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Search of human proteins with 187281580
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|187281580 meckelin isoform 1 [Homo sapiens]
(995 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|187281580 meckelin isoform 1 [Homo sapiens] 2015 0.0
gi|214830753 meckelin isoform 2 [Homo sapiens] 1731 0.0
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 46 2e-04
gi|66346695 fibrillin 2 precursor [Homo sapiens] 43 0.001
gi|56237021 fibrillin 3 precursor [Homo sapiens] 43 0.001
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 42 0.004
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 40 0.011
gi|221316650 ephrin receptor EphA1 [Homo sapiens] 40 0.014
gi|24430141 fibrillin 1 precursor [Homo sapiens] 39 0.032
gi|116284392 mucin 2 precursor [Homo sapiens] 37 0.092
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 37 0.092
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 37 0.092
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 37 0.092
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 37 0.092
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 37 0.092
gi|112420992 crumbs homolog 2 [Homo sapiens] 37 0.12
gi|46249414 latent transforming growth factor beta binding prote... 36 0.16
gi|46249412 latent transforming growth factor beta binding prote... 36 0.16
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 36 0.16
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 36 0.16
gi|116235485 delta-notch-like EGF repeat-containing transmembran... 36 0.16
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens] 36 0.21
gi|219842266 usherin isoform B [Homo sapiens] 35 0.35
gi|219842259 usherin isoform A [Homo sapiens] 35 0.35
gi|148833508 notch1 preproprotein [Homo sapiens] 34 0.60
gi|153946395 tenascin C precursor [Homo sapiens] 34 0.60
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 34 0.60
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 34 0.60
gi|61743978 stabilin 1 precursor [Homo sapiens] 34 0.78
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 34 0.78
>gi|187281580 meckelin isoform 1 [Homo sapiens]
Length = 995
Score = 2015 bits (5221), Expect = 0.0
Identities = 995/995 (100%), Positives = 995/995 (100%)
Query: 1 MATRGGAGVAMAVWSLLSARAVTAFLLLFLPRFLQAQTFSFPFQQPEKCDNNQYFDISAL 60
MATRGGAGVAMAVWSLLSARAVTAFLLLFLPRFLQAQTFSFPFQQPEKCDNNQYFDISAL
Sbjct: 1 MATRGGAGVAMAVWSLLSARAVTAFLLLFLPRFLQAQTFSFPFQQPEKCDNNQYFDISAL 60
Query: 61 SCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCISCPSD 120
SCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCISCPSD
Sbjct: 61 SCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCISCPSD 120
Query: 121 LTAEGKCHCPIGHILVERDINGTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTFVNT 180
LTAEGKCHCPIGHILVERDINGTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTFVNT
Sbjct: 121 LTAEGKCHCPIGHILVERDINGTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTFVNT 180
Query: 181 SRSCACSEPNILTGGLCFSSTGNFPLRRISAARYGEVGMSLTSEWFAKYLQSSAAACWVY 240
SRSCACSEPNILTGGLCFSSTGNFPLRRISAARYGEVGMSLTSEWFAKYLQSSAAACWVY
Sbjct: 181 SRSCACSEPNILTGGLCFSSTGNFPLRRISAARYGEVGMSLTSEWFAKYLQSSAAACWVY 240
Query: 241 ANLTSCQALGNMCVMNMNSYDFATFDACGLFQFIFENTAGLSTVHSISFWRQNLPWLFYG 300
ANLTSCQALGNMCVMNMNSYDFATFDACGLFQFIFENTAGLSTVHSISFWRQNLPWLFYG
Sbjct: 241 ANLTSCQALGNMCVMNMNSYDFATFDACGLFQFIFENTAGLSTVHSISFWRQNLPWLFYG 300
Query: 301 DQLGLAPQVLSSTSLPTNFSFKGENQNTKLKFVAASYDIRGNFLKWQTLEGGVLQLCPDT 360
DQLGLAPQVLSSTSLPTNFSFKGENQNTKLKFVAASYDIRGNFLKWQTLEGGVLQLCPDT
Sbjct: 301 DQLGLAPQVLSSTSLPTNFSFKGENQNTKLKFVAASYDIRGNFLKWQTLEGGVLQLCPDT 360
Query: 361 ETRLNAAYSFGTTYQQNCEIPISKILIDFPTPIFYDVYLEYTDENQHQYILAVPVLNLNL 420
ETRLNAAYSFGTTYQQNCEIPISKILIDFPTPIFYDVYLEYTDENQHQYILAVPVLNLNL
Sbjct: 361 ETRLNAAYSFGTTYQQNCEIPISKILIDFPTPIFYDVYLEYTDENQHQYILAVPVLNLNL 420
Query: 421 QHNKIFVNQDSNSGKWLLTRRIFLVDAVSGRENDLGTQPRVIRVATQISLSVHLVPNTIN 480
QHNKIFVNQDSNSGKWLLTRRIFLVDAVSGRENDLGTQPRVIRVATQISLSVHLVPNTIN
Sbjct: 421 QHNKIFVNQDSNSGKWLLTRRIFLVDAVSGRENDLGTQPRVIRVATQISLSVHLVPNTIN 480
Query: 481 GNIYPPLITIAYSDIDIKDANSQSVKVSFSVTYEMDHGEAHVQTDIALGVLGGLAVLASL 540
GNIYPPLITIAYSDIDIKDANSQSVKVSFSVTYEMDHGEAHVQTDIALGVLGGLAVLASL
Sbjct: 481 GNIYPPLITIAYSDIDIKDANSQSVKVSFSVTYEMDHGEAHVQTDIALGVLGGLAVLASL 540
Query: 541 LKTAGWKRRIGSPMIDLQTVVKFLVYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLL 600
LKTAGWKRRIGSPMIDLQTVVKFLVYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLL
Sbjct: 541 LKTAGWKRRIGSPMIDLQTVVKFLVYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLL 600
Query: 601 PMPIQEERFVTYVGCAFALKALQFLHKLISQITIDVFFIDWERPKGKVLKAVEGEGGVRS 660
PMPIQEERFVTYVGCAFALKALQFLHKLISQITIDVFFIDWERPKGKVLKAVEGEGGVRS
Sbjct: 601 PMPIQEERFVTYVGCAFALKALQFLHKLISQITIDVFFIDWERPKGKVLKAVEGEGGVRS 660
