BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|169790841 keratin 83 [Homo sapiens] (493 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|169790841 keratin 83 [Homo sapiens] 997 0.0 gi|169790853 keratin, hair, basic, 1 [Homo sapiens] 939 0.0 gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap... 872 0.0 gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap... 872 0.0 gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap... 872 0.0 gi|14318422 keratin 86 [Homo sapiens] 872 0.0 gi|4504935 keratin 85 [Homo sapiens] 783 0.0 gi|15431316 keratin, hair, basic, 4 [Homo sapiens] 540 e-153 gi|27477127 keratin 82 [Homo sapiens] 522 e-148 gi|119395754 keratin 5 [Homo sapiens] 428 e-120 gi|5031839 keratin 6A [Homo sapiens] 422 e-118 gi|153791158 keratin 75 [Homo sapiens] 420 e-117 gi|119703753 keratin 6B [Homo sapiens] 420 e-117 gi|155969697 keratin 6C [Homo sapiens] 420 e-117 gi|4504919 keratin 8 [Homo sapiens] 411 e-115 gi|109148552 keratin 3 [Homo sapiens] 405 e-113 gi|67782365 keratin 7 [Homo sapiens] 402 e-112 gi|109255249 keratin 4 [Homo sapiens] 401 e-112 gi|28173564 keratin 73 [Homo sapiens] 400 e-111 gi|15618995 keratin 71 [Homo sapiens] 399 e-111 gi|153791670 keratin 76 [Homo sapiens] 394 e-109 gi|119395750 keratin 1 [Homo sapiens] 392 e-109 gi|28372503 keratin 72 isoform 1 [Homo sapiens] 387 e-108 gi|226246663 keratin 72 isoform 1 [Homo sapiens] 387 e-108 gi|32567786 keratin 6L [Homo sapiens] 385 e-107 gi|148612803 keratin 6 irs4 [Homo sapiens] 381 e-106 gi|47132620 keratin 2 [Homo sapiens] 377 e-104 gi|194018511 keratin 77 [Homo sapiens] 350 1e-96 gi|89357932 keratin 5b [Homo sapiens] 345 5e-95 gi|226246665 keratin 72 isoform 2 [Homo sapiens] 331 8e-91 >gi|169790841 keratin 83 [Homo sapiens] Length = 493 Score = 997 bits (2578), Expect = 0.0 Identities = 493/493 (100%), Positives = 493/493 (100%) Query: 1 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR Sbjct: 1 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60 Query: 61 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS Sbjct: 61 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120 Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR Sbjct: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180 Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE Sbjct: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240 Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES Sbjct: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300 Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ Sbjct: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360 Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ Sbjct: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420 Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCGQLN 480 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCGQLN Sbjct: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCGQLN 480 Query: 481 TTCGGGSCGQGRH 493 TTCGGGSCGQGRH Sbjct: 481 TTCGGGSCGQGRH 493 >gi|169790853 keratin, hair, basic, 1 [Homo sapiens] Length = 505 Score = 939 bits (2428), Expect = 0.0 Identities = 468/491 (95%), Positives = 473/491 (96%), Gaps = 5/491 (1%) Query: 1 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60 MTCG GF FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR Sbjct: 1 MTCG-----SGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55 Query: 61 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS Sbjct: 56 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115 Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR Sbjct: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175 Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240 LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE Sbjct: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235 Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300 IDFLRRLYEEEI ILQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES Sbjct: 236 IDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295 Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ Sbjct: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355 Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ Sbjct: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415 Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCGQLN 480 RLCEG+ AVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGN+ VSTGLC PCGQLN Sbjct: 416 RLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLN 475 Query: 481 TTCGGGSCGQG 491 TTCGGGSCG G Sbjct: 476 TTCGGGSCGVG 486 >gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sapiens] Length = 486 Score = 872 bits (2253), Expect = 0.0 Identities = 445/490 (90%), Positives = 456/490 (93%), Gaps = 9/490 (1%) Query: 1 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60 MTCG CG R FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR Sbjct: 1 MTCGSY---CGGRA--FSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55 Query: 61 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS Sbjct: 56 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115 Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR Sbjct: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175 Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240 LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE Sbjct: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235 Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300 IDFLRRLYEEEIR+LQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES Sbjct: 236 IDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295 Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ Sbjct: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355 Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ Sbjct: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415 Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNLVV-STGLCKPCGQ 478 RLCEGV +VNVCVSSSRGGVVCGDLC S + PV + V S P N N+VV +T C P + Sbjct: 416 RLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR 475 Query: 479 LNTTCGGGSC 488 + GGSC Sbjct: 476 VGVC--GGSC 483 >gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sapiens] Length = 486 Score = 872 bits (2253), Expect = 0.0 Identities = 445/490 (90%), Positives = 456/490 (93%), Gaps = 9/490 (1%) Query: 1 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60 MTCG CG R FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR Sbjct: 1 MTCGSY---CGGRA--FSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55 Query: 61 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS Sbjct: 56 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115 Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR Sbjct: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175 Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240 LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE Sbjct: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235 Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300 IDFLRRLYEEEIR+LQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES Sbjct: 236 IDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295 Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ Sbjct: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355 Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ Sbjct: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415 Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNLVV-STGLCKPCGQ 478 RLCEGV +VNVCVSSSRGGVVCGDLC S + PV + V S P N N+VV +T C P + Sbjct: 416 RLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR 475 Query: 479 LNTTCGGGSC 488 + GGSC Sbjct: 476 VGVC--GGSC 483 >gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sapiens] Length = 486 Score = 872 bits (2253), Expect = 0.0 Identities = 445/490 (90%), Positives = 456/490 (93%), Gaps = 9/490 (1%) Query: 1 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60 MTCG CG R FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR Sbjct: 1 MTCGSY---CGGRA--FSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55 Query: 61 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS Sbjct: 56 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115 Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR Sbjct: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175 Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240 LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE Sbjct: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235 Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300 IDFLRRLYEEEIR+LQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES Sbjct: 236 IDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295 Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ Sbjct: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355 Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ Sbjct: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415 Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNLVV-STGLCKPCGQ 478 RLCEGV +VNVCVSSSRGGVVCGDLC S + PV + V S P N N+VV +T C P + Sbjct: 416 RLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR 475 Query: 479 LNTTCGGGSC 488 + GGSC Sbjct: 476 VGVC--GGSC 483 >gi|14318422 keratin 86 [Homo sapiens] Length = 486 Score = 872 bits (2253), Expect = 0.0 Identities = 445/490 (90%), Positives = 456/490 (93%), Gaps = 9/490 (1%) Query: 1 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60 MTCG CG R FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR Sbjct: 1 MTCGSY---CGGRA--FSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55 Query: 61 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS Sbjct: 56 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115 Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR Sbjct: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175 Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240 LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE Sbjct: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235 Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300 IDFLRRLYEEEIR+LQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES Sbjct: 236 IDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295 Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ Sbjct: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355 Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ Sbjct: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415 Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNLVV-STGLCKPCGQ 478 RLCEGV +VNVCVSSSRGGVVCGDLC S + PV + V S P N N+VV +T C P + Sbjct: 416 RLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR 475 Query: 479 LNTTCGGGSC 488 + GGSC Sbjct: 476 VGVC--GGSC 483 >gi|4504935 keratin 85 [Homo sapiens] Length = 507 Score = 783 bits (2023), Expect = 0.0 Identities = 408/500 (81%), Positives = 438/500 (87%), Gaps = 20/500 (4%) Query: 7 SIGCGFRPGNFSCVSACGPRP-SRCCITAAPYRGISCYRGLTGGFGSHSVC--------- 56 S GCG NFS SA P+ +RCCI+AAPYRG+SCYRGLTG FGS S+C Sbjct: 9 SSGCGVTR-NFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTG-FGSRSLCNLGSCGPRI 66 Query: 57 --GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ 114 GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ Sbjct: 67 AVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ 126 Query: 115 IKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECV 174 IKSLNSRFAAFIDKVRFLEQQNKLLETK QFYQN+ CC+SNLEPLF+GYIETLRREAECV Sbjct: 127 IKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETLRREAECV 186 Query: 175 EADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANV 234 EADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFV LKKDVDCAYLRKSDLEANV Sbjct: 187 EADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANV 246 Query: 235 EALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRS 294 EAL++E FLRRLYEEEIR+LQ+HISDTSV+VK+DNSRDLNMDCI+AEIKAQYDD+A+RS Sbjct: 247 EALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRS 306 Query: 295 RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAA 354 RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE+ENAKCQ +KLEAA Sbjct: 307 RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAA 366 Query: 355 VAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRL 414 VA++EQQGEAALSDARCKLAELEGALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRL Sbjct: 367 VAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRL 426 Query: 415 LEGEEQRLCEGVEAVNVCVSSSRGGVVCGDLCVSGS--RPVTGSVCSAPCNGNLVVSTGL 472 LEGEE RLCEGV +VNVCVSSSRGGV CG L S + R +T S SA VV+ Sbjct: 427 LEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTPGRQIT-SGPSAIGGSITVVAPDS 485 Query: 473 CKPCGQLNTTCGGGSCGQGR 492 C PC +++ SCG R Sbjct: 486 CAPCQPRSSSF---SCGSSR 502 >gi|15431316 keratin, hair, basic, 4 [Homo sapiens] Length = 600 Score = 540 bits (1391), Expect = e-153 Identities = 290/468 (61%), Positives = 360/468 (76%), Gaps = 11/468 (2%) Query: 20 VSACGPRPSRCCIT--AAPYRGISCYRGLTGGFGSHSVCG-GFRAGSC------GRSFGY 70 ++A G RP C + A G RG+ G + S G GF AGS G FGY Sbjct: 65 IAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGY 124 Query: 71 RSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVR 130 R GGV P+ P IT V+VN+SLLTPLNLEIDPNAQ VK++EKEQIK+LN++FA+FIDKVR Sbjct: 125 RVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVR 184 Query: 131 FLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQE 190 FLEQQNKLLETK F Q ++C +SNLEPLF YI LRR+ E + +D RL +E NH+Q+ Sbjct: 185 FLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQD 244 Query: 191 VLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 250 VLEG+KKKYEEEV RA AENEFVALKKDVD A++ KSDLEANV+ L QEIDFL+ LY E Sbjct: 245 VLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYME 304 Query: 251 EIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMK 310 EI++LQSHIS+TSV+VK+DNSRDLN+D I+AE+KAQY+++A RSRA+AE+WY++K EEM+ Sbjct: 305 EIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQ 364 Query: 311 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 370 T +H + LR + EINEL R+IQRL AE+E+AK Q +KLEAAVA++EQQGEA LSDA+ Sbjct: 365 VTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAK 424 Query: 371 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVEAVN 430 CKLA+LE ALQ+AKQDMA + EYQE+MN+KLGLDIEIATYRRLLEGEE RLCEGV VN Sbjct: 425 CKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVN 484 Query: 431 VCVSSSRGGVVCG-DLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCG 477 + VSSSRGG+VCG + V+GS G V + + ++ ++G+ CG Sbjct: 485 ISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSG-SSSVCATSGVLASCG 531 >gi|27477127 keratin 82 [Homo sapiens] Length = 513 Score = 522 bits (1345), Expect = e-148 Identities = 296/503 (58%), Positives = 356/503 (70%), Gaps = 34/503 (6%) Query: 12 FRPGN------FSCVSACGPRP-SRCCITAAPYRGISCYRGLT--GGFGSHSVCG-GFR- 60 F+PG+ FS SA PR + ++ P R RGL G GS S+C GF Sbjct: 6 FQPGSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRP-GGGRGLRALGCLGSRSLCNVGFGR 64 Query: 61 ---AGSCGRS---FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ 114 A CG + FGYR G CGPS CIT V++NESLL PL LEIDP Q VK++EKEQ Sbjct: 65 PRVASRCGGTLPGFGYRLGATCGPSA-CITPVTINESLLVPLALEIDPTVQRVKRDEKEQ 123 Query: 115 IKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECV 174 IK LN+RFA+FI+KVRFLEQ+NKLLETK F Q + CCQ+N+EP+F GYI LRR+ +CV Sbjct: 124 IKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCV 183 Query: 175 EADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANV 234 D RL SEL +Q LEGYKKKYEEE++LR ENEFVALKKDVD A+L K+DLE N Sbjct: 184 SGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNA 243 Query: 235 EALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRS 294 EAL+QEIDFL+ LYEEEI +LQS IS+TSV+VK+DNSR+L++D I+AEIKAQYDDIA+RS Sbjct: 244 EALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRS 303 Query: 295 RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAA 354 +AEAE+WY+ + EE++ T H + LR K EI E+N++IQRL E EN K Q KLE A Sbjct: 304 KAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGA 363 Query: 355 VAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRL 414 +A++EQQGEAAL+DA+CKLA LE ALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRL Sbjct: 364 IAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRL 423 Query: 415 LEGEEQRLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSV-----CSAPCNGNLVVS 469 LEGEE RLCEG+ VN+ VSSS+G + VS TG + CS G L V Sbjct: 424 LEGEEHRLCEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGELYVP 483 Query: 470 TGLCKPCGQLNTTCGGGSCGQGR 492 C+P G L SCG GR Sbjct: 484 ---CEPQGLL-------SCGSGR 496 >gi|119395754 keratin 5 [Homo sapiens] Length = 590 Score = 428 bits (1101), Expect = e-120 Identities = 229/401 (57%), Positives = 300/401 (74%), Gaps = 9/401 (2%) Query: 45 GLTGGFGSHSVCGGFRAGSCGRSFGYR-SGGVCGPS-PPC----ITTVSVNESLLTPLNL 98 G GG GS GG G G G GG GP P C I V+VN+SLLTPLNL Sbjct: 96 GFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 155 Query: 99 EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 156 +IDP+ Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK Q + + + NL Sbjct: 156 QIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 215 Query: 157 EPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVAL 216 EPLF YI LRR+ + + + GRL SEL ++Q+++E +K KYE+E+ R TAENEFV L Sbjct: 216 EPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVML 275 Query: 217 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNM 276 KKDVD AY+ K +LEA V+AL+ EI+F++ ++ E+ +Q+H+SDTSVV+ +DN+R+L++ Sbjct: 276 KKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDL 335 Query: 277 DCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 336 D I+AE+KAQY++IA RSR EAESWY++K EE++ T RHG+ LR TK EI+E+NRMIQR Sbjct: 336 DSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQR 395 Query: 337 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 396 L AE++N K Q + L+ A+A +EQ+GE AL DAR KLAELE ALQKAKQDMA L+REYQE Sbjct: 396 LRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQE 455 Query: 397 VMNSKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSSS 436 +MN+KL LD+EIATYR+LLEGEE RL EGV VN+ V +S Sbjct: 456 LMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTS 496 >gi|5031839 keratin 6A [Homo sapiens] Length = 564 Score = 422 bits (1085), Expect = e-118 Identities = 250/516 (48%), Positives = 331/516 (64%), Gaps = 33/516 (6%) Query: 4 GFNSIGCGFRPGNFSCVSACGPRP--SRCCITAAPYRGISCYRG---LTGGFGSHSVCGG 58 GF+S+ G+ ACG SR + IS G ++GG+GS + G Sbjct: 32 GFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAG-GS 90 Query: 59 FRAGSCGRSFGYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNL 98 + G G FG+ +GG GP P C I V+VN+SLLTPLNL Sbjct: 91 YGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 150 Query: 99 EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 156 +IDP Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK Q + + + NL Sbjct: 151 QIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNL 210 Query: 157 EPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVAL 216 EPLF YI LRR+ + + + GRL SEL +Q+++E +K KYE+E+ R AENEFV L Sbjct: 211 EPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTL 270 Query: 217 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNM 276 KKDVD AY+ K +L+A + L EI+FLR LY+ E+ +Q+HISDTSVV+ +DN+R+L++ Sbjct: 271 KKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDL 330 Query: 277 DCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 336 D I+AE+KAQY++IA RSRAEAESWY++K EE++ T RHG+ LR TK+EI E+NRMIQR Sbjct: 331 DSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQR 390 Query: 337 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 396 L +E+++ K Q + L+AA+A +EQ+GE AL DA+ KL LE ALQKAKQD+A L++EYQE Sbjct: 391 LRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQE 450 Query: 397 VMNSKLGLDIEIATYRRLLEGEEQRL-CEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTG 455 +MN KL LD+EIATYR+LLEGEE RL EGV VN+ V S G GS G Sbjct: 451 LMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLG 510 Query: 456 SVCSAPCNGNLVVSTGLCKPCGQL----NTTCGGGS 487 S L V G G+ ++ GGGS Sbjct: 511 GGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGS 546 >gi|153791158 keratin 75 [Homo sapiens] Length = 551 Score = 420 bits (1080), Expect = e-117 Identities = 244/462 (52%), Positives = 315/462 (68%), Gaps = 32/462 (6%) Query: 39 GISCYRGLTGGFGSH-SVCGGFRAGSCGRSFGYRSGGVCGPS-PPC----ITTVSVNESL 92 G SC G G + V GF G G GG GPS P C I V+VN+SL Sbjct: 77 GSSCRSGFGGRASNRFGVNSGFGYG------GGVGGGFSGPSFPVCPPGGIQEVTVNQSL 130 Query: 93 LTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--E 150 LTPL+L+IDP Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK Q + Sbjct: 131 LTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSR 190 Query: 151 CCQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAE 210 + NLEPLF Y LRR+ E + + GRL +EL ++Q+V+E +K +YE+E+ R AE Sbjct: 191 TVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAE 250 Query: 211 NEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDN 270 NEFVALKKDVD AY+ K +LEA V++L +EI+F+ +++ E+ LQ+ + DTSVV+ +DN Sbjct: 251 NEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDN 310 Query: 271 SRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINEL 330 +R+L++D I+AE+KAQY+DIA RSRAEAESWY++K EE++ T RHG+ LR TK+EI+E+ Sbjct: 311 NRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEM 370 Query: 331 NRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACL 390 NRMIQRL AE+++ K Q S L+ A+A +EQ+GE AL DAR KL +LE ALQKAKQDMA L Sbjct: 371 NRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARL 430 Query: 391 IREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSSSRGGVVCGDLCVSG 449 +REYQE+MN KL LD+EIATYR+LLEGEE RL EGV VN+ V +S G SG Sbjct: 431 LREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYG----SG 486 Query: 450 SRPVTGSVCSAPCNGNLVVSTGLCKPCGQLNTTCGGGSCGQG 491 S+ GNL GL G TT GG S G G Sbjct: 487 ---------SSIGGGNL----GLGGGSGYSFTTSGGHSLGAG 515 >gi|119703753 keratin 6B [Homo sapiens] Length = 564 Score = 420 bits (1080), Expect = e-117 Identities = 250/516 (48%), Positives = 331/516 (64%), Gaps = 33/516 (6%) Query: 4 GFNSIGCGFRPGNFSCVSACGPRP--SRCCITAAPYRGISCYRG---LTGGFGSHSVCGG 58 GF+SI G+ ACG SR + IS G ++GG+GS + G Sbjct: 32 GFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAG-GS 90 Query: 59 FRAGSCGRSFGYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNL 98 + G G FG+ +GG GP P C I V+VN+SLLTPLNL Sbjct: 91 YGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 150 Query: 99 EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 156 +IDP Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK Q + + + NL Sbjct: 151 QIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 210 Query: 157 EPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVAL 216 EPLF YI LRR+ + + + GRL SEL ++Q+++E K KYE+E+ R AENEFV L Sbjct: 211 EPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTL 270 Query: 217 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNM 276 KKDVD AY+ K +L+A + L EI+FLR LY+ E+ +Q+HISDTSVV+ +DN+R+L++ Sbjct: 271 KKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDL 330 Query: 277 DCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 336 D I+AE+KAQY++IA RSRAEAESWY++K EE++ T RHG+ LR TK+EI E+NRMIQR Sbjct: 331 DSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEIAEINRMIQR 390 Query: 337 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 396 L +E+++ K Q + L+AA+A +EQ+GE AL DA+ KL LE ALQKAKQD+A L++EYQE Sbjct: 391 LRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQE 450 Query: 397 VMNSKLGLDIEIATYRRLLEGEEQRL-CEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTG 455 +MN KL LD+EIATYR+LLEGEE RL EGV VN+ V S G GS G Sbjct: 451 LMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLG 510 Query: 456 SVCSAPCNGNLVVSTGLCKPCGQLN----TTCGGGS 487 S L V G G+ ++ GGGS Sbjct: 511 GGSSYSYGSGLGVGGGFSSSSGRATGGGLSSVGGGS 546 >gi|155969697 keratin 6C [Homo sapiens] Length = 564 Score = 420 bits (1079), Expect = e-117 Identities = 250/516 (48%), Positives = 331/516 (64%), Gaps = 33/516 (6%) Query: 4 GFNSIGCGFRPGNFSCVSACGPRP--SRCCITAAPYRGISCYRG---LTGGFGSHSVCGG 58 GF+SI G+ ACG SR + IS G ++GG+GS + G Sbjct: 32 GFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAG-GS 90 Query: 59 FRAGSCGRSFGYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNL 98 + G G FG+ +GG GP P C I V+VN+SLLTPLNL Sbjct: 91 YGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 150 Query: 99 EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 156 +IDP Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK Q + + + NL Sbjct: 151 QIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 210 Query: 157 EPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVAL 216 EPLF YI LRR+ + + + GRL SEL ++Q+++E K KYE+E+ R AENEFV L Sbjct: 211 EPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTL 270 Query: 217 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNM 276 KKDVD AY+ K +L+A + L EI+FLR LY+ E+ +Q+HISDTSVV+ +DN+R+L++ Sbjct: 271 KKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDL 330 Query: 277 DCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 336 D I+AE+KAQY++IA RSRAEAESWY++K EE++ T RHG+ LR TK+EI E+NRMIQR Sbjct: 331 DSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQR 390 Query: 337 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 396 L +E+++ K Q + L+AA+A +EQ+GE AL DA+ KL LE ALQKAKQD+A L++EYQE Sbjct: 391 LRSEIDHVKKQCASLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQE 450 Query: 397 VMNSKLGLDIEIATYRRLLEGEEQRL-CEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTG 455 +MN KL LD+EIATYR+LLEGEE RL EGV VNV V S G GS G Sbjct: 451 LMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNVSVVQSTISSGYGGASGVGSGLGLG 510 Query: 456 SVCSAPCNGNLVVSTGLCKPCGQL----NTTCGGGS 487 S L + G G+ ++ GGGS Sbjct: 511 GGSSYSYGSGLGIGGGFSSSSGRAIGGGLSSVGGGS 546 >gi|4504919 keratin 8 [Homo sapiens] Length = 483 Score = 411 bits (1056), Expect = e-115 Identities = 218/396 (55%), Positives = 286/396 (72%), Gaps = 1/396 (0%) Query: 44 RGLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPC-ITTVSVNESLLTPLNLEIDP 102 R T G GS F G GG G S IT V+VN+SLL+PL LE+DP Sbjct: 23 RSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGGITAVTVNQSLLSPLVLEVDP 82 Query: 103 NAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAG 162 N Q V+ +EKEQIK+LN++FA+FIDKVRFLEQQNK+LETK Q ++ +SN++ +F Sbjct: 83 NIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKTARSNMDNMFES 142 Query: 163 YIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDC 222 YI LRR+ E + + +L +EL ++Q ++E +K KYE+E+ R ENEFV +KKDVD Sbjct: 143 YINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDE 202 Query: 223 AYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAE 282 AY+ K +LE+ +E L EI+FLR+LYEEEIR LQS ISDTSVV+ +DNSR L+MD I+AE Sbjct: 203 AYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAE 262 Query: 283 IKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVE 342 +KAQY+DIA RSRAEAES Y+ K EE+++ +HG+ LRRTK EI+E+NR I RL AE+E Sbjct: 263 VKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIE 322 Query: 343 NAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKL 402 K Q + LEAA+A +EQ+GE A+ DA KL+ELE ALQ+AKQDMA +REYQE+MN KL Sbjct: 323 GLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLREYQELMNVKL 382 Query: 403 GLDIEIATYRRLLEGEEQRLCEGVEAVNVCVSSSRG 438 LDIEIATYR+LLEGEE RL G++ +++ ++ G Sbjct: 383 ALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSG 418 >gi|109148552 keratin 3 [Homo sapiens] Length = 628 Score = 405 bits (1041), Expect = e-113 Identities = 219/397 (55%), Positives = 286/397 (72%), Gaps = 11/397 (2%) Query: 45 GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNA 104 G GGFG GG GS G G+ GG P I V++N+SLL PLN+EIDP Sbjct: 138 GGPGGFGGSGGFGG--PGSLGSPGGFGPGGF----PGGIQEVTINQSLLQPLNVEIDPQI 191 Query: 105 QCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ----SNLEPLF 160 VK +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK Q + +NLEPLF Sbjct: 192 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLF 251 Query: 161 AGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDV 220 +I LR + + + GRL SEL ++++++E +KKKYE+E+ R AENEFV LKKDV Sbjct: 252 ENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDV 311 Query: 221 DCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIV 280 D AY+ K +L+A V+ALI EIDFLR LY+ E+ +QSHISDTSVV+ +DN+R L++D I+ Sbjct: 312 DSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSII 371 Query: 281 AEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE 340 AE++AQY+DIA RS+AEAE+ Y++K E++ T RHG+ LR TK EI ELNRMIQRL AE Sbjct: 372 AEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAE 431 Query: 341 VENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNS 400 +E K QN+ L+ A+A++EQ GE AL DA KL EL+ ALQ+AK D+A L+R+YQE+MN Sbjct: 432 IEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNV 491 Query: 401 KLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSSS 436 KL LD+EIATYR+LLEGEE R+ E AV++ V SS Sbjct: 492 KLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSS 528 >gi|67782365 keratin 7 [Homo sapiens] Length = 469 Score = 402 bits (1032), Expect = e-112 Identities = 220/398 (55%), Positives = 287/398 (72%), Gaps = 6/398 (1%) Query: 48 GGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 107 GG GS S+ G G+ RS GP I V++N+SLL PL L+ DP+ Q V Sbjct: 32 GGLGSSSLYG---LGASRPRVAVRSA-YGGPVGAGIREVTINQSLLAPLRLDADPSLQRV 87 Query: 108 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEP-LFAGYIET 166 +QEE EQIK+LN++FA+FIDKVRFLEQQNKLLETK Q ++ +S+ P +F I Sbjct: 88 RQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRLPDIFEAQIAG 147 Query: 167 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLR 226 LR + E ++ D GRL +EL +Q+V+E +K KYE+E+ R AENEFV LKKDVD AY+ Sbjct: 148 LRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMS 207 Query: 227 KSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQ 286 K +LEA V+AL EI+FLR L E E+ LQS ISDTSVV+ +DNSR L++D I+AE+KAQ Sbjct: 208 KVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQ 267 Query: 287 YDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 346 Y+++A SRAEAE+WY++K E ++A +HG+ LR T+ EI+E+NR IQRL AE++N K Sbjct: 268 YEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKN 327 Query: 347 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 406 Q +KLEAA+A++E++GE AL DAR K ELE ALQ+ KQDMA +REYQE+M+ KL LDI Sbjct: 328 QRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDI 387 Query: 407 EIATYRRLLEGEEQRLC-EGVEAVNVCVSSSRGGVVCG 443 EIATYR+LLEGEE RL +GV AVN+ V +S GG G Sbjct: 388 EIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSG 425 >gi|109255249 keratin 4 [Homo sapiens] Length = 594 Score = 401 bits (1030), Expect = e-112 Identities = 227/463 (49%), Positives = 310/463 (66%), Gaps = 21/463 (4%) Query: 2 TCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRG-----LTGGFGSHSVC 56 +CG +G G R G FS VS G RC R + RG ++ C Sbjct: 90 SCGSAIVGGGKR-GAFSSVSMSGGA-GRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGAC 147 Query: 57 ----GGFRAGSCGRSFGYRSGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCV 107 GGF G G FG G GP P C I V++N+SLLTPL++EIDP Q V Sbjct: 148 FGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDPEIQKV 207 Query: 108 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFAGYIE 165 + EE+EQIK LN++FA+FIDKV+FLEQQNK+LETK Q + S NLEPLF Y+ Sbjct: 208 RTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFETYLS 267 Query: 166 TLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYL 225 LR++ + + D GRL SEL +Q+ +E +K KYEEE+ R AEN+FV LKKDVD AYL Sbjct: 268 VLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYL 327 Query: 226 RKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKA 285 K +LEA V++L EI+FL+ LY+ E+ +Q+H+SDTSVV+ +DN+R+L++D I+AE++A Sbjct: 328 NKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRA 387 Query: 286 QYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAK 345 QY++IA RS+AEAE+ Y++K ++++ +V +HG+ L+ TK EI ELNRMIQRL AE+EN K Sbjct: 388 QYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIK 447 Query: 346 CQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLD 405 Q L+ +VA +EQ+GE AL DA K ELE ALQ+AK+++A ++REYQE+M+ KL LD Sbjct: 448 KQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVKLALD 507 Query: 406 IEIATYRRLLEGEEQRL---CEGVEAVNVCVSSSRGGVVCGDL 445 IEIATYR+LLEGEE R+ C+ +++V S+ G + G L Sbjct: 508 IEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGL 550 >gi|28173564 keratin 73 [Homo sapiens] Length = 540 Score = 400 bits (1027), Expect = e-111 Identities = 223/459 (48%), Positives = 308/459 (67%), Gaps = 21/459 (4%) Query: 45 GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEID 101 G GG+G G +G G FG + G PS P I V++N+SLL PLN+E+D Sbjct: 66 GWAGGYGFGR---GRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELD 122 Query: 102 PNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPL 159 P Q V+ +E+EQIK LN++FA+FIDKVRFLEQQN++LETK + Q + C++NLEP+ Sbjct: 123 PEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPI 182 Query: 160 FAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKD 219 GYI LR++ E + D RL SEL V+EV+E YKK+YEEE+ R TAENEFV LKKD Sbjct: 183 LEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKD 242 Query: 220 VDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCI 279 VD AY K +L+A V+AL EI F + LYE E +QSHISDTS+++ +DN+R+L++D I Sbjct: 243 VDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSI 302 Query: 280 VAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTA 339 +AE++AQY++IA +S+AEAE+ Y++K +E++ RHG+ L+ TK EI+EL R+IQRL + Sbjct: 303 IAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRS 362 Query: 340 EVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMN 399 E+E+ K Q + LE A+A +EQ+G+ AL DAR KL ELEGALQ+AK+++A ++REYQE+++ Sbjct: 363 EIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLS 422 Query: 400 SKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSSSRGGVVCGDLCVSG--------- 449 KL LDIEIATYR+LLEGEE R+ E +V++ V +S + G G Sbjct: 423 VKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTYGY 482 Query: 450 -SRPVTGSVCSAPCNGNLVVSTGLCKPCGQLNTTCGGGS 487 V+G P G V +G C P G+ T G S Sbjct: 483 WPSSVSGGYSMLP--GGCVTGSGNCSPRGEARTRLGSAS 519 >gi|15618995 keratin 71 [Homo sapiens] Length = 523 Score = 399 bits (1024), Expect = e-111 Identities = 224/447 (50%), Positives = 307/447 (68%), Gaps = 32/447 (7%) Query: 44 RGLTGGFGSHSV--CGGFR----AGSCGRSFGY-----RSGGVCGP-------SPPCITT 85 +GL+GGFGS S+ GG R A G+S GY R+ G G P C T Sbjct: 37 KGLSGGFGSRSLYSLGGVRSLNVASGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTV 96 Query: 86 --------VSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNK 137 V+VNESLL PLN+E+DP Q V+ +E+EQIK+LN++FA+FIDKVRFLEQQN+ Sbjct: 97 CPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQ 156 Query: 138 LLETKLQFYQNREC--CQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGY 195 +LETK + Q + C++NLEP+ GYI LR++ E + D RL SEL +V++V+E Y Sbjct: 157 VLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDY 216 Query: 196 KKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRIL 255 KK+YEEE+ R AENEFV LKKDVD AY K +L+A VE++ QEI F R L+E EI + Sbjct: 217 KKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQI 276 Query: 256 QSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIR 315 QSHISD SV++ +DN+R+L++D I+ E++ QY++IA +S+AEAE+ Y++K +E++ R Sbjct: 277 QSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGR 336 Query: 316 HGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAE 375 HG+ L+ TK EI+EL R+IQR+ +E+EN K Q S LE A+A +EQ+G+ AL DAR KL E Sbjct: 337 HGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDE 396 Query: 376 LEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNV-CV 433 LEGAL +AK+++A ++REYQE+M+ KL LD+EIATYR+LLE EE R+ E V++ + Sbjct: 397 LEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISII 456 Query: 434 SSSRGGVVCG--DLCVSGSRPVTGSVC 458 SS+ GG V G VSG S C Sbjct: 457 SSTSGGSVYGFRPSMVSGGYVANSSNC 483 >gi|153791670 keratin 76 [Homo sapiens] Length = 638 Score = 394 bits (1012), Expect = e-109 Identities = 228/464 (49%), Positives = 306/464 (65%), Gaps = 25/464 (5%) Query: 45 GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNA 104 G GGFG V GG GS G G+ GG P I V VN+SLL PLN+EIDP Sbjct: 123 GGAGGFGGPGVFGG--PGSFGGPGGFGPGGF----PGGIQEVIVNQSLLQPLNVEIDPQI 176 Query: 105 QCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ--SNLEPLFAG 162 VK +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK + Q + S+LEP F Sbjct: 177 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFES 236 Query: 163 YIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDC 222 YI L ++ + + + G L EL +Q+++E +KKKYE+E+ R AENEFV LKKDVD Sbjct: 237 YISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDA 296 Query: 223 AYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAE 282 A++ K +L+A V++L E+ FLR LYE E+ +QSH SDTSVV+ +DN+R L++ I+AE Sbjct: 297 AFMNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAE 356 Query: 283 IKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVE 342 ++AQY++IA RS++EAE+ Y++K E++ T RHG+ LR TK EI ELNRMIQRL AE+E Sbjct: 357 VRAQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIE 416 Query: 343 NAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKL 402 N K QN+ L+ A+A++EQ+GE AL DA KL +L+ ALQKAK D+A L+R+YQE+MN KL Sbjct: 417 NVKKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKL 476 Query: 403 GLDIEIATYRRLLEGEEQRLCEGVEAVNVCVS-------------SSRGGVVCGDLCVSG 449 LD+EIATYR+LLEGEE R+ ++ VC+S SSRG V G + SG Sbjct: 477 ALDVEIATYRKLLEGEECRMSGECQSA-VCISVVSNVTSTSGSSGSSRG--VFGGVSGSG 533 Query: 450 SRPVTGSVCSAPCNGNLVVSTGLCKPCGQLNTTCGGGSCGQGRH 493 S G S+ +G VS G G +++ GG G + Sbjct: 534 SGGYKGGSSSSSSSG-YGVSGGSGSGYGGVSSGSTGGRGSSGSY 576 >gi|119395750 keratin 1 [Homo sapiens] Length = 644 Score = 392 bits (1008), Expect = e-109 Identities = 223/448 (49%), Positives = 308/448 (68%), Gaps = 9/448 (2%) Query: 48 GGFGSHSVCGGFRAGSCGRS-FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQC 106 GGFGS GGF G G +G G VC P I V++N+SLL PLN+EIDP Q Sbjct: 120 GGFGSGG--GGFGGGGFGGGGYGGGYGPVCPPGG--IQEVTINQSLLQPLNVEIDPEIQK 175 Query: 107 VKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFAGYI 164 VK E+EQIKSLN++FA+FIDKVRFLEQQN++L+TK + Q + NLEP F +I Sbjct: 176 VKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFI 235 Query: 165 ETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAY 224 LRR + +++D RL SEL ++Q+++E Y+ KYE+E+ R AENEFV +KKDVD AY Sbjct: 236 NNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAY 295 Query: 225 LRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIK 284 + K DL+A ++ L QEIDFL LY+ E+ +Q+ IS+T+V++ +DN+R L++D I+AE+K Sbjct: 296 MTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVK 355 Query: 285 AQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENA 344 AQY+DIA +S+AEAES Y+SK EE++ T RHG+++R +K EI+ELNR+IQRL +E++N Sbjct: 356 AQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNV 415 Query: 345 KCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGL 404 K Q S L+ +++ +EQ+GE AL DA+ KL +LE ALQ+AK+D+A L+R+YQE+MN+KL L Sbjct: 416 KKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLAL 475 Query: 405 DIEIATYRRLLEGEEQRLCEGVEAVNVCVS-SSRGGVVCGDLCVSGSRPVTGSVCSAPCN 463 D+EIATYR LLEGEE R+ G A NV VS S+ + G G GS S+ + Sbjct: 476 DLEIATYRTLLEGEESRM-SGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGS 534 Query: 464 GNLVVSTGLCKPCGQLNTTCGGGSCGQG 491 G +G G+ + GG S G G Sbjct: 535 GGGSYGSGGGGGGGRGSYGSGGSSYGSG 562 >gi|28372503 keratin 72 isoform 1 [Homo sapiens] Length = 511 Score = 387 bits (995), Expect = e-108 Identities = 202/386 (52%), Positives = 285/386 (73%), Gaps = 6/386 (1%) Query: 57 GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 113 GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+ +E+E Sbjct: 68 GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127 Query: 114 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFAGYIETLRREA 171 QIK+LN++FA+FIDKVRFLEQQN++LETK Q + C+ NLEP++ GYI L+++ Sbjct: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187 Query: 172 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLE 231 E + D RL SEL ++Q+++E YKK+YE E+ R AENEFV LKKDVD AY+ K +L+ Sbjct: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247 