Search of human proteins with 18482385

Search of human proteins with 18482385

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18482385 solute carrier family 38, member 4 [Homo sapiens]
         (547 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|219689132 solute carrier family 38, member 4 [Homo sapiens]       1082   0.0  
gi|18482385 solute carrier family 38, member 4 [Homo sapiens]        1082   0.0  
gi|21361602 solute carrier family 38, member 2 [Homo sapiens]         596   e-170
gi|5870893 solute carrier family 38, member 3 [Homo sapiens]          501   e-142
gi|117168277 amino acid transporter system A1 [Homo sapiens]          469   e-132
gi|117168275 amino acid transporter system A1 [Homo sapiens]          469   e-132
gi|193788624 solute carrier family 38, member 5 [Homo sapiens]        424   e-118
gi|24429574 solute carrier family 38, member 6 [Homo sapiens]         375   e-104
gi|27735137 solute carrier family 38, member 11 [Homo sapiens]         79   8e-15
gi|83921602 solute carrier family 38, member 10 isoform a [Homo ...    72   2e-12
gi|20070376 solute carrier family 38, member 10 isoform b [Homo ...    72   2e-12
gi|122937281 solute carrier family 38, member 8 [Homo sapiens]         60   7e-09
gi|40807351 solute carrier family 36 (proton/amino acid symporte...    54   3e-07
gi|8922692 solute carrier family 38, member 7 [Homo sapiens]           53   6e-07
gi|41352721 solute carrier family 36 member 1 [Homo sapiens]           50   5e-06
gi|17999520 solute carrier family 32, member 1 [Homo sapiens]          45   1e-04
gi|222418631 solute carrier family 36, member 2 [Homo sapiens]         45   2e-04
gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo ...    44   3e-04
gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo ...    44   3e-04
gi|222418629 solute carrier family 38, member 9 [Homo sapiens]         38   0.021
gi|27262624 ATP-binding cassette, sub-family A , member 5 [Homo ...    34   0.30 
gi|27262626 ATP-binding cassette, sub-family A , member 5 [Homo ...    34   0.30 
gi|4758250 ephrin B2 [Homo sapiens]                                    33   0.51 
gi|149944536 ichthyin protein [Homo sapiens]                           33   0.67 
gi|162287219 prune homolog 2 [Homo sapiens]                            32   1.5  
gi|4885329 free fatty acid receptor 3 [Homo sapiens]                   32   2.0  
gi|9257240 neuroplastin isoform a precursor [Homo sapiens]             30   4.4  
gi|6912646 neuroplastin isoform b precursor [Homo sapiens]             30   4.4  
gi|40788011 claudin 8 [Homo sapiens]                                   30   4.4  
gi|4557457 nicotinic cholinergic receptor alpha 1 isoform b prec...    30   5.7  

>gi|219689132 solute carrier family 38, member 4 [Homo sapiens]
          Length = 547

 Score = 1082 bits (2797), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MDPMELRNVNIEPDDESSSGESAPDSYIGIGNSEKAAMSSQFANEDTESQKFLTNGFLGK 60
           MDPMELRNVNIEPDDESSSGESAPDSYIGIGNSEKAAMSSQFANEDTESQKFLTNGFLGK
Sbjct: 1   MDPMELRNVNIEPDDESSSGESAPDSYIGIGNSEKAAMSSQFANEDTESQKFLTNGFLGK 60

Query: 61  KKLADYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSL 120
           KKLADYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSL
Sbjct: 61  KKLADYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSL 120

Query: 121 YSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEV 180
           YSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEV
Sbjct: 121 YSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEV 180

Query: 181 IRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVV 240
           IRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVV
Sbjct: 181 IRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVV 240

Query: 241 IYKKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDEN 300
           IYKKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDEN
Sbjct: 241 IYKKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDEN 300

Query: 301 QAKGSLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRS 360
           QAKGSLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRS
Sbjct: 301 QAKGSLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRS 360

Query: 361 RRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVL 420
           RRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVL
Sbjct: 361 RRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVL 420

Query: 421 VAVTLTVPIVLFPIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGF 480
           VAVTLTVPIVLFPIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGF
Sbjct: 421 VAVTLTVPIVLFPIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGF 480

Query: 481 IGASSATMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDWIYD 540
           IGASSATMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDWIYD
Sbjct: 481 IGASSATMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDWIYD 540

Query: 541 PPNSKHH 547
           PPNSKHH
Sbjct: 541 PPNSKHH 547


>gi|18482385 solute carrier family 38, member 4 [Homo sapiens]
          Length = 547

 Score = 1082 bits (2797), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MDPMELRNVNIEPDDESSSGESAPDSYIGIGNSEKAAMSSQFANEDTESQKFLTNGFLGK 60
           MDPMELRNVNIEPDDESSSGESAPDSYIGIGNSEKAAMSSQFANEDTESQKFLTNGFLGK
Sbjct: 1   MDPMELRNVNIEPDDESSSGESAPDSYIGIGNSEKAAMSSQFANEDTESQKFLTNGFLGK 60

Query: 61  KKLADYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSL 120
           KKLADYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSL
Sbjct: 61  KKLADYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSL 120

Query: 121 YSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEV 180
           YSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEV
Sbjct: 121 YSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEV 180

Query: 181 IRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVV 240
           IRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVV
Sbjct: 181 IRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVV 240

Query: 241 IYKKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDEN 300
           IYKKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDEN
Sbjct: 241 IYKKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDEN 300

Query: 301 QAKGSLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRS 360
           QAKGSLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRS
Sbjct: 301 QAKGSLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRS 360

Query: 361 RRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVL 420
           RRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVL
Sbjct: 361 RRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVL 420

Query: 421 VAVTLTVPIVLFPIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGF 480
           VAVTLTVPIVLFPIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGF
Sbjct: 421 VAVTLTVPIVLFPIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGF 480

Query: 481 IGASSATMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDWIYD 540
           IGASSATMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDWIYD
Sbjct: 481 IGASSATMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDWIYD 540

Query: 541 PPNSKHH 547
           PPNSKHH
Sbjct: 541 PPNSKHH 547


>gi|21361602 solute carrier family 38, member 2 [Homo sapiens]
          Length = 506

 Score =  596 bits (1537), Expect = e-170
 Identities = 316/546 (57%), Positives = 383/546 (70%), Gaps = 40/546 (7%)

Query: 1   MDPMELRNVNIEPDDESSSGESAPDSYIGIGNSEKAAMSSQFANEDTESQKFLTNGFLGK 60
           M   E+   +I PD++SSS  S  D       +++AA+ S +A+ D E+Q FL    LGK
Sbjct: 1   MKKAEMGRFSISPDEDSSSYSSNSDFNYSYP-TKQAALKSHYADVDPENQNFLLESNLGK 59

