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Search of human proteins with 112420992
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|112420992 crumbs homolog 2 [Homo sapiens]
(1285 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|112420992 crumbs homolog 2 [Homo sapiens] 2779 0.0
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 699 0.0
gi|148833508 notch1 preproprotein [Homo sapiens] 359 8e-99
gi|24041035 notch 2 preproprotein [Homo sapiens] 343 5e-94
gi|134244285 Notch homolog 3 [Homo sapiens] 336 7e-92
gi|55770876 notch4 preproprotein [Homo sapiens] 325 2e-88
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 308 2e-83
gi|4557679 jagged 1 precursor [Homo sapiens] 297 4e-80
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 289 1e-77
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 274 5e-73
gi|122937283 6720455I24Rik homolog [Homo sapiens] 256 7e-68
gi|116235485 delta-notch-like EGF repeat-containing transmembran... 250 5e-66
gi|110735443 delta-like 1 [Homo sapiens] 243 7e-64
gi|148886654 polydom [Homo sapiens] 231 3e-60
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 220 6e-57
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 214 3e-55
gi|4759146 slit homolog 2 [Homo sapiens] 200 8e-51
gi|11321571 slit homolog 3 [Homo sapiens] 198 2e-50
gi|126091152 cubilin [Homo sapiens] 181 5e-45
gi|110347437 latent transforming growth factor beta binding prot... 175 3e-43
gi|110347412 latent transforming growth factor beta binding prot... 175 3e-43
gi|110347431 latent transforming growth factor beta binding prot... 175 3e-43
gi|188528675 slit homolog 1 [Homo sapiens] 172 2e-42
gi|8393264 delta-like 3 protein isoform 1 precursor [Homo sapiens] 170 9e-42
gi|45243561 delta-like 3 protein isoform 2 precursor [Homo sapiens] 170 9e-42
gi|45593147 EGF-like-domain, multiple 9 [Homo sapiens] 169 2e-41
gi|45545431 EGF-like-domain, multiple 9 [Homo sapiens] 169 2e-41
gi|74136023 delta-like 1 homolog [Homo sapiens] 157 8e-38
gi|194328809 latent transforming growth factor beta binding prot... 153 9e-37
gi|18497288 latent transforming growth factor beta binding prote... 153 9e-37
>gi|112420992 crumbs homolog 2 [Homo sapiens]
Length = 1285
Score = 2779 bits (7203), Expect = 0.0
Identities = 1285/1285 (100%), Positives = 1285/1285 (100%)
Query: 1 MALARPGTPDPQALASVLLLLLWAPALSLLAGTVPSEPPSACASDPCAPGTECQATESGG 60
MALARPGTPDPQALASVLLLLLWAPALSLLAGTVPSEPPSACASDPCAPGTECQATESGG
Sbjct: 1 MALARPGTPDPQALASVLLLLLWAPALSLLAGTVPSEPPSACASDPCAPGTECQATESGG 60
Query: 61 YTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHG 120
YTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHG
Sbjct: 61 YTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHG 120
Query: 121 ATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTR 180
ATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTR
Sbjct: 121 ATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTR 180
Query: 181 CQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLE 240
CQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLE
Sbjct: 181 CQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLE 240
Query: 241 GLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRH 300
GLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRH
Sbjct: 241 GLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRH 300
Query: 301 AAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVD 360
AAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVD
Sbjct: 301 AAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVD 360
Query: 361 ECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVH 420
ECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVH
Sbjct: 361 ECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVH 420
Query: 421 SYVCHCPPGTHGPFCGQNTTFSVMAGSPIQASVPAGGPLGLALRFRTTLPAGTLATRNDT 480
SYVCHCPPGTHGPFCGQNTTFSVMAGSPIQASVPAGGPLGLALRFRTTLPAGTLATRNDT
Sbjct: 421 SYVCHCPPGTHGPFCGQNTTFSVMAGSPIQASVPAGGPLGLALRFRTTLPAGTLATRNDT 480
Query: 481 KESLELALVAATLQATLWSYSTTVLVLRLPDLALNDGHWHQVEVVLHLATLELRLWHEGC 540
KESLELALVAATLQATLWSYSTTVLVLRLPDLALNDGHWHQVEVVLHLATLELRLWHEGC
Sbjct: 481 KESLELALVAATLQATLWSYSTTVLVLRLPDLALNDGHWHQVEVVLHLATLELRLWHEGC 540
Query: 541 PARLCVASGPVALASTASATPLPAGISSAQLGDATFAGCLQDVRVDGHLLLPEDLGENVL 600
PARLCVASGPVALASTASATPLPAGISSAQLGDATFAGCLQDVRVDGHLLLPEDLGENVL
Sbjct: 541 PARLCVASGPVALASTASATPLPAGISSAQLGDATFAGCLQDVRVDGHLLLPEDLGENVL 600
Query: 601 LGCERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIPAATFGLGGAPSSASF 660
LGCERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIPAATFGLGGAPSSASF
Sbjct: 601 LGCERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIPAATFGLGGAPSSASF 660
Query: 661 LLQELPGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPGR 720
LLQELPGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPGR
Sbjct: 661 LLQELPGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPGR 720
Query: 721 WDDGLRHLVMLSFGPDQLQDLGQHVHVGGRLLAADSQPWGGPFRGCLQDLRLDGCHLPFF 780
WDDGLRHLVMLSFGPDQLQDLGQHVHVGGRLLAADSQPWGGPFRGCLQDLRLDGCHLPFF
Sbjct: 721 WDDGLRHLVMLSFGPDQLQDLGQHVHVGGRLLAADSQPWGGPFRGCLQDLRLDGCHLPFF 780
Query: 781 PLPLDNSSQPSELGGRQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGP 840
PLPLDNSSQPSELGGRQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGP
Sbjct: 781 PLPLDNSSQPSELGGRQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGP 840
Query: 841 TCAQQLWCPGQPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGHNASSGRLLGGLSLAF 900
TCAQQLWCPGQPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGHNASSGRLLGGLSLAF
Sbjct: 841 TCAQQLWCPGQPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGHNASSGRLLGGLSLAF 900
Query: 901 RTRDSEAWLLRAAAGALEGVWLAVRNGSLAGGVRGGHGLPGAVLPIPGPRVADGAWHRVR 960
RTRDSEAWLLRAAAGALEGVWLAVRNGSLAGGVRGGHGLPGAVLPIPGPRVADGAWHRVR
Sbjct: 901 RTRDSEAWLLRAAAGALEGVWLAVRNGSLAGGVRGGHGLPGAVLPIPGPRVADGAWHRVR 960
Query: 961 LAMERPAATTSRWLLWLDGAATPVALRGLASDLGFLQGPGAVRILLAENFTGCLGRVALG 1020
LAMERPAATTSRWLLWLDGAATPVALRGLASDLGFLQGPGAVRILLAENFTGCLGRVALG
Sbjct: 961 LAMERPAATTSRWLLWLDGAATPVALRGLASDLGFLQGPGAVRILLAENFTGCLGRVALG 1020
Query: 1021 GLPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFAC 1080
GLPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFAC
Sbjct: 1021 GLPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFAC 1080
Query: 1081 ACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSL 1140
ACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSL
Sbjct: 1081 ACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSL 1140
Query: 1141 NVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICN 1200
NVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICN
Sbjct: 1141 NVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICN 1200
Query: 1201 ARFSGQFCEVAKGLPLPLPFPLLEVAVPAACACLLLLLLGLLSGILAARKRRQSEGTYSP 1260
ARFSGQFCEVAKGLPLPLPFPLLEVAVPAACACLLLLLLGLLSGILAARKRRQSEGTYSP
Sbjct: 1201 ARFSGQFCEVAKGLPLPLPFPLLEVAVPAACACLLLLLLGLLSGILAARKRRQSEGTYSP 1260
Query: 1261 SQQEVAGARLEMDSVLKVPPEERLI 1285
SQQEVAGARLEMDSVLKVPPEERLI
Sbjct: 1261 SQQEVAGARLEMDSVLKVPPEERLI 1285
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 699 bits (1804), Expect = 0.0
Identities = 435/1460 (29%), Positives = 649/1460 (44%), Gaps = 242/1460 (16%)
Query: 13 ALASVLLLLLWAPALSLLA---GTVPSEPPSACASDPCAPGTECQA-TESGGYTCGPMEP 68
AL ++ LL++ + SLL + ++ + C S+ C + C+ ++ +C
Sbjct: 2 ALKNINYLLIFYLSFSLLIYIKNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTAN 61
Query: 69 R----------GCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCH 118
C + PC A CV P F C C PG+ G CE I C C
Sbjct: 62 NLDKDCDNMKDPCFSNPCQGSATCV-NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQ 120
Query: 119 HGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPG--- 175
HG C C CP GYAG CE++ DECAS+PC +G C DG+ + C C PG
Sbjct: 121 HGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQG 180
Query: 176 -----------------------------------YGGTRCQLDLDECQSQPCAHGGTCH 200
Y G C+L++DEC SQPC +G TC
Sbjct: 181 RHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQ 240
Query: 201 DLVNGFRCDCA--------------------------------------GTGYEGTHCER 222
D + + CDCA G+G+ GTHCE
Sbjct: 241 DALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCET 300
Query: 223 EVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDP 282
+ C S PC +NA+C + + ++ C CWPGY+G CE+D +EC S+PCQ G C++ S
Sbjct: 301 LMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSE 360
Query: 283 ALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGF 342
YG + P +FS+ A+G++C C PGF G C +V+EC+S PC NGG C++LP +
Sbjct: 361 KQYGRI-TGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNY 419
Query: 343 QCHCP------DGYAGPTCEEDVDECLSDPCLHGGTC----SDTVAGYICRCPETWGGRD 392
CHCP Y G C + + C CL+ GTC D G+ C CP
Sbjct: 420 TCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCP------- 472
Query: 393 CSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSVMAGSPIQAS 452
+G G C +A T FE +V T G C
Sbjct: 473 -----SGYTGSLCEIATTL--SFEGDGFLWVKSGSVTTKGSVC----------------- 508
Query: 453 VPAGGPLGLALRFRTTLPAGTLATRNDTKESLELALVAATLQATLWSYSTTVLVLRLPDL 512
+ALRF+T P L R++ ++L L++ + ++ + + ++L +
Sbjct: 509 -------NIALRFQTVQPMALLLFRSNRDVFVKLELLSGYIHLSIQVNNQSKVLLFISH- 560
Query: 513 ALNDGHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALASTASATP--------LPA 564
+DG WH VEV+ A + L L + C + C+A P L S S LP
Sbjct: 561 NTSDGEWHFVEVIFAEA-VTLTLIDDSCKEK-CIAKAPTPLESDQSICAFQNSFLGGLPV 618
Query: 565 GISSAQL---------GDATFAGCLQDVRVDGHLLLPEDLGE----NVLLGCERREQCRP 611
G++S + +F GCLQD+++D + + E++ NV GC R++ C
Sbjct: 619 GMTSNGVALLNFYNMPSTPSFVGCLQDIKIDWNHITLENISSGSSLNVKAGCVRKDWCES 678
Query: 612 LPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIPAATFGLGGAPSSASFLLQELPGPNLT 671
PC G C++LW ++CDC RP+ GP C E A FG + F L E G ++
Sbjct: 679 QPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYVIFTLDESYGDTIS 738
Query: 672 VSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPGRWDDGLRHLVML 731
+S +RT + +GLLL N + + V+L GR+ P SP +V+ +DG HL+ L
Sbjct: 739 LSMFVRTLQPSGLLLALENSTYQYIRVWLERGRLAMLTPNSPKLVVKFVLNDGNVHLISL 798
Query: 732 SFGPDQLQ------------------DLGQHVHVGGRLLAADSQPWGGPFRGCLQDLRLD 773
P +++ + G +++GG +++ GG F+GC+QD+RL+
Sbjct: 799 KIKPYKIELYQSSQNLGFISASTWKIEKGDVIYIGGLPDKQETELNGGFFKGCIQDVRLN 858
Query: 774 GCHLPFFPLPLDNSSQPSELGGRQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTC 833
+L FFP P +N+S L N+T GC ++ C +PC NGG C W+DF C+C
Sbjct: 859 NQNLEFFPNPTNNASLNPVL-----VNVTQGCAGDNSCKSNPCHNGGVCHSRWDDFSCSC 913
Query: 834 PANFTGPTCAQQLWCPGQPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGHNASSGRLL 893
PA +G C + WC PC A C+ V GF C+A A F N + R L
Sbjct: 914 PALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFECIANAVFNGQSGQILFRSNGNITREL 973
Query: 894 GGLSLAFRTRDSEAWLLRAAAGALEGVWLAVRNGSLAGGVRGGHGLPGAVLPIPG-PRVA 952
++ FRTRD+ +L A E + +++++ L ++ G+ +L + V
Sbjct: 974 TNITFGFRTRDANVIILHAEKEP-EFLNISIQDSRLFFQLQSGNSF--YMLSLTSLQSVN 1030
Query: 953 DGAWHRVRLAMERPAATTSRWLLWLDGAATPVALRGLASDLGFLQG-----PGAVRILLA 1007
DG WH V L+M P + TSRW + +D V L FL+ G I
Sbjct: 1031 DGTWHEVTLSMTDPLSQTSRWQMEVDNETPFVTSTIATGSLNFLKDNTDIYVGDRAIDNI 1090
Query: 1008 ENFTGCLGRVALGGLPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLH 1067
+ GCL + +GG+ L G +E T + + GC VC +PCLH
Sbjct: 1091 KGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGCLQLNVCNSNPCLH 1150
Query: 1068 DGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGP 1127
G C D++ ++ C+C GW G CE ++D C S PC G C + C C PG+ G
Sbjct: 1151 GGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRV-AAYHCTCEPGYTGV 1209
Query: 1128 RCRLPV---------------------------------------PSKEC---SLNVTCL 1145
C + + PS C N+TC
Sbjct: 1210 NCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCY 1269
Query: 1146 DGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSG 1205
+G C C C G G+ C+ C ++PC+NGG C+ +C+C+ F+G
Sbjct: 1270 NGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAG 1329
Query: 1206 QFCEVAKGLPLPLPFPLLEVAVPAACACLLLLLLGLLSGILAARKRRQSEGTYSPSQQEV 1265
+ CEV L L + A LL+LLL +++ ++ + K R ++GTYSPS+QE
Sbjct: 1330 ERCEV--DLADDLISDIFTTIGSVTVALLLILLLAIVASVVTSNK-RATQGTYSPSRQEK 1386
Query: 1266 AGARLEMDSVLKVPPEERLI 1285
G+R+EM +++ P ERLI
Sbjct: 1387 EGSRVEMWNLMPPPAMERLI 1406
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 359 bits (922), Expect = 8e-99
Identities = 173/428 (40%), Positives = 227/428 (53%), Gaps = 41/428 (9%)
Query: 41 ACASDPCAPGTECQA---------TESGGYTCGP-----MEPRGCATQPCHHGALCVPQG 86
AC S+PC G+ C T GYT GP ++ PC H C+
Sbjct: 375 ACISNPCNEGSNCDTNPVNGKAICTCPSGYT-GPACSQDVDECSLGANPCEHAGKCINT- 432
Query: 87 PDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME 146
F C C+ G+ GPRCE+D++EC S PC + ATC + ++C C GY GV CE+
Sbjct: 433 --LGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVN 490
Query: 147 VDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF 206
DECAS+PCLH G CLD + F+C C G+ G CQ D+DEC S PC +G C D N +
Sbjct: 491 TDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTY 550
Query: 207 RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECA 266
C C GY GTHCE ++ EC PC H SC +G+ +F CLC PGY+G CE + +EC+
Sbjct: 551 TCVCT-EGYTGTHCEVDIDECDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNINECS 608
Query: 267 SSPCQHGGRCLQRSDPALYGGVQ--------------AAFP--GAFSFRHAAGFLCHCPP 310
S PC+HGG C R + L ++ A+ P G+ C C P
Sbjct: 609 SQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEP 668
Query: 311 GFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHG 370
G+ G+ C + +DECA PC NGG C+D NGF C CP+GY PTC +V+EC S+PC+HG
Sbjct: 669 GYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHG 728
Query: 371 GTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGT 430
C D++ GY C C W G +C + C+ + C TC + YVC C G
Sbjct: 729 A-CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTC----KDMTSGYVCTCREGF 783
Query: 431 HGPFCGQN 438
GP C N
Sbjct: 784 SGPNCQTN 791
Score = 344 bits (883), Expect = 3e-94
Identities = 211/662 (31%), Positives = 285/662 (43%), Gaps = 108/662 (16%)
Query: 42 CASDPCAPGTECQATESGGYTCGPMEP----------RGCATQPCHHGALCVPQGPDPTG 91
CAS+PC C + GY C + P CA PC +G C Q D
Sbjct: 795 CASNPCLNQGTC-IDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGEC-RQSEDYES 852
Query: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
F C C G+QG CE+DI+EC PC HGA+C+N Y CHC GY+G CE ++D+C
Sbjct: 853 FSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCR 912
Query: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA 211
PC +GGSC DG+ + C C PG+ GT C+ D++EC S PC +G C D V+ + C C
Sbjct: 913 PNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCP 972
Query: 212 GTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQ 271
G+ G HCE +C + C + +C++G+ SF CLC PG++G C+ D +EC S PC
Sbjct: 973 -AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCL 1031
Query: 272 HGGRC------LQRSDPALYGGVQA-----------AFPGAFSFRHAAGFLCHCPPGFEG 314
HGG C + + P Y G G ++ + C CP G+ G
Sbjct: 1032 HGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTG 1091
Query: 315 ADCGVEVDEC----------ASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLS 364
C V C +R C +GG C D N C C GY G CE+ VDEC
Sbjct: 1092 LYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSP 1151
Query: 365 DPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVC 424
PC +G TC+D + GY C+C + G +CS ++ C H C TC+ + ++Y C
Sbjct: 1152 SPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDL----PNTYKC 1207
Query: 425 HCPPGTHGPFCGQNTTFSVMAGSPIQASVPA---GGPLGLALRFRTTLPAGTLATR--ND 479
CP GT G C N P+ S G + + T P G + R D
Sbjct: 1208 SCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGD 1267
Query: 480 TKESLELALVAATLQATLWSYSTTVLVLRLPDL--ALNDGH-WHQVEVVLHLATLELRLW 536
E L A T V R+ D GH + E V++
Sbjct: 1268 VNECLSNPCDAR---------GTQNCVQRVNDFHCECRAGHTGRRCESVIN--------- 1309
Query: 537 HEGCPARLCVASGPVALASTAS---ATPLPAGISSAQLGDATFAGCLQDVRVDGHLLLPE 593
GC + C G A+AS + PAG A C D R
Sbjct: 1310 --GCKGKPCKNGGTCAVASNTARGFICKCPAGFEGAT--------CENDART-------- 1351
Query: 594 DLGENVLLGCERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIPAATFGLGG 653
C L C++GG+C+ C C P GP C + PA++ LGG
Sbjct: 1352 ---------------CGSLRCLNGGTCISGPRSPTCLCLGPFTGPEC--QFPASSPCLGG 1394
Query: 654 AP 655
P
Sbjct: 1395 NP 1396
Score = 333 bits (854), Expect = 6e-91
Identities = 159/429 (37%), Positives = 224/429 (52%), Gaps = 53/429 (12%)
Query: 42 CASDPCAPGTECQATESGGYTCGPM----------EPRGCATQPCHHGALCVPQGPDPTG 91
C S+PC C + G + C M CA+ PC H C+ + +
Sbjct: 456 CVSNPCQNDATC-LDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINE--- 511
Query: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
F+C C GF G C+ D+DECAS PC +GA C + + Y C C GY G CE+++DEC
Sbjct: 512 FQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECD 571
Query: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA 211
PC H GSC DGV +F C+C PGY G C+ +++EC SQPC HGGTC D N + C C
Sbjct: 572 PDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCL 630
Query: 212 GTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQ 271
G G +CE + +CAS+PC+ + +CL+ + + C C PGY+G +C ++ DECA +PC
Sbjct: 631 -KGTTGPNCEINLDDCASSPCD-SGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCH 688
Query: 272 HGGRCLQ-------------------------RSDPALYGGVQAAFPGAFSFRHAAGFLC 306
+GG C S+P ++G + + G + C
Sbjct: 689 NGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNG---------YKC 739
Query: 307 HCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDP 366
C PG+ G +C + +EC S PC+NGG C+D+ +G+ C C +G++GP C+ +++EC S+P
Sbjct: 740 DCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNP 799
Query: 367 CLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHC 426
CL+ GTC D VAGY C C + G C V L C C C S+ C C
Sbjct: 800 CLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQ--SEDYESFSCVC 857
Query: 427 PPGTHGPFC 435
P G G C
Sbjct: 858 PTGWQGQTC 866
Score = 290 bits (743), Expect = 5e-78
Identities = 155/437 (35%), Positives = 199/437 (45%), Gaps = 63/437 (14%)
Query: 32 GTVPSEPPSACASDPCAPGTEC-QATESGGYTCGPMEPRG------------CATQPCHH 78
GT E + CASDPC G C +S TC P G C C +
Sbjct: 939 GTFCEEDINECASDPCRNGANCTDCVDSYTCTC----PAGFSGIHCENNTPDCTESSCFN 994
Query: 79 GALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGY 138
G CV F C C PGF G C+ D++EC S+PC HG TC++ Y C CP GY
Sbjct: 995 GGTCV---DGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGY 1051
Query: 139 AGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQ--------- 189
G C+ V C S+PC +GG C +RC C G+ G C + C+
Sbjct: 1052 TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVD 1111
Query: 190 -SQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCL 248
++ C HGG C D N C C GY G++CE V EC+ +PC++ A+C + LG + C
Sbjct: 1112 VARLCQHGGLCVDAGNTHHCRCQ-AGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCK 1170
Query: 249 CWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHC 308
C GY G C + DEC S PCQ+GG CL P + C C
Sbjct: 1171 CVAGYHGVNCSEEIDECLSHPCQNGGTCLD-------------LPNTYK--------CSC 1209
Query: 309 PPGFEGADCGVEVDEC--------ASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVD 360
P G +G C + VD+C S C N G C D G+ C CP G+ G CE DV+
Sbjct: 1210 PRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVN 1269
Query: 361 ECLSDPCLHGGT--CSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESG 418
ECLS+PC GT C V + C C GR C + GC+G C TC + +
Sbjct: 1270 ECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTC-AVASNT 1328
Query: 419 VHSYVCHCPPGTHGPFC 435
++C CP G G C
Sbjct: 1329 ARGFICKCPAGFEGATC 1345
Score = 283 bits (723), Expect = 1e-75
Identities = 155/451 (34%), Positives = 220/451 (48%), Gaps = 39/451 (8%)
Query: 11 PQALASVLLLLLWAPALSLLAGTVPSEPPSACASD-PCAPGTECQATESGGYTCGP--ME 67
P LA +L L L PAL+ G S+P C + C +A GG GP +
Sbjct: 2 PPLLAPLLCLAL-LPALAA-RGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQD 59
Query: 68 PRGCATQPCHHGALC-VPQGPDPTGFRCYCVPGFQGPRCELDIDE-CASRPCHHGATCRN 125
P C + PC + C V + C C GF GP C +D C + PC +G TC
Sbjct: 60 PNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDL 119
Query: 126 LA-DRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLD 184
L Y+C CP G++G +C+ + D CAS PC +GG CL S+ C C P + G C+ D
Sbjct: 120 LTLTEYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQD 178
Query: 185 LDECQSQP--CAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLE-G 241
++EC +P C HGGTCH+ V +RC C T + G +CER + C+ +PC++ +C G
Sbjct: 179 VNECGQKPGLCRHGGTCHNEVGSYRCVCRAT-HTGPNCERPYVPCSPSPCQNGGTCRPTG 237
Query: 242 LGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHA 301
+ C C PG++G+ CE + D+C + C++GG C+ GV
Sbjct: 238 DVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVD--------GVNT----------- 278
Query: 302 AGFLCHCPPGFEGADCGVEVDECASRP--CLNGGHCQDLPNGFQCHCPDGYAGPTCEEDV 359
+ C CPP + G C +VDEC P C NGG C + G+ C C +G+ G C E++
Sbjct: 279 --YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENI 336
Query: 360 DECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGV 419
D+C S C HG TC D VA + C CP G C + C + C + C +G
Sbjct: 337 DDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLN-DACISNPCNEGSNCDTNPVNG- 394
Query: 420 HSYVCHCPPGTHGPFCGQNTTFSVMAGSPIQ 450
+C CP G GP C Q+ + +P +
Sbjct: 395 -KAICTCPSGYTGPACSQDVDECSLGANPCE 424
Score = 272 bits (695), Expect = 2e-72
Identities = 150/448 (33%), Positives = 204/448 (45%), Gaps = 59/448 (13%)
Query: 37 EPPSACASDPCAPGTECQATESGG---YTC-------GPM----EPRGCATQPCHHGALC 82
+ P+ C S PC C + G Y C GP+ C T PC +G C
Sbjct: 58 QDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTC 117
Query: 83 VPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVT 142
T ++C C PG+ G C+ D CAS PC +G C Y CHCP + G T
Sbjct: 118 --DLLTLTEYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASYICHCPPSFHGPT 174
Query: 143 CEMEVDECASAP--CLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCH 200
C +V+EC P C HGG+C + VGS+RCVC + G C+ C PC +GGTC
Sbjct: 175 CRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCR 234
Query: 201 DLVN-GFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCE 259
+ C C G+ G +CE + +C C++ +C++G+ ++ C C P ++G+ C
Sbjct: 235 PTGDVTHECACL-PGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCT 293
Query: 260 VDEDECASSP--CQHGGRCLQRSDPALYGGVQ----------------------AAFPGA 295
D DEC P CQ+GG C +GG A F GA
Sbjct: 294 EDVDECQLMPNACQNGGTCHNT-----HGGYNCVCVNGWTGEDCSENIDDCASAACFHGA 348
Query: 296 FSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLP-NGFQ-CHCPDGYAGP 353
A F C CP G G C + D C S PC G +C P NG C CP GY GP
Sbjct: 349 TCHDRVASFYCECPHGRTGLLCHLN-DACISNPCNEGSNCDTNPVNGKAICTCPSGYTGP 407
Query: 354 TCEEDVDECL--SDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATC 411
C +DVDEC ++PC H G C +T+ + C+C + + G C + + C + C ATC
Sbjct: 408 ACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATC 467
Query: 412 IPIFESGVHSYVCHCPPGTHGPFCGQNT 439
+ + + C C PG G C NT
Sbjct: 468 L----DQIGEFQCICMPGYEGVHCEVNT 491
Score = 246 bits (627), Expect = 1e-64
Identities = 136/387 (35%), Positives = 178/387 (45%), Gaps = 55/387 (14%)
Query: 42 CASDPCAPGTECQATES-----------GGYTCGPMEPRGCATQP--------CHHGALC 82
C S PC G +C T + G Y P A Q C HG LC
Sbjct: 1063 CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLC 1122
Query: 83 VPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVT 142
V G C C G+ G CE +DEC+ PC +GATC + Y C C GY GV
Sbjct: 1123 VDAG---NTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVN 1179
Query: 143 CEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDEC--------QSQPCA 194
C E+DEC S PC +GG+CLD +++C C G G C++++D+C +S C
Sbjct: 1180 CSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCF 1239
Query: 195 HGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNAS--CLEGLGSFRCLCWPG 252
+ GTC D V G+ C C G+ G CE +V EC S PC+ + C++ + F C C G
Sbjct: 1240 NNGTCVDQVGGYSCTCP-PGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAG 1298
Query: 253 YSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGF 312
++G CE + C PC++GG C S+ A GF+C CP GF
Sbjct: 1299 HTGRRCESVINGCKGKPCKNGGTCAVASNTA------------------RGFICKCPAGF 1340
Query: 313 EGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDE-CL-SDPCLHG 370
EGA C + C S CLNGG C P C C + GP C+ CL +PC +
Sbjct: 1341 EGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQ 1400
Query: 371 GTCSDTVAG--YICRCPETWGGRDCSV 395
GTC T Y C CP + G C +
Sbjct: 1401 GTCEPTSESPFYRCLCPAKFNGLLCHI 1427
Score = 119 bits (299), Expect = 1e-26
Identities = 57/160 (35%), Positives = 80/160 (50%), Gaps = 4/160 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
CA +PC + G C D + F C C G+ P C + V+ C+S PC G C +G ++C
Sbjct: 682 CAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNG-YKCD 740
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
C PG+ G C + + EC N C++G C+ + C+C EG +G CQ C +
Sbjct: 741 CDPGWSGTNC--DINNNECESN-PCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECAS 797
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGLPLPLP 1219
NPCLN GTC +C C ++G CEV P P
Sbjct: 798 NPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSP 837
Score = 118 bits (296), Expect = 3e-26
Identities = 56/153 (36%), Positives = 74/153 (48%), Gaps = 6/153 (3%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C +PC+H GACRD + + C C PGW G C+ + + C S PC G + C
Sbjct: 720 CNSNPCVH-GACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCT 778
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
C GF GP C+ + EC+ N CL+ C C+CL G C+V PC
Sbjct: 779 CREGFSGPNCQTNI--NECASN-PCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAP 835
Query: 1180 NPCLNGGTCRAAGGVS--ECICNARFSGQFCEV 1210
+PC NGG CR + C+C + GQ CEV
Sbjct: 836 SPCRNGGECRQSEDYESFSCVCPTGWQGQTCEV 868
Score = 118 bits (295), Expect = 4e-26
Identities = 61/153 (39%), Positives = 73/153 (47%), Gaps = 6/153 (3%)
Query: 1060 CAPSPCLHDGACRDL-FDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFEC 1118
C +PC + G C L + C C PGW G C+ DPC S PCA G + + C
Sbjct: 106 CLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASYIC 164
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNV-TCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
CPP F GP CR V EC C G C + C C G C+ P +PC
Sbjct: 165 HCPPSFHGPTCRQDV--NECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPC 222
Query: 1178 EANPCLNGGTCRAAGGVS-ECICNARFSGQFCE 1209
+PC NGGTCR G V+ EC C F+GQ CE
Sbjct: 223 SPSPCQNGGTCRPTGDVTHECACLPGFTGQNCE 255
Score = 115 bits (289), Expect = 2e-25
Identities = 54/152 (35%), Positives = 72/152 (47%), Gaps = 5/152 (3%)
Query: 1060 CAPSPCLHDGACRDL--FDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFE 1117
CAPSPC + G CR +++F+C C GW+G CE ++ C +PC G + G +
Sbjct: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR 892
Query: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
C C G+ G C + +C N C +G C G A C CL G G C+ C
Sbjct: 893 CHCQAGYSGRNCETDI--DDCRPN-PCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINEC 949
Query: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
++PC NG C C C A FSG CE
Sbjct: 950 ASDPCRNGANCTDCVDSYTCTCPAGFSGIHCE 981
Score = 115 bits (288), Expect = 3e-25
Identities = 57/150 (38%), Positives = 71/150 (47%), Gaps = 5/150 (3%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
CA SPC G C D D + CAC PG+ G C ++D C PC G F CR
Sbjct: 645 CASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCR 703
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
CP G+ P C V EC+ N C+ G+ C C C G +G C + CE+
Sbjct: 704 CPEGYHDPTCLSEV--NECNSN-PCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECES 759
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
NPC+NGGTC+ C C FSG C+
Sbjct: 760 NPCVNGGTCKDMTSGYVCTCREGFSGPNCQ 789
Score = 115 bits (287), Expect = 4e-25
Identities = 56/151 (37%), Positives = 78/151 (51%), Gaps = 5/151 (3%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C+ PC H G C+D +A+ C C G GP CE ++D C S+PC G C DG +EC
Sbjct: 607 CSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDG-YECA 665
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
C PG+ G C + + EC+ N C +G CE G C C EG C C +
Sbjct: 666 CEPGYTGSMCNINI--DECAGN-PCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNS 722
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
NPC++ G CR + +C C+ +SG C++
Sbjct: 723 NPCVH-GACRDSLNGYKCDCDPGWSGTNCDI 752
Score = 114 bits (285), Expect = 6e-25
Identities = 55/151 (36%), Positives = 75/151 (49%), Gaps = 6/151 (3%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTHPDGRFEC 1118
C +PC +D C D F C C PG+EG CE + D C S+PC GRC F+C
Sbjct: 456 CVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRC-LDKINEFQC 514
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
CP GF G C+ V EC+ + C +G+ C G C C EG G C+V C+
Sbjct: 515 ECPTGFTGHLCQYDV--DECA-STPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECD 571
Query: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
+PC + G+C+ C+C ++G CE
Sbjct: 572 PDPC-HYGSCKDGVATFTCLCRPGYTGHHCE 601
Score = 111 bits (278), Expect = 4e-24
Identities = 52/150 (34%), Positives = 72/150 (48%), Gaps = 3/150 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C P+PC + G+C D + C C PG+ G CE ++ C S PC G T + C
Sbjct: 911 CRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCT 970
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
CP GF G C P +C+ +C +G C G + C C G G CQ C++
Sbjct: 971 CPAGFSGIHCENNTP--DCT-ESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDS 1027
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
PCL+GGTC+ G C C ++G C+
Sbjct: 1028 QPCLHGGTCQDGCGSYRCTCPQGYTGPNCQ 1057
Score = 108 bits (271), Expect = 3e-23
Identities = 55/162 (33%), Positives = 72/162 (44%), Gaps = 13/162 (8%)
Query: 1058 PVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFE 1117
P C S C + G C D ++F C C PG+ G C+ V+ C S PC G G +
Sbjct: 985 PDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYR 1044
Query: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
C CP G+ GP C+ V + S C +G C C C G G C VP++ C
Sbjct: 1045 CTCPQGYTGPNCQNLVHWCDSS---PCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSC 1101
Query: 1178 E----------ANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
E A C +GG C AG C C A ++G +CE
Sbjct: 1102 EVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCE 1143
Score = 108 bits (269), Expect = 4e-23
Identities = 51/151 (33%), Positives = 71/151 (47%), Gaps = 3/151 (1%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
CA PC + C D D++ C C G+ G CE + C + C G F C
Sbjct: 949 CASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCL 1008
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
CPPGF G C+ V EC + CL G C+ G + C+C +G G CQ C++
Sbjct: 1009 CPPGFTGSYCQHDV--NECD-SQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDS 1065
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
+PC NGG C C C + ++G +C+V
Sbjct: 1066 SPCKNGGKCWQTHTQYRCECPSGWTGLYCDV 1096
Score = 105 bits (261), Expect = 4e-22
Identities = 54/152 (35%), Positives = 72/152 (47%), Gaps = 6/152 (3%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
CA SPCLH+G C D + F C C G+ G C+ VD C S PC G +C P+ + C
Sbjct: 494 CASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPN-TYTC 552
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
C G+ G C + + EC + C GS C+ G C C G G C+ C
Sbjct: 553 VCTEGYTGTHCEVDID--ECDPD-PCHYGS-CKDGVATFTCLCRPGYTGHHCETNINECS 608
Query: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
+ PC +GGTC+ C C +G CE+
Sbjct: 609 SQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEI 640
Score = 104 bits (259), Expect = 6e-22
Identities = 51/148 (34%), Positives = 65/148 (43%), Gaps = 3/148 (2%)
Query: 1063 SPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPP 1122
+PC H G C + +F C C G+ GPRCE V+ C S PC G F+C C P
Sbjct: 421 NPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMP 480
Query: 1123 GFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPC 1182
G+ G C V + EC+ + CL C C C G G CQ C + PC
Sbjct: 481 GYEGVHCE--VNTDECA-SSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPC 537
Query: 1183 LNGGTCRAAGGVSECICNARFSGQFCEV 1210
NG C C+C ++G CEV
Sbjct: 538 KNGAKCLDGPNTYTCVCTEGYTGTHCEV 565
Score = 100 bits (250), Expect = 7e-21
Identities = 48/150 (32%), Positives = 68/150 (45%), Gaps = 3/150 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C SPC H +C++ + C C G+ G CE +D C PC G T C
Sbjct: 873 CVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCD 932
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
C PGF G C + EC+ + C +G+ C + C+C G +G C+ T C
Sbjct: 933 CLPGFRGTFCEEDI--NECASD-PCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTE 989
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
+ C NGGTC C+C F+G +C+
Sbjct: 990 SSCFNGGTCVDGINSFTCLCPPGFTGSYCQ 1019
Score = 100 bits (249), Expect = 9e-21
Identities = 56/189 (29%), Positives = 73/189 (38%), Gaps = 42/189 (22%)
Query: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG--------------- 1106
P+ C + G C + + C C GW G C ++D C SA C G
Sbjct: 303 PNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECP 362
Query: 1107 -----------------------RCHTHP-DGRFECRCPPGFGGPRCRLPVPSKECSLNV 1142
C T+P +G+ C CP G+ GP C V ECSL
Sbjct: 363 HGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDV--DECSLGA 420
Query: 1143 T-CLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNA 1201
C C + C CL+G G RC++ C +NPC N TC G +CIC
Sbjct: 421 NPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMP 480
Query: 1202 RFSGQFCEV 1210
+ G CEV
Sbjct: 481 GYEGVHCEV 489
Score = 98.2 bits (243), Expect = 4e-20
Identities = 55/160 (34%), Positives = 70/160 (43%), Gaps = 10/160 (6%)
Query: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAP--CARG-RCHT 1110
C+ A CA +PC + G C ++ C C P + GP C V+ C P C G CH
Sbjct: 138 CQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHN 197
Query: 1111 HPDGRFECRCPPGFGGPRCRLP-VPSKECSLNVTCLDGSPCEG-GSPAANCSCLEGLAGQ 1168
G + C C GP C P VP CS + C +G C G C+CL G GQ
Sbjct: 198 EV-GSYRCVCRATHTGPNCERPYVP---CSPS-PCQNGGTCRPTGDVTHECACLPGFTGQ 252
Query: 1169 RCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
C+ C N C NGG C C C ++GQ+C
Sbjct: 253 NCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYC 292
Score = 97.8 bits (242), Expect = 6e-20
Identities = 67/221 (30%), Positives = 88/221 (39%), Gaps = 55/221 (24%)
Query: 1058 PVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPC-ARG---------- 1106
PV C ++G C D ++C C PG+ G RCE V+ C S PC ARG
Sbjct: 1231 PVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVND 1290
Query: 1107 ---RCHTHPDGR-----------------------------FECRCPPGFGGPRCRLPVP 1134
C GR F C+CP GF G C
Sbjct: 1291 FHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEND-- 1348
Query: 1135 SKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVP-TLPC-EANPCLNGGTCR--A 1190
++ C ++ CL+G C G + C CL G CQ P + PC NPC N GTC +
Sbjct: 1349 ARTCG-SLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTS 1407
Query: 1191 AGGVSECICNARFSGQFCEV-----AKGLPLPLPFPLLEVA 1226
C+C A+F+G C + G +P PL+E A
Sbjct: 1408 ESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEA 1448
Score = 97.4 bits (241), Expect = 8e-20
Identities = 58/198 (29%), Positives = 75/198 (37%), Gaps = 48/198 (24%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C+PSPC + C D ++C C G+ G C +D C S PC G ++C
Sbjct: 1149 CSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCS 1208
Query: 1120 CPPGFGGPRCRLPVP-----------SKECSLNVTCLD--------------GSPCEG-- 1152
CP G G C + V S +C N TC+D G CEG
Sbjct: 1209 CPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDV 1268
Query: 1153 ----GSPA--------------ANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGV 1194
+P +C C G G+RC+ C+ PC NGGTC A
Sbjct: 1269 NECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNT 1328
Query: 1195 SE---CICNARFSGQFCE 1209
+ C C A F G CE
Sbjct: 1329 ARGFICKCPAGFEGATCE 1346
Score = 93.6 bits (231), Expect = 1e-18
Identities = 54/196 (27%), Positives = 73/196 (37%), Gaps = 45/196 (22%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C PCLH G C+D ++ C C G+ GP C+ V C S+PC G ++ C
Sbjct: 1025 CDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCE 1084
Query: 1120 CPPGFGGPRCRLPVPSKE-------------CSLNVTCLDG------------------- 1147
CP G+ G C +P S E C C+D
Sbjct: 1085 CPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCED 1144
Query: 1148 -------SPCEGGSPAAN------CSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGV 1194
SPC+ G+ + C C+ G G C C ++PC NGGTC
Sbjct: 1145 LVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNT 1204
Query: 1195 SECICNARFSGQFCEV 1210
+C C G CE+
Sbjct: 1205 YKCSCPRGTQGVHCEI 1220
Score = 91.7 bits (226), Expect = 4e-18
Identities = 59/166 (35%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query: 1050 PILGCRGAPVCAPSP-CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GR 1107
P L RG P CL+ G C AC CG + GPRC+ +PC S PC G
Sbjct: 15 PALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGT 73
Query: 1108 CHTHPDGR----FECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGS-PAANCSCL 1162
CH D R + C C GF GP C P+ + L C +G C+ + C C
Sbjct: 74 CHV-VDRRGVADYACSCALGFSGPLCLTPLDN--ACLTNPCRNGGTCDLLTLTEYKCRCP 130
Query: 1163 EGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
G +G+ CQ PC +NPC NGG C C C F G C
Sbjct: 131 PGWSGKSCQQAD-PCASNPCANGGQCLPFEASYICHCPPSFHGPTC 175
Score = 88.2 bits (217), Expect = 5e-17
Identities = 51/153 (33%), Positives = 64/153 (41%), Gaps = 11/153 (7%)
Query: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
C H G C D + C C G+ G CE VD C +PC G T G + C+C G+
Sbjct: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY 1175
Query: 1125 GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQV-------PTLPC 1177
G C + EC L+ C +G C CSC G G C++ P P
Sbjct: 1176 HGVNCSEEI--DEC-LSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPV 1232
Query: 1178 EANP-CLNGGTCRAAGGVSECICNARFSGQFCE 1209
+P C N GTC G C C F G+ CE
Sbjct: 1233 SRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE 1265
Score = 79.3 bits (194), Expect = 2e-14
Identities = 48/155 (30%), Positives = 66/155 (42%), Gaps = 12/155 (7%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCA---RGRCH-THPDGR 1115
C + C + GAC D + + C C P W G C VD C P A G CH TH G
Sbjct: 261 CPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTH--GG 318
Query: 1116 FECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTL 1175
+ C C G+ G C + +C+ + C G+ C + C C G G C +
Sbjct: 319 YNCVCVNGWTGEDCSENI--DDCA-SAACFHGATCHDRVASFYCECPHGRTGLLCHLND- 374
Query: 1176 PCEANPCLNGGTC--RAAGGVSECICNARFSGQFC 1208
C +NPC G C G + C C + ++G C
Sbjct: 375 ACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPAC 409
Score = 70.9 bits (172), Expect = 8e-12
Identities = 74/303 (24%), Positives = 104/303 (34%), Gaps = 89/303 (29%)
Query: 42 CASDPC-APGT------------ECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPD 88
C S+PC A GT EC+A +G + GC +PC +G C
Sbjct: 1271 CLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVIN--GCKGKPCKNGGTCAVASNT 1328
Query: 89 PTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVD 148
GF C C GF+G CE D C S C +G TC + C C + G C+
Sbjct: 1329 ARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFP-- 1386
Query: 149 ECASAPCLHGGSCLDGVGS--------FRCVCAPGYGGTRCQL----------------- 183
AS+PCL G C + +RC+C + G C +
Sbjct: 1387 --ASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPL 1444
Query: 184 -----DLDECQ--------SQPCAH------GGTCHDLVNG------------------- 205
+L ECQ S C + GG C N
Sbjct: 1445 IEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGH 1504
Query: 206 --FRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDED 263
+C+ AG ++G C+R +C ++ C + C G + CE D
Sbjct: 1505 CDSQCNSAGCLFDGFDCQRAEGQCNPL---YDQYCKDHFSDGH--CDQGCNSAECEWDGL 1559
Query: 264 ECA 266
+CA
Sbjct: 1560 DCA 1562
Score = 58.5 bits (140), Expect = 4e-08
Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 9/80 (11%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
C+ CFNGGTC+ N F C CP FTG C + C QPCL TC++ + C
Sbjct: 987 CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCT 1046
Query: 870 AEATFREGPPAAFSGHNASS 889
P ++G N +
Sbjct: 1047 C--------PQGYTGPNCQN 1058
Score = 57.4 bits (137), Expect = 9e-08
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
V+ D C+ PC + G CL N+F C CP FTG C + C PC A C + P+
Sbjct: 489 VNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPN 548
Query: 865 GFVCV 869
+ CV
Sbjct: 549 TYTCV 553
Score = 57.4 bits (137), Expect = 9e-08
Identities = 25/71 (35%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Query: 799 WNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPA 857
W+ T ++ + C +PC NGGTC + + CTC F+GP C + C PCL
Sbjct: 745 WSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQG 804
Query: 858 TCEEVPDGFVC 868
TC + G+ C
Sbjct: 805 TCIDDVAGYKC 815
Score = 55.8 bits (133), Expect = 3e-07
Identities = 28/72 (38%), Positives = 34/72 (47%), Gaps = 3/72 (4%)
Query: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQP---CLPPATCEE 861
C D C+ +PC NGG CL + C CP +F GPTC Q + GQ C TC
Sbjct: 138 CQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHN 197
Query: 862 VPDGFVCVAEAT 873
+ CV AT
Sbjct: 198 EVGSYRCVCRAT 209
Score = 55.5 bits (132), Expect = 3e-07
Identities = 44/144 (30%), Positives = 59/144 (40%), Gaps = 19/144 (13%)
Query: 769 DLRLDGCHLPFFPLP-----LDNSSQPSELGGRQSWNLTAGCVSE------DMCSPDPCF 817
++ +D C+ P P+ +N + ++GG S G V E + C +PC
Sbjct: 1219 EINVDDCNPPVDPVSRSPKCFNNGTCVDQVGG-YSCTCPPGFVGERCEGDVNECLSNPCD 1277
Query: 818 NGGT--CLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATC---EEVPDGFVCVAE 871
GT C+ NDFHC C A TG C + C G+PC TC GF+C
Sbjct: 1278 ARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCP 1337
Query: 872 ATFREGPPAAFSGHNASSGRLLGG 895
A F EG S R L G
Sbjct: 1338 AGF-EGATCENDARTCGSLRCLNG 1360
Score = 53.9 bits (128), Expect = 1e-06
Identities = 27/77 (35%), Positives = 33/77 (42%), Gaps = 9/77 (11%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D C P+PC NGG+C N C C F G C + + C PC A C + D +
Sbjct: 909 DDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYT 968
Query: 868 CVAEATFREGPPAAFSG 884
C PA FSG
Sbjct: 969 CTC--------PAGFSG 977
Score = 53.5 bits (127), Expect = 1e-06
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D CSP PC NG TC + C C A + G C++++ C PC TC ++P+ +
Sbjct: 1147 DECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYK 1206
Query: 868 C 868
C
Sbjct: 1207 C 1207
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 808 EDMCSPDPCFNGGTC-LVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVPDGF 866
++ C +PC NGGTC L+T ++ C CP ++G +C Q C PC C +
Sbjct: 103 DNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASY 162
Query: 867 VCVAEATFREGP 878
+C +F GP
Sbjct: 163 ICHCPPSF-HGP 173
Score = 53.1 bits (126), Expect = 2e-06
Identities = 34/122 (27%), Positives = 47/122 (38%), Gaps = 46/122 (37%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL------------------- 846
++ D C+ +PC NGGTC N F C CP + PTC ++
Sbjct: 677 INIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNG 736
Query: 847 --------W-----------CPGQPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGHNA 887
W C PC+ TC+++ G+VC T REG FSG N
Sbjct: 737 YKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVC----TCREG----FSGPNC 788
Query: 888 SS 889
+
Sbjct: 789 QT 790
Score = 50.8 bits (120), Expect = 8e-06
Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
Query: 811 CSPDPCFNGGTCLVT--WNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
C+P PC NGG C + + F C CP + G TC + C PC A+C+ G+
Sbjct: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR 892
Query: 868 CVAEATF 874
C +A +
Sbjct: 893 CHCQAGY 899
Score = 49.7 bits (117), Expect = 2e-05
Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
++ D C+ PC + GTCL + + C C +TG C + C G PC TCE+ +
Sbjct: 640 INLDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGIN 698
Query: 865 GFVC 868
GF C
Sbjct: 699 GFTC 702
Score = 48.1 bits (113), Expect = 5e-05
Identities = 22/65 (33%), Positives = 29/65 (44%), Gaps = 1/65 (1%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
C+ DPC NG C + + CTCPA F+G C C C TC + + F C+
Sbjct: 949 CASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCL 1008
Query: 870 AEATF 874
F
Sbjct: 1009 CPPGF 1013
Score = 47.8 bits (112), Expect = 7e-05
Identities = 25/62 (40%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
CS PC +GGTC N + C C TGP C L C PC TC + DG+ C
Sbjct: 607 CSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPC-DSGTCLDKIDGYECA 665
Query: 870 AE 871
E
Sbjct: 666 CE 667
Score = 45.8 bits (107), Expect = 3e-04
Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 21/112 (18%)
Query: 775 CHLPFFPLPLDNSSQPSELGG--RQSWNLTAGCV------------SEDMCSPDPCFNGG 820
C P+ P S P + GG R + ++T C + D C + C NGG
Sbjct: 215 CERPYVPC----SPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGG 270
Query: 821 TCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQP--CLPPATCEEVPDGFVCV 869
C+ N ++C CP +TG C + + C P C TC G+ CV
Sbjct: 271 ACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCV 322
Score = 45.8 bits (107), Expect = 3e-04
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 809 DMCS--PDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDG 865
D CS +PC + G C+ T F C C +TGP C + C PC ATC +
Sbjct: 414 DECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGE 473
Query: 866 FVCV 869
F C+
Sbjct: 474 FQCI 477
Score = 45.1 bits (105), Expect = 4e-04
Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
V D C PDPC + G+C F C C +TG C + C QPC TC++ +
Sbjct: 565 VDIDECDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDN 623
Query: 865 GFVC 868
++C
Sbjct: 624 AYLC 627
Score = 45.1 bits (105), Expect = 4e-04
Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 1/60 (1%)
Query: 816 CFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCVAEATF 874
C +GG C+ N HC C A +TG C + C PC ATC + G+ C A +
Sbjct: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY 1175
Score = 45.1 bits (105), Expect = 4e-04
Identities = 32/109 (29%), Positives = 40/109 (36%), Gaps = 15/109 (13%)
Query: 781 PLPLDNSSQPSELGGRQSWNLTAG-----CVSE-DMCSPDPCFNGGTCLVTWNDFHCTCP 834
P P N + ++ G S AG C E D C PC NGGTCL N + C+CP
Sbjct: 1151 PSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCP 1210
Query: 835 ANFTGPTCAQQLWCPGQP---------CLPPATCEEVPDGFVCVAEATF 874
G C + P C TC + G+ C F
Sbjct: 1211 RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGF 1259
Score = 43.1 bits (100), Expect = 0.002
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLW-CPGQPCLPPATCEEVPD--GFV 867
C+ +PC N GTC+ + C C +TG TC L C PC C + D F
Sbjct: 795 CASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFS 854
Query: 868 CV 869
CV
Sbjct: 855 CV 856
Score = 43.1 bits (100), Expect = 0.002
Identities = 24/69 (34%), Positives = 28/69 (40%), Gaps = 5/69 (7%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCP---GQPCLPPATCEEVPDG-- 865
C C NGGTC+ C C FTGP C P G PC TCE +
Sbjct: 1352 CGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPF 1411
Query: 866 FVCVAEATF 874
+ C+ A F
Sbjct: 1412 YRCLCPAKF 1420
Score = 42.4 bits (98), Expect = 0.003
Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 6/62 (9%)
Query: 805 CVSEDMCSPDPCFNGGTCLVTWN----DFHCTCPANFTGPTCAQQL--WCPGQPCLPPAT 858
C + C PC N GTC V D+ C+C F+GP C L C PC T
Sbjct: 57 CQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGT 116
Query: 859 CE 860
C+
Sbjct: 117 CD 118
Score = 42.4 bits (98), Expect = 0.003
Identities = 31/111 (27%), Positives = 40/111 (36%), Gaps = 12/111 (10%)
Query: 759 WGGPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELGGRQSWNLTAGCVSEDM------CS 812
W G + C +D+ D C L P N G + G ED C+
Sbjct: 287 WTGQY--CTEDV--DECQL--MPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCA 340
Query: 813 PDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVP 863
CF+G TC F+C CP TG C C PC + C+ P
Sbjct: 341 SAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNP 391
Score = 42.0 bits (97), Expect = 0.004
Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 9/76 (11%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
C +PC N TCL +F C C + G C C PCL C + + F C
Sbjct: 456 CVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCE 515
Query: 870 AEATFREGPPAAFSGH 885
P F+GH
Sbjct: 516 C--------PTGFTGH 523
Score = 41.6 bits (96), Expect = 0.005
Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 5/43 (11%)
Query: 1167 GQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
G RC P CLNGG C AA G C+C F G C+
Sbjct: 21 GPRCSQP-----GETCLNGGKCEAANGTEACVCGGAFVGPRCQ 58
Score = 40.4 bits (93), Expect = 0.011
Identities = 13/42 (30%), Positives = 21/42 (50%)
Query: 603 CERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
C++ + C PC +GG C+ + C C GPTC ++
Sbjct: 138 CQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDV 179
Score = 40.4 bits (93), Expect = 0.011
Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 1/60 (1%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQ-QLWCPGQPCLPPATCEEVPD 864
V+E P C +GGTC + C C A TGP C + + C PC TC D
Sbjct: 179 VNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGD 238
Score = 39.7 bits (91), Expect = 0.019
Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D C+ PC NG CL N + C C +TG C + C PC +C++ F
Sbjct: 530 DECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPC-HYGSCKDGVATFT 588
Query: 868 CV 869
C+
Sbjct: 589 CL 590
Score = 39.3 bits (90), Expect = 0.025
Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 9/71 (12%)
Query: 805 CVSEDMCSPDPCFNGGTCLVTWNDFH----CTCPANFTGPTCAQ---QLWCPGQPCLPPA 857
C D C +PC G C N + CTCP+ +TGP C+Q + PC
Sbjct: 370 CHLNDACISNPCNEGSNC--DTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAG 427
Query: 858 TCEEVPDGFVC 868
C F C
Sbjct: 428 KCINTLGSFEC 438
Score = 39.3 bits (90), Expect = 0.025
Identities = 14/32 (43%), Positives = 17/32 (53%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC 842
C PC NGG C T + C CP+ +TG C
Sbjct: 1063 CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYC 1094
Score = 38.9 bits (89), Expect = 0.032
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
+C PCV+GG+C D+ + + C C GP C I
Sbjct: 756 ECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNI 792
Score = 38.1 bits (87), Expect = 0.055
Identities = 17/49 (34%), Positives = 18/49 (36%)
Query: 814 DPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEV 862
+ C NGG C C C F GP C C PC TC V
Sbjct: 29 ETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVV 77
Score = 37.7 bits (86), Expect = 0.071
Identities = 12/33 (36%), Positives = 21/33 (63%)
Query: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
+C PC++ G+C+D ++C+C P+ G TC
Sbjct: 794 ECASNPCLNQGTCIDDVAGYKCNCLLPYTGATC 826
Score = 37.4 bits (85), Expect = 0.093
Identities = 14/43 (32%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 603 CE-RREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
CE ++C PC+H G C+D F+C+C G C ++
Sbjct: 487 CEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDV 529
Score = 37.4 bits (85), Expect = 0.093
Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 15/81 (18%)
Query: 561 PLPAGISSAQLGDATFAGCLQDVRVDGHLLLPEDLGENVLLGCERR-EQCRPLPCVHGGS 619
P P S + G ATF CL GH CE +C PC HGG+
Sbjct: 572 PDPCHYGSCKDGVATFT-CLCRPGYTGH-------------HCETNINECSSQPCRHGGT 617
Query: 620 CVDLWTHFRCDCARPHRGPTC 640
C D + C C + GP C
Sbjct: 618 CQDRDNAYLCFCLKGTTGPNC 638
Score = 37.4 bits (85), Expect = 0.093
Identities = 14/38 (36%), Positives = 20/38 (52%)
Query: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
++C PC +GG+C D F C C + PTC E+
Sbjct: 680 DECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEV 717
Score = 35.4 bits (80), Expect = 0.35
Identities = 11/32 (34%), Positives = 17/32 (53%)
Query: 613 PCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
PC H G C++ F C C + + GP C ++
Sbjct: 422 PCEHAGKCINTLGSFECQCLQGYTGPRCEIDV 453
Score = 35.4 bits (80), Expect = 0.35
Identities = 18/66 (27%), Positives = 27/66 (40%), Gaps = 1/66 (1%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
C PC +G +C T + C C A ++G C + C PC +C + + C
Sbjct: 873 CVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCD 932
Query: 870 AEATFR 875
FR
Sbjct: 933 CLPGFR 938
Score = 33.9 bits (76), Expect = 1.0
Identities = 13/31 (41%), Positives = 17/31 (54%)
Query: 610 RPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
+P C HGG+C + +RC C H GP C
Sbjct: 185 KPGLCRHGGTCHNEVGSYRCVCRATHTGPNC 215
Score = 33.9 bits (76), Expect = 1.0
Identities = 14/31 (45%), Positives = 17/31 (54%), Gaps = 2/31 (6%)
Query: 814 DPCFNGGTCLVTWND--FHCTCPANFTGPTC 842
+PC+N GTC T + C CPA F G C
Sbjct: 1395 NPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1425
Score = 32.7 bits (73), Expect = 2.3
Identities = 15/48 (31%), Positives = 19/48 (39%), Gaps = 7/48 (14%)
Query: 593 EDLGENVLLGCERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
ED EN+ + C C HG +C D F C+C G C
Sbjct: 330 EDCSENI-------DDCASAACFHGATCHDRVASFYCECPHGRTGLLC 370
Score = 31.6 bits (70), Expect = 5.1
Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 5/55 (9%)
Query: 591 LPEDLGENVLLGCERR-EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
LP G+N CE + C C +GG+CVD + C C G C +++
Sbjct: 246 LPGFTGQN----CEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDV 296
Score = 31.6 bits (70), Expect = 5.1
Identities = 13/33 (39%), Positives = 17/33 (51%), Gaps = 1/33 (3%)
Query: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
+C PCVHG +C D ++CDC G C
Sbjct: 719 ECNSNPCVHG-ACRDSLNGYKCDCDPGWSGTNC 750
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 343 bits (881), Expect = 5e-94
Identities = 167/434 (38%), Positives = 229/434 (52%), Gaps = 44/434 (10%)
Query: 42 CASDPCAPGTECQATESGGYTCGPMEP----------RGCATQPCHHGALCVPQGPDPTG 91
CAS+PC C + GYTC + P C+ PC + A+C + P+
Sbjct: 799 CASNPCLNQGTC-FDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVC-KESPNFES 856
Query: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
+ C C PG+QG RC +DIDEC S+PC + C N Y C CP G++G+ CE ++D+C
Sbjct: 857 YTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCL 916
Query: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA 211
+ PC +GGSC+DGV +F C+C PG+ G +CQ D++EC S+PC +GGTC D VN + C C
Sbjct: 917 ANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQ 976
Query: 212 GTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQ 271
G++G HCE + EC + C + +C++G+ SF CLC G++G C + +EC+S PC
Sbjct: 977 -AGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCL 1035
Query: 272 HGGRCL------QRSDPALYGGVQAAFPGAFSFR-----------HAAGFLCHCPPGFEG 314
+ G C+ + S P Y G R A C CP G+ G
Sbjct: 1036 NEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAG 1095
Query: 315 ADC---GVEVDECASRP-------CLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLS 364
A C V D ASR C + G C + N C CP GY G CEE +DEC S
Sbjct: 1096 AYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECAS 1155
Query: 365 DPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVC 424
+PC HG TCSD + GY C C + G +C ++ CQ C TCI + V+ + C
Sbjct: 1156 NPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDL----VNHFKC 1211
Query: 425 HCPPGTHGPFCGQN 438
CPPGT G C +N
Sbjct: 1212 SCPPGTRGLLCEEN 1225
Score = 329 bits (843), Expect = 1e-89
Identities = 168/433 (38%), Positives = 224/433 (51%), Gaps = 50/433 (11%)
Query: 41 ACASDPCAPGTECQATE-SGGYTCG-PMEPRG---------CA---TQPCHHGALCVPQG 86
AC S+PC G C +G Y C P +G CA + PC H CV
Sbjct: 378 ACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTD 437
Query: 87 PDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME 146
F C C+ G+ GPRCE+DI+EC S PC + ATC + + C C G+ GV CE+E
Sbjct: 438 G---AFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELE 494
Query: 147 VDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF 206
++EC S PC++ G C+D V F+C+C PG+ G CQ+D+D+C S PC +G C D NG+
Sbjct: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGY 554
Query: 207 RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECA 266
C CA TG+ G CE + C PC H+ C +G+ S+ C+C PGY G +C DEC
Sbjct: 555 ECQCA-TGFTGVLCEENIDNCDPDPC-HHGQCQDGIDSYTCICNPGYMGAICSDQIDECY 612
Query: 267 SSPCQHGGRCLQRSDPALYGGVQA-AFPGA------FSFRHAAG--------------FL 305
SSPC + GRC+ L G Q PG +F A +
Sbjct: 613 SSPCLNDGRCID-----LVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYS 667
Query: 306 CHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSD 365
C C PGF G C +++DECAS PC G C + NGF+C CP+G P+C V+ECLS+
Sbjct: 668 CVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSN 727
Query: 366 PCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCH 425
PC+H G C+ ++GY C C W G +C V C + C TC ++ V+ Y C
Sbjct: 728 PCIH-GNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTC----DNLVNGYRCT 782
Query: 426 CPPGTHGPFCGQN 438
C G G C N
Sbjct: 783 CKKGFKGYNCQVN 795
Score = 324 bits (831), Expect = 3e-88
Identities = 158/414 (38%), Positives = 216/414 (52%), Gaps = 46/414 (11%)
Query: 36 SEPPSACASDPCAPGTECQATESGGYTCGPMEPRG-----------CATQPCHHGALCVP 84
SE CA C PG+ C ++C M P G C + PCH GALC
Sbjct: 336 SENIDDCAFASCTPGSTC-IDRVASFSC--MCPEGKAGLLCHLDDACISNPCHKGALC-D 391
Query: 85 QGPDPTGFRCYCVPGFQGPRCELDIDECA---SRPCHHGATCRNLADRYECHCPLGYAGV 141
P + C C G++G C D+DECA S PC H C N + C C GYAG
Sbjct: 392 TNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGP 451
Query: 142 TCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHD 201
CEM+++EC S PC + +CLD +G F C+C PG+ G C+L+++ECQS PC + G C D
Sbjct: 452 RCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVD 511
Query: 202 LVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVD 261
VN F+C C G+ G C+ ++ +C+S PC + A C++ + C C G++G LCE +
Sbjct: 512 KVNRFQCLCP-PGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEEN 570
Query: 262 EDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEV 321
D C PC H G+C D + C C PG+ GA C ++
Sbjct: 571 IDNCDPDPCHH-GQCQDGID---------------------SYTCICNPGYMGAICSDQI 608
Query: 322 DECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYI 381
DEC S PCLN G C DL NG+QC+C G +G CE + D+C S+PC+H G C D + Y
Sbjct: 609 DECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIH-GICMDGINRYS 667
Query: 382 CRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
C C + G+ C++ + C + C ATCI +GV+ + C CP G H P C
Sbjct: 668 CVCSPGFTGQRCNIDIDECASNPCRKGATCI----NGVNGFRCICPEGPHHPSC 717
Score = 311 bits (797), Expect = 3e-84
Identities = 151/444 (34%), Positives = 215/444 (48%), Gaps = 81/444 (18%)
Query: 42 CASDPCAPGTECQATESGGYTC----GPMEP------RGCATQPCHHGALCVPQGPDPTG 91
CAS+PC G C G+ C GP P C + PC HG +G
Sbjct: 686 CASNPCRKGATC-INGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCT----GGLSG 740
Query: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
++C C G+ G CE+D +EC S PC +G TC NL + Y C C G+ G C++ +DECA
Sbjct: 741 YKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECA 800
Query: 152 SAPCLHGGSCLDGVG----------------------------------------SFRCV 171
S PCL+ G+C D + S+ C+
Sbjct: 801 SNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCL 860
Query: 172 CAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAP 231
CAPG+ G RC +D+DEC S+PC + G CH+ + C+C G+ G CE ++ +C + P
Sbjct: 861 CAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECP-PGFSGMDCEEDIDDCLANP 919
Query: 232 CEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAA 291
C++ SC++G+ +F CLC PG++G+ C+ D +EC S PC++GG C SD
Sbjct: 920 CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTC---SD---------- 966
Query: 292 FPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYA 351
+ + C C GF+G C ++EC C NGG C D N F C CP G+
Sbjct: 967 --------YVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFT 1018
Query: 352 GPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATC 411
G C +++EC S PCL+ GTC D + Y C CP + G++C + C C TC
Sbjct: 1019 GSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTC 1078
Query: 412 IPIFESGVHSYVCHCPPGTHGPFC 435
+ + S C CP G G +C
Sbjct: 1079 V---QKKAESQ-CLCPSGWAGAYC 1098
Score = 297 bits (761), Expect = 4e-80
Identities = 156/461 (33%), Positives = 211/461 (45%), Gaps = 86/461 (18%)
Query: 42 CASDPCAPGTECQATESGGYTCGPMEP----------RGCATQPCHHGALCVPQGPDPTG 91
CA PC G C+ T + C + C C +G +CV
Sbjct: 225 CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVD---GVNT 281
Query: 92 FRCYCVPGFQGPRCELDIDECASRP--CHHGATCRNLADRYECHCPLGYAGVTCEMEVDE 149
+ C C P + G C D+DEC +P C +G TC N Y C C G++G C +D+
Sbjct: 282 YNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDD 341
Query: 150 CASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLD------------------------- 184
CA A C G +C+D V SF C+C G G C LD
Sbjct: 342 CAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYIC 401
Query: 185 --------------LDEC---QSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLEC 227
+DEC S PC H G C + F C+C GY G CE ++ EC
Sbjct: 402 TCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECL-KGYAGPRCEMDINEC 460
Query: 228 ASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGG 287
S PC+++A+CL+ +G F CLC PG+ G CE++ +EC S+PC + G+C+ + +
Sbjct: 461 HSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNR----- 515
Query: 288 VQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCP 347
F C CPPGF G C +++D+C+S PCLNG C D PNG++C C
Sbjct: 516 ----------------FQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCA 559
Query: 348 DGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPL 407
G+ G CEE++D C DPC H G C D + Y C C + G CS Q+ C C
Sbjct: 560 TGFTGVLCEENIDNCDPDPC-HHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLN 618
Query: 408 AATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSVMAGSP 448
CI + V+ Y C+C PGT G C N F A +P
Sbjct: 619 DGRCIDL----VNGYQCNCQPGTSGVNCEIN--FDDCASNP 653
Score = 293 bits (749), Expect = 9e-79
Identities = 150/412 (36%), Positives = 208/412 (50%), Gaps = 46/412 (11%)
Query: 41 ACASDPCAPGTECQATESGGYTCGPM---EPRGCATQ--------PCHHGALCVPQGPDP 89
AC S PCA G+ C T + ++C + + C T C HG C+ P
Sbjct: 147 ACLSHPCANGSTC-TTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNL---P 202
Query: 90 TGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLAD-RYECHCPLGYAGVTCEMEVD 148
++C C GF G C+ CA PC +G TCR D +EC+C G+ G TCE +D
Sbjct: 203 GSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNID 262
Query: 149 ECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQP--CAHGGTCHDLVNGF 206
+C + C +GG C+DGV ++ C C P + G C D+DEC QP C +GGTC + G+
Sbjct: 263 DCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGY 322
Query: 207 RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECA 266
C C G+ G C + +CA A C ++C++ + SF C+C G +G LC +D D C
Sbjct: 323 GCVCV-NGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLD-DACI 380
Query: 267 SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECA- 325
S+PC G C D G ++C CP G++GADC +VDECA
Sbjct: 381 SNPCHKGALC----DTNPLNG---------------QYICTCPQGYKGADCTEDVDECAM 421
Query: 326 --SRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICR 383
S PC + G C + F C C GYAGP CE D++EC SDPC + TC D + G+ C
Sbjct: 422 ANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCL 481
Query: 384 CPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
C + G C +++ CQ + C C+ V+ + C CPPG GP C
Sbjct: 482 CMPGFKGVHCELEINECQSNPCVNNGQCV----DKVNRFQCLCPPGFTGPVC 529
Score = 286 bits (733), Expect = 7e-77
Identities = 154/476 (32%), Positives = 214/476 (44%), Gaps = 85/476 (17%)
Query: 42 CASDPCAPGTECQ-ATESGGYTCGP--------MEPRGCATQPCHHGALCVPQGPDPTGF 92
C ++PC G C + C P + C ++PC +G C +
Sbjct: 915 CLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDY---VNSY 971
Query: 93 RCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECAS 152
C C GF G CE +I+EC C +G TC + + + C CP+G+ G C E++EC+S
Sbjct: 972 TCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSS 1031
Query: 153 APCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDL---------- 202
PCL+ G+C+DG+G++RC C GY G CQ ++ C PC + GTC
Sbjct: 1032 HPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPS 1091
Query: 203 --------VNGFRCDCAGT-----------------------------GYEGTHCEREVL 225
V CD A + GY G++CE ++
Sbjct: 1092 GWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLD 1151
Query: 226 ECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALY 285
ECAS PC+H A+C + +G +RC C PGY G CE + DEC + PCQ+GG C+ +
Sbjct: 1152 ECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNH--- 1208
Query: 286 GGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRP-CLNGGHCQDLPNGFQC 344
F C CPPG G C +D+CA P CLNGG C D G+ C
Sbjct: 1209 ------------------FKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSC 1250
Query: 345 HCPDGYAGPTCEEDVDECLSDPCLHGGT--CSDTVAGYICRCPETWGGRDCSVQLTGCQG 402
C G+AG CE D++ECLS+PC G+ C Y+C C + GR C + C
Sbjct: 1251 RCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQ 1310
Query: 403 HTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSVMAGSPIQASVPAGGP 458
C TC + + ++C CPPG G C Q++ V Q A GP
Sbjct: 1311 MPCLNGGTC-AVASNMPDGFICRCPPGFSGARC-QSSCGQVKCRKGEQCVHTASGP 1364
Score = 253 bits (646), Expect = 8e-67
Identities = 137/370 (37%), Positives = 183/370 (49%), Gaps = 37/370 (10%)
Query: 74 QPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATC--RNLADRYE 131
+PC + +CV + TG+ C C GF G C+ D C C +G TC + + +
Sbjct: 33 EPCVNEGMCVTYH-NGTGY-CKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKAT 89
Query: 132 CHCPLGYAGVTCEMEVDE--CASAPCLHGGSC-LDGVGSFRCVCAPGYGGTRCQLDLDEC 188
C C G+ G C+ S PCL+GG+C + ++ C C G+ G CQ D C
Sbjct: 90 CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DAC 148
Query: 189 QSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLEC-ASAPCEHNASCLEGLGSFRC 247
S PCA+G TC + N F C C TG+ G CE +V EC C+H +CL GS++C
Sbjct: 149 LSHPCANGSTCTTVANQFSCKCL-TGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQC 207
Query: 248 LCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCH 307
C G++G+ C+ CA SPC +GG C Q D F+F C+
Sbjct: 208 QCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGD--------------FTFE------CN 247
Query: 308 CPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDP- 366
C PGFEG+ C +D+C + C NGG C D N + C CP + G C EDVDECL P
Sbjct: 248 CLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPN 307
Query: 367 -CLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCH 425
C +GGTC++ GY C C W G DCS + C +C +TCI V S+ C
Sbjct: 308 ACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCI----DRVASFSCM 363
Query: 426 CPPGTHGPFC 435
CP G G C
Sbjct: 364 CPEGKAGLLC 373
Score = 238 bits (606), Expect = 4e-62
Identities = 119/325 (36%), Positives = 156/325 (48%), Gaps = 36/325 (11%)
Query: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCP 135
C H +C+ G C C G+ G CE +DECAS PC HGATC + Y C C
Sbjct: 1120 CQHSGVCINAG---NTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECV 1176
Query: 136 LGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQP-CA 194
GY GV CE EVDEC + PC +GG+C+D V F+C C PG G C+ ++D+C P C
Sbjct: 1177 PGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCL 1236
Query: 195 HGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPC--EHNASCLEGLGSFRCLCWPG 252
+GG C D + G+ C C G+ G CE ++ EC S PC E + C++ + C+C
Sbjct: 1237 NGGQCMDRIGGYSCRCL-PGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSA 1295
Query: 253 YSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGF 312
++G CE D C PC +GG C A + GF+C CPPGF
Sbjct: 1296 FTGRHCETFVDVCPQMPCLNGGTC------------------AVASNMPDGFICRCPPGF 1337
Query: 313 EGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGT 372
GA C C C G C +G +C CP + CE C S PC HGG+
Sbjct: 1338 SGARC---QSSCGQVKCRKGEQCVHTASGPRCFCP---SPRDCESG---CASSPCQHGGS 1388
Query: 373 C--SDTVAGYICRCPETWGGRDCSV 395
C Y C+C + G C +
Sbjct: 1389 CHPQRQPPYYSCQCAPPFSGSRCEL 1413
Score = 204 bits (518), Expect = 6e-52
Identities = 122/384 (31%), Positives = 168/384 (43%), Gaps = 85/384 (22%)
Query: 32 GTVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTG 91
G+ E CAS+PC G C + GGY C CVP
Sbjct: 1143 GSYCEEQLDECASNPCQHGATC-SDFIGGYRCE-----------------CVP------- 1177
Query: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
G+QG CE ++DEC ++PC +G TC +L + ++C CP G G+ CE +D+CA
Sbjct: 1178 -------GYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCA 1230
Query: 152 SAP-CLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGT--CHDLVNGFRC 208
P CL+GG C+D +G + C C PG+ G RC+ D++EC S PC+ G+ C L N + C
Sbjct: 1231 RGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLC 1290
Query: 209 DCAGTGYEGTHCEREVLECASAPCEHNASCLEGLG---SFRCLCWPGYSGELCEVDEDEC 265
C + + G HCE V C PC + +C F C C PG+SG C + C
Sbjct: 1291 VCR-SAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARC---QSSC 1346
Query: 266 ASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECA 325
C+ G +C+ A+G C CP DC CA
Sbjct: 1347 GQVKCRKGEQCVHT---------------------ASGPRCFCP---SPRDC---ESGCA 1379
Query: 326 SRPCLNGGHC--QDLPNGFQCHCPDGYAGPTCE-------EDVDECLSDPC---LHGGTC 373
S PC +GG C Q P + C C ++G CE CLS C G C
Sbjct: 1380 SSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVC 1439
Query: 374 SDTVAGYICRCPETWGGRDCSVQL 397
+ + C+ W G DCS+ +
Sbjct: 1440 DEACNSHACQ----WDGGDCSLTM 1459
Score = 155 bits (391), Expect = 3e-37
Identities = 89/293 (30%), Positives = 130/293 (44%), Gaps = 36/293 (12%)
Query: 154 PCLHGGSCLD-GVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTC--HDLVNGFRCDC 210
PC++ G C+ G+ C C G+ G CQ D C+ C +GGTC ++ C C
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKATCRC 92
Query: 211 AGTGYEGTHCEREVLE--CASAPCEHNASC-LEGLGSFRCLCWPGYSGELCEVDEDECAS 267
A +G+ G C+ S PC + +C + ++ C C G++G+ C+ D C S
Sbjct: 93 A-SGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLS 150
Query: 268 SPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDEC-AS 326
PC +G C ++ F C C GF G C +V+EC
Sbjct: 151 HPCANGSTCTTVANQ---------------------FSCKCLTGFTGQKCETDVNECDIP 189
Query: 327 RPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVA-GYICRCP 385
C +GG C +LP +QC CP G+ G C+ C PC++GGTC T + C C
Sbjct: 190 GHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCL 249
Query: 386 ETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438
+ G C + C H C C+ GV++Y C CPP G FC ++
Sbjct: 250 PGFEGSTCERNIDDCPNHRCQNGGVCV----DGVNTYNCRCPPQWTGQFCTED 298
Score = 126 bits (316), Expect = 2e-28
Identities = 59/153 (38%), Positives = 77/153 (50%), Gaps = 7/153 (4%)
Query: 1060 CAPSPCLHDGACRDL--FDAFACACGPGWEGPRCEAHVDPCHSAPCA-RGRCHTHPDGRF 1116
C+P+PC + C++ F+++ C C PGW+G RC +D C S PC G CH + G +
Sbjct: 837 CSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCH-NTQGSY 895
Query: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP 1176
C CPPGF G C + +C N C +G C G +C CL G G +CQ
Sbjct: 896 MCECPPGFSGMDCEEDI--DDCLAN-PCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNE 952
Query: 1177 CEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
C + PC NGGTC C C A F G CE
Sbjct: 953 CLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCE 985
Score = 115 bits (287), Expect = 4e-25
Identities = 65/164 (39%), Positives = 82/164 (50%), Gaps = 13/164 (7%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDG--RFE 1117
C SPCL+DG C DL + + C C PG G CE + D C S PC G C DG R+
Sbjct: 611 CYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGIC---MDGINRYS 667
Query: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
C C PGF G RC + + EC+ N C G+ C G C C EG C C
Sbjct: 668 CVCSPGFTGQRCNIDI--DECASN-PCRKGATCINGVNGFRCICPEGPHHPSCYSQVNEC 724
Query: 1178 EANPCLNGGTCRAAGGVS--ECICNARFSGQFCEVAKGLPLPLP 1219
+NPC++G GG+S +C+C+A + G CEV K L P
Sbjct: 725 LSNPCIHG---NCTGGLSGYKCLCDAGWVGINCEVDKNECLSNP 765
Score = 114 bits (286), Expect = 5e-25
Identities = 53/152 (34%), Positives = 73/152 (48%), Gaps = 4/152 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
CA +PC H C D + C C PG++G CE VD C + PC G F+C
Sbjct: 1153 CASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCS 1212
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
CPPG G C + +C+ CL+G C +C CL G AG+RC+ C +
Sbjct: 1213 CPPGTRGLLCEENI--DDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLS 1270
Query: 1180 NPCLNGGT--CRAAGGVSECICNARFSGQFCE 1209
NPC + G+ C C+C + F+G+ CE
