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Search of human proteins with 112382233
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|112382233 mucin 4 isoform d [Homo sapiens]
(1176 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|112382233 mucin 4 isoform d [Homo sapiens] 2485 0.0
gi|167736355 mucin 4 isoform a [Homo sapiens] 2427 0.0
gi|112382231 mucin 4 isoform e [Homo sapiens] 2361 0.0
gi|10092665 sushi domain containing 2 [Homo sapiens] 140 5e-33
gi|115298674 nidogen 1 precursor [Homo sapiens] 71 5e-12
gi|144953895 nidogen 2 precursor [Homo sapiens] 69 3e-11
gi|134268640 tectorin alpha precursor [Homo sapiens] 59 3e-08
gi|122937283 6720455I24Rik homolog [Homo sapiens] 58 6e-08
gi|24041035 notch 2 preproprotein [Homo sapiens] 55 3e-07
gi|55770876 notch4 preproprotein [Homo sapiens] 54 1e-06
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 53 1e-06
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] 53 2e-06
gi|126091152 cubilin [Homo sapiens] 52 3e-06
gi|61743978 stabilin 1 precursor [Homo sapiens] 51 6e-06
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 50 1e-05
gi|11321571 slit homolog 3 [Homo sapiens] 50 2e-05
gi|134031945 SCO-spondin [Homo sapiens] 50 2e-05
gi|110735443 delta-like 1 [Homo sapiens] 48 6e-05
gi|148833508 notch1 preproprotein [Homo sapiens] 46 2e-04
gi|126012562 low density lipoprotein-related protein 1 [Homo sap... 46 2e-04
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 46 2e-04
gi|4557679 jagged 1 precursor [Homo sapiens] 46 2e-04
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 46 2e-04
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 46 2e-04
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 46 2e-04
gi|161019170 mucin 5AC [Homo sapiens] 45 3e-04
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr... 45 3e-04
gi|62988324 tenascin N [Homo sapiens] 45 4e-04
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 45 5e-04
gi|239757284 PREDICTED: similar to Fc fragment of IgG binding pr... 45 5e-04
>gi|112382233 mucin 4 isoform d [Homo sapiens]
Length = 1176
Score = 2485 bits (6441), Expect = 0.0
Identities = 1176/1176 (100%), Positives = 1176/1176 (100%)
Query: 1 MKGARWRRVPWVSLSCLCLCLLPHVVPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPS 60
MKGARWRRVPWVSLSCLCLCLLPHVVPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPS
Sbjct: 1 MKGARWRRVPWVSLSCLCLCLLPHVVPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPS 60
Query: 61 TAMHTRSTAAPIPILPERGVSLFPYGAGAGDLEFVRRTVDFTSPLFKPATGFPLGSSLRD 120
TAMHTRSTAAPIPILPERGVSLFPYGAGAGDLEFVRRTVDFTSPLFKPATGFPLGSSLRD
Sbjct: 61 TAMHTRSTAAPIPILPERGVSLFPYGAGAGDLEFVRRTVDFTSPLFKPATGFPLGSSLRD 120