Query: 61  KKLADYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSL 120
           KK   Y  E HPGTTSFGMS FNLSNAI+GSGILGLSYAMANTGI LFII+L  V+I SL
Sbjct: 60  KK---YETEFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSL 116

Query: 121 YSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEV 180
           YSVHLLLKTA EGGSL+YE+LG KAFG  GK+ A  SITMQNIGAMSSYLFI+KYELP V
Sbjct: 117 YSVHLLLKTANEGGSLLYEQLGYKAFGLVGKLAASGSITMQNIGAMSSYLFIVKYELPLV 176

Query: 181 IRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVV 240
           I+A   +E+ TG WYLNGNYL++ VS+ +ILPLSL +NLGYLGYTSG SL CMVFF+ VV
Sbjct: 177 IQALTNIEDKTGLWYLNGNYLVLLVSLVVILPLSLFRNLGYLGYTSGLSLLCMVFFLIVV 236

Query: 241 IYKKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDEN 300
           I KKFQ+PCP+      + N + N TL     ++P                         
Sbjct: 237 ICKKFQVPCPVEAA--LIINETINTTLTQPTALVP------------------------- 269

Query: 301 QAKGSLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRS 360
                     + +    +D C P YF+FNS+T YA+PIL+F+FVCHP VLPIY ELKDRS
Sbjct: 270 ---------ALSHNVTENDSCRPHYFIFNSQTVYAVPILIFSFVCHPAVLPIYEELKDRS 320

Query: 361 RRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVL 420
           RR+M  VS IS   M +MYLLAALFGYLTFY  VE ELLH YS +   DI LL+VRLAVL
Sbjct: 321 RRRMMNVSKISFFAMFLMYLLAALFGYLTFYEHVESELLHTYSSILGTDILLLIVRLAVL 380

Query: 421 VAVTLTVPIVLFPIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGF 480
           +AVTLTVP+V+FPIR+SV  LL   + FSW RH LI   ++A  N+LVI VPTI+ IFGF
Sbjct: 381 MAVTLTVPVVIFPIRSSVTHLLCASKDFSWWRHSLITVSILAFTNLLVIFVPTIRDIFGF 440

Query: 481 IGASSATMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDWIYD 540
           IGAS+A+MLIFILP+ FY+KLVKKE  +S QK+GAL FL+ G+  M GSMALI++DW+++
Sbjct: 441 IGASAASMLIFILPSAFYIKLVKKEPMKSVQKIGALFFLLSGVLVMTGSMALIVLDWVHN 500

Query: 541 PPNSKH 546
            P   H
Sbjct: 501 APGGGH 506


>gi|5870893 solute carrier family 38, member 3 [Homo sapiens]
          Length = 504

 Score =  501 bits (1289), Expect = e-142
 Identities = 265/467 (56%), Positives = 327/467 (70%), Gaps = 39/467 (8%)

Query: 73  GTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAKE 132
           G TSFGMS FNLSNAIMGSGILGL+YAMANTGIILF+ +L AVA+LS YS+HLLLK++  
Sbjct: 64  GKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGV 123

Query: 133 GGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTG 192
            G   YE+LG +AFG PGK+ A ++IT+QNIGAMSSYL+IIK ELP VI+ F+ LEE T 
Sbjct: 124 VGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTS 183

Query: 193 EWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLP 252
           +WY+NGNYL+I VSV IILPL+L++ LGYLGY+SGFSL+CMVFF+  VIYKKF +PCPLP
Sbjct: 184 DWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLP 243

Query: 253 VLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKGSLHDSGVE 312
                    +FNNT              S V  + +                      ++
Sbjct: 244 P--------NFNNT----------TGNFSHVEIVKEKVQ-------------------LQ 266

Query: 313 YEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISI 372
            E  +   C P YF  NS+TAY IPI+ FAFVCHPEVLPIY+ELKD S++KMQ +SN+SI
Sbjct: 267 VEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSI 326

Query: 373 TGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLF 432
             M +MY LAALFGYLTFY  VE ELLH YSKV   D+ +L VR+AVL AVTLTVPIVLF
Sbjct: 327 AVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLF 386

Query: 433 PIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFI 492
           P+R ++  +LFP + FSW+RH LIA  L+   N+LVI  P I  IFG IGA+SA  LIFI
Sbjct: 387 PVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIFI 446

Query: 493 LPAVFYLKLV--KKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDW 537
            PA+FY +++  +KE  RS  K+ AL F ++G   M  S++ IIIDW
Sbjct: 447 FPAIFYFRIMPTEKEPARSTPKILALCFAMLGFLLMTMSLSFIIIDW 493


>gi|117168277 amino acid transporter system A1 [Homo sapiens]
          Length = 487

 Score =  469 bits (1207), Expect = e-132
 Identities = 257/543 (47%), Positives = 349/543 (64%), Gaps = 67/543 (12%)

Query: 5   ELRNVNIEPDDESSSGESAPDSYIGIGNSEKAAMSSQFANEDTESQKFLTNGFLGKKKLA 64
           EL+N+ + P+D++ S +S   + +     E   ++S+F + D ES++ LTN  L KKK  
Sbjct: 12  ELQNMTV-PEDDNISNDSNDFTEV-----ENGQINSKFIS-DRESRRSLTNSHLEKKK-- 62

Query: 65  DYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVH 124
              DE+ PGTTS GMS FNLSNAIMGSGILGL++A+ANTGI+LF+++L +V +LS+YS++
Sbjct: 63  --CDEYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSIN 120

Query: 125 LLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAF 184
           LLL  +KE G ++YEKLGE+ FG  GK   F + ++QN GAM SYLFI+K ELP  I+  
Sbjct: 121 LLLICSKETGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFL 180

Query: 185 MGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKK 244
           MG EE    WY++G  L++ V+ GIILPL LLKNLGYLGYTSGFSL+CMVFF+ VVIYKK
Sbjct: 181 MGKEETFSAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKK 240

Query: 245 FQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKG 304
           FQIPC +P L+ ++                  NS ++D                      
Sbjct: 241 FQIPCIVPELNSTIS----------------ANSTNADT--------------------- 263

Query: 305 SLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKM 364
                           C PKY  FNS+T YA+P + FAFVCHP VLPIYSELKDRS++KM
Sbjct: 264 ----------------CTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKM 307

Query: 365 QTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVT 424
           Q VSNIS   M VMY L A+FGYLTFY  V+ +LLH Y      DI +L VRLAV+VAV 
Sbjct: 308 QMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQS--KDDILILTVRLAVIVAVI 365

