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Search of human proteins with 169658367
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169658367 BAH domain and coiled-coil containing 1 [Homo
sapiens]
(2608 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens] 5279 0.0
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 590 e-168
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 77 3e-13
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 75 1e-12
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 73 3e-12
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 70 2e-11
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 69 5e-11
gi|139394604 bromo adjacent homology domain containing 1 [Homo s... 69 6e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 68 1e-10
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 67 3e-10
gi|83921602 solute carrier family 38, member 10 isoform a [Homo ... 62 6e-09
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 62 6e-09
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 62 6e-09
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 62 6e-09
gi|150170670 piccolo isoform 2 [Homo sapiens] 62 7e-09
gi|150378539 piccolo isoform 1 [Homo sapiens] 62 7e-09
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 62 7e-09
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 62 1e-08
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 62 1e-08
gi|110832843 TBP-associated factor 4 [Homo sapiens] 60 2e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni... 59 5e-08
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 59 6e-08
gi|148612879 polyhomeotic like 3 [Homo sapiens] 59 6e-08
gi|47132519 Ras association and pleckstrin homology domains 1 is... 59 8e-08
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 58 1e-07
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 58 1e-07
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 58 1e-07
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 58 1e-07
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 58 1e-07
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 57 2e-07
>gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens]
Length = 2608
Score = 5279 bits (13694), Expect = 0.0
Identities = 2608/2608 (100%), Positives = 2608/2608 (100%)
Query: 1 MDGRDFAPPPHLLSERGSLGHRSAAAAARLAPAGPAAQPPAHFQPGKYFPSPLPMASHTA 60
MDGRDFAPPPHLLSERGSLGHRSAAAAARLAPAGPAAQPPAHFQPGKYFPSPLPMASHTA
Sbjct: 1 MDGRDFAPPPHLLSERGSLGHRSAAAAARLAPAGPAAQPPAHFQPGKYFPSPLPMASHTA 60
Query: 61 SSRLMGSSPASSFMGSFLTSSLGSAASTHPSGPSSSPPEQAYRGSHPTTSQIWFSHSHEA 120
SSRLMGSSPASSFMGSFLTSSLGSAASTHPSGPSSSPPEQAYRGSHPTTSQIWFSHSHEA
Sbjct: 61 SSRLMGSSPASSFMGSFLTSSLGSAASTHPSGPSSSPPEQAYRGSHPTTSQIWFSHSHEA 120
Query: 121 PGYPRFSGSLASTFLPVSHLDHHGNSNVLYGQHRFYGTQKDNFYLRNLPPQPTLLPANHN 180
PGYPRFSGSLASTFLPVSHLDHHGNSNVLYGQHRFYGTQKDNFYLRNLPPQPTLLPANHN
Sbjct: 121 PGYPRFSGSLASTFLPVSHLDHHGNSNVLYGQHRFYGTQKDNFYLRNLPPQPTLLPANHN 180
Query: 181 FPSVARAAPAHPMGSCSRDRDRGEAGSLQKGPKDFDRFLVGKELGREKAGKAAEGKERPA 240
FPSVARAAPAHPMGSCSRDRDRGEAGSLQKGPKDFDRFLVGKELGREKAGKAAEGKERPA
Sbjct: 181 FPSVARAAPAHPMGSCSRDRDRGEAGSLQKGPKDFDRFLVGKELGREKAGKAAEGKERPA 240
Query: 241 AEEDGGKERHKLVLPVPADGHCREGGPAPRGACEGRPKHLTSCLLNTKVLNGEMGRAALA 300
AEEDGGKERHKLVLPVPADGHCREGGPAPRGACEGRPKHLTSCLLNTKVLNGEMGRAALA
Sbjct: 241 AEEDGGKERHKLVLPVPADGHCREGGPAPRGACEGRPKHLTSCLLNTKVLNGEMGRAALA 300
Query: 301 SCAGGMLGRPGTGVVTSGRCAKEAAGPPEPGPAFSECLERRQMLHHTASYAGPPPPLSTA 360
SCAGGMLGRPGTGVVTSGRCAKEAAGPPEPGPAFSECLERRQMLHHTASYAGPPPPLSTA
Sbjct: 301 SCAGGMLGRPGTGVVTSGRCAKEAAGPPEPGPAFSECLERRQMLHHTASYAGPPPPLSTA 360
Query: 361 AGSFPCLQLHGGPDGLCPLQDKAPRDLKASGPTFVPSVGHLADKGRPFQAAEACAVAGEG 420
AGSFPCLQLHGGPDGLCPLQDKAPRDLKASGPTFVPSVGHLADKGRPFQAAEACAVAGEG
Sbjct: 361 AGSFPCLQLHGGPDGLCPLQDKAPRDLKASGPTFVPSVGHLADKGRPFQAAEACAVAGEG 420
Query: 421 KDRHLEGTMAPDHAAPYGVSYAHLKAEGKGERRPGGFEAALNPRLKGLDYLSSAGPEASF 480
KDRHLEGTMAPDHAAPYGVSYAHLKAEGKGERRPGGFEAALNPRLKGLDYLSSAGPEASF
Sbjct: 421 KDRHLEGTMAPDHAAPYGVSYAHLKAEGKGERRPGGFEAALNPRLKGLDYLSSAGPEASF 480
Query: 481 PGLPKSGLDKSGYFELPTSSQDCARPGHQDPLGGKAPQACCTLDKTVGKEAPAGPPGAQK 540
PGLPKSGLDKSGYFELPTSSQDCARPGHQDPLGGKAPQACCTLDKTVGKEAPAGPPGAQK
Sbjct: 481 PGLPKSGLDKSGYFELPTSSQDCARPGHQDPLGGKAPQACCTLDKTVGKEAPAGPPGAQK 540
Query: 541 VARIRHQQHLMAAEVEQGGIGAEAKRKSLELASLGYSGPHLPPWGVQAGQGTAMAISEER 600
VARIRHQQHLMAAEVEQGGIGAEAKRKSLELASLGYSGPHLPPWGVQAGQGTAMAISEER
Sbjct: 541 VARIRHQQHLMAAEVEQGGIGAEAKRKSLELASLGYSGPHLPPWGVQAGQGTAMAISEER 600
Query: 601 KAGAYLDPFGSGLQQAALLPQELPAPPDEVSAMKNLLKYSSQALVVGQKAPLVGLGGLKA 660
KAGAYLDPFGSGLQQAALLPQELPAPPDEVSAMKNLLKYSSQALVVGQKAPLVGLGGLKA
Sbjct: 601 KAGAYLDPFGSGLQQAALLPQELPAPPDEVSAMKNLLKYSSQALVVGQKAPLVGLGGLKA 660
Query: 661 SCIQQEAKFLSSKGPGQSERPDCARSREHDTTHGDGEVRQPPVGIAVALARQKDTVSRSE 720
SCIQQEAKFLSSKGPGQSERPDCARSREHDTTHGDGEVRQPPVGIAVALARQKDTVSRSE
Sbjct: 661 SCIQQEAKFLSSKGPGQSERPDCARSREHDTTHGDGEVRQPPVGIAVALARQKDTVSRSE 720
Query: 721 AAYGTNTARQGRAAPAFKGGGGPRSTHALDLEAEEERTRLCDDRLGLASRELLLQDSKDR 780
AAYGTNTARQGRAAPAFKGGGGPRSTHALDLEAEEERTRLCDDRLGLASRELLLQDSKDR
Sbjct: 721 AAYGTNTARQGRAAPAFKGGGGPRSTHALDLEAEEERTRLCDDRLGLASRELLLQDSKDR 780
Query: 781 VEFARIHPPSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTRSPSLWMGGHSYGLG 840
VEFARIHPPSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTRSPSLWMGGHSYGLG
Sbjct: 781 VEFARIHPPSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTRSPSLWMGGHSYGLG 840
Query: 841 HPALHQNLPPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADVMDQASLW 900
HPALHQNLPPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADVMDQASLW
Sbjct: 841 HPALHQNLPPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADVMDQASLW 900
Query: 901 PPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLEEPAQ 960
PPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLEEPAQ
Sbjct: 901 PPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLEEPAQ 960
Query: 961 EKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAPCTLNV 1020
EKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAPCTLNV
Sbjct: 961 EKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAPCTLNV 1020
Query: 1021 CPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNL 1080
CPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNL
Sbjct: 1021 CPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNL 1080
Query: 1081 EDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERG 1140
EDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERG
Sbjct: 1081 EDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERG 1140
Query: 1141 PQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGEQGPSSGASS 1200
PQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGEQGPSSGASS
Sbjct: 1141 PQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGEQGPSSGASS 1200
Query: 1201 QVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGL 1260
QVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGL
Sbjct: 1201 QVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGL 1260
Query: 1261 DALVAATINLGDLPSDSPPDPQPPAASGPPSTVPLPHSSGIHGIALLSELADLAIQRQRS 1320
DALVAATINLGDLPSDSPPDPQPPAASGPPSTVPLPHSSGIHGIALLSELADLAIQRQRS
Sbjct: 1261 DALVAATINLGDLPSDSPPDPQPPAASGPPSTVPLPHSSGIHGIALLSELADLAIQRQRS 1320
Query: 1321 ERTVPEEEEDVLAFNLQHLATLATAWSLVEAAGLDSSTAPAQPPTANPCSGPRLTPRMQI 1380
ERTVPEEEEDVLAFNLQHLATLATAWSLVEAAGLDSSTAPAQPPTANPCSGPRLTPRMQI
Sbjct: 1321 ERTVPEEEEDVLAFNLQHLATLATAWSLVEAAGLDSSTAPAQPPTANPCSGPRLTPRMQI 1380
Query: 1381 LQRKDTWTPKTKPVCPLKAAIDRLDTQEVGMRVRLAELQRRYKEKQRELARLQRKHDHER 1440
LQRKDTWTPKTKPVCPLKAAIDRLDTQEVGMRVRLAELQRRYKEKQRELARLQRKHDHER
Sbjct: 1381 LQRKDTWTPKTKPVCPLKAAIDRLDTQEVGMRVRLAELQRRYKEKQRELARLQRKHDHER 1440
Query: 1441 DESSRSPARRGPGRPRKRKHSSSLPAPRPTGPLPRSDGKKVKAVRTSLGLLCAELRGGSG 1500
DESSRSPARRGPGRPRKRKHSSSLPAPRPTGPLPRSDGKKVKAVRTSLGLLCAELRGGSG
Sbjct: 1441 DESSRSPARRGPGRPRKRKHSSSLPAPRPTGPLPRSDGKKVKAVRTSLGLLCAELRGGSG 1500
Query: 1501 GEPAKKRSKLERSVYAGLQTASVEKAQCKKSSCQGGLAPSVAHRVAQLKPKVKSKGLPTG 1560
GEPAKKRSKLERSVYAGLQTASVEKAQCKKSSCQGGLAPSVAHRVAQLKPKVKSKGLPTG
Sbjct: 1501 GEPAKKRSKLERSVYAGLQTASVEKAQCKKSSCQGGLAPSVAHRVAQLKPKVKSKGLPTG 1560
Query: 1561 LSSFQQKEATPGGRIREKLSRAKSAKVSGATRHPQPKGHGSRETPRCPAQPSVAASQEAG 1620
LSSFQQKEATPGGRIREKLSRAKSAKVSGATRHPQPKGHGSRETPRCPAQPSVAASQEAG
Sbjct: 1561 LSSFQQKEATPGGRIREKLSRAKSAKVSGATRHPQPKGHGSRETPRCPAQPSVAASQEAG 1620
Query: 1621 NGYDSEDCEGLLGTEAPPREAGLLLHTGASVAVLGPSPSSVVKMEANQKAKKKKERQGLL 1680
NGYDSEDCEGLLGTEAPPREAGLLLHTGASVAVLGPSPSSVVKMEANQKAKKKKERQGLL
Sbjct: 1621 NGYDSEDCEGLLGTEAPPREAGLLLHTGASVAVLGPSPSSVVKMEANQKAKKKKERQGLL 1680
Query: 1681 GACRLSSPESEVKIKRRSVKAKVGTTLERAPGQRPPGALGKKKAKGKAKGSLRAEPGATP 1740
GACRLSSPESEVKIKRRSVKAKVGTTLERAPGQRPPGALGKKKAKGKAKGSLRAEPGATP
Sbjct: 1681 GACRLSSPESEVKIKRRSVKAKVGTTLERAPGQRPPGALGKKKAKGKAKGSLRAEPGATP 1740
Query: 1741 SRDALFNPSRAFACREEGSQLASERLKRATRKGTVLQPVLRRKNGALSITLATRNAKAIL 1800
SRDALFNPSRAFACREEGSQLASERLKRATRKGTVLQPVLRRKNGALSITLATRNAKAIL
Sbjct: 1741 SRDALFNPSRAFACREEGSQLASERLKRATRKGTVLQPVLRRKNGALSITLATRNAKAIL 1800
Query: 1801 GKGRKLSKVKHKAGKQGKGRAVSRLLESFAVEEDFEFDDNSSFSEEEEDEEEEEEDSGPL 1860
GKGRKLSKVKHKAGKQGKGRAVSRLLESFAVEEDFEFDDNSSFSEEEEDEEEEEEDSGPL
Sbjct: 1801 GKGRKLSKVKHKAGKQGKGRAVSRLLESFAVEEDFEFDDNSSFSEEEEDEEEEEEDSGPL 1860
Query: 1861 SAEQSAALARSCAIHKEDLRDGLPVLIPKEDSLLYAGSVRTLQPPDIYSIVIEGERGNRQ 1920
SAEQSAALARSCAIHKEDLRDGLPVLIPKEDSLLYAGSVRTLQPPDIYSIVIEGERGNRQ
Sbjct: 1861 SAEQSAALARSCAIHKEDLRDGLPVLIPKEDSLLYAGSVRTLQPPDIYSIVIEGERGNRQ 1920
Query: 1921 RIYSLEQLLQEAVLDVRPQSSRYLPPGTRVCAYWSQKSRCLYPGNVVRGASGDEDEDLDS 1980
RIYSLEQLLQEAVLDVRPQSSRYLPPGTRVCAYWSQKSRCLYPGNVVRGASGDEDEDLDS
Sbjct: 1921 RIYSLEQLLQEAVLDVRPQSSRYLPPGTRVCAYWSQKSRCLYPGNVVRGASGDEDEDLDS 1980
Query: 1981 VVVEFDDGDTGHIAVSNVRLLPPDFKIQCTEPSPALLVSSSCRRTKKVSSEAPPPSEAAT 2040
VVVEFDDGDTGHIAVSNVRLLPPDFKIQCTEPSPALLVSSSCRRTKKVSSEAPPPSEAAT
Sbjct: 1981 VVVEFDDGDTGHIAVSNVRLLPPDFKIQCTEPSPALLVSSSCRRTKKVSSEAPPPSEAAT 2040
Query: 2041 PSLSPKAQDGPEALKTPGKKSISKDKAGKAELLTSGAKSPTGASDHFLGRRGSPLLSWSA 2100
PSLSPKAQDGPEALKTPGKKSISKDKAGKAELLTSGAKSPTGASDHFLGRRGSPLLSWSA
Sbjct: 2041 PSLSPKAQDGPEALKTPGKKSISKDKAGKAELLTSGAKSPTGASDHFLGRRGSPLLSWSA 2100
Query: 2101 VAQTKRKAVAAASKGPGVLQNLFQLNGSSKKLRAREALFPVHSVATPIFGNGFRADSFSS 2160
VAQTKRKAVAAASKGPGVLQNLFQLNGSSKKLRAREALFPVHSVATPIFGNGFRADSFSS
Sbjct: 2101 VAQTKRKAVAAASKGPGVLQNLFQLNGSSKKLRAREALFPVHSVATPIFGNGFRADSFSS 2160
Query: 2161 LASSYAPFVGGTGPGLPRGAHKLLRAKKAERVEAEKGGRRRAGGEFLVKLDHEGVTSPKN 2220
LASSYAPFVGGTGPGLPRGAHKLLRAKKAERVEAEKGGRRRAGGEFLVKLDHEGVTSPKN
Sbjct: 2161 LASSYAPFVGGTGPGLPRGAHKLLRAKKAERVEAEKGGRRRAGGEFLVKLDHEGVTSPKN 2220
Query: 2221 KTCKALLMGDKDFSPKLGRPLPSPSYVHPALVGKDKKGRAPIPPLPMGLALRKYAGQAEF 2280
KTCKALLMGDKDFSPKLGRPLPSPSYVHPALVGKDKKGRAPIPPLPMGLALRKYAGQAEF
Sbjct: 2221 KTCKALLMGDKDFSPKLGRPLPSPSYVHPALVGKDKKGRAPIPPLPMGLALRKYAGQAEF 2280
Query: 2281 PLPYDSDCHSSFSDEDEDGPGLAAGVPSRFLARLSVSSSSSGSSTSSSSGSVSTSSLCSS 2340
PLPYDSDCHSSFSDEDEDGPGLAAGVPSRFLARLSVSSSSSGSSTSSSSGSVSTSSLCSS
Sbjct: 2281 PLPYDSDCHSSFSDEDEDGPGLAAGVPSRFLARLSVSSSSSGSSTSSSSGSVSTSSLCSS 2340
Query: 2341 DNEDSSYSSDDEDPALLLQTCLTHPVPTLLAQPEALRSKGSGPHAHAQRCFLSRATVAGT 2400
DNEDSSYSSDDEDPALLLQTCLTHPVPTLLAQPEALRSKGSGPHAHAQRCFLSRATVAGT
Sbjct: 2341 DNEDSSYSSDDEDPALLLQTCLTHPVPTLLAQPEALRSKGSGPHAHAQRCFLSRATVAGT 2400
Query: 2401 GAGSGPSSSSKSKLKRKEALSFSKAKELSRRQRPPSVENRPKISAFLPARQLWKWSGNPT 2460
GAGSGPSSSSKSKLKRKEALSFSKAKELSRRQRPPSVENRPKISAFLPARQLWKWSGNPT
Sbjct: 2401 GAGSGPSSSSKSKLKRKEALSFSKAKELSRRQRPPSVENRPKISAFLPARQLWKWSGNPT 2460
Query: 2461 QRRGMKGKARKLFYKAIVRGEETLRVGDCAVFLSAGRPNLPYIGRIESMWESWGSNMVVK 2520
QRRGMKGKARKLFYKAIVRGEETLRVGDCAVFLSAGRPNLPYIGRIESMWESWGSNMVVK
Sbjct: 2461 QRRGMKGKARKLFYKAIVRGEETLRVGDCAVFLSAGRPNLPYIGRIESMWESWGSNMVVK 2520
Query: 2521 VKWFYHPEETKLGKRQCDGKNALYQSCHEDENDVQTISHKCQVVAREQYEQMARSRKCQD 2580
VKWFYHPEETKLGKRQCDGKNALYQSCHEDENDVQTISHKCQVVAREQYEQMARSRKCQD
Sbjct: 2521 VKWFYHPEETKLGKRQCDGKNALYQSCHEDENDVQTISHKCQVVAREQYEQMARSRKCQD 2580
Query: 2581 RQDLYYLAGTYDPTTGRLVTADGVPILC 2608
RQDLYYLAGTYDPTTGRLVTADGVPILC
Sbjct: 2581 RQDLYYLAGTYDPTTGRLVTADGVPILC 2608
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 590 bits (1521), Expect = e-168
Identities = 501/1394 (35%), Positives = 651/1394 (46%), Gaps = 245/1394 (17%)
Query: 1419 QRRYKEKQRELA-RLQRKHDHERDESSRSPARRGPGRPRKRKHSSSLPAPRPTGPLPRSD 1477
+++ Q +LA +L + + + +SP + K K S R P
Sbjct: 1616 KKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSDSAGGKSKTSGG--CGRYLTPYDSLL 1673
Query: 1478 GKKVKAVRTSLGLLCAELRGGSGGEPAKKRSKLERSVYAGLQTASVEKAQCKKSSCQGGL 1537
GK KA+ LGL R G AK R K+E A Q S + S
Sbjct: 1674 GKNRKALAKGLGLSLKSSREGKHKRAAKTR-KMEVGFKARGQPKSAHSPFASEVSSYSYN 1732
Query: 1538 APSVAHRVAQLKPKVKSKG------LPTGLSSFQQKEATPGGRIREKLSRAKSAKVSGAT 1591
S LK + ++G P+ L S K + G KL++ A A
Sbjct: 1733 TDSEEDEEF-LKDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGG--PKLTKRGLA----AP 1785
Query: 1592 RHPQPKGHGSRETPRC------PAQPSVAASQE------------------------AGN 1621
R +PK SR+ P C A+ S + S E +G
Sbjct: 1786 RTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGG 1845
Query: 1622 GYDSEDCEGLLGTEAPPREAGLLLHTGASVA---VLGPSPSSVVKMEANQKAKKKKERQG 1678
GY E L GLL AS +GPS SVV++EA QKA+KK+ERQ
Sbjct: 1846 GYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPS-LSVVQLEAKQKARKKEERQS 1904
Query: 1679 LLGA-CRLSSPESEVKIKRRS----VKAKVG------TTLERAPGQRPPGALGKKKAK-- 1725
LLG + ESEVK+++RS ++ K G + PG R P KAK
Sbjct: 1905 LLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLA 1964
Query: 1726 ---GKAKGSLRA------EPGATPSRDALFNPSRA------------------------- 1751
G+ LR E G S D L+ R+
Sbjct: 1965 VEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAPATKTS 2024
Query: 1752 -------FACREEGSQLASERLKRATRKGTVLQP---VLRRKNGALSITLATRNAKAILG 1801
+ R++ + + R +KG P + + AL +A ++
Sbjct: 2025 RCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTA 2084
Query: 1802 KGRKLSKVKHKAGKQ---GKGRAVSRLLESFAVEEDFEFDDNSSFSEEEEDEEEEEEDSG 1858
R +K K K K+ GKG AVS+L+ES A EEDFE + +SSFSE+E G
Sbjct: 2085 AKRSKAKAKGKEVKKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPR------G 2138
Query: 1859 PLSAEQSAALARSCAIHKEDLRDGLPVLIPKEDSLLYAGSVRTLQPPDIYSIVIEGERGN 1918
RSC I K++L+DGL VLIP +D LLYAG V+T+ PDIY +V+EGERGN
Sbjct: 2139 GAVERPLTPAPRSCIIDKDELKDGLRVLIPMDDKLLYAGHVQTVHSPDIYRVVVEGERGN 2198
Query: 1919 RQRIYSLEQLLQEAVLDVRPQSSRYLPPGTRVCAYWSQKSRCLYPGNVVRGASGDEDEDL 1978
R IY LEQLLQEA++DVRP S+R+LP GTR+ AYWSQ+ RCLYPG VVRG D ++D
Sbjct: 2199 RPHIYCLEQLLQEAIIDVRPASTRFLPQGTRIAAYWSQQYRCLYPGTVVRGLL-DLEDDG 2257
Query: 1979 DSVVVEFDDGDTGHIAVSNVRLLPPDFKIQCTEPSPALLVSSSCRRTKKVS--------- 2029
D + VEFDDGDTG I +S++RLLPPD+KIQC EPSPALLV S+ RR++K S
Sbjct: 2258 DLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEGKDG 2317
Query: 2030 ----SEAP---------PPSEAATPSLSPKAQDG---------PEALK---TPGKKSISK 2064
SE P PS A + ++G P AL+ TPG K
Sbjct: 2318 GTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPP 2377
Query: 2065 ---DKAGKAELLTSGAKSPTGASDHFLGRRG----------------SPLLSWSAVAQTK 2105
DK KA P+ A F +PL++ A
Sbjct: 2378 EPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKP 2437
Query: 2106 RKAVAAASKG------PGV-LQNLFQLNG----SSKKLRAREALFPVHSVATPIFGNGFR 2154
+KA AA G PG + L +L+ S K +A+EAL P G
Sbjct: 2438 KKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLRED---PGAGGWQE 2494
Query: 2155 ADSFSSLASSYAPFVGGTGPGLP--RGAHKLLRAKKAERVEAEKGGRRRAGGEFLVKLDH 2212
S SL S Y P G + P P + L + + E G ++ + + +
Sbjct: 2495 PKSLLSLGS-YPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDK--AQAEQ 2551
Query: 2213 EGVTSPKNKTCKALLMGDKDFSPKLGRPLPSPSYVHPALVGKDKKGRAPIPPLPMGLALR 2272
+G ++ + + S S S G DK G G
Sbjct: 2552 DGAEESESSSSSSSGSSSSSSSSS-----SSGSETEGEEEG-DKNGDGGCGT--GGRNCS 2603
Query: 2273 KYAGQAEFPLPYDSDCHSSFSDEDEDGPGLAAGVPSRFLARLSVSSSSSGSSTSSSSGSV 2332
+ +A P S SS S ++ S + S SSSSS SS+SSSS S
Sbjct: 2604 AASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2663
Query: 2333 STSSLCSSD-NEDSSYSSDDED-PALLLQTCLTHPVPTLLAQPEALRSKGSG-PHAHAQR 2389
S+SS SS +EDSS SSDDE PA +PT +A + G P AH+
Sbjct: 2664 SSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPT-----KATKQAGKARPSAHSP- 2717
Query: 2390 CFLSRATVAGTGAGSGPS----------SSSKSKLKRKEALSFSKAKELSRRQRPPSVEN 2439
+ T A P + +KS+ K++E + KEL++RQR PSVEN
Sbjct: 2718 ---GKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVEN 2774
Query: 2440 RPKISAFLPARQLWKWSGNPTQRRGMKGKARKLFYKAIVRGEETLRVGDCAVFLSAGRPN 2499
RPKI+AFLPARQLWKW G PTQRRGMKGKARKLFYKAIVRG+E +R+GDCAVFLSAGRPN
Sbjct: 2775 RPKIAAFLPARQLWKWFGKPTQRRGMKGKARKLFYKAIVRGKEMIRIGDCAVFLSAGRPN 2834
Query: 2500 LPYIGRIESMWESWGSNMVVKVKWFYHPEETKLGKRQCDGKN------------------ 2541
LPYIGRI+SMWESWG+NMVV+VKWFYHPEET GK+ G++
Sbjct: 2835 LPYIGRIQSMWESWGNNMVVRVKWFYHPEETSPGKQFHQGQHWDQKSSRSLPAALRVSSQ 2894
Query: 2542 -------ALYQSCHEDENDVQTISHKCQVVAREQYEQMARSRKCQDRQDLYYLAGTYDPT 2594
ALYQS H DENDVQT+SHKC VV EQYEQM +++K QD + LYYLAGTY+PT
Sbjct: 2895 RKDFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLKTKKYQDSEGLYYLAGTYEPT 2954
Query: 2595 TGRLVTADGVPILC 2608
TG + + DGVP+LC
Sbjct: 2955 TGMIFSTDGVPVLC 2968
Score = 401 bits (1030), Expect = e-111
Identities = 511/1814 (28%), Positives = 740/1814 (40%), Gaps = 359/1814 (19%)
Query: 1 MDGRDFAP-------PPHLLSERGSLGHR-SAAAAARLAPAGPAAQPPAHFQPGKYFPSP 52
MDGRDF P PP LLS HR AA A RL PA+ P PGKY
Sbjct: 1 MDGRDFGPQRSVHGPPPPLLSGLAMDSHRVGAATAGRL----PASGLPGPLPPGKYMAG- 55
Query: 53 LPMASHTASSRLMGSSPASSFMGSFLTSSLGSAASTHPSGPSSSPPEQAYRGSHPTTS-- 110
L + H P +F+GSF+ S +G +AS+H S P P + ++R P+
Sbjct: 56 LNLHPH----------PGEAFLGSFVASGMGPSASSHGS-PVPLPSDLSFRSPTPSNLPM 104
Query: 111 -QIWFSHSHEAPGYPRFSGSLASTFLPVSHLDHHGNSNVLY---GQHRFYGTQK------ 160
Q+W +H+HE G+ L ++L ++HL+ + + L GQ + TQK
Sbjct: 105 VQLWAAHAHE--GFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGG 162
Query: 161 DNFYLRNLPPQPTLLPANHNFPSVARAAPAHPMGSCSRDRDRGEAGSLQKGPKDFDRFLV 220
D FYL +L + + PS H G+ ++ S + GP
Sbjct: 163 DGFYLPTAGAPGSL---HSHAPSARTPGGGHSSGAPAK------GSSSRDGP-------- 205
Query: 221 GKELGREKAGKAAE-----GKERPAAE-EDGGKERHKLVLPVPADGHCREGGPAPRGACE 274
+E+AG+ E GK+ P A E+ R + L A R+ PR A
Sbjct: 206 ----AKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLA-- 259
Query: 275 GRPKHLTSCLLNTKVLNGEMGRAALASCAGGM--LGRPGTGVVTSGRCAKEAAGPPEPGP 332
+ L+ L +K N + + L C GG +G P AKEAA E
Sbjct: 260 ---ERLSPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEG-- 314
Query: 333 AFSECLERRQMLHHTASYAGPPPPLSTAAGSFPCLQLHGGPDGLCPLQDKAPRDLKASGP 392
+ L R + L P P A P P G+ + + R+ + P
Sbjct: 315 --ARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAP 372
Query: 393 TFVPSVGHLADKGRPFQAAEACAVAGEGKDRHLEGTMAPDHAAPYGVSYAHLKAEGKGER 452
TFVPSV ++ P Q A A + + R E AP G + EG E+
Sbjct: 373 TFVPSVEAFDERPGPIQIASQ---ARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREK 429
Query: 453 --------RPGGFEAALNPRLKGLDYLSSAGPEASFPGLPKSGLDKSGYFELPTSSQDCA 504
RP +A P ++ + A P+ P++ + + + C
Sbjct: 430 NSVIRSLKRPPPADA---PTVRA----TRASPD------PRAYVPAKELLKPEADPRPCE 476
Query: 505 RPGHQDPLGGKAPQACCTLDKTVGKEAPAGPP-----------GAQKVARIRHQQHLMAA 553
R + P G A QA G+ P GP A ++A + Q H A
Sbjct: 477 R-APRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHHSRA 535
Query: 554 EVEQGGIGAEAKRKSLELASLGYSGPHLPPWGVQAGQGTAMAISEERKAGAYLDPFGSGL 613
E E + A + +K+ G LP G+ A + + A+ GSG
Sbjct: 536 EEEAAVVAASSSKKAYL-----DPGAVLPRSAATCGRPVA-----DMHSAAH----GSG- 580
Query: 614 QQAALLPQELPAPPDEVSAMKNLLKYSSQ----ALVV-----GQKAPLVGLGGLK----- 659
E SAM++L+KYS A+ V G+K+P GLG +K
Sbjct: 581 ---------------EASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPEPAP 625
Query: 660 --ASCIQQEAKFLSSKGPGQS---------ERPDCARS--REHDTTHGDGEVRQPPVGIA 706
A + +A+ S GP ERP+ A++ RE G+ EVR PPVGIA
Sbjct: 626 TSAGASRAQARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIA 685
Query: 707 VALARQKDTVSRSEAAYGTNTARQGRAAPAFKGGGGPRSTHALDLEAEEERTRLCDDRLG 766
VA+ARQKD+ G + + KG G +D A RL RL
Sbjct: 686 VAVARQKDSGGSGRLGPGLVDQERSLSLSNVKGHGRA-DEDCVDDRARHREERLLGARLD 744
Query: 767 LASRELLLQDSKDRVEFARIHPPSSCPGDLAPHLMMQ-------SGQLGGDPAPHTHPHP 819
+E LL++SK+ + AR+HP S P L P+LM+ SG+ DPA H HP
Sbjct: 745 -RDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPALAGSGRWSADPAAHLATHP 803
Query: 820 PWLPRTRSPSLWMGGHSYGLGHPALHQNLPPGFPASVAGPVPSVFPLPQDAPT-QLVILP 878
WLPR+ + S+W+ GH YGLG P+LHQ + P FP + G +PS + +D + QLV++P
Sbjct: 804 -WLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIP 862
Query: 879 SEPTPHSAPHALADVMDQAS---LWPPMY-GGRGPASHMQHPGQLPVYSRPQLLRQQELY 934
S+ PH A++M++A+ LWP +Y GR P H Q QL ++S+ LRQQE
Sbjct: 863 SDHLPH-----FAELMERATVPPLWPALYPPGRSPLHHAQ---QLQLFSQQHFLRQQEFL 914
Query: 935 ALQQQ--RAAQFQR---------KPEDQHLDLEE-------PAQEKAPKSTHKPVALTPT 976
LQQQ +A + QR K ++ ++EE A KA +T P L
Sbjct: 915 YLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRK 974
Query: 977 APG---------------APSPAAGPT---------KLPPCCHPPD---PKPPASSPTPP 1009
PG PSP A P KL PP P P+S PT P
Sbjct: 975 PPGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSP 1034
Query: 1010 PRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGL-- 1067
P S P T + P + V + + + S + S D+PP Y P L
Sbjct: 1035 PPASPPPTPGI-TRKEEAPENVVEKKDLELEKEAPSPFQALFS--DIPPRY--PFQALPP 1089
Query: 1068 --GFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPP--CSPRSLEEPGLLSGA 1123
G P + + D + + P P R L E P SP + EP L G
Sbjct: 1090 HYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEP-LREGP 1148
Query: 1124 RE---ATQDLAATPYPTERGPQ--GKAADPSPLEGLQELQC--------AALLEAGGPEA 1170
E A +++ A + GP P PL + + LLEA A
Sbjct: 1149 EEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSA 1208
Query: 1171 TGQAHSTQG------GAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQP---- 1220
TGQ+ + E R G P + A ++ +P L + E+P
Sbjct: 1209 TGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQL---TPETLVEAKEEPVEVP 1265
Query: 1221 --APEEDELEEDELGQQSMEDSE-----EDCG-----GAPDNSHPPRALPGLDALVAATI 1268
P + + E+ L Q + +S+ DC G + P A+P ++ +T
Sbjct: 1266 VAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVP----VLGSTC 1321
Query: 1269 NLGDLPSD----SPPDPQP-----PAASGPPSTVPLP---------------------HS 1298
L + SD S DP AA+ P PLP
Sbjct: 1322 FLEEASSDQFLPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALEKLEAAESLVLEQ 1381
Query: 1299 SGIHGIALLSELADLAIQRQRSERTVPEEEEDVLAFNLQHLATLATAWSLVEAAGLDSST 1358
S +HGI LLSE+A+L ++R RS+ E V +L+ L AAG
Sbjct: 1382 SFLHGITLLSEIAELELER-RSQEMGGAERALVARPSLESLL----------AAGSHMLR 1430
Query: 1359 APAQPPTANPCSGPRLTPRMQILQRKDTW-TPKTKPVCPLKAAIDRLDTQEVGMRVRLAE 1417
P +P RL PR +K +W K + + +K++++ +D E+ R+RLAE
Sbjct: 1431 EVLDGPVVDPLKNLRL-PRELKPNKKYSWMRKKEERMYAMKSSLEDMDALELDFRMRLAE 1489
Query: 1418 LQRRYKEKQRELARLQRKHDHE--RDESSRSPARRGPGRPRKRKHS-SSLPAPRPTGPLP 1474
+QR+YKEKQREL +LQR+ D E R+E RS ARRGPGRPRKR H+ S+L PR G
Sbjct: 1490 VQRQYKEKQRELVKLQRRRDSEDRREEPHRSLARRGPGRPRKRTHAPSALSPPRKRGKSG 1549
Query: 1475 RSDGK-KVKAVRTSLGLLCAELRGGSGGEPAKKRSKLERSVYAGLQTASVEKAQCKKSSC 1533
S GK K++ TS + G+G K S+ E G+ KA+ + +
Sbjct: 1550 HSSGKLSSKSLLTS-----DDYELGAGIRKRHKGSEEEHDALIGM-----GKARGRNQTW 1599
Query: 1534 QGGLAPSVAHRVAQLKPKVKSKGLPTGLSSFQQKEATPGGRIREKLSRAKSAKVSGATRH 1593
A S ++QLK K K ++S Q++ A+ ++ + LS K K+ +
Sbjct: 1600 DEHEASS--DFISQLKIKKKK------MASDQEQLAS---KLDKALSLTKQDKLKSPFKF 1648
Query: 1594 PQPKGHGSRETPRC 1607
G S+ + C
Sbjct: 1649 SDSAGGKSKTSGGC 1662
Score = 59.3 bits (142), Expect = 5e-08
Identities = 120/508 (23%), Positives = 179/508 (35%), Gaps = 94/508 (18%)
Query: 946 RKPE-----DQHLDLEEPAQEKAPKSTHKPVALTPTA-PGA----PSPAAGPTKLP---P 992
