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Search of human proteins with 169790841
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169790841 keratin 83 [Homo sapiens]
(493 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169790841 keratin 83 [Homo sapiens] 997 0.0
gi|169790853 keratin, hair, basic, 1 [Homo sapiens] 939 0.0
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap... 872 0.0
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap... 872 0.0
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap... 872 0.0
gi|14318422 keratin 86 [Homo sapiens] 872 0.0
gi|4504935 keratin 85 [Homo sapiens] 783 0.0
gi|15431316 keratin, hair, basic, 4 [Homo sapiens] 540 e-153
gi|27477127 keratin 82 [Homo sapiens] 522 e-148
gi|119395754 keratin 5 [Homo sapiens] 428 e-120
gi|5031839 keratin 6A [Homo sapiens] 422 e-118
gi|153791158 keratin 75 [Homo sapiens] 420 e-117
gi|119703753 keratin 6B [Homo sapiens] 420 e-117
gi|155969697 keratin 6C [Homo sapiens] 420 e-117
gi|4504919 keratin 8 [Homo sapiens] 411 e-115
gi|109148552 keratin 3 [Homo sapiens] 405 e-113
gi|67782365 keratin 7 [Homo sapiens] 402 e-112
gi|109255249 keratin 4 [Homo sapiens] 401 e-112
gi|28173564 keratin 73 [Homo sapiens] 400 e-111
gi|15618995 keratin 71 [Homo sapiens] 399 e-111
gi|153791670 keratin 76 [Homo sapiens] 394 e-109
gi|119395750 keratin 1 [Homo sapiens] 392 e-109
gi|28372503 keratin 72 isoform 1 [Homo sapiens] 387 e-108
gi|226246663 keratin 72 isoform 1 [Homo sapiens] 387 e-108
gi|32567786 keratin 6L [Homo sapiens] 385 e-107
gi|148612803 keratin 6 irs4 [Homo sapiens] 381 e-106
gi|47132620 keratin 2 [Homo sapiens] 377 e-104
gi|194018511 keratin 77 [Homo sapiens] 350 1e-96
gi|89357932 keratin 5b [Homo sapiens] 345 5e-95
gi|226246665 keratin 72 isoform 2 [Homo sapiens] 331 8e-91
>gi|169790841 keratin 83 [Homo sapiens]
Length = 493
Score = 997 bits (2578), Expect = 0.0
Identities = 493/493 (100%), Positives = 493/493 (100%)
Query: 1 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60
MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR
Sbjct: 1 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60
Query: 61 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120
AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS
Sbjct: 61 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120
Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180
RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR
Sbjct: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180
Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240
LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE
Sbjct: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240
Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300
IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES
Sbjct: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300
Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360
WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ
Sbjct: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360
Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420
QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ
Sbjct: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420
Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCGQLN 480
RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCGQLN
Sbjct: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCGQLN 480
Query: 481 TTCGGGSCGQGRH 493
TTCGGGSCGQGRH
Sbjct: 481 TTCGGGSCGQGRH 493
>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
Length = 505
Score = 939 bits (2428), Expect = 0.0
Identities = 468/491 (95%), Positives = 473/491 (96%), Gaps = 5/491 (1%)
Query: 1 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60
MTCG GF FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR
Sbjct: 1 MTCG-----SGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55
Query: 61 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120
AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS
Sbjct: 56 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115
Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180
RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR
Sbjct: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175
Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240
LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE
Sbjct: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235
Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300
IDFLRRLYEEEI ILQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES
Sbjct: 236 IDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295
Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360
WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ
Sbjct: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355
Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420
QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ
Sbjct: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415
Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCGQLN 480
RLCEG+ AVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGN+ VSTGLC PCGQLN
Sbjct: 416 RLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLN 475
Query: 481 TTCGGGSCGQG 491
TTCGGGSCG G
Sbjct: 476 TTCGGGSCGVG 486
>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 486
Score = 872 bits (2253), Expect = 0.0
Identities = 445/490 (90%), Positives = 456/490 (93%), Gaps = 9/490 (1%)
Query: 1 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60
MTCG CG R FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR
Sbjct: 1 MTCGSY---CGGRA--FSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55
Query: 61 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120
AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS
Sbjct: 56 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115
Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180
RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR
Sbjct: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175
Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240
LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE
Sbjct: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235
Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300
IDFLRRLYEEEIR+LQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES
Sbjct: 236 IDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295
Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360
WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ
Sbjct: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355
Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420
QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ
Sbjct: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415
Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNLVV-STGLCKPCGQ 478