Query: 425 LTVPIVLFPIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGAS 484
           LTVP++ F +R+S+  L   K  F+  RH ++  +L+ + N+LVI +P++K IFG +G +
Sbjct: 366 LTVPVLFFTVRSSLFELA-KKTKFNLCRHTVVTCILLVVINLLVIFIPSMKDIFGVVGVT 424

Query: 485 SATMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDWIYDPPNS 544
           SA MLIFILP+  YLK+  ++  +  Q++ A +FL +G+ F + S+ L+I DW     + 
Sbjct: 425 SANMLIFILPSSLYLKITDQDGDKGTQRIWAALFLGLGVLFSLVSIPLVIYDWACSSSSD 484

Query: 545 KHH 547
           + H
Sbjct: 485 EGH 487


>gi|117168275 amino acid transporter system A1 [Homo sapiens]
          Length = 487

 Score =  469 bits (1207), Expect = e-132
 Identities = 257/543 (47%), Positives = 349/543 (64%), Gaps = 67/543 (12%)

Query: 5   ELRNVNIEPDDESSSGESAPDSYIGIGNSEKAAMSSQFANEDTESQKFLTNGFLGKKKLA 64
           EL+N+ + P+D++ S +S   + +     E   ++S+F + D ES++ LTN  L KKK  
Sbjct: 12  ELQNMTV-PEDDNISNDSNDFTEV-----ENGQINSKFIS-DRESRRSLTNSHLEKKK-- 62

Query: 65  DYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVH 124
              DE+ PGTTS GMS FNLSNAIMGSGILGL++A+ANTGI+LF+++L +V +LS+YS++
Sbjct: 63  --CDEYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSIN 120

Query: 125 LLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAF 184
           LLL  +KE G ++YEKLGE+ FG  GK   F + ++QN GAM SYLFI+K ELP  I+  
Sbjct: 121 LLLICSKETGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFL 180

Query: 185 MGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKK 244
           MG EE    WY++G  L++ V+ GIILPL LLKNLGYLGYTSGFSL+CMVFF+ VVIYKK
Sbjct: 181 MGKEETFSAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKK 240

Query: 245 FQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKG 304
           FQIPC +P L+ ++                  NS ++D                      
Sbjct: 241 FQIPCIVPELNSTIS----------------ANSTNADT--------------------- 263

Query: 305 SLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKM 364
                           C PKY  FNS+T YA+P + FAFVCHP VLPIYSELKDRS++KM
Sbjct: 264 ----------------CTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKM 307

Query: 365 QTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVT 424
           Q VSNIS   M VMY L A+FGYLTFY  V+ +LLH Y      DI +L VRLAV+VAV 
Sbjct: 308 QMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQS--KDDILILTVRLAVIVAVI 365

Query: 425 LTVPIVLFPIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGAS 484
           LTVP++ F +R+S+  L   K  F+  RH ++  +L+ + N+LVI +P++K IFG +G +
Sbjct: 366 LTVPVLFFTVRSSLFELA-KKTKFNLCRHTVVTCILLVVINLLVIFIPSMKDIFGVVGVT 424

Query: 485 SATMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDWIYDPPNS 544
           SA MLIFILP+  YLK+  ++  +  Q++ A +FL +G+ F + S+ L+I DW     + 
Sbjct: 425 SANMLIFILPSSLYLKITDQDGDKGTQRIWAALFLGLGVLFSLVSIPLVIYDWACSSSSD 484

Query: 545 KHH 547
           + H
Sbjct: 485 EGH 487


>gi|193788624 solute carrier family 38, member 5 [Homo sapiens]
          Length = 472

 Score =  424 bits (1089), Expect = e-118
 Identities = 240/467 (51%), Positives = 306/467 (65%), Gaps = 52/467 (11%)

Query: 73  GTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAKE 132
           G TSFGMS FNLSNAIMGSGILGL+YAMA+TG+I F+ +LL +A+LS YS+HLLL  A  
Sbjct: 46  GKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGI 105

Query: 133 GGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTG 192
            G   YE+LG++AFG  GK+     I + N+GAMSSYLFIIK ELP VI  F+ ++   G
Sbjct: 106 AGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPE-G 164

Query: 193 EWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLP 252
           +W+L GN LII VSV IILPL+L+K+LGYLGYTSG SLTCM+FF+  VIYKKFQ+ C + 
Sbjct: 165 DWFLKGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIG 224

Query: 253 VLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKGSLHDSGVE 312
                      +N   M                             E++A   L   G+ 
Sbjct: 225 -----------HNETAM-----------------------------ESEALVGLPSQGL- 243

Query: 313 YEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISI 372
                +  CE + F  +S+ +Y +PI+ FAFVCHPEVLPIY+EL   S+R+MQ V+N+SI
Sbjct: 244 -----NSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSI 298

Query: 373 TGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLF 432
             M  MY L A FGYLTFY  V+ E+LH YS+   L   +L VRLAVL+AVTLTVP+VLF
Sbjct: 299 GAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPL---ILCVRLAVLLAVTLTVPVVLF 355

Query: 433 PIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFI 492
           PIR ++  LLFP + FSW RH  IA +L+ L NVLVI VPTI+ IFG IG++SA  LIFI
Sbjct: 356 PIRRALQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFI 415

Query: 493 LPAVFYLKLVKKET--FRSPQKVGALIFLVVGIFFMIGSMALIIIDW 537
           LP++FYL++V  E   F S  K+ AL F V+G+ FM  S+  +  +W
Sbjct: 416 LPSIFYLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANW 462


>gi|24429574 solute carrier family 38, member 6 [Homo sapiens]
          Length = 456

 Score =  375 bits (963), Expect = e-104
 Identities = 214/474 (45%), Positives = 285/474 (60%), Gaps = 63/474 (13%)

Query: 69  EHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLK 128
           +  PG  SFG+S FNL NAIMGSGILGL+Y MANTG+  F  +LL VA+L+ YSVHLLL 
Sbjct: 40  QRSPGV-SFGLSVFNLMNAIMGSGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLS 98

Query: 129 TAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLE 188
              +     YE LG  AFG PGK+    +I +QNIGAMSSYL IIK ELP  I  F+   
Sbjct: 99  MCIQTAVTSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFL--- 155

Query: 189 ENTGE----WYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKK 244
             TG+    WYL+G  L+I + VGI+ PL+LL  +G+LGYTS  S   M+FF  VVI KK
Sbjct: 156 --TGDYSRYWYLDGQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKK 213