RKP D+ LEE ST P+AL P++ PG+ P P K P P
Sbjct: 2334 RKPSAKAKGDRAATLEEGNPTDEVPST--PLALEPSSTPGSKKSPPEPVDKRAKAPKARP 2391
Query: 993 CCHPPDPKPPASSPTPPPRPSA----------PCTLNVCPASSPGPGSRVRSAEEKNGEG 1042
P P PPA + P P P A P L PA+ P P + R+AEE +G
Sbjct: 2392 APPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKP-KKARAAEESGAKG 2450
Query: 1043 QQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNL----EDPETMQTTAPGAQPEPT 1098
+ + E +L L + G + P + EDP G EP
Sbjct: 2451 PRRPGE----EAEL----LVKLDHEGVTSPKSKKAKEALLLREDP------GAGGWQEPK 2496
Query: 1099 RTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERGPQGK-AADPSPLEGLQEL 1157
G PP + S EP P+P + G A +P P GL
Sbjct: 2497 SLLSLGSYPPAAGSS--EP--------------KAPWP--KATDGDLAQEPGP--GL--- 2533
Query: 1158 QCAALLEAGGPEATGQAHSTQGGAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEG 1217
++G P++ +A + Q GA E S G SS +SS S E EG
Sbjct: 2534 ---TFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSS-------SSSSGSETEG 2583
Query: 1218 EQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDS 1277
E+ E D+ G +C A + P + + +++ + S S
Sbjct: 2584 EE--------EGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSS 2635
Query: 1278 PPDPQPPAASGPPSTVPLPHSSGIHGIALLSELADLAIQRQRSERTVPEEEEDVLAFNLQ 1337
++S S+ SS + S + + + + ++E A
Sbjct: 2636 SSSSSSSSSSSSSSS---SSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAG 2692
Query: 1338 HLATLATAWSLVEAAGLDSSTAPAQPPTANPCSGPRLTPRM--QILQRKDTWTPKTKPVC 1395
A A + AG +A + P P P+ P Q LQ K K++P
Sbjct: 2693 PSAQAALPTKATKQAGKARPSAHS-PGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRP-- 2749
Query: 1396 PLKAAIDRLDTQEVGMRVRLAELQRRYK 1423
+ + T+E+ R RL ++ R K
Sbjct: 2750 KKREGVHLPTTKELAKRQRLPSVENRPK 2777
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 76.6 bits (187), Expect = 3e-13
Identities = 101/414 (24%), Positives = 134/414 (32%), Gaps = 90/414 (21%)
Query: 970 PVALTPTAPGAPSPAAGPTKLPPCCHPPDPKP-----------------PASSPTPPPRP 1012
P TP AP P A P + PP HPP P P P++ P P RP
Sbjct: 643 PTCPTP-APVPPPEAPSPFRAPPF-HPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARP 700
Query: 1013 SAPCTLNVCPASSPGPGS---RVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGF 1069
P T N S PG S R+ E + G S D I + PP + P G
Sbjct: 701 GPPTTANHLGLSVPGLVSVPPRLLPGPENHRAG--SNEDPILAPSGTPPPTIPPDETFGG 758
Query: 1070 SLP------------SDVHSSNLEDPETMQTTAP-GAQPEPTRTFLPGEPPPCSPRSLEE 1116
+P SDV S D + P G P P PPP +P
Sbjct: 759 RVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPT 818
Query: 1117 PGLLSGAREATQDLAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATG---- 1172
A+E ++L A P P P P P+ G L L+ G P G
Sbjct: 819 ASPPVPAKEEPEELPAAPGPLPPPPP----PPPPVPGPVTLPPPQLVPEGTPGGGGPPAL 874
Query: 1173 ---------------------QAHSTQGGAREERSREEGEQGPSSGASSQVLEQRAGSPG 1211
+ + EE EE E+ + E+
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEE 934
Query: 1212 ALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDALVAATINLG 1271
E+EGE EE+E EE+E + +ED E G G
Sbjct: 935 FEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAG------------------------G 970
Query: 1272 DLPSDSPPDPQPPAASGPPSTVPLPHSSGIHGIALLSELADLAIQRQRSERTVP 1325
++ +PP P P A PP + P LL E+ + + +R T P
Sbjct: 971 EVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAP 1024
Score = 63.2 bits (152), Expect = 3e-09
Identities = 121/534 (22%), Positives = 174/534 (32%), Gaps = 140/534 (26%)
Query: 811 PAPHTHPHPPWLPRTRSPSLWMGGHSYGLGHPALHQNLPPGFPASVAGPVPSVFPLPQDA 870
P T P P +P +PS + + G ++P P AGP+PS P+P
Sbjct: 640 PMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSAR 699
Query: 871 PTQLVILPSEPTPHSAPHALADVMDQASLWPPMYGGRGPASHMQHPGQLPVYSR----PQ 926
P P +A H V S+ P + G P +H + P+ + P
Sbjct: 700 PGP---------PTTANHLGLSVPGLVSVPPRLLPG--PENHRAGSNEDPILAPSGTPPP 748
Query: 927 LLRQQELYALQQQRAAQFQRKPE---DQHLDLEEPAQEKA-------------PKSTHKP 970
+ E + + R A E D + LE + + P S P
Sbjct: 749 TIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATP 808
Query: 971 VALTPTAPGAPSPA-----------AGPTKLPPCCHPPDPKPPASSPT--PPPR------ 1011
+ PT P SP A P LPP PP P PP P PPP+
Sbjct: 809 PPIAPTGPPTASPPVPAKEEPEELPAAPGPLPP---PPPPPPPVPGPVTLPPPQLVPEGT 865
Query: 1012 ------PSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMA 1065
P+ L V +S EE+ E ++ + E + Y
Sbjct: 866 PGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEE 925
Query: 1066 GLGFSLPSDV-----------------HSSNLEDPETMQTTAPGAQPE----PTRTFLPG 1104
+ LE+ E ++ G + E P T P
Sbjct: 926 EEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPA 985
Query: 1105 EPPPCSPRSLE-----EPGLLSGAREATQDLAATPYPTERGPQGKAADPSPLEGLQELQC 1159
PPP SP ++ EPGLL E + ERG AD +P L
Sbjct: 986 LPPPESPPKVQPEPEPEPGLLLEVEEPGTE-------EERG-----ADTAP-----TLAP 1028
Query: 1160 AALLEAGGPEATGQAHSTQGGAREERSREEGEQGPSSGASSQVL--EQRAGSPGALEDEG 1217
AL G E G++ P++G Q L E+ + P LE+E
Sbjct: 1029 EALPSQGEVEREGES-------------------PAAGPPPQELVEEEPSAPPTLLEEET 1069
Query: 1218 E------QPAPE---EDELEEDELGQQSMEDSEEDCGG--------APDNSHPP 1254
E QP PE E+E+E + + E ++D PD+ PP
Sbjct: 1070 EDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPP 1123
Score = 38.1 bits (87), Expect = 0.11
Identities = 81/334 (24%), Positives = 103/334 (30%), Gaps = 73/334 (21%)
Query: 1002 PASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYL 1061
P P P P+ P V P +P P + P PPG
Sbjct: 633 PRVPPLQPMGPTCPTPAPVPPPEAPSP---------------------FRAPPFHPPG-- 669
Query: 1062 RPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLS 1121
PM +G S+PS P P A P P+ PG P + L PGL+S
Sbjct: 670 -PMPSVG-SMPS-------AGPMPSAGPMPSAGPVPSAR--PGPPTTANHLGLSVPGLVS 718
Query: 1122 GAREATQDLAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGA 1181
P GP+ A + + L +G P T T GG
Sbjct: 719 -----------VPPRLLPGPENHRAGSN--------EDPILAPSGTPPPTIPPDETFGGR 759
Query: 1182 REERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSE 1241
+ ++ +S LE + + EG P P
Sbjct: 760 VPRPAFVHYDKEEASDVEIS-LESDSDDSVVIVPEGLPPLPPPPP--------SGATPPP 810
Query: 1242 EDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAASGP-----PSTVPLP 1296
G P S P A + L AA G LP PP P PP GP P VP
Sbjct: 811 IAPTGPPTASPPVPAKEEPEELPAAP---GPLP---PPPPPPPPVPGPVTLPPPQLVPEG 864
Query: 1297 HSSGIHGIALLSELADLAIQRQRSERTVPEEEED 1330
G AL +L + I E EEEE+
Sbjct: 865 TPGGGGPPALEEDLTVININSSDEEEEEEEEEEE 898
Score = 32.7 bits (73), Expect = 4.8
Identities = 19/40 (47%), Positives = 24/40 (60%), Gaps = 7/40 (17%)
Query: 1832 EEDFEFD--DNSSFSEEEEDEEEE-----EEDSGPLSAEQ 1864
EEDFE + D + EEEE+EEEE EE+ G L E+
Sbjct: 907 EEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946
Score = 32.0 bits (71), Expect = 8.2
Identities = 15/27 (55%), Positives = 20/27 (74%)
Query: 1830 AVEEDFEFDDNSSFSEEEEDEEEEEED 1856
A+EED + +S EEEE+EEEEEE+
Sbjct: 873 ALEEDLTVININSSDEEEEEEEEEEEE 899
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 74.7 bits (182), Expect = 1e-12
Identities = 130/508 (25%), Positives = 172/508 (33%), Gaps = 82/508 (16%)
Query: 675 PGQSERPDCARSREHDTTHGDGEVRQPPVGIAVALARQKDTVSRSEAAYGTNTARQGRAA 734
P + R + + EH TT R+ P L R S A ++ AR G +A
Sbjct: 201 PTEGPRKSVSSASEHSTTEPSPAARRRP-SAGGGLQRPASRSLSSSATPLSSPARSGPSA 259
Query: 735 ------PAFKGGGGPRSTHALDLEAEEERTRLCDDRLGLASRELLLQDSKDRVEFARIHP 788
PA P+ AL + LG S L S ++ P
Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPP 319
Query: 789 P-------SSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTR------SPSLWMGGH 835
SS LA L + P+ T P PP P ++ SP+L H
Sbjct: 320 TLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL-QATH 378
Query: 836 SYGLGHPALHQ--NLPPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADV 893
S+ L P L PP P ++A P P P +P + P AP+ALA
Sbjct: 379 SF-LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP---QAPNALAVH 434
Query: 894 MDQASLWPPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHL 953
+ QA PP P+ +Q P P S P P
Sbjct: 435 LLQAPFSPP------PSPPVQAPFSPPA-SPPV--------------------SPS---- 463
Query: 954 DLEEPAQEKAPKSTHKPVALTPTAPGAP--SPAAGPTKLPPCCHPPDPKPPASSPTPPPR 1011
P + P P+ + P+ P +P SP+A P PP PP PP PPP+
Sbjct: 464 --ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP---PPQAPPPLAAPPLQLAKPPPQ 518
Query: 1012 PSAPCTLNVCPASS-PGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFS 1070
AP L P + P P + + + + T P PP P+ +
Sbjct: 519 --APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP-- 574
Query: 1071 LPSDVHSSNLEDPETMQTTAPGAQ---PEPTRTFLPGEPPPCSPRSLEEPGLLSGAREAT 1127
PS S L+ P T P P T PG PP P S LSG A
Sbjct: 575 -PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP---PPSRSPSSTLSGPDLAG 630
Query: 1128 QDLAATPYPTE-----RGPQGKAADPSP 1150
+AT P E GP+G AA P
Sbjct: 631 HSSSATSTPEELRGYDSGPEGGAAASPP 658
Score = 55.5 bits (132), Expect = 7e-07
Identities = 102/445 (22%), Positives = 145/445 (32%), Gaps = 77/445 (17%)
Query: 880 EPTPHSAPHALADVMDQASLWPPMYGGRG----PASH-----MQHPGQLPVYSRPQLLRQ 930
E P + P A + P GRG PA + + PG+ +RP L Q
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131
Query: 931 QELYALQQQRAAQFQRKPEDQHLDLEEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKL 990
+ L ++ A+ + + L A+ T PG PSPA
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT----------PGTPSPAMARRSR 181
Query: 991 PPCCHPPDPKP-PASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADI 1049
P+P P++ P PP + GP V SA E +
Sbjct: 182 AAGTEVGLPRPAPSARPRPP---------------TEGPRKSVSSASEHS---------- 216
Query: 1050 ITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDP-ETMQTTAPGAQPEPTRTFLPGEPPP 1108
T+EP P RP AG G P+ S+ P + + P A+ P P +P P
Sbjct: 217 -TTEPS-PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274
Query: 1109 CSPRSLEEPGLLSGAREATQDLAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGP 1168
++L P + ++A L P P A PSP AAL P
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALG----PLSSSP---LATPSP--------SAALQSQAPP 319
Query: 1169 EATGQAHSTQGGAREERSREEGEQGPSSGASSQVLEQ-----------RAGSPGALEDEG 1217
HS+ + PS+ S Q L GSP
Sbjct: 320 TLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS 379
Query: 1218 EQPAPEEDELEEDE-LGQQSMEDSEEDCGGAPDNSHP--PRALPGLDALVAATINLGDLP 1274
P+P L ++ +P S P P A P A A ++L P
Sbjct: 380 FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 439
Query: 1275 SDSPPDPQPPAASGPPSTVPLPHSS 1299
PP P A PP++ P+ S+
Sbjct: 440 FSPPPSPPVQAPFSPPASPPVSPSA 464
Score = 45.8 bits (107), Expect = 5e-04
Identities = 101/442 (22%), Positives = 131/442 (29%), Gaps = 69/442 (15%)
Query: 970 PVALTPTAPGAPSP-------------AAGPTKLPPCCHPPDPKPPASSPTPPPRPSAPC 1016
P LTP PG+P P AAG P A+ P PR
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG--- 78
Query: 1017 TLNVCPASSPGPGSR-VRSAEEKNGEGQ-----QSTADIITSEPDLPPGYLRP----MAG 1066
P S G SR S +G G+ ++T+ S P G RP G
Sbjct: 79 -----PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133
Query: 1067 LGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREA 1126
L S V + + GA+ + T PG P P R G G
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRD-TSGPTPGTPSPAMARRSRAAGTEVGLPRP 192
Query: 1127 TQDLAATPYPTERGP--------QGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQ 1178
+A P P GP + +PSP + L + A
Sbjct: 193 AP--SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250
Query: 1179 GGAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSME 1238
AR S + P+ + + +A P + + AP L L S
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS-- 308
Query: 1239 DSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAASGPPSTVPLPHS 1298
A S P LP + T L +P PP+ S PPS LP
Sbjct: 309 ------PSAALQSQAPPTLPATPHSSSLTCQLA-----TPLPLAPPSPSAPPSLQTLPSP 357
Query: 1299 SGIHGIALLSELADLAIQRQRSERTVPEEEEDVLAFNLQHLATLAT-AWSLVEAAGLDSS 1357
+ L +Q S P L+ LAT A L
Sbjct: 358 PATPPSQATTSLGSPTLQATHSFLPSPP------------LSPLATPPPQAPPALALPPL 405
Query: 1358 TAPAQPPTANPCSGPRLTPRMQ 1379
AP PP + P S P TP Q
Sbjct: 406 QAPPSPPASPPLS-PLATPSPQ 426
Score = 45.4 bits (106), Expect = 7e-04
Identities = 93/346 (26%), Positives = 114/346 (32%), Gaps = 54/346 (15%)
Query: 985 AGPTKLPPCCHPPD---PKPPASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGE 1041
AG P P P+PP S P PPP P P L V A+ G R AE G
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGS-PRPPP-PVTPAALRVLGAA--GAVGRKPLAERAGGI 65
Query: 1042 GQQSTADIITSEPDLPPGYLRPMAGLGFSLPSD--VHSSNLEDPETMQTTAPGAQPEPTR 1099
G A I S P P AG P+ S E + T+PG P R
Sbjct: 66 GG---ATIPESAPRAGP---TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR 119
Query: 1100 TFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTER----GPQGKAADPSP---LE 1152
P P L + GL A E AT P G + + P+P
Sbjct: 120 ASGTTRPGP-----LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 174
Query: 1153 GLQELQCAALLEAGGPEATGQAHS---TQGGAREERSREEGEQGPSSGASSQVLEQRAGS 1209
+ AA E G P A T+G + S E S+ S +R +
Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH----STTEPSPAARRRPSA 230
Query: 1210 PGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDN-SHPPRALP-GLDALVAAT 1267
G L+ P L S S G P +HP + P GL AL
Sbjct: 231 GGGLQ------RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284
Query: 1268 IN---------LGDLPSDSPPDPQPPAA---SGPPSTVPLPHSSGI 1301
+ LG L S P P AA PP+ PHSS +
Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSL 330
Score = 43.9 bits (102), Expect = 0.002
Identities = 84/330 (25%), Positives = 117/330 (35%), Gaps = 42/330 (12%)
Query: 1437 DHERDES-----SRSPARRGPGRPRKRKHSSSLPAPRPTGPLPRSDGKKVKAVRTSLGLL 1491
D++RD++ +R+PA R PG R S P P T R G R L
Sbjct: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPL--- 58
Query: 1492 CAELRGGSGGEPAKKRSKLERSVYAGLQTASVEKAQCKKSSCQGGLAPSVAHRVAQLKPK 1551
AE GG GG + S T+S A +S +G AP +
Sbjct: 59 -AERAGGIGGATIPE-SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG---P 113
Query: 1552 VKSKGLPTGLSS----------FQQKEATPGGRIREKLSRAKSAKVSGATRHPQPKGHGS 1601
V S G +G + +E G+ E R SA +GA R S
Sbjct: 114 VSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKR--SALSAGARRDT------S 165
Query: 1602 RETPRCP----AQPSVAASQEAGNGYDSEDCEGLLGTEAPPREAGLLLHTGASVAVLGPS 1657
TP P A+ S AA E G + TE P + + + + PS
Sbjct: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS----SASEHSTTEPS 221
Query: 1658 PSSVVKMEANQKAKKKKERQGLLGACRLSSPESEVKIKRRSVKAKVGTTLERAPGQ---R 1714
P++ + A ++ R A LSSP R + +A + + G R
Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281
Query: 1715 PPGALGKKKAKGKAKGSLRAEPGATPSRDA 1744
PP +K A G L + P ATPS A
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSA 311
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 73.2 bits (178), Expect = 3e-12
Identities = 129/501 (25%), Positives = 169/501 (33%), Gaps = 98/501 (19%)
Query: 675 PGQSERPDCARSREHDTTHGDGEVRQPPVGIAVALARQKDTVSRSEAAYGTNTARQGRAA 734
P + R + + EH TT R+ P L R S A ++ AR G +A
Sbjct: 192 PTEGPRKSVSSASEHSTTEPSPAARRRP-SAGGGLQRPASRSLSSSATPLSSPARSGPSA 250
Query: 735 ------PAFKGGGGPRSTHALDLEAEEERTRLCDDRLGLASRELLLQDSKDRVEFARIHP 788
PA P+ AL + LG S L S
Sbjct: 251 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS----------- 299
Query: 789 PSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTR------SPSLWMGGHSYGLGHP 842
PS+ P AP P+ T P PP P ++ SP+L HS+ L P
Sbjct: 300 PSAPPSPSAP------------PSLQTLPSPPATPPSQATTSLGSPTL-QATHSF-LPSP 345
Query: 843 ALHQ--NLPPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADVMDQASLW 900
L PP P ++A P P P +P + P AP+ALA + QA
Sbjct: 346 PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP---QAPNALAVHLLQAPFS 402
Query: 901 PPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLEEPAQ 960
PP P+ +Q P P S P P P
Sbjct: 403 PP------PSPPVQAPFSPPA-SPPV--------------------SPS------ATPPS 429
Query: 961 EKAPKSTHKPVALTPTAPGAP--SPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAPCTL 1018
+ P P+ + P+ P +P SP+A P PP PP PP PPP+ AP L
Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPSATP---PPQAPPPLAAPPLQLAKPPPQ--APPAL 484
Query: 1019 NVCPASS-PGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHS 1077
P + P P + + + + T P PP P+ + PS S
Sbjct: 485 ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP---PSPPAS 541
Query: 1078 SNLEDPETMQTTAPGAQ---PEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATP 1134
L+ P T P P T PG PP P S LSG A +AT
Sbjct: 542 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP---PPSRSPSSTLSGPDLAGHSSSATS 598
Query: 1135 YPTE-----RGPQGKAADPSP 1150
P E GP+G AA P
Sbjct: 599 TPEELRGYDSGPEGGAAASPP 619
Score = 48.5 bits (114), Expect = 8e-05
Identities = 98/431 (22%), Positives = 129/431 (29%), Gaps = 89/431 (20%)
Query: 985 AGPTKLPPCCHPPD---PKPPASSPTPPPRPSAPCTLNVC-------------------- 1021
AG P P P+PP S P PPP P P L V
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGS-PRPPP-PVTPAALRVLGAAGAVGRKPLAERAGGIGG 67
Query: 1022 ---PASSPGPGSRVRSAEEKNGEGQQS-----TADIITSEPDLPPGYLRP----MAGLGF 1069
P S+P G S +G G+++ T+ S P G RP GL
Sbjct: 68 ATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 127
Query: 1070 SLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQD 1129
S V + + GA+ + T PG P P R G G
Sbjct: 128 SAEETVARGKATEAPKRSALSAGARRD-TSGPTPGTPSPAMARRSRAAGTEVGLPRPAP- 185
Query: 1130 LAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREE 1189
+A P P GP+ + S + A + G GG + SR
Sbjct: 186 -SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG-----------GGLQRPASRSL 233
Query: 1190 GEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPD 1249
+ ++ G+P A QP P+ G Q++
Sbjct: 234 SSSATPLSSPARSGPSARGTPRA-PAHPSQPKPK---------GLQALR----------- 272
Query: 1250 NSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAASGPPSTVPLPHSSGIHGIALLSE 1309
PP+ P A L P +P PP+ S PPS LP +
Sbjct: 273 ---PPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329
Query: 1310 LADLAIQRQRSERTVPEEEEDVLAFNLQHLATLAT-AWSLVEAAGLDSSTAPAQPPTANP 1368
L +Q S P L+ LAT A L AP PP + P
Sbjct: 330 LGSPTLQATHSFLPSPP------------LSPLATPPPQAPPALALPPLQAPPSPPASPP 377
Query: 1369 CSGPRLTPRMQ 1379
S P TP Q
Sbjct: 378 LS-PLATPSPQ 387
Score = 47.4 bits (111), Expect = 2e-04
Identities = 86/328 (26%), Positives = 122/328 (37%), Gaps = 37/328 (11%)
Query: 1437 DHERDES-----SRSPARRGPGRPRKRKHSSSLPAPRPTGPLPRSDGKKVKAVRTSLGLL 1491
D++RD++ +R+PA R PG R S P P T R G R L
Sbjct: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPL--- 58
Query: 1492 CAELRGGSGGEPAKKRSKLERSVYAGLQTASV--EKAQCKKSSCQGGLA-PSVAHRVAQL 1548
AE GG GG + + AS E+A K++ G ++ P A +
Sbjct: 59 -AERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 117
Query: 1549 KPKVKSKGLPTGLSSFQQKEATPGGRIREKLSRAKSAKVSGATRHPQPKGHGSRETPRCP 1608
P + KGL +E G+ E R SA +GA R S TP P
Sbjct: 118 GP-LGQKGL-----RISAEETVARGKATEAPKR--SALSAGARRDT------SGPTPGTP 163
Query: 1609 ----AQPSVAASQEAGNGYDSEDCEGLLGTEAPPREAGLLLHTGASVAVLGPSPSSVVKM 1664
A+ S AA E G + TE P + + + + PSP++ +
Sbjct: 164 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS----SASEHSTTEPSPAARRRP 219
Query: 1665 EANQKAKKKKERQGLLGACRLSSPESEVKIKRRSVKAKVGTTLERAPGQ---RPPGALGK 1721
A ++ R A LSSP R + +A + + G RPP
Sbjct: 220 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP 279
Query: 1722 KKAKGKAKGSLRAEPGATPSRDALFNPS 1749
+K A G L + P ATPS A +PS
Sbjct: 280 RKDAAPALGPLSSSPLATPSPSAPPSPS 307
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 70.5 bits (171), Expect = 2e-11
Identities = 143/605 (23%), Positives = 205/605 (33%), Gaps = 94/605 (15%)
Query: 741 GGPRSTHALDLEAEEERTRLCDDR-LGLASRELLLQ-DSKDRVEFARIHPPSSCPGDLAP 798
G P+ H ++ +E C+ + LG A +L Q ++ E + PP P P
Sbjct: 394 GQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPP 453
Query: 799 HLMMQSGQLGGDPAPHTHPHPPWLPRTRSPSLWMGGHSYGLGHPALHQNLPPGFPASVAG 858
+S A P P LP + P + L P L P S
Sbjct: 454 E---ESPTSPPPEASRLSPPPEELPASPLPE------ALHLSRPLEESPLSPPPEESPLS 504
Query: 859 PVPSVFPL----------PQDAPTQLVI-LPSEPTPHSAPHALADVMDQASLWPPMYGGR 907
P P P P+++P + P P P ++P L+ +++ L PP
Sbjct: 505 PPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASP--LSPPFEESPLSPP----- 557
Query: 908 GPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLEEPAQEKAPKST 967
P +LP P+ R + PE+ + A P
Sbjct: 558 --------PEELPTSPPPEASRLSP-----PPEESPMSPPPEESPMSPPPEASRLFPPFE 604
Query: 968 HKPVALTPT-APGAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAPCTLNVCPASSP 1026
P++ P +P +P P A PP P P P S +PPP S L V SP
Sbjct: 605 ESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSP 664
Query: 1027 GP-GSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSD-VHSSNLED-- 1082
P S + E++ A ++ P+ P P P D + S LE+
Sbjct: 665 PPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESP 724
Query: 1083 ----PETMQ----TTAPGAQPEPTRTFLPGEP--PPCSPRSLEEPGLLSGAREATQDLAA 1132
PE Q + P P P L P P SP++ EEP L E L A
Sbjct: 725 LLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQA-EEPHLSPQPEEPC--LCA 781
Query: 1133 TPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGEQ 1192
P PQ + SP +EL + E + E + E+
Sbjct: 782 VPEEPHLSPQAEGPHLSPQP--EELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEE 839
Query: 1193 -----GPSSGASSQVLEQRAGSP---GALEDEGEQPAPEEDELEEDE--------LGQQS 1236
P S LE+ SP E+ G+ PAPEE L LG+ +
Sbjct: 840 PCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPA 899
Query: 1237 MEDSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPP------AASGPP 1290
+ + G P S P LP ++ + P PPDP PP A+ PP
Sbjct: 900 LSEP-----GEPPLSPLPEELP-----LSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPP 949
Query: 1291 STVPL 1295
+ PL
Sbjct: 950 ALSPL 954
Score = 50.4 bits (119), Expect = 2e-05
Identities = 129/554 (23%), Positives = 179/554 (32%), Gaps = 143/554 (25%)
Query: 780 RVEFARIHPPSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTRSPSLWMGGHSYGL 839
R E + + P P L+P + G PAP P P PSL S L
Sbjct: 845 RPEESHLSPELEKP-PLSPRPEKPPEEPGQCPAPE---ELPLFPPPGEPSL-----SPLL 895
Query: 840 GHPALHQNLPPGFPASVAGPVPSVFPL-PQDAPTQLVILPSEPTPHSAPHALADVMDQAS 898
G PAL + PG P P+P PL P P+ + P P P L+ ++ A+
Sbjct: 896 GEPALSE---PGEPP--LSPLPEELPLSPSGEPS---LSPQLMPPDPLPPPLSPIITAAA 947
Query: 899 LWPPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLEEP 958
PP P +++P S P+ AA P + P
Sbjct: 948 --PPALS---PLGELEYPFGAKGDSDPE-----------SPLAAPILETP------ISPP 985
Query: 959 AQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPAS-SPTPPPRPSAPCT 1017
+ P + P +PG+P A P + P PP P S P P + C+
Sbjct: 986 PEANCTDPEPVPPMILPPSPGSPVGPASPILMEPL--PPQCSPLLQHSLVPQNSPPSQCS 1043
Query: 1018 LNVCPASSPGPGSRVRSAEEKNGEGQQSTADII-TSEPDLPP-------GYLRPMAGLGF 1069
P S P P S + + E + + SEP+ P PM L
Sbjct: 1044 PPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSC 1103
Query: 1070 SLPS-----DVHSSNLEDPETMQ-TTAPGAQPEPTRT------FLPGEPPPCSPRSL--- 1114
PS D S ED + APG+QPEP +T L G P P L
Sbjct: 1104 PAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPV 1163
Query: 1115 ----------------------EEP-------------------------GLLSGAREAT 1127
EEP G S + +
Sbjct: 1164 TPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGS 1223
Query: 1128 QDLAATPYPTERGPQ----GKAADPSPL----------EGLQELQCAALLEAGGPEATGQ 1173
+ L +P P G G + D SP + L E + L +AG + G+
Sbjct: 1224 EPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGK 1283
Query: 1174 AHSTQGGAREERSREEGEQGPSS----------------GASSQVLEQRAGSPGALEDEG 1217
A +G R +R +QG SS G L+ A S L
Sbjct: 1284 AEGEKGRRRSSPARSRIKQGRSSSFPGRRRPRGGAHGGRGRGRARLKSTASSIETLVVAD 1343
Query: 1218 EQPAPEEDELEEDE 1231
+P ++E EED+
Sbjct: 1344 IDSSPSKEEEEEDD 1357
Score = 48.5 bits (114), Expect = 8e-05
Identities = 124/537 (23%), Positives = 181/537 (33%), Gaps = 112/537 (20%)
Query: 849 PPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADVMDQASLWPPMYGGRG 908
P P S + P P+D+PT P E +P S P D P
Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTSP---PPEDSPASPPPE-----DSLMSLP------- 719
Query: 909 PASHMQHPGQLPVYSRPQLL-RQQELYALQQQRAAQFQRKPEDQHLDLEEPAQEKAPKST 967
++ LP+ PQL R + + + +PE+ HL + +P+
Sbjct: 720 ----LEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPE 775
Query: 968 HKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAPCTLNVCPASSPG 1027
+ P P A GP L P P P P P PC SP
Sbjct: 776 EPCLCAVPEEPHLSPQAEGP-HLSPQPEELHLSPQTEEPHLSPVPEEPCL-------SPQ 827
Query: 1028 PGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDP--ET 1085
P E++ QS ++ P+ +L P L S E P E
Sbjct: 828 P--------EESHLSPQSEEPCLSPRPE--ESHLSP------ELEKPPLSPRPEKPPEEP 871
Query: 1086 MQTTAPGAQP------EPTRTFLPGEP-------PPCSPRSLEEPGLLSGAREATQDLAA 1132
Q AP P EP+ + L GEP PP SP E P SG + L
Sbjct: 872 GQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMP 931
Query: 1133 T-PYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGE 1191
P P P AA P L L EL+ GA+ G+
Sbjct: 932 PDPLPPPLSPIITAAAPPALSPLGELEYPF------------------GAK-------GD 966
Query: 1192 QGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNS 1251
P S ++ +LE P PE + + + + + S G+P
Sbjct: 967 SDPESPLAAPILETPISPP-----------PEANCTDPEPVPPMILPPSP----GSPVGP 1011
Query: 1252 HPPRALPGLDALVAATINLGDLPSDSPPDP-QPPAASGPPSTVPLPHS--SGIHGIALLS 1308
P + L + + +P +SPP PPA P +VP P S + G++ +
Sbjct: 1012 ASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPAL---PLSVPSPLSPIGKVVGVSDEA 1068
Query: 1309 ELADLAIQRQRSERTVPEEEEDVLAFNLQHLATL-----ATAWSLVEAAGLDSSTAP 1360
EL ++ ++ SE P E + + L + A +L + +GL TAP
Sbjct: 1069 ELHEMETEKV-SEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAP 1124
Score = 46.2 bits (108), Expect = 4e-04
Identities = 98/392 (25%), Positives = 129/392 (32%), Gaps = 83/392 (21%)
Query: 789 PSSCPGDLAPHLMMQSGQLGGDPA---PHTHPHP--PWL----------PRTRSPSLWMG 833
P P PHL Q +L P PH P P P L P++ P L
Sbjct: 786 PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPR 845
Query: 834 GHSYGLGHPALHQNLPPGFPASVAGPV-PSVFPLPQDAPTQLVILPSEPTPHSAPHALAD 892
L P L + PP P P P P P++ P L P EP+ L+
Sbjct: 846 PEESHLS-PELEK--PPLSPRPEKPPEEPGQCPAPEELP--LFPPPGEPS-------LSP 893
Query: 893 VMDQASLWPPMYGGRGPASHMQHPGQLPVYSR------PQLLRQQELYALQQQRAAQFQR 946
++ + +L P G P S + P +LP+ PQL+ L
Sbjct: 894 LLGEPALSEP---GEPPLSPL--PEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAP 948
Query: 947 KPEDQHLDLEEPAQEKAPKSTHKPVAL----TPTAPGAPSPAAGPTKLPPCCHPP----- 997
+LE P K P+A TP +P + P +PP PP
Sbjct: 949 PALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSP 1008
Query: 998 ---------DPKPPASSP------TPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEG 1042
+P PP SP P P + C+ P S P P S + + E
Sbjct: 1009 VGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEA 1068
Query: 1043 Q--------QSTADIITSEPDLPPGYLRPMAGLGFSLPS-----DVHSSNLEDPETMQ-T 1088
+ S + EP PM L PS D S ED +
Sbjct: 1069 ELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGI 1128
Query: 1089 TAPGAQPEPTRT------FLPGEPPPCSPRSL 1114
APG+QPEP +T L G P P L
Sbjct: 1129 DAPGSQPEPGQTPGSLASELKGSPVLLDPEEL 1160
Score = 43.5 bits (101), Expect = 0.003
Identities = 120/561 (21%), Positives = 173/561 (30%), Gaps = 110/561 (19%)
Query: 789 PSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTRSPSLWMGGHSYGLGHPALHQNL 848
PS P LAP ++ P +P P P P + G G P
Sbjct: 2172 PSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPA--QPPMLGASSRPGAGQPGEFHTT 2229
Query: 849 PPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADVMDQASLWPPMYGGRG 908
PPG P P F P+ + +P P + + L PP +G
Sbjct: 2230 PPGTPRHQPS-TPDPFLKPRCPSLDNLAVPESPGVGGGKAS------EPLLSPPPFGESR 2282
Query: 909 PASHMQHP---GQLPVYSRPQL------LRQQELYALQQQRAAQFQRK--PEDQHLDLEE 957
A ++ P Y P L L L+ + F+ P ++ +
Sbjct: 2283 KALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQS 2342
Query: 958 PAQEKAPKSTHKPVALTPTAPG-----APSPAAGPTKLPPCCHPPDPKPPASSPTPPPR- 1011
P P+ AL P+ P P P PP P P PP S PPR
Sbjct: 2343 PGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRS 2402
Query: 1012 ---------------------PSAPCTLNV---CPA------SSPGPGSRVRSAEE---- 1037
P P L+ CP+ SP P SR S +
Sbjct: 2403 LPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDP 2462
Query: 1038 -----------------KNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNL 1080
K G ++ LP G P L +PS + +
Sbjct: 2463 FAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAG---PAGELHAKVPSGQPPNFV 2519
Query: 1081 EDPET---------MQTTAPGAQPEPT---RTFLPGEPPPCSPRSLEEPGLLSGAREATQ 1128
P T M+ T P A EP+ PG PPP S PG G ++T
Sbjct: 2520 RSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTN 2579
Query: 1129 DLAAT----PYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEAT----GQAHSTQGG 1180
AT P + GP + S GL L+ ++L P+ + S + G
Sbjct: 2580 YTVATGNFHPSGSPLGPSSGSTGES--YGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSG 2637
Query: 1181 AREERSREEGEQGPSSGASSQVLE----QRAGSPGALEDEGEQPAPEE---DELEEDELG 1233
+ E + G G+S E Q G G + E E+ + + L ++
Sbjct: 2638 ITSPVEKRE-DPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQ 2696
Query: 1234 QQSMEDSEEDCGGAPDNSHPP 1254
+ ++ +E A PP
Sbjct: 2697 RNTLRQEKETAAAAAGAVGPP 2717
Score = 42.7 bits (99), Expect = 0.005
Identities = 154/680 (22%), Positives = 225/680 (33%), Gaps = 130/680 (19%)
Query: 793 PGDLAPHLMMQSGQLGGDPAPHTHPHPPWL-PRTRSPSLWMGG----HSYGLGHPALHQN 847
PG++ P L S L P P P L P R P H+ G G H
Sbjct: 4062 PGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGS---HGQ 4118
Query: 848 LPPGFPASVAGPVPSVFPLPQ----DAP---TQLVILPSEPTPHSAPHALADVMDQASLW 900
L G +S A VP + P D P TQ ++ P +P P
Sbjct: 4119 LGSG-SSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLER-PMQNNTGPQPPKPG 4176
Query: 901 PPMYGGRG--PASHMQHPGQLPVY------SRPQLL-----RQQELYALQQQRAAQFQRK 947
P + G+G M GQL PQL +QQ+L AL QR Q Q +
Sbjct: 4177 PVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQ-QSQ 4235
Query: 948 PEDQHLDLEEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPT-------------KLP--- 991
Q +EP + +P + P G P P GP +LP
Sbjct: 4236 AVRQTPPYQEPGTQTSP--LQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPP 4293
Query: 992 ------PCCHPPDPKPPASSPTPPPRPS-APCTLNVCPASSPGPGSRVRSAEEKNGEGQQ 1044
P P P PP SSP P RPS P + P + P + + + +
Sbjct: 4294 GALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGP---- 4349
Query: 1045 STADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPG 1104
T EP PPG + P A L + S L + A +PE + + +PG
Sbjct: 4350 ------TLEP--PPGRVSPAAA---QLADTLFSKGLGPWDPPDNLAETQKPEQS-SLVPG 4397
Query: 1105 EPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERGPQGKAADPSPLEGLQELQCAALLE 1164
+ + + E LS +E ++ A + + +P L E
Sbjct: 4398 HLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSE 4457
Query: 1165 AGG------PEATGQAHSTQGGAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGE 1218
AG A ST G+ R+ G Q L+ G+P ED
Sbjct: 4458 AGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQ---GTPSNKEDAAA 4514
Query: 1219 Q----PAPEEDELEEDELGQQSMEDSEEDCGGAPDN-----SHPPRALPGLDALVAATIN 1269
+ P P+ + D L + +ED A + LP + + A +
Sbjct: 4515 RKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFS 4574
Query: 1270 L----------------------GDLPS-----------DSPPDPQPPAASGPPSTVPLP 1296
L G LP+ ++ +P P +S PP+ P
Sbjct: 4575 LFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSV 4634
Query: 1297 HSSGIHGIALLSELADL---AIQRQRSERTVPEEEEDVLAFNLQHLATLAT-AWSLVEAA 1352
++G+ EL + A + SER + + E +L LA L T + E
Sbjct: 4635 QQKMVNGVTPSEELGEHPKDAASARDSERALRDTSE---VKSLDLLAALPTPPHNQTEDV 4691
Query: 1353 GLDSSTAPAQPPTANPCSGP 1372
++S P + P S P
Sbjct: 4692 RMESDEDSDSPDSIVPASSP 4711
Score = 39.7 bits (91), Expect = 0.039
Identities = 39/154 (25%), Positives = 64/154 (41%), Gaps = 34/154 (22%)
Query: 1166 GGPEATGQAHSTQGGAREERSREEGEQGPS-SGASSQVLEQRAGSPGALEDEGEQPAP-- 1222
G P+A G S + +E + ++G+ GP + S+ LE +A +PG ED G + +P
Sbjct: 1802 GTPKAKGDGGSER---KELPTSQKGDDGPDIADEESRGLEGKADTPGP-EDGGVKASPVP 1857
Query: 1223 ----------------EEDELEEDELGQQSMEDSEE---DCGGAPDNSHPPRALPGLDA- 1262
+ D + +EL + +D ++ D G+ H PGL+
Sbjct: 1858 SDPEKPGTPGEGMLSSDLDRISTEELPKMESKDLQQLFKDVLGSEREQHLGCGTPGLEGS 1917
Query: 1263 -------LVAATINLGDLPSDSPPDPQPPAASGP 1289
+ + LG+LPS SP D P P
Sbjct: 1918 RTPLQRPFLQGGLPLGNLPSSSPMDSYPGLCQSP 1951
Score = 37.7 bits (86), Expect = 0.15
Identities = 91/420 (21%), Positives = 141/420 (33%), Gaps = 60/420 (14%)
Query: 918 QLPVYSRPQLLRQQELYAL----------QQQRAAQFQRKPEDQHLDLEEPAQE--KAPK 965
QL + Q L+QQ+ L QQQ+ QFQ++ + Q + L ++ +
Sbjct: 3930 QLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQ 3989
Query: 966 STHKPVALTPTAPGAP-----SPAA-GPTKLPPCCHPPDPKPPASSPT---PPPRPSAPC 1016
+ VAL P P P SP A GPT L P SS P P
Sbjct: 3990 QQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPL 4049
Query: 1017 TLNVCP---ASSPGPGSRVRSAEEK----NGEGQQSTADIITSEPDLPPGYLRPMAGLGF 1069
+ P A+ PG S + + + Q + + P PG + L
Sbjct: 4050 AIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLH 4109
Query: 1070 SLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSL---EEPGLLSGAREA 1126
+ H + ++ P +P+ + G+ P ++L ++P L +
Sbjct: 4110 TAGGGSHGQLGSGSSSEASSVPHLLAQPSVSL--GDQPGSMTQNLLGPQQPMLERPMQNN 4167
Query: 1127 TQDLAATPYPTERGPQG-KAADPSPLEGLQELQCAALLEAG------GPEATGQAHSTQG 1179
T P P + QG P G Q +L P+ Q +
Sbjct: 4168 TGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLM 4227
Query: 1180 GAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMED 1239
+ ++S+ + P +Q G G G P P+ L+E
Sbjct: 4228 QRQLQQSQAVRQTPPYQEPGTQT-SPLQGLLGCQPQLGGFPGPQTGPLQE---------- 4276
Query: 1240 SEEDCGGAPDNSHPPRALPGLDALVAATINLGDL-PSDSPPDPQPPAASGPPSTVPLPHS 1298
G P PPR LP ++ LG + P+ P PQ P PS +P P S
Sbjct: 4277 ----LGAGPRPQGPPR-LPAPPGALSTGPVLGPVHPTPPPSSPQEPKR---PSQLPSPSS 4328
Score = 37.4 bits (85), Expect = 0.20
Identities = 82/385 (21%), Positives = 119/385 (30%), Gaps = 45/385 (11%)
Query: 992 PCCHPPDPKPPASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIIT 1051
P C P P +PT P L V P G ++ G Q +
Sbjct: 367 PVCSRFSPPEPGDTPTDEPD-----ALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGK 421
Query: 1052 SEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSP 1111
+ L P P+ LP S PE T+ P PE +R P E P SP
Sbjct: 422 AGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPP---PEASRLSPPPEELPASP 478
Query: 1112 RSLEEPGLLSGAREATQDLAATPY--PTERGPQGKAADPSPLEGLQELQCAALLEAGGPE 1169
L A ++ L +P P E P + SP L+E + E+
Sbjct: 479 --------LPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSP 530
Query: 1170 A--TGQAHSTQGGAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDEL 1227
A T + + E P + + + E+ P PEE +
Sbjct: 531 ALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPM 590
Query: 1228 EEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAAS 1287
+ EE P P P L SPP P+ S
Sbjct: 591 SPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL-------------SPP-PEDSPMS 636
Query: 1288 GPPSTVPLPHSSGIHGIALLSELADLAIQRQRSERTVPEEEEDVLAFNLQHLATLATAWS 1347
PP P+ + ++ L ++ L+ + S + P EE + S
Sbjct: 637 PPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESP---------TSPPPEAS 687
Query: 1348 LVEAAGLDSSTAPAQPPTANPCSGP 1372
+ DS T+P PP +P S P
Sbjct: 688 RLSPPPEDSPTSP--PPEDSPASPP 710
Score = 37.0 bits (84), Expect = 0.25
Identities = 77/316 (24%), Positives = 101/316 (31%), Gaps = 92/316 (29%)
Query: 842 PALHQNLPPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADVMDQASLWP 901
PALH +PP P ++ P P+ APT + P+ P S AD L P
Sbjct: 2100 PALHLRIPPQ-PGALGSPPPAA------APTIFIGSPTTPAGLSTS---AD----GFLKP 2145
Query: 902 PMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLEEPAQE 961
P GP S PG+L + PQ+ Q P+Q+
Sbjct: 2146 PAGSVPGPDS----PGELFLKLPPQVPAQV--------------------------PSQD 2175
Query: 962 KAPKSTHKPVALT-------------PTAPGAPSPAAGPTKLP----------------P 992
P L PT P PSP P + P
Sbjct: 2176 --------PFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFH 2227
Query: 993 CCHPPDPKPPASSPTPPPRPSAPCTLNVCPASSPGPGSRVRS----AEEKNGEGQQSTAD 1048
P P+ S+P P +P P N+ SPG G S + GE +++
Sbjct: 2228 TTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEV 2287
Query: 1049 IITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLE--DPETMQT--TAPGAQPEPTRTFL-- 1102
P Y P G S S H LE P+ + T +Q EP L
Sbjct: 2288 KKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGL 2347
Query: 1103 -PGEPPPCSPRSLEEP 1117
P EPPP + P
Sbjct: 2348 RPQEPPPAQALAPSPP 2363
Score = 34.3 bits (77), Expect = 1.7
Identities = 42/131 (32%), Positives = 56/131 (42%), Gaps = 38/131 (29%)
Query: 908 GPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQH--------LDLEE-- 957
GP Q LP Y+ L Q ++ +L +Q + +P QH LD+ +
Sbjct: 4853 GPDWLKQFDAVLPGYT---LKSQLDILSLLKQESPA--PEPPTQHSYTYNVSNLDVRQLS 4907
Query: 958 --PAQEKAPKSTHKPVALTPTAPGAPSPAAGPTK----LP--PCCHP--PDPKPPASSP- 1006
P +E +P P +P APSPA+ PT+ LP P P P P P ASSP
Sbjct: 4908 APPPEEPSP----------PPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPE 4957
Query: 1007 --TPPPRPSAP 1015
P PR P
Sbjct: 4958 SARPKPRARPP 4968
Score = 33.5 bits (75), Expect = 2.8
Identities = 74/316 (23%), Positives = 110/316 (34%), Gaps = 72/316 (22%)
Query: 750 DLEAEEERTRLCDDRLGLASRELLLQDSKDRVEFARI-HPPSSCPGDLAPHLMMQSGQLG 808
+LE + +R RL RELL++ R + ++ G + P G G
Sbjct: 2676 ELEKQRQRQRL---------RELLIRQQIQRNTLRQEKETAAAAAGAVGP-----PGSWG 2721
Query: 809 GDPAPHTHPHPPWLPRTRSPSLWMGGHSYGLGHPALHQNLPPGFPASVAGPVPSVFPLPQ 868
+P+ P L R ++P S +G P P+ ++GP+ P
Sbjct: 2722 AEPSS---PAFEQLSRGQTPFAGTQDKSSLVGLP----------PSKLSGPILGPGSFPS 2768
Query: 869 DAPTQLVILPSEPTPHSAPHALADVMDQASLWPPMYGGRGPASHMQHPGQLPV-YSRPQL 927
D S P P + P ++ DV + + G + +PG LP+ + QL
Sbjct: 2769 DDRL------SRPPPPATPSSM-DVNSRQLVG----GSQAFYQRAPYPGSLPLQQQQQQL 2817
Query: 928 LRQQELYALQQQRAAQFQRKPEDQHLDLEEPA--QEKAPKSTHKP----VALTPTAP--- 978
+QQ+ A R A R P +L A A ST P P P
Sbjct: 2818 WQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQF 2877
Query: 979 --------------GAPSPAAGPTKLP---PCCHPPDPKPP------ASSPTPPPRPSAP 1015
G P P GP + P P P P A S PP +PSAP
Sbjct: 2878 IELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAP 2937
Query: 1016 CTLNVCPASSPGPGSR 1031
+ + P P ++
Sbjct: 2938 PAPELNNSLHPTPHTK 2953
Score = 33.1 bits (74), Expect = 3.7
Identities = 73/296 (24%), Positives = 107/296 (36%), Gaps = 74/296 (25%)
Query: 981 PSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAPCTLNVCPAS-----------SPGPG 1029
PS +GP L P P D + + PP P+ P +++V +P PG
Sbjct: 2753 PSKLSGPI-LGPGSFPSDDRL-----SRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPG 2806
Query: 1030 SR-VRSAEEKNGEGQQSTADII-----------TSEPDLPPGYL-RPMAGLGFSLPSDVH 1076
S ++ +++ + QQ+TA T P+L L P+AG+ LP
Sbjct: 2807 SLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGE 2866
Query: 1077 -----SSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSL---EEPGLLSGAREATQ 1128
+ + E G P T PG+ PP PR E+P L A E +
Sbjct: 2867 PVPGPAGPAQFIELRHNVQKGLGPGGTP--FPGQGPPQRPRFYPVSEDPHRL--APEGLR 2922
Query: 1129 DLAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQG--GAREERS 1186
LA + P PQ +A P+P E H T G
Sbjct: 2923 GLAVSGLP----PQKPSAPPAP------------------ELNNSLHPTPHTKGPTLPTG 2960
Query: 1187 REEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEE 1242
E + PSS G P L E + E+ EL++D +++ED EE
Sbjct: 2961 LELVNRPPSS--------TELGRPNPLALEAGKLPCEDPELDDDFDAHKALEDDEE 3008
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 69.3 bits (168), Expect = 5e-11
Identities = 100/372 (26%), Positives = 132/372 (35%), Gaps = 51/372 (13%)
Query: 956 EEP----AQEKAPKSTHKPVALTPTAPGAPSPAAG-PTKLPPCCHPPDPKPPASSPTPPP 1010
EEP + P+ P A PT SPAA PT P +P PA++ PP
Sbjct: 985 EEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPT-------PEEPTSPAAAVPPPE 1037
Query: 1011 RPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFS 1070
P++P P P + V + EE A + T E P P
Sbjct: 1038 EPTSPAAAVPTPEEPTSPAAAVPTPEEPT----SPAAAVPTPEEPTSPAAAVP------- 1086
Query: 1071 LPSDVHSSNLEDPETMQTTAPGA------QPEPTRTFLPGEPPPCSPRSL----EEPGLL 1120
P + S P + T+P A +P +P P SP + EEP
Sbjct: 1087 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFP 1146
Query: 1121 SGA----REATQDLAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHS 1176
+ A E+ A P P E AA P+P E A LE E T A S
Sbjct: 1147 APAVPTPEESASAAVAVPTP-EESASPAAAVPTPAESASFAAVVATLE----EPTSPAAS 1201
Query: 1177 TQGGAREERSREEGEQGPSSGASSQVLEQRAGSPGALE--DEGEQPAPEEDELEEDELGQ 1234
A + EE S AS E+ A A+ +E PA LEE
Sbjct: 1202 VPTPAAMVATLEE---FTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSA 1258
Query: 1235 QSMEDSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAASGPPSTVP 1294
++ EE +P S P P A AA NL + S + P P A+ P ++VP
Sbjct: 1259 AAVLTPEE--LSSPAASVPTPEEPASPA--AAVSNLEEPASPAAAVPTPEVAAIPAASVP 1314
Query: 1295 LPHSSGIHGIAL 1306
P I A+
Sbjct: 1315 TPEVPAIPAAAV 1326
Score = 36.2 bits (82), Expect = 0.43
Identities = 51/202 (25%), Positives = 72/202 (35%), Gaps = 31/202 (15%)
Query: 853 PASVAGPVPSVFPLPQDAPTQLVILPS---EPTPHSAPHALADVMDQASLWPPMYGGRGP 909
P A P P+V P P+++ + V +P+ +P +A A+ A++ + P
Sbjct: 1140 PEEPAFPAPAV-PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSP 1198
Query: 910 ASHMQHPGQL---------PVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLEEPAQ 960
A+ + P + P S P L A + P LEEP
Sbjct: 1199 AASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSN--PEEPTSPAAAVPTLEEPTS 1256
Query: 961 EKA----PKSTHKPVALTPTAPGAPSPAAGPTKL----PPCCHPPDPK----PPASSPTP 1008
A P+ P A PT SPAA + L P P P+ P AS PTP
Sbjct: 1257 SAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTP 1316
Query: 1009 P----PRPSAPCTLNVCPASSP 1026
P + P V P P
Sbjct: 1317 EVPAIPAAAVPPMEEVSPIGVP 1338
>gi|139394604 bromo adjacent homology domain containing 1 [Homo
sapiens]
Length = 780
Score = 68.9 bits (167), Expect = 6e-11
Identities = 60/222 (27%), Positives = 100/222 (45%), Gaps = 10/222 (4%)
Query: 2354 PALLLQTCLTHPVPTLLAQPEALRSKGSGPHAHAQRCFLSRATVAGTGAGSGPSSSSKSK 2413
PA L C VP L++ S P A+ C S +G+ +G SS +
Sbjct: 499 PAHPLLGCPVPSVPPAAEPVPHLQTPTSEPQTVARACPQSAKPPSGSKSGLRTGSSCRHT 558
Query: 2414 LKRKEALSFSKAKELSRRQRP-PSVENRPKISAFLPARQLWKWSGNPTQRRGMKGKARKL 2472
+ K A S K+ R QRP P R + + ++P + + A +
Sbjct: 559 ARSKAARRPSHPKQ-PRVQRPRPRRRRRRRTNGWVPVGAACEKAVYVLDE---PEPAIRK 614
Query: 2473 FYKAIVRGEETLRVGDCAVFLSAGRP-NLPYIGRIESMWESWGSN-MVVKVKWFYHPEET 2530
Y+A+ R ET+RV D + S R + PY+ +I ++WE+ S +++ + W+Y PE
Sbjct: 615 SYQAVERHGETIRVRDTVLLKSGPRKTSTPYVAKISALWENPESGELMMSLLWYYRPEHL 674
Query: 2531 KLGKRQCDGK---NALYQSCHEDENDVQTISHKCQVVAREQY 2569
+ G+ + N ++ S H+D+N V I KC V+ +Y
Sbjct: 675 QGGRSPSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEY 716
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 68.2 bits (165), Expect = 1e-10
Identities = 181/743 (24%), Positives = 239/743 (32%), Gaps = 112/743 (15%)
Query: 675 PGQSERPDCARSREHDTTHGDGEVRQPPVGIAVALARQKDTVSRSEAAYGTNTARQGRAA 734
P + R + + EH TT R+ P L R S A ++ AR G +A
Sbjct: 201 PTEGPRKSVSSASEHSTTEPSPAARRRP-SAGGGLQRPASRSLSSSATPLSSPARSGPSA 259
Query: 735 ------PAFKGGGGPRSTHALDLEAEEERTRLCDDRLGLASRELLLQDSKDRVEFARIHP 788
PA P+ AL + LG S L S + + P
Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPP 319
Query: 789 PSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTRS-PSLWMGGHSYGLGHPALHQN 847
P + L P + S L P P P P P ++ PS
Sbjct: 320 PDNAATPL-PATLPPSPPLA-TPLPLAPPSPSAPPSLQTLPS------------------ 359
Query: 848 LPPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADVMDQASLWPPMYGGR 907
PP P S A P S+ P AP L +P P PH+L QA P
Sbjct: 360 -PPATPPSQAPP--SMTTPPMQAPPSLQTIP----PIQVPHSLTSPSLQAPPSPLALSSL 412
Query: 908 GPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLEEPAQEKAPKST 967
+ + P +S + P L P++ +
Sbjct: 413 QATTSLGSPTLQATHSFLTM-------------------SPRQTQASLTSPSRPASTPPD 453
Query: 968 HKPVALTPTAPGAP------SPAAGPTKLPPCCHP---------PDPKPPASSPTPPPRP 1012
P+ + P +P SPA P P HP P+ P SS PP
Sbjct: 454 SPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLE 513
Query: 1013 S----APCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLG 1068
+ AP +L PAS P Q ++A + T + PP P
Sbjct: 514 TQSSLAPPSLQTPPASLTTPPLE-NLPSLAPPPLQTASAPLTTPHLETPPC---PAPCPL 569
Query: 1069 FSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEP-PPCSPRSLEEPGLLSGAREAT 1127
+ PS + + E P ++ T P A P L G P PP SP L P + A
Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSP--LATPPPQAPPXLAL 627
Query: 1128 QDLAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAG---GPEATGQA-HSTQGGARE 1183
L A P P P A PSP LL+A P QA S
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQA--PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 685
Query: 1184 ERSREEGEQGPSSGASS--QVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSE 1241
S Q P S A+ QV SP + P L L +
Sbjct: 686 SPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744
Query: 1242 EDCGGAPDNSHPPR-----ALPGLDALVAATINLGDLPSDSPPDPQPPAASGPP-STVPL 1295
+P + PPR A P L + +L P PP PPA + PP +P
Sbjct: 745 PPM--SPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS 802
Query: 1296 PHSSGIHGIALLSELADLAIQRQRSERTVPEEEEDVLAFNLQHLATLATAWSLVEAAGLD 1355
P +S G A S A L + T P + VLA L + A ++
Sbjct: 803 PPAS-FPGQAPFSPSASLPMS---PLATPPPQAPPVLAAPLLQVPPSPPASPTLQ----- 853
Query: 1356 SSTAPAQPPTANP---CSGPRLT 1375
AP +PPT P SGPRLT
Sbjct: 854 ---APRRPPTPGPDTSVSGPRLT 873
Score = 65.5 bits (158), Expect = 7e-10
Identities = 98/370 (26%), Positives = 119/370 (32%), Gaps = 90/370 (24%)
Query: 849 PPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPT------PHSAPHALADVMDQASLWPP 902
PP P+S+A P P P P Q LPS P P AP LA QA PP
Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQG--LPSPPLSPLATPPPQAPPXLALPPLQA---PP 634
Query: 903 MYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQ-HLDLEEPAQ- 960
P S + P PQ ++ LQ A F P PA
Sbjct: 635 SPPASPPLSPLATPS-------PQAPNALAVHLLQ----APFSPPPSPPVQAPFSPPASP 683
Query: 961 ----EKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASSP---------- 1006
P S P P PSP A P P PP PP ++P
Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743
Query: 1007 --------TPPPR-------------PSAPCTLNVCPASSPGPGS---------RVRSAE 1036
TPPPR PS P +L + P + P P + + +
Sbjct: 744 SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP 803
Query: 1037 EKNGEGQQ--------STADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDPETMQT 1088
+ GQ + + T P PP P+ + PS S L+ P T
Sbjct: 804 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP---PSPPASPTLQAPRRPPT 860
Query: 1089 TAPGAQ---PEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTE-----RG 1140
P P T PG PP P S LSG A +AT P E G
Sbjct: 861 PGPDTSVSGPRLTLALAPGPPP---PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG 917
Query: 1141 PQGKAADPSP 1150
P+G AA P
Sbjct: 918 PEGGAAASPP 927
Score = 54.3 bits (129), Expect = 2e-06
Identities = 129/581 (22%), Positives = 200/581 (34%), Gaps = 73/581 (12%)
Query: 834 GHSYGLGHPAL-HQNLPPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALAD 892
G + G PA+ ++ G + P PS P P PT+ P + ++ H+ +
Sbjct: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP---PTEG---PRKSVSSASEHSTTE 219
Query: 893 VMDQASLWPPMYGG-RGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQ 951
A P GG + PAS P+ S + A RA +P+ +
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR----SGPSARGTPRAPAHPSQPKPK 275
Query: 952 HLDLEEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPD-----------PK 1000
L P Q P+ P ++ +P+ TK P PPD P
Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPV-PPPDNAATPLPATLPPS 334
Query: 1001 PPASSPTP--PPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPP 1058