RLCEGV +VNVCVSSSRGGVVCGDLC S + PV + V S P N N+VV +T C P +
Sbjct: 416 RLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR 475
Query: 479 LNTTCGGGSC 488
+ GGSC
Sbjct: 476 VGVC--GGSC 483
>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 486
Score = 872 bits (2253), Expect = 0.0
Identities = 445/490 (90%), Positives = 456/490 (93%), Gaps = 9/490 (1%)
Query: 1 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60
MTCG CG R FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR
Sbjct: 1 MTCGSY---CGGRA--FSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55
Query: 61 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120
AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS
Sbjct: 56 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115
Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180
RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR
Sbjct: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175
Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240
LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE
Sbjct: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235
Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300
IDFLRRLYEEEIR+LQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES
Sbjct: 236 IDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295
Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360
WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ
Sbjct: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355
Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420
QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ
Sbjct: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415
Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNLVV-STGLCKPCGQ 478
RLCEGV +VNVCVSSSRGGVVCGDLC S + PV + V S P N N+VV +T C P +
Sbjct: 416 RLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR 475
Query: 479 LNTTCGGGSC 488
+ GGSC
Sbjct: 476 VGVC--GGSC 483
>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
sapiens]
Length = 486
Score = 872 bits (2253), Expect = 0.0
Identities = 445/490 (90%), Positives = 456/490 (93%), Gaps = 9/490 (1%)
Query: 1 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60
MTCG CG R FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR
Sbjct: 1 MTCGSY---CGGRA--FSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55
Query: 61 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120
AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS
Sbjct: 56 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115
Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180
RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR
Sbjct: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175
Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240
LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE
Sbjct: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235
Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300
IDFLRRLYEEEIR+LQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES
Sbjct: 236 IDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295
Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360
WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ
Sbjct: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355
Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420
QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ
Sbjct: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415
Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNLVV-STGLCKPCGQ 478
RLCEGV +VNVCVSSSRGGVVCGDLC S + PV + V S P N N+VV +T C P +
Sbjct: 416 RLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR 475
Query: 479 LNTTCGGGSC 488
+ GGSC
Sbjct: 476 VGVC--GGSC 483
>gi|14318422 keratin 86 [Homo sapiens]
Length = 486
Score = 872 bits (2253), Expect = 0.0
Identities = 445/490 (90%), Positives = 456/490 (93%), Gaps = 9/490 (1%)
Query: 1 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60
MTCG CG R FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR
Sbjct: 1 MTCGSY---CGGRA--FSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55
Query: 61 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120
AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS
Sbjct: 56 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115
Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180
RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR
Sbjct: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175
Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240
LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE
Sbjct: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235
Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300
IDFLRRLYEEEIR+LQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES
Sbjct: 236 IDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295
Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360
WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ
Sbjct: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355
Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420
QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ
Sbjct: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415
Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNLVV-STGLCKPCGQ 478
RLCEGV +VNVCVSSSRGGVVCGDLC S + PV + V S P N N+VV +T C P +
Sbjct: 416 RLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR 475
Query: 479 LNTTCGGGSC 488
+ GGSC
Sbjct: 476 VGVC--GGSC 483
>gi|4504935 keratin 85 [Homo sapiens]
Length = 507
Score = 783 bits (2023), Expect = 0.0
Identities = 408/500 (81%), Positives = 438/500 (87%), Gaps = 20/500 (4%)
Query: 7 SIGCGFRPGNFSCVSACGPRP-SRCCITAAPYRGISCYRGLTGGFGSHSVC--------- 56
S GCG NFS SA P+ +RCCI+AAPYRG+SCYRGLTG FGS S+C
Sbjct: 9 SSGCGVTR-NFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTG-FGSRSLCNLGSCGPRI 66
Query: 57 --GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ 114
GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ
Sbjct: 67 AVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ 126
Query: 115 IKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECV 174
IKSLNSRFAAFIDKVRFLEQQNKLLETK QFYQN+ CC+SNLEPLF+GYIETLRREAECV
Sbjct: 127 IKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETLRREAECV 186
Query: 175 EADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANV 234
EADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFV LKKDVDCAYLRKSDLEANV
Sbjct: 187 EADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANV 246
Query: 235 EALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRS 294
EAL++E FLRRLYEEEIR+LQ+HISDTSV+VK+DNSRDLNMDCI+AEIKAQYDD+A+RS
Sbjct: 247 EALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRS 306
Query: 295 RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAA 354
RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE+ENAKCQ +KLEAA
