Guide to the Human Genome
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Search of human proteins with 169790841

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169790841 keratin 83 [Homo sapiens]
         (493 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169790841 keratin 83 [Homo sapiens]                                997   0.0  
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   939   0.0  
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   872   0.0  
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   872   0.0  
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   872   0.0  
gi|14318422 keratin 86 [Homo sapiens]                                 872   0.0  
gi|4504935 keratin 85 [Homo sapiens]                                  783   0.0  
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    540   e-153
gi|27477127 keratin 82 [Homo sapiens]                                 522   e-148
gi|119395754 keratin 5 [Homo sapiens]                                 428   e-120
gi|5031839 keratin 6A [Homo sapiens]                                  422   e-118
gi|153791158 keratin 75 [Homo sapiens]                                420   e-117
gi|119703753 keratin 6B [Homo sapiens]                                420   e-117
gi|155969697 keratin 6C [Homo sapiens]                                420   e-117
gi|4504919 keratin 8 [Homo sapiens]                                   411   e-115
gi|109148552 keratin 3 [Homo sapiens]                                 405   e-113
gi|67782365 keratin 7 [Homo sapiens]                                  402   e-112
gi|109255249 keratin 4 [Homo sapiens]                                 401   e-112
gi|28173564 keratin 73 [Homo sapiens]                                 400   e-111
gi|15618995 keratin 71 [Homo sapiens]                                 399   e-111
gi|153791670 keratin 76 [Homo sapiens]                                394   e-109
gi|119395750 keratin 1 [Homo sapiens]                                 392   e-109
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       387   e-108
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      387   e-108
gi|32567786 keratin 6L [Homo sapiens]                                 385   e-107
gi|148612803 keratin 6 irs4 [Homo sapiens]                            381   e-106
gi|47132620 keratin 2 [Homo sapiens]                                  377   e-104
gi|194018511 keratin 77 [Homo sapiens]                                350   1e-96
gi|89357932 keratin 5b [Homo sapiens]                                 345   5e-95
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      331   8e-91

>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  997 bits (2578), Expect = 0.0
 Identities = 493/493 (100%), Positives = 493/493 (100%)

Query: 1   MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60
           MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR
Sbjct: 1   MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60

Query: 61  AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120
           AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS
Sbjct: 61  AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120

Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180
           RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR
Sbjct: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180

Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240
           LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE
Sbjct: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240

Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300
           IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES
Sbjct: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300

Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360
           WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ
Sbjct: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360

Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420
           QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ
Sbjct: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420

Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCGQLN 480
           RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCGQLN
Sbjct: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCGQLN 480

Query: 481 TTCGGGSCGQGRH 493
           TTCGGGSCGQGRH
Sbjct: 481 TTCGGGSCGQGRH 493


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  939 bits (2428), Expect = 0.0
 Identities = 468/491 (95%), Positives = 473/491 (96%), Gaps = 5/491 (1%)

Query: 1   MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60
           MTCG      GF    FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR
Sbjct: 1   MTCG-----SGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55

Query: 61  AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120
           AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS
Sbjct: 56  AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115

Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180
           RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR
Sbjct: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175

Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240
           LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE
Sbjct: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235

Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300
           IDFLRRLYEEEI ILQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES
Sbjct: 236 IDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295

Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360
           WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ
Sbjct: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355

Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420
           QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ
Sbjct: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415

Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCGQLN 480
           RLCEG+ AVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGN+ VSTGLC PCGQLN
Sbjct: 416 RLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLN 475

Query: 481 TTCGGGSCGQG 491
           TTCGGGSCG G
Sbjct: 476 TTCGGGSCGVG 486


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  872 bits (2253), Expect = 0.0
 Identities = 445/490 (90%), Positives = 456/490 (93%), Gaps = 9/490 (1%)

Query: 1   MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60
           MTCG     CG R   FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR
Sbjct: 1   MTCGSY---CGGRA--FSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55

Query: 61  AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120
           AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS
Sbjct: 56  AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115

Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180
           RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR
Sbjct: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175

Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240
           LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE
Sbjct: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235

Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300
           IDFLRRLYEEEIR+LQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES
Sbjct: 236 IDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295

Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360
           WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ
Sbjct: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355

Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420
           QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ
Sbjct: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415

Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNLVV-STGLCKPCGQ 478
           RLCEGV +VNVCVSSSRGGVVCGDLC S + PV  + V S P N N+VV +T  C P  +
Sbjct: 416 RLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR 475

Query: 479 LNTTCGGGSC 488
           +     GGSC
Sbjct: 476 VGVC--GGSC 483


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  872 bits (2253), Expect = 0.0
 Identities = 445/490 (90%), Positives = 456/490 (93%), Gaps = 9/490 (1%)

Query: 1   MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60
           MTCG     CG R   FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR
Sbjct: 1   MTCGSY---CGGRA--FSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55

Query: 61  AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120
           AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS
Sbjct: 56  AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115

Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180
           RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR
Sbjct: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175

Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240
           LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE
Sbjct: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235

Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300
           IDFLRRLYEEEIR+LQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES
Sbjct: 236 IDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295

Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360
           WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ
Sbjct: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355

Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420
           QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ
Sbjct: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415

Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNLVV-STGLCKPCGQ 478
           RLCEGV +VNVCVSSSRGGVVCGDLC S + PV  + V S P N N+VV +T  C P  +
Sbjct: 416 RLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR 475

Query: 479 LNTTCGGGSC 488
           +     GGSC
Sbjct: 476 VGVC--GGSC 483


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  872 bits (2253), Expect = 0.0
 Identities = 445/490 (90%), Positives = 456/490 (93%), Gaps = 9/490 (1%)

Query: 1   MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60
           MTCG     CG R   FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR
Sbjct: 1   MTCGSY---CGGRA--FSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55

Query: 61  AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120
           AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS
Sbjct: 56  AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115

Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180
           RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR
Sbjct: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175

Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240
           LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE
Sbjct: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235

Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300
           IDFLRRLYEEEIR+LQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES
Sbjct: 236 IDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295

Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360
           WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ
Sbjct: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355

Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420
           QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ
Sbjct: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415

Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNLVV-STGLCKPCGQ 478
           RLCEGV +VNVCVSSSRGGVVCGDLC S + PV  + V S P N N+VV +T  C P  +
Sbjct: 416 RLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR 475

Query: 479 LNTTCGGGSC 488
           +     GGSC
Sbjct: 476 VGVC--GGSC 483


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  872 bits (2253), Expect = 0.0
 Identities = 445/490 (90%), Positives = 456/490 (93%), Gaps = 9/490 (1%)

Query: 1   MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60
           MTCG     CG R   FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR
Sbjct: 1   MTCGSY---CGGRA--FSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55