PP ++P P PP PSAP +L P+ P S ++ Q+ + T P P
Sbjct: 335 PPLATPLPLAPPSPSAPPSLQTLPSPPATPPS--QAPPSMTTPPMQAPPSLQTIPPIQVP 392
Query: 1059 GYL---------RPMAGLGFSLPSDVHSSNLEDPETMQTTAP-GAQPEPTRTFLPGEPPP 1108
L P+A + + S L+ + T +P Q T P PP
Sbjct: 393 HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP 452
Query: 1109 CSPRSLEEPGLLSGAREATQDLAATPYPTERGPQGKAADP--SPLEGLQELQCAALLEAG 1166
SP L+ P L A+ P T P A P SPL + LQ + L +
Sbjct: 453 DSP-PLQAPLSLP---------ASPPLQTSLSP---AVSPLSSPLT-IHPLQALSSLASH 498
Query: 1167 GPEATGQAHSTQGGAREERSREEGEQGPSSGASSQVLE----------QRAGSPGALEDE 1216
P+A + + Q P + ++ LE Q A +P
Sbjct: 499 SPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHL 558
Query: 1217 GEQPAPEEDELEEDELGQQS-MEDSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPS 1275
P P L+ + ++ P + P A P L L + ++ P
Sbjct: 559 ETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLS----PL 614
Query: 1276 DSPPDPQPPAASGPPSTVP--LPHSSGIHGIALLSELAD--LAIQRQRSERTVPEEEEDV 1331
+PP PP + PP P P S + +A S A LA+ ++ + P
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
Query: 1332 LAFNLQHLATLATAWSLVEAAGLDSSTAPAQPPTANPCSGP 1372
F+ ++ + + A + P Q P + P S P
Sbjct: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 715
Score = 52.4 bits (124), Expect = 6e-06
Identities = 110/480 (22%), Positives = 154/480 (32%), Gaps = 65/480 (13%)
Query: 970 PVALTPTAPGAPSP-------------AAGPTKLPPCCHPPDPKPPASSPTPPPRPSAPC 1016
P LTP PG+P P AAG P A+ P PR
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG--- 78
Query: 1017 TLNVCPASSPGPGSR-VRSAEEKNGEGQ-----QSTADIITSEPDLPPGYLRP----MAG 1066
P S G SR S +G G+ ++T+ S P G RP G
Sbjct: 79 -----PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133
Query: 1067 LGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREA 1126
L S V + + GA+ + T PG P P R G G
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRD-TSGPTPGTPSPAMARRSRAAGTEVGLPRP 192
Query: 1127 TQDLAATPYPTERGP--------QGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQ 1178
+A P P GP + +PSP + L + A
Sbjct: 193 AP--SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250
Query: 1179 GGAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSME 1238
AR S + P+ + + +A P + + AP L L S
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 310
Query: 1239 DSEEDCGGAPDNS----------HPPRA--LPGLDALVAATINLGDLPSD--SPPDPQPP 1284
++ PDN+ PP A LP +A +L LPS +PP PP
Sbjct: 311 GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370
Query: 1285 AASGPPSTVPLPHSSGIHGIALLSELADLAIQRQRSERTVP--EEEEDVLAFNLQHLATL 1342
+ + PP P P I I + L ++Q S + + + + LQ +
Sbjct: 371 SMTTPPMQAP-PSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSF 429
Query: 1343 ATAWSLVEAAGLDSSTAPAQ-PPTANPCSGPRLTPRMQILQRKDTWTPKTKPVCPLKAAI 1401
T A L S + PA PP + P P P LQ T + V PL + +
Sbjct: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQ-----TSLSPAVSPLSSPL 484
Score = 43.1 bits (100), Expect = 0.004
Identities = 83/327 (25%), Positives = 116/327 (35%), Gaps = 42/327 (12%)
Query: 1437 DHERDES-----SRSPARRGPGRPRKRKHSSSLPAPRPTGPLPRSDGKKVKAVRTSLGLL 1491
D++RD++ +R+PA R PG R S P P T R G R L
Sbjct: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPL--- 58
Query: 1492 CAELRGGSGGEPAKKRSKLERSVYAGLQTASVEKAQCKKSSCQGGLAPSVAHRVAQLKPK 1551
AE GG GG + S T+S A +S +G AP +
Sbjct: 59 -AERAGGIGGATIPE-SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG---P 113
Query: 1552 VKSKGLPTGLSS----------FQQKEATPGGRIREKLSRAKSAKVSGATRHPQPKGHGS 1601
V S G +G + +E G+ E R SA +GA R S
Sbjct: 114 VSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKR--SALSAGARRDT------S 165
Query: 1602 RETPRCP----AQPSVAASQEAGNGYDSEDCEGLLGTEAPPREAGLLLHTGASVAVLGPS 1657
TP P A+ S AA E G + TE P + + + + PS
Sbjct: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS----SASEHSTTEPS 221
Query: 1658 PSSVVKMEANQKAKKKKERQGLLGACRLSSPESEVKIKRRSVKAKVGTTLERAPGQ---R 1714
P++ + A ++ R A LSSP R + +A + + G R
Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281
Query: 1715 PPGALGKKKAKGKAKGSLRAEPGATPS 1741
PP +K A G L + P ATPS
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPS 308
Score = 33.1 bits (74), Expect = 3.7
Identities = 22/52 (42%), Positives = 30/52 (57%), Gaps = 4/52 (7%)
Query: 50 PSPLPMASHTASSRLMGSSPASSFMGSFLTSS--LGSAASTHPSGPSSSPPE 99
PSPL ++S A++ L SP SFLT S A+ T PS P+S+PP+
Sbjct: 404 PSPLALSSLQATTSL--GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 66.6 bits (161), Expect = 3e-10
Identities = 92/381 (24%), Positives = 135/381 (35%), Gaps = 36/381 (9%)
Query: 786 IHPPSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTRSPSLWMGGHSYGLGHPALH 845
IHP S + PH + Q+ L + P LP +Y + ALH
Sbjct: 3071 IHPEQSVI--MPPHSITQTVSLSHLSQGEVRMNTPTLPSI----------TYSIRPEALH 3118
Query: 846 QNLPPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADVMDQASLWPPMYG 905
P P + P PQ AP + L S+ P H V A P+
Sbjct: 3119 SPRAPLQPQQIEVRAPQRASTPQPAPAGVPALASQHPPEEEVHYHLPV---ARATAPV-- 3173
Query: 906 GRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLEEPAQEKAPK 965
+ MQ +L Y+ P+ +R + +P ++ P KAP+
Sbjct: 3174 -QSEVLVMQSEYRLHPYTVPRDVR-----IMVHPHVTAVSEQPRAADGVVKVPPASKAPQ 3227
Query: 966 STHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAPCTLNVCPASS 1025
K A TP A AP+P P +P P P P + PS L P +
Sbjct: 3228 QPGKEAAKTPDAKAAPTPTPAPVPVPVPLPAPAPAPHGEARILTVTPSN--QLQGLPLTP 3285
Query: 1026 PGPGSRVRSAEEKNGE--GQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDP 1083
P + +GE + DI T P + + A LPS ++ P
Sbjct: 3286 PVVVTHGVQIVHSSGELFQEYRYGDIRTYHPPAQLTHTQFPAASSVGLPSRTKTAAQGPP 3345
Query: 1084 ETMQTTAPGAQPEPTRTFLPGEP-PPCSPRSLEEPGLLSGAR--EATQDLAATPYPTE-- 1138
+ P P+P ++ P +P PPC P L +PG ++ + +Q+ T E
Sbjct: 3346 PEGEPLQP---PQPVQSTQPAQPAPPCPPSQLGQPGQPPSSKMPQVSQEAKGTQTGVEQP 3402
Query: 1139 RGPQGKA-ADPSPLEGLQELQ 1158
R P G A P P +Q Q
Sbjct: 3403 RLPAGPANRPPEPHTQVQRAQ 3423
Score = 46.2 bits (108), Expect = 4e-04
Identities = 30/58 (51%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
Query: 2312 ARLSVSSSSSGS-STSSSSGSVSTSSLCSSDNEDSSYSSDDEDPALLLQTCLTHPVPT 2368
+R + S S SGS S SSSS S+S+SS SSD+ DSS SS D+ PA +Q+ P PT
Sbjct: 263 SRPTRSPSGSGSRSRSSSSDSISSSSSTSSDSSDSSSSSSDDSPARSVQSAAV-PAPT 319
Score = 45.4 bits (106), Expect = 7e-04
Identities = 147/683 (21%), Positives = 221/683 (32%), Gaps = 91/683 (13%)
Query: 354 PPPLSTAAGSFPCLQLHGGPDGLCPLQDKAPRDLKASGPTFV-PSVGHLADKGRPFQAAE 412
P TAAG GGP G + + T V P +G P +AAE
Sbjct: 1984 PRSQKTAAG--------GGPQGKKGKNEPKVDATRPEATTEVGPQIGVKESSMEP-KAAE 2034
Query: 413 ACAVAGEGKDRHLEGT-MAPDHAAPYGVSYAHLKAEG-----KGERRPGGFEAALNPRLK 466
A + + +DR GT P AP V E +G R + LK
Sbjct: 2035 EEAGSEQKRDRKDAGTDKNPPETAPVEVVEKKPAPEKNSKSKRGRSRNSRLAVDKSASLK 2094
Query: 467 GLDYLSSAGPEASFPGLPKSGLDKSGYFELPTSSQDCARPGHQDPLGGKAPQACCTLDKT 526
+D S A+ G +SG+ + S + P +D L + DK
Sbjct: 2095 NVDAAVSPRGAAAQAGERESGV-------VAVSPEKSESPQKEDGLSSQLKSDPVDPDKE 2147
Query: 527 VGKEAPAGPPGAQKVARIRHQQHLMAAEVEQGGIGAEAKRKSLELASLGYSGPHLPPWGV 586
KE + + + ++ Q L A VE AEA AS Y
Sbjct: 2148 PEKEDVSASGPSPEATQLAKQMELEQA-VEHIAKLAEAS------ASAAYKADAPEGLAP 2200
Query: 587 QAGQGTAMAISEERKAGAYLDPFGSGLQQAALLPQELPAPPDEVSAMKNLLKYSSQALVV 646
+ A SE A A GS + + P+ PAPP + L+ + A +
Sbjct: 2201 EDRDKPAHQASETELAAA----IGSIINDISGEPENFPAPPPYPGESQTDLQPPAGAQAL 2256
Query: 647 GQKAPLVGLGGLKASCIQQEAKFLSSKGPGQSERPDC-------ARSREHDTTHGDGEVR 699
+ + ++ EA SS+ P + P AR +T+H E +
Sbjct: 2257 QPSEEGMETDEAVSGILETEAATESSRPPVNAPDPSAGPTDTKEARGNSSETSHSVPEAK 2316
Query: 700 QPPVGIAVALARQKDTVSRSEAAYGTNTARQGRAAPAFKGGGGPRSTHALDLEAEEERTR 759
+ V L R+ + T R R K P +H + + +
Sbjct: 2317 GSKE-VEVTLVRKDKGRQK--------TTRSRRKRNTNKKVVAPVESHVPESNQAQGESP 2367
Query: 760 LCDDRLGLASRELLLQDSKDRVEFARIHPPSSCPGDLA--PHLMMQSGQLGGDPAPHTHP 817
++ + E ++ + E PP SC DL+ P S ++ + T
Sbjct: 2368 AANEGTTVQHPEAPQEEKQS--EKPHSTPPQSCTSDLSKIPSTENSSQEISVEERTPTKA 2425
Query: 818 H-PPWLPRTRSPSLWMGGHSYGLGHPALHQNLPPGFPASVAGPVPSVFPLPQDAPTQLVI 876
PP LP PP PA V + F + + V
Sbjct: 2426 SVPPDLP-------------------------PPPQPAPVDEEPQARFRVHSIIESDPVT 2460
Query: 877 LPSEPTPHSAPHALADVMDQASLWPPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYAL 936
PS+P S P + A L PP+ G P H P ++ + + RQ+E A
Sbjct: 2461 PPSDP---SIPIPTLPSVTAAKLSPPVASGGIP--HQSPPTKVTEW----ITRQEEPRA- 2510
Query: 937 QQQRAAQFQRKPEDQHLDLEEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHP 996
Q + + +D K A + T+ + A P PC H
Sbjct: 2511 QSTPSPALPPDTKASDVDTSSSTLRKILMDPKYVSATSVTSTSVTTAIAEPVSAAPCLHE 2570
Query: 997 PDPKPPASSPTPPPRPSAPCTLN 1019
P PP S P +AP N
Sbjct: 2571 A-PPPPVDSKKPLEEKTAPPVTN 2592
Score = 41.6 bits (96), Expect = 0.010
Identities = 66/283 (23%), Positives = 92/283 (32%), Gaps = 55/283 (19%)
Query: 853 PASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADVMDQAS--------LWPPMY 904
P + A P P+ P+P P P P APH A ++ L PP+
Sbjct: 3237 PDAKAAPTPTPAPVPVPVPL--------PAPAPAPHGEARILTVTPSNQLQGLPLTPPVV 3288
Query: 905 --------GGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLE 956
G G + Y P L + AA P +
Sbjct: 3289 VTHGVQIVHSSGELFQEYRYGDIRTYHPPAQLTHTQF------PAASSVGLPSRTKTAAQ 3342
Query: 957 EPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASSP------TPPP 1010
P E P +PV T P P+P P++L PP K P S T
Sbjct: 3343 GPPPEGEPLQPPQPVQ--STQPAQPAPPCPPSQLGQPGQPPSSKMPQVSQEAKGTQTGVE 3400
Query: 1011 RPSAPCTLNVCPASSPG-PGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGF 1069
+P P PA+ P P ++V+ A+ + G + ++ +PDLP
Sbjct: 3401 QPRLPAG----PANRPPEPHTQVQRAQAETGPTSFPSPVSVSMKPDLP-----------V 3445
Query: 1070 SLPSDVHSSN-LEDPETMQTTAPGAQPEPTRTFLPGEPPPCSP 1111
SLP+ L P T + P P F P SP
Sbjct: 3446 SLPTQTAPKQPLFVPTTSGPSTPPGLVLPHTEFQPAPKQDSSP 3488
Score = 34.7 bits (78), Expect = 1.3
Identities = 50/227 (22%), Positives = 83/227 (36%), Gaps = 27/227 (11%)
Query: 1090 APGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERG-PQGKAADP 1148
AP P ++T L PP ++L+ EA + T TE P A DP
Sbjct: 2235 APPPYPGESQTDLQ---PPAGAQALQPSEEGMETDEAVSGILETEAATESSRPPVNAPDP 2291
Query: 1149 S--PLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGEQGPSSGASSQ--VLE 1204
S P + + ++ PEA G R+++ R++ + +++ V
Sbjct: 2292 SAGPTDTKEARGNSSETSHSVPEAKGSKEVEVTLVRKDKGRQKTTRSRRKRNTNKKVVAP 2351
Query: 1205 QRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDALV 1264
+ P + + +GE PA E + Q + SE+ +S PP++ + +
Sbjct: 2352 VESHVPESNQAQGESPAANEGTTVQHPEAPQEEKQSEKP------HSTPPQSCTSDLSKI 2405
Query: 1265 AATINLGD-------------LPSDSPPDPQPPAASGPPSTVPLPHS 1298
+T N +P D PP PQP P HS
Sbjct: 2406 PSTENSSQEISVEERTPTKASVPPDLPPPPQPAPVDEEPQARFRVHS 2452
>gi|83921602 solute carrier family 38, member 10 isoform a [Homo
sapiens]
Length = 1119
Score = 62.4 bits (150), Expect = 6e-09
Identities = 114/482 (23%), Positives = 167/482 (34%), Gaps = 84/482 (17%)
Query: 816 HPHPPWLPRTRSPSLWMGGHSYGLGHPALHQNLPPGFPASVAGPVPSVF------PLPQD 869
HP P + + L +GG G P PPG A G PLP +
Sbjct: 604 HPRPQAVLSEQQNGLAVGGGEKAKGGP------PPGNAAGDTGQPAEDSDHGGKPPLPAE 657
Query: 870 APTQLVILPSEPTPHSAPHALADVMDQASLWPPMYGGRGPASHMQHPGQLPVYSRPQLLR 929
P LP EP +++A GG AS ++ G+ + LL+
Sbjct: 658 KPAPGPGLPPEPREQRD-------VERA-------GGNQAASQLEEAGRAEMLDHAVLLQ 703
Query: 930 QQELYALQQQRAAQFQRK----PEDQHLDLEEPAQE------KAPKSTHKPVALTPTAPG 979
+ +QQ+R Q K E+QH ++ + QE + + +P A P
Sbjct: 704 VIKEQQVQQKRLLDQQEKLLAVIEEQHKEIHQQRQEDEEDKPRQVEVHQEPGAAVPRGQE 763
Query: 980 APSPAAGPT--KLPPCCHPPDPKPPASSPTPP--------PRPSAPCTLNVCPASSPGPG 1029
AP A T LPP P + P P P P + GP
Sbjct: 764 APEGKARETVENLPPLPLDPVLRAPGGRPAPSQDLNQRSLEHSEGPVGRDPAGPPDGGPD 823
Query: 1030 SRVRSAEEKNGEGQQSTAD-IITSEPDLPPGYLR-PMAGLGFSLPSDVHSSNLEDPETMQ 1087
+ R+A+ K +GQ+ A + +LP G + P+ E P Q
Sbjct: 824 TEPRAAQAKLRDGQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQ 883
Query: 1088 TTAPGAQPEPTRTFLPGEPPPCSPRSL--EEPGLLSGAREATQDLAATPYPTER------ 1139
G+Q PG+ + S+ E L++G T D P R
Sbjct: 884 DVTGGSQDRKK----PGKEVAATGTSILKEANWLVAGPGAETGDPRMKPKQVSRDLGLAA 939
Query: 1140 ----GPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGEQGPS 1195
G +G AA P + EL+ + E GG + H GG E R G+ P
Sbjct: 940 DLPGGAEGAAAQPQAVLRQPELRVISDGEQGGQQGHRLDH---GGHLEMRKARGGDHVPV 996
Query: 1196 SGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPR 1255
S + R G A+++ ++P P ELG + G PDN+ P R
Sbjct: 997 SHE-----QPRGGEDAAVQEPRQRPEP--------ELGLKRAVPG----GQRPDNAKPNR 1039
Query: 1256 AL 1257
L
Sbjct: 1040 DL 1041
Score = 37.7 bits (86), Expect = 0.15
Identities = 45/186 (24%), Positives = 68/186 (36%), Gaps = 23/186 (12%)
Query: 1170 ATGQAHSTQGGAR-----EERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEE 1224
A G+A QG ER ++E EQG + +R G ALE+ G+ P +
Sbjct: 527 AGGKAPGVQGQMAPPLPDSEREKQEPEQGE--------VGKRPGQAQALEEAGDLPEDPQ 578
Query: 1225 DELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPP 1284
E D GQ +++ ++ED G HP + + G+ PP
Sbjct: 579 KVPEAD--GQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAA 636
Query: 1285 AASGPPS-------TVPLPHSSGIHGIALLSELADLA-IQRQRSERTVPEEEEDVLAFNL 1336
+G P+ PLP G L E + ++R + + EE A L
Sbjct: 637 GDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEEAGRAEML 696
Query: 1337 QHLATL 1342
H L
Sbjct: 697 DHAVLL 702
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 62.4 bits (150), Expect = 6e-09
Identities = 170/750 (22%), Positives = 240/750 (32%), Gaps = 150/750 (20%)
Query: 849 PPGFPA-SVAGPVPSVFPL-PQDAPT--QLVILPSEPT---------------------- 882
PPG P GP PS + PQ +PT Q P PT
Sbjct: 201 PPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP 260
Query: 883 ---PHSAPH----ALADVMDQAS----LWPPMYGGRGPASH-------MQHPGQLPVYSR 924
PH +PH L Q S PP++G P H +QHPG +
Sbjct: 261 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL 320
Query: 925 PQLLRQQE---------------LYALQQQRAAQFQRKPEDQHLDLEEPAQE--KAPKST 967
P Q + L Q A Q Q+ P +Q L A K P +T
Sbjct: 321 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT 380
Query: 968 HKPVALTPTAPGAPSPAAGPT------KLPPCCHPPDPKPPASSPTPPPRPSAPCTLNVC 1021
P P A P +GP+ LPP PP KP +S T P + P L +
Sbjct: 381 PIPQLPAPQAHKHPPHLSGPSPFSMNANLPP---PPALKPLSSLSTHHPPSAHPPPLQLM 437
Query: 1022 PASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLE 1081
P S P P S + +T +LPP P A P+ +H +
Sbjct: 438 PQSQPLPSSPAQPPG-------------LTQSQNLPP----PPAS---HPPTGLHQVAPQ 477
Query: 1082 DPETMQTTAPGAQPE------PTRTFLPGEP-----PPCSPRSLEEPGLLSGA------- 1123
P PG P P+ + P P PPCS + + G+
Sbjct: 478 PPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTV 537
Query: 1124 --REATQDLAATPYPTERGPQGKAADP----SPLEGLQELQCAALLEAG--GPEATGQAH 1175
+E D A P P+ + +P +P Q + L+ G T
Sbjct: 538 QIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYF 597
Query: 1176 STQGGAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQ 1235
G++ + REE + A + E+R E E E+ E E E
Sbjct: 598 MPLAGSKLAKKREEAIEKAKREAEQKAREEREREK-EKEKEREREREREREAERAAKASS 656
Query: 1236 SMED---SEEDCGG----APDNSHPPRALPGLDALVAA-TINLGDLPSDSPPDPQPPAAS 1287
S + S+ G P PP + + + T L L + P P
Sbjct: 657 SAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNR 716
Query: 1288 GPPSTVPLP--------HSSGIHGI---ALLSELADLAI-QRQRSERTVPEEEEDVLAFN 1335
P +PL H G++ + EL + I +R+ ER + E +
Sbjct: 717 NHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVK 776
Query: 1336 LQHLATLATAWSLVEAAGLDSSTAPAQPPTANPCSGPRLTPRMQILQRKDTWT--PKTKP 1393
L L A + +E S A PPTA P P + L+R+ P+ +P
Sbjct: 777 PPELDPLHPAANPMEHFARHS--ALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRP 834
Query: 1394 VC--PLKAAIDRLDTQEVGMRVR--LAELQRRYKEKQRELARLQRKHDHERDESSRSPAR 1449
P + A +R+ + + LA LQ H H +
Sbjct: 835 EMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGS 894
Query: 1450 RGPGRP-----RKRKHSSSLPAPRPTGPLP 1474
GP P H + P P T P P
Sbjct: 895 AGPVHPLVDPLTAGPHLARFPYPPGTLPNP 924
Score = 37.4 bits (85), Expect = 0.20
Identities = 72/336 (21%), Positives = 102/336 (30%), Gaps = 59/336 (17%)
Query: 976 TAPGAPSPAAGPTKL------------PPCCHPPDPKPPASSPTPPPRPSAPCTLNVCPA 1023
T+P PSP + PP P PA S PP P P T P+
Sbjct: 157 TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP-TPGPTPS 215
Query: 1024 SSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDP 1083
++ P +A + + Q TA + P +++ L P H
Sbjct: 216 ATAVPPQGSPTASQAPNQPQAPTAPV-------PHTHIQQAPALHPQRPPSPH------- 261
Query: 1084 ETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERG-PQ 1142
P P P L G S S +P L L A P G PQ
Sbjct: 262 -----PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 316
Query: 1143 GKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGEQGPSSGASSQV 1202
P +G L + A P + Q ++Q + ++ E P+ A +
Sbjct: 317 PFGLPPQASQGQAPLGTSP--AAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHI 374
Query: 1203 LEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDA 1262
P + PAP+ + G + N PP AL L +
Sbjct: 375 ------KPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA--------NLPPPPALKPLSS 420
Query: 1263 LVAATINLGDLPSDSPPDPQPPAASGPPSTVPLPHS 1298
L + PP PP P + PLP S
Sbjct: 421 ----------LSTHHPPSAHPPPLQLMPQSQPLPSS 446
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 62.4 bits (150), Expect = 6e-09
Identities = 170/750 (22%), Positives = 240/750 (32%), Gaps = 150/750 (20%)
Query: 849 PPGFPA-SVAGPVPSVFPL-PQDAPT--QLVILPSEPT---------------------- 882
PPG P GP PS + PQ +PT Q P PT
Sbjct: 755 PPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP 814
Query: 883 ---PHSAPH----ALADVMDQAS----LWPPMYGGRGPASH-------MQHPGQLPVYSR 924
PH +PH L Q S PP++G P H +QHPG +
Sbjct: 815 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL 874
Query: 925 PQLLRQQE---------------LYALQQQRAAQFQRKPEDQHLDLEEPAQE--KAPKST 967
P Q + L Q A Q Q+ P +Q L A K P +T
Sbjct: 875 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT 934
Query: 968 HKPVALTPTAPGAPSPAAGPT------KLPPCCHPPDPKPPASSPTPPPRPSAPCTLNVC 1021
P P A P +GP+ LPP PP KP +S T P + P L +
Sbjct: 935 PIPQLPAPQAHKHPPHLSGPSPFSMNANLPP---PPALKPLSSLSTHHPPSAHPPPLQLM 991
Query: 1022 PASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLE 1081
P S P P S + +T +LPP P A P+ +H +
Sbjct: 992 PQSQPLPSSPAQPPG-------------LTQSQNLPP----PPAS---HPPTGLHQVAPQ 1031
Query: 1082 DPETMQTTAPGAQPE------PTRTFLPGEP-----PPCSPRSLEEPGLLSGA------- 1123
P PG P P+ + P P PPCS + + G+
Sbjct: 1032 PPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTV 1091
Query: 1124 --REATQDLAATPYPTERGPQGKAADP----SPLEGLQELQCAALLEAG--GPEATGQAH 1175
+E D A P P+ + +P +P Q + L+ G T
Sbjct: 1092 QIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYF 1151
Query: 1176 STQGGAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQ 1235
G++ + REE + A + E+R E E E+ E E E
Sbjct: 1152 MPLAGSKLAKKREEAIEKAKREAEQKAREEREREK-EKEKEREREREREREAERAAKASS 1210
Query: 1236 SMED---SEEDCGG----APDNSHPPRALPGLDALVAA-TINLGDLPSDSPPDPQPPAAS 1287
S + S+ G P PP + + + T L L + P P
Sbjct: 1211 SAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNR 1270
Query: 1288 GPPSTVPLP--------HSSGIHGI---ALLSELADLAI-QRQRSERTVPEEEEDVLAFN 1335
P +PL H G++ + EL + I +R+ ER + E +
Sbjct: 1271 NHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVK 1330
Query: 1336 LQHLATLATAWSLVEAAGLDSSTAPAQPPTANPCSGPRLTPRMQILQRKDTWT--PKTKP 1393
L L A + +E S A PPTA P P + L+R+ P+ +P
Sbjct: 1331 PPELDPLHPAANPMEHFARHS--ALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRP 1388
Query: 1394 VC--PLKAAIDRLDTQEVGMRVR--LAELQRRYKEKQRELARLQRKHDHERDESSRSPAR 1449
P + A +R+ + + LA LQ H H +
Sbjct: 1389 EMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGS 1448
Query: 1450 RGPGRP-----RKRKHSSSLPAPRPTGPLP 1474
GP P H + P P T P P
Sbjct: 1449 AGPVHPLVDPLTAGPHLARFPYPPGTLPNP 1478
Score = 37.4 bits (85), Expect = 0.20
Identities = 72/336 (21%), Positives = 102/336 (30%), Gaps = 59/336 (17%)
Query: 976 TAPGAPSPAAGPTKL------------PPCCHPPDPKPPASSPTPPPRPSAPCTLNVCPA 1023
T+P PSP + PP P PA S PP P P T P+
Sbjct: 711 TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP-TPGPTPS 769
Query: 1024 SSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDP 1083
++ P +A + + Q TA + P +++ L P H
Sbjct: 770 ATAVPPQGSPTASQAPNQPQAPTAPV-------PHTHIQQAPALHPQRPPSPH------- 815
Query: 1084 ETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERG-PQ 1142
P P P L G S S +P L L A P G PQ
Sbjct: 816 -----PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870
Query: 1143 GKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGEQGPSSGASSQV 1202
P +G L + A P + Q ++Q + ++ E P+ A +
Sbjct: 871 PFGLPPQASQGQAPLGTSP--AAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHI 928
Query: 1203 LEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDA 1262
P + PAP+ + G + N PP AL L +
Sbjct: 929 ------KPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA--------NLPPPPALKPLSS 974
Query: 1263 LVAATINLGDLPSDSPPDPQPPAASGPPSTVPLPHS 1298
L + PP PP P + PLP S
Sbjct: 975 ----------LSTHHPPSAHPPPLQLMPQSQPLPSS 1000
Score = 35.4 bits (80), Expect = 0.74
Identities = 59/309 (19%), Positives = 101/309 (32%), Gaps = 76/309 (24%)
Query: 989 KLPPCCHPPDPKPPASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTAD 1048
+LPP P DP P P ++ S G S +RS +K
Sbjct: 541 ELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKK---------- 590
Query: 1049 IITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPP 1108
+P P G P + D+ SS P T++ ++ E +
Sbjct: 591 ----QPASPDGRTSP-------INEDIRSSGRNSPSAASTSSNDSKAETVKK-------- 631
Query: 1109 CSPRSLEEPGLLSGAREATQDLAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGP 1168
+ + ++ A++P + + + K A + +E + +
Sbjct: 632 --------------SAKKVKEEASSPLKSNKRQREKVASDT-----EEADRTSSKKTKTQ 672
Query: 1169 EATGQAHSTQGGAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELE 1228
E + ++G SR ++G SS + R+ SP P+P+++E +
Sbjct: 673 EISRPNSPSEGEGESSDSRSVNDEG-SSDPKDIDQDNRSTSPSI-------PSPQDNESD 724
Query: 1229 EDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDSPP-DPQPPAAS 1287
D QQ M ++ AP P PS +PP PQ P
Sbjct: 725 SDSSAQQQMLQAQPPALQAPTGVTPA-------------------PSSAPPGTPQLPTPG 765
Query: 1288 GPPSTVPLP 1296
PS +P
Sbjct: 766 PTPSATAVP 774
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 62.4 bits (150), Expect = 6e-09
Identities = 170/750 (22%), Positives = 240/750 (32%), Gaps = 150/750 (20%)
Query: 849 PPGFPA-SVAGPVPSVFPL-PQDAPT--QLVILPSEPT---------------------- 882
PPG P GP PS + PQ +PT Q P PT
Sbjct: 755 PPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP 814
Query: 883 ---PHSAPH----ALADVMDQAS----LWPPMYGGRGPASH-------MQHPGQLPVYSR 924
PH +PH L Q S PP++G P H +QHPG +
Sbjct: 815 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL 874
Query: 925 PQLLRQQE---------------LYALQQQRAAQFQRKPEDQHLDLEEPAQE--KAPKST 967
P Q + L Q A Q Q+ P +Q L A K P +T
Sbjct: 875 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT 934
Query: 968 HKPVALTPTAPGAPSPAAGPT------KLPPCCHPPDPKPPASSPTPPPRPSAPCTLNVC 1021
P P A P +GP+ LPP PP KP +S T P + P L +
Sbjct: 935 PIPQLPAPQAHKHPPHLSGPSPFSMNANLPP---PPALKPLSSLSTHHPPSAHPPPLQLM 991
Query: 1022 PASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLE 1081
P S P P S + +T +LPP P A P+ +H +
Sbjct: 992 PQSQPLPSSPAQPPG-------------LTQSQNLPP----PPAS---HPPTGLHQVAPQ 1031
Query: 1082 DPETMQTTAPGAQPE------PTRTFLPGEP-----PPCSPRSLEEPGLLSGA------- 1123
P PG P P+ + P P PPCS + + G+
Sbjct: 1032 PPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTV 1091
Query: 1124 --REATQDLAATPYPTERGPQGKAADP----SPLEGLQELQCAALLEAG--GPEATGQAH 1175
+E D A P P+ + +P +P Q + L+ G T
Sbjct: 1092 QIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYF 1151
Query: 1176 STQGGAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQ 1235
G++ + REE + A + E+R E E E+ E E E
Sbjct: 1152 MPLAGSKLAKKREEAIEKAKREAEQKAREEREREK-EKEKEREREREREREAERAAKASS 1210