Sbjct: 307 RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAA 366
Query: 355 VAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRL 414
VA++EQQGEAALSDARCKLAELEGALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRL
Sbjct: 367 VAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRL 426
Query: 415 LEGEEQRLCEGVEAVNVCVSSSRGGVVCGDLCVSGS--RPVTGSVCSAPCNGNLVVSTGL 472
LEGEE RLCEGV +VNVCVSSSRGGV CG L S + R +T S SA VV+
Sbjct: 427 LEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTPGRQIT-SGPSAIGGSITVVAPDS 485
Query: 473 CKPCGQLNTTCGGGSCGQGR 492
C PC +++ SCG R
Sbjct: 486 CAPCQPRSSSF---SCGSSR 502
>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
Length = 600
Score = 540 bits (1391), Expect = e-153
Identities = 290/468 (61%), Positives = 360/468 (76%), Gaps = 11/468 (2%)
Query: 20 VSACGPRPSRCCIT--AAPYRGISCYRGLTGGFGSHSVCG-GFRAGSC------GRSFGY 70
++A G RP C + A G RG+ G + S G GF AGS G FGY
Sbjct: 65 IAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGY 124
Query: 71 RSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVR 130
R GGV P+ P IT V+VN+SLLTPLNLEIDPNAQ VK++EKEQIK+LN++FA+FIDKVR
Sbjct: 125 RVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVR 184
Query: 131 FLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQE 190
FLEQQNKLLETK F Q ++C +SNLEPLF YI LRR+ E + +D RL +E NH+Q+
Sbjct: 185 FLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQD 244
Query: 191 VLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 250
VLEG+KKKYEEEV RA AENEFVALKKDVD A++ KSDLEANV+ L QEIDFL+ LY E
Sbjct: 245 VLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYME 304
Query: 251 EIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMK 310
EI++LQSHIS+TSV+VK+DNSRDLN+D I+AE+KAQY+++A RSRA+AE+WY++K EEM+
Sbjct: 305 EIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQ 364
Query: 311 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 370
T +H + LR + EINEL R+IQRL AE+E+AK Q +KLEAAVA++EQQGEA LSDA+
Sbjct: 365 VTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAK 424
Query: 371 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVEAVN 430
CKLA+LE ALQ+AKQDMA + EYQE+MN+KLGLDIEIATYRRLLEGEE RLCEGV VN
Sbjct: 425 CKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVN 484
Query: 431 VCVSSSRGGVVCG-DLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCG 477
+ VSSSRGG+VCG + V+GS G V + + ++ ++G+ CG
Sbjct: 485 ISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSG-SSSVCATSGVLASCG 531
>gi|27477127 keratin 82 [Homo sapiens]
Length = 513
Score = 522 bits (1345), Expect = e-148
Identities = 296/503 (58%), Positives = 356/503 (70%), Gaps = 34/503 (6%)
Query: 12 FRPGN------FSCVSACGPRP-SRCCITAAPYRGISCYRGLT--GGFGSHSVCG-GFR- 60
F+PG+ FS SA PR + ++ P R RGL G GS S+C GF
Sbjct: 6 FQPGSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRP-GGGRGLRALGCLGSRSLCNVGFGR 64
Query: 61 ---AGSCGRS---FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ 114
A CG + FGYR G CGPS CIT V++NESLL PL LEIDP Q VK++EKEQ
Sbjct: 65 PRVASRCGGTLPGFGYRLGATCGPSA-CITPVTINESLLVPLALEIDPTVQRVKRDEKEQ 123
Query: 115 IKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECV 174
IK LN+RFA+FI+KVRFLEQ+NKLLETK F Q + CCQ+N+EP+F GYI LRR+ +CV
Sbjct: 124 IKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCV 183
Query: 175 EADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANV 234
D RL SEL +Q LEGYKKKYEEE++LR ENEFVALKKDVD A+L K+DLE N
Sbjct: 184 SGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNA 243
Query: 235 EALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRS 294
EAL+QEIDFL+ LYEEEI +LQS IS+TSV+VK+DNSR+L++D I+AEIKAQYDDIA+RS
Sbjct: 244 EALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRS 303
Query: 295 RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAA 354
+AEAE+WY+ + EE++ T H + LR K EI E+N++IQRL E EN K Q KLE A
Sbjct: 304 KAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGA 363
Query: 355 VAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRL 414
+A++EQQGEAAL+DA+CKLA LE ALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRL
Sbjct: 364 IAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRL 423
Query: 415 LEGEEQRLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSV-----CSAPCNGNLVVS 469
LEGEE RLCEG+ VN+ VSSS+G + VS TG + CS G L V
Sbjct: 424 LEGEEHRLCEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGELYVP 483
Query: 470 TGLCKPCGQLNTTCGGGSCGQGR 492
C+P G L SCG GR
Sbjct: 484 ---CEPQGLL-------SCGSGR 496
>gi|119395754 keratin 5 [Homo sapiens]
Length = 590
Score = 428 bits (1101), Expect = e-120
Identities = 229/401 (57%), Positives = 300/401 (74%), Gaps = 9/401 (2%)
Query: 45 GLTGGFGSHSVCGGFRAGSCGRSFGYR-SGGVCGPS-PPC----ITTVSVNESLLTPLNL 98
G GG GS GG G G G GG GP P C I V+VN+SLLTPLNL
Sbjct: 96 GFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 155
Query: 99 EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 156
+IDP+ Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK Q + + + NL
Sbjct: 156 QIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 215
Query: 157 EPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVAL 216
EPLF YI LRR+ + + + GRL SEL ++Q+++E +K KYE+E+ R TAENEFV L
Sbjct: 216 EPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVML 275
Query: 217 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNM 276
KKDVD AY+ K +LEA V+AL+ EI+F++ ++ E+ +Q+H+SDTSVV+ +DN+R+L++
Sbjct: 276 KKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDL 335
Query: 277 DCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 336
D I+AE+KAQY++IA RSR EAESWY++K EE++ T RHG+ LR TK EI+E+NRMIQR
Sbjct: 336 DSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQR 395
Query: 337 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 396
L AE++N K Q + L+ A+A +EQ+GE AL DAR KLAELE ALQKAKQDMA L+REYQE
Sbjct: 396 LRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQE 455
Query: 397 VMNSKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSSS 436
+MN+KL LD+EIATYR+LLEGEE RL EGV VN+ V +S
Sbjct: 456 LMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTS 496
>gi|5031839 keratin 6A [Homo sapiens]
Length = 564
Score = 422 bits (1085), Expect = e-118
Identities = 250/516 (48%), Positives = 331/516 (64%), Gaps = 33/516 (6%)
Query: 4 GFNSIGCGFRPGNFSCVSACGPRP--SRCCITAAPYRGISCYRG---LTGGFGSHSVCGG 58
GF+S+ G+ ACG SR + IS G ++GG+GS + G
Sbjct: 32 GFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAG-GS 90
Query: 59 FRAGSCGRSFGYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNL 98
+ G G FG+ +GG GP P C I V+VN+SLLTPLNL
Sbjct: 91 YGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 150
Query: 99 EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 156
+IDP Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK Q + + + NL
Sbjct: 151 QIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNL 210
Query: 157 EPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVAL 216
