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Search of human proteins with 169790853
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
(505 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169790853 keratin, hair, basic, 1 [Homo sapiens] 1020 0.0
gi|169790841 keratin 83 [Homo sapiens] 939 0.0
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap... 897 0.0
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap... 897 0.0
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap... 897 0.0
gi|14318422 keratin 86 [Homo sapiens] 897 0.0
gi|4504935 keratin 85 [Homo sapiens] 778 0.0
gi|15431316 keratin, hair, basic, 4 [Homo sapiens] 546 e-155
gi|27477127 keratin 82 [Homo sapiens] 531 e-151
gi|119395754 keratin 5 [Homo sapiens] 437 e-122
gi|5031839 keratin 6A [Homo sapiens] 433 e-121
gi|155969697 keratin 6C [Homo sapiens] 430 e-120
gi|153791158 keratin 75 [Homo sapiens] 430 e-120
gi|119703753 keratin 6B [Homo sapiens] 429 e-120
gi|4504919 keratin 8 [Homo sapiens] 410 e-114
gi|109148552 keratin 3 [Homo sapiens] 410 e-114
gi|67782365 keratin 7 [Homo sapiens] 407 e-113
gi|15618995 keratin 71 [Homo sapiens] 402 e-112
gi|153791670 keratin 76 [Homo sapiens] 402 e-112
gi|109255249 keratin 4 [Homo sapiens] 402 e-112
gi|119395750 keratin 1 [Homo sapiens] 401 e-112
gi|28173564 keratin 73 [Homo sapiens] 400 e-111
gi|28372503 keratin 72 isoform 1 [Homo sapiens] 392 e-109
gi|226246663 keratin 72 isoform 1 [Homo sapiens] 392 e-109
gi|47132620 keratin 2 [Homo sapiens] 388 e-108
gi|32567786 keratin 6L [Homo sapiens] 388 e-108
gi|148612803 keratin 6 irs4 [Homo sapiens] 379 e-105
gi|194018511 keratin 77 [Homo sapiens] 354 9e-98
gi|89357932 keratin 5b [Homo sapiens] 349 3e-96
gi|226246665 keratin 72 isoform 2 [Homo sapiens] 336 3e-92
>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
Length = 505
Score = 1020 bits (2638), Expect = 0.0
Identities = 505/505 (100%), Positives = 505/505 (100%)
Query: 1 MTCGSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
MTCGSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG
Sbjct: 1 MTCGSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
Query: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF
Sbjct: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
Query: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
Query: 241 RLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
RLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK
Sbjct: 241 RLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
Query: 421 IGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLNTTCGG 480
IGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLNTTCGG
Sbjct: 421 IGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLNTTCGG 480
Query: 481 GSCGVGSCGISSLGVGSCGSSCRKC 505
GSCGVGSCGISSLGVGSCGSSCRKC
Sbjct: 481 GSCGVGSCGISSLGVGSCGSSCRKC 505
>gi|169790841 keratin 83 [Homo sapiens]
Length = 493
Score = 939 bits (2428), Expect = 0.0
Identities = 468/491 (95%), Positives = 473/491 (96%), Gaps = 5/491 (1%)
Query: 1 MTCG-----SGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55
MTCG GF FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR
Sbjct: 1 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60
Query: 56 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115
AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS
Sbjct: 61 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120
Query: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175
RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR
Sbjct: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180
Query: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235
LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE
Sbjct: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240
Query: 236 IDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295
IDFLRRLYEEEI ILQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES
Sbjct: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300
Query: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355
WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ
Sbjct: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360
Query: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415
QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ
Sbjct: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420
Query: 416 RLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLN 475
RLCEG+ AVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGN+ VSTGLC PCGQLN
Sbjct: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCGQLN 480
Query: 476 TTCGGGSCGVG 486
TTCGGGSCG G
Sbjct: 481 TTCGGGSCGQG 491
>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 486
Score = 897 bits (2319), Expect = 0.0
Identities = 457/507 (90%), Positives = 465/507 (91%), Gaps = 23/507 (4%)
Query: 1 MTCGSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
MTCGS GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG
Sbjct: 1 MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
Query: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF
Sbjct: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
Query: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
Query: 241 RLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
RLYEEEI +LQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK
Sbjct: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
Query: 421 IGAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNVAV-STGLCAPCGQLNTTC 478
+G+VNVCVSSSRGGVVCGDLC S + PV + V S P N NV V +T CAP
Sbjct: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAP-------- 472
Query: 479 GGGSCGVGSCGISSLGVGSCGSSCRKC 505
S VG CG SC++C
Sbjct: 473 -------------SARVGVCGGSCKRC 486
>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 486
Score = 897 bits (2319), Expect = 0.0
Identities = 457/507 (90%), Positives = 465/507 (91%), Gaps = 23/507 (4%)
Query: 1 MTCGSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
MTCGS GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG
Sbjct: 1 MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
Query: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF
Sbjct: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
Query: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
Query: 241 RLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
RLYEEEI +LQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK
Sbjct: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
Query: 421 IGAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNVAV-STGLCAPCGQLNTTC 478
+G+VNVCVSSSRGGVVCGDLC S + PV + V S P N NV V +T CAP
Sbjct: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAP-------- 472
Query: 479 GGGSCGVGSCGISSLGVGSCGSSCRKC 505
S VG CG SC++C
Sbjct: 473 -------------SARVGVCGGSCKRC 486