Sbjct: 1271 NPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCE 1302
Score = 111 bits (277), Expect = 5e-24
Identities = 58/154 (37%), Positives = 72/154 (46%), Gaps = 5/154 (3%)
Query: 1058 PVCAPSPCLHDGACRDLF-DAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRF 1116
P PCL+ G C L D + C C G+ G C+ D C S PCA G T +F
Sbjct: 108 PCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ-WTDACLSHPCANGSTCTTVANQF 166
Query: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP 1176
C+C GF G +C V EC + C G C + C C +G GQ C +P
Sbjct: 167 SCKCLTGFTGQKCETDV--NECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVP 224
Query: 1177 CEANPCLNGGTCRAAGGVS-ECICNARFSGQFCE 1209
C +PC+NGGTCR G + EC C F G CE
Sbjct: 225 CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCE 258
Score = 110 bits (274), Expect = 1e-23
Identities = 55/147 (37%), Positives = 66/147 (44%), Gaps = 3/147 (2%)
Query: 1063 SPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPP 1122
+PC H G C + AF C C G+ GPRCE ++ CHS PC G F C C P
Sbjct: 425 NPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMP 484
Query: 1123 GFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPC 1182
GF G C L + EC N C++ C C C G G CQ+ C + PC
Sbjct: 485 GFKGVHCELEI--NECQSN-PCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPC 541
Query: 1183 LNGGTCRAAGGVSECICNARFSGQFCE 1209
LNG C EC C F+G CE
Sbjct: 542 LNGAKCIDHPNGYECQCATGFTGVLCE 568
Score = 109 bits (272), Expect = 2e-23
Identities = 51/149 (34%), Positives = 70/149 (46%), Gaps = 4/149 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C PC +D C D F C C PG++G CE ++ C S PC RF+C
Sbjct: 460 CHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
CPPGF GP C++ + +CS + CL+G+ C C C G G C+ C+
Sbjct: 520 CPPGFTGPVCQIDI--DDCS-STPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP 576
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFC 1208
+PC + G C+ CICN + G C
Sbjct: 577 DPC-HHGQCQDGIDSYTCICNPGYMGAIC 604
Score = 107 bits (266), Expect = 1e-22
Identities = 50/151 (33%), Positives = 72/151 (47%), Gaps = 3/151 (1%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C PC + G C D +++ C C G++G CE +++ C + C G F C
Sbjct: 953 CLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCL 1012
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
CP GF G C + ECS + CL+ C G CSC G G+ CQ C
Sbjct: 1013 CPVGFTGSFCLHEI--NECSSH-PCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSR 1069
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
+PC N GTC S+C+C + ++G +C+V
Sbjct: 1070 SPCKNKGTCVQKKAESQCLCPSGWAGAYCDV 1100
Score = 106 bits (264), Expect = 2e-22
Identities = 53/141 (37%), Positives = 70/141 (49%), Gaps = 7/141 (4%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTHPDGRFEC 1118
C P PC H G C+D D++ C C PG+ G C +D C+S+PC GRC +G ++C
Sbjct: 574 CDPDPC-HHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNG-YQC 631
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
C PG G C + +C+ N C+ G C G +C C G GQRC + C
Sbjct: 632 NCQPGTSGVNCE--INFDDCASN-PCIHGI-CMDGINRYSCVCSPGFTGQRCNIDIDECA 687
Query: 1179 ANPCLNGGTCRAAGGVSECIC 1199
+NPC G TC CIC
Sbjct: 688 SNPCRKGATCINGVNGFRCIC 708
Score = 104 bits (260), Expect = 5e-22
Identities = 53/152 (34%), Positives = 74/152 (48%), Gaps = 6/152 (3%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
C +PC+++G C D + F C C PG+ GP C+ +D C S PC G +C HP+G +EC
Sbjct: 498 CQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNG-YEC 556
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
+C GF G C + + + C G C+ G + C C G G C C
Sbjct: 557 QCATGFTGVLCEENIDNCDPD---PCHHGQ-CQDGIDSYTCICNPGYMGAICSDQIDECY 612
Query: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
++PCLN G C +C C SG CE+
Sbjct: 613 SSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEI 644
Score = 104 bits (260), Expect = 5e-22
Identities = 49/155 (31%), Positives = 75/155 (48%), Gaps = 3/155 (1%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C +PC + G+C D + F+C C PG+ G +C+ ++ C S PC G + + C+
Sbjct: 915 CLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCK 974
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
C GF G C + EC+ + +C +G C G + +C C G G C C +
Sbjct: 975 CQAGFDGVHCENNI--NECTES-SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSS 1031
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGL 1214
+PCLN GTC G C C ++G+ C+ L
Sbjct: 1032 HPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNL 1066
Score = 100 bits (249), Expect = 9e-21
Identities = 57/167 (34%), Positives = 79/167 (47%), Gaps = 18/167 (10%)
Query: 1054 CRGAPVCAPSPCLHDGACRD---LFDAFACACGPGWEGPRCEAHVDPC---HSAPCAR-G 1106
C C +PC H GA D L + C C G++G C VD C +S PC G
Sbjct: 373 CHLDDACISNPC-HKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAG 431
Query: 1107 RCHTHPDGRFECRCPPGFGGPRCRLPVP---SKECSLNVTCLDGSPCEGGSPAANCSCLE 1163
+C + DG F C C G+ GPRC + + S C + TCLD GG C C+
Sbjct: 432 KC-VNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKI---GGF---TCLCMP 484
Query: 1164 GLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
G G C++ C++NPC+N G C +C+C F+G C++
Sbjct: 485 GFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
Score = 97.8 bits (242), Expect = 6e-20
Identities = 52/153 (33%), Positives = 71/153 (46%), Gaps = 3/153 (1%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR-CHTHP-DGRFE 1117
CA + C C D +F+C C G G C D C S PC +G C T+P +G++
Sbjct: 342 CAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYI 400
Query: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
C CP G+ G C V + + C C A +C CL+G AG RC++ C
Sbjct: 401 CTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINEC 460
Query: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
++PC N TC G C+C F G CE+
Sbjct: 461 HSDPCQNDATCLDKIGGFTCLCMPGFKGVHCEL 493
Score = 95.5 bits (236), Expect = 3e-19
Identities = 51/153 (33%), Positives = 66/153 (43%), Gaps = 4/153 (2%)
Query: 1060 CAPSPCLHDGACRDLFD-AFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFEC 1118
CAPSPC++ G CR D F C C PG+EG CE ++D C + C G + C
Sbjct: 225 CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNC 284
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNV-TCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
RCPP + G C V EC L C +G C + C C+ G +G C C
Sbjct: 285 RCPPQWTGQFCTEDV--DECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDC 342
Query: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
C G TC C+C +G C +
Sbjct: 343 AFASCTPGSTCIDRVASFSCMCPEGKAGLLCHL 375
Score = 94.7 bits (234), Expect = 5e-19
Identities = 47/153 (30%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C +PC+H G C + C C GW G CE + C S PC G + + C
Sbjct: 724 CLSNPCIH-GNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCT 782
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
C GF G C++ + EC+ N CL+ C C C+ G+ CQ PC
Sbjct: 783 CKKGFKGYNCQVNI--DECASN-PCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSP 839
Query: 1180 NPCLNGGTCRAAGGVSE--CICNARFSGQFCEV 1210
NPC N C+ + C+C + GQ C +
Sbjct: 840 NPCENAAVCKESPNFESYTCLCAPGWQGQRCTI 872
Score = 94.0 bits (232), Expect = 8e-19
Identities = 50/158 (31%), Positives = 73/158 (46%), Gaps = 7/158 (4%)
Query: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCH-SAPCARGRCHTHP 1112
C+ C PC + C + + F+C C G+ G +CE V+ C C G +
Sbjct: 142 CQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNL 201
Query: 1113 DGRFECRCPPGFGGPRC-RLPVPSKECSLNVTCLDGSPC-EGGSPAANCSCLEGLAGQRC 1170
G ++C+CP GF G C L VP C+ + C++G C + G C+CL G G C
Sbjct: 202 PGSYQCQCPQGFTGQYCDSLYVP---CAPS-PCVNGGTCRQTGDFTFECNCLPGFEGSTC 257
Query: 1171 QVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
+ C + C NGG C C C +++GQFC
Sbjct: 258 ERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFC 295
Score = 93.2 bits (230), Expect = 1e-18
Identities = 49/159 (30%), Positives = 68/159 (42%), Gaps = 19/159 (11%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCA-RGRCHTHPDGRFEC 1118
C +PC + G C +L + + C C G++G C+ ++D C S PC +G C G + C
Sbjct: 761 CLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISG-YTC 819
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGS--------PAANCSCLEGLAGQRC 1170
C LP K C + +PCE + + C C G GQRC
Sbjct: 820 HCV---------LPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRC 870
Query: 1171 QVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
+ C + PC+N G C G C C FSG CE
Sbjct: 871 TIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE 909
Score = 92.0 bits (227), Expect = 3e-18
Identities = 88/313 (28%), Positives = 111/313 (35%), Gaps = 72/313 (23%)
Query: 42 CASDPCAPGTECQATE-SGGYTC---GPMEPRGCAT-------QPCHHGALCVPQGPDPT 90
C S+PC+ + + Y C R C T PC +G C P
Sbjct: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPD 1327
Query: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC 150
GF C C PGF G RC+ C C G C + A C CP + CE C
Sbjct: 1328 GFICRCPPGFSGARCQ---SSCGQVKCRKGEQCVHTASGPRCFCP---SPRDCE---SGC 1378
Query: 151 ASAPCLHGGSC--LDGVGSFRCVCAPGYGGTRCQL-------DLDECQSQPC---AHGGT 198
AS+PC HGGSC + C CAP + G+RC+L C SQ C A G
Sbjct: 1379 ASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGV 1438
Query: 199 CHDLVNGFRCDCAGTGYEGTHCEREVLECAS-APCEH--NASCLEGLGSFRCLCWPGYSG 255
C + N C G G E C+S PC N C E + CL
Sbjct: 1439 CDEACNSHACQWDG-GDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECL------- 1490
Query: 256 ELCEVDEDECA--SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFE 313
D EC S C++ C A F+ HC G
Sbjct: 1491 ----FDNFECQGNSKTCKYDKYC------------------ADHFKDN-----HCDQGCN 1523
Query: 314 GADCGVEVDECAS 326
+CG + +CA+
Sbjct: 1524 SEECGWDGLDCAA 1536
Score = 90.9 bits (224), Expect = 7e-18
Identities = 51/146 (34%), Positives = 62/146 (42%), Gaps = 4/146 (2%)
Query: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
C H G C + + C C G+ G CE +D C S PC G + G + C C PG+
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179
Query: 1125 GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANP-CL 1183
G C V EC N C +G C CSC G G C+ C P CL
Sbjct: 1180 QGVNCEYEV--DECQ-NQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCL 1236
Query: 1184 NGGTCRAAGGVSECICNARFSGQFCE 1209
NGG C G C C F+G+ CE
Sbjct: 1237 NGGQCMDRIGGYSCRCLPGFAGERCE 1262
Score = 88.6 bits (218), Expect = 4e-17
Identities = 45/159 (28%), Positives = 63/159 (39%), Gaps = 11/159 (6%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C+ PCL++G C D + C+C G+ G C+ V+ C +PC +C
Sbjct: 1029 CSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCL 1088
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVT---------CLDGSPCEGGSPAANCSCLEGLAGQRC 1170
CP G+ G C VP+ C + + C C C C G G C
Sbjct: 1089 CPSGWAGAYC--DVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYC 1146
Query: 1171 QVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
+ C +NPC +G TC G C C + G CE
Sbjct: 1147 EEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCE 1185
Score = 83.6 bits (205), Expect = 1e-15
Identities = 54/168 (32%), Positives = 71/168 (42%), Gaps = 21/168 (12%)
Query: 1060 CAPSPCLHDGA--CRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR----CHTHPD 1113
C +PC +G+ C L + + C C + G CE VD C PC G PD
Sbjct: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPD 1327
Query: 1114 GRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVP 1173
G F CRCPPGF G RC+ C V C G C + C C + + C+
Sbjct: 1328 G-FICRCPPGFSGARCQ-----SSCG-QVKCRKGEQCVHTASGPRCFC---PSPRDCE-- 1375
Query: 1174 TLPCEANPCLNGGTC--RAAGGVSECICNARFSGQFCEVAKGLPLPLP 1219
C ++PC +GG+C + C C FSG CE+ P P
Sbjct: 1376 -SGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPP 1422
Score = 79.3 bits (194), Expect = 2e-14
Identities = 47/161 (29%), Positives = 60/161 (37%), Gaps = 13/161 (8%)
Query: 1059 VCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTH------- 1111
+C+ SPC + G C C C GW G C+ C A RG H
Sbjct: 1066 LCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGV 1125
Query: 1112 ---PDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQ 1168
C+CP G+ G C + EC+ N C G+ C C C+ G G
Sbjct: 1126 CINAGNTHYCQCPLGYTGSYCEEQL--DECASN-PCQHGATCSDFIGGYRCECVPGYQGV 1182
Query: 1169 RCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
C+ C+ PC NGGTC +C C G CE
Sbjct: 1183 NCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCE 1223
Score = 73.6 bits (179), Expect = 1e-12
Identities = 48/151 (31%), Positives = 63/151 (41%), Gaps = 14/151 (9%)
Query: 1064 PCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPG 1123
P L L + C P +C +PC + G C T+ +G C+CP G
Sbjct: 2 PALRPALLWALLALWLCCAAPA-HALQCRDGYEPCVN----EGMCVTYHNGTGYCKCPEG 56
Query: 1124 FGGPRC--RLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTL-PC-EA 1179
F G C R P C TC+ + A C C G G+ CQ T PC +
Sbjct: 57 FLGEYCQHRDPCEKNRCQNGGTCV----AQAMLGKATCRCASGFTGEDCQYSTSHPCFVS 112
Query: 1180 NPCLNGGTCR-AAGGVSECICNARFSGQFCE 1209
PCLNGGTC + EC C F+G+ C+
Sbjct: 113 RPCLNGGTCHMLSRDTYECTCQVGFTGKECQ 143
Score = 59.3 bits (142), Expect = 2e-08
Identities = 26/65 (40%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
C +PC N G C+ N F C CP FTGP C + C PCL A C + P+G+ C
Sbjct: 498 CQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQ 557
Query: 870 AEATF 874
F
Sbjct: 558 CATGF 562
Score = 58.9 bits (141), Expect = 3e-08
Identities = 30/80 (37%), Positives = 38/80 (47%), Gaps = 9/80 (11%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
C+ CFNGGTC+ N F C CP FTG C ++ C PCL TC DG
Sbjct: 991 CTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTC---VDGL--- 1044
Query: 870 AEATFREGPPAAFSGHNASS 889
T+R P ++G N +
Sbjct: 1045 --GTYRCSCPLGYTGKNCQT 1062
Score = 54.3 bits (129), Expect = 7e-07
Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D C +PC NGG+C+ N F C C FTG C + C +PC TC + + +
Sbjct: 913 DDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYT 972
Query: 868 CVAEATF 874
C +A F
Sbjct: 973 CKCQAGF 979
Score = 52.8 bits (125), Expect = 2e-06
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
V ++ C +PC NGGTC N + CTC F G C + C PCL TC +
Sbjct: 756 VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDIS 815
Query: 865 GFVC 868
G+ C
Sbjct: 816 GYTC 819
Score = 51.6 bits (122), Expect = 5e-06
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
Query: 810 MCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVC 868
M + +PC + G C+ T FHC C + GP C + C PC ATC + GF C
Sbjct: 421 MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC 480
Query: 869 VAEATFR 875
+ F+
Sbjct: 481 LCMPGFK 487
Score = 51.2 bits (121), Expect = 6e-06
Identities = 27/67 (40%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Query: 1159 CSCLEGLAGQRCQVPTLPCEANPCLNGGTC--RAAGGVSECICNARFSGQFCEVAKGLPL 1216
C C EG G+ CQ PCE N C NGGTC +A G + C C + F+G+ C+ + P
Sbjct: 51 CKCPEGFLGEYCQHRD-PCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPC 109
Query: 1217 PLPFPLL 1223
+ P L
Sbjct: 110 FVSRPCL 116
Score = 50.8 bits (120), Expect = 8e-06
Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Query: 815 PCFNGGTC-LVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVPDGFVC 868
PC NGGTC +++ + + CTC FTG C C PC +TC V + F C
Sbjct: 114 PCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC 168
Score = 50.8 bits (120), Expect = 8e-06
Identities = 30/85 (35%), Positives = 39/85 (45%), Gaps = 14/85 (16%)
Query: 811 CSPDPCFNGGT--CLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATC---EEVPD 864
C +PC + G+ C+ ND+ C C + FTG C + CP PCL TC +PD
Sbjct: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPD 1327
Query: 865 GFVCVAEATFREGPPAAFSGHNASS 889
GF+C P FSG S
Sbjct: 1328 GFICRC--------PPGFSGARCQS 1344
Score = 48.9 bits (115), Expect = 3e-05
Identities = 33/101 (32%), Positives = 45/101 (44%), Gaps = 14/101 (13%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
++ D C+ +PC +G C+ N + C C FTG C + C PC ATC +
Sbjct: 644 INFDDCASNPCIHG-ICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVN 702
Query: 865 GFVCVAEATFREGP--PAAFSGHN------ASSGRLLGGLS 897
GF C+ EGP P+ +S N G GGLS
Sbjct: 703 GFRCICP----EGPHHPSCYSQVNECLSNPCIHGNCTGGLS 739
Score = 48.5 bits (114), Expect = 4e-05
Identities = 54/214 (25%), Positives = 69/214 (32%), Gaps = 53/214 (24%)
Query: 35 PSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRC 94
P + S CAS P C HG C PQ P + C
Sbjct: 1371 PRDCESGCASSP-----------------------------CQHGGSCHPQ-RQPPYYSC 1400
Query: 95 YCVPGFQGPRCEL-------DIDECASRPCHHGA---TCRNLADRYECHCPLGYAGVTCE 144
C P F G RCEL C S+ C A C + + C G +T E
Sbjct: 1401 QCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTME 1460
Query: 145 MEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQ--SQPCAHGGTCHDL 202
C+S C D + + C C D ECQ S+ C + C D
Sbjct: 1461 NPWANCSSPL-----PCWDYINN---QCDELCNTVECLFDNFECQGNSKTCKYDKYCADH 1512
Query: 203 VNGFRCDCAGTGYEGTHCEREVLECASAPCEHNA 236
CD G C + L+CA+ E+ A
Sbjct: 1513 FKDNHCD---QGCNSEECGWDGLDCAADQPENLA 1543
Score = 47.8 bits (112), Expect = 7e-05
Identities = 24/67 (35%), Positives = 27/67 (40%), Gaps = 4/67 (5%)
Query: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC---AQQLWCPGQPCLPPATCEE 861
C D C PC NG TC N F C C FTG C + PG C TC
Sbjct: 142 CQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGH-CQHGGTCLN 200
Query: 862 VPDGFVC 868
+P + C
Sbjct: 201 LPGSYQC 207
Score = 47.4 bits (111), Expect = 9e-05
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Query: 816 CFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVC 868
C + G C+ N +C CP +TG C +QL C PC ATC + G+ C
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRC 1173
Score = 47.0 bits (110), Expect = 1e-04
Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
Query: 811 CSPDPCFNGGTCLVTWN-DFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVC 868
C+P PC NGGTC T + F C C F G TC + + CP C C + + + C
Sbjct: 225 CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNC 284
Score = 47.0 bits (110), Expect = 1e-04
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D CS PC NG C+ N + C C FTG C + + C PC C++ D +
Sbjct: 534 DDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPC-HHGQCQDGIDSYT 592
Query: 868 CV 869
C+
Sbjct: 593 CI 594
Score = 47.0 bits (110), Expect = 1e-04
Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLW-CPGQPCLPPATCEEVP- 863
V+ D C+ +PC N GTC + + C C +TG C L C PC A C+E P
Sbjct: 794 VNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPN 853
Query: 864 -DGFVCV 869
+ + C+
Sbjct: 854 FESYTCL 860
Score = 46.6 bits (109), Expect = 2e-04
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL--WCPGQPCLPPATCEEVPDGF 866
D C PC NGGTC+ N F C+CP G C + + G CL C + G+
Sbjct: 1189 DECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGY 1248
Query: 867 VC 868
C
Sbjct: 1249 SC 1250
Score = 46.2 bits (108), Expect = 2e-04
Identities = 27/101 (26%), Positives = 40/101 (39%), Gaps = 9/101 (8%)
Query: 778 PFFPLPLDNSSQPSELGGRQS--------WNLTAGCVSEDMCSPDPCFNGGTCLVTWNDF 829
P P P +N++ E +S W + D C PC N G C T +
Sbjct: 836 PCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSY 895
Query: 830 HCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
C CP F+G C + + C PC +C + + F C+
Sbjct: 896 MCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCL 936
Score = 46.2 bits (108), Expect = 2e-04
Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 1/65 (1%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
C +PC NGGTC N + C C A F G C + C C TC + + F C+
Sbjct: 953 CLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCL 1012
Query: 870 AEATF 874
F
Sbjct: 1013 CPVGF 1017
Score = 45.8 bits (107), Expect = 3e-04
Identities = 27/86 (31%), Positives = 34/86 (39%), Gaps = 2/86 (2%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
C DPC N TCL F C C F G C ++ C PC+ C + + F C+
Sbjct: 460 CHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519
Query: 870 AEATFREGPPAAFSGHNASSGRLLGG 895
F GP + SS L G
Sbjct: 520 CPPGF-TGPVCQIDIDDCSSTPCLNG 544
Score = 45.4 bits (106), Expect = 3e-04
Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D C+ +PC G TC+ N F C CP P+C Q+ C PC+ C G+
Sbjct: 684 DECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI-HGNCTGGLSGYK 742
Query: 868 CVAEA 872
C+ +A
Sbjct: 743 CLCDA 747
Score = 45.4 bits (106), Expect = 3e-04
Identities = 18/45 (40%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Query: 601 LGCERR-EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
+ CE ++C+ PC +GG+C+DL HF+C C RG C + I
Sbjct: 1182 VNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENI 1226
Score = 44.7 bits (104), Expect = 6e-04
Identities = 20/53 (37%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 813 PDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPD 864
P C +GGTCL + C CP FTG C + + C PC+ TC + D
Sbjct: 189 PGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGD 241
Score = 44.7 bits (104), Expect = 6e-04
Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D C PDPC +G C + + C C + G C+ Q+ C PCL C ++ +G+
Sbjct: 572 DNCDPDPCHHG-QCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQ 630
Query: 868 C 868
C
Sbjct: 631 C 631
Score = 43.9 bits (102), Expect = 0.001
Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 1/61 (1%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D C+ +PC +G TC + C C + G C ++ C QPC TC ++ + F
Sbjct: 1151 DECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFK 1210
Query: 868 C 868
C
Sbjct: 1211 C 1211
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/63 (38%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 809 DMCSPDPCFNGGTCLVTWN---DFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVPDG 865
D+C PC NGGTC V N F C CP F+G C Q C C C G
Sbjct: 1306 DVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARC--QSSCGQVKCRKGEQCVHTASG 1363
Query: 866 FVC 868
C
Sbjct: 1364 PRC 1366
Score = 43.1 bits (100), Expect = 0.002
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQP--CLPPATCEEVPDG 865
D C C NGG C+ N ++C CP +TG C + + C QP C TC G
Sbjct: 262 DDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGG 321
Query: 866 FVCV 869
+ CV
Sbjct: 322 YGCV 325
Score = 42.4 bits (98), Expect = 0.003
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
V E + P+ C NGGTC + C C ++G C++ + C C P +TC +
Sbjct: 299 VDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVA 358
Query: 865 GFVCV 869
F C+
Sbjct: 359 SFSCM 363
Score = 42.0 bits (97), Expect = 0.004
Identities = 24/76 (31%), Positives = 31/76 (40%), Gaps = 6/76 (7%)
Query: 805 CVSEDMCSPDPCFNGGTCL--VTWNDFHCTCPANFTGPTCAQQLWCP---GQPCLPPATC 859
C D C + C NGGTC+ C C + FTG C P +PCL TC
Sbjct: 62 CQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTC 121
Query: 860 EEVP-DGFVCVAEATF 874
+ D + C + F
Sbjct: 122 HMLSRDTYECTCQVGF 137
Score = 39.7 bits (91), Expect = 0.019
Identities = 14/41 (34%), Positives = 23/41 (56%)
Query: 604 ERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
E+ ++C PC HG +C D +RC+C ++G C E+
Sbjct: 1148 EQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEV 1188
Score = 39.3 bits (90), Expect = 0.025
Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 4/70 (5%)
Query: 809 DMCSPDP-CFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPAT--CEEVPD 864
D C+ P C NGG C+ + C C F G C + C PC + C ++ +
Sbjct: 1227 DDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTN 1286
Query: 865 GFVCVAEATF 874
++CV + F
Sbjct: 1287 DYLCVCRSAF 1296
Score = 38.1 bits (87), Expect = 0.055
Identities = 15/37 (40%), Positives = 20/37 (54%)
Query: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
+C+ PCV+ G CVD F+C C GP C +I
Sbjct: 497 ECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDI 533
Score = 37.7 bits (86), Expect = 0.071
Identities = 19/67 (28%), Positives = 26/67 (38%), Gaps = 2/67 (2%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D C PC N G C+ N + C C +G C C PC+ C + + +
Sbjct: 609 DECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCI-HGICMDGINRYS 667
Query: 868 CVAEATF 874
CV F
Sbjct: 668 CVCSPGF 674
Score = 36.2 bits (82), Expect = 0.21
Identities = 68/314 (21%), Positives = 103/314 (32%), Gaps = 57/314 (18%)
Query: 346 CPDGYAGPTCEEDVDECLSDPCLHGGTCSD--TVAGYICRCPETWGGRDCSVQLTGCQGH 403
C DGY +PC++ G C GY C+CPE + G C + C+ +
Sbjct: 28 CRDGY--------------EPCVNEGMCVTYHNGTGY-CKCPEGFLGEYCQHR-DPCEKN 71
Query: 404 TCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSVMAGSPIQASVPAGGPLGLAL 463
C TC+ ++ + C C G F G++ +S + GG +
Sbjct: 72 RCQNGGTCVA--QAMLGKATCRCASG----FTGEDCQYSTSHPCFVSRPCLNGGTCHMLS 125
Query: 464 R--FRTTLPAGTLATRNDTKESLELALVA--ATLQATLWSYSTTVLVLRLPDLALND--- 516
R + T G ++ A +T +S L D
Sbjct: 126 RDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE 185
Query: 517 ----GHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALASTASATPLPAGISSAQLG 572
GH L+L +G + C + L + +P G + Q G
Sbjct: 186 CDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDS-----LYVPCAPSPCVNGGTCRQTG 240
Query: 573 DATF-AGCLQDVRVDGHLLLPEDLGENVLLGCERR-EQCRPLPCVHGGSCVDLWTHFRCD 630
D TF CL P G CER + C C +GG CVD + C
Sbjct: 241 DFTFECNCL-----------PGFEGST----CERNIDDCPNHRCQNGGVCVDGVNTYNCR 285
Query: 631 CARPHRGPTCADEI 644
C G C +++
Sbjct: 286 CPPQWTGQFCTEDV 299
Score = 36.2 bits (82), Expect = 0.21
Identities = 18/55 (32%), Positives = 21/55 (38%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVP 863
D C+ C G TC+ F C CP G C C PC A C+ P
Sbjct: 340 DDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNP 394
Score = 36.2 bits (82), Expect = 0.21
Identities = 13/32 (40%), Positives = 18/32 (56%)
Query: 613 PCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
PC H G CV+ F C+C + + GP C +I
Sbjct: 426 PCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI 457
Score = 36.2 bits (82), Expect = 0.21
Identities = 13/34 (38%), Positives = 19/34 (55%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC 842
++CS PC N GTC+ + C CP+ + G C
Sbjct: 1065 NLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC 1098
Score = 35.4 bits (80), Expect = 0.35
Identities = 14/41 (34%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Query: 601 LGCE-RREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
+ CE + +C PC +GG+C +L +RC C + +G C
Sbjct: 752 INCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNC 792
Score = 34.7 bits (78), Expect = 0.60
Identities = 16/47 (34%), Positives = 20/47 (42%), Gaps = 1/47 (2%)
Query: 814 DPCFNGGTCLVTWNDF-HCTCPANFTGPTCAQQLWCPGQPCLPPATC 859
+PC N G C+ N +C CP F G C + C C TC
Sbjct: 33 EPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTC 79
Score = 34.7 bits (78), Expect = 0.60
Identities = 12/38 (31%), Positives = 18/38 (47%)
Query: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
+ C PC++G C+D + C CA G C + I
Sbjct: 534 DDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI 571
Score = 34.3 bits (77), Expect = 0.79
Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 5/54 (9%)
Query: 808 EDMCSPDPCFNGGTCLVTWND--FHCTCPANFTGPTCAQQLWCPGQPCLPPATC 859
E C+ PC +GG+C + C C F+G C +L+ P PPATC
Sbjct: 1375 ESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRC--ELY-TAPPSTPPATC 1425
Score = 33.9 bits (76), Expect = 1.0
Identities = 11/34 (32%), Positives = 19/34 (55%)
Query: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
++C PC++ G+C D + + C C P+ G C
Sbjct: 797 DECASNPCLNQGTCFDDISGYTCHCVLPYTGKNC 830
Score = 33.9 bits (76), Expect = 1.0
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 5/71 (7%)
Query: 579 CLQDVRVDGHLLLPEDLGENVLLGCER-REQCRPLPCVHGGSCVDLWTHFRCDCARPHRG 637
C+ V L LP G+ C+ +C PC +GG+C D + C C G
Sbjct: 926 CMDGVNTFSCLCLPGFTGDK----CQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDG 981
Query: 638 PTCADEIPAAT 648
C + I T
Sbjct: 982 VHCENNINECT 992
Score = 33.5 bits (75), Expect = 1.3
Identities = 11/34 (32%), Positives = 19/34 (55%)
Query: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
++C PC++ G C+DL ++C+C G C
Sbjct: 609 DECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNC 642
Score = 33.1 bits (74), Expect = 1.8
Identities = 12/33 (36%), Positives = 18/33 (54%)
Query: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
+C PC++ G+CVD +RC C + G C
Sbjct: 1028 ECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNC 1060
Score = 33.1 bits (74), Expect = 1.8
Identities = 30/108 (27%), Positives = 37/108 (34%), Gaps = 11/108 (10%)
Query: 540 CPARLCVASGPVALASTAS---ATPLPAGISSAQLGDATFAGCLQDVRVDGHLLLPEDLG 596
CP C+ G A+AS P G S A+ + C Q G + G
Sbjct: 1308 CPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSS----CGQVKCRKGEQCVHTASG 1363
Query: 597 ENVLLGCER--REQCRPLPCVHGGSCVDLW--THFRCDCARPHRGPTC 640
R C PC HGGSC ++ C CA P G C
Sbjct: 1364 PRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRC 1411
Score = 32.3 bits (72), Expect = 3.0
Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 604 ERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
E + C P PC H G C D + C C + G C+D+I
Sbjct: 569 ENIDNCDPDPC-HHGQCQDGIDSYTCICNPGYMGAICSDQI 608
Score = 32.0 bits (71), Expect = 3.9
Identities = 16/43 (37%), Positives = 19/43 (44%), Gaps = 1/43 (2%)
Query: 603 CERR-EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
CE +C C +GG+CVD F C C G C EI
Sbjct: 984 CENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI 1026
Score = 31.6 bits (70), Expect = 5.1
Identities = 11/38 (28%), Positives = 19/38 (50%)
Query: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
++C PC G +C++ FRC C P+C ++
Sbjct: 684 DECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQV 721
Score = 31.6 bits (70), Expect = 5.1
Identities = 15/45 (33%), Positives = 21/45 (46%), Gaps = 1/45 (2%)
Query: 601 LGCERR-EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
+ CE + C PC +GGSC+D F C C G C ++
Sbjct: 906 MDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDM 950
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 336 bits (862), Expect = 7e-92
Identities = 201/618 (32%), Positives = 260/618 (42%), Gaps = 97/618 (15%)
Query: 41 ACASDPCAPGTECQATESGGY---TCGPMEPRGCATQ----------PCHHGALCV-PQG 86
AC S+PC C G TC P G Q PC H CV QG
Sbjct: 354 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQG 413
Query: 87 PDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME 146
F C C G+ GPRCE D++EC S PC + ATC + ++ C C G+ G CE++
Sbjct: 414 ----SFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVD 469
Query: 147 VDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF 206
+DEC S+PC++GG C D V F C C G+ G+ CQLD+DEC S PC +G C D +G+
Sbjct: 470 IDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGY 529
Query: 207 RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECA 266
C CA G+EGT C+R V +C+ PC H+ C++G+ SF C C PGY+G CE DEC
Sbjct: 530 ECRCA-EGFEGTLCDRNVDDCSPDPC-HHGRCVDGIASFSCACAPGYTGTRCESQVDECR 587
Query: 267 SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECAS 326
S PC+HGG+CL D +LC CP G G +C V +D+CAS
Sbjct: 588 SQPCRHGGKCLDLVDK---------------------YLCRCPSGTTGVNCEVNIDDCAS 626
Query: 327 RPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPE 386
PC G C+D N + C C G+ GP C +++EC S PC GG+C D G+ C CP
Sbjct: 627 NPC-TFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPP 685
Query: 387 TWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSVMAG 446
C C C I + C C PG GP C Q+
Sbjct: 686 GSLPPLCLPPSHPCAHEPCSHG-----ICYDAPGGFRCVCEPGWSGPRCSQSLARDACES 740
Query: 447 SPIQASVPAGGPLGLALRFRTTLPAGTLATRNDTKESLELALVAATLQATLWSYSTTVLV 506
P +A G + F T P G Q L S T
Sbjct: 741 QPCRA---GGTCSSDGMGFHCTCPPGVQGR-----------------QCELLSPCT---- 776
Query: 507 LRLPDLALNDGHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALASTASATPLPAGI 566
P+ + G L + + C + +GP T L
Sbjct: 777 ---PNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSF 833
Query: 567 SSAQLGDATFAGCLQDVRVDGHLLLPEDLGENVLLGCERREQCRPLPCVHGGSCVDLWTH 626
S G T C QD+ C P PC++GGSC D
Sbjct: 834 SCTCHGGYTGPSCDQDI-----------------------NDCDPNPCLNGGSCQDGVGS 870
Query: 627 FRCDCARPHRGPTCADEI 644
F C C GP CA ++
Sbjct: 871 FSCSCLPGFAGPRCARDV 888
Score = 323 bits (827), Expect = 8e-88
Identities = 175/476 (36%), Positives = 227/476 (47%), Gaps = 50/476 (10%)
Query: 41 ACASDPCAPGTECQATESGGYTCGPMEPRG--------CATQPCHHGALCVPQ-GPDPTG 91
AC S PC G C + G + P +G C PC HG C G P
Sbjct: 737 ACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPV- 795
Query: 92 FRCYCVPGFQGPRCELDIDECAS-RPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC 150
C C G+QGPRC+ D+DECA PC C NLA + C C GY G +C+ ++++C
Sbjct: 796 --CSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDC 853
Query: 151 ASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDC 210
PCL+GGSC DGVGSF C C PG+ G RC D+DEC S PC G TC D V F C C
Sbjct: 854 DPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVASFTCTC 912
Query: 211 AGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPC 270
GY G HCE+++ +C+ + C + +C++G+ SF CLC PGY+G C+ + D C S PC
Sbjct: 913 P-PGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPC 971
Query: 271 QHGGRCLQRSDPALYGGVQAAFPGA-------FSFRHAA---------GFLCHCPPGFEG 314
HGG C + P +F G + R G C CPPG+ G
Sbjct: 972 LHGGVC-SAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSG 1030
Query: 315 ADCGVEVDECASRP----------CLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLS 364
C + C C GG C D + C CP+G G CE++VD CL+
Sbjct: 1031 RLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLA 1090
Query: 365 DPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVC 424
PC HGGTC + GY+C C + G +C + C C +CI + V Y+C
Sbjct: 1091 QPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDL----VARYLC 1146
Query: 425 HCPPGTHGPFCGQNTTFSVMAGSPIQAS---VPAGGPLGLALRFRTTLPAGTLATR 477
CPPGT G C N G P+ + + G + L FR T P G R
Sbjct: 1147 SCPPGTLGVLCEINED-DCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLR 1201
Score = 311 bits (796), Expect = 3e-84
Identities = 159/460 (34%), Positives = 209/460 (45%), Gaps = 83/460 (18%)
Query: 32 GTVPSEPPSACASDPCAPGTECQATESGGYTCG----------PMEPRGCATQPCHHGAL 81
G + P CA PC G C+ + Y C + C C +G
Sbjct: 191 GPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGT 250
Query: 82 CVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRP--CHHGATCRNLADRYECHCPLGYA 139
CV + C C P + G C D+DEC +P CH+G TC N + C C G+
Sbjct: 251 CVD---GVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWT 307
Query: 140 GVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCA-------------------------- 173
G +C +D+CA+A C HG +C D V SF C C
Sbjct: 308 GESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICD 367
Query: 174 -------------PGYGGTRCQLDLDECQ--SQPCAHGGTCHDLVNGFRCDCAGTGYEGT 218
PG+ G C D+DEC + PC H G C + F C C G GY G
Sbjct: 368 TNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC-GRGYTGP 426
Query: 219 HCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQ 278
CE +V EC S PC + A+CL+ +G F C+C G++G CEVD DEC SSPC +GG C
Sbjct: 427 RCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKD 486
Query: 279 RSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDL 338
R + GF C CP GF G+ C ++VDECAS PC NG C D
Sbjct: 487 RVN---------------------GFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQ 525
Query: 339 PNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLT 398
P+G++C C +G+ G C+ +VD+C DPC H G C D +A + C C + G C Q+
Sbjct: 526 PDGYECRCAEGFEGTLCDRNVDDCSPDPC-HHGRCVDGIASFSCACAPGYTGTRCESQVD 584
Query: 399 GCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438
C+ C C+ + V Y+C CP GT G C N
Sbjct: 585 ECRSQPCRHGGKCLDL----VDKYLCRCPSGTTGVNCEVN 620
Score = 307 bits (787), Expect = 4e-83
Identities = 165/469 (35%), Positives = 216/469 (46%), Gaps = 81/469 (17%)
Query: 39 PSACASDPCAPGTECQATESGGYTCG---PMEPRGCAT--------QPCHHGALCVPQGP 87
P C S PCA G C G + C + R C + +PC HG C+
Sbjct: 120 PDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNT-- 177
Query: 88 DPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLAD-RYECHCPLGYAGVTCEME 146
P FRC C G+ GP CE CA PC +G TCR D Y+C C G+ G CE+
Sbjct: 178 -PGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVN 236
Query: 147 VDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQP--CAHGGTCHDLVN 204
VD+C CL+GG+C+DGV ++ C C P + G C D+DECQ QP C +GGTC + +
Sbjct: 237 VDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLG 296
Query: 205 GFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFR------------------ 246
G C C G+ G C + + +CA+A C H A+C + + SF
Sbjct: 297 GHSCVCV-NGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDAC 355
Query: 247 ---------------------CLCWPGYSGELCEVDEDECA--SSPCQHGGRCLQR---- 279
C C PG++G C+ D DEC+ ++PC+H GRC+
Sbjct: 356 VSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSF 415
Query: 280 --------SDPALYGGVQAAFPG-----AFSFRHAAGFLCHCPPGFEGADCGVEVDECAS 326
+ P V G A F C C GF G C V++DEC S
Sbjct: 416 LCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQS 475
Query: 327 RPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPE 386
PC+NGG C+D NGF C CP G++G TC+ DVDEC S PC +G C D GY CRC E
Sbjct: 476 SPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAE 535
Query: 387 TWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
+ G C + C C C+ G+ S+ C C PG G C
Sbjct: 536 GFEGTLCDRNVDDCSPDPCH-HGRCV----DGIASFSCACAPGYTGTRC 579
Score = 300 bits (768), Expect = 6e-81
Identities = 156/408 (38%), Positives = 197/408 (48%), Gaps = 49/408 (12%)
Query: 42 CASDPCAPGTECQATESGGYTC----GPMEP------RGCATQPCHHGALCVPQGPDPTG 91
CAS PC G C E+G + C G + P CA +PC HG +C P G
Sbjct: 661 CASSPCGEGGSCVDGENG-FRCLCPPGSLPPLCLPPSHPCAHEPCSHG-ICYDA---PGG 715
Query: 92 FRCYCVPGFQGPRCELDI--DECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDE 149
FRC C PG+ GPRC + D C S+PC G TC + + C CP G G CE+ +
Sbjct: 716 FRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL-LSP 774
Query: 150 CASAPCLHGGSCLDGVGSFR-CVCAPGYGGTRCQLDLDECQSQ-PCAHGGTCHDLVNGFR 207
C PC HGG C G C C G+ G RCQ D+DEC PC G C +L F
Sbjct: 775 CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFS 834
Query: 208 CDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECAS 267
C C G GY G C++++ +C PC + SC +G+GSF C C PG++G C D DEC S
Sbjct: 835 CTCHG-GYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLS 893
Query: 268 SPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASR 327
+PC G C H A F C CPPG+ G C ++ +C+
Sbjct: 894 NPCGPG-TCTD---------------------HVASFTCTCPPGYGGFHCEQDLPDCSPS 931
Query: 328 PCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPET 387
C NGG C D N F C C GY G C+ + D CLS PCLHGG CS G+ C C E+
Sbjct: 932 SCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLES 991
Query: 388 WGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
+ G C + C C C+ ++G + C CPPG G C
Sbjct: 992 FTGPQCQTLVDWCSRQPCQNGGRCV---QTGAY---CLCPPGWSGRLC 1033
Score = 299 bits (766), Expect = 1e-80
Identities = 173/474 (36%), Positives = 226/474 (47%), Gaps = 63/474 (13%)
Query: 31 AGTVPSEPPSACASDPCAPGTECQATESGGYTCGP---MEPRGCATQPCHHGALCVPQGP 87
AG P P C + A C T GGYT GP + C PC +G C
Sbjct: 815 AGPAPCGPHGICTN--LAGSFSC--TCHGGYT-GPSCDQDINDCDPNPCLNGGSC----Q 865
Query: 88 DPTG-FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME 146
D G F C C+PGF GPRC D+DEC S PC G TC + + C CP GY G CE +
Sbjct: 866 DGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVASFTCTCPPGYGGFHCEQD 924
Query: 147 VDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF 206
+ +C+ + C +GG+C+DGV SF C+C PGY G CQ + D C S+PC HGG C GF
Sbjct: 925 LPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGF 984
Query: 207 RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECA 266
RC C + + G C+ V C+ PC++ C++ G++ CLC PG+SG LC++ C
Sbjct: 985 RCTCLES-FTGPQCQTLVDWCSRQPCQNGGRCVQ-TGAY-CLCPPGWSGRLCDIRSLPCR 1041
Query: 267 SSP----------CQHGGRCL--------------------QRSDPALYGGVQAAFPGAF 296
+ CQ GG+C+ Q DP L Q G
Sbjct: 1042 EAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCL---AQPCQHGGT 1098
Query: 297 SFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE 356
+ G++C C PG+ G +C +VDECAS+PC +GG C DL + C CP G G CE
Sbjct: 1099 CRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCE 1158
Query: 357 EDVDECLSDP-------CLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAA 409
+ D+C P CLH GTC D V G+ C CP + G C + C+ C A
Sbjct: 1159 INEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAH 1218
Query: 410 TCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSVMAGSPIQ---ASVPAGGPLG 460
T + + G + C C G GP C T S P Q P+ GP G
Sbjct: 1219 TRDCLQDPG-GGFRCLCHAGFSGPRC--QTVLSPCESQPCQHGGQCRPSPGPGG 1269
Score = 270 bits (691), Expect = 5e-72
Identities = 143/434 (32%), Positives = 202/434 (46%), Gaps = 66/434 (15%)
Query: 34 VPSEPPSACASD-PCAPGTE-----CQATESGGYTCGPMEPRGCATQPCHHGALCVPQGP 87
+P PS+C + C G C+ +G + +P C ++PC HG +C P
Sbjct: 925 LPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADP--CLSRPCLHGGVCSAAHP 982
Query: 88 DPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEV 147
GFRC C+ F GP+C+ +D C+ +PC +G C + C CP G++G C++
Sbjct: 983 ---GFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC--VQTGAYCLCPPGWSGRLCDIRS 1037
Query: 148 DECASAP----------CLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGG 197
C A C GG C+D S CVC G G+ C+ ++D C +QPC HGG
Sbjct: 1038 LPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGG 1097
Query: 198 TCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGEL 257
TC + G+ C+C GY G +CE +V ECAS PC+H SC++ + + C C PG G L
Sbjct: 1098 TCRGYMGGYMCECL-PGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVL 1156
Query: 258 CEVDEDECASSP-------CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPP 310
CE++ED+C P C H G C+ GF C CPP
Sbjct: 1157 CEINEDDCGPGPPLDSGPRCLHNGTCVDL---------------------VGGFRCTCPP 1195
Query: 311 GFEGADCGVEVDECASRPCLNGGHC----QDLPNGFQCHCPDGYAGPTCEEDVDECLSDP 366
G+ G C +++EC S C + H QD GF+C C G++GP C+ + C S P
Sbjct: 1196 GYTGLRCEADINECRSGAC-HAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQP 1254
Query: 367 CLHGGTCSDTVAG-----YICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHS 421
C HGG C + + C C + + G C C+ CP+ C +
Sbjct: 1255 CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPC----QQTPRG 1310
Query: 422 YVCHCPPGTHGPFC 435
C CPPG GP C
Sbjct: 1311 PRCACPPGLSGPSC 1324
Score = 266 bits (679), Expect = 1e-70
Identities = 191/657 (29%), Positives = 268/657 (40%), Gaps = 108/657 (16%)
Query: 6 PGTPDPQALASVLLLLLWAPALSLLAGTVPSEPPSACASDPCAPGTECQATESGGYTCGP 65
P P P A LLLLL P A+ PC G+ C + G C
Sbjct: 17 PPPPPPPVRALPLLLLLAGPG---------------AAAPPCLDGSPC----ANGGRCTQ 57
Query: 66 MEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRN 125
+ R A C C PG+ G RC+L+ D C S PC C++
Sbjct: 58 LPSREAA---------------------CLCPPGWVGERCQLE-DPCHSGPCAGRGVCQS 95
Query: 126 L----ADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGV-GSFRCVCAPGYGGTR 180
R+ C CP G+ G C + D C S+PC HG C G G F C C PGY G
Sbjct: 96 SVVAGTARFSCRCPRGFRGPDCSLP-DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRS 154
Query: 181 CQLDLDECQ-SQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCL 239
C+ D+DEC+ +PC HGGTC + FRC C GY G CE + CA +PC + +C
Sbjct: 155 CRSDVDECRVGEPCRHGGTCLNTPGSFRCQCP-AGYTGPLCENPAVPCAPSPCRNGGTCR 213
Query: 240 E-GLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSF 298
+ G ++ C C PG+ G+ CEV+ D+C C +GG C+ GV
Sbjct: 214 QSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVD--------GVNT-------- 257
Query: 299 RHAAGFLCHCPPGFEGADCGVEVDECASRP--CLNGGHCQDLPNGFQCHCPDGYAGPTCE 356
+ C CPP + G C +VDEC +P C NGG C + G C C +G+ G +C
Sbjct: 258 -----YNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS 312
Query: 357 EDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFE 416
+++D+C + C HG TC D VA + C CP G C + C + C A C
Sbjct: 313 QNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPV 371
Query: 417 SGVHSYVCHCPPGTHGPFCGQNTTFSVMAGSPIQASVPAGGPLGLALRFRTTLPAGTLAT 476
+G +C CPPG G C Q+ + +P + G + F G
Sbjct: 372 NG--RAICTCPPGFTGGACDQDVDECSIGANPCE---HLGRCVNTQGSFLCQCGRGYTGP 426
Query: 477 RNDTKESLELALVAATLQATLWSYSTTVLVLRLPDLALNDGHWHQVEVVLHLATLELRLW 536
R +T + E QAT + + G + +V++
Sbjct: 427 RCETDVN-ECLSGPCRNQATCLDRIGQFTCICMAGFT---GTYCEVDI------------ 470
Query: 537 HEGCPARLCVASGPVALASTASATPLPAGISSA----QLGDATFAGCLQDVRV----DGH 588
+ C + CV G + P+G S + + + C + DG+
Sbjct: 471 -DECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGY 529
Query: 589 LLLPEDLGENVLLGCERR-EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
+ E L C+R + C P PC H G CVD F C CA + G C ++
Sbjct: 530 ECRCAEGFEGTL--CDRNVDDCSPDPC-HHGRCVDGIASFSCACAPGYTGTRCESQV 583
Score = 261 bits (666), Expect = 4e-69
Identities = 148/407 (36%), Positives = 181/407 (44%), Gaps = 58/407 (14%)
Query: 42 CASDPCAPGTECQATESGGYTCGPMEPRG----CATQPCHHGA---------LCVPQGP- 87
C+ PC G C ++G Y P G + PC A LC G
Sbjct: 1004 CSRQPCQNGGRC--VQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQC 1061
Query: 88 --DPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEM 145
+ + C C G G CE ++D C ++PC HG TCR Y C C GY G CE
Sbjct: 1062 VDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCED 1121
Query: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQP-------CAHGGT 198
+VDECAS PC HGGSC+D V + C C PG G C+++ D+C P C H GT
Sbjct: 1122 DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGT 1181
Query: 199 CHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCE--HNASCLEGL-GSFRCLCWPGYSG 255
C DLV GFRC C GY G CE ++ EC S C H CL+ G FRCLC G+SG
Sbjct: 1182 CVDLVGGFRCTCP-PGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSG 1240
Query: 256 ELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGA 315
C+ C S PCQHGG+C R P GG+ F CHC F G
Sbjct: 1241 PRCQTVLSPCESQPCQHGGQC--RPSPGPGGGLT--------------FTCHCAQPFWGP 1284
Query: 316 DCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEE--------DVDECLSDPC 367
C C C G CQ P G +C CP G +GP+C C + PC
Sbjct: 1285 RCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPC 1344
Query: 368 LHGGTC--SDTVAGYICRCPETWGGRDCSVQLTG---CQGHTCPLAA 409
LHGG+C + + C C + W G C + CP AA
Sbjct: 1345 LHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAA 1391
Score = 127 bits (318), Expect = 9e-29
Identities = 78/208 (37%), Positives = 90/208 (43%), Gaps = 50/208 (24%)
Query: 1045 PGTPAPILGCRGAPVCAPSPCLHDGACRDLFDA-FACACGPGWEGPRCEAHVDPCHSAPC 1103
PG AP P SPC + G C L AC C PGW G RC+ DPCHS PC
Sbjct: 36 PGAAAP-------PCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPC 87
Query: 1104 A-RGRCHTHP---DGRFECRCPPGFGGPRCRLPVP------------------------- 1134
A RG C + RF CRCP GF GP C LP P
Sbjct: 88 AGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCP 147
Query: 1135 ----SKECSLNV-TCLDGSPCEGGSPAAN------CSCLEGLAGQRCQVPTLPCEANPCL 1183
+ C +V C G PC G N C C G G C+ P +PC +PC
Sbjct: 148 PGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCR 207
Query: 1184 NGGTCRAAGGVS-ECICNARFSGQFCEV 1210
NGGTCR +G ++ +C C F GQ CEV
Sbjct: 208 NGGTCRQSGDLTYDCACLPGFEGQNCEV 235
Score = 125 bits (313), Expect = 3e-28
Identities = 66/193 (34%), Positives = 86/193 (44%), Gaps = 43/193 (22%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C P+PCL+ G+C+D +F+C+C PG+ GPRC VD C S PC G C H F C
Sbjct: 853 CDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHV-ASFTCT 911
Query: 1120 CPPGFGGPRCRLPVPSKECS-------------------------------------LNV 1142
CPPG+GG C +P +CS L+
Sbjct: 912 CPPGYGGFHCEQDLP--DCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSR 969
Query: 1143 TCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNAR 1202
CL G C P C+CLE G +CQ C PC NGG C G C+C
Sbjct: 970 PCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAY--CLCPPG 1027
Query: 1203 FSGQFCEVAKGLP 1215
+SG+ C++ + LP
Sbjct: 1028 WSGRLCDI-RSLP 1039
Score = 113 bits (283), Expect = 1e-24
Identities = 68/197 (34%), Positives = 82/197 (41%), Gaps = 43/197 (21%)
Query: 1054 CRGAPVCAPSPCLHDGACRDLFDA----FACACGPGWEGPRCEAHVDPCHSAPCARG-RC 1108
C+ C PC G C+ A F+C C G+ GP C DPC S+PCA G RC
Sbjct: 76 CQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP-DPCLSSPCAHGARC 134
Query: 1109 HTHPDGRFECRCPPGFGGPRCRLPVPS----KECSLNVTCLDG----------------- 1147
PDGRF C CPPG+ G CR V + C TCL+
Sbjct: 135 SVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLC 194
Query: 1148 ---------SPCEGGSPAA-------NCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAA 1191
SPC G +C+CL G GQ C+V C + CLNGGTC
Sbjct: 195 ENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDG 254
Query: 1192 GGVSECICNARFSGQFC 1208
C C ++GQFC
Sbjct: 255 VNTYNCQCPPEWTGQFC 271
Score = 110 bits (274), Expect = 1e-23
Identities = 57/151 (37%), Positives = 71/151 (47%), Gaps = 9/151 (5%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDG--RFE 1117
C PC H G C DL D + C C G G CE ++D C S PC G C DG R++
Sbjct: 586 CRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCR---DGINRYD 642
Query: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
C C PGF GP C + + EC+ + C +G C G C C G C P+ PC
Sbjct: 643 CVCQPGFTGPLCNVEI--NECA-SSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPC 699
Query: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
PC + G C A G C+C +SG C
Sbjct: 700 AHEPC-SHGICYDAPGGFRCVCEPGWSGPRC 729
Score = 108 bits (270), Expect = 3e-23
Identities = 57/152 (37%), Positives = 76/152 (50%), Gaps = 6/152 (3%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
C SPC++ G C+D + F+C C G+ G C+ VD C S PC G +C PDG +EC
Sbjct: 473 CQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDG-YEC 531
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
RC GF G C V +CS + C G C G + +C+C G G RC+ C
Sbjct: 532 RCAEGFEGTLCDRNV--DDCSPD-PCHHGR-CVDGIASFSCACAPGYTGTRCESQVDECR 587
Query: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
+ PC +GG C C C + +G CEV
Sbjct: 588 SQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEV 619
Score = 106 bits (264), Expect = 2e-22
Identities = 64/185 (34%), Positives = 75/185 (40%), Gaps = 12/185 (6%)
Query: 1056 GAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR---CHTHP 1112
G P+ + CLH+G C DL F C C PG+ G RCEA ++ C S C C P
Sbjct: 1167 GPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDP 1226
Query: 1113 DGRFECRCPPGFGGPRCRL---PVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQR 1169
G F C C GF GPRC+ P S+ C C SP GG C C + G R
Sbjct: 1227 GGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRP-SPGPGGGLTFTCHCAQPFWGPR 1285
Query: 1170 CQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGLPLPLPFPLLEVAVPA 1229
C+ C C G C+ C C SG C G P P A A
Sbjct: 1286 CERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSP-----PGASNASCA 1340
Query: 1230 ACACL 1234
A CL
Sbjct: 1341 AAPCL 1345
Score = 105 bits (263), Expect = 2e-22
Identities = 68/218 (31%), Positives = 90/218 (41%), Gaps = 47/218 (21%)
Query: 1039 EHFASWPGTPAPILG---C-RGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAH 1094
+H AS+ T P G C + P C+PS C + G C D ++F+C C PG+ G C+
Sbjct: 903 DHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE 962
Query: 1095 VDPCHSAPCARG---------------------RCHTHPD----------GRFE-----C 1118
DPC S PC G +C T D GR C
Sbjct: 963 ADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYC 1022
Query: 1119 RCPPGFGGPRCRL-PVPSKECSLNV------TCLDGSPCEGGSPAANCSCLEGLAGQRCQ 1171
CPPG+ G C + +P +E + + C G C + C C EG G C+
Sbjct: 1023 LCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCE 1082
Query: 1172 VPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
PC A PC +GGTCR G C C ++G CE
Sbjct: 1083 QEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCE 1120
Score = 105 bits (262), Expect = 3e-22
Identities = 59/187 (31%), Positives = 75/187 (40%), Gaps = 39/187 (20%)
Query: 1060 CA-PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFEC 1118
CA P+PC G C +L +F+C C G+ GP C+ ++ C PC G G F C
Sbjct: 814 CAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSC 873
Query: 1119 RCPPGFGGPRCRLPVPSKECSLN------------------------------------V 1142
C PGF GPRC V EC N
Sbjct: 874 SCLPGFAGPRCARDV--DECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPS 931
Query: 1143 TCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNAR 1202
+C +G C G + +C C G G CQ PC + PCL+GG C AA C C
Sbjct: 932 SCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLES 991
Query: 1203 FSGQFCE 1209
F+G C+
Sbjct: 992 FTGPQCQ 998
Score = 104 bits (260), Expect = 5e-22
Identities = 51/147 (34%), Positives = 69/147 (46%), Gaps = 3/147 (2%)
Query: 1063 SPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPP 1122
+PC H G C + +F C CG G+ GPRCE V+ C S PC G+F C C
Sbjct: 400 NPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMA 459
Query: 1123 GFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPC 1182
GF G C + + EC + C++G C+ +C+C G +G CQ+ C + PC
Sbjct: 460 GFTGTYCEVDI--DECQ-SSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPC 516
Query: 1183 LNGGTCRAAGGVSECICNARFSGQFCE 1209
NG C EC C F G C+
Sbjct: 517 RNGAKCVDQPDGYECRCAEGFEGTLCD 543
Score = 103 bits (258), Expect = 8e-22
Identities = 74/228 (32%), Positives = 89/228 (39%), Gaps = 54/228 (23%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C PC H G CR + C C PG+ G CE VD C S PC G R+ C
Sbjct: 1088 CLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCS 1147
Query: 1120 CPPGFGGPRCRL------PVP----SKECSLNVTCLD--------------GSPCE---- 1151
CPPG G C + P P C N TC+D G CE
Sbjct: 1148 CPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADIN 1207
Query: 1152 ----GGSPAAN-------------CSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAA--- 1191
G AA+ C C G +G RCQ PCE+ PC +GG CR +
Sbjct: 1208 ECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGP 1267
Query: 1192 -GGVS-ECICNARFSGQFCE-VAKG---LPLPLPFPLLEVAVPAACAC 1233
GG++ C C F G CE VA+ L P+ P + CAC
Sbjct: 1268 GGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCAC 1315
Score = 103 bits (257), Expect = 1e-21
Identities = 65/170 (38%), Positives = 76/170 (44%), Gaps = 12/170 (7%)
Query: 1045 PGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHV--DPCHSAP 1102
PG+ P+ P CA PC H G C D F C C PGW GPRC + D C S P
Sbjct: 685 PGSLPPLCLPPSHP-CAHEPCSH-GICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQP 742
Query: 1103 C-ARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGG-SPAANCS 1160
C A G C + G F C CPPG G +C L P C+ N C G CE CS
Sbjct: 743 CRAGGTCSSDGMG-FHCTCPPGVQGRQCELLSP---CTPN-PCEHGGRCESAPGQLPVCS 797
Query: 1161 CLEGLAGQRCQVPTLPCEA-NPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
C +G G RCQ C PC G C G C C+ ++G C+
Sbjct: 798 CPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCD 847
Score = 103 bits (257), Expect = 1e-21
Identities = 54/150 (36%), Positives = 69/150 (46%), Gaps = 4/150 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
C PC G C F C C PG +G +CE + PC PC G RC + P C
Sbjct: 738 CESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPGQLPVC 796
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
CP G+ GPRC+ V EC+ C C + + +C+C G G C C+
Sbjct: 797 SCPQGWQGPRCQQDVD--ECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCD 854
Query: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
NPCLNGG+C+ G C C F+G C
Sbjct: 855 PNPCLNGGSCQDGVGSFSCSCLPGFAGPRC 884
Score = 100 bits (250), Expect = 7e-21
Identities = 56/153 (36%), Positives = 72/153 (47%), Gaps = 7/153 (4%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
CA +PC G CRD + + C C PG+ GP C ++ C S+PC G + F C
Sbjct: 624 CASNPCTF-GVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCL 682
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRC--QVPTLPC 1177
CPPG P C LP PS C+ + C G C C C G +G RC + C
Sbjct: 683 CPPGSLPPLC-LP-PSHPCA-HEPCSHGI-CYDAPGGFRCVCEPGWSGPRCSQSLARDAC 738
Query: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
E+ PC GGTC + G C C G+ CE+
Sbjct: 739 ESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL 771
Score = 99.0 bits (245), Expect = 3e-20
Identities = 54/162 (33%), Positives = 75/162 (46%), Gaps = 9/162 (5%)
Query: 1054 CRGAPVCAPSPCLHDGAC--RDLFDAFACACGPGWEGPRCEAHVDPCH--SAPCAR-GRC 1108
C C +PC D C + C C PG+ G C+ VD C + PC GRC
Sbjct: 349 CHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRC 408
Query: 1109 HTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQ 1168
+ G F C+C G+ GPRC V EC L+ C + + C C C+ G G
Sbjct: 409 -VNTQGSFLCQCGRGYTGPRCETDV--NEC-LSGPCRNQATCLDRIGQFTCICMAGFTGT 464
Query: 1169 RCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
C+V C+++PC+NGG C+ C C + FSG C++
Sbjct: 465 YCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQL 506
Score = 98.2 bits (243), Expect = 4e-20
Identities = 52/153 (33%), Positives = 68/153 (44%), Gaps = 10/153 (6%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR-CHTHPDGRFEC 1118
C PC + C D F C C G+ G CE +D C S+PC G C +G F C
Sbjct: 435 CLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNG-FSC 493
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
CP GF G C+L V EC+ + C +G+ C C C EG G C C
Sbjct: 494 TCPSGFSGSTCQLDV--DECA-STPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCS 550
Query: 1179 ANPCLNGGTCRAAGGVS--ECICNARFSGQFCE 1209
+PC +G R G++ C C ++G CE
Sbjct: 551 PDPCHHG---RCVDGIASFSCACAPGYTGTRCE 580
Score = 95.1 bits (235), Expect = 4e-19
Identities = 51/153 (33%), Positives = 65/153 (42%), Gaps = 4/153 (2%)
Query: 1060 CAPSPCLHDGACRDLFD-AFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFEC 1118
CAPSPC + G CR D + CAC PG+EG CE +VD C C G + C
Sbjct: 201 CAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNC 260
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVT-CLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
+CPP + G C V EC L C +G C +C C+ G G+ C C
Sbjct: 261 QCPPEWTGQFCTEDVD--ECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDC 318
Query: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
C +G TC C C +G C +
Sbjct: 319 ATAVCFHGATCHDRVASFYCACPMGKTGLLCHL 351
Score = 92.8 bits (229), Expect = 2e-18
Identities = 58/194 (29%), Positives = 73/194 (37%), Gaps = 52/194 (26%)
Query: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR-------------- 1107
P+ C + G C + +C C GW G C ++D C +A C G
Sbjct: 282 PNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACP 341
Query: 1108 ------------------------CHTHP-DGRFECRCPPGFGGPRCRLPVPSKECSLNV 1142
C T+P +GR C CPPGF G C V ECS+
Sbjct: 342 MGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDV--DECSIG- 398
Query: 1143 TCLDGSPCEGGSPAAN------CSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSE 1196
+PCE N C C G G RC+ C + PC N TC G
Sbjct: 399 ----ANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFT 454
Query: 1197 CICNARFSGQFCEV 1210
CIC A F+G +CEV
Sbjct: 455 CICMAGFTGTYCEV 468
Score = 82.4 bits (202), Expect = 3e-15
Identities = 160/658 (24%), Positives = 204/658 (31%), Gaps = 157/658 (23%)
Query: 609 CRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC---ADEIPAATFGLGGAPSSASFLLQEL 665
C P C +GG+CVD F C C + G C AD + GG S+A
Sbjct: 928 CSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAH------ 981
Query: 666 PGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLS----EGRIRAEVPGSPAVVLPGRW 721
PG T L F L + S + R G+ + PG W
Sbjct: 982 PGFRCTC------------LESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPG-W 1028
Query: 722 DDGLRHLVMLSFGPDQLQ---DLGQHVHVGGRLLAADSQ-----PWGGPFRGCLQDLRLD 773
L + L Q L Q GG+ + DS P G C Q++ D
Sbjct: 1029 SGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEV--D 1086
Query: 774 GCHLPFFPLPLDNSSQPSELGGRQSWNLTA------------GCVSE-DMCSPDPCFNGG 820
C +QP + GG + C + D C+ PC +GG
Sbjct: 1087 PC-----------LAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGG 1135
Query: 821 TCLVTWNDFHCTCPANFTGPTCA--QQLWCPGQP------CLPPATCEEVPDGFVCVAEA 872
+C+ + C+CP G C + PG P CL TC ++ GF C
Sbjct: 1136 SCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTC-- 1193
Query: 873 TFREGPPAAFSGHN--ASSGRLLGGLSLAFRTRDSEAWLLRAAAGALEGVWLAVRNGSLA 930
P ++G A G A TRD L+ G + A +G
Sbjct: 1194 ------PPGYTGLRCEADINECRSGACHAAHTRDC----LQDPGGGFRCLCHAGFSGPRC 1243
Query: 931 GGVRGG-------HGLPGAVLPIPGPRVADGAWHRVRLAMERPAATTSRWLLWLDGAATP 983
V HG G P PGP G A R
Sbjct: 1244 QTVLSPCESQPCQHG--GQCRPSPGP--GGGLTFTCHCAQPFWGPRCER----------- 1288
Query: 984 VALRGLASDLGFLQGPGAVRILLAENFTGCLGRVALGGLPLPLARPRPGAAPGAREHFAS 1043
+A LQ P V C L G P R PG+ PGA
Sbjct: 1289 -----VARSCRELQCPVGVPCQQTPRGPRCACPPGLSG---PSCRSFPGSPPGASN---- 1336
Query: 1044 WPGTPAPILGCRGAPVCAPSPCLHDGACRD--LFDAFACACGPGWEGPRCEAHV---DPC 1098
CA +PCLH G+CR L F CAC GW GPRCEA +
Sbjct: 1337 --------------ASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVS 1382
Query: 1099 HSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAAN 1158
C R C R + RC P C +CSL+V G P
Sbjct: 1383 EEPRCPRAACQAK---RGDQRCDRECNSPGCGW--DGGDCSLSV----------GDPWRQ 1427
Query: 1159 CSCLE-------GLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
C L+ C P + C GG R V E C F+ C+
Sbjct: 1428 CEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCD 1485
Score = 73.2 bits (178), Expect = 2e-12
Identities = 45/154 (29%), Positives = 61/154 (39%), Gaps = 8/154 (5%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAP--CARGRCHTHPDGRFE 1117
C CL+ G C D + + C C P W G C VD C P C G + G
Sbjct: 240 CPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHS 299
Query: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
C C G+ G C + +C+ V C G+ C + C+C G G C + C
Sbjct: 300 CVCVNGWTGESCSQNI--DDCATAV-CFHGATCHDRVASFYCACPMGKTGLLCHLDD-AC 355
Query: 1178 EANPCLNGGTC--RAAGGVSECICNARFSGQFCE 1209
+NPC C G + C C F+G C+
Sbjct: 356 VSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD 389
Score = 63.9 bits (154), Expect = 9e-10
Identities = 46/146 (31%), Positives = 62/146 (42%), Gaps = 19/146 (13%)
Query: 732 SFGPDQLQDLGQHVHVGGRLLAADSQPWGGPFRGCLQDLR--LDGCHLPFFPLPLDNSSQ 789
S G + + LG+ V+ G L + + GP C D+ L G P N +
Sbjct: 396 SIGANPCEHLGRCVNTQGSFLCQCGRGYTGP--RCETDVNECLSG--------PCRNQAT 445
Query: 790 PSELGGRQSWNLTAGC------VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCA 843
+ G+ + AG V D C PC NGG C N F CTCP+ F+G TC
Sbjct: 446 CLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQ 505
Query: 844 QQL-WCPGQPCLPPATCEEVPDGFVC 868
+ C PC A C + PDG+ C
Sbjct: 506 LDVDECASTPCRNGAKCVDQPDGYEC 531
Score = 60.8 bits (146), Expect = 8e-09
Identities = 73/276 (26%), Positives = 97/276 (35%), Gaps = 40/276 (14%)
Query: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI------PAATFGLGGAPSSASFL 661
+C PC GGSCVD FRC C P C P + AP +
Sbjct: 660 ECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCV 719
Query: 662 LQE-LPGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPGR 720
+ GP + S ES AG G ++ G PG
Sbjct: 720 CEPGWSGPRCSQSLARDACES--------QPCRAG-------GTCSSDGMGFHCTCPPGV 764
Query: 721 WDDGLRHLVMLSFGPDQLQDLGQHVHVGGRL-LAADSQPWGGPFRGCLQDLRLDGCHLPF 779
G + ++ P+ + G+ G+L + + Q W GP C QD+ D C
Sbjct: 765 --QGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGP--RCQQDV--DECA--- 815
Query: 780 FPLPLDNSSQPSELGGRQSWNLTAGCVSEDM------CSPDPCFNGGTCLVTWNDFHCTC 833
P P + L G S G C P+PC NGG+C F C+C
Sbjct: 816 GPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSC 875
Query: 834 PANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVC 868
F GP CA+ + C PC P TC + F C
Sbjct: 876 LPGFAGPRCARDVDECLSNPC-GPGTCTDHVASFTC 910
Score = 56.2 bits (134), Expect = 2e-07
Identities = 59/203 (29%), Positives = 68/203 (33%), Gaps = 32/203 (15%)
Query: 1030 RPGAAPGAREHFASWPGTPAPILGC-RGAPVCAPSPCLHDGACRDLFDAFACACGPGWEG 1088
RP PG F P C R A C C C+ CAC PG G
Sbjct: 1262 RPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSG 1321
Query: 1089 PRCE--------AHVDPCHSAPCAR-GRCHTHPDGR-FECRCPPGFGGPRCRLPVPSKEC 1138
P C A C +APC G C P F C C G+ GPRC P + E
Sbjct: 1322 PSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEV 1381
Query: 1139 SLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPC-LNGGTCRAAGGVSEC 1197
S C P A C G QRC C + C +GG C + G
Sbjct: 1382 SEEPRC----------PRAACQAKRG--DQRCD---RECNSPGCGWDGGDCSLSVGDPWR 1426
Query: 1198 ICNA-----RFSGQFCEVAKGLP 1215
C A F+ C+ A P
Sbjct: 1427 QCEALQCWRLFNNSRCDPACSSP 1449
Score = 52.4 bits (124), Expect = 3e-06
Identities = 23/52 (44%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Query: 814 DPCFNGGTCLVTWNDFHCTCPANFTGPTCAQ-QLWCPGQPCLPPATCEEVPD 864
+PC +GGTCL T F C CPA +TGP C + C PC TC + D
Sbjct: 166 EPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGD 217
Score = 51.6 bits (122), Expect = 5e-06
Identities = 76/290 (26%), Positives = 94/290 (32%), Gaps = 87/290 (30%)
Query: 603 CERREQCRPLPCVHGGSC----VDLWTHFRCDCARPHRGPTCADEIPAATFGLGGAPSSA 658
C+ + C PC G C V F C C R RGP C+
Sbjct: 76 CQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCS----------------- 118
Query: 659 SFLLQELPGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLP 718
LP P L+ R S G +GR P P
Sbjct: 119 ------LPDPCLSSPCAHGARCSVG-----------------PDGRFLCSCP-------P 148
Query: 719 GRWDDGLRHLVMLSFGPDQLQDLGQHVHVGGRLLAADSQPWGGPFRGCLQDLRLDG--CH 776
G R V D+ + +G+ GG L G FR C G C
Sbjct: 149 GYQGRSCRSDV------DECR-VGEPCRHGGTCLNTP-----GSFR-CQCPAGYTGPLCE 195
Query: 777 LPFFPLPLDNSSQPSELGG--RQSWNLTAGC------------VSEDMCSPDPCFNGGTC 822
P P + P GG RQS +LT C V+ D C C NGGTC
Sbjct: 196 NPAVPC----APSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTC 251
Query: 823 LVTWNDFHCTCPANFTGPTCAQQL-WCPGQP--CLPPATCEEVPDGFVCV 869
+ N ++C CP +TG C + + C QP C TC G CV
Sbjct: 252 VDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCV 301
Score = 49.3 bits (116), Expect = 2e-05
Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 9/75 (12%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
C PC N TCL F C C A FTG C + C PC+ C++ +GF C
Sbjct: 435 CLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCT 494
Query: 870 AEATFREGPPAAFSG 884
P+ FSG
Sbjct: 495 C--------PSGFSG 501
Score = 48.9 bits (115), Expect = 3e-05
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D CSPDPC +G C+ F C C +TG C Q+ C QPC C ++ D ++
Sbjct: 547 DDCSPDPCHHG-RCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYL 605
Query: 868 C 868
C
Sbjct: 606 C 606
Score = 48.5 bits (114), Expect = 4e-05
Identities = 38/131 (29%), Positives = 48/131 (36%), Gaps = 28/131 (21%)
Query: 759 WGGPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELGGRQS-----WNLTAG-------CV 806
W GP C Q L D C SQP GG S ++ T C
Sbjct: 724 WSGP--RCSQSLARDACE-----------SQPCRAGGTCSSDGMGFHCTCPPGVQGRQCE 770
Query: 807 SEDMCSPDPCFNGGTCLVTWNDFH-CTCPANFTGPTCAQQL-WCPG-QPCLPPATCEEVP 863
C+P+PC +GG C C+CP + GP C Q + C G PC P C +
Sbjct: 771 LLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLA 830
Query: 864 DGFVCVAEATF 874
F C +
Sbjct: 831 GSFSCTCHGGY 841
Score = 47.8 bits (112), Expect = 7e-05
Identities = 70/288 (24%), Positives = 89/288 (30%), Gaps = 61/288 (21%)
Query: 603 CERREQCRPLPCVHGGSC-VDLWTHFRCDCARPHRGPTCADEIPAATFGLGGAPSSASFL 661
C + C PC HG C V F C C ++G +C ++ G P
Sbjct: 117 CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVG---EPCRHGGT 173
Query: 662 LQELPGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPGRW 721
PG F AG T L E P P P R
Sbjct: 174 CLNTPG-------------------SFRCQCPAGYTGPLCEN------PAVPCAPSPCRN 208
Query: 722 DDGLRHLVMLSFGPDQLQDL-GQHVHV------GGRLLAADS-------------QPWGG 761
R L++ L GQ+ V G R L + W G
Sbjct: 209 GGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTG 268
Query: 762 PFRGCLQDLRLDGCHLPFFPLPLDNSSQP-SELGGRQ-----SWNLTAGCVSEDMCSPDP 815
F C +D+ D C L P N + LGG W + + D C+
Sbjct: 269 QF--CTEDV--DECQLQ--PNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAV 322
Query: 816 CFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVP 863
CF+G TC F+C CP TG C C PC A C+ P
Sbjct: 323 CFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNP 370
Score = 47.8 bits (112), Expect = 7e-05
Identities = 23/62 (37%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLW-CPGQPCLPPATCEEVPDGFVCV 869
C+ PC GG+C+ N F C CP P C C +PC C + P GF CV
Sbjct: 661 CASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPC-SHGICYDAPGGFRCV 719
Query: 870 AE 871
E
Sbjct: 720 CE 721
Score = 46.2 bits (108), Expect = 2e-04
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 5/78 (6%)
Query: 802 TAGCVSEDM--CS--PDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPP 856
T G +D+ CS +PC + G C+ T F C C +TGP C + C PC
Sbjct: 384 TGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQ 443
Query: 857 ATCEEVPDGFVCVAEATF 874
ATC + F C+ A F
Sbjct: 444 ATCLDRIGQFTCICMAGF 461
Score = 44.3 bits (103), Expect = 8e-04
Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
V+ D C+ +PC G C N + C C FTGP C ++ C PC +C + +
Sbjct: 619 VNIDDCASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGEN 677
Query: 865 GFVCV 869
GF C+
Sbjct: 678 GFRCL 682
Score = 43.9 bits (102), Expect = 0.001
Identities = 75/292 (25%), Positives = 96/292 (32%), Gaps = 40/292 (13%)
Query: 609 CRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCA-----DEIPAATFGLGGAPSSASFLLQ 663
C PC HG C D FRC C GP C+ D + GG SS
Sbjct: 699 CAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGM--- 754
Query: 664 ELPGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPGRWDD 723
G + T ++ R+ L N G GR + P P W
Sbjct: 755 ---GFHCTCPPGVQGRQCELLSPCTPNPCEHG-------GRCESAPGQLPVCSCPQGWQG 804
Query: 724 G-LRHLVMLSFGPDQLQDLGQHVHVGGRLLAADSQPWGGPFRGCLQDLRLDGCHLPFFPL 782
+ V GP G ++ G + GP C QD+ + C P
Sbjct: 805 PRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGP--SCDQDI--NDCD----PN 856
Query: 783 PLDNSSQPSELGGRQSWNLTAG-----CVSE-DMCSPDPCFNGGTCLVTWNDFHCTCPAN 836
P N + G S + G C + D C +PC GTC F CTCP
Sbjct: 857 PCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTCTDHVASFTCTCPPG 915
Query: 837 FTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGHNA 887
+ G C Q L C C TC + + F C+ R G A H A
Sbjct: 916 YGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLC----RPGYTGAHCQHEA 963
Score = 43.1 bits (100), Expect = 0.002
Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 3/73 (4%)
Query: 805 CVSEDMCSPDPCFNGGTCLVTWND-FHCTCPANFTGPTCAQQL--WCPGQPCLPPATCEE 861
C D C PC +G C V + F C+CP + G +C + G+PC TC
Sbjct: 117 CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLN 176
Query: 862 VPDGFVCVAEATF 874
P F C A +
Sbjct: 177 TPGSFRCQCPAGY 189
Score = 41.6 bits (96), Expect = 0.005
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 805 CVSE-DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEV 862
C S+ D C PC +GG CL + + C CP+ TG C + C PC C +
Sbjct: 579 CESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPC-TFGVCRDG 637
Query: 863 PDGFVCVAEATF 874
+ + CV + F
Sbjct: 638 INRYDCVCQPGF 649
Score = 38.5 bits (88), Expect = 0.042
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
++C PC HGGSC+DL + C C G C
Sbjct: 1124 DECASQPCQHGGSCIDLVARYLCSCPPGTLGVLC 1157
Score = 37.4 bits (85), Expect = 0.093
Identities = 14/43 (32%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 603 CERR-EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
CE+ + C PC HGG+C + C+C + G C D++
Sbjct: 1081 CEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDV 1123
Score = 37.0 bits (84), Expect = 0.12
Identities = 14/34 (41%), Positives = 16/34 (47%)
Query: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
+ C PC+HGG C FRC C GP C
Sbjct: 964 DPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQC 997
Score = 36.2 bits (82), Expect = 0.21
Identities = 23/86 (26%), Positives = 30/86 (34%), Gaps = 5/86 (5%)
Query: 804 GCVSEDMCSPDPCFNGGTCL-VTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEV 862
G + PC NGG C + + C CP + G C + C PC C+
Sbjct: 37 GAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQ-- 94
Query: 863 PDGFVCVAEATFREGPPAAFSGHNAS 888
V A F P F G + S
Sbjct: 95 --SSVVAGTARFSCRCPRGFRGPDCS 118
Score = 36.2 bits (82), Expect = 0.21
Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 4/66 (6%)
Query: 603 CERREQCRPLPCVHGGSCVDLWTHFR-CDCARPHRGPTCADEIPAATFGLGGAPSSASFL 661
CE C P PC HGG C C C + +GP C ++ G AP +
Sbjct: 769 CELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECA---GPAPCGPHGI 825
Query: 662 LQELPG 667
L G
Sbjct: 826 CTNLAG 831
Score = 36.2 bits (82), Expect = 0.21
Identities = 20/50 (40%), Positives = 24/50 (48%), Gaps = 8/50 (16%)
Query: 603 CERREQ-CRPLP-------CVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
CE E C P P C+H G+CVDL FRC C + G C +I
Sbjct: 1157 CEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADI 1206
Score = 35.4 bits (80), Expect = 0.35
Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 1/46 (2%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPC 853