Query: 121 SLYFTDNGQIIFPESDYQIFSYPNPLPTGFTGRDPVALVAPFWDDADFSTGRGTTFYQEY 180
SLYFTDNGQIIFPESDYQIFSYPNPLPTGFTGRDPVALVAPFWDDADFSTGRGTTFYQEY
Sbjct: 121 SLYFTDNGQIIFPESDYQIFSYPNPLPTGFTGRDPVALVAPFWDDADFSTGRGTTFYQEY 180
Query: 181 ETFYGEHSLLVQQAESWIRKMTNNGGYKARWALKVTWVNAHAYPAQWTLGSNTYQAILST 240
ETFYGEHSLLVQQAESWIRKMTNNGGYKARWALKVTWVNAHAYPAQWTLGSNTYQAILST
Sbjct: 181 ETFYGEHSLLVQQAESWIRKMTNNGGYKARWALKVTWVNAHAYPAQWTLGSNTYQAILST 240
Query: 241 DGSRSYALFLYQSGGMQWDVAQRSGNPVLMGFSSGDGYFENSPLMSQPVWERYRPDRFLN 300
DGSRSYALFLYQSGGMQWDVAQRSGNPVLMGFSSGDGYFENSPLMSQPVWERYRPDRFLN
Sbjct: 241 DGSRSYALFLYQSGGMQWDVAQRSGNPVLMGFSSGDGYFENSPLMSQPVWERYRPDRFLN 300
Query: 301 SNSGLQGLQFYRLHREERPNYRLECLQWLKSQPRWPSWGWNQVSCPCSWQQGRRDLRFQP 360
SNSGLQGLQFYRLHREERPNYRLECLQWLKSQPRWPSWGWNQVSCPCSWQQGRRDLRFQP
Sbjct: 301 SNSGLQGLQFYRLHREERPNYRLECLQWLKSQPRWPSWGWNQVSCPCSWQQGRRDLRFQP 360
Query: 361 VSIGRWGLGSRQLCSFTSWRGGVCCSYGPWGEFREGWHVQRPWQLAQELEPQSWCCRWND 420
VSIGRWGLGSRQLCSFTSWRGGVCCSYGPWGEFREGWHVQRPWQLAQELEPQSWCCRWND
Sbjct: 361 VSIGRWGLGSRQLCSFTSWRGGVCCSYGPWGEFREGWHVQRPWQLAQELEPQSWCCRWND 420
Query: 421 KPYLCALYQQRRPHVGCATYRPPQPAWMFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNS 480
KPYLCALYQQRRPHVGCATYRPPQPAWMFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNS
Sbjct: 421 KPYLCALYQQRRPHVGCATYRPPQPAWMFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNS 480
Query: 481 SFLLQGRTAQTGSAQATNFIAFAAQYRSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPD 540
SFLLQGRTAQTGSAQATNFIAFAAQYRSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPD
Sbjct: 481 SFLLQGRTAQTGSAQATNFIAFAAQYRSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPD 540
Query: 541 HEDGGGQETFNATGVLLSRNGSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGL 600
HEDGGGQETFNATGVLLSRNGSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGL
Sbjct: 541 HEDGGGQETFNATGVLLSRNGSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGL 600
Query: 601 LGVWNNNPEDDFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVFY 660
LGVWNNNPEDDFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVFY
Sbjct: 601 LGVWNNNPEDDFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVFY 660
Query: 661 SQLQKNSSWAEHLISNCDGDSSCIYDTLALRNASIGLHTREVSKNYEQANATLNQYPPSI 720
SQLQKNSSWAEHLISNCDGDSSCIYDTLALRNASIGLHTREVSKNYEQANATLNQYPPSI
Sbjct: 661 SQLQKNSSWAEHLISNCDGDSSCIYDTLALRNASIGLHTREVSKNYEQANATLNQYPPSI 720
Query: 721 NGGRVIEAYKGQTTLIQYTSNAEDANFTLRDSCTDLELFENGTLLWTPKSLEPFTLEILA 780
NGGRVIEAYKGQTTLIQYTSNAEDANFTLRDSCTDLELFENGTLLWTPKSLEPFTLEILA
Sbjct: 721 NGGRVIEAYKGQTTLIQYTSNAEDANFTLRDSCTDLELFENGTLLWTPKSLEPFTLEILA 780
Query: 781 RSAKIGLASALQPRTVVCHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSED 840
RSAKIGLASALQPRTVVCHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSED
Sbjct: 781 RSAKIGLASALQPRTVVCHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSED 840
Query: 841 ACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYIS 900
ACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYIS
Sbjct: 841 ACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYIS 900
Query: 901 QTLGCQPMCTCPPAFTDSRCFLAGNNFSPTVNLELPLRVIQLLLSEEENASMAEVNASVA 960
QTLGCQPMCTCPPAFTDSRCFLAGNNFSPTVNLELPLRVIQLLLSEEENASMAEVNASVA
Sbjct: 901 QTLGCQPMCTCPPAFTDSRCFLAGNNFSPTVNLELPLRVIQLLLSEEENASMAEVNASVA 960
Query: 961 YRLGTLDMRAFLRNSQVERIDSAAPASGSPIQHWMVISEFQYRPRGPVIDFLNNQLLAAV 1020
YRLGTLDMRAFLRNSQVERIDSAAPASGSPIQHWMVISEFQYRPRGPVIDFLNNQLLAAV
Sbjct: 961 YRLGTLDMRAFLRNSQVERIDSAAPASGSPIQHWMVISEFQYRPRGPVIDFLNNQLLAAV 1020
Query: 1021 VEAFLYHVPRRSEEPRNDVVFQPISGEDVRDVTALNVSTLKAYFRCDGYKGYDLVYSPQS 1080
VEAFLYHVPRRSEEPRNDVVFQPISGEDVRDVTALNVSTLKAYFRCDGYKGYDLVYSPQS
Sbjct: 1021 VEAFLYHVPRRSEEPRNDVVFQPISGEDVRDVTALNVSTLKAYFRCDGYKGYDLVYSPQS 1080
Query: 1081 GFTCVSPCSRGYCDHGGQCQHLPSGPRCSCVSFSIYTAWGEHCEHLSMKLDAFFGIFFGA 1140
GFTCVSPCSRGYCDHGGQCQHLPSGPRCSCVSFSIYTAWGEHCEHLSMKLDAFFGIFFGA
Sbjct: 1081 GFTCVSPCSRGYCDHGGQCQHLPSGPRCSCVSFSIYTAWGEHCEHLSMKLDAFFGIFFGA 1140
Query: 1141 LGGLLLLGVGTFVVLRFWGCSGARFSYFLNSAEALP 1176
LGGLLLLGVGTFVVLRFWGCSGARFSYFLNSAEALP
Sbjct: 1141 LGGLLLLGVGTFVVLRFWGCSGARFSYFLNSAEALP 1176
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 2427 bits (6291), Expect = 0.0
Identities = 1150/1150 (100%), Positives = 1150/1150 (100%)
Query: 27 PGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPSTAMHTRSTAAPIPILPERGVSLFPYG 86
PGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPSTAMHTRSTAAPIPILPERGVSLFPYG
Sbjct: 4135 PGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPSTAMHTRSTAAPIPILPERGVSLFPYG 4194
Query: 87 AGAGDLEFVRRTVDFTSPLFKPATGFPLGSSLRDSLYFTDNGQIIFPESDYQIFSYPNPL 146
AGAGDLEFVRRTVDFTSPLFKPATGFPLGSSLRDSLYFTDNGQIIFPESDYQIFSYPNPL
Sbjct: 4195 AGAGDLEFVRRTVDFTSPLFKPATGFPLGSSLRDSLYFTDNGQIIFPESDYQIFSYPNPL 4254
Query: 147 PTGFTGRDPVALVAPFWDDADFSTGRGTTFYQEYETFYGEHSLLVQQAESWIRKMTNNGG 206
PTGFTGRDPVALVAPFWDDADFSTGRGTTFYQEYETFYGEHSLLVQQAESWIRKMTNNGG
Sbjct: 4255 PTGFTGRDPVALVAPFWDDADFSTGRGTTFYQEYETFYGEHSLLVQQAESWIRKMTNNGG 4314
Query: 207 YKARWALKVTWVNAHAYPAQWTLGSNTYQAILSTDGSRSYALFLYQSGGMQWDVAQRSGN 266
YKARWALKVTWVNAHAYPAQWTLGSNTYQAILSTDGSRSYALFLYQSGGMQWDVAQRSGN
Sbjct: 4315 YKARWALKVTWVNAHAYPAQWTLGSNTYQAILSTDGSRSYALFLYQSGGMQWDVAQRSGN 4374
Query: 267 PVLMGFSSGDGYFENSPLMSQPVWERYRPDRFLNSNSGLQGLQFYRLHREERPNYRLECL 326
PVLMGFSSGDGYFENSPLMSQPVWERYRPDRFLNSNSGLQGLQFYRLHREERPNYRLECL