Query: 661 ATVPVSIWRTYFVANEWNEIQTVRKINSLFQVLTVLFFLEVVGFKNLALMDSSSSLSRNP 720
ATVPVSIWRTYFVANEWNEIQTVRKINSLFQVLTVLFFLEVVGFKNLALMDSSSSLSRNP
Sbjct: 661 ATVPVSIWRTYFVANEWNEIQTVRKINSLFQVLTVLFFLEVVGFKNLALMDSSSSLSRNP 720
Query: 721 PSYIAPYSCILRYAVSAALWLAIGIIQVVFFAVFYERFIEDKIRQFVDLCSMSNISVFLL 780
PSYIAPYSCILRYAVSAALWLAIGIIQVVFFAVFYERFIEDKIRQFVDLCSMSNISVFLL
Sbjct: 721 PSYIAPYSCILRYAVSAALWLAIGIIQVVFFAVFYERFIEDKIRQFVDLCSMSNISVFLL 780
Query: 781 SHKCFGYYIHGRSVHGHADTNMEEMNMNLKREAENLCSQRGLVPNTDGQTFEIAISNQMR 840
SHKCFGYYIHGRSVHGHADTNMEEMNMNLKREAENLCSQRGLVPNTDGQTFEIAISNQMR
Sbjct: 781 SHKCFGYYIHGRSVHGHADTNMEEMNMNLKREAENLCSQRGLVPNTDGQTFEIAISNQMR 840
Query: 841 QHYDRIHETLIRKNGPARLLSSSASTFEQSIKAYHMMNKFLGSFIDHVHKEMDYFIKDKL 900
QHYDRIHETLIRKNGPARLLSSSASTFEQSIKAYHMMNKFLGSFIDHVHKEMDYFIKDKL
Sbjct: 841 QHYDRIHETLIRKNGPARLLSSSASTFEQSIKAYHMMNKFLGSFIDHVHKEMDYFIKDKL 900
Query: 901 LLERILGMEFMEPMEKSIFYNDEGYSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFILA 960
LLERILGMEFMEPMEKSIFYNDEGYSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFILA
Sbjct: 901 LLERILGMEFMEPMEKSIFYNDEGYSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFILA 960
Query: 961 SFLTYLQQEIFRYIRNTVGQKNLASKTLVDQRFLI 995
SFLTYLQQEIFRYIRNTVGQKNLASKTLVDQRFLI
Sbjct: 961 SFLTYLQQEIFRYIRNTVGQKNLASKTLVDQRFLI 995
>gi|214830753 meckelin isoform 2 [Homo sapiens]
Length = 914
Score = 1731 bits (4483), Expect = 0.0
Identities = 873/915 (95%), Positives = 883/915 (96%), Gaps = 8/915 (0%)
Query: 82 PGFQMISNNGGPAIICKKCPENMKGVT-EDGWNCISCPSDLTAEGKCHCPIGHILVERDI 140
P F+++ N P +IC P + G E ++C T EG + I ++ERDI
Sbjct: 7 PYFRLVLNFR-PQVICLPQPPKVLGYRLEPPHLTLAC----TLEGMYN--IIEEILERDI 59
Query: 141 NGTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTFVNTSRSCACSEPNILTGGLCFSS 200
NGTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTFVNTSRSCACSEPNILTGGLCFSS
Sbjct: 60 NGTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTFVNTSRSCACSEPNILTGGLCFSS 119
Query: 201 TGNFPLRRISAARYGEVGMSLTSEWFAKYLQSSAAACWVYANLTSCQALGNMCVMNMNSY 260
TGNFPLRRISAARYGEVGMSLTSEWFAKYLQSSAAACWVYANLTSCQALGNMCVMNMNSY
Sbjct: 120 TGNFPLRRISAARYGEVGMSLTSEWFAKYLQSSAAACWVYANLTSCQALGNMCVMNMNSY 179
Query: 261 DFATFDACGLFQFIFENTAGLSTVHSISFWRQNLPWLFYGDQLGLAPQVLSSTSLPTNFS 320
DFATFDACGLFQFIFENTAGLSTVHSISFWRQNLPWLFYGDQLGLAPQVLSSTSLPTNFS
Sbjct: 180 DFATFDACGLFQFIFENTAGLSTVHSISFWRQNLPWLFYGDQLGLAPQVLSSTSLPTNFS 239
Query: 321 FKGENQNTKLKFVAASYDIRGNFLKWQTLEGGVLQLCPDTETRLNAAYSFGTTYQQNCEI 380
FKGENQNTKLKFVAASYDIRGNFLKWQTLEGGVLQLCPDTETRLNAAYSFGTTYQQNCEI
Sbjct: 240 FKGENQNTKLKFVAASYDIRGNFLKWQTLEGGVLQLCPDTETRLNAAYSFGTTYQQNCEI 299
Query: 381 PISKILIDFPTPIFYDVYLEYTDENQHQYILAVPVLNLNLQHNKIFVNQDSNSGKWLLTR 440
PISKILIDFPTPIFYDVYLEYTDENQHQYILAVPVLNLNLQHNKIFVNQDSNSGKWLLTR
Sbjct: 300 PISKILIDFPTPIFYDVYLEYTDENQHQYILAVPVLNLNLQHNKIFVNQDSNSGKWLLTR 359
Query: 441 RIFLVDAVSGRENDLGTQPRVIRVATQISLSVHLVPNTINGNIYPPLITIAYSDIDIKDA 500
RIFLVDAVSGRENDLGTQPRVIRVATQISLSVHLVPNTINGNIYPPLITIAYSDIDIKDA
Sbjct: 360 RIFLVDAVSGRENDLGTQPRVIRVATQISLSVHLVPNTINGNIYPPLITIAYSDIDIKDA 419
Query: 501 NSQSVKVSFSVTYEMDHGEAHVQTDIALGVLGGLAVLASLLKTAGWKRRIGSPMIDLQTV 560
NSQSVKVSFSVTYEMDHGEAHVQTDIALGVLGGLAVLASLLKTAGWKRRIGSPMIDLQTV
Sbjct: 420 NSQSVKVSFSVTYEMDHGEAHVQTDIALGVLGGLAVLASLLKTAGWKRRIGSPMIDLQTV 479
Query: 561 VKFLVYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLLPMPIQEERFVTYVGCAFALK 620
VKFLVYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLLPMPIQEERFVTYVGCAFALK
Sbjct: 480 VKFLVYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLLPMPIQEERFVTYVGCAFALK 539
Query: 621 ALQFLHKLISQITIDVFFIDWERPKGKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEI 680
ALQFLHKLISQITIDVFFIDWERPKGKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEI
Sbjct: 540 ALQFLHKLISQITIDVFFIDWERPKGKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEI 599
Query: 681 QTVRKINSLFQVLTVLFFLEVVGFKNLALMDSSSSLSRNPPSYIAPYSCILRYAVSAALW 740
QTVRKINSLFQVLTVLFFLEVVGFKNLALMDSSSSLSRNPPSYIAPYSCILRYAVSAALW
Sbjct: 600 QTVRKINSLFQVLTVLFFLEVVGFKNLALMDSSSSLSRNPPSYIAPYSCILRYAVSAALW 659
Query: 741 LAIGIIQVVFFAVFYERFIEDKIRQFVDLCSMSNISVFLLSHKCFGYYIHGRSVHGHADT 800
LAIGIIQVVFFAVFYERFIEDKIRQFVDLCSMSNISVFLLSHKCFGYYIHGRSVHGHADT
Sbjct: 660 LAIGIIQVVFFAVFYERFIEDKIRQFVDLCSMSNISVFLLSHKCFGYYIHGRSVHGHADT 719
Query: 801 NMEEMNMNLKREAENLCSQRGLVPNTDGQTFEIAISNQMRQHYDRIHETLIRKNGPARLL 860
NMEEMNMNLKREAENLCSQRGLVPNTDGQTFEIAISNQMRQHYDRIHETLIRKNGPARLL
Sbjct: 720 NMEEMNMNLKREAENLCSQRGLVPNTDGQTFEIAISNQMRQHYDRIHETLIRKNGPARLL 779
Query: 861 SSSASTFEQSIKAYHMMNKFLGSFIDHVHKEMDYFIKDKLLLERILGMEFMEPMEKSIFY 920
SSSASTFEQSIKAYHMMNKFLGSFIDHVHKEMDYFIKDKLLLERILGMEFMEPMEKSIFY
Sbjct: 780 SSSASTFEQSIKAYHMMNKFLGSFIDHVHKEMDYFIKDKLLLERILGMEFMEPMEKSIFY 839
Query: 921 NDEGYSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFILASFLTYLQQEIFRYIRNTVGQ 980
NDEGYSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFILASFLTYLQQEIFRYIRNTVGQ
Sbjct: 840 NDEGYSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFILASFLTYLQQEIFRYIRNTVGQ 899
Query: 981 KNLASKTLVDQRFLI 995
KNLASKTLVDQRFLI
Sbjct: 900 KNLASKTLVDQRFLI 914
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 45.8 bits (107), Expect = 2e-04
Identities = 42/154 (27%), Positives = 60/154 (38%), Gaps = 44/154 (28%)
Query: 58 SALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCISC 117
SA C+PC N R C P + +GG C C +N DG +C C
Sbjct: 335 SASECLPCDCN----GRSQECYFDPELYRSTGHGGH---CTNCQDNT-----DGAHCERC 382
Query: 118 PSDLTAEGK------CHC-PIGHILVERDINGTLLSQATCELCDGNENSFMVVNALGDRC 170
+ G CHC P+G + + D G + +C+ +GD+C
Sbjct: 383 RENFFRLGNNEACSSCHCSPVGSLSTQCDSYG----RCSCK-----------PGVMGDKC 427
Query: 171 VRCEPTFVNTS----RSCAC------SEPNILTG 194
RC+P F + + R C+C E NI TG
Sbjct: 428 DRCQPGFHSLTEAGCRPCSCDPSGSIDECNIETG 461
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 43.1 bits (100), Expect = 0.001
Identities = 43/163 (26%), Positives = 64/163 (39%), Gaps = 19/163 (11%)
Query: 50 DNNQYFDISALSCVPCGANQRQDARGT-SCVCLPGFQMISNNGGPAIICKKCPENMKGVT 108
D D+ PCG ++ G+ +C+C PGF++ NN + +C V
Sbjct: 1928 DQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNN--DCLDIDECSSFFGQVC 1985
Query: 109 EDG--WNCISCPSDLTAEGKCHCPIGHILVERDINGTLLSQATCELCDGNENSFMVVNAL 166
+G +N I L EG P G ++ + L + C E SF
Sbjct: 1986 RNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSF------ 2039
Query: 167 GDRCVRCEPTFVNTSRSC----ACSE-PNILTGGLCFSSTGNF 204
RC+ C P + S +C C E PNI G C ++ G F
Sbjct: 2040 --RCI-CPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGF 2079
Score = 40.4 bits (93), Expect = 0.008
Identities = 43/171 (25%), Positives = 61/171 (35%), Gaps = 44/171 (25%)
Query: 46 PEKCDNNQYFDISALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPA-IICKKCPENM 104
P C N Q + C D GTSC+ L S + P ICK
Sbjct: 2457 PNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDL---DECSQSPKPCNYICKN----- 2508
Query: 105 KGVTEDGWNCISCPSDLTAEGKCHCPIGHILVE-----RDINGTLLSQATCELCDGNENS 159
TE + +C CP G++L E +D++ Q C+
Sbjct: 2509 ---TEGSY-------------QCSCPRGYVLQEDGKTCKDLDECQTKQHNCQ-------- 2544
Query: 160 FMVVNALGDRCVRCEPTFVNTSRSC----ACSEPNILTG--GLCFSSTGNF 204
F+ VN LG +C P F +C C L G G+C ++ G+F
Sbjct: 2545 FLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSF 2595
Score = 35.8 bits (81), Expect = 0.21
Identities = 38/174 (21%), Positives = 59/174 (33%), Gaps = 26/174 (14%)
Query: 48 KCDNNQYFDISALSCV---------PCGANQRQDARGT-SCVCLPGFQMISNNGGPAIIC 97
+C D + + CV PCG + G+ C C GF+ GP + C
Sbjct: 2197 ECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEP-----GPMMNC 2251
Query: 98 KKCPENMKGVTEDGWNCISCPSDLTAEGKCHCPIGHILVERDINGTLLSQATCELCDGNE 157
+ E + + C++ +C CPIG+ L E L + L D
Sbjct: 2252 EDINECAQNPLLCAFRCMNTFGSY----ECTCPIGYALREDQKMCKDLDECAEGLHDCES 2307
Query: 158 NSFMVVNALGDRCVRCEPTFVNTSRSCAC-------SEPNILTGGLCFSSTGNF 204
M N +G C P C ++P I G C + G++
Sbjct: 2308 RGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSY 2361
Score = 34.7 bits (78), Expect = 0.46
Identities = 43/165 (26%), Positives = 57/165 (34%), Gaps = 42/165 (25%)
Query: 75 GTSCVCLPGFQMISNNG-----------------GPAII--------CKKCPENMKGVTE 109
G C+C PGF ++S+NG G + K C M G
Sbjct: 2078 GFQCLCPPGF-VLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPG--- 2133
Query: 110 DGWN--CISCPSDLTAEGKCHCPIGHILV------ERDINGTLLSQATCE--LCDGNENS 159
+GW C CP D + CP GH V D+N L S C C + S
Sbjct: 2134 EGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGS 2193
Query: 160 FMVVNALGDRCVRCEPTFVNTSRSCACSEPNILTGGLCFSSTGNF 204
F +G + T V + CS N G C + G+F
Sbjct: 2194 FRCECPMG---YNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSF 2235
Score = 33.9 bits (76), Expect = 0.78
Identities = 39/155 (25%), Positives = 60/155 (38%), Gaps = 31/155 (20%)
Query: 65 CGANQRQDARGT-SCVCLPGFQ---MISNNGGPAIICKKCPENMKGVTEDGWNCISCPSD 120
CG+ + G+ C C G++ M+ N C++ P +G T C++
Sbjct: 1126 CGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGT-----CVNTEGS 1180
Query: 121 LTAEGKCHCPIGHILVER-----DINGTLLSQATCELCDGNENSFMVVNALGDRCVRCEP 175
+C CP+GH L DIN C L D + VN +G C P
Sbjct: 1181 F----QCDCPLGHELSPSREDCVDIN-------ECSLSDNLCRNGKCVNMIGTYQCSCNP 1229
Query: 176 TFVNTSRSCACS---EPNILTGGL---CFSSTGNF 204
+ T C+ E I+ GG C +S G++
Sbjct: 1230 GYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSY 1264
Score = 32.7 bits (73), Expect = 1.7
Identities = 44/172 (25%), Positives = 65/172 (37%), Gaps = 39/172 (22%)
Query: 51 NNQYFDISALSCVPCGANQRQDARGTS-CVCLPGFQMISNNGG---------PAIICKKC 100
N D+ + PC + G+ C C GFQ ++CK
Sbjct: 530 NGDCIDVDECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCK-- 587
Query: 101 PENMKGVTEDG-WNCI-SCPSDLTAEGKCHCPIGHILVERDINGTLLSQATCELCDGNEN 158
N + V DG + CI + +LT +GK +C V+ D T + +C +