Query: 61  AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120
           AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS
Sbjct: 56  AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115

Query: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180
           RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR
Sbjct: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175

Query: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240
           LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE
Sbjct: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235

Query: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300
           IDFLRRLYEEEIR+LQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES
Sbjct: 236 IDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295

Query: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360
           WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ
Sbjct: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355

Query: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420
           QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ
Sbjct: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415

Query: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNLVV-STGLCKPCGQ 478
           RLCEGV +VNVCVSSSRGGVVCGDLC S + PV  + V S P N N+VV +T  C P  +
Sbjct: 416 RLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR 475

Query: 479 LNTTCGGGSC 488
           +     GGSC
Sbjct: 476 VGVC--GGSC 483


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  783 bits (2023), Expect = 0.0
 Identities = 408/500 (81%), Positives = 438/500 (87%), Gaps = 20/500 (4%)

Query: 7   SIGCGFRPGNFSCVSACGPRP-SRCCITAAPYRGISCYRGLTGGFGSHSVC--------- 56
           S GCG    NFS  SA  P+  +RCCI+AAPYRG+SCYRGLTG FGS S+C         
Sbjct: 9   SSGCGVTR-NFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTG-FGSRSLCNLGSCGPRI 66

Query: 57  --GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ 114
             GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ
Sbjct: 67  AVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ 126

Query: 115 IKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECV 174
           IKSLNSRFAAFIDKVRFLEQQNKLLETK QFYQN+ CC+SNLEPLF+GYIETLRREAECV
Sbjct: 127 IKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETLRREAECV 186

Query: 175 EADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANV 234
           EADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFV LKKDVDCAYLRKSDLEANV
Sbjct: 187 EADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANV 246

Query: 235 EALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRS 294
           EAL++E  FLRRLYEEEIR+LQ+HISDTSV+VK+DNSRDLNMDCI+AEIKAQYDD+A+RS
Sbjct: 247 EALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRS 306

Query: 295 RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAA 354
           RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE+ENAKCQ +KLEAA
Sbjct: 307 RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAA 366

Query: 355 VAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRL 414
           VA++EQQGEAALSDARCKLAELEGALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRL
Sbjct: 367 VAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRL 426

Query: 415 LEGEEQRLCEGVEAVNVCVSSSRGGVVCGDLCVSGS--RPVTGSVCSAPCNGNLVVSTGL 472
           LEGEE RLCEGV +VNVCVSSSRGGV CG L  S +  R +T S  SA      VV+   
Sbjct: 427 LEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTPGRQIT-SGPSAIGGSITVVAPDS 485

Query: 473 CKPCGQLNTTCGGGSCGQGR 492
           C PC   +++    SCG  R
Sbjct: 486 CAPCQPRSSSF---SCGSSR 502


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  540 bits (1391), Expect = e-153
 Identities = 290/468 (61%), Positives = 360/468 (76%), Gaps = 11/468 (2%)

Query: 20  VSACGPRPSRCCIT--AAPYRGISCYRGLTGGFGSHSVCG-GFRAGSC------GRSFGY 70
           ++A G RP  C +   A    G    RG+  G  + S  G GF AGS       G  FGY
Sbjct: 65  IAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGY 124

Query: 71  RSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVR 130
           R GGV  P+ P IT V+VN+SLLTPLNLEIDPNAQ VK++EKEQIK+LN++FA+FIDKVR
Sbjct: 125 RVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVR 184

Query: 131 FLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQE 190
           FLEQQNKLLETK  F Q ++C +SNLEPLF  YI  LRR+ E + +D  RL +E NH+Q+
Sbjct: 185 FLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQD 244

Query: 191 VLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 250
           VLEG+KKKYEEEV  RA AENEFVALKKDVD A++ KSDLEANV+ L QEIDFL+ LY E
Sbjct: 245 VLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYME 304

Query: 251 EIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMK 310
           EI++LQSHIS+TSV+VK+DNSRDLN+D I+AE+KAQY+++A RSRA+AE+WY++K EEM+
Sbjct: 305 EIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQ 364

Query: 311 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 370
            T  +H + LR  + EINEL R+IQRL AE+E+AK Q +KLEAAVA++EQQGEA LSDA+
Sbjct: 365 VTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAK 424

Query: 371 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVEAVN 430
           CKLA+LE ALQ+AKQDMA  + EYQE+MN+KLGLDIEIATYRRLLEGEE RLCEGV  VN
Sbjct: 425 CKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVN 484

Query: 431 VCVSSSRGGVVCG-DLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCG 477
           + VSSSRGG+VCG +  V+GS    G V  +  + ++  ++G+   CG
Sbjct: 485 ISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSG-SSSVCATSGVLASCG 531


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  522 bits (1345), Expect = e-148
 Identities = 296/503 (58%), Positives = 356/503 (70%), Gaps = 34/503 (6%)

Query: 12  FRPGN------FSCVSACGPRP-SRCCITAAPYRGISCYRGLT--GGFGSHSVCG-GFR- 60
           F+PG+      FS  SA  PR  +   ++  P R     RGL   G  GS S+C  GF  
Sbjct: 6   FQPGSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRP-GGGRGLRALGCLGSRSLCNVGFGR 64

Query: 61  ---AGSCGRS---FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ 114
              A  CG +   FGYR G  CGPS  CIT V++NESLL PL LEIDP  Q VK++EKEQ
Sbjct: 65  PRVASRCGGTLPGFGYRLGATCGPSA-CITPVTINESLLVPLALEIDPTVQRVKRDEKEQ 123

Query: 115 IKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECV 174
           IK LN+RFA+FI+KVRFLEQ+NKLLETK  F Q + CCQ+N+EP+F GYI  LRR+ +CV
Sbjct: 124 IKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCV 183

Query: 175 EADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANV 234
             D  RL SEL  +Q  LEGYKKKYEEE++LR   ENEFVALKKDVD A+L K+DLE N 
Sbjct: 184 SGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNA 243

Query: 235 EALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRS 294
           EAL+QEIDFL+ LYEEEI +LQS IS+TSV+VK+DNSR+L++D I+AEIKAQYDDIA+RS
Sbjct: 244 EALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRS 303

Query: 295 RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAA 354
           +AEAE+WY+ + EE++ T   H + LR  K EI E+N++IQRL  E EN K Q  KLE A
Sbjct: 304 KAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGA 363

Query: 355 VAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRL 414
           +A++EQQGEAAL+DA+CKLA LE ALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRL
Sbjct: 364 IAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRL 423