Sbjct: 4375 PVLMGFSSGDGYFENSPLMSQPVWERYRPDRFLNSNSGLQGLQFYRLHREERPNYRLECL 4434
Query: 327 QWLKSQPRWPSWGWNQVSCPCSWQQGRRDLRFQPVSIGRWGLGSRQLCSFTSWRGGVCCS 386
QWLKSQPRWPSWGWNQVSCPCSWQQGRRDLRFQPVSIGRWGLGSRQLCSFTSWRGGVCCS
Sbjct: 4435 QWLKSQPRWPSWGWNQVSCPCSWQQGRRDLRFQPVSIGRWGLGSRQLCSFTSWRGGVCCS 4494
Query: 387 YGPWGEFREGWHVQRPWQLAQELEPQSWCCRWNDKPYLCALYQQRRPHVGCATYRPPQPA 446
YGPWGEFREGWHVQRPWQLAQELEPQSWCCRWNDKPYLCALYQQRRPHVGCATYRPPQPA
Sbjct: 4495 YGPWGEFREGWHVQRPWQLAQELEPQSWCCRWNDKPYLCALYQQRRPHVGCATYRPPQPA 4554
Query: 447 WMFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQY 506
WMFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQY
Sbjct: 4555 WMFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQY 4614
Query: 507 RSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRNGSEVSA 566
RSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRNGSEVSA
Sbjct: 4615 RSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRNGSEVSA 4674
Query: 567 SFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIPPGSPE 626
SFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIPPGSPE
Sbjct: 4675 SFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIPPGSPE 4734
Query: 627 EMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVFYSQLQKNSSWAEHLISNCDGDSSCIYD 686
EMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVFYSQLQKNSSWAEHLISNCDGDSSCIYD
Sbjct: 4735 EMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVFYSQLQKNSSWAEHLISNCDGDSSCIYD 4794
Query: 687 TLALRNASIGLHTREVSKNYEQANATLNQYPPSINGGRVIEAYKGQTTLIQYTSNAEDAN 746
TLALRNASIGLHTREVSKNYEQANATLNQYPPSINGGRVIEAYKGQTTLIQYTSNAEDAN
Sbjct: 4795 TLALRNASIGLHTREVSKNYEQANATLNQYPPSINGGRVIEAYKGQTTLIQYTSNAEDAN 4854
Query: 747 FTLRDSCTDLELFENGTLLWTPKSLEPFTLEILARSAKIGLASALQPRTVVCHCNAESQC 806
FTLRDSCTDLELFENGTLLWTPKSLEPFTLEILARSAKIGLASALQPRTVVCHCNAESQC
Sbjct: 4855 FTLRDSCTDLELFENGTLLWTPKSLEPFTLEILARSAKIGLASALQPRTVVCHCNAESQC 4914
Query: 807 LYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKGCEACPPNLT 866
LYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKGCEACPPNLT
Sbjct: 4915 LYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKGCEACPPNLT 4974
Query: 867 GDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRCFLAGNN 926
GDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRCFLAGNN
Sbjct: 4975 GDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRCFLAGNN 5034
Query: 927 FSPTVNLELPLRVIQLLLSEEENASMAEVNASVAYRLGTLDMRAFLRNSQVERIDSAAPA 986
FSPTVNLELPLRVIQLLLSEEENASMAEVNASVAYRLGTLDMRAFLRNSQVERIDSAAPA
Sbjct: 5035 FSPTVNLELPLRVIQLLLSEEENASMAEVNASVAYRLGTLDMRAFLRNSQVERIDSAAPA 5094
Query: 987 SGSPIQHWMVISEFQYRPRGPVIDFLNNQLLAAVVEAFLYHVPRRSEEPRNDVVFQPISG 1046
SGSPIQHWMVISEFQYRPRGPVIDFLNNQLLAAVVEAFLYHVPRRSEEPRNDVVFQPISG