>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
sapiens]
Length = 486
Score = 897 bits (2319), Expect = 0.0
Identities = 457/507 (90%), Positives = 465/507 (91%), Gaps = 23/507 (4%)
Query: 1 MTCGSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
MTCGS GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG
Sbjct: 1 MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
Query: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF
Sbjct: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
Query: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
Query: 241 RLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
RLYEEEI +LQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK
Sbjct: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
Query: 421 IGAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNVAV-STGLCAPCGQLNTTC 478
+G+VNVCVSSSRGGVVCGDLC S + PV + V S P N NV V +T CAP
Sbjct: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAP-------- 472
Query: 479 GGGSCGVGSCGISSLGVGSCGSSCRKC 505
S VG CG SC++C
Sbjct: 473 -------------SARVGVCGGSCKRC 486
>gi|14318422 keratin 86 [Homo sapiens]
Length = 486
Score = 897 bits (2319), Expect = 0.0
Identities = 457/507 (90%), Positives = 465/507 (91%), Gaps = 23/507 (4%)
Query: 1 MTCGSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
MTCGS GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG
Sbjct: 1 MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
Query: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF
Sbjct: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
Query: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
Query: 241 RLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
RLYEEEI +LQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK
Sbjct: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
Query: 421 IGAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNVAV-STGLCAPCGQLNTTC 478
+G+VNVCVSSSRGGVVCGDLC S + PV + V S P N NV V +T CAP
Sbjct: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAP-------- 472
Query: 479 GGGSCGVGSCGISSLGVGSCGSSCRKC 505
S VG CG SC++C
Sbjct: 473 -------------SARVGVCGGSCKRC 486
>gi|4504935 keratin 85 [Homo sapiens]
Length = 507
Score = 778 bits (2010), Expect = 0.0
Identities = 401/487 (82%), Positives = 430/487 (88%), Gaps = 16/487 (3%)
Query: 10 RAFSCISACGPRPG-RCCITAAPYRGISCYRGLTGGFGSHSVC-----------GGFRAG 57
R FS SA P+ G RCCI+AAPYRG+SCYRGLT GFGS S+C GGFRAG
Sbjct: 16 RNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLT-GFGSRSLCNLGSCGPRIAVGGFRAG 74
Query: 58 SCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRF 117
SCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRF
Sbjct: 75 SCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRF 134
Query: 118 AAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLA 177
AAFIDKVRFLEQQNKLLETK QFYQN+ CC+SNLEPLF GYIETLRREAECVEADSGRLA
Sbjct: 135 AAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETLRREAECVEADSGRLA 194
Query: 178 SELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEID 237
SELNHVQEVLEGYKKKYEEEV+LRATAENEFV LKKDVDCAYLRKSDLEANVEAL++E
Sbjct: 195 SELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESS 254
Query: 238 FLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWY 297
FLRRLYEEEI +LQ+HISDTSV+VK+DNSRDLNMDCIIAEIKAQYDD+ +RSRAEAESWY
Sbjct: 255 FLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWY 314
Query: 298 RSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQG 357
RSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE+ENAKCQ +KLEAAVA++EQQG
Sbjct: 315 RSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQG 374
Query: 358 EAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL 417
EAALSDARCKLAELEGALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRLLEGEE RL
Sbjct: 375 EAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRL 434
Query: 418 CEGIGAVNVCVSSSRGGVVCGDLCVSGS--RPVTGSVCSAPCNGNVAVSTGLCAPCGQLN 475
CEG+G+VNVCVSSSRGGV CG L S + R +T S SA V+ CAPC +
Sbjct: 435 CEGVGSVNVCVSSSRGGVSCGGLSYSTTPGRQIT-SGPSAIGGSITVVAPDSCAPCQPRS 493
Query: 476 TTCGGGS 482
++ GS
Sbjct: 494 SSFSCGS 500
>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
Length = 600
Score = 546 bits (1406), Expect = e-155
Identities = 300/497 (60%), Positives = 367/497 (73%), Gaps = 28/497 (5%)
Query: 3 CGSGFG-GRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGR 61
CG GFG GR GPR C GL GFG+ S G G G
Sbjct: 83 CGMGFGDGRGVGL----GPRADSCV-------------GL--GFGAGS---GIGYGFGGP 120
Query: 62 SFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFI 121
FGYR GGV P+ P IT V+VN+SLLTPLNLEIDPNAQ VK++EKEQIK+LN++FA+FI
Sbjct: 121 GFGYRVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFI 180
Query: 122 DKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELN 181
DKVRFLEQQNKLLETK F Q ++C +SNLEPLFE YI LRR+ E + +D RL +E N
Sbjct: 181 DKVRFLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERN 240
Query: 182 HVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRR 241
H+Q+VLEG+KKKYEEEV RA AENEFVALKKDVD A++ KSDLEANV+ L QEIDFL+
Sbjct: 241 HLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKT 300
Query: 242 LYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKC 301
LY EEI +LQSHIS+TSV+VK+DNSRDLN+D IIAE+KAQY+++ RSRA+AE+WY++K
Sbjct: 301 LYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKY 360
Query: 302 EEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAAL 361
EEM+ T +H + LR + EINEL R+IQRL AE+E+AK Q +KLEAAVA++EQQGEA L
Sbjct: 361 EEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATL 420
Query: 362 SDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGI 421
SDA+CKLA+LE ALQ+AKQDMA + EYQE+MN+KLGLDIEIATYRRLLEGEE RLCEG+
Sbjct: 421 SDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGV 480
Query: 422 GAVNVCVSSSRGGVVCG-DLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLNTTCGG 480
G VN+ VSSSRGG+VCG + V+GS G V + + +V ++G+ A CG + GG
Sbjct: 481 GPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSG-SSSVCATSGVLASCG---PSLGG 536
Query: 481 GSCGVGSCGISSLGVGS 497
+ + S G S
Sbjct: 537 ARVAPATGDLLSTGTRS 553
>gi|27477127 keratin 82 [Homo sapiens]
Length = 513
Score = 531 bits (1368), Expect = e-151
Identities = 302/514 (58%), Positives = 359/514 (69%), Gaps = 28/514 (5%)
Query: 4 GSGFGGRAFSCISACGPRP-GRCCITAAPYRGISCYRGLT--GGFGSHSVCG-GFR---- 55
GS G ++FS SA PR ++ P R RGL G GS S+C GF
Sbjct: 9 GSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRP-GGGRGLRALGCLGSRSLCNVGFGRPRV 67
Query: 56 AGSCGRS---FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKS 112
A CG + FGYR G CGPS CIT V++NESLL PL LEIDP Q VK++EKEQIK
Sbjct: 68 ASRCGGTLPGFGYRLGATCGPSA-CITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKC 126
Query: 113 LNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEAD 172
LN+RFA+FI+KVRFLEQ+NKLLETK F Q + CCQ+N+EP+FEGYI LRR+ +CV D