Query: 415 LEGEEQRLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSV-----CSAPCNGNLVVS 469
           LEGEE RLCEG+  VN+ VSSS+G  +     VS     TG +     CS    G L V 
Sbjct: 424 LEGEEHRLCEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGELYVP 483

Query: 470 TGLCKPCGQLNTTCGGGSCGQGR 492
              C+P G L       SCG GR
Sbjct: 484 ---CEPQGLL-------SCGSGR 496


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  428 bits (1101), Expect = e-120
 Identities = 229/401 (57%), Positives = 300/401 (74%), Gaps = 9/401 (2%)

Query: 45  GLTGGFGSHSVCGGFRAGSCGRSFGYR-SGGVCGPS-PPC----ITTVSVNESLLTPLNL 98
           G  GG GS    GG   G  G   G    GG  GP  P C    I  V+VN+SLLTPLNL
Sbjct: 96  GFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 155

Query: 99  EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 156
           +IDP+ Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK    Q +  +  + NL
Sbjct: 156 QIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 215

Query: 157 EPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVAL 216
           EPLF  YI  LRR+ + +  + GRL SEL ++Q+++E +K KYE+E+  R TAENEFV L
Sbjct: 216 EPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVML 275

Query: 217 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNM 276
           KKDVD AY+ K +LEA V+AL+ EI+F++  ++ E+  +Q+H+SDTSVV+ +DN+R+L++
Sbjct: 276 KKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDL 335

Query: 277 DCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 336
           D I+AE+KAQY++IA RSR EAESWY++K EE++ T  RHG+ LR TK EI+E+NRMIQR
Sbjct: 336 DSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQR 395

Query: 337 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 396
           L AE++N K Q + L+ A+A +EQ+GE AL DAR KLAELE ALQKAKQDMA L+REYQE
Sbjct: 396 LRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQE 455

Query: 397 VMNSKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSSS 436
           +MN+KL LD+EIATYR+LLEGEE RL  EGV  VN+ V +S
Sbjct: 456 LMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTS 496


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  422 bits (1085), Expect = e-118
 Identities = 250/516 (48%), Positives = 331/516 (64%), Gaps = 33/516 (6%)

Query: 4   GFNSIGCGFRPGNFSCVSACGPRP--SRCCITAAPYRGISCYRG---LTGGFGSHSVCGG 58
           GF+S+      G+     ACG     SR        + IS   G   ++GG+GS +  G 
Sbjct: 32  GFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAG-GS 90

Query: 59  FRAGSCGRSFGYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNL 98
           +  G  G  FG+                +GG  GP  P C    I  V+VN+SLLTPLNL
Sbjct: 91  YGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 150

Query: 99  EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 156
           +IDP  Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +  +  + NL
Sbjct: 151 QIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNL 210

Query: 157 EPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVAL 216
           EPLF  YI  LRR+ + +  + GRL SEL  +Q+++E +K KYE+E+  R  AENEFV L
Sbjct: 211 EPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTL 270

Query: 217 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNM 276
           KKDVD AY+ K +L+A  + L  EI+FLR LY+ E+  +Q+HISDTSVV+ +DN+R+L++
Sbjct: 271 KKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDL 330

Query: 277 DCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 336
           D I+AE+KAQY++IA RSRAEAESWY++K EE++ T  RHG+ LR TK+EI E+NRMIQR
Sbjct: 331 DSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQR 390

Query: 337 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 396
           L +E+++ K Q + L+AA+A +EQ+GE AL DA+ KL  LE ALQKAKQD+A L++EYQE
Sbjct: 391 LRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQE 450

Query: 397 VMNSKLGLDIEIATYRRLLEGEEQRL-CEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTG 455
           +MN KL LD+EIATYR+LLEGEE RL  EGV  VN+ V  S      G     GS    G
Sbjct: 451 LMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLG 510

Query: 456 SVCSAPCNGNLVVSTGLCKPCGQL----NTTCGGGS 487
              S      L V  G     G+      ++ GGGS
Sbjct: 511 GGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGS 546


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  420 bits (1080), Expect = e-117
 Identities = 244/462 (52%), Positives = 315/462 (68%), Gaps = 32/462 (6%)

Query: 39  GISCYRGLTGGFGSH-SVCGGFRAGSCGRSFGYRSGGVCGPS-PPC----ITTVSVNESL 92
           G SC  G  G   +   V  GF  G      G   GG  GPS P C    I  V+VN+SL
Sbjct: 77  GSSCRSGFGGRASNRFGVNSGFGYG------GGVGGGFSGPSFPVCPPGGIQEVTVNQSL 130

Query: 93  LTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--E 150
           LTPL+L+IDP  Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +   
Sbjct: 131 LTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSR 190

Query: 151 CCQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAE 210
             + NLEPLF  Y   LRR+ E +  + GRL +EL ++Q+V+E +K +YE+E+  R  AE
Sbjct: 191 TVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAE 250

Query: 211 NEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDN 270
           NEFVALKKDVD AY+ K +LEA V++L +EI+F+  +++ E+  LQ+ + DTSVV+ +DN
Sbjct: 251 NEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDN 310

Query: 271 SRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINEL 330
           +R+L++D I+AE+KAQY+DIA RSRAEAESWY++K EE++ T  RHG+ LR TK+EI+E+
Sbjct: 311 NRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEM 370

Query: 331 NRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACL 390
           NRMIQRL AE+++ K Q S L+ A+A +EQ+GE AL DAR KL +LE ALQKAKQDMA L
Sbjct: 371 NRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARL 430

Query: 391 IREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSSSRGGVVCGDLCVSG 449
           +REYQE+MN KL LD+EIATYR+LLEGEE RL  EGV  VN+ V +S      G    SG
Sbjct: 431 LREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYG----SG 486

Query: 450 SRPVTGSVCSAPCNGNLVVSTGLCKPCGQLNTTCGGGSCGQG 491
                    S+   GNL    GL    G   TT GG S G G
Sbjct: 487 ---------SSIGGGNL----GLGGGSGYSFTTSGGHSLGAG 515


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  420 bits (1080), Expect = e-117
 Identities = 250/516 (48%), Positives = 331/516 (64%), Gaps = 33/516 (6%)

Query: 4   GFNSIGCGFRPGNFSCVSACGPRP--SRCCITAAPYRGISCYRG---LTGGFGSHSVCGG 58
           GF+SI      G+     ACG     SR        + IS   G   ++GG+GS +  G 
Sbjct: 32  GFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAG-GS 90

Query: 59  FRAGSCGRSFGYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNL 98
           +  G  G  FG+                +GG  GP  P C    I  V+VN+SLLTPLNL
Sbjct: 91  YGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 150

Query: 99  EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 156
           +IDP  Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK    Q +  +  + NL
Sbjct: 151 QIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 210