Sbjct: 5095 SGSPIQHWMVISEFQYRPRGPVIDFLNNQLLAAVVEAFLYHVPRRSEEPRNDVVFQPISG 5154
Query: 1047 EDVRDVTALNVSTLKAYFRCDGYKGYDLVYSPQSGFTCVSPCSRGYCDHGGQCQHLPSGP 1106
EDVRDVTALNVSTLKAYFRCDGYKGYDLVYSPQSGFTCVSPCSRGYCDHGGQCQHLPSGP
Sbjct: 5155 EDVRDVTALNVSTLKAYFRCDGYKGYDLVYSPQSGFTCVSPCSRGYCDHGGQCQHLPSGP 5214
Query: 1107 RCSCVSFSIYTAWGEHCEHLSMKLDAFFGIFFGALGGLLLLGVGTFVVLRFWGCSGARFS 1166
RCSCVSFSIYTAWGEHCEHLSMKLDAFFGIFFGALGGLLLLGVGTFVVLRFWGCSGARFS
Sbjct: 5215 RCSCVSFSIYTAWGEHCEHLSMKLDAFFGIFFGALGGLLLLGVGTFVVLRFWGCSGARFS 5274
Query: 1167 YFLNSAEALP 1176
YFLNSAEALP
Sbjct: 5275 YFLNSAEALP 5284
Score = 77.8 bits (190), Expect = 6e-14
Identities = 41/68 (60%), Positives = 46/68 (67%), Gaps = 2/68 (2%)
Query: 1 MKGARWRRVPWVSLSCLCLCLLPHVVPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPS 60
MKGARWRRVPWVSLSCLCLCLLPHVVPG T +L T G +TA T S T S
Sbjct: 1 MKGARWRRVPWVSLSCLCLCLLPHVVPGTTEDTLIT--GSKTAAPVTSTGSTTATLEGQS 58
Query: 61 TAMHTRST 68
TA +R++
Sbjct: 59 TAASSRTS 66
>gi|112382231 mucin 4 isoform e [Homo sapiens]
Length = 1125
Score = 2361 bits (6118), Expect = 0.0
Identities = 1125/1176 (95%), Positives = 1125/1176 (95%), Gaps = 51/1176 (4%)
Query: 1 MKGARWRRVPWVSLSCLCLCLLPHVVPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPS 60
MKGARWRRVPWVSLSCLCLCLLPHVVP
Sbjct: 1 MKGARWRRVPWVSLSCLCLCLLPHVVP--------------------------------- 27
Query: 61 TAMHTRSTAAPIPILPERGVSLFPYGAGAGDLEFVRRTVDFTSPLFKPATGFPLGSSLRD 120
GVSLFPYGAGAGDLEFVRRTVDFTSPLFKPATGFPLGSSLRD
Sbjct: 28 ------------------GVSLFPYGAGAGDLEFVRRTVDFTSPLFKPATGFPLGSSLRD 69
Query: 121 SLYFTDNGQIIFPESDYQIFSYPNPLPTGFTGRDPVALVAPFWDDADFSTGRGTTFYQEY 180
SLYFTDNGQIIFPESDYQIFSYPNPLPTGFTGRDPVALVAPFWDDADFSTGRGTTFYQEY
Sbjct: 70 SLYFTDNGQIIFPESDYQIFSYPNPLPTGFTGRDPVALVAPFWDDADFSTGRGTTFYQEY 129
Query: 181 ETFYGEHSLLVQQAESWIRKMTNNGGYKARWALKVTWVNAHAYPAQWTLGSNTYQAILST 240
ETFYGEHSLLVQQAESWIRKMTNNGGYKARWALKVTWVNAHAYPAQWTLGSNTYQAILST
Sbjct: 130 ETFYGEHSLLVQQAESWIRKMTNNGGYKARWALKVTWVNAHAYPAQWTLGSNTYQAILST 189
Query: 241 DGSRSYALFLYQSGGMQWDVAQRSGNPVLMGFSSGDGYFENSPLMSQPVWERYRPDRFLN 300
DGSRSYALFLYQSGGMQWDVAQRSGNPVLMGFSSGDGYFENSPLMSQPVWERYRPDRFLN
Sbjct: 190 DGSRSYALFLYQSGGMQWDVAQRSGNPVLMGFSSGDGYFENSPLMSQPVWERYRPDRFLN 249
Query: 301 SNSGLQGLQFYRLHREERPNYRLECLQWLKSQPRWPSWGWNQVSCPCSWQQGRRDLRFQP 360
SNSGLQGLQFYRLHREERPNYRLECLQWLKSQPRWPSWGWNQVSCPCSWQQGRRDLRFQP
Sbjct: 250 SNSGLQGLQFYRLHREERPNYRLECLQWLKSQPRWPSWGWNQVSCPCSWQQGRRDLRFQP 309
Query: 361 VSIGRWGLGSRQLCSFTSWRGGVCCSYGPWGEFREGWHVQRPWQLAQELEPQSWCCRWND 420
VSIGRWGLGSRQLCSFTSWRGGVCCSYGPWGEFREGWHVQRPWQLAQELEPQSWCCRWND
Sbjct: 310 VSIGRWGLGSRQLCSFTSWRGGVCCSYGPWGEFREGWHVQRPWQLAQELEPQSWCCRWND 369