D C+ PC NG C+ + + C C F G C + + C PC
Sbjct: 509 DECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPC 554
Score = 35.0 bits (79), Expect = 0.46
Identities = 20/69 (28%), Positives = 25/69 (36%), Gaps = 5/69 (7%)
Query: 805 CVSEDMCSPDPCFNGGTCLVTWNDFH--CTCPANFTGPTCAQ---QLWCPGQPCLPPATC 859
C +D C +PC C + CTCP FTG C Q + PC C
Sbjct: 349 CHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRC 408
Query: 860 EEVPDGFVC 868
F+C
Sbjct: 409 VNTQGSFLC 417
Score = 33.1 bits (74), Expect = 1.8
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 6/38 (15%)
Query: 603 CERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
C+ QCRP P GG F C CA+P GP C
Sbjct: 1255 CQHGGQCRPSPGPGGGLT------FTCHCAQPFWGPRC 1286
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 325 bits (833), Expect = 2e-88
Identities = 165/415 (39%), Positives = 211/415 (50%), Gaps = 29/415 (6%)
Query: 42 CASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHG---ALCVPQGPDPT-------- 90
C S PC +C G T +P G + CH L QGP P
Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQP-GYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 454
Query: 91 ---GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEV 147
F C C PG+ G RCE D +EC S+PCH G+TC +L + C CP G G CE+E
Sbjct: 455 TPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVET 514
Query: 148 DECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFR 207
+ECASAPCL+ C D + F+C+C PG+ GTRC+ D+DEC+S PCA+GG C D F
Sbjct: 515 NECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFH 574
Query: 208 CDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECAS 267
C C G+EG C+ EV EC S PC ASCL+ G+F CLC G++G+LCEV CA
Sbjct: 575 CKCL-PGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEV--PLCAP 631
Query: 268 SPCQHGGRCLQRSDPALY----GGVQAAFPG---AFSFRHAAGFLCHCPPGFEGADCGVE 320
+ CQ C + D A G A P H C C G+ G +C E
Sbjct: 632 NLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAE 691
Query: 321 VDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGY 380
+ C S PC +GG C P+G+ C CP GY GPTC E++ C S PCL+GG+C+ + GY
Sbjct: 692 LGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGY 751
Query: 381 ICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
C CP + G C C C TC+ + ++ C C G GP C
Sbjct: 752 YCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCV----NRPGTFSCLCAMGFQGPRC 802
Score = 303 bits (777), Expect = 5e-82
Identities = 167/455 (36%), Positives = 208/455 (45%), Gaps = 99/455 (21%)
Query: 46 PCAPGTECQATESGGYTC---------------GPMEPRGCATQPCHHGALC--VPQGPD 88
PC GT C T G + C GP PRGC+ +G C +P+ D
Sbjct: 204 PCPKGTSCHNT-LGSFQCLCPVGQEGPRCELRAGPCPPRGCS-----NGGTCQLMPE-KD 256
Query: 89 PTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCP------------- 135
T C C PGF GP CE++ D C S C +G TC++ D Y C CP
Sbjct: 257 STFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVD 316
Query: 136 ----------------------------LGYAGVTCEMEVDECASAPCLHGGSCLDGVGS 167
G+ G +CE +D+C +A C G +C+D VGS
Sbjct: 317 ECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGS 376
Query: 168 FRCVCAPGYGGTRCQLDLDECQSQPCAHGGTC--HDLVNGFRCDCAGTGYEGTHCEREVL 225
F C+C PG G C L+ D C SQPC C + L C C GY G C +++
Sbjct: 377 FSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQ-PGYSGPTCHQDLD 434
Query: 226 ECASA-----PCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRS 280
EC A PCEH SCL GSF CLC PGY+G CE D +EC S PC G CL
Sbjct: 435 ECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDL- 493
Query: 281 DPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPN 340
A F C CPPG EG C VE +ECAS PCLN C DL N
Sbjct: 494 --------------------LATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLN 533
Query: 341 GFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGC 400
GFQC C G++G CEED+DEC S PC +GG C D + C+C + G C ++ C
Sbjct: 534 GFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDEC 593
Query: 401 QGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
CP+ A+C+ + ++ C CP G G C
Sbjct: 594 LSDPCPVGASCLDL----PGAFFCLCPSGFTGQLC 624
Score = 301 bits (772), Expect = 2e-81
Identities = 155/427 (36%), Positives = 204/427 (47%), Gaps = 48/427 (11%)
Query: 40 SACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPG 99
S+C D G EC+A E GC + PC HG C PQ P+G+ C C G
Sbjct: 675 SSCVCDVGWTGPECEA-----------ELGGCISAPCAHGGTCYPQ---PSGYNCTCPTG 720
Query: 100 FQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGG 159
+ GP C ++ C S PC +G +C Y C CP + G C+ D C SAPC +GG
Sbjct: 721 YTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGG 780
Query: 160 SCLDGVGSFRCVCAPGYGGTRCQLDL-DECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGT 218
+C++ G+F C+CA G+ G RC+ L C PC + TC D G RC C TGY G
Sbjct: 781 TCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCP-TGYTGG 839
Query: 219 HCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDEC----------ASS 268
C+ + CA PC N+ CL+ SF CLC G++G LC + C SS
Sbjct: 840 SCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSS 899
Query: 269 PCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHA------------------AGFLCHCPP 310
C +GG C+ S P+ + F G+ H +G+LC C P
Sbjct: 900 LCHNGGLCVD-SGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAP 958
Query: 311 GFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHG 370
G++G +C E+D C S+PC N G C P GF C CP G+ G CE DVDECL PC
Sbjct: 959 GYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPT 1018
Query: 371 GT--CSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPP 428
GT C + C+C G+ C V++ C C TC S + ++CHCP
Sbjct: 1019 GTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL-GFICHCPK 1077
Query: 429 GTHGPFC 435
G GP C
Sbjct: 1078 GFEGPTC 1084
Score = 288 bits (736), Expect = 3e-77
Identities = 156/429 (36%), Positives = 196/429 (45%), Gaps = 51/429 (11%)
Query: 32 GTVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRG---------CATQPCHHGALC 82
G SE +AC S PC G C + G Y P G C + PC +G C
Sbjct: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC 782
Query: 83 VPQGPDPTGFRCYCVPGFQGPRCELDI-DECASRPCHHGATCRNLADRYECHCPLGYAGV 141
V + P F C C GFQGPRCE + CA PC + ATC++ C CP GY G
Sbjct: 783 VNR---PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGG 839
Query: 142 TCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQ----------SQ 191
+C+ +D CA PC CL SF C+C G+ G C L L CQ S
Sbjct: 840 SCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSS 899
Query: 192 PCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWP 251
C +GG C D + C C G++G+ C+ V C S PC++ A+C+ + C C P
Sbjct: 900 LCHNGGLCVDSGPSYFCHCP-PGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAP 958
Query: 252 GYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPG 311
GY G+ C + D C S PC + G C + PG GF C CPPG
Sbjct: 959 GYDGQNCSKELDACQSQPCHNHGTCTPK-------------PG--------GFHCACPPG 997
Query: 312 FEGADCGVEVDECASRPCLNGG--HCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLH 369
F G C +VDEC +PC G C L N F C C G+ G CE ++D C S PC H
Sbjct: 998 FVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFH 1057
Query: 370 GGTCSDTVA---GYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHC 426
GGTC T G+IC CP+ + G CS + C H C C+P + G C C
Sbjct: 1058 GGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPR-CAC 1116
Query: 427 PPGTHGPFC 435
G GP C
Sbjct: 1117 LSGYGGPDC 1125
Score = 256 bits (655), Expect = 7e-68
Identities = 148/446 (33%), Positives = 191/446 (42%), Gaps = 103/446 (23%)
Query: 31 AGTVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPT 90
+GT E C S PCA G +CQ + G + C
Sbjct: 544 SGTRCEEDIDECRSSPCANGGQCQ-DQPGAFHC--------------------------- 575
Query: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEV--- 147
C+PGF+GPRC+ ++DEC S PC GA+C +L + C CP G+ G CE+ +
Sbjct: 576 ----KCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAP 631
Query: 148 ----------DECASAPCL-----------------HGGSCLDGVGSFRCVCAPGYGGTR 180
D+ A CL H G C CVC G+ G
Sbjct: 632 NLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS----SCVCDVGWTGPE 687
Query: 181 CQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLE 240
C+ +L C S PCAHGGTC+ +G+ C C TGY G C E+ C S PC + SC
Sbjct: 688 CEAELGGCISAPCAHGGTCYPQPSGYNCTCP-TGYTGPTCSEEMTACHSGPCLNGGSCNP 746
Query: 241 GLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRH 300
G + C C P ++G C+ D C S+PC +GG C+ R PG FS
Sbjct: 747 SPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR-------------PGTFS--- 790
Query: 301 AAGFLCHCPPGFEGADC-GVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDV 359
C C GF+G C G CA PC N CQD P G +C CP GY G +C+ +
Sbjct: 791 -----CLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLM 845
Query: 360 DECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQ----------GHTCPLAA 409
D C PC C T + C C + W G C++ L+ CQ C
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905
Query: 410 TCIPIFESGVHSYVCHCPPGTHGPFC 435
C+ +SG SY CHCPPG G C
Sbjct: 906 LCV---DSG-PSYFCHCPPGFQGSLC 927
Score = 245 bits (626), Expect = 2e-64
Identities = 148/452 (32%), Positives = 204/452 (45%), Gaps = 53/452 (11%)
Query: 21 LLWAPALSLLAGTVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQP-CHHG 79
LL AP L L + P P C P G CQA P P C+ + CH
Sbjct: 83 LLPAP-LGLPSSPSPLTPSFLCTCLPGFTGERCQAKLED-----PCPPSFCSKRGRCHIQ 136
Query: 80 ALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA 139
A PQ C C+PG+ G +C+L D C++ PC +G C + +CHCP G+
Sbjct: 137 ASGRPQ--------CSCMPGWTGEQCQLR-DFCSANPCVNGGVCLATYPQIQCHCPPGFE 187
Query: 140 GVTCEMEVDECAS--APCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGG 197
G CE +V+EC PC G SC + +GSF+C+C G G RC+L C + C++GG
Sbjct: 188 GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGG 247
Query: 198 TCH---DLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYS 254
TC + + F G+ G CE C S C++ +C +GL ++ CLC ++
Sbjct: 248 TCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT 307
Query: 255 GELCEVDEDECASS---PCQHGGRCLQRSDP------ALYGGVQ-----------AAFPG 294
G C D DEC + C++GG C + + +GG PG
Sbjct: 308 GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPG 367
Query: 295 AFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLP--NGFQCHCPDGYAG 352
+ F C CPPG G C +E D C S+PC C P C C GY+G
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSG 426
Query: 353 PTCEEDVDECL-----SDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPL 407
PTC +D+DECL PC HGG+C +T + C CP + G C C C
Sbjct: 427 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHP 486
Query: 408 AATCIPIFESGVHSYVCHCPPGTHGPFCGQNT 439
+TC+ + + ++ C CPPG G C T
Sbjct: 487 GSTCLDL----LATFHCLCPPGLEGQLCEVET 514
Score = 235 bits (599), Expect = 2e-61
Identities = 142/400 (35%), Positives = 182/400 (45%), Gaps = 60/400 (15%)
Query: 66 MEPRG--CAT--QPCHHGALCVP----QGPDPTGFRCYCVPGFQGPRCELDIDECA-SRP 116
+ PRG C + +PC +G C+ QG C C PGF G C+ D C ++
Sbjct: 21 VRPRGLLCGSFPEPCANGGTCLSLSLGQGT------CQCAPGFLGETCQFP-DPCQNAQL 73
Query: 117 CHHGATCR--------------NLADRYECHCPLGYAGVTCEMEV-DECASAPCLHGGSC 161
C +G +C+ L + C C G+ G C+ ++ D C + C G C
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRC 133
Query: 162 -LDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHC 220
+ G +C C PG+ G +CQL D C + PC +GG C +C C G+EG C
Sbjct: 134 HIQASGRPQCSCMPGWTGEQCQL-RDFCSANPCVNGGVCLATYPQIQCHCP-PGFEGHAC 191
Query: 221 EREVLECAS--APCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQ 278
ER+V EC PC SC LGSF+CLC G G CE+ C C +GG C
Sbjct: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTC-- 249
Query: 279 RSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDL 338
P S H LC CPPGF G DC V D C S C NGG CQD
Sbjct: 250 -----------QLMPEKDSTFH----LCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDG 294
Query: 339 PNGFQCHCPDGYAGPTCEEDVDECLSD---PCLHGGTCSDTVAGYICRCPETWGGRDCSV 395
+ + C CP+ + G C EDVDEC + C +GGTC ++ + C C WGG C
Sbjct: 295 LDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEE 354
Query: 396 QLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
L C TC +TCI V S+ C CPPG G C
Sbjct: 355 NLDDCIAATCAPGSTCI----DRVGSFSCLCPPGRTGLLC 390
Score = 222 bits (565), Expect = 2e-57
Identities = 137/408 (33%), Positives = 166/408 (40%), Gaps = 77/408 (18%)
Query: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCP 135
CH+G LCV GP + C+C PGFQG C+ ++ C SRPC +GATC Y C C
Sbjct: 901 CHNGGLCVDSGPS---YFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCA 957
Query: 136 LGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAH 195
GY G C E+D C S PC + G+C G F C C PG+ G RC+ D+DEC QPC
Sbjct: 958 PGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHP 1017
Query: 196 GGT--CHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGS---FRCLCW 250
GT CH L N F C C G+ G CE E+ C S PC H +C GS F C C
Sbjct: 1018 TGTAACHSLANAFYCQCL-PGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCP 1076
Query: 251 PGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPP 310
G+ G C C C HGG CL P FP C C
Sbjct: 1077 KGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKP--------GFPPR----------CACLS 1118
Query: 311 GFEGADC--GVEVDECA-SRPCLNGGHCQDLPN----GFQCHCPDGYAGPTCEEDVDECL 363
G+ G DC C PCL G C + GF+C CP GP C++
Sbjct: 1119 GYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQK------ 1172
Query: 364 SDPCLHG--GTCSDTVAGYICRCP-ETWGGRDCSVQL----TGCQGHT------------ 404
P G G D C P W G DCS+ + GC H+
Sbjct: 1173 --PGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCH 1230
Query: 405 --------------CPLAATCIPIFESGVHSYV--CHCPPGTHGPFCG 436
C C P ++ H + HC G + CG
Sbjct: 1231 PQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECG 1278
Score = 179 bits (454), Expect = 2e-44
Identities = 112/335 (33%), Positives = 150/335 (44%), Gaps = 63/335 (18%)
Query: 154 PCLHGGSCLD-GVGSFRCVCAPGYGGTRCQLDLDECQ-SQPCAHGGTCH----------- 200
PC +GG+CL +G C CAPG+ G CQ D CQ +Q C +GG+C
Sbjct: 34 PCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPS 92
Query: 201 ---DLVNGFRCDCAGTGYEGTHCEREVLE-CASAPCEHNASC-LEGLGSFRCLCWPGYSG 255
L F C C G+ G C+ ++ + C + C C ++ G +C C PG++G
Sbjct: 93 SPSPLTPSFLCTCL-PGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 151
Query: 256 ELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHA-------------- 301
E C++ D C+++PC +GG CL A Y +Q P F HA
Sbjct: 152 EQCQL-RDFCSANPCVNGGVCL-----ATYPQIQCHCPPGFE-GHACERDVNECFQDPGP 204
Query: 302 -----------AGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNG----FQCHC 346
F C CP G EG C + C R C NGG CQ +P C C
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
Query: 347 PDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGH--- 403
P G+ GP CE + D C+S C +GGTC D + Y C CPETW G DCS + C+
Sbjct: 265 PPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP 324
Query: 404 TCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438
C TC ++ S+ C C G G C +N
Sbjct: 325 HCRNGGTC----QNSAGSFHCVCVSGWGGTSCEEN 355
Score = 118 bits (296), Expect = 3e-26
Identities = 65/175 (37%), Positives = 83/175 (47%), Gaps = 5/175 (2%)
Query: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCP 1121
PSPC H G+C + +F C C PG+ G RCEA + C S PC G F C CP
Sbjct: 443 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCP 502
Query: 1122 PGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANP 1181
PG G C V + EC+ + CL+ + C C CL G +G RC+ C ++P
Sbjct: 503 PGLEGQLCE--VETNECA-SAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP 559
Query: 1182 CLNGGTCRAAGGVSECICNARFSGQFC--EVAKGLPLPLPFPLLEVAVPAACACL 1234
C NGG C+ G C C F G C EV + L P P + +P A CL
Sbjct: 560 CANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCL 614
Score = 117 bits (294), Expect = 5e-26
Identities = 60/152 (39%), Positives = 74/152 (48%), Gaps = 5/152 (3%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTHPDGRFEC 1118
C PC C DL F C C PG EG CE + C SAPC CH +G F+C
Sbjct: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNG-FQC 537
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
C PGF G RC + EC + C +G C+ A +C CL G G RCQ C
Sbjct: 538 ICLPGFSGTRCEEDID--ECRSS-PCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECL 594
Query: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
++PC G +C G C+C + F+GQ CEV
Sbjct: 595 SDPCPVGASCLDLPGAFFCLCPSGFTGQLCEV 626
Score = 114 bits (285), Expect = 6e-25
Identities = 59/141 (41%), Positives = 74/141 (52%), Gaps = 7/141 (4%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
CA +PCL+ C DL + F C C PG+ G RCE +D C S+PCA G +C P G F C
Sbjct: 517 CASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP-GAFHC 575
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
+C PGF GPRC+ V EC L+ C G+ C A C C G GQ C+VP C
Sbjct: 576 KCLPGFEGPRCQTEV--DEC-LSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL--CA 630
Query: 1179 ANPCLNGGTCRAAGGVSECIC 1199
N C C+ + C+C
Sbjct: 631 PNLCQPKQICKDQKDKANCLC 651
Score = 112 bits (281), Expect = 2e-24
Identities = 61/160 (38%), Positives = 76/160 (47%), Gaps = 16/160 (10%)
Query: 1056 GAPVCAPSP---CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTH 1111
G+P CAP H G C+ +C C GW GP CEA + C SAPCA G C+
Sbjct: 654 GSPGCAPPEDNCTCHHGHCQ----RSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ 709
Query: 1112 PDGRFECRCPPGFGGPRCRLPVPSKECSL--NVTCLDGSPCEGGSPAANCSCLEGLAGQR 1169
P G + C CP G+ GP C S+E + + CL+G C C+C G +
Sbjct: 710 PSG-YNCTCPTGYTGPTC-----SEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQ 763
Query: 1170 CQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
CQ T C + PC NGGTC G C+C F G CE
Sbjct: 764 CQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCE 803
Score = 112 bits (281), Expect = 2e-24
Identities = 70/192 (36%), Positives = 81/192 (42%), Gaps = 25/192 (13%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTHPDGRFEC 1118
C PC + C + C C PG++G C +D C S PC G C P G F C
Sbjct: 934 CESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGG-FHC 992
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTC--LDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP 1176
CPPGF G RC V EC L+ C + C + A C CL G GQ C+V P
Sbjct: 993 ACPPGFVGLRCEGDV--DEC-LDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDP 1049
Query: 1177 CEANPCLNGGTCRAAGGVS---ECICNARFSGQFCEVAK-----------GLPLPLPFPL 1222
C + PC +GGTC A G C C F G C GL LP P P
Sbjct: 1050 CHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKP- 1108
Query: 1223 LEVAVPAACACL 1234
P CACL
Sbjct: 1109 ---GFPPRCACL 1117
Score = 109 bits (273), Expect = 1e-23
Identities = 56/181 (30%), Positives = 78/181 (43%), Gaps = 10/181 (5%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
C +PC H G C + C C G+ GP C + CHS PC G C+ P G + C
Sbjct: 695 CISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYY-C 753
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP-C 1177
CPP GP+C+ S + ++ C +G C +C C G G RC+ P C
Sbjct: 754 TCPPSHTGPQCQ---TSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSC 810
Query: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGL----PLPLPFPLLEVAVPAACAC 1233
+PC N TC+ + C+C ++G C+ L P P L+ C C
Sbjct: 811 ADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLC 870
Query: 1234 L 1234
L
Sbjct: 871 L 871
Score = 103 bits (257), Expect = 1e-21
Identities = 55/164 (33%), Positives = 69/164 (42%), Gaps = 9/164 (5%)
Query: 1054 CRGA--PVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTH 1111
C G P CA SPC + C+D C C G+ G C+ +D C PC R
Sbjct: 802 CEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQ 861
Query: 1112 PDGRFECRCPPGFGGPRCRLPVP-------SKECSLNVTCLDGSPCEGGSPAANCSCLEG 1164
F C C G+ GP C LP+ S+ ++ C +G C P+ C C G
Sbjct: 862 TGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPG 921
Query: 1165 LAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
G CQ PCE+ PC NG TC A C C + GQ C
Sbjct: 922 FQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNC 965
Score = 102 bits (254), Expect = 2e-21
Identities = 61/186 (32%), Positives = 81/186 (43%), Gaps = 19/186 (10%)
Query: 1028 RPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWE 1087
RP+ PG W G C+ C+ +PC++ G C + C C PG+E
Sbjct: 140 RPQCSCMPG-------WTGEQ-----CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE 187
Query: 1088 GPRCEAHVDPCHS--APCARGRCHTHPDGRFECRCPPGFGGPRCRL---PVPSKECSLNV 1142
G CE V+ C PC +G + G F+C CP G GPRC L P P + CS
Sbjct: 188 GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGG 247
Query: 1143 TCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNAR 1202
TC E S C C G G C+V C ++ C NGGTC+ C+C
Sbjct: 248 TC--QLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPET 305
Query: 1203 FSGQFC 1208
++G C
Sbjct: 306 WTGWDC 311
Score = 101 bits (251), Expect = 5e-21
Identities = 54/155 (34%), Positives = 70/155 (45%), Gaps = 10/155 (6%)
Query: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTHP--DGRFE- 1117
P PC +C + +F C C G EGPRCE PC C+ G C P D F
Sbjct: 202 PGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHL 261
Query: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
C CPPGF GP C + + + ++ C +G C+ G C C E G C C
Sbjct: 262 CLCPPGFIGPDCEV---NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDEC 318
Query: 1178 EAN---PCLNGGTCRAAGGVSECICNARFSGQFCE 1209
E C NGGTC+ + G C+C + + G CE
Sbjct: 319 ETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCE 353
Score = 99.4 bits (246), Expect = 2e-20
Identities = 65/203 (32%), Positives = 88/203 (43%), Gaps = 12/203 (5%)
Query: 1022 LPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCA---PSPCLHDGACRDLFDAF 1078
L L L + APG +P C+ C P+P + L +F
Sbjct: 42 LSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSF 101
Query: 1079 ACACGPGWEGPRCEAHV-DPCHSAPCA-RGRCHTHPDGRFECRCPPGFGGPRCRLPVPSK 1136
C C PG+ G RC+A + DPC + C+ RGRCH GR +C C PG+ G +C+L
Sbjct: 102 LCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQL---RD 158
Query: 1137 ECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC--EANPCLNGGTCRAAGGV 1194
CS N C++G C P C C G G C+ C + PC G +C G
Sbjct: 159 FCSAN-PCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217
Query: 1195 SECICNARFSGQFCEVAKGLPLP 1217
+C+C G CE+ G P P
Sbjct: 218 FQCLCPVGQEGPRCELRAG-PCP 239
Score = 96.7 bits (239), Expect = 1e-19
Identities = 46/151 (30%), Positives = 62/151 (41%), Gaps = 2/151 (1%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C PCL+ G+C + C C P GP+C+ D C SAPC G + G F C
Sbjct: 733 CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCL 792
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
C GF GPRC + + + C + + C+ C C G G CQ C
Sbjct: 793 CAMGFQGPRCEGKL--RPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQ 850
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
PC C G C+C ++G C +
Sbjct: 851 KPCPRNSHCLQTGPSFHCLCLQGWTGPLCNL 881
Score = 96.7 bits (239), Expect = 1e-19
Identities = 89/309 (28%), Positives = 110/309 (35%), Gaps = 60/309 (19%)
Query: 42 CASDPCAP-GTE-CQATESGGYT-CGP--------MEPRGCATQPCHHGALCVPQGPDPT 90
C PC P GT C + + Y C P +E C +QPC HG C P
Sbjct: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL 1069
Query: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHGATC---RNLADRYECHCPLGYAGVTC--EM 145
GF C+C GF+GP C C CHHG C C C GY G C
Sbjct: 1070 GFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPP 1129
Query: 146 EVDECA-SAPCLHGGSCLDGVG----SFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCH 200
C +PCL+ GSC + G FRC C G RCQ +P A G C
Sbjct: 1130 APKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQ--------KPGAKG--CE 1179
Query: 201 DLVNGFRCD--CAGTG--YEGTHCEREVLECASAPCEHNASCLEGLGSFR-CLCWPGYSG 255
CD C+G G ++G C V + H+ L FR C P
Sbjct: 1180 GRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWL----LFRDGQCHPQCDS 1235
Query: 256 ELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGA 315
E C D +C + P A P + H HC G A
Sbjct: 1236 EECLFDGYDCETPP--------------------ACTPAYDQYCHDHFHNGHCEKGCNTA 1275
Query: 316 DCGVEVDEC 324
+CG + +C
Sbjct: 1276 ECGWDGGDC 1284
Score = 91.7 bits (226), Expect = 4e-18
Identities = 60/190 (31%), Positives = 72/190 (37%), Gaps = 41/190 (21%)
Query: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCP 1121
P C + G C++ +F C C GW G CE ++D C +A CA G G F C CP
Sbjct: 323 PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCP 382
Query: 1122 PGFGGPRCRLP--------VPSKECSLN-------VTCLDG------------------- 1147
PG G C L +CS N C G
Sbjct: 383 PGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQG 442
Query: 1148 -SPCE-GGS-----PAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICN 1200
SPCE GGS + NC C G G RC+ C + PC G TC C+C
Sbjct: 443 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCP 502
Query: 1201 ARFSGQFCEV 1210
GQ CEV
Sbjct: 503 PGLEGQLCEV 512
Score = 88.2 bits (217), Expect = 5e-17
Identities = 59/168 (35%), Positives = 72/168 (42%), Gaps = 27/168 (16%)
Query: 1062 PSPCLHDGACRDL-FDAFACACGPGWEGPRCEAHVDPCHSAPCAR--GRCHT---HPDG- 1114
P PC + G C L C C PG+ G C+ DPC +A + G C P G
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQ-FPDPCQNAQLCQNGGSCQALLPAPLGL 90
Query: 1115 ---------RFECRCPPGFGGPRCRL----PVPSKECSLNVTCLDGSPCEGGSPAANCSC 1161
F C C PGF G RC+ P P CS C + G P CSC
Sbjct: 91 PSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQA---SGRP--QCSC 145
Query: 1162 LEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
+ G G++CQ+ C ANPC+NGG C A +C C F G CE
Sbjct: 146 MPGWTGEQCQLRDF-CSANPCVNGGVCLATYPQIQCHCPPGFEGHACE 192
Score = 78.2 bits (191), Expect = 5e-14
Identities = 60/196 (30%), Positives = 64/196 (32%), Gaps = 58/196 (29%)
Query: 1029 PRPGAAPGAREHFASWPGTPAPILGCRG-APVCAPSPCLHDG--ACRDLFDAFACACGPG 1085
P+PG H A PG L C G C PC G AC L +AF C C PG
Sbjct: 985 PKPGGF-----HCACPPGFVG--LRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPG 1037
Query: 1086 WEGPRCEAHVDPCHSAPCARG------------------------------------RCH 1109
G CE +DPCHS PC G CH
Sbjct: 1038 HTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCH 1097
Query: 1110 --------THPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEG----GSPAA 1157
P C C G+GGP C P K C CL C G P
Sbjct: 1098 HGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGF 1157
Query: 1158 NCSCLEGLAGQRCQVP 1173
CSC G RCQ P
Sbjct: 1158 RCSCPHSSPGPRCQKP 1173
Score = 69.7 bits (169), Expect = 2e-11
Identities = 75/294 (25%), Positives = 113/294 (38%), Gaps = 34/294 (11%)
Query: 579 CLQDVRVDGHLLLPEDLGENVLLGCERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGP 638
CL D+ H L P L E L E E C PC++ C DL F+C C G
Sbjct: 490 CL-DLLATFHCLCPPGL-EGQLCEVETNE-CASAPCLNHADCHDLLNGFQCICLPGFSGT 546
Query: 639 TCADEIPAATFGLGGAPSSASFLLQELPGPNLTVSFLLRTRES-AGLLLQFANDSAAGLT 697
C ++I +P + Q+ PG +F + G Q D L+
Sbjct: 547 RCEEDIDECR----SSPCANGGQCQDQPG-----AFHCKCLPGFEGPRCQTEVDEC--LS 595
Query: 698 VFLSEGRIRAEVPGSPAVVLPGRWDDGLRHLVMLSFGPDQLQDLGQHVHVGGRLLAADSQ 757
G ++PG+ + P + L + + + Q + + + L D
Sbjct: 596 DPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGS 655
Query: 758 PWGGPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELG--GRQSWNLTAGCVSEDMCSPDP 815
P GC CH SS ++G G + GC+S P
Sbjct: 656 P------GCAPPEDNCTCHHGH----CQRSSCVCDVGWTGPECEAELGGCISA------P 699
Query: 816 CFNGGTCLVTWNDFHCTCPANFTGPTCAQQLW-CPGQPCLPPATCEEVPDGFVC 868
C +GGTC + ++CTCP +TGPTC++++ C PCL +C P G+ C
Sbjct: 700 CAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYC 753
Score = 61.2 bits (147), Expect = 6e-09
Identities = 77/284 (27%), Positives = 100/284 (35%), Gaps = 42/284 (14%)
Query: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIPAATFGLGGAPSSASFLLQELP 666
+ C PC +GG+CV+ F C CA +GP C ++ + +P Q+ P
Sbjct: 769 DYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSC---ADSPCRNRATCQDSP 825
Query: 667 -GPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPGRWDDGL 725
GP L+ A + L G P + L G W L
Sbjct: 826 QGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTG------PSFHCLCLQG-WTGPL 878
Query: 726 RHLVMLSFGPDQLQ---DLGQHVHVGGRLLAADSQP-----WGGPFRGCLQDLRLDGCHL 777
+L + S L D+ H GG L DS P F+G L ++ C
Sbjct: 879 CNLPLSSCQKAALSQGIDVSSLCHNGG--LCVDSGPSYFCHCPPGFQGSLCQDHVNPCE- 935
Query: 778 PFFPLPLDNSS----QPSEL-----GGRQSWNLTAGCVSE-DMCSPDPCFNGGTCLVTWN 827
P N + QPS G N C E D C PC N GTC
Sbjct: 936 ---SRPCQNGATCMAQPSGYLCQCAPGYDGQN----CSKELDACQSQPCHNHGTCTPKPG 988
Query: 828 DFHCTCPANFTGPTCAQQL-WCPGQPCLPPAT--CEEVPDGFVC 868
FHC CP F G C + C QPC P T C + + F C
Sbjct: 989 GFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYC 1032
Score = 60.8 bits (146), Expect = 8e-09
Identities = 29/73 (39%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Query: 807 SEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL--WCPGQPCLPPATCEEVPD 864
S D C PCFNGGTC+ F C C F GP C +L C PC ATC++ P
Sbjct: 767 STDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQ 826
Query: 865 GFVCVAEATFREG 877
G C+ + G
Sbjct: 827 GPRCLCPTGYTGG 839
Score = 60.1 bits (144), Expect = 1e-08
Identities = 33/93 (35%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 789 QPSELGGRQSWNLTAGCVSEDM--CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL 846
QPS T SE+M C PC NGG+C + ++CTCP + TGP C
Sbjct: 709 QPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTST 768
Query: 847 -WCPGQPCLPPATCEEVPDGFVCVAEATFREGP 878
+C PC TC P F C+ F +GP
Sbjct: 769 DYCVSAPCFNGGTCVNRPGTFSCLCAMGF-QGP 800
Score = 59.7 bits (143), Expect = 2e-08
Identities = 77/327 (23%), Positives = 104/327 (31%), Gaps = 42/327 (12%)
Query: 573 DATFAGCLQDVRVDGHLLLPEDLGENVLLGC--------ERREQCRPLPCVHGGSCVDLW 624
+A GC+ G P+ G N E C PC++GGSC
Sbjct: 689 EAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSP 748
Query: 625 THFRCDCARPHRGPTCADEIPAATFGLGGAPSSASFLLQELPGP-NLTVSFLLRTRESAG 683
+ C C H GP C +T AP PG + + + G
Sbjct: 749 GGYYCTCPPSHTGPQCQ----TSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEG 804
Query: 684 LLLQFANDSAAGLTVFLSEGRIRA---EVPGSPAVVLPGRWDDGLRHLVMLSFGPDQLQD 740
L DS R RA + P P + P + G +M
Sbjct: 805 KLRPSCADSPC---------RNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPR 855
Query: 741 LGQHVHVGGRLLAADSQPWGGPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELG----GR 796
+ G Q W GP L +L L C +D SS G
Sbjct: 856 NSHCLQTGPSFHCLCLQGWTGP----LCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSG 911
Query: 797 QSWNLTA-----GCVSEDM---CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-W 847
S+ G + +D C PC NG TC+ + + C C + G C+++L
Sbjct: 912 PSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDA 971
Query: 848 CPGQPCLPPATCEEVPDGFVCVAEATF 874
C QPC TC P GF C F
Sbjct: 972 CQSQPCHNHGTCTPKPGGFHCACPPGF 998
Score = 55.5 bits (132), Expect = 3e-07
Identities = 25/58 (43%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Query: 813 PDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFVCV 869
P PC +GG+CL T F+C CP +TG C A C QPC P +TC ++ F C+
Sbjct: 443 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCL 500
Score = 55.5 bits (132), Expect = 3e-07
Identities = 25/67 (37%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D C PC NGG C FHC C F GP C ++ C PC A+C ++P F
Sbjct: 553 DECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFF 612
Query: 868 CVAEATF 874
C+ + F
Sbjct: 613 CLCPSGF 619
Score = 55.1 bits (131), Expect = 4e-07
Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 6/78 (7%)
Query: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL----WCPGQPCLPPATCE 860
C D CS +PC NGG CL T+ C CP F G C + + PG PC +C
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPG-PCPKGTSCH 212
Query: 861 EVPDGFVCVAEATFREGP 878
F C+ +EGP
Sbjct: 213 NTLGSFQCLCPVG-QEGP 229
Score = 52.4 bits (124), Expect = 3e-06
Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 1/60 (1%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFVCV 869
C PC G TCL FHC CP G C + C PCL A C ++ +GF C+
Sbjct: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCI 538
Score = 49.7 bits (117), Expect = 2e-05
Identities = 81/293 (27%), Positives = 102/293 (34%), Gaps = 47/293 (16%)
Query: 611 PLPCVHGGSCVDLWT-HFRCDCARPHRGPTCADEIPAATFGL---GGAPSS---ASFLLQ 663
P PC +GG+C+ L C CA G TC P L GG+ + A L
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLP 91
Query: 664 ELPGPNLTVSFLLRTRES-AGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAV-VLPGRW 721
P P LT SFL G Q + + GR + G P +PG
Sbjct: 92 SSPSP-LTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWT 150
Query: 722 DDGLRHLVMLSFGPDQLQDLGQHVHVGGRLLAADSQ-----PWGGPFRGCLQDLRLDGCH 776
+ + S P GG LA Q P G C +D+ + C
Sbjct: 151 GEQCQLRDFCSANP---------CVNGGVCLATYPQIQCHCPPGFEGHACERDV--NECF 199
Query: 777 LPFFPLPLDNSSQPSELGGRQSW----------NLTAGCVSEDMCSPDPCFNGGTC-LVT 825
P P S + LG Q L AG C P C NGGTC L+
Sbjct: 200 QDPGPCPKGTSCH-NTLGSFQCLCPVGQEGPRCELRAG-----PCPPRGCSNGGTCQLMP 253
Query: 826 WND--FH-CTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFVCVAEATF 874
D FH C CP F GP C C C TC++ D + C+ T+
Sbjct: 254 EKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETW 306
Score = 47.0 bits (110), Expect = 1e-04
Identities = 24/74 (32%), Positives = 31/74 (41%), Gaps = 2/74 (2%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
V + C+ PC N C N F C C F+G C + + C PC C++ P
Sbjct: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571
Query: 865 GFVCVAEATFREGP 878
F C F EGP
Sbjct: 572 AFHCKCLPGF-EGP 584
Score = 47.0 bits (110), Expect = 1e-04
Identities = 25/66 (37%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Query: 805 CVSE-DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVP 863
C +E D C DPC G +CL F C CP+ FTG C L C C P C++
Sbjct: 586 CQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL-CAPNLCQPKQICKDQK 644
Query: 864 DGFVCV 869
D C+
Sbjct: 645 DKANCL 650
Score = 46.2 bits (108), Expect = 2e-04
Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 813 PDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
P C NGGTC + FHC C + + G +C + L C C P +TC + F C+
Sbjct: 323 PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCL 380
Score = 45.1 bits (105), Expect = 4e-04
Identities = 20/43 (46%), Positives = 23/43 (53%), Gaps = 3/43 (6%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWND---FHCTCPANFTGPTCAQQ 845
V D C PCF+GGTC T F C CP F GPTC+ +
Sbjct: 1045 VEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHR 1087
Score = 42.4 bits (98), Expect = 0.003
Identities = 22/65 (33%), Positives = 26/65 (40%)
Query: 799 WNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPAT 858
W T+ + D C C G TC+ F C CP TG C + C QPC A
Sbjct: 347 WGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQ 406
Query: 859 CEEVP 863
C P
Sbjct: 407 CSTNP 411
Score = 42.0 bits (97), Expect = 0.004
Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 4/68 (5%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQ---QLWCPGQP-CLPPATCEE 861
V+ D C C NGGTC + + C CP +TG C++ + G P C TC+
Sbjct: 275 VNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQN 334
Query: 862 VPDGFVCV 869
F CV
Sbjct: 335 SAGSFHCV 342
Score = 38.9 bits (89), Expect = 0.032
Identities = 36/122 (29%), Positives = 47/122 (38%), Gaps = 14/122 (11%)
Query: 781 PLPLDNSSQPSELGGRQSWNLTAGCVSEDM---CSP--DPCF-NGGTCLVTWNDFHCTCP 834
PL N QP ++ Q A C+ D C+P D C + G C + C C
Sbjct: 627 PLCAPNLCQPKQICKDQKDK--ANCLCPDGSPGCAPPEDNCTCHHGHCQRS----SCVCD 680
Query: 835 ANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGHNASSGRLL 893
+TGP C +L C PC TC P G+ C + GP + SG L
Sbjct: 681 VGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY-TGPTCSEEMTACHSGPCL 739
Query: 894 GG 895
G
Sbjct: 740 NG 741
Score = 38.5 bits (88), Expect = 0.042
Identities = 22/73 (30%), Positives = 26/73 (35%), Gaps = 8/73 (10%)
Query: 805 CVSEDMCSPDPCFNGGTCLVT--WNDFHCTCPANFTGPTCAQQL------WCPGQPCLPP 856
C EDMC PC C C C ++GPTC Q L PC
Sbjct: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHG 449
Query: 857 ATCEEVPDGFVCV 869
+C P F C+
Sbjct: 450 GSCLNTPGSFNCL 462
Score = 37.7 bits (86), Expect = 0.071
Identities = 16/57 (28%), Positives = 24/57 (42%)
Query: 603 CERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIPAATFGLGGAPSSAS 659
C+ R+ C PCV+GG C+ + +C C G C ++ G P S
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTS 210
Score = 37.0 bits (84), Expect = 0.12
Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 3/46 (6%)
Query: 607 EQCRPLPCVHGGSC---VDLWTHFRCDCARPHRGPTCADEIPAATF 649
+ C PC HGG+C F C C + GPTC+ P+ F
Sbjct: 1048 DPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGF 1093
Score = 36.2 bits (82), Expect = 0.21
Identities = 29/113 (25%), Positives = 36/113 (31%), Gaps = 16/113 (14%)
Query: 781 PLPLDNSSQPSELGGRQSWNLTAGCVSE-------DMCSPDPCFNGGTCLVTWNDF-HCT 832
P PL S PS L G E D C P C G C + + C+
Sbjct: 85 PAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCS 144
Query: 833 CPANFTGPTCAQQLWCPGQPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGH 885
C +TG C + +C PC+ C C P F GH
Sbjct: 145 CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHC--------PPGFEGH 189
Score = 35.8 bits (81), Expect = 0.27
Identities = 33/117 (28%), Positives = 42/117 (35%), Gaps = 25/117 (21%)
Query: 766 CLQDLRLDGCHLPFFPLPLDNSSQPSELG-GRQSWNLTAGCVSEDMCSPDPCF------N 818
C+ +R G FP P N L G+ + G + E PDPC N
Sbjct: 17 CVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQN 76
Query: 819 GGTCLV--------------TWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEE 861
GG+C F CTC FTG C +L PC PP+ C +
Sbjct: 77 GGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKL---EDPC-PPSFCSK 129
Score = 33.5 bits (75), Expect = 1.3
Identities = 13/30 (43%), Positives = 16/30 (53%)
Query: 611 PLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
P PC HGGSC++ F C C + G C
Sbjct: 443 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRC 472
Score = 31.2 bits (69), Expect = 6.7
Identities = 13/34 (38%), Positives = 16/34 (47%), Gaps = 4/34 (11%)
Query: 813 PDPCFNGGTCLVTWN----DFHCTCPANFTGPTC 842
P PC G+C T F C+CP + GP C
Sbjct: 1137 PSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRC 1170
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 308 bits (790), Expect = 2e-83
Identities = 160/477 (33%), Positives = 212/477 (44%), Gaps = 86/477 (18%)
Query: 38 PPSACASDPCAPGTECQA-TESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYC 96
P C C +C T GG C + PC +G C+ PD +RC C
Sbjct: 278 PYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQ--YRCTC 335
Query: 97 VPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCL 156
G+ G CE C S PC +G +C + +ECHCP G++G TC +++DECAS PC
Sbjct: 336 PDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCA 395
Query: 157 HGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQP------------------------ 192
GG+C+D V F C+C + G CQLD +EC+ +P
Sbjct: 396 AGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKG 455
Query: 193 -------------CAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCL 239
C HGGTC DLVNG++C C G+ G HCE E ECAS+PC C
Sbjct: 456 INCHINVNDCRGQCQHGGTCKDLVNGYQCVCP-RGFGGRHCELERDECASSPCHSGGLCE 514
Query: 240 EGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSD------PALYGGVQAAFP 293
+ F C C G+SG LCEVD D C SPC++G RC P +GG + P
Sbjct: 515 DLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVP 574
Query: 294 -----------------------------------GAFSFRHAAGFLCHCPPGFEGADCG 318
G + F C C GF G C
Sbjct: 575 REPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCH 634
Query: 319 VEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVA 378
+D+C +PC NGG C D + F+C CP G+ G C+ + ++CL DPC G C D V
Sbjct: 635 ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVN 694
Query: 379 GYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
+ C C + W G+ C + C +TC TC ++SG ++ C CPPG G C
Sbjct: 695 DFYCACDDGWKGKTCHSREFQCDAYTCSNGGTC---YDSG-DTFRCACPPGWKGSTC 747
Score = 304 bits (779), Expect = 3e-82
Identities = 161/484 (33%), Positives = 215/484 (44%), Gaps = 99/484 (20%)
Query: 46 PCAPGTECQATESGGYTCGPME----------PRGCATQPCHHGALCVPQGPDPTGFRCY 95
PC G C E Y C + C + PC +G C P+GF C+
Sbjct: 316 PCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEV---PSGFECH 372
Query: 96 CVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPC 155
C G+ GP C LDIDECAS PC G TC + D +EC CP + G TC+++ +EC PC
Sbjct: 373 CPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPC 432
Query: 156 LHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGY 215
L+ SC + +G + C C PG+ G C +++++C+ Q C HGGTC DLVNG++C C G+
Sbjct: 433 LNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQ-CQHGGTCKDLVNGYQCVCP-RGF 490
Query: 216 EGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGR 275
G HCE E ECAS+PC C + F C C G+SG LCEVD D C SPC++G R
Sbjct: 491 GGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGAR 550
Query: 276 CLQRSD------PALYGGVQAAFP-----------------------------------G 294
C P +GG + P G
Sbjct: 551 CYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHG 610
Query: 295 AFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPT 354
+ F C C GF G C +D+C +PC NGG C D + F+C CP G+ G
Sbjct: 611 RCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGEL 670
Query: 355 CEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPI 414
C+ + ++CL DPC G C D V + C C + W G+ C + C +TC TC
Sbjct: 671 CDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTC--- 727
Query: 415 FESGVHSYVCHCPPGTHGPF---------------------------------------C 435
++SG ++ C CPPG G C
Sbjct: 728 YDSG-DTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTC 786
Query: 436 GQNT 439
NT
Sbjct: 787 THNT 790
Score = 301 bits (772), Expect = 2e-81
Identities = 195/609 (32%), Positives = 261/609 (42%), Gaps = 99/609 (16%)
Query: 71 CATQP-CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASR-PCHHGATCRNLA- 127
C P C HG+ P ++C C + G C+ D++ C S PC +G TC N
Sbjct: 276 CVPYPGCVHGSCVEP-------WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEP 328
Query: 128 DRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDE 187
D+Y C CP GY+G CE C S PC +GGSC + F C C G+ G C LD+DE
Sbjct: 329 DQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDE 388
Query: 188 CQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRC 247
C S PCA GGTC D V+GF C C + G C+ + EC PC + SC +G + C
Sbjct: 389 CASNPCAAGGTCVDQVDGFECICPEQ-WVGATCQLDANECEGKPCLNAFSCKNLIGGYYC 447
Query: 248 LCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCH 307
C PG+ G C ++ ++C CQHGG C + G+ C
Sbjct: 448 DCIPGWKGINCHINVNDCRGQ-CQHGGTCKDLVN---------------------GYQCV 485
Query: 308 CPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPC 367
CP GF G C +E DECAS PC +GG C+DL +GF CHCP G++GP CE DVD C PC
Sbjct: 486 CPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPC 545
Query: 368 LHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATC-------IP-IFESGV 419
+G C + Y C CP+ +GG++CSV C G C + C +P SGV
Sbjct: 546 RNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGV 605
Query: 420 ------------HSYVCHCPPGTHGPFCGQNTTFSVMAGSPIQASVPAGGPLGLALRFRT 467
++ C C G G +C +N + G P + G + FR
Sbjct: 606 CGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCL--GQPCRNG---GTCIDEVDAFRC 660
Query: 468 TLPAGTLATRNDTKESLELALVAATLQATLWSYSTTVLVLRLPDLALNDGHWHQVEVVLH 527
P+G DT + LPD + G + + +
Sbjct: 661 FCPSGWEGELCDTNPND-----------------------CLPDPCHSRGRCYDLVNDFY 697
Query: 528 LA--------TLELRLWHEGCPARLCVASGPVALASTASATPLPAGISSAQLGDATFAGC 579
A T R + C A C G + P G + A + C
Sbjct: 698 CACDDGWKGKTCHSREFQ--CDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSC 755
Query: 580 LQDVRVDGHLLLPEDLGENVLL--GCERR------EQCRPLPCVHGGSCVDLWTHFRCDC 631
L + V+G + + + G E R C PLPC +GG CVD FRC+C
Sbjct: 756 LPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCEC 815
Query: 632 ARPHRGPTC 640
A GP C
Sbjct: 816 APGFAGPDC 824
Score = 280 bits (715), Expect = 8e-75
Identities = 151/467 (32%), Positives = 201/467 (43%), Gaps = 104/467 (22%)
Query: 42 CASDPCAPGTECQATESGGYTCG----------PMEPRGCATQPCHHGALCVPQGPDPTG 91
C PC C+ GGY C + C Q C HG C G
Sbjct: 427 CEGKPCLNAFSCKNL-IGGYYCDCIPGWKGINCHINVNDCRGQ-CQHGGTCKDL---VNG 481
Query: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
++C C GF G CEL+ DECAS PCH G C +LAD + CHCP G++G CE++VD C
Sbjct: 482 YQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCE 541
Query: 152 SAPCLHG--------------------------------GSC--LDGVGS---------- 167
+PC +G G+C +DG GS
Sbjct: 542 PSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTA 601
Query: 168 ------------------FRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCD 209
F C+C G+ GT C ++D+C QPC +GGTC D V+ FRC
Sbjct: 602 ASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCF 661
Query: 210 CAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSP 269
C +G+EG C+ +C PC C + + F C C G+ G+ C E +C +
Sbjct: 662 CP-SGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYT 720
Query: 270 CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDE-CASRP 328
C +GG C D F C CPPG++G+ C V + C P
Sbjct: 721 CSNGGTCYDSGDT---------------------FRCACPPGWKGSTCAVAKNSSCLPNP 759
Query: 329 CLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETW 388
C+NGG C F C C DG+ G TC + ++C PC +GG C D V + C C +
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGF 819
Query: 389 GGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
G DC + + CQ C ATC+ ++ Y C CPPG GP C
Sbjct: 820 AGPDCRINIDECQSSPCAYGATCV----DEINGYRCSCPPGRAGPRC 862
Score = 232 bits (592), Expect = 2e-60
Identities = 131/386 (33%), Positives = 177/386 (45%), Gaps = 48/386 (12%)
Query: 45 DPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTG-FRCYCVPGFQGP 103
+PC PG C+ + G GP P A+ C CV Q P G F C C GF G
Sbjct: 576 EPC-PGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQ---PGGNFSCICDSGFTGT 631
Query: 104 RCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLD 163
C +ID+C +PC +G TC + D + C CP G+ G C+ ++C PC G C D
Sbjct: 632 YCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYD 691
Query: 164 GVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCE-R 222
V F C C G+ G C +C + C++GGTC+D + FRC C G++G+ C
Sbjct: 692 LVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACP-PGWKGSTCAVA 750
Query: 223 EVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDP 282
+ C PC + +C+ SF C+C G+ G C + ++C PC +GG C+
Sbjct: 751 KNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVD---- 806
Query: 283 ALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGF 342
GV F C C PGF G DC + +DEC S PC G C D NG+
Sbjct: 807 ----GVN-------------WFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGY 849
Query: 343 QCHCPDGYAGPTCEEDVD---ECLS--DPCLHGGTCSDTVAGYICRCPETWGGRDCSVQL 397
+C CP G AGP C+E + C S P HG + + CRC + G RDCS
Sbjct: 850 RCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNS--CRCLD--GRRDCSKVW 905
Query: 398 TGCQ-----------GHTCPLAATCI 412
G + CPL C+
Sbjct: 906 CGWKPCLLAGQPEALSAQCPLGQRCL 931
Score = 170 bits (431), Expect = 7e-42
Identities = 116/341 (34%), Positives = 151/341 (44%), Gaps = 60/341 (17%)
Query: 39 PSACASDPCAPGTECQ--------ATESG--GYTCGPMEPRGCATQPCHHGALCVPQGPD 88
P+ C DPC C A + G G TC E + C C +G C G
Sbjct: 675 PNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQ-CDAYTCSNGGTCYDSGDT 733
Query: 89 PTGFRCYCVPGFQGPRCELDIDE-CASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEV 147
FRC C PG++G C + + C PC +G TC + C C G+ G TC
Sbjct: 734 ---FRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNT 790
Query: 148 DECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFR 207
++C PC +GG C+DGV FRC CAPG+ G C++++DECQS PCA+G TC D +NG+R
Sbjct: 791 NDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYR 850
Query: 208 CDCAGTGYEGTHCEREV---LECAS--APCEHNASCLEGLGSFRCL--------CWPGYS 254
C C G G C+ + C S P H +S +E S RCL W G+
Sbjct: 851 CSCP-PGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWK 909
Query: 255 GELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEG 314
L + E S+ C G RCL+++ PG C PP
Sbjct: 910 PCLL-AGQPEALSAQCPLGQRCLEKA------------PGQ----------CLRPPCEAW 946
Query: 315 ADCGVEVDECASRPCL-NGGH----CQDLPNGF-QCHCPDG 349
+CG E E S PCL GH C L F + H P G
Sbjct: 947 GECGAE--EPPSTPCLPRSGHLDNNCARLTLHFNRDHVPQG 985
Score = 107 bits (268), Expect = 6e-23
Identities = 63/182 (34%), Positives = 77/182 (42%), Gaps = 23/182 (12%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
CA SPC G C DL D F C C G+ GP CE VD C +PC G RC+ + +G + C
Sbjct: 502 CASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCY-NLEGDYYC 560
Query: 1119 RCPPGFGGPRC---RLPVPSKECSLNVTC-LDGSPCEGGSPAA----------------- 1157
CP FGG C R P P C + C D P G+ A+
Sbjct: 561 ACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNF 620
Query: 1158 NCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGLPLP 1217
+C C G G C C PC NGGTC C C + + G+ C+ LP
Sbjct: 621 SCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP 680
Query: 1218 LP 1219
P
Sbjct: 681 DP 682
Score = 106 bits (265), Expect = 1e-22
Identities = 51/151 (33%), Positives = 65/151 (43%), Gaps = 2/151 (1%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C P PC G C DL + F CAC GW+G C + C + C+ G F C
Sbjct: 678 CLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCA 737
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
CPPG+ G C V L C++G C G + +C C +G G+ C T C
Sbjct: 738 CPPGWKGSTC--AVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNP 795
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
PC NGG C C C F+G C +
Sbjct: 796 LPCYNGGICVDGVNWFRCECAPGFAGPDCRI 826
Score = 106 bits (264), Expect = 2e-22
Identities = 53/154 (34%), Positives = 73/154 (47%), Gaps = 6/154 (3%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTHPDGRFEC 1118
C +PC + G+C ++ F C C GW GP C +D C S PCA G C DG FEC
Sbjct: 351 CTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDG-FEC 409
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
CP + G C+L + EC CL+ C+ C C+ G G C + C
Sbjct: 410 ICPEQWVGATCQL--DANECE-GKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCR 466
Query: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCEVAK 1212
C +GGTC+ +C+C F G+ CE+ +
Sbjct: 467 GQ-CQHGGTCKDLVNGYQCVCPRGFGGRHCELER 499
Score = 100 bits (250), Expect = 7e-21
Identities = 55/149 (36%), Positives = 67/149 (44%), Gaps = 6/149 (4%)
Query: 1064 PCLHDGACRDLF-DAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFECRCP 1121
PC + G C + D + C C G+ G CE C S PCA G CH P G FEC CP
Sbjct: 316 PCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSG-FECHCP 374
Query: 1122 PGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANP 1181
G+ GP C L + EC+ N C G C C C E G CQ+ CE P
Sbjct: 375 SGWSGPTCALDI--DECASN-PCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKP 431
Query: 1182 CLNGGTCRAAGGVSECICNARFSGQFCEV 1210
CLN +C+ G C C + G C +
Sbjct: 432 CLNAFSCKNLIGGYYCDCIPGWKGINCHI 460
Score = 89.0 bits (219), Expect = 3e-17
Identities = 42/112 (37%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C P+PC++ G C +F+C C GWEG C + + C+ PC G F C
Sbjct: 755 CLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCE 814
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQ 1171
C PGF GP CR+ + EC + C G+ C CSC G AG RCQ
Sbjct: 815 CAPGFAGPDCRINI--DECQ-SSPCAYGATCVDEINGYRCSCPPGRAGPRCQ 863
Score = 84.0 bits (206), Expect = 9e-16
Identities = 57/221 (25%), Positives = 74/221 (33%), Gaps = 62/221 (28%)
Query: 1059 VCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCA-------------- 1104
+C PSPC + C +L + CAC + G C +PC C
Sbjct: 539 LCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMP 598
Query: 1105 ----------RGRCHTHPDGRFECRCPPGFGGPRCRLPVPS---KECSLNVTCLDG---- 1147
GRC + P G F C C GF G C + + C TC+D
Sbjct: 599 GTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAF 658
Query: 1148 ----------------------SPCEGGSPAAN------CSCLEGLAGQRCQVPTLPCEA 1179
PC + C+C +G G+ C C+A
Sbjct: 659 RCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDA 718
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEVAKG---LPLP 1217
C NGGTC +G C C + G C VAK LP P
Sbjct: 719 YTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNP 759
Score = 83.6 bits (205), Expect = 1e-15
Identities = 46/132 (34%), Positives = 60/132 (45%), Gaps = 14/132 (10%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C P PC + G C D + F C C PG+ GP C ++D C S+PCA G + C
Sbjct: 793 CNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCS 852
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLD-GSPCEGGS----PAANCSCLEGLAGQRCQVPT 1174
CPPG GPRC+ + +C G+P GS +C CL+G R
Sbjct: 853 CPPGRAGPRCQ-----EVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDG----RRDCSK 903
Query: 1175 LPCEANPCLNGG 1186
+ C PCL G
Sbjct: 904 VWCGWKPCLLAG 915
Score = 64.7 bits (156), Expect = 5e-10
Identities = 47/151 (31%), Positives = 64/151 (42%), Gaps = 24/151 (15%)
Query: 759 WGGPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSEL-----GGRQSWNLTAGCVSEDMCSP 813
WGG C +DL G H P +++P + G N +E C+
Sbjct: 299 WGGLL--CDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEK---AEHACTS 353
Query: 814 DPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCVA-- 870
+PC NGG+C + F C CP+ ++GPTCA + C PC TC + DGF C+
Sbjct: 354 NPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPE 413
Query: 871 ---------EATFREGPPA--AFSGHNASSG 890
+A EG P AFS N G
Sbjct: 414 QWVGATCQLDANECEGKPCLNAFSCKNLIGG 444
Score = 57.4 bits (137), Expect = 9e-08
Identities = 45/161 (27%), Positives = 62/161 (38%), Gaps = 42/161 (26%)
Query: 308 CPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEE---------- 357
C G+ G +C V C L G C +P +C C G+ G C+E
Sbjct: 231 CMDGWMGKECKEAV--CKQGCNLLHGGCT-VPG--ECRCSYGWQGRFCDECVPYPGCVHG 285
Query: 358 ---------------------DVDECLS-DPCLHGGTCSDTVAG-YICRCPETWGGRDCS 394
D++ C S PC +GGTC + Y C CP+ + GR+C
Sbjct: 286 SCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCE 345
Query: 395 VQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
C + C +C + SG + CHCP G GP C
Sbjct: 346 KAEHACTSNPCANGGSCHEV-PSG---FECHCPSGWSGPTC 382
Score = 55.8 bits (133), Expect = 3e-07
Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 796 RQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCL 854
R W + + C+P PC+NGG C+ N F C C F GP C + C PC
Sbjct: 778 RDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCA 837
Query: 855 PPATCEEVPDGFVC 868
ATC + +G+ C
Sbjct: 838 YGATCVDEINGYRC 851
Score = 54.3 bits (129), Expect = 7e-07
Identities = 28/87 (32%), Positives = 36/87 (41%), Gaps = 9/87 (10%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
+ D C+ PC +GG C + FHC CP F+GP C + C PC A C +
Sbjct: 497 LERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEG 556
Query: 865 GFVCVAEATFREGPPAAFSGHNASSGR 891
+ C P F G N S R
Sbjct: 557 DYYCAC--------PDDFGGKNCSVPR 575
Score = 53.1 bits (126), Expect = 2e-06
Identities = 47/151 (31%), Positives = 59/151 (39%), Gaps = 29/151 (19%)
Query: 1073 DLFDAFAC------ACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRF---ECRCPPG 1123
D F + C AC GW G C+ A C +G C+ G ECRC G
Sbjct: 216 DFFGHYTCDQYGNKACMDGWMGKECK-------EAVCKQG-CNLLHGGCTVPGECRCSYG 267
Query: 1124 FGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEAN-PC 1182
+ G C EC C+ GS E C+C G C C ++ PC
Sbjct: 268 WQGRFC------DECVPYPGCVHGSCVEPWQ----CNCETNWGGLLCDKDLNYCGSHHPC 317
Query: 1183 LNGGTC-RAAGGVSECICNARFSGQFCEVAK 1212
NGGTC A C C +SG+ CE A+
Sbjct: 318 TNGGTCINAEPDQYRCTCPDGYSGRNCEKAE 348
Score = 53.1 bits (126), Expect = 2e-06
Identities = 76/289 (26%), Positives = 95/289 (32%), Gaps = 55/289 (19%)
Query: 614 CVHGGSCVDLWTHFRCDCARPHRGPTCA---DEIPAATFGLGG-----APSSASFLLQEL 665
C HGG+C DL ++C C R G C DE ++ GG A Q
Sbjct: 469 CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGF 528
Query: 666 PGPNLTVSFLL----------RTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAV 715
GP V L R G D G + R PG
Sbjct: 529 SGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVP----REPCPGGACR 584
Query: 716 VLPGRWDDGLRHLVMLSFGPDQLQDLGQHVHVGGRLLAADSQPWGGPFRGCLQDLRLDG- 774
V+ G D + G G H GR + SQP GG F C+ D G
Sbjct: 585 VIDGCGSDAGPGMP----GTAASGVCGPH----GRCV---SQP-GGNF-SCICDSGFTGT 631
Query: 775 -CHLPFFPLPLDNSSQPSELGGR-------------QSWNLTAGCVSEDMCSPDPCFNGG 820
CH D QP GG W + + C PDPC + G
Sbjct: 632 YCHENID----DCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRG 687
Query: 821 TCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFVC 868
C NDF+C C + G TC +++ C C TC + D F C
Sbjct: 688 RCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC 736
Score = 48.9 bits (115), Expect = 3e-05
Identities = 27/83 (32%), Positives = 35/83 (42%), Gaps = 6/83 (7%)
Query: 808 EDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC--AQQLWCPGQPCLPPATCEEVPDG 865
E C C NGGTC + + F C CP + G TC A+ C PC+ TC
Sbjct: 713 EFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGAS 772
Query: 866 FVCVAEATFREGPPAAFSGHNAS 888
F C+ R+G HN +
Sbjct: 773 FSCIC----RDGWEGRTCTHNTN 791
Score = 45.8 bits (107), Expect = 3e-04
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFV 867
D C PC NGGTC+ + F C CP+ + G C C PC C ++ + F
Sbjct: 638 DDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFY 697
Query: 868 CVAE 871
C +
Sbjct: 698 CACD 701
Score = 45.8 bits (107), Expect = 3e-04
Identities = 22/68 (32%), Positives = 28/68 (41%), Gaps = 1/68 (1%)
Query: 802 TAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCE 860
T C P+PC NGGTC+ + F C C + G TC C PC C
Sbjct: 746 TCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICV 805
Query: 861 EVPDGFVC 868
+ + F C
Sbjct: 806 DGVNWFRC 813
Score = 42.4 bits (98), Expect = 0.003
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 603 CERREQ-CRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
CE+ E C PC +GGSC ++ + F C C GPTCA +I
Sbjct: 344 CEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI 386
Score = 40.8 bits (94), Expect = 0.008
Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 6/53 (11%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL------WCPGQP 852
++ D C PC G TC+ N + C+CP GP C + + W G P
Sbjct: 826 INIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTP 878
Score = 39.7 bits (91), Expect = 0.019
Identities = 14/38 (36%), Positives = 21/38 (55%)
Query: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
++C+ PC +G +CVD +RC C GP C + I
Sbjct: 829 DECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVI 866
Score = 39.3 bits (90), Expect = 0.025
Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 603 CE-RREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
CE R++C PC GG C DL F C C + GP C ++
Sbjct: 495 CELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDV 537
Score = 38.5 bits (88), Expect = 0.042
Identities = 18/40 (45%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 603 CERRE-QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCA 641
C RE QC C +GG+C D FRC C +G TCA
Sbjct: 709 CHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCA 748
Score = 38.1 bits (87), Expect = 0.055
Identities = 31/100 (31%), Positives = 39/100 (39%), Gaps = 24/100 (24%)
Query: 346 CPDGYAGPTCEEDVDECLSDPC--LHGGTCSDTVAGYICRCPETWGGRDCS--VQLTGCQ 401
C DG+ G C+E V C LHGG TV G CRC W GR C V GC
Sbjct: 231 CMDGWMGKECKEAV---CKQGCNLLHGGC---TVPGE-CRCSYGWQGRFCDECVPYPGCV 283
Query: 402 GHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTF 441
+C V + C+C G C ++ +
Sbjct: 284 HGSC-------------VEPWQCNCETNWGGLLCDKDLNY 310
Score = 37.0 bits (84), Expect = 0.12
Identities = 24/96 (25%), Positives = 29/96 (30%), Gaps = 38/96 (39%)
Query: 811 CSPDPCFN-------------------------------------GGTCLVTWNDFHCTC 833
C PC N GGTC N + C C
Sbjct: 427 CEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVC 486
Query: 834 PANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFVC 868
P F G C ++ C PC CE++ DGF C
Sbjct: 487 PRGFGGRHCELERDECASSPCHSGGLCEDLADGFHC 522
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 297 bits (761), Expect = 4e-80
Identities = 156/482 (32%), Positives = 216/482 (44%), Gaps = 92/482 (19%)
Query: 38 PPSACASDPCAPGTECQA-TESGGYTCGPMEPRGCAT-QPCHHGALCVPQGPDPTGFRCY 95
P C C +C T GG C + C T QPC +G C GPD ++C
Sbjct: 267 PHPGCVHGICNEPWQCLCETNWGGQLCDK-DLNYCGTHQPCLNGGTCSNTGPDK--YQCS 323
Query: 96 CVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPC 155
C G+ GP CE+ C S PCH+ +C+ + +EC C G+ G TC +D+C+ C
Sbjct: 324 CPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNC 383
Query: 156 LHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHG------------------- 196
HGG+C D V F+CVC P + G CQLD +EC+++PC +
Sbjct: 384 SHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWM 443
Query: 197 ------------------GTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASC 238
+C DLVNG+RC C GY G HCER++ ECAS PC + C
Sbjct: 444 GQNCDININDCLGQCQNDASCRDLVNGYRCICP-PGYAGDHCERDIDECASNPCLNGGHC 502
Query: 239 LEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSD------PALYGGVQAAF 292
+ F+CLC G+SG LC++D D C +PCQ+G +C R+ P Y G +
Sbjct: 503 QNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSH 562
Query: 293 ---------------------------------------PGAFSFRHAAGFLCHCPPGFE 313
G + F C C GF
Sbjct: 563 LKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFT 622
Query: 314 GADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTC 373
G C +++C S PC NGG C D N ++C C DG+ G CE ++++C +PC +GGTC
Sbjct: 623 GTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTC 682
Query: 374 SDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGP 433
D V + C C W G+ C + + C TC TC ++ G ++ C CP G G
Sbjct: 683 RDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTC---YDEG-DAFKCMCPGGWEGT 738
Query: 434 FC 435
C
Sbjct: 739 TC 740
Score = 281 bits (719), Expect = 3e-75
Identities = 144/451 (31%), Positives = 201/451 (44%), Gaps = 58/451 (12%)
Query: 41 ACASDPCAPGTECQATESG----------GYTCGPMEPRGCATQPCHHGALCVPQGPDPT 90
AC SDPC C+ T G G TC C+ C HG C
Sbjct: 339 ACLSDPCHNRGSCKETSLGFECECSPGWTGPTCST-NIDDCSPNNCSHGGTCQDL---VN 394
Query: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC 150
GF+C C P + G C+LD +EC ++PC + +C+NL Y C C G+ G C++ +++C
Sbjct: 395 GFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDC 454
Query: 151 ASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDC 210
C + SC D V +RC+C PGY G C+ D+DEC S PC +GG C + +N F+C C
Sbjct: 455 LGQ-CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLC 513
Query: 211 AGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPC 270
TG+ G C+ ++ C PC++ A C + C C Y G+ C +D C ++PC
Sbjct: 514 P-TGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPC 572
Query: 271 QHGGRCL------QRSDPALYGGVQAAFP-GAFSFRHAAGFLCHCPPGFEGADCGVEVDE 323
+ C + Y P G + F C C GF G C +++
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIND 632
Query: 324 CASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICR 383
C S PC NGG C D N ++C C DG+ G CE ++++C +PC +GGTC D V + C
Sbjct: 633 CESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCD 692
Query: 384 CPETWGGRDCSVQLTGCQGHTCPLAATCI------------------------------P 413
C W G+ C + + C TC TC P
Sbjct: 693 CKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNP 752
Query: 414 IFESGV-----HSYVCHCPPGTHGPFCGQNT 439
G S+ C C G GP C QNT
Sbjct: 753 CHNGGTCVVNGESFTCVCKEGWEGPICAQNT 783
Score = 265 bits (677), Expect = 2e-70
Identities = 131/394 (33%), Positives = 180/394 (45%), Gaps = 58/394 (14%)
Query: 71 CATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRY 130
CA+ PC +G C + F+C C GF G C+LDID C PC +GA C N A Y
Sbjct: 491 CASNPCLNGGHCQNE---INRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDY 547
Query: 131 ECHCPLGYAGVTCEMEVDECASAPCLHGGSCL---------DGV---------------- 165
C CP Y G C D C + PC SC +GV
Sbjct: 548 FCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607
Query: 166 ---GSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCER 222
G F C C G+ GT C ++++C+S PC +GGTC D VN ++C C+ G+EG +CE
Sbjct: 608 QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSD-GWEGAYCET 666
Query: 223 EVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDP 282
+ +C+ PC + +C + + F C C G+ G+ C + +C + C +GG C D
Sbjct: 667 NINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGD- 725
Query: 283 ALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDE-CASRPCLNGGHCQDLPNG 341
F C CP G+EG C + + C PC NGG C
Sbjct: 726 --------------------AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGES 765
Query: 342 FQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQ 401
F C C +G+ GP C ++ ++C PC + GTC D Y C C + G DC + + CQ
Sbjct: 766 FTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQ 825
Query: 402 GHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
C ATC+ ++ Y C CPPG G C
Sbjct: 826 SSPCAFGATCV----DEINGYRCVCPPGHSGAKC 855
Score = 260 bits (665), Expect = 5e-69
Identities = 135/435 (31%), Positives = 193/435 (44%), Gaps = 68/435 (15%)
Query: 42 CASDPCAPGTECQATESGGYT-CGP--------MEPRGCATQPCHHGALCVPQGPDPTGF 92
C + PC C+ + Y C P + C Q C + A C G+
Sbjct: 416 CEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQ-CQNDASCRDL---VNGY 471
Query: 93 RCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECAS 152
RC C PG+ G CE DIDECAS PC +G C+N +R++C CP G++G C++++D C
Sbjct: 472 RCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEP 531
Query: 153 APCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTC------HDLVNG- 205
PC +G C + + C C Y G C D C++ PC +C +D G
Sbjct: 532 NPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGV 591
Query: 206 ---------------------FRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGS 244
F CDC G+ GT+C + +C S PC + +C++G+ S
Sbjct: 592 RYISSNVCGPHGKCKSQSGGKFTCDC-NKGFTGTYCHENINDCESNPCRNGGTCIDGVNS 650
Query: 245 FRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGF 304
++C+C G+ G CE + ++C+ +PC +GG C + F
Sbjct: 651 YKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVND---------------------F 689
Query: 305 LCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE-EDVDECL 363
C C G++G C +C C NGG C D + F+C CP G+ G TC CL
Sbjct: 690 YCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCL 749
Query: 364 SDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYV 423
+PC +GGTC + C C E W G C+ C H C + TC+ G + Y
Sbjct: 750 PNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCV----DGDNWYR 805
Query: 424 CHCPPGTHGPFCGQN 438
C C PG GP C N
Sbjct: 806 CECAPGFAGPDCRIN 820
Score = 245 bits (626), Expect = 2e-64
Identities = 132/433 (30%), Positives = 187/433 (43%), Gaps = 113/433 (26%)
Query: 96 CVPGFQGPRCE-----------------------------LDIDECASRP-CHHG----- 120
C+ G+ GP C L D+C P C HG
Sbjct: 220 CMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEP 279
Query: 121 ------------------------------ATCRNLA-DRYECHCPLGYAGVTCEMEVDE 149
TC N D+Y+C CP GY+G CE+
Sbjct: 280 WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHA 339
Query: 150 CASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCD 209
C S PC + GSC + F C C+PG+ G C ++D+C C+HGGTC DLVNGF+C
Sbjct: 340 CLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCV 399
Query: 210 CAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSP 269
C + G C+ + EC + PC + SC + S+ C C PG+ G+ C+++ ++C
Sbjct: 400 CP-PQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQ- 457
Query: 270 CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPC 329
CQ+ C + G+ C CPPG+ G C ++DECAS PC
Sbjct: 458 CQNDASCRDLVN---------------------GYRCICPPGYAGDHCERDIDECASNPC 496
Query: 330 LNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWG 389
LNGGHCQ+ N FQC CP G++G C+ D+D C +PC +G C + + Y C+CPE +
Sbjct: 497 LNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE 556
Query: 390 GRDCSVQLTGCQGHTCPLAATCIPIFES---------------GVH---------SYVCH 425
G++CS C+ C + +C S G H + C
Sbjct: 557 GKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCD 616
Query: 426 CPPGTHGPFCGQN 438
C G G +C +N
Sbjct: 617 CNKGFTGTYCHEN 629
Score = 223 bits (568), Expect = 9e-58
Identities = 127/438 (28%), Positives = 186/438 (42%), Gaps = 91/438 (20%)
Query: 42 CASDPCAPGTECQATESGGYTCGPMEPRG---------CATQPCH--------------- 77
C +PC G +C S + P + G C T PC
Sbjct: 529 CEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTP 588
Query: 78 ------HGALCVPQGPDPTG----FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLA 127
+C P G + F C C GF G C +I++C S PC +G TC +
Sbjct: 589 EGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGV 648
Query: 128 DRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDE 187
+ Y+C C G+ G CE +++C+ PC +GG+C D V F C C G+ G C +
Sbjct: 649 NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ 708
Query: 188 CQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCE-REVLECASAPCEHNASCLEGLGSFR 246
C C +GGTC+D + F+C C G G+EGT C C PC + +C+ SF
Sbjct: 709 CDEATCNNGGTCYDEGDAFKCMCPG-GWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFT 767
Query: 247 CLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLC 306
C+C G+ G +C + ++C+ PC + G C+ + + C
Sbjct: 768 CVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDN---------------------WYRC 806
Query: 307 HCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDV------- 359
C PGF G DC + ++EC S PC G C D NG++C CP G++G C+E
Sbjct: 807 ECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITM 866
Query: 360 -----------DECLSDPCLHGGTCSDTVAGYICRCPETW-GGRDCSVQLTGCQGHT-CP 406
D+C + CL+G C + W G R C + +GH+ CP
Sbjct: 867 GSVIPDGAKWDDDCNTCQCLNGRIA----------CSKVWCGPRPCLLH----KGHSECP 912
Query: 407 LAATCIPIFESGVHSYVC 424
+CIPI + + C
Sbjct: 913 SGQSCIPILDDQCFVHPC 930
Score = 167 bits (422), Expect = 8e-41
Identities = 107/353 (30%), Positives = 152/353 (43%), Gaps = 50/353 (14%)
Query: 32 GTVPSEPPSACASDPCAPGTEC-------QATESGGYTCGPMEP--RGCATQPCHHGALC 82
GT E + C S+PC G C + S G+ E C+ PCH+G C
Sbjct: 623 GTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTC 682
Query: 83 VPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVT 142
D F C C G++G C +C C++G TC + D ++C CP G+ G T
Sbjct: 683 RDLVND---FYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTT 739
Query: 143 CEM-EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHD 201
C + C PC +GG+C+ SF CVC G+ G C + ++C PC + GTC D
Sbjct: 740 CNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVD 799
Query: 202 LVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVD 261
N +RC+CA G+ G C + EC S+PC A+C++ + +RC+C PG+SG C+
Sbjct: 800 GDNWYRCECA-PGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ-- 856
Query: 262 EDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEV 321
E + PC G + P + C C G
Sbjct: 857 --EVSGRPCITMG---------------SVIPDGAKWDDDCN-TCQCLNG----RIACSK 894
Query: 322 DECASRPC-LNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTC 373
C RPC L+ GH + P+G C P + D+C PC G C
Sbjct: 895 VWCGPRPCLLHKGH-SECPSGQSCI-------PILD---DQCFVHPCTGVGEC 936
Score = 151 bits (382), Expect = 3e-36
Identities = 85/279 (30%), Positives = 127/279 (45%), Gaps = 49/279 (17%)
Query: 42 CASDPCAPGTECQATESGGY----------TCGPMEPRGCATQPCHHGALCVPQGPDPTG 91
C+ +PC G C+ + Y TC + + C C++G C +G
Sbjct: 671 CSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-CDEATCNNGGTCYDEGD---A 726
Query: 92 FRCYCVPGFQGPRCELDIDE-CASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC 150
F+C C G++G C + + C PCH+G TC + + C C G+ G C ++C
Sbjct: 727 FKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDC 786
Query: 151 ASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDC 210
+ PC + G+C+DG +RC CAPG+ G C+++++ECQS PCA G TC D +NG+RC C
Sbjct: 787 SPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVC 846
Query: 211 AGTGYEGTHCEREVLECASAPCE----------------HNASCLEG--------LGSFR 246
G+ G C+ E + PC + CL G G
Sbjct: 847 P-PGHSGAKCQ----EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRP 901
Query: 247 CLCWPGY----SGELC-EVDEDECASSPCQHGGRCLQRS 280
CL G+ SG+ C + +D+C PC G C S
Sbjct: 902 CLLHKGHSECPSGQSCIPILDDQCFVHPCTGVGECRSSS 940
Score = 107 bits (268), Expect = 6e-23
Identities = 48/151 (31%), Positives = 71/151 (47%), Gaps = 4/151 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C+P+ C H G C+DL + F C C P W G C+ + C + PC + + + C
Sbjct: 378 CSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCD 437
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
C PG+ G C + + +C C + + C C C G AG C+ C +
Sbjct: 438 CLPGWMGQNCDINI--NDCL--GQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECAS 493
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
NPCLNGG C+ +C+C FSG C++
Sbjct: 494 NPCLNGGHCQNEINRFQCLCPTGFSGNLCQL 524
Score = 102 bits (254), Expect = 2e-21
Identities = 52/152 (34%), Positives = 68/152 (44%), Gaps = 4/152 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTHPDGRFEC 1118