Query: 232 ANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIA 291 A V++L EI F + LYE EI +QSHISDTS+V+ +DN+RDL++D I+AE++AQY++IA Sbjct: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307 Query: 292 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 351 +S+AEAE+ Y++K +E++ T +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + L Sbjct: 308 LKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADL 367 Query: 352 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 411 E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY Sbjct: 368 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 427 Query: 412 RRLLEGEEQRLC-EGVEAVNVCVSSS 436 R+LLE EE R+ E +V++ V SS Sbjct: 428 RKLLESEECRMSGEYPNSVSISVISS 453 >gi|226246663 keratin 72 isoform 1 [Homo sapiens] Length = 511 Score = 387 bits (995), Expect = e-108 Identities = 202/386 (52%), Positives = 285/386 (73%), Gaps = 6/386 (1%) Query: 57 GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 113 GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+ +E+E Sbjct: 68 GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127 Query: 114 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFAGYIETLRREA 171 QIK+LN++FA+FIDKVRFLEQQN++LETK Q + C+ NLEP++ GYI L+++ Sbjct: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187 Query: 172 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLE 231 E + D RL SEL ++Q+++E YKK+YE E+ R AENEFV LKKDVD AY+ K +L+ Sbjct: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247 Query: 232 ANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIA 291 A V++L EI F + LYE EI +QSHISDTS+V+ +DN+RDL++D I+AE++AQY++IA Sbjct: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307 Query: 292 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 351 +S+AEAE+ Y++K +E++ T +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + L Sbjct: 308 LKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADL 367 Query: 352 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 411 E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY Sbjct: 368 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 427 Query: 412 RRLLEGEEQRLC-EGVEAVNVCVSSS 436 R+LLE EE R+ E +V++ V SS Sbjct: 428 RKLLESEECRMSGEYPNSVSISVISS 453 >gi|32567786 keratin 6L [Homo sapiens] Length = 535 Score = 385 bits (988), Expect = e-107 Identities = 215/434 (49%), Positives = 294/434 (67%), Gaps = 31/434 (7%) Query: 39 GISCYRGLTGGFGSHS-------------VCGGFRAGSCGRSFGYRSGGVCGPS------ 79 G C G TGGFGS S V GG G FG+ S G Sbjct: 47 GAHCGPG-TGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTF 105 Query: 80 -PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQ 134 P C I V+VN+SLLTPL++EIDP Q V+ +E+EQIK+LN++FA+FIDKVRFLEQ Sbjct: 106 GPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQ 165 Query: 135 QNKLLETKLQFYQ----NRECCQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQE 190 QNK+LETK Q N ++NLEPLF Y+ ++R + ++++ GRL SEL +VQ+ Sbjct: 166 QNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQD 225 Query: 191 VLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 250 ++E +K KYE+E+ AENEFV LKKDVD AY+ + DL V L QEIDFL++LYE Sbjct: 226 LVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEM 285 Query: 251 EIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMK 310 E+ +Q+H+S+T+VV+ +DN+R+L++D I+AE+KAQY+ IA RSRAEAE+WY++K EE++ Sbjct: 286 ELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQ 345 Query: 311 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 370 T +HG+ LR TK EI EL R IQRL E + AK Q +L+ A+A++EQ+GE AL DA+ Sbjct: 346 VTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQ 405 Query: 371 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVEAV 429 KL +L+ AL +AK+D+ L+R+YQE+MN KL LD+EIATYR+LLE EE R+ E AV Sbjct: 406 KKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAV 465 Query: 430 NVCVSSSRGGVVCG 443 ++ V+ + VCG Sbjct: 466 SISVTGN-STTVCG 478 >gi|148612803 keratin 6 irs4 [Homo sapiens] Length = 529 Score = 381 bits (979), Expect = e-106 Identities = 222/488 (45%), Positives = 311/488 (63%), Gaps = 50/488 (10%) Query: 15 GNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVC--------------GGFR 60 GNFS SA PR + + + G RG GFGS S+ GG R Sbjct: 14 GNFSVHSAVVPRKAVGSLASYCAAG----RGAGAGFGSRSLYSLGGNRRISFNVAGGGVR 69 Query: 61 AGSCG--RSFGY---RSGGVCGP-------SPPCITT--------VSVNESLLTPLNLEI 100 AG G GY R+ G G P C++ V+VN+SLL PLN+E+ Sbjct: 70 AGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVEL 129 Query: 101 DPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEP 158 DP Q V+ +E+EQIK LN +FA+FIDKVRFLEQQN++LETK + Q + C+ NLEP Sbjct: 130 DPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEP 189 Query: 159 LFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKK 218 + GYI LR++ E + D RL SEL +++++E YKK+YE E+ R TAENEFV LKK Sbjct: 190 ILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKK 249 Query: 219 DVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDC 278 D D AY K +L+A V++L +EI FL+ LY+ EI +Q+H S+TSV++ +DN+RDL++D Sbjct: 250 DADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDS 309 Query: 279 IVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLT 338 I+AE++ Y++IA +S+AEAE+ Y++K +E++ RHG+ L+ T+ E+ ELNR+IQR+ Sbjct: 310 IIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIR 369 Query: 339 AEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVM 398 E+ N K Q + LE A+A +EQ+G+ AL DA+ KL ELEGAL +AK+++A ++REYQE+M Sbjct: 370 CEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELM 429 Query: 399 NSKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSS---------SRGGVVCGDLCVS 448 + KL LD+EIATYR+LLEGEE R+ E +V++ V S S GV G V+ Sbjct: 430 SLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLGASAVA 489 Query: 449 GSRPVTGS 456 GS T S Sbjct: 490 GSSGSTQS 497 >gi|47132620 keratin 2 [Homo sapiens] Length = 639 Score = 377 bits (967), Expect = e-104 Identities = 219/455 (48%), Positives = 305/455 (67%), Gaps = 15/455 (3%) Query: 48 GGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPS-------PPCITTVSVNESLLTPLNLEI 100 GGFG GG R G G G GG+ GP P I VSVN+SLL PLN+++ Sbjct: 111 GGFGGGGFGGG-RFGGFGGPGGV--GGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKV 167 Query: 101 DPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ--NRECCQSNLEP 158 DP Q VK +E+EQIK+LN++FA+FIDKVRFLEQQN++L+TK + Q N NLEP Sbjct: 168 DPEIQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEP 227 Query: 159 LFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKK 218 +F GYI++L+R + + A+ SELN++Q+++E YKKKYE+E+ R AEN+FV LKK Sbjct: 228 IFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKK 287 Query: 219 DVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDC 278 DVD AY+ K +L++ V+ L QEI+FL+ LY+ EI + ++DT+V++ +DNSR+L++D Sbjct: 288 DVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDS 347 Query: 279 IVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLT 338 I+AE+KAQY++IA RS+ EAE+ Y SK EE++ TV RHG++L+ K EI+ELNR+IQRL Sbjct: 348 IIAEVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQ 407 Query: 339 AEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVM 398 E+ + K Q ++ A+A +EQ+GE AL DAR KL +LE ALQ+AK+D+A L+R+YQE+M Sbjct: 408 GEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELM 467 Query: 399 NSKLGLDIEIATYRRLLEGEEQRLCEGVEA-VNVCVSSSR-GGVVCGDLCVSGSRPVTGS 456 N KL LD+EIATYR+LLEGEE R+ + + V V V+SS V GS S Sbjct: 468 NVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSS 527 Query: 457 VCSAPCNGNLVVSTGLCKPCGQLNTTCGGGSCGQG 491 +G+ +G + G + GGGS G Sbjct: 528 SGGGYSSGSSSYGSG-GRQSGSRGGSGGGGSISGG 561 >gi|194018511 keratin 77 [Homo sapiens] Length = 578 Score = 350 bits (899), Expect = 1e-96 Identities = 197/452 (43%), Positives = 296/452 (65%), Gaps = 18/452 (3%) Query: 4 GFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGS-------HSVC 56 G+ G GF G+ S + G R + G C G GGFG + Sbjct: 48 GYGIHGRGF--GSRSLYNLGGSRSISINLMGRSTSGF-CQGGGVGGFGGGRGFGVGSTGA 104 Query: 57 GGFRAGSCGRS-FGYRSGGVCGPSPPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEE 111 GGF G G + FG + G+ G P C I V++N+SLL PL+LE+DP Q +K +E Sbjct: 105 GGFGGGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQE 164 Query: 112 KEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ--NRECCQSNLEPLFAGYIETLRR 169 +EQI LN++FA+FIDKVRFLEQQN++L+TK + Q N +NLEPL YI LRR Sbjct: 165 REQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRR 224 Query: 170 EAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSD 229 + + + A+ R +E+ +Q+V+E YK KYE+E+ R +EN+FV LKKDVD AY+ K D Sbjct: 225 QVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVD 284 Query: 230 LEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDD 289 LE+ V+ L E++FL+ L+ E+ +Q+HISDT+V++ +DN+R L++D I+ ++ QY+ Sbjct: 285 LESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYEL 344 Query: 290 IATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNS 349 IA RS+ EAE+ Y++K +E++ T RHG+ L+ +K EI ELNR +QRL AE+ N K Q Sbjct: 345 IAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIE 404 Query: 350 KLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIA 409 ++++ ++ +E++GE AL DA KL +LE ALQ++K+++A L+R+YQ ++ KL LD+EIA Sbjct: 405 QMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIA 464 Query: 410 TYRRLLEGEEQRLCEGVEA-VNVCVSSSRGGV 440 TYR+LLEGEE R+ +++ V++ V +S+ V Sbjct: 465 TYRQLLEGEESRMSGELQSHVSISVQNSQVSV 496 >gi|89357932 keratin 5b [Homo sapiens] Length = 520 Score = 345 bits (885), Expect = 5e-95 Identities = 212/495 (42%), Positives = 300/495 (60%), Gaps = 21/495 (4%) Query: 17 FSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGR---SFGYRSG 73 FS SAC R RG R L G G GS GR FG SG Sbjct: 12 FSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEWSG 71 Query: 74 G----VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKV 129 G +C P I V++N++LLTPL +EIDP Q V+ +E ++I++LN++FA+FIDKV Sbjct: 72 GPGLSLCPPGG--IQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKV 129 Query: 130 RFLEQQNKLLETKLQFYQNRECC--QSNLEPLFAGYIETLRREAECVEADSGRLASELNH 187 RFLEQQNK+LETK Q + Q LEP+F ++ LR++ E ++ + G L +EL Sbjct: 130 RFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKA 189 Query: 188 VQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRL 247 ++ E YK KYEEE RAT EN+FV LKKDVD +L K +LE +EAL + + FL+ L Sbjct: 190 CRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHL 249 Query: 248 YEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCE 307 EEE+ LQ+ SDTSVV+ +DN+R L+ I+ E++A+Y++IA S+AEAE+ Y++K + Sbjct: 250 NEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQ 309 Query: 308 EMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALS 367 E++ + HG+ ++ TK +I++L++ IQRL ++ EN K QN+ L+AA+ +EQ+GE AL Sbjct: 310 ELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALK 369 Query: 368 DARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVE 427 DA+ K+ ELE AL+ AKQ++A L+ EYQE+ ++KL LD+EIATYRRLLEGEE R+ G Sbjct: 370 DAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRM-SGEC 428 Query: 428 AVNVCVSSSRGGVV--------CGDLCVSGS-RPVTGSVCSAPCNGNLVVSTGLCKPCGQ 478 V +SS G V G C GS + GS C++ G + G K Sbjct: 429 TSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDPVL 488 Query: 479 LNTTCGGGSCGQGRH 493 + + G S G H Sbjct: 489 DSCSVSGSSAGSSCH 503 >gi|226246665 keratin 72 isoform 2 [Homo sapiens] Length = 469 Score = 331 bits (849), Expect = 8e-91 Identities = 183/386 (47%), Positives = 255/386 (66%), Gaps = 48/386 (12%) Query: 57 GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 113 GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+ +E+E Sbjct: 68 GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127 Query: 114 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFAGYIETLRREA 171 QIK+LN++FA+FIDKVRFLEQQN++LETK Q + C+ NLEP++ GYI L+++ Sbjct: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187 Query: 172 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLE 231 E + D RL SEL ++Q+++E YKK+YE E+ R AENEFV LKKDVD AY+ K +L+ Sbjct: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247 Query: 232 ANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIA 291 A V++L EI F + LYE EI +QSHISDTS+V+ +DN+RDL++D I+AE++AQY++IA Sbjct: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307 Query: 292 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 351 +S+AEAE+ Y++KC + L Sbjct: 308 LKSKAEAETLYQTKCAD------------------------------------------L 325 Query: 352 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 411 E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY Sbjct: 326 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 385 Query: 412 RRLLEGEEQRLC-EGVEAVNVCVSSS 436 R+LLE EE R+ E +V++ V SS Sbjct: 386 RKLLESEECRMSGEYPNSVSISVISS 411 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.133 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,672,374 Number of Sequences: 37866 Number of extensions: 863823 Number of successful extensions: 5771 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 161 Number of HSP's successfully gapped in prelim test: 455 Number of HSP's that attempted gapping in prelim test: 4103 Number of HSP's gapped (non-prelim): 1537 length of query: 493 length of database: 18,247,518 effective HSP length: 106 effective length of query: 387 effective length of database: 14,233,722 effective search space: 5508450414 effective search space used: 5508450414 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.