EPLF YI LRR+ + + + GRL SEL +Q+++E +K KYE+E+ R AENEFV L
Sbjct: 211 EPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTL 270
Query: 217 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNM 276
KKDVD AY+ K +L+A + L EI+FLR LY+ E+ +Q+HISDTSVV+ +DN+R+L++
Sbjct: 271 KKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDL 330
Query: 277 DCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 336
D I+AE+KAQY++IA RSRAEAESWY++K EE++ T RHG+ LR TK+EI E+NRMIQR
Sbjct: 331 DSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQR 390
Query: 337 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 396
L +E+++ K Q + L+AA+A +EQ+GE AL DA+ KL LE ALQKAKQD+A L++EYQE
Sbjct: 391 LRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQE 450
Query: 397 VMNSKLGLDIEIATYRRLLEGEEQRL-CEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTG 455
+MN KL LD+EIATYR+LLEGEE RL EGV VN+ V S G GS G
Sbjct: 451 LMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLG 510
Query: 456 SVCSAPCNGNLVVSTGLCKPCGQL----NTTCGGGS 487
S L V G G+ ++ GGGS
Sbjct: 511 GGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGS 546
>gi|153791158 keratin 75 [Homo sapiens]
Length = 551
Score = 420 bits (1080), Expect = e-117
Identities = 244/462 (52%), Positives = 315/462 (68%), Gaps = 32/462 (6%)
Query: 39 GISCYRGLTGGFGSH-SVCGGFRAGSCGRSFGYRSGGVCGPS-PPC----ITTVSVNESL 92
G SC G G + V GF G G GG GPS P C I V+VN+SL
Sbjct: 77 GSSCRSGFGGRASNRFGVNSGFGYG------GGVGGGFSGPSFPVCPPGGIQEVTVNQSL 130
Query: 93 LTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--E 150
LTPL+L+IDP Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK Q +
Sbjct: 131 LTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSR 190
Query: 151 CCQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAE 210
+ NLEPLF Y LRR+ E + + GRL +EL ++Q+V+E +K +YE+E+ R AE
Sbjct: 191 TVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAE 250
Query: 211 NEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDN 270
NEFVALKKDVD AY+ K +LEA V++L +EI+F+ +++ E+ LQ+ + DTSVV+ +DN
Sbjct: 251 NEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDN 310
Query: 271 SRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINEL 330
+R+L++D I+AE+KAQY+DIA RSRAEAESWY++K EE++ T RHG+ LR TK+EI+E+
Sbjct: 311 NRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEM 370
Query: 331 NRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACL 390
NRMIQRL AE+++ K Q S L+ A+A +EQ+GE AL DAR KL +LE ALQKAKQDMA L
Sbjct: 371 NRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARL 430
Query: 391 IREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSSSRGGVVCGDLCVSG 449
+REYQE+MN KL LD+EIATYR+LLEGEE RL EGV VN+ V +S G SG
Sbjct: 431 LREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYG----SG 486
Query: 450 SRPVTGSVCSAPCNGNLVVSTGLCKPCGQLNTTCGGGSCGQG 491
S+ GNL GL G TT GG S G G
Sbjct: 487 ---------SSIGGGNL----GLGGGSGYSFTTSGGHSLGAG 515
>gi|119703753 keratin 6B [Homo sapiens]
Length = 564
Score = 420 bits (1080), Expect = e-117
Identities = 250/516 (48%), Positives = 331/516 (64%), Gaps = 33/516 (6%)
Query: 4 GFNSIGCGFRPGNFSCVSACGPRP--SRCCITAAPYRGISCYRG---LTGGFGSHSVCGG 58
GF+SI G+ ACG SR + IS G ++GG+GS + G
Sbjct: 32 GFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAG-GS 90
Query: 59 FRAGSCGRSFGYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNL 98
+ G G FG+ +GG GP P C I V+VN+SLLTPLNL
Sbjct: 91 YGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 150
Query: 99 EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 156
+IDP Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK Q + + + NL
Sbjct: 151 QIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 210
Query: 157 EPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVAL 216
EPLF YI LRR+ + + + GRL SEL ++Q+++E K KYE+E+ R AENEFV L
Sbjct: 211 EPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTL 270
Query: 217 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNM 276
KKDVD AY+ K +L+A + L EI+FLR LY+ E+ +Q+HISDTSVV+ +DN+R+L++
Sbjct: 271 KKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDL 330
Query: 277 DCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 336
D I+AE+KAQY++IA RSRAEAESWY++K EE++ T RHG+ LR TK+EI E+NRMIQR
Sbjct: 331 DSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEIAEINRMIQR 390
Query: 337 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 396
L +E+++ K Q + L+AA+A +EQ+GE AL DA+ KL LE ALQKAKQD+A L++EYQE
Sbjct: 391 LRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQE 450
Query: 397 VMNSKLGLDIEIATYRRLLEGEEQRL-CEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTG 455
+MN KL LD+EIATYR+LLEGEE RL EGV VN+ V S G GS G
Sbjct: 451 LMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLG 510
Query: 456 SVCSAPCNGNLVVSTGLCKPCGQLN----TTCGGGS 487
S L V G G+ ++ GGGS
Sbjct: 511 GGSSYSYGSGLGVGGGFSSSSGRATGGGLSSVGGGS 546
>gi|155969697 keratin 6C [Homo sapiens]
Length = 564
Score = 420 bits (1079), Expect = e-117
Identities = 250/516 (48%), Positives = 331/516 (64%), Gaps = 33/516 (6%)
Query: 4 GFNSIGCGFRPGNFSCVSACGPRP--SRCCITAAPYRGISCYRG---LTGGFGSHSVCGG 58
GF+SI G+ ACG SR + IS G ++GG+GS + G
Sbjct: 32 GFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAG-GS 90
Query: 59 FRAGSCGRSFGYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNL 98
+ G G FG+ +GG GP P C I V+VN+SLLTPLNL
Sbjct: 91 YGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 150
Query: 99 EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 156
+IDP Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK Q + + + NL
Sbjct: 151 QIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 210
Query: 157 EPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVAL 216
EPLF YI LRR+ + + + GRL SEL ++Q+++E K KYE+E+ R AENEFV L
Sbjct: 211 EPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTL 270
Query: 217 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNM 276
KKDVD AY+ K +L+A + L EI+FLR LY+ E+ +Q+HISDTSVV+ +DN+R+L++
Sbjct: 271 KKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDL 330
Query: 277 DCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 336
D I+AE+KAQY++IA RSRAEAESWY++K EE++ T RHG+ LR TK+EI E+NRMIQR
Sbjct: 331 DSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQR 390
Query: 337 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 396
L +E+++ K Q + L+AA+A +EQ+GE AL DA+ KL LE ALQKAKQD+A L++EYQE
Sbjct: 391 LRSEIDHVKKQCASLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQE 450
Query: 397 VMNSKLGLDIEIATYRRLLEGEEQRL-CEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTG 455
+MN KL LD+EIATYR+LLEGEE RL EGV VNV V S G GS G
Sbjct: 451 LMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNVSVVQSTISSGYGGASGVGSGLGLG 510
Query: 456 SVCSAPCNGNLVVSTGLCKPCGQL----NTTCGGGS 487
S L + G G+ ++ GGGS
Sbjct: 511 GGSSYSYGSGLGIGGGFSSSSGRAIGGGLSSVGGGS 546
>gi|4504919 keratin 8 [Homo sapiens]
Length = 483
Score = 411 bits (1056), Expect = e-115