C+ +PC + G CRDL + F C C GW+G C + C A C G C+ D F+C
Sbjct: 671 CSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDA-FKC 729
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
CP G+ G C + + C N C +G C + C C EG G C T C
Sbjct: 730 MCPGGWEGTTCNI-ARNSSCLPN-PCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCS 787
Query: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
+PC N GTC C C F+G C +
Sbjct: 788 PHPCYNSGTCVDGDNWYRCECAPGFAGPDCRI 819
Score = 99.0 bits (245), Expect = 3e-20
Identities = 49/150 (32%), Positives = 63/150 (42%), Gaps = 4/150 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C +PC + G C D +++ C C GWEG CE +++ C PC G F C
Sbjct: 633 CESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCD 692
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVP-TLPCE 1178
C G+ G C +C TC +G C A C C G G C + C
Sbjct: 693 CKNGWKGKTCH--SRDSQCD-EATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCL 749
Query: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
NPC NGGTC G C+C + G C
Sbjct: 750 PNPCHNGGTCVVNGESFTCVCKEGWEGPIC 779
Score = 97.1 bits (240), Expect = 1e-19
Identities = 55/172 (31%), Positives = 75/172 (43%), Gaps = 31/172 (18%)
Query: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
C +D +CRDL + + C C PG+ G CE +D C S PC G + RF+C CP GF
Sbjct: 458 CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF 517
Query: 1125 GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRC-----QVPTLPCE- 1178
G C+L + C N C +G+ C + C C E G+ C T PCE
Sbjct: 518 SGNLCQLDI--DYCEPN-PCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEV 574
Query: 1179 ---------------------ANPCLNGGTCRA-AGGVSECICNARFSGQFC 1208
+N C G C++ +GG C CN F+G +C
Sbjct: 575 IDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYC 626
Score = 92.4 bits (228), Expect = 2e-18
Identities = 53/177 (29%), Positives = 73/177 (41%), Gaps = 29/177 (16%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
CA +PCL+ G C++ + F C C G+ G C+ +D C PC G +C+ F C
Sbjct: 491 CASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYF-C 549
Query: 1119 RCPPGFGGPRCR-------------------------LPVPSKECSLNVTCLDGSPCEGG 1153
+CP + G C P + S NV C C+
Sbjct: 550 KCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNV-CGPHGKCKSQ 608
Query: 1154 SPAA-NCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
S C C +G G C CE+NPC NGGTC +CIC+ + G +CE
Sbjct: 609 SGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCE 665
Score = 89.7 bits (221), Expect = 2e-17
Identities = 50/157 (31%), Positives = 67/157 (42%), Gaps = 10/157 (6%)
Query: 1044 WPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPC 1103
W GT I R + C P+PC + G C ++F C C GWEGP C + + C PC
Sbjct: 735 WEGTTCNI--ARNSS-CLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPC 791
Query: 1104 ARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLE 1163
D + C C PGF GP CR+ + EC + C G+ C C C
Sbjct: 792 YNSGTCVDGDNWYRCECAPGFAGPDCRINI--NECQ-SSPCAFGATCVDEINGYRCVCPP 848
Query: 1164 GLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICN 1200
G +G +CQ PC+ G+ G + CN
Sbjct: 849 GHSGAKCQ----EVSGRPCITMGSVIPDGAKWDDDCN 881
Score = 87.0 bits (214), Expect = 1e-16
Identities = 46/155 (29%), Positives = 74/155 (47%), Gaps = 12/155 (7%)
Query: 1060 CAPSP-CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHS-APCARGRC--HTHPDGR 1115
C P P C+H G C + + C C W G C+ ++ C + PC G +T PD +
Sbjct: 265 CIPHPGCVH-GICNE---PWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPD-K 319
Query: 1116 FECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTL 1175
++C CP G+ GP C + ++ L+ C + C+ S C C G G C
Sbjct: 320 YQCSCPEGYSGPNCEI---AEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNID 376
Query: 1176 PCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
C N C +GGTC+ +C+C +++G+ C++
Sbjct: 377 DCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQL 411
Score = 83.2 bits (204), Expect = 1e-15
Identities = 54/224 (24%), Positives = 74/224 (33%), Gaps = 66/224 (29%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCA--------------- 1104
C P+PC + C + + C C +EG C D C + PC
Sbjct: 529 CEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTP 588
Query: 1105 -------------RGRCHTHPDGRFECRCPPGFGGPRCRLPV---PSKECSLNVTCLDG- 1147
G+C + G+F C C GF G C + S C TC+DG
Sbjct: 589 EGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGV 648
Query: 1148 -------------------------SPCEGGSPAAN------CSCLEGLAGQRCQVPTLP 1176
+PC G + C C G G+ C
Sbjct: 649 NSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ 708
Query: 1177 CEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKG---LPLP 1217
C+ C NGGTC G +C+C + G C +A+ LP P
Sbjct: 709 CDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNP 752
Score = 76.3 bits (186), Expect = 2e-13
Identities = 51/175 (29%), Positives = 73/175 (41%), Gaps = 21/175 (12%)
Query: 1036 GAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHV 1095
G + W G CR C+P G+C+ D C C GW+G C
Sbjct: 216 GNKTCMEGWMGPECNRAICRQG--CSPK----HGSCKLPGD---CRCQYGWQGLYC---- 262
Query: 1096 DPCHSAP-CARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGS 1154
D C P C G C+ ++C C +GG C + C + CL+G C
Sbjct: 263 DKCIPHPGCVHGICNEP----WQCLCETNWGGQLCDKDL--NYCGTHQPCLNGGTCSNTG 316
Query: 1155 PAA-NCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
P CSC EG +G C++ C ++PC N G+C+ EC C+ ++G C
Sbjct: 317 PDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTC 371
Score = 60.8 bits (146), Expect = 8e-09
Identities = 46/150 (30%), Positives = 60/150 (40%), Gaps = 27/150 (18%)
Query: 1073 DLFDAFAC------ACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRF--ECRCPPGF 1124
D F +AC C GW GP C + A C +G H + +CRC G+
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGPEC-------NRAICRQGCSPKHGSCKLPGDCRCQYGW 257
Query: 1125 GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEAN-PCL 1183
G C +P C V + P + C C GQ C C + PCL
Sbjct: 258 QGLYCDKCIPHPGC---VHGICNEPWQ-------CLCETNWGGQLCDKDLNYCGTHQPCL 307
Query: 1184 NGGTCRAAGGVS-ECICNARFSGQFCEVAK 1212
NGGTC G +C C +SG CE+A+
Sbjct: 308 NGGTCSNTGPDKYQCSCPEGYSGPNCEIAE 337
Score = 59.7 bits (143), Expect = 2e-08
Identities = 35/114 (30%), Positives = 53/114 (46%), Gaps = 5/114 (4%)
Query: 759 WGGPFRGCLQDLRLDGCHLPFFPLPLDNSSQPS--ELGGRQSWNLTAGCVSEDMCSPDPC 816
WGG C +DL G H P +++ P + + ++ ++E C DPC
Sbjct: 288 WGGQL--CDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPC 345
Query: 817 FNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
N G+C T F C C +TGPTC+ + C C TC+++ +GF CV
Sbjct: 346 HNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCV 399
Score = 57.8 bits (138), Expect = 7e-08
Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 796 RQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCL 854
++ W + + CSP PC+N GTC+ N + C C F GP C + C PC
Sbjct: 771 KEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCA 830
Query: 855 PPATCEEVPDGFVCV 869
ATC + +G+ CV
Sbjct: 831 FGATCVDEINGYRCV 845
Score = 57.0 bits (136), Expect = 1e-07
Identities = 25/68 (36%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Query: 802 TAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCE 860
T C P+PC NGGTC+V F C C + GP CAQ C PC TC
Sbjct: 739 TCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCV 798
Query: 861 EVPDGFVC 868
+ + + C
Sbjct: 799 DGDNWYRC 806
Score = 53.5 bits (127), Expect = 1e-06
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D CSP+ C +GGTC N F C CP +TG TC C +PC+ +C+ + +
Sbjct: 376 DDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYY 435
Query: 868 C 868
C
Sbjct: 436 C 436
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/60 (40%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFVCV 869
CS +PC NGGTC NDF+C C + G TC ++ C C TC + D F C+
Sbjct: 671 CSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCM 730
Score = 51.2 bits (121), Expect = 6e-06
Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 9/81 (11%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D C+ +PC NGG C N F C CP F+G C + +C PC A C +
Sbjct: 489 DECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYF 548
Query: 868 CVAEATFREGPPAAFSGHNAS 888
C P + G N S
Sbjct: 549 CKC--------PEDYEGKNCS 561
Score = 51.2 bits (121), Expect = 6e-06
Identities = 31/87 (35%), Positives = 40/87 (45%), Gaps = 4/87 (4%)
Query: 805 CVSED-MCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC--AQQLWCPGQPCLPPATCEE 861
C S D C C NGGTC + F C CP + G TC A+ C PC TC
Sbjct: 702 CHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVV 761
Query: 862 VPDGFVCVAEATFREGPPAAFSGHNAS 888
+ F CV + + EGP A + ++ S
Sbjct: 762 NGESFTCVCKEGW-EGPICAQNTNDCS 787
Score = 47.0 bits (110), Expect = 1e-04
Identities = 20/59 (33%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVC 868
C +PC NGGTC+ N + C C + G C + C PC TC ++ + F C
Sbjct: 633 CESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYC 691
Score = 44.3 bits (103), Expect = 8e-04
Identities = 57/269 (21%), Positives = 88/269 (32%), Gaps = 30/269 (11%)
Query: 604 ERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIPAATFGLGGAPSSASFLLQ 663
E C PC +GG+C+D ++C C+ G C I + + L+
Sbjct: 628 ENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVN 687
Query: 664 ELPGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPGRWDD 723
+ F + + DS + G E + PG W+
Sbjct: 688 D---------FYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMC-PGGWEG 737
Query: 724 GLRHLVMLSFG-PDQLQDLGQHVHVGGRLLAADSQPWGGPFRGCLQDLRLDGCHLPFFPL 782
++ S P+ + G V G + W GP C Q+ + C P
Sbjct: 738 TTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPI--CAQNT--NDCS----PH 789
Query: 783 PLDNSSQPSELGGRQSWNLTAGCVSEDM------CSPDPCFNGGTCLVTWNDFHCTCPAN 836
P NS + G D C PC G TC+ N + C CP
Sbjct: 790 PCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPG 849
Query: 837 FTGPTCAQQLWCPGQPCLPPATCEEVPDG 865
+G C + G+PC+ + +PDG
Sbjct: 850 HSGAKCQE---VSGRPCITMGSV--IPDG 873
Score = 39.7 bits (91), Expect = 0.019
Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 9/71 (12%)
Query: 816 CFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCVAEATF 874
C N +C N + C CP + G C + + C PCL C+ + F C+
Sbjct: 458 CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLC---- 513
Query: 875 REGPPAAFSGH 885
P FSG+
Sbjct: 514 ----PTGFSGN 520
Score = 38.5 bits (88), Expect = 0.042
Identities = 17/39 (43%), Positives = 20/39 (51%), Gaps = 1/39 (2%)
Query: 603 CERR-EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
CE C PC +GG+C DL F CDC +G TC
Sbjct: 664 CETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTC 702
Score = 38.1 bits (87), Expect = 0.055
Identities = 15/34 (44%), Positives = 18/34 (52%)
Query: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
+ C P C HGG+C DL F+C C G TC
Sbjct: 376 DDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTC 409
Score = 38.1 bits (87), Expect = 0.055
Identities = 17/45 (37%), Positives = 19/45 (42%)
Query: 597 ENVLLGCERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCA 641
E R C P PC +GG+CV F C C GP CA
Sbjct: 736 EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICA 780
Score = 35.8 bits (81), Expect = 0.27
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
C PC N +C ++C C + G C + C GQ C A+C ++ +G+ C+
Sbjct: 416 CEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQ-CQNDASCRDLVNGYRCI 474
Score = 35.4 bits (80), Expect = 0.35
Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 603 CERREQ-CRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
CE E C PC + GSC + F C+C+ GPTC+ I
Sbjct: 333 CEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNI 375
Score = 32.3 bits (72), Expect = 3.0
Identities = 15/43 (34%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 603 CERR-EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
CER ++C PC++GG C + F+C C G C +I
Sbjct: 484 CERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDI 526
Score = 32.3 bits (72), Expect = 3.0
Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 5/65 (7%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
+S ++C P +G + F C C FTG C + + C PC TC + +
Sbjct: 594 ISSNVCGP----HGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVN 649
Query: 865 GFVCV 869
+ C+
Sbjct: 650 SYKCI 654
Score = 32.0 bits (71), Expect = 3.9
Identities = 10/35 (28%), Positives = 17/35 (48%)
Query: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCA 641
+ C P PC +G C + + + C C + G C+
Sbjct: 527 DYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCS 561
Score = 31.6 bits (70), Expect = 5.1
Identities = 12/33 (36%), Positives = 16/33 (48%)
Query: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
+C PCV+ SC +L + CDC G C
Sbjct: 415 ECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNC 447
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 289 bits (739), Expect = 1e-77
Identities = 152/484 (31%), Positives = 210/484 (43%), Gaps = 98/484 (20%)
Query: 41 ACASDPCAPGTECQATESG----------GYTCGPMEPRGCATQPCHHGALCVPQGPDPT 90
AC S+PCA G C SG G TC ++ CA+ PC G CV Q
Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCA-LDIDECASNPCAAGGTCVDQ---VD 405
Query: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC 150
GF C C + G C+LD+++C + C HG TC++L + Y+C CP G+ G CE+E DEC
Sbjct: 406 GFECICPEQWVGATCQLDVNDCRGQ-CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDEC 464
Query: 151 ASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDC 210
AS+PC GG C D F C C G+ G C++D+D C+ PC +G C++L + C C
Sbjct: 465 ASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCAC 524
Query: 211 ------------------------------AGTGYEG----------------------- 217
AG G G
Sbjct: 525 PDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSC 584
Query: 218 --------THCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSP 269
T+C + +C PC + +C++ + +FRC C G+ GELC+ + ++C P
Sbjct: 585 ICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDP 644
Query: 270 CQHGGRCLQ-------RSDPALYG----------GVQAAFPGAFSFRHAAGFLCHCPPGF 312
C GRC D G G + F C CPPG+
Sbjct: 645 CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGW 704
Query: 313 EGADCGV-EVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGG 371
+G+ C V + C PC+NGG C F C C DG+ G TC + ++C PC +GG
Sbjct: 705 KGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGG 764
Query: 372 TCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTH 431
C D V + C C + G DC + + CQ C ATC+ ++ Y C CPPG
Sbjct: 765 ICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCV----DEINGYRCSCPPGRA 820
Query: 432 GPFC 435
GP C
Sbjct: 821 GPRC 824
Score = 280 bits (717), Expect = 5e-75
Identities = 190/628 (30%), Positives = 267/628 (42%), Gaps = 106/628 (16%)
Query: 59 GGYTCGPMEPRGC-------------ATQPCH--HGALCVPQGPDPTGFRCYCVPGFQGP 103
G YTC + C Q C+ HG VP C C G+QG
Sbjct: 219 GHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPG-------ECRCSYGWQGR 271
Query: 104 RCELDIDECASRP-CHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASA-PCLHGGSC 161
C DEC P C HG+ + ++C+C + G+ C+ +++ C S PC +GG+C
Sbjct: 272 FC----DECVPYPGCVHGSC----VEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTC 323
Query: 162 LDGV-GSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHC 220
++ +RC C GY G C+ C S PCA+GG+CH++ +GF C C +G+ G C
Sbjct: 324 INAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCP-SGWSGPTC 382
Query: 221 EREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRS 280
++ ECAS PC +C++ + F C+C + G C++D ++C CQHGG C
Sbjct: 383 ALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQ-CQHGGTCKDLV 441
Query: 281 DPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPN 340
+ G+ C CP GF G C +E DECAS PC +GG C+DL +
Sbjct: 442 N---------------------GYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLAD 480
Query: 341 GFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGC 400
GF CHCP G++GP CE DVD C PC +G C + Y C CP+ +GG++CSV C
Sbjct: 481 GFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPC 540
Query: 401 QGHTCPLAATC-------IP-IFESGV------------HSYVCHCPPGTHGPFCGQNTT 440
G C + C +P SGV ++ C C G G +C +N
Sbjct: 541 PGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHEN-- 598
Query: 441 FSVMAGSPIQASVPAGGPLGLALRFRTTLPAGTLATRNDTKESLELALVAATLQATLWSY 500
G P + G + FR P+G DT + L S
Sbjct: 599 IDDCLGQPCR---NGGTCIDEVDAFRCFCPSGWEGELCDTNPN-------DCLPDPCHSR 648
Query: 501 STTVLVLRLPDLALNDGHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALASTASAT 560
++ A +DG W T R + C A C G +
Sbjct: 649 GRCYDLVNDFYCACDDG-WKG-------KTCHSREFQ--CDAYTCSNGGTCYDSGDTFRC 698
Query: 561 PLPAGISSAQLGDATFAGCLQDVRVDGHLLLPEDLGENVLL--GCERR------EQCRPL 612
P G + A + CL + V+G + + + G E R C PL
Sbjct: 699 ACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPL 758
Query: 613 PCVHGGSCVDLWTHFRCDCARPHRGPTC 640
PC +GG CVD FRC+CA GP C
Sbjct: 759 PCYNGGICVDGVNWFRCECAPGFAGPDC 786
Score = 232 bits (592), Expect = 2e-60
Identities = 131/386 (33%), Positives = 177/386 (45%), Gaps = 48/386 (12%)
Query: 45 DPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTG-FRCYCVPGFQGP 103
+PC PG C+ + G GP P A+ C CV Q P G F C C GF G
Sbjct: 538 EPC-PGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQ---PGGNFSCICDSGFTGT 593
Query: 104 RCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLD 163
C +ID+C +PC +G TC + D + C CP G+ G C+ ++C PC G C D
Sbjct: 594 YCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYD 653
Query: 164 GVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCE-R 222
V F C C G+ G C +C + C++GGTC+D + FRC C G++G+ C
Sbjct: 654 LVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACP-PGWKGSTCAVA 712
Query: 223 EVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDP 282
+ C PC + +C+ SF C+C G+ G C + ++C PC +GG C+
Sbjct: 713 KNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVD---- 768
Query: 283 ALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGF 342
GV F C C PGF G DC + +DEC S PC G C D NG+
Sbjct: 769 ----GVN-------------WFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGY 811
Query: 343 QCHCPDGYAGPTCEEDVD---ECLS--DPCLHGGTCSDTVAGYICRCPETWGGRDCSVQL 397
+C CP G AGP C+E + C S P HG + + CRC + G RDCS
Sbjct: 812 RCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNS--CRCLD--GRRDCSKVW 867
Query: 398 TGCQ-----------GHTCPLAATCI 412
G + CPL C+
Sbjct: 868 CGWKPCLLAGQPEALSAQCPLGQRCL 893
Score = 196 bits (498), Expect = 1e-49
Identities = 125/421 (29%), Positives = 176/421 (41%), Gaps = 61/421 (14%)
Query: 39 PSACASDPCAPGTECQATESGGYTC----------GPMEPRGCATQPCHHGALCVPQGPD 88
P AS C P C + G ++C C QPC +G C+ +
Sbjct: 560 PGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCI---DE 616
Query: 89 PTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVD 148
FRC+C G++G C+ + ++C PCH C +L + + C C G+ G TC
Sbjct: 617 VDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREF 676
Query: 149 ECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLD-ECQSQPCAHGGTCHDLVNGFR 207
+C + C +GG+C D +FRC C PG+ G+ C + + C PC +GGTC F
Sbjct: 677 QCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFS 736
Query: 208 CDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECAS 267
C C G+EG C +C PC + C++G+ FRC C PG++G C ++ DEC S
Sbjct: 737 CICR-DGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQS 795
Query: 268 SPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVD---EC 324
SPC +G C+ + G+ C CPPG G C + C
Sbjct: 796 SPCAYGATCVDEIN---------------------GYRCSCPPGRAGPRCQEVIGFGRSC 834
Query: 325 ASR--PCLNGGHCQDLPNGFQCHCPDG-------YAG--PTCEEDVDECLSDPCLHGGTC 373
SR P +G + N C C DG + G P E LS C G C
Sbjct: 835 WSRGTPFPHGSSWVEDCN--SCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRC 892
Query: 374 SDTVAGYICRCP-ETWGGRDCSVQ---LTGCQGHTCPLAATCIPIFESGVHSYVCHCPPG 429
+ G R P E WG +C + T C + L C + +H H P G
Sbjct: 893 LEKAPGQCLRPPCEAWG--ECGAEEPPSTPCLPRSGHLDNNCARL---TLHFNRDHVPQG 947
Query: 430 T 430
T
Sbjct: 948 T 948
Score = 173 bits (439), Expect = 8e-43
Identities = 107/321 (33%), Positives = 145/321 (45%), Gaps = 48/321 (14%)
Query: 118 HHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYG 177
H +L + C Y TC C G D G+ C+ G+
Sbjct: 182 HFSGHVAHLELQIRVRCDENYYSATCNKF---CRPRNDFFGHYTCDQYGNKACM--DGWM 236
Query: 178 GTRCQLDLDECQSQPC--AHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHN 235
G C+ + Q C HGG V G C C+ G++G C+ EC P +
Sbjct: 237 GKECK---EAVCKQGCNLLHGGCT---VPG-ECRCS-YGWQGRFCD----ECVPYPGCVH 284
Query: 236 ASCLEGLGSFRCLCWPGYSGELCEVDEDECASS-PCQHGGRCLQRSDPALYGGVQAAFPG 294
SC+E ++C C + G LC+ D + C S PC +GG C+ ++P Y
Sbjct: 285 GSCVE---PWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCIN-AEPDQYR-------- 332
Query: 295 AFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPT 354
C CP G+ G +C C S PC NGG C ++P+GF+CHCP G++GPT
Sbjct: 333 -----------CTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPT 381
Query: 355 CEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPI 414
C D+DEC S+PC GGTC D V G+ C CPE W G C + + C+G C TC +
Sbjct: 382 CALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQ-CQHGGTCKDL 440
Query: 415 FESGVHSYVCHCPPGTHGPFC 435
V+ Y C CP G G C
Sbjct: 441 ----VNGYQCVCPRGFGGRHC 457
Score = 111 bits (278), Expect = 4e-24
Identities = 58/161 (36%), Positives = 74/161 (45%), Gaps = 6/161 (3%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTHPDGRFEC 1118
C +PC + G+C ++ F C C GW GP C +D C S PCA G C DG FEC
Sbjct: 351 CTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDG-FEC 409
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
CP + G C+L V +C C G C+ C C G G+ C++ C
Sbjct: 410 ICPEQWVGATCQLDV--NDC--RGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECA 465
Query: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGLPLPLP 1219
++PC +GG C C C FSG CEV L P P
Sbjct: 466 SSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSP 506
Score = 107 bits (268), Expect = 6e-23
Identities = 63/182 (34%), Positives = 77/182 (42%), Gaps = 23/182 (12%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
CA SPC G C DL D F C C G+ GP CE VD C +PC G RC+ + +G + C
Sbjct: 464 CASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCY-NLEGDYYC 522
Query: 1119 RCPPGFGGPRC---RLPVPSKECSLNVTC-LDGSPCEGGSPAA----------------- 1157
CP FGG C R P P C + C D P G+ A+
Sbjct: 523 ACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNF 582
Query: 1158 NCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGLPLP 1217
+C C G G C C PC NGGTC C C + + G+ C+ LP
Sbjct: 583 SCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP 642
Query: 1218 LP 1219
P
Sbjct: 643 DP 644
Score = 106 bits (265), Expect = 1e-22
Identities = 51/151 (33%), Positives = 65/151 (43%), Gaps = 2/151 (1%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C P PC G C DL + F CAC GW+G C + C + C+ G F C
Sbjct: 640 CLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCA 699
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
CPPG+ G C V L C++G C G + +C C +G G+ C T C
Sbjct: 700 CPPGWKGSTC--AVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNP 757
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
PC NGG C C C F+G C +
Sbjct: 758 LPCYNGGICVDGVNWFRCECAPGFAGPDCRI 788
Score = 102 bits (255), Expect = 2e-21
Identities = 55/151 (36%), Positives = 70/151 (46%), Gaps = 7/151 (4%)
Query: 1064 PCLHDGACRDLF-DAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFECRCP 1121
PC + G C + D + C C G+ G CE C S PCA G CH P G FEC CP
Sbjct: 316 PCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSG-FECHCP 374
Query: 1122 PGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANP 1181
G+ GP C L + EC+ N C G C C C E G CQ+ C
Sbjct: 375 SGWSGPTCALDI--DECASN-PCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQ- 430
Query: 1182 CLNGGTCRAAGGVSECICNARFSGQFCEVAK 1212
C +GGTC+ +C+C F G+ CE+ +
Sbjct: 431 CQHGGTCKDLVNGYQCVCPRGFGGRHCELER 461
Score = 89.0 bits (219), Expect = 3e-17
Identities = 42/112 (37%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C P+PC++ G C +F+C C GWEG C + + C+ PC G F C
Sbjct: 717 CLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCE 776
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQ 1171
C PGF GP CR+ + EC + C G+ C CSC G AG RCQ
Sbjct: 777 CAPGFAGPDCRINI--DECQ-SSPCAYGATCVDEINGYRCSCPPGRAGPRCQ 825
Score = 84.0 bits (206), Expect = 9e-16
Identities = 57/221 (25%), Positives = 74/221 (33%), Gaps = 62/221 (28%)
Query: 1059 VCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCA-------------- 1104
+C PSPC + C +L + CAC + G C +PC C
Sbjct: 501 LCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMP 560
Query: 1105 ----------RGRCHTHPDGRFECRCPPGFGGPRCRLPVPS---KECSLNVTCLDG---- 1147
GRC + P G F C C GF G C + + C TC+D
Sbjct: 561 GTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAF 620
Query: 1148 ----------------------SPCEGGSPAAN------CSCLEGLAGQRCQVPTLPCEA 1179
PC + C+C +G G+ C C+A
Sbjct: 621 RCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDA 680
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEVAKG---LPLP 1217
C NGGTC +G C C + G C VAK LP P
Sbjct: 681 YTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNP 721
Score = 83.6 bits (205), Expect = 1e-15
Identities = 46/132 (34%), Positives = 60/132 (45%), Gaps = 14/132 (10%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C P PC + G C D + F C C PG+ GP C ++D C S+PCA G + C
Sbjct: 755 CNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCS 814
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLD-GSPCEGGS----PAANCSCLEGLAGQRCQVPT 1174
CPPG GPRC+ + +C G+P GS +C CL+G R
Sbjct: 815 CPPGRAGPRCQ-----EVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDG----RRDCSK 865
Query: 1175 LPCEANPCLNGG 1186
+ C PCL G
Sbjct: 866 VWCGWKPCLLAG 877
Score = 64.3 bits (155), Expect = 7e-10
Identities = 38/117 (32%), Positives = 54/117 (46%), Gaps = 11/117 (9%)
Query: 759 WGGPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSEL-----GGRQSWNLTAGCVSEDMCSP 813
WGG C +DL G H P +++P + G N +E C+
Sbjct: 299 WGGLL--CDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEK---AEHACTS 353
Query: 814 DPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
+PC NGG+C + F C CP+ ++GPTCA + C PC TC + DGF C+
Sbjct: 354 NPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECI 410
Score = 55.8 bits (133), Expect = 3e-07
Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 796 RQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCL 854
R W + + C+P PC+NGG C+ N F C C F GP C + C PC
Sbjct: 740 RDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCA 799
Query: 855 PPATCEEVPDGFVC 868
ATC + +G+ C
Sbjct: 800 YGATCVDEINGYRC 813
Score = 54.3 bits (129), Expect = 7e-07
Identities = 28/87 (32%), Positives = 36/87 (41%), Gaps = 9/87 (10%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
+ D C+ PC +GG C + FHC CP F+GP C + C PC A C +
Sbjct: 459 LERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEG 518
Query: 865 GFVCVAEATFREGPPAAFSGHNASSGR 891
+ C P F G N S R
Sbjct: 519 DYYCAC--------PDDFGGKNCSVPR 537
Score = 53.5 bits (127), Expect = 1e-06
Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 799 WNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPA 857
W+ + D C+ +PC GGTC+ + F C CP + G TC + C GQ C
Sbjct: 377 WSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQ-CQHGG 435
Query: 858 TCEEVPDGFVCVAEATF 874
TC+++ +G+ CV F
Sbjct: 436 TCKDLVNGYQCVCPRGF 452
Score = 53.1 bits (126), Expect = 2e-06
Identities = 47/151 (31%), Positives = 59/151 (39%), Gaps = 29/151 (19%)
Query: 1073 DLFDAFAC------ACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRF---ECRCPPG 1123
D F + C AC GW G C+ A C +G C+ G ECRC G
Sbjct: 216 DFFGHYTCDQYGNKACMDGWMGKECK-------EAVCKQG-CNLLHGGCTVPGECRCSYG 267
Query: 1124 FGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEAN-PC 1182
+ G C EC C+ GS E C+C G C C ++ PC
Sbjct: 268 WQGRFC------DECVPYPGCVHGSCVEPWQ----CNCETNWGGLLCDKDLNYCGSHHPC 317
Query: 1183 LNGGTC-RAAGGVSECICNARFSGQFCEVAK 1212
NGGTC A C C +SG+ CE A+
Sbjct: 318 TNGGTCINAEPDQYRCTCPDGYSGRNCEKAE 348
Score = 53.1 bits (126), Expect = 2e-06
Identities = 76/289 (26%), Positives = 95/289 (32%), Gaps = 55/289 (19%)
Query: 614 CVHGGSCVDLWTHFRCDCARPHRGPTCA---DEIPAATFGLGG-----APSSASFLLQEL 665
C HGG+C DL ++C C R G C DE ++ GG A Q
Sbjct: 431 CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGF 490
Query: 666 PGPNLTVSFLL----------RTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAV 715
GP V L R G D G + R PG
Sbjct: 491 SGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVP----REPCPGGACR 546
Query: 716 VLPGRWDDGLRHLVMLSFGPDQLQDLGQHVHVGGRLLAADSQPWGGPFRGCLQDLRLDG- 774
V+ G D + G G H GR + SQP GG F C+ D G
Sbjct: 547 VIDGCGSDAGPGMP----GTAASGVCGPH----GRCV---SQP-GGNF-SCICDSGFTGT 593
Query: 775 -CHLPFFPLPLDNSSQPSELGGR-------------QSWNLTAGCVSEDMCSPDPCFNGG 820
CH D QP GG W + + C PDPC + G
Sbjct: 594 YCHENID----DCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRG 649
Query: 821 TCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFVC 868
C NDF+C C + G TC +++ C C TC + D F C
Sbjct: 650 RCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC 698
Score = 48.9 bits (115), Expect = 3e-05
Identities = 27/83 (32%), Positives = 35/83 (42%), Gaps = 6/83 (7%)
Query: 808 EDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC--AQQLWCPGQPCLPPATCEEVPDG 865
E C C NGGTC + + F C CP + G TC A+ C PC+ TC
Sbjct: 675 EFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGAS 734
Query: 866 FVCVAEATFREGPPAAFSGHNAS 888
F C+ R+G HN +
Sbjct: 735 FSCIC----RDGWEGRTCTHNTN 753
Score = 45.8 bits (107), Expect = 3e-04
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFV 867
D C PC NGGTC+ + F C CP+ + G C C PC C ++ + F
Sbjct: 600 DDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFY 659
Query: 868 CVAE 871
C +
Sbjct: 660 CACD 663
Score = 45.8 bits (107), Expect = 3e-04
Identities = 22/68 (32%), Positives = 28/68 (41%), Gaps = 1/68 (1%)
Query: 802 TAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCE 860
T C P+PC NGGTC+ + F C C + G TC C PC C
Sbjct: 708 TCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICV 767
Query: 861 EVPDGFVC 868
+ + F C
Sbjct: 768 DGVNWFRC 775
Score = 42.4 bits (98), Expect = 0.003
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 603 CERREQ-CRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
CE+ E C PC +GGSC ++ + F C C GPTCA +I
Sbjct: 344 CEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI 386
Score = 40.8 bits (94), Expect = 0.008
Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 6/53 (11%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL------WCPGQP 852
++ D C PC G TC+ N + C+CP GP C + + W G P
Sbjct: 788 INIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTP 840
Score = 39.7 bits (91), Expect = 0.019
Identities = 14/38 (36%), Positives = 21/38 (55%)
Query: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
++C+ PC +G +CVD +RC C GP C + I
Sbjct: 791 DECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVI 828
Score = 39.3 bits (90), Expect = 0.025
Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 603 CE-RREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
CE R++C PC GG C DL F C C + GP C ++
Sbjct: 457 CELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDV 499
Score = 38.5 bits (88), Expect = 0.042
Identities = 18/40 (45%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 603 CERRE-QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCA 641
C RE QC C +GG+C D FRC C +G TCA
Sbjct: 671 CHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCA 710
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 274 bits (700), Expect = 5e-73
Identities = 136/355 (38%), Positives = 189/355 (53%), Gaps = 39/355 (10%)
Query: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
FRC C PGF G CE++I+EC+S PC + TC +L +R+ C+C Y G CE++V++C
Sbjct: 912 FRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCK 971
Query: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA 211
+PCL +C+ + C+CAPGY G C+++LDEC S+PC H G C D +N + CDC
Sbjct: 972 ISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCK 1031
Query: 212 GTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQ 271
+G+ GTHCE +C S PC H C E + + C C + C++ ++C S PC
Sbjct: 1032 -SGFFGTHCETNANDCLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCM 1089
Query: 272 HGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECA-----S 326
+ G C Q+S A GF C CP G+ GA C +D CA S
Sbjct: 1090 NEGFC-QKS--------------------AHGFTCICPRGYTGAYCEKSIDNCAEPELNS 1128
Query: 327 RPCLNGGHCQDLP-NGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCP 385
CLNGG C D P + F C C G++G CE +++EC S PCLHG C D + GY+C+C
Sbjct: 1129 VICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQ 1188
Query: 386 ETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPG----THGPFCG 436
W G C +L C ++C + C+ C C PG + G CG
Sbjct: 1189 PGWSGHHCENELE-CIPNSC-VHELCM----ENEPGSTCLCTPGFMTCSIGLLCG 1237
Score = 271 bits (694), Expect = 2e-72
Identities = 141/454 (31%), Positives = 207/454 (45%), Gaps = 73/454 (16%)
Query: 47 CAPG---TECQAT--ESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQ 101
C PG T+C+ E + C C QP ++ CVP GF C C PG+
Sbjct: 669 CVPGFKGTQCEIDIDECASHPC--KNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYV 726
Query: 102 GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSC 161
G RCE DID+C C H +TC++L Y+C C + G CE E +EC PC + +C
Sbjct: 727 GIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTC 786
Query: 162 LDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHD--LVNGFRCDCAG--TG--- 214
D S+RC C G+ G C +++EC S PC +GG CH+ + F C C TG
Sbjct: 787 TDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFC 846
Query: 215 -----------------------------------YEGTHCEREVLECASAPCEHNASCL 239
+EG +CE +V +C C+ C
Sbjct: 847 HQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCE 906
Query: 240 EGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAF--- 296
+ + +FRC+C PG+SG LCE++ +EC+S PC++ G C+ ++ + + + G F
Sbjct: 907 DMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTN-RFFCNCEPEYHGPFCEL 965
Query: 297 ---------------SFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNG 341
G+ C C PG+ G +C + +DEC S PCL+ G C D N
Sbjct: 966 DVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINH 1025
Query: 342 FQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQ 401
+ C C G+ G CE + ++CLS+PCLH G C++ + Y C C C +++ C
Sbjct: 1026 YTCDCKSGFFGTHCETNANDCLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCT 1084
Query: 402 GHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
C C + H + C CP G G +C
Sbjct: 1085 SIPCMNEGFC----QKSAHGFTCICPRGYTGAYC 1114
Score = 251 bits (641), Expect = 3e-66
Identities = 136/430 (31%), Positives = 194/430 (45%), Gaps = 46/430 (10%)
Query: 27 LSLLAGTVPSEPPSACASDPCAPGTECQ--------ATESG--GYTCGPMEPRGCATQPC 76
LS G + + C +PC + C SG G C E C + PC
Sbjct: 760 LSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSE-EINECDSDPC 818
Query: 77 HHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDEC--ASRPCHHGATCRNLADRYE-CH 133
+G LC + P F C C P + G C + C PC + +TC L D + C
Sbjct: 819 MNGGLC-HESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCI 877
Query: 134 CPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPC 193
C + G CE++V +C C G C D V +FRC+C PG+ G+ C+++++EC S+PC
Sbjct: 878 CREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPC 937
Query: 194 AHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGY 253
+ GTC DL N F C+C Y G CE +V +C +PC +C+ + CLC PGY
Sbjct: 938 KNNGTCVDLTNRFFCNCEPE-YHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGY 996
Query: 254 SGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFE 313
+G CE++ DEC S PC H G C+ H + C C GF
Sbjct: 997 TGINCEINLDECLSEPCLHDGVCID------------------GINH---YTCDCKSGFF 1035
Query: 314 GADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTC 373
G C ++C S PCL+G C +L N + C C C+ +++C S PC++ G C
Sbjct: 1036 GTHCETNANDCLSNPCLHG-RCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFC 1094
Query: 374 SDTVAGYICRCPETWGGRDCSVQLTGC-----QGHTCPLAATCIPIFESGVHSYVCHCPP 428
+ G+ C CP + G C + C C C+ + H++ C C P
Sbjct: 1095 QKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICV---DGPGHTFDCRCLP 1151
Query: 429 GTHGPFCGQN 438
G G FC N
Sbjct: 1152 GFSGQFCEIN 1161
Score = 240 bits (612), Expect = 7e-63
Identities = 119/370 (32%), Positives = 181/370 (48%), Gaps = 41/370 (11%)
Query: 105 CELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDG 164
CE+D ++C S C +G T +L + C G+ G CE+++DECAS PC +G +C+D
Sbjct: 640 CEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQ 699
Query: 165 VGS--------------FRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDC 210
G+ F C+C PGY G RC+ D+D+C C H TC DL ++C C
Sbjct: 700 PGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVC 759
Query: 211 AGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPC 270
+ +EG CE+E EC PC++N++C + S+RC C G++G+ C + +EC S PC
Sbjct: 760 L-SDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPC 818
Query: 271 QHGGRCLQRSDPALYGGV-QAAFPGAFSFRH---------------------AAGFLCHC 308
+GG C + + P + + + G F + A C C
Sbjct: 819 MNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCIC 878
Query: 309 PPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCL 368
FEG +C ++V +C C + G C+D+ N F+C C G++G CE +++EC S+PC
Sbjct: 879 REEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCK 938
Query: 369 HGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPP 428
+ GTC D + C C + G C + + C+ C C+ Y C C P
Sbjct: 939 NNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCV----YRTDGYNCLCAP 994
Query: 429 GTHGPFCGQN 438
G G C N
Sbjct: 995 GYTGINCEIN 1004
Score = 201 bits (510), Expect = 5e-51
Identities = 111/359 (30%), Positives = 159/359 (44%), Gaps = 57/359 (15%)
Query: 42 CASDPCAPGTEC-QATESGGYTCGP--------MEPRGCATQPCHHGALCVPQGPDPTGF 92
C+S+PC C T C P ++ C PC CV + G+
Sbjct: 932 CSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYR---TDGY 988
Query: 93 RCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECAS 152
C C PG+ G CE+++DEC S PC H C + + Y C C G+ G CE ++C S
Sbjct: 989 NCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLS 1048
Query: 153 APCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAG 212
PCLH G C + + + C C T+C++ +++C S PC + G C +GF C C
Sbjct: 1049 NPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICP- 1106
Query: 213 TGYEGTHCEREVLECA-----SAPCEHNASCLEGLG-SFRCLCWPGYSGELCEVDEDECA 266
GY G +CE+ + CA S C + C++G G +F C C PG+SG+ CE++ +EC+
Sbjct: 1107 RGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECS 1166
Query: 267 SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECAS 326
SSPC HG C H G++C C PG+ G C E+ EC
Sbjct: 1167 SSPCLHGADCED---------------------HINGYVCKCQPGWSGHHCENEL-ECIP 1204
Query: 327 RPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCP 385
C++ C + G C C G+ C G C D + C P
Sbjct: 1205 NSCVH-ELCMENEPGSTCLCTPGFM--------------TCSIGLLCGDEIRRITCLTP 1248
Score = 185 bits (470), Expect = 2e-46
Identities = 106/337 (31%), Positives = 152/337 (45%), Gaps = 17/337 (5%)
Query: 117 CHHGATCRNLAD--RYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAP 174
C +G +C + D Y C L +AG + C H C D + RC C+
Sbjct: 535 CANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSL 594
Query: 175 GYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF--RCDCAGTG-YEGTHCEREVLECASAP 231
Y G C +++D C H + H L C+C+G YE CE + +C SA
Sbjct: 595 SYIGRLCVVNVDYCLGN---HSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSAS 651
Query: 232 CEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAA 291
C++ + G F C PG+ G CE+D DECAS PC++G C+ + P Y Q
Sbjct: 652 CKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQ--PGNYF-CQCV 708
Query: 292 FPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYA 351
P F+ GF C C PG+ G C ++D+C C + C+DL +QC C +
Sbjct: 709 PP----FKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWE 764
Query: 352 GPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATC 411
G CE++ +EC +PC + TC+D Y C C W G++CS ++ C C C
Sbjct: 765 GNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLC 824
Query: 412 IPIFESGVHSYVCHCPPGTHGPFCGQNTTFSVMAGSP 448
G +VC CPP G FC Q + +P
Sbjct: 825 HESTIPG--QFVCLCPPLYTGQFCHQRYNLCDLLHNP 859
Score = 121 bits (303), Expect = 5e-27
Identities = 81/310 (26%), Positives = 119/310 (38%), Gaps = 47/310 (15%)
Query: 130 YECHCPLGYAGVTCEMEVDECASAPCLHGGSCLD-----GVGSFRCVCAPGYGGTRCQLD 184
Y CHC ++G C+ E+D C+ PC + GSC++ ++ CVC P + G C
Sbjct: 198 YSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEI 256
Query: 185 LDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGS 244
+ +CQ C HG + N F C+C + G CE C S C +
Sbjct: 257 IGQCQPHVCFHGNCSNITSNSFICEC-DEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSA 315
Query: 245 FRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGF 304
+ C G S + E D E + PCQ+G C++ S+
Sbjct: 316 YTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDV--------------------- 354
Query: 305 LCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDEC-- 362
+C C P F C C S P N C+ + C C G+ CE+ +D C
Sbjct: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKL 414
Query: 363 LSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSY 422
LS CL+ C + + GR V + GC + C I H +
Sbjct: 415 LSINCLNEEWCFNII------------GRFKYVCIPGCTKNPCWFLKNVYLI-----HQH 457
Query: 423 VCHCPPGTHG 432
+C+C HG
Sbjct: 458 LCYCGVTFHG 467
Score = 110 bits (275), Expect = 9e-24
Identities = 103/445 (23%), Positives = 153/445 (34%), Gaps = 90/445 (20%)
Query: 41 ACASDPCAPGTEC----QATESGGYTC---GPMEPRGCAT-----QP--CHHGALCVPQG 86
AC+ PC C + + Y C P + C+ QP C HG
Sbjct: 216 ACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNC---SN 272
Query: 87 PDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME 146
F C C F GP CE+ C S C N + Y CP G + E +
Sbjct: 273 ITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETD 332
Query: 147 VDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF 206
V E + PC +G C+ C+C+P + C+ C+S P + TC +
Sbjct: 333 VSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDY 392
Query: 207 RCDCAGTGYEGTHCEREVLEC--ASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDE 264
C C +G+ +CE+ + C S C + C +G F+ +C PG
Sbjct: 393 PCSCI-SGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPG------------ 439
Query: 265 CASSPC----------QHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEG 314
C +PC QH C +G Q P F + GF G EG
Sbjct: 440 CTKNPCWFLKNVYLIHQHLCYC----GVTFHGICQDKGPAQFEYVWQLGF-----AGSEG 490
Query: 315 ADCGVEVD------------------------------ECASRPCLNGGHC--QDLPNGF 342
C +D E C NG C ++ +
Sbjct: 491 EKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEY 550
Query: 343 QCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQG 402
+ C +AG E+ + + C H C D + C C ++ GR C V + C G
Sbjct: 551 RYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLG 610
Query: 403 -HTCPLAATCIPIFESGVHSYVCHC 426
H+ + C+ + S+ C+C
Sbjct: 611 NHSISVHGLCLAL------SHNCNC 629
Score = 108 bits (269), Expect = 4e-23
Identities = 76/322 (23%), Positives = 123/322 (38%), Gaps = 36/322 (11%)
Query: 41 ACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGF 100
A PC G T + + C+ HG C+ + T + C+C P F
Sbjct: 153 ASGPSPCPLGLRLNVTVKQQFCQESLSSEFCSG----HGK-CLSEAWSKT-YSCHCQPPF 206
Query: 101 QGPRCELDIDECASRPCHHGATCRNLADR-----YECHCPLGYAGVTCEMEVDECASAPC 155
G C+ ++D C+ +PC + +C N + YEC C + G C + +C C
Sbjct: 207 SGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVC 265
Query: 156 LHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGY 215
HG SF C C + G C++ C S G C + + + +C G
Sbjct: 266 FHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECP-KGS 324
Query: 216 EGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGR 275
+ E +V E + PC++ C++ C+C P ++ LC+ + C S P ++
Sbjct: 325 SSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNAT 384
Query: 276 CLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDEC--ASRPCLNGG 333
C + + +P C C GF +C +D C S CLN
Sbjct: 385 CKK---------CEKDYP------------CSCISGFTEKNCEKAIDHCKLLSINCLNEE 423
Query: 334 HCQDLPNGFQCHCPDGYAGPTC 355
C ++ F+ C G C
Sbjct: 424 WCFNIIGRFKYVCIPGCTKNPC 445
Score = 99.8 bits (247), Expect = 2e-20
Identities = 50/150 (33%), Positives = 65/150 (43%), Gaps = 3/150 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C C G C D+ + F C C PG+ G CE ++ C S PC RF C
Sbjct: 894 CLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCN 953
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
C P + GP C L V +C ++ CLD C + NC C G G C++ C +
Sbjct: 954 CEPEYHGPFCELDV--NKCKIS-PCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLS 1010
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
PCL+ G C C C + F G CE
Sbjct: 1011 EPCLHDGVCIDGINHYTCDCKSGFFGTHCE 1040
Score = 99.8 bits (247), Expect = 2e-20
Identities = 60/190 (31%), Positives = 80/190 (42%), Gaps = 40/190 (21%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRC----HTHP--- 1112
C PCLHDG C D + + C C G+ G CE + + C S PC GRC + +P
Sbjct: 1008 CLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSC 1067
Query: 1113 --DGR----------------------------FECRCPPGFGGPRCRLPVPS-KECSLN 1141
DG F C CP G+ G C + + E LN
Sbjct: 1068 DADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELN 1127
Query: 1142 -VTCLDGSPC-EGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECIC 1199
V CL+G C +G +C CL G +GQ C++ C ++PCL+G C C C
Sbjct: 1128 SVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKC 1187
Query: 1200 NARFSGQFCE 1209
+SG CE
Sbjct: 1188 QPGWSGHHCE 1197
Score = 94.7 bits (234), Expect = 5e-19
Identities = 51/152 (33%), Positives = 70/152 (46%), Gaps = 6/152 (3%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCA-RGRCHTHPDGRFEC 1118
C+ PC ++G C DL + F C C P + GP CE V+ C +PC C DG + C
Sbjct: 932 CSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDG-YNC 990
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
C PG+ G C + + EC L+ CL C G C C G G C+ C
Sbjct: 991 LCAPGYTGINCEINL--DEC-LSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCL 1047
Query: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
+NPCL+ G C C C+A + C++
Sbjct: 1048 SNPCLH-GRCTELINEYPCSCDADGTSTQCKI 1078
Score = 94.4 bits (233), Expect = 6e-19
Identities = 49/160 (30%), Positives = 67/160 (41%), Gaps = 16/160 (10%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR-CHTHP-DGRFE 1117
C +PC ++ C DL+ ++ C C GW G C ++ C S PC G CH G+F
Sbjct: 775 CKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFV 834
Query: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAA-------NCSCLEGLAGQRC 1170
C CPP + G C N+ L +PC S +C C E G+ C
Sbjct: 835 CLCPPLYTGQFCHQ-------RYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNC 887
Query: 1171 QVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
++ C C + G C CIC FSG CE+
Sbjct: 888 EIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEI 927
Score = 83.6 bits (205), Expect = 1e-15
Identities = 56/201 (27%), Positives = 75/201 (37%), Gaps = 53/201 (26%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHP------ 1112
C + C + L F C PG++G +CE +D C S PC G C P
Sbjct: 647 CKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQ 706
Query: 1113 --------DGRFECRCPPGFGGPRCRLPVPS---KECSLNVTCLD--------------- 1146
DG F C C PG+ G RC + C N TC D
Sbjct: 707 CVPPFKVVDG-FSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEG 765
Query: 1147 -----------GSPCEGGSPAAN------CSCLEGLAGQRCQVPTLPCEANPCLNGGTCR 1189
+PC+ S + C C G GQ C C+++PC+NGG C
Sbjct: 766 NFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCH 825
Query: 1190 AA--GGVSECICNARFSGQFC 1208
+ G C+C ++GQFC
Sbjct: 826 ESTIPGQFVCLCPPLYTGQFC 846
Score = 82.8 bits (203), Expect = 2e-15
Identities = 47/156 (30%), Positives = 65/156 (41%), Gaps = 8/156 (5%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C + C H+ C+DL ++ C C WEG CE + C PC T + C
Sbjct: 737 CILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCE 796
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAAN--CSCLEGLAGQRCQVPTLPC 1177
C G+ G C + EC + C++G C + C C GQ C C
Sbjct: 797 CTSGWTGQNCSEEI--NECDSD-PCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLC 853
Query: 1178 EA--NPCLNGGTCRAAGGVSE-CICNARFSGQFCEV 1210
+ NPC N TC A ++ CIC F G+ CE+
Sbjct: 854 DLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEI 889
Score = 75.5 bits (184), Expect = 3e-13
Identities = 46/152 (30%), Positives = 63/152 (41%), Gaps = 11/152 (7%)
Query: 1069 GACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPR 1128
G C L C+ +E CE + C SA C G TH G F +C PGF G +
Sbjct: 618 GLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQ 677
Query: 1129 CRLPV---PSKECSLNVTCLDGSP---CEGGSP-----AANCSCLEGLAGQRCQVPTLPC 1177
C + + S C TC+D C+ P +C C G G RC+ C
Sbjct: 678 CEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDC 737
Query: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
N C + TC+ +C+C + + G FCE
Sbjct: 738 ILNACEHNSTCKDLHLSYQCVCLSDWEGNFCE 769
Score = 74.7 bits (182), Expect = 5e-13
Identities = 44/161 (27%), Positives = 64/161 (39%), Gaps = 8/161 (4%)
Query: 1054 CRGAPVCAPSPCLHDGAC---RDLFD--AFACACGPGWEGPRCEAHVDPCHSAPCARGRC 1108
C+ C+ PC ++G+C R+ +D A+ C C P + G C + C C G C
Sbjct: 211 CQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNC 270
Query: 1109 HTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQ 1168
F C C F GP C V +K C +++ C S A C +G + Q
Sbjct: 271 SNITSNSFICECDEQFSGPFCE--VSAKPC-VSLLFWKRGICPNSSSAYTYECPKGSSSQ 327
Query: 1169 RCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
+ PC NG C CIC+ F+ C+
Sbjct: 328 NGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCK 368
Score = 72.0 bits (175), Expect = 3e-12
Identities = 79/342 (23%), Positives = 129/342 (37%), Gaps = 45/342 (13%)
Query: 333 GHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCL-----HGGTCSDTVAGYICRCPET 387
GH + L N P+G+ P V +C + PC +GGTC ++ C C
Sbjct: 2588 GHFRGLGN------PEGH--PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTG 2639
Query: 388 WGGRDCSVQLTGCQ-----GHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFS 442
W G C+ ++ C H C ATCI + H Y C CP GT G +C Q + S
Sbjct: 2640 WKGSFCTETVSTCDPEHDPPHHCSRGATCISL----PHGYTCFCPLGTTGIYCEQALSIS 2695
Query: 443 VMAGSPIQ------ASVPAGGPLGLALRFRTTLPAGTL-----ATRNDTKESLELALVAA 491
+ + AS + L+F+ G L + + + L ++LV +
Sbjct: 2696 DPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNS 2755
Query: 492 TLQATLWSYSTTVLVLRLPDLALNDGHWH-----QVEVVLHLATLELRLWHEGCPARLCV 546
++Q T+++ L + +N WH +V +L + + + +
Sbjct: 2756 SVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSL 2815
Query: 547 ASGPVALASTASATPL--PAGISSAQLGDATFAGCLQDVRVDGHLLLPEDLGE--NVLLG 602
+ S+ L P I + +G F GC++ V ++ L + G +G
Sbjct: 2816 DTNTDFYIGGVSSLNLVNPMAIENEPVG---FQGCIRQVIINNQELQLTEFGAKGGSNVG 2872
Query: 603 CERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
C C +GG C T F C C G TC +
Sbjct: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV 2914
Score = 61.6 bits (148), Expect = 5e-09
Identities = 78/347 (22%), Positives = 117/347 (33%), Gaps = 65/347 (18%)
Query: 112 CASRPCHHGATCRNL-----ADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLD--- 163
C CH+G TC + ++C CPL + G CE D P +G S L+
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEK--DAGLFFPSFNGNSYLELPF 2160
Query: 164 -----------GVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAG 212
V + + GT + + C Q ++ F +
Sbjct: 2161 LKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQ----------FLHLFLVEGRP 2210
Query: 213 TGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQH 272
+ G + +L SA N + + + R G G +C ++ P
Sbjct: 2211 SVKYGCGNSQNILT-VSANYSINTNAFTPI-TIRYTTPVGSPGVVCMIEMTADGKPP--- 2265
Query: 273 GGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPG----FEGADCGVEVDECASRP 328
+Q+ D + QA F F A H G F G ++V+
Sbjct: 2266 ----VQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFI 2321
Query: 329 CLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETW 388
H +++ N CH P C C + GTC C CP +
Sbjct: 2322 IDEARHGKNIEN---CHVP-------------WCAHHLCRNNGTCISDNENLFCECPRLY 2365
Query: 389 GGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
G+ C Q C+ + C ATC+P +SG VC CP G GP C
Sbjct: 2366 SGKLC--QFASCENNPCGNGATCVP--KSGT-DIVCLCPYGRSGPLC 2407
Score = 59.3 bits (142), Expect = 2e-08
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 8/92 (8%)
Query: 58 SGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASR-- 115
+ G + G C+ C +G C+ G T C C G++G C + C
Sbjct: 2601 NAGRSVGQCHASPCSLMKCGNGGTCIESG---TSVYCNCTTGWKGSFCTETVSTCDPEHD 2657
Query: 116 PCHH---GATCRNLADRYECHCPLGYAGVTCE 144
P HH GATC +L Y C CPLG G+ CE
Sbjct: 2658 PPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 58.5 bits (140), Expect = 4e-08
Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C+ SPCLH C D + + C C PGW G CE ++ C C C + G C
Sbjct: 1165 CSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELE-CIPNSCVHELCMENEPGS-TCL 1222
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCL 1145
C PGF C + + + +TCL
Sbjct: 1223 CTPGF--MTCSIGLLCGDEIRRITCL 1246
Score = 58.2 bits (139), Expect = 5e-08
Identities = 101/474 (21%), Positives = 165/474 (34%), Gaps = 87/474 (18%)
Query: 699 FLSEGRIRAEVPGSPAVVLPGRWDDGLRHLVMLSFGPDQLQDLGQHVHVGGRL-LAADSQ 757
F EG ++ + + +++ PGR LV L+ + +VGG D
Sbjct: 2519 FFQEGWLKVDDHKNKSIIAPGR-------LVGLN--------VFSQFYVGGYSEYTPDLL 2563
Query: 758 PWGGPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELG-----GRQSWNLTAGCVSEDMCS 812
P G F+ Q GC F L + G G + + G CS
Sbjct: 2564 PNGADFKNGFQ-----GC---IFTLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASPCS 2615
Query: 813 PDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWC------PGQPCLPPATCEEVPDGF 866
C NGGTC+ + +C C + G C + + P C ATC +P G+
Sbjct: 2616 LMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGY 2675
Query: 867 VC----------------VAEATFREGPPAAFSGHNASSGRLLGGLSLAFRTRDSEAWLL 910
C +++ +FR ++ + R + L F+ ++ L
Sbjct: 2676 TCFCPLGTTGIYCEQALSISDPSFRSN-ELSWMSFASFHVRKKTHIQLQFQPLAADGILF 2734
Query: 911 RAA--AGALEGVWLAVRNGSLAGGVRGGHGLPGAVLPIPGPRVADGA-WHRVRLAMERPA 967
AA A G +L + + + +R G +L +G+ WH + +
Sbjct: 2735 YAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHII-----KAG 2789
Query: 968 ATTSRWLLWLDG------AATPVALRGLASD--LGFLQGPGAVRILLAEN----FTGCLG 1015
+ L LDG A+T ++ +D +G + V + EN F GC+
Sbjct: 2790 RVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIR 2849
Query: 1016 RVALGGLPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLF 1075
+V + L L GA G+ + C G C + C + G C
Sbjct: 2850 QVIINNQELQLT--EFGAKGGSN------------VGDCDGT-ACGYNTCRNGGECTVNG 2894
Query: 1076 DAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRC 1129
F+C C P W G C V ++ + C + C C G+ G C
Sbjct: 2895 TTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYC 2948
Score = 55.8 bits (133), Expect = 3e-07
Identities = 28/71 (39%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 324 CASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTC-SDTVAGYIC 382
C C NGG C F C C +AG TC + V CL++ CLH C D Y C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 383 RCPETWGGRDC 393
C W GR C
Sbjct: 2938 LCTLGWVGRYC 2948
Score = 53.5 bits (127), Expect = 1e-06
Identities = 47/180 (26%), Positives = 69/180 (38%), Gaps = 16/180 (8%)
Query: 358 DVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFES 417
D C + C +GG C+ + CRC W G C+ Q C + C + CIP
Sbjct: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSCLNNLCLHQSLCIP---D 2930
Query: 418 GVHSYVCHCPPGTHGPFCGQNTTFSV---MAGSPIQASVPAGGPLGL-----ALRFRTTL 469
SY C C G G +C T+FS M S I+ P L +L F TT
Sbjct: 2931 QSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTK 2990
Query: 470 PAGTLA----TRNDTKESLELALVAATLQATLWSYSTTVLVLRLPDLALNDGHWHQVEVV 525
G + +N+ + L + L TL+ + + + + WH V V+
Sbjct: 2991 TEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVI 3050
Score = 52.0 bits (123), Expect = 4e-06
Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
Query: 52 ECQATE---SGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELD 108
E Q TE GG G + C C +G C G T F C C+P + G C
Sbjct: 2857 ELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNG---TTFSCRCLPDWAGNTCNQS 2913
Query: 109 IDECASRPCHHGATC-RNLADRYECHCPLGYAGVTCE 144
+ C + C H + C + + Y C C LG+ G CE
Sbjct: 2914 VS-CLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 51.2 bits (121), Expect = 6e-06
Identities = 23/60 (38%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
CS +PC N GTC+ N F C C + GP C + C PCL C DG+ C+
Sbjct: 932 CSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCL 991
Score = 50.4 bits (119), Expect = 1e-05
Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEE--VPDGFV 867
C +PC N TC + + C C + +TG C++++ C PC+ C E +P FV
Sbjct: 775 CKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFV 834
Query: 868 CV 869
C+
Sbjct: 835 CL 836
Score = 50.4 bits (119), Expect = 1e-05
Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 11/86 (12%)
Query: 147 VDECASAPCL-----HGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQ-----PCAHG 196
V +C ++PC +GG+C++ S C C G+ G+ C + C + C+ G
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 197 GTCHDLVNGFRCDCAGTGYEGTHCER 222
TC L +G+ C C G G +CE+
Sbjct: 2666 ATCISLPHGYTCFCP-LGTTGIYCEQ 2690
Score = 50.1 bits (118), Expect = 1e-05
Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 3/98 (3%)
Query: 1116 FECRCPPGFGGPRCR-LPVPS-KECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVP 1173
+ C C P F G C+ L S K C N +C++ A C C G+ C
Sbjct: 198 YSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRE-NWDEQAYECVCHPPFTGKNCSEI 256
Query: 1174 TLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVA 1211
C+ + C +G C C+ +FSG FCEV+
Sbjct: 257 IGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVS 294
Score = 47.4 bits (111), Expect = 9e-05
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Query: 106 ELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCL-DG 164
+ D C C +G C + C C +AG TC V C + CLH C+ D
Sbjct: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
Query: 165 VGSFRCVCAPGYGGTRCQ 182
S+ C+C G+ G C+
Sbjct: 2932 SFSYSCLCTLGWVGRYCE 2949
Score = 47.0 bits (110), Expect = 1e-04
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 6/91 (6%)
Query: 174 PGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLEC-----A 228
P G + Q C C +GGTC + C+C TG++G+ C V C
Sbjct: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCT-TGWKGSFCTETVSTCDPEHDP 2658
Query: 229 SAPCEHNASCLEGLGSFRCLCWPGYSGELCE 259
C A+C+ + C C G +G CE
Sbjct: 2659 PHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 43.5 bits (101), Expect = 0.001
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 3/72 (4%)
Query: 324 CASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTC-SDTVAGYIC 382
CA C N G C C CP Y+G C+ C ++PC +G TC + +C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVC 2396
Query: 383 RCPETWGGRDCS 394
CP G C+
Sbjct: 2397 LCPYGRSGPLCT 2408
Score = 42.0 bits (97), Expect = 0.004
Identities = 69/309 (22%), Positives = 106/309 (34%), Gaps = 83/309 (26%)
Query: 609 CRPLPCVHGGSCVDLW-----THFRCDCARPHRGPTCADEIPAATFGLGGAP----SSAS 659
C+ C +GG+C ++ F+CDC G C + G
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELPFLK 2162
Query: 660 FLLQELPGPNLTVSFLLRTRESAGLLLQFANDSAAG---LTVFLSEGR------------ 704
F+L++ +T+ ++T G +L ++N + G L +FL EGR
Sbjct: 2163 FVLEKEHNRTVTIYLTIKTNSLNGTIL-YSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQN 2221
Query: 705 -------------------IRAEVP-GSPAVVLP-----------GRWDDGLRHLVMLSF 733
IR P GSP VV + D + H F
Sbjct: 2222 ILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYF 2281
Query: 734 GPDQLQDLGQHVHVGGRLLAADSQPWGGP---FRGCLQDLRLDGCHLPFFPLPLDNSSQP 790
L + +V + + GP FRGC+ DL+++ + FF + +
Sbjct: 2282 ESMFLGHIPANVQIHKK---------AGPVYGFRGCILDLQVN--NKEFFIIDEARHGKN 2330
Query: 791 SELGGRQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPG 850
E W C+ C N GTC+ + C CP ++G C Q C
Sbjct: 2331 IE-NCHVPW-----------CAHHLCRNNGTCISDNENLFCECPRLYSGKLC-QFASCEN 2377
Query: 851 QPCLPPATC 859
PC ATC
Sbjct: 2378 NPCGNGATC 2386
Score = 42.0 bits (97), Expect = 0.004
Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 3/75 (4%)
Query: 1144 CLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVS-ECICNAR 1202
C + C + C C +G+ CQ + CE NPC NG TC G C+C
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPKSGTDIVCLCPYG 2401
Query: 1203 FSGQFCEVAKGLPLP 1217
SG C A + P
Sbjct: 2402 RSGPLCTDAINITQP 2416
Score = 41.6 bits (96), Expect = 0.005
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 3/75 (4%)
Query: 150 CASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTC-HDLVNGFRC 208
C C +GG C +F C C P + G C + C + C H C D + C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 209 DCAGTGYEGTHCERE 223
C G+ G +CE +
Sbjct: 2938 LCT-LGWVGRYCENK 2951
Score = 41.6 bits (96), Expect = 0.005
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 3/73 (4%)
Query: 1138 CSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVS-E 1196
C N TC +G C +C CL AG C ++ C N CL+ C S
Sbjct: 2879 CGYN-TCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSCLNNLCLHQSLCIPDQSFSYS 2936
Query: 1197 CICNARFSGQFCE 1209
C+C + G++CE
Sbjct: 2937 CLCTLGWVGRYCE 2949
Score = 41.2 bits (95), Expect = 0.006
Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 7/75 (9%)
Query: 188 CQSQPCAHGGTCHDLVNG--FRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLG-S 244
C C +GG C VNG F C C + G C + V C + C H + C+ S
Sbjct: 2879 CGYNTCRNGGEC--TVNGTTFSCRCL-PDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFS 2934
Query: 245 FRCLCWPGYSGELCE 259
+ CLC G+ G CE
Sbjct: 2935 YSCLCTLGWVGRYCE 2949
Score = 40.8 bits (94), Expect = 0.008
Identities = 15/43 (34%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 603 CERRE-QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
CE+ +C+ PC + +C DL+ +RC+C G C++EI
Sbjct: 768 CEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEI 810
Score = 40.4 bits (93), Expect = 0.011
Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 7/80 (8%)
Query: 805 CVSEDMCSPDPCFNGGTCL---VTWND--FHCTCPANFTGPTCAQQL-WCPGQPCLPPAT 858
C D CS PC N G+C+ W++ + C C FTG C++ + C C
Sbjct: 211 CQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNC 270
Query: 859 CEEVPDGFVCVAEATFREGP 878
+ F+C + F GP
Sbjct: 271 SNITSNSFICECDEQF-SGP 289
Score = 40.4 bits (93), Expect = 0.011
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
++ D C +PC + G C+ N + C C + F G C C PCL C E+ +
Sbjct: 1003 INLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCL-HGRCTELIN 1061
Query: 865 GFVCVAEA 872
+ C +A
Sbjct: 1062 EYPCSCDA 1069
Score = 40.4 bits (93), Expect = 0.011
Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 2/60 (3%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
C +PC +G C N++ C+C A+ T C ++ C PC+ C++ GF C+
Sbjct: 1046 CLSNPCLHG-RCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCI 1104
Score = 40.4 bits (93), Expect = 0.011
Identities = 20/76 (26%), Positives = 28/76 (36%), Gaps = 5/76 (6%)
Query: 112 CASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC-----ASAPCLHGGSCLDGVG 166
C+ C +G TC C+C G+ G C V C C G +C+
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
Query: 167 SFRCVCAPGYGGTRCQ 182
+ C C G G C+
Sbjct: 2674 GYTCFCPLGTTGIYCE 2689
Score = 39.7 bits (91), Expect = 0.019
Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 11/93 (11%)
Query: 783 PLDNSSQPSELGGRQSWNLTAGCVSEDM------CSPDPCFNGGTCLVTW--NDFHCTCP 834
P N+S ++L T+G ++ C DPC NGG C + F C CP
Sbjct: 779 PCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCP 838
Query: 835 ANFTGPTCAQQL-WCP--GQPCLPPATCEEVPD 864
+TG C Q+ C PC +TC + D
Sbjct: 839 PLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVD 871
Score = 39.7 bits (91), Expect = 0.019
Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 816 CFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCVAEATF 874
C + G C N+F C C F+G C ++ C +PC TC ++ + F C E +
Sbjct: 899 CQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEY 958
Query: 875 REGP 878
GP
Sbjct: 959 -HGP 961
Score = 39.7 bits (91), Expect = 0.019
Identities = 21/46 (45%), Positives = 27/46 (58%), Gaps = 5/46 (10%)
Query: 1177 CEANPCLNGGTCRA----AGGVS-ECICNARFSGQFCEVAKGLPLP 1217
C+ + C NGGTC A +G VS +C C F+G+FCE GL P
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFP 2148
Score = 39.3 bits (90), Expect = 0.025
Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 1/65 (1%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
C PC + C+ + ++C C +TG C L C +PCL C + + + C
Sbjct: 970 CKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCD 1029
Query: 870 AEATF 874
++ F
Sbjct: 1030 CKSGF 1034
Score = 38.9 bits (89), Expect = 0.032
Identities = 14/33 (42%), Positives = 19/33 (57%)
Query: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
+C PC + G+CVDL F C+C + GP C
Sbjct: 931 ECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC 963
Score = 38.9 bits (89), Expect = 0.032
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 3/59 (5%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVPDGFVCV 869
C+ PC N G C + + F C CP +TG C + + +P L C +G +CV
Sbjct: 1083 CTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVIC---LNGGICV 1138
Score = 38.9 bits (89), Expect = 0.032
Identities = 23/97 (23%), Positives = 35/97 (36%), Gaps = 24/97 (24%)
Query: 265 CASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDEC 324
CA C++ G C+ ++ C CP + G C + C
Sbjct: 2339 CAHHLCRNNGTCISDNE---------------------NLFCECPRLYSGKLC--QFASC 2375
Query: 325 ASRPCLNGGHCQDLPN-GFQCHCPDGYAGPTCEEDVD 360
+ PC NG C C CP G +GP C + ++
Sbjct: 2376 ENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
Score = 38.5 bits (88), Expect = 0.042
Identities = 19/64 (29%), Positives = 26/64 (40%), Gaps = 1/64 (1%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVPDGFVCVA 870
CS PC +G C N + C C ++G C +L C C+ E P G C+
Sbjct: 1165 CSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEP-GSTCLC 1223
Query: 871 EATF 874
F
Sbjct: 1224 TPGF 1227
Score = 38.1 bits (87), Expect = 0.055
Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 7/60 (11%)
Query: 584 RVDGH--LLLPEDLGENVLLGCE-RREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
R DG+ L P G N CE ++C PC+H G C+D H+ CDC G C
Sbjct: 984 RTDGYNCLCAPGYTGIN----CEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHC 1039
Score = 38.1 bits (87), Expect = 0.055
Identities = 22/73 (30%), Positives = 28/73 (38%), Gaps = 3/73 (4%)
Query: 1058 PVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRF 1116
P CA C ++G C + C C + G C+ C + PC G C
Sbjct: 2337 PWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDI 2394
Query: 1117 ECRCPPGFGGPRC 1129
C CP G GP C
Sbjct: 2395 VCLCPYGRSGPLC 2407
Score = 37.7 bits (86), Expect = 0.071
Identities = 14/32 (43%), Positives = 17/32 (53%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC 842
C P CF+G +T N F C C F+GP C
Sbjct: 260 CQPHVCFHGNCSNITSNSFICECDEQFSGPFC 291
Score = 37.7 bits (86), Expect = 0.071
Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 1/63 (1%)
Query: 815 PCFNGGTCLVTWNDFHCTCPANFTGPTCAQ-QLWCPGQPCLPPATCEEVPDGFVCVAEAT 873
PC NG C+ ND C C FT C Q C P ATC++ + C +
Sbjct: 340 PCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISG 399
Query: 874 FRE 876
F E
Sbjct: 400 FTE 402
Score = 37.7 bits (86), Expect = 0.071
Identities = 23/85 (27%), Positives = 33/85 (38%), Gaps = 6/85 (7%)
Query: 1138 CSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA-----NPCLNGGTCRAAG 1192
CSL + C +G C + C+C G G C C+ + C G TC +
Sbjct: 2614 CSL-MKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLP 2672
Query: 1193 GVSECICNARFSGQFCEVAKGLPLP 1217
C C +G +CE A + P
Sbjct: 2673 HGYTCFCPLGTTGIYCEQALSISDP 2697
Score = 37.0 bits (84), Expect = 0.12
Identities = 33/115 (28%), Positives = 43/115 (37%), Gaps = 13/115 (11%)
Query: 1109 HTHPDGRFECR----CPPGFGGPRCR--LPVPSKECSLNVT-CLDGSP------CEGGSP 1155
+T D EC+ C PRC L + C +NV CL C S
Sbjct: 566 NTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSH 625
Query: 1156 AANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
NCS L+ C++ T C++ C NG T G C F G CE+
Sbjct: 626 NCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEI 680
Score = 37.0 bits (84), Expect = 0.12
Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 5/48 (10%)
Query: 800 NLTAGCVSEDMCSPDPCFNGGTCLVTW-----NDFHCTCPANFTGPTC 842
+++ + +C D C NGGTC + F C CP +FTG C
Sbjct: 2092 SVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFC 2139
Score = 35.4 bits (80), Expect = 0.35
Identities = 19/63 (30%), Positives = 27/63 (42%), Gaps = 2/63 (3%)
Query: 814 DPCFNGGTCLVTWN-DFHCTCPANFTGPTCAQQLW-CPGQPCLPPATCEEVPDGFVCVAE 871
+PC N TCL + + HC C F G C + C C CE++ + F C+
Sbjct: 858 NPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICR 917
Query: 872 ATF 874
F
Sbjct: 918 PGF 920
Score = 35.4 bits (80), Expect = 0.35
Identities = 26/106 (24%), Positives = 36/106 (33%), Gaps = 31/106 (29%)
Query: 222 REVLECASAPCE-----HNASCLEGLGSFRCLCWPGYSGELC-----EVDEDECASSPCQ 271
R V +C ++PC + +C+E S C C G+ G C D + C
Sbjct: 2604 RSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCS 2663
Query: 272 HGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADC 317
G C+ S H G+ C CP G G C
Sbjct: 2664 RGATCI-------------------SLPH--GYTCFCPLGTTGIYC 2688
Score = 35.4 bits (80), Expect = 0.35
Identities = 27/93 (29%), Positives = 35/93 (37%), Gaps = 10/93 (10%)
Query: 1088 GPRCEAHVDPCHSAPCARGRCH-----THPDGRFECRCPPGFGGPRCRLPVPSKECSLNV 1142
G + ++V C C C T F CRC P + G C V LN
Sbjct: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV----SCLNN 2919
Query: 1143 TCLDGSPC-EGGSPAANCSCLEGLAGQRCQVPT 1174
CL S C S + +C C G G+ C+ T
Sbjct: 2920 LCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKT 2952
Score = 35.0 bits (79), Expect = 0.46
Identities = 14/33 (42%), Positives = 16/33 (48%)
Query: 1176 PCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
PC C NGGTC +G C C + G FC
Sbjct: 2613 PCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFC 2645
Score = 33.9 bits (76), Expect = 1.0
Identities = 20/76 (26%), Positives = 30/76 (39%), Gaps = 15/76 (19%)
Query: 809 DMCSPDPCFNGGTCL--------------VTWNDFHCTCPANFTGPTCAQQL-WCPGQPC 853
D C+ PC NG TC+ + F C C + G C Q + C C
Sbjct: 683 DECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNAC 742
Query: 854 LPPATCEEVPDGFVCV 869
+TC+++ + CV
Sbjct: 743 EHNSTCKDLHLSYQCV 758
Score = 33.5 bits (75), Expect = 1.3
Identities = 19/71 (26%), Positives = 25/71 (35%), Gaps = 1/71 (1%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
+ + C C NG T F C F G C + C PC ATC + P
Sbjct: 642 IDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPG 701
Query: 865 GFVCVAEATFR 875
+ C F+
Sbjct: 702 NYFCQCVPPFK 712
Score = 33.1 bits (74), Expect = 1.8
Identities = 16/61 (26%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D C + C + TC + C C +++ G C Q+ C PC +TC ++ +
Sbjct: 735 DDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYR 794
Query: 868 C 868
C
Sbjct: 795 C 795
Score = 33.1 bits (74), Expect = 1.8
Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 2/35 (5%)
Query: 71 CATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRC 105
C PC +GA CVP+ T C C G GP C
Sbjct: 2375 CENNPCGNGATCVPK--SGTDIVCLCPYGRSGPLC 2407
Score = 33.1 bits (74), Expect = 1.8
Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 12/79 (15%)
Query: 576 FAGCLQDVRV----DGH---LLLPE---DLGENVLLGCERREQCRPLPCVHGGSCVDLWT 625
F GC+ ++V DGH L PE + G +V G C + C +GG+C++ T
Sbjct: 2573 FQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGRSV--GQCHASPCSLMKCGNGGTCIESGT 2630
Query: 626 HFRCDCARPHRGPTCADEI 644
C+C +G C + +
Sbjct: 2631 SVYCNCTTGWKGSFCTETV 2649
Score = 32.7 bits (73), Expect = 2.3
Identities = 18/66 (27%), Positives = 27/66 (40%), Gaps = 2/66 (3%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCH--SAPCARGRCHTHPDGRFE 1117
C P ++ C+ + C+C G+ CE +D C S C + GRF+
Sbjct: 374 CESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFK 433
Query: 1118 CRCPPG 1123
C PG
Sbjct: 434 YVCIPG 439
Score = 32.7 bits (73), Expect = 2.3
Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 3/80 (3%)
Query: 359 VDECLSDPCLHGGTCSDTVAGYICRCPET-WGGRDCSVQLTG-CQGHTCPLAATCIPIF- 415
++ C S + T S A + + +T W SV CQ C TC IF