Query: 157 EPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVAL 216
           EPLF  YI  LRR+ + +  + GRL SEL ++Q+++E  K KYE+E+  R  AENEFV L
Sbjct: 211 EPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTL 270

Query: 217 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNM 276
           KKDVD AY+ K +L+A  + L  EI+FLR LY+ E+  +Q+HISDTSVV+ +DN+R+L++
Sbjct: 271 KKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDL 330

Query: 277 DCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 336
           D I+AE+KAQY++IA RSRAEAESWY++K EE++ T  RHG+ LR TK+EI E+NRMIQR
Sbjct: 331 DSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEIAEINRMIQR 390

Query: 337 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 396
           L +E+++ K Q + L+AA+A +EQ+GE AL DA+ KL  LE ALQKAKQD+A L++EYQE
Sbjct: 391 LRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQE 450

Query: 397 VMNSKLGLDIEIATYRRLLEGEEQRL-CEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTG 455
           +MN KL LD+EIATYR+LLEGEE RL  EGV  VN+ V  S      G     GS    G
Sbjct: 451 LMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLG 510

Query: 456 SVCSAPCNGNLVVSTGLCKPCGQLN----TTCGGGS 487
              S      L V  G     G+      ++ GGGS
Sbjct: 511 GGSSYSYGSGLGVGGGFSSSSGRATGGGLSSVGGGS 546


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  420 bits (1079), Expect = e-117
 Identities = 250/516 (48%), Positives = 331/516 (64%), Gaps = 33/516 (6%)

Query: 4   GFNSIGCGFRPGNFSCVSACGPRP--SRCCITAAPYRGISCYRG---LTGGFGSHSVCGG 58
           GF+SI      G+     ACG     SR        + IS   G   ++GG+GS +  G 
Sbjct: 32  GFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAG-GS 90

Query: 59  FRAGSCGRSFGYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNL 98
           +  G  G  FG+                +GG  GP  P C    I  V+VN+SLLTPLNL
Sbjct: 91  YGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 150

Query: 99  EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 156
           +IDP  Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK    Q +  +  + NL
Sbjct: 151 QIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 210

Query: 157 EPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVAL 216
           EPLF  YI  LRR+ + +  + GRL SEL ++Q+++E  K KYE+E+  R  AENEFV L
Sbjct: 211 EPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTL 270

Query: 217 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNM 276
           KKDVD AY+ K +L+A  + L  EI+FLR LY+ E+  +Q+HISDTSVV+ +DN+R+L++
Sbjct: 271 KKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDL 330

Query: 277 DCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 336
           D I+AE+KAQY++IA RSRAEAESWY++K EE++ T  RHG+ LR TK+EI E+NRMIQR
Sbjct: 331 DSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQR 390

Query: 337 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 396
           L +E+++ K Q + L+AA+A +EQ+GE AL DA+ KL  LE ALQKAKQD+A L++EYQE
Sbjct: 391 LRSEIDHVKKQCASLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQE 450

Query: 397 VMNSKLGLDIEIATYRRLLEGEEQRL-CEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTG 455
           +MN KL LD+EIATYR+LLEGEE RL  EGV  VNV V  S      G     GS    G
Sbjct: 451 LMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNVSVVQSTISSGYGGASGVGSGLGLG 510

Query: 456 SVCSAPCNGNLVVSTGLCKPCGQL----NTTCGGGS 487
              S      L +  G     G+      ++ GGGS
Sbjct: 511 GGSSYSYGSGLGIGGGFSSSSGRAIGGGLSSVGGGS 546


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  411 bits (1056), Expect = e-115
 Identities = 218/396 (55%), Positives = 286/396 (72%), Gaps = 1/396 (0%)

Query: 44  RGLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPC-ITTVSVNESLLTPLNLEIDP 102
           R  T G GS      F         G   GG  G S    IT V+VN+SLL+PL LE+DP
Sbjct: 23  RSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGGITAVTVNQSLLSPLVLEVDP 82

Query: 103 NAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAG 162
           N Q V+ +EKEQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q ++  +SN++ +F  
Sbjct: 83  NIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKTARSNMDNMFES 142

Query: 163 YIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDC 222
           YI  LRR+ E +  +  +L +EL ++Q ++E +K KYE+E+  R   ENEFV +KKDVD 
Sbjct: 143 YINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDE 202

Query: 223 AYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAE 282
           AY+ K +LE+ +E L  EI+FLR+LYEEEIR LQS ISDTSVV+ +DNSR L+MD I+AE
Sbjct: 203 AYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAE 262

Query: 283 IKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVE 342
           +KAQY+DIA RSRAEAES Y+ K EE+++   +HG+ LRRTK EI+E+NR I RL AE+E
Sbjct: 263 VKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIE 322

Query: 343 NAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKL 402
             K Q + LEAA+A +EQ+GE A+ DA  KL+ELE ALQ+AKQDMA  +REYQE+MN KL
Sbjct: 323 GLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLREYQELMNVKL 382

Query: 403 GLDIEIATYRRLLEGEEQRLCEGVEAVNVCVSSSRG 438
            LDIEIATYR+LLEGEE RL  G++ +++   ++ G
Sbjct: 383 ALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSG 418


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  405 bits (1041), Expect = e-113
 Identities = 219/397 (55%), Positives = 286/397 (72%), Gaps = 11/397 (2%)

Query: 45  GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNA 104
           G  GGFG     GG   GS G   G+  GG     P  I  V++N+SLL PLN+EIDP  
Sbjct: 138 GGPGGFGGSGGFGG--PGSLGSPGGFGPGGF----PGGIQEVTINQSLLQPLNVEIDPQI 191

Query: 105 QCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ----SNLEPLF 160
             VK +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +        +NLEPLF
Sbjct: 192 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLF 251

Query: 161 AGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDV 220
             +I  LR   + +  + GRL SEL ++++++E +KKKYE+E+  R  AENEFV LKKDV
Sbjct: 252 ENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDV 311

Query: 221 DCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIV 280
           D AY+ K +L+A V+ALI EIDFLR LY+ E+  +QSHISDTSVV+ +DN+R L++D I+
Sbjct: 312 DSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSII 371

Query: 281 AEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE 340
           AE++AQY+DIA RS+AEAE+ Y++K  E++ T  RHG+ LR TK EI ELNRMIQRL AE
Sbjct: 372 AEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAE 431

Query: 341 VENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNS 400
           +E  K QN+ L+ A+A++EQ GE AL DA  KL EL+ ALQ+AK D+A L+R+YQE+MN 
Sbjct: 432 IEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNV 491