Identities = 218/396 (55%), Positives = 286/396 (72%), Gaps = 1/396 (0%)
Query: 44 RGLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPC-ITTVSVNESLLTPLNLEIDP 102
R T G GS F G GG G S IT V+VN+SLL+PL LE+DP
Sbjct: 23 RSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGGITAVTVNQSLLSPLVLEVDP 82
Query: 103 NAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAG 162
N Q V+ +EKEQIK+LN++FA+FIDKVRFLEQQNK+LETK Q ++ +SN++ +F
Sbjct: 83 NIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKTARSNMDNMFES 142
Query: 163 YIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDC 222
YI LRR+ E + + +L +EL ++Q ++E +K KYE+E+ R ENEFV +KKDVD
Sbjct: 143 YINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDE 202
Query: 223 AYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAE 282
AY+ K +LE+ +E L EI+FLR+LYEEEIR LQS ISDTSVV+ +DNSR L+MD I+AE
Sbjct: 203 AYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAE 262
Query: 283 IKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVE 342
+KAQY+DIA RSRAEAES Y+ K EE+++ +HG+ LRRTK EI+E+NR I RL AE+E
Sbjct: 263 VKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIE 322
Query: 343 NAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKL 402
K Q + LEAA+A +EQ+GE A+ DA KL+ELE ALQ+AKQDMA +REYQE+MN KL
Sbjct: 323 GLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLREYQELMNVKL 382
Query: 403 GLDIEIATYRRLLEGEEQRLCEGVEAVNVCVSSSRG 438
LDIEIATYR+LLEGEE RL G++ +++ ++ G
Sbjct: 383 ALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSG 418
>gi|109148552 keratin 3 [Homo sapiens]
Length = 628
Score = 405 bits (1041), Expect = e-113
Identities = 219/397 (55%), Positives = 286/397 (72%), Gaps = 11/397 (2%)
Query: 45 GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNA 104
G GGFG GG GS G G+ GG P I V++N+SLL PLN+EIDP
Sbjct: 138 GGPGGFGGSGGFGG--PGSLGSPGGFGPGGF----PGGIQEVTINQSLLQPLNVEIDPQI 191
Query: 105 QCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ----SNLEPLF 160
VK +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK Q + +NLEPLF
Sbjct: 192 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLF 251
Query: 161 AGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDV 220
+I LR + + + GRL SEL ++++++E +KKKYE+E+ R AENEFV LKKDV
Sbjct: 252 ENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDV 311
Query: 221 DCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIV 280
D AY+ K +L+A V+ALI EIDFLR LY+ E+ +QSHISDTSVV+ +DN+R L++D I+
Sbjct: 312 DSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSII 371
Query: 281 AEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE 340
AE++AQY+DIA RS+AEAE+ Y++K E++ T RHG+ LR TK EI ELNRMIQRL AE
Sbjct: 372 AEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAE 431
Query: 341 VENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNS 400
+E K QN+ L+ A+A++EQ GE AL DA KL EL+ ALQ+AK D+A L+R+YQE+MN
Sbjct: 432 IEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNV 491
Query: 401 KLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSSS 436
KL LD+EIATYR+LLEGEE R+ E AV++ V SS
Sbjct: 492 KLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSS 528
>gi|67782365 keratin 7 [Homo sapiens]
Length = 469
Score = 402 bits (1032), Expect = e-112
Identities = 220/398 (55%), Positives = 287/398 (72%), Gaps = 6/398 (1%)
Query: 48 GGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 107
GG GS S+ G G+ RS GP I V++N+SLL PL L+ DP+ Q V
Sbjct: 32 GGLGSSSLYG---LGASRPRVAVRSA-YGGPVGAGIREVTINQSLLAPLRLDADPSLQRV 87
Query: 108 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEP-LFAGYIET 166
+QEE EQIK+LN++FA+FIDKVRFLEQQNKLLETK Q ++ +S+ P +F I
Sbjct: 88 RQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRLPDIFEAQIAG 147
Query: 167 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLR 226
LR + E ++ D GRL +EL +Q+V+E +K KYE+E+ R AENEFV LKKDVD AY+
Sbjct: 148 LRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMS 207
Query: 227 KSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQ 286
K +LEA V+AL EI+FLR L E E+ LQS ISDTSVV+ +DNSR L++D I+AE+KAQ
Sbjct: 208 KVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQ 267
Query: 287 YDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 346
Y+++A SRAEAE+WY++K E ++A +HG+ LR T+ EI+E+NR IQRL AE++N K
Sbjct: 268 YEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKN 327
Query: 347 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 406
Q +KLEAA+A++E++GE AL DAR K ELE ALQ+ KQDMA +REYQE+M+ KL LDI
Sbjct: 328 QRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDI 387
Query: 407 EIATYRRLLEGEEQRLC-EGVEAVNVCVSSSRGGVVCG 443
EIATYR+LLEGEE RL +GV AVN+ V +S GG G
Sbjct: 388 EIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSG 425
>gi|109255249 keratin 4 [Homo sapiens]
Length = 594
Score = 401 bits (1030), Expect = e-112
Identities = 227/463 (49%), Positives = 310/463 (66%), Gaps = 21/463 (4%)
Query: 2 TCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRG-----LTGGFGSHSVC 56
+CG +G G R G FS VS G RC R + RG ++ C
Sbjct: 90 SCGSAIVGGGKR-GAFSSVSMSGGA-GRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGAC 147
Query: 57 ----GGFRAGSCGRSFGYRSGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCV 107
GGF G G FG G GP P C I V++N+SLLTPL++EIDP Q V
Sbjct: 148 FGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDPEIQKV 207
Query: 108 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFAGYIE 165
+ EE+EQIK LN++FA+FIDKV+FLEQQNK+LETK Q + S NLEPLF Y+
Sbjct: 208 RTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFETYLS 267
Query: 166 TLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYL 225
LR++ + + D GRL SEL +Q+ +E +K KYEEE+ R AEN+FV LKKDVD AYL
Sbjct: 268 VLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYL 327
Query: 226 RKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKA 285
K +LEA V++L EI+FL+ LY+ E+ +Q+H+SDTSVV+ +DN+R+L++D I+AE++A
Sbjct: 328 NKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRA 387
Query: 286 QYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAK 345
QY++IA RS+AEAE+ Y++K ++++ +V +HG+ L+ TK EI ELNRMIQRL AE+EN K
Sbjct: 388 QYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIK 447
Query: 346 CQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLD 405
Q L+ +VA +EQ+GE AL DA K ELE ALQ+AK+++A ++REYQE+M+ KL LD
Sbjct: 448 KQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVKLALD 507
Query: 406 IEIATYRRLLEGEEQRL---CEGVEAVNVCVSSSRGGVVCGDL 445
IEIATYR+LLEGEE R+ C+ +++V S+ G + G L
Sbjct: 508 IEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGL 550
>gi|28173564 keratin 73 [Homo sapiens]
Length = 540
Score = 400 bits (1027), Expect = e-111
Identities = 223/459 (48%), Positives = 308/459 (67%), Gaps = 21/459 (4%)
Query: 45 GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEID 101
G GG+G G +G G FG + G PS P I V++N+SLL PLN+E+D
Sbjct: 66 GWAGGYGFGR---GRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELD 122