Sbjct: 2060 INNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFL 2119
Query: 416 ESGVHSYVCHCPPGTHGPFC 435
SG+ S+ C CP G FC
Sbjct: 2120 SSGIVSFQCDCPLHFTGRFC 2139
Score = 32.3 bits (72), Expect = 3.0
Identities = 17/69 (24%), Positives = 24/69 (34%), Gaps = 13/69 (18%)
Query: 209 DCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASS 268
DC GT C C + C +F C C P ++G C C ++
Sbjct: 2873 DCDGTA------------CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSCLNN 2919
Query: 269 PCQHGGRCL 277
C H C+
Sbjct: 2920 LCLHQSLCI 2928
Score = 32.0 bits (71), Expect = 3.9
Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 4/67 (5%)
Query: 579 CLQDVRVDGHLLLPEDL-GENVLLGCERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRG 637
CL V + H + E+ G+N + + C L C G C D+ +FRC C G
Sbjct: 866 CLALVDANQHCICREEFEGKNCEIDVK---DCLFLSCQDYGDCEDMVNNFRCICRPGFSG 922
Query: 638 PTCADEI 644
C EI
Sbjct: 923 SLCEIEI 929
Score = 31.6 bits (70), Expect = 5.1
Identities = 12/37 (32%), Positives = 17/37 (45%)
Query: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
+C PC+HG C D + C C G C +E+
Sbjct: 1164 ECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENEL 1200
Score = 30.8 bits (68), Expect = 8.7
Identities = 14/47 (29%), Positives = 22/47 (46%), Gaps = 5/47 (10%)
Query: 603 CERREQCRPLPCVHGGSCV---DLWTH--FRCDCARPHRGPTCADEI 644
C+ + C PC + GSC+ + W + C C P G C++ I
Sbjct: 211 CQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEII 257
Score = 30.8 bits (68), Expect = 8.7
Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 1168 QRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVA 1211
+ C VP C + C N GTC + C C +SG+ C+ A
Sbjct: 2332 ENCHVPW--CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA 2373
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 256 bits (655), Expect = 7e-68
Identities = 145/427 (33%), Positives = 185/427 (43%), Gaps = 64/427 (14%)
Query: 46 PCAPGTECQ-----ATESGGYTC--------GPMEPRGCATQPCHHGALCVPQGPDPTGF 92
PC T+C G Y C P C + PC +G C +
Sbjct: 507 PCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSC---DAHDDSY 563
Query: 93 RCYCVPGFQGPRCELDIDE-CASRPCHHGATCRNLADRYECHCPLGYAGVTCEM-EVDEC 150
C C GF G CE C+S PC +G TC+ Y C CP + G CE+ + D C
Sbjct: 564 TCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSC 623
Query: 151 ASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDC 210
AS PC +GG+C +G ++C C PG+ G C++ C PC +GGTC D F C C
Sbjct: 624 ASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHC 683
Query: 211 AGTGYEGTHCEREV-----LECASAPCEHNASCLEGLGSFRC-------------LCWP- 251
GY G C+ EV E A N + L + + C +C P
Sbjct: 684 QA-GYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPH 742
Query: 252 GYSGELCEVDE-DECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPP 310
G E + E DEC S PC HGG C R AG+LC C
Sbjct: 743 GVWSEPPQCLEIDECRSQPCLHGGSCQDR---------------------VAGYLCLCST 781
Query: 311 GFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHG 370
G+EGA C +E DEC + PC NGG C++LP + C CP G+ G CE +VD C S PC HG
Sbjct: 782 GYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHG 841
Query: 371 GTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGT 430
G C Y+C CPE++ G C C C C+ +G HS C C G
Sbjct: 842 GRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLA--SNGSHS--CTCKVGY 897
Query: 431 HGPFCGQ 437
G C +
Sbjct: 898 TGEDCAK 904
Score = 249 bits (637), Expect = 9e-66
Identities = 136/400 (34%), Positives = 185/400 (46%), Gaps = 37/400 (9%)
Query: 63 CGPMEPRGCATQPCHHGALCVPQGPDPT-GFRCYCVPGFQGPRCELDIDECASRPCHHGA 121
CG A +PC +G C+ + C C+ GF G RC LD++ECAS+PC +G
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
Query: 122 TCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRC 181
TC + + + C CP G+ G TCE C + C HGG C GS CVC GY G C
Sbjct: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
Query: 182 QLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCE---REVLE-CASAPCEHNAS 237
++D+D+C PC +GG+C DLV + C CA ++G CE V + C SAPC + +
Sbjct: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCA-EPFKGLRCETGDHPVPDACLSAPCHNGGT 443
Query: 238 CLEGLGSFRCLCWPGYSGELC-EVDEDECASSPCQHGGRCLQRSD-----PALYGGVQAA 291
C++ + C C G+ G C E D+C C++GGRCL + P + G+
Sbjct: 444 CVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLGANTTLCQCPLGFFGLLCE 500
Query: 292 F--------------PGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQD 337
F G + H +LC C + C S PC NGG C
Sbjct: 501 FEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHS--LPSPCDSDPCFNGGSCDA 558
Query: 338 LPNGFQCHCPDGYAGPTCEEDVDE-CLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSV- 395
+ + C CP G+ G CE+ C S PC +GGTC + Y C CP + GR C +
Sbjct: 559 HDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIG 618
Query: 396 QLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
+ C C TC + Y C CPPG G C
Sbjct: 619 KPDSCASGPCHNGGTCFHY----IGKYKCDCPPGFSGRHC 654
Score = 245 bits (625), Expect = 2e-64
Identities = 133/390 (34%), Positives = 176/390 (45%), Gaps = 56/390 (14%)
Query: 39 PSACASDPCAPGTECQATESG----------GYTCGPMEPRGCATQPCHHGALCVPQGPD 88
PS C SDPC G C A + G C P C++ PC +G C G +
Sbjct: 542 PSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGE 601
Query: 89 PTGFRCYCVPGFQGPRCELDI-DECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEV 147
+ C C F G CE+ D CAS PCH+G TC + +Y+C CP G++G CE+
Sbjct: 602 ---YHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAP 658
Query: 148 DECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLD-----ECQSQPCAHGGTCHDL 202
C +PC++GG+C D F C C GY G RCQ ++D E + GT
Sbjct: 659 SPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGA 718
Query: 203 VNGFRCDCA---------------GTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRC 247
V + CD G E C E+ EC S PC H SC + + + C
Sbjct: 719 VALYACDRGYSLSAPSRIRVCQPHGVWSEPPQC-LEIDECRSQPCLHGGSCQDRVAGYLC 777
Query: 248 LCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCH 307
LC GY G CE++ DEC + PC++GG C PGA+ +C
Sbjct: 778 LCSTGYEGAHCELERDECRAHPCRNGGSCRN-------------LPGAY--------VCR 816
Query: 308 CPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPC 367
CP GF G C EVD C S PC +GG C+ + C CP+ + G CE D C S PC
Sbjct: 817 CPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPC 876
Query: 368 LHGGTCSDTVAGYICRCPETWGGRDCSVQL 397
G C + + C C + G DC+ +L
Sbjct: 877 GGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 218 bits (555), Expect = 3e-56
Identities = 152/540 (28%), Positives = 209/540 (38%), Gaps = 146/540 (27%)
Query: 42 CASDPCAPGTECQ----------ATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTG 91
CAS PC G C GG TC + C T+ C HG C +
Sbjct: 315 CASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQ-SPCDTKECQHGGQCQVENGSAV- 372
Query: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEM----EV 147
C C G+ G CE+D+D+C+ PC +G +C +L Y C C + G+ CE
Sbjct: 373 --CVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVP 430
Query: 148 DECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDL-DECQSQPCAHGGTCHDLVNGF 206
D C SAPC +GG+C+D + C C G+ G C+ + D+C+ C +GG C N
Sbjct: 431 DACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLG-ANTT 486
Query: 207 RCDCAGTGYEGTHCEREV--LEC-ASAPCEHNASCLEGLGSFRCLCW------------- 250
C C G+ G CE E+ + C + C C+E GS+ C+C
Sbjct: 487 LCQCP-LGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPC 545
Query: 251 ---PGYSGELCEVDEDE---------------------CASSPCQHGGRCLQR------S 280
P ++G C+ +D C+S PC++GG C + S
Sbjct: 546 DSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCS 605
Query: 281 DPALYGGVQ---------AAFP---GAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRP 328
P + G A+ P G F + + C CPPGF G C + C P
Sbjct: 606 CPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSP 665
Query: 329 CLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVD---------------------------- 360
C+NGG C+D F CHC GY G C+ +VD
Sbjct: 666 CVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACD 725
Query: 361 ------------------------ECLS-DPC-----LHGGTCSDTVAGYICRCPETWGG 390
+CL D C LHGG+C D VAGY+C C + G
Sbjct: 726 RGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEG 785
Query: 391 RDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSVMAGSPIQ 450
C ++ C+ H C +C + +YVC CP G G C T SP Q
Sbjct: 786 AHCELERDECRAHPCRNGGSC----RNLPGAYVCRCPAGFVGVHC--ETEVDACDSSPCQ 839
Score = 120 bits (300), Expect = 1e-26
Identities = 55/155 (35%), Positives = 72/155 (46%), Gaps = 3/155 (1%)
Query: 1054 CRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPD 1113
C C PCLH G+C+D + C C G+EG CE D C + PC G +
Sbjct: 751 CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLP 810
Query: 1114 GRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVP 1173
G + CRCP GF G C V + + S C G CE G A C C E G C+
Sbjct: 811 GAYVCRCPAGFVGVHCETEVDACDSS---PCQHGGRCESGGGAYLCVCPESFFGYHCETV 867
Query: 1174 TLPCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
+ PC ++PC G C A+ G C C ++G+ C
Sbjct: 868 SDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
Score = 111 bits (278), Expect = 4e-24
Identities = 60/159 (37%), Positives = 77/159 (48%), Gaps = 14/159 (8%)
Query: 1059 VC-APSPCLHDGACRDLF----DAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPD 1113
VC A PCL+ G C D ++ C+C G+ G RC V+ C S PC G TH
Sbjct: 271 VCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGI 330
Query: 1114 GRFECRCPPGFGGPRC---RLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRC 1170
F C+CP GFGGP C + P +KEC G C+ + +A C C G G C
Sbjct: 331 NSFRCQCPAGFGGPTCETAQSPCDTKECQ------HGGQCQVENGSAVCVCQAGYTGAAC 384
Query: 1171 QVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
++ C +PCLNGG+C G C+C F G CE
Sbjct: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCE 423
Score = 105 bits (263), Expect = 2e-22
Identities = 71/230 (30%), Positives = 90/230 (39%), Gaps = 78/230 (33%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAH----VDPCHSAPCARGRCHTHPDGR 1115
C+P PCL+ G+C DL + C C ++G RCE D C SAPC G D
Sbjct: 391 CSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQG 450
Query: 1116 FECRCPPGFGGPRCRLPVP-----------------------------------SKECSL 1140
+ C CP GF G CR VP + C++
Sbjct: 451 YVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNM 510
Query: 1141 NVTCLDG-------------------------SPCE------GGSPAAN-----CSCLEG 1164
N C DG SPC+ GGS A+ C C G
Sbjct: 511 NTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRG 570
Query: 1165 LAGQRCQV--PTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAK 1212
G+ C+ P L C + PC NGGTC+ AGG C C RF+G+ CE+ K
Sbjct: 571 FHGKHCEKARPHL-CSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGK 619
Score = 90.9 bits (224), Expect = 7e-18
Identities = 57/206 (27%), Positives = 70/206 (33%), Gaps = 57/206 (27%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
CA PC + G C + C C PG+ G CE PC +PC G D F C
Sbjct: 623 CASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCH 682
Query: 1120 CPPGFGGPRCR------------------------------------LPVPSK------- 1136
C G+ G RC+ L PS+
Sbjct: 683 CQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPH 742
Query: 1137 -------------ECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCL 1183
EC + CL G C+ C C G G C++ C A+PC
Sbjct: 743 GVWSEPPQCLEIDECR-SQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCR 801
Query: 1184 NGGTCRAAGGVSECICNARFSGQFCE 1209
NGG+CR G C C A F G CE
Sbjct: 802 NGGSCRNLPGAYVCRCPAGFVGVHCE 827
Score = 80.5 bits (197), Expect = 1e-14
Identities = 55/215 (25%), Positives = 71/215 (33%), Gaps = 62/215 (28%)
Query: 1054 CRGAPV-CAPSPCLHDGACRDLFDAFACACGPGWEGPR---------------------- 1090
C AP C SPC++ G C D F C C G+ G R
Sbjct: 654 CEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNG 713
Query: 1091 -------------------------CEAH-----------VDPCHSAPCARGRCHTHPDG 1114
C+ H +D C S PC G
Sbjct: 714 TRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVA 773
Query: 1115 RFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPT 1174
+ C C G+ G C L EC + C +G C A C C G G C+
Sbjct: 774 GYLCLCSTGYEGAHCELE--RDECRAH-PCRNGGSCRNLPGAYVCRCPAGFVGVHCETEV 830
Query: 1175 LPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
C+++PC +GG C + GG C+C F G CE
Sbjct: 831 DACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCE 865
Score = 80.1 bits (196), Expect = 1e-14
Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 6/115 (5%)
Query: 1059 VCAPSPCLHDGACRDLFDAFACACGPGWEGPRCE-AHVDPCHSAPCARGRCHTHPDGRFE 1117
+C+ PC + G C++ + C+C + G CE D C S PC G H G+++
Sbjct: 583 LCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYK 642
Query: 1118 CRCPPGFGGPRCRL-PVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQ 1171
C CPPGF G C + P P C++G CE C C G G+RCQ
Sbjct: 643 CDCPPGFSGRHCEIAPSP----CFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQ 693
Score = 74.7 bits (182), Expect = 5e-13
Identities = 33/95 (34%), Positives = 47/95 (49%), Gaps = 3/95 (3%)
Query: 1116 FECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTL 1175
+ C C GF G RC L V EC+ + C +G C G + C C G G C+
Sbjct: 295 YTCSCLSGFTGRRCHLDV--NECA-SQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQS 351
Query: 1176 PCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
PC+ C +GG C+ G + C+C A ++G CE+
Sbjct: 352 PCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEM 386
Score = 65.5 bits (158), Expect = 3e-10
Identities = 30/73 (41%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
Query: 1144 CLDGSPCEG----GSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECIC 1199
CL+G C G+P+ CSCL G G+RC + C + PC NGGTC C C
Sbjct: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQC 337
Query: 1200 NARFSGQFCEVAK 1212
A F G CE A+
Sbjct: 338 PAGFGGPTCETAQ 350
Score = 57.0 bits (136), Expect = 1e-07
Identities = 27/65 (41%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFVCV 869
C+ PC NGGTC N F C CPA F GPTC Q C + C C+ VCV
Sbjct: 315 CASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCV 374
Query: 870 AEATF 874
+A +
Sbjct: 375 CQAGY 379
Score = 52.4 bits (124), Expect = 3e-06
Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 10/83 (12%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC--AQQLWCPGQPCLPPATCEEVPDGFVC 868
C DPCFNGG+C + + C CP F G C A+ C PC TC+E + C
Sbjct: 545 CDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHC 604
Query: 869 VAEATFREGPPAAFSGHNASSGR 891
P F+G + G+
Sbjct: 605 SC--------PYRFTGRHCEIGK 619
Score = 51.6 bits (122), Expect = 5e-06
Identities = 33/96 (34%), Positives = 39/96 (40%), Gaps = 12/96 (12%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQ-----QLWCPGQPCLPPATCEEVP 863
D CSPDPC NGG+C+ ++ C C F G C C PC TC +
Sbjct: 389 DDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDAD 448
Query: 864 DGFVCVAEATF-----REGPPAAFSGHNASSGRLLG 894
G+VC F RE P N GR LG
Sbjct: 449 QGYVCECPEGFMGLDCRERVPDDCECRN--GGRCLG 482
Score = 51.6 bits (122), Expect = 5e-06
Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFV 867
D C+ PC NGGTC + C CP F+G C C PC+ TCE+ F
Sbjct: 621 DSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFF 680
Query: 868 CVAEATF 874
C +A +
Sbjct: 681 CHCQAGY 687
Score = 51.2 bits (121), Expect = 6e-06
Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 10/79 (12%)
Query: 810 MCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC--AQQLWCPGQPCLPPATCEEVPDGFV 867
+CS PC NGGTC ++HC+CP FTG C + C PC TC +
Sbjct: 583 LCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYK 642
Query: 868 CVAEATFREGPPAAFSGHN 886
C P FSG +
Sbjct: 643 CDC--------PPGFSGRH 653
Score = 50.1 bits (118), Expect = 1e-05
Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
+ D C PC NGG+C + C CPA F G C ++ C PC CE
Sbjct: 790 LERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGG 849
Query: 865 GFVCVAEATF 874
++CV +F
Sbjct: 850 AYLCVCPESF 859
Score = 49.7 bits (117), Expect = 2e-05
Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 799 WNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPA 857
W+ C+ D C PC +GG+C + C C + G C ++ C PC
Sbjct: 745 WSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGG 804
Query: 858 TCEEVPDGFVCVAEATF 874
+C +P +VC A F
Sbjct: 805 SCRNLPGAYVCRCPAGF 821
Score = 48.9 bits (115), Expect = 3e-05
Identities = 34/92 (36%), Positives = 43/92 (46%), Gaps = 10/92 (10%)
Query: 31 AGTVPSEPPSACASD-----PCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQ 85
A TV S+P ++ + P Q E G G + P C+ PC +G CVP
Sbjct: 1267 AATVRSQPTASAQLENMEEAPKRVSLALQLPEHGSKDIGNV-PGNCSENPCQNGGTCVP- 1324
Query: 86 GPDPTGFRCYCVPGFQGPRCELDIDECASRPC 117
G D C C PGF+G RCEL + SRPC
Sbjct: 1325 GAD--AHSCDCGPGFKGRRCELACIK-VSRPC 1353
Score = 48.5 bits (114), Expect = 4e-05
Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 11/62 (17%)
Query: 150 CASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLD-----------LDECQSQPCAHGGT 198
C+ PC +GG+C+ G + C C PG+ G RC+L E ++ P GG
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
Query: 199 CH 200
CH
Sbjct: 1371 CH 1372
Score = 46.6 bits (109), Expect = 2e-04
Identities = 65/267 (24%), Positives = 93/267 (34%), Gaps = 44/267 (16%)
Query: 609 CRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCA--------DEIPAATFGLGGAPSSASF 660
C PCV+GG+C D T F C C + G C +E+ AT G A
Sbjct: 661 CFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVA 720
Query: 661 LLQELPGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPGR 720
L G +L+ +R + G+ S + + E R + + G
Sbjct: 721 LYACDRGYSLSAPSRIRVCQPHGVW------SEPPQCLEIDECRSQPCLHGGSCQ----- 769
Query: 721 WDDGLRHLVMLSFGPDQLQDLGQHVHVGGRLLAADSQPWGGPFRGCLQDLRLDGCHLPFF 780
D +L + S G + G H + A GG R L + C F
Sbjct: 770 -DRVAGYLCLCSTGYE-----GAHCELERDECRAHPCRNGGSCRN-LPGAYVCRCPAGFV 822
Query: 781 PLPLDNS-----SQPSELGGR-QSWNLTAGCVS------------EDMCSPDPCFNGGTC 822
+ + S P + GGR +S CV D C PC G C
Sbjct: 823 GVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYC 882
Query: 823 LVTWNDFHCTCPANFTGPTCAQQLWCP 849
L + CTC +TG CA++L+ P
Sbjct: 883 LASNGSHSCTCKVGYTGEDCAKELFPP 909
Score = 45.1 bits (105), Expect = 4e-04
Identities = 17/34 (50%), Positives = 23/34 (67%)
Query: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
+ C P PC++GGSCVDL ++ C CA P +G C
Sbjct: 389 DDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRC 422
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/65 (38%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
Query: 815 PCFNGGTCL---VTWN-DFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
PC NGG C+ VT N + C+C + FTG C + C QPC TC + F C
Sbjct: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQ 336
Query: 870 AEATF 874
A F
Sbjct: 337 CPAGF 341
Score = 43.9 bits (102), Expect = 0.001
Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR 1105
C+ +PC + G C DA +C CGPG++G RCE S PC R
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPCTR 1355
Score = 43.5 bits (101), Expect = 0.001
Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 1/70 (1%)
Query: 807 SEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDG 865
++ C C +GG C V C C A +TG C + C PCL +C ++
Sbjct: 349 AQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGN 408
Query: 866 FVCVAEATFR 875
+ C+ F+
Sbjct: 409 YTCLCAEPFK 418
Score = 42.0 bits (97), Expect = 0.004
Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 18/92 (19%)
Query: 188 CQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRC 247
C PC +GGTC + CDC G G++G CE ++ S PC S
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDC-GPGFKGRRCELACIK-VSRPCTRLFS--------ET 1360
Query: 248 LCWPGYSGELC--------EVDEDECASSPCQ 271
+P + G +C V +D C C+
Sbjct: 1361 KAFPVWEGGVCHHVYKRVYRVHQDICFKESCE 1392
Score = 41.2 bits (95), Expect = 0.006
Identities = 16/35 (45%), Positives = 18/35 (51%)
Query: 1177 CEANPCLNGGTCRAAGGVSECICNARFSGQFCEVA 1211
C NPC NGGTC C C F G+ CE+A
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELA 1345
Score = 40.0 bits (92), Expect = 0.014
Identities = 16/43 (37%), Positives = 21/43 (48%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWC 848
++ C PC NGGTC DF C C A + G C ++ C
Sbjct: 656 IAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDC 698
Score = 40.0 bits (92), Expect = 0.014
Identities = 15/38 (39%), Positives = 21/38 (55%)
Query: 603 CERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
C ++CR PC+HGGSC D + C C+ + G C
Sbjct: 751 CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHC 788
Score = 39.3 bits (90), Expect = 0.025
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 112 CASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPC 155
C+ PC +G TC AD + C C G+ G CE+ + S PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
Score = 37.7 bits (86), Expect = 0.071
Identities = 27/70 (38%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 578 GCLQDVRVDGHLLLPEDLGENVLLGCE-RREQCRPLPCVHGGSCVDLWTHFRCDCARPHR 636
G QD RV G+L L E CE R++CR PC +GGSC +L + C C
Sbjct: 766 GSCQD-RVAGYLCLCSTGYEGA--HCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFV 822
Query: 637 GPTCADEIPA 646
G C E+ A
Sbjct: 823 GVHCETEVDA 832
Score = 37.0 bits (84), Expect = 0.12
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
+C PC +GG+C FRC C GPTC
Sbjct: 314 ECASQPCQNGGTCTHGINSFRCQCPAGFGGPTC 346
Score = 37.0 bits (84), Expect = 0.12
Identities = 16/47 (34%), Positives = 19/47 (40%)
Query: 310 PGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE 356
P D G C+ PC NGG C + C C G+ G CE
Sbjct: 1297 PEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 37.0 bits (84), Expect = 0.12
Identities = 16/43 (37%), Positives = 20/43 (46%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPC 853
CS +PC NGGTC+ + C C F G C +PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
Score = 36.2 bits (82), Expect = 0.21
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 12/62 (19%)
Query: 1138 CSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTL----PC-------EANPCLNGG 1186
CS N C +G C G+ A +C C G G+RC++ + PC +A P GG
Sbjct: 1311 CSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
Query: 1187 TC 1188
C
Sbjct: 1370 VC 1371
Score = 35.8 bits (81), Expect = 0.27
Identities = 13/39 (33%), Positives = 20/39 (51%)
Query: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIP 645
+ C PC +GG+CVD + C+C G C + +P
Sbjct: 431 DACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVP 469
Score = 35.0 bits (79), Expect = 0.46
Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 22/65 (33%)
Query: 265 CASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDEC 324
C+ +PCQ+GG C+ PGA + C C PGF+G C + +
Sbjct: 1311 CSENPCQNGGTCV---------------PGADAHS------CDCGPGFKGRRCELACIK- 1348
Query: 325 ASRPC 329
SRPC
Sbjct: 1349 VSRPC 1353
Score = 33.5 bits (75), Expect = 1.3
Identities = 20/76 (26%), Positives = 28/76 (36%), Gaps = 2/76 (2%)
Query: 362 CLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPL--AATCIPIFESGV 419
C +PC +GGTC + C C + GR C + L P++E GV
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
Query: 420 HSYVCHCPPGTHGPFC 435
+V H C
Sbjct: 1371 CHHVYKRVYRVHQDIC 1386
>gi|116235485 delta-notch-like EGF repeat-containing transmembrane
[Homo sapiens]
Length = 737
Score = 250 bits (639), Expect = 5e-66
Identities = 123/327 (37%), Positives = 169/327 (51%), Gaps = 39/327 (11%)
Query: 33 TVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVP--QGPDPT 90
T PSE +C + GT C+ ++ C +PC + A C+ + D +
Sbjct: 327 TKPSEATFSCTCEEQYVGTFCEEYDA------------CQRKPCQNNASCIDANEKQDGS 374
Query: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC 150
F C C+PG+ G C+ ID C PC +GATC + + C CP GY G CE +VD C
Sbjct: 375 NFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPC 434
Query: 151 ASAPCLHGGSC-LDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCD 209
AS+PC + G+C +DGV F C C+PG+ G C +D C PCAH GTC + ++C
Sbjct: 435 ASSPCQNNGTCYVDGV-HFTCNCSPGFTGPTCAQLIDFCALSPCAH-GTCRSVGTSYKCL 492
Query: 210 CAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSP 269
C GY G +CE E EC SAPC + A+C + + + C+C Y G CE+ +D CA+
Sbjct: 493 C-DPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVS 551
Query: 270 CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPC 329
C +G C L G C C PGF G +C ++++EC S PC
Sbjct: 552 CLNGATC---DSDGLNG------------------TCICAPGFTGEECDIDINECDSNPC 590
Query: 330 LNGGHCQDLPNGFQCHCPDGYAGPTCE 356
+GG C D PNG+ CHCP G+ G CE
Sbjct: 591 HHGGSCLDQPNGYNCHCPHGWVGANCE 617
Score = 223 bits (568), Expect = 9e-58
Identities = 114/347 (32%), Positives = 164/347 (47%), Gaps = 31/347 (8%)
Query: 62 TCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGA 121
TC P E + C C + P F C C + G CE + D C +PC + A
Sbjct: 306 TCVPGESHANDLE-CSGKGKCTTK-PSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNA 362
Query: 122 TCRNLADR-----YECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGY 176
+C + ++ + C C GY G C+ ++D C PC +G +C+ + F C C GY
Sbjct: 363 SCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGY 422
Query: 177 GGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNA 236
G+ C+ +D C S PC + GTC+ F C+C+ G+ G C + + CA +PC H
Sbjct: 423 FGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCS-PGFTGPTCAQLIDFCALSPCAHG- 480
Query: 237 SCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAF 296
+C S++CLC PGY G CE + +EC S+PC + C +
Sbjct: 481 TCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVN--------------- 525
Query: 297 SFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE 356
G+ C C ++G C + D CA+ CLNG C C C G+ G C+
Sbjct: 526 ------GYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECD 579
Query: 357 EDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGH 403
D++EC S+PC HGG+C D GY C CP W G +C + L GH
Sbjct: 580 IDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQWKSGH 626
Score = 215 bits (548), Expect = 2e-55
Identities = 111/311 (35%), Positives = 143/311 (45%), Gaps = 33/311 (10%)
Query: 130 YECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGV-----GSFRCVCAPGYGGTRCQLD 184
+ C C Y G CE E D C PC + SC+D +F CVC PGY G CQ
Sbjct: 334 FSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSK 392
Query: 185 LDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGS 244
+D C PC +G TC ++GF C C GY G+ CE +V CAS+PC++N +C
Sbjct: 393 IDYCILDPCRNGATCISSLSGFTCQCP-EGYFGSACEEKVDPCASSPCQNNGTCYVDGVH 451
Query: 245 FRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGF 304
F C C PG++G C D CA SPC HG C +
Sbjct: 452 FTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVG---------------------TSY 489
Query: 305 LCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLS 364
C C PG+ G C E +EC S PCLN C+DL NG++C C Y G CE D C +
Sbjct: 490 KCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCAN 549
Query: 365 DPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVC 424
CL+G TC C C + G +C + + C + C +C+ + Y C
Sbjct: 550 VSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCL----DQPNGYNC 605
Query: 425 HCPPGTHGPFC 435
HCP G G C
Sbjct: 606 HCPHGWVGANC 616
Score = 156 bits (395), Expect = 1e-37
Identities = 81/201 (40%), Positives = 107/201 (53%), Gaps = 18/201 (8%)
Query: 32 GTVPSEPPSACASDPCAPGTECQATESGGYTC-------GPMEPR---GCATQPCHHGAL 81
G+ E CAS PC C + +TC GP + CA PC HG
Sbjct: 424 GSACEEKVDPCASSPCQNNGTCYV-DGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGT- 481
Query: 82 CVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGV 141
C G T ++C C PG+ G CE + +EC S PC + ATCR+L + YEC C Y G
Sbjct: 482 CRSVG---TSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGT 538
Query: 142 TCEMEVDECASAPCLHGGSC-LDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCH 200
CE+ D CA+ CL+G +C DG+ C+CAPG+ G C +D++EC S PC HGG+C
Sbjct: 539 HCELYKDPCANVSCLNGATCDSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCL 597
Query: 201 DLVNGFRCDCAGTGYEGTHCE 221
D NG+ C C G+ G +CE
Sbjct: 598 DQPNGYNCHCP-HGWVGANCE 617
Score = 116 bits (290), Expect = 2e-25
Identities = 67/219 (30%), Positives = 100/219 (45%), Gaps = 15/219 (6%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
CA SPC H G CR + ++ C C PG+ G CE + C SAPC +EC
Sbjct: 472 CALSPCAH-GTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECV 530
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
C + G C L K+ NV+CL+G+ C+ C C G G+ C + C++
Sbjct: 531 CLAEYKGTHCEL---YKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDS 587
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEV---------AKGLPLPLPFPLLEVAVPAA 1230
NPC +GG+C C C + G CE+ A+ L +P L + + A
Sbjct: 588 NPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQWKSGHMAESL-TNMPRHSLYIIIGAL 646
Query: 1231 CACLLLLLLGLLSGILAARKRRQSEGTYSPSQQEVAGAR 1269
C +L+L+ L+ GI R + +G+ P+ +E R
Sbjct: 647 CVAFILMLIILIVGICRI-SRIEYQGSSRPAYEEFYNCR 684
Score = 107 bits (268), Expect = 6e-23
Identities = 52/149 (34%), Positives = 72/149 (48%), Gaps = 10/149 (6%)
Query: 302 AGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLP-----NGFQCHCPDGYAGPTCE 356
A F C C + G C E D C +PC N C D + F C C GY G C+
Sbjct: 332 ATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQ 390
Query: 357 EDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFE 416
+D C+ DPC +G TC +++G+ C+CPE + G C ++ C C TC +
Sbjct: 391 SKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTC---YV 447
Query: 417 SGVHSYVCHCPPGTHGPFCGQNTTFSVMA 445
GVH + C+C PG GP C Q F ++
Sbjct: 448 DGVH-FTCNCSPGFTGPTCAQLIDFCALS 475
Score = 103 bits (257), Expect = 1e-21
Identities = 57/155 (36%), Positives = 71/155 (45%), Gaps = 8/155 (5%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCA-RGRCHTHPDG-RFE 1117
C PC + C F C C G+ G CE VDPC S+PC G C+ DG F
Sbjct: 396 CILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYV--DGVHFT 453
Query: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
C C PGF GP C + C+L+ C G+ C + C C G G C+ C
Sbjct: 454 CNCSPGFTGPTCAQLIDF--CALS-PCAHGT-CRSVGTSYKCLCDPGYHGLYCEEEYNEC 509
Query: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCEVAK 1212
+ PCLN TCR EC+C A + G CE+ K
Sbjct: 510 LSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYK 544
Score = 82.8 bits (203), Expect = 2e-15
Identities = 55/151 (36%), Positives = 65/151 (43%), Gaps = 38/151 (25%)
Query: 6 PGTPDPQALASVLLLLLWAPALSLLAGTVPSEPPSACASDPCAPGTECQATESGGYTCGP 65
PG ALA +LLLL P S LA VP+ P SA
Sbjct: 9 PGAQLLPALALLLLLLGAGPRGSSLANPVPAAPLSA------------------------ 44
Query: 66 MEPRGCATQPCHHGALCV------PQGPDPTG---FRCYCVPGFQGPRCELDIDECASRP 116
P CA QPC +G +C PQ P P G + C C G G C+L D CAS P
Sbjct: 45 --PGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNP 102
Query: 117 CHHG---ATCRNLADRYECHCPLGYAGVTCE 144
CHHG ++ + +D Y C C GY G CE
Sbjct: 103 CHHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 77.8 bits (190), Expect = 6e-14
Identities = 44/136 (32%), Positives = 59/136 (43%), Gaps = 9/136 (6%)
Query: 1078 FACACGPGWEGPRCEAHVDPCHSAPCARGR----CHTHPDG-RFECRCPPGFGGPRCRLP 1132
F+C C + G CE + D C PC + DG F C C PG+ G C+
Sbjct: 334 FSCTCEEQYVGTFCEEY-DACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSK 392
Query: 1133 VPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAG 1192
+ C L+ C +G+ C C C EG G C+ PC ++PC N GTC G
Sbjct: 393 IDY--CILD-PCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDG 449
Query: 1193 GVSECICNARFSGQFC 1208
C C+ F+G C
Sbjct: 450 VHFTCNCSPGFTGPTC 465
Score = 73.2 bits (178), Expect = 2e-12
Identities = 35/96 (36%), Positives = 47/96 (48%), Gaps = 12/96 (12%)
Query: 265 CASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDEC 324
CA+ PC++GG C R +P A PG + C CP G GA+C + D C
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPG---------YSCTCPAGISGANCQLVADPC 98
Query: 325 ASRPCLNG---GHCQDLPNGFQCHCPDGYAGPTCEE 357
AS PC +G +G+ C C +GY GP CE+
Sbjct: 99 ASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 65.9 bits (159), Expect = 2e-10
Identities = 32/89 (35%), Positives = 43/89 (48%), Gaps = 15/89 (16%)
Query: 324 CASRPCLNGGHCQDLPN------------GFQCHCPDGYAGPTCEEDVDECLSDPCLHGG 371
CA++PC NGG C P G+ C CP G +G C+ D C S+PC HG
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 372 TCSDTVA---GYICRCPETWGGRDCSVQL 397
S + + GY+C C E + G +C L
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCEQAL 136
Score = 63.2 bits (152), Expect = 2e-09
Identities = 40/131 (30%), Positives = 56/131 (42%), Gaps = 12/131 (9%)
Query: 1082 CGPGWEGPRCEAHVDPCHSAPCARGRCHTHP-DGRFECRCPPGFGGPRCRL--PVPSKEC 1138
C PG E+H + + +G+C T P + F C C + G C K C
Sbjct: 307 CVPG------ESHANDLECS--GKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPC 358
Query: 1139 SLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECI 1198
N +C+D + + GS C CL G G+ CQ C +PC NG TC ++ C
Sbjct: 359 QNNASCIDANEKQDGSNFT-CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQ 417
Query: 1199 CNARFSGQFCE 1209
C + G CE
Sbjct: 418 CPEGYFGSACE 428
Score = 60.1 bits (144), Expect = 1e-08
Identities = 40/128 (31%), Positives = 55/128 (42%), Gaps = 23/128 (17%)
Query: 1088 GPRCEAHVDPCHSAPC-ARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLD 1146
GPR + +P +AP A G C P CR GG P P +
Sbjct: 27 GPRGSSLANPVPAAPLSAPGPCAAQP-----CRN----GGVCTSRPEPDPQ--------- 68
Query: 1147 GSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSE---CICNARF 1203
P G P +C+C G++G CQ+ PC +NPC +G ++ S+ CICN +
Sbjct: 69 -HPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGY 127
Query: 1204 SGQFCEVA 1211
G CE A
Sbjct: 128 EGPNCEQA 135
Score = 59.7 bits (143), Expect = 2e-08
Identities = 31/88 (35%), Positives = 39/88 (44%), Gaps = 16/88 (18%)
Query: 150 CASAPCLHGGSCLD------------GVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHG- 196
CA+ PC +GG C G + C C G G CQL D C S PC HG
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 197 --GTCHDLVNGFRCDCAGTGYEGTHCER 222
+ +G+ C C GYEG +CE+
Sbjct: 108 CSSSSSSSSDGYLCIC-NEGYEGPNCEQ 134
Score = 57.4 bits (137), Expect = 9e-08
Identities = 27/64 (42%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D C+ PC N GTC V F C C FTGPTCAQ + +C PC TC V +
Sbjct: 432 DPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPC-AHGTCRSVGTSYK 490
Query: 868 CVAE 871
C+ +
Sbjct: 491 CLCD 494
Score = 56.2 bits (134), Expect = 2e-07
Identities = 31/104 (29%), Positives = 40/104 (38%), Gaps = 17/104 (16%)
Query: 1048 PAPILGCRGAPVCAPSPCLHDGACRDLFD------------AFACACGPGWEGPRCEAHV 1095
P P CA PC + G C + ++C C G G C+
Sbjct: 36 PVPAAPLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVA 95
Query: 1096 DPCHSAPCARGRC----HTHPDGRFECRCPPGFGGPRCRLPVPS 1135
DPC S PC G C + DG + C C G+ GP C +PS
Sbjct: 96 DPCASNPCHHGNCSSSSSSSSDG-YLCICNEGYEGPNCEQALPS 138
Score = 52.0 bits (123), Expect = 4e-06
Identities = 30/103 (29%), Positives = 41/103 (39%), Gaps = 30/103 (29%)
Query: 227 CASAPCEHNASCLE------------GLGSFRCLCWPGYSGELCEVDEDECASSPCQHGG 274
CA+ PC + C G + C C G SG C++ D CAS+PC H G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHH-G 106
Query: 275 RCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADC 317
C S + + G+LC C G+EG +C
Sbjct: 107 NCSSSSSSS-----------------SDGYLCICNEGYEGPNC 132
Score = 50.1 bits (118), Expect = 1e-05
Identities = 27/87 (31%), Positives = 36/87 (41%), Gaps = 16/87 (18%)
Query: 188 CQSQPCAHGGTCHDLVN------------GFRCDCAGTGYEGTHCEREVLECASAPCEH- 234
C +QPC +GG C G+ C C G G +C+ CAS PC H
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPA-GISGANCQLVADPCASNPCHHG 106
Query: 235 --NASCLEGLGSFRCLCWPGYSGELCE 259
++S + C+C GY G CE
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 50.1 bits (118), Expect = 1e-05
Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 2/74 (2%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D C DPC NG TC+ + + F C CP + G C +++ C PC TC F
Sbjct: 394 DYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFT 453
Query: 868 CVAEATFREGPPAA 881
C F GP A
Sbjct: 454 CNCSPGF-TGPTCA 466
Score = 46.2 bits (108), Expect = 2e-04
Identities = 25/88 (28%), Positives = 32/88 (36%), Gaps = 13/88 (14%)
Query: 362 CLSDPCLHGGTCSDTVA------------GYICRCPETWGGRDCSVQLTGCQGHTCPLAA 409
C + PC +GG C+ GY C CP G +C + C + C
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCH-HG 106
Query: 410 TCIPIFESGVHSYVCHCPPGTHGPFCGQ 437
C S Y+C C G GP C Q
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 43.9 bits (102), Expect = 0.001
Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 6/70 (8%)
Query: 805 CVSEDMCSPDPCFNGGTCL-----VTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPAT 858
C D C PC N +C+ ++F C C +TG C ++ +C PC AT
Sbjct: 347 CEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGAT 406
Query: 859 CEEVPDGFVC 868
C GF C
Sbjct: 407 CISSLSGFTC 416
Score = 41.6 bits (96), Expect = 0.005
Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 1/62 (1%)
Query: 808 EDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGF 866
+D C+ C NG TC + C C FTG C + C PC +C + P+G+
Sbjct: 544 KDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGY 603
Query: 867 VC 868
C
Sbjct: 604 NC 605
Score = 39.3 bits (90), Expect = 0.025
Identities = 16/41 (39%), Positives = 22/41 (53%)
Query: 604 ERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
E+ + C PC + G+C HF C+C+ GPTCA I
Sbjct: 429 EKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLI 469
Score = 38.9 bits (89), Expect = 0.032
Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 5/67 (7%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLW---CPGQPCLPPATCEEVPDGFV 867
C PC N TC N + C C A + G C +L+ C CL ATC+
Sbjct: 509 CLSAPCLNAATCRDLVNGYECVCLAEYKGTHC--ELYKDPCANVSCLNGATCDSDGLNGT 566
Query: 868 CVAEATF 874
C+ F
Sbjct: 567 CICAPGF 573
Score = 38.9 bits (89), Expect = 0.032
Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPG 850
C +PC +GG+CL N ++C CP + G C L W G
Sbjct: 585 CDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQWKSG 625
Score = 36.6 bits (83), Expect = 0.16
Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 21/86 (24%)
Query: 811 CSPDPCFNGGTCLVTWND------------FHCTCPANFTGPTCAQQLW---CPGQPCLP 855
C+ PC NGG C + CTCPA +G C QL C PC
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANC--QLVADPCASNPCHH 105
Query: 856 ---PATCEEVPDGFVCVAEATFREGP 878
++ DG++C+ + EGP
Sbjct: 106 GNCSSSSSSSSDGYLCICNEGY-EGP 130
Score = 33.9 bits (76), Expect = 1.0
Identities = 13/33 (39%), Positives = 16/33 (48%)
Query: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
+C PC HGGSC+D + C C G C
Sbjct: 584 ECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANC 616
Score = 33.1 bits (74), Expect = 1.8
Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 7/61 (11%)
Query: 816 CFNGGTCLVTWND--FHCTCPANFTGPTCAQQLWCPGQPCLPPATC---EEVPDG--FVC 868
C G C ++ F CTC + G C + C +PC A+C E DG F C
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTC 378
Query: 869 V 869
V
Sbjct: 379 V 379
Score = 32.3 bits (72), Expect = 3.0
Identities = 14/47 (29%), Positives = 22/47 (46%), Gaps = 5/47 (10%)
Query: 603 CERREQCRPLPCVHGGSCVDL-----WTHFRCDCARPHRGPTCADEI 644
CE + C+ PC + SC+D ++F C C + G C +I
Sbjct: 347 CEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKI 393
Score = 32.3 bits (72), Expect = 3.0
Identities = 14/47 (29%), Positives = 22/47 (46%)
Query: 594 DLGENVLLGCERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
D G + L E +C PC++ +C DL + C C ++G C
Sbjct: 494 DPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHC 540
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 243 bits (621), Expect = 7e-64
Identities = 129/356 (36%), Positives = 171/356 (48%), Gaps = 52/356 (14%)
Query: 59 GGYTCGPMEPRGC--------ATQPCHHGALCVPQGPDPTGF-----RCYCVPGFQGPRC 105
G +TCG + C T+P +C+P + GF C C G+QG C
Sbjct: 200 GHFTCGERGEKVCNPGWKGPYCTEP-----ICLPGCDEQHGFCDKPGECKCRVGWQGRYC 254
Query: 106 ELDIDECASRP-CHHGATCRNLADRYECHCPLGYAGVTCEMEVDECAS-APCLHGGSCLD 163
DEC P C HG TC+ ++C+C G+ G+ C +++ C PC +G +C +
Sbjct: 255 ----DECIRYPGCLHG-TCQQ---PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTN 306
Query: 164 -GVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCER 222
G GS+ C C PGY G C+L +DEC PC +GG+C DL N + C C G+ G CE
Sbjct: 307 TGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCP-PGFYGKICEL 365
Query: 223 EVLECASAPCEHNASCLEGL-GSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSD 281
+ CA PC + C + G + C C GYSG CE D C+SSPC +G +C+ D
Sbjct: 366 SAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGD 425
Query: 282 PALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNG 341
+LC C GF G C VD+CAS PC NGG C+D N
Sbjct: 426 ---------------------AYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVND 464
Query: 342 FQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQL 397
F C CP GY G C V C PC +G TC + Y+C C +GG +C L
Sbjct: 465 FSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLL 520
Score = 236 bits (601), Expect = 1e-61
Identities = 126/343 (36%), Positives = 171/343 (49%), Gaps = 41/343 (11%)
Query: 96 CVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAP- 154
C PG++GP C I C C EC C +G+ G C DEC P
Sbjct: 212 CNPGWKGPYCTEPI--CLPGCDEQHGFCDKPG---ECKCRVGWQGRYC----DECIRYPG 262
Query: 155 CLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDEC-QSQPCAHGGTCHDLVNG-FRCDCAG 212
CLHG +C ++C C G+GG C DL+ C +PC +G TC + G + C C
Sbjct: 263 CLHG-TCQQ---PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCR- 317
Query: 213 TGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQH 272
GY G CE + EC +PC++ SC + S+ C C PG+ G++CE+ CA PC +
Sbjct: 318 PGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFN 377
Query: 273 GGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNG 332
GGRC D G+ C CP G+ G +C ++D C+S PC NG
Sbjct: 378 GGRCSDSPD--------------------GGYSCRCPVGYSGFNCEKKIDYCSSSPCSNG 417
Query: 333 GHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRD 392
C DL + + C C G++G C+++VD+C S PC +GGTC D V + C CP + GR+
Sbjct: 418 AKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRN 477
Query: 393 CSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
CS ++ C+ C ATC E G H YVC C G GP C
Sbjct: 478 CSAPVSRCEHAPCHNGATC---HERG-HRYVCECARGYGGPNC 516
Score = 220 bits (561), Expect = 6e-57
Identities = 116/330 (35%), Positives = 158/330 (47%), Gaps = 48/330 (14%)
Query: 42 CASDPCAPGTECQATESGGYTCGPMEPR-----------GCATQP-CHHGALCVPQGPDP 89
C C PG + E G+ P E + C P C HG P
Sbjct: 221 CTEPICLPGCD----EQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQP----- 271
Query: 90 TGFRCYCVPGFQGPRCELDIDECAS-RPCHHGATCRNLAD-RYECHCPLGYAGVTCEMEV 147
++C C G+ G C D++ C +PC +GATC N Y C C GY G TCE+ +
Sbjct: 272 --WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGI 329
Query: 148 DECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNG-F 206
DEC +PC +GGSC D S+ C C PG+ G C+L C PC +GG C D +G +
Sbjct: 330 DECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGY 389
Query: 207 RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECA 266
C C GY G +CE+++ C+S+PC + A C++ ++ C C G+SG C+ + D+CA
Sbjct: 390 SCRCP-VGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCA 448
Query: 267 SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECAS 326
SSPC +GG C GV F C CPPG+ G +C V C
Sbjct: 449 SSPCANGGTCRD--------GVN-------------DFSCTCPPGYTGRNCSAPVSRCEH 487
Query: 327 RPCLNGGHCQDLPNGFQCHCPDGYAGPTCE 356
PC NG C + + + C C GY GP C+
Sbjct: 488 APCHNGATCHERGHRYVCECARGYGGPNCQ 517
Score = 127 bits (319), Expect = 7e-29
Identities = 62/161 (38%), Positives = 81/161 (50%), Gaps = 13/161 (8%)
Query: 42 CASDPCAPGTECQATESGGYTCG-PMEPRG---------CATQPCHHGALCVPQGPDPTG 91
CA PC G C + GGY+C P+ G C++ PC +GA CV G
Sbjct: 370 CADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGD---A 426
Query: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
+ C C GF G C+ ++D+CAS PC +G TCR+ + + C CP GY G C V C
Sbjct: 427 YLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCE 486
Query: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQP 192
APC +G +C + + C CA GYGG CQ L E P
Sbjct: 487 HAPCHNGATCHERGHRYVCECARGYGGPNCQFLLPELPPGP 527
Score = 121 bits (304), Expect = 4e-27
Identities = 77/247 (31%), Positives = 100/247 (40%), Gaps = 49/247 (19%)
Query: 1056 GAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTHPDG 1114
G C PSPC + G+C DL ++++C C PG+ G CE C PC GRC PDG
Sbjct: 328 GIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDG 387
Query: 1115 RFECRCPPGFGGPRCRLPV---PSKECSLNVTCLD------------------------- 1146
+ CRCP G+ G C + S CS C+D
Sbjct: 388 GYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDC 447
Query: 1147 -GSPCEGGSPAA------NCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECIC 1199
SPC G +C+C G G+ C P CE PC NG TC G C C
Sbjct: 448 ASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCEC 507
Query: 1200 NARFSGQFCE--VAKGLPLPLPFPLLE-----------VAVPAACACLLLLLLGLLSGIL 1246
+ G C+ + + P P L E VAV A +L+LLLG + ++
Sbjct: 508 ARGYGGPNCQFLLPELPPGPAVVDLTEKLEGQGGPFPWVAVCAGVILVLMLLLGCAAVVV 567
Query: 1247 AARKRRQ 1253
R R Q
Sbjct: 568 CVRLRLQ 574
Score = 99.8 bits (247), Expect = 2e-20
Identities = 51/154 (33%), Positives = 70/154 (45%), Gaps = 17/154 (11%)
Query: 1064 PCLHDGACRDLFD-AFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPP 1122
PC + C + ++ C+C PG+ G CE +D C +PC G T + + C CPP
Sbjct: 297 PCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPP 356
Query: 1123 GFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAA-------NCSCLEGLAGQRCQVPTL 1175
GF G C L +TC DG PC G + +C C G +G C+
Sbjct: 357 GFYGKICELSA--------MTCADG-PCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKID 407
Query: 1176 PCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
C ++PC NG C G C C A FSG+ C+
Sbjct: 408 YCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCD 441
Score = 82.8 bits (203), Expect = 2e-15
Identities = 42/126 (33%), Positives = 56/126 (44%), Gaps = 16/126 (12%)
Query: 42 CASDPCAPGTEC-----------QATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPT 90
C+S PC+ G +C QA SG + ++ CA+ PC +G C D
Sbjct: 409 CSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDD--CASSPCANGGTCRDGVND-- 464
Query: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC 150
F C C PG+ G C + C PCH+GATC RY C C GY G C+ + E
Sbjct: 465 -FSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLPEL 523
Query: 151 ASAPCL 156
P +
Sbjct: 524 PPGPAV 529
Score = 80.9 bits (198), Expect = 7e-15
Identities = 47/156 (30%), Positives = 67/156 (42%), Gaps = 15/156 (9%)
Query: 1058 PVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAP-CARGRCHTHPDGRF 1116
P+C P G C + C C GW+G C D C P C G C +
Sbjct: 224 PICLPGCDEQHGFCDKPGE---CKCRVGWQGRYC----DECIRYPGCLHGTCQQP----W 272
Query: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEG-GSPAANCSCLEGLAGQRCQVPTL 1175
+C C G+GG C + C+ + C +G+ C G + CSC G G C++
Sbjct: 273 QCNCQEGWGGLFCNQDL--NYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGID 330
Query: 1176 PCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVA 1211
C+ +PC NGG+C C C F G+ CE++
Sbjct: 331 ECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELS 366
Score = 61.6 bits (148), Expect = 5e-09
Identities = 44/132 (33%), Positives = 53/132 (40%), Gaps = 14/132 (10%)
Query: 759 WGGPFRGCLQDLRLDGCHLPFFP-LPLDNSSQPSELGGRQSWNLTAGC-VSEDMCSPDPC 816
WGG F C QDL H P N+ Q S + A C + D C P PC
Sbjct: 280 WGGLF--CNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPC 337
Query: 817 FNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPD-GFVCVAEATF 874
NGG+C N + CTCP F G C + C PC C + PD G+ C
Sbjct: 338 KNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRC---- 393
Query: 875 REGPPAAFSGHN 886
P +SG N
Sbjct: 394 ----PVGYSGFN 401
Score = 60.8 bits (146), Expect = 8e-09
Identities = 34/93 (36%), Positives = 42/93 (45%), Gaps = 7/93 (7%)
Query: 783 PLDNSSQPSELGGRQSWNLTAGCVSE------DMCSPDPCFNGGTCLVTWNDFHCTCPAN 836
P N ++ +LG AG D C+ PC NGGTC NDF CTCP
Sbjct: 413 PCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPG 472
Query: 837 FTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVC 868
+TG C+ + C PC ATC E +VC
Sbjct: 473 YTGRNCSAPVSRCEHAPCHNGATCHERGHRYVC 505
Score = 56.2 bits (134), Expect = 2e-07
Identities = 33/120 (27%), Positives = 54/120 (45%), Gaps = 12/120 (10%)
Query: 763 FRGCLQDLRLDGCHLPFFPLPLDNSSQPSELGGRQSWNLTAGC------VSEDMCSPDPC 816
+ G +L +D C P P N ++L S G +S C+ PC
Sbjct: 320 YTGATCELGIDECD----PSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPC 375
Query: 817 FNGGTCLVTWND-FHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCVAEATF 874
FNGG C + + + C CP ++G C +++ +C PC A C ++ D ++C +A F
Sbjct: 376 FNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGF 435
Score = 49.7 bits (117), Expect = 2e-05
Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 9/82 (10%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D CS PC NG C+ + + C C A F+G C + C PC TC + + F
Sbjct: 407 DYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFS 466
Query: 868 CVAEATFREGPPAAFSGHNASS 889
C P ++G N S+
Sbjct: 467 CTC--------PPGYTGRNCSA 480
Score = 39.3 bits (90), Expect = 0.025
Identities = 27/98 (27%), Positives = 36/98 (36%), Gaps = 20/98 (20%)
Query: 346 CPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCS--VQLTGCQGH 403
C G+ GP C E + CL G C C+C W GR C ++ GC
Sbjct: 212 CNPGWKGPYCTEPI--CLPGCDEQHGFCDKPGE---CKCRVGWQGRYCDECIRYPGCLHG 266
Query: 404 TCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTF 441
TC + C+C G G FC Q+ +
Sbjct: 267 TCQ-------------QPWQCNCQEGWGGLFCNQDLNY 291
Score = 38.1 bits (87), Expect = 0.055
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
Query: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIPAAT 648
++C P PC +GGSC DL + C C G C E+ A T
Sbjct: 330 DECDPSPCKNGGSCTDLENSYSCTCPPGFYGKIC--ELSAMT 369
Score = 35.8 bits (81), Expect = 0.27
Identities = 13/38 (34%), Positives = 21/38 (55%)
Query: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIP 645
+C PC +G +C + + C+CAR + GP C +P
Sbjct: 484 RCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLP 521
Score = 35.4 bits (80), Expect = 0.35
Identities = 15/43 (34%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 603 CERR-EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
CE++ + C PC +G CVDL + C C G C D +
Sbjct: 402 CEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNV 444
Score = 34.7 bits (78), Expect = 0.60
Identities = 31/108 (28%), Positives = 39/108 (36%), Gaps = 35/108 (32%)
Query: 594 DLGENVLLGCERR----------EQCRPLPCVHGGSCVDLWTHFRCDC------------ 631
DLG+ L C+ + C PC +GG+C D F C C
Sbjct: 422 DLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAP 481
Query: 632 ------ARPHRGPTCADE----IPAATFGLGGAPSSASFLLQEL-PGP 668
A H G TC + + G GG + FLL EL PGP
Sbjct: 482 VSRCEHAPCHNGATCHERGHRYVCECARGYGG--PNCQFLLPELPPGP 527
Score = 34.7 bits (78), Expect = 0.60
Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 5/46 (10%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPP 856
C PC NG TC + + C C + GP C L P LPP
Sbjct: 485 CEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLL-----PELPP 525
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 231 bits (589), Expect = 3e-60
Identities = 107/248 (43%), Positives = 136/248 (54%), Gaps = 22/248 (8%)
Query: 111 ECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRC 170
EC PCH+ TC+ L Y C CPLGY G+ CE ++DEC+ PCL+ G C D VG F C
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1255
Query: 171 VCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASA 230
C GY G RC+ +++EC S PC + G C D V G+RC C G+ G HCE EV EC S
Sbjct: 1256 ECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCV-KGFVGLHCETEVNECQSN 1314
Query: 231 PCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQA 290
PC +NA C + +G F C C PG+ G C + DEC S PC++G C
Sbjct: 1315 PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKD------------ 1362
Query: 291 AFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGY 350
GA SFR C C GF G+ C + ++EC S PC N C D N + C C G+
Sbjct: 1363 ---GANSFR------CLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGF 1413
Query: 351 AGPTCEED 358
+G CE +
Sbjct: 1414 SGKRCETE 1421
Score = 223 bits (568), Expect = 9e-58
Identities = 97/250 (38%), Positives = 136/250 (54%), Gaps = 25/250 (10%)
Query: 71 CATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRY 130
C PCH+ C G G+ C C G+ G +CE DIDEC+ PC + C++L +
Sbjct: 1197 CFFNPCHNSGTCQQLG---RGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEF 1253
Query: 131 ECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQS 190
C CP GY G CE ++EC+S+PCL+ G C+DGV +RC C G+ G C+ +++ECQS
Sbjct: 1254 ICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQS 1313
Query: 191 QPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCW 250
PC + C D V GF C C G+ GT C + V EC S PC++ A+C +G SFRCLC
Sbjct: 1314 NPCLNNAVCEDQVGGFLCKCP-PGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCA 1372
Query: 251 PGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPP 310
G++G CE++ +EC S+PC++ C+ + + C C P
Sbjct: 1373 AGFTGSHCELNINECQSNPCRNQATCVDELN---------------------SYSCKCQP 1411
Query: 311 GFEGADCGVE 320
GF G C E
Sbjct: 1412 GFSGKRCETE 1421
Score = 201 bits (511), Expect = 4e-51
Identities = 101/259 (38%), Positives = 134/259 (51%), Gaps = 28/259 (10%)
Query: 187 ECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFR 246
EC PC + GTC L G+ C C GY G CE ++ EC+ PC +N C + +G F
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCP-LGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFI 1254
Query: 247 CLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLC 306
C C GY+G+ CE + +EC+SSPC + G C+ GV AG+ C
Sbjct: 1255 CECPSGYTGQRCEENINECSSSPCLNKGICVD--------GV-------------AGYRC 1293
Query: 307 HCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDP 366
C GF G C EV+EC S PCLN C+D GF C CP G+ G C ++VDECLS P
Sbjct: 1294 TCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQP 1353
Query: 367 CLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHC 426
C +G TC D + C C + G C + + CQ + C ATC+ ++SY C C
Sbjct: 1354 CKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCV----DELNSYSCKC 1409
Query: 427 PPGTHGPFC--GQNTTFSV 443
PG G C Q+T F++
Sbjct: 1410 QPGFSGKRCETEQSTGFNL 1428
Score = 148 bits (374), Expect = 3e-35
Identities = 107/363 (29%), Positives = 151/363 (41%), Gaps = 58/363 (15%)
Query: 97 VPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLG---YAGVTCEMEVDECASA 153
+ +Q +L+ C S RN++D + C G Y+G+ + C S
Sbjct: 1020 IGSYQDEEGQLECKLCPSGMYTEYIHSRNISD-CKAQCKQGTYSYSGL------ETCESC 1072
Query: 154 PCLHGGSCLDGVGSFRCVCAPGYGGT--RCQLDLDECQSQPCAHGG-------TCHDLV- 203
P G+ GS C+ P T R +++ C PC G CH
Sbjct: 1073 PL---GTYQPKFGSRSCLSCPENTSTVKRGAVNISAC-GVPCPEGKFSRSGLMPCHPCPR 1128
Query: 204 -----NGFRCDCAGTGYEGTHC---EREVLECASAPCEHNASCLEGLGSFRCLCWPGYSG 255
N + C + GT R + EC+S +A+ E + L
Sbjct: 1129 DYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSAA-EESVVPPASLGHIKKRH 1187
Query: 256 ELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGA 315
E+ EC +PC + G C Q G++C CP G+ G
Sbjct: 1188 EISSQVFHECFFNPCHNSGTCQQLG---------------------RGYVCLCPLGYTGL 1226
Query: 316 DCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSD 375
C ++DEC+ PCLN G C+DL F C CP GY G CEE+++EC S PCL+ G C D
Sbjct: 1227 KCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVD 1286
Query: 376 TVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
VAGY C C + + G C ++ CQ + C A C E V ++C CPPG G C
Sbjct: 1287 GVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVC----EDQVGGFLCKCPPGFLGTRC 1342
Query: 436 GQN 438
G+N
Sbjct: 1343 GKN 1345
Score = 117 bits (294), Expect = 5e-26
Identities = 59/161 (36%), Positives = 77/161 (47%), Gaps = 3/161 (1%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C+ SPCL+ G C D + C C G+ G CE V+ C S PC G F C+
Sbjct: 1273 CSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCK 1332
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
CPPGF G RC V EC L+ C +G+ C+ G+ + C C G G C++ C++
Sbjct: 1333 CPPGFLGTRCGKNV--DEC-LSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQS 1389
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGLPLPLPF 1220
NPC N TC C C FSG+ CE + L F
Sbjct: 1390 NPCRNQATCVDELNSYSCKCQPGFSGKRCETEQSTGFNLDF 1430
Score = 104 bits (259), Expect = 6e-22
Identities = 50/149 (33%), Positives = 67/149 (44%), Gaps = 3/149 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C +PC + G C+ L + C C G+ G +CE +D C PC G F C
Sbjct: 1197 CFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICE 1256
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
CP G+ G RC + ECS + CL+ C G C+C++G G C+ C++
Sbjct: 1257 CPSGYTGQRCEENI--NECS-SSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQS 1313
Query: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFC 1208
NPCLN C G C C F G C
Sbjct: 1314 NPCLNNAVCEDQVGGFLCKCPPGFLGTRC 1342
Score = 68.2 bits (165), Expect = 5e-11
Identities = 40/108 (37%), Positives = 55/108 (50%), Gaps = 16/108 (14%)
Query: 116 PCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPG 175
PC +G C+ C CP G+ G CE + PCL+GG C V ++C C PG
Sbjct: 3475 PCQNGGICQR---PNACSCPEGWMGRLCEEPI---CILPCLNGGRC---VAPYQCDCPPG 3525
Query: 176 YGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCERE 223
+ G+RC + CQS PC +GG C V RC C + + G +C R+
Sbjct: 3526 WTGSRCHTAV--CQS-PCLNGGKC---VRPNRCHCL-SSWTGHNCSRK 3566
Score = 66.6 bits (161), Expect = 1e-10
Identities = 39/118 (33%), Positives = 52/118 (44%), Gaps = 8/118 (6%)
Query: 1092 EAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCE 1151
E +PCH++ G C G + C CP G+ G +C + ECS + CL+ C+
Sbjct: 1196 ECFFNPCHNS----GTCQQLGRG-YVCLCPLGYTGLKCETDID--ECS-PLPCLNNGVCK 1247
Query: 1152 GGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
C C G GQRC+ C ++PCLN G C C C F G CE
Sbjct: 1248 DLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCE 1305
Score = 65.5 bits (158), Expect = 3e-10
Identities = 37/115 (32%), Positives = 46/115 (40%), Gaps = 32/115 (27%)
Query: 32 GTVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTG 91
GT + C S PC G C+ GA
Sbjct: 1339 GTRCGKNVDECLSQPCKNGATCK-----------------------DGA---------NS 1366
Query: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME 146
FRC C GF G CEL+I+EC S PC + ATC + + Y C C G++G CE E
Sbjct: 1367 FRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421
Score = 64.3 bits (155), Expect = 7e-10
Identities = 43/110 (39%), Positives = 50/110 (45%), Gaps = 19/110 (17%)
Query: 328 PCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPET 387
PC NGG CQ PN C CP+G+ G CEE + C+ PCL+GG C VA Y C CP
Sbjct: 3475 PCQNGGICQR-PNA--CSCPEGWMGRLCEEPI--CIL-PCLNGGRC---VAPYQCDCPPG 3525
Query: 388 WGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437
W G C + CQ C C V CHC G C +
Sbjct: 3526 WTGSRCHTAV--CQS-PCLNGGKC-------VRPNRCHCLSSWTGHNCSR 3565
Score = 61.2 bits (147), Expect = 6e-09
Identities = 41/125 (32%), Positives = 52/125 (41%), Gaps = 36/125 (28%)
Query: 231 PCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQA 290
PC++ C C C G+ G LCE + PC +GGRC+
Sbjct: 3475 PCQNGGICQRPNA---CSCPEGWMGRLCE---EPICILPCLNGGRCV------------- 3515
Query: 291 AFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGY 350
A + C CPPG+ G+ C V C S PCLNGG C PN +CHC +
Sbjct: 3516 -----------APYQCDCPPGWTGSRCHTAV--CQS-PCLNGGKCV-RPN--RCHCLSSW 3558
Query: 351 AGPTC 355
G C
Sbjct: 3559 TGHNC 3563
Score = 57.0 bits (136), Expect = 1e-07
Identities = 37/116 (31%), Positives = 47/116 (40%), Gaps = 21/116 (18%)
Query: 1058 PVCAPS---PCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDG 1114
P+C PC + G C+ AC+C GW G CE +P PC G P
Sbjct: 3466 PICRAVCRFPCQNGGICQR---PNACSCPEGWMGRLCE---EPICILPCLNGGRCVAP-- 3517
Query: 1115 RFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRC 1170
++C CPPG+ G RC V CL+G C + C CL G C
Sbjct: 3518 -YQCDCPPGWTGSRCHTAV------CQSPCLNGGKCVRPN---RCHCLSSWTGHNC 3563
Score = 54.3 bits (129), Expect = 7e-07
Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D CSP PC N G C +F C CP+ +TG C + + C PCL C + G+
Sbjct: 1233 DECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYR 1292
Query: 868 CVAEATF 874
C F
Sbjct: 1293 CTCVKGF 1299
Score = 54.3 bits (129), Expect = 7e-07
Identities = 107/459 (23%), Positives = 154/459 (33%), Gaps = 87/459 (18%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D C PC NG TC N F C C A FTG C + C PC ATC + + +
Sbjct: 1347 DECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYS 1406
Query: 868 CVAEATF--REGPPAAFSGHNAS---SG----RLLGGLSLAFRTRDSEAWLLRAAAGALE 918
C + F + +G N SG +L G+ + W ++++
Sbjct: 1407 CKCQPGFSGKRCETEQSTGFNLDFEVSGIYGYVMLDGMLPSLHALTCTFW-MKSSDDMNY 1465
Query: 919 G--VWLAVRNGSLAGGVRGGHGLPGAVLPIPG-------PRVADGAWHRVRLAMERPAAT 969
G + AV NGS + + G VL + G P V DG WH + + +
Sbjct: 1466 GTPISYAVDNGSDNTLLLTDYN--GWVLYVNGREKITNCPSVNDGRWHHIAITW---TSA 1520
Query: 970 TSRWLLWLD------GAATPVAL---RGLASDLGFLQGPGAVRILLAENFTGCLGRVALG 1020
W +++D GA V L G A LG Q AE+F G + ++ L
Sbjct: 1521 NGIWKVYIDGKLSDGGAGLSVGLPIPGGGALVLGQEQDKKGEGFSPAESFVGSISQLNLW 1580
Query: 1021 GLPLPLARPRPGAAPGARE----HFASWPGTPAPILG----------CRGAP-------- 1058
L + + A E + +WP + I+G C P
Sbjct: 1581 DYVLSPQQVKSLATSCPEELSKGNVLAWPDFLSGIVGKVKIDSKSIFCSDCPRLGGSVPH 1640
Query: 1059 VCAPSPCLHDGACRDLFDAFACACGPG----------------WEGPRCEAHVDPCHSAP 1102
+ S L G+ +LF C PG W P C P
Sbjct: 1641 LRTASEDLKPGSKVNLF------CDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPP 1694
Query: 1103 CARGRCHTHPD----GRFECRCPPGF---GGPRCRLPVPSKECSLNVTCLDGSPCEGGSP 1155
H+ D +C G+ G R ++ +CLD C GS
Sbjct: 1695 PLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSD 1754
Query: 1156 AA-NCSCLEGLAGQRCQ-VPTLPCEANPCLNGGTCRAAG 1192
+ + SCL C VP + C C+A G
Sbjct: 1755 CSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPG 1793
Score = 53.1 bits (126), Expect = 2e-06
Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 7/95 (7%)
Query: 781 PLPLDNSSQPSELGGRQSWNLTAGCVSE------DMCSPDPCFNGGTCLVTWNDFHCTCP 834
PLP N+ +L G +G + + CS PC N G C+ + CTC
Sbjct: 1237 PLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCV 1296
Query: 835 ANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVC 868
F G C ++ C PCL A CE+ GF+C
Sbjct: 1297 KGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLC 1331
Score = 52.4 bits (124), Expect = 3e-06
Identities = 36/107 (33%), Positives = 46/107 (42%), Gaps = 18/107 (16%)
Query: 1102 PCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSC 1161
PC G P+ C CP G+ G C P+ C L CL+G C C C
Sbjct: 3475 PCQNGGICQRPNA---CSCPEGWMGRLCEEPI----CIL--PCLNGGRCVA---PYQCDC 3522
Query: 1162 LEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
G G RC T C++ PCLNGG C + C C + ++G C
Sbjct: 3523 PPGWTGSRCH--TAVCQS-PCLNGGKCVRP---NRCHCLSSWTGHNC 3563
Score = 50.4 bits (119), Expect = 1e-05
Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
C +PC N C F C CP F G C + + C QPC ATC++ + F C+
Sbjct: 1311 CQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCL 1370
Query: 870 AEATF 874
A F
Sbjct: 1371 CAAGF 1375
Score = 47.0 bits (110), Expect = 1e-04
Identities = 20/59 (33%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVC 868
C +PC N GTC + C CP +TG C + C PCL C+++ F+C
Sbjct: 1197 CFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1255
Score = 41.6 bits (96), Expect = 0.005
Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
Query: 601 LGCERR-EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
L CE ++C PLPC++ G C DL F C+C + G C + I
Sbjct: 1226 LKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENI 1270
Score = 41.2 bits (95), Expect = 0.006
Identities = 43/144 (29%), Positives = 55/144 (38%), Gaps = 14/144 (9%)
Query: 1081 ACG-PGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCP----PGFGGPRCRLPVPS 1135
ACG P EG + + PCH PC R + F CP F G R
Sbjct: 1105 ACGVPCPEGKFSRSGLMPCH--PCPRDYYQPNAGKAFCLACPFYGTTPFAGSRS-----I 1157
Query: 1136 KECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVS 1195
ECS + + E P A+ ++ QV C NPC N GTC+ G
Sbjct: 1158 TECSSFSSTFSAAE-ESVVPPASLGHIKKRHEISSQV-FHECFFNPCHNSGTCQQLGRGY 1215
Query: 1196 ECICNARFSGQFCEVAKGLPLPLP 1219
C+C ++G CE PLP
Sbjct: 1216 VCLCPLGYTGLKCETDIDECSPLP 1239
Score = 40.8 bits (94), Expect = 0.008
Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 19/103 (18%)
Query: 46 PCAPGTECQATESGGYTCGPM-----EPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGF 100
PC G CQ + G M EP PC +G CV ++C C PG+
Sbjct: 3475 PCQNGGICQRPNACSCPEGWMGRLCEEP--ICILPCLNGGRCVAP------YQCDCPPGW 3526
Query: 101 QGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTC 143
G RC + C S PC +G C CHC + G C
Sbjct: 3527 TGSRCHTAV--CQS-PCLNGGKC---VRPNRCHCLSSWTGHNC 3563
Score = 40.8 bits (94), Expect = 0.008
Identities = 24/66 (36%), Positives = 30/66 (45%), Gaps = 9/66 (13%)
Query: 1149 PCEGGSPAAN---CSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSG 1205
PC+ G CSC EG G+ C+ P PCLNGG C A +C C ++G
Sbjct: 3475 PCQNGGICQRPNACSCPEGWMGRLCEEPIC---ILPCLNGGRCVAP---YQCDCPPGWTG 3528
Query: 1206 QFCEVA 1211
C A
Sbjct: 3529 SRCHTA 3534
Score = 38.1 bits (87), Expect = 0.055
Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 16/80 (20%)
Query: 815 PCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVPDGFVCVAEATF 874
PC NGG C+ + C CP +TG C + C PCL C P+ C+
Sbjct: 3507 PCLNGGRCVAP---YQCDCPPGWTGSRCHTAV-CQ-SPCLNGGKCVR-PNRCHCL----- 3555
Query: 875 REGPPAAFSGHNASSGRLLG 894
++++GHN S R G
Sbjct: 3556 -----SSWTGHNCSRKRRTG 3570
Score = 36.2 bits (82), Expect = 0.21
Identities = 42/176 (23%), Positives = 58/176 (32%), Gaps = 42/176 (23%)
Query: 89 PTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVD 148
P CY + F+ + + A R H + HC C+ E
Sbjct: 238 PKEEHCYLLHSFE------EFEALARRALHEDLPSGSFIQDDMVHC-----SYLCD-EGK 285
Query: 149 ECASAPCLHGGSCLDGV--GSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF 206
+C C GSC G G F C+C GY G Q + C S GT
Sbjct: 286 DC----CDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPS------GT-------- 327
Query: 207 RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGY--SGELCEV 260
Y+ + C P E++ S C+C GY SG+ CE+
Sbjct: 328 --------YKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCEL 375
Score = 35.0 bits (79), Expect = 0.46
Identities = 16/35 (45%), Positives = 21/35 (60%), Gaps = 1/35 (2%)
Query: 145 MEVDECA-SAPCLHGGSCLDGVGSFRCVCAPGYGG 178
++VDECA + C SCL+ GS+ C C P Y G
Sbjct: 1744 LDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTG 1778
Score = 34.7 bits (78), Expect = 0.60
Identities = 31/106 (29%), Positives = 42/106 (39%), Gaps = 27/106 (25%)
Query: 1107 RCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLA 1166
+C TH G FEC C G+ G + EC+ C G+ GSP SC
Sbjct: 295 KCGTHT-GHFECICEKGYYGKGLQY-----ECT---ACPSGTYKPEGSPGGISSC----- 340
Query: 1167 GQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNA--RFSGQFCEV 1210
+PC P N + + +C+C R SGQ CE+
Sbjct: 341 --------IPC---PDENHTSPPGSTSPEDCVCREGYRASGQTCEL 375
Score = 34.7 bits (78), Expect = 0.60
Identities = 48/209 (22%), Positives = 66/209 (31%), Gaps = 70/209 (33%)
Query: 237 SCLEGLGSFRCLCWPGYSGELC---EVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFP 293
SC E L L WP + + ++D S C P L G V
Sbjct: 1595 SCPEELSKGNVLAWPDFLSGIVGKVKIDSKSIFCSDC-----------PRLGGSVPHLRT 1643
Query: 294 GAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGG-------HCQ--------DL 338
+ + + C PGF+ V+ CLN G HC+ L
Sbjct: 1644 ASEDLKPGSKVNLFCDPGFQLVGNPVQY-------CLNQGQWTQPLPHCERISCGVPPPL 1696
Query: 339 PNGFQC------------HCPDGY------------------AGPTCEEDVDEC-LSDPC 367
NGF C +GY P+C DVDEC + C
Sbjct: 1697 ENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCL-DVDECAVGSDC 1755
Query: 368 LHGGTCSDTVAGYICRCPE--TWGGRDCS 394
+C + YIC C T G++C+
Sbjct: 1756 SEHASCLNVDGSYICSCVPPYTGDGKNCA 1784
Score = 33.9 bits (76), Expect = 1.0
Identities = 14/41 (34%), Positives = 20/41 (48%)
Query: 604 ERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
E +C PC++ G CVD +RC C + G C E+
Sbjct: 1268 ENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEV 1308
Score = 33.9 bits (76), Expect = 1.0
Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 223 EVLECA-SAPCEHNASCLEGLGSFRCLCWPGYSGE 256
+V ECA + C +ASCL GS+ C C P Y+G+
Sbjct: 1745 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGD 1779
Score = 33.1 bits (74), Expect = 1.8
Identities = 17/39 (43%), Positives = 20/39 (51%), Gaps = 2/39 (5%)
Query: 103 PRCELDIDECA-SRPCHHGATCRNLADRYECHCPLGYAG 140
P C LD+DECA C A+C N+ Y C C Y G
Sbjct: 1741 PSC-LDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTG 1778
Score = 32.7 bits (73), Expect = 2.3
Identities = 41/161 (25%), Positives = 49/161 (30%), Gaps = 41/161 (25%)
Query: 222 REVLECASAPCEHNASCLEGLGSFRCLCWPGY-----SGELCEVDEDECASSPCQHGGRC 276
RE+ + AS P E + L F L SG + D C S C G C
Sbjct: 229 RELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQDDMVHC-SYLCDEGKDC 287
Query: 277 LQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASR--------- 327
R G H F C C G+ G E C S
Sbjct: 288 CDRMGSCKCG------------THTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPG 335
Query: 328 ------PCLNGGHCQDLPNGF----QCHCPDGY--AGPTCE 356
PC + H P G C C +GY +G TCE
Sbjct: 336 GISSCIPCPDENHTS--PPGSTSPEDCVCREGYRASGQTCE 374
Score = 32.0 bits (71), Expect = 3.9
Identities = 13/34 (38%), Positives = 17/34 (50%)
Query: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
++C PC +G +C D FRC CA G C
Sbjct: 1347 DECLSQPCKNGATCKDGANSFRCLCAAGFTGSHC 1380
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 220 bits (561), Expect = 6e-57
Identities = 129/374 (34%), Positives = 165/374 (44%), Gaps = 49/374 (13%)
Query: 69 RGCATQPCHHGA-LCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLA 127
R C + H G +C P G C+PG+ G C+ I C S C A
Sbjct: 186 RLCKKRNDHFGHYVCQPDG------NLSCLPGWTGEYCQQPI--CLSGCHEQNGYCSKPA 237
Query: 128 DRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGS--FRCVCAPGYGGTRCQLDL 185
EC C G+ G C C+ C G S ++C C G+GG C DL
Sbjct: 238 ---ECLCRPGWQGRLCN---------ECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDL 285
Query: 186 DEC-QSQPCAHGGTCHDL-VNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLG 243
+ C PC +G TC + + C C GY G CE E+ EC S PC + SC +
Sbjct: 286 NYCTHHSPCKNGATCSNSGQRSYTCTCR-PGYTGVDCELELSECDSNPCRNGGSCKDQED 344
Query: 244 SFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAG 303
+ CLC PGY G CE CA SPC +GG C +R+ A Y
Sbjct: 345 GYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYA----------------- 387
Query: 304 FLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECL 363
C CPP F G++C +VD C S PC NGG C + C C G+ G CE V +C
Sbjct: 388 --CECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCA 445
Query: 364 SDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQ--LTGCQGHTCPLAATCIPIFESGVHS 421
+PC HGGTC D G +C CP + GR C V+ + C C ATC + +
Sbjct: 446 RNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYT--DLSTDT 503
Query: 422 YVCHCPPGTHGPFC 435
+VC+CP G G C
Sbjct: 504 FVCNCPYGFVGSRC 517
Score = 201 bits (510), Expect = 5e-51
Identities = 118/347 (34%), Positives = 164/347 (47%), Gaps = 45/347 (12%)
Query: 45 DPCAPGTECQATESGGYTCGPMEPRGCA---TQPCHHGALCVPQGPDPTGF-----RCYC 96
D C+ + + G Y C P C T +C+ + G+ C C
Sbjct: 182 DNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLC 241
Query: 97 VPGFQGPRCELDIDECASRP-CHHGATCRNLADRYECHCPLGYAGVTCEMEVDECAS-AP 154
PG+QG C +EC C HG TC + ++C C G+ G+ C+ +++ C +P
Sbjct: 242 RPGWQGRLC----NECIPHNGCRHG-TC---STPWQCTCDEGWGGLFCDQDLNYCTHHSP 293
Query: 155 CLHGGSCLD-GVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGT 213
C +G +C + G S+ C C PGY G C+L+L EC S PC +GG+C D +G+ C C
Sbjct: 294 CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCP-P 352
Query: 214 GYEGTHCEREVLECASAPCEHNASCLEGL--GSFRCLCWPGYSGELCEVDEDECASSPCQ 271
GY G HCE L CA +PC + SC E ++ C C P ++G CE D C S+PC
Sbjct: 353 GYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCA 412
Query: 272 HGGRCLQRSDPALYGGVQAAFPGAFSFRHAA------------------GFLCHCPPGFE 313
+GG+CL R P+ + F G + H + G +C CP GF
Sbjct: 413 NGGQCLNRG-PSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFS 471
Query: 314 GADCGVE--VDECASRPCLNGGHCQ-DLPNG-FQCHCPDGYAGPTCE 356
G C V +D CAS PC N C DL F C+CP G+ G CE
Sbjct: 472 GRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 182 bits (462), Expect = 2e-45
Identities = 111/367 (30%), Positives = 159/367 (43%), Gaps = 59/367 (16%)
Query: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECH------CPLGYAGVTCEM 145
+R C + G C C R H G Y C C G+ G C+
Sbjct: 171 YRVICSDNYYGDNCSR---LCKKRNDHFG--------HYVCQPDGNLSCLPGWTGEYCQQ 219