Sbjct: 588 --NGRCVNTDGSFQCICNAGFELTTDGK-NC------VDHD-ECTTTNMCLNGMCINEDG 637
Query: 159 SFMVVNALGDRCVRCEPTFV--NTSRSCA----CSEPNILTGGLCFSSTGNF 204
SF +C+ C+P FV R C C P I G C +S G+F
Sbjct: 638 SF--------KCI-CKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSF 680
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 43.1 bits (100), Expect = 0.001
Identities = 50/173 (28%), Positives = 69/173 (39%), Gaps = 39/173 (22%)
Query: 50 DNNQYFDISALSCVPCGANQRQDARGT-SCVCLPGFQMISNNGGPAIICKKCPENMKGVT 108
D DI PCG ++ G+ +C+C PGF + N G + +C + V
Sbjct: 1841 DQTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHN--GDCVDFDECTTLVGQVC 1898
Query: 109 EDGWNCISCPS----------DLTAEGKCHCPIGHILVERDINGTLLSQATC--ELCDGN 156
G +C++ +LTA+GK +C D N L TC C
Sbjct: 1899 RFG-HCLNTAGSFHCLCQDGFELTADGK-NCV--------DTNECLSLAGTCLPGTCQNL 1948
Query: 157 ENSFMVVNALGDRCVRCEPTFVNTSRSCA----CSE-PNILTGGLCFSSTGNF 204
E SF RC+ C P F S C CSE PN+ G C +S G+F
Sbjct: 1949 EGSF--------RCI-CPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSF 1992
Score = 35.4 bits (80), Expect = 0.27
Identities = 39/151 (25%), Positives = 57/151 (37%), Gaps = 23/151 (15%)
Query: 65 CGANQRQDARGT-SCVCLPGFQ---MISNNGGPAIICKKCPENMKGVTEDGWNCISCPSD 120
CG + G+ C C PG++ M+ N C + P +G T C ++
Sbjct: 1039 CGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGT--------C-TN 1089
Query: 121 LTAEGKCHCPIGHILVERDINGTLLSQA-TCELCDGNENSFMVVNALGDRCVRCEPTFVN 179
KC CP GH L + GT C L DG VN +G C F +
Sbjct: 1090 TDGSYKCQCPPGHELTAK---GTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQS 1146
Query: 180 TSRSCAC---SEPNILTGGL---CFSSTGNF 204
T C +E + GG C ++ G++
Sbjct: 1147 TPDRQGCVDINECRVQNGGCDVHCINTEGSY 1177
Score = 32.7 bits (73), Expect = 1.7
Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 19/89 (21%)
Query: 127 CHCPIGHILVE-----RDINGTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTFVNTS 181
C CP G++L E +D++ Q C+ F+ VN +G RC P F
Sbjct: 2429 CSCPRGYLLEEDGRTCKDLDECTSRQHNCQ--------FLCVNTVGAFTCRCPPGFTQHH 2480
Query: 182 RSC----ACSEPNILTG--GLCFSSTGNF 204
++C CS G G C ++ G+F
Sbjct: 2481 QACFDNDECSAQPGPCGAHGHCHNTPGSF 2509
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 41.6 bits (96), Expect = 0.004
Identities = 36/145 (24%), Positives = 51/145 (35%), Gaps = 32/145 (22%)
Query: 49 CDNNQ--YFDISALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPENMKG 106
CD Q Y+ S C+PC N R SC L G + C++C E
Sbjct: 320 CDRCQDGYYGFSKNGCLPCQCNNRS----ASCDALTGACLNCQENSKGNHCEECKEGFYQ 375
Query: 107 VTEDGWNCISCP-SDLTAEGKCHCPIGHILVERDINGTLLSQATCELC-DGNENSFMVVN 164
+ C+ CP S +T+ G C + + C+ C DG
Sbjct: 376 SPDATKECLRCPCSAVTSTGSCSIKSSEL------------EPECDQCKDG--------- 414
Query: 165 ALGDRCVRCEPTFVN---TSRSCAC 186
+G C +CE + N R C C
Sbjct: 415 YIGPNCNKCENGYYNFDSICRKCQC 439
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 40.0 bits (92), Expect = 0.011
Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 16/80 (20%)
Query: 47 EKCDNNQ--YFDIS-----ALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKK 99
+ CD Q +F S A C P GA Q +CVC PGF+ C +
Sbjct: 945 QACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGTCVCRPGFE--------GYKCDR 996
Query: 100 CPENMKGVTEDGWNCISCPS 119
C +N +T DG +C CPS
Sbjct: 997 CHDNF-FLTADGTHCQQCPS 1015
>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
Length = 976
Score = 39.7 bits (91), Expect = 0.014
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 8/60 (13%)
Query: 78 CVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCISCPSDLTAEGK----CHCPIGH 133
C C PG++ GG C CP + D +C++CP TAE + C C GH
Sbjct: 262 CHCEPGYE----EGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAESEGATICTCESGH 317
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 38.5 bits (88), Expect = 0.032
Identities = 40/162 (24%), Positives = 61/162 (37%), Gaps = 47/162 (29%)
Query: 56 DISALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCI 115
D + C+ C D GTSCV L C + P+ + ++
Sbjct: 2421 DRGSYHCI-CKTGYTPDITGTSCVDLNE-------------CNQAPKPCNFICKN----- 2461
Query: 116 SCPSDLTAEG--KCHCPIGHILVE-----RDINGTLLSQATCELCDGNENSFMVVNALGD 168
EG +C CP G+IL E +D++ Q C+ F+ VN +G
Sbjct: 2462 -------TEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQ--------FLCVNTIGG 2506
Query: 169 RCVRCEPTFVNTSRSC----ACSEPNILTG--GLCFSSTGNF 204
+C P F SC C+ L G G+C ++ G+F
Sbjct: 2507 FTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSF 2548
Score = 37.4 bits (85), Expect = 0.071
Identities = 33/151 (21%), Positives = 56/151 (37%), Gaps = 21/151 (13%)
Query: 64 PCGANQRQDA-RGTSCVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCISCPSDLT 122
PCG ++ G C C GF+ GP + C+ E + + C++
Sbjct: 2175 PCGNGTCKNVIGGFECTCEEGFEP-----GPMMTCEDINECAQNPLLCAFRCVNTYGSY- 2228
Query: 123 AEGKCHCPIGHILVERDINGTLLSQATCE--LCDGNENSFMVVNALGDRCVRCEPTFVNT 180
+C CP+G++L R+ + CE D E N +G C P +