Sbjct: 127 LNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCVSGD 186
Query: 173 SGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEAL 232
RL SEL +Q LEGYKKKYEEE+SLR ENEFVALKKDVD A+L K+DLE N EAL
Sbjct: 187 RVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEAL 246
Query: 233 IQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAE 292
+QEIDFL+ LYEEEI +LQS IS+TSV+VK+DNSR+L++D IIAEIKAQYDDI +RS+AE
Sbjct: 247 VQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAE 306
Query: 293 AESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQ 352
AE+WY+ + EE++ T H + LR K EI E+N++IQRL E EN K Q KLE A+A+
Sbjct: 307 AEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAE 366
Query: 353 SEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEG 412
+EQQGEAAL+DA+CKLA LE ALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRLLEG
Sbjct: 367 AEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEG 426
Query: 413 EEQRLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSV-----CSAPCNGNVAVSTGL 467
EE RLCEGIG VN+ VSSS+G + VS TG + CS G + V
Sbjct: 427 EEHRLCEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGELYVP--- 483
Query: 468 CAPCGQLNTTCGGGSCGVGSCGISSLGVGSCGSS 501
C P G L SCG G +LG G S
Sbjct: 484 CEPQGLL-------SCGSGRKSSMTLGAGGSSPS 510
>gi|119395754 keratin 5 [Homo sapiens]
Length = 590
Score = 437 bits (1124), Expect = e-122
Identities = 255/492 (51%), Positives = 335/492 (68%), Gaps = 28/492 (5%)
Query: 40 GLTGGFGSHSVCGGFRAGSCGRSFGYR-SGGVCGPS-PPC----ITTVSVNESLLTPLNL 93
G GG GS GG G G G GG GP P C I V+VN+SLLTPLNL
Sbjct: 96 GFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 155
Query: 94 EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 151
+IDP+ Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK Q + + + NL
Sbjct: 156 QIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 215
Query: 152 EPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVAL 211
EPLFE YI LRR+ + + + GRL SEL ++Q+++E +K KYE+E++ R TAENEFV L
Sbjct: 216 EPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVML 275
Query: 212 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNM 271
KKDVD AY+ K +LEA V+AL+ EI+F++ ++ E+ +Q+H+SDTSVV+ +DN+R+L++
Sbjct: 276 KKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDL 335
Query: 272 DCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 331
D IIAE+KAQY++I RSR EAESWY++K EE++ T RHG+ LR TK EI+E+NRMIQR
Sbjct: 336 DSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQR 395
Query: 332 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 391
L AE++N K Q + L+ A+A +EQ+GE AL DAR KLAELE ALQKAKQDMA L+REYQE
Sbjct: 396 LRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQE 455
Query: 392 VMNSKLGLDIEIATYRRLLEGEEQRLC-EGIGAVNVCVSSSR---------------GGV 435
+MN+KL LD+EIATYR+LLEGEE RL EG+G VN+ V +S GG
Sbjct: 456 LMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGG 515
Query: 436 VCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLNTTCGGG-SCGVGSCGISSLG 494
+ G L + +GS S+ +G V + GL + + G G G GS G SS
Sbjct: 516 LGGGLGGGLAGGSSGSYYSS-SSGGVGLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSS 574
Query: 495 VG--SCGSSCRK 504
V S SS RK
Sbjct: 575 VKFVSTTSSSRK 586
>gi|5031839 keratin 6A [Homo sapiens]
Length = 564
Score = 433 bits (1113), Expect = e-121
Identities = 258/520 (49%), Positives = 337/520 (64%), Gaps = 31/520 (5%)
Query: 4 GSGFGGRAF------SCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAG 57
G+GFG R+ IS G G C I+ G G + GFG GF G
Sbjct: 53 GAGFGSRSLYGLGGSKRISIGG---GSCAISG----GYGSRAGGSYGFGGAGSGFGF-GG 104
Query: 58 SCGRSFGYR-----SGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEK 107
G FG +GG GP P C I V+VN+SLLTPLNL+IDP Q V+ EE+
Sbjct: 105 GAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEER 164
Query: 108 EQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNLEPLFEGYIETLRRE 165
EQIK+LN++FA+FIDKVRFLEQQNK+LETK Q + + + NLEPLFE YI LRR+
Sbjct: 165 EQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQ 224
Query: 166 AECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDL 225
+ + + GRL SEL +Q+++E +K KYE+E++ R AENEFV LKKDVD AY+ K +L
Sbjct: 225 LDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVEL 284
Query: 226 EANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDI 285
+A + L EI+FLR LY+ E+ +Q+HISDTSVV+ +DN+R+L++D IIAE+KAQY++I
Sbjct: 285 QAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEI 344
Query: 286 VTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSK 345
RSRAEAESWY++K EE++ T RHG+ LR TK+EI E+NRMIQRL +E+++ K Q +
Sbjct: 345 AQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCAN 404
Query: 346 LEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIAT 405
L+AA+A +EQ+GE AL DA+ KL LE ALQKAKQD+A L++EYQE+MN KL LD+EIAT
Sbjct: 405 LQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIAT 464
Query: 406 YRRLLEGEEQRL-CEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVS 464
YR+LLEGEE RL EG+G VN+ V S G GS G S + V
Sbjct: 465 YRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVG 524
Query: 465 TGLCAPCGQLNTTCGGGSCGVGSCGISSLGVGSCGSSCRK 504
G + G+ GGG VG G S++ + SS RK
Sbjct: 525 GGFSSSSGR---AIGGGLSSVGG-GSSTIKYTTTSSSSRK 560
>gi|155969697 keratin 6C [Homo sapiens]
Length = 564
Score = 430 bits (1106), Expect = e-120
Identities = 257/520 (49%), Positives = 337/520 (64%), Gaps = 31/520 (5%)
Query: 4 GSGFGGRAF------SCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAG 57
G+GFG R+ IS G G C I+ G G + GFG GF G
Sbjct: 53 GAGFGSRSLYGLGGSKRISIGG---GSCAISG----GYGSRAGGSYGFGGAGSGFGF-GG 104
Query: 58 SCGRSFGYR-----SGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEK 107
G FG +GG GP P C I V+VN+SLLTPLNL+IDP Q V+ EE+
Sbjct: 105 GAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEER 164
Query: 108 EQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNLEPLFEGYIETLRRE 165
EQIK+LN++FA+FIDKVRFLEQQNK+L+TK Q + + + NLEPLFE YI LRR+
Sbjct: 165 EQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQ 224
Query: 166 AECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDL 225
+ + + GRL SEL ++Q+++E K KYE+E++ R AENEFV LKKDVD AY+ K +L
Sbjct: 225 LDSIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVEL 284
Query: 226 EANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDI 285
+A + L EI+FLR LY+ E+ +Q+HISDTSVV+ +DN+R+L++D IIAE+KAQY++I
Sbjct: 285 QAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEI 344
Query: 286 VTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSK 345
RSRAEAESWY++K EE++ T RHG+ LR TK+EI E+NRMIQRL +E+++ K Q +
Sbjct: 345 AQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCAS 404
Query: 346 LEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIAT 405
L+AA+A +EQ+GE AL DA+ KL LE ALQKAKQD+A L++EYQE+MN KL LD+EIAT
Sbjct: 405 LQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIAT 464
Query: 406 YRRLLEGEEQRL-CEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVS 464