Query: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNG 205
+ C S G C C+C PG+ G C +EC GTC
Sbjct: 220 PI--CLSGCHEQNGYCSKPA---ECLCRPGWQGRLC----NECIPHNGCRHGTCS---TP 267
Query: 206 FRCDCAGTGYEGTHCEREVLECAS-APCEHNASCLE-GLGSFRCLCWPGYSGELCEVDED 263
++C C G+ G C++++ C +PC++ A+C G S+ C C PGY+G CE++
Sbjct: 268 WQCTC-DEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELS 326
Query: 264 ECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDE 323
EC S+PC++GG C + D G+ C CPPG+ G C
Sbjct: 327 ECDSNPCRNGGSCKDQED---------------------GYHCLCPPGYYGLHCEHSTLS 365
Query: 324 CASRPCLNGGHCQDLPNG--FQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYI 381
CA PC NGG C++ G + C CP + G CE+ VD C S+PC +GG C + +
Sbjct: 366 CADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRM 425
Query: 382 CRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTF 441
CRC + G C + ++ C + C TC + E+G+ +C CP G G C T+
Sbjct: 426 CRCRPGFTGTYCELHVSDCARNPCAHGGTCHDL-ENGL---MCTCPAGFSGRRCEVRTSI 481
Query: 442 SVMAGSP 448
A SP
Sbjct: 482 DACASSP 488
Score = 166 bits (421), Expect = 1e-40
Identities = 85/226 (37%), Positives = 106/226 (46%), Gaps = 39/226 (17%)
Query: 40 SACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPG 99
S C S+PC G C+ E G + C C PG
Sbjct: 326 SECDSNPCRNGGSCKDQEDG--------------------------------YHCLCPPG 353
Query: 100 FQGPRCELDIDECASRPCHHGATC--RNLADRYECHCPLGYAGVTCEMEVDECASAPCLH 157
+ G CE CA PC +G +C RN Y C CP + G CE +VD C S PC +
Sbjct: 354 YYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCAN 413
Query: 158 GGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEG 217
GG CL+ S C C PG+ GT C+L + +C PCAHGGTCHDL NG C C G+ G
Sbjct: 414 GGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCP-AGFSG 472
Query: 218 THCE--REVLECASAPCEHNASCLEGLG--SFRCLCWPGYSGELCE 259
CE + CAS+PC + A+C L +F C C G+ G CE
Sbjct: 473 RRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 121 bits (304), Expect = 4e-27
Identities = 75/206 (36%), Positives = 101/206 (49%), Gaps = 15/206 (7%)
Query: 1060 CAPSPCLHDGACRDLFDA--FACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRF 1116
CA SPC + G+CR+ +AC C P + G CE VD C S PCA G +C R
Sbjct: 366 CADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRM 425
Query: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTL- 1175
CRC PGF G C L V +C+ N C G C C+C G +G+RC+V T
Sbjct: 426 -CRCRPGFTGTYCELHV--SDCARN-PCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSI 481
Query: 1176 -PCEANPCLNGGTCRAAGGVSECICNA--RFSGQFCEVAKGLPLPLPFPLLEVAVPAACA 1232
C ++PC N TC +CN F G CE GLP P+ + + V A
Sbjct: 482 DACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGLPPSFPWVAVSLGVGLA-- 539
Query: 1233 CLLLLLLGLLS-GILAARKRRQSEGT 1257
+LL+LLG+++ + R RR +G+
Sbjct: 540 -VLLVLLGMVAVAVRQLRLRRPDDGS 564
Score = 114 bits (284), Expect = 8e-25
Identities = 56/153 (36%), Positives = 71/153 (46%), Gaps = 5/153 (3%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDG-RFE 1117
C +PC + G+C+D D + C C PG+ G CE C +PC G C G +
Sbjct: 328 CDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYA 387
Query: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
C CPP F G C V C+ N C +G C P+ C C G G C++ C
Sbjct: 388 CECPPNFTGSNCEKKVD--RCTSN-PCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDC 444
Query: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
NPC +GGTC C C A FSG+ CEV
Sbjct: 445 ARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEV 477
Score = 99.0 bits (245), Expect = 3e-20
Identities = 52/152 (34%), Positives = 69/152 (45%), Gaps = 8/152 (5%)
Query: 1063 SPCLHDGACRDLFD-AFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFECRC 1120
SPC + C + ++ C C PG+ G CE + C S PC G C DG + C C
Sbjct: 292 SPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDG-YHCLC 350
Query: 1121 PPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAAN--CSCLEGLAGQRCQVPTLPCE 1178
PPG+ G C S C+ + C +G C + AN C C G C+ C
Sbjct: 351 PPGYYGLHCEHSTLS--CA-DSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCT 407
Query: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
+NPC NGG C G C C F+G +CE+
Sbjct: 408 SNPCANGGQCLNRGPSRMCRCRPGFTGTYCEL 439
Score = 77.4 bits (189), Expect = 8e-14
Identities = 47/126 (37%), Positives = 55/126 (43%), Gaps = 16/126 (12%)
Query: 42 CASDPCAPGTEC-QATESGGYTCGP--------MEPRGCATQPCHHGALCVPQGPDPTGF 92
C S+PCA G +C S C P + CA PC HG C G
Sbjct: 406 CTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDL---ENGL 462
Query: 93 RCYCVPGFQGPRCEL--DIDECASRPCHHGATCRN--LADRYECHCPLGYAGVTCEMEVD 148
C C GF G RCE+ ID CAS PC + ATC D + C+CP G+ G CE V
Sbjct: 463 MCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVG 522
Query: 149 ECASAP 154
S P
Sbjct: 523 LPPSFP 528
Score = 72.0 bits (175), Expect = 3e-12
Identities = 48/175 (27%), Positives = 67/175 (38%), Gaps = 45/175 (25%)
Query: 1073 DLFDAFAC------ACGPGWEGPRCEAHV--DPCHSAPCARGRCHTHPDGRFECRCPPGF 1124
D F + C +C PGW G C+ + CH G C EC C PG+
Sbjct: 193 DHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQ---NGYCSKPA----ECLCRPGW 245
Query: 1125 GGPRCRLPVPSKEC-------SLNVTCLDG----------------SPCEGGSPAAN--- 1158
G C +P C TC +G SPC+ G+ +N
Sbjct: 246 QGRLCNECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQ 305
Query: 1159 ----CSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
C+C G G C++ C++NPC NGG+C+ C+C + G CE
Sbjct: 306 RSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCE 360
Score = 52.4 bits (124), Expect = 3e-06
Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 9/77 (11%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLW-CPGQPCLPPATCEEVPDGFV 867
D C+ +PC NGG CL C C FTG C + C PC TC ++ +G +
Sbjct: 404 DRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLM 463
Query: 868 CVAEATFREGPPAAFSG 884
C PA FSG
Sbjct: 464 CTC--------PAGFSG 472
Score = 51.2 bits (121), Expect = 6e-06
Identities = 41/131 (31%), Positives = 49/131 (37%), Gaps = 11/131 (8%)
Query: 759 WGGPFRGCLQDLRLDGCHLPFFP-LPLDNSSQPSELGGRQSWNLTAGCVSE-DMCSPDPC 816
WGG F C QDL H P NS Q S + C E C +PC
Sbjct: 276 WGGLF--CDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPC 333
Query: 817 FNGGTCLVTWNDFHCTCPANFTGPTCAQQ-LWCPGQPCLPPATCEEVPDGFVCVAEATFR 875
NGG+C + +HC CP + G C L C PC +C E G E
Sbjct: 334 RNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACEC--- 390
Query: 876 EGPPAAFSGHN 886
P F+G N
Sbjct: 391 ---PPNFTGSN 398
Score = 50.8 bits (120), Expect = 8e-06
Identities = 26/63 (41%), Positives = 32/63 (50%), Gaps = 5/63 (7%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL---WCPGQPCLPPATC--EEVPDG 865
C+ +PC +GGTC N CTCPA F+G C + C PC ATC + D
Sbjct: 444 CARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDT 503
Query: 866 FVC 868
FVC
Sbjct: 504 FVC 506
Score = 45.8 bits (107), Expect = 3e-04
Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 3/52 (5%)
Query: 811 CSPDPCFNGGTCLVTWN--DFHCTCPANFTGPTCAQQL-WCPGQPCLPPATC 859
C+ PCFNGG+C ++ C CP NFTG C +++ C PC C
Sbjct: 366 CADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQC 417
Score = 37.7 bits (86), Expect = 0.071
Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 2/38 (5%)
Query: 807 SEDMCSPDPCFNGGTCL--VTWNDFHCTCPANFTGPTC 842
S D C+ PCFN TC ++ + F C CP F G C
Sbjct: 480 SIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 517
Score = 32.7 bits (73), Expect = 2.3
Identities = 13/32 (40%), Positives = 14/32 (43%)
Query: 609 CRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
C PC HGG+C DL C C G C
Sbjct: 444 CARNPCAHGGTCHDLENGLMCTCPAGFSGRRC 475
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 214 bits (546), Expect = 3e-55
Identities = 190/702 (27%), Positives = 278/702 (39%), Gaps = 104/702 (14%)
Query: 260 VDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAG-FLCHCPPGFEGADCG 318
VD D C PCQ+GG CL+R + + + P FLC C PG+ G+ C
Sbjct: 3801 VDHDSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCE 3860
Query: 319 VEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVA 378
+++DEC PC +GG C +L GF C CPDG+ G CE D++ECL PC +G C +
Sbjct: 3861 IDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPG 3920
Query: 379 GYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438
+ C C + G+ C + C+ + C +C +SGV SY CHCP G G C N
Sbjct: 3921 SFNCVCKTGYTGKMCESSVNYCECNPCFNGGSC----QSGVDSYYCHCPFGVFGKHCELN 3976
Query: 439 T-TFSVMAGSPIQASVPAGGPLGLALRFRTTLPAGTLATR--NDTKESLELALVAATLQA 495
+ F ++ + P + ++F T L N T + E + +
Sbjct: 3977 SYGFEELSYMEFPSLDPNNN--YIYVKFATIKSHALLLYNYDNQTGDRAEFLALEIAEER 4034
Query: 496 TLWSYSTTVLVLRLPDL-ALNDGHWHQVEVVLHLATLELRLWHEGC-----PARLCVASG 549
+SY+ +L + ++DGH+H V+ A + L + C P V++
Sbjct: 4035 LRFSYNLGSGTYKLTTMKKVSDGHFH--TVIARRAGMAASLTVDSCSENQEPGYCTVSNV 4092
Query: 550 PVALASTASATP---LPAGISSAQ--------LGDATFAGCLQDVRVDGHLLLPED--LG 596
V+ T P GI S + + F GC+ + V+G L P
Sbjct: 4093 AVSDDWTLDVQPNRVTVGGIRSLEPILQRRGHVESHDFVGCIMEFAVNGRPLEPSQALAA 4152
Query: 597 ENVLLGCERRE-QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI-PAATFGLGGA 654
+ +L C R E C PC HGG+C+D W+ +C C G C + P L G
Sbjct: 4153 QGILDQCPRLEGACTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCEKSVTPDTALSLEGK 4212
Query: 655 ----------PSSASFLLQELPGPNL------TVSFLLRTRESAGLLLQFANDS------ 692
L Q L G L ++ RTR G+L+ S
Sbjct: 4213 GRLDYHMSQNEKREYLLRQSLRGAMLEPFGVNSLEVKFRTRSENGVLIHIQESSNYTTVK 4272
Query: 693 -AAGLTVFLSE----GRIRAEVPGSPAVVLPGRWDDGL--RHLVMLSFGPDQL------- 738
G F S+ G++ +P V G W L ++ D++
Sbjct: 4273 IKNGKVYFTSDAGIAGKVERNIP--EVYVADGHWHTFLIGKNGTATVLSVDRIYNRDIIH 4330
Query: 739 --QDLG----QHVHVGG---RLLAADSQPWGGPFRGCLQDLRLDGCHLPF---FPLPLDN 786
QD G + +GG D+Q G F GC+ + G LPF L +
Sbjct: 4331 PTQDFGGLDVLTISLGGIPPNQAHRDAQTAG--FDGCIASMWYGGESLPFSGKHSLASIS 4388
Query: 787 SSQPSELGGRQSWNLTAG-----------------CVSEDMCSPDPCFNGGTCLV-TWND 828
+ PS G + N+ A CV C+ PC NGG+C +
Sbjct: 4389 KTDPSVKIGCRGPNICASNPCWGDLLCINQWYAYRCVPPGDCASHPCQNGGSCEPGLHSG 4448
Query: 829 FHCTCPANFTGPTCAQQLWCPGQPCLPPATCEE-VPDGFVCV 869
F C+CP + TG TC + C G C C+ P G VCV
Sbjct: 4449 FTCSCPDSHTGRTCEMVVACLGVLCPQGKVCKAGSPAGHVCV 4490
Score = 144 bits (364), Expect = 4e-34
Identities = 73/205 (35%), Positives = 98/205 (47%), Gaps = 45/205 (21%)
Query: 136 LGYAGVTCE-MEVDECASAPCLHGGSCL----------------------DGVGSFRCVC 172
L +GV E ++ D C PC +GGSCL + + F C C
Sbjct: 3791 LRQSGVKVESVDHDSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKC 3850
Query: 173 APGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPC 232
PGY G+ C++D+DEC PC GGTCH+LV GF C C G+ G CER++ EC +PC
Sbjct: 3851 LPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPD-GFTGRACERDINECLQSPC 3909
Query: 233 EHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAF 292
++ A C GSF C+C GY+G++CE + C +PC +GG C D
Sbjct: 3910 KNGAICQNFPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVD----------- 3958
Query: 293 PGAFSFRHAAGFLCHCPPGFEGADC 317
+ CHCP G G C
Sbjct: 3959 ----------SYYCHCPFGVFGKHC 3973
Score = 143 bits (361), Expect = 9e-34
Identities = 58/130 (44%), Positives = 77/130 (59%), Gaps = 1/130 (0%)
Query: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
F C C+PG+ G CE+DIDEC PCH G TC NL + C CP G+ G CE +++EC
Sbjct: 3846 FLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECL 3905
Query: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA 211
+PC +G C + GSF CVC GY G C+ ++ C+ PC +GG+C V+ + C C
Sbjct: 3906 QSPCKNGAICQNFPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCP 3965
Query: 212 GTGYEGTHCE 221
G G HCE
Sbjct: 3966 -FGVFGKHCE 3974
Score = 129 bits (323), Expect = 2e-29
Identities = 64/177 (36%), Positives = 86/177 (48%), Gaps = 23/177 (12%)
Query: 107 LDIDECASRPCHHGATC-RNLA---------------------DRYECHCPLGYAGVTCE 144
+D D C PC +G +C R LA + C C GYAG CE
Sbjct: 3801 VDHDSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCE 3860
Query: 145 MEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVN 204
+++DEC +PC GG+C + VG F C C G+ G C+ D++EC PC +G C +
Sbjct: 3861 IDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPG 3920
Query: 205 GFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVD 261
F C C TGY G CE V C PC + SC G+ S+ C C G G+ CE++
Sbjct: 3921 SFNCVCK-TGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVFGKHCELN 3976
Score = 108 bits (270), Expect = 3e-23
Identities = 49/114 (42%), Positives = 58/114 (50%), Gaps = 3/114 (2%)
Query: 71 CATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRY 130
C PCH G C GF C C GF G CE DI+EC PC +GA C+N +
Sbjct: 3866 CLPSPCHSGGTCHNL---VGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGSF 3922
Query: 131 ECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLD 184
C C GY G CE V+ C PC +GGSC GV S+ C C G G C+L+
Sbjct: 3923 NCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVFGKHCELN 3976
Score = 99.8 bits (247), Expect = 2e-20
Identities = 55/174 (31%), Positives = 74/174 (42%), Gaps = 27/174 (15%)
Query: 1060 CAPSPCLHDGAC----------------------RDLFDAFACACGPGWEGPRCEAHVDP 1097
C PC + G+C + F C C PG+ G CE +D
Sbjct: 3806 CVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCEIDIDE 3865
Query: 1098 CHSAPC-ARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPA 1156
C +PC + G CH G F C CP GF G C + EC L C +G+ C+ +
Sbjct: 3866 CLPSPCHSGGTCHNLVGG-FSCSCPDGFTGRACERDI--NEC-LQSPCKNGAICQNFPGS 3921
Query: 1157 ANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
NC C G G+ C+ CE NPC NGG+C++ C C G+ CE+
Sbjct: 3922 FNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVFGKHCEL 3975
Score = 93.2 bits (230), Expect = 1e-18
Identities = 105/406 (25%), Positives = 150/406 (36%), Gaps = 54/406 (13%)
Query: 808 EDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVPDGFV 867
E C+ PC +GGTC+ W+ C C TG C + + P G +
Sbjct: 4163 EGACTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCEKSV-------TPDTALSLEGKGRL 4215
Query: 868 CVAEATFREGPPAAFSGHNASSGRLL-----GGLSLAFRTRDSEAWLLRAAAGALEGVWL 922
+ + + + G +L L + FRTR L+ + +
Sbjct: 4216 ---DYHMSQNEKREYLLRQSLRGAMLEPFGVNSLEVKFRTRSENGVLIHIQESS-NYTTV 4271
Query: 923 AVRNGSLAGGVRGGHGLPGAV-LPIPGPRVADGAWHRVRLAMERPAATTSRWLLWLDGAA 981
++NG + G+ G V IP VADG WH + A S ++
Sbjct: 4272 KIKNGKVY--FTSDAGIAGKVERNIPEVYVADGHWHTFLIGKNGTATVLSVDRIYNRDII 4329
Query: 982 TPV----ALRGLASDLGFLQGPGAVRILLAENFTGCLGRVALGGLPLPLARPRPGAAPGA 1037
P L L LG + A R F GC+ + GG LP +
Sbjct: 4330 HPTQDFGGLDVLTISLGGIPPNQAHRDAQTAGFDGCIASMWYGGESLPFS---------G 4380
Query: 1038 REHFASWPGT-PAPILGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVD 1096
+ AS T P+ +GCRG +CA +PC D C + + A+ C PG C +H
Sbjct: 4381 KHSLASISKTDPSVKIGCRGPNICASNPCWGDLLCINQWYAYRCV-PPG----DCASH-- 4433
Query: 1097 PCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPA 1156
PC + G C F C CP G C + V L V C G C+ GSPA
Sbjct: 4434 PCQNG----GSCEPGLHSGFTCSCPDSHTGRTCEMVV----ACLGVLCPQGKVCKAGSPA 4485
Query: 1157 ANCSCLEGLAGQRCQVPTLPCEANPCLNG--GTCRAAGGVSECICN 1200
+ L Q + +LP A P + G T A +S +CN
Sbjct: 4486 GHVCVL----SQGPEEISLPLWAVPAIVGSCATVLALLVLSLILCN 4527
Score = 61.2 bits (147), Expect = 6e-09
Identities = 81/329 (24%), Positives = 105/329 (31%), Gaps = 71/329 (21%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
C PC NG C F+C C +TG C + +C PC +C+ D + C
Sbjct: 3904 CLQSPCKNGAICQNFPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCH 3963
Query: 870 AEATFREGPPAAFSGHNASSGRLLGGLS---------------LAFRTRDSEAWLL---- 910
P F H + LS + F T S A LL
Sbjct: 3964 C-------PFGVFGKHCELNSYGFEELSYMEFPSLDPNNNYIYVKFATIKSHALLLYNYD 4016
Query: 911 RAAAGALEGVWLAVRNGSLAGGVRGGHGLPGAVLPIPGPRVADGAWHRV---RLAM---- 963
E + L + L G G +V+DG +H V R M
Sbjct: 4017 NQTGDRAEFLALEIAEERLRFSYNLGSGTYKLTTM---KKVSDGHFHTVIARRAGMAASL 4073
Query: 964 --------ERPA-------ATTSRWLLWLDGAATPVALRGLASDLGFLQGPGAVRILLAE 1008
+ P A + W L D V + G+ S LQ G V +
Sbjct: 4074 TVDSCSENQEPGYCTVSNVAVSDDWTL--DVQPNRVTVGGIRSLEPILQRRGHVE---SH 4128
Query: 1009 NFTGCLGRVALGGLPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHD 1068
+F GC+ A+ G PL P A A+ P R C SPC H
Sbjct: 4129 DFVGCIMEFAVNGRPL-----EPSQALAAQGILDQCP---------RLEGACTRSPCQHG 4174
Query: 1069 GACRDLFDAFACACGPGWEGPRCEAHVDP 1097
G C D + C C G G CE V P
Sbjct: 4175 GTCMDYWSWQQCHCKEGLTGKYCEKSVTP 4203
Score = 58.5 bits (140), Expect = 4e-08
Identities = 26/67 (38%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
D C P PC +GGTC F C+CP FTG C + + C PC A C+ P F
Sbjct: 3864 DECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGSFN 3923
Query: 868 CVAEATF 874
CV + +
Sbjct: 3924 CVCKTGY 3930
Score = 53.1 bits (126), Expect = 2e-06
Identities = 33/98 (33%), Positives = 41/98 (41%), Gaps = 17/98 (17%)
Query: 68 PRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCR-NL 126
P CA+ PC LC+ Q + CVP +CAS PC +G +C L
Sbjct: 4401 PNICASNPCWGDLLCINQW-----YAYRCVPP----------GDCASHPCQNGGSCEPGL 4445
Query: 127 ADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDG 164
+ C CP + G TCEM V C C G C G
Sbjct: 4446 HSGFTCSCPDSHTGRTCEMVV-ACLGVLCPQGKVCKAG 4482
Score = 49.3 bits (116), Expect = 2e-05
Identities = 30/89 (33%), Positives = 37/89 (41%), Gaps = 14/89 (15%)
Query: 112 CASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGS-FRC 170
CAS PC C N Y C P +CAS PC +GGSC G+ S F C
Sbjct: 4404 CASNPCWGDLLCINQWYAYRCVPP------------GDCASHPCQNGGSCEPGLHSGFTC 4451
Query: 171 VCAPGYGGTRCQLDLDECQSQPCAHGGTC 199
C + G C++ + C C G C
Sbjct: 4452 SCPDSHTGRTCEM-VVACLGVLCPQGKVC 4479
Score = 48.9 bits (115), Expect = 3e-05
Identities = 29/86 (33%), Positives = 38/86 (44%), Gaps = 6/86 (6%)
Query: 39 PSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVP 98
P+ CAS+PC C + Y C P P CA+ PC +G C P +GF C C
Sbjct: 4401 PNICASNPCWGDLLC-INQWYAYRCVP--PGDCASHPCQNGGSCEP--GLHSGFTCSCPD 4455
Query: 99 GFQGPRCELDIDECASRPCHHGATCR 124
G CE+ + C C G C+
Sbjct: 4456 SHTGRTCEM-VVACLGVLCPQGKVCK 4480
Score = 48.1 bits (113), Expect = 5e-05
Identities = 36/124 (29%), Positives = 47/124 (37%), Gaps = 34/124 (27%)
Query: 227 CASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYG 286
CAS PC + C+ ++RC V +CAS PCQ+GG C +P L+
Sbjct: 4404 CASNPCWGDLLCINQWYAYRC------------VPPGDCASHPCQNGGSC----EPGLH- 4446
Query: 287 GVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQ-DLPNGFQCH 345
+GF C CP G C + V C C G C+ P G C
Sbjct: 4447 ---------------SGFTCSCPDSHTGRTCEMVV-ACLGVLCPQGKVCKAGSPAGHVCV 4490
Query: 346 CPDG 349
G
Sbjct: 4491 LSQG 4494
Score = 41.6 bits (96), Expect = 0.005
Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 15/90 (16%)
Query: 188 CQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGS-FR 246
C S PC C + +RC G +CAS PC++ SC GL S F
Sbjct: 4404 CASNPCWGDLLCINQWYAYRCVPPG-------------DCASHPCQNGGSCEPGLHSGFT 4450
Query: 247 CLCWPGYSGELCEVDEDECASSPCQHGGRC 276
C C ++G CE+ C C G C
Sbjct: 4451 CSCPDSHTGRTCEM-VVACLGVLCPQGKVC 4479
Score = 40.4 bits (93), Expect = 0.011
Identities = 19/47 (40%), Positives = 21/47 (44%), Gaps = 3/47 (6%)
Query: 101 QGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEV 147
Q PR E C PC HG TC + +CHC G G CE V
Sbjct: 4158 QCPRLE---GACTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCEKSV 4201
Score = 38.1 bits (87), Expect = 0.055
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 188 CQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREV 224
C PC HGGTC D + +C C G G +CE+ V
Sbjct: 4166 CTRSPCQHGGTCMDYWSWQQCHCK-EGLTGKYCEKSV 4201
Score = 35.8 bits (81), Expect = 0.27
Identities = 24/70 (34%), Positives = 27/70 (38%), Gaps = 9/70 (12%)
Query: 38 PPSACASDPCAPGTECQATESGGYTCGPMEP---RGCATQPCHHGALCVPQGP-----DP 89
PP CAS PC G C+ G+TC + R C G LC PQG P
Sbjct: 4426 PPGDCASHPCQNGGSCEPGLHSGFTCSCPDSHTGRTCEMVVACLGVLC-PQGKVCKAGSP 4484
Query: 90 TGFRCYCVPG 99
G C G
Sbjct: 4485 AGHVCVLSQG 4494
Score = 35.4 bits (80), Expect = 0.35
Identities = 13/33 (39%), Positives = 18/33 (54%)
Query: 150 CASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQ 182
C +PC HGG+C+D +C C G G C+
Sbjct: 4166 CTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCE 4198
Score = 35.0 bits (79), Expect = 0.46
Identities = 13/40 (32%), Positives = 21/40 (52%)
Query: 220 CEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCE 259
C R C +PC+H +C++ +C C G +G+ CE
Sbjct: 4159 CPRLEGACTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCE 4198
Score = 34.7 bits (78), Expect = 0.60
Identities = 12/33 (36%), Positives = 18/33 (54%)
Query: 1177 CEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
C +PC +GGTC +C C +G++CE
Sbjct: 4166 CTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCE 4198
Score = 31.6 bits (70), Expect = 5.1
Identities = 19/60 (31%), Positives = 20/60 (33%), Gaps = 21/60 (35%)
Query: 258 CEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADC 317
C E C SPCQHGG C+ Y Q CHC G G C
Sbjct: 4159 CPRLEGACTRSPCQHGGTCMD------YWSWQQ---------------CHCKEGLTGKYC 4197
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 200 bits (508), Expect = 8e-51
Identities = 149/532 (28%), Positives = 220/532 (41%), Gaps = 103/532 (19%)
Query: 142 TCEMEVD--------ECASAPCLHGGSC-LDGVGSFRCVCAPGYGGTRCQLDLDECQSQP 192
TC+ VD C S PC + G+C D V +RC C G+ G C + + C S P
Sbjct: 906 TCQGPVDVNILAKCNPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNP 965
Query: 193 CAHGGTCH---DLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLC 249
C HGGTCH +GF C CA G+EG +CE V +C CE+N++C++G+ ++ CLC
Sbjct: 966 CKHGGTCHLKEGEEDGFWCICAD-GFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLC 1024
Query: 250 WPGYSGELCEVDEDECAS--SPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCH 307
P Y+GELCE D CA +PCQH +C+ GF C
Sbjct: 1025 PPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPK---------------------GFKCD 1063
Query: 308 CPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE-------EDVD 360
C PG+ G C ++ D+C C NG HC D NG+ C CP+GY+G CE
Sbjct: 1064 CTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTS 1123
Query: 361 ECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVH 420
C + C +G C + IC+C L G QG C +
Sbjct: 1124 PCDNFDCQNGAQCIVRINEPICQC------------LPGYQGEKCEKLVSV--------- 1162
Query: 421 SYVCHCPPGTHGPFCGQNTTFSVMAGSPIQASVPAGGPLGLALRFRTTLPAGTLATRNDT 480
F + + + S + L+ T +G L + D
Sbjct: 1163 ------------NFINKESYLQI-------PSAKVRPQTNITLQIATDEDSGILLYKGD- 1202
Query: 481 KESLELALVAATLQATLWSYSTTVLVLRLPDLALNDGHWHQVEVVLHLATLELRLWHEGC 540
K+ + + L ++A+ + S + + +NDG++H VE++ +L L + G
Sbjct: 1203 KDHIAVELYRGRVRASYDTGSHPASAIYSVE-TINDGNFHIVELLALDQSLSLSV-DGGN 1260
Query: 541 PARLCVASGPVAL--ASTASATPLPAGISSAQLGDA------TFAGCLQDVRVDGHL--- 589
P + S L S +P + A L A +F GC++++ ++ L
Sbjct: 1261 PKIITNLSKQSTLNFDSPLYVGGMPGKSNVASLRQAPGQNGTSFHGCIRNLYINSELQDF 1320
Query: 590 -LLPEDLGENVLLGCERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
+P G +L GC E C C HG F C+C GP C
Sbjct: 1321 QKVPMQTG--ILPGC---EPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLC 1367
Score = 171 bits (432), Expect = 5e-42
Identities = 83/237 (35%), Positives = 111/237 (46%), Gaps = 20/237 (8%)
Query: 42 CASDPCAPGTECQATESGGYTCG-PMEPRG---------CATQPCHHGALCVPQGPDPTG 91
C S+PC C + Y C P +G C + PC HG C + + G
Sbjct: 922 CLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDG 981
Query: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
F C C GF+G CE+++D+C C + +TC + + Y C CP Y G CE ++D CA
Sbjct: 982 FWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCA 1041
Query: 152 S--APCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCD 209
PC H C+ F+C C PGY G C +D D+CQ C +G C D VNG+ C
Sbjct: 1042 QDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYTCI 1101
Query: 210 CAGTGYEGTHCE-------REVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCE 259
C GY G CE C + C++ A C+ + C C PGY GE CE
Sbjct: 1102 CP-EGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCLPGYQGEKCE 1157
Score = 99.4 bits (246), Expect = 2e-20
Identities = 53/165 (32%), Positives = 65/165 (39%), Gaps = 4/165 (2%)
Query: 1060 CAPSPCLHDGACR---DLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRF 1116
C +PC H G C D F C C G+EG CE +VD C C +
Sbjct: 961 CISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNY 1020
Query: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP 1176
C CPP + G C + LN C S C C C G G+ C +
Sbjct: 1021 TCLCPPEYTGELCEEKLDFCAQDLN-PCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDD 1079
Query: 1177 CEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGLPLPLPFP 1221
C+ N C NG C A CIC +SG FCE + + LP P
Sbjct: 1080 CQDNKCKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSP 1124
Score = 76.6 bits (187), Expect = 1e-13
Identities = 47/160 (29%), Positives = 66/160 (41%), Gaps = 14/160 (8%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSA--PCAR-GRCHTHPDGRF 1116
C + C ++ C D + + C C P + G CE +D C PC +C P G F
Sbjct: 1002 CEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKG-F 1060
Query: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVP--- 1173
+C C PG+ G C + +C N C +G+ C C C EG +G C+
Sbjct: 1061 KCDCTPGYVGEHC--DIDFDDCQDN-KCKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPM 1117
Query: 1174 ----TLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
T PC+ C NG C C C + G+ CE
Sbjct: 1118 VLPRTSPCDNFDCQNGAQCIVRINEPICQCLPGYQGEKCE 1157
Score = 75.9 bits (185), Expect = 2e-13
Identities = 42/119 (35%), Positives = 52/119 (43%), Gaps = 7/119 (5%)
Query: 71 CATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDI-DECASRPCHHGATCRNLADR 129
C + C HG C P GF C C G+ GP C+ D C C HG A
Sbjct: 1336 CHKKVCAHGT-CQPSSQ--AGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFS 1392
Query: 130 YECHCPLGYAGVTCEMEVD---ECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDL 185
Y C C G+ GV C+ E D C + C HG L G+G C C+ GY G C ++
Sbjct: 1393 YSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREI 1451
Score = 67.0 bits (162), Expect = 1e-10
Identities = 38/126 (30%), Positives = 54/126 (42%), Gaps = 9/126 (7%)
Query: 103 PRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEV-DECASAPCLHGGSC 161
P CE C + C HG + + C C G+ G C+ D C C+HG
Sbjct: 1331 PGCE----PCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCL 1386
Query: 162 LDGVGSFRCVCAPGYGGTRCQLDLD---ECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGT 218
S+ C C G+GG C + D CQ+ C HG + C+C+ +GY G
Sbjct: 1387 PINAFSYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECS-SGYTGD 1445
Query: 219 HCEREV 224
C+RE+
Sbjct: 1446 SCDREI 1451
Score = 65.9 bits (159), Expect = 2e-10
Identities = 40/125 (32%), Positives = 56/125 (44%), Gaps = 11/125 (8%)
Query: 1089 PRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGS 1148
P CE PCH CA G C F C C G+ GP C + + L C+ G+
Sbjct: 1331 PGCE----PCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLC--DQRTNDPCLGNKCVHGT 1384
Query: 1149 PCEGGSPAANCSCLEGLAGQRCQVPT---LPCEANPCLNGGTCRAAG-GVSECICNARFS 1204
+ + +C CLEG G C PC+A C + G CR +G G C C++ ++
Sbjct: 1385 CLPINAFSYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKH-GKCRLSGLGQPYCECSSGYT 1443
Query: 1205 GQFCE 1209
G C+
Sbjct: 1444 GDSCD 1448
Score = 60.5 bits (145), Expect = 1e-08
Identities = 35/116 (30%), Positives = 45/116 (38%), Gaps = 5/116 (4%)
Query: 148 DECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRC-QLDLDECQSQPCAHGGTCHDLVNGF 206
+ C C HG F C C G+ G C Q D C C HG +
Sbjct: 1334 EPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSY 1393
Query: 207 RCDCAGTGYEGTHCERE---VLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCE 259
C C G+ G C+ E C + C+H L GLG C C GY+G+ C+
Sbjct: 1394 SCKCL-EGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCD 1448
Score = 59.3 bits (142), Expect = 2e-08
Identities = 34/118 (28%), Positives = 47/118 (39%), Gaps = 8/118 (6%)
Query: 322 DECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDV-DECLSDPCLHGGTCSDTVAGY 380
+ C + C +G GF C C +G+ GP C++ D CL + C+HG Y
Sbjct: 1334 EPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSY 1393
Query: 381 ICRCPETWGGRDCSVQ---LTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
C+C E GG C + CQ C + SG+ C C G G C
Sbjct: 1394 SCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRL----SGLGQPYCECSSGYTGDSC 1447
Score = 58.5 bits (140), Expect = 4e-08
Identities = 36/104 (34%), Positives = 46/104 (44%), Gaps = 8/104 (7%)
Query: 1110 THPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQR 1169
T P +F C+ P P S C + TC + P + C+C G GQ
Sbjct: 899 TTPSKKFTCQGPVDVNILAKCNPCLSNPCKNDGTC-NSDPVD----FYRCTCPYGFKGQD 953
Query: 1170 CQVPTLPCEANPCLNGGTCRAAGGVSE---CICNARFSGQFCEV 1210
C VP C +NPC +GGTC G + CIC F G+ CEV
Sbjct: 954 CDVPIHACISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEV 997
Score = 58.2 bits (139), Expect = 5e-08
Identities = 35/117 (29%), Positives = 40/117 (34%), Gaps = 3/117 (2%)
Query: 1056 GAPVCAPSPCLHDGACRDLFDA-FACACGPGWEGPRCEAHV-DPCHSAPCARGRCHTHPD 1113
G C C H G C+ A F C C GW GP C+ DPC C G C
Sbjct: 1332 GCEPCHKKVCAH-GTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINA 1390
Query: 1114 GRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRC 1170
+ C+C G GG C + C G G C C G G C
Sbjct: 1391 FSYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSC 1447
Score = 54.3 bits (129), Expect = 7e-07
Identities = 46/180 (25%), Positives = 63/180 (35%), Gaps = 32/180 (17%)
Query: 186 DECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLE-CASAPCEHNASCLEGLGS 244
+ C + CAHG GF C+C G+ G C++ + C C H S
Sbjct: 1334 EPCHKKVCAHGTCQPSSQAGFTCECQ-EGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFS 1392
Query: 245 FRCLCWPGYSGELCEVDED---ECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHA 301
+ C C G+ G LC+ +ED C + C+H G+C L G Q
Sbjct: 1393 YSCKCLEGHGGVLCDEEEDLFNPCQAIKCKH-GKC------RLSGLGQP----------- 1434
Query: 302 AGFLCHCPPGFEGADCGVEVDECASR------PCLNGGHCQDLPNGFQCHCPDGYAGPTC 355
C C G+ G C E+ R CQ + C G AG C
Sbjct: 1435 ---YCECSSGYTGDSCDREISCRGERIRDYYQKQQGYAACQTTKKVSRLECRGGCAGGQC 1491
Score = 52.4 bits (124), Expect = 3e-06
Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 5/105 (4%)
Query: 302 AGFLCHCPPGFEGADCGVEV-DECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVD 360
AGF C C G+ G C D C C++G + C C +G+ G C+E+ D
Sbjct: 1352 AGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSCKCLEGHGGVLCDEEED 1411
Query: 361 ---ECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQG 402
C + C HG + C C + G C +++ C+G
Sbjct: 1412 LFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREIS-CRG 1455
Score = 49.7 bits (117), Expect = 2e-05
Identities = 57/199 (28%), Positives = 79/199 (39%), Gaps = 32/199 (16%)
Query: 696 LTVFLSEGRIRAEVPGSPAVVLPGRWDDGLRHLVMLSFGPDQLQ--------DLG--QHV 745
LT+ LS R+R +P R DGL+ L +LS + + DL H+
Sbjct: 804 LTLILSYNRLRC---------IPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHL 854
Query: 746 HVGGRLLAAD-SQPWGGPF-RGCLQDLRLDGCHLP---FFPLPLDNSSQPSELGGRQSWN 800
+G L D + W + + ++ + C P L L S+ G N
Sbjct: 855 AIGANPLYCDCNMQWLSDWVKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTCQGPVDVN 914
Query: 801 LTAGCVSEDMCSPDPCFNGGTCLVTWNDFH-CTCPANFTGPTCAQQLW-CPGQPCLPPAT 858
+ A C + C +PC N GTC DF+ CTCP F G C + C PC T
Sbjct: 915 ILAKC---NPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGT 971
Query: 859 C---EEVPDGFVCVAEATF 874
C E DGF C+ F
Sbjct: 972 CHLKEGEEDGFWCICADGF 990
Score = 47.8 bits (112), Expect = 7e-05
Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPG--QPCLPPATCEEV 862
V+ D C + C N TC+ N++ C CP +TG C ++L +C PC + C
Sbjct: 997 VNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCILT 1056
Query: 863 PDGFVC 868
P GF C
Sbjct: 1057 PKGFKC 1062
Score = 47.0 bits (110), Expect = 1e-04
Identities = 36/137 (26%), Positives = 47/137 (34%), Gaps = 25/137 (18%)
Query: 227 CASAPCEHNASCLEGLGSFRCLCWPGYSGELCEV-DEDECASSPCQHGGRCLQRSDPALY 285
C C H F C C G+ G LC+ D C + C HG CL +
Sbjct: 1336 CHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHG-TCLPIN----- 1389
Query: 286 GGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVD---ECASRPCLNGGHCQDLPNGF 342
AFS+ C C G G C E D C + C +G
Sbjct: 1390 ---------AFSYS------CKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQP 1434
Query: 343 QCHCPDGYAGPTCEEDV 359
C C GY G +C+ ++
Sbjct: 1435 YCECSSGYTGDSCDREI 1451
Score = 38.1 bits (87), Expect = 0.055
Identities = 18/64 (28%), Positives = 27/64 (42%), Gaps = 3/64 (4%)
Query: 809 DMCSPD--PCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLW-CPGQPCLPPATCEEVPDG 865
D C+ D PC + C++T F C C + G C C C A C + +G
Sbjct: 1038 DFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNG 1097
Query: 866 FVCV 869
+ C+
Sbjct: 1098 YTCI 1101
Score = 33.9 bits (76), Expect = 1.0
Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 8/86 (9%)
Query: 763 FRGCLQDLRLDGCHLPFFPLPLDNSSQPSELGGRQSWNLTAGCVSE------DMCSPDPC 816
+ G L + +LD C P D+ + G + + T G V E D C + C
Sbjct: 1028 YTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFK--CDCTPGYVGEHCDIDFDDCQDNKC 1085
Query: 817 FNGGTCLVTWNDFHCTCPANFTGPTC 842
NG C N + C CP ++G C
Sbjct: 1086 KNGAHCTDAVNGYTCICPEGYSGLFC 1111
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 198 bits (504), Expect = 2e-50
Identities = 157/581 (27%), Positives = 230/581 (39%), Gaps = 135/581 (23%)
Query: 129 RYECHCPLGYAGVTCEMEVDECASAPCLHGGSCL-DGVGSFRCVCAPGYGGTRCQLDLDE 187
R++C P+ + + + C S+PC + G+C D V +RC C Y G C + ++
Sbjct: 902 RFQCKGPVD---INIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINT 958
Query: 188 CQSQPCAHGGTCH---DLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGS 244
C PC HGGTCH +GF C C G+EG CE +C CE+NA+C++G+ +
Sbjct: 959 CIQNPCQHGGTCHLSDSHKDGFSCSCP-LGFEGQRCEINPDDCEDNDCENNATCVDGINN 1017
Query: 245 FRCLCWPGYSGELCEVDEDECAS--SPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAA 302
+ C+C P Y+GELC+ D C + CQH +C+
Sbjct: 1018 YVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLD---------------------K 1056
Query: 303 GFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEE----- 357
GF C C PG+ G C + D+C + C +G C D NG+ C CP G++GP CE
Sbjct: 1057 GFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMV 1116
Query: 358 --DVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIF 415
C C +G C CRCP + G C +T +
Sbjct: 1117 LLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLIT---------------VN 1161
Query: 416 ESGVHSYVCHCPPGTHGPFCGQNTTFSVMAGSPIQASVPAGGPLGLALRFRTTLPAGTLA 475
G SYV AS ++L+ T G L
Sbjct: 1162 FVGKDSYV-------------------------ELASAKVRPQANISLQVATDKDNGILL 1196
Query: 476 TRNDTKESLELALVAATLQA---TLWSYSTTVLVLRLPDLALNDGHWHQVEVVLHLATLE 532
+ D + L L L ++ +L S TTV + +NDG +H VE+V TL
Sbjct: 1197 YKGD-NDPLALELYQGHVRLVYDSLSSPPTTVYSVE----TVNDGQFHSVELVTLNQTLN 1251
Query: 533 LRLWHEGCPARLCVASGPVALASTA----SATPLPAGISSAQLGD----ATFAGCLQDVR 584
L + +G P L A+ + P G+S+ + G F GC+ +VR
Sbjct: 1252 L-VVDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVR 1310
Query: 585 VDGHL-----LLPEDLGENVLLGCERREQCR----------------------PL----- 612
++ L L P+ LG V GC+ C+ PL
Sbjct: 1311 INNELQDFKALPPQSLG--VSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEA 1368
Query: 613 --PCV----HGGSCVDLWTHFRCDCARPHRGPTCADEIPAA 647
PC+ H G CV T + C CA + G C ++ +A
Sbjct: 1369 RDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDSA 1409
Score = 158 bits (399), Expect = 4e-38
Identities = 79/239 (33%), Positives = 103/239 (43%), Gaps = 20/239 (8%)
Query: 40 SACASDPCAPGTECQATESGGYTCG-PMEPRG---------CATQPCHHGALCVPQGPDP 89
+AC S PC C Y C P +G C PC HG C
Sbjct: 918 NACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHK 977
Query: 90 TGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDE 149
GF C C GF+G RCE++ D+C C + ATC + + Y C CP Y G C+ +D
Sbjct: 978 DGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDH 1037
Query: 150 CASA--PCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFR 207
C C H C+ F C C PGY G C+ D D+C + C HG C D +NG+
Sbjct: 1038 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097
Query: 208 CDCAGTGYEGTHCER-------EVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCE 259
C C G+ G CE + C C++ A C+ C C PG++G CE
Sbjct: 1098 CTCP-QGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
Score = 91.3 bits (225), Expect = 5e-18
Identities = 55/192 (28%), Positives = 76/192 (39%), Gaps = 43/192 (22%)
Query: 1060 CAPSPCLHDGAC-RDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCH---THPDG 1114
C SPC ++G C +D + + CAC ++G C ++ C PC G CH +H DG
Sbjct: 920 CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 979
Query: 1115 RFECRCPPGFGGPRCRL---PVPSKECSLNVTCLDG------------------------ 1147
F C CP GF G RC + +C N TC+DG
Sbjct: 980 -FSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHC 1038
Query: 1148 ----------SPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSEC 1197
+ C +C C+ G +G+ C+ C A+ C +G C C
Sbjct: 1039 VPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTC 1098
Query: 1198 ICNARFSGQFCE 1209
C FSG FCE
Sbjct: 1099 TCPQGFSGPFCE 1110
Score = 89.7 bits (221), Expect = 2e-17
Identities = 106/409 (25%), Positives = 137/409 (33%), Gaps = 68/409 (16%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCE--EVPDGF 866
D C C +G C+ T N + CTCP F+GP C P L + C+ E +G
Sbjct: 1076 DDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHP---PPMVLLQTSPCDQYECQNGA 1132
Query: 867 VCVA---EATFREGPPAAFSGHNASSGRLLGGLSLAFRTRDSEAWLLRAAAGALEGVWLA 923
C+ E T R P F+G +++ F +DS L A + L
Sbjct: 1133 QCIVVQQEPTCR--CPPGFAGPRCEKL-----ITVNFVGKDSYVELASAKVRPQANISLQ 1185
Query: 924 VR-------------NGSLAGGVRGGH---------GLPGAVLPIPGPRVADGAWHRVRL 961
V N LA + GH P V + V DG +H V L
Sbjct: 1186 VATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSVE--TVNDGQFHSVEL 1243
Query: 962 AMERPAATTSRWLLWLDGAATPVALRGLASDLGFLQGPGAVRILLAENFTGCLGRVALGG 1021
L+ V +G LG LQ AV I G L
Sbjct: 1244 VT-------------LNQTLNLVVDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSA 1290
Query: 1022 LPLPLARPRPGAAPGARE-----HFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLF- 1075
L RP G E + P LG +P C G CR +
Sbjct: 1291 LRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGV--SPGCKSCTVCKHGLCRSVEK 1348
Query: 1076 DAFACACGPGWEGPRCEAHV-DPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVP 1134
D+ C C PGW GP C+ DPC C G+C + C+C G+GG C
Sbjct: 1349 DSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKC-VATGTSYMCKCAEGYGGDLCDNKND 1407
Query: 1135 SKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCL 1183
S C G C C G +G+ CQ + NPCL
Sbjct: 1408 SANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ------QENPCL 1450
Score = 76.3 bits (186), Expect = 2e-13
Identities = 45/165 (27%), Positives = 64/165 (38%), Gaps = 24/165 (14%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPC--------HSAPCARGRCHTH 1111
C + C ++ C D + + C C P + G C+ +D C H A C
Sbjct: 1000 CEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIP------ 1053
Query: 1112 PDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQ 1171
D F C C PG+ G C + +C + C G+ C C+C +G +G C+
Sbjct: 1054 LDKGFSCECVPGYSGKLCE--TDNDDCVAH-KCRHGAQCVDTINGYTCTCPQGFSGPFCE 1110
Query: 1172 VP-------TLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
P T PC+ C NG C C C F+G CE
Sbjct: 1111 HPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
Score = 73.9 bits (180), Expect = 9e-13
Identities = 42/122 (34%), Positives = 54/122 (44%), Gaps = 14/122 (11%)
Query: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDI-DECASRPCHHGATCRNLADRYECHC 134
C HG LC + + C C PG+ GP C+ + D C CHHG C Y C C
Sbjct: 1338 CKHG-LC--RSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKC 1393
Query: 135 PLGYAGVTCEMEVDE---CASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQ 191
GY G C+ + D C++ C HG + G C+C PG+ G CQ Q
Sbjct: 1394 AEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ------QEN 1447
Query: 192 PC 193
PC
Sbjct: 1448 PC 1449
Score = 64.7 bits (156), Expect = 5e-10
Identities = 40/112 (35%), Positives = 50/112 (44%), Gaps = 8/112 (7%)
Query: 117 CHHGATCRNLA-DRYECHCPLGYAGVTCEMEV-DECASAPCLHGGSCLDGVGSFRCVCAP 174
C HG CR++ D C C G+ G C+ E D C C H G C+ S+ C CA
Sbjct: 1338 CKHGL-CRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRC-HHGKCVATGTSYMCKCAE 1395
Query: 175 GYGGTRCQLDLDE---CQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCERE 223
GYGG C D C + C H G CH G G+ G HC++E
Sbjct: 1396 GYGGDLCDNKNDSANACSAFKC-HHGQCHISDQGEPYCLCQPGFSGEHCQQE 1446
Score = 60.5 bits (145), Expect = 1e-08
Identities = 38/115 (33%), Positives = 49/115 (42%), Gaps = 7/115 (6%)
Query: 155 CLHGGSCLDGVGSFRCVCAPGYGGTRCQLDL-DECQSQPCAHGGTCHDLVNGFRCDCAGT 213
C HG S C C PG+ G C + D C C HG C + C CA
Sbjct: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCA-E 1395
Query: 214 GYEGTHCERE---VLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDEC 265
GY G C+ + C++ C H + G CLC PG+SGE C+ E+ C
Sbjct: 1396 GYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ-QENPC 1449
Score = 55.1 bits (131), Expect = 4e-07
Identities = 36/119 (30%), Positives = 47/119 (39%), Gaps = 10/119 (8%)
Query: 324 CASRPCLNGGHCQDLP-NGFQCHCPDGYAGPTCEEDV-DECLSDPCLHGGTCSDTVAGYI 381
C S G C+ + + C C G+ GP C+++ D CL C H G C T Y+
Sbjct: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRC-HHGKCVATGTSYM 1390
Query: 382 CRCPETWGGRDC---SVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437
C+C E +GG C + C C I S C C PG G C Q
Sbjct: 1391 CKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHI----SDQGEPYCLCQPGFSGEHCQQ 1445
Score = 53.5 bits (127), Expect = 1e-06
Identities = 35/105 (33%), Positives = 45/105 (42%), Gaps = 10/105 (9%)
Query: 1110 THPDGRFECRCPPGFG-GPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQ 1168
T P RF+C+ P +C + S C N TC P E C+C G+
Sbjct: 897 TTPTHRFQCKGPVDINIVAKCNACL-SSPCKNNGTCTQ-DPVE----LYRCACPYSYKGK 950
Query: 1169 RCQVPTLPCEANPCLNGGTCRAAGGVSE---CICNARFSGQFCEV 1210
C VP C NPC +GGTC + + C C F GQ CE+
Sbjct: 951 DCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEI 995
Score = 50.4 bits (119), Expect = 1e-05
Identities = 40/148 (27%), Positives = 56/148 (37%), Gaps = 34/148 (22%)
Query: 188 CQSQPCAHGGTCHDLV-NGFRCDCAGTGYEGTHCEREVLE-CASAPCEHNASCLEGLGSF 245
C+S G C + + C+C G+ G C++E + C C H+ C+ S+
Sbjct: 1332 CKSCTVCKHGLCRSVEKDSVVCECR-PGWTGPLCDQEARDPCLGHRC-HHGKCVATGTSY 1389
Query: 246 RCLCWPGYSGELCEVDEDE---CASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAA 302
C C GY G+LC+ D C++ C H G+C Y
Sbjct: 1390 MCKCAEGYGGDLCDNKNDSANACSAFKCHH-GQCHISDQGEPY----------------- 1431
Query: 303 GFLCHCPPGFEGADCGVEVDECASRPCL 330
C C PGF G C E PCL
Sbjct: 1432 ---CLCQPGFSGEHCQQE------NPCL 1450
Score = 49.3 bits (116), Expect = 2e-05
Identities = 29/102 (28%), Positives = 39/102 (38%), Gaps = 6/102 (5%)
Query: 305 LCHCPPGFEGADCGVEV-DECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE---EDVD 360
+C C PG+ G C E D C C + G C + C C +GY G C+ + +
Sbjct: 1352 VCECRPGWTGPLCDQEARDPCLGHRC-HHGKCVATGTSYMCKCAEGYGGDLCDNKNDSAN 1410
Query: 361 ECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQG 402
C + C HG C C + G C Q C G
Sbjct: 1411 ACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ-QENPCLG 1451
Score = 48.5 bits (114), Expect = 4e-05
Identities = 64/276 (23%), Positives = 98/276 (35%), Gaps = 55/276 (19%)
Query: 609 CRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIPAATFGLGGAPSSASFLLQELPGP 668
C C +G C+ + C C GP C I G AS ++ P
Sbjct: 1123 CDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKDSYVELASAKVR----P 1178
Query: 669 NLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPG--RWDDGLR 726
+S + T + G+LL ++ L ++ R+ + SP + +DG
Sbjct: 1179 QANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQF 1238
Query: 727 HLVML-----------------SFGPDQLQD---LGQHVHVGG--------RLLAADSQP 758
H V L S G Q Q + +++GG L +P
Sbjct: 1239 HSVELVTLNQTLNLVVDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRP 1298
Query: 759 WGGPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELGGRQSWNLTAGCVSEDMCSPDPCFN 818
GG F GC+ ++R++ F LP P LG ++ GC S +C C +
Sbjct: 1299 LGG-FHGCIHEVRINNELQDFKALP------PQSLG------VSPGCKSCTVCKHGLCRS 1345
Query: 819 GGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCL 854
V + C C +TGP C Q+ PCL
Sbjct: 1346 -----VEKDSVVCECRPGWTGPLCDQE---ARDPCL 1373
Score = 47.0 bits (110), Expect = 1e-04
Identities = 35/142 (24%), Positives = 56/142 (39%), Gaps = 34/142 (23%)
Query: 232 CEHNASCLEGLGSFRCLCWPGYSGELCEVD-EDECASSPCQHGGRCLQRSDPALYGGVQA 290
C+H S C C PG++G LC+ + D C C H G+C+
Sbjct: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHH-GKCVAT----------- 1385
Query: 291 AFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDE---CASRPCLNGG-HCQDLPNGFQCHC 346
++C C G+ G C + D C++ C +G H D + C C
Sbjct: 1386 ----------GTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPY-CLC 1434
Query: 347 PDGYAGPTCEEDVDECLSDPCL 368
G++G C+++ +PCL
Sbjct: 1435 QPGFSGEHCQQE------NPCL 1450
Score = 42.0 bits (97), Expect = 0.004
Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 3/66 (4%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQ--PCLPPATCEEV 862
++ D C + C N TC+ N++ C CP N+TG C + + C + C A C +
Sbjct: 995 INPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPL 1054
Query: 863 PDGFVC 868
GF C
Sbjct: 1055 DKGFSC 1060
Score = 41.6 bits (96), Expect = 0.005
Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 4/68 (5%)
Query: 811 CSPDPCFNGGTCLVT---WNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGF 866
C +PC +GGTC ++ + F C+CP F G C C C ATC + + +
Sbjct: 959 CIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNY 1018
Query: 867 VCVAEATF 874
VC+ +
Sbjct: 1019 VCICPPNY 1026
Score = 40.4 bits (93), Expect = 0.011
Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 8/74 (10%)
Query: 800 NLTAGCVSEDMCSPDPCFNGGTCLVTWND-FHCTCPANFTGPTCAQQL-WCPGQPCLPPA 857
N+ A C + C PC N GTC + + C CP ++ G C + C PC
Sbjct: 912 NIVAKC---NACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGG 968
Query: 858 TC---EEVPDGFVC 868
TC + DGF C
Sbjct: 969 TCHLSDSHKDGFSC 982
Score = 35.8 bits (81), Expect = 0.27
Identities = 40/144 (27%), Positives = 50/144 (34%), Gaps = 40/144 (27%)
Query: 43 ASDPC-----------APGTE--CQATES-GGYTCGPMEP--RGCATQPCHHGALCVPQG 86
A DPC A GT C+ E GG C C+ CHHG +
Sbjct: 1368 ARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQ 1427
Query: 87 PDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME 146
+P C C PGF G C+ + PC G R + R + GYA
Sbjct: 1428 GEPY---CLCQPGFSGEHCQQE------NPC-LGQVVREVIRRQK-----GYA------- 1465
Query: 147 VDECASAPCLHGGSCLDGVGSFRC 170
CA+A + C G G C
Sbjct: 1466 --SCATASKVPIMECRGGCGPQCC 1487
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 181 bits (458), Expect = 5e-45
Identities = 121/371 (32%), Positives = 163/371 (43%), Gaps = 63/371 (16%)
Query: 66 MEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDEC-----ASRPCHHG 120
++ + C++ PC +G C+ F C C P ++GP C D++EC C +G
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDS---FFCICPPQWKGPLCSADVNECEIYSGTPLSCQNG 187
Query: 121 ATCRNLADRYECHCPLGYAGVTCEMEVDECAS---APCLHGGSCLD------GVGSFRCV 171
TC N Y CHCP G C + D+C A C+HG C D G + CV
Sbjct: 188 GTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYSCV 246
Query: 172 CAPGY----GGTRCQLDLDECQSQP--CAHGGTCHDLVNGFRCDCAGTGYEGT------- 218
C G+ C LD DEC QP C+ C + F C TG++G
Sbjct: 247 CDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDI 306
Query: 219 -HCEREVLECASAPCEHNASCLEGLGSFRC-LCWPGYSGE--LCEVDEDECASSPCQHGG 274
CE C+ AP C+ GS C C PGY G+ +C + D C+ S +GG
Sbjct: 307 NECEINNGGCSVAP---PVECVNTPGSSHCQACPPGYQGDGRVCTLT-DICSVS---NGG 359
Query: 275 RCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCG----VEVDE-CASRPC 329
S + G + LC C PG+ G G V++ C S PC
Sbjct: 360 CHPDASCSSTLGSLP---------------LCTCLPGYTGNGYGPNGCVQLSNICLSHPC 404
Query: 330 LNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWG 389
LNG C D +G+ C C G+ G C E+++ECLS+PCL+GGTC D V + C C W
Sbjct: 405 LNG-QCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWT 463
Query: 390 GRDCSVQLTGC 400
G C V C
Sbjct: 464 GALCQVPQQVC 474
Score = 97.8 bits (242), Expect = 6e-20
Identities = 89/315 (28%), Positives = 119/315 (37%), Gaps = 80/315 (25%)
Query: 47 CAPGTECQATESGGYTCG-PMEPRG--CATQ----------PCHHGA---LCVPQGPDPT 90
C G C T G Y+C P E G CA++ C HG L Q +P
Sbjct: 184 CQNGGTCVNT-MGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPK 242
Query: 91 GFRCYCVPGFQ----GPRCELDIDECASRP--CHHGATCRNLADRYECH-CPLGYAGV-- 141
+ C C G+ P C LD DEC+ +P C C N + C CP G+ G
Sbjct: 243 -YSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGY 301
Query: 142 ------TCEMEVDECASAP---------------------------------------CL 156
CE+ C+ AP C
Sbjct: 302 ICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCH 361
Query: 157 HGGSCLDGVGSFR-CVCAPGYGGTR-----CQLDLDECQSQPCAHGGTCHDLVNGFRCDC 210
SC +GS C C PGY G C + C S PC +G C D V+G+ C C
Sbjct: 362 PDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFCKC 420
Query: 211 AGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPC 270
+G+ G +C + EC S PC + +C++G+ SF C C ++G LC+V + C S
Sbjct: 421 -DSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLS 479
Query: 271 QHGGRCLQRSDPALY 285
G RS Y
Sbjct: 480 GINGSFSYRSPDVGY 494
Score = 82.8 bits (203), Expect = 2e-15
Identities = 44/130 (33%), Positives = 61/130 (46%), Gaps = 15/130 (11%)
Query: 312 FEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDEC-----LSDP 366
F+G V+ C+S PC NGG C +L + F C CP + GP C DV+EC
Sbjct: 124 FQGLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLS 183
Query: 367 CLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIF-------ESGV 419
C +GGTC +T+ Y C CP G C+ + C+G + A C+ ++G
Sbjct: 184 CQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGS---VARCVHGICEDLMREQAGE 240
Query: 420 HSYVCHCPPG 429
Y C C G
Sbjct: 241 PKYSCVCDAG 250
Score = 73.6 bits (179), Expect = 1e-12
Identities = 39/117 (33%), Positives = 51/117 (43%), Gaps = 12/117 (10%)
Query: 1059 VCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCH-----SAPCARGRCHTHPD 1113
VC+ +PC + G C +L D+F C C P W+GP C A V+ C C G +
Sbjct: 135 VCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTM 194
Query: 1114 GRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCE------GGSPAANCSCLEG 1164
G + C CPP GP+C E C+ G CE G P +C C G
Sbjct: 195 GSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPKYSCVCDAG 250
Score = 62.8 bits (151), Expect = 2e-09
Identities = 49/160 (30%), Positives = 65/160 (40%), Gaps = 13/160 (8%)
Query: 1035 PGAREHFASWPGTPAPILGCRGAPVCAPSP--CLHDGACRDLFDAFA-CACGPGWEGPR- 1090
PG+ A PG C +C+ S C D +C + C C PG+ G
Sbjct: 328 PGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGY 387
Query: 1091 ----CEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLD 1146
C + C S PC G+C G F C+C G+ G C + EC N CL+
Sbjct: 388 GPNGCVQLSNICLSHPCLNGQCIDTVSGYF-CKCDSGWTGVNCTENI--NECLSN-PCLN 443
Query: 1147 GSPCEGGSPAANCSCLEGLAGQRCQVPTLPC-EANPCLNG 1185
G C G + +C C G CQVP C E+ +NG
Sbjct: 444 GGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGING 483
Score = 59.7 bits (143), Expect = 2e-08
Identities = 62/224 (27%), Positives = 73/224 (32%), Gaps = 58/224 (25%)
Query: 1042 ASW---PGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFAC-ACGPGWEGP-------- 1089
A W P +PA L R P PC C + +F C AC GW+G
Sbjct: 249 AGWMFSPNSPACTLD-RDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDIN 307
Query: 1090 RCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPR--CRLPV----------PSKE 1137
CE + C AP C P CPPG+ G C L P
Sbjct: 308 ECEINNGGCSVAPPVE--CVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDAS 365
Query: 1138 CSLNV------TCLDG--------------------SPCEGGSPAAN-----CSCLEGLA 1166
CS + TCL G PC G C C G
Sbjct: 366 CSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWT 425
Query: 1167 GQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
G C C +NPCLNGGTC C C ++G C+V
Sbjct: 426 GVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQV 469
Score = 58.5 bits (140), Expect = 4e-08
Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 3/90 (3%)
Query: 1059 VCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFEC 1118
+C PCL+ G C D + C C GW G C +++ C S PC G F C
Sbjct: 398 ICLSHPCLN-GQCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSC 456
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGS 1148
C + G C+ VP + C +++ ++GS
Sbjct: 457 ECTRLWTGALCQ--VPQQVCGESLSGINGS 484
Score = 49.3 bits (116), Expect = 2e-05
Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
Query: 804 GCVS-EDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEE 861
GCV ++C PC NG C+ T + + C C + +TG C + + C PCL TC +
Sbjct: 391 GCVQLSNICLSHPCLNG-QCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVD 449
Query: 862 VPDGFVC 868
D F C
Sbjct: 450 GVDSFSC 456
Score = 47.8 bits (112), Expect = 7e-05
Identities = 18/38 (47%), Positives = 24/38 (63%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCA 843
V + +CS +PC NGGTCL + F C CP + GP C+
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCS 168
Score = 45.4 bits (106), Expect = 3e-04
Identities = 31/121 (25%), Positives = 45/121 (37%), Gaps = 24/121 (19%)
Query: 1098 CHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLN----VTCLDGSPCEGG 1153
C S PC G + F C CPP + GP C V EC + ++C +G C
Sbjct: 136 CSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADV--NECEIYSGTPLSCQNGGTCVNT 193
Query: 1154 SPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSE-------------CICN 1200
+ +C C G +C + + C G R G+ E C+C+
Sbjct: 194 MGSYSCHCPPETYGPQC-----ASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCD 248
Query: 1201 A 1201
A
Sbjct: 249 A 249
Score = 38.9 bits (89), Expect = 0.032
Identities = 15/34 (44%), Positives = 19/34 (55%)
Query: 812 SPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQ 845
+P C NGGTC+ T + C CP GP CA +
Sbjct: 180 TPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASK 213
Score = 38.9 bits (89), Expect = 0.032
Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 604 ERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIPAATFG--LGGAPSSASF 660
E +C PC++GG+CVD F C+C R G C ++P G L G S S+
Sbjct: 431 ENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALC--QVPQQVCGESLSGINGSFSY 487
Score = 37.7 bits (86), Expect = 0.071
Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 7/47 (14%)
Query: 1177 CEANPCLNGGTCRAAGGVSECICNARFSGQF-------CEVAKGLPL 1216
C +NPC NGGTC CIC ++ G CE+ G PL
Sbjct: 136 CSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPL 182
Score = 37.4 bits (85), Expect = 0.093
Identities = 14/32 (43%), Positives = 18/32 (56%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC 842
C +PC NGGTC+ + F C C +TG C
Sbjct: 436 CLSNPCLNGGTCVDGVDSFSCECTRLWTGALC 467
Score = 36.6 bits (83), Expect = 0.16
Identities = 13/39 (33%), Positives = 23/39 (58%)
Query: 606 REQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
++ C PC +GG+C++L F C C +GP C+ ++
Sbjct: 133 KKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADV 171
Score = 35.0 bits (79), Expect = 0.46
Identities = 25/81 (30%), Positives = 27/81 (33%), Gaps = 6/81 (7%)
Query: 1133 VPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANP-----CLNGGT 1187
V K CS N C +G C + C C G C CE C NGGT
Sbjct: 131 VDKKVCSSN-PCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGT 189
Query: 1188 CRAAGGVSECICNARFSGQFC 1208
C G C C G C
Sbjct: 190 CVNTMGSYSCHCPPETYGPQC 210
Score = 34.3 bits (77), Expect = 0.79
Identities = 13/33 (39%), Positives = 18/33 (54%)
Query: 611 PLPCVHGGSCVDLWTHFRCDCARPHRGPTCADE 643
PL C +GG+CV+ + C C GP CA +
Sbjct: 181 PLSCQNGGTCVNTMGSYSCHCPPETYGPQCASK 213
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 175 bits (443), Expect = 3e-43
Identities = 154/460 (33%), Positives = 199/460 (43%), Gaps = 92/460 (20%)
Query: 25 PALSLLAGTVPSEPPSA-----CASDP--CAPGTECQATESGGYTCG--------PMEPR 69
P S+ A T P P S C +P C PG C + SG YTC P R
Sbjct: 460 PLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPG-RCISRPSG-YTCACDSGFRLSPQGTR 517
Query: 70 GCATQPCHH-GALCVPQGPD--PTGFRCYCVPGFQ-GPRCE--LDIDEC--ASRPCHHGA 121
C C P + P FRC C PGF+ GPR LD+DEC PC G
Sbjct: 518 CIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGR 577
Query: 122 TCRNLADRYECHCPLGYA----GVTCEMEVDECASAPCLHG-GSCLDGVGSFRCVCAPGY 176
C N + C CP GY G +C+ +VDEC +P L G G+C + GSFRCVC G+
Sbjct: 578 -CENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGF 635
Query: 177 GGTRCQLDLDECQSQPCAHG-GTCHDLVNGFRCDCAGTGYE----GTHCEREVLECASA- 230
G+ C+ D+DEC +P G G C + F C C G+ G C+ +V ECA +
Sbjct: 636 RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACP-AGFRSRGPGAPCQ-DVDECARSP 693
Query: 231 -PCEHNASCLEGLGSFRCLC----WPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALY 285
PC + C GSF+C+C P +G CE D DEC + G C+
Sbjct: 694 PPCTY-GRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNS------ 745
Query: 286 GGVQAAFPGAFSFRHAAGFLCHCPPG--FEGADCGVEVDECAS--RPCLNGGHCQDLPNG 341
PG+F R CP G C +VDEC+S PC GHC +
Sbjct: 746 -------PGSFQCR-------TCPSGHHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGS 790
Query: 342 FQCHCPDGYAGPTCE----EDVDECL-SDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQ 396
F+C C GY P+ DV+ECL D C G C +T + C C +
Sbjct: 791 FRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGY-------- 842
Query: 397 LTGCQGHTCPLAATCI--PIFESGV-----HSYVCHCPPG 429
G +G +C C + +SG+ S+ C CPPG
Sbjct: 843 RPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPG 882
Score = 162 bits (411), Expect = 1e-39
Identities = 139/447 (31%), Positives = 175/447 (39%), Gaps = 75/447 (16%)
Query: 46 PCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALC--VPQGPD-------PTGFRCYC 96
PCAPG + S CGP G C C VP D P F C C
Sbjct: 530 PCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVC 589
Query: 97 VPGFQ----GPRCELDIDECASRP--CHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC 150
G+Q G C+ D+DEC P C GA C+NL + C CP G+ G CE +VDEC
Sbjct: 590 PAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDEC 647
Query: 151 ASAPCLHG-GSCLDGVGSFRCVCAPGYG----GTRCQLDLDECQSQP--CAHGGTCHDLV 203
A P G G C + GSF C C G+ G CQ D+DEC P C +G C +
Sbjct: 648 AQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYG-RCENTE 705
Query: 204 NGFRCDCAGTGYE----GTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPG----YSG 255
F+C C G++ G+ CE +V EC + C+ GSF+C P + G
Sbjct: 706 GSFQCVCP-MGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG 763
Query: 256 ELCEVDEDECASSPCQHGGRCLQRSD----------------PALYGGVQAAFPGAFSFR 299
+VDE + PC G C P V G F F
Sbjct: 764 RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFP 823
Query: 300 HA------AGFLCHCPPGFE----GADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDG 349
H F C C PG+ GA C ++VDEC+ G C + F+C CP G
Sbjct: 824 HGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPG 882
Query: 350 Y-AGPTCEE--DVDECLS-DPCLHGG-TCSDTVAGYICRCPETWGGRDCSVQLTGCQGHT 404
+ AGP DVDEC P L G C ++ Y C RDC T
Sbjct: 883 HRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRC-------VRDCDPGYHAGPEGT 935
Query: 405 CPLAATCIPIFESGVHSYVCHCPPGTH 431
C C + C PG++
Sbjct: 936 CDDVDECQEYGPEICGAQRCENTPGSY 962
Score = 140 bits (352), Expect = 1e-32
Identities = 131/429 (30%), Positives = 176/429 (41%), Gaps = 84/429 (19%)
Query: 32 GTVPSEPPSACASDP--CAPGTECQATESGGYTC---------GPMEP----RGCATQP- 75
G+ E CA +P C PG C T +G + C GP P CA P
Sbjct: 637 GSACEEDVDECAQEPPPCGPG-RCDNT-AGSFHCACPAGFRSRGPGAPCQDVDECARSPP 694
Query: 76 -CHHGALCVPQGPDPTGFRCYCVPGFQ----GPRCELDIDECASRPCHHGATCRNLADRY 130
C +G +G F+C C GFQ G CE D+DEC + G C N +
Sbjct: 695 PCTYGRCENTEG----SFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSF 749
Query: 131 ECH-CPLGYA--GVTCEMEVDECASA--PCLHGGSCLDGVGSFRCVCAPGY----GGTRC 181
+C CP G+ C +VDEC+S PC G C + GSFRC CAPGY G
Sbjct: 750 QCRTCPSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP 808
Query: 182 QLDLDEC-QSQPCAHGGTCHDLVNGFRCDCAG---TGYEGTHCEREVLECASAPCEHNAS 237
D++EC + C G C + F C CA G G C +V EC+ +
Sbjct: 809 CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGI 867
Query: 238 CLEGLGSFRCLCWPGYSG-----ELCEVDEDE------CASSPCQHGG---RCLQRSDPA 283
C GSF C+C PG+ +VDE C S C++ RC++ DP
Sbjct: 868 CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPG 927
Query: 284 LYGGVQAAFPGAFSFRHAAGFLCH----------------CPPGFE---GADCGVEVDEC 324
+ G + + +C C PG++ G C +VDEC
Sbjct: 928 YHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDEC 986
Query: 325 ASRPCLNGGH--CQDLPNGFQCHCPDGYAGPTCEE---DVDECLSDPCLHGGTCSDTVAG 379
+R G H CQ+LP FQC C GY G DV+EC + + G + V G
Sbjct: 987 RNRSFC-GAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEG 1045
Query: 380 -YICRCPET 387
++C CP +
Sbjct: 1046 SFLCVCPNS 1054
Score = 115 bits (288), Expect = 3e-25
Identities = 92/279 (32%), Positives = 118/279 (42%), Gaps = 66/279 (23%)
Query: 188 CQSQPCAHG-GTCHDLVNGFRCDCAGTGY----EGTHCEREVLECASAP--CEHNASCLE 240
CQ P G G C +G+ C C +G+ +GT C +V EC P C C
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCAC-DSGFRLSPQGTRCI-DVDECRRVPPPCAPGR-CEN 538
Query: 241 GLGSFRCLCWPGY-----SGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGA 295
GSFRC+C PG+ + E +VDE PC G RC PG+
Sbjct: 539 SPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLG-RCENT-------------PGS 584
Query: 296 FSFRHAAGFLCHCPPGFEGADCGV---EVDECASRPCLNG-GHCQDLPNGFQCHCPDGYA 351
F LC CP G++ A G +VDEC P L G G C++LP F+C CP G+
Sbjct: 585 F--------LCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR 636
Query: 352 GPTCEEDVDECLSDPCLHG-GTCSDTVAGYICRCPETWGGR----------DCSVQLTGC 400
G CEEDVDEC +P G G C +T + C CP + R +C+ C
Sbjct: 637 GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC 696
Query: 401 QGHTCPLAATCIPIFESGVHSYVCHCP----PGTHGPFC 435
C E+ S+ C CP P T G C
Sbjct: 697 TYGRC----------ENTEGSFQCVCPMGFQPNTAGSEC 725
Score = 103 bits (258), Expect = 8e-22
Identities = 130/506 (25%), Positives = 169/506 (33%), Gaps = 147/506 (29%)
Query: 46 PCAPGTECQATESG-------GYTCGPMEPRGCA-TQPCHHGALCVPQGP---DPTGFRC 94
PC P C TE GY P CA C G C P G F C
Sbjct: 777 PCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFAC 836
Query: 95 YCVPGFQ-GPRCE--LDIDECASRPCHHGATCRNLADRYECHCPLGYAG----VTCEMEV 147
C PG++ GPR LD+DEC+ C N +EC CP G+ +C ++V
Sbjct: 837 TCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-LDV 895
Query: 148 DECAS-APCLHGGS-CLDGVGSFRCV--CAPGY----------------------GGTRC 181
DEC P L G C + GS+RCV C PGY G RC
Sbjct: 896 DECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRC 955
Query: 182 Q------------------------LDLDECQSQP-CAHGGTCHDLVNGFRCDCAGTGYE 216
+ D+DEC+++ C C +L F+C C GYE
Sbjct: 956 ENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLC-DQGYE 1014
Query: 217 GT----HCEREVLECASAPCEHNASCLEGL-GSFRCLCW---------------PGYSGE 256
G HC +V EC + A+ E + GSF C+C P S
Sbjct: 1015 GARDGRHCV-DVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAG 1073
Query: 257 LCEVDEDECASSPCQHGGR---------CLQRSDPALYGGVQAAFPGA-------FSFRH 300
+ + +SP R P G + F A R+
Sbjct: 1074 TFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARN 1133
Query: 301 AAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDG--YAGPTCE-- 356
C C G EG G + +C +Q CP G Y P+ +
Sbjct: 1134 VTWQECCCTVG-EGWGSGCRIQQCPGTETAE----------YQSLCPHGRGYLAPSGDLS 1182
Query: 357 --EDVDEC--LSDPCLHGGTCSDTVAGYICRCP----------ETWGGRDCSVQLTGCQG 402
DVDEC D G C +T GY C C E +C+ + C+G
Sbjct: 1183 LRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG 1242
Query: 403 HTCPLAATCIPIFESGVHSYVCHCPP 428
C + V SY C C P
Sbjct: 1243 GRC----------VNTVGSYHCTCEP 1258
Score = 81.6 bits (200), Expect = 4e-15
Identities = 73/219 (33%), Positives = 85/219 (38%), Gaps = 34/219 (15%)
Query: 1016 RVALGGLPL----PLARPRPGAAPGAREHFAS---WPGTPAPILG-----CRGAP-VCAP 1062
R + G LP P PRP PG S W G P G C+ P VC P
Sbjct: 432 RPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGP 491
Query: 1063 SPCLHDGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAP--CARGRCHTHPDGRF 1116
C+ + + CAC G+ +G RC VD C P CA GRC P G F
Sbjct: 492 GRCISRPS------GYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGRCENSP-GSF 543
Query: 1117 ECRCPPGF-GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLA----GQRCQ 1171
C C PGF GPR + EC D CE + C C G G CQ
Sbjct: 544 RCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ 603
Query: 1172 VPTLPCEANPCLNG-GTCRAAGGVSECICNARFSGQFCE 1209
C +P L G G C+ G C+C A F G CE
Sbjct: 604 -DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACE 641
Score = 81.3 bits (199), Expect = 6e-15
Identities = 117/453 (25%), Positives = 158/453 (34%), Gaps = 96/453 (21%)
Query: 42 CASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQ 101
CAS T+ G G + + C+ + + + P GP PTGF
Sbjct: 231 CASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERV------ 284
Query: 102 GPRCELDIDECASRP-CHHGATCRNLADRYECHCPLGY----AGVTC-EMEVDECASAPC 155
CE D+DECA+ C HG C N Y C CP G+ + +C V A PC
Sbjct: 285 NGSCE-DVDECATGGRCQHGE-CANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC 342
Query: 156 ---LHGGSC----LDGVGSFRCVC-----APGYGGTRCQLDLDECQSQPCAHGGTCHDLV 203
L G C L + C C A G G C E + C G H
Sbjct: 343 FRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSA 402
Query: 204 NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLG---------------SFRCL 248
+ R + G E A +A L
Sbjct: 403 SDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLP 462
Query: 249 CWPGYSGELCEVDEDECASSPCQHG------GRCLQRSDPALYGGVQAAFPGAFSFRHAA 302
P ++G E+ E +S CQ GRC+ R +
Sbjct: 463 SIPAWTGP--EIPESGPSSGMCQRNPQVCGPGRCISRP---------------------S 499
Query: 303 GFLCHCPPGF----EGADCGVEVDEC--ASRPCLNGGHCQDLPNGFQCHCPDGY-AGPTC 355
G+ C C GF +G C ++VDEC PC G C++ P F+C C G+ AGP
Sbjct: 500 GYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRA 557
Query: 356 EE--DVDEC--LSDPCLHGGTCSDTVAGYICRCPETWG----GRDCSV--QLTGCQGHTC 405
E DVDEC + PC G C +T ++C CP + G C + T G
Sbjct: 558 AECLDVDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCG 616
Query: 406 PLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438
A +P S+ C CP G G C ++
Sbjct: 617 RGACKNLP------GSFRCVCPAGFRGSACEED 643
Score = 67.8 bits (164), Expect = 6e-11
Identities = 48/152 (31%), Positives = 61/152 (40%), Gaps = 10/152 (6%)
Query: 1054 CRGAPVCAPSPCLHD-GACRDLFDAFACACGPGWEGPRCEAHVDPC--HSAPCARGRCHT 1110
C+ C SP L GAC++L +F C C G+ G CE VD C PC GRC
Sbjct: 602 CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRC-D 660
Query: 1111 HPDGRFECRCPPGFGGPRCRLPVPS-KECSLNVTCLDGSPCEGGSPAANCSCLEGL---- 1165
+ G F C CP GF P EC+ + CE + C C G
Sbjct: 661 NTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNT 720
Query: 1166 AGQRCQVPTLPCEANPCLNGGTCRAAGGVSEC 1197
AG C+ CE + G C + G +C
Sbjct: 721 AGSECE-DVDECENHLACPGQECVNSPGSFQC 751
Score = 58.2 bits (139), Expect = 5e-08
Identities = 48/136 (35%), Positives = 57/136 (41%), Gaps = 13/136 (9%)
Query: 1030 RPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWE-G 1088
R APG R + PG A + C C P G C + +FAC C PG+ G
Sbjct: 792 RCSCAPGYRAP-SGRPGPCADVNECLEGDFCFPH-----GECLNTDGSFACTCAPGYRPG 845
Query: 1089 PRCEA--HVDPCHSAP-CARGRCHTHPDGRFECRCPPGF-GGPRCRLPVPSKECSLNVTC 1144
PR + VD C C G C T+ DG FEC CPPG GP + EC
Sbjct: 846 PRGASCLDVDECSEEDLCQSGIC-TNTDGSFECICPPGHRAGPDLASCLDVDECRERGPA 904
Query: 1145 LDGSP-CEGGSPAANC 1159
L GS CE + C
Sbjct: 905 LCGSQRCENSPGSYRC 920
Score = 57.8 bits (138), Expect = 7e-08
Identities = 54/178 (30%), Positives = 70/178 (39%), Gaps = 28/178 (15%)
Query: 24 APALSLLAGTVPSEP----PSACASDPCAPGT-ECQATESGGYTCGPMEPRGCATQPC-- 76
APA +L P P PS P G EC + C + R Q C
Sbjct: 1082 APASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCC 1141
Query: 77 ----HHGALCVPQ---GPDPTGFRCYCVPG--FQGPRCEL----DIDECA---SRPCHHG 120
G+ C Q G + ++ C G + P +L D+DEC + C G
Sbjct: 1142 TVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSG 1201
Query: 121 ATCRNLADRYECHCPLGYAGVTCEMEV---DECASA-PCLHGGSCLDGVGSFRCVCAP 174
C N A Y C+C GY T +E DECA P GG C++ VGS+ C C P
Sbjct: 1202 V-CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1258
Score = 53.9 bits (128), Expect = 1e-06
Identities = 50/169 (29%), Positives = 63/169 (37%), Gaps = 23/169 (13%)
Query: 1045 PGTPAPILGCRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE----GPRCEAHVDPC 1098
PG P C+ CA P PC + G C + +F C C G++ G CE VD C
Sbjct: 679 PGAP-----CQDVDECARSPPPCTY-GRCENTEGSFQCVCPMGFQPNTAGSECE-DVDEC 731
Query: 1099 HSAPCARGRCHTHPDGRFECR-CPPGFGGPRCRLPVPSKECSLNV-TCLDGSPCEGGSPA 1156
+ G+ + G F+CR CP G R R ECS C C +
Sbjct: 732 ENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGS 790
Query: 1157 ANCSCLEGLAGQRCQVPTLPCEANPCLNG------GTCRAAGGVSECIC 1199
CSC G + P + N CL G G C G C C
Sbjct: 791 FRCSCAPGYRAPSGR-PGPCADVNECLEGDFCFPHGECLNTDGSFACTC 838
Score = 52.4 bits (124), Expect = 3e-06
Identities = 50/167 (29%), Positives = 62/167 (37%), Gaps = 33/167 (19%)
Query: 1056 GAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSA-PCARGR-CHTH-- 1111
GAP C P G C + +F C+C PG+ P PC C G C H
Sbjct: 774 GAPPCGPH-----GHCTNTEGSFRCSCAPGYRAP--SGRPGPCADVNECLEGDFCFPHGE 826
Query: 1112 ---PDGRFECRCPPGF-GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEG-LA 1166
DG F C C PG+ GPR + ECS C G C + C C G A
Sbjct: 827 CLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGI-CTNTDGSFECICPPGHRA 885
Query: 1167 GQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKG 1213
G + CL+ CR G +C + Q CE + G
Sbjct: 886 GP---------DLASCLDVDECRERG---PALCGS----QRCENSPG 916
Score = 45.8 bits (107), Expect = 3e-04
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 9/85 (10%)
Query: 103 PRCELDIDECASRPCHHGATCRNLADRYECHCPLGY----AGVTCEMEVDEC----ASAP 154
P EL+ +EC C + + + C C GY + C ++++EC A++P
Sbjct: 1461 PYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASP 1519
Query: 155 CLHGGSCLDGVGSFRCVCAPGYGGT 179
CL+ GSFRC+C PG+ T
Sbjct: 1520 LCVNARCLNTDGSFRCICRPGFAPT 1544
Score = 45.4 bits (106), Expect = 3e-04
Identities = 26/82 (31%), Positives = 30/82 (36%), Gaps = 3/82 (3%)
Query: 803 AGCVSEDMCSPDPCFNG-GTCLVTWNDFHCTCPANFTGPTCAQQL--WCPGQPCLPPATC 859
A C D C+ P G G C F C CPA F G C + + P P C
Sbjct: 600 ASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRC 659
Query: 860 EEVPDGFVCVAEATFREGPPAA 881
+ F C A FR P A
Sbjct: 660 DNTAGSFHCACPAGFRSRGPGA 681
Score = 43.5 bits (101), Expect = 0.001
Identities = 60/247 (24%), Positives = 79/247 (31%), Gaps = 33/247 (13%)
Query: 155 CLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVN----GFRCDC 210
C +GG C V RC+C P + G CQL + A G + R D
Sbjct: 90 CHNGGVC---VKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDD- 145
Query: 211 AGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPC 270
E V S EH + + P + V E A+
Sbjct: 146 ----------EHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAE 195
Query: 271 QHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCP-PGFE-------GADCGVEVD 322
+ G A + FR G C P PG GA V
Sbjct: 196 AAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVH 255
Query: 323 ECA-SRPCLNGGHCQDLPNGFQCHCPDGY--AGPTCEEDVDECLSDPCLHGGTCSDTVAG 379
+C L P+G CP G+ +CE DVDEC + G C++T G
Sbjct: 256 DCQLCSERLGNSERVSAPDG---PCPTGFERVNGSCE-DVDECATGGRCQHGECANTRGG 311
Query: 380 YICRCPE 386
Y C CP+
Sbjct: 312 YTCVCPD 318
Score = 43.5 bits (101), Expect = 0.001
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 14/83 (16%)
Query: 182 QLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLEC----------ASAP 231
+L+ +EC G C + GF C C ++G + + C A++P
Sbjct: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRC----FDGYRLDMTRMACVDINECDEAEAASP 1519
Query: 232 CEHNASCLEGLGSFRCLCWPGYS 254
NA CL GSFRC+C PG++
Sbjct: 1520 LCVNARCLNTDGSFRCICRPGFA 1542
Score = 42.7 bits (99), Expect = 0.002
Identities = 26/85 (30%), Positives = 30/85 (35%), Gaps = 8/85 (9%)
Query: 805 CVSEDMCSPD--PCFNGGTCLVTWNDFHCTCPANFTGPT-----CAQQLWC-PGQPCLPP 856
C D CS PC G C T F C+C + P+ CA C G C P
Sbjct: 765 CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPH 824
Query: 857 ATCEEVPDGFVCVAEATFREGPPAA 881
C F C +R GP A
Sbjct: 825 GECLNTDGSFACTCAPGYRPGPRGA 849
Score = 40.0 bits (92), Expect = 0.014
Identities = 45/147 (30%), Positives = 52/147 (35%), Gaps = 35/147 (23%)
Query: 763 FRGCLQDLRLDGCHL---PFFPLPLDNSSQPSELG---GRQSWNLTAGCVSEDMC--SPD 814
FRG + +D C P P DN++ G +S A C D C SP
Sbjct: 635 FRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPP 694
Query: 815 PCFNGGTCLVTWNDFHCTCPANFTGPT----------CAQQLWCPGQPCLPPATCEEVPD 864
PC G C T F C CP F T C L CPGQ C+ P
Sbjct: 695 PC-TYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECV------NSPG 747
Query: 865 GFVCVAEATFREGPPAAFSGHNASSGR 891
F C R P SGH+ GR
Sbjct: 748 SFQC------RTCP----SGHHLHRGR 764