Sbjct: 2229 ---ECKCPVGYVL--REDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRR 2283
Query: 181 SRSCAC-------SEPNILTGGLCFSSTGNF 204
C ++P I G C ++ G++
Sbjct: 2284 PDGEGCVDENECQTKPGICENGRCLNTRGSY 2314
Score = 36.2 bits (82), Expect = 0.16
Identities = 27/100 (27%), Positives = 37/100 (37%), Gaps = 6/100 (6%)
Query: 111 GWNCISCPSDLTAEGKCHCPIGHILVERDINGTLLSQATCELCDGNENSFMVVNALGDRC 170
G C CP+ T+E K CP G I L C+ G +N G
Sbjct: 1571 GTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQ 1630
Query: 171 VRCEPTFV--NTSRSC----ACSEPNILTGGLCFSSTGNF 204
RC + +R C C P I G C+++ GN+
Sbjct: 1631 CRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNY 1670
Score = 35.4 bits (80), Expect = 0.27
Identities = 37/134 (27%), Positives = 54/134 (40%), Gaps = 25/134 (18%)
Query: 82 PGFQMISNNGGPAII--CKKCPENMKGVTEDGWNCISCPSDLTAEGKCHCPIGHILVERD 139
PGF + G P I C++ P GV E+G CI+ + +C CP+G
Sbjct: 1753 PGFVIDIYTGLPVDIDECREIP----GVCENGV-CIN----MVGSFRCECPVGFFY---- 1799
Query: 140 INGTLLSQATCELCDGN---ENSFMVVNALGDRCVRCEPTFVNTSRSCA-----CSE-PN 190
N LL + C + + +N G C+P + TS C E PN
Sbjct: 1800 -NDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPN 1858
Query: 191 ILTGGLCFSSTGNF 204
I + G C + G+F
Sbjct: 1859 ICSHGQCIDTVGSF 1872
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 37.0 bits (84), Expect = 0.092
Identities = 31/134 (23%), Positives = 53/134 (39%), Gaps = 22/134 (16%)
Query: 47 EKCDNNQYFDISALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPENMKG 106
+K DNN ++ A + VPC + C PGF+++ P CKKC +
Sbjct: 4951 DKVDNNTLLNVIACTHVPCNTS-----------CSPGFELME---APGECCKKCEQTHCI 4996
Query: 107 VTE-DGWNCISCPSDLTAEGKCHCPIGHILVERDINGTLLSQATCELCDGNENSFMVVNA 165
+ D + I P D ++ K +C + I+ L+S + C + S + +
Sbjct: 4997 IKRPDNQHVILKPGDFKSDPKNNCTFFSCV---KIHNQLISSVSNITCPNFDASICIPGS 5053
Query: 166 L----GDRCVRCEP 175
+ C C P
Sbjct: 5054 ITFMPNGCCKTCTP 5067
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 37.0 bits (84), Expect = 0.092
Identities = 31/134 (23%), Positives = 53/134 (39%), Gaps = 22/134 (16%)
Query: 47 EKCDNNQYFDISALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPENMKG 106
+K DNN ++ A + VPC + C PGF+++ P CKKC +
Sbjct: 2411 DKVDNNTLLNVIACTHVPCNTS-----------CSPGFELME---APGECCKKCEQTHCI 2456
Query: 107 VTE-DGWNCISCPSDLTAEGKCHCPIGHILVERDINGTLLSQATCELCDGNENSFMVVNA 165
+ D + I P D ++ K +C + I+ L+S + C + S + +
Sbjct: 2457 IKRPDNQHVILKPGDFKSDPKNNCTFFSCV---KIHNQLISSVSNITCPNFDASICIPGS 2513
Query: 166 L----GDRCVRCEP 175
+ C C P
Sbjct: 2514 ITFMPNGCCKTCTP 2527
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 37.0 bits (84), Expect = 0.092
Identities = 46/197 (23%), Positives = 66/197 (33%), Gaps = 49/197 (24%)
Query: 47 EKCDNNQYFDISALSCVPCGANQ---------------RQDARGTSCV-CLPGFQMISNN 90
EKC N +F + CVPC N +++ G C CL G+ S
Sbjct: 65 EKC-NAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR 123
Query: 91 GGPAIICKKCPENMKGVTEDGWNCIS--------CPSDLTAEGKCHCPIGHILVERDING 142
G P C+ CP + + +C C + C G+
Sbjct: 124 GAPQF-CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY------GN 176
Query: 143 TLLSQATCELCD--GNENSFMVV---------------NALGDRCVRCEPTFVNTSRSCA 185
LL +TC+ CD GN + ++ N G +C RC P + +R
Sbjct: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 236
Query: 186 CSEPNILTGGLCFSSTG 202
GG C S TG
Sbjct: 237 NCAVCNCGGGPCDSVTG 253
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 37.0 bits (84), Expect = 0.092
Identities = 46/197 (23%), Positives = 66/197 (33%), Gaps = 49/197 (24%)
Query: 47 EKCDNNQYFDISALSCVPCGANQ---------------RQDARGTSCV-CLPGFQMISNN 90
EKC N +F + CVPC N +++ G C CL G+ S
Sbjct: 65 EKC-NAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR 123
Query: 91 GGPAIICKKCPENMKGVTEDGWNCIS--------CPSDLTAEGKCHCPIGHILVERDING 142
G P C+ CP + + +C C + C G+
Sbjct: 124 GAPQF-CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY------GN 176
Query: 143 TLLSQATCELCD--GNENSFMVV---------------NALGDRCVRCEPTFVNTSRSCA 185
LL +TC+ CD GN + ++ N G +C RC P + +R
Sbjct: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 236
Query: 186 CSEPNILTGGLCFSSTG 202
GG C S TG
Sbjct: 237 NCAVCNCGGGPCDSVTG 253
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 37.0 bits (84), Expect = 0.092
Identities = 46/197 (23%), Positives = 66/197 (33%), Gaps = 49/197 (24%)
Query: 47 EKCDNNQYFDISALSCVPCGANQ---------------RQDARGTSCV-CLPGFQMISNN 90
EKC N +F + CVPC N +++ G C CL G+ S
Sbjct: 65 EKC-NAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR 123
Query: 91 GGPAIICKKCPENMKGVTEDGWNCIS--------CPSDLTAEGKCHCPIGHILVERDING 142
G P C+ CP + + +C C + C G+
Sbjct: 124 GAPQF-CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY------GN 176
Query: 143 TLLSQATCELCD--GNENSFMVV---------------NALGDRCVRCEPTFVNTSRSCA 185
LL +TC+ CD GN + ++ N G +C RC P + +R
Sbjct: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 236