Query: 1236 SMED---SEEDCGG----APDNSHPPRALPGLDALVAA-TINLGDLPSDSPPDPQPPAAS 1287
S + S+ G P PP + + + T L L + P P
Sbjct: 1211 SAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNR 1270
Query: 1288 GPPSTVPLP--------HSSGIHGI---ALLSELADLAI-QRQRSERTVPEEEEDVLAFN 1335
P +PL H G++ + EL + I +R+ ER + E +
Sbjct: 1271 NHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVK 1330
Query: 1336 LQHLATLATAWSLVEAAGLDSSTAPAQPPTANPCSGPRLTPRMQILQRKDTWT--PKTKP 1393
L L A + +E S A PPTA P P + L+R+ P+ +P
Sbjct: 1331 PPELDPLHPAANPMEHFARHS--ALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRP 1388
Query: 1394 VC--PLKAAIDRLDTQEVGMRVR--LAELQRRYKEKQRELARLQRKHDHERDESSRSPAR 1449
P + A +R+ + + LA LQ H H +
Sbjct: 1389 EMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGS 1448
Query: 1450 RGPGRP-----RKRKHSSSLPAPRPTGPLP 1474
GP P H + P P T P P
Sbjct: 1449 AGPVHPLVDPLTAGPHLARFPYPPGTLPNP 1478
Score = 37.4 bits (85), Expect = 0.20
Identities = 72/336 (21%), Positives = 102/336 (30%), Gaps = 59/336 (17%)
Query: 976 TAPGAPSPAAGPTKL------------PPCCHPPDPKPPASSPTPPPRPSAPCTLNVCPA 1023
T+P PSP + PP P PA S PP P P T P+
Sbjct: 711 TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP-TPGPTPS 769
Query: 1024 SSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDP 1083
++ P +A + + Q TA + P +++ L P H
Sbjct: 770 ATAVPPQGSPTASQAPNQPQAPTAPV-------PHTHIQQAPALHPQRPPSPH------- 815
Query: 1084 ETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERG-PQ 1142
P P P L G S S +P L L A P G PQ
Sbjct: 816 -----PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870
Query: 1143 GKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGEQGPSSGASSQV 1202
P +G L + A P + Q ++Q + ++ E P+ A +
Sbjct: 871 PFGLPPQASQGQAPLGTSP--AAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHI 928
Query: 1203 LEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDA 1262
P + PAP+ + G + N PP AL L +
Sbjct: 929 ------KPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA--------NLPPPPALKPLSS 974
Query: 1263 LVAATINLGDLPSDSPPDPQPPAASGPPSTVPLPHS 1298
L + PP PP P + PLP S
Sbjct: 975 ----------LSTHHPPSAHPPPLQLMPQSQPLPSS 1000
Score = 35.4 bits (80), Expect = 0.74
Identities = 59/309 (19%), Positives = 101/309 (32%), Gaps = 76/309 (24%)
Query: 989 KLPPCCHPPDPKPPASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTAD 1048
+LPP P DP P P ++ S G S +RS +K
Sbjct: 541 ELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKK---------- 590
Query: 1049 IITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPP 1108
+P P G P + D+ SS P T++ ++ E +
Sbjct: 591 ----QPASPDGRTSP-------INEDIRSSGRNSPSAASTSSNDSKAETVKK-------- 631
Query: 1109 CSPRSLEEPGLLSGAREATQDLAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGP 1168
+ + ++ A++P + + + K A + +E + +
Sbjct: 632 --------------SAKKVKEEASSPLKSNKRQREKVASDT-----EEADRTSSKKTKTQ 672
Query: 1169 EATGQAHSTQGGAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELE 1228
E + ++G SR ++G SS + R+ SP P+P+++E +
Sbjct: 673 EISRPNSPSEGEGESSDSRSVNDEG-SSDPKDIDQDNRSTSPSI-------PSPQDNESD 724
Query: 1229 EDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDSPP-DPQPPAAS 1287
D QQ M ++ AP P PS +PP PQ P
Sbjct: 725 SDSSAQQQMLQAQPPALQAPTGVTPA-------------------PSSAPPGTPQLPTPG 765
Query: 1288 GPPSTVPLP 1296
PS +P
Sbjct: 766 PTPSATAVP 774
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 62.0 bits (149), Expect = 7e-09
Identities = 196/944 (20%), Positives = 326/944 (34%), Gaps = 209/944 (22%)
Query: 948 PEDQHLDLEEPAQEKAPKS--THKPVALTPTAPGAPSPAAGPTKLPPCCHPPDP------ 999
P+ Q + Q+ PKS + +P + PG P GPT+ P H P
Sbjct: 220 PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDAS 279
Query: 1000 ---------------KPPASSPTPP----PRPSAPCTLNVCPASSPG-----PGSRVRSA 1035
KP SP+ P P P P PA PG PG A
Sbjct: 280 RPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKP------PAQQPGHEKSQPGPAKPPA 333
Query: 1036 EEKNGEGQQSTADIITSEPDLPPGYLRPMA-GLGFSLP------SDVHSSNLEDPETMQT 1088
+ + P PPG +P A LG + P S+ SS P+ +
Sbjct: 334 QPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL-A 392
Query: 1089 TAPGAQPEPTRTFLPGEPPP---CSPRSL-EEPGLLSGAREATQDLAATPYPTERGPQGK 1144
PG P + P +PP +P+ L ++PGL S A+ P PT+ Q
Sbjct: 393 QPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK--------APGPTKTPVQQP 444
Query: 1145 AADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEG--EQGPSSGASSQV 1202
P + GP G+ + Q G + S+ G + P ++
Sbjct: 445 GPGKIP------------AQQAGP---GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP 489
Query: 1203 LEQRAGS-------PGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPR 1255
Q+ GS PG+ + +QP P + ++ + S++ P P
Sbjct: 490 PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQP---GSTKPPSQQPGSAKPSAQQPSP 546
Query: 1256 ALPGLDALVAATINLG-----DLPSDSPPDPQPPAASGPPSTVPLPHSSGIHGIALLSEL 1310
A P G P+ SP QPP+ P + PL +++ +
Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELL-------- 598
Query: 1311 ADLAIQRQRSERTVPEEEEDVLA---FNLQHLATLATAW-----SLVEAAGLDSSTAPAQ 1362
L + + + T E + V + FN T W + A G D + P+
Sbjct: 599 --LHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSS 656
Query: 1363 PPTANPCSGPRL-TPRMQILQRKDTWTPKTKPVCPLKAAIDRLDTQEVGMRVRLAELQRR 1421
P P+L T + +P+ + P K A + D +
Sbjct: 657 PQ-------PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKA-----------P 698
Query: 1422 YKEKQRELARLQRKHDHERDESSRSPARRGPGRPRKRKHSSSLPAPRPTGPLPRSDGKKV 1481
+K L + H ++ + P +P K S+P+ + P+ K+
Sbjct: 699 EPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK-EPSVPSEQDKAPVADDKPKQP 757
Query: 1482 KAVRTSLGLLCAELRGGSGGEPAKK-RSKLERSVYAGLQTASVEKAQC------KKSSCQ 1534
K V+ + L+ + P+ K +S+ E L+T S + +Q K S
Sbjct: 758 KMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD 817
Query: 1535 GGLAP---SVAHRVAQLKPKVKSKGLPTGLSSFQQKEATPGGRIREKLSRAKSAKVSGAT 1591
P S + ++ P +SKG QK+ P + +E+ +A++
Sbjct: 818 SKAIPRPASDSKIISHPGPSSESKG---------QKQVDPVQK-KEEPKKAQTKMSPKPD 867
Query: 1592 RHPQPKGHGSRETPRCPAQPSVAASQEAGNGYDSEDCEGL-LG--TEAP------PRE-- 1640
P PKG + PR A +V Q++ + L LG T+AP P+E
Sbjct: 868 AKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETV 927
Query: 1641 AGLLLHTGASVAVLGPSPSSVVKMEANQKAKKKKERQGLLGACRLSSPESEVKIKRRSVK 1700
G L GAS+ + L+ P S+
Sbjct: 928 TGKLFGFGASIF---------------------SQASNLISTAGQPGPHSQ--------- 957
Query: 1701 AKVGTTLERAPG-QRPPGALGKKKAKGKAKGSLRAEPGATPSRDALFNPSRAFACREEGS 1759
+ G +++AP +PP + G K+ G+A + P+++ ++E
Sbjct: 958 SGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPA----------------PAKSIPVKKETK 1001
Query: 1760 QLASERLK-RATRKGTVLQPVLRRKNGAL--SITLATRNAKAIL 1800
A+E+L+ +A + TV + +K + S +L KA+L
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVL 1045
Score = 38.9 bits (89), Expect = 0.067
Identities = 43/170 (25%), Positives = 65/170 (38%), Gaps = 29/170 (17%)
Query: 945 QRKPEDQHLDLEEPAQEKAP-------KSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPP 997
Q KP Q L P+ P +S+ ++ P P P P P PP PP
Sbjct: 2369 QEKPASQ-LPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP---PP 2424
Query: 998 DPKPPASSPTPPPRPSAPCTLNVCPASSPGP----GSRVRSAEEKNGEGQQSTADIITSE 1053
P PP +SP P P T+ P ++ P + + + G T T+
Sbjct: 2425 PPLPPPTSPKPTILPKKKLTV-ASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP 2483
Query: 1054 PDLPPGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLP 1103
P +PP +P S+PS + ++ +P + P P+P LP
Sbjct: 2484 PPVPP---KPS-----SIPSGLVFTHRPEP-----SKPPIAPKPVIPQLP 2520
Score = 37.0 bits (84), Expect = 0.25
Identities = 84/450 (18%), Positives = 145/450 (32%), Gaps = 87/450 (19%)
Query: 954 DLEEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPS 1013
DL + + K P P+ PT G+PS A K PP S P PP PS
Sbjct: 693 DLSKAPEPKKPP----PLVKQPTLHGSPSAKA---KQPP------EADSLSKPAPPKEPS 739
Query: 1014 APCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADII-----TSEPDLPPGYLRPMAGLG 1068
P + P + P K + + T D++ T++PD+P ++ A
Sbjct: 740 VPSEQDKAPVADDKP---------KQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEK 790
Query: 1069 FSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCS-PRSLEEPGLLSGAREAT 1127
+ P + + + + ++ T P ++ P P S + + PG S ++
Sbjct: 791 TTPP--LKTDSAKPSQSFPPTGEKVSPFDSKAI----PRPASDSKIISHPGPSSESKGQK 844
Query: 1128 QDLAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSR 1187
Q P + P+ SP + + + G GQ T
Sbjct: 845 Q---VDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP--------- 892
Query: 1188 EEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGA 1247
+Q P S+ GS + QP ++ + G + S+ +
Sbjct: 893 ---QQSPKPQEQSRRFSLNLGS--ITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 1248 PDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAASGPPSTVPLPHSSGIHGIALL 1307
P + G A + +P QPP + GPP + + I +
Sbjct: 948 TAGQPGPHSQSGPGAPM----------KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVK 997
Query: 1308 SELADLAIQRQRSERTVPEEEEDVLAFNLQHLATLATAWSLVEAAGLDSSTAPAQPPTAN 1367
E + +E+ P+ E +A + + +PP
Sbjct: 998 KE-----TKAPAAEKLEPKAE---------------------QAPTVKRTETEKKPPPIK 1031
Query: 1368 PCSGPRLTPRMQILQRKDTWTPKTKPVCPL 1397
P+ +L K +PK + CPL
Sbjct: 1032 DSKSLTAEPQKAVLPTKLEKSPKPESTCPL 1061
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 62.0 bits (149), Expect = 7e-09
Identities = 196/944 (20%), Positives = 326/944 (34%), Gaps = 209/944 (22%)
Query: 948 PEDQHLDLEEPAQEKAPKS--THKPVALTPTAPGAPSPAAGPTKLPPCCHPPDP------ 999
P+ Q + Q+ PKS + +P + PG P GPT+ P H P
Sbjct: 220 PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDAS 279
Query: 1000 ---------------KPPASSPTPP----PRPSAPCTLNVCPASSPG-----PGSRVRSA 1035
KP SP+ P P P P PA PG PG A
Sbjct: 280 RPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKP------PAQQPGHEKSQPGPAKPPA 333
Query: 1036 EEKNGEGQQSTADIITSEPDLPPGYLRPMA-GLGFSLP------SDVHSSNLEDPETMQT 1088
+ + P PPG +P A LG + P S+ SS P+ +
Sbjct: 334 QPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL-A 392
Query: 1089 TAPGAQPEPTRTFLPGEPPP---CSPRSL-EEPGLLSGAREATQDLAATPYPTERGPQGK 1144
PG P + P +PP +P+ L ++PGL S A+ P PT+ Q
Sbjct: 393 QPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK--------APGPTKTPVQQP 444
Query: 1145 AADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEG--EQGPSSGASSQV 1202
P + GP G+ + Q G + S+ G + P ++
Sbjct: 445 GPGKIP------------AQQAGP---GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP 489
Query: 1203 LEQRAGS-------PGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPR 1255
Q+ GS PG+ + +QP P + ++ + S++ P P
Sbjct: 490 PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQP---GSTKPPSQQPGSAKPSAQQPSP 546
Query: 1256 ALPGLDALVAATINLG-----DLPSDSPPDPQPPAASGPPSTVPLPHSSGIHGIALLSEL 1310
A P G P+ SP QPP+ P + PL +++ +
Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELL-------- 598
Query: 1311 ADLAIQRQRSERTVPEEEEDVLA---FNLQHLATLATAW-----SLVEAAGLDSSTAPAQ 1362
L + + + T E + V + FN T W + A G D + P+
Sbjct: 599 --LHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSS 656
Query: 1363 PPTANPCSGPRL-TPRMQILQRKDTWTPKTKPVCPLKAAIDRLDTQEVGMRVRLAELQRR 1421
P P+L T + +P+ + P K A + D +
Sbjct: 657 PQ-------PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKA-----------P 698
Query: 1422 YKEKQRELARLQRKHDHERDESSRSPARRGPGRPRKRKHSSSLPAPRPTGPLPRSDGKKV 1481
+K L + H ++ + P +P K S+P+ + P+ K+
Sbjct: 699 EPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK-EPSVPSEQDKAPVADDKPKQP 757
Query: 1482 KAVRTSLGLLCAELRGGSGGEPAKK-RSKLERSVYAGLQTASVEKAQC------KKSSCQ 1534
K V+ + L+ + P+ K +S+ E L+T S + +Q K S
Sbjct: 758 KMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD 817
Query: 1535 GGLAP---SVAHRVAQLKPKVKSKGLPTGLSSFQQKEATPGGRIREKLSRAKSAKVSGAT 1591
P S + ++ P +SKG QK+ P + +E+ +A++
Sbjct: 818 SKAIPRPASDSKIISHPGPSSESKG---------QKQVDPVQK-KEEPKKAQTKMSPKPD 867
Query: 1592 RHPQPKGHGSRETPRCPAQPSVAASQEAGNGYDSEDCEGL-LG--TEAP------PRE-- 1640
P PKG + PR A +V Q++ + L LG T+AP P+E
Sbjct: 868 AKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETV 927
Query: 1641 AGLLLHTGASVAVLGPSPSSVVKMEANQKAKKKKERQGLLGACRLSSPESEVKIKRRSVK 1700
G L GAS+ + L+ P S+
Sbjct: 928 TGKLFGFGASIF---------------------SQASNLISTAGQPGPHSQ--------- 957
Query: 1701 AKVGTTLERAPG-QRPPGALGKKKAKGKAKGSLRAEPGATPSRDALFNPSRAFACREEGS 1759
+ G +++AP +PP + G K+ G+A + P+++ ++E
Sbjct: 958 SGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPA----------------PAKSIPVKKETK 1001
Query: 1760 QLASERLK-RATRKGTVLQPVLRRKNGAL--SITLATRNAKAIL 1800
A+E+L+ +A + TV + +K + S +L KA+L
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVL 1045
Score = 38.9 bits (89), Expect = 0.067
Identities = 43/170 (25%), Positives = 65/170 (38%), Gaps = 29/170 (17%)
Query: 945 QRKPEDQHLDLEEPAQEKAP-------KSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPP 997
Q KP Q L P+ P +S+ ++ P P P P P PP PP
Sbjct: 2369 QEKPASQ-LPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP---PP 2424
Query: 998 DPKPPASSPTPPPRPSAPCTLNVCPASSPGP----GSRVRSAEEKNGEGQQSTADIITSE 1053
P PP +SP P P T+ P ++ P + + + G T T+
Sbjct: 2425 PPLPPPTSPKPTILPKKKLTV-ASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP 2483
Query: 1054 PDLPPGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLP 1103
P +PP +P S+PS + ++ +P + P P+P LP
Sbjct: 2484 PPVPP---KPS-----SIPSGLVFTHRPEP-----SKPPIAPKPVIPQLP 2520
Score = 37.0 bits (84), Expect = 0.25
Identities = 84/450 (18%), Positives = 145/450 (32%), Gaps = 87/450 (19%)
Query: 954 DLEEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPS 1013
DL + + K P P+ PT G+PS A K PP S P PP PS
Sbjct: 693 DLSKAPEPKKPP----PLVKQPTLHGSPSAKA---KQPP------EADSLSKPAPPKEPS 739
Query: 1014 APCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADII-----TSEPDLPPGYLRPMAGLG 1068
P + P + P K + + T D++ T++PD+P ++ A
Sbjct: 740 VPSEQDKAPVADDKP---------KQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEK 790
Query: 1069 FSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCS-PRSLEEPGLLSGAREAT 1127
+ P + + + + ++ T P ++ P P S + + PG S ++
Sbjct: 791 TTPP--LKTDSAKPSQSFPPTGEKVSPFDSKAI----PRPASDSKIISHPGPSSESKGQK 844
Query: 1128 QDLAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSR 1187
Q P + P+ SP + + + G GQ T
Sbjct: 845 Q---VDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP--------- 892
Query: 1188 EEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGA 1247
+Q P S+ GS + QP ++ + G + S+ +
Sbjct: 893 ---QQSPKPQEQSRRFSLNLGS--ITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 1248 PDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAASGPPSTVPLPHSSGIHGIALL 1307
P + G A + +P QPP + GPP + + I +
Sbjct: 948 TAGQPGPHSQSGPGAPM----------KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVK 997
Query: 1308 SELADLAIQRQRSERTVPEEEEDVLAFNLQHLATLATAWSLVEAAGLDSSTAPAQPPTAN 1367
E + +E+ P+ E +A + + +PP
Sbjct: 998 KE-----TKAPAAEKLEPKAE---------------------QAPTVKRTETEKKPPPIK 1031
Query: 1368 PCSGPRLTPRMQILQRKDTWTPKTKPVCPL 1397
P+ +L K +PK + CPL
Sbjct: 1032 DSKSLTAEPQKAVLPTKLEKSPKPESTCPL 1061
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 62.0 bits (149), Expect = 7e-09
Identities = 85/320 (26%), Positives = 117/320 (36%), Gaps = 36/320 (11%)
Query: 932 ELYALQQQRAAQFQRKPEDQHLDLEEPAQEKAPKSTHKPVALTPTAP-GAPSPAAGPTKL 990
EL L QQRA R + A+ + P+ P A P AP GAP+ AA
Sbjct: 72 ELEKLIQQRAVL--RVSYKGSISYRNAARVQPPRRGATPPA-PPRAPRGAPAAAAAAAP- 127
Query: 991 PPCCHPPDPKPPASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADII 1050
PP PP P P ++ P P A P SPGP + G Q A +
Sbjct: 128 PPTPAPPPPPAPVAAAAPARAPRAAAAAATAP-PSPGPA--------QPGPRAQRAAPLA 178
Query: 1051 TSEP-DLPPGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPC 1109
P P + P AG + P V + P Q AP Q +PPP
Sbjct: 179 APPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQ---------QPPPP 229
Query: 1110 SPRSLEEPGLL--SGAREATQDLAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGG 1167
P+ E G + GA Y G G ++GL E + A
Sbjct: 230 QPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAA------- 282
Query: 1168 PEATGQAHSTQGGAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDEL 1227
A G+ T+ GA + + P + ++ +R G LE E E+ +EDE
Sbjct: 283 --ARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKE-EEEDDDEDED 339
Query: 1228 EEDELGQQSMEDSEEDCGGA 1247
EED++ + S + GA
Sbjct: 340 EEDDVSEGSEVPESDRPAGA 359
Score = 59.7 bits (143), Expect = 4e-08
Identities = 83/343 (24%), Positives = 113/343 (32%), Gaps = 58/343 (16%)
Query: 958 PAQEKAPKSTHKPVALTPTAPGAP---SPAAGPTKLPPCCHPPDPKPPASSPT--PPPRP 1012
PAQ P+A P AP AP +P AGP + PP P A P PPP+P
Sbjct: 164 PAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPP------PAVAAREPPLPPPPQP 217
Query: 1013 SAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLP 1072
AP P P P + S +++ YL G G L
Sbjct: 218 PAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVR--------YLGGSGGAGGRLT 269
Query: 1073 SDVHSSNLEDPET----MQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQ 1128
LE+ ++ T GA P R PG PP +
Sbjct: 270 RGRVQGLLEEEAAARGRLERTRLGALALP-RGDRPGRAPPAA------------------ 310
Query: 1129 DLAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSRE 1188
+A P ++RG + + + E E + E + + A + +
Sbjct: 311 --SARPSRSKRGGEERVLEKEEEEDDDEDED----EEDDVSEGSEVPESDRPAGAQHHQL 364
Query: 1189 EGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAP 1248
GE+GP S A +V E P +DEG PAP + + + E P
Sbjct: 365 NGERGPQS-AKERVKEWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGP 423
Query: 1249 DNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAASGPPS 1291
D+ P PG AL A D P PP PS
Sbjct: 424 DSPSPVPLPPGKPALPGA---------DGTPFGCPPGRKEKPS 457
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 61.6 bits (148), Expect = 1e-08
Identities = 203/963 (21%), Positives = 305/963 (31%), Gaps = 148/963 (15%)
Query: 976 TAPGAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSA 1035
T G P+P P+ P P P +SSP+PPP P P P + P P +
Sbjct: 179 TGDGGPAPPPAPSS---ASSSPSPSPSSSSPSPPPPPPPPA-----PPAPPAPRFDIYDP 230
Query: 1036 EEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQP 1095
E S P P P G + S + + E+ E + +
Sbjct: 231 FHPTDEAY--------SPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEE 282
Query: 1096 EPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERGPQGKAADPSPLEGLQ 1155
+ EE GL ++ LA Y Q D SP Q
Sbjct: 283 DEE----------------EEEGLSQSISRISETLAGI-YDDNSLSQDFPGDESPRPDAQ 325
Query: 1156 ELQCAALLEAGGPEATGQAHSTQG-----------GAREERSREEGEQGPSSGASSQVLE 1204
Q P Q ST+ G E RE A L
Sbjct: 326 PTQ-----PTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALP 380
Query: 1205 QRAGSPGALE-DEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDAL 1263
PG E +EGE PEE E L P S P A P L
Sbjct: 381 PPLLPPGDSEIEEGEIVQPEE----EPRLALSLFRPGGRAARPTPAASATPTAQP-LPQP 435
Query: 1264 VAATINLGD----LPSDSPPDPQPPAASGPPSTVPLPHSSGIHGIALLSELADLAIQR-- 1317
A GD L ++S + G P+ P S G+ L ++ +R
Sbjct: 436 PAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKILTQRRERYR 495
Query: 1318 QRSERTVPEEEEDVLA---FNLQHLATLATAWSLVEAAGLDSSTAPAQPPTANPCSGPRL 1374
QRS P A + + EAA S T PA P A+P +
Sbjct: 496 QRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKH 555
Query: 1375 TPR--------MQILQRKDTWTPKTKPVCPLKAAIDRLDTQEVGMRVRLAELQRRYKEKQ 1426
R +R+ +++ + DR + G R + +RR + +
Sbjct: 556 RSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDR---RRGGSRRSRSREKRRRRRRS 612
Query: 1427 RELARLQRKHDHERDESSRSPARRGPGRPRKRKHSSS--------------LPAPRPTGP 1472
R E R R G G +K+K S S PAP P+G
Sbjct: 613 ASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGS 672
Query: 1473 LPRSDGKKVKAVRTSLGLLCAELRGGSGGEPAKKRSKLERSVYAGLQTASVEKAQCKKSS 1532
TS G + RG P + + ++A +T +V + KS
Sbjct: 673 -------------TSCGDRDSRRRGAV---PPSIQDLTDHDLFAIKRTITVGRLD--KSD 714
Query: 1533 CQG-GLAPSVAHRVAQLKPKVKSKGLPTGLSSFQQKEATPGGRIREKLSRAKSAK---VS 1588
+G AP+ + + L G G S Q+ G SR K ++ +
Sbjct: 715 PRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALD 774
Query: 1589 GATR-----------HPQPKGHGSRET-PRCPAQPSVAASQEAGNGYDSEDCEGLLGTEA 1636
G R K +E+ P P S +G+ S C
Sbjct: 775 GGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCSSR--KVK 832
Query: 1637 PPREAGLLLHTGASVAVLGPSPSSVVKMEANQKAKKKKERQGLLGACRLSSPESEVKIKR 1696
+ +L+ G S +S K + +E + +P K
Sbjct: 833 LQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAP 892
Query: 1697 RSVKAKVGTTLERAPGQRPPGALGKKKAKGKAKGSLRAEPGATPSRDAL-FNPSRAFACR 1755
S K K +A ++ G GK K K + +R+ G+ S + S+A +C
Sbjct: 893 GSTKPKKTKVKAKAGAKKTKGTKGKTKPS-KTRKKVRSGGGSGGSGGQVSLKKSKADSCS 951
Query: 1756 EEGSQLASERL-----KRATRKGTVLQPVLRRKNGALSITLATRNAKAILGKGRKLSKVK 1810
+ +E +RA + + P AL+ T ++ K ++S +
Sbjct: 952 QAAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSC---KTPEVSFLP 1008
Query: 1811 HKAGKQGKGRAVSRLLESFAVEEDFEFDDNSSFSEEEEDEEEEEEDSGPLSAEQSAALAR 1870
+A ++ R EE+ E ++ EEEE+EEEEE+ +A +AA A
Sbjct: 1009 EEATEEAGVRG--------GAEEEEEEEE-----EEEEEEEEEEQQPATTTATSTAAAAP 1055
Query: 1871 SCA 1873
S A
Sbjct: 1056 STA 1058
Score = 32.0 bits (71), Expect = 8.2
Identities = 78/355 (21%), Positives = 114/355 (32%), Gaps = 54/355 (15%)
Query: 978 PGAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPR---PSAPCTLNVCPASSPGPGSRVRS 1034
P P P A P PP P +S TP A V +
Sbjct: 974 PSTPPPKAAPP--PPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEEEE 1031
Query: 1035 AEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQ 1094
EE+ E QQ TS P P AG S S ED + +
Sbjct: 1032 EEEEEEEEQQPATTTATSTAAAAPS-TAPSAG------STAGDSGAEDGPASRVSQLPTL 1084
Query: 1095 PEPTRTFLPGEPPPCSPRS----------LEEPGLLSGAR-----EATQDLAATPYPTER 1139
P P LP C+ +EE L S A+ +AT + + P
Sbjct: 1085 PPPMPWNLPAGVD-CTTSGVLALTALLFKMEEANLASRAKAQELIQATNQILSHRKP--- 1140
Query: 1140 GPQGKAADPSPLE---GLQELQCAALLEAGGP-EATGQAHSTQGGAREERSREEGEQGPS 1195
P P+P+ GL + LL P G T G + EG
Sbjct: 1141 -PSSLGMTPAPVPTSLGLPPGPSSYLLPGSLPLGGCGSTPPTPTGLAATSDKREGSSSSE 1199
Query: 1196 S-GASSQVLEQRAGSPGALEDE--GEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSH 1252
G + + L++ A+E+ +P ++ ++ ++E + + C +
Sbjct: 1200 GRGDTDKYLKKLHTQERAVEEVKLAIKPYYQKKDITKEEYKDILRKAVHKICHSKSGEIN 1259
Query: 1253 PPRALPGLDALVAATINL-------GDLPSDSPPDPQPPAASGPPST----VPLP 1296
P + + LV A + G P D P P+PP GPP +PLP
Sbjct: 1260 PVK----VSNLVRAYVQRYRYFRKHGRKPGDPPGPPRPPKEPGPPDKGGPGLPLP 1310
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 61.6 bits (148), Expect = 1e-08
Identities = 109/464 (23%), Positives = 155/464 (33%), Gaps = 55/464 (11%)
Query: 850 PGFPASVAG---PVPSVFPLPQDAPTQLVILP------SEPTPHSAPHALADVMDQASLW 900
P PA+ G PV +V P PQ P LP P AP A QA+
Sbjct: 605 PATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATT- 663
Query: 901 PPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLEEPAQ 960
P G + GQ P + +L Q L Q +Q E HL +
Sbjct: 664 PQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVI 723
Query: 961 EKAPKSTHKPVALTPTAPGAP-SPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAPCTLN 1019
AP P TP A GA P A ++ P P P+ PA++P P PS+ +L
Sbjct: 724 VSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPA---PAPQIPAAAPLKGPGPSSSPSL- 779
Query: 1020 VCPASSP-GPGSRVRSAEEKNGEGQ-QSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHS 1077
P +P G + S + S ++ P PP + P +LP
Sbjct: 780 --PHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVI 837
Query: 1078 SNLEDPETMQTTAPGAQPEPTRTFLPGEP-PPCSPRSLEEPGLLSGAREATQDLAATPYP 1136
N + P + P PT PG P PP P+S G L A ++
Sbjct: 838 QN-----QLGVPPPASNPAPT---APGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVA 889
Query: 1137 TERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGEQGPSS 1196
+ + P+P + + P + G S E P