Query: 245 FQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKG 304
           + IPCPL +                              N++                  
Sbjct: 214 WSIPCPLTL------------------------------NYV------------------ 225

Query: 305 SLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKM 364
              + G +    +DD C+PK F F+  +AYA+P + F+F+CH  +LPIY EL+  S+++M
Sbjct: 226 ---EKGFQISNVTDD-CKPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRM 281

Query: 365 QTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVT 424
           Q V+N +I    ++Y ++ALFGYLTFY +VE ELL  YSK  + D+ ++ V+L +L AV 
Sbjct: 282 QNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVL 341

Query: 425 LTVPIVLFPIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGAS 484
           LTVP++ FP R +V  + F   PFSWIRHFLI   L  +  +L I VP I+ +FG +GAS
Sbjct: 342 LTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGAS 401

Query: 485 SATMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDWI 538
           ++T LIFI P +FYLKL  +E F S +K+GA + L+ GI     S+ALII DWI
Sbjct: 402 TSTCLIFIFPGLFYLKL-SREDFLSWKKLGAFVLLIFGILVGNFSLALIIFDWI 454


>gi|27735137 solute carrier family 38, member 11 [Homo sapiens]
          Length = 384

 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 57/215 (26%), Positives = 100/215 (46%), Gaps = 5/215 (2%)

Query: 320 KCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMY 379
           K E  +         A+ ++ FAF+CH     +YS L++ +  K   + ++SI   + + 
Sbjct: 130 KTEDAWVFAKPNAIQAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFIC 189

Query: 380 LLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSVI 439
           +  A  GYLTF G  + +L   Y +    D  +   R    V V LT P+  F  R  VI
Sbjct: 190 IFFATCGYLTFTGFTQGDLFENYCR---NDDLVTFGRFCYGVTVILTYPMECFVTR-EVI 245

Query: 440 TLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYL 499
             +F     S + H ++  ++I +  ++ +L+  +  +    G   AT LIFI+P+  YL
Sbjct: 246 ANVFFGGNLSSVFHIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYL 305

Query: 500 KLVKKETFRSPQKVGALIFLVVGIFFMIGSMALII 534
           KL ++    S  K+ + + L +G   M+    + I
Sbjct: 306 KLSEEPRTHS-DKIMSCVMLPIGAVVMVFGFVMAI 339



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 36/153 (23%), Positives = 68/153 (44%), Gaps = 24/153 (15%)

Query: 100 MANTGIILFIIMLLAVAILSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFVSIT 159
           M   G  L I++L  V+ ++ +S+ LL+K     G+  Y+ L  K FG+PG +       
Sbjct: 1   MKQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYL------- 53

Query: 160 MQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNL 219
                     L ++++  P ++       EN    ++  +++I   +V   LPLSL +N+
Sbjct: 54  ---------LLSVLQFLYPFIVD-----PENV---FIGRHFIIGLSTVTFTLPLSLYRNI 96

Query: 220 GYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLP 252
             LG  S  S       + +V+ +   +   +P
Sbjct: 97  AKLGKVSLISTGLTTLILGIVMARAISLGPHIP 129


>gi|83921602 solute carrier family 38, member 10 isoform a [Homo
           sapiens]
          Length = 1119

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 47/179 (26%), Positives = 88/179 (49%), Gaps = 16/179 (8%)

Query: 336 IPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTF-YGEV 394
           IPI   +F C  +VLP Y  L + S + M ++   S+  +   Y++   FGY++F     
Sbjct: 198 IPIFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATA 257

Query: 395 EDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRP------- 447
            + L+H  S + T      M+R+  +++V +  P+++ P R ++ TLL  ++        
Sbjct: 258 GNVLMHFPSNLVT-----EMLRVGFMMSVAVGFPMMILPCRQALSTLLCEQQQKDGTFAA 312

Query: 448 ---FSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVK 503
                 +R   +   ++    V  IL+P ++ I G  GA+  +++ FI PA+ Y K+ K
Sbjct: 313 GGYMPPLRFKALTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKIHK 371



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 37/154 (24%), Positives = 72/154 (46%), Gaps = 6/154 (3%)

Query: 83  NLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAKEGGSLIYEKLG 142
           N+ N+I+G  +L + +     GI+L  ++L+  + ++  S   L+K+A       Y  L 
Sbjct: 14  NIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLA 73

Query: 143 EKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLI 202
             A+G  GK+    S+    +G   ++  +I            G +   G + +   +L+
Sbjct: 74  FHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQVG-GTFRM---FLL 129

Query: 203 IFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFF 236
             VS+ I+LPLSL +N+  +     FS   ++F+
Sbjct: 130 FAVSLCIVLPLSLQRNM--MASIQSFSAMALLFY 161


>gi|20070376 solute carrier family 38, member 10 isoform b [Homo
           sapiens]
          Length = 780

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 47/179 (26%), Positives = 88/179 (49%), Gaps = 16/179 (8%)

Query: 336 IPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTF-YGEV 394
           IPI   +F C  +VLP Y  L + S + M ++   S+  +   Y++   FGY++F     
Sbjct: 198 IPIFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATA 257

Query: 395 EDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRP------- 447
            + L+H  S + T      M+R+  +++V +  P+++ P R ++ TLL  ++        
Sbjct: 258 GNVLMHFPSNLVT-----EMLRVGFMMSVAVGFPMMILPCRQALSTLLCEQQQKDGTFAA 312

Query: 448 ---FSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVK 503
                 +R   +   ++    V  IL+P ++ I G  GA+  +++ FI PA+ Y K+ K
Sbjct: 313 GGYMPPLRFKALTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKIHK 371



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 37/154 (24%), Positives = 72/154 (46%), Gaps = 6/154 (3%)

Query: 83  NLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAKEGGSLIYEKLG 142
           N+ N+I+G  +L + +     GI+L  ++L+  + ++  S   L+K+A       Y  L 
Sbjct: 14  NIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLA 73

Query: 143 EKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLI 202
             A+G  GK+    S+    +G   ++  +I            G +   G + +   +L+
Sbjct: 74  FHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQVG-GTFRM---FLL 129

Query: 203 IFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFF 236
             VS+ I+LPLSL +N+  +     FS   ++F+
Sbjct: 130 FAVSLCIVLPLSLQRNM--MASIQSFSAMALLFY 161


>gi|122937281 solute carrier family 38, member 8 [Homo sapiens]
          Length = 435

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 51/215 (23%), Positives = 94/215 (43%), Gaps = 23/215 (10%)

Query: 337 PILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVED 396
           P + F F CH   + IY  ++ RS      VS +S+    ++Y L  ++G+LTF  EV  
Sbjct: 223 PTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSA 282