Query: 186 CSEPNILTGGLCFSSTG 202
GG C S TG
Sbjct: 237 NCAVCNCGGGPCDSVTG 253
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 37.0 bits (84), Expect = 0.092
Identities = 33/134 (24%), Positives = 53/134 (39%), Gaps = 30/134 (22%)
Query: 72 DARGTSCVCLPGFQMISNNGGPAIICKK-CPENMKGVTEDGWNCISCPSDLTAEGKCHCP 130
+A G C+C PGF I C++ E ++G C + P + T CHCP
Sbjct: 377 EASGYVCICQPGF--------TGIHCEEDVNECSSNPCQNGGTCENLPGNYT----CHCP 424
Query: 131 IGHILVERDINGTLLSQATCELCDGNENSFMVVNALGDRCVR---CEPTFVNTSRSCACS 187
++ R G G + S +++ +C+ C P F + +C
Sbjct: 425 FDNL--SRTFYG------------GRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCL 470
Query: 188 EPNILTGGLCFSST 201
P+ TG LC +T
Sbjct: 471 CPSGYTGSLCEIAT 484
>gi|112420992 crumbs homolog 2 [Homo sapiens]
Length = 1285
Score = 36.6 bits (83), Expect = 0.12
Identities = 46/179 (25%), Positives = 67/179 (37%), Gaps = 31/179 (17%)
Query: 62 CVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCISCPSDL 121
CVP G D G C C+PGFQ GP +C ++ + + +L
Sbjct: 82 CVPQGP----DPTGFRCYCVPGFQ------GP-----RCELDIDECASRPCHHGATCRNL 126
Query: 122 TAEGKCHCPIGHILVERDINGTLLSQATC---ELCDGNENSFMVVNALGDRCVRCEPTFV 178
+CHCP+G+ V ++ + A C C SF V A G RC+ +
Sbjct: 127 ADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQ-LDL 185
Query: 179 NTSRSCACSEPNILTGGLCFSSTGNFPLRRISAARYGEVGMSLTSEWFAKYLQSSAAAC 237
+ +S C+ GG C F R A G G E L+ ++A C
Sbjct: 186 DECQSQPCAH-----GGTCHDLVNGF---RCDCAGTGYEGTHCERE----VLECASAPC 232
Score = 32.3 bits (72), Expect = 2.3
Identities = 46/182 (25%), Positives = 65/182 (35%), Gaps = 38/182 (20%)
Query: 66 GANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCISCPSDLTAEG 125
GA + A G C C PGF+ ++ G C P +G +C P+
Sbjct: 294 GAFSFRHAAGFLCHCPPGFEG-ADCGVEVDECASRP------CLNGGHCQDLPNGF---- 342
Query: 126 KCHCPIGHI--LVERDINGTL----LSQATC------------ELCDGNENSFMVVNALG 167
+CHCP G+ E D++ L L TC E G + S + G
Sbjct: 343 QCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQG 402
Query: 168 DRC---VRCEPTFVNTSRSCACSEPNILTGGLC-----FSSTGNFPLRRISAARYGEVGM 219
C C P F + S C P G C FS P+ + S G +G+
Sbjct: 403 HTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSVMAGSPI-QASVPAGGPLGL 461
Query: 220 SL 221
+L
Sbjct: 462 AL 463
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 36.2 bits (82), Expect = 0.16
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 16/120 (13%)
Query: 100 CPENMKGVTEDGWNCISCPS----DLTAEGKCHCPIGHILVERDINGTLLSQ-ATCELCD 154
CP +E+G NCI D+ EG C +G E +G ++Q CE D
Sbjct: 943 CPAGFMA-SEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDID 1001
Query: 155 GNENSF-----MVVNALGD-RCVRCEPTFVNTSRSCA----CSEPNILTGGLCFSSTGNF 204
N VN+ G +CV C F + C C EPN+ G C + G++
Sbjct: 1002 ECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSY 1061
>gi|46249412 latent transforming growth factor beta binding protein
1 isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 36.2 bits (82), Expect = 0.16
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 16/120 (13%)
Query: 100 CPENMKGVTEDGWNCISCPS----DLTAEGKCHCPIGHILVERDINGTLLSQ-ATCELCD 154
CP +E+G NCI D+ EG C +G E +G ++Q CE D
Sbjct: 617 CPAGFMA-SEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDID 675
Query: 155 GNENSF-----MVVNALGD-RCVRCEPTFVNTSRSCA----CSEPNILTGGLCFSSTGNF 204
N VN+ G +CV C F + C C EPN+ G C + G++
Sbjct: 676 ECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSY 735
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 36.2 bits (82), Expect = 0.16
Identities = 38/145 (26%), Positives = 52/145 (35%), Gaps = 18/145 (12%)
Query: 61 SCVPCGANQRQD-ARGTSCVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCISCPS 119
SC PC N D + SC L G +I G C+ C + G D NC C
Sbjct: 861 SCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRC 920
Query: 120 DL--TAEGKCHCPIGHILVERDINGTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTF 177
+ + CH G ++ G C+ C +F + +A G CV C
Sbjct: 921 NAGGSFSEVCHSQTGQCECRANVQG-----QRCDKC--KAGTFGLQSARG--CVPCNCNS 971
Query: 178 VNTSRSCACSEPNILTGGLCFSSTG 202
S+S C E G C+ G
Sbjct: 972 FG-SKSFDCEE-----SGQCWCQPG 990
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 36.2 bits (82), Expect = 0.16
Identities = 38/145 (26%), Positives = 52/145 (35%), Gaps = 18/145 (12%)
Query: 61 SCVPCGANQRQD-ARGTSCVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCISCPS 119
SC PC N D + SC L G +I G C+ C + G D NC C
Sbjct: 861 SCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRC 920
Query: 120 DL--TAEGKCHCPIGHILVERDINGTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTF 177
+ + CH G ++ G C+ C +F + +A G CV C
Sbjct: 921 NAGGSFSEVCHSQTGQCECRANVQG-----QRCDKC--KAGTFGLQSARG--CVPCNCNS 971
Query: 178 VNTSRSCACSEPNILTGGLCFSSTG 202
S+S C E G C+ G
Sbjct: 972 FG-SKSFDCEE-----SGQCWCQPG 990
>gi|116235485 delta-notch-like EGF repeat-containing transmembrane