Sbjct: 890 SSSETSSRLPAPTPSD----------FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPP 939
Query: 1197 GASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRA 1256
+ Q++ + P+ L E S + GGAP +
Sbjct: 940 PRTFQMVTTPFPA-----------LPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTS 988
Query: 1257 LPGLDALVAATINLGDLPSDSP------PDPQPPAASGPPSTVP 1294
L L + A+ + G PS +P P P P AA+G P +P
Sbjct: 989 LGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLP 1032
Score = 52.0 bits (123), Expect = 8e-06
Identities = 131/579 (22%), Positives = 174/579 (30%), Gaps = 99/579 (17%)
Query: 838 GLGHPALHQNLPPGFPASVAGPVPSVFPLPQDAPTQLVILPSE-----PTPHSAPHA--- 889
G PAL N+ PA+ G P P P + +L P H P
Sbjct: 413 GFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQF 472
Query: 890 ------LADVMDQASLWPPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQ 943
+ Q S P GG+ A+ H G + + P L Q L
Sbjct: 473 LLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGG-QLIANPILTNQNLAGPLSLGPVLA 531
Query: 944 FQRKPEDQHLDLEEPAQEKAPKSTHKPVALTPTAPGAPSPAAG--PTKLPPCCHPPDPKP 1001
H+ P Q P PV+L AAG PT+ P P
Sbjct: 532 PHSGAHSAHILSAAPIQVGQPALFQMPVSL----------AAGSLPTQSQPAPAGPAATT 581
Query: 1002 PASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYL 1061
T PP SA LN P V+ A G+ + + P PP
Sbjct: 582 VLQGVTLPP--SAVAMLNT-------PDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVS 632
Query: 1062 RPMAGLGFSLPSDVHSSNLEDPE-------TMQTTAPGAQPEPTRTFLPGEPPPCSPRSL 1114
P+ LG P P+ T +PG P + L G+PP +P ++
Sbjct: 633 TPLP-LGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVL-GQPPSATPTAI 690
Query: 1115 EEPGLLSGAREATQDLAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQA 1174
TQD P ER Q P EG A+++ + P A A
Sbjct: 691 -----------LTQDSLQMFLPQERSQQ-----PLSAEGPHLSVPASVIVSAPPPAQDPA 734
Query: 1175 HSTQGGAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQ 1234
+T + G Q P S AS Q P A +G P+ + LG
Sbjct: 735 PATPVA----KGAGLGPQAPDSQASPAPAPQ---IPAAAPLKGPGPSSSPSLPHQAPLGD 787
Query: 1235 Q------------SMEDSEEDCGGAPDNSHP------PRALPGLDALVAATINLGDLPSD 1276
S S P + P P+A P L + LG P
Sbjct: 788 SPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPA 847
Query: 1277 SPPDPQPPAASGP-------PSTVPLPHSSGIHGIALLSELADLAIQRQRSERTVPEEEE 1329
S P P P P P PLP + + + S +A + R P +
Sbjct: 848 SNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD-- 905
Query: 1330 DVLAFNLQHLATLATAWSLVEAAGLDSSTAPAQPPTANP 1368
F LQ + S L PA PP P
Sbjct: 906 ----FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPP 940
Score = 44.3 bits (103), Expect = 0.002
Identities = 89/392 (22%), Positives = 129/392 (32%), Gaps = 27/392 (6%)
Query: 772 LLLQDSKDR-VEFARIHPPSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTRSPSL 830
+L QDS + R P S G PHL + + + P P P P P + L
Sbjct: 690 ILTQDSLQMFLPQERSQQPLSAEG---PHLSVPASVIVSAPPPAQDPAPA-TPVAKGAGL 745
Query: 831 WMGGHSYGLGHPALHQNLPPGFPASVAGPVPSVFP-LPQDAPTQLVILPSEPTPH----- 884
PA +P P + GP PS P LP AP L P P+PH
Sbjct: 746 GPQAPD-SQASPAPAPQIPAAAP--LKGPGPSSSPSLPHQAP--LGDSPHLPSPHPTRPP 800
Query: 885 SAPHALADVMDQASLWPPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQF 944
S P + + + PP++ P + PG + ++ + A Q
Sbjct: 801 SRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQP 860
Query: 945 QRKPEDQHLDLEEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPAS 1004
+P+ Q P + P + H P + T +A + S + P PP+
Sbjct: 861 PLRPQSQ------PPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQ 914
Query: 1005 SPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPG-YLRP 1063
P P P L PA+ P P R ++ +P G L+
Sbjct: 915 GPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQN 974
Query: 1064 MAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGA 1123
AG + P S G P T T P P + P LL
Sbjct: 975 KAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAE 1034
Query: 1124 REATQDLAATPYPTERGPQGKAADPSPLEGLQ 1155
+A A+ PT + ++ P GLQ
Sbjct: 1035 NKA----FASNLPTLNVAKAASSGPGKPSGLQ 1062
Score = 36.2 bits (82), Expect = 0.43
Identities = 82/378 (21%), Positives = 125/378 (33%), Gaps = 58/378 (15%)
Query: 950 DQHLDLEEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASSPTPP 1009
D+ L E+P E S + + ++ G P GP P AS+ PP
Sbjct: 1190 DKQLAKEKP-DEYVSSSRSLGLPIAASSEGHRLPGHGPLS--------SSAPGASTQPPP 1240
Query: 1010 PRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLP-PGYLRP----- 1063
P+ + SP S+ + S A + ++ D P P RP
Sbjct: 1241 HLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTY 1300
Query: 1064 ----MAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGL 1119
GL + + S + + P P T EPPP P G
Sbjct: 1301 EARSRIGLKLKIKQEAGLSKVVHNTALDPVHQ--PPPPPATLKVAEPPPRPPPPPPPTGQ 1358
Query: 1120 LSGAREATQDLAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQG 1179
++G + P ER P G A P L++ + G PE T A +G
Sbjct: 1359 MNGTVD-----HPPPAAPERKPLG-TAPHCPRLPLRKTYRENVGGPGAPEGT-PAGRARG 1411
Query: 1180 GAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMED 1239
G+ + E A+S ++ + A A+EDE Q + E Q D
Sbjct: 1412 GSPAPLPAKVDE------ATSGLIRELA----AVEDELYQRMLKGPPPEPAASAAQGTGD 1461
Query: 1240 SEEDCGGAPDNSHPPRALPGLD-------------------ALVAATINLGDLPSDSPPD 1280
+ + G P P +D + + + +NL P +P
Sbjct: 1462 PDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAP 1521
Query: 1281 PQPPAAS-GPPSTVPLPH 1297
P AAS G P++ P H
Sbjct: 1522 SYPHAASAGTPASPPPLH 1539
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 60.5 bits (145), Expect = 2e-08
Identities = 106/393 (26%), Positives = 132/393 (33%), Gaps = 64/393 (16%)
Query: 790 SSCPGDLAPHLMMQS--GQLGGDPA------PHTHPHPPWLPRTRSPSLWMGGHSYGLGH 841
++ G L H++ S G G PA P P PP R R GG G
Sbjct: 52 AAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPG----GGGPQRPGP 107
Query: 842 PALHQNLPPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPT----PHSAPHALADVMDQA 897
P+ + L P PA P + P P+ + +P+ P AP A A
Sbjct: 108 PSPRRPLVPAGPAP---PAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPA 164
Query: 898 SLWPPMYGGRGPASHMQHPGQLPVYSRP------QLLRQQELYALQQQRAA---QFQRKP 948
+L G GP PG P +P Q L AA
Sbjct: 165 ALAARAGPGPGPGPG---PGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNG 221
Query: 949 EDQHLDLEEPAQEKAPKSTHKPV-ALTPTAPGAPSPAAGPTKLPPCCHPPDPKP-PASSP 1006
L L +PA T V A P AP APSP A P P PP P P PA+
Sbjct: 222 PAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLA 281
Query: 1007 TPPPRPSAPCT----------------LNVCPASSPGPGSRVR-SAEEKNGEGQQSTADI 1049
PP P+ P T PA +P G S + G + A
Sbjct: 282 RPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPG 341
Query: 1050 ITSEPDLPPGYLRPMAG--LGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPP 1107
+ +E P A L S P+ +S + P TMQ GA P P PP
Sbjct: 342 VKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGP-TMQ----GALPSPAAV-----PP 391
Query: 1108 PCSPRSLEEPGLLSGAREATQDLAATPYPTERG 1140
P P +GA TQ L+ TP T G
Sbjct: 392 PAPGTPTGLPKGAAGA--VTQSLSRTPTATTSG 422
Score = 49.3 bits (116), Expect = 5e-05
Identities = 102/423 (24%), Positives = 135/423 (31%), Gaps = 79/423 (18%)
Query: 812 APHTHPHPPWLPRTRSPSLWMGGHSYGLGHPALHQNLPPGFPASVAGPVPSVFPLPQDAP 871
A H H P P R+ + AL ++ G PA AG P+
Sbjct: 37 AAHHHHLAPRTPEVRAAAAG-----------ALGNHVVSGSPAGAAGAGPAA-------- 77
Query: 872 TQLVILPSEPTPHSAPHALADVMDQASLWPPMYGGRGPASHMQHPGQLPVYSRPQLLRQQ 931
P+E P +AP PP R Q PG P R+
Sbjct: 78 ------PAEGAPGAAPEP-----------PPAGRARPGGGGPQRPG-------PPSPRRP 113
Query: 932 ELYALQQQRAAQFQRKPEDQHLDLEEPAQEKAPKSTHKPVALTPT-APGAPSPAAGPTKL 990
+ A AA+ + PE A AP VA P AP P+ AGP L
Sbjct: 114 LVPAGPAPPAAKLRPPPEGS-------AGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAAL 166
Query: 991 PPCCHP---PDPKP-PASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQST 1046
P P P P P P P P A TLN S+ S +A +
Sbjct: 167 AARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLN---GSAALLNSHHAAAPAVSLVNNGPA 223
Query: 1047 ADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEP 1106
A + +P P ++ +G + P + + P AP A P P P
Sbjct: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPS--PPAAPAPAAPAAAPPP--------P 273
Query: 1107 PPCSPRSLEEPGLLSGAREATQDLAATPYPTERGPQGKAADPSP-------LEGLQELQC 1159
PP PG +G A + G G A P+P + G
Sbjct: 274 PPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGA 333
Query: 1160 AALLEAGGPEATGQAHSTQGGAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQ 1219
AA A G +A Q A ++ GP+S A+S V+ GAL
Sbjct: 334 AAAAPAPGVKAESPKRVVQ--AAPPAAQTLAASGPASTAASMVIGPT--MQGALPSPAAV 389
Query: 1220 PAP 1222
P P
Sbjct: 390 PPP 392
Score = 37.4 bits (85), Expect = 0.20
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 11/99 (11%)
Query: 8 PPPHLLSERGSLGHRSAAAAARLAPAGPAAQP-----PAHFQPGKYFPSP------LPMA 56
PPP GS G A A A PAG + QP A PG SP P A
Sbjct: 298 PPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPA 357
Query: 57 SHTASSRLMGSSPASSFMGSFLTSSLGSAASTHPSGPSS 95
+ T ++ S+ AS +G + +L S A+ P P +
Sbjct: 358 AQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT 396
Score = 32.3 bits (72), Expect = 6.3
Identities = 55/212 (25%), Positives = 71/212 (33%), Gaps = 26/212 (12%)
Query: 1090 APGAQPEPTRT--FLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERGP-QGKAA 1146
APGA PEP PG P + PG S R A P R P +G A
Sbjct: 82 APGAAPEPPPAGRARPGGGGP------QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAG 135
Query: 1147 DPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGEQGPSSGASSQVLEQR 1206
+P+ AA A GPE + G +R GP G +
Sbjct: 136 SCAPVP-------AAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGK 188
Query: 1207 AGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDALVAA 1266
PGA + A L ++ S + G A P A PG ++
Sbjct: 189 PAGPGAAQTLNGSAAL----LNSHHAAAPAV--SLVNNGPAALLPLPKPAAPG--TVIQT 240
Query: 1267 TINLGDLPSDSPPDPQPPAASGP--PSTVPLP 1296
+G +P P PPAA P P+ P P
Sbjct: 241 PPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPP 272
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 59.3 bits (142), Expect = 5e-08
Identities = 107/463 (23%), Positives = 142/463 (30%), Gaps = 48/463 (10%)
Query: 853 PASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADVMDQASLWPPMYGGRGPASH 912
PA+ P P P P+ APT + P P + P +L P G PA
Sbjct: 850 PATTHSPTP---PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPA-- 904
Query: 913 MQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLEEPAQEKAPKSTHKPVA 972
P Q P S + + + P + + PA +PK P A
Sbjct: 905 ---PKQAPALS------------MTSSSPKKARATPAPKGI----PASP-SPKGAPTPPA 944
Query: 973 LTPTAP----GAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAPCTLNVCPASSPGP 1028
TP +P PSP PT PP PP PK ++P+P P+ P P P
Sbjct: 945 ATPPSPKGGPATPSPKWAPT--PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPAT 1002
Query: 1029 GSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLED--PETM 1086
S + A S + P P G P A S ++ L P T
Sbjct: 1003 PSP-KGAPTPPAVTPPSPKGSPAATP-FPKGASTPPAATPPSPKGSPAATPLPKGAPTTP 1060
Query: 1087 QTTAPGAQPEPTRTFLPGEPPP--CSPRSLEEPGLLSGAREATQDLAATPYPTERGPQGK 1144
T P + P L G P P +P S + + A AATP P+G
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP----PSPKGG 1116
Query: 1145 AADPSPLEGLQELQCAALLEAGGPEATG--QAHSTQGGAREERSREEGEQGPSSGASSQV 1202
A P P +G A G AT + T A + P GA +
Sbjct: 1117 LATP-PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175
Query: 1203 LEQRAGSPGALEDEGEQPAPEEDELEEDE----LGQQSMEDSEEDCGGAPDNSHPPRALP 1258
G L + AP L S + + P + A P
Sbjct: 1176 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1235
Query: 1259 GLDALVAATINLGDLPSDSPPDPQPPAASGPPSTVPLPHSSGI 1301
P P P P A PP+ P G+
Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL 1278
Score = 58.2 bits (139), Expect = 1e-07
Identities = 125/530 (23%), Positives = 162/530 (30%), Gaps = 102/530 (19%)
Query: 783 FARIHPPSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTRSPSLWMGGHSYGLGHP 842
F + P + P AP L M S P P +P + SP G P
Sbjct: 895 FPKEGPATPAPKQ-APALSMTSSS---PKKARATPAPKGIPASPSPK----------GAP 940
Query: 843 ALHQNLPPGFPASVAGPVPSVFPLPQDA-PTQLVILPSEPTPHSAPHALADVMDQASLWP 901
PP A P P P P A P P+ P+P AP A P
Sbjct: 941 TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAAT-------P 993
Query: 902 PMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLEEPAQE 961
P G GPA+ P P + + AA K P+ +
Sbjct: 994 PSPKG-GPATPSPKGAPTPPAVTPP--------SPKGSPAATPFPKGASTPPAATPPSPK 1044
Query: 962 KAPKSTHKPVALTPTAPGA--PSPAAGPTK-------LPPCCHPPDPKPPASSPTPPPRP 1012
+P +T P PT P A PSP GP PP PP PK ++P+P P
Sbjct: 1045 GSPAATPLPKG-APTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP 1103
Query: 1013 SAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLP 1072
P A+ P P + + K T+ PP P GL P
Sbjct: 1104 MPPA------ATPPSPKGGLATPPHKGAP---------TTPAATPPS---PKGGLATPPP 1145
Query: 1073 SDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPP---PCSPRSLEEPGLLSGAREATQD 1129
T P A P + L PP P +P + A + +
Sbjct: 1146 KGA------------PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKG 1193
Query: 1130 LAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREE 1189
TP T P+G A PSP +G A G AT S +G +
Sbjct: 1194 APTTPAATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGLAT---PSPKGAPTTPAATPP 1249
Query: 1190 GEQG-----PSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDC 1244
+G P GA + G L + AP + +
Sbjct: 1250 SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV------------TPPSP 1297
Query: 1245 GGAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAASGPPSTVP 1294
G P S PP+ P A + P SP P P A PP+ P
Sbjct: 1298 KGGPATS-PPKGAPTPPAATPPS------PKGSPGTPPPKGAPTPPAVTP 1340
Score = 58.2 bits (139), Expect = 1e-07
Identities = 98/388 (25%), Positives = 141/388 (36%), Gaps = 41/388 (10%)
Query: 788 PPSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTRSPSLWMGGHSYGLGHPALHQN 847
PP++ P L L + +PA T P P P T P G + P +
Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPK---GAPTPPAATPPSPKG 1322
Query: 848 LPPGFPASVAGPVPSVF--PLPQDAPTQLVILPSEPTPHSAPHALADVMDQASLWPPMYG 905
PG P P P P P+ PT PS + P + A+ P +
Sbjct: 1323 -SPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT--PSHK 1379
Query: 906 GRGPASHMQHPGQLPVYSRPQL-LRQQELYALQQQRAAQFQRKPEDQHL----DLEEPAQ 960
G GPA P + P P+ + L ++A E DL PA
Sbjct: 1380 G-GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438
Query: 961 -----EKAPK-STHKPVALTPTAPGAPS-PAAGPTKLPPCCHPPDPKPPASSPTPPPRPS 1013
+KAP S K TP++ G P+ PA P P PP PK A+S +P P+
Sbjct: 1439 TPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP---PSPKEPPAPKQVATSSSPKKAPA 1495
Query: 1014 APCTLN--VCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGL---G 1068
P + PA P V + + TA +++ + P L P L
Sbjct: 1496 TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK---TPATLAPKEALIPPA 1552
Query: 1069 FSLPSDVHSSNL----EDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLS--G 1122
++PS + + E P T + + P T + G P SP+ L P ++
Sbjct: 1553 MTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAP---SPKELLIPPAVTSPS 1609
Query: 1123 AREATQDLAATPYPTERGPQGKAADPSP 1150
+EA A TP E+GP A +P
Sbjct: 1610 PKEAPTPPAVTPPSPEKGPATPAPKGTP 1637
Score = 50.8 bits (120), Expect = 2e-05
Identities = 185/841 (21%), Positives = 265/841 (31%), Gaps = 139/841 (16%)
Query: 963 APKSTHKPVALTPTAP----GAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAPCTL 1018
+PK A TP +P PSP PT P PP PK ++P+P P+ P
Sbjct: 1190 SPKGAPTTPAATPPSPKGGLATPSPKGAPTT--PAATPPSPKGGLATPSPKGAPTTPA-- 1245
Query: 1019 NVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRP----MAGLGFSLPSD 1074
A+ P P + K + + P L G P P
Sbjct: 1246 ----ATPPSPKGGPATPPPKGAPTPPA-----ATPPSLKGGLATPPHKGAPNPAVVTPPS 1296
Query: 1075 VHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATP 1134
P T P A P P+ PG PPP + P + + + T L AT
Sbjct: 1297 PKGGPATSPPKGAPTPPAATP-PSPKGSPGTPPPKGAPT--PPAVTPPSPKGTPTLPATT 1353
Query: 1135 YPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGEQGP 1194
++ GP PS EG A P G T + + + P
Sbjct: 1354 PSSKGGP----TTPSSKEG-------PTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402
Query: 1195 SSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPP 1254
+S A + ++A P P + +L + S++ AP S P
Sbjct: 1403 TSPAVIPLSPKKA--PATPVTREGAATPSKGDLTPPAVTPVSLKK-------APATSAPK 1453
Query: 1255 RALPGLDALVAATINLGD--LPSDSPPDPQPPAASGPPSTVPLPHSSGIHGIALLSELAD 1312
A + GD LP+ +PP P+ P A +T P + + +
Sbjct: 1454 GG-------PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP 1506
Query: 1313 LAIQRQRSE-RTVPEEEEDVLAFNLQHLATLATAWSLVEAAGLDSSTAPAQPPTANPCSG 1371
I E P D +A TA L + + A P A
Sbjct: 1507 AVIPSSPKEVPATPSSRRDPIA---------PTATLLSKKTPATLAPKEALIPPAMTVPS 1557
Query: 1372 PRLTPRMQILQRKDTWTPKTKPVCPLKAAIDRLDTQEVGMRVRLAELQRRYKEKQRELAR 1431
P+ TP + TPK P P ++E + + +EL
Sbjct: 1558 PKKTPAIP--------TPKEAPATP--------SSKEASSPPAVTPSTYKGAPSPKELLI 1601
Query: 1432 LQRKHDHERDESSRSPARRGPGRPRKRKHSSSLPAPRPTGPLPRSDGKKVKAVRTS-LGL 1490
E+ PA P P K + PAP+ T P +K TS +
Sbjct: 1602 PPAVTSPSPKEAPTPPAVTPPS-PEK---GPATPAPKGTPTSPPVTPSSLKDSPTSPASV 1657
Query: 1491 LC---AELRGGSGGEPAKKRSKLERSVYAG-------LQTASVEKA-QCKKSSC------ 1533
C A + S G PAKK + V + TA K Q KKSS
Sbjct: 1658 TCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPIC 1717
Query: 1534 ------QGGLAPSVAHRVAQLKPKVK-----SKG-----LPTG-LSSFQQKEATP--GGR 1574
G P A L P K +KG P G L+ + K +TP
Sbjct: 1718 PDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA 1777
Query: 1575 IREKLSRAKSAKVSGATRHPQPKGHGSRETPR-------CPAQPSVAASQEAGNGYDSED 1627
+ L + +SA VS A P P P+ P + + +++
Sbjct: 1778 FEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE 1837
Query: 1628 CEGLLGTEAPPREAGLLLHTGASVAVLGPSPSS----VVKMEANQKAKKKKERQGLLGAC 1683
E L P G+ SV V P+P S V A Q K + G
Sbjct: 1838 DELLPLIPPEPISGGVPFQ---SVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDS 1894
Query: 1684 RLSSPESE----VKIKRRSVKAKVGTTLERAPGQRPPGALGKKKA-KGKAKGSLRAEPGA 1738
S PE E + + + ++ P + + +KKA K +K LR G
Sbjct: 1895 DESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGV 1954
Query: 1739 T 1739
T
Sbjct: 1955 T 1955
Score = 43.9 bits (102), Expect = 0.002
Identities = 82/374 (21%), Positives = 121/374 (32%), Gaps = 64/374 (17%)
Query: 958 PAQEKAPKSTHKPVALTPTA----PGAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPS 1013
P + T + L PTA P APSP L P+ SP+ PP +
Sbjct: 685 PKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGT 744
Query: 1014 APCTLNVCPASSPGPGSRVRSA------EEKNGEGQQSTADIITSEPDLP--------PG 1059
P T V S + V S+ E+ S+ +T D P P
Sbjct: 745 PPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQ 804
Query: 1060 YLRPMAGLGFSLPSDVHSSNLEDPET---------MQTTAPGAQPEPTRTFLP------G 1104
RP G + P D NL P + + G++ P T P G
Sbjct: 805 TKRPPTKKGSAGP-DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKG 863
Query: 1105 EPPPCSPRSLEEPGLLSGAREA-TQDLAATPYPTERGPQGKAADPSPLEGLQELQCAALL 1163
P P + L G+ +E T + P+P E GP A +P +
Sbjct: 864 APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKE-GPATPAPKQAPALSMTSSSPKKAR 922
Query: 1164 EAGGPEATGQAHSTQGGAREERSREEGEQ-GPSSGASSQVLEQRAGSPGALEDEGEQPAP 1222
P+ + S +G + + GP++ + A +P + + P+P
Sbjct: 923 ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP 982
Query: 1223 EEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQ 1282
+ GAP PP A P AT + P +PP
Sbjct: 983 K----------------------GAPT---PPAATPPSPKGGPATPSPKGAP--TPPAVT 1015
Query: 1283 PPAASGPPSTVPLP 1296
PP+ G P+ P P
Sbjct: 1016 PPSPKGSPAATPFP 1029
Score = 41.6 bits (96), Expect = 0.010
Identities = 73/312 (23%), Positives = 104/312 (33%), Gaps = 76/312 (24%)
Query: 865 PLPQDAPTQLVILPSEP-----TPHS-----APHALADVMDQASLWPPMYGGRGPASHMQ 914
P P APT ++PS P TP S AP A + P PA +
Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVP 1556
Query: 915 HPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLEEPAQEKAPKSTHKPVALT 974
P + P P+ E PA + +++ P
Sbjct: 1557 SPKKTPAIPTPK-----------------------------EAPATPSSKEASSPPAVTP 1587
Query: 975 PTAPGAPSPAAGPTKLPPCCHPPDPK----PPASSPTPPPRPSAPCTLNVCPASSPGPGS 1030
T GAPSP +PP P PK PPA +P P + A P S P S
Sbjct: 1588 STYKGAPSPKE--LLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPS 1645
Query: 1031 RVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLED------PE 1084
++ + S A + G P A G LP+ + L++ PE
Sbjct: 1646 SLK-------DSPTSPASVTCK-----MGATVPQASKG--LPAKKGPTALKEVLVAPAPE 1691
Query: 1085 -TMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPY-----PTE 1138
T TAP + T+ PP C +P +G++ +A P +
Sbjct: 1692 STPIITAPTRKGPQTKKSSATSPPIC-----PDPSAKNGSKGPLSTVAPAPLLPVQKDSS 1746
Query: 1139 RGPQGKAADPSP 1150
+ +GK A SP
Sbjct: 1747 KTAKGKDASHSP 1758
Score = 40.4 bits (93), Expect = 0.023
Identities = 81/349 (23%), Positives = 102/349 (29%), Gaps = 90/349 (25%)
Query: 963 APKSTHKPVALTPTAP-GAPSPAAGPTKLPPCCHPPDPK----PPASSPTP-----PPRP 1012
+P +TH P TP +P GAP+P+A P PK PP +PTP P
Sbjct: 849 SPATTHSP---TPPSPKGAPTPSA--------VTPLSPKGVTLPPKETPTPSVVNLPFPK 897
Query: 1013 SAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLP 1072
P T PA P + S+ K + I S P G P A + P
Sbjct: 898 EGPAT----PAPKQAPALSMTSSSPKKARATPAPKGIPASPS--PKGAPTPPAA---TPP 948
Query: 1073 SDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAA 1132
S P+ T P P G P SP+ P
Sbjct: 949 SPKGGPATPSPKWAPTPPAATPPSPK-----GGPATPSPKGAPTP--------------- 988
Query: 1133 TPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGEQ 1192
P T P+G A PSP G P + G+ +G
Sbjct: 989 -PAATPPSPKGGPATPSP--------------KGAPTPPAVTPPSPKGSPAATPFPKGAS 1033
Query: 1193 GPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSH 1252
P + GSP A P L + G + GAP
Sbjct: 1034 TPPAATPPSP----KGSPAATPLPKGAPTTPAATLPSPKGGPAT-----PSLKGAPT--- 1081
Query: 1253 PPRALPGLDALVAATINLGDLPSDSPPDPQPPAASGPPSTVPLPHSSGI 1301
PP A P P P P P A PP+ P G+
Sbjct: 1082 PPAATP-------------PSPKGGPATPSPKGAPMPPAATPPSPKGGL 1117
Score = 32.0 bits (71), Expect = 8.2
Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 5/77 (6%)
Query: 958 PAQEKAPKSTHKPVALTPTAPGAPSPAA----GPTKLPPCCHPPDPKPPASSPTPPPRPS 1013
PA E+ A+ P + AA GPT PPC P P +++ P PS
Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS 69
Query: 1014 APCTLNVCPASSPGPGS 1030
P T+ P P P S
Sbjct: 70 -PSTIASTPLEVPFPQS 85
Score = 32.0 bits (71), Expect = 8.2
Identities = 108/470 (22%), Positives = 165/470 (35%), Gaps = 55/470 (11%)
Query: 859 PVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADVMDQASLWPPMYGGRGPASHMQHPGQ 918
P+ + P+ T LV+ + T +AP +V S PPM GP S+++
Sbjct: 426 PLVAQMPVSSVGTTPLVVT-NPCTIAAAPTTTFEVATCVS--PPM--SSGPISNIEPTSP 480
Query: 919 LPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHL-DLEEPAQEKAPKSTHKPVALTPT- 976
+ P ++ R P+ + L +L K P T K + P
Sbjct: 481 AALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFP--TQKDLQTVPAS 538
Query: 977 ---APGAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAP-------CTLNVCPASSP 1026
AP +P+ A TK P P P +SP+ S+P TL P
Sbjct: 539 LEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEP 598
Query: 1027 GPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDPE-- 1084
P + S+ + G S+A +I ++ P P+ P+ V + LE +
Sbjct: 599 LPIGKPASS-MTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPT-VAAFPLESADPA 656
Query: 1085 -TMQTTAPGAQPEPTRT--FLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERGP 1141
TTA G T FL G + G L+ A+ P P
Sbjct: 657 GVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTL--PLVPTASENCPVAPSP 714
Query: 1142 QGKAADPSPL----EGLQELQCAALLEAGGPEAT----GQAHSTQGG--AREERSREEGE 1191
Q A + L E + + +L AG P T G +H++ A + +
Sbjct: 715 QNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTED 774
Query: 1192 QGPSSGASSQ-VLEQRAGSPGAL----EDEGEQPAPEEDELEED-ELGQQSMEDSEEDCG 1245