YR+LLEGEE RL EG+G VNV V S G GS G S + +
Sbjct: 465 YRKLLEGEECRLNGEGVGQVNVSVVQSTISSGYGGASGVGSGLGLGGGSSYSYGSGLGIG 524
Query: 465 TGLCAPCGQLNTTCGGGSCGVGSCGISSLGVGSCGSSCRK 504
G + G+ GGG VG G S++ + SS RK
Sbjct: 525 GGFSSSSGR---AIGGGLSSVGG-GSSTIKYTTTSSSSRK 560
>gi|153791158 keratin 75 [Homo sapiens]
Length = 551
Score = 430 bits (1106), Expect = e-120
Identities = 262/540 (48%), Positives = 343/540 (63%), Gaps = 63/540 (11%)
Query: 10 RAFSCISACGPRPGRCCIT-------AAPYRGISCYRGLTGGFGSHSV------------ 50
R FS SA P GR + AA G+ FGS S+
Sbjct: 15 RGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLYNLGGAKRVSIN 74
Query: 51 -CGGF-RAGSCGRS---------FGYRSG---GVCGPS-PPC----ITTVSVNESLLTPL 91
CG R+G GR+ FGY G G GPS P C I V+VN+SLLTPL
Sbjct: 75 GCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEVTVNQSLLTPL 134
Query: 92 NLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQS 149
+L+IDP Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK Q + +
Sbjct: 135 HLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQ 194
Query: 150 NLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFV 209
NLEPLF+ Y LRR+ E + + GRL +EL ++Q+V+E +K +YE+E++ R AENEFV
Sbjct: 195 NLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFV 254
Query: 210 ALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDL 269
ALKKDVD AY+ K +LEA V++L +EI+F+ +++ E+ LQ+ + DTSVV+ +DN+R+L
Sbjct: 255 ALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNL 314
Query: 270 NMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMI 329
++D IIAE+KAQY+DI RSRAEAESWY++K EE++ T RHG+ LR TK+EI+E+NRMI
Sbjct: 315 DLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMI 374
Query: 330 QRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREY 389
QRL AE+++ K Q S L+ A+A +EQ+GE AL DAR KL +LE ALQKAKQDMA L+REY
Sbjct: 375 QRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREY 434
Query: 390 QEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGIGAVNVCVSSSRGGVVCGDLCVSGSRPV 448
QE+MN KL LD+EIATYR+LLEGEE RL EG+ VN+ V +S G SGS
Sbjct: 435 QELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYG----SGSSIG 490
Query: 449 TGSVCSAPCNGNVAVSTGLCAPCGQLNTTCGGGSCGVGSCG-----ISSLGVGSCGSSCR 503
G++ GL G TT GG S G G G S+ G+G GSS +
Sbjct: 491 GGNL-------------GLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSSVK 537
>gi|119703753 keratin 6B [Homo sapiens]
Length = 564
Score = 429 bits (1104), Expect = e-120
Identities = 257/520 (49%), Positives = 337/520 (64%), Gaps = 31/520 (5%)
Query: 4 GSGFGGRAF------SCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAG 57
G+GFG R+ IS G G C I+ G G + GFG GF G
Sbjct: 53 GAGFGSRSLYGLGGSKRISIGG---GSCAISG----GYGSRAGGSYGFGGAGSGFGF-GG 104
Query: 58 SCGRSFGYR-----SGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEK 107
G FG +GG GP P C I V+VN+SLLTPLNL+IDP Q V+ EE+
Sbjct: 105 GAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEER 164
Query: 108 EQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNLEPLFEGYIETLRRE 165
EQIK+LN++FA+FIDKVRFLEQQNK+L+TK Q + + + NLEPLFE YI LRR+
Sbjct: 165 EQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQ 224
Query: 166 AECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDL 225
+ + + GRL SEL ++Q+++E K KYE+E++ R AENEFV LKKDVD AY+ K +L
Sbjct: 225 LDNIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVEL 284
Query: 226 EANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDI 285
+A + L EI+FLR LY+ E+ +Q+HISDTSVV+ +DN+R+L++D IIAE+KAQY++I
Sbjct: 285 QAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEI 344
Query: 286 VTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSK 345
RSRAEAESWY++K EE++ T RHG+ LR TK+EI E+NRMIQRL +E+++ K Q +
Sbjct: 345 AQRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCAN 404
Query: 346 LEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIAT 405
L+AA+A +EQ+GE AL DA+ KL LE ALQKAKQD+A L++EYQE+MN KL LD+EIAT
Sbjct: 405 LQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIAT 464
Query: 406 YRRLLEGEEQRL-CEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVS 464
YR+LLEGEE RL EG+G VN+ V S G GS G S + V
Sbjct: 465 YRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVG 524
Query: 465 TGLCAPCGQLNTTCGGGSCGVGSCGISSLGVGSCGSSCRK 504
G + G+ GGG VG G S++ + SS RK
Sbjct: 525 GGFSSSSGR---ATGGGLSSVGG-GSSTIKYTTTSSSSRK 560
>gi|4504919 keratin 8 [Homo sapiens]
Length = 483
Score = 410 bits (1055), Expect = e-114
Identities = 225/427 (52%), Positives = 296/427 (69%), Gaps = 25/427 (5%)
Query: 8 GGRAFSCISACGPRPGRCCITAAPYRGISCYRG-LTGGFGSHSVCGGFRAGSCGRSFGYR 66
G RAFS S R ++ G S +RG L GG+G S GG
Sbjct: 16 GPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGG------------- 62
Query: 67 SGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRF 126
IT V+VN+SLL+PL LE+DPN Q V+ +EKEQIK+LN++FA+FIDKVRF
Sbjct: 63 -----------ITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRF 111
Query: 127 LEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEV 186
LEQQNK+LETK Q ++ +SN++ +FE YI LRR+ E + + +L +EL ++Q +
Sbjct: 112 LEQQNKMLETKWSLLQQQKTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGL 171
Query: 187 LEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEE 246
+E +K KYE+E++ R ENEFV +KKDVD AY+ K +LE+ +E L EI+FLR+LYEEE
Sbjct: 172 VEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEE 231
Query: 247 ILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKA 306
I LQS ISDTSVV+ +DNSR L+MD IIAE+KAQY+DI RSRAEAES Y+ K EE+++
Sbjct: 232 IRELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQS 291
Query: 307 TVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARC 366
+HG+ LRRTK EI+E+NR I RL AE+E K Q + LEAA+A +EQ+GE A+ DA
Sbjct: 292 LAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANA 351
Query: 367 KLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGIGAVNV 426
KL+ELE ALQ+AKQDMA +REYQE+MN KL LDIEIATYR+LLEGEE RL G+ +++
Sbjct: 352 KLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSI 411
Query: 427 CVSSSRG 433
++ G
Sbjct: 412 HTKTTSG 418
>gi|109148552 keratin 3 [Homo sapiens]
Length = 628
Score = 410 bits (1054), Expect = e-114
Identities = 250/521 (47%), Positives = 324/521 (62%), Gaps = 37/521 (7%)
Query: 6 GFGGRAFSCISACGPRPGRCCITAAPYRG-ISCYRGLTGGFGSHSVCGGFRAGSCGRSFG 64
GFGG SC A G G + G RG+ GGFG GG AG G + G
Sbjct: 79 GFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGG--AGGFGGAGG 136
Query: 65 YR-------SGGVCGPS-------------PPCITTVSVNESLLTPLNLEIDPNAQCVKQ 104
+ SGG GP P I V++N+SLL PLN+EIDP VK
Sbjct: 137 FGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQPLNVEIDPQIGQVKA 196
Query: 105 EEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ----SNLEPLFEGYIE 160
+E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK Q + +NLEPLFE +I
Sbjct: 197 QEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLFENHIN 256
Query: 161 TLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYL 220