Query: 421 KPYLCALYQQRRPHVGCATYRPPQPAWMFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNS 480
KPYLCALYQQRRPHVGCATYRPPQPAWMFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNS
Sbjct: 370 KPYLCALYQQRRPHVGCATYRPPQPAWMFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNS 429
Query: 481 SFLLQGRTAQTGSAQATNFIAFAAQYRSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPD 540
SFLLQGRTAQTGSAQATNFIAFAAQYRSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPD
Sbjct: 430 SFLLQGRTAQTGSAQATNFIAFAAQYRSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPD 489
Query: 541 HEDGGGQETFNATGVLLSRNGSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGL 600
HEDGGGQETFNATGVLLSRNGSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGL
Sbjct: 490 HEDGGGQETFNATGVLLSRNGSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGL 549
Query: 601 LGVWNNNPEDDFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVFY 660
LGVWNNNPEDDFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVFY
Sbjct: 550 LGVWNNNPEDDFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVFY 609
Query: 661 SQLQKNSSWAEHLISNCDGDSSCIYDTLALRNASIGLHTREVSKNYEQANATLNQYPPSI 720
SQLQKNSSWAEHLISNCDGDSSCIYDTLALRNASIGLHTREVSKNYEQANATLNQYPPSI
Sbjct: 610 SQLQKNSSWAEHLISNCDGDSSCIYDTLALRNASIGLHTREVSKNYEQANATLNQYPPSI 669
Query: 721 NGGRVIEAYKGQTTLIQYTSNAEDANFTLRDSCTDLELFENGTLLWTPKSLEPFTLEILA 780
NGGRVIEAYKGQTTLIQYTSNAEDANFTLRDSCTDLELFENGTLLWTPKSLEPFTLEILA
Sbjct: 670 NGGRVIEAYKGQTTLIQYTSNAEDANFTLRDSCTDLELFENGTLLWTPKSLEPFTLEILA 729
Query: 781 RSAKIGLASALQPRTVVCHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSED 840
RSAKIGLASALQPRTVVCHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSED
Sbjct: 730 RSAKIGLASALQPRTVVCHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSED 789
Query: 841 ACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYIS 900
ACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYIS
Sbjct: 790 ACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYIS 849
Query: 901 QTLGCQPMCTCPPAFTDSRCFLAGNNFSPTVNLELPLRVIQLLLSEEENASMAEVNASVA 960
QTLGCQPMCTCPPAFTDSRCFLAGNNFSPTVNLELPLRVIQLLLSEEENASMAEVNASVA
Sbjct: 850 QTLGCQPMCTCPPAFTDSRCFLAGNNFSPTVNLELPLRVIQLLLSEEENASMAEVNASVA 909
Query: 961 YRLGTLDMRAFLRNSQVERIDSAAPASGSPIQHWMVISEFQYRPRGPVIDFLNNQLLAAV 1020
YRLGTLDMRAFLRNSQVERIDSAAPASGSPIQHWMVISEFQYRPRGPVIDFLNNQLLAAV
Sbjct: 910 YRLGTLDMRAFLRNSQVERIDSAAPASGSPIQHWMVISEFQYRPRGPVIDFLNNQLLAAV 969
Query: 1021 VEAFLYHVPRRSEEPRNDVVFQPISGEDVRDVTALNVSTLKAYFRCDGYKGYDLVYSPQS 1080
VEAFLYHVPRRSEEPRNDVVFQPISGEDVRDVTALNVSTLKAYFRCDGYKGYDLVYSPQS
Sbjct: 970 VEAFLYHVPRRSEEPRNDVVFQPISGEDVRDVTALNVSTLKAYFRCDGYKGYDLVYSPQS 1029
Query: 1081 GFTCVSPCSRGYCDHGGQCQHLPSGPRCSCVSFSIYTAWGEHCEHLSMKLDAFFGIFFGA 1140