Query: 401 KLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSSS 436
           KL LD+EIATYR+LLEGEE R+  E   AV++ V SS
Sbjct: 492 KLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSS 528


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  402 bits (1032), Expect = e-112
 Identities = 220/398 (55%), Positives = 287/398 (72%), Gaps = 6/398 (1%)

Query: 48  GGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 107
           GG GS S+ G    G+       RS    GP    I  V++N+SLL PL L+ DP+ Q V
Sbjct: 32  GGLGSSSLYG---LGASRPRVAVRSA-YGGPVGAGIREVTINQSLLAPLRLDADPSLQRV 87

Query: 108 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEP-LFAGYIET 166
           +QEE EQIK+LN++FA+FIDKVRFLEQQNKLLETK    Q ++  +S+  P +F   I  
Sbjct: 88  RQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRLPDIFEAQIAG 147

Query: 167 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLR 226
           LR + E ++ D GRL +EL  +Q+V+E +K KYE+E+  R  AENEFV LKKDVD AY+ 
Sbjct: 148 LRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMS 207

Query: 227 KSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQ 286
           K +LEA V+AL  EI+FLR L E E+  LQS ISDTSVV+ +DNSR L++D I+AE+KAQ
Sbjct: 208 KVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQ 267

Query: 287 YDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 346
           Y+++A  SRAEAE+WY++K E ++A   +HG+ LR T+ EI+E+NR IQRL AE++N K 
Sbjct: 268 YEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKN 327

Query: 347 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 406
           Q +KLEAA+A++E++GE AL DAR K  ELE ALQ+ KQDMA  +REYQE+M+ KL LDI
Sbjct: 328 QRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDI 387

Query: 407 EIATYRRLLEGEEQRLC-EGVEAVNVCVSSSRGGVVCG 443
           EIATYR+LLEGEE RL  +GV AVN+ V +S GG   G
Sbjct: 388 EIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSG 425


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  401 bits (1030), Expect = e-112
 Identities = 227/463 (49%), Positives = 310/463 (66%), Gaps = 21/463 (4%)

Query: 2   TCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRG-----LTGGFGSHSVC 56
           +CG   +G G R G FS VS  G    RC       R +   RG     ++        C
Sbjct: 90  SCGSAIVGGGKR-GAFSSVSMSGGA-GRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGAC 147

Query: 57  ----GGFRAGSCGRSFGYRSGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCV 107
               GGF  G  G  FG    G  GP  P C    I  V++N+SLLTPL++EIDP  Q V
Sbjct: 148 FGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDPEIQKV 207

Query: 108 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFAGYIE 165
           + EE+EQIK LN++FA+FIDKV+FLEQQNK+LETK    Q +    S  NLEPLF  Y+ 
Sbjct: 208 RTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFETYLS 267

Query: 166 TLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYL 225
            LR++ + +  D GRL SEL  +Q+ +E +K KYEEE+  R  AEN+FV LKKDVD AYL
Sbjct: 268 VLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYL 327

Query: 226 RKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKA 285
            K +LEA V++L  EI+FL+ LY+ E+  +Q+H+SDTSVV+ +DN+R+L++D I+AE++A
Sbjct: 328 NKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRA 387

Query: 286 QYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAK 345
           QY++IA RS+AEAE+ Y++K ++++ +V +HG+ L+ TK EI ELNRMIQRL AE+EN K
Sbjct: 388 QYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIK 447

Query: 346 CQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLD 405
            Q   L+ +VA +EQ+GE AL DA  K  ELE ALQ+AK+++A ++REYQE+M+ KL LD
Sbjct: 448 KQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVKLALD 507

Query: 406 IEIATYRRLLEGEEQRL---CEGVEAVNVCVSSSRGGVVCGDL 445
           IEIATYR+LLEGEE R+   C+   +++V   S+  G + G L
Sbjct: 508 IEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGL 550


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score =  400 bits (1027), Expect = e-111
 Identities = 223/459 (48%), Positives = 308/459 (67%), Gaps = 21/459 (4%)

Query: 45  GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEID 101
           G  GG+G      G  +G  G  FG  + G   PS   P  I  V++N+SLL PLN+E+D
Sbjct: 66  GWAGGYGFGR---GRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELD 122

Query: 102 PNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPL 159
           P  Q V+ +E+EQIK LN++FA+FIDKVRFLEQQN++LETK +  Q  +   C++NLEP+
Sbjct: 123 PEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPI 182

Query: 160 FAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKD 219
             GYI  LR++ E +  D  RL SEL  V+EV+E YKK+YEEE+  R TAENEFV LKKD
Sbjct: 183 LEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKD 242

Query: 220 VDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCI 279
           VD AY  K +L+A V+AL  EI F + LYE E   +QSHISDTS+++ +DN+R+L++D I
Sbjct: 243 VDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSI 302

Query: 280 VAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTA 339
           +AE++AQY++IA +S+AEAE+ Y++K +E++    RHG+ L+ TK EI+EL R+IQRL +
Sbjct: 303 IAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRS 362

Query: 340 EVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMN 399
           E+E+ K Q + LE A+A +EQ+G+ AL DAR KL ELEGALQ+AK+++A ++REYQE+++
Sbjct: 363 EIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLS 422

Query: 400 SKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSSSRGGVVCGDLCVSG--------- 449
            KL LDIEIATYR+LLEGEE R+  E   +V++ V +S    + G     G         
Sbjct: 423 VKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTYGY 482

Query: 450 -SRPVTGSVCSAPCNGNLVVSTGLCKPCGQLNTTCGGGS 487
               V+G     P  G  V  +G C P G+  T  G  S
Sbjct: 483 WPSSVSGGYSMLP--GGCVTGSGNCSPRGEARTRLGSAS 519


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  399 bits (1024), Expect = e-111
 Identities = 224/447 (50%), Positives = 307/447 (68%), Gaps = 32/447 (7%)

Query: 44  RGLTGGFGSHSV--CGGFR----AGSCGRSFGY-----RSGGVCGP-------SPPCITT 85
           +GL+GGFGS S+   GG R    A   G+S GY     R+ G  G         P C T 
Sbjct: 37  KGLSGGFGSRSLYSLGGVRSLNVASGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTV 96

Query: 86  --------VSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNK 137
                   V+VNESLL PLN+E+DP  Q V+ +E+EQIK+LN++FA+FIDKVRFLEQQN+
Sbjct: 97  CPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQ 156

Query: 138 LLETKLQFYQNREC--CQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGY 195
           +LETK +  Q  +   C++NLEP+  GYI  LR++ E +  D  RL SEL +V++V+E Y
Sbjct: 157 VLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDY 216