LR + + + GRL SEL ++++++E +KKKYE+E++ R AENEFV LKKDVD AY+
Sbjct: 257 YLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDSAYM 316
Query: 221 RKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKA 280
K +L+A V+ALI EIDFLR LY+ E+ +QSHISDTSVV+ +DN+R L++D IIAE++A
Sbjct: 317 NKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSIIAEVRA 376
Query: 281 QYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAK 340
QY+DI RS+AEAE+ Y++K E++ T RHG+ LR TK EI ELNRMIQRL AE+E K
Sbjct: 377 QYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAEIEGVK 436
Query: 341 CQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLD 400
QN+ L+ A+A++EQ GE AL DA KL EL+ ALQ+AK D+A L+R+YQE+MN KL LD
Sbjct: 437 KQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNVKLALD 496
Query: 401 IEIATYRRLLEGEEQRL---CEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPC 457
+EIATYR+LLEGEE R+ C +++V VSSS G G G
Sbjct: 497 VEIATYRKLLEGEEYRMSGECPSAVSISV-VSSSTTSASAG-----GYGGGYGGGMGGGL 550
Query: 458 NGNVAVSTGLCAPCGQLNTTCGGGSCGVGSCGIS-SLGVGS 497
G + G + G+ GG G GS G S G GS
Sbjct: 551 GGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGS 591
>gi|67782365 keratin 7 [Homo sapiens]
Length = 469
Score = 407 bits (1045), Expect = e-113
Identities = 221/398 (55%), Positives = 289/398 (72%), Gaps = 6/398 (1%)
Query: 43 GGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 102
GG GS S+ G G+ RS GP I V++N+SLL PL L+ DP+ Q V
Sbjct: 32 GGLGSSSLYG---LGASRPRVAVRSA-YGGPVGAGIREVTINQSLLAPLRLDADPSLQRV 87
Query: 103 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEP-LFEGYIET 161
+QEE EQIK+LN++FA+FIDKVRFLEQQNKLLETK Q ++ +S+ P +FE I
Sbjct: 88 RQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRLPDIFEAQIAG 147
Query: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221
LR + E ++ D GRL +EL +Q+V+E +K KYE+E++ R AENEFV LKKDVD AY+
Sbjct: 148 LRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMS 207
Query: 222 KSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281
K +LEA V+AL EI+FLR L E E+ LQS ISDTSVV+ +DNSR L++D IIAE+KAQ
Sbjct: 208 KVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQ 267
Query: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341
Y+++ SRAEAE+WY++K E ++A +HG+ LR T+ EI+E+NR IQRL AE++N K
Sbjct: 268 YEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKN 327
Query: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401
Q +KLEAA+A++E++GE AL DAR K ELE ALQ+ KQDMA +REYQE+M+ KL LDI
Sbjct: 328 QRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDI 387
Query: 402 EIATYRRLLEGEEQRLC-EGIGAVNVCVSSSRGGVVCG 438
EIATYR+LLEGEE RL +G+GAVN+ V +S GG G
Sbjct: 388 EIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSG 425
>gi|15618995 keratin 71 [Homo sapiens]
Length = 523
Score = 402 bits (1034), Expect = e-112
Identities = 233/481 (48%), Positives = 319/481 (66%), Gaps = 37/481 (7%)
Query: 10 RAFSCISACGPRPGRCCITAAPYRGISCY-----RGLTGGFGSHSV--CGGFR----AGS 58
R F+C S + G +A G S +GL+GGFGS S+ GG R A
Sbjct: 3 RQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASG 62
Query: 59 CGRSFGY-----RSGGVCGP-------SPPCITT--------VSVNESLLTPLNLEIDPN 98
G+S GY R+ G G P C T V+VNESLL PLN+E+DP
Sbjct: 63 SGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPE 122
Query: 99 AQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFE 156
Q V+ +E+EQIK+LN++FA+FIDKVRFLEQQN++LETK + Q + C++NLEP+ E
Sbjct: 123 IQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILE 182
Query: 157 GYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVD 216
GYI LR++ E + D RL SEL +V++V+E YKK+YEEE++ R AENEFV LKKDVD
Sbjct: 183 GYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVD 242
Query: 217 CAYLRKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIA 276
AY K +L+A VE++ QEI F R L+E EI +QSHISD SV++ +DN+R+L++D II
Sbjct: 243 AAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIID 302
Query: 277 EIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEV 336
E++ QY++I +S+AEAE+ Y++K +E++ RHG+ L+ TK EI+EL R+IQR+ +E+
Sbjct: 303 EVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEI 362
Query: 337 ENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSK 396
EN K Q S LE A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+M+ K
Sbjct: 363 ENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLK 422
Query: 397 LGLDIEIATYRRLLEGEEQRLC-EGIGAVNV-CVSSSRGGVVCG--DLCVSGSRPVTGSV 452
L LD+EIATYR+LLE EE R+ E V++ +SS+ GG V G VSG S
Sbjct: 423 LALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGSVYGFRPSMVSGGYVANSSN 482
Query: 453 C 453
C
Sbjct: 483 C 483
>gi|153791670 keratin 76 [Homo sapiens]
Length = 638
Score = 402 bits (1034), Expect = e-112
Identities = 246/515 (47%), Positives = 324/515 (62%), Gaps = 24/515 (4%)
Query: 6 GFGGRAFSCISACGPRPGRCCITAAPY---RGISCYRGLTGGFGSHSVCGGFRAGSCGRS 62
GFGG SC A G G + RG+ G GGFG GG S
Sbjct: 80 GFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAGGFGGAGGFGGPGVFGGPGS 139
Query: 63 FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFID 122
FG G G P I V VN+SLL PLN+EIDP VK +E+EQIK+LN++FA+FID
Sbjct: 140 FGGPGGFGPGGFPGGIQEVIVNQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFID 199
Query: 123 KVRFLEQQNKLLETKLQFYQNRECCQ--SNLEPLFEGYIETLRREAECVEADSGRLASEL 180
KVRFLEQQNK+LETK + Q + S+LEP FE YI L ++ + + + G L EL
Sbjct: 200 KVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFESYISFLCKQLDSLLGERGNLEGEL 259
Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
+Q+++E +KKKYE+E++ R AENEFV LKKDVD A++ K +L+A V++L E+ FLR
Sbjct: 260 KSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDAAFMNKVELQAKVDSLTDEVSFLR 319
Query: 241 RLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
LYE E+ +QSH SDTSVV+ +DN+R L++ IIAE++AQY++I RS++EAE+ Y++K
Sbjct: 320 TLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAEVRAQYEEIAQRSKSEAEALYQTK 379
Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
E++ T RHG+ LR TK EI ELNRMIQRL AE+EN K QN+ L+ A+A++EQ+GE A
Sbjct: 380 LGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIENVKKQNANLQTAIAEAEQRGEMA 439
Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
L DA KL +L+ ALQKAK D+A L+R+YQE+MN KL LD+EIATYR+LLEGEE R+ G
Sbjct: 440 LKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRM-SG 498
Query: 421 IGAVNVCVS-------------SSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGL 467
VC+S SSRG V G + SGS G S+ +G VS G
Sbjct: 499 ECQSAVCISVVSNVTSTSGSSGSSRG--VFGGVSGSGSGGYKGGSSSSSSSG-YGVSGGS 555
Query: 468 CAPCGQLNTTCGGGSCGVGSCGISSLG--VGSCGS 500
+ G +++ GG GS SS G +G GS
Sbjct: 556 GSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGGAGS 590
>gi|109255249 keratin 4 [Homo sapiens]
Length = 594
Score = 402 bits (1034), Expect = e-112
Identities = 228/462 (49%), Positives = 312/462 (67%), Gaps = 24/462 (5%)
Query: 2 TCGSGF--GGR--AFSCISACGPRPGRCCITAAPYRGISCYRG-----LTGGFGSHSVC- 51
+CGS GG+ AFS +S G GRC R + RG ++ C