GFTCVSPCSRGYCDHGGQCQHLPSGPRCSCVSFSIYTAWGEHCEHLSMKLDAFFGIFFGA
Sbjct: 1030 GFTCVSPCSRGYCDHGGQCQHLPSGPRCSCVSFSIYTAWGEHCEHLSMKLDAFFGIFFGA 1089
Query: 1141 LGGLLLLGVGTFVVLRFWGCSGARFSYFLNSAEALP 1176
LGGLLLLGVGTFVVLRFWGCSGARFSYFLNSAEALP
Sbjct: 1090 LGGLLLLGVGTFVVLRFWGCSGARFSYFLNSAEALP 1125
>gi|10092665 sushi domain containing 2 [Homo sapiens]
Length = 822
Score = 140 bits (354), Expect = 5e-33
Identities = 130/477 (27%), Positives = 189/477 (39%), Gaps = 70/477 (14%)
Query: 322 RLECLQWLKSQPRWPSWGWNQVSCPCSWQQGRRD-----------------LRFQPVSI- 363
R +C W + + + P++ CPC+ Q R D + P ++
Sbjct: 290 RTQCQAWEELEDQLPNFLEELPDCPCTLTQARADSGRFFTDYGCDMEQGSVCTYHPGAVH 349
Query: 364 ------GRWGLGSRQLCSFTS---------WRGGVCCSYG-PWGE--FREGWHVQRPWQL 405
GS Q C +T+ GG G WG FR V
Sbjct: 350 CVRSVQASLRYGSGQQCCYTADGTQLLTADSSGGSTPDRGHDWGAPPFRTPPRVPSMSHW 409
Query: 406 AQELEPQSWCCRWNDKPYLCALYQQRRPHVGCATYRPPQPAWMFGDPHITTLDGVSYTFN 465
++ +CC W C Y QRRP C YRPP+ A FGDPH T DG ++TFN
Sbjct: 410 LYDVLSFYYCCLWAPD---CPRYMQRRPSNDCRNYRPPRLASAFGDPHFVTFDGTNFTFN 466
Query: 466 GLGDFLLVGA--QDGNSSFLLQGRTAQTGS-AQATNFIAFAAQYRSSSLGPVTVQWLLEP 522
G G+++L+ A D Q T G+ + T A A Q +S + V L
Sbjct: 467 GRGEYVLLEAALTDLRVQARAQPGTMSNGTETRGTGLTAVAVQEGNSDVVEVR---LANR 523
Query: 523 HDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLS-RNGSEVSASFDGWATVSVIALSN 581
+ VLL+ + ++F Q + G+ LS G VS A + V
Sbjct: 524 TGGLEVLLNQEVLSFTE-------QSWMDLKGMFLSVAAGDRVSIMLASGAGLEVSVQGP 576
Query: 582 ILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIPPGSPEEMLFHFGMTWQI-NG 640
L S LP ++ T GLLG NN+P DDF + +G +PPG+ + LF FG W + N
Sbjct: 577 FLSVSVLLPEKFLTHTHGLLGTLNNDPTDDFTLHSGRVLPPGTSPQELFLFGANWTVHNA 636
Query: 641 TGLLGKRNDQLPSN----------FTPVFYSQLQKNSSWAEHLISNCDGDSSCIYDTLAL 690
+ LL + L N F P+F S+ N S A+ C D C +D A
Sbjct: 637 SSLLTYDSWFLVHNFLYQPKHDPTFEPLFPSETTLNPSLAQEAAKLCGDDHFCNFDVAAT 696
Query: 691 RNASIGLHTREVSKNYEQANATLNQ------YPPSINGGRVIEAYKGQTTLIQYTSN 741
+ S G TR + +++ +L P NG + Y +T+ + N
Sbjct: 697 GSLSTGTATRVAHQLHQRRMQSLQPVVSCGWLAPPPNGQKEGNRYLAGSTIYFHCDN 753
>gi|115298674 nidogen 1 precursor [Homo sapiens]
Length = 1247
Score = 71.2 bits (173), Expect = 5e-12
Identities = 76/267 (28%), Positives = 116/267 (43%), Gaps = 46/267 (17%)
Query: 69 AAPIPILPERGVSLFPYGAGAGDLEFVRRTVDFTSPLFKPATGFPLGSSLR-------DS 121
A P+ L + LFP+G G GDLE + DF SP + L +LR D+
Sbjct: 23 AGPVGCLSRQ--ELFPFGPGQGDLE-LEDGDDFVSPALE------LSGALRFYDRSDIDA 73
Query: 122 LYFTDNGQIIFPESDYQIFSYPNPLPTGFTGRDPVALVAPFWDDADFSTGRGTTFYQEYE 181
+Y T NG I E + S+P P F VAPF D D + G G +Y+E
Sbjct: 74 VYVTTNGIIATSEPPAKE-SHPGLFPPTF------GAVAPFLADLDTTDGLGKVYYREDL 126
Query: 182 TFYGEHSLLVQQAESWIRKMTNNGGYKARWALKVTWVNAHAYPA-----QWTLGSNTYQA 236