G S+ ASS+ L A SP L + ++P ++ D +G S S +
Sbjct: 775 SGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEAS 834
Query: 1246 GAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAASGPPSTVPL 1295
P+NS + G A T SP P P A P + PL
Sbjct: 835 FLPENS---LSFQGSKDSPATT--------HSPTPPSPKGAPTPSAVTPL 873
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 58.9 bits (141), Expect = 6e-08
Identities = 134/516 (25%), Positives = 175/516 (33%), Gaps = 109/516 (21%)
Query: 817 PHPPWLPRTRSPSLWMGGHSYGLGHPALHQNLPPG-----FPASVAGPVPSVFPLPQDAP 871
P PP SP+LW ++ P L +L P FPAS G F Q AP
Sbjct: 2125 PSPPHPIPMGSPTLWPETEAHV--SPPLDSHLGPARPSLDFPASAFG-----FSSLQPAP 2177
Query: 872 TQLVILPSEPTPHSAP-HALADVMDQASLWPPMYGGRGPASHMQHPGQLPVYSRPQLLRQ 930
QL PS P SAP +LA D+A P GP + +H L V P L
Sbjct: 2178 PQL---PSPAEPRSAPCGSLAFSGDRALALAP-----GPPTRTRHDEYLEVTKAPSLDSS 2229
Query: 931 -QELYALQQQRAAQFQRKPEDQHLDLEEPAQEKAPKSTHKPVA--LTPTAPGAPSPAAG- 986
+L + A P L E + +A VA +P+ A +
Sbjct: 2230 LPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGEL 2289
Query: 987 PTKLPPCCH------PPDPKPPASSPTP-PPRPSAP---------CTLNVCPASSPGPGS 1030
+ P H P P PPAS P PS P C L A++ P
Sbjct: 2290 DPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEAATEKPSP 2349
Query: 1031 RVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTA 1090
+E+ G T+ P+ PPG P+ + N E+
Sbjct: 2350 FQVPSEDCAANGPTETS------PN-PPG------------PAPAKAEN-EEAAACPAWE 2389
Query: 1091 PGAQPEPTR------TFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERGPQGK 1144
GA PE T L E P C P SG ++ A+P E GPQG
Sbjct: 2390 RGAWPEGAERSSRPDTLLSPEQPVC-------PAGGSGGPPSS----ASP-EVEAGPQGC 2437
Query: 1145 AADPSPLEGLQELQCAALLEAGGPEATGQAHSTQ-----GGAREERSREEGEQGPSSGAS 1199
A +P P G EL + L P + ST+ G R G G +
Sbjct: 2438 ATEPRPHRG--ELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVT 2495
Query: 1200 SQVLEQRAGSPGALEDEGEQPAPEEDELEE--DELGQQSMEDSE---EDCGGAPDNSHPP 1254
+ A G+ + + + P PE +E E S ED + D G +H P
Sbjct: 2496 DETPPTSASDSGSSQSDSDVP-PETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHP 2554
Query: 1255 RALPGLDALVAATINLGDLPSDSPPDPQPPAASGPP 1290
R PG D PP PQP PP
Sbjct: 2555 R--PG---------------HDPPPLPQPDPRPSPP 2573
Score = 50.4 bits (119), Expect = 2e-05
Identities = 148/628 (23%), Positives = 207/628 (32%), Gaps = 122/628 (19%)
Query: 760 LCDDRLGLASRELLLQDSKDRVEFARIHPPSSCPGDLAPHLMMQSGQLGGDPAPHTHPH- 818
L + +GL E +D R F I PP+S P + + GQ P P PH
Sbjct: 1773 LAESPVGLPPEE---EDKLTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHM 1829
Query: 819 -------------PPWLPRTRSPSLWMGGHSYGLGHPALHQNLPPGFPASVAGPVPSVFP 865
PPW+P+ R + G PA + P F A SV
Sbjct: 1830 KNEPTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTA-EYDSVVA 1888
Query: 866 LPQDAPTQLVILPSEPTPHSAPHALADVMDQASLWPP---MYGGRGPASHMQHPGQLPVY 922
Q+ +L P P A + ++ P + + P + H P
Sbjct: 1889 AVQEGAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQ 1948
Query: 923 SRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLEEPA----------------------- 959
+ P+ Q+E +R+ Q+ E L PA
Sbjct: 1949 TEPE---QREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEA 2005
Query: 960 -------QEKAPKSTHKPVALTPTAPGAPSPA-AGPTKLPPCCHP-PDPKPPASSPTPPP 1010
EK S P +L P A AGPT +PP P P +P + P PP
Sbjct: 2006 AAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAGPT-VPPRPEPGPSMEPSLTPPAVPP 2064
Query: 1011 R-------PSAPCTLNVCPAS----SPGPGSRVRS--------AEEKNGEGQQSTADIIT 1051
R PS P N+ S SP P RS +E + G +Q + +
Sbjct: 2065 RAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQS 2124
Query: 1052 SEP--DLPPG--YLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPG---AQPEPTRTFLPG 1104
P +P G L P S P D H +A G QP P P
Sbjct: 2125 PSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQPAP-----PQ 2179
Query: 1105 EPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERGPQGKAADPSPLEGLQELQCAALLE 1164
P P PRS L A + LA P P R + + + L ++L +
Sbjct: 2180 LPSPAEPRSAPCGSL---AFSGDRALALAPGPPTRTRHDEYLEVTKAPSLD----SSLPQ 2232
Query: 1165 AGGPEATGQAHSTQGGAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEE 1224
P + G + + EG SS A++ V+ A E P+ E
Sbjct: 2233 LPSPSSPGAPLLSNLPRPASPALSEGS---SSEATTPVISSVA--------ERFSPSLEA 2281
Query: 1225 DELEEDEL--GQQSMEDSEED---CGGAPDNS-----HPPRALPG--LDALVAATINLGD 1272
E E EL G + S D AP S P +LPG D ++ + +
Sbjct: 2282 AEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSE 2341
Query: 1273 LPSDSPPDPQPP----AASGPPSTVPLP 1296
++ P Q P AA+GP T P P
Sbjct: 2342 AATEKPSPFQVPSEDCAANGPTETSPNP 2369
Score = 39.3 bits (90), Expect = 0.051
Identities = 178/761 (23%), Positives = 252/761 (33%), Gaps = 149/761 (19%)
Query: 788 PPSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTRSPSLWMGGHSYGLGHPALHQN 847
PP GD P L + G + + P P++ L +
Sbjct: 1988 PPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKS------------------LQSD 2029
Query: 848 LPPGFPASVAGPV--------PSVFP--LPQDAPTQLVILPSEPTPHSAPHALADVMDQA 897
P A++AGP PS+ P P P + IL P+P + L+ D+
Sbjct: 2030 TPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRR 2089
Query: 898 SLWPPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPE-----DQH 952
S P GR +L +R Q ++ AQ P
Sbjct: 2090 SP-SPKESGRSHWDDSTSDSELEKGAREQ-----------PEKEAQSPSPPHPIPMGSPT 2137
Query: 953 LDLEEPAQEKAPKSTHKPVALTPTAPGAPSPAA--GPTKLPPCCHPPDPKPPASSPTPPP 1010
L E A P +H L P P PA+ G + L P P P+P
Sbjct: 2138 LWPETEAHVSPPLDSH----LGPARPSLDFPASAFGFSSLQPA--------PPQLPSPAE 2185
Query: 1011 RPSAPC-----TLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMA 1065
SAPC + + A +PGP +R R E S + +S P LP P A
Sbjct: 2186 PRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPS---LDSSLPQLPSPS-SPGA 2241
Query: 1066 GLGFSLPSDVHSSNLEDPETMQTTAP-------------GAQPEPTRTFLPGEPPPCSPR 1112
L +LP S L + + + T P A + + PG P +
Sbjct: 2242 PLLSNLPRPA-SPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGELDPGMEP--AAH 2298
Query: 1113 SLEEPGLLSGAREATQDLAATPYPTERGPQG-------------KAADPSPLEGLQELQC 1159
SL + LS A A+ DLA P P+ G G PSP + E C
Sbjct: 2299 SLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQVPSE-DC 2357
Query: 1160 AALLEAGGPEATGQAHSTQGGAREERSREEGEQGPS--SGASSQVLEQRAGSPGALEDE- 1216
A A GP T + + G A + EE P+ GA + E+ + L E
Sbjct: 2358 A----ANGPTET--SPNPPGPAPAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQ 2411
Query: 1217 -----GEQPAPEEDELEEDELGQQSMEDSEEDCGG--APDNSHPPRALPGLDALVAATIN 1269
G P E E G Q G +P +PP P +D +T
Sbjct: 2412 PVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLP-PSIDDRDLSTEE 2470
Query: 1270 LGDLPSDSPPDPQPPAASGPPSTV---PLPHSSGIHGIALLSELADLAIQRQRSERTVPE 1326
+ + P +G P V P S+ G +S+ VP
Sbjct: 2471 VRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSG-------------SSQSDSDVPP 2517
Query: 1327 EEEDVLAFNLQHLATLAT----AWSLVEAAGLDSST---APAQPPTANPCSGPRLTPRMQ 1379
E E+ + + A L + + V+ AG S T P P P PR +P
Sbjct: 2518 ETEECPSITAE--AALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSP--- 2572
Query: 1380 ILQRKDTWTPKTKPVCPLKAAIDRL-DTQEVGMRV-RLAELQRRYKEKQRELARLQRKHD 1437
R D + + ++RL + ++V RV R A + + R L L+ K
Sbjct: 2573 --PRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRL-DLRGKRS 2629
Query: 1438 HERDESSRSPARRGPGRPRKRKHSSSLPAPRPTGPLPRSDG 1478
+ A R P RPR S PA G P S G
Sbjct: 2630 PTPGKGPADRASRAPPRPRSTT-SQVTPAEEKDGHSPMSKG 2669
Score = 35.4 bits (80), Expect = 0.74
Identities = 57/170 (33%), Positives = 68/170 (40%), Gaps = 25/170 (14%)
Query: 1156 ELQCAALLEAGGPEATGQAHSTQGGARE-ERSREEGEQG----PSSGASSQV--LEQRAG 1208
E Q A L A E TG++ SR E QG PS+G S LE+ G
Sbjct: 847 EDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTSSLEEDKG 906
Query: 1209 --SP--------GALEDEGE---QPAPEEDELEEDELGQQSMEDSEEDCG--GAPDNSHP 1253
SP G E GE + E +EE+E ++E SE+ C G P S P
Sbjct: 907 FKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCSQYGTPVFSAP 966
Query: 1254 PRAL-PGLDALVAATINLGDLPSDSPPDPQPPAASGPPSTVPLP-HSSGI 1301
AL PG AL A P DS P SGPPS P H S +
Sbjct: 967 GHALHPGEPALGEAEERCLS-PDDSTVKMASPPPSGPPSATHTPFHQSPV 1015
Score = 32.0 bits (71), Expect = 8.2
Identities = 42/160 (26%), Positives = 66/160 (41%), Gaps = 11/160 (6%)
Query: 1703 VGTTLERAPGQRPPGALGKK-KAKGKAKGSLRAEPGATPSRDALFNPSRAFACREEGSQL 1761
V T + A G P K K + +K SL+A S+ A +E S+L
Sbjct: 293 VATQKDLASGAVPTNLKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSEL 352
Query: 1762 ASERLKRATRKGTVLQPVLRRKNGALSITLATRNAKAILGKGRKLSKVKHKAGKQGKGRA 1821
A E K T K + A + T +++A+ + RKL +K K GK+
Sbjct: 353 AKELAK--TEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKL--IKDKVGKKHLKEK 408
Query: 1822 VSRLLESFAVE------EDFEFDDNSSFSEEEEDEEEEEE 1855
+S+L E E E E + EE++D ++EE+
Sbjct: 409 ISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEK 448
>gi|148612879 polyhomeotic like 3 [Homo sapiens]
Length = 995
Score = 58.9 bits (141), Expect = 6e-08
Identities = 98/421 (23%), Positives = 152/421 (36%), Gaps = 85/421 (20%)
Query: 901 PPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQ---FQRKPEDQHLDLEE 957
P Y P S ++H Q+P++S P + +L QQQ+ Q Q +D
Sbjct: 306 PASYSPIQPHSLIKHQ-QIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDP-----P 359
Query: 958 PAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPAS-------SPTPPP 1010
P+Q P H L P A S P + P P S SP PP
Sbjct: 360 PSQHCIPLQNH---GLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPH 416
Query: 1011 RPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFS 1070
PS T+ + P + P V SA + QQSTA+ + +
Sbjct: 417 SPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQA------------------ 458
Query: 1071 LPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPG--LLSGAREATQ 1128
T Q P P P + P +L PG ++S + +
Sbjct: 459 --------------TAQLNLPSHLPLPASPVV--HIGPVQQSALVSPGQQIVSPSHQQYS 502
Query: 1129 DLAATPYPTERGPQGKAADPS-----PLEGLQELQCAALLEAGGPEATGQAHSTQGGARE 1183
L ++P P PQ + P+ PL+ +Q LQ PE +QG
Sbjct: 503 SLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQ-------PEIL-----SQGQVLV 550
Query: 1184 ERSREEGEQGPSSGASSQVLEQRAGSPG--ALEDEGEQPAPEEDEL--EEDELGQQSMED 1239
+ + E+ P++ A Q+ Q P A+ + + PAP + + + +++ ++ M +
Sbjct: 551 QNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPE 610
Query: 1240 SEEDCGGAPDNSHPPRALPGLDALVAATINLG-DLPSDSPPDPQ---PPAASGPPSTVPL 1295
++C PP P A T+ G DL S+ P Q P AS S +
Sbjct: 611 ESDECVRMDRTPPPPTLSP-----AAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKS 665
Query: 1296 P 1296
P
Sbjct: 666 P 666
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 58.5 bits (140), Expect = 8e-08
Identities = 97/396 (24%), Positives = 136/396 (34%), Gaps = 77/396 (19%)
Query: 788 PPSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTRSPSLWMGGHSYGLGHPALHQN 847
PP PG L PAP P LP+ +P + H Q+
Sbjct: 716 PPPPTPGSAMAQLK---------PAPCA----PSLPQFSAPPPPLKIHQV--------QH 754
Query: 848 LPPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADVMDQA---SLWPPMY 904
+ P + P P PLP AP + ++ PT + +A V+ QA + PP+
Sbjct: 755 ITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPT---STKTVAPVVTQAAPPTPTPPVP 811
Query: 905 GGRG----PASHM-QHPGQLPVYSRPQLLRQQELY-------------ALQQQRAAQFQR 946
+ PAS++ P PV P L +Q+ + ++ +Q A+QF
Sbjct: 812 PAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPP 871
Query: 947 KPEDQHLDLEEPAQEKAPKSTHKPVALTPTAPGA--PSPAAGPTKLP---PCCHPPDPK- 1000
P PA E P P + P +P A P P+ +P P PP P+
Sbjct: 872 PP-------TPPAMESQPLKP-VPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPES 923
Query: 1001 -----PPASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPD 1055
PP SP P P P P T + P S PG + G+ P
Sbjct: 924 SLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGK----------KPPP 973
Query: 1056 LPPGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLE 1115
P + G P S D + T P P++ LP P P L
Sbjct: 974 TPQRNSSIKSSSGAEHPEPKRPS--VDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLN 1031
Query: 1116 EPGL-LSGAREATQDLAATPYPTERGPQGKAADPSP 1150
G+ L G + A P + RG PSP
Sbjct: 1032 LSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSP 1067
Score = 57.4 bits (137), Expect = 2e-07
Identities = 120/506 (23%), Positives = 161/506 (31%), Gaps = 73/506 (14%)
Query: 811 PAPHTHPHPPWLPRTRSPSLWMGGHSYGLGHPALH-QNLPPGFPASVAGPVPSVFPLPQD 869
P P P PP LP +PS + QN A P P V Q
Sbjct: 638 PPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQ-SQS 696
Query: 870 APTQLVILPSEPTPHSAPHALADVMDQASLWPPMYGGRGPASHMQHP--GQLPVYSR--P 925
Q+++ P+ P P PP G A P LP +S P
Sbjct: 697 VKPQILVPPNGVVPPPPPPP-----------PPPTPGSAMAQLKPAPCAPSLPQFSAPPP 745
Query: 926 QLLRQQELYALQQQRAAQFQRKPEDQHLDLEEPAQE----KAPKSTHKPVA--LTPTAPG 979
L Q + Q P L + P + AP ST K VA +T AP
Sbjct: 746 PLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTST-KTVAPVVTQAAPP 804
Query: 980 APSPAAGPTK----LPPCCHPPDPKPPASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSA 1035
P+P P K P PP P P P P P P+ P + C P P S V S
Sbjct: 805 TPTPPVPPAKKQPAFPASYIPPSPPTP---PVPVPPPTLPKQQSFCAKPPPSPLSPVPSV 861
Query: 1036 EEKNGE--GQQSTADIITSEPDLP-PGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPG 1092
++ T + S+P P P + P + P V + P ++ +P
Sbjct: 862 VKQIASQFPPPPTPPAMESQPLKPVPANVAPQS------PPAVKAKPKWQPSSIPVPSPD 915
Query: 1093 AQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERGPQGKAADPSPLE 1152
P P + L PPP SP P A+P P + G GK +
Sbjct: 916 FPPPPPESSLVFPPPPPSPVPAPPP---------PPPPTASPTPDKSGSPGKKTSKTSSP 966
Query: 1153 GLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGEQGPSSGASSQVLEQRAGSPG- 1211
G ++ P T Q +S+ + E S S +GSP
Sbjct: 967 GGKK-----------PPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSK 1015
Query: 1212 -ALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDALVAATINL 1270
L P P + L L + G P + G D++V
Sbjct: 1016 ETLPPPAAPPKPGKLNLSGVNLPGVLQQ-------GCVSAKAPVLSGRGKDSVV----EF 1064
Query: 1271 GDLPSDSPPDPQPPAASGPPSTVPLP 1296
PSDS P PP P + +P
Sbjct: 1065 PSPPSDSDFPPPPPETELPLPPIEIP 1090
Score = 48.5 bits (114), Expect = 8e-05
Identities = 47/216 (21%), Positives = 75/216 (34%), Gaps = 13/216 (6%)
Query: 939 QRAAQFQRKPEDQHLDLEEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPD 998
+R Q + + + + P P + +P +TP PSP P PP PP
Sbjct: 582 KRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPP 641
Query: 999 PKPPASSPTPPPRPSAPCTLNVCPA-SSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLP 1057
P PP P P P SAP + P +R+++A + +G + + +
Sbjct: 642 PPPP---PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVK 698
Query: 1058 PGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLP---GEPPPCSPRSL 1114
P L P G+ P P T + +P P LP PPP +
Sbjct: 699 PQILVPPNGVVPPPPPP------PPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQV 752
Query: 1115 EEPGLLSGAREATQDLAATPYPTERGPQGKAADPSP 1150
+ ++ P P + P+ P+P
Sbjct: 753 QHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAP 788
Score = 40.8 bits (94), Expect = 0.018
Identities = 92/460 (20%), Positives = 132/460 (28%), Gaps = 62/460 (13%)
Query: 853 PASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADVMDQASLWPPMYGGRGPASH 912
P + + P P + P P P P P P P + A PM+ +
Sbjct: 618 PYTASQPSPPLPPPPPPPPP-----PPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITR 672
Query: 913 MQ----HPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLDLEEPAQEKAPKSTH 968
+Q H G L P +++ Q + Q P P P S
Sbjct: 673 LQNASQHSGALFKPPTPPVMQSQSV-------KPQILVPPNGVVPPPPPPPPPPTPGSAM 725
Query: 969 KPVALTPTAPGAPSPAAGPTKL------------PPCCHPPDPKPPASSPTPPPRPSAPC 1016
+ P AP P +A P L PP P P PP +P PP P P
Sbjct: 726 AQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPT---PPPPPPIPAPLPPQAPPKPL 782
Query: 1017 TLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVH 1076
P S+ V A T P +PP +P + PS
Sbjct: 783 VTIPAPTSTKTVAPVVTQAAPP------------TPTPPVPPAKKQPAFPASYIPPS--- 827
Query: 1077 SSNLEDPETMQTTAPGAQPEPTRTFLPGEPP-PCSPRSLEEPGLLSGAREATQDLAATPY 1135
P T P ++F PP P SP + S A
Sbjct: 828 ------PPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQ 881
Query: 1136 PTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGEQGPS 1195
P + P A P + + + P+ + P
Sbjct: 882 PLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP 941
Query: 1196 SGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPR 1255
++ ++GSPG + P ++ S + GA HP
Sbjct: 942 PPPTASPTPDKSGSPGKKTSKTSSPGGKKPP------PTPQRNSSIKSSSGA---EHPEP 992
Query: 1256 ALPGLDALVAATINLGDLPSDSPPDPQPPAASGPPSTVPL 1295
P +D+LV+ + S S PPAA P + L
Sbjct: 993 KRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNL 1032
Score = 34.3 bits (77), Expect = 1.7
Identities = 87/384 (22%), Positives = 125/384 (32%), Gaps = 42/384 (10%)
Query: 817 PHPPWLPRTRSPSLWMGGHSYGLGHPALHQNLPPGFPASVAGPVPSVFPLPQDAPTQLVI 876
P PP P S L + P + P P+S+ P P P P ++ LV
Sbjct: 870 PPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPES--SLVF 927
Query: 877 LPSEPTPHSAPHALADVMDQASLWPPMYGGRGP-ASHMQHPGQLPVYSRPQLLRQQELYA 935
P P+P AP AS P G G S PG PQ R + +
Sbjct: 928 PPPPPSPVPAPPPPPP--PTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQ--RNSSIKS 983
Query: 936 LQQQRAAQFQRKPEDQHLD-LEEPAQEKAPKSTHKPVALTPTAPGAPSPAAG--PTKLPP 992
+ +R D + PA+ +P P P PG + + P L
Sbjct: 984 SSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQ 1043
Query: 993 CCHPPD---------------PKPPASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEE 1037
C P PP+ S PPP P L + G+
Sbjct: 1044 GCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAV 1103
Query: 1038 KNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAP--GAQP 1095
N + QQ + + P PP RP L + + + TM T P P
Sbjct: 1104 VNPQPQQWSKMSVKKAP--PP--TRPKRNDSTRLT----QAEISEQPTMATVVPQVPTSP 1155
Query: 1096 EPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERGPQGKAADPSPLEGLQ 1155
+ + + PG + R+L+ + +++ A P T A P P E L
Sbjct: 1156 KSSLSVQPGFLADLN-RTLQRKSITRHGSLSSRMSRAEPTAT---MDDMALPPPPPELLS 1211
Query: 1156 ELQCAALLEAGGPEATGQAHSTQG 1179
+ Q A GG +G A +G
Sbjct: 1212 DQQKAGY---GGSHISGYATLRRG 1232
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 58.2 bits (139), Expect = 1e-07
Identities = 149/737 (20%), Positives = 235/737 (31%), Gaps = 90/737 (12%)
Query: 788 PPSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTRSPSLWMGGHSYGLGHPALHQN 847
P S+ P + P + + +PAP T P P+ +P+ PA
Sbjct: 224 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 283
Query: 848 LPPGFPASVAGPVPSVFPLP----QDAPTQ----LVILPSEPTPHSAPHALADVMDQASL 899
P + + P P P + APT P EPTP + + A
Sbjct: 284 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 343
Query: 900 WPPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKP-----EDQHLD 954
P P + P + P+ + ++ + ++P +
Sbjct: 344 TPKEPAPTAPKKPAPTTPKEPAPTTPK----EPAPTTTKEPSPTTPKEPAPTTTKSAPTT 399
Query: 955 LEEPA-----------QEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPA 1003
+EPA +E +P +T +P TP P +P P P PK PA
Sbjct: 400 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 459
Query: 1004 SSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRP 1063
+ T P P+ P P P + +A + +T + + P P
Sbjct: 460 PTTTKKPAPTTP--------KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 511
Query: 1064 MAGLGFSLPSDVHSSNLED--PETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLS 1121
L + P + + E+ P T + AP EP T P EP P +P+ EP +
Sbjct: 512 -EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT-TPKEPAPTTPK---EPAPTT 566
Query: 1122 GAREATQDLAATPYPTERGPQGKA-ADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGG 1180
A T T + P P+P +EL E A +T G
Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPAP----KELAPTTTKEPTSTTCDKPAPTTPKG 622
Query: 1181 AREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEG----EQPAPEEDELEEDELGQQS 1236
+E P A + + +P L++ ++PAP+ EL +
Sbjct: 623 TAPTTPKEPAPTTPKEPAPT---TPKGTAPTTLKEPAPTTPKKPAPK-------ELAPTT 672
Query: 1237 MEDSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAAS--GPPSTVP 1294
+ P + P P A T P+ + P+ PP S P+T
Sbjct: 673 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPT--TPKKPAPTTPETPPPTTSEVSTPTTTK 730
Query: 1295 LP---HSSGIHGIALLS-ELADLAIQRQRSERTVPEEEEDVLAFNLQHLATLATAWSLVE 1350
P H S LS E A++ E VP + A + T A +
Sbjct: 731 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP--AATKPEMTTTAKD----K 784
Query: 1351 AAGLDSSTAPAQPPTANPCSGPRLTPRMQILQRKDTWT------PKTKPVCPLKAAIDRL 1404
D T P A + T + + K T T T+ P K I L
Sbjct: 785 TTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFK--ITTL 842
Query: 1405 DTQEVGMRVRLAELQRRYKEKQRELARLQRKHDHERDESSRSPARRGPGRPRKRKHSSSL 1464
T + +V + E + + D + + +P + P + K+ S+
Sbjct: 843 KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK 902
Query: 1465 PAPRP------TGPLPR 1475
P P T P PR
Sbjct: 903 PKTMPRVRKPKTTPTPR 919
Score = 42.7 bits (99), Expect = 0.005
Identities = 44/182 (24%), Positives = 64/182 (35%), Gaps = 12/182 (6%)
Query: 956 EEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAP 1015
+EPA + T + PT P P+P + P PK PA + T P P+ P
Sbjct: 222 KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA------PTTPKEPAPTTTKEPAPTTP 275
Query: 1016 CTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDV 1075
P P + +SA E +T P P +
Sbjct: 276 KEPAPTTTKEPAP-TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 334
Query: 1076 HSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPY 1135
++ P T + AP A +P T P EP P +P+ EP + +E + P
Sbjct: 335 PTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPK---EPAPTT-TKEPSPTTPKEPA 389
Query: 1136 PT 1137
PT
Sbjct: 390 PT 391
Score = 39.3 bits (90), Expect = 0.051
Identities = 54/199 (27%), Positives = 73/199 (36%), Gaps = 26/199 (13%)
Query: 962 KAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPA--SSPTPPPRPSAPCTLN 1019
KA +T P TP P +P K P P +P P S+PT P P AP T
Sbjct: 200 KAETTTKGPALTTPKEPTPTTP-----KEPASTTPKEPTPTTIKSAPTTPKEP-APTTTK 253
Query: 1020 VCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSN 1079
P + P + +E + A T EP P + P + +
Sbjct: 254 SAPTTPKEPAP--TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP------TTPKEPAPTT 305
Query: 1080 LED--PETMQTTAPGAQPEPTRTFLPGEPPPC----SPRSLEEPGLLSGAREA--TQDLA 1131
+ P T + AP EPT T P EP P +P + +EP + + A T
Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPT-TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 364
Query: 1132 ATPYPTERGPQGKAADPSP 1150
A P E P +PSP
Sbjct: 365 APTTPKEPAPT-TTKEPSP 382
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 58.2 bits (139), Expect = 1e-07
Identities = 149/737 (20%), Positives = 235/737 (31%), Gaps = 90/737 (12%)
Query: 788 PPSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTRSPSLWMGGHSYGLGHPALHQN 847
P S+ P + P + + +PAP T P P+ +P+ PA
Sbjct: 265 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 324
Query: 848 LPPGFPASVAGPVPSVFPLP----QDAPTQ----LVILPSEPTPHSAPHALADVMDQASL 899
P + + P P P + APT P EPTP + + A
Sbjct: 325 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 384
Query: 900 WPPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKP-----EDQHLD 954
P P + P + P+ + ++ + ++P +
Sbjct: 385 TPKEPAPTAPKKPAPTTPKEPAPTTPK----EPAPTTTKEPSPTTPKEPAPTTTKSAPTT 440
Query: 955 LEEPA-----------QEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPA 1003
+EPA +E +P +T +P TP P +P P P PK PA
Sbjct: 441 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 500
Query: 1004 SSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRP 1063
+ T P P+ P P P + +A + +T + + P P
Sbjct: 501 PTTTKKPAPTTP--------KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 552
Query: 1064 MAGLGFSLPSDVHSSNLED--PETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLS 1121
L + P + + E+ P T + AP EP T P EP P +P+ EP +
Sbjct: 553 -EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT-TPKEPAPTTPK---EPAPTT 607