[Homo sapiens]
Length = 737
Score = 36.2 bits (82), Expect = 0.16
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 22/90 (24%)
Query: 45 QPEKCDNNQYFDISALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICK-KCPEN 103
Q + C NN SC+ AN++QD +CVCLPG+ +C+ K
Sbjct: 354 QRKPCQNNA-------SCID--ANEKQDGSNFTCVCLPGY--------TGELCQSKIDYC 396
Query: 104 MKGVTEDGWNCISCPSDLTAEGKCHCPIGH 133
+ +G CIS S T C CP G+
Sbjct: 397 ILDPCRNGATCISSLSGFT----CQCPEGY 422
>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
Length = 1021
Score = 35.8 bits (81), Expect = 0.21
Identities = 35/138 (25%), Positives = 50/138 (36%), Gaps = 21/138 (15%)
Query: 62 CVPCGANQRQ-DARGTSCVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCISCPSD 120
C PC A + C CL GF S++ P C P S P +
Sbjct: 331 CSPCPARSHAPNPAAPVCPCLEGFYRASSDP-PEAPCTGPP--------------SAPQE 375
Query: 121 LTAEGKCHCPIGHILVERDINGT--LLSQATCELCDGNENSFMVVNALGDRCVRCEPTFV 178
L E + + H + R++ G LL C+ C+G + + G C RC
Sbjct: 376 LWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEP---ASGGGGTCHRCRDEVH 432
Query: 179 NTSRSCACSEPNILTGGL 196
R +E +L GGL
Sbjct: 433 FDPRQRGLTESRVLVGGL 450
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 35.0 bits (79), Expect = 0.35
Identities = 43/195 (22%), Positives = 69/195 (35%), Gaps = 39/195 (20%)
Query: 45 QPEKCDNNQYFDISALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPE-N 103
Q + C N ++ + +C C + GT C G Q I C KC E N
Sbjct: 776 QCDTCREN-FYGLDVTNCKACDCDTAGSLPGTVCNAKTG-QCICKPNVEGRQCNKCLEGN 833
Query: 104 MKGVTEDGWNCISCPSDLT-----------AEGKCHCPIG------HILVERDINGTLLS 146
+ + C+ C D T + G+C C +G + N T+ +
Sbjct: 834 FYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDN 893
Query: 147 QATCELCDGNE--------------NSFMVVNALGDRCVRCEPTF-VNTSRSCACSEPNI 191
C++C+ + V N G RC +C+P F ++ + C +
Sbjct: 894 FQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSC 953
Query: 192 LTGG----LCFSSTG 202
T G +C S TG
Sbjct: 954 HTTGAVNHICNSLTG 968
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 35.0 bits (79), Expect = 0.35
Identities = 43/195 (22%), Positives = 69/195 (35%), Gaps = 39/195 (20%)
Query: 45 QPEKCDNNQYFDISALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPE-N 103
Q + C N ++ + +C C + GT C G Q I C KC E N
Sbjct: 776 QCDTCREN-FYGLDVTNCKACDCDTAGSLPGTVCNAKTG-QCICKPNVEGRQCNKCLEGN 833
Query: 104 MKGVTEDGWNCISCPSDLT-----------AEGKCHCPIG------HILVERDINGTLLS 146
+ + C+ C D T + G+C C +G + N T+ +
Sbjct: 834 FYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDN 893
Query: 147 QATCELCDGNE--------------NSFMVVNALGDRCVRCEPTF-VNTSRSCACSEPNI 191
C++C+ + V N G RC +C+P F ++ + C +
Sbjct: 894 FQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSC 953
Query: 192 LTGG----LCFSSTG 202
T G +C S TG
Sbjct: 954 HTTGAVNHICNSLTG 968
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 34.3 bits (77), Expect = 0.60
Identities = 43/164 (26%), Positives = 55/164 (33%), Gaps = 35/164 (21%)
Query: 42 PFQQPEKCDNNQYFDISALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCP 101
P + KC NN +CV G SC C PGF + G C P
Sbjct: 1231 PVSRSPKCFNNG-------TCV-------DQVGGYSCTCPPGF-VGERCEGDVNECLSNP 1275
Query: 102 ENMKGVTEDGWNCISCPSDLTAEGKCHCPIGHI--LVERDING----TLLSQATCELCDG 155
+ +G NC+ +D C C GH E ING + TC +
Sbjct: 1276 CDARGTQ----NCVQRVNDF----HCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASN 1327
Query: 156 NENSFMVVNALGDRCVRCEPTFVNTSRSCACSEPNILTGGLCFS 199
F+ G CE N +R+ C L GG C S
Sbjct: 1328 TARGFICKCPAGFEGATCE----NDART--CGSLRCLNGGTCIS 1365
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 34.3 bits (77), Expect = 0.60
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 20/77 (25%)
Query: 65 CGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPEN--MKG-------VTEDGW--- 112
C G CVC PG++ GP +CP N ++G + +DG+
Sbjct: 161 CSGRGNFSTEGCGCVCEPGWK------GPNCSEPECPGNCHLRGRCIDGQCICDDGFTGE 214
Query: 113 NC--ISCPSDLTAEGKC 127
+C ++CPSD +GKC
Sbjct: 215 DCSQLACPSDCNDQGKC 231
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
sapiens]
Length = 986
Score = 34.3 bits (77), Expect = 0.60
Identities = 33/163 (20%), Positives = 54/163 (33%), Gaps = 34/163 (20%)
Query: 78 CVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCISCP--SDLTAEGKCHCPIGHIL 135
C+C GF+ + N +C+ CP + C CP S T+EG +C +
Sbjct: 254 CMCKAGFEAVENG----TVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGY 309
Query: 136 VERDIN------GTLLSQATCELCDGNENSFM-------------------VVNALGD-- 168
D++ T+ S + NE S M + + G
Sbjct: 310 YRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGR 369
Query: 169 -RCVRCEPTFVNTSRSCACSEPNILTGGLCFSSTGNFPLRRIS 210
C RC R +EP I L + F ++ ++
Sbjct: 370 GACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVN 412
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
sapiens]
Length = 987
Score = 34.3 bits (77), Expect = 0.60