Query: 397 ELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRPFS------- 449
           ++L +Y      D+ +++ R+   V++    PIVLF +  SV+   + +           
Sbjct: 283 DVLMSYP---GNDMVIIVARVLFAVSIVTVYPIVLF-LGRSVMQDFWRRSCLGGWGPSAL 338

Query: 450 ------WIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVK 503
                 W+R   +  + + +   + + +P +  I   IG  S +  IFI P +  +  + 
Sbjct: 339 ADPSGLWVR-MPLTILWVTVTLAMALFMPDLSEIVSIIGGIS-SFFIFIFPGLCLICAMG 396

Query: 504 KETFRSPQK----VGALIFLVVGIFFMIGSMALII 534
            E      K    V  ++ ++VG F    S A  +
Sbjct: 397 VEPIGPRVKCCLEVWGVVSVLVGTFIFGQSTAAAV 431



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 44/184 (23%), Positives = 86/184 (46%), Gaps = 10/184 (5%)

Query: 68  DEHHPGTTSFGMSS----FNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSV 123
           ++ HP T +  +SS    F L  + +G+G+L   +A +  G ++   ++  V+++ L S 
Sbjct: 13  EKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISG 72

Query: 124 HLLLK-TAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMS-SYLFIIKYELPEVI 181
            ++L   A   G   Y+ +     G P       +  + N+  +S ++L +I  +L ++ 
Sbjct: 73  LVILGYAAAVSGQATYQGVVRGLCG-PAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLC 131

Query: 182 RAFM-GLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTS--GFSLTCMVFFVS 238
            + + G       WY +  + +  +SV +ILPLS  + + +  YTS  G    C +  V 
Sbjct: 132 DSLLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVI 191

Query: 239 VVIY 242
            V Y
Sbjct: 192 TVQY 195


>gi|40807351 solute carrier family 36 (proton/amino acid symporter),
           member 4 [Homo sapiens]
          Length = 504

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 49/210 (23%), Positives = 94/210 (44%), Gaps = 17/210 (8%)

Query: 340 VFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELL 399
           VFAF     VLP+ +++K+ S+R  Q + NI +  +  +Y+  A  GY+ F+ E++  + 
Sbjct: 281 VFAFEGIGVVLPLENQMKE-SKRFPQAL-NIGMGIVTTLYVTLATLGYMCFHDEIKGSI- 337

Query: 400 HAYSKVYTLDIP-----LLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRPFSW--IR 452
                  TL++P        V++     + +T  I  +     +I  +  K    W  I 
Sbjct: 338 -------TLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIPGITSKFHTKWKQIC 390

Query: 453 HFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKETFRSPQK 512
            F I + L+++     IL+P +  +  F+GA S++ L  ILP +  +    KE +     
Sbjct: 391 EFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLALILPPLVEILTFSKEHYNIWMV 450

Query: 513 VGALIFLVVGIFFMIGSMALIIIDWIYDPP 542
           +  +     G+   +    + + + IY  P
Sbjct: 451 LKNISIAFTGVVGFLLGTYITVEEIIYPTP 480



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 44/209 (21%), Positives = 88/209 (42%), Gaps = 31/209 (14%)

Query: 76  SFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAK---- 131
           SF  +  +L    +G+G+LGL  A+ N GI+L  I L+ + I+S++ +H+L++ +     
Sbjct: 60  SFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCL 119

Query: 132 --EGGSLIYE------------KLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYEL 177
             +  +L Y                +K   W   +  F  +  Q +G  S Y+  +   +
Sbjct: 120 RFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQ-LGFCSVYIVFLAENV 178

Query: 178 PEVIRAFMGLEENTGEWYLNGN-----------YLIIFVSVGIILP-LSLLKNLGYLGYT 225
            +V   F+  +        + N           Y++ F+   I+L  +  LKNL  L + 
Sbjct: 179 KQVHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFL 238

Query: 226 SGFSLTCMVFFVSVVIYKKFQIPCPLPVL 254
           +  S+   +  +   + +    P  LP++
Sbjct: 239 ANVSMAVSLVIIYQYVVRNMPDPHNLPIV 267


>gi|8922692 solute carrier family 38, member 7 [Homo sapiens]
          Length = 462

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 40/173 (23%), Positives = 79/173 (45%), Gaps = 2/173 (1%)

Query: 73  GTTSFGMSSFNLSNAIMGSGILGLSYAMANTG-IILFIIMLLAVAILSLYSVHLLLKTAK 131
           GTTS   + F + NA +G+G+L    A +  G +   I + + + +  +  + +L   ++
Sbjct: 49  GTTSTLGAIFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQ 108

Query: 132 EGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEEN- 190
                 Y+++     G    +   V+I +   G   ++L II  +  ++I       E  
Sbjct: 109 ASNERTYQEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGA 168

Query: 191 TGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYK 243
           +G WY +  + I   +   ILPLS+ + +G+  Y S  S+    +  ++VI K
Sbjct: 169 SGPWYTDRKFTISLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIK 221



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 40/170 (23%), Positives = 78/170 (45%), Gaps = 12/170 (7%)

Query: 335 AIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEV 394
           A+P + F F CH   +P+++ ++    +    V   ++   L +Y+   + G+LTF   V
Sbjct: 247 AMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAV 306

Query: 395 EDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSV--ITLLFPKRPF---- 448
           + ++L +Y    + D+ + + R  ++++V  + PI+ F  R  V  + L +   P     
Sbjct: 307 DPDVLLSYP---SEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPVEEDV 363

Query: 449 --SWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAV 496
                R  L   V   L  +L + +P I  +   IG  +A   IF+ P +
Sbjct: 364 GRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAA-CFIFVFPGL 412


>gi|41352721 solute carrier family 36 member 1 [Homo sapiens]
          Length = 476

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 42/198 (21%), Positives = 88/198 (44%), Gaps = 19/198 (9%)

Query: 340 VFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELL 399
           +F+F     VLP+ +++KD   RK   +  + +  + ++Y+     GYL F   ++  + 
Sbjct: 266 IFSFEGIGMVLPLENKMKDP--RKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSI- 322

Query: 400 HAYSKVYTLDIP----LLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRP--FSWIRH 453
                  TL++P       V+L   + +  T  +  +     +I     + P     +  
Sbjct: 323 -------TLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVSRAPEHCELVVD 375

Query: 454 FLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKETFRSPQKV 513
             +  VL+ L  +L IL+P +  +   +G+ S++ L  I+P +  +     E   SP  +
Sbjct: 376 LFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGM-SPLTI 434