Sbjct: 90 SCGSAIVGGGKRGAFSSVSMSGGA-GRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGACF 148
Query: 52 ---GGFRAGSCGRSFGYRSGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVK 103
GGF G G FG G GP P C I V++N+SLLTPL++EIDP Q V+
Sbjct: 149 GGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDPEIQKVR 208
Query: 104 QEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFEGYIET 161
EE+EQIK LN++FA+FIDKV+FLEQQNK+LETK Q + S NLEPLFE Y+
Sbjct: 209 TEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFETYLSV 268
Query: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221
LR++ + + D GRL SEL +Q+ +E +K KYEEE++ R AEN+FV LKKDVD AYL
Sbjct: 269 LRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYLN 328
Query: 222 KSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281
K +LEA V++L EI+FL+ LY+ E+ +Q+H+SDTSVV+ +DN+R+L++D IIAE++AQ
Sbjct: 329 KVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRAQ 388
Query: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341
Y++I RS+AEAE+ Y++K ++++ +V +HG+ L+ TK EI ELNRMIQRL AE+EN K
Sbjct: 389 YEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIKK 448
Query: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401
Q L+ +VA +EQ+GE AL DA K ELE ALQ+AK+++A ++REYQE+M+ KL LDI
Sbjct: 449 QCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVKLALDI 508
Query: 402 EIATYRRLLEGEEQRL---CEGIGAVNVCVSSSRGGVVCGDL 440
EIATYR+LLEGEE R+ C+ +++V S+ G + G L
Sbjct: 509 EIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGL 550
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 401 bits (1030), Expect = e-112
Identities = 237/502 (47%), Positives = 322/502 (64%), Gaps = 36/502 (7%)
Query: 4 GSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRS- 62
G GFGG F + G G GGFGS GGF G G
Sbjct: 96 GGGFGGGGFG---------------GGGFGGGGIGGGGFGGFGSGG--GGFGGGGFGGGG 138
Query: 63 FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFID 122
+G G VC P I V++N+SLL PLN+EIDP Q VK E+EQIKSLN++FA+FID
Sbjct: 139 YGGGYGPVCPPGG--IQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFID 196
Query: 123 KVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFEGYIETLRREAECVEADSGRLASEL 180
KVRFLEQQN++L+TK + Q + NLEP FE +I LRR + +++D RL SEL
Sbjct: 197 KVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSEL 256
Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
++Q+++E Y+ KYE+E++ R AENEFV +KKDVD AY+ K DL+A ++ L QEIDFL
Sbjct: 257 KNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLT 316
Query: 241 RLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
LY+ E+ +Q+ IS+T+V++ +DN+R L++D IIAE+KAQY+DI +S+AEAES Y+SK
Sbjct: 317 ALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSK 376
Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
EE++ T RHG+++R +K EI+ELNR+IQRL +E++N K Q S L+ +++ +EQ+GE A
Sbjct: 377 YEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENA 436
Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
L DA+ KL +LE ALQ+AK+D+A L+R+YQE+MN+KL LD+EIATYR LLEGEE R+ G
Sbjct: 437 LKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRM-SG 495
Query: 421 IGAVNVCVS-SSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLNTTCG 479
A NV VS S+ + G G GS S+ +G + +G G
Sbjct: 496 ECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSG------------G 543
Query: 480 GGSCGVGSCGISSLGVGSCGSS 501
GG G GS G GS G S
Sbjct: 544 GGGGGRGSYGSGGSSYGSGGGS 565
>gi|28173564 keratin 73 [Homo sapiens]
Length = 540
Score = 400 bits (1029), Expect = e-111
Identities = 223/459 (48%), Positives = 309/459 (67%), Gaps = 21/459 (4%)
Query: 40 GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEID 96
G GG+G G +G G FG + G PS P I V++N+SLL PLN+E+D
Sbjct: 66 GWAGGYGFGR---GRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELD 122
Query: 97 PNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPL 154
P Q V+ +E+EQIK LN++FA+FIDKVRFLEQQN++LETK + Q + C++NLEP+
Sbjct: 123 PEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPI 182
Query: 155 FEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKD 214
EGYI LR++ E + D RL SEL V+EV+E YKK+YEEE++ R TAENEFV LKKD
Sbjct: 183 LEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKD 242
Query: 215 VDCAYLRKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCI 274
VD AY K +L+A V+AL EI F + LYE E +QSHISDTS+++ +DN+R+L++D I
Sbjct: 243 VDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSI 302
Query: 275 IAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTA 334
IAE++AQY++I +S+AEAE+ Y++K +E++ RHG+ L+ TK EI+EL R+IQRL +
Sbjct: 303 IAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRS 362
Query: 335 EVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMN 394
E+E+ K Q + LE A+A +EQ+G+ AL DAR KL ELEGALQ+AK+++A ++REYQE+++
Sbjct: 363 EIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLS 422
Query: 395 SKLGLDIEIATYRRLLEGEEQRLC-EGIGAVNVCVSSSRGGVVCGDLCVSG--------- 444
KL LDIEIATYR+LLEGEE R+ E +V++ V +S + G G
Sbjct: 423 VKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTYGY 482
Query: 445 -SRPVTGSVCSAPCNGNVAVSTGLCAPCGQLNTTCGGGS 482
V+G P G +G C+P G+ T G S
Sbjct: 483 WPSSVSGGYSMLP--GGCVTGSGNCSPRGEARTRLGSAS 519
>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 392 bits (1007), Expect = e-109
Identities = 215/430 (50%), Positives = 304/430 (70%), Gaps = 21/430 (4%)
Query: 5 SGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFG 64
+ FG ++ SC+ G R ++AA RG G GGF G GS G G
Sbjct: 42 ASFGSKSLSCLG--GSRS--LALSAAARRG----GGRLGGFV------GTAFGSAG--LG 85
Query: 65 YRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKV 124
+ VC P I V+VN+SLL PLN+E+DP Q V+ +E+EQIK+LN++FA+FIDKV
Sbjct: 86 PKCPSVCPPGG--IPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKV 143
Query: 125 RFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREAECVEADSGRLASELNH 182
RFLEQQN++LETK Q + C+ NLEP++EGYI L+++ E + D RL SEL +
Sbjct: 144 RFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRN 203
Query: 183 VQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRL 242
+Q+++E YKK+YE E++ R AENEFV LKKDVD AY+ K +L+A V++L EI F + L
Sbjct: 204 MQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCL 263
Query: 243 YEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCE 302
YE EI +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I +S+AEAE+ Y++K +
Sbjct: 264 YEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQ 323
Query: 303 EMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALS 362
E++ T +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + LE A+A +EQ+G+ AL
Sbjct: 324 ELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALK 383
Query: 363 DARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGI 421
DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATYR+LLE EE R+ E
Sbjct: 384 DARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYP 443
Query: 422 GAVNVCVSSS 431
+V++ V SS