Identities = 33/163 (20%), Positives = 54/163 (33%), Gaps = 34/163 (20%)
Query: 78 CVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCISCP--SDLTAEGKCHCPIGHIL 135
C+C GF+ + N +C+ CP + C CP S T+EG +C +
Sbjct: 254 CMCKAGFEAVENG----TVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGY 309
Query: 136 VERDIN------GTLLSQATCELCDGNENSFM-------------------VVNALGD-- 168
D++ T+ S + NE S M + + G
Sbjct: 310 YRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGR 369
Query: 169 -RCVRCEPTFVNTSRSCACSEPNILTGGLCFSSTGNFPLRRIS 210
C RC R +EP I L + F ++ ++
Sbjct: 370 GACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVN 412
>gi|61743978 stabilin 1 precursor [Homo sapiens]
Length = 2570
Score = 33.9 bits (76), Expect = 0.78
Identities = 36/156 (23%), Positives = 51/156 (32%), Gaps = 25/156 (16%)
Query: 65 CGANQRQDARGTSCVCLPGFQMISNN--------GGPAIICKKCPENMKGVTE------- 109
C N + A SC CLPG+ + P + +C + KG +
Sbjct: 204 CPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENY 263
Query: 110 --DGWNCISCPSDLTAEGKCHCPIGHILVERDINGTLLSQATCELCDGNENS----FMVV 163
DG C+ P D + CP L G L N N+ F
Sbjct: 264 HGDGMVCL--PKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFC 321
Query: 164 NALG-DRCVRCEPTFVNTSRSCACSEPNILTGGLCF 198
+ DR C+ T + SC C E + G C+
Sbjct: 322 SPFSCDRSATCQVT-ADGKTSCVCRESEVGDGRACY 356
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 33.9 bits (76), Expect = 0.78
Identities = 42/174 (24%), Positives = 54/174 (31%), Gaps = 35/174 (20%)
Query: 49 CDNNQYFDISALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPENMKG-- 106
CD D + P NQR CVC PG+ G + CP + +G
Sbjct: 390 CDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYT------GTDCGSRACPRDCRGRG 443
Query: 107 -------VTEDGWN-----CISCPSDLTAEGKCHCPIGHILVERDINGTLLSQATCE-LC 153
V G++ SCP D G+C G + G C C
Sbjct: 444 RCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCES--GRCMCWPGYTGRDCGTRACPGDC 501
Query: 154 DGNENSFMVVNALGDRCVRCEPTFVNT---SRSCA--CSEPNILTGGLCFSSTG 202
G + RCV C P F SR C C + G+C G
Sbjct: 502 RGRG------RCVDGRCV-CNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAG 548
Score = 32.7 bits (73), Expect = 1.7
Identities = 42/167 (25%), Positives = 59/167 (35%), Gaps = 36/167 (21%)
Query: 56 DISALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPE--NMKGVTEDGWN 113
D S SC P G +QR G CVC PG+ G + CP + +G E+G
Sbjct: 243 DCSQRSC-PRGCSQRGRCEGGRCVCDPGYT------GDDCGMRSCPRGCSQRGRCENG-R 294
Query: 114 CI-------------SCPSDLTAEGKCHCPIGHILVERDINGTLLSQATCELCDGNENSF 160
C+ SCP + G+ C G + + G +C G
Sbjct: 295 CVCNPGYTGEDCGVRSCPRGCSQRGR--CKDGRCVCDPGYTGEDCGTRSCPWDCGEGG-- 350
Query: 161 MVVNALGDRCVRCEPTFVN---TSRSCA--CSEPNILTGGLCFSSTG 202
+ RCV C P + ++R+C C G C TG
Sbjct: 351 ---RCVDGRCV-CWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTG 393
Score = 31.6 bits (70), Expect = 3.9
Identities = 39/147 (26%), Positives = 51/147 (34%), Gaps = 37/147 (25%)
Query: 61 SCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCISCPSD 120
SC +Q + RG CVC PG+ GP+ GW SCP D
Sbjct: 186 SCPDDCNDQGRCVRGR-CVCFPGYT------GPSC---------------GWP--SCPGD 221
Query: 121 LTAEGKCHCPIGHILVERDINGTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTFVNT 180
G+ C G + +G SQ +C G RCV C+P +
Sbjct: 222 CQGRGR--CVQGVCVCRAGFSGPDCSQRSCPRGCSQRG-----RCEGGRCV-CDPGYTGD 273
Query: 181 S---RSC--ACSEPNILTGGLCFSSTG 202
RSC CS+ G C + G
Sbjct: 274 DCGMRSCPRGCSQRGRCENGRCVCNPG 300
Score = 31.2 bits (69), Expect = 5.1
Identities = 25/94 (26%), Positives = 34/94 (36%), Gaps = 22/94 (23%)
Query: 49 CDNNQYFDISALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPE--NMKG 106
CD D + P G +QR CVC PG+ G + CP + +G
Sbjct: 266 CDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYT------GEDCGVRSCPRGCSQRG 319
Query: 107 VTEDGWNCI-------------SCPSDLTAEGKC 127
+DG C+ SCP D G+C
Sbjct: 320 RCKDG-RCVCDPGYTGEDCGTRSCPWDCGEGGRC 352
Score = 31.2 bits (69), Expect = 5.1
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 16/75 (21%)
Query: 61 SCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPENMKG---------VTEDG 111
S P G R+ R CVC+ GF+ GP + CP + +G V +DG
Sbjct: 686 SACPGGCGPRELCRAGQCVCVEGFR------GPDCAIQTCPGDCRGRGECHDGSCVCKDG 739
Query: 112 WNCISCPSDL-TAEG 125
+ C ++ T EG
Sbjct: 740 YAGEDCGEEVPTIEG 754
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,325,698
Number of Sequences: 37866
Number of extensions: 1513733
Number of successful extensions: 4561
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 4412
Number of HSP's gapped (non-prelim): 207
length of query: 995
length of database: 18,247,518
effective HSP length: 112
effective length of query: 883
effective length of database: 14,006,526
effective search space: 12367762458
effective search space used: 12367762458
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.