Query: 514 --GALIFLVVGIFFMIGS 529
              ALI ++  + F++G+
Sbjct: 435 FKDALISILGFVGFVVGT 452



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 21/89 (23%), Positives = 46/89 (51%)

Query: 42  FANEDTESQKFLTNGFLGKKKLADYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMA 101
           +++ D   ++  + G         Y       +T++  +  +L    +G+G+LGL  A+ 
Sbjct: 14  YSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVK 73

Query: 102 NTGIILFIIMLLAVAILSLYSVHLLLKTA 130
           N GI++  I LL + I++++ + +L+K A
Sbjct: 74  NAGIVMGPISLLIIGIVAVHCMGILVKCA 102


>gi|17999520 solute carrier family 32, member 1 [Homo sapiens]
          Length = 525

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 52/237 (21%), Positives = 107/237 (45%), Gaps = 38/237 (16%)

Query: 80  SSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLL---LKTAKEGGSL 136
           + +N++NAI G  +LGL YA+ + G  L + +++  A++  Y+  +L   L    E G +
Sbjct: 121 AGWNVTNAIQGMFVLGLPYAILHGG-YLGLFLIIFAAVVCCYTGKILIACLYEENEDGEV 179

Query: 137 IYEKLGEKAFG-------WPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEE 189
           +  +    A         +P   G  V++  Q I  + + +  +      +  +F GL  
Sbjct: 180 VRVRDSYVAIANACCAPRFPTLGGRVVNVA-QIIELVMTCILYVVVSGNLMYNSFPGLPV 238

Query: 190 NTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMV--FFVSVVI------ 241
           +   W +        ++  ++LP + LKNL  +   S FSL C +  F +++++      
Sbjct: 239 SQKSWSI--------IATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINILVIAYCLS 287

Query: 242 ------YKKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNN-SESSDVNFMMDYTH 291
                 ++K +    +     S+G + F+ T  + +  L  N  + S+ + MM++TH
Sbjct: 288 RARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTH 344



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 45/222 (20%), Positives = 92/222 (41%), Gaps = 29/222 (13%)

Query: 324 KYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAA 383
           K+++   +   +I I+VF++     +  +   ++  S  +   + N +     V+  L A
Sbjct: 298 KFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPS--EFHCMMNWTHIAACVLKGLFA 355

Query: 384 LFGYLTFYGEVEDELLHAYSKVYTLDIP---LLMVRLAVLVAVTLTVPIVLFPIRTSVIT 440
           L  YLT+  E ++        V T ++P     +V + ++    L+ P+  F     +  
Sbjct: 356 LVAYLTWADETKE--------VITDNLPGSIRAVVNIFLVAKALLSYPLPFFAAVEVLEK 407

Query: 441 LLFPK--------------RPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSA 486
            LF +              R  SW     +   L+    ++ I VP    + G  G+ + 
Sbjct: 408 SLFQEGSRAFFPACYSGDGRLKSW--GLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTG 465

Query: 487 TMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIG 528
             L F+LP++F+L+L+ ++           IF++ GI  + G
Sbjct: 466 AGLCFLLPSLFHLRLLWRKLLWHQVFFDVAIFVIGGICSVSG 507


>gi|222418631 solute carrier family 36, member 2 [Homo sapiens]
          Length = 483

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 41/198 (20%), Positives = 88/198 (44%), Gaps = 19/198 (9%)

Query: 340 VFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELL 399
           +F+F     VLP+ +++K+   R    + ++ ++ +  +Y+  A  GYL F  +++  + 
Sbjct: 273 IFSFESIGVVLPLENKMKNA--RHFPAILSLGMSIVTSLYIGMAALGYLRFGDDIKASI- 329

Query: 400 HAYSKVYTLDIP----LLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRPFSWIR--H 453
                  +L++P       V+L  +  +  T  +  +     +I     +    W     
Sbjct: 330 -------SLNLPNCWLYQSVKLLYIAGILCTYALQFYVPAEIIIPFAISRVSTRWALPLD 382

Query: 454 FLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKETFRSPQKV 513
             I  V++ L  +L IL+P +  +   +G+ S T L  I+P +  +     E   SP  +
Sbjct: 383 LSIRLVMVCLTCLLAILIPRLDLVISLVGSVSGTALALIIPPLLEVTTFYSEGM-SPLTI 441

Query: 514 --GALIFLVVGIFFMIGS 529
              ALI ++  + F++G+
Sbjct: 442 FKDALISILGFVGFVVGT 459



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 49/209 (23%), Positives = 88/209 (42%), Gaps = 39/209 (18%)

Query: 73  GTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAK- 131
           G T F  +  +L    MG+GILGL  A+ N GI++  + LL +  ++ + +H+L+K A+ 
Sbjct: 53  GITVF-QALIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHILVKCAQR 111

Query: 132 ----------EGGSLIYEKLGEKAFGWPGK--------IGAFVSITMQNIGAMSSYLFII 173
                     + G  +   L      W           +  F+ IT   +G    Y+  +
Sbjct: 112 FCKRLNKPFMDYGDTVMHGLEANPNAWLQNHAHWGRHIVSFFLIIT--QLGFCCVYIVFL 169

Query: 174 KYELPEVIRAFMGLEENTGEWYLNGN-----------YLIIFVSVGIILPLSLLKNLGYL 222
              L +V+ A   +   T   Y N             Y++ F+    ++ L L++NL  L
Sbjct: 170 ADNLKQVVEA---VNSTTNNCYSNETVILTPTMDSRLYMLSFLP--FLVLLVLIRNLRIL 224

Query: 223 GYTSGF-SLTCMVFFVSVVIYKKFQIPCP 250
              S   +++ +V  V ++ Y   +IP P
Sbjct: 225 TIFSMLANISMLVSLVIIIQYITQEIPDP 253


>gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo
           sapiens]
          Length = 511

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 37/190 (19%), Positives = 79/190 (41%), Gaps = 16/190 (8%)

Query: 340 VFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELL 399
           +F F     VLP+ +++K   +        +SI  ++++Y+L    GY+ F  + +  + 
Sbjct: 302 IFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSI--VIILYILLGTLGYMKFGSDTQASI- 358

Query: 400 HAYSKVYTLDIP----LLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRPFSWIRH-- 453
                  TL++P       V+L   + +  T  +        +I     +   SW     
Sbjct: 359 -------TLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVSESWALFVD 411

Query: 454 FLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKETFRSPQKV 513
             + + L+ L  V  IL+P +  +   +G+ S++ L  I+PA+  + +   E        
Sbjct: 412 LSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIA 471

