWKADGTPITQGVEMTTPSKQSNNKYAASSYLSLTPEQWRSRRS 191
Query: 200 FSCIVTHE 207
+SC V HE
Sbjct: 192 YSCQVMHE 199
>gi|169168591 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 1 [Homo sapiens]
Length = 261
Score = 42.0 bits (97), Expect = 5e-04
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 5/114 (4%)
Query: 143 NTLVCFVSNLFPPMLTVNW-QHHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFS 201
N LVC V++ +P + V W ++ G T + +FQ L TP+ D+++
Sbjct: 145 NLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYT 204
Query: 202 CIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFR 255
C V H + W ++ + + + G GL I +G+ LII+ R
Sbjct: 205 CHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGL----IFLGLGLIIHHR 254
>gi|239748788 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 2 [Homo sapiens]
Length = 281
Score = 42.0 bits (97), Expect = 5e-04
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 5/114 (4%)
Query: 143 NTLVCFVSNLFPPMLTVNW-QHHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFS 201
N LVC V++ +P + V W ++ G T + +FQ L TP+ D+++
Sbjct: 145 NLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYT 204
Query: 202 CIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFR 255
C V H + W ++ + + + G GL I +G+ LII+ R
Sbjct: 205 CHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGL----IFLGLGLIIHHR 254
>gi|239740863 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 42.0 bits (97), Expect = 5e-04
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 5/114 (4%)
Query: 143 NTLVCFVSNLFPPMLTVNW-QHHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFS 201
N LVC V++ +P + V W ++ G T + +FQ L TP+ D+++
Sbjct: 145 NLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYT 204
Query: 202 CIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFR 255
C V H + W ++ + + + G GL I +G+ LII+ R
Sbjct: 205 CHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGL----IFLGLGLIIHHR 254
>gi|239513955 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 42.0 bits (97), Expect = 5e-04
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 5/114 (4%)
Query: 143 NTLVCFVSNLFPPMLTVNW-QHHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFS 201
N LVC V++ +P + V W ++ G T + +FQ L TP+ D+++
Sbjct: 145 NLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYT 204
Query: 202 CIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFR 255
C V H + W ++ + + + G GL I +G+ LII+ R
Sbjct: 205 CHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGL----IFLGLGLIIHHR 254
>gi|239758095 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 41.6 bits (96), Expect = 7e-04
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 5/114 (4%)
Query: 143 NTLVCFVSNLFPPMLTVNW-QHHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFS 201
N LVC V++ +P + V W ++ G T + +FQ L TP+ D+++
Sbjct: 145 NLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYT 204
Query: 202 CIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFR 255
C V H + W ++ + + + G GL I +G+ LII+ R
Sbjct: 205 CHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGL----IFLGLGLIIHHR 254
>gi|239740749 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 41.6 bits (96), Expect = 7e-04
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 5/114 (4%)
Query: 143 NTLVCFVSNLFPPMLTVNW-QHHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFS 201
N LVC V++ +P + V W ++ G T + +FQ L TP+ D+++
Sbjct: 145 NLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYT 204
Query: 202 CIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFR 255
C V H + W ++ + + + G GL I +G+ LII+ R
Sbjct: 205 CHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGL----IFLGLGLIIHHR 254
>gi|17986005 major histocompatibility complex, class II, DR beta 3
precursor [Homo sapiens]
Length = 266
Score = 41.2 bits (95), Expect = 0.001
Identities = 33/133 (24%), Positives = 50/133 (37%), Gaps = 5/133 (3%)
Query: 124 RGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNW-QHHSVPVEGFGPTFVSAVDGL 182
R P V+ K N LVC VS +P + V W ++ G T +
Sbjct: 123 RVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDW 182
Query: 183 SFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVL 242
+FQ L P ++++C V H W R+ + + + G GL
Sbjct: 183 TFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGL--- 239
Query: 243 GIIVGIVLIIYFR 255
+ +G L IYFR
Sbjct: 240 -LFLGAGLFIYFR 251
>gi|239740855 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 3 isoform 1 [Homo sapiens]
Length = 267
Score = 41.2 bits (95), Expect = 0.001
Identities = 33/133 (24%), Positives = 50/133 (37%), Gaps = 5/133 (3%)
Query: 124 RGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNW-QHHSVPVEGFGPTFVSAVDGL 182
R P V+ K N LVC VS +P + V W ++ G T +
Sbjct: 124 RVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDW 183
Query: 183 SFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVL 242
+FQ L P ++++C V H W R+ + + + G GL
Sbjct: 184 TFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARSESAQSKMLSGVGGFVLGL--- 240
Query: 243 GIIVGIVLIIYFR 255
+ +G L IYFR
Sbjct: 241 -LFLGAGLFIYFR 252
>gi|239740853 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 3 isoform 2 [Homo sapiens]
Length = 266
Score = 41.2 bits (95), Expect = 0.001
Identities = 33/133 (24%), Positives = 50/133 (37%), Gaps = 5/133 (3%)
Query: 124 RGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNW-QHHSVPVEGFGPTFVSAVDGL 182
R P V+ K N LVC VS +P + V W ++ G T +
Sbjct: 123 RVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDW 182
Query: 183 SFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVL 242
+FQ L P ++++C V H W R+ + + + G GL
Sbjct: 183 TFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARSESAQSKMLSGVGGFVLGL--- 239
Query: 243 GIIVGIVLIIYFR 255
+ +G L IYFR
Sbjct: 240 -LFLGAGLFIYFR 251
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.142 0.468
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,642,800
Number of Sequences: 37866
Number of extensions: 584775
Number of successful extensions: 1156
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 1058
Number of HSP's gapped (non-prelim): 66
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.