Query: 196 KKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRIL 255
           KK+YEEE+  R  AENEFV LKKDVD AY  K +L+A VE++ QEI F R L+E EI  +
Sbjct: 217 KKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQI 276

Query: 256 QSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIR 315
           QSHISD SV++ +DN+R+L++D I+ E++ QY++IA +S+AEAE+ Y++K +E++    R
Sbjct: 277 QSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGR 336

Query: 316 HGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAE 375
           HG+ L+ TK EI+EL R+IQR+ +E+EN K Q S LE A+A +EQ+G+ AL DAR KL E
Sbjct: 337 HGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDE 396

Query: 376 LEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNV-CV 433
           LEGAL +AK+++A ++REYQE+M+ KL LD+EIATYR+LLE EE R+  E    V++  +
Sbjct: 397 LEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISII 456

Query: 434 SSSRGGVVCG--DLCVSGSRPVTGSVC 458
           SS+ GG V G     VSG      S C
Sbjct: 457 SSTSGGSVYGFRPSMVSGGYVANSSNC 483


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  394 bits (1012), Expect = e-109
 Identities = 228/464 (49%), Positives = 306/464 (65%), Gaps = 25/464 (5%)

Query: 45  GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNA 104
           G  GGFG   V GG   GS G   G+  GG     P  I  V VN+SLL PLN+EIDP  
Sbjct: 123 GGAGGFGGPGVFGG--PGSFGGPGGFGPGGF----PGGIQEVIVNQSLLQPLNVEIDPQI 176

Query: 105 QCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ--SNLEPLFAG 162
             VK +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK +  Q +      S+LEP F  
Sbjct: 177 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFES 236

Query: 163 YIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDC 222
           YI  L ++ + +  + G L  EL  +Q+++E +KKKYE+E+  R  AENEFV LKKDVD 
Sbjct: 237 YISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDA 296

Query: 223 AYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAE 282
           A++ K +L+A V++L  E+ FLR LYE E+  +QSH SDTSVV+ +DN+R L++  I+AE
Sbjct: 297 AFMNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAE 356

Query: 283 IKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVE 342
           ++AQY++IA RS++EAE+ Y++K  E++ T  RHG+ LR TK EI ELNRMIQRL AE+E
Sbjct: 357 VRAQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIE 416

Query: 343 NAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKL 402
           N K QN+ L+ A+A++EQ+GE AL DA  KL +L+ ALQKAK D+A L+R+YQE+MN KL
Sbjct: 417 NVKKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKL 476

Query: 403 GLDIEIATYRRLLEGEEQRLCEGVEAVNVCVS-------------SSRGGVVCGDLCVSG 449
            LD+EIATYR+LLEGEE R+    ++  VC+S             SSRG  V G +  SG
Sbjct: 477 ALDVEIATYRKLLEGEECRMSGECQSA-VCISVVSNVTSTSGSSGSSRG--VFGGVSGSG 533

Query: 450 SRPVTGSVCSAPCNGNLVVSTGLCKPCGQLNTTCGGGSCGQGRH 493
           S    G   S+  +G   VS G     G +++   GG    G +
Sbjct: 534 SGGYKGGSSSSSSSG-YGVSGGSGSGYGGVSSGSTGGRGSSGSY 576


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  392 bits (1008), Expect = e-109
 Identities = 223/448 (49%), Positives = 308/448 (68%), Gaps = 9/448 (2%)

Query: 48  GGFGSHSVCGGFRAGSCGRS-FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQC 106
           GGFGS    GGF  G  G   +G   G VC P    I  V++N+SLL PLN+EIDP  Q 
Sbjct: 120 GGFGSGG--GGFGGGGFGGGGYGGGYGPVCPPGG--IQEVTINQSLLQPLNVEIDPEIQK 175

Query: 107 VKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFAGYI 164
           VK  E+EQIKSLN++FA+FIDKVRFLEQQN++L+TK +  Q  +      NLEP F  +I
Sbjct: 176 VKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFI 235

Query: 165 ETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAY 224
             LRR  + +++D  RL SEL ++Q+++E Y+ KYE+E+  R  AENEFV +KKDVD AY
Sbjct: 236 NNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAY 295

Query: 225 LRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIK 284
           + K DL+A ++ L QEIDFL  LY+ E+  +Q+ IS+T+V++ +DN+R L++D I+AE+K
Sbjct: 296 MTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVK 355

Query: 285 AQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENA 344
           AQY+DIA +S+AEAES Y+SK EE++ T  RHG+++R +K EI+ELNR+IQRL +E++N 
Sbjct: 356 AQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNV 415

Query: 345 KCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGL 404
           K Q S L+ +++ +EQ+GE AL DA+ KL +LE ALQ+AK+D+A L+R+YQE+MN+KL L
Sbjct: 416 KKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLAL 475

Query: 405 DIEIATYRRLLEGEEQRLCEGVEAVNVCVS-SSRGGVVCGDLCVSGSRPVTGSVCSAPCN 463
           D+EIATYR LLEGEE R+  G  A NV VS S+    + G     G     GS  S+  +
Sbjct: 476 DLEIATYRTLLEGEESRM-SGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGS 534

Query: 464 GNLVVSTGLCKPCGQLNTTCGGGSCGQG 491
           G     +G     G+ +   GG S G G
Sbjct: 535 GGGSYGSGGGGGGGRGSYGSGGSSYGSG 562


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  387 bits (995), Expect = e-108
 Identities = 202/386 (52%), Positives = 285/386 (73%), Gaps = 6/386 (1%)

Query: 57  GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 113
           GG   G  G +FG    G   PS   P  I  V+VN+SLL PLN+E+DP  Q V+ +E+E
Sbjct: 68  GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127

Query: 114 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFAGYIETLRREA 171
           QIK+LN++FA+FIDKVRFLEQQN++LETK    Q  +   C+ NLEP++ GYI  L+++ 
Sbjct: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187

Query: 172 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLE 231
           E +  D  RL SEL ++Q+++E YKK+YE E+  R  AENEFV LKKDVD AY+ K +L+
Sbjct: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247

Query: 232 ANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIA 291
           A V++L  EI F + LYE EI  +QSHISDTS+V+ +DN+RDL++D I+AE++AQY++IA
Sbjct: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307

Query: 292 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 351
            +S+AEAE+ Y++K +E++ T  +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + L
Sbjct: 308 LKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADL 367

Query: 352 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 411
           E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 368 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 427

Query: 412 RRLLEGEEQRLC-EGVEAVNVCVSSS 436
           R+LLE EE R+  E   +V++ V SS
Sbjct: 428 RKLLESEECRMSGEYPNSVSISVISS 453