Query: 514 GALIFLVVGI 523
             ++  +VG+
Sbjct: 472 KDIMISIVGL 481



 Score = 36.6 bits (83), Expect = 0.061
 Identities = 19/64 (29%), Positives = 36/64 (56%), Gaps = 2/64 (3%)

Query: 70  HHPGTTSFGMSS--FNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLL 127
           H  G     M     +L    +G+G+LGL  A+ N G+++  + LLA+ +L+++ + +LL
Sbjct: 35  HPAGEAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILL 94

Query: 128 KTAK 131
             A+
Sbjct: 95  NCAQ 98


>gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo
           sapiens]
          Length = 470

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 37/190 (19%), Positives = 79/190 (41%), Gaps = 16/190 (8%)

Query: 340 VFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELL 399
           +F F     VLP+ +++K   +        +SI  ++++Y+L    GY+ F  + +  + 
Sbjct: 261 IFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSI--VIILYILLGTLGYMKFGSDTQASI- 317

Query: 400 HAYSKVYTLDIP----LLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRPFSWIRH-- 453
                  TL++P       V+L   + +  T  +        +I     +   SW     
Sbjct: 318 -------TLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVSESWALFVD 370

Query: 454 FLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKETFRSPQKV 513
             + + L+ L  V  IL+P +  +   +G+ S++ L  I+PA+  + +   E        
Sbjct: 371 LSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIA 430

Query: 514 GALIFLVVGI 523
             ++  +VG+
Sbjct: 431 KDIMISIVGL 440



 Score = 36.6 bits (83), Expect = 0.061
 Identities = 19/64 (29%), Positives = 36/64 (56%), Gaps = 2/64 (3%)

Query: 70  HHPGTTSFGMSS--FNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLL 127
           H  G     M     +L    +G+G+LGL  A+ N G+++  + LLA+ +L+++ + +LL
Sbjct: 35  HPAGEAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILL 94

Query: 128 KTAK 131
             A+
Sbjct: 95  NCAQ 98


>gi|222418629 solute carrier family 38, member 9 [Homo sapiens]
          Length = 561

 Score = 38.1 bits (87), Expect = 0.021
 Identities = 36/199 (18%), Positives = 84/199 (42%), Gaps = 16/199 (8%)

Query: 338 ILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVM--YLLAALFGYLTFYGE-- 393
           +L  AF  H  ++ +       ++++   V ++ I  MLV   YL   +  + +F     
Sbjct: 365 VLTLAFFIHNCIITLLKN----NKKQENNVRDLCIAYMLVTLTYLYIGVLVFASFPSPPL 420

Query: 394 ----VEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRPFS 449
               +E   L  +    TL     + R+ +L  +    P++ +  R  ++  +F     S
Sbjct: 421 SKDCIEQNFLDNFPSSDTLSF---IARIFLLFQMMTVYPLLGYLARVQLLGHIFGDIYPS 477

Query: 450 WIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFY-LKLVKKETFR 508
                ++  +++    ++    P I  I  + GA+     +FI P++ Y + L ++E   
Sbjct: 478 IFHVLILNLIIVGAGVIMACFYPNIGGIIRYSGAACGLAFVFIYPSLIYIISLHQEERLT 537

Query: 509 SPQKVGALIFLVVGIFFMI 527
            P+ +  +  +++G+  +I
Sbjct: 538 WPKLIFHVFIIILGVANLI 556



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 25/113 (22%), Positives = 54/113 (47%), Gaps = 7/113 (6%)

Query: 62  KLADYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLY 121
           KL  Y + +   T+   ++ F + N +MG+ IL + + +   G    + +++ + +L+LY
Sbjct: 106 KLQSYTEGYGKNTSL--VTIFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIILMGLLTLY 163

Query: 122 SVHLLLKT-----AKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSY 169
             + ++K+     + +  S  Y  +    FG  G+  + +   +  IGAM  Y
Sbjct: 164 CCYRVVKSRTMMFSLDTTSWEYPDVCRHYFGSFGQWSSLLFSLVSLIGAMIVY 216


>gi|27262624 ATP-binding cassette, sub-family A , member 5 [Homo
           sapiens]
          Length = 1642

 Score = 34.3 bits (77), Expect = 0.30
 Identities = 36/164 (21%), Positives = 65/164 (39%), Gaps = 44/164 (26%)

Query: 418 AVLVAVTLTVPIVLFPIRTSVITLLFPKRPFS---------------------------- 449
           AV++  T  V I  FP    +I L+    PF                             
Sbjct: 202 AVIMGETAVVEIDTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKKIKEFLKIMGLHDTA 261

Query: 450 -WIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVF-----YLKLVK 503
            W+   L+   LI L ++L+ ++ T   +F      S++++IF+L  ++     +  L+ 
Sbjct: 262 FWLSWVLLYTSLIFLMSLLMAVIATASLLF----PQSSSIVIFLLFFLYGLSSVFFALML 317

Query: 504 KETFRSPQKVGALIFLVVGIFFMIGSMALII------IDWIYDP 541
              F+  + VG + F V   F  IG M ++I      + W++ P
Sbjct: 318 TPLFKKSKHVGIVEFFVTVAFGFIGLMIILIESFPKSLVWLFSP 361


>gi|27262626 ATP-binding cassette, sub-family A , member 5 [Homo
           sapiens]
          Length = 1642

 Score = 34.3 bits (77), Expect = 0.30
 Identities = 36/164 (21%), Positives = 65/164 (39%), Gaps = 44/164 (26%)

Query: 418 AVLVAVTLTVPIVLFPIRTSVITLLFPKRPFS---------------------------- 449
           AV++  T  V I  FP    +I L+    PF                             
Sbjct: 202 AVIMGETAVVEIDTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKKIKEFLKIMGLHDTA 261

Query: 450 -WIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVF-----YLKLVK 503
            W+   L+   LI L ++L+ ++ T   +F      S++++IF+L  ++     +  L+ 
Sbjct: 262 FWLSWVLLYTSLIFLMSLLMAVIATASLLF----PQSSSIVIFLLFFLYGLSSVFFALML 317

Query: 504 KETFRSPQKVGALIFLVVGIFFMIGSMALII------IDWIYDP 541
              F+  + VG + F V   F  IG M ++I      + W++ P
Sbjct: 318 TPLFKKSKHVGIVEFFVTVAFGFIGLMIILIESFPKSLVWLFSP 361


>gi|4758250 ephrin B2 [Homo sapiens]
          Length = 333

 Score = 33.5 bits (75), Expect = 0.51
 Identities = 21/87 (24%), Positives = 45/87 (51%), Gaps = 2/87 (2%)