+ + Q+A + + ++ A+ VTW + Y NT+QA
Sbjct: 127 S-----PSITQRAAECVHRGFPEISFQPSSAVVVTWESVAPYQGPSRDPDQKGKRNTFQA 181
Query: 237 ILSTDGSRSYALFLYQSGGMQWDV--AQRSGN--PVLMGFSSGDGYFENSPLMSQPVWER 292
+L++ S SYA+FLY G+Q+ +++ N P ++ FS G F S +
Sbjct: 182 VLASSDSSSYAIFLYPEDGLQFHTTFSKKENNQVPAVVAFSQGSVGF---LWKSNGAYNI 238
Query: 293 YRPDR------FLNSNSGLQGLQFYRL 313
+ DR +SNSG QG+ + +
Sbjct: 239 FANDRESVENLAKSSNSGQQGVWVFEI 265
Score = 39.3 bits (90), Expect = 0.022
Identities = 44/163 (26%), Positives = 56/163 (34%), Gaps = 62/163 (38%)
Query: 807 LYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEEPCFPSVH-------CVPGK--- 856
LYNQ ++ +L + G EGS DA + PC+ H C PG
Sbjct: 641 LYNQEEKILRYALS--------NSIGPVREGSPDALQNPCYIGTHGCDTNAACRPGPRTQ 692
Query: 857 -GCEACPPNLTGDGRHC----------AALGSSFLCQNQ------------------SC- 886
CE C GDGR C + GS +C N +C
Sbjct: 693 FTCE-CSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCV 751
Query: 887 ------PVNYCYNQGH-CYISQ------TLGCQPMCTCPPAFT 916
P+NYC H C I Q T G C+C P F+
Sbjct: 752 AVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFS 794
Score = 32.7 bits (73), Expect = 2.1
Identities = 23/79 (29%), Positives = 29/79 (36%), Gaps = 12/79 (15%)
Query: 798 CHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFG--RYCEGSEDACEEPCFPSVHC--V 853
C +QC+Y G SS C C G G + C+ ++ C P C
Sbjct: 769 CDIPQRAQCIYT-----GGSSYT---CSCLPGFSGDGQACQDVDECQPSRCHPDAFCYNT 820
Query: 854 PGKGCEACPPNLTGDGRHC 872
PG C P GDG C
Sbjct: 821 PGSFTCQCKPGYQGDGFRC 839
Score = 32.0 bits (71), Expect = 3.6
Identities = 23/78 (29%), Positives = 32/78 (41%), Gaps = 12/78 (15%)
Query: 834 YCEGSEDACEEPCFPSVHCVPGKGCE---ACPPNLTGDGRHCAALGSSFLCQNQSC-PVN 889
YCE C+ P C+ G +C P +GDG+ C + CQ C P
Sbjct: 761 YCETGLHNCDIP--QRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDE---CQPSRCHPDA 815
Query: 890 YCYNQGHCYISQTLGCQP 907
+CYN + Q C+P
Sbjct: 816 FCYNTPGSFTCQ---CKP 830
>gi|144953895 nidogen 2 precursor [Homo sapiens]
Length = 1375
Score = 68.6 bits (166), Expect = 3e-11
Identities = 72/251 (28%), Positives = 109/251 (43%), Gaps = 35/251 (13%)
Query: 82 LFPYGAGAGDLEFVRRTVDFTSPLFKPATGFPLGSSLRDSLYFTDNGQII---FP-ESDY 137
LFP+G GD + ++ D +S + K A + +LY NG I FP E+ Y
Sbjct: 36 LFPHGESWGD-QLLQEGDDESSAVVKLANPLHFYEARFSNLYVGTNGIISTQDFPRETQY 94
Query: 138 QIFSYPNPLPTGFTGRDPVALVAPFWDDADFSTGRGTTFYQEYETFYGEHSLLVQQAESW 197
+ +P P +APF D D S GRG Y+E + ++ A +
Sbjct: 95 VDYDFPTDFPA----------IAPFLADIDTSHGRGRVLYREDTS-----PAVLGLAARY 139
Query: 198 IRK-MTNNGGYKARWALKVTWVNAHAYPA--QWTLGS---NTYQAILSTDGSRSYALFLY 251
+R + + A TW AY + L S NT+QA+L++DGS SYALFLY
Sbjct: 140 VRAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELNTFQAVLASDGSDSYALFLY 199
Query: 