Score = 39.3 bits (90), Expect = 0.025
Identities = 27/84 (32%), Positives = 34/84 (40%), Gaps = 8/84 (9%)
Query: 805 CVSEDMCS--PDPCFNGGTCLVTWNDFHCTCPANF-TGPTCAQQLWCPGQPCLPP----A 857
C+ D C P PC G C + F C C F GP A+ L +PP
Sbjct: 518 CIDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLG 576
Query: 858 TCEEVPDGFVCVAEATFREGPPAA 881
CE P F+CV A ++ P A
Sbjct: 577 RCENTPGSFLCVCPAGYQAAPHGA 600
Score = 38.9 bits (89), Expect = 0.032
Identities = 28/82 (34%), Positives = 33/82 (40%), Gaps = 8/82 (9%)
Query: 807 SEDMCSPDPCFNG-GTCLVTWNDFHCTCPANFT----GPTCAQQLWCPG--QPCLPPATC 859
S MC +P G G C+ + + C C + F G C C PC P C
Sbjct: 478 SSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAP-GRC 536
Query: 860 EEVPDGFVCVAEATFREGPPAA 881
E P F CV FR GP AA
Sbjct: 537 ENSPGSFRCVCGPGFRAGPRAA 558
Score = 38.9 bits (89), Expect = 0.032
Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 7/80 (8%)
Query: 1048 PAPILGCRGAPVCAP-SPCLHDGACRDLFDAFACACGPGWEGPRCEAH---VDPCHS--A 1101
P P GC+ C S C C++L +F C C G+EG R H V+ C +
Sbjct: 974 PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1033
Query: 1102 PCARGRCHTHPDGRFECRCP 1121
C C + +G F C CP
Sbjct: 1034 VCGAALCE-NVEGSFLCVCP 1052
Score = 38.1 bits (87), Expect = 0.055
Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 9/74 (12%)
Query: 319 VEVDECASRPCLNGGHCQDLPNGFQCHCPDGY----AGPTCEEDVDEC----LSDPCLHG 370
+E +EC G C +P GF C C DGY C D++EC + P
Sbjct: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVN 1523
Query: 371 GTCSDTVAGYICRC 384
C +T + C C
Sbjct: 1524 ARCLNTDGSFRCIC 1537
Score = 37.4 bits (85), Expect = 0.093
Identities = 23/82 (28%), Positives = 28/82 (34%), Gaps = 5/82 (6%)
Query: 805 CVSEDMC-SPDPCFNGGTCLVTWNDFHCTCPANFT----GPTCAQQLWCPGQPCLPPATC 859
C + C D CF G CL T F CTC + G +C C + C
Sbjct: 809 CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGIC 868
Query: 860 EEVPDGFVCVAEATFREGPPAA 881
F C+ R GP A
Sbjct: 869 TNTDGSFECICPPGHRAGPDLA 890
Score = 35.0 bits (79), Expect = 0.46
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 25/121 (20%)
Query: 1071 CRDLFDAFAC--ACGPGWE---GPRCEAHVDPCHSAPC--ARGRCHTHPDGRFECRCPPG 1123
C + ++ C AC PG++ G C+ VD C + A C P G F+C C G
Sbjct: 955 CENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLP-GSFQCLCDQG 1012
Query: 1124 FGGPRCRLPVPSKECSLNVTCLDGSPCE---GGSPAANCSCLEGLAGQRCQVPTLPCEAN 1180
+ G R C+D + CE G AA C +EG C P P E +
Sbjct: 1013 YEGARD-----------GRHCVDVNECETLQGVCGAALCENVEG--SFLCVCPNSPEEFD 1059
Query: 1181 P 1181
P
Sbjct: 1060 P 1060
Score = 34.3 bits (77), Expect = 0.79
Identities = 24/84 (28%), Positives = 30/84 (35%), Gaps = 8/84 (9%)
Query: 803 AGCVSEDMCSPDPCFNGGTCLVTWNDFHCTC-PANFTGPTCAQQLWCP-----GQPCLPP 856
A C+ D CS + G C T F C C P + GP A L G
Sbjct: 849 ASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS 908
Query: 857 ATCEEVPDGFVCVAEAT--FREGP 878
CE P + CV + + GP
Sbjct: 909 QRCENSPGSYRCVRDCDPGYHAGP 932
Score = 33.1 bits (74), Expect = 1.8
Identities = 12/30 (40%), Positives = 17/30 (56%), Gaps = 1/30 (3%)
Query: 805 CVSEDMCSPD-PCFNGGTCLVTWNDFHCTC 833
C+ D C+ + P GG C+ T +HCTC
Sbjct: 1227 CIDNDECADEEPACEGGRCVNTVGSYHCTC 1256
Score = 32.3 bits (72), Expect = 3.0
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 14/70 (20%)
Query: 38 PPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCV 97
P +A + D APG G GP CH+G +CV PD RC C
Sbjct: 60 PRNATSVDSGAPG--------GAAPGGPGFRAFLCPLICHNGGVCVK--PD----RCLCP 105
Query: 98 PGFQGPRCEL 107
P F G C+L
Sbjct: 106 PDFAGKFCQL 115
Score = 32.0 bits (71), Expect = 3.9
Identities = 19/65 (29%), Positives = 26/65 (40%), Gaps = 9/65 (13%)
Query: 1068 DGACRDLFDAFACACGPGWEGPRCE---AHVDPCHSAP-----CARGRCHTHPDGRFECR 1119
+G C + + F C C G+ ++ C A C RC + DG F C
Sbjct: 1478 NGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARC-LNTDGSFRCI 1536
Query: 1120 CPPGF 1124
C PGF
Sbjct: 1537 CRPGF 1541
Score = 31.2 bits (69), Expect = 6.7
Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Query: 603 CERREQCRPLPCVHG-GSCVDLWTHFRCDCARPHRGPTCADEI 644
C+ ++C P + G G+C +L FRC C RG C +++
Sbjct: 602 CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDV 644
Score = 30.8 bits (68), Expect = 8.7
Identities = 29/102 (28%), Positives = 39/102 (38%), Gaps = 21/102 (20%)
Query: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
RC G G RC + N T +D G +P G G R + L C
Sbjct: 44 RCVHGPTGSRCTPTCAPR----NATSVDSGAPGGAAP--------GGPGFRAFLCPLICH 91
Query: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCEV-AKGLPLPLP 1219
NGG C C+C F+G+FC++ + G P P
Sbjct: 92 -----NGGVCVKP---DRCLCPPDFAGKFCQLHSSGARPPAP 125
>gi|110347412 latent transforming growth factor beta binding protein
4 isoform b [Homo sapiens]
Length = 1587
Score = 175 bits (443), Expect = 3e-43
Identities = 154/460 (33%), Positives = 199/460 (43%), Gaps = 92/460 (20%)
Query: 25 PALSLLAGTVPSEPPSA-----CASDP--CAPGTECQATESGGYTCG--------PMEPR 69
P S+ A T P P S C +P C PG C + SG YTC P R
Sbjct: 490 PLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPG-RCISRPSG-YTCACDSGFRLSPQGTR 547
Query: 70 GCATQPCHH-GALCVPQGPD--PTGFRCYCVPGFQ-GPRCE--LDIDEC--ASRPCHHGA 121
C C P + P FRC C PGF+ GPR LD+DEC PC G
Sbjct: 548 CIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGR 607
Query: 122 TCRNLADRYECHCPLGYA----GVTCEMEVDECASAPCLHG-GSCLDGVGSFRCVCAPGY 176
C N + C CP GY G +C+ +VDEC +P L G G+C + GSFRCVC G+
Sbjct: 608 -CENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGF 665
Query: 177 GGTRCQLDLDECQSQPCAHG-GTCHDLVNGFRCDCAGTGYE----GTHCEREVLECASA- 230
G+ C+ D+DEC +P G G C + F C C G+ G C+ +V ECA +
Sbjct: 666 RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACP-AGFRSRGPGAPCQ-DVDECARSP 723
Query: 231 -PCEHNASCLEGLGSFRCLC----WPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALY 285
PC + C GSF+C+C P +G CE D DEC + G C+
Sbjct: 724 PPCTY-GRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNS------ 775
Query: 286 GGVQAAFPGAFSFRHAAGFLCHCPPG--FEGADCGVEVDECAS--RPCLNGGHCQDLPNG 341
PG+F R CP G C +VDEC+S PC GHC +
Sbjct: 776 -------PGSFQCR-------TCPSGHHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGS 820
Query: 342 FQCHCPDGYAGPTCE----EDVDECL-SDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQ 396
F+C C GY P+ DV+ECL D C G C +T + C C +
Sbjct: 821 FRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGY-------- 872
Query: 397 LTGCQGHTCPLAATCI--PIFESGV-----HSYVCHCPPG 429
G +G +C C + +SG+ S+ C CPPG
Sbjct: 873 RPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPG 912
Score = 162 bits (411), Expect = 1e-39
Identities = 139/447 (31%), Positives = 175/447 (39%), Gaps = 75/447 (16%)
Query: 46 PCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALC--VPQGPD-------PTGFRCYC 96
PCAPG + S CGP G C C VP D P F C C
Sbjct: 560 PCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVC 619
Query: 97 VPGFQ----GPRCELDIDECASRP--CHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC 150
G+Q G C+ D+DEC P C GA C+NL + C CP G+ G CE +VDEC
Sbjct: 620 PAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDEC 677
Query: 151 ASAPCLHG-GSCLDGVGSFRCVCAPGYG----GTRCQLDLDECQSQP--CAHGGTCHDLV 203
A P G G C + GSF C C G+ G CQ D+DEC P C +G C +
Sbjct: 678 AQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYG-RCENTE 735
Query: 204 NGFRCDCAGTGYE----GTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPG----YSG 255
F+C C G++ G+ CE +V EC + C+ GSF+C P + G
Sbjct: 736 GSFQCVCP-MGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG 793
Query: 256 ELCEVDEDECASSPCQHGGRCLQRSD----------------PALYGGVQAAFPGAFSFR 299
+VDE + PC G C P V G F F
Sbjct: 794 RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFP 853
Query: 300 HA------AGFLCHCPPGFE----GADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDG 349
H F C C PG+ GA C ++VDEC+ G C + F+C CP G
Sbjct: 854 HGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPG 912
Query: 350 Y-AGPTCEE--DVDECLS-DPCLHGG-TCSDTVAGYICRCPETWGGRDCSVQLTGCQGHT 404
+ AGP DVDEC P L G C ++ Y C RDC T
Sbjct: 913 HRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRC-------VRDCDPGYHAGPEGT 965
Query: 405 CPLAATCIPIFESGVHSYVCHCPPGTH 431
C C + C PG++
Sbjct: 966 CDDVDECQEYGPEICGAQRCENTPGSY 992
Score = 140 bits (352), Expect = 1e-32
Identities = 131/429 (30%), Positives = 176/429 (41%), Gaps = 84/429 (19%)
Query: 32 GTVPSEPPSACASDP--CAPGTECQATESGGYTC---------GPMEP----RGCATQP- 75
G+ E CA +P C PG C T +G + C GP P CA P
Sbjct: 667 GSACEEDVDECAQEPPPCGPG-RCDNT-AGSFHCACPAGFRSRGPGAPCQDVDECARSPP 724
Query: 76 -CHHGALCVPQGPDPTGFRCYCVPGFQ----GPRCELDIDECASRPCHHGATCRNLADRY 130
C +G +G F+C C GFQ G CE D+DEC + G C N +
Sbjct: 725 PCTYGRCENTEG----SFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSF 779
Query: 131 ECH-CPLGYA--GVTCEMEVDECASA--PCLHGGSCLDGVGSFRCVCAPGY----GGTRC 181
+C CP G+ C +VDEC+S PC G C + GSFRC CAPGY G
Sbjct: 780 QCRTCPSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP 838
Query: 182 QLDLDEC-QSQPCAHGGTCHDLVNGFRCDCAG---TGYEGTHCEREVLECASAPCEHNAS 237
D++EC + C G C + F C CA G G C +V EC+ +
Sbjct: 839 CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGI 897
Query: 238 CLEGLGSFRCLCWPGYSG-----ELCEVDEDE------CASSPCQHGG---RCLQRSDPA 283
C GSF C+C PG+ +VDE C S C++ RC++ DP
Sbjct: 898 CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPG 957
Query: 284 LYGGVQAAFPGAFSFRHAAGFLCH----------------CPPGFE---GADCGVEVDEC 324
+ G + + +C C PG++ G C +VDEC
Sbjct: 958 YHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDEC 1016
Query: 325 ASRPCLNGGH--CQDLPNGFQCHCPDGYAGPTCEE---DVDECLSDPCLHGGTCSDTVAG 379
+R G H CQ+LP FQC C GY G DV+EC + + G + V G
Sbjct: 1017 RNRSFC-GAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEG 1075
Query: 380 -YICRCPET 387
++C CP +
Sbjct: 1076 SFLCVCPNS 1084
Score = 115 bits (288), Expect = 3e-25
Identities = 92/279 (32%), Positives = 118/279 (42%), Gaps = 66/279 (23%)
Query: 188 CQSQPCAHG-GTCHDLVNGFRCDCAGTGY----EGTHCEREVLECASAP--CEHNASCLE 240
CQ P G G C +G+ C C +G+ +GT C +V EC P C C
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCAC-DSGFRLSPQGTRCI-DVDECRRVPPPCAPGR-CEN 568
Query: 241 GLGSFRCLCWPGY-----SGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGA 295
GSFRC+C PG+ + E +VDE PC G RC PG+
Sbjct: 569 SPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLG-RCENT-------------PGS 614
Query: 296 FSFRHAAGFLCHCPPGFEGADCGV---EVDECASRPCLNG-GHCQDLPNGFQCHCPDGYA 351
F LC CP G++ A G +VDEC P L G G C++LP F+C CP G+
Sbjct: 615 F--------LCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR 666
Query: 352 GPTCEEDVDECLSDPCLHG-GTCSDTVAGYICRCPETWGGR----------DCSVQLTGC 400
G CEEDVDEC +P G G C +T + C CP + R +C+ C
Sbjct: 667 GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC 726
Query: 401 QGHTCPLAATCIPIFESGVHSYVCHCP----PGTHGPFC 435
C E+ S+ C CP P T G C
Sbjct: 727 TYGRC----------ENTEGSFQCVCPMGFQPNTAGSEC 755
Score = 103 bits (258), Expect = 8e-22
Identities = 130/506 (25%), Positives = 169/506 (33%), Gaps = 147/506 (29%)
Query: 46 PCAPGTECQATESG-------GYTCGPMEPRGCA-TQPCHHGALCVPQGP---DPTGFRC 94
PC P C TE GY P CA C G C P G F C
Sbjct: 807 PCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFAC 866
Query: 95 YCVPGFQ-GPRCE--LDIDECASRPCHHGATCRNLADRYECHCPLGYAG----VTCEMEV 147
C PG++ GPR LD+DEC+ C N +EC CP G+ +C ++V
Sbjct: 867 TCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-LDV 925
Query: 148 DECAS-APCLHGGS-CLDGVGSFRCV--CAPGY----------------------GGTRC 181
DEC P L G C + GS+RCV C PGY G RC
Sbjct: 926 DECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRC 985
Query: 182 Q------------------------LDLDECQSQP-CAHGGTCHDLVNGFRCDCAGTGYE 216
+ D+DEC+++ C C +L F+C C GYE
Sbjct: 986 ENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLC-DQGYE 1044
Query: 217 GT----HCEREVLECASAPCEHNASCLEGL-GSFRCLCW---------------PGYSGE 256
G HC +V EC + A+ E + GSF C+C P S
Sbjct: 1045 GARDGRHCV-DVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAG 1103
Query: 257 LCEVDEDECASSPCQHGGR---------CLQRSDPALYGGVQAAFPGA-------FSFRH 300
+ + +SP R P G + F A R+
Sbjct: 1104 TFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARN 1163
Query: 301 AAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDG--YAGPTCE-- 356
C C G EG G + +C +Q CP G Y P+ +
Sbjct: 1164 VTWQECCCTVG-EGWGSGCRIQQCPGTETAE----------YQSLCPHGRGYLAPSGDLS 1212
Query: 357 --EDVDEC--LSDPCLHGGTCSDTVAGYICRCP----------ETWGGRDCSVQLTGCQG 402
DVDEC D G C +T GY C C E +C+ + C+G
Sbjct: 1213 LRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG 1272
Query: 403 HTCPLAATCIPIFESGVHSYVCHCPP 428
C + V SY C C P
Sbjct: 1273 GRC----------VNTVGSYHCTCEP 1288
Score = 81.6 bits (200), Expect = 4e-15
Identities = 73/219 (33%), Positives = 85/219 (38%), Gaps = 34/219 (15%)
Query: 1016 RVALGGLPL----PLARPRPGAAPGAREHFAS---WPGTPAPILG-----CRGAP-VCAP 1062
R + G LP P PRP PG S W G P G C+ P VC P
Sbjct: 462 RPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGP 521
Query: 1063 SPCLHDGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAP--CARGRCHTHPDGRF 1116
C+ + + CAC G+ +G RC VD C P CA GRC P G F
Sbjct: 522 GRCISRPS------GYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGRCENSP-GSF 573
Query: 1117 ECRCPPGF-GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLA----GQRCQ 1171
C C PGF GPR + EC D CE + C C G G CQ
Sbjct: 574 RCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ 633
Query: 1172 VPTLPCEANPCLNG-GTCRAAGGVSECICNARFSGQFCE 1209
C +P L G G C+ G C+C A F G CE
Sbjct: 634 -DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACE 671
Score = 81.3 bits (199), Expect = 6e-15
Identities = 117/453 (25%), Positives = 158/453 (34%), Gaps = 96/453 (21%)
Query: 42 CASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQ 101
CAS T+ G G + + C+ + + + P GP PTGF
Sbjct: 261 CASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERV------ 314
Query: 102 GPRCELDIDECASRP-CHHGATCRNLADRYECHCPLGY----AGVTC-EMEVDECASAPC 155
CE D+DECA+ C HG C N Y C CP G+ + +C V A PC
Sbjct: 315 NGSCE-DVDECATGGRCQHGE-CANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC 372
Query: 156 ---LHGGSC----LDGVGSFRCVC-----APGYGGTRCQLDLDECQSQPCAHGGTCHDLV 203
L G C L + C C A G G C E + C G H
Sbjct: 373 FRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSA 432
Query: 204 NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLG---------------SFRCL 248
+ R + G E A +A L
Sbjct: 433 SDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLP 492
Query: 249 CWPGYSGELCEVDEDECASSPCQHG------GRCLQRSDPALYGGVQAAFPGAFSFRHAA 302
P ++G E+ E +S CQ GRC+ R +
Sbjct: 493 SIPAWTGP--EIPESGPSSGMCQRNPQVCGPGRCISRP---------------------S 529
Query: 303 GFLCHCPPGF----EGADCGVEVDEC--ASRPCLNGGHCQDLPNGFQCHCPDGY-AGPTC 355
G+ C C GF +G C ++VDEC PC G C++ P F+C C G+ AGP
Sbjct: 530 GYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRA 587
Query: 356 EE--DVDEC--LSDPCLHGGTCSDTVAGYICRCPETWG----GRDCSV--QLTGCQGHTC 405
E DVDEC + PC G C +T ++C CP + G C + T G
Sbjct: 588 AECLDVDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCG 646
Query: 406 PLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438
A +P S+ C CP G G C ++
Sbjct: 647 RGACKNLP------GSFRCVCPAGFRGSACEED 673
Score = 67.8 bits (164), Expect = 6e-11
Identities = 48/152 (31%), Positives = 61/152 (40%), Gaps = 10/152 (6%)
Query: 1054 CRGAPVCAPSPCLHD-GACRDLFDAFACACGPGWEGPRCEAHVDPC--HSAPCARGRCHT 1110
C+ C SP L GAC++L +F C C G+ G CE VD C PC GRC
Sbjct: 632 CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRC-D 690
Query: 1111 HPDGRFECRCPPGFGGPRCRLPVPS-KECSLNVTCLDGSPCEGGSPAANCSCLEGL---- 1165
+ G F C CP GF P EC+ + CE + C C G
Sbjct: 691 NTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNT 750
Query: 1166 AGQRCQVPTLPCEANPCLNGGTCRAAGGVSEC 1197
AG C+ CE + G C + G +C
Sbjct: 751 AGSECE-DVDECENHLACPGQECVNSPGSFQC 781
Score = 58.2 bits (139), Expect = 5e-08
Identities = 48/136 (35%), Positives = 57/136 (41%), Gaps = 13/136 (9%)
Query: 1030 RPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWE-G 1088
R APG R + PG A + C C P G C + +FAC C PG+ G
Sbjct: 822 RCSCAPGYRAP-SGRPGPCADVNECLEGDFCFPH-----GECLNTDGSFACTCAPGYRPG 875
Query: 1089 PRCEA--HVDPCHSAP-CARGRCHTHPDGRFECRCPPGF-GGPRCRLPVPSKECSLNVTC 1144
PR + VD C C G C T+ DG FEC CPPG GP + EC
Sbjct: 876 PRGASCLDVDECSEEDLCQSGIC-TNTDGSFECICPPGHRAGPDLASCLDVDECRERGPA 934
Query: 1145 LDGSP-CEGGSPAANC 1159
L GS CE + C
Sbjct: 935 LCGSQRCENSPGSYRC 950
Score = 57.8 bits (138), Expect = 7e-08
Identities = 54/178 (30%), Positives = 70/178 (39%), Gaps = 28/178 (15%)
Query: 24 APALSLLAGTVPSEP----PSACASDPCAPGT-ECQATESGGYTCGPMEPRGCATQPC-- 76
APA +L P P PS P G EC + C + R Q C
Sbjct: 1112 APASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCC 1171
Query: 77 ----HHGALCVPQ---GPDPTGFRCYCVPG--FQGPRCEL----DIDECA---SRPCHHG 120
G+ C Q G + ++ C G + P +L D+DEC + C G
Sbjct: 1172 TVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSG 1231
Query: 121 ATCRNLADRYECHCPLGYAGVTCEMEV---DECASA-PCLHGGSCLDGVGSFRCVCAP 174
C N A Y C+C GY T +E DECA P GG C++ VGS+ C C P
Sbjct: 1232 V-CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1288
Score = 53.9 bits (128), Expect = 1e-06
Identities = 50/169 (29%), Positives = 63/169 (37%), Gaps = 23/169 (13%)
Query: 1045 PGTPAPILGCRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE----GPRCEAHVDPC 1098
PG P C+ CA P PC + G C + +F C C G++ G CE VD C
Sbjct: 709 PGAP-----CQDVDECARSPPPCTY-GRCENTEGSFQCVCPMGFQPNTAGSECE-DVDEC 761
Query: 1099 HSAPCARGRCHTHPDGRFECR-CPPGFGGPRCRLPVPSKECSLNV-TCLDGSPCEGGSPA 1156
+ G+ + G F+CR CP G R R ECS C C +
Sbjct: 762 ENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGS 820
Query: 1157 ANCSCLEGLAGQRCQVPTLPCEANPCLNG------GTCRAAGGVSECIC 1199
CSC G + P + N CL G G C G C C
Sbjct: 821 FRCSCAPGYRAPSGR-PGPCADVNECLEGDFCFPHGECLNTDGSFACTC 868
Score = 52.4 bits (124), Expect = 3e-06
Identities = 50/167 (29%), Positives = 62/167 (37%), Gaps = 33/167 (19%)
Query: 1056 GAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSA-PCARGR-CHTH-- 1111
GAP C P G C + +F C+C PG+ P PC C G C H
Sbjct: 804 GAPPCGPH-----GHCTNTEGSFRCSCAPGYRAP--SGRPGPCADVNECLEGDFCFPHGE 856
Query: 1112 ---PDGRFECRCPPGF-GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEG-LA 1166
DG F C C PG+ GPR + ECS C G C + C C G A
Sbjct: 857 CLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGI-CTNTDGSFECICPPGHRA 915
Query: 1167 GQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKG 1213
G + CL+ CR G +C + Q CE + G
Sbjct: 916 GP---------DLASCLDVDECRERG---PALCGS----QRCENSPG 946
Score = 45.8 bits (107), Expect = 3e-04
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 9/85 (10%)
Query: 103 PRCELDIDECASRPCHHGATCRNLADRYECHCPLGY----AGVTCEMEVDEC----ASAP 154
P EL+ +EC C + + + C C GY + C ++++EC A++P
Sbjct: 1491 PYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASP 1549
Query: 155 CLHGGSCLDGVGSFRCVCAPGYGGT 179
CL+ GSFRC+C PG+ T
Sbjct: 1550 LCVNARCLNTDGSFRCICRPGFAPT 1574
Score = 45.4 bits (106), Expect = 3e-04
Identities = 26/82 (31%), Positives = 30/82 (36%), Gaps = 3/82 (3%)
Query: 803 AGCVSEDMCSPDPCFNG-GTCLVTWNDFHCTCPANFTGPTCAQQL--WCPGQPCLPPATC 859
A C D C+ P G G C F C CPA F G C + + P P C
Sbjct: 630 ASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRC 689
Query: 860 EEVPDGFVCVAEATFREGPPAA 881
+ F C A FR P A
Sbjct: 690 DNTAGSFHCACPAGFRSRGPGA 711
Score = 44.7 bits (104), Expect = 6e-04
Identities = 65/267 (24%), Positives = 85/267 (31%), Gaps = 41/267 (15%)
Query: 135 PLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCA 194
P G A V C + C +GG C V RC+C P + G CQL + A
Sbjct: 108 PAGKAPVLCPLI--------CHNGGVC---VKPDRCLCPPDFAGKFCQLHSSGARPPAPA 156
Query: 195 HGGTCHDLVN----GFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCW 250
G + R D E V S EH + +
Sbjct: 157 VPGLTRSVYTMPLANHRDD-----------EHGVASMVSVHVEHPQEASVVVHQVERVSG 205
Query: 251 PGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCP- 309
P + V E A+ + G A + FR G C P
Sbjct: 206 PWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPL 265
Query: 310 PGFE-------GADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHCPDGY--AGPTCEEDV 359
PG GA V +C L P+G CP G+ +CE DV
Sbjct: 266 PGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDG---PCPTGFERVNGSCE-DV 321
Query: 360 DECLSDPCLHGGTCSDTVAGYICRCPE 386
DEC + G C++T GY C CP+
Sbjct: 322 DECATGGRCQHGECANTRGGYTCVCPD 348
Score = 43.5 bits (101), Expect = 0.001
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 14/83 (16%)
Query: 182 QLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLEC----------ASAP 231
+L+ +EC G C + GF C C ++G + + C A++P
Sbjct: 1494 ELEAEECGILDGCTNGRCVRVPEGFTCRC----FDGYRLDMTRMACVDINECDEAEAASP 1549
Query: 232 CEHNASCLEGLGSFRCLCWPGYS 254
NA CL GSFRC+C PG++
Sbjct: 1550 LCVNARCLNTDGSFRCICRPGFA 1572
Score = 42.7 bits (99), Expect = 0.002
Identities = 26/85 (30%), Positives = 30/85 (35%), Gaps = 8/85 (9%)
Query: 805 CVSEDMCSPD--PCFNGGTCLVTWNDFHCTCPANFTGPT-----CAQQLWC-PGQPCLPP 856
C D CS PC G C T F C+C + P+ CA C G C P
Sbjct: 795 CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPH 854
Query: 857 ATCEEVPDGFVCVAEATFREGPPAA 881
C F C +R GP A
Sbjct: 855 GECLNTDGSFACTCAPGYRPGPRGA 879
Score = 40.0 bits (92), Expect = 0.014
Identities = 45/147 (30%), Positives = 52/147 (35%), Gaps = 35/147 (23%)
Query: 763 FRGCLQDLRLDGCHL---PFFPLPLDNSSQPSELG---GRQSWNLTAGCVSEDMC--SPD 814
FRG + +D C P P DN++ G +S A C D C SP
Sbjct: 665 FRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPP 724
Query: 815 PCFNGGTCLVTWNDFHCTCPANFTGPT----------CAQQLWCPGQPCLPPATCEEVPD 864
PC G C T F C CP F T C L CPGQ C+ P
Sbjct: 725 PC-TYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECV------NSPG 777
Query: 865 GFVCVAEATFREGPPAAFSGHNASSGR 891
F C R P SGH+ GR
Sbjct: 778 SFQC------RTCP----SGHHLHRGR 794
Score = 39.3 bits (90), Expect = 0.025
Identities = 27/84 (32%), Positives = 34/84 (40%), Gaps = 8/84 (9%)
Query: 805 CVSEDMCS--PDPCFNGGTCLVTWNDFHCTCPANF-TGPTCAQQLWCPGQPCLPP----A 857
C+ D C P PC G C + F C C F GP A+ L +PP
Sbjct: 548 CIDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLG 606
Query: 858 TCEEVPDGFVCVAEATFREGPPAA 881
CE P F+CV A ++ P A
Sbjct: 607 RCENTPGSFLCVCPAGYQAAPHGA 630
Score = 38.9 bits (89), Expect = 0.032
Identities = 28/82 (34%), Positives = 33/82 (40%), Gaps = 8/82 (9%)
Query: 807 SEDMCSPDPCFNG-GTCLVTWNDFHCTCPANFT----GPTCAQQLWCPG--QPCLPPATC 859
S MC +P G G C+ + + C C + F G C C PC P C
Sbjct: 508 SSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAP-GRC 566
Query: 860 EEVPDGFVCVAEATFREGPPAA 881
E P F CV FR GP AA
Sbjct: 567 ENSPGSFRCVCGPGFRAGPRAA 588
Score = 38.9 bits (89), Expect = 0.032
Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 7/80 (8%)
Query: 1048 PAPILGCRGAPVCAP-SPCLHDGACRDLFDAFACACGPGWEGPRCEAH---VDPCHS--A 1101
P P GC+ C S C C++L +F C C G+EG R H V+ C +
Sbjct: 1004 PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1063
Query: 1102 PCARGRCHTHPDGRFECRCP 1121
C C + +G F C CP
Sbjct: 1064 VCGAALCE-NVEGSFLCVCP 1082
Score = 38.1 bits (87), Expect = 0.055
Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 9/74 (12%)
Query: 319 VEVDECASRPCLNGGHCQDLPNGFQCHCPDGY----AGPTCEEDVDEC----LSDPCLHG 370
+E +EC G C +P GF C C DGY C D++EC + P
Sbjct: 1495 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVN 1553
Query: 371 GTCSDTVAGYICRC 384
C +T + C C
Sbjct: 1554 ARCLNTDGSFRCIC 1567
Score = 37.4 bits (85), Expect = 0.093
Identities = 23/82 (28%), Positives = 28/82 (34%), Gaps = 5/82 (6%)
Query: 805 CVSEDMC-SPDPCFNGGTCLVTWNDFHCTCPANFT----GPTCAQQLWCPGQPCLPPATC 859
C + C D CF G CL T F CTC + G +C C + C
Sbjct: 839 CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGIC 898
Query: 860 EEVPDGFVCVAEATFREGPPAA 881
F C+ R GP A
Sbjct: 899 TNTDGSFECICPPGHRAGPDLA 920
Score = 35.0 bits (79), Expect = 0.46
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 25/121 (20%)
Query: 1071 CRDLFDAFAC--ACGPGWE---GPRCEAHVDPCHSAPC--ARGRCHTHPDGRFECRCPPG 1123
C + ++ C AC PG++ G C+ VD C + A C P G F+C C G
Sbjct: 985 CENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLP-GSFQCLCDQG 1042
Query: 1124 FGGPRCRLPVPSKECSLNVTCLDGSPCE---GGSPAANCSCLEGLAGQRCQVPTLPCEAN 1180
+ G R C+D + CE G AA C +EG C P P E +
Sbjct: 1043 YEGARD-----------GRHCVDVNECETLQGVCGAALCENVEG--SFLCVCPNSPEEFD 1089
Query: 1181 P 1181
P
Sbjct: 1090 P 1090
Score = 34.3 bits (77), Expect = 0.79
Identities = 24/84 (28%), Positives = 30/84 (35%), Gaps = 8/84 (9%)
Query: 803 AGCVSEDMCSPDPCFNGGTCLVTWNDFHCTC-PANFTGPTCAQQLWCP-----GQPCLPP 856
A C+ D CS + G C T F C C P + GP A L G
Sbjct: 879 ASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS 938
Query: 857 ATCEEVPDGFVCVAEAT--FREGP 878
CE P + CV + + GP
Sbjct: 939 QRCENSPGSYRCVRDCDPGYHAGP 962
Score = 33.1 bits (74), Expect = 1.8
Identities = 12/30 (40%), Positives = 17/30 (56%), Gaps = 1/30 (3%)
Query: 805 CVSEDMCSPD-PCFNGGTCLVTWNDFHCTC 833
C+ D C+ + P GG C+ T +HCTC
Sbjct: 1257 CIDNDECADEEPACEGGRCVNTVGSYHCTC 1286
Score = 32.0 bits (71), Expect = 3.9
Identities = 19/65 (29%), Positives = 26/65 (40%), Gaps = 9/65 (13%)
Query: 1068 DGACRDLFDAFACACGPGWEGPRCE---AHVDPCHSAP-----CARGRCHTHPDGRFECR 1119
+G C + + F C C G+ ++ C A C RC + DG F C
Sbjct: 1508 NGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARC-LNTDGSFRCI 1566
Query: 1120 CPPGF 1124
C PGF
Sbjct: 1567 CRPGF 1571
Score = 31.6 bits (70), Expect = 5.1
Identities = 15/32 (46%), Positives = 18/32 (56%), Gaps = 6/32 (18%)
Query: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCEL 107
CH+G +CV PD RC C P F G C+L
Sbjct: 120 CHNGGVCVK--PD----RCLCPPDFAGKFCQL 145
Score = 31.2 bits (69), Expect = 6.7
Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Query: 603 CERREQCRPLPCVHG-GSCVDLWTHFRCDCARPHRGPTCADEI 644
C+ ++C P + G G+C +L FRC C RG C +++
Sbjct: 632 CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDV 674
>gi|110347431 latent transforming growth factor beta binding protein
4 isoform a [Homo sapiens]
Length = 1624
Score = 175 bits (443), Expect = 3e-43
Identities = 154/460 (33%), Positives = 199/460 (43%), Gaps = 92/460 (20%)
Query: 25 PALSLLAGTVPSEPPSA-----CASDP--CAPGTECQATESGGYTCG--------PMEPR 69
P S+ A T P P S C +P C PG C + SG YTC P R
Sbjct: 527 PLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPG-RCISRPSG-YTCACDSGFRLSPQGTR 584
Query: 70 GCATQPCHH-GALCVPQGPD--PTGFRCYCVPGFQ-GPRCE--LDIDEC--ASRPCHHGA 121
C C P + P FRC C PGF+ GPR LD+DEC PC G
Sbjct: 585 CIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGR 644
Query: 122 TCRNLADRYECHCPLGYA----GVTCEMEVDECASAPCLHG-GSCLDGVGSFRCVCAPGY 176
C N + C CP GY G +C+ +VDEC +P L G G+C + GSFRCVC G+
Sbjct: 645 -CENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGF 702
Query: 177 GGTRCQLDLDECQSQPCAHG-GTCHDLVNGFRCDCAGTGYE----GTHCEREVLECASA- 230
G+ C+ D+DEC +P G G C + F C C G+ G C+ +V ECA +
Sbjct: 703 RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACP-AGFRSRGPGAPCQ-DVDECARSP 760
Query: 231 -PCEHNASCLEGLGSFRCLC----WPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALY 285
PC + C GSF+C+C P +G CE D DEC + G C+
Sbjct: 761 PPCTY-GRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNS------ 812
Query: 286 GGVQAAFPGAFSFRHAAGFLCHCPPG--FEGADCGVEVDECAS--RPCLNGGHCQDLPNG 341
PG+F R CP G C +VDEC+S PC GHC +
Sbjct: 813 -------PGSFQCR-------TCPSGHHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGS 857
Query: 342 FQCHCPDGYAGPTCE----EDVDECL-SDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQ 396
F+C C GY P+ DV+ECL D C G C +T + C C +
Sbjct: 858 FRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGY-------- 909
Query: 397 LTGCQGHTCPLAATCI--PIFESGV-----HSYVCHCPPG 429
G +G +C C + +SG+ S+ C CPPG
Sbjct: 910 RPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPG 949
Score = 162 bits (411), Expect = 1e-39
Identities = 139/447 (31%), Positives = 175/447 (39%), Gaps = 75/447 (16%)
Query: 46 PCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALC--VPQGPD-------PTGFRCYC 96
PCAPG + S CGP G C C VP D P F C C
Sbjct: 597 PCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVC 656
Query: 97 VPGFQ----GPRCELDIDECASRP--CHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC 150
G+Q G C+ D+DEC P C GA C+NL + C CP G+ G CE +VDEC
Sbjct: 657 PAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDEC 714
Query: 151 ASAPCLHG-GSCLDGVGSFRCVCAPGYG----GTRCQLDLDECQSQP--CAHGGTCHDLV 203
A P G G C + GSF C C G+ G CQ D+DEC P C +G C +
Sbjct: 715 AQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYG-RCENTE 772
Query: 204 NGFRCDCAGTGYE----GTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPG----YSG 255
F+C C G++ G+ CE +V EC + C+ GSF+C P + G
Sbjct: 773 GSFQCVCP-MGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG 830
Query: 256 ELCEVDEDECASSPCQHGGRCLQRSD----------------PALYGGVQAAFPGAFSFR 299
+VDE + PC G C P V G F F
Sbjct: 831 RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFP 890
Query: 300 HA------AGFLCHCPPGFE----GADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDG 349
H F C C PG+ GA C ++VDEC+ G C + F+C CP G
Sbjct: 891 HGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPG 949
Query: 350 Y-AGPTCEE--DVDECLS-DPCLHGG-TCSDTVAGYICRCPETWGGRDCSVQLTGCQGHT 404
+ AGP DVDEC P L G C ++ Y C RDC T
Sbjct: 950 HRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRC-------VRDCDPGYHAGPEGT 1002
Query: 405 CPLAATCIPIFESGVHSYVCHCPPGTH 431
C C + C PG++
Sbjct: 1003 CDDVDECQEYGPEICGAQRCENTPGSY 1029
Score = 140 bits (352), Expect = 1e-32
Identities = 131/429 (30%), Positives = 176/429 (41%), Gaps = 84/429 (19%)
Query: 32 GTVPSEPPSACASDP--CAPGTECQATESGGYTC---------GPMEP----RGCATQP- 75
G+ E CA +P C PG C T +G + C GP P CA P
Sbjct: 704 GSACEEDVDECAQEPPPCGPG-RCDNT-AGSFHCACPAGFRSRGPGAPCQDVDECARSPP 761
Query: 76 -CHHGALCVPQGPDPTGFRCYCVPGFQ----GPRCELDIDECASRPCHHGATCRNLADRY 130
C +G +G F+C C GFQ G CE D+DEC + G C N +
Sbjct: 762 PCTYGRCENTEG----SFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSF 816
Query: 131 ECH-CPLGYA--GVTCEMEVDECASA--PCLHGGSCLDGVGSFRCVCAPGY----GGTRC 181
+C CP G+ C +VDEC+S PC G C + GSFRC CAPGY G
Sbjct: 817 QCRTCPSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP 875
Query: 182 QLDLDEC-QSQPCAHGGTCHDLVNGFRCDCAG---TGYEGTHCEREVLECASAPCEHNAS 237
D++EC + C G C + F C CA G G C +V EC+ +
Sbjct: 876 CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGI 934
Query: 238 CLEGLGSFRCLCWPGYSG-----ELCEVDEDE------CASSPCQHGG---RCLQRSDPA 283
C GSF C+C PG+ +VDE C S C++ RC++ DP
Sbjct: 935 CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPG 994
Query: 284 LYGGVQAAFPGAFSFRHAAGFLCH----------------CPPGFE---GADCGVEVDEC 324
+ G + + +C C PG++ G C +VDEC
Sbjct: 995 YHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDEC 1053
Query: 325 ASRPCLNGGH--CQDLPNGFQCHCPDGYAGPTCEE---DVDECLSDPCLHGGTCSDTVAG 379
+R G H CQ+LP FQC C GY G DV+EC + + G + V G
Sbjct: 1054 RNRSFC-GAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEG 1112
Query: 380 -YICRCPET 387
++C CP +
Sbjct: 1113 SFLCVCPNS 1121
Score = 115 bits (288), Expect = 3e-25
Identities = 92/279 (32%), Positives = 118/279 (42%), Gaps = 66/279 (23%)
Query: 188 CQSQPCAHG-GTCHDLVNGFRCDCAGTGY----EGTHCEREVLECASAP--CEHNASCLE 240
CQ P G G C +G+ C C +G+ +GT C +V EC P C C
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCAC-DSGFRLSPQGTRCI-DVDECRRVPPPCAPGR-CEN 605
Query: 241 GLGSFRCLCWPGY-----SGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGA 295
GSFRC+C PG+ + E +VDE PC G RC PG+
Sbjct: 606 SPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLG-RCENT-------------PGS 651
Query: 296 FSFRHAAGFLCHCPPGFEGADCGV---EVDECASRPCLNG-GHCQDLPNGFQCHCPDGYA 351
F LC CP G++ A G +VDEC P L G G C++LP F+C CP G+
Sbjct: 652 F--------LCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR 703
Query: 352 GPTCEEDVDECLSDPCLHG-GTCSDTVAGYICRCPETWGGR----------DCSVQLTGC 400
G CEEDVDEC +P G G C +T + C CP + R +C+ C
Sbjct: 704 GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC 763
Query: 401 QGHTCPLAATCIPIFESGVHSYVCHCP----PGTHGPFC 435
C E+ S+ C CP P T G C
Sbjct: 764 TYGRC----------ENTEGSFQCVCPMGFQPNTAGSEC 792
Score = 103 bits (258), Expect = 8e-22
Identities = 130/506 (25%), Positives = 169/506 (33%), Gaps = 147/506 (29%)
Query: 46 PCAPGTECQATESG-------GYTCGPMEPRGCA-TQPCHHGALCVPQGP---DPTGFRC 94
PC P C TE GY P CA C G C P G F C
Sbjct: 844 PCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFAC 903
Query: 95 YCVPGFQ-GPRCE--LDIDECASRPCHHGATCRNLADRYECHCPLGYAG----VTCEMEV 147
C PG++ GPR LD+DEC+ C N +EC CP G+ +C ++V
Sbjct: 904 TCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-LDV 962
Query: 148 DECAS-APCLHGGS-CLDGVGSFRCV--CAPGY----------------------GGTRC 181
DEC P L G C + GS+RCV C PGY G RC
Sbjct: 963 DECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRC 1022
Query: 182 Q------------------------LDLDECQSQP-CAHGGTCHDLVNGFRCDCAGTGYE 216
+ D+DEC+++ C C +L F+C C GYE
Sbjct: 1023 ENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLC-DQGYE 1081
Query: 217 GT----HCEREVLECASAPCEHNASCLEGL-GSFRCLCW---------------PGYSGE 256
G HC +V EC + A+ E + GSF C+C P S
Sbjct: 1082 GARDGRHCV-DVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAG 1140
Query: 257 LCEVDEDECASSPCQHGGR---------CLQRSDPALYGGVQAAFPGA-------FSFRH 300
+ + +SP R P G + F A R+
Sbjct: 1141 TFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARN 1200
Query: 301 AAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDG--YAGPTCE-- 356
C C G EG G + +C +Q CP G Y P+ +
Sbjct: 1201 VTWQECCCTVG-EGWGSGCRIQQCPGTETAE----------YQSLCPHGRGYLAPSGDLS 1249
Query: 357 --EDVDEC--LSDPCLHGGTCSDTVAGYICRCP----------ETWGGRDCSVQLTGCQG 402
DVDEC D G C +T GY C C E +C+ + C+G
Sbjct: 1250 LRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG 1309
Query: 403 HTCPLAATCIPIFESGVHSYVCHCPP 428
C + V SY C C P
Sbjct: 1310 GRC----------VNTVGSYHCTCEP 1325
Score = 81.6 bits (200), Expect = 4e-15
Identities = 73/219 (33%), Positives = 85/219 (38%), Gaps = 34/219 (15%)
Query: 1016 RVALGGLPL----PLARPRPGAAPGAREHFAS---WPGTPAPILG-----CRGAP-VCAP 1062
R + G LP P PRP PG S W G P G C+ P VC P
Sbjct: 499 RPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGP 558
Query: 1063 SPCLHDGACRDLFDAFACACGPGW----EGPRCEAHVDPCHSAP--CARGRCHTHPDGRF 1116
C+ + + CAC G+ +G RC VD C P CA GRC P G F
Sbjct: 559 GRCISRPS------GYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGRCENSP-GSF 610
Query: 1117 ECRCPPGF-GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLA----GQRCQ 1171
C C PGF GPR + EC D CE + C C G G CQ
Sbjct: 611 RCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ 670
Query: 1172 VPTLPCEANPCLNG-GTCRAAGGVSECICNARFSGQFCE 1209
C +P L G G C+ G C+C A F G CE
Sbjct: 671 -DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACE 708
Score = 81.3 bits (199), Expect = 6e-15
Identities = 117/453 (25%), Positives = 158/453 (34%), Gaps = 96/453 (21%)
Query: 42 CASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQ 101
CAS T+ G G + + C+ + + + P GP PTGF
Sbjct: 298 CASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERV------ 351
Query: 102 GPRCELDIDECASRP-CHHGATCRNLADRYECHCPLGY----AGVTC-EMEVDECASAPC 155
CE D+DECA+ C HG C N Y C CP G+ + +C V A PC
Sbjct: 352 NGSCE-DVDECATGGRCQHGE-CANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC 409
Query: 156 ---LHGGSC----LDGVGSFRCVC-----APGYGGTRCQLDLDECQSQPCAHGGTCHDLV 203
L G C L + C C A G G C E + C G H
Sbjct: 410 FRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSA 469
Query: 204 NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLG---------------SFRCL 248
+ R + G E A +A L
Sbjct: 470 SDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLP 529
Query: 249 CWPGYSGELCEVDEDECASSPCQHG------GRCLQRSDPALYGGVQAAFPGAFSFRHAA 302
P ++G E+ E +S CQ GRC+ R +
Sbjct: 530 SIPAWTGP--EIPESGPSSGMCQRNPQVCGPGRCISRP---------------------S 566
Query: 303 GFLCHCPPGF----EGADCGVEVDEC--ASRPCLNGGHCQDLPNGFQCHCPDGY-AGPTC 355
G+ C C GF +G C ++VDEC PC G C++ P F+C C G+ AGP
Sbjct: 567 GYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRA 624
Query: 356 EE--DVDEC--LSDPCLHGGTCSDTVAGYICRCPETWG----GRDCSV--QLTGCQGHTC 405
E DVDEC + PC G C +T ++C CP + G C + T G
Sbjct: 625 AECLDVDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCG 683
Query: 406 PLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438
A +P S+ C CP G G C ++
Sbjct: 684 RGACKNLP------GSFRCVCPAGFRGSACEED 710
Score = 67.8 bits (164), Expect = 6e-11
Identities = 48/152 (31%), Positives = 61/152 (40%), Gaps = 10/152 (6%)
Query: 1054 CRGAPVCAPSPCLHD-GACRDLFDAFACACGPGWEGPRCEAHVDPC--HSAPCARGRCHT 1110
C+ C SP L GAC++L +F C C G+ G CE VD C PC GRC
Sbjct: 669 CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRC-D 727
Query: 1111 HPDGRFECRCPPGFGGPRCRLPVPS-KECSLNVTCLDGSPCEGGSPAANCSCLEGL---- 1165
+ G F C CP GF P EC+ + CE + C C G
Sbjct: 728 NTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNT 787
Query: 1166 AGQRCQVPTLPCEANPCLNGGTCRAAGGVSEC 1197
AG C+ CE + G C + G +C
Sbjct: 788 AGSECE-DVDECENHLACPGQECVNSPGSFQC 818
Score = 58.2 bits (139), Expect = 5e-08
Identities = 48/136 (35%), Positives = 57/136 (41%), Gaps = 13/136 (9%)
Query: 1030 RPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWE-G 1088
R APG R + PG A + C C P G C + +FAC C PG+ G
Sbjct: 859 RCSCAPGYRAP-SGRPGPCADVNECLEGDFCFPH-----GECLNTDGSFACTCAPGYRPG 912
Query: 1089 PRCEA--HVDPCHSAP-CARGRCHTHPDGRFECRCPPGF-GGPRCRLPVPSKECSLNVTC 1144
PR + VD C C G C T+ DG FEC CPPG GP + EC
Sbjct: 913 PRGASCLDVDECSEEDLCQSGIC-TNTDGSFECICPPGHRAGPDLASCLDVDECRERGPA 971
Query: 1145 LDGSP-CEGGSPAANC 1159
L GS CE + C
Sbjct: 972 LCGSQRCENSPGSYRC 987
Score = 57.8 bits (138), Expect = 7e-08
Identities = 54/178 (30%), Positives = 70/178 (39%), Gaps = 28/178 (15%)
Query: 24 APALSLLAGTVPSEP----PSACASDPCAPGT-ECQATESGGYTCGPMEPRGCATQPC-- 76
APA +L P P PS P G EC + C + R Q C
Sbjct: 1149 APASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCC 1208
Query: 77 ----HHGALCVPQ---GPDPTGFRCYCVPG--FQGPRCEL----DIDECA---SRPCHHG 120
G+ C Q G + ++ C G + P +L D+DEC + C G
Sbjct: 1209 TVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSG 1268
Query: 121 ATCRNLADRYECHCPLGYAGVTCEMEV---DECASA-PCLHGGSCLDGVGSFRCVCAP 174
C N A Y C+C GY T +E DECA P GG C++ VGS+ C C P
Sbjct: 1269 V-CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1325
Score = 56.6 bits (135), Expect = 1e-07
Identities = 103/413 (24%), Positives = 140/413 (33%), Gaps = 57/413 (13%)
Query: 3 LARPGTPDPQALASVLLLLLWAPALSLLAGT--------VPSEP--PSACASDPCAPGTE 52
+ RPGT + L VLLL L+A A S + + VP P P++ A C PG
Sbjct: 1 MPRPGTSGRRPLLLVLLLPLFAAATSAASPSPSPSQVVEVPGVPSRPASVAVCRCCPGQT 60
Query: 53 CQATESGGYTCG--PMEPRGCA-TQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDI 109
+ + C +P+ CA Q C + VP P P+ + +Q P +
Sbjct: 61 SRRSRCIRAFCRVRSCQPKKCAGPQRCLNPVPAVPS-PSPSVRKRQVSLNWQ-PLTLQEA 118
Query: 110 DECASRPCHHGATCRNLADRYECH-CPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSF 168
R G R L R P G A V C + C +GG C V
Sbjct: 119 RALLKRRRPRGPGGRGLLRRRPPQRAPAGKAPVLCPLI--------CHNGGVC---VKPD 167
Query: 169 RCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDL----VNGFRCDCAGTGYEGTHCEREV 224
RC+C P + G CQL + A G + + R D E V
Sbjct: 168 RCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDD-----------EHGV 216
Query: 225 LECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPAL 284
S EH + + P + V E A+ +
Sbjct: 217 ASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPR 276
Query: 285 YGGVQAAFPGAFSFRHAAGFLCHCP-PGF-------EGADCGVEVDEC-ASRPCLNGGHC 335
G A + FR G C P PG GA V +C L
Sbjct: 277 EDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSER 336
Query: 336 QDLPNGFQCHCPDGY--AGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPE 386
P+G CP G+ +C EDVDEC + G C++T GY C CP+
Sbjct: 337 VSAPDG---PCPTGFERVNGSC-EDVDECATGGRCQHGECANTRGGYTCVCPD 385
Score = 53.9 bits (128), Expect = 1e-06
Identities = 50/169 (29%), Positives = 63/169 (37%), Gaps = 23/169 (13%)
Query: 1045 PGTPAPILGCRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWE----GPRCEAHVDPC 1098
PG P C+ CA P PC + G C + +F C C G++ G CE VD C
Sbjct: 746 PGAP-----CQDVDECARSPPPCTY-GRCENTEGSFQCVCPMGFQPNTAGSECE-DVDEC 798
Query: 1099 HSAPCARGRCHTHPDGRFECR-CPPGFGGPRCRLPVPSKECSLNV-TCLDGSPCEGGSPA 1156
+ G+ + G F+CR CP G R R ECS C C +
Sbjct: 799 ENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGS 857
Query: 1157 ANCSCLEGLAGQRCQVPTLPCEANPCLNG------GTCRAAGGVSECIC 1199
CSC G + P + N CL G G C G C C
Sbjct: 858 FRCSCAPGYRAPSGR-PGPCADVNECLEGDFCFPHGECLNTDGSFACTC 905
Score = 52.4 bits (124), Expect = 3e-06
Identities = 50/167 (29%), Positives = 62/167 (37%), Gaps = 33/167 (19%)
Query: 1056 GAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSA-PCARGR-CHTH-- 1111
GAP C P G C + +F C+C PG+ P PC C G C H
Sbjct: 841 GAPPCGPH-----GHCTNTEGSFRCSCAPGYRAP--SGRPGPCADVNECLEGDFCFPHGE 893
Query: 1112 ---PDGRFECRCPPGF-GGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEG-LA 1166
DG F C C PG+ GPR + ECS C G C + C C G A
Sbjct: 894 CLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGI-CTNTDGSFECICPPGHRA 952
Query: 1167 GQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKG 1213
G + CL+ CR G +C + Q CE + G
Sbjct: 953 GP---------DLASCLDVDECRERG---PALCGS----QRCENSPG 983
Score = 45.8 bits (107), Expect = 3e-04
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 9/85 (10%)
Query: 103 PRCELDIDECASRPCHHGATCRNLADRYECHCPLGY----AGVTCEMEVDEC----ASAP 154
P EL+ +EC C + + + C C GY + C ++++EC A++P
Sbjct: 1528 PYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASP 1586
Query: 155 CLHGGSCLDGVGSFRCVCAPGYGGT 179
CL+ GSFRC+C PG+ T
Sbjct: 1587 LCVNARCLNTDGSFRCICRPGFAPT 1611
Score = 45.4 bits (106), Expect = 3e-04
Identities = 26/82 (31%), Positives = 30/82 (36%), Gaps = 3/82 (3%)
Query: 803 AGCVSEDMCSPDPCFNG-GTCLVTWNDFHCTCPANFTGPTCAQQL--WCPGQPCLPPATC 859
A C D C+ P G G C F C CPA F G C + + P P C
Sbjct: 667 ASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRC 726
Query: 860 EEVPDGFVCVAEATFREGPPAA 881
+ F C A FR P A
Sbjct: 727 DNTAGSFHCACPAGFRSRGPGA 748
Score = 43.5 bits (101), Expect = 0.001
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 14/83 (16%)
Query: 182 QLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLEC----------ASAP 231
+L+ +EC G C + GF C C ++G + + C A++P
Sbjct: 1531 ELEAEECGILDGCTNGRCVRVPEGFTCRC----FDGYRLDMTRMACVDINECDEAEAASP 1586
Query: 232 CEHNASCLEGLGSFRCLCWPGYS 254
NA CL GSFRC+C PG++
Sbjct: 1587 LCVNARCLNTDGSFRCICRPGFA 1609
Score = 42.7 bits (99), Expect = 0.002
Identities = 26/85 (30%), Positives = 30/85 (35%), Gaps = 8/85 (9%)
Query: 805 CVSEDMCSPD--PCFNGGTCLVTWNDFHCTCPANFTGPT-----CAQQLWC-PGQPCLPP 856
C D CS PC G C T F C+C + P+ CA C G C P
Sbjct: 832 CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPH 891
Query: 857 ATCEEVPDGFVCVAEATFREGPPAA 881
C F C +R GP A
Sbjct: 892 GECLNTDGSFACTCAPGYRPGPRGA 916
Score = 40.0 bits (92), Expect = 0.014
Identities = 45/147 (30%), Positives = 52/147 (35%), Gaps = 35/147 (23%)
Query: 763 FRGCLQDLRLDGCHL---PFFPLPLDNSSQPSELG---GRQSWNLTAGCVSEDMC--SPD 814
FRG + +D C P P DN++ G +S A C D C SP
Sbjct: 702 FRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPP 761
Query: 815 PCFNGGTCLVTWNDFHCTCPANFTGPT----------CAQQLWCPGQPCLPPATCEEVPD 864
PC G C T F C CP F T C L CPGQ C+ P
Sbjct: 762 PC-TYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECV------NSPG 814
Query: 865 GFVCVAEATFREGPPAAFSGHNASSGR 891
F C R P SGH+ GR
Sbjct: 815 SFQC------RTCP----SGHHLHRGR 831
Score = 39.3 bits (90), Expect = 0.025
Identities = 27/84 (32%), Positives = 34/84 (40%), Gaps = 8/84 (9%)
Query: 805 CVSEDMCS--PDPCFNGGTCLVTWNDFHCTCPANF-TGPTCAQQLWCPGQPCLPP----A 857
C+ D C P PC G C + F C C F GP A+ L +PP
Sbjct: 585 CIDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLG 643
Query: 858 TCEEVPDGFVCVAEATFREGPPAA 881
CE P F+CV A ++ P A
Sbjct: 644 RCENTPGSFLCVCPAGYQAAPHGA 667
Score = 38.9 bits (89), Expect = 0.032
Identities = 28/82 (34%), Positives = 33/82 (40%), Gaps = 8/82 (9%)
Query: 807 SEDMCSPDPCFNG-GTCLVTWNDFHCTCPANFT----GPTCAQQLWCPG--QPCLPPATC 859
S MC +P G G C+ + + C C + F G C C PC P C
Sbjct: 545 SSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAP-GRC 603
Query: 860 EEVPDGFVCVAEATFREGPPAA 881
E P F CV FR GP AA
Sbjct: 604 ENSPGSFRCVCGPGFRAGPRAA 625
Score = 38.9 bits (89), Expect = 0.032
Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 7/80 (8%)
Query: 1048 PAPILGCRGAPVCAP-SPCLHDGACRDLFDAFACACGPGWEGPRCEAH---VDPCHS--A 1101
P P GC+ C S C C++L +F C C G+EG R H V+ C +
Sbjct: 1041 PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1100
Query: 1102 PCARGRCHTHPDGRFECRCP 1121
C C + +G F C CP
Sbjct: 1101 VCGAALCE-NVEGSFLCVCP 1119
Score = 38.1 bits (87), Expect = 0.055
Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 9/74 (12%)
Query: 319 VEVDECASRPCLNGGHCQDLPNGFQCHCPDGY----AGPTCEEDVDEC----LSDPCLHG 370
+E +EC G C +P GF C C DGY C D++EC + P
Sbjct: 1532 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVN 1590
Query: 371 GTCSDTVAGYICRC 384
C +T + C C
Sbjct: 1591 ARCLNTDGSFRCIC 1604
Score = 37.4 bits (85), Expect = 0.093
Identities = 23/82 (28%), Positives = 28/82 (34%), Gaps = 5/82 (6%)
Query: 805 CVSEDMC-SPDPCFNGGTCLVTWNDFHCTCPANFT----GPTCAQQLWCPGQPCLPPATC 859
C + C D CF G CL T F CTC + G +C C + C
Sbjct: 876 CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGIC 935
Query: 860 EEVPDGFVCVAEATFREGPPAA 881
F C+ R GP A
Sbjct: 936 TNTDGSFECICPPGHRAGPDLA 957
Score = 35.0 bits (79), Expect = 0.46
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 25/121 (20%)
Query: 1071 CRDLFDAFAC--ACGPGWE---GPRCEAHVDPCHSAPC--ARGRCHTHPDGRFECRCPPG 1123
C + ++ C AC PG++ G C+ VD C + A C P G F+C C G
Sbjct: 1022 CENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLP-GSFQCLCDQG 1079
Query: 1124 FGGPRCRLPVPSKECSLNVTCLDGSPCE---GGSPAANCSCLEGLAGQRCQVPTLPCEAN 1180
+ G R C+D + CE G AA C +EG C P P E +
Sbjct: 1080 YEGARD-----------GRHCVDVNECETLQGVCGAALCENVEG--SFLCVCPNSPEEFD 1126
Query: 1181 P 1181
P
Sbjct: 1127 P 1127
Score = 34.3 bits (77), Expect = 0.79
Identities = 24/84 (28%), Positives = 30/84 (35%), Gaps = 8/84 (9%)
Query: 803 AGCVSEDMCSPDPCFNGGTCLVTWNDFHCTC-PANFTGPTCAQQLWCP-----GQPCLPP 856
A C+ D CS + G C T F C C P + GP A L G
Sbjct: 916 ASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS 975
Query: 857 ATCEEVPDGFVCVAEAT--FREGP 878
CE P + CV + + GP
Sbjct: 976 QRCENSPGSYRCVRDCDPGYHAGP 999
Score = 33.1 bits (74), Expect = 1.8
Identities = 12/30 (40%), Positives = 17/30 (56%), Gaps = 1/30 (3%)
Query: 805 CVSEDMCSPD-PCFNGGTCLVTWNDFHCTC 833
C+ D C+ + P GG C+ T +HCTC
Sbjct: 1294 CIDNDECADEEPACEGGRCVNTVGSYHCTC 1323
Score = 32.0 bits (71), Expect = 3.9
Identities = 19/65 (29%), Positives = 26/65 (40%), Gaps = 9/65 (13%)
Query: 1068 DGACRDLFDAFACACGPGWEGPRCE---AHVDPCHSAP-----CARGRCHTHPDGRFECR 1119
+G C + + F C C G+ ++ C A C RC + DG F C
Sbjct: 1545 NGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARC-LNTDGSFRCI 1603
Query: 1120 CPPGF 1124
C PGF
Sbjct: 1604 CRPGF 1608
Score = 31.2 bits (69), Expect = 6.7
Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Query: 603 CERREQCRPLPCVHG-GSCVDLWTHFRCDCARPHRGPTCADEI 644
C+ ++C P + G G+C +L FRC C RG C +++
Sbjct: 669 CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDV 711
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 172 bits (436), Expect = 2e-42
Identities = 84/259 (32%), Positives = 123/259 (47%), Gaps = 37/259 (14%)
Query: 71 CATQPCHHGALCVPQGPDPTG-FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADR 129
C + PC + C DP +RC C G++G CE+ +D C+S PC +G TC
Sbjct: 929 CLSSPCQNQGTC---HNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGE 985
Query: 130 ---YECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLD 186
+ C CP G+ G TC + D+C C +GG C+DGVG++ C C Y G C+ +D
Sbjct: 986 DAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVD 1045
Query: 187 ECQSQ--PCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGS 244
C PC H C +G RC+C GY G +C +C C++ A C++ + S
Sbjct: 1046 LCSPDLNPCQHEAQCVGTPDGPRCECM-PGYAGDNCSENQDDCRDHRCQNGAQCMDEVNS 1104
Query: 245 FRCLCWPGYSGELCEV------DEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSF 298
+ CLC GYSG+LCE+ + C + CQ+G C+ + +
Sbjct: 1105 YSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRP--------------- 1149
Query: 299 RHAAGFLCHCPPGFEGADC 317
+C C PGF G +C
Sbjct: 1150 ------VCQCLPGFGGPEC 1162
Score = 159 bits (401), Expect = 2e-38
Identities = 134/483 (27%), Positives = 182/483 (37%), Gaps = 102/483 (21%)
Query: 227 CASAPCEHNASCL-EGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALY 285
C S+PC++ +C + L +RC C GY G CEV D C+S PC++GG C +
Sbjct: 929 CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEG---- 984
Query: 286 GGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCH 345
A F C CP GFEG CGV D+C C NGG C D + C
Sbjct: 985 --------------EDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQ 1030
Query: 346 CPDGYAGPTCEEDVDECLSD--PCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGH 403
CP Y G CE+ VD C D PC H C T G C C + G +CS C+ H
Sbjct: 1031 CPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDH 1090
Query: 404 TCPLAATCIPIFESGVHSYVCHCPPGTHGPFCG-----------------QNTTFSVMAG 446
C A C+ V+SY C C G G C QN V G
Sbjct: 1091 RCQNGAQCM----DEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQG 1146
Query: 447 S-PIQASVPA-GGP---------------------------LGLALRFRTTLPAGTLATR 477
+ P+ +P GGP + L+ T G L
Sbjct: 1147 NRPVCQCLPGFGGPECEKLLSVNFVDRDTYLQFTDLQNWPRANITLQVSTAEDNGILLYN 1206
Query: 478 NDTKE-SLELALVAATLQATLWSYSTTVLVLRLPDLALNDGHWHQVEVVLHLATLELRLW 536
D ++EL + SY ++ + +NDG +H VE+V + L +
Sbjct: 1207 GDNDHIAVELYQGHVRVSYDPGSYPSSAI---YSAETINDGQFHTVELVAFDQMVNLSI- 1262
Query: 537 HEGCPARLCVASGPVALASTAS--ATPLPAGISSAQ------LGDATFAGCLQDVRVDGH 588
G P + L S A +P ++SA L F GC++++ ++
Sbjct: 1263 DGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNE 1322
Query: 589 L--LLPEDLGENVLLGCERREQCRPLPCVHG-----------GSCVDLWTHFRCDCARPH 635
L + V+ GC E CR L C+HG C W CD +P
Sbjct: 1323 LQDFTKTQMKPGVVPGC---EPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCD--QPA 1377
Query: 636 RGP 638
GP
Sbjct: 1378 DGP 1380
Score = 153 bits (386), Expect = 1e-36
Identities = 86/262 (32%), Positives = 111/262 (42%), Gaps = 23/262 (8%)
Query: 20 LLLWAPALSLLAGTVPSEPPSA----CASDPCAPGTECQATESGGYTCG-PMEPRG---- 70
LLL PA P+ A C S PC C Y C P +G
Sbjct: 903 LLLTTPAKKFECQGPPTLAVQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCE 962
Query: 71 -----CATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRN 125
C++ PC +G C Q + F C C GF+GP C ++ D+C C +G C +
Sbjct: 963 VSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVD 1022
Query: 126 LADRYECHCPLGYAGVTCEMEVDECAS--APCLHGGSCLDGVGSFRCVCAPGYGGTRCQL 183
Y C CPL Y G CE VD C+ PC H C+ RC C PGY G C
Sbjct: 1023 GVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSE 1082
Query: 184 DLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCE------REVLECASAPCEHNAS 237
+ D+C+ C +G C D VN + C CA GY G CE C C++ A+
Sbjct: 1083 NQDDCRDHRCQNGAQCMDEVNSYSCLCA-EGYSGQLCEIPPHLPAPKSPCEGTECQNGAN 1141
Query: 238 CLEGLGSFRCLCWPGYSGELCE 259
C++ C C PG+ G CE
Sbjct: 1142 CVDQGNRPVCQCLPGFGGPECE 1163
Score = 109 bits (272), Expect = 2e-23
Identities = 66/221 (29%), Positives = 84/221 (38%), Gaps = 50/221 (22%)
Query: 1047 TPAPILGCRGAP---------VCAPSPCLHDGACR-DLFDAFACACGPGWEGPRCEAHVD 1096
TPA C+G P +C SPC + G C D + + CAC G++G CE +D
Sbjct: 907 TPAKKFECQGPPTLAVQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLD 966
Query: 1097 PCHSAPCARG-RCHTHP--DGRFECRCPPGFGGPRCRLPVPS---KECSLNVTCLDG--- 1147
C S PC G CH D F C CP GF GP C + C+ C+DG
Sbjct: 967 SCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGN 1026
Query: 1148 -------------------------SPCE------GGSPAANCSCLEGLAGQRCQVPTLP 1176
+PC+ G C C+ G AG C
Sbjct: 1027 YTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDD 1086
Query: 1177 CEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGLPLP 1217
C + C NG C C+C +SGQ CE+ LP P
Sbjct: 1087 CRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAP 1127
Score = 87.8 bits (216), Expect = 6e-17
Identities = 51/159 (32%), Positives = 67/159 (42%), Gaps = 13/159 (8%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSA--PCAR-GRCHTHPDGRF 1116
C C + G C D + C C +EG CE VD C PC +C PDG
Sbjct: 1009 CVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGP- 1067
Query: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPT-- 1174
C C PG+ G C +++ + C +G+ C + +C C EG +GQ C++P
Sbjct: 1068 RCECMPGYAGDNCS---ENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHL 1124
Query: 1175 ----LPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
PCE C NG C G C C F G CE
Sbjct: 1125 PAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 74.3 bits (181), Expect = 7e-13
Identities = 112/497 (22%), Positives = 163/497 (32%), Gaps = 115/497 (23%)
Query: 807 SEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC-------AQQLWCPGQPCLPPATC 859
++D C C NG C+ N + C C ++G C A + C G C A C
Sbjct: 1083 NQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANC 1142
Query: 860 EEVPDGFVCVAEATFREGPPAAFSGHNASSGRLLGGLSLAFRTRDS-------EAW---- 908
+ + VC F GP LS+ F RD+ + W
Sbjct: 1143 VDQGNRPVCQCLPGF-GGPECEKL------------LSVNFVDRDTYLQFTDLQNWPRAN 1189
Query: 909 -LLRAAAGALEGVWL-AVRNGSLAGGVRGGH--------GLPGAVLPIPGPRVADGAWHR 958
L+ + G+ L N +A + GH P + + + DG +H
Sbjct: 1190 ITLQVSTAEDNGILLYNGDNDHIAVELYQGHVRVSYDPGSYPSSAI-YSAETINDGQFHT 1248
Query: 959 VRLAMERPAATTSRWLLWLDGAA----------------TPVALRGLASDLGFLQGPGAV 1002
V L A L +DG + P+ + G+ D+ A
Sbjct: 1249 VEL-----VAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDV----NSAAF 1299
Query: 1003 R---ILLAENFTGCLGRVALGG--LPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGA 1057
R IL F GC+ + + + +PG PG
Sbjct: 1300 RLWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVPGCEP------------------ 1341
Query: 1058 PVCAPSPCLHDGACR-DLFDAFACACGPGWEGPRCEAHVD-PCHSAPCARGRCHTHPDGR 1115
C CLH G C+ + C C GW G C+ D PCH C G+C
Sbjct: 1342 --CRKLYCLH-GICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALS 1398
Query: 1116 FECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTL 1175
+ C+C G+ G C E + CL G G+ A+C C G +G+ C+ +
Sbjct: 1399 YSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQES- 1457
Query: 1176 PCEANPCLN-------GGTCRAAGGVSECICNARFSGQFCEVAKGLPL---PLPFPLL-- 1223
C +P + C+ +S C GQ C +GL L F
Sbjct: 1458 ECRGDPVRDFHQVQRGYAICQTTRPLSWVECRGSCPGQGC--CQGLRLKRRKFTFECSDG 1515
Query: 1224 -----EVAVPAACACLL 1235
EV P C C L
Sbjct: 1516 TSFAEEVEKPTKCGCAL 1532
Score = 70.5 bits (171), Expect = 1e-11
Identities = 54/202 (26%), Positives = 69/202 (34%), Gaps = 54/202 (26%)
Query: 103 PRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVD-ECASAPCLHGGSC 161
P CE C C HG N CHC G+ G+ C+ D C C+HG
Sbjct: 1337 PGCE----PCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCV 1392
Query: 162 LDGVGSFRCVCAPGYGGTRCQLD---LDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGT 218
S+ C C GY G C + C+ C HG C +G +G
Sbjct: 1393 PLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHG------------HCQASGTKGA 1440
Query: 219 HCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSP------CQH 272
HC +C PG+SGELCE E EC P Q
Sbjct: 1441 HC---------------------------VCDPGFSGELCE-QESECRGDPVRDFHQVQR 1472
Query: 273 GGRCLQRSDPALYGGVQAAFPG 294
G Q + P + + + PG
Sbjct: 1473 GYAICQTTRPLSWVECRGSCPG 1494
Score = 57.0 bits (136), Expect = 1e-07
Identities = 40/111 (36%), Positives = 48/111 (43%), Gaps = 22/111 (19%)
Query: 1110 THPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAAN-------CSCL 1162
T P +FEC+ PP L V +K C L CL SPC+ N C+C
Sbjct: 906 TTPAKKFECQGPP-------TLAVQAK-CDL---CLS-SPCQNQGTCHNDPLEVYRCACP 953
Query: 1163 EGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVS---ECICNARFSGQFCEV 1210
G G+ C+V C + PC NGGTC A G C C F G C V
Sbjct: 954 SGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGV 1004
Score = 56.2 bits (134), Expect = 2e-07
Identities = 38/133 (28%), Positives = 52/133 (39%), Gaps = 11/133 (8%)
Query: 322 DECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVD-ECLSDPCLHGGTCSDTVAGY 380
+ C CL+G + G CHC G+ G C++ D C C+HG Y
Sbjct: 1340 EPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSY 1399
Query: 381 ICRCPETWGGRDCS---VQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437
C+C + + G C+ C+G C L C G H C C PG G C Q
Sbjct: 1400 SCQCQDGYSGALCNQAGALAEPCRGLQC-LHGHCQASGTKGAH---CVCDPGFSGELCEQ 1455
Query: 438 NTTFSVMAGSPIQ 450
S G P++
Sbjct: 1456 E---SECRGDPVR 1465
Score = 56.2 bits (134), Expect = 2e-07
Identities = 44/146 (30%), Positives = 58/146 (39%), Gaps = 31/146 (21%)
Query: 225 LECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPAL 284
L C C+ NA+ C C G+ G C D+ A PC HG +C+ L
Sbjct: 1345 LYCLHGICQPNAT-----PGPMCHCEAGWVGLHC----DQPADGPC-HGHKCVHGQCVPL 1394
Query: 285 YGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADC---GVEVDECASRPCLNGGHCQDL-PN 340
A + C C G+ GA C G + C CL+G HCQ
Sbjct: 1395 ---------------DALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHG-HCQASGTK 1438
Query: 341 GFQCHCPDGYAGPTCEEDVDECLSDP 366
G C C G++G CE++ EC DP
Sbjct: 1439 GAHCVCDPGFSGELCEQE-SECRGDP 1463
Score = 48.9 bits (115), Expect = 3e-05
Identities = 31/92 (33%), Positives = 37/92 (40%), Gaps = 10/92 (10%)
Query: 781 PLPLDNSSQPSELGGRQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWND---FHCTCPANF 837
PL + + PS GR VS D CS PC NGGTC + F C+CP F
Sbjct: 944 PLEVYRCACPSGYKGRDCE------VSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGF 997
Query: 838 TGPTCAQQL-WCPGQPCLPPATCEEVPDGFVC 868
GPTC C C C + + C
Sbjct: 998 EGPTCGVNTDDCVDHACANGGVCVDGVGNYTC 1029
Score = 45.1 bits (105), Expect = 4e-04
Identities = 24/66 (36%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQ--QLWCPG-QPCLPPATCEEV 862
V+ D C C NGG C+ ++ C CP + G C Q L P PC A C
Sbjct: 1004 VNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGT 1063
Query: 863 PDGFVC 868
PDG C
Sbjct: 1064 PDGPRC 1069
Score = 43.5 bits (101), Expect = 0.001
Identities = 70/304 (23%), Positives = 113/304 (37%), Gaps = 60/304 (19%)
Query: 606 REQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIPAATFGLGGAPSSASFL---- 661
+ C C +G +CVD C C GP C +++ + F ++L
Sbjct: 1128 KSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPEC-EKLLSVNF-----VDRDTYLQFTD 1181
Query: 662 LQELPGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEV-PG---SPAVVL 717
LQ P N+T+ + T E G+LL N + V L +G +R PG S A+
Sbjct: 1182 LQNWPRANITLQ--VSTAEDNGILLY--NGDNDHIAVELYQGHVRVSYDPGSYPSSAIYS 1237
Query: 718 PGRWDDGLRHLVML------------SFGPDQLQDLGQH--------VHVGGRLLAADSQ 757
+DG H V L P + + G+H ++VGG + +S
Sbjct: 1238 AETINDGQFHTVELVAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSA 1297
Query: 758 PW-------GGPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELGGRQSWNLTAGCVSEDM 810
+ G F GC+++L ++ F + P R+ + L C +
Sbjct: 1298 AFRLWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVPGCEPCRKLYCLHGIC--QPN 1355
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLP------PATCEEVPD 864
+P P + C W HC PA+ GP + C C+P C++
Sbjct: 1356 ATPGPMCH---CEAGWVGLHCDQPAD--GPCHGHK--CVHGQCVPLDALSYSCQCQDGYS 1408
Query: 865 GFVC 868
G +C
Sbjct: 1409 GALC 1412
Score = 42.4 bits (98), Expect = 0.003
Identities = 35/107 (32%), Positives = 44/107 (41%), Gaps = 19/107 (17%)
Query: 782 LPLDNSSQPSELGGRQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWND----FHCTCPANF 837
L L ++ E G + + A C D+C PC N GTC ND + C CP+ +
Sbjct: 903 LLLTTPAKKFECQGPPTLAVQAKC---DLCLSSPCQNQGTC---HNDPLEVYRCACPSGY 956
Query: 838 TGPTCAQQL-WCPGQPCLPPATC-----EEVPDGFVCVAEATFREGP 878
G C L C PC TC E+ P F C F EGP
Sbjct: 957 KGRDCEVSLDSCSSGPCENGGTCHAQEGEDAP--FTCSCPTGF-EGP 1000
Score = 36.2 bits (82), Expect = 0.21
Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 809 DMCSPD--PCFNGGTCLVTWNDFHCTCPANFTGPTCAQ-QLWCPGQPCLPPATCEEVPDG 865
D+CSPD PC + C+ T + C C + G C++ Q C C A C + +
Sbjct: 1045 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNS 1104
Query: 866 FVCV 869
+ C+
Sbjct: 1105 YSCL 1108
Score = 35.8 bits (81), Expect = 0.27
Identities = 25/82 (30%), Positives = 30/82 (36%), Gaps = 11/82 (13%)
Query: 42 CASDPCAP----GTECQATESGGYTCGPMEPRGCATQPCHHGALCVP---QGPDPTGFRC 94
C C P CQ + GY+ G +PC G C+ Q G C
Sbjct: 1386 CVHGQCVPLDALSYSCQCQD--GYSGALCNQAGALAEPCR-GLQCLHGHCQASGTKGAHC 1442
Query: 95 YCVPGFQGPRCELDIDECASRP 116
C PGF G CE + EC P
Sbjct: 1443 VCDPGFSGELCEQE-SECRGDP 1463
Score = 31.6 bits (70), Expect = 5.1
Identities = 16/50 (32%), Positives = 21/50 (42%), Gaps = 1/50 (2%)
Query: 803 AGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQP 852
AG ++E C C +G HC C F+G C Q+ C G P
Sbjct: 1415 AGALAEP-CRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESECRGDP 1463
>gi|8393264 delta-like 3 protein isoform 1 precursor [Homo sapiens]
Length = 618
Score = 170 bits (430), Expect = 9e-42
Identities = 80/196 (40%), Positives = 105/196 (53%), Gaps = 18/196 (9%)
Query: 39 PSACASDPCAPGTECQAT-ESGGYTCGPMEPRG------------CATQPCHHGALCVPQ 85
P C +PCA G C T S TC PRG CA PC +G LCV
Sbjct: 275 PGPCDGNPCANGGSCSETPRSFECTC----PRGFYGLRCEVSGVTCADGPCFNGGLCVGG 330
Query: 86 GPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEM 145
+ + C+C PGFQG CE +D C+ +PC +G C +L C C G+AG CE
Sbjct: 331 ADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEH 390
Query: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNG 205
++D+CA C +GG+C++G G+ RC CA G+GG C+ D C ++PCAHGG C+ +G
Sbjct: 391 DLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSG 450
Query: 206 FRCDCAGTGYEGTHCE 221
C CA GY G CE
Sbjct: 451 LVCACA-PGYMGARCE 465
Score = 166 bits (421), Expect = 1e-40
Identities = 102/320 (31%), Positives = 131/320 (40%), Gaps = 43/320 (13%)
Query: 120 GATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFR----CVCAPG 175
G C L G C DEC AP + C G C C G
Sbjct: 184 GTACTRLCRPRSAPSRCGPGLRPCAPLEDEC-EAPLVCRAGCSPEHGFCEQPGECRCLEG 242
Query: 176 YGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHN 235
+ G C + + + C G C G G C PC +
Sbjct: 243 WTGPLCTVPVS---TSSCLSPRGPSSATTG--CLVPGPG-----------PCDGNPCANG 286
Query: 236 ASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGA 295
SC E SF C C G+ G CEV CA PC +GG C+ +DP
Sbjct: 287 GSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPD------------ 334
Query: 296 FSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTC 355
+ ++CHCPPGF+G++C VD C+ +PC NGG C DL + +C C G+AGP C
Sbjct: 335 ------SAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRC 388
Query: 356 EEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIF 415
E D+D+C C +GGTC + + C C +GGRDC + C C C F
Sbjct: 389 EHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHF 448
Query: 416 ESGVHSYVCHCPPGTHGPFC 435
SG+ VC C PG G C
Sbjct: 449 -SGL---VCACAPGYMGARC 464
Score = 162 bits (410), Expect = 2e-39
Identities = 104/341 (30%), Positives = 140/341 (41%), Gaps = 50/341 (14%)
Query: 23 WAPALSLLAGTVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALC 82
W S A P +AC C P + G C P+E A C G C
Sbjct: 168 WELRFSYRARCEPPAVGTACTR-LCRPRSAPSRCGPGLRPCAPLEDECEAPLVCRAG--C 224
Query: 83 VPQ-GPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGV 141
P+ G C C+ G+ GP C + + + C P G +
Sbjct: 225 SPEHGFCEQPGECRCLEGWTGPLCTVPVSTSS------------------CLSPRGPSSA 266
Query: 142 TCEMEVD---ECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGT 198
T V C PC +GGSC + SF C C G+ G RC++ C PC +GG
Sbjct: 267 TTGCLVPGPGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGL 326
Query: 199 C---HDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSG 255
C D + + C C G++G++CE+ V C+ PC + CL+ + RC C G++G
Sbjct: 327 CVGGADPDSAYICHCP-PGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAG 385
Query: 256 ELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGA 315
CE D D+CA C +GG C++ GG C C GF G
Sbjct: 386 PRCEHDLDDCAGRACANGGTCVEG------GGAHR---------------CSCALGFGGR 424
Query: 316 DCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE 356
DC D CA+RPC +GG C +G C C GY G CE
Sbjct: 425 DCRERADPCAARPCAHGGRCYAHFSGLVCACAPGYMGARCE 465
Score = 110 bits (275), Expect = 9e-24
Identities = 81/259 (31%), Positives = 99/259 (38%), Gaps = 32/259 (12%)
Query: 978 DGAATPVALR-GLASDLGFLQGPGAVRILLAENFTG-----------CLGRVALGGLPLP 1025
D P+ R G + + GF + PG R L E +TG CL
Sbjct: 212 DECEAPLVCRAGCSPEHGFCEQPGECRCL--EGWTGPLCTVPVSTSSCLSPRGPSSATTG 269
Query: 1026 LARPRPGAAPG--------AREHFASWPGT-PAPILGCR---GAPVCAPSPCLHDGAC-- 1071
P PG G E S+ T P G R CA PC + G C
Sbjct: 270 CLVPGPGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVG 329
Query: 1072 -RDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCR 1130
D A+ C C PG++G CE VD C PC G CRC GF GPRC
Sbjct: 330 GADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCE 389
Query: 1131 LPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRA 1190
+ +C+ C +G C G A CSC G G+ C+ PC A PC +GG C A
Sbjct: 390 HDL--DDCA-GRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYA 446
Query: 1191 AGGVSECICNARFSGQFCE 1209
C C + G CE
Sbjct: 447 HFSGLVCACAPGYMGARCE 465
Score = 82.4 bits (202), Expect = 3e-15
Identities = 42/117 (35%), Positives = 50/117 (42%), Gaps = 3/117 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C+ PC + G C DL A C C G+ GPRCE +D C CA G G C
Sbjct: 357 CSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCS 416
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP 1176
C GFGG CR + C+ C G C C+C G G RC+ P P
Sbjct: 417 CALGFGGRDCR--ERADPCAAR-PCAHGGRCYAHFSGLVCACAPGYMGARCEFPVHP 470
Score = 65.9 bits (159), Expect = 2e-10
Identities = 45/133 (33%), Positives = 54/133 (40%), Gaps = 23/133 (17%)
Query: 1082 CGPGWEGPRCEAHVDPCHSAPCARGRC---HTHPDGRFECRCPPGFGGPRCRLPVPSKEC 1138
CGPG C D C + R C H + ECRC G+ GP C +PV + C
Sbjct: 200 CGPGLRP--CAPLEDECEAPLVCRAGCSPEHGFCEQPGECRCLEGWTGPLCTVPVSTSSC 257
Query: 1139 SLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECI 1198
SP G +A CL G PC+ NPC NGG+C EC
Sbjct: 258 L--------SP--RGPSSATTGCLVPGPG--------PCDGNPCANGGSCSETPRSFECT 299
Query: 1199 CNARFSGQFCEVA 1211
C F G CEV+
Sbjct: 300 CPRGFYGLRCEVS 312
Score = 65.1 bits (157), Expect = 4e-10
Identities = 47/156 (30%), Positives = 54/156 (34%), Gaps = 53/156 (33%)
Query: 42 CASDPCAPGTECQ--ATESGGYTCG-PMEPRG---------CATQPCHHGALCVPQGPDP 89
CA PC G C A Y C P +G C+ QPC +G LC+ G
Sbjct: 316 CADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGH-- 373
Query: 90 TGFRCYCVPGFQGPRCELDIDECA------------------------------------ 113
RC C GF GPRCE D+D+CA
Sbjct: 374 -ALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADP 432
Query: 114 --SRPCHHGATCRNLADRYECHCPLGYAGVTCEMEV 147
+RPC HG C C C GY G CE V
Sbjct: 433 CAARPCAHGGRCYAHFSGLVCACAPGYMGARCEFPV 468
Score = 51.2 bits (121), Expect = 6e-06
Identities = 31/91 (34%), Positives = 39/91 (42%), Gaps = 6/91 (6%)
Query: 772 LDGCHLPFFPLPLDNSSQPSELGGRQSWNLTAGCV--SEDMCSPDPCFNGGTCLVTWNDF 829
L+G P +P+ SS S G + T GC+ C +PC NGG+C T F
Sbjct: 240 LEGWTGPLCTVPVSTSSCLSPRGPSSA---TTGCLVPGPGPCDGNPCANGGSCSETPRSF 296
Query: 830 HCTCPANFTGPTC-AQQLWCPGQPCLPPATC 859
CTCP F G C + C PC C
Sbjct: 297 ECTCPRGFYGLRCEVSGVTCADGPCFNGGLC 327
Score = 50.4 bits (119), Expect = 1e-05
Identities = 24/54 (44%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEE 861
D CS PC NGG CL + C C A F GP C L C G+ C TC E
Sbjct: 355 DRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVE 408
Score = 48.1 bits (113), Expect = 5e-05
Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 2/50 (4%)
Query: 1057 APVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCE--AHVDPCHSAPCA 1104
A CA PC H G C F CAC PG+ G RCE H D + P A
Sbjct: 430 ADPCAARPCAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASALPAA 479
Score = 47.0 bits (110), Expect = 1e-04
Identities = 48/182 (26%), Positives = 62/182 (34%), Gaps = 13/182 (7%)
Query: 763 FRGCLQDLRLDGCHLPFFPLPLDNSSQPSELGGRQSWNLTAGCVSE------DMCSPDPC 816
F+G + R+D C L P N +LG AG D C+ C
Sbjct: 345 FQGSNCEKRVDRCSLQ----PCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRAC 400
Query: 817 FNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCVAEATFR 875
NGGTC+ C+C F G C ++ C +PC C G VC +
Sbjct: 401 ANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLVCACAPGYM 460
Query: 876 EGPPAAFSGHNASSGRLLGGLSLAFRTRDSEAWLLRAAAGALEGVWLAVRNGSLAGGVRG 935
G F H L R D + +LL A G L +A L R
Sbjct: 461 -GARCEFPVH-PDGASALPAAPPGLRPGDPQRYLLPPALGLLVAAGVAGAALLLVHVRRR 518
Query: 936 GH 937
GH
Sbjct: 519 GH 520
Score = 43.1 bits (100), Expect = 0.002
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 4/73 (5%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWND---FHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEE 861
VS C+ PCFNGG C+ + + C CP F G C +++ C QPC C +
Sbjct: 311 VSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLD 370
Query: 862 VPDGFVCVAEATF 874
+ C A F
Sbjct: 371 LGHALRCRCRAGF 383
Score = 39.7 bits (91), Expect = 0.019
Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 603 CERR-EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
CE+R ++C PC +GG C+DL RC C GP C ++
Sbjct: 350 CEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDL 392
Score = 39.3 bits (90), Expect = 0.025
Identities = 78/324 (24%), Positives = 98/324 (30%), Gaps = 62/324 (19%)
Query: 634 PHRGPTCADEIPAATFGLG---GAPSSASFLLQELPGPNLTVSFLLRTRESAGLLLQFAN 690
P P E+ +FG G GAP S L R GL + A
Sbjct: 22 PQTRPAGVFELQIHSFGPGPGPGAPRSPC-------SARLPCRLFFRVCLKPGLSEEAAE 74
Query: 691 DSAAGLTVFLSEGRIRAEVPGSPAVVLPGRWDDGLRHLVMLSFGPDQL--------QDLG 742
A + G + E PG+PA LP DGL + P ++LG
Sbjct: 75 SPCALGAALSARGPVYTEQPGAPAPDLP--LPDGLLQVPFRDAWPGTFSFIIETWREELG 132
Query: 743 QHV---------HVGGRLLAADSQPWGGPF-RGCLQDLRLD---GCHLPFFPLPLDNSSQ 789
+ V GR A PW R +LR C P +
Sbjct: 133 DQIGGPAWSLLARVAGRRRLAAGGPWARDIQRAGAWELRFSYRARCEPPAVGTACTRLCR 192
Query: 790 PSELGGRQSWNLTAGCVSEDMC-SPDPCFNGGT-------------CLVTWNDFHCTCPA 835
P R L ED C +P C G + CL W CT P
Sbjct: 193 PRSAPSRCGPGLRPCAPLEDECEAPLVCRAGCSPEHGFCEQPGECRCLEGWTGPLCTVPV 252
Query: 836 NFT------GPTCAQQLW-------CPGQPCLPPATCEEVPDGFVCVAEATFREGPPAAF 882
+ + GP+ A C G PC +C E P F C F G
Sbjct: 253 STSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGGSCSETPRSFECTCPRGF-YGLRCEV 311
Query: 883 SGHNASSGRLL-GGLSLAFRTRDS 905
SG + G GGL + DS
Sbjct: 312 SGVTCADGPCFNGGLCVGGADPDS 335
Score = 37.7 bits (86), Expect = 0.071
Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 8/56 (14%)
Query: 604 ERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC--------ADEIPAATFGL 651
ER + C PC HGG C ++ C CA + G C A +PAA GL
Sbjct: 428 ERADPCAARPCAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASALPAAPPGL 483
Score = 35.8 bits (81), Expect = 0.27
Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 10/68 (14%)
Query: 609 CRPLPCVHGGSCVDLWTHFRCDCARPH-------RGPTCADEIPAATFGL--GGAPSSAS 659
C PC +GGSC + F C C R G TCAD P GL GGA ++
Sbjct: 278 CDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADG-PCFNGGLCVGGADPDSA 336
Query: 660 FLLQELPG 667
++ PG
Sbjct: 337 YICHCPPG 344
>gi|45243561 delta-like 3 protein isoform 2 precursor [Homo sapiens]
Length = 587
Score = 170 bits (430), Expect = 9e-42
Identities = 80/196 (40%), Positives = 105/196 (53%), Gaps = 18/196 (9%)
Query: 39 PSACASDPCAPGTECQAT-ESGGYTCGPMEPRG------------CATQPCHHGALCVPQ 85
P C +PCA G C T S TC PRG CA PC +G LCV
Sbjct: 275 PGPCDGNPCANGGSCSETPRSFECTC----PRGFYGLRCEVSGVTCADGPCFNGGLCVGG 330
Query: 86 GPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEM 145
+ + C+C PGFQG CE +D C+ +PC +G C +L C C G+AG CE
Sbjct: 331 ADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEH 390
Query: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNG 205
++D+CA C +GG+C++G G+ RC CA G+GG C+ D C ++PCAHGG C+ +G
Sbjct: 391 DLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSG 450
Query: 206 FRCDCAGTGYEGTHCE 221
C CA GY G CE
Sbjct: 451 LVCACA-PGYMGARCE 465
Score = 166 bits (421), Expect = 1e-40
Identities = 102/320 (31%), Positives = 131/320 (40%), Gaps = 43/320 (13%)
Query: 120 GATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFR----CVCAPG 175
G C L G C DEC AP + C G C C G
Sbjct: 184 GTACTRLCRPRSAPSRCGPGLRPCAPLEDEC-EAPLVCRAGCSPEHGFCEQPGECRCLEG 242
Query: 176 YGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHN 235
+ G C + + + C G C G G C PC +
Sbjct: 243 WTGPLCTVPVS---TSSCLSPRGPSSATTG--CLVPGPG-----------PCDGNPCANG 286
Query: 236 ASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGA 295
SC E SF C C G+ G CEV CA PC +GG C+ +DP
Sbjct: 287 GSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPD------------ 334