Query: 102 PNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPL 159
P Q V+ +E+EQIK LN++FA+FIDKVRFLEQQN++LETK + Q + C++NLEP+
Sbjct: 123 PEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPI 182
Query: 160 FAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKD 219
GYI LR++ E + D RL SEL V+EV+E YKK+YEEE+ R TAENEFV LKKD
Sbjct: 183 LEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKD 242
Query: 220 VDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCI 279
VD AY K +L+A V+AL EI F + LYE E +QSHISDTS+++ +DN+R+L++D I
Sbjct: 243 VDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSI 302
Query: 280 VAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTA 339
+AE++AQY++IA +S+AEAE+ Y++K +E++ RHG+ L+ TK EI+EL R+IQRL +
Sbjct: 303 IAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRS 362
Query: 340 EVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMN 399
E+E+ K Q + LE A+A +EQ+G+ AL DAR KL ELEGALQ+AK+++A ++REYQE+++
Sbjct: 363 EIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLS 422
Query: 400 SKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSSSRGGVVCGDLCVSG--------- 449
KL LDIEIATYR+LLEGEE R+ E +V++ V +S + G G
Sbjct: 423 VKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTYGY 482
Query: 450 -SRPVTGSVCSAPCNGNLVVSTGLCKPCGQLNTTCGGGS 487
V+G P G V +G C P G+ T G S
Sbjct: 483 WPSSVSGGYSMLP--GGCVTGSGNCSPRGEARTRLGSAS 519
>gi|15618995 keratin 71 [Homo sapiens]
Length = 523
Score = 399 bits (1024), Expect = e-111
Identities = 224/447 (50%), Positives = 307/447 (68%), Gaps = 32/447 (7%)
Query: 44 RGLTGGFGSHSV--CGGFR----AGSCGRSFGY-----RSGGVCGP-------SPPCITT 85
+GL+GGFGS S+ GG R A G+S GY R+ G G P C T
Sbjct: 37 KGLSGGFGSRSLYSLGGVRSLNVASGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTV 96
Query: 86 --------VSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNK 137
V+VNESLL PLN+E+DP Q V+ +E+EQIK+LN++FA+FIDKVRFLEQQN+
Sbjct: 97 CPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQ 156
Query: 138 LLETKLQFYQNREC--CQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGY 195
+LETK + Q + C++NLEP+ GYI LR++ E + D RL SEL +V++V+E Y
Sbjct: 157 VLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDY 216
Query: 196 KKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRIL 255
KK+YEEE+ R AENEFV LKKDVD AY K +L+A VE++ QEI F R L+E EI +
Sbjct: 217 KKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQI 276
Query: 256 QSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIR 315
QSHISD SV++ +DN+R+L++D I+ E++ QY++IA +S+AEAE+ Y++K +E++ R
Sbjct: 277 QSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGR 336
Query: 316 HGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAE 375
HG+ L+ TK EI+EL R+IQR+ +E+EN K Q S LE A+A +EQ+G+ AL DAR KL E
Sbjct: 337 HGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDE 396
Query: 376 LEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNV-CV 433
LEGAL +AK+++A ++REYQE+M+ KL LD+EIATYR+LLE EE R+ E V++ +
Sbjct: 397 LEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISII 456
Query: 434 SSSRGGVVCG--DLCVSGSRPVTGSVC 458
SS+ GG V G VSG S C
Sbjct: 457 SSTSGGSVYGFRPSMVSGGYVANSSNC 483
>gi|153791670 keratin 76 [Homo sapiens]
Length = 638
Score = 394 bits (1012), Expect = e-109
Identities = 228/464 (49%), Positives = 306/464 (65%), Gaps = 25/464 (5%)
Query: 45 GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNA 104
G GGFG V GG GS G G+ GG P I V VN+SLL PLN+EIDP
Sbjct: 123 GGAGGFGGPGVFGG--PGSFGGPGGFGPGGF----PGGIQEVIVNQSLLQPLNVEIDPQI 176
Query: 105 QCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ--SNLEPLFAG 162
VK +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK + Q + S+LEP F
Sbjct: 177 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFES 236
Query: 163 YIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDC 222
YI L ++ + + + G L EL +Q+++E +KKKYE+E+ R AENEFV LKKDVD
Sbjct: 237 YISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDA 296
Query: 223 AYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAE 282
A++ K +L+A V++L E+ FLR LYE E+ +QSH SDTSVV+ +DN+R L++ I+AE
Sbjct: 297 AFMNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAE 356
Query: 283 IKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVE 342
++AQY++IA RS++EAE+ Y++K E++ T RHG+ LR TK EI ELNRMIQRL AE+E
Sbjct: 357 VRAQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIE 416
Query: 343 NAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKL 402
N K QN+ L+ A+A++EQ+GE AL DA KL +L+ ALQKAK D+A L+R+YQE+MN KL
Sbjct: 417 NVKKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKL 476
Query: 403 GLDIEIATYRRLLEGEEQRLCEGVEAVNVCVS-------------SSRGGVVCGDLCVSG 449
LD+EIATYR+LLEGEE R+ ++ VC+S SSRG V G + SG
Sbjct: 477 ALDVEIATYRKLLEGEECRMSGECQSA-VCISVVSNVTSTSGSSGSSRG--VFGGVSGSG 533
Query: 450 SRPVTGSVCSAPCNGNLVVSTGLCKPCGQLNTTCGGGSCGQGRH 493
S G S+ +G VS G G +++ GG G +
Sbjct: 534 SGGYKGGSSSSSSSG-YGVSGGSGSGYGGVSSGSTGGRGSSGSY 576
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 392 bits (1008), Expect = e-109
Identities = 223/448 (49%), Positives = 308/448 (68%), Gaps = 9/448 (2%)
Query: 48 GGFGSHSVCGGFRAGSCGRS-FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQC 106
GGFGS GGF G G +G G VC P I V++N+SLL PLN+EIDP Q
Sbjct: 120 GGFGSGG--GGFGGGGFGGGGYGGGYGPVCPPGG--IQEVTINQSLLQPLNVEIDPEIQK 175
Query: 107 VKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFAGYI 164
VK E+EQIKSLN++FA+FIDKVRFLEQQN++L+TK + Q + NLEP F +I
Sbjct: 176 VKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFI 235
Query: 165 ETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAY 224
LRR + +++D RL SEL ++Q+++E Y+ KYE+E+ R AENEFV +KKDVD AY
Sbjct: 236 NNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAY 295
Query: 225 LRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIK 284
+ K DL+A ++ L QEIDFL LY+ E+ +Q+ IS+T+V++ +DN+R L++D I+AE+K
Sbjct: 296 MTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVK 355
Query: 285 AQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENA 344
AQY+DIA +S+AEAES Y+SK EE++ T RHG+++R +K EI+ELNR+IQRL +E++N
Sbjct: 356 AQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNV 415
Query: 345 KCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGL 404
K Q S L+ +++ +EQ+GE AL DA+ KL +LE ALQ+AK+D+A L+R+YQE+MN+KL L
Sbjct: 416 KKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLAL 475
Query: 405 DIEIATYRRLLEGEEQRLCEGVEAVNVCVS-SSRGGVVCGDLCVSGSRPVTGSVCSAPCN 463
D+EIATYR LLEGEE R+ G A NV VS S+ + G G GS S+ +
Sbjct: 476 DLEIATYRTLLEGEESRM-SGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGS 534
Query: 464 GNLVVSTGLCKPCGQLNTTCGGGSCGQG 491
G +G G+ + GG S G G
Sbjct: 535 GGGSYGSGGGGGGGRGSYGSGGSSYGSG 562
>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 387 bits (995), Expect = e-108
Identities = 202/386 (52%), Positives = 285/386 (73%), Gaps = 6/386 (1%)
Query: 57 GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 113
GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+ +E+E
Sbjct: 68 GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127
Query: 114 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFAGYIETLRREA 171
QIK+LN++FA+FIDKVRFLEQQN++LETK Q + C+ NLEP++ GYI L+++
Sbjct: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187
Query: 172 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLE 231
E + D RL SEL ++Q+++E YKK+YE E+ R AENEFV LKKDVD AY+ K +L+
Sbjct: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247
Query: 232 ANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIA 291
A V++L EI F + LYE EI +QSHISDTS+V+ +DN+RDL++D I+AE++AQY++IA
Sbjct: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307
Query: 292 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 351
+S+AEAE+ Y++K +E++ T +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + L
Sbjct: 308 LKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADL 367
Query: 352 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 411
E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 368 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 427
Query: 412 RRLLEGEEQRLC-EGVEAVNVCVSSS 436
R+LLE EE R+ E +V++ V SS
Sbjct: 428 RKLLESEECRMSGEYPNSVSISVISS 453
>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 387 bits (995), Expect = e-108
Identities = 202/386 (52%), Positives = 285/386 (73%), Gaps = 6/386 (1%)
Query: 57 GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 113
GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+ +E+E
Sbjct: 68 GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127
Query: 114 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFAGYIETLRREA 171
QIK+LN++FA+FIDKVRFLEQQN++LETK Q + C+ NLEP++ GYI L+++
Sbjct: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187
Query: 172 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLE 231
E + D RL SEL ++Q+++E YKK+YE E+ R AENEFV LKKDVD AY+ K +L+
Sbjct: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247
Query: 232 ANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIA 291
A V++L EI F + LYE EI +QSHISDTS+V+ +DN+RDL++D I+AE++AQY++IA
Sbjct: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307
Query: 292 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 351
+S+AEAE+ Y++K +E++ T +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + L
Sbjct: 308 LKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADL 367
Query: 352 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 411
E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 368 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 427
Query: 412 RRLLEGEEQRLC-EGVEAVNVCVSSS 436
R+LLE EE R+ E +V++ V SS
Sbjct: 428 RKLLESEECRMSGEYPNSVSISVISS 453
>gi|32567786 keratin 6L [Homo sapiens]
Length = 535
Score = 385 bits (988), Expect = e-107
Identities = 215/434 (49%), Positives = 294/434 (67%), Gaps = 31/434 (7%)
Query: 39 GISCYRGLTGGFGSHS-------------VCGGFRAGSCGRSFGYRSGGVCGPS------ 79
G C G TGGFGS S V GG G FG+ S G
Sbjct: 47 GAHCGPG-TGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTF 105
Query: 80 -PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQ 134
P C I V+VN+SLLTPL++EIDP Q V+ +E+EQIK+LN++FA+FIDKVRFLEQ
Sbjct: 106 GPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQ 165
Query: 135 QNKLLETKLQFYQ----NRECCQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQE 190
QNK+LETK Q N ++NLEPLF Y+ ++R + ++++ GRL SEL +VQ+
Sbjct: 166 QNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQD 225
Query: 191 VLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 250
++E +K KYE+E+ AENEFV LKKDVD AY+ + DL V L QEIDFL++LYE
Sbjct: 226 LVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEM 285
Query: 251 EIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMK 310
E+ +Q+H+S+T+VV+ +DN+R+L++D I+AE+KAQY+ IA RSRAEAE+WY++K EE++
Sbjct: 286 ELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQ 345
Query: 311 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 370
T +HG+ LR TK EI EL R IQRL E + AK Q +L+ A+A++EQ+GE AL DA+
Sbjct: 346 VTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQ 405
Query: 371 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVEAV 429
KL +L+ AL +AK+D+ L+R+YQE+MN KL LD+EIATYR+LLE EE R+ E AV
Sbjct: 406 KKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAV 465
Query: 430 NVCVSSSRGGVVCG 443
++ V+ + VCG
Sbjct: 466 SISVTGN-STTVCG 478
>gi|148612803 keratin 6 irs4 [Homo sapiens]
Length = 529
Score = 381 bits (979), Expect = e-106
Identities = 222/488 (45%), Positives = 311/488 (63%), Gaps = 50/488 (10%)
Query: 15 GNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVC--------------GGFR 60
GNFS SA PR + + + G RG GFGS S+ GG R
Sbjct: 14 GNFSVHSAVVPRKAVGSLASYCAAG----RGAGAGFGSRSLYSLGGNRRISFNVAGGGVR 69
Query: 61 AGSCG--RSFGY---RSGGVCGP-------SPPCITT--------VSVNESLLTPLNLEI 100
AG G GY R+ G G P C++ V+VN+SLL PLN+E+
Sbjct: 70 AGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVEL 129
Query: 101 DPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEP 158
DP Q V+ +E+EQIK LN +FA+FIDKVRFLEQQN++LETK + Q + C+ NLEP
Sbjct: 130 DPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEP 189
Query: 159 LFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKK 218
+ GYI LR++ E + D RL SEL +++++E YKK+YE E+ R TAENEFV LKK
Sbjct: 190 ILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKK 249
Query: 219 DVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDC 278
D D AY K +L+A V++L +EI FL+ LY+ EI +Q+H S+TSV++ +DN+RDL++D
Sbjct: 250 DADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDS 309
Query: 279 IVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLT 338
I+AE++ Y++IA +S+AEAE+ Y++K +E++ RHG+ L+ T+ E+ ELNR+IQR+
Sbjct: 310 IIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIR 369
Query: 339 AEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVM 398
E+ N K Q + LE A+A +EQ+G+ AL DA+ KL ELEGAL +AK+++A ++REYQE+M
Sbjct: 370 CEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELM 429
Query: 399 NSKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSS---------SRGGVVCGDLCVS 448
+ KL LD+EIATYR+LLEGEE R+ E +V++ V S S GV G V+
Sbjct: 430 SLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLGASAVA 489
Query: 449 GSRPVTGS 456
GS T S
Sbjct: 490 GSSGSTQS 497
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 377 bits (967), Expect = e-104
Identities = 219/455 (48%), Positives = 305/455 (67%), Gaps = 15/455 (3%)
Query: 48 GGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPS-------PPCITTVSVNESLLTPLNLEI 100
GGFG GG R G G G GG+ GP P I VSVN+SLL PLN+++
Sbjct: 111 GGFGGGGFGGG-RFGGFGGPGGV--GGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKV 167
Query: 101 DPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ--NRECCQSNLEP 158
DP Q VK +E+EQIK+LN++FA+FIDKVRFLEQQN++L+TK + Q N NLEP
Sbjct: 168 DPEIQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEP 227