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  387 bits (995), Expect = e-108
 Identities = 202/386 (52%), Positives = 285/386 (73%), Gaps = 6/386 (1%)

Query: 57  GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 113
           GG   G  G +FG    G   PS   P  I  V+VN+SLL PLN+E+DP  Q V+ +E+E
Sbjct: 68  GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127

Query: 114 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFAGYIETLRREA 171
           QIK+LN++FA+FIDKVRFLEQQN++LETK    Q  +   C+ NLEP++ GYI  L+++ 
Sbjct: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187

Query: 172 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLE 231
           E +  D  RL SEL ++Q+++E YKK+YE E+  R  AENEFV LKKDVD AY+ K +L+
Sbjct: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247

Query: 232 ANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIA 291
           A V++L  EI F + LYE EI  +QSHISDTS+V+ +DN+RDL++D I+AE++AQY++IA
Sbjct: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307

Query: 292 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 351
            +S+AEAE+ Y++K +E++ T  +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + L
Sbjct: 308 LKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADL 367

Query: 352 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 411
           E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 368 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 427

Query: 412 RRLLEGEEQRLC-EGVEAVNVCVSSS 436
           R+LLE EE R+  E   +V++ V SS
Sbjct: 428 RKLLESEECRMSGEYPNSVSISVISS 453


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  385 bits (988), Expect = e-107
 Identities = 215/434 (49%), Positives = 294/434 (67%), Gaps = 31/434 (7%)

Query: 39  GISCYRGLTGGFGSHS-------------VCGGFRAGSCGRSFGYRSGGVCGPS------ 79
           G  C  G TGGFGS S             V GG   G     FG+ S    G        
Sbjct: 47  GAHCGPG-TGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTF 105

Query: 80  -PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQ 134
            P C    I  V+VN+SLLTPL++EIDP  Q V+ +E+EQIK+LN++FA+FIDKVRFLEQ
Sbjct: 106 GPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQ 165

Query: 135 QNKLLETKLQFYQ----NRECCQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQE 190
           QNK+LETK    Q    N    ++NLEPLF  Y+ ++R   + ++++ GRL SEL +VQ+
Sbjct: 166 QNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQD 225

Query: 191 VLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 250
           ++E +K KYE+E+     AENEFV LKKDVD AY+ + DL   V  L QEIDFL++LYE 
Sbjct: 226 LVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEM 285

Query: 251 EIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMK 310
           E+  +Q+H+S+T+VV+ +DN+R+L++D I+AE+KAQY+ IA RSRAEAE+WY++K EE++
Sbjct: 286 ELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQ 345

Query: 311 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 370
            T  +HG+ LR TK EI EL R IQRL  E + AK Q  +L+ A+A++EQ+GE AL DA+
Sbjct: 346 VTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQ 405

Query: 371 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVEAV 429
            KL +L+ AL +AK+D+  L+R+YQE+MN KL LD+EIATYR+LLE EE R+  E   AV
Sbjct: 406 KKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAV 465

Query: 430 NVCVSSSRGGVVCG 443
           ++ V+ +    VCG
Sbjct: 466 SISVTGN-STTVCG 478


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  381 bits (979), Expect = e-106
 Identities = 222/488 (45%), Positives = 311/488 (63%), Gaps = 50/488 (10%)

Query: 15  GNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVC--------------GGFR 60
           GNFS  SA  PR +   + +    G    RG   GFGS S+               GG R
Sbjct: 14  GNFSVHSAVVPRKAVGSLASYCAAG----RGAGAGFGSRSLYSLGGNRRISFNVAGGGVR 69

Query: 61  AGSCG--RSFGY---RSGGVCGP-------SPPCITT--------VSVNESLLTPLNLEI 100
           AG  G     GY   R+ G  G         P C++         V+VN+SLL PLN+E+
Sbjct: 70  AGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVEL 129

Query: 101 DPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEP 158
           DP  Q V+ +E+EQIK LN +FA+FIDKVRFLEQQN++LETK +  Q  +   C+ NLEP
Sbjct: 130 DPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEP 189

Query: 159 LFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKK 218
           +  GYI  LR++ E +  D  RL SEL  +++++E YKK+YE E+  R TAENEFV LKK
Sbjct: 190 ILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKK 249

Query: 219 DVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDC 278
           D D AY  K +L+A V++L +EI FL+ LY+ EI  +Q+H S+TSV++ +DN+RDL++D 
Sbjct: 250 DADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDS 309

Query: 279 IVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLT 338
           I+AE++  Y++IA +S+AEAE+ Y++K +E++    RHG+ L+ T+ E+ ELNR+IQR+ 
Sbjct: 310 IIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIR 369

Query: 339 AEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVM 398
            E+ N K Q + LE A+A +EQ+G+ AL DA+ KL ELEGAL +AK+++A ++REYQE+M
Sbjct: 370 CEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELM 429

Query: 399 NSKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSS---------SRGGVVCGDLCVS 448
           + KL LD+EIATYR+LLEGEE R+  E   +V++ V S         S  GV  G   V+
Sbjct: 430 SLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLGASAVA 489

Query: 449 GSRPVTGS 456
           GS   T S
Sbjct: 490 GSSGSTQS 497


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  377 bits (967), Expect = e-104
 Identities = 219/455 (48%), Positives = 305/455 (67%), Gaps = 15/455 (3%)

Query: 48  GGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPS-------PPCITTVSVNESLLTPLNLEI 100
           GGFG     GG R G  G   G   GG+ GP        P  I  VSVN+SLL PLN+++
Sbjct: 111 GGFGGGGFGGG-RFGGFGGPGGV--GGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKV 167

Query: 101 DPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ--NRECCQSNLEP 158
           DP  Q VK +E+EQIK+LN++FA+FIDKVRFLEQQN++L+TK +  Q  N      NLEP
Sbjct: 168 DPEIQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEP 227

Query: 159 LFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKK 218
           +F GYI++L+R  + + A+     SELN++Q+++E YKKKYE+E+  R  AEN+FV LKK
Sbjct: 228 IFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKK 287

Query: 219 DVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDC 278
           DVD AY+ K +L++ V+ L QEI+FL+ LY+ EI  +   ++DT+V++ +DNSR+L++D 
Sbjct: 288 DVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDS 347

Query: 279 IVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLT 338
           I+AE+KAQY++IA RS+ EAE+ Y SK EE++ TV RHG++L+  K EI+ELNR+IQRL 
Sbjct: 348 IIAEVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQ 407

Query: 339 AEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVM 398
            E+ + K Q   ++ A+A +EQ+GE AL DAR KL +LE ALQ+AK+D+A L+R+YQE+M
Sbjct: 408 GEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELM 467