Query: 296 FSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTC 355
+ ++CHCPPGF+G++C VD C+ +PC NGG C DL + +C C G+AGP C
Sbjct: 335 ------SAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRC 388
Query: 356 EEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIF 415
E D+D+C C +GGTC + + C C +GGRDC + C C C F
Sbjct: 389 EHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHF 448
Query: 416 ESGVHSYVCHCPPGTHGPFC 435
SG+ VC C PG G C
Sbjct: 449 -SGL---VCACAPGYMGARC 464
Score = 162 bits (410), Expect = 2e-39
Identities = 104/341 (30%), Positives = 140/341 (41%), Gaps = 50/341 (14%)
Query: 23 WAPALSLLAGTVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALC 82
W S A P +AC C P + G C P+E A C G C
Sbjct: 168 WELRFSYRARCEPPAVGTACTR-LCRPRSAPSRCGPGLRPCAPLEDECEAPLVCRAG--C 224
Query: 83 VPQ-GPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGV 141
P+ G C C+ G+ GP C + + + C P G +
Sbjct: 225 SPEHGFCEQPGECRCLEGWTGPLCTVPVSTSS------------------CLSPRGPSSA 266
Query: 142 TCEMEVD---ECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGT 198
T V C PC +GGSC + SF C C G+ G RC++ C PC +GG
Sbjct: 267 TTGCLVPGPGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGL 326
Query: 199 C---HDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSG 255
C D + + C C G++G++CE+ V C+ PC + CL+ + RC C G++G
Sbjct: 327 CVGGADPDSAYICHCP-PGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAG 385
Query: 256 ELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGA 315
CE D D+CA C +GG C++ GG C C GF G
Sbjct: 386 PRCEHDLDDCAGRACANGGTCVEG------GGAHR---------------CSCALGFGGR 424
Query: 316 DCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE 356
DC D CA+RPC +GG C +G C C GY G CE
Sbjct: 425 DCRERADPCAARPCAHGGRCYAHFSGLVCACAPGYMGARCE 465
Score = 110 bits (275), Expect = 9e-24
Identities = 81/259 (31%), Positives = 99/259 (38%), Gaps = 32/259 (12%)
Query: 978 DGAATPVALR-GLASDLGFLQGPGAVRILLAENFTG-----------CLGRVALGGLPLP 1025
D P+ R G + + GF + PG R L E +TG CL
Sbjct: 212 DECEAPLVCRAGCSPEHGFCEQPGECRCL--EGWTGPLCTVPVSTSSCLSPRGPSSATTG 269
Query: 1026 LARPRPGAAPG--------AREHFASWPGT-PAPILGCR---GAPVCAPSPCLHDGAC-- 1071
P PG G E S+ T P G R CA PC + G C
Sbjct: 270 CLVPGPGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVG 329
Query: 1072 -RDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCR 1130
D A+ C C PG++G CE VD C PC G CRC GF GPRC
Sbjct: 330 GADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCE 389
Query: 1131 LPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRA 1190
+ +C+ C +G C G A CSC G G+ C+ PC A PC +GG C A
Sbjct: 390 HDL--DDCA-GRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYA 446
Query: 1191 AGGVSECICNARFSGQFCE 1209
C C + G CE
Sbjct: 447 HFSGLVCACAPGYMGARCE 465
Score = 82.4 bits (202), Expect = 3e-15
Identities = 42/117 (35%), Positives = 50/117 (42%), Gaps = 3/117 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
C+ PC + G C DL A C C G+ GPRCE +D C CA G G C
Sbjct: 357 CSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCS 416
Query: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP 1176
C GFGG CR + C+ C G C C+C G G RC+ P P
Sbjct: 417 CALGFGGRDCR--ERADPCAAR-PCAHGGRCYAHFSGLVCACAPGYMGARCEFPVHP 470
Score = 65.9 bits (159), Expect = 2e-10
Identities = 45/133 (33%), Positives = 54/133 (40%), Gaps = 23/133 (17%)
Query: 1082 CGPGWEGPRCEAHVDPCHSAPCARGRC---HTHPDGRFECRCPPGFGGPRCRLPVPSKEC 1138
CGPG C D C + R C H + ECRC G+ GP C +PV + C
Sbjct: 200 CGPGLRP--CAPLEDECEAPLVCRAGCSPEHGFCEQPGECRCLEGWTGPLCTVPVSTSSC 257
Query: 1139 SLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECI 1198
SP G +A CL G PC+ NPC NGG+C EC
Sbjct: 258 L--------SP--RGPSSATTGCLVPGPG--------PCDGNPCANGGSCSETPRSFECT 299
Query: 1199 CNARFSGQFCEVA 1211
C F G CEV+
Sbjct: 300 CPRGFYGLRCEVS 312
Score = 65.1 bits (157), Expect = 4e-10
Identities = 47/156 (30%), Positives = 54/156 (34%), Gaps = 53/156 (33%)
Query: 42 CASDPCAPGTECQ--ATESGGYTCG-PMEPRG---------CATQPCHHGALCVPQGPDP 89
CA PC G C A Y C P +G C+ QPC +G LC+ G
Sbjct: 316 CADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGH-- 373
Query: 90 TGFRCYCVPGFQGPRCELDIDECA------------------------------------ 113
RC C GF GPRCE D+D+CA
Sbjct: 374 -ALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADP 432
Query: 114 --SRPCHHGATCRNLADRYECHCPLGYAGVTCEMEV 147
+RPC HG C C C GY G CE V
Sbjct: 433 CAARPCAHGGRCYAHFSGLVCACAPGYMGARCEFPV 468
Score = 51.2 bits (121), Expect = 6e-06
Identities = 31/91 (34%), Positives = 39/91 (42%), Gaps = 6/91 (6%)
Query: 772 LDGCHLPFFPLPLDNSSQPSELGGRQSWNLTAGCV--SEDMCSPDPCFNGGTCLVTWNDF 829
L+G P +P+ SS S G + T GC+ C +PC NGG+C T F
Sbjct: 240 LEGWTGPLCTVPVSTSSCLSPRGPSSA---TTGCLVPGPGPCDGNPCANGGSCSETPRSF 296
Query: 830 HCTCPANFTGPTC-AQQLWCPGQPCLPPATC 859
CTCP F G C + C PC C
Sbjct: 297 ECTCPRGFYGLRCEVSGVTCADGPCFNGGLC 327
Score = 50.4 bits (119), Expect = 1e-05
Identities = 24/54 (44%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEE 861
D CS PC NGG CL + C C A F GP C L C G+ C TC E
Sbjct: 355 DRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVE 408
Score = 48.1 bits (113), Expect = 5e-05
Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 2/50 (4%)
Query: 1057 APVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCE--AHVDPCHSAPCA 1104
A CA PC H G C F CAC PG+ G RCE H D + P A
Sbjct: 430 ADPCAARPCAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASALPAA 479
Score = 47.0 bits (110), Expect = 1e-04
Identities = 48/182 (26%), Positives = 62/182 (34%), Gaps = 13/182 (7%)
Query: 763 FRGCLQDLRLDGCHLPFFPLPLDNSSQPSELGGRQSWNLTAGCVSE------DMCSPDPC 816
F+G + R+D C L P N +LG AG D C+ C
Sbjct: 345 FQGSNCEKRVDRCSLQ----PCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRAC 400
Query: 817 FNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCVAEATFR 875
NGGTC+ C+C F G C ++ C +PC C G VC +
Sbjct: 401 ANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLVCACAPGYM 460
Query: 876 EGPPAAFSGHNASSGRLLGGLSLAFRTRDSEAWLLRAAAGALEGVWLAVRNGSLAGGVRG 935
G F H L R D + +LL A G L +A L R
Sbjct: 461 -GARCEFPVH-PDGASALPAAPPGLRPGDPQRYLLPPALGLLVAAGVAGAALLLVHVRRR 518
Query: 936 GH 937
GH
Sbjct: 519 GH 520
Score = 43.1 bits (100), Expect = 0.002
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 4/73 (5%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWND---FHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEE 861
VS C+ PCFNGG C+ + + C CP F G C +++ C QPC C +
Sbjct: 311 VSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLD 370
Query: 862 VPDGFVCVAEATF 874
+ C A F
Sbjct: 371 LGHALRCRCRAGF 383
Score = 39.7 bits (91), Expect = 0.019
Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 603 CERR-EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
CE+R ++C PC +GG C+DL RC C GP C ++
Sbjct: 350 CEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDL 392
Score = 39.3 bits (90), Expect = 0.025
Identities = 78/324 (24%), Positives = 98/324 (30%), Gaps = 62/324 (19%)
Query: 634 PHRGPTCADEIPAATFGLG---GAPSSASFLLQELPGPNLTVSFLLRTRESAGLLLQFAN 690
P P E+ +FG G GAP S L R GL + A
Sbjct: 22 PQTRPAGVFELQIHSFGPGPGPGAPRSPC-------SARLPCRLFFRVCLKPGLSEEAAE 74
Query: 691 DSAAGLTVFLSEGRIRAEVPGSPAVVLPGRWDDGLRHLVMLSFGPDQL--------QDLG 742
A + G + E PG+PA LP DGL + P ++LG
Sbjct: 75 SPCALGAALSARGPVYTEQPGAPAPDLP--LPDGLLQVPFRDAWPGTFSFIIETWREELG 132
Query: 743 QHV---------HVGGRLLAADSQPWGGPF-RGCLQDLRLD---GCHLPFFPLPLDNSSQ 789
+ V GR A PW R +LR C P +
Sbjct: 133 DQIGGPAWSLLARVAGRRRLAAGGPWARDIQRAGAWELRFSYRARCEPPAVGTACTRLCR 192
Query: 790 PSELGGRQSWNLTAGCVSEDMC-SPDPCFNGGT-------------CLVTWNDFHCTCPA 835
P R L ED C +P C G + CL W CT P
Sbjct: 193 PRSAPSRCGPGLRPCAPLEDECEAPLVCRAGCSPEHGFCEQPGECRCLEGWTGPLCTVPV 252
Query: 836 NFT------GPTCAQQLW-------CPGQPCLPPATCEEVPDGFVCVAEATFREGPPAAF 882
+ + GP+ A C G PC +C E P F C F G
Sbjct: 253 STSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGGSCSETPRSFECTCPRGF-YGLRCEV 311
Query: 883 SGHNASSGRLL-GGLSLAFRTRDS 905
SG + G GGL + DS
Sbjct: 312 SGVTCADGPCFNGGLCVGGADPDS 335
Score = 37.7 bits (86), Expect = 0.071
Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 8/56 (14%)
Query: 604 ERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC--------ADEIPAATFGL 651
ER + C PC HGG C ++ C CA + G C A +PAA GL
Sbjct: 428 ERADPCAARPCAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASALPAAPPGL 483
Score = 35.8 bits (81), Expect = 0.27
Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 10/68 (14%)
Query: 609 CRPLPCVHGGSCVDLWTHFRCDCARPH-------RGPTCADEIPAATFGL--GGAPSSAS 659
C PC +GGSC + F C C R G TCAD P GL GGA ++
Sbjct: 278 CDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADG-PCFNGGLCVGGADPDSA 336
Query: 660 FLLQELPG 667
++ PG
Sbjct: 337 YICHCPPG 344
>gi|45593147 EGF-like-domain, multiple 9 [Homo sapiens]
Length = 383
Score = 169 bits (427), Expect = 2e-41
Identities = 102/299 (34%), Positives = 138/299 (46%), Gaps = 43/299 (14%)
Query: 134 CPLGYAGVTCEMEVDECASAPCLHGGSCL-DGVGSFRCVCAPGYGGTRCQLDLDECQSQP 192
C LG G + D+C+S L G C DG C C PG+ G C+ C P
Sbjct: 15 CILGAPGQP--VRADDCSSHCDLAHGCCAPDG----SCRCDPGWEGLHCE----RCVRMP 64
Query: 193 CAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECAS-APCEHNASCL-EGLGSFRCLCW 250
GTCH ++C C +G+ G C+++ C + +PC++ C+ +G G + C+C
Sbjct: 65 GCQHGTCHQ---PWQCICH-SGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCL 120
Query: 251 PGYSGELCEVDEDEC--ASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHC 308
PG+ G CE C A SPC++GG+C AL F C C
Sbjct: 121 PGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFAL------------------NFTCRC 162
Query: 309 PPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCL 368
GF GA C V VD+C RPC NG C D N F C CP+G+AG C ++D+C S PC
Sbjct: 163 LVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQ 222
Query: 369 HGGTCSDTVAGYICRCPETWGGRDCSVQL------TGCQGHTCPLAATCIPIFESGVHS 421
G C D V + C CP +GG+ C + L T P +A +P HS
Sbjct: 223 RGARCRDRVHDFDCLCPSGYGGKTCELVLPVPDPPTTVDTPLGPTSAVVVPATGPAPHS 281
Score = 165 bits (417), Expect = 3e-40
Identities = 130/403 (32%), Positives = 164/403 (40%), Gaps = 84/403 (20%)
Query: 186 DECQSQ-PCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAP-CEHNASCLEGLG 243
D+C S AHG D RCD G+EG HCER C P C+H +C +
Sbjct: 27 DDCSSHCDLAHGCCAPD--GSCRCD---PGWEGLHCER----CVRMPGCQHG-TCHQ--- 73
Query: 244 SFRCLCWPGYSGELCEVDEDECAS-SPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAA 302
++C+C G++G+ C+ DE C + SPCQ+GG+C+ Y G
Sbjct: 74 PWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCM-------YDG-------------GG 113
Query: 303 GFLCHCPPGFEGADCGVEVDEC--ASRPCLNGGHCQD---LPNGFQCHCPDGYAGPTCEE 357
+ C C PGF G DC + C A PC NGG CQD F C C G+ G CE
Sbjct: 114 EYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEV 173
Query: 358 DVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFES 417
+VD+CL PC +G TC D + + C CPE + GR C++ L C C A C
Sbjct: 174 NVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARC----RD 229
Query: 418 GVHSYVCHCPPGTHGPFC-------GQNTTFSVMAGSPIQASVPAGGPLGLALRFRTTLP 470
VH + C CP G G C TT G VPA GP
Sbjct: 230 RVHDFDCLCPSGYGGKTCELVLPVPDPPTTVDTPLGPTSAVVVPATGP--------APHS 281
Query: 471 AGTLATRNDTKESLELALVAATLQATLWSYSTTVLVLRLPDLALNDGHWHQVEVVLHLAT 530
AG R KE V +A L S LV+ + + L LAT
Sbjct: 282 AGAGLLRISVKE------VVRRQEAGLGEPSLVALVV-----------FGALTAALVLAT 324
Query: 531 --LELRLWHEG-CPARLCVAS----GPVALASTASATPLPAGI 566
L LR W G CP C P + LPAG+
Sbjct: 325 VLLTLRAWRRGVCPPGPCCYPAPHYAPACQDQECQVSMLPAGL 367
Score = 157 bits (398), Expect = 5e-38
Identities = 88/248 (35%), Positives = 116/248 (46%), Gaps = 45/248 (18%)
Query: 78 HGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRP-CHHGATCRNLADRYECHCPL 136
HG C P G C C PG++G CE C P C HG TC ++C C
Sbjct: 37 HGC-CAPDGS------CRCDPGWEGLHCE----RCVRMPGCQHG-TCH---QPWQCICHS 81
Query: 137 GYAGVTCEMEVDECAS-APCLHGGSCL-DGVGSFRCVCAPGYGGTRCQLDLDECQ--SQP 192
G+AG C+ + C + +PC +GG C+ DG G + CVC PG+ G C+ C+ P
Sbjct: 82 GWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSP 141
Query: 193 CAHGGTCHD---LVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLC 249
C +GG C D F C C G+ G CE V +C PC + A+CL+G+ F CLC
Sbjct: 142 CRNGGQCQDDQGFALNFTCRCL-VGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLC 200
Query: 250 WPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCP 309
G++G C ++ D+CAS PCQ G RC R F C CP
Sbjct: 201 PEGFAGRFCTINLDDCASRPCQRGARCRDR---------------------VHDFDCLCP 239
Query: 310 PGFEGADC 317
G+ G C
Sbjct: 240 SGYGGKTC 247
Score = 138 bits (347), Expect = 4e-32
Identities = 63/157 (40%), Positives = 86/157 (54%), Gaps = 9/157 (5%)
Query: 71 CATQ-PCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDEC--ASRPCHHGATCRN-- 125
C TQ PC +G C+ G + C C+PGF G CE C A PC +G C++
Sbjct: 95 CTTQSPCQNGGQCMYDGGGE--YHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQ 152
Query: 126 -LADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLD 184
A + C C +G+ G CE+ VD+C PC +G +CLDG+ F C+C G+ G C ++
Sbjct: 153 GFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTIN 212
Query: 185 LDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCE 221
LD+C S+PC G C D V+ F C C +GY G CE
Sbjct: 213 LDDCASRPCQRGARCRDRVHDFDCLCP-SGYGGKTCE 248
Score = 127 bits (320), Expect = 5e-29
Identities = 61/155 (39%), Positives = 78/155 (50%), Gaps = 18/155 (11%)
Query: 46 PCAPGTECQATESGGYTC---------------GPMEPRGCATQPCHHGALCVPQGPDPT 90
PC G +C G Y C GP E G PC +G C
Sbjct: 100 PCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAG---SPCRNGGQCQDDQGFAL 156
Query: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC 150
F C C+ GF G RCE+++D+C RPC +GATC + +R+ C CP G+AG C + +D+C
Sbjct: 157 NFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDC 216
Query: 151 ASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDL 185
AS PC G C D V F C+C GYGG C+L L
Sbjct: 217 ASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELVL 251
Score = 100 bits (250), Expect = 7e-21
Identities = 71/213 (33%), Positives = 91/213 (42%), Gaps = 19/213 (8%)
Query: 1063 SPCLHDGACR-DLFDAFACACGPGWEGPRCEAHVDPCHSA--PCARGRCHTHPDG---RF 1116
SPC + G C D + C C PG+ G CE PC A PC G G F
Sbjct: 99 SPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNF 158
Query: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP 1176
CRC GF G RC + V +C + C +G+ C G +C C EG AG+ C +
Sbjct: 159 TCRCLVGFVGARCEVNVD--DCLMR-PCANGATCLDGINRFSCLCPEGFAGRFCTINLDD 215
Query: 1177 CEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGLPLPLP--------FPLLEVAVP 1228
C + PC G CR +C+C + + G+ CE+ LP+P P P V VP
Sbjct: 216 CASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELV--LPVPDPPTTVDTPLGPTSAVVVP 273
Query: 1229 AACACLLLLLLGLLSGILAARKRRQSEGTYSPS 1261
A GLL + RRQ G PS
Sbjct: 274 ATGPAPHSAGAGLLRISVKEVVRRQEAGLGEPS 306
Score = 85.5 bits (210), Expect = 3e-16
Identities = 60/202 (29%), Positives = 71/202 (35%), Gaps = 46/202 (22%)
Query: 1045 PGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDP------- 1097
PG P C A C DG+CR C PGWEG CE V
Sbjct: 20 PGQPVRADDCSSHCDLAHGCCAPDGSCR---------CDPGWEGLHCERCVRMPGCQHGT 70
Query: 1098 --------CHS-----------------APCAR-GRCHTHPDGRFECRCPPGFGGPRCRL 1131
CHS +PC G+C G + C C PGF G C
Sbjct: 71 CHQPWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCER 130
Query: 1132 PVPSKECSLNVTCLDGSPCEGGSPAA---NCSCLEGLAGQRCQVPTLPCEANPCLNGGTC 1188
E C +G C+ A C CL G G RC+V C PC NG TC
Sbjct: 131 KAGPCE-QAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATC 189
Query: 1189 RAAGGVSECICNARFSGQFCEV 1210
C+C F+G+FC +
Sbjct: 190 LDGINRFSCLCPEGFAGRFCTI 211
Score = 66.2 bits (160), Expect = 2e-10
Identities = 30/76 (39%), Positives = 39/76 (51%), Gaps = 2/76 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
C PC + C D + F+C C G+ G C ++D C S PC RG RC F+C
Sbjct: 178 CLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHD-FDC 236
Query: 1119 RCPPGFGGPRCRLPVP 1134
CP G+GG C L +P
Sbjct: 237 LCPSGYGGKTCELVLP 252
Score = 58.2 bits (139), Expect = 5e-08
Identities = 47/160 (29%), Positives = 59/160 (36%), Gaps = 14/160 (8%)
Query: 319 VEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVA 378
V D+C+S L G C P+G C C G+ G CE C+ P GTC
Sbjct: 24 VRADDCSSHCDLAHGCCA--PDG-SCRCDPGWEGLHCER----CVRMPGCQHGTCHQP-- 74
Query: 379 GYICRCPETWGGRDCSVQLTGCQGHT-CPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437
+ C C W G+ C C + C C+ G Y C C PG HG C +
Sbjct: 75 -WQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCM---YDGGGEYHCVCLPGFHGRDCER 130
Query: 438 NTTFSVMAGSPIQASVPAGGPLGLALRFRTTLPAGTLATR 477
AGSP + G AL F G + R
Sbjct: 131 KAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGAR 170
Score = 50.8 bits (120), Expect = 8e-06
Identities = 33/109 (30%), Positives = 43/109 (39%), Gaps = 17/109 (15%)
Query: 783 PLDNSSQPSELGGRQ------SWNLTAGC----------VSEDMCSPDPCFNGGTCLVTW 826
P + + P GG+ + N T C V+ D C PC NG TCL
Sbjct: 134 PCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGI 193
Query: 827 NDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCVAEATF 874
N F C CP F G C L C +PC A C + F C+ + +
Sbjct: 194 NRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGY 242
Score = 40.0 bits (92), Expect = 0.014
Identities = 17/47 (36%), Positives = 23/47 (48%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQP 852
++ D C+ PC G C +DF C CP+ + G TC L P P
Sbjct: 211 INLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELVLPVPDPP 257
Score = 35.4 bits (80), Expect = 0.35
Identities = 41/152 (26%), Positives = 51/152 (33%), Gaps = 32/152 (21%)
Query: 576 FAGCLQDVRVDGHLLLPEDLGENVLLGCER-----------------REQCRPLPCVHGG 618
F G +V VD L+ P G L G R + C PC G
Sbjct: 166 FVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGA 225
Query: 619 SCVDLWTHFRCDCARPHRGPTCADEIPA----ATFGLGGAPSSASFLLQELPGPNLTVSF 674
C D F C C + G TC +P T P+SA + P P+ +
Sbjct: 226 RCRDRVHDFDCLCPSGYGGKTCELVLPVPDPPTTVDTPLGPTSAVVVPATGPAPHSAGAG 285
Query: 675 LLR-------TRESAGLLLQFANDSAAGLTVF 699
LLR R+ AGL S L VF
Sbjct: 286 LLRISVKEVVRRQEAGL----GEPSLVALVVF 313
Score = 35.0 bits (79), Expect = 0.46
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 5/59 (8%)
Query: 808 EDMCSPD-PCFNGGTCLVTWN-DFHCTCPANFTGPTCAQQLW-C--PGQPCLPPATCEE 861
E +C+ PC NGG C+ ++HC C F G C ++ C G PC C++
Sbjct: 92 EHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQD 150
>gi|45545431 EGF-like-domain, multiple 9 [Homo sapiens]
Length = 383
Score = 169 bits (427), Expect = 2e-41
Identities = 102/299 (34%), Positives = 138/299 (46%), Gaps = 43/299 (14%)
Query: 134 CPLGYAGVTCEMEVDECASAPCLHGGSCL-DGVGSFRCVCAPGYGGTRCQLDLDECQSQP 192
C LG G + D+C+S L G C DG C C PG+ G C+ C P
Sbjct: 15 CILGAPGQP--VRADDCSSHCDLAHGCCAPDG----SCRCDPGWEGLHCE----RCVRMP 64
Query: 193 CAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECAS-APCEHNASCL-EGLGSFRCLCW 250
GTCH ++C C +G+ G C+++ C + +PC++ C+ +G G + C+C
Sbjct: 65 GCQHGTCHQ---PWQCICH-SGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCL 120
Query: 251 PGYSGELCEVDEDEC--ASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHC 308
PG+ G CE C A SPC++GG+C AL F C C
Sbjct: 121 PGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFAL------------------NFTCRC 162
Query: 309 PPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCL 368
GF GA C V VD+C RPC NG C D N F C CP+G+AG C ++D+C S PC
Sbjct: 163 LVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQ 222
Query: 369 HGGTCSDTVAGYICRCPETWGGRDCSVQL------TGCQGHTCPLAATCIPIFESGVHS 421
G C D V + C CP +GG+ C + L T P +A +P HS
Sbjct: 223 RGARCRDRVHDFDCLCPSGYGGKTCELVLPVPDPPTTVDTPLGPTSAVVVPATGPAPHS 281
Score = 165 bits (417), Expect = 3e-40
Identities = 130/403 (32%), Positives = 164/403 (40%), Gaps = 84/403 (20%)
Query: 186 DECQSQ-PCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAP-CEHNASCLEGLG 243
D+C S AHG D RCD G+EG HCER C P C+H +C +
Sbjct: 27 DDCSSHCDLAHGCCAPD--GSCRCD---PGWEGLHCER----CVRMPGCQHG-TCHQ--- 73
Query: 244 SFRCLCWPGYSGELCEVDEDECAS-SPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAA 302
++C+C G++G+ C+ DE C + SPCQ+GG+C+ Y G
Sbjct: 74 PWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCM-------YDG-------------GG 113
Query: 303 GFLCHCPPGFEGADCGVEVDEC--ASRPCLNGGHCQD---LPNGFQCHCPDGYAGPTCEE 357
+ C C PGF G DC + C A PC NGG CQD F C C G+ G CE
Sbjct: 114 EYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEV 173
Query: 358 DVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFES 417
+VD+CL PC +G TC D + + C CPE + GR C++ L C C A C
Sbjct: 174 NVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARC----RD 229
Query: 418 GVHSYVCHCPPGTHGPFC-------GQNTTFSVMAGSPIQASVPAGGPLGLALRFRTTLP 470
VH + C CP G G C TT G VPA GP
Sbjct: 230 RVHDFDCLCPSGYGGKTCELVLPVPDPPTTVDTPLGPTSAVVVPATGP--------APHS 281
Query: 471 AGTLATRNDTKESLELALVAATLQATLWSYSTTVLVLRLPDLALNDGHWHQVEVVLHLAT 530
AG R KE V +A L S LV+ + + L LAT
Sbjct: 282 AGAGLLRISVKE------VVRRQEAGLGEPSLVALVV-----------FGALTAALVLAT 324
Query: 531 --LELRLWHEG-CPARLCVAS----GPVALASTASATPLPAGI 566
L LR W G CP C P + LPAG+
Sbjct: 325 VLLTLRAWRRGVCPPGPCCYPAPHYAPACQDQECQVSMLPAGL 367
Score = 157 bits (398), Expect = 5e-38
Identities = 88/248 (35%), Positives = 116/248 (46%), Gaps = 45/248 (18%)
Query: 78 HGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRP-CHHGATCRNLADRYECHCPL 136
HG C P G C C PG++G CE C P C HG TC ++C C
Sbjct: 37 HGC-CAPDGS------CRCDPGWEGLHCE----RCVRMPGCQHG-TCH---QPWQCICHS 81
Query: 137 GYAGVTCEMEVDECAS-APCLHGGSCL-DGVGSFRCVCAPGYGGTRCQLDLDECQ--SQP 192
G+AG C+ + C + +PC +GG C+ DG G + CVC PG+ G C+ C+ P
Sbjct: 82 GWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSP 141
Query: 193 CAHGGTCHD---LVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLC 249
C +GG C D F C C G+ G CE V +C PC + A+CL+G+ F CLC
Sbjct: 142 CRNGGQCQDDQGFALNFTCRCL-VGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLC 200
Query: 250 WPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCP 309
G++G C ++ D+CAS PCQ G RC R F C CP
Sbjct: 201 PEGFAGRFCTINLDDCASRPCQRGARCRDR---------------------VHDFDCLCP 239
Query: 310 PGFEGADC 317
G+ G C
Sbjct: 240 SGYGGKTC 247
Score = 138 bits (347), Expect = 4e-32
Identities = 63/157 (40%), Positives = 86/157 (54%), Gaps = 9/157 (5%)
Query: 71 CATQ-PCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDEC--ASRPCHHGATCRN-- 125
C TQ PC +G C+ G + C C+PGF G CE C A PC +G C++
Sbjct: 95 CTTQSPCQNGGQCMYDGGGE--YHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQ 152
Query: 126 -LADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLD 184
A + C C +G+ G CE+ VD+C PC +G +CLDG+ F C+C G+ G C ++
Sbjct: 153 GFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTIN 212
Query: 185 LDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCE 221
LD+C S+PC G C D V+ F C C +GY G CE
Sbjct: 213 LDDCASRPCQRGARCRDRVHDFDCLCP-SGYGGKTCE 248
Score = 127 bits (320), Expect = 5e-29
Identities = 61/155 (39%), Positives = 78/155 (50%), Gaps = 18/155 (11%)
Query: 46 PCAPGTECQATESGGYTC---------------GPMEPRGCATQPCHHGALCVPQGPDPT 90
PC G +C G Y C GP E G PC +G C
Sbjct: 100 PCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAG---SPCRNGGQCQDDQGFAL 156
Query: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC 150
F C C+ GF G RCE+++D+C RPC +GATC + +R+ C CP G+AG C + +D+C
Sbjct: 157 NFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDC 216
Query: 151 ASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDL 185
AS PC G C D V F C+C GYGG C+L L
Sbjct: 217 ASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELVL 251
Score = 100 bits (250), Expect = 7e-21
Identities = 71/213 (33%), Positives = 91/213 (42%), Gaps = 19/213 (8%)
Query: 1063 SPCLHDGACR-DLFDAFACACGPGWEGPRCEAHVDPCHSA--PCARGRCHTHPDG---RF 1116
SPC + G C D + C C PG+ G CE PC A PC G G F
Sbjct: 99 SPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNF 158
Query: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP 1176
CRC GF G RC + V +C + C +G+ C G +C C EG AG+ C +
Sbjct: 159 TCRCLVGFVGARCEVNVD--DCLMR-PCANGATCLDGINRFSCLCPEGFAGRFCTINLDD 215
Query: 1177 CEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGLPLPLP--------FPLLEVAVP 1228
C + PC G CR +C+C + + G+ CE+ LP+P P P V VP
Sbjct: 216 CASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELV--LPVPDPPTTVDTPLGPTSAVVVP 273
Query: 1229 AACACLLLLLLGLLSGILAARKRRQSEGTYSPS 1261
A GLL + RRQ G PS
Sbjct: 274 ATGPAPHSAGAGLLRISVKEVVRRQEAGLGEPS 306
Score = 85.5 bits (210), Expect = 3e-16
Identities = 60/202 (29%), Positives = 71/202 (35%), Gaps = 46/202 (22%)
Query: 1045 PGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDP------- 1097
PG P C A C DG+CR C PGWEG CE V
Sbjct: 20 PGQPVRADDCSSHCDLAHGCCAPDGSCR---------CDPGWEGLHCERCVRMPGCQHGT 70
Query: 1098 --------CHS-----------------APCAR-GRCHTHPDGRFECRCPPGFGGPRCRL 1131
CHS +PC G+C G + C C PGF G C
Sbjct: 71 CHQPWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCER 130
Query: 1132 PVPSKECSLNVTCLDGSPCEGGSPAA---NCSCLEGLAGQRCQVPTLPCEANPCLNGGTC 1188
E C +G C+ A C CL G G RC+V C PC NG TC
Sbjct: 131 KAGPCE-QAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATC 189
Query: 1189 RAAGGVSECICNARFSGQFCEV 1210
C+C F+G+FC +
Sbjct: 190 LDGINRFSCLCPEGFAGRFCTI 211
Score = 66.2 bits (160), Expect = 2e-10
Identities = 30/76 (39%), Positives = 39/76 (51%), Gaps = 2/76 (2%)
Query: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
C PC + C D + F+C C G+ G C ++D C S PC RG RC F+C
Sbjct: 178 CLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHD-FDC 236
Query: 1119 RCPPGFGGPRCRLPVP 1134
CP G+GG C L +P
Sbjct: 237 LCPSGYGGKTCELVLP 252
Score = 58.2 bits (139), Expect = 5e-08
Identities = 47/160 (29%), Positives = 59/160 (36%), Gaps = 14/160 (8%)
Query: 319 VEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVA 378
V D+C+S L G C P+G C C G+ G CE C+ P GTC
Sbjct: 24 VRADDCSSHCDLAHGCCA--PDG-SCRCDPGWEGLHCER----CVRMPGCQHGTCHQP-- 74
Query: 379 GYICRCPETWGGRDCSVQLTGCQGHT-CPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437
+ C C W G+ C C + C C+ G Y C C PG HG C +
Sbjct: 75 -WQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCM---YDGGGEYHCVCLPGFHGRDCER 130
Query: 438 NTTFSVMAGSPIQASVPAGGPLGLALRFRTTLPAGTLATR 477
AGSP + G AL F G + R
Sbjct: 131 KAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGAR 170
Score = 50.8 bits (120), Expect = 8e-06
Identities = 33/109 (30%), Positives = 43/109 (39%), Gaps = 17/109 (15%)
Query: 783 PLDNSSQPSELGGRQ------SWNLTAGC----------VSEDMCSPDPCFNGGTCLVTW 826
P + + P GG+ + N T C V+ D C PC NG TCL
Sbjct: 134 PCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGI 193
Query: 827 NDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCVAEATF 874
N F C CP F G C L C +PC A C + F C+ + +
Sbjct: 194 NRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGY 242
Score = 40.0 bits (92), Expect = 0.014
Identities = 17/47 (36%), Positives = 23/47 (48%)
Query: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQP 852
++ D C+ PC G C +DF C CP+ + G TC L P P
Sbjct: 211 INLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELVLPVPDPP 257
Score = 35.4 bits (80), Expect = 0.35
Identities = 41/152 (26%), Positives = 51/152 (33%), Gaps = 32/152 (21%)
Query: 576 FAGCLQDVRVDGHLLLPEDLGENVLLGCER-----------------REQCRPLPCVHGG 618
F G +V VD L+ P G L G R + C PC G
Sbjct: 166 FVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGA 225
Query: 619 SCVDLWTHFRCDCARPHRGPTCADEIPA----ATFGLGGAPSSASFLLQELPGPNLTVSF 674
C D F C C + G TC +P T P+SA + P P+ +
Sbjct: 226 RCRDRVHDFDCLCPSGYGGKTCELVLPVPDPPTTVDTPLGPTSAVVVPATGPAPHSAGAG 285
Query: 675 LLR-------TRESAGLLLQFANDSAAGLTVF 699
LLR R+ AGL S L VF
Sbjct: 286 LLRISVKEVVRRQEAGL----GEPSLVALVVF 313
Score = 35.0 bits (79), Expect = 0.46
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 5/59 (8%)
Query: 808 EDMCSPD-PCFNGGTCLVTWN-DFHCTCPANFTGPTCAQQLW-C--PGQPCLPPATCEE 861
E +C+ PC NGG C+ ++HC C F G C ++ C G PC C++
Sbjct: 92 EHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQD 150
>gi|74136023 delta-like 1 homolog [Homo sapiens]
Length = 383
Score = 157 bits (396), Expect = 8e-38
Identities = 89/249 (35%), Positives = 115/249 (46%), Gaps = 33/249 (13%)
Query: 149 ECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRC 208
EC A G C D C C PG+ G C D+C + P G C + +C
Sbjct: 25 ECFPACNPQNGFCED---DNVCRCQPGWQGPLC----DQCVTSPGCLHGLCGE---PGQC 74
Query: 209 DCAGTGYEGTHCEREVLECASAPCEHNASCLE-GLGSFRCLCWPGYSGELCEVDEDECA- 266
C G++G C+R+V C+SAPC +N +C+ G + C C PGYSG+ C+ + C
Sbjct: 75 ICTD-GWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVI 133
Query: 267 -SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECA 325
SPCQHGG C+ A HA+ C CPPGF G C + + C
Sbjct: 134 NGSPCQHGGTCVDDEGRA---------------SHAS---CLCPPGFSGNFCEIVANSCT 175
Query: 326 SRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTC-SDTVAGYICRC 384
PC N G C D+ F+C CP G+ TC V C S PC +GGTC T Y C C
Sbjct: 176 PNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLC 235
Query: 385 PETWGGRDC 393
+ G C
Sbjct: 236 KPEFTGLTC 244
Score = 149 bits (375), Expect = 2e-35
Identities = 88/252 (34%), Positives = 112/252 (44%), Gaps = 41/252 (16%)
Query: 78 HGALCVPQGPDPTGFR-----CYCVPGFQGPRCELDIDECASRP-CHHGATCRNLADRYE 131
+GA C P GF C C PG+QGP C D+C + P C HG + +
Sbjct: 22 YGAECFPACNPQNGFCEDDNVCRCQPGWQGPLC----DQCVTSPGCLHGL----CGEPGQ 73
Query: 132 CHCPLGYAGVTCEMEVDECASAPCLHGGSCLD-GVGSFRCVCAPGYGGTRCQLDLDEC-- 188
C C G+ G C+ +V C+SAPC + G+C+ G + C CAPGY G CQ C
Sbjct: 74 CICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVI 133
Query: 189 QSQPCAHGGTCHD---LVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSF 245
PC HGGTC D + C C G+ G CE C PCE++ C + G F
Sbjct: 134 NGSPCQHGGTCVDDEGRASHASCLCP-PGFSGNFCEIVANSCTPNPCENDGVCTDIGGDF 192
Query: 246 RCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFL 305
RC C G+ + C CASSPCQ+GG CLQ + +
Sbjct: 193 RCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQ--------------------VSYE 232
Query: 306 CHCPPGFEGADC 317
C C P F G C
Sbjct: 233 CLCKPEFTGLTC 244
Score = 123 bits (308), Expect = 1e-27
Identities = 89/286 (31%), Positives = 123/286 (43%), Gaps = 51/286 (17%)
Query: 187 ECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSF- 245
EC G C D N RC G++G C+ +C ++P CL GL
Sbjct: 25 ECFPACNPQNGFCED-DNVCRCQ---PGWQGPLCD----QCVTSP-----GCLHGLCGEP 71
Query: 246 -RCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGF 304
+C+C G+ GELC+ D C+S+PC + G C+ D LY
Sbjct: 72 GQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDD-GLYE------------------ 112
Query: 305 LCHCPPGFEGADCGVEVDECA--SRPCLNGGHCQD---LPNGFQCHCPDGYAGPTCEEDV 359
C C PG+ G DC + C PC +GG C D + C CP G++G CE
Sbjct: 113 -CSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVA 171
Query: 360 DECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGV 419
+ C +PC + G C+D + CRCP + + CS +T C C TC+ +
Sbjct: 172 NSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCL---QHTQ 228
Query: 420 HSYVCHCPPGTHGPFCGQNTTFSVMAGSPIQAS-VPAGGPLGLALR 464
SY C C P G C + A SP Q + +P+G GLA R
Sbjct: 229 VSYECLCKPEFTGLTCVKK-----RALSPQQVTRLPSG--YGLAYR 267
Score = 110 bits (274), Expect = 1e-23
Identities = 53/157 (33%), Positives = 70/157 (44%), Gaps = 19/157 (12%)
Query: 41 ACASDPCAPGTECQATESGGYTC---------------GPMEPRGCATQPCHHGALCVPQ 85
AC+S PCA C + + G Y C GP G PC HG CV
Sbjct: 91 ACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVING---SPCQHGGTCVDD 147
Query: 86 GPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEM 145
+ C C PGF G CE+ + C PC + C ++ + C CP G+ TC
Sbjct: 148 EGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSR 207
Query: 146 EVDECASAPCLHGGSCLDGVG-SFRCVCAPGYGGTRC 181
V CAS+PC +GG+CL S+ C+C P + G C
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
Score = 107 bits (268), Expect = 6e-23
Identities = 57/176 (32%), Positives = 76/176 (43%), Gaps = 10/176 (5%)
Query: 42 CASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQ 101
C C +C T+ + R C++ PC + CV D + C C PG+
Sbjct: 63 CLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGTCVSL--DDGLYECSCAPGYS 120
Query: 102 GPRCELDIDECA--SRPCHHGATC---RNLADRYECHCPLGYAGVTCEMEVDECASAPCL 156
G C+ C PC HG TC A C CP G++G CE+ + C PC
Sbjct: 121 GKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCE 180
Query: 157 HGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTC--HDLVNGFRCDC 210
+ G C D G FRC C G+ C + C S PC +GGTC H V+ + C C
Sbjct: 181 NDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVS-YECLC 235
Score = 104 bits (259), Expect = 6e-22
Identities = 58/156 (37%), Positives = 73/156 (46%), Gaps = 14/156 (8%)
Query: 1060 CAPSP-CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTHPDGRFE 1117
C SP CLH G C + C C GW+G C+ V C SAPCA G C + DG +E
Sbjct: 57 CVTSPGCLH-GLCGE---PGQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYE 112
Query: 1118 CRCPPGFGGPRCRLP-----VPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQV 1172
C C PG+ G C+ + C TC+D EG + A+C C G +G C++
Sbjct: 113 CSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDD---EGRASHASCLCPPGFSGNFCEI 169
Query: 1173 PTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
C NPC N G C GG C C A F + C
Sbjct: 170 VANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTC 205
Score = 100 bits (250), Expect = 7e-21
Identities = 56/167 (33%), Positives = 76/167 (45%), Gaps = 10/167 (5%)
Query: 1055 RGAPVCAPSPCLHDGACRDLFDA-FACACGPGWEGPRCEAHVDPC--HSAPCARGRCHTH 1111
R C+ +PC ++G C L D + C+C PG+ G C+ PC + +PC G
Sbjct: 87 RDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVD 146
Query: 1112 PDGRFE---CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQ 1168
+GR C CPPGF G C + S C+ N C + C C C G +
Sbjct: 147 DEGRASHASCLCPPGFSGNFCEIVANS--CTPN-PCENDGVCTDIGGDFRCRCPAGFIDK 203
Query: 1169 RCQVPTLPCEANPCLNGGTCRAAGGVS-ECICNARFSGQFCEVAKGL 1214
C P C ++PC NGGTC VS EC+C F+G C + L
Sbjct: 204 TCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKKRAL 250
Score = 52.0 bits (123), Expect = 4e-06
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLW-CPGQPCLPPATC-EEVPDGFVC 868
C+P+PC N G C DF C CPA F TC++ + C PC TC + + C
Sbjct: 174 CTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYEC 233
Query: 869 VAEATF 874
+ + F
Sbjct: 234 LCKPEF 239
Score = 46.6 bits (109), Expect = 2e-04
Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 13/93 (13%)
Query: 781 PLPLDNSSQPSELGGRQSWNLTAGCVSEDM------CSPDPCFNGGTCLV-TWNDFHCTC 833
P P +N +++GG AG + + C+ PC NGGTCL T + C C
Sbjct: 176 PNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLC 235
Query: 834 PANFTGPTCAQQLWCPGQPCLPPATCEEVPDGF 866
FTG TC + + L P +P G+
Sbjct: 236 KPEFTGLTCVK------KRALSPQQVTRLPSGY 262
Score = 36.2 bits (82), Expect = 0.21
Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 6/54 (11%)
Query: 811 CSPDPCFNGGTCLVTWND--FHCTCPANFTGPTCAQQ---LWCPGQPCLPPATC 859
CS PC N GTC V+ +D + C+C ++G C ++ G PC TC
Sbjct: 92 CSSAPCANNGTC-VSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTC 144
Score = 34.3 bits (77), Expect = 0.79
Identities = 20/64 (31%), Positives = 26/64 (40%), Gaps = 4/64 (6%)
Query: 815 PCFNGGTCL---VTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFVCVA 870
PC +GGTC+ + C CP F+G C C PC C ++ F C
Sbjct: 137 PCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRC 196
Query: 871 EATF 874
A F
Sbjct: 197 PAGF 200
Score = 33.1 bits (74), Expect = 1.8
Identities = 13/33 (39%), Positives = 16/33 (48%)
Query: 609 CRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCA 641
C P PC + G C D+ FRC C TC+
Sbjct: 174 CTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCS 206
>gi|194328809 latent transforming growth factor beta binding protein
3 isoform 1 [Homo sapiens]
Length = 1303
Score = 153 bits (387), Expect = 9e-37
Identities = 112/342 (32%), Positives = 154/342 (45%), Gaps = 61/342 (17%)
Query: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGP---RCELDIDECASRPCHHG-ATCRNLADRYE 131
C HG CVP PD + C+C PG++ R +D++EC + PC G C N Y
Sbjct: 585 CGHGE-CVPGPPD---YSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYN 640
Query: 132 CHCPLGY-----AGVTCEMEVDECASAP-CLHGGSCLDGVGSFRCVCAPGYG--GTR--- 180
CHC GY AG ++++ECA C GG C++ G ++C C PGY +R
Sbjct: 641 CHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPV 700
Query: 181 CQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGY--EGTHCEREVLECAS-APCEHNAS 237
C+ D+DEC+ G C + F+C GY +G R+V ECA +PC
Sbjct: 701 CE-DIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGW- 758
Query: 238 CLEGLGSFRCLCWPGYS----GELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFP 293
C GSFRC C GY+ G C +D DEC + G C P
Sbjct: 759 CENLPGSFRCTCAQGYAPAPDGRSC-LDVDECEAGDVCDNGICSNT-------------P 804
Query: 294 GAFSFRHAAGFLCHCPPGF----EGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDG 349
G+F C C G+ + + C ++DEC GG C + ++C CP G
Sbjct: 805 GSFQ--------CQCLSGYHLSRDRSHCE-DIDECDFPAACIGGDCINTNGSYRCLCPQG 855
Query: 350 Y---AGPTCEEDVDECLSDP--CLHGGTCSDTVAGYICRCPE 386
+ G C +D+DEC DP CL G C + Y+C C E
Sbjct: 856 HRLVGGRKC-QDIDECSQDPSLCLPHGACKNLQGSYVCVCDE 896
Score = 123 bits (308), Expect = 1e-27
Identities = 127/470 (27%), Positives = 171/470 (36%), Gaps = 97/470 (20%)
Query: 42 CASDPCAPGTECQATESGGYTC---------------GPMEPRGCA-TQPCHHGALCVPQ 85
C ++PC PG G Y C ++ CA C G C+
Sbjct: 620 CEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCI-- 677
Query: 86 GPDPTGFRCYCVPGF-----QGPRCELDIDECASRPCHHGATCRNLADRYEC-HCPLGY- 138
P ++C C PG+ + P CE DIDEC C N ++C C GY
Sbjct: 678 -NFPGHYKCNCYPGYRLKASRPPVCE-DIDECRDPSSCPDGKCENKPGSFKCIACQPGYR 735
Query: 139 --AGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYG----GTRCQLDLDECQSQP 192
G C +V+ECA G C + GSFRC CA GY G C LD+DEC++
Sbjct: 736 SQGGGACR-DVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSC-LDVDECEAGD 793
Query: 193 CAHGGTCHDLVNGFRCDCAGTGY----EGTHCEREVLECASAPCEHNASCLEGLGSFRCL 248
G C + F+C C +GY + +HCE ++ EC C+ GS+RCL
Sbjct: 794 VCDNGICSNTPGSFQCQCL-SGYHLSRDRSHCE-DIDECDFPAACIGGDCINTNGSYRCL 851
Query: 249 CWPGY---SGELCEVDEDECASSP--CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAG 303
C G+ G C+ D DEC+ P C G C L G F+
Sbjct: 852 CPQGHRLVGGRKCQ-DIDECSQDPSLCLPHGACKN-----LQGSYVCVCDEGFTPTQDQH 905
Query: 304 FLCHCPPGFEGADCGVEVDE-----------------CASRPCLNGGHCQDLP------N 340
+C + D+ C S G HC+ P
Sbjct: 906 GCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSA 965
Query: 341 GFQCHCPDGYA----------GPTCEEDVDECL---SDPCLHGGTCSDTVAGYICRCPET 387
F CPDG G D+DEC+ S+ C G C +T GY C C +
Sbjct: 966 EFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKE-GKCVNTQPGYECYCKQG 1024
Query: 388 W---GGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHC-PPGTHGP 433
+ G V + C + C E+ Y C C PP + P
Sbjct: 1025 FYYDGNLLECVDVDECLDESNCRNGVC----ENTRGGYRCACTPPAEYSP 1070
Score = 123 bits (308), Expect = 1e-27
Identities = 121/422 (28%), Positives = 163/422 (38%), Gaps = 73/422 (17%)
Query: 39 PSACASDPCA--PGT-ECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPD--PTGFR 93
PS+C C PG+ +C A + G + G R C G+ C P + P FR
Sbjct: 710 PSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRD--VNECAEGSPCSPGWCENLPGSFR 767
Query: 94 CYCVPGF----QGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVTCEM 145
C C G+ G C LD+DEC + C N ++C C GY CE
Sbjct: 768 CTCAQGYAPAPDGRSC-LDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCE- 825
Query: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGY---GGTRCQLDLDECQSQP--CAHGGTCH 200
++DEC GG C++ GS+RC+C G+ GG +CQ D+DEC P C G C
Sbjct: 826 DIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQ-DIDECSQDPSLCLPHGACK 884
Query: 201 DLVNGFRCDCAGTGYEGTH----CEREVLECASAPCEHN--------ASCLEGLGSFRCL 248
+L + C C G+ T CE C N + + C
Sbjct: 885 NLQGSYVCVC-DEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECC 943
Query: 249 CWPGYS-GELCEVDEDECASSP-----CQHGGRCLQRSDPALYG-------------GVQ 289
C G G+ CE+ SS C G Q ++ YG G +
Sbjct: 944 CSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSE 1003
Query: 290 AAFPGAFSFRHAAGFLCHCPPGF--EG--ADCGVEVDECASRPCLNGGHCQDLPNGFQCH 345
G G+ C+C GF +G +C V+VDEC G C++ G++C
Sbjct: 1004 ICKEGK-CVNTQPGYECYCKQGFYYDGNLLEC-VDVDECLDESNCRNGVCENTRGGYRCA 1061
Query: 346 C--PDGY--AGPTC----EEDVDECLSDPCLHGGTCSDTVAGYICRCPETW----GGRDC 393
C P Y A C E DVDEC G C + Y C C W GRDC
Sbjct: 1062 CTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDC 1121
Query: 394 SV 395
+
Sbjct: 1122 QL 1123
Score = 119 bits (298), Expect = 2e-26
Identities = 125/439 (28%), Positives = 169/439 (38%), Gaps = 77/439 (17%)
Query: 60 GYTCGPMEPRGCAT-QPCHHGALCVPQGP---DPTGFRCY-CVPGF--QGPRCELDIDEC 112
GY P C C + C P G P F+C C PG+ QG D++EC
Sbjct: 690 GYRLKASRPPVCEDIDECRDPSSC-PDGKCENKPGSFKCIACQPGYRSQGGGACRDVNEC 748
Query: 113 AS-RPCHHGATCRNLADRYECHCPLGYA----GVTCEMEVDECASAPCLHGGSCLDGVGS 167
A PC G C NL + C C GYA G +C ++VDEC + G C + GS
Sbjct: 749 AEGSPCSPG-WCENLPGSFRCTCAQGYAPAPDGRSC-LDVDECEAGDVCDNGICSNTPGS 806
Query: 168 FRCVCAPGYGGTR----CQLDLDECQSQPCAHGGTCHDLVNGFRCDCA-GTGYEGTHCER 222
F+C C GY +R C+ D+DEC GG C + +RC C G G +
Sbjct: 807 FQCQCLSGYHLSRDRSHCE-DIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQ 865
Query: 223 EVLECASAP--CEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECAS-SPCQHGGRCLQR 279
++ EC+ P C + +C GS+ C+C G++ D+ C H C
Sbjct: 866 DIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQ---DQHGCEEVEQPHHKKECYLN 922
Query: 280 SDPALYGGVQAAFP----------GAFSFRHAAGFLCH----------CPPGFE------ 313
D ++ A GA H + C CP G
Sbjct: 923 FDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNN 982
Query: 314 ----GADCGVEVDEC---ASRPCLNGGHCQDLPNGFQCHCPDG--YAGPTCE-EDVDECL 363
G ++DEC S C G C + G++C+C G Y G E DVDECL
Sbjct: 983 IVNYGIPAHRDIDECMLFGSEICKEG-KCVNTQPGYECYCKQGFYYDGNLLECVDVDECL 1041
Query: 364 SDPCLHGGTCSDTVAGYICRC--PETW--GGRDC----SVQLTGCQGHTCPLAATCIPIF 415
+ G C +T GY C C P + R C + + CQ C+ +
Sbjct: 1042 DESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNL- 1100
Query: 416 ESGVHSYVCHC-PPGTHGP 433
SY C C PP GP
Sbjct: 1101 ---PGSYRCECRPPWVPGP 1116
Score = 118 bits (295), Expect = 4e-26
Identities = 96/311 (30%), Positives = 133/311 (42%), Gaps = 56/311 (18%)
Query: 146 EVDECASAPCLHG-GSCLDGVGSFRCVCAPGYGGT---RCQLDLDECQSQPCAHG-GTCH 200
E DEC + G G C+ G + C C PGY R +D++EC+++PC G G C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 201 DLVNGFRCDCAGTGYE------GTHCEREVLECASAP-CEHNASCLEGLGSFRCLCWPGY 253
+ + C C GY G C ++ ECA C C+ G ++C C+PGY
Sbjct: 634 NTGGSYNCHC-NRGYRLHVGAGGRSCV-DLNECAKPHLCGDGGFCINFPGHYKCNCYPGY 691
Query: 254 SGE-----LCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHC 308
+ +CE D DEC G+C + PG+F C
Sbjct: 692 RLKASRPPVCE-DIDECRDPSSCPDGKCENK-------------PGSFK-------CIAC 730
Query: 309 PPGFEGADCGV--EVDECASRPCLNGGHCQDLPNGFQCHCPDGYA----GPTCEEDVDEC 362
PG+ G +V+ECA + G C++LP F+C C GYA G +C DVDEC
Sbjct: 731 QPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSC-LDVDEC 789
Query: 363 LSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQG-HTCPLAATCIP---IFESG 418
+ G CS+T + C+C G S + C+ C A CI I +G
Sbjct: 790 EAGDVCDNGICSNTPGSFQCQC---LSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNG 846
Query: 419 VHSYVCHCPPG 429
SY C CP G
Sbjct: 847 --SYRCLCPQG 855
Score = 81.6 bits (200), Expect = 4e-15
Identities = 89/355 (25%), Positives = 124/355 (34%), Gaps = 64/355 (18%)
Query: 134 CPLGYAGVTCE--MEVDECASAPCLHGGSCLDGVGSFRCVCAPGY----GGTRCQLDLDE 187
CP GY + +++ECA G CL+ GS+RCVC PG+ T+C D E
Sbjct: 341 CPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPE 400
Query: 188 CQS---------QPCAHGGT--------CHDLVNGFRCDCAGTGYEGTHCEREVLECASA 230
+S C H T C + + C +GT +E+
Sbjct: 401 EKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKG 460
Query: 231 ---PCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQ--------------HG 273
H ++G F P + ++ E + P +
Sbjct: 461 YHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSE 520
Query: 274 GRCLQRSDPALYGGVQAAFPGAFSFRH---AAGFLCHCPPGFEGADCG----VEVDECAS 326
R +Q+S P +P S FL PP + E DEC
Sbjct: 521 ERSVQQSHPTATTTPARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRL 580
Query: 327 RPCLNG-GHCQDLPNGFQCHCPDGYAGPTCEE---DVDECLSDPCLHG-GTCSDTVAGYI 381
+ G G C P + CHC GY DV+EC ++PC G G C +T Y
Sbjct: 581 NQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYN 640
Query: 382 CRCPETW------GGRDCSVQLTGC-QGHTCPLAATCIPIFESGVHSYVCHCPPG 429
C C + GGR C V L C + H C CI + Y C+C PG
Sbjct: 641 CHCNRGYRLHVGAGGRSC-VDLNECAKPHLCGDGGFCI----NFPGHYKCNCYPG 690
Score = 80.9 bits (198), Expect = 7e-15
Identities = 99/391 (25%), Positives = 137/391 (35%), Gaps = 67/391 (17%)
Query: 42 CASDP--CAPGTECQATESGGYTC-------GPMEPRGC--ATQPCHHGALCVPQGPDPT 90
C+ DP C P C+ + G Y C + GC QP HH C D
Sbjct: 870 CSQDPSLCLPHGACKNLQ-GSYVCVCDEGFTPTQDQHGCEEVEQP-HHKKECYLNFDDTV 927
Query: 91 GFRCYCVPGFQGPRCELDI-----DECASRPCHHGATCRNLADRYECHCPLGYA------ 139
C + D C PC ++ + CP G
Sbjct: 928 FCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAE-----FHSLCPDGKGYTQDNN 982
Query: 140 ----GVTCEMEVDECA--SAPCLHGGSCLDGVGSFRCVCAPG--YGGTRCQ-LDLDECQS 190
G+ ++DEC + G C++ + C C G Y G + +D+DEC
Sbjct: 983 IVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLD 1042
Query: 191 QPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVL---ECASAPCEHNASCLEGL----- 242
+ G C + G+RC C E + +R+ L E C+ A+C G
Sbjct: 1043 ESNCRNGVCENTRGGYRCACTPPA-EYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLP 1101
Query: 243 GSFRCLC---W-PGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSF 298
GS+RC C W PG SG C++ E +P + QR + + G A A +F
Sbjct: 1102 GSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAG--PALTF 1159
Query: 299 RHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHC---QDLPNGFQCHCPDGYAGPTC 355
C C +G G + C R G HC Q N F P P
Sbjct: 1160 DD-----CCCR---QGRGWGAQCRPCPPRGA--GSHCPTSQSESNSFWDTSPLLLGKPPR 1209
Query: 356 EEDVDECLSDPC-LHGGTCSDTVAGYICRCP 385
+ED E SD C G C G +C CP
Sbjct: 1210 DEDSSEEDSDECRCVSGRCVPRPGGAVCECP 1240
Score = 75.9 bits (185), Expect = 2e-13
Identities = 94/317 (29%), Positives = 115/317 (36%), Gaps = 73/317 (23%)
Query: 76 CHHGALCVPQGPDPTGFRCYCVPGF--QGPRCE-LDIDECASRPCHHGATCRNLADRYEC 132
C G CV P G+ CYC GF G E +D+DEC C N Y C
Sbjct: 1005 CKEGK-CVNTQP---GYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRC 1060
Query: 133 HC--PLGYAGVT--C----EMEVDECASAPCLHGGSCLDGVGSFRCVC----APGYGGTR 180
C P Y+ C EM+VDEC G C++ GS+RC C PG G
Sbjct: 1061 ACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRD 1120
Query: 181 CQLD----------LDECQSQPCAHGGTCHDLVNG-----FRCDC-AGTGYEGTHCEREV 224
CQL D C SQ G C + G C C G G+ G C
Sbjct: 1121 CQLPESPAERAPERRDVCWSQR-GEDGMCAGPLAGPALTFDDCCCRQGRGW-GAQCRPCP 1178
Query: 225 LECASAPCEHNASCLEGL--GSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDP 282
A + C + S S L P + E D DEC GRC+ R
Sbjct: 1179 PRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCV----SGRCVPR--- 1231
Query: 283 ALYGGVQAAFPGAFSFRHAAGFLCHCPPGFE----GADCGVEVDECA---SRPCL-NGGH 334
PG G +C CP GF+ A C V++DEC R L
Sbjct: 1232 ----------PG--------GAVCECPGGFQLDASRARC-VDIDECRELNQRGLLCKSER 1272
Query: 335 CQDLPNGFQCHCPDGYA 351
C + F+C C G+A
Sbjct: 1273 CVNTSGSFRCVCKAGFA 1289
Score = 67.4 bits (163), Expect = 8e-11
Identities = 57/183 (31%), Positives = 80/183 (43%), Gaps = 18/183 (9%)
Query: 1035 PGAREHFASWPGTPAPILG-CRGAPVCAP-SPCLHDGACRDLFDAFACACGPGW----EG 1088
PG+ + A PG + G CR CA SPC G C +L +F C C G+ +G
Sbjct: 722 PGSFKCIACQPGYRSQGGGACRDVNECAEGSPC-SPGWCENLPGSFRCTCAQGYAPAPDG 780
Query: 1089 PRCEAHVDPCHSAP-CARGRCHTHPDGRFECRCPPGFGGPRCRLPVPS-KECSLNVTCLD 1146
C VD C + C G C P G F+C+C G+ R R EC C+
Sbjct: 781 RSC-LDVDECEAGDVCDNGICSNTP-GSFQCQCLSGYHLSRDRSHCEDIDECDFPAACI- 837
Query: 1147 GSPCEGGSPAANCSCLEG---LAGQRCQVPTLPCEANP--CLNGGTCRAAGGVSECICNA 1201
G C + + C C +G + G++CQ C +P CL G C+ G C+C+
Sbjct: 838 GGDCINTNGSYRCLCPQGHRLVGGRKCQ-DIDECSQDPSLCLPHGACKNLQGSYVCVCDE 896
Query: 1202 RFS 1204
F+
Sbjct: 897 GFT 899
Score = 43.1 bits (100), Expect = 0.002
Identities = 42/159 (26%), Positives = 58/159 (36%), Gaps = 15/159 (9%)
Query: 1054 CRGAPVCAPSPCLHD-GACRDLFDAFACACGPGWE-----GPRCEAHVDPCHSAP-CARG 1106
C C PC G C + ++ C C G+ G R ++ C C G
Sbjct: 614 CVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDG 673
Query: 1107 RCHTHPDGRFECRCPPGFGGPRCRLPV--PSKECSLNVTCLDGSPCEGGSPAANC-SCLE 1163
+ G ++C C PG+ R PV EC +C DG CE + C +C
Sbjct: 674 GFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGK-CENKPGSFKCIACQP 732
Query: 1164 GL---AGQRCQVPTLPCEANPCLNGGTCRAAGGVSECIC 1199
G G C+ E +PC + G C G C C
Sbjct: 733 GYRSQGGGACRDVNECAEGSPC-SPGWCENLPGSFRCTC 770
Score = 42.0 bits (97), Expect = 0.004
Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 12/86 (13%)
Query: 1132 PVPSKECSLNVTCLDGSPCEGGSPAA----NCSCLEGLAGQRCQVPTLPCEANPCLNGGT 1187
PV K L C D C+ GS N + L G +V P PC+NGG
Sbjct: 68 PVICKRTCLKGQCRDS--CQQGSNMTLIGENGHSTDTLTGSGFRVVVCPL---PCMNGGQ 122
Query: 1188 CRAAGGVSECICNARFSGQFCEVAKG 1213
C + ++C+C F+G+FC+V G
Sbjct: 123 CSSR---NQCLCPPDFTGRFCQVPAG 145
Score = 41.6 bits (96), Expect = 0.005
Identities = 32/94 (34%), Positives = 38/94 (40%), Gaps = 12/94 (12%)
Query: 1051 ILGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWE----GPRC----EAHVDPCHS-A 1101
+L C C +G C + + CAC P E +C E VD C A
Sbjct: 1031 LLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPA 1090
Query: 1102 PCARGRCHTHPDG-RFECRCP--PGFGGPRCRLP 1132
C GRC P R ECR P PG G C+LP
Sbjct: 1091 ACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLP 1124
Score = 40.8 bits (94), Expect = 0.008
Identities = 56/237 (23%), Positives = 79/237 (33%), Gaps = 37/237 (15%)
Query: 40 SACASDPCAPGTECQATESGGYTCGPM-EPRGCAT-QPCHHGALCVPQGPDPTGFRCYCV 97
S A P AP + A++ Y + +P G P H A VP GP
Sbjct: 165 STGALPPLAPEGDSVASKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAP 224
Query: 98 PGFQG------PRCELDIDECASRPCHHGATCRNLAD-------RYECHCPLGYAGVTCE 144
P P + + S A ++L R PLG
Sbjct: 225 PPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLG------R 278
Query: 145 MEVDECASAPCLHGGSCLDGVGSFRCVCAP---GYGGTRC----QLDLDECQSQPCAHGG 197
D PC G + L G+ C +G ++C QL Q G
Sbjct: 279 CFQDTLPKQPC--GSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGE 336
Query: 198 TCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYS 254
D G++ THC+ ++ ECA + CL GS+RC+C PG+S
Sbjct: 337 VGADCPQGYK------RLNSTHCQ-DINECAMPGVCRHGDCLNNPGSYRCVCPPGHS 386
Score = 40.4 bits (93), Expect = 0.011
Identities = 25/68 (36%), Positives = 26/68 (38%), Gaps = 4/68 (5%)
Query: 1137 ECSLNVTCLDGSPCEGGSPAANCSCLEGLAG---QRCQVPTLPCEANPCLNG-GTCRAAG 1192
EC LN C G P +C C G R V CEA PC G G C G
Sbjct: 577 ECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTG 636
Query: 1193 GVSECICN 1200
G C CN
Sbjct: 637 GSYNCHCN 644
Score = 39.7 bits (91), Expect = 0.019
Identities = 35/128 (27%), Positives = 53/128 (41%), Gaps = 16/128 (12%)
Query: 1068 DGACRDLFDAFACACGPG--WEGPRCEA-HVDPC-HSAPCARGRCHTHPDGRFECRC-PP 1122
+G C + + C C G ++G E VD C + C G C + G + C C PP
Sbjct: 1007 EGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCE-NTRGGYRCACTPP 1065
Query: 1123 GFGGPRCRLPVPSKECSLNVTCLDGSPCEGGS-----PAANCSC----LEGLAGQRCQVP 1173
P R + +E ++ C D + C G + C C + G +G+ CQ+P
Sbjct: 1066 AEYSPAQRQCLSPEEMDVD-ECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLP 1124
Query: 1174 TLPCEANP 1181
P E P
Sbjct: 1125 ESPAERAP 1132
Score = 38.9 bits (89), Expect = 0.032
Identities = 43/162 (26%), Positives = 57/162 (35%), Gaps = 23/162 (14%)
Query: 262 EDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCG--V 319
ED C S G + Y GVQ P R G CP G++ +
Sbjct: 301 EDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGP----VRGEVG--ADCPQGYKRLNSTHCQ 354
Query: 320 EVDECASRPCLNGGHCQDLPNGFQCHCPDGYA-GPT---CEEDVDE----CL-----SDP 366
+++ECA G C + P ++C CP G++ GP+ C D E C
Sbjct: 355 DINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQ 414
Query: 367 CLHGGTCSDTVAGYICRCPETWGGR--DCSVQLTGCQGHTCP 406
C H T T C + WG R C T CP
Sbjct: 415 CQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICP 456
Score = 38.9 bits (89), Expect = 0.032
Identities = 22/75 (29%), Positives = 28/75 (37%), Gaps = 5/75 (6%)
Query: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT---GPTCAQQLWCPGQP--CLPPATC 859
C D C GG C+ T + C CP G C C P CLP C
Sbjct: 824 CEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGAC 883
Query: 860 EEVPDGFVCVAEATF 874
+ + +VCV + F
Sbjct: 884 KNLQGSYVCVCDEGF 898
Score = 36.6 bits (83), Expect = 0.16
Identities = 41/159 (25%), Positives = 54/159 (33%), Gaps = 30/159 (18%)
Query: 35 PSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGF-- 92
P P+ D C C+ G C P PRG G+ C + F
Sbjct: 1151 PLAGPALTFDDCC-----CRQGRGWGAQCRPCPPRGA-------GSHCPTSQSESNSFWD 1198
Query: 93 ---RCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGY----AGVTCEM 145
P E D DEC C G C C CP G+ + C +
Sbjct: 1199 TSPLLLGKPPRDEDSSEEDSDECR---CVSGR-CVPRPGGAVCECPGGFQLDASRARC-V 1253
Query: 146 EVDECASAP----CLHGGSCLDGVGSFRCVCAPGYGGTR 180
++DEC C++ GSFRCVC G+ +R
Sbjct: 1254 DIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSR 1292
Score = 35.4 bits (80), Expect = 0.35
Identities = 50/235 (21%), Positives = 72/235 (30%), Gaps = 63/235 (26%)
Query: 1054 CRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWEGPR----CEAHVDPCHSAPCARG- 1106
C+ C+ PS CL GAC++L ++ C C G+ + CE P H C
Sbjct: 864 CQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNF 923
Query: 1107 ----------------------------------RCHTHPDGRFECRCPPGFGGPR---- 1128
C + F CP G G +
Sbjct: 924 DDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNI 983
Query: 1129 CRLPVPS----KECSL--NVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC-EANP 1181
+P+ EC L + C +G C P C C +G L C + +
Sbjct: 984 VNYGIPAHRDIDECMLFGSEICKEGK-CVNTQPGYECYCKQGF---YYDGNLLECVDVDE 1039
Query: 1182 CLN-----GGTCRAAGGVSECICNARFSGQFCEVAKGLPLPLPFPLLEVAVPAAC 1231
CL+ G C G C C ++ + P + E PAAC
Sbjct: 1040 CLDESNCRNGVCENTRGGYRCACTP--PAEYSPAQRQCLSPEEMDVDECQDPAAC 1092
Score = 34.7 bits (78), Expect = 0.60
Identities = 20/72 (27%), Positives = 27/72 (37%), Gaps = 6/72 (8%)
Query: 805 CVSEDMCS-PDPCFNGGTCLVTWNDFHCTCPANFT-----GPTCAQQLWCPGQPCLPPAT 858
CV + C+ P C +GG C+ + C C + P C C P
Sbjct: 658 CVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGK 717
Query: 859 CEEVPDGFVCVA 870
CE P F C+A
Sbjct: 718 CENKPGSFKCIA 729
Score = 33.1 bits (74), Expect = 1.8
Identities = 16/39 (41%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Query: 366 PCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHT 404
PC++GG CS C CP + GR C V G G T
Sbjct: 116 PCMNGGQCSSRNQ---CLCPPDFTGRFCQVPAGGAGGGT 151
Score = 32.0 bits (71), Expect = 3.9
Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 3/30 (10%)
Query: 813 PDPCFNGGTCLVTWNDFHCTCPANFTGPTC 842
P PC NGG C + C CP +FTG C
Sbjct: 114 PLPCMNGGQCS---SRNQCLCPPDFTGRFC 140
Score = 30.8 bits (68), Expect = 8.7
Identities = 12/29 (41%), Positives = 16/29 (55%), Gaps = 3/29 (10%)
Query: 328 PCLNGGHCQDLPNGFQCHCPDGYAGPTCE 356
PC+NGG C + QC CP + G C+
Sbjct: 116 PCMNGGQCS---SRNQCLCPPDFTGRFCQ 141
>gi|18497288 latent transforming growth factor beta binding protein
3 isoform 2 [Homo sapiens]
Length = 1256
Score = 153 bits (387), Expect = 9e-37
Identities = 112/342 (32%), Positives = 154/342 (45%), Gaps = 61/342 (17%)
Query: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGP---RCELDIDECASRPCHHG-ATCRNLADRYE 131
C HG CVP PD + C+C PG++ R +D++EC + PC G C N Y
Sbjct: 585 CGHGE-CVPGPPD---YSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYN 640
Query: 132 CHCPLGY-----AGVTCEMEVDECASAP-CLHGGSCLDGVGSFRCVCAPGYG--GTR--- 180
CHC GY AG ++++ECA C GG C++ G ++C C PGY +R
Sbjct: 641 CHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPV 700
Query: 181 CQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGY--EGTHCEREVLECAS-APCEHNAS 237
C+ D+DEC+ G C + F+C GY +G R+V ECA +PC
Sbjct: 701 CE-DIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGW- 758
Query: 238 CLEGLGSFRCLCWPGYS----GELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFP 293
C GSFRC C GY+ G C +D DEC + G C P
Sbjct: 759 CENLPGSFRCTCAQGYAPAPDGRSC-LDVDECEAGDVCDNGICSNT-------------P 804
Query: 294 GAFSFRHAAGFLCHCPPGF----EGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDG 349
G+F C C G+ + + C ++DEC GG C + ++C CP G
Sbjct: 805 GSFQ--------CQCLSGYHLSRDRSHCE-DIDECDFPAACIGGDCINTNGSYRCLCPQG 855
Query: 350 Y---AGPTCEEDVDECLSDP--CLHGGTCSDTVAGYICRCPE 386
+ G C +D+DEC DP CL G C + Y+C C E
Sbjct: 856 HRLVGGRKC-QDIDECSQDPSLCLPHGACKNLQGSYVCVCDE 896
Score = 123 bits (308), Expect = 1e-27
Identities = 127/470 (27%), Positives = 171/470 (36%), Gaps = 97/470 (20%)
Query: 42 CASDPCAPGTECQATESGGYTC---------------GPMEPRGCA-TQPCHHGALCVPQ 85
C ++PC PG G Y C ++ CA C G C+
Sbjct: 620 CEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCI-- 677
Query: 86 GPDPTGFRCYCVPGF-----QGPRCELDIDECASRPCHHGATCRNLADRYEC-HCPLGY- 138
P ++C C PG+ + P CE DIDEC C N ++C C GY
Sbjct: 678 -NFPGHYKCNCYPGYRLKASRPPVCE-DIDECRDPSSCPDGKCENKPGSFKCIACQPGYR 735
Query: 139 --AGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYG----GTRCQLDLDECQSQP 192
G C +V+ECA G C + GSFRC CA GY G C LD+DEC++
Sbjct: 736 SQGGGACR-DVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSC-LDVDECEAGD 793
Query: 193 CAHGGTCHDLVNGFRCDCAGTGY----EGTHCEREVLECASAPCEHNASCLEGLGSFRCL 248
G C + F+C C +GY + +HCE ++ EC C+ GS+RCL
Sbjct: 794 VCDNGICSNTPGSFQCQCL-SGYHLSRDRSHCE-DIDECDFPAACIGGDCINTNGSYRCL 851
Query: 249 CWPGY---SGELCEVDEDECASSP--CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAG 303
C G+ G C+ D DEC+ P C G C L G F+
Sbjct: 852 CPQGHRLVGGRKCQ-DIDECSQDPSLCLPHGACKN-----LQGSYVCVCDEGFTPTQDQH 905
Query: 304 FLCHCPPGFEGADCGVEVDE-----------------CASRPCLNGGHCQDLP------N 340
+C + D+ C S G HC+ P
Sbjct: 906 GCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSA 965
Query: 341 GFQCHCPDGYA----------GPTCEEDVDECL---SDPCLHGGTCSDTVAGYICRCPET 387
F CPDG G D+DEC+ S+ C G C +T GY C C +
Sbjct: 966 EFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKE-GKCVNTQPGYECYCKQG 1024
Query: 388 W---GGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHC-PPGTHGP 433
+ G V + C + C E+ Y C C PP + P
Sbjct: 1025 FYYDGNLLECVDVDECLDESNCRNGVC----ENTRGGYRCACTPPAEYSP 1070
Score = 118 bits (295), Expect = 4e-26
Identities = 96/311 (30%), Positives = 133/311 (42%), Gaps = 56/311 (18%)
Query: 146 EVDECASAPCLHG-GSCLDGVGSFRCVCAPGYGGT---RCQLDLDECQSQPCAHG-GTCH 200
E DEC + G G C+ G + C C PGY R +D++EC+++PC G G C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 201 DLVNGFRCDCAGTGYE------GTHCEREVLECASAP-CEHNASCLEGLGSFRCLCWPGY 253
+ + C C GY G C ++ ECA C C+ G ++C C+PGY
Sbjct: 634 NTGGSYNCHC-NRGYRLHVGAGGRSCV-DLNECAKPHLCGDGGFCINFPGHYKCNCYPGY 691
Query: 254 SGE-----LCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHC 308
+ +CE D DEC G+C + PG+F C
Sbjct: 692 RLKASRPPVCE-DIDECRDPSSCPDGKCENK-------------PGSFK-------CIAC 730
Query: 309 PPGFEGADCGV--EVDECASRPCLNGGHCQDLPNGFQCHCPDGYA----GPTCEEDVDEC 362
PG+ G +V+ECA + G C++LP F+C C GYA G +C DVDEC
Sbjct: 731 QPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSC-LDVDEC 789
Query: 363 LSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQG-HTCPLAATCIP---IFESG 418
+ G CS+T + C+C G S + C+ C A CI I +G
Sbjct: 790 EAGDVCDNGICSNTPGSFQCQC---LSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNG 846
Query: 419 VHSYVCHCPPG 429
SY C CP G
Sbjct: 847 --SYRCLCPQG 855
Score = 113 bits (283), Expect = 1e-24
Identities = 111/380 (29%), Positives = 148/380 (38%), Gaps = 61/380 (16%)
Query: 39 PSACASDPCA--PGT-ECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPD--PTGFR 93
PS+C C PG+ +C A + G + G R C G+ C P + P FR
Sbjct: 710 PSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRD--VNECAEGSPCSPGWCENLPGSFR 767
Query: 94 CYCVPGF----QGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYA----GVTCEM 145
C C G+ G C LD+DEC + C N ++C C GY CE
Sbjct: 768 CTCAQGYAPAPDGRSC-LDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCE- 825
Query: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGY---GGTRCQLDLDECQSQP--CAHGGTCH 200
++DEC GG C++ GS+RC+C G+ GG +CQ D+DEC P C G C
Sbjct: 826 DIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQ-DIDECSQDPSLCLPHGACK 884
Query: 201 DLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEV 260
+L + C C G+ T + E H C C S V
Sbjct: 885 NLQGSYVCVC-DEGFTPTQDQHGCEEVEQP--HHKKECYLNFDD-TVFC---DSVLATNV 937
Query: 261 DEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPG--------- 311
+ EC C G A +G +P +A F CP G
Sbjct: 938 TQQECC---CSLG---------AGWGDHCEIYP--CPVYSSAEFHSLCPDGKGYTQDNNI 983
Query: 312 -FEGADCGVEVDEC---ASRPCLNGGHCQDLPNGFQCHCPDG--YAGPTCE-EDVDECLS 364
G ++DEC S C G C + G++C+C G Y G E DVDECL
Sbjct: 984 VNYGIPAHRDIDECMLFGSEIC-KEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLD 1042
Query: 365 DPCLHGGTCSDTVAGYICRC 384
+ G C +T GY C C
Sbjct: 1043 ESNCRNGVCENTRGGYRCAC 1062
Score = 81.6 bits (200), Expect = 4e-15
Identities = 89/355 (25%), Positives = 124/355 (34%), Gaps = 64/355 (18%)
Query: 134 CPLGYAGVTCE--MEVDECASAPCLHGGSCLDGVGSFRCVCAPGY----GGTRCQLDLDE 187
CP GY + +++ECA G CL+ GS+RCVC PG+ T+C D E
Sbjct: 341 CPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPE 400
Query: 188 CQS---------QPCAHGGT--------CHDLVNGFRCDCAGTGYEGTHCEREVLECASA 230
+S C H T C + + C +GT +E+
Sbjct: 401 EKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKG 460
Query: 231 ---PCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQ--------------HG 273
H ++G F P + ++ E + P +
Sbjct: 461 YHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSE 520
Query: 274 GRCLQRSDPALYGGVQAAFPGAFSFRH---AAGFLCHCPPGFEGADCG----VEVDECAS 326
R +Q+S P +P S FL PP + E DEC
Sbjct: 521 ERSVQQSHPTATTTPARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRL 580
Query: 327 RPCLNG-GHCQDLPNGFQCHCPDGYAGPTCEE---DVDECLSDPCLHG-GTCSDTVAGYI 381
+ G G C P + CHC GY DV+EC ++PC G G C +T Y
Sbjct: 581 NQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYN 640
Query: 382 CRCPETW------GGRDCSVQLTGC-QGHTCPLAATCIPIFESGVHSYVCHCPPG 429
C C + GGR C V L C + H C CI + Y C+C PG
Sbjct: 641 CHCNRGYRLHVGAGGRSC-VDLNECAKPHLCGDGGFCI----NFPGHYKCNCYPG 690
Score = 67.4 bits (163), Expect = 8e-11
Identities = 57/183 (31%), Positives = 80/183 (43%), Gaps = 18/183 (9%)
Query: 1035 PGAREHFASWPGTPAPILG-CRGAPVCAP-SPCLHDGACRDLFDAFACACGPGW----EG 1088
PG+ + A PG + G CR CA SPC G C +L +F C C G+ +G
Sbjct: 722 PGSFKCIACQPGYRSQGGGACRDVNECAEGSPC-SPGWCENLPGSFRCTCAQGYAPAPDG 780
Query: 1089 PRCEAHVDPCHSAP-CARGRCHTHPDGRFECRCPPGFGGPRCRLPVPS-KECSLNVTCLD 1146
C VD C + C G C P G F+C+C G+ R R EC C+
Sbjct: 781 RSC-LDVDECEAGDVCDNGICSNTP-GSFQCQCLSGYHLSRDRSHCEDIDECDFPAACI- 837
Query: 1147 GSPCEGGSPAANCSCLEG---LAGQRCQVPTLPCEANP--CLNGGTCRAAGGVSECICNA 1201
G C + + C C +G + G++CQ C +P CL G C+ G C+C+
Sbjct: 838 GGDCINTNGSYRCLCPQGHRLVGGRKCQ-DIDECSQDPSLCLPHGACKNLQGSYVCVCDE 896
Query: 1202 RFS 1204
F+
Sbjct: 897 GFT 899
Score = 67.0 bits (162), Expect = 1e-10
Identities = 90/365 (24%), Positives = 126/365 (34%), Gaps = 90/365 (24%)
Query: 92 FRCYCVPGFQ---GPRCELDIDECASRPC---HHGATCRNLADRYECHCPLGYAGVT--- 142
+RC C G + G +C+ DIDEC+ P HGA C+NL Y C C G+
Sbjct: 848 YRCLCPQGHRLVGGRKCQ-DIDECSQDPSLCLPHGA-CKNLQGSYVCVCDEGFTPTQDQH 905
Query: 143 -------------CEMEVDE-----------------CASAPCLHGGSC------LDGVG 166
C + D+ C S G C +
Sbjct: 906 GCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSA 965
Query: 167 SFRCVCAPGYGGTR----------CQLDLDECQ---SQPCAHGGTCHDLVNGFRCDCAGT 213
F +C G G T+ D+DEC S+ C G C + G+ C C
Sbjct: 966 EFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEG-KCVNTQPGYECYCK-- 1022
Query: 214 GYEGTHCEREVLECASAP-CEHNASCLEGL-----GSFRCLCWPGYSGELCE---VDEDE 264
+G + + +LEC C ++C G+ G +RC C P + + +E
Sbjct: 1023 --QGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEE 1080
Query: 265 CASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDEC 324
+P + QR + + G A A +F C C +G G + C
Sbjct: 1081 MERAPERRDVCWSQRGEDGMCAGPLAG--PALTFDD-----CCCR---QGRGWGAQCRPC 1130
Query: 325 ASRPCLNGGHC---QDLPNGFQCHCPDGYAGPTCEEDVDECLSDPC-LHGGTCSDTVAGY 380
R G HC Q N F P P +ED E SD C G C G
Sbjct: 1131 PPRGA--GSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGA 1188
Query: 381 ICRCP 385
+C CP
Sbjct: 1189 VCECP 1193
Score = 59.3 bits (142), Expect = 2e-08
Identities = 85/358 (23%), Positives = 121/358 (33%), Gaps = 53/358 (14%)
Query: 42 CASDP--CAPGTECQATESGGYTC-------GPMEPRGC--ATQPCHHGALCVPQGPDPT 90
C+ DP C P C+ + G Y C + GC QP HH C D
Sbjct: 870 CSQDPSLCLPHGACKNLQ-GSYVCVCDEGFTPTQDQHGCEEVEQP-HHKKECYLNFDDTV 927
Query: 91 GFRCYCVPGFQGPRCELDI-----DECASRPCHHGATCRNLADRYECHCPLGYA------ 139
C + D C PC ++ + CP G
Sbjct: 928 FCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAE-----FHSLCPDGKGYTQDNN 982
Query: 140 ----GVTCEMEVDECA--SAPCLHGGSCLDGVGSFRCVCAPG--YGGTRCQ-LDLDECQS 190
G+ ++DEC + G C++ + C C G Y G + +D+DEC
Sbjct: 983 IVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLD 1042
Query: 191 QPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVL---ECASAPCEHNASCLEGLGSFRC 247
+ G C + G+RC C E + +R+ L E AP E C G
Sbjct: 1043 ESNCRNGVCENTRGGYRCACTPPA-EYSPAQRQCLSPEEMERAP-ERRDVCWSQRGE-DG 1099
Query: 248 LCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCH 307
+C +G D D C G +C + + SF + L
Sbjct: 1100 MCAGPLAGPALTFD-DCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLG 1158
Query: 308 CPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGY---AGPTCEEDVDEC 362
PP E + + DEC C++ G C P G C CP G+ A D+DEC
Sbjct: 1159 KPPRDEDSS-EEDSDECR---CVS-GRCVPRPGGAVCECPGGFQLDASRARCVDIDEC 1211
Score = 43.1 bits (100), Expect = 0.002
Identities = 42/159 (26%), Positives = 58/159 (36%), Gaps = 15/159 (9%)
Query: 1054 CRGAPVCAPSPCLHD-GACRDLFDAFACACGPGWE-----GPRCEAHVDPCHSAP-CARG 1106
C C PC G C + ++ C C G+ G R ++ C C G
Sbjct: 614 CVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDG 673
Query: 1107 RCHTHPDGRFECRCPPGFGGPRCRLPV--PSKECSLNVTCLDGSPCEGGSPAANC-SCLE 1163
+ G ++C C PG+ R PV EC +C DG CE + C +C
Sbjct: 674 GFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGK-CENKPGSFKCIACQP 732
Query: 1164 GL---AGQRCQVPTLPCEANPCLNGGTCRAAGGVSECIC 1199
G G C+ E +PC + G C G C C
Sbjct: 733 GYRSQGGGACRDVNECAEGSPC-SPGWCENLPGSFRCTC 770
Score = 42.0 bits (97), Expect = 0.004
Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 12/86 (13%)
Query: 1132 PVPSKECSLNVTCLDGSPCEGGSPAA----NCSCLEGLAGQRCQVPTLPCEANPCLNGGT 1187
PV K L C D C+ GS N + L G +V P PC+NGG
Sbjct: 68 PVICKRTCLKGQCRDS--CQQGSNMTLIGENGHSTDTLTGSGFRVVVCPL---PCMNGGQ 122
Query: 1188 CRAAGGVSECICNARFSGQFCEVAKG 1213
C + ++C+C F+G+FC+V G
Sbjct: 123 CSSR---NQCLCPPDFTGRFCQVPAG 145
Score = 40.8 bits (94), Expect = 0.008
Identities = 56/237 (23%), Positives = 79/237 (33%), Gaps = 37/237 (15%)
Query: 40 SACASDPCAPGTECQATESGGYTCGPM-EPRGCAT-QPCHHGALCVPQGPDPTGFRCYCV 97
S A P AP + A++ Y + +P G P H A VP GP
Sbjct: 165 STGALPPLAPEGDSVASKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAP 224
Query: 98 PGFQG------PRCELDIDECASRPCHHGATCRNLAD-------RYECHCPLGYAGVTCE 144
P P + + S A ++L R PLG
Sbjct: 225 PPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLG------R 278
Query: 145 MEVDECASAPCLHGGSCLDGVGSFRCVCAP---GYGGTRC----QLDLDECQSQPCAHGG 197
D PC G + L G+ C +G ++C QL Q G
Sbjct: 279 CFQDTLPKQPC--GSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGE 336
Query: 198 TCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYS 254
D G++ THC+ ++ ECA + CL GS+RC+C PG+S
Sbjct: 337 VGADCPQGYK------RLNSTHCQ-DINECAMPGVCRHGDCLNNPGSYRCVCPPGHS 386
Score = 40.4 bits (93), Expect = 0.011
Identities = 25/68 (36%), Positives = 26/68 (38%), Gaps = 4/68 (5%)
Query: 1137 ECSLNVTCLDGSPCEGGSPAANCSCLEGLAG---QRCQVPTLPCEANPCLNG-GTCRAAG 1192
EC LN C G P +C C G R V CEA PC G G C G
Sbjct: 577 ECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTG 636
Query: 1193 GVSECICN 1200
G C CN
Sbjct: 637 GSYNCHCN 644
Score = 38.9 bits (89), Expect = 0.032
Identities = 43/162 (26%), Positives = 57/162 (35%), Gaps = 23/162 (14%)
Query: 262 EDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCG--V 319
ED C S G + Y GVQ P R G CP G++ +
Sbjct: 301 EDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGP----VRGEVG--ADCPQGYKRLNSTHCQ 354
Query: 320 EVDECASRPCLNGGHCQDLPNGFQCHCPDGYA-GPT---CEEDVDE----CL-----SDP 366
+++ECA G C + P ++C CP G++ GP+ C D E C
Sbjct: 355 DINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQ 414
Query: 367 CLHGGTCSDTVAGYICRCPETWGGR--DCSVQLTGCQGHTCP 406
C H T T C + WG R C T CP
Sbjct: 415 CQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICP 456
Score = 38.9 bits (89), Expect = 0.032
Identities = 22/75 (29%), Positives = 28/75 (37%), Gaps = 5/75 (6%)
Query: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT---GPTCAQQLWCPGQP--CLPPATC 859
C D C GG C+ T + C CP G C C P CLP C
Sbjct: 824 CEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGAC 883
Query: 860 EEVPDGFVCVAEATF 874
+ + +VCV + F
Sbjct: 884 KNLQGSYVCVCDEGF 898
Score = 37.7 bits (86), Expect = 0.071
Identities = 63/247 (25%), Positives = 80/247 (32%), Gaps = 77/247 (31%)
Query: 76 CHHGALCVPQGPDPTGFRCYCVPGF--QGPRCE-LDIDECASRPCHHGATCRNLADRYEC 132
C G CV P G+ CYC GF G E +D+DEC C N Y C
Sbjct: 1005 CKEGK-CVNTQP---GYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRC 1060
Query: 133 HC--PLGYAGVT--C----EMEV-----DECAS-------------APCLHGGSCL---- 162
C P Y+ C EME D C S P L C
Sbjct: 1061 ACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQG 1120
Query: 163 DGVGSFRCVCAPGYGGTRC----------------------------QLDLDECQSQPCA 194
G G+ C P G+ C + D DEC+ C
Sbjct: 1121 RGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR---CV 1177
Query: 195 HGGTCHDLVNGFRCDCAGTGYEGTHCER--EVLECASAP-----CEHNASCLEGLGSFRC 247
G C G C+C G R ++ EC C+ + C+ GSFRC
Sbjct: 1178 -SGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCK-SERCVNTSGSFRC 1235
Query: 248 LCWPGYS 254
+C G++
Sbjct: 1236 VCKAGFA 1242
Score = 36.6 bits (83), Expect = 0.16
Identities = 41/159 (25%), Positives = 54/159 (33%), Gaps = 30/159 (18%)
Query: 35 PSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGF-- 92
P P+ D C C+ G C P PRG G+ C + F
Sbjct: 1104 PLAGPALTFDDCC-----CRQGRGWGAQCRPCPPRGA-------GSHCPTSQSESNSFWD 1151
Query: 93 ---RCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGY----AGVTCEM 145
P E D DEC C G C C CP G+ + C +
Sbjct: 1152 TSPLLLGKPPRDEDSSEEDSDECR---CVSGR-CVPRPGGAVCECPGGFQLDASRARC-V 1206
Query: 146 EVDECASAP----CLHGGSCLDGVGSFRCVCAPGYGGTR 180
++DEC C++ GSFRCVC G+ +R
Sbjct: 1207 DIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSR 1245
Score = 34.7 bits (78), Expect = 0.60
Identities = 20/72 (27%), Positives = 27/72 (37%), Gaps = 6/72 (8%)
Query: 805 CVSEDMCS-PDPCFNGGTCLVTWNDFHCTCPANFT-----GPTCAQQLWCPGQPCLPPAT 858
CV + C+ P C +GG C+ + C C + P C C P
Sbjct: 658 CVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGK 717
Query: 859 CEEVPDGFVCVA 870
CE P F C+A
Sbjct: 718 CENKPGSFKCIA 729
Score = 34.7 bits (78), Expect = 0.60
Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 6/56 (10%)
Query: 1054 CRGAPVCA--PSPCLHDGACRDLFDAFACACGPGWEGPR----CEAHVDPCHSAPC 1103
C+ C+ PS CL GAC++L ++ C C G+ + CE P H C
Sbjct: 864 CQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKEC 919
Score = 33.1 bits (74), Expect = 1.8
Identities = 16/39 (41%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Query: 366 PCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHT 404
PC++GG CS C CP + GR C V G G T
Sbjct: 116 PCMNGGQCSSRNQ---CLCPPDFTGRFCQVPAGGAGGGT 151
Score = 32.0 bits (71), Expect = 3.9
Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 3/30 (10%)
Query: 813 PDPCFNGGTCLVTWNDFHCTCPANFTGPTC 842
P PC NGG C + C CP +FTG C
Sbjct: 114 PLPCMNGGQCS---SRNQCLCPPDFTGRFC 140
Score = 30.8 bits (68), Expect = 8.7
Identities = 12/29 (41%), Positives = 16/29 (55%), Gaps = 3/29 (10%)
Query: 328 PCLNGGHCQDLPNGFQCHCPDGYAGPTCE 356
PC+NGG C + QC CP + G C+
Sbjct: 116 PCMNGGQCS---SRNQCLCPPDFTGRFCQ 141
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.140 0.483
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,783,472
Number of Sequences: 37866
Number of extensions: 4084326
Number of successful extensions: 26968
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 198
Number of HSP's successfully gapped in prelim test: 317
Number of HSP's that attempted gapping in prelim test: 10296
Number of HSP's gapped (non-prelim): 7121
length of query: 1285
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1171
effective length of database: 13,930,794
effective search space: 16312959774
effective search space used: 16312959774
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.