Sbjct: 444 NSVSISVISS 453
>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 392 bits (1007), Expect = e-109
Identities = 215/430 (50%), Positives = 304/430 (70%), Gaps = 21/430 (4%)
Query: 5 SGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFG 64
+ FG ++ SC+ G R ++AA RG G GGF G GS G G
Sbjct: 42 ASFGSKSLSCLG--GSRS--LALSAAARRG----GGRLGGFV------GTAFGSAG--LG 85
Query: 65 YRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKV 124
+ VC P I V+VN+SLL PLN+E+DP Q V+ +E+EQIK+LN++FA+FIDKV
Sbjct: 86 PKCPSVCPPGG--IPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKV 143
Query: 125 RFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREAECVEADSGRLASELNH 182
RFLEQQN++LETK Q + C+ NLEP++EGYI L+++ E + D RL SEL +
Sbjct: 144 RFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRN 203
Query: 183 VQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRL 242
+Q+++E YKK+YE E++ R AENEFV LKKDVD AY+ K +L+A V++L EI F + L
Sbjct: 204 MQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCL 263
Query: 243 YEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCE 302
YE EI +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I +S+AEAE+ Y++K +
Sbjct: 264 YEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQ 323
Query: 303 EMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALS 362
E++ T +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + LE A+A +EQ+G+ AL
Sbjct: 324 ELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALK 383
Query: 363 DARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGI 421
DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATYR+LLE EE R+ E
Sbjct: 384 DARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYP 443
Query: 422 GAVNVCVSSS 431
+V++ V SS
Sbjct: 444 NSVSISVISS 453
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 388 bits (997), Expect = e-108
Identities = 240/530 (45%), Positives = 327/530 (61%), Gaps = 59/530 (11%)
Query: 4 GSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSC---G 60
G GFGG F S G G I+ + G + G GGFG GGF GS G
Sbjct: 50 GGGFGGGGFGSRSLVG-LGGTKSISISVAGGGGGF-GAAGGFGGRG--GGFGGGSSFGGG 105
Query: 61 RSF-----------GYRSGGVCGPS----------------PPCITTVSVNESLLTPLNL 93
F G R GG GP P I VSVN+SLL PLN+
Sbjct: 106 SGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNV 165
Query: 94 EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ--NRECCQSNL 151
++DP Q VK +E+EQIK+LN++FA+FIDKVRFLEQQN++L+TK + Q N NL
Sbjct: 166 KVDPEIQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINL 225
Query: 152 EPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVAL 211
EP+F+GYI++L+R + + A+ SELN++Q+++E YKKKYE+E++ R AEN+FV L
Sbjct: 226 EPIFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTL 285
Query: 212 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNM 271
KKDVD AY+ K +L++ V+ L QEI+FL+ LY+ EI + ++DT+V++ +DNSR+L++
Sbjct: 286 KKDVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDL 345
Query: 272 DCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 331
D IIAE+KAQY++I RS+ EAE+ Y SK EE++ TV RHG++L+ K EI+ELNR+IQR
Sbjct: 346 DSIIAEVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQR 405
Query: 332 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 391
L E+ + K Q ++ A+A +EQ+GE AL DAR KL +LE ALQ+AK+D+A L+R+YQE
Sbjct: 406 LQGEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQE 465
Query: 392 VMNSKLGLDIEIATYRRLLEGEEQRLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGS 451
+MN KL LD+EIATYR+LLEGEE R+ GDL S VT S
Sbjct: 466 LMNVKLALDVEIATYRKLLEGEECRM-------------------SGDL----SSNVTVS 502
Query: 452 VCSAPCNGNVAVSTGLCAPCGQLNTTCGGGSCGVGSCGISSLGVGSCGSS 501
V S+ + NVA G+ +++ GG S G S G GS G S
Sbjct: 503 VTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGS 552
>gi|32567786 keratin 6L [Homo sapiens]
Length = 535
Score = 388 bits (996), Expect = e-108
Identities = 233/511 (45%), Positives = 320/511 (62%), Gaps = 39/511 (7%)
Query: 5 SGFGGRAFSCISACGPRPG----RCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGS-- 58
SG GG A CGP G R ++ IS + GG GGF GS
Sbjct: 42 SGSGGGAH-----CGPGTGGFGSRSLYNLGGHKSISV--SVAGGALLGRALGGFGFGSRA 94
Query: 59 -CGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRF 117
G+ G ++ G P P I V+VN+SLLTPL++EIDP Q V+ +E+EQIK+LN++F
Sbjct: 95 FMGQGAGRQTFGPACP-PGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKF 153
Query: 118 AAFIDKVRFLEQQNKLLETKLQFYQ----NRECCQSNLEPLFEGYIETLRREAECVEADS 173
A+FIDKVRFLEQQNK+LETK Q N ++NLEPLFE Y+ ++R + ++++
Sbjct: 154 ASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSER 213
Query: 174 GRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALI 233
GRL SEL +VQ+++E +K KYE+E++ AENEFV LKKDVD AY+ + DL V L
Sbjct: 214 GRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLT 273
Query: 234 QEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEA 293
QEIDFL++LYE E+ +Q+H+S+T+VV+ +DN+R+L++D IIAE+KAQY+ I RSRAEA
Sbjct: 274 QEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEA 333
Query: 294 ESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQS 353
E+WY++K EE++ T +HG+ LR TK EI EL R IQRL E + AK Q +L+ A+A++
Sbjct: 334 EAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEA 393
Query: 354 EQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGE 413
EQ+GE AL DA+ KL +L+ AL +AK+D+ L+R+YQE+MN KL LD+EIATYR+LLE E
Sbjct: 394 EQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESE 453
Query: 414 EQRLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQ 473
E R+ G+ + S VTG+ + C G A G + G
Sbjct: 454 ESRM-------------------SGECPSAVSISVTGN-STTVCGGGAASFGGGISLGGS 493
Query: 474 LNTTCGGGSCGVGSCGISSLGVGSCGSSCRK 504
T GG S VG + V + S RK
Sbjct: 494 GGATKGGFSTNVGYSTVKGGPVSAGTSILRK 524
>gi|148612803 keratin 6 irs4 [Homo sapiens]
Length = 529
Score = 379 bits (973), Expect = e-105
Identities = 221/468 (47%), Positives = 307/468 (65%), Gaps = 32/468 (6%)
Query: 4 GSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSH--SVCGGFRA-GSCG 60
G+GFG R S S G R + R GG+G S GG RA G G
Sbjct: 42 GAGFGSR--SLYSLGGNRRISFNVAGGGVRA--------GGYGFRPGSGYGGGRASGFAG 91
Query: 61 RSFGYRSGG-----VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115
FG + G VC P I V+VN+SLL PLN+E+DP Q V+ +E+EQIK LN
Sbjct: 92 SMFGSVALGPACLSVCPPGG--IHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLND 149
Query: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREAECVEADS 173
+FA+FIDKVRFLEQQN++LETK + Q + C+ NLEP+ EGYI LR++ E + D
Sbjct: 150 KFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLSGDR 209
Query: 174 GRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALI 233
RL SEL +++++E YKK+YE E++ R TAENEFV LKKD D AY K +L+A V++L
Sbjct: 210 VRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLD 269
Query: 234 QEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEA 293
+EI FL+ LY+ EI +Q+H S+TSV++ +DN+RDL++D IIAE++ Y++I +S+AEA