Query: 1122 GAREATQDLAATPYPTERGPQGKA-ADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGG 1180
A T T + P P+P +EL E A +T G
Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAP----KELAPTTTKEPTSTTCDKPAPTTPKG 663
Query: 1181 AREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEG----EQPAPEEDELEEDELGQQS 1236
+E P A + + +P L++ ++PAP+ EL +
Sbjct: 664 TAPTTPKEPAPTTPKEPAPT---TPKGTAPTTLKEPAPTTPKKPAPK-------ELAPTT 713
Query: 1237 MEDSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAAS--GPPSTVP 1294
+ P + P P A T P+ + P+ PP S P+T
Sbjct: 714 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPT--TPKKPAPTTPETPPPTTSEVSTPTTTK 771
Query: 1295 LP---HSSGIHGIALLS-ELADLAIQRQRSERTVPEEEEDVLAFNLQHLATLATAWSLVE 1350
P H S LS E A++ E VP + A + T A +
Sbjct: 772 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP--AATKPEMTTTAKD----K 825
Query: 1351 AAGLDSSTAPAQPPTANPCSGPRLTPRMQILQRKDTWT------PKTKPVCPLKAAIDRL 1404
D T P A + T + + K T T T+ P K I L
Sbjct: 826 TTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFK--ITTL 883
Query: 1405 DTQEVGMRVRLAELQRRYKEKQRELARLQRKHDHERDESSRSPARRGPGRPRKRKHSSSL 1464
T + +V + E + + D + + +P + P + K+ S+
Sbjct: 884 KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK 943
Query: 1465 PAPRP------TGPLPR 1475
P P T P PR
Sbjct: 944 PKTMPRVRKPKTTPTPR 960
Score = 42.7 bits (99), Expect = 0.005
Identities = 44/182 (24%), Positives = 64/182 (35%), Gaps = 12/182 (6%)
Query: 956 EEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAP 1015
+EPA + T + PT P P+P + P PK PA + T P P+ P
Sbjct: 263 KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA------PTTPKEPAPTTTKEPAPTTP 316
Query: 1016 CTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDV 1075
P P + +SA E +T P P +
Sbjct: 317 KEPAPTTTKEPAP-TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 375
Query: 1076 HSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPY 1135
++ P T + AP A +P T P EP P +P+ EP + +E + P
Sbjct: 376 PTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPK---EPAPTT-TKEPSPTTPKEPA 430
Query: 1136 PT 1137
PT
Sbjct: 431 PT 432
Score = 39.3 bits (90), Expect = 0.051
Identities = 54/199 (27%), Positives = 73/199 (36%), Gaps = 26/199 (13%)
Query: 962 KAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPA--SSPTPPPRPSAPCTLN 1019
KA +T P TP P +P K P P +P P S+PT P P AP T
Sbjct: 241 KAETTTKGPALTTPKEPTPTTP-----KEPASTTPKEPTPTTIKSAPTTPKEP-APTTTK 294
Query: 1020 VCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSN 1079
P + P + +E + A T EP P + P + +
Sbjct: 295 SAPTTPKEPAP--TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP------TTPKEPAPTT 346
Query: 1080 LED--PETMQTTAPGAQPEPTRTFLPGEPPPC----SPRSLEEPGLLSGAREA--TQDLA 1131
+ P T + AP EPT T P EP P +P + +EP + + A T
Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPT-TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 405
Query: 1132 ATPYPTERGPQGKAADPSP 1150
A P E P +PSP
Sbjct: 406 APTTPKEPAPT-TTKEPSP 423
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 58.2 bits (139), Expect = 1e-07
Identities = 149/737 (20%), Positives = 235/737 (31%), Gaps = 90/737 (12%)
Query: 788 PPSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTRSPSLWMGGHSYGLGHPALHQN 847
P S+ P + P + + +PAP T P P+ +P+ PA
Sbjct: 317 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 376
Query: 848 LPPGFPASVAGPVPSVFPLP----QDAPTQ----LVILPSEPTPHSAPHALADVMDQASL 899
P + + P P P + APT P EPTP + + A
Sbjct: 377 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 436
Query: 900 WPPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKP-----EDQHLD 954
P P + P + P+ + ++ + ++P +
Sbjct: 437 TPKEPAPTAPKKPAPTTPKEPAPTTPK----EPAPTTTKEPSPTTPKEPAPTTTKSAPTT 492
Query: 955 LEEPA-----------QEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPA 1003
+EPA +E +P +T +P TP P +P P P PK PA
Sbjct: 493 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 552
Query: 1004 SSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRP 1063
+ T P P+ P P P + +A + +T + + P P
Sbjct: 553 PTTTKKPAPTTP--------KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 604
Query: 1064 MAGLGFSLPSDVHSSNLED--PETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLS 1121
L + P + + E+ P T + AP EP T P EP P +P+ EP +
Sbjct: 605 -EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT-TPKEPAPTTPK---EPAPTT 659
Query: 1122 GAREATQDLAATPYPTERGPQGKA-ADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGG 1180
A T T + P P+P +EL E A +T G
Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPTTPKKPAP----KELAPTTTKEPTSTTCDKPAPTTPKG 715
Query: 1181 AREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEG----EQPAPEEDELEEDELGQQS 1236
+E P A + + +P L++ ++PAP+ EL +
Sbjct: 716 TAPTTPKEPAPTTPKEPAPT---TPKGTAPTTLKEPAPTTPKKPAPK-------ELAPTT 765
Query: 1237 MEDSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAAS--GPPSTVP 1294
+ P + P P A T P+ + P+ PP S P+T
Sbjct: 766 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPT--TPKKPAPTTPETPPPTTSEVSTPTTTK 823
Query: 1295 LP---HSSGIHGIALLS-ELADLAIQRQRSERTVPEEEEDVLAFNLQHLATLATAWSLVE 1350
P H S LS E A++ E VP + A + T A +
Sbjct: 824 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP--AATKPEMTTTAKD----K 877
Query: 1351 AAGLDSSTAPAQPPTANPCSGPRLTPRMQILQRKDTWT------PKTKPVCPLKAAIDRL 1404
D T P A + T + + K T T T+ P K I L
Sbjct: 878 TTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFK--ITTL 935
Query: 1405 DTQEVGMRVRLAELQRRYKEKQRELARLQRKHDHERDESSRSPARRGPGRPRKRKHSSSL 1464
T + +V + E + + D + + +P + P + K+ S+
Sbjct: 936 KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK 995
Query: 1465 PAPRP------TGPLPR 1475
P P T P PR
Sbjct: 996 PKTMPRVRKPKTTPTPR 1012
Score = 42.7 bits (99), Expect = 0.005
Identities = 44/182 (24%), Positives = 64/182 (35%), Gaps = 12/182 (6%)
Query: 956 EEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAP 1015
+EPA + T + PT P P+P + P PK PA + T P P+ P
Sbjct: 315 KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA------PTTPKEPAPTTTKEPAPTTP 368
Query: 1016 CTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDV 1075
P P + +SA E +T P P +
Sbjct: 369 KEPAPTTTKEPAP-TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 427
Query: 1076 HSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPY 1135
++ P T + AP A +P T P EP P +P+ EP + +E + P
Sbjct: 428 PTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPK---EPAPTT-TKEPSPTTPKEPA 482
Query: 1136 PT 1137
PT
Sbjct: 483 PT 484
Score = 39.3 bits (90), Expect = 0.051
Identities = 54/199 (27%), Positives = 73/199 (36%), Gaps = 26/199 (13%)
Query: 962 KAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPA--SSPTPPPRPSAPCTLN 1019
KA +T P TP P +P K P P +P P S+PT P P AP T
Sbjct: 293 KAETTTKGPALTTPKEPTPTTP-----KEPASTTPKEPTPTTIKSAPTTPKEP-APTTTK 346
Query: 1020 VCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSN 1079
P + P + +E + A T EP P + P + +
Sbjct: 347 SAPTTPKEPAP--TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP------TTPKEPAPTT 398
Query: 1080 LED--PETMQTTAPGAQPEPTRTFLPGEPPPC----SPRSLEEPGLLSGAREA--TQDLA 1131
+ P T + AP EPT T P EP P +P + +EP + + A T
Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPT-TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 457
Query: 1132 ATPYPTERGPQGKAADPSP 1150
A P E P +PSP
Sbjct: 458 APTTPKEPAPT-TTKEPSP 475
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 58.2 bits (139), Expect = 1e-07
Identities = 149/737 (20%), Positives = 235/737 (31%), Gaps = 90/737 (12%)
Query: 788 PPSSCPGDLAPHLMMQSGQLGGDPAPHTHPHPPWLPRTRSPSLWMGGHSYGLGHPALHQN 847
P S+ P + P + + +PAP T P P+ +P+ PA
Sbjct: 358 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 417
Query: 848 LPPGFPASVAGPVPSVFPLP----QDAPTQ----LVILPSEPTPHSAPHALADVMDQASL 899
P + + P P P + APT P EPTP + + A
Sbjct: 418 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 477
Query: 900 WPPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKP-----EDQHLD 954
P P + P + P+ + ++ + ++P +
Sbjct: 478 TPKEPAPTAPKKPAPTTPKEPAPTTPK----EPAPTTTKEPSPTTPKEPAPTTTKSAPTT 533
Query: 955 LEEPA-----------QEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPA 1003
+EPA +E +P +T +P TP P +P P P PK PA
Sbjct: 534 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 593
Query: 1004 SSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRP 1063
+ T P P+ P P P + +A + +T + + P P
Sbjct: 594 PTTTKKPAPTTP--------KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 645
Query: 1064 MAGLGFSLPSDVHSSNLED--PETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLS 1121
L + P + + E+ P T + AP EP T P EP P +P+ EP +
Sbjct: 646 -EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT-TPKEPAPTTPK---EPAPTT 700
Query: 1122 GAREATQDLAATPYPTERGPQGKA-ADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGG 1180
A T T + P P+P +EL E A +T G
Sbjct: 701 PKETAPTTPKGTAPTTLKEPAPTTPKKPAP----KELAPTTTKEPTSTTCDKPAPTTPKG 756
Query: 1181 AREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEG----EQPAPEEDELEEDELGQQS 1236
+E P A + + +P L++ ++PAP+ EL +
Sbjct: 757 TAPTTPKEPAPTTPKEPAPT---TPKGTAPTTLKEPAPTTPKKPAPK-------ELAPTT 806
Query: 1237 MEDSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAAS--GPPSTVP 1294
+ P + P P A T P+ + P+ PP S P+T
Sbjct: 807 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPT--TPKKPAPTTPETPPPTTSEVSTPTTTK 864
Query: 1295 LP---HSSGIHGIALLS-ELADLAIQRQRSERTVPEEEEDVLAFNLQHLATLATAWSLVE 1350
P H S LS E A++ E VP + A + T A +
Sbjct: 865 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP--AATKPEMTTTAKD----K 918
Query: 1351 AAGLDSSTAPAQPPTANPCSGPRLTPRMQILQRKDTWT------PKTKPVCPLKAAIDRL 1404
D T P A + T + + K T T T+ P K I L
Sbjct: 919 TTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFK--ITTL 976
Query: 1405 DTQEVGMRVRLAELQRRYKEKQRELARLQRKHDHERDESSRSPARRGPGRPRKRKHSSSL 1464
T + +V + E + + D + + +P + P + K+ S+
Sbjct: 977 KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK 1036
Query: 1465 PAPRP------TGPLPR 1475
P P T P PR
Sbjct: 1037 PKTMPRVRKPKTTPTPR 1053
Score = 42.7 bits (99), Expect = 0.005
Identities = 44/182 (24%), Positives = 64/182 (35%), Gaps = 12/182 (6%)
Query: 956 EEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAP 1015
+EPA + T + PT P P+P + P PK PA + T P P+ P
Sbjct: 356 KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA------PTTPKEPAPTTTKEPAPTTP 409
Query: 1016 CTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDV 1075
P P + +SA E +T P P +
Sbjct: 410 KEPAPTTTKEPAP-TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 468
Query: 1076 HSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPY 1135
++ P T + AP A +P T P EP P +P+ EP + +E + P
Sbjct: 469 PTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPK---EPAPTT-TKEPSPTTPKEPA 523
Query: 1136 PT 1137
PT
Sbjct: 524 PT 525
Score = 39.3 bits (90), Expect = 0.051
Identities = 54/199 (27%), Positives = 73/199 (36%), Gaps = 26/199 (13%)
Query: 962 KAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPA--SSPTPPPRPSAPCTLN 1019
KA +T P TP P +P K P P +P P S+PT P P AP T
Sbjct: 334 KAETTTKGPALTTPKEPTPTTP-----KEPASTTPKEPTPTTIKSAPTTPKEP-APTTTK 387
Query: 1020 VCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSN 1079
P + P + +E + A T EP P + P + +
Sbjct: 388 SAPTTPKEPAP--TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP------TTPKEPAPTT 439
Query: 1080 LED--PETMQTTAPGAQPEPTRTFLPGEPPPC----SPRSLEEPGLLSGAREA--TQDLA 1131
+ P T + AP EPT T P EP P +P + +EP + + A T
Sbjct: 440 PKKPAPTTPKEPAPTTPKEPTPT-TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 498
Query: 1132 ATPYPTERGPQGKAADPSP 1150
A P E P +PSP
Sbjct: 499 APTTPKEPAPT-TTKEPSP 516
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 57.8 bits (138), Expect = 1e-07
Identities = 138/572 (24%), Positives = 186/572 (32%), Gaps = 96/572 (16%)
Query: 787 HPPSSCPGDLAPHLMMQSGQLGGDPA-PHTHPHPPWLPRTRSPSLWMGGHSYGLGHPALH 845
H P + P SG PA P + P PP+L R+ P + P L
Sbjct: 541 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV 600
Query: 846 Q---NLPPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPT--PHSAPHALADVMDQASLW 900
LPP P+S F P+ +P V P P P P L+
Sbjct: 601 PLTLALPPAPPSSCHQNTSGSFRRPE-SPRPRVSFPKTPEVGPGPPPGPLSKAPQPV--- 656
Query: 901 PPMYG---GRGPA----------SHMQHPGQLPVYSR---------PQLLRQQELYALQQ 938
PP G RGP + P + + + +R++E QQ
Sbjct: 657 PPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEE---QQ 713
Query: 939 QRAAQFQRKP--EDQHLDLEEP-AQEKAPKSTHKPVALTPTAPGA------------PSP 983
Q A +P ++ L+ P + AP +T VA+T T P P
Sbjct: 714 QHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPP 773
Query: 984 AAGPTKLPPCCHPPDPKPPASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQ 1043
A P PP P P P P PPP P++ R A G
Sbjct: 774 ALPPP--PPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGP 831
Query: 1044 QSTADIITSEPD----LPPGYLRPMAGLGFSLPSDVHSSNLE---DPETMQTTAPGAQPE 1096
T P LPP P A G PS SS P + A G +P
Sbjct: 832 LPTTQYSPGPPSGATALPPTSAAPSA-QGSPQPSASSSSQFSTSGGPWARERRA-GEEPV 889
Query: 1097 PTRTFLPGEPPPCS-PRSLEEPGLLSGAREATQDLAATPYPTERGPQGKAADPSPLE-GL 1154
P PPP S P + E +L A + L + P P + G
Sbjct: 890 PGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGT 949
Query: 1155 QEL--QCAALLEAGGPEA-TGQAHSTQGGAREERSREEGEQGPSSGASSQVLEQRAGSPG 1211
+ L A EAGG A +G Q ++E R S G + E RA +
Sbjct: 950 ERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPR--EGRAKAKA 1007
Query: 1212 ALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDALVAATINLG 1271
+ E + +L+ +E+ Q E S D GGA + PP A
Sbjct: 1008 KVPKEKSRRVLGNLDLQSEEI--QGREKSRPDLGGA-SKAKPPTA--------------- 1049
Query: 1272 DLPSDSPPDPQPPAASGPPSTVPLPHSSGIHG 1303
P PP+A PS P P S+ + G
Sbjct: 1050 ---------PAPPSAPA-PSAQPTPPSASVPG 1071
Score = 48.9 bits (115), Expect = 6e-05
Identities = 130/561 (23%), Positives = 181/561 (32%), Gaps = 119/561 (21%)
Query: 813 PHTHPHPPWLPRTRSPSLWMGGHSYGLGHPALHQNLPPGFPASVAGPVPSVFPLPQDAPT 872
PH P WLP R S +G P L LPP +S P + APT
Sbjct: 33 PHPPPRSAWLPGGRC--------SASIGQPPLPAPLPPSHGSSSGHPSKPYYA--PGAPT 82
Query: 873 QLVILPSEPTPHSAPHALADVMDQASLWPPMYGGRGPASHMQHPGQLPVYSRPQLLRQQE 932
+ + H AL Q LW + G +H + LR
Sbjct: 83 PRPLHGKLESLHGCVQALLREPAQPGLWEQL----GQLYESEHDSEEATRCYHSALRYGG 138
Query: 933 LYA--------LQQQRAAQFQR----------KPEDQ-----HLDLEEP--AQEKAP--K 965
+A LQQ + F P +Q HL+ + A+ P K
Sbjct: 139 SFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRNYGAKRGGPPVK 198
Query: 966 STHKPVALTPTAPGAPSPAAGP-----------------TKLPPCCH-PPDPKPPASSPT 1007
+P + P P A S +G T LPP PP P PP P
Sbjct: 199 RAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPP 258
Query: 1008 PPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEP--DLPPGYLRPMA 1065
PPP P P P PG + G ++ +A E LP Y
Sbjct: 259 PPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPY----- 313
Query: 1066 GLGFSLPSDVHSSNLEDPETMQTTAPGAQPEP----TRTFLPGEPPPCSPRSLEEPGLLS 1121
P+ ++++ + PG P P + LP PP S L E +
Sbjct: 314 ----PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGS--DLRESRVQR 367
Query: 1122 GAREATQDLAAT----PYPTERGP-----------------QGKAADPSP-LEGLQELQC 1159
+++ AAT PY R P + +P+P + G Q
Sbjct: 368 SRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQT 427
Query: 1160 AALLEAGGPEATGQAHSTQG---GAREERSREEGEQGPSSGASSQV--LEQRAGSPGALE 1214
AL + AHS++ GA GPSS L + P L+
Sbjct: 428 PALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLK 487
Query: 1215 DEGEQPAPEEDE-LEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDALV---AATINL 1270
+ A E+ E LEE G + G P + PP LP + + A+ ++
Sbjct: 488 GPACRAAREDGEILEELFFGTE----------GPPRPAPPP--LPHREGFLGPPASRFSV 535
Query: 1271 GDLPSDSPPDPQPPAASGPPS 1291
G S +PP P P S S
Sbjct: 536 GTQDSHTPPTPPTPTTSSSNS 556
Score = 40.0 bits (92), Expect = 0.030
Identities = 74/327 (22%), Positives = 106/327 (32%), Gaps = 53/327 (16%)
Query: 981 PSPAAGPTKLPPCCHPPDPKPPASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNG 1040
P PA T PP PP P PP S C P S SRV+ + +
Sbjct: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
Query: 1041 EGQQSTADIITSEPDLPPGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRT 1100
+T + P PPG LP SS+ + T G +P P
Sbjct: 374 VSPAATTACVPYAPSRPPG-----------LPGTTTSSS--SSSSSNTGLRGVEPNPG-- 418
Query: 1101 FLPGEPPPCSPRSLE-------EPGLLSGAREATQDLAATPYPTERGPQGKAADPSPLEG 1153
+PG +P +LE P S + AATP+ + P G ++ P P
Sbjct: 419 -IPGADHYQTP-ALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSL--PPGPSSPPPP--- 471
Query: 1154 LQELQCAALLEAGGPEATGQAHSTQGGAREERSREE---GEQGPSSGASSQVLEQRA--G 1208
C LL P A + + + + EE G +GP A + + G
Sbjct: 472 ----PCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLG 527
Query: 1209 SPGALEDEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDALVAATI 1268
P + G Q + + A S PP +A +I
Sbjct: 528 PPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPP------PPYLARSI 581
Query: 1269 NLGDLPSDSPPDPQPPAASGPPSTVPL 1295
+ P P+PP+ + P PL
Sbjct: 582 D---------PLPRPPSPAQNPQDPPL 599
Score = 38.5 bits (88), Expect = 0.088
Identities = 62/235 (26%), Positives = 84/235 (35%), Gaps = 51/235 (21%)
Query: 1447 PARRGPGRPRKRKHSSSLPAP--------------------RPTGPLPRSDGKKVKAVRT 1486
P R+G P +++ SLP P P GP PR G +
Sbjct: 292 PERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAE------ 345
Query: 1487 SLGLLCAELRGGSG-GEPAKKRSKLERSVYAGLQTASVEKAQCKKSSCQGGLAPSVAHRV 1545
S G L A GS E +RS+++ SV TA V A + G S +
Sbjct: 346 SHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSS 405
Query: 1546 AQ--LKPKVKSKGLPTGLSSFQQK--EATPGGRIREKL--SRAKSAKVSGATRH-PQPKG 1598
+ L+ + G+P G +Q E + GR+ SR AT H P G
Sbjct: 406 SNTGLRGVEPNPGIP-GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPG 464
Query: 1599 HGSRETPRCP------------AQPSVAASQEAGNGYDSEDCEGLLGTEAPPREA 1641
S P CP P+ A++E G + E GTE PPR A
Sbjct: 465 PSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILE----ELFFGTEGPPRPA 515
Score = 37.7 bits (86), Expect = 0.15
Identities = 90/400 (22%), Positives = 117/400 (29%), Gaps = 92/400 (23%)
Query: 956 EEPAQEKAPKSTHKPVALTPTAPGAPSPAAGP-TKLP--PCCHPPDPKPPASSPTPPPRP 1012
+ PA E + P A + P +PAA P LP P PP P P P PP
Sbjct: 426 QTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPP--- 482
Query: 1013 SAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGFSLP 1072
PA GP R A ++GE + P P L G P
Sbjct: 483 ---------PAWLKGPACR---AAREDGEILEELFFGTEGPPRPAPPPLPHREGF-LGPP 529
Query: 1073 SDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAA 1132
+ S +D T P P P + S G S +
Sbjct: 530 ASRFSVGTQDSHTP----------------PTPPTPTTSSSNSNSGSHSSSPAGPVSFPP 573
Query: 1133 TPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGA--REERSR--- 1187
PY R PSP + Q+ L A P H G+ R E R
Sbjct: 574 PPY-LARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRV 632
Query: 1188 -----EEGEQGPSSGASSQVLEQRAGSPGALEDEGEQ-----PAPEEDELEE-------- 1229
E GP G S+ + G L G + P P ED+ EE
Sbjct: 633 SFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILP 692
Query: 1230 ----------DELGQQSMEDSEEDCGGAPD----------------NSHPPRALPGLDAL 1263
DE ++ E + + G AP ++ P P +
Sbjct: 693 DGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVT 752
Query: 1264 VAATINLGDLPSD----SPP---DPQPPAASGPPSTVPLP 1296
T + PP P PP A PP + P P
Sbjct: 753 TTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQP 792
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 57.0 bits (136), Expect = 2e-07
Identities = 74/270 (27%), Positives = 92/270 (34%), Gaps = 59/270 (21%)
Query: 788 PP--SSCPGDLAPHLMMQSGQLGGDPA-PHTHPHPPWLPRTRSPSLWMGGHSYGLGHPAL 844
PP +S P + P+ M G GG PH+ PHP PSL GGH GHP
Sbjct: 366 PPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHP-------LPSL-TGGHG---GHPMQ 414
Query: 845 HQNLPPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADVMDQASLWPP-- 902
H P P P + P P P PH H MDQ P
Sbjct: 415 HNPNGP--------PPPWMQPPPP---------PMNQGPHPPGHHGPPPMDQYLGSTPVG 457
Query: 903 -----MYGGRG----PASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHL 953
++ G+G P M P P +P L QQQ+ P +
Sbjct: 458 SGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSM 517
Query: 954 DLEEPA--QEKAPKST-----------HKPVALTPTAPGAPSPAAGPTK--LPPCCHPPD 998
P Q+ +T + A +PGAP PT LPP PP
Sbjct: 518 ASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPP- 576
Query: 999 PKPPASSPTPPPRPSAPCTLNVCPASSPGP 1028
PP + P PPP P + + P GP
Sbjct: 577 -LPPGAPPPPPPPPPGSAGMMIPPRGGDGP 605
Score = 47.8 bits (112), Expect = 1e-04
Identities = 63/291 (21%), Positives = 85/291 (29%), Gaps = 63/291 (21%)
Query: 853 PASVAG--PVPSVFPLPQDAPTQLVILPSEPTP----------------HSAPHALADVM 894
PA+ A P PS+ Q P + PSE P HS PH L +
Sbjct: 346 PAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLT 405
Query: 895 DQASLWPPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQRKPEDQHLD 954
P + GP P P+ P
Sbjct: 406 GGHGGHPMQHNPNGPPPPWMQPPPPPMNQGP----------------------------- 436
Query: 955 LEEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPP---CCHPPDPKPPASSPTPPPR 1011
P P + + TP G G +PP PP P PP+ P PPP
Sbjct: 437 --HPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPS 494
Query: 1012 PSAP--CTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAGLGF 1069
P P P P S + S+ + +T +PP + A
Sbjct: 495 GPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAA--- 551
Query: 1070 SLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLL 1120
+ + ++ TM PG QP PG PPP P G++
Sbjct: 552 --AASPGAPQMQGNPTMVPLPPGVQP----PLPPGAPPPPPPPPPGSAGMM 596
Score = 35.0 bits (79), Expect = 0.97
Identities = 90/372 (24%), Positives = 121/372 (32%), Gaps = 82/372 (22%)
Query: 943 QFQRKPEDQHLDLEEPAQEKAPKSTHKPVALTPTAPGAPSPAA-GPTKLP---PCCHPPD 998
+FQR + Q AQ+KA + + ++L AP PA+ G T P P P
Sbjct: 293 KFQRPGDPQS------AQDKA-RMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPR 345
Query: 999 PKPPASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPP 1058
P PA++P PP S T + P + GP S R +G G P P
Sbjct: 346 PAAPANNPPPPSLMST--TQSRPPWMNSGP-SESRPYHGMHGGGPGGPG----GGPHSFP 398
Query: 1059 GYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPG 1118
L + G P H+ N P MQ P P G PP
Sbjct: 399 HPLPSLTGGHGGHPMQ-HNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPP----------- 446
Query: 1119 LLSGAREATQDLAATPYPTE--RGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHS 1176
Q L +TP + R QGK P P G+ + P +GQ
Sbjct: 447 -------MDQYLGSTPVGSGVYRLHQGKGMMPPPPMGM--------MPPPPPPPSGQPPP 491
Query: 1177 TQGGAREERSREEGEQGP-----SSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDE 1231
G +++ + P SS ASS L + + G P
Sbjct: 492 PPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPP-------- 543
Query: 1232 LGQQSMEDSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAASG--P 1289
Q + + GAP P +P PP QPP G P
Sbjct: 544 --WQQQQAAAAASPGAPQMQGNPTMVP------------------LPPGVQPPLPPGAPP 583
Query: 1290 PSTVPLPHSSGI 1301
P P P S+G+
Sbjct: 584 PPPPPPPGSAGM 595
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 131,460,319
Number of Sequences: 37866
Number of extensions: 8207596
Number of successful extensions: 74059
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 358
Number of HSP's successfully gapped in prelim test: 1674
Number of HSP's that attempted gapping in prelim test: 41227
Number of HSP's gapped (non-prelim): 23572
length of query: 2608
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2489
effective length of database: 13,741,464
effective search space: 34202503896
effective search space used: 34202503896
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.