Query: 34  EKAAMSSQFANEDTESQKFLTNGFLGKKKLADYADEHHPGTTSFGMSSFNLSNAIMGSGI 93
           + A+ +    N+D   +  L  G  G+        + +PG+++ G S+ +  N I+GS +
Sbjct: 166 QDASSAGSTRNKDPTRRPELEAGTNGRSSTTSPFVKPNPGSSTDGNSAGHSGNNILGSEV 225

Query: 94  LGLSYAMANTGIILFIIMLLAVAILSL 120
               +A   +G I+FI++++ + +L L
Sbjct: 226 --ALFAGIASGCIIFIVIIITLVVLLL 250


>gi|149944536 ichthyin protein [Homo sapiens]
          Length = 466

 Score = 33.1 bits (74), Expect = 0.67
 Identities = 51/249 (20%), Positives = 109/249 (43%), Gaps = 40/249 (16%)

Query: 93  ILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKI 152
           I+ ++  M +TG I+F ++LL   ++ ++   ++     +   LIY  +          I
Sbjct: 247 IMEMASKMKDTGFIVFAVLLLVSCLILIF---VIAPRYGQRNILIYIII-------CSVI 296

Query: 153 GAFVSITMQNIGAMSSYLF----IIKYELPEVIRAFMGLEENTGEWYLNGNYLIIFVSVG 208
           GAF    ++ +G      F    ++++ LP ++   + L  +T   +LN   L IF +  
Sbjct: 297 GAFSVAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLN-RALDIF-NTS 354

Query: 209 IILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPVLDHSVGNLSFNNTLP 268
           ++ P+       Y+ +T+      +V   S++++K++     + +     G LS   T+ 
Sbjct: 355 LVFPIY------YVFFTT------VVVTSSIILFKEWYSMSAVDI----AGTLSGFVTII 398

Query: 269 MHVVMLPNNSESSDVNFMMDYTHRNP-------AGLDENQAKGSLHDSGVEYEAHSDDKC 321
           + V ML    +       + + H+NP         +   + K  L D+ +E  + S  + 
Sbjct: 399 LGVFMLHAFKDLDISCASLPHMHKNPPPSPAPEPTVIRLEDKNVLVDN-IELASTSSPEE 457

Query: 322 EPKYFVFNS 330
           +PK F+ +S
Sbjct: 458 KPKVFIIHS 466


>gi|162287219 prune homolog 2 [Homo sapiens]
          Length = 3088

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 18/59 (30%), Positives = 26/59 (44%)

Query: 14   DDESSSGESAPDSYIGIGNSEKAAMSSQFANEDTESQKFLTNGFLGKKKLADYADEHHP 72
            DD+S  GE + +  I + N   A   S+  +   ES KFL       + + DY D   P
Sbjct: 1688 DDDSVGGEESIEEEIQVANCHVAEDESRAWDSLNESNKFLVTADPKSENIYDYLDSSEP 1746


>gi|4885329 free fatty acid receptor 3 [Homo sapiens]
          Length = 346

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 40/180 (22%), Positives = 75/180 (41%), Gaps = 14/180 (7%)

Query: 321 CEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYL 380
           C    F+F   T   +  L  A V     L +   L  ++R ++     +S+      +L
Sbjct: 88  CPLSGFIFF--TTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVA----CWL 141

Query: 381 LAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSVIT 440
           LA+    + +  E   ++ H+     T  +     +LA+L+ V L + +VLF +   + +
Sbjct: 142 LASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLIITS 201

Query: 441 LLFPK------RPFSWIRHFLIAAVLIA-LNNVLVILVP-TIKYIFGFIGASSATMLIFI 492
             + +      R  S  R   +A +L A L N LV   P  + ++ G+I   S    I++
Sbjct: 202 YCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYICGESPAWRIYV 261


>gi|9257240 neuroplastin isoform a precursor [Homo sapiens]
          Length = 282

 Score = 30.4 bits (67), Expect = 4.4
 Identities = 24/107 (22%), Positives = 44/107 (41%), Gaps = 2/107 (1%)

Query: 160 MQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNL 219
           M  +     +  I K    E+    + + E+ GE+  N    I   S  ++  L +  +L
Sbjct: 164 MDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI--GSASVVTVLRVRSHL 221

Query: 220 GYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPVLDHSVGNLSFNNT 266
             L    G     ++  V +V+Y+K + P  +P  D   G +  N+T
Sbjct: 222 APLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDDDEPAGPMKTNST 268


>gi|6912646 neuroplastin isoform b precursor [Homo sapiens]
          Length = 398

 Score = 30.4 bits (67), Expect = 4.4
 Identities = 24/107 (22%), Positives = 44/107 (41%), Gaps = 2/107 (1%)

Query: 160 MQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNL 219
           M  +     +  I K    E+    + + E+ GE+  N    I   S  ++  L +  +L
Sbjct: 280 MDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI--GSASVVTVLRVRSHL 337

Query: 220 GYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPVLDHSVGNLSFNNT 266
             L    G     ++  V +V+Y+K + P  +P  D   G +  N+T
Sbjct: 338 APLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDDDEPAGPMKTNST 384


>gi|40788011 claudin 8 [Homo sapiens]
          Length = 225

 Score = 30.4 bits (67), Expect = 4.4
 Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 3/73 (4%)

Query: 467 LVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFM 526
           L+ L P ++   G + A+S    +  + A+  +K  +       +KV A I L  GI F+
Sbjct: 70  LLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTR--CTGDNEKVKAHILLTAGIIFI 127

Query: 527 I-GSMALIIIDWI 538
           I G + LI + W+
Sbjct: 128 ITGMVVLIPVSWV 140


>gi|4557457 nicotinic cholinergic receptor alpha 1 isoform b
           precursor [Homo sapiens]
          Length = 457

 Score = 30.0 bits (66), Expect = 5.7
 Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 6/101 (5%)

Query: 413 LMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVI--- 469
           +M RL +   V + +P +LF   T    L+F     S  +  L  +VL++L   L++   
Sbjct: 226 VMQRLPLYFIVNVIIPCLLFSFLTG---LVFYLPTDSGEKMTLSISVLLSLTVFLLVIVE 282

Query: 470 LVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKETFRSP 510
           L+P+       IG      ++F++ ++    +V     RSP
Sbjct: 283 LIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHHRSP 323


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.140    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,614,584
Number of Sequences: 37866
Number of extensions: 756173
Number of successful extensions: 1837
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1769
Number of HSP's gapped (non-prelim): 58
length of query: 547
length of database: 18,247,518
effective HSP length: 107
effective length of query: 440
effective length of database: 14,195,856
effective search space: 6246176640
effective search space used: 6246176640
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.