Sbjct: 270 KEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEA 329
Query: 294 ESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQS 353
E+ Y++K +E++ RHG+ L+ T+ E+ ELNR+IQR+ E+ N K Q + LE A+A +
Sbjct: 330 EALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADA 389
Query: 354 EQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGE 413
EQ+G+ AL DA+ KL ELEGAL +AK+++A ++REYQE+M+ KL LD+EIATYR+LLEGE
Sbjct: 390 EQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGE 449
Query: 414 EQRLC-EGIGAVNVCVSS---------SRGGVVCGDLCVSGSRPVTGS 451
E R+ E +V++ V S S GV G V+GS T S
Sbjct: 450 ECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLGASAVAGSSGSTQS 497
>gi|194018511 keratin 77 [Homo sapiens]
Length = 578
Score = 354 bits (909), Expect = 9e-98
Identities = 213/516 (41%), Positives = 312/516 (60%), Gaps = 35/516 (6%)
Query: 4 GSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGS-------HSVCGGFRA 56
G GFG R S + G R + G C G GGFG + GGF
Sbjct: 53 GRGFGSR--SLYNLGGSRSISINLMGRSTSGF-CQGGGVGGFGGGRGFGVGSTGAGGFGG 109
Query: 57 GSCGRS-FGYRSGGVCGPSPPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIK 111
G G + FG + G+ G P C I V++N+SLL PL+LE+DP Q +K +E+EQI
Sbjct: 110 GGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIM 169
Query: 112 SLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ--NRECCQSNLEPLFEGYIETLRREAECV 169
LN++FA+FIDKVRFLEQQN++L+TK + Q N +NLEPL E YI LRR+ + +
Sbjct: 170 VLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLL 229
Query: 170 EADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANV 229
A+ R +E+ +Q+V+E YK KYE+E++ R +EN+FV LKKDVD AY+ K DLE+ V
Sbjct: 230 SAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRV 289
Query: 230 EALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRS 289
+ L E++FL+ L+ E+ +Q+HISDT+V++ +DN+R L++D II ++ QY+ I RS
Sbjct: 290 DTLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRS 349
Query: 290 RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAA 349
+ EAE+ Y++K +E++ T RHG+ L+ +K EI ELNR +QRL AE+ N K Q ++++
Sbjct: 350 KDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSL 409
Query: 350 VAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRL 409
++ +E++GE AL DA KL +LE ALQ++K+++A L+R+YQ ++ KL LD+EIATYR+L
Sbjct: 410 ISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQL 469
Query: 410 LEGEEQRLCEGIGA-VNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTG-- 466
LEGEE R+ + + V++ V +S+ + V+G GS S G G
Sbjct: 470 LEGEESRMSGELQSHVSISVQNSQ-------VSVNGGAGGGGSYGSGGYGGGSGGGYGGG 522
Query: 467 --------LCAPCGQLNTTCGGGSCGVGSCGISSLG 494
G + CGGG G G S G
Sbjct: 523 RSYRGGGARGRSGGGYGSGCGGGGGSYGGSGRSGRG 558
>gi|89357932 keratin 5b [Homo sapiens]
Length = 520
Score = 349 bits (896), Expect = 3e-96
Identities = 221/506 (43%), Positives = 304/506 (60%), Gaps = 26/506 (5%)
Query: 10 RAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGR---SFGYR 66
R FS SAC R RG R L G G GS GR FG
Sbjct: 10 RGFSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEW 69
Query: 67 SGG----VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFID 122
SGG +C P I V++N++LLTPL +EIDP Q V+ +E ++I++LN++FA+FID
Sbjct: 70 SGGPGLSLCPPGG--IQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFID 127
Query: 123 KVRFLEQQNKLLETKLQFYQNRECC--QSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
KVRFLEQQNK+LETK Q + Q LEP+FE ++ LR++ E ++ + G L +EL
Sbjct: 128 KVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAEL 187
Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
++ E YK KYEEE RAT EN+FV LKKDVD +L K +LE +EAL + + FL+
Sbjct: 188 KACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLK 247
Query: 241 RLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
L EEE+ LQ+ SDTSVV+ +DN+R L+ II E++A+Y++I S+AEAE+ Y++K
Sbjct: 248 HLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTK 307
Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
+E++ + HG+ ++ TK +I++L++ IQRL ++ EN K QN+ L+AA+ +EQ+GE A
Sbjct: 308 YQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELA 367
Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
L DA+ K+ ELE AL+ AKQ++A L+ EYQE+ ++KL LD+EIATYRRLLEGEE R+ G
Sbjct: 368 LKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRM-SG 426
Query: 421 IGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAP---CGQLNTT 477
V +SS G V G GS C G+ S G C G N
Sbjct: 427 ECTSQVTISSVGGSAVMS----GGVGGGLGSTCGL---GSGKGSPGSCCTSIVTGGSNII 479
Query: 478 CGGGSCGV-GSCGISSLGVGSCGSSC 502
G G V SC +S S GSSC
Sbjct: 480 LGSGKDPVLDSCSVSG---SSAGSSC 502
>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
Length = 469
Score = 336 bits (861), Expect = 3e-92
Identities = 196/430 (45%), Positives = 274/430 (63%), Gaps = 63/430 (14%)
Query: 5 SGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFG 64
+ FG ++ SC+ G R ++AA RG G GGF G GS G G
Sbjct: 42 ASFGSKSLSCLG--GSRS--LALSAAARRG----GGRLGGFV------GTAFGSAG--LG 85
Query: 65 YRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKV 124
+ VC P I V+VN+SLL PLN+E+DP Q V+ +E+EQIK+LN++FA+FIDKV
Sbjct: 86 PKCPSVCPPGG--IPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKV 143
Query: 125 RFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREAECVEADSGRLASELNH 182
RFLEQQN++LETK Q + C+ NLEP++EGYI L+++ E + D RL SEL +
Sbjct: 144 RFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRN 203
Query: 183 VQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRL 242
+Q+++E YKK+YE E++ R AENEFV LKKDVD AY+ K +L+A V++L EI F + L
Sbjct: 204 MQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCL 263
Query: 243 YEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCE 302
YE EI +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I +S+AEAE+ Y++KC
Sbjct: 264 YEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKCA 323
Query: 303 EMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALS 362
+ LE A+A +EQ+G+ AL
Sbjct: 324 D------------------------------------------LETAIADAEQRGDCALK 341
Query: 363 DARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGI 421
DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATYR+LLE EE R+ E
Sbjct: 342 DARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYP 401
Query: 422 GAVNVCVSSS 431
+V++ V SS
Sbjct: 402 NSVSISVISS 411
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,110,490
Number of Sequences: 37866
Number of extensions: 896180
Number of successful extensions: 6735
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 177
Number of HSP's successfully gapped in prelim test: 461
Number of HSP's that attempted gapping in prelim test: 4546
Number of HSP's gapped (non-prelim): 1741
length of query: 505
length of database: 18,247,518
effective HSP length: 107
effective length of query: 398
effective length of database: 14,195,856
effective search space: 5649950688
effective search space used: 5649950688
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.