Query: 159 LFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKK 218
+F GYI++L+R + + A+ SELN++Q+++E YKKKYE+E+ R AEN+FV LKK
Sbjct: 228 IFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKK 287
Query: 219 DVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDC 278
DVD AY+ K +L++ V+ L QEI+FL+ LY+ EI + ++DT+V++ +DNSR+L++D
Sbjct: 288 DVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDS 347
Query: 279 IVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLT 338
I+AE+KAQY++IA RS+ EAE+ Y SK EE++ TV RHG++L+ K EI+ELNR+IQRL
Sbjct: 348 IIAEVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQ 407
Query: 339 AEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVM 398
E+ + K Q ++ A+A +EQ+GE AL DAR KL +LE ALQ+AK+D+A L+R+YQE+M
Sbjct: 408 GEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELM 467
Query: 399 NSKLGLDIEIATYRRLLEGEEQRLCEGVEA-VNVCVSSSR-GGVVCGDLCVSGSRPVTGS 456
N KL LD+EIATYR+LLEGEE R+ + + V V V+SS V GS S
Sbjct: 468 NVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSS 527
Query: 457 VCSAPCNGNLVVSTGLCKPCGQLNTTCGGGSCGQG 491
+G+ +G + G + GGGS G
Sbjct: 528 SGGGYSSGSSSYGSG-GRQSGSRGGSGGGGSISGG 561
>gi|194018511 keratin 77 [Homo sapiens]
Length = 578
Score = 350 bits (899), Expect = 1e-96
Identities = 197/452 (43%), Positives = 296/452 (65%), Gaps = 18/452 (3%)
Query: 4 GFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGS-------HSVC 56
G+ G GF G+ S + G R + G C G GGFG +
Sbjct: 48 GYGIHGRGF--GSRSLYNLGGSRSISINLMGRSTSGF-CQGGGVGGFGGGRGFGVGSTGA 104
Query: 57 GGFRAGSCGRS-FGYRSGGVCGPSPPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEE 111
GGF G G + FG + G+ G P C I V++N+SLL PL+LE+DP Q +K +E
Sbjct: 105 GGFGGGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQE 164
Query: 112 KEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ--NRECCQSNLEPLFAGYIETLRR 169
+EQI LN++FA+FIDKVRFLEQQN++L+TK + Q N +NLEPL YI LRR
Sbjct: 165 REQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRR 224
Query: 170 EAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSD 229
+ + + A+ R +E+ +Q+V+E YK KYE+E+ R +EN+FV LKKDVD AY+ K D
Sbjct: 225 QVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVD 284
Query: 230 LEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDD 289
LE+ V+ L E++FL+ L+ E+ +Q+HISDT+V++ +DN+R L++D I+ ++ QY+
Sbjct: 285 LESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYEL 344
Query: 290 IATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNS 349
IA RS+ EAE+ Y++K +E++ T RHG+ L+ +K EI ELNR +QRL AE+ N K Q
Sbjct: 345 IAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIE 404
Query: 350 KLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIA 409
++++ ++ +E++GE AL DA KL +LE ALQ++K+++A L+R+YQ ++ KL LD+EIA
Sbjct: 405 QMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIA 464
Query: 410 TYRRLLEGEEQRLCEGVEA-VNVCVSSSRGGV 440
TYR+LLEGEE R+ +++ V++ V +S+ V
Sbjct: 465 TYRQLLEGEESRMSGELQSHVSISVQNSQVSV 496
>gi|89357932 keratin 5b [Homo sapiens]
Length = 520
Score = 345 bits (885), Expect = 5e-95
Identities = 212/495 (42%), Positives = 300/495 (60%), Gaps = 21/495 (4%)
Query: 17 FSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGR---SFGYRSG 73
FS SAC R RG R L G G GS GR FG SG
Sbjct: 12 FSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEWSG 71
Query: 74 G----VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKV 129
G +C P I V++N++LLTPL +EIDP Q V+ +E ++I++LN++FA+FIDKV
Sbjct: 72 GPGLSLCPPGG--IQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKV 129
Query: 130 RFLEQQNKLLETKLQFYQNRECC--QSNLEPLFAGYIETLRREAECVEADSGRLASELNH 187
RFLEQQNK+LETK Q + Q LEP+F ++ LR++ E ++ + G L +EL
Sbjct: 130 RFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKA 189
Query: 188 VQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRL 247
++ E YK KYEEE RAT EN+FV LKKDVD +L K +LE +EAL + + FL+ L
Sbjct: 190 CRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHL 249
Query: 248 YEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCE 307
EEE+ LQ+ SDTSVV+ +DN+R L+ I+ E++A+Y++IA S+AEAE+ Y++K +
Sbjct: 250 NEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQ 309
Query: 308 EMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALS 367
E++ + HG+ ++ TK +I++L++ IQRL ++ EN K QN+ L+AA+ +EQ+GE AL
Sbjct: 310 ELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALK 369
Query: 368 DARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVE 427
DA+ K+ ELE AL+ AKQ++A L+ EYQE+ ++KL LD+EIATYRRLLEGEE R+ G
Sbjct: 370 DAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRM-SGEC 428
Query: 428 AVNVCVSSSRGGVV--------CGDLCVSGS-RPVTGSVCSAPCNGNLVVSTGLCKPCGQ 478
V +SS G V G C GS + GS C++ G + G K
Sbjct: 429 TSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDPVL 488
Query: 479 LNTTCGGGSCGQGRH 493
+ + G S G H
Sbjct: 489 DSCSVSGSSAGSSCH 503
>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
Length = 469
Score = 331 bits (849), Expect = 8e-91
Identities = 183/386 (47%), Positives = 255/386 (66%), Gaps = 48/386 (12%)
Query: 57 GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 113
GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+ +E+E
Sbjct: 68 GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127
Query: 114 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFAGYIETLRREA 171
QIK+LN++FA+FIDKVRFLEQQN++LETK Q + C+ NLEP++ GYI L+++
Sbjct: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187
Query: 172 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLE 231
E + D RL SEL ++Q+++E YKK+YE E+ R AENEFV LKKDVD AY+ K +L+
Sbjct: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247
Query: 232 ANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIA 291
A V++L EI F + LYE EI +QSHISDTS+V+ +DN+RDL++D I+AE++AQY++IA
Sbjct: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307
Query: 292 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 351
+S+AEAE+ Y++KC + L
Sbjct: 308 LKSKAEAETLYQTKCAD------------------------------------------L 325
Query: 352 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 411
E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 326 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 385
Query: 412 RRLLEGEEQRLC-EGVEAVNVCVSSS 436
R+LLE EE R+ E +V++ V SS
Sbjct: 386 RKLLESEECRMSGEYPNSVSISVISS 411
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,672,374
Number of Sequences: 37866
Number of extensions: 863823
Number of successful extensions: 5771
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 161
Number of HSP's successfully gapped in prelim test: 455
Number of HSP's that attempted gapping in prelim test: 4103
Number of HSP's gapped (non-prelim): 1537
length of query: 493
length of database: 18,247,518
effective HSP length: 106
effective length of query: 387
effective length of database: 14,233,722
effective search space: 5508450414
effective search space used: 5508450414
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.