Query: 399 NSKLGLDIEIATYRRLLEGEEQRLCEGVEA-VNVCVSSSR-GGVVCGDLCVSGSRPVTGS 456
           N KL LD+EIATYR+LLEGEE R+   + + V V V+SS     V       GS     S
Sbjct: 468 NVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSS 527

Query: 457 VCSAPCNGNLVVSTGLCKPCGQLNTTCGGGSCGQG 491
                 +G+    +G  +  G    + GGGS   G
Sbjct: 528 SGGGYSSGSSSYGSG-GRQSGSRGGSGGGGSISGG 561


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  350 bits (899), Expect = 1e-96
 Identities = 197/452 (43%), Positives = 296/452 (65%), Gaps = 18/452 (3%)

Query: 4   GFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGS-------HSVC 56
           G+   G GF  G+ S  +  G R     +      G  C  G  GGFG         +  
Sbjct: 48  GYGIHGRGF--GSRSLYNLGGSRSISINLMGRSTSGF-CQGGGVGGFGGGRGFGVGSTGA 104

Query: 57  GGFRAGSCGRS-FGYRSGGVCGPSPPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEE 111
           GGF  G  G + FG  + G+ G  P C    I  V++N+SLL PL+LE+DP  Q +K +E
Sbjct: 105 GGFGGGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQE 164

Query: 112 KEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ--NRECCQSNLEPLFAGYIETLRR 169
           +EQI  LN++FA+FIDKVRFLEQQN++L+TK +  Q  N     +NLEPL   YI  LRR
Sbjct: 165 REQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRR 224

Query: 170 EAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSD 229
           + + + A+  R  +E+  +Q+V+E YK KYE+E+  R  +EN+FV LKKDVD AY+ K D
Sbjct: 225 QVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVD 284

Query: 230 LEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDD 289
           LE+ V+ L  E++FL+ L+  E+  +Q+HISDT+V++ +DN+R L++D I+  ++ QY+ 
Sbjct: 285 LESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYEL 344

Query: 290 IATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNS 349
           IA RS+ EAE+ Y++K +E++ T  RHG+ L+ +K EI ELNR +QRL AE+ N K Q  
Sbjct: 345 IAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIE 404

Query: 350 KLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIA 409
           ++++ ++ +E++GE AL DA  KL +LE ALQ++K+++A L+R+YQ ++  KL LD+EIA
Sbjct: 405 QMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIA 464

Query: 410 TYRRLLEGEEQRLCEGVEA-VNVCVSSSRGGV 440
           TYR+LLEGEE R+   +++ V++ V +S+  V
Sbjct: 465 TYRQLLEGEESRMSGELQSHVSISVQNSQVSV 496


>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score =  345 bits (885), Expect = 5e-95
 Identities = 212/495 (42%), Positives = 300/495 (60%), Gaps = 21/495 (4%)

Query: 17  FSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGR---SFGYRSG 73
           FS  SAC  R           RG    R L    G      G   GS GR    FG  SG
Sbjct: 12  FSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEWSG 71

Query: 74  G----VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKV 129
           G    +C P    I  V++N++LLTPL +EIDP  Q V+ +E ++I++LN++FA+FIDKV
Sbjct: 72  GPGLSLCPPGG--IQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKV 129

Query: 130 RFLEQQNKLLETKLQFYQNRECC--QSNLEPLFAGYIETLRREAECVEADSGRLASELNH 187
           RFLEQQNK+LETK    Q +     Q  LEP+F   ++ LR++ E ++ + G L +EL  
Sbjct: 130 RFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKA 189

Query: 188 VQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRL 247
            ++  E YK KYEEE   RAT EN+FV LKKDVD  +L K +LE  +EAL + + FL+ L
Sbjct: 190 CRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHL 249

Query: 248 YEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCE 307
            EEE+  LQ+  SDTSVV+ +DN+R L+   I+ E++A+Y++IA  S+AEAE+ Y++K +
Sbjct: 250 NEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQ 309

Query: 308 EMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALS 367
           E++ +   HG+ ++ TK +I++L++ IQRL ++ EN K QN+ L+AA+  +EQ+GE AL 
Sbjct: 310 ELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALK 369

Query: 368 DARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVE 427
           DA+ K+ ELE AL+ AKQ++A L+ EYQE+ ++KL LD+EIATYRRLLEGEE R+  G  
Sbjct: 370 DAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRM-SGEC 428

Query: 428 AVNVCVSSSRGGVV--------CGDLCVSGS-RPVTGSVCSAPCNGNLVVSTGLCKPCGQ 478
              V +SS  G  V         G  C  GS +   GS C++   G   +  G  K    
Sbjct: 429 TSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDPVL 488

Query: 479 LNTTCGGGSCGQGRH 493
            + +  G S G   H
Sbjct: 489 DSCSVSGSSAGSSCH 503


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  331 bits (849), Expect = 8e-91
 Identities = 183/386 (47%), Positives = 255/386 (66%), Gaps = 48/386 (12%)

Query: 57  GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 113
           GG   G  G +FG    G   PS   P  I  V+VN+SLL PLN+E+DP  Q V+ +E+E
Sbjct: 68  GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127

Query: 114 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFAGYIETLRREA 171
           QIK+LN++FA+FIDKVRFLEQQN++LETK    Q  +   C+ NLEP++ GYI  L+++ 
Sbjct: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187

Query: 172 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLE 231
           E +  D  RL SEL ++Q+++E YKK+YE E+  R  AENEFV LKKDVD AY+ K +L+
Sbjct: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247

Query: 232 ANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIA 291
           A V++L  EI F + LYE EI  +QSHISDTS+V+ +DN+RDL++D I+AE++AQY++IA
Sbjct: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307

Query: 292 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 351
            +S+AEAE+ Y++KC +                                          L
Sbjct: 308 LKSKAEAETLYQTKCAD------------------------------------------L 325

Query: 352 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 411
           E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 326 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 385

Query: 412 RRLLEGEEQRLC-EGVEAVNVCVSSS 436
           R+LLE EE R+  E   +V++ V SS
Sbjct: 386 RKLLESEECRMSGEYPNSVSISVISS 411


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,672,374
Number of Sequences: 37866
Number of extensions: 863823
Number of successful extensions: 5771
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 161
Number of HSP's successfully gapped in prelim test: 455
Number of HSP's that attempted gapping in prelim test: 4103
Number of HSP's gapped (non-prelim): 1537
length of query: 493
length of database: 18,247,518
effective HSP length: 106
effective length of query: 387
effective length of database: 14,233,722
effective search space: 5508450414
effective search space used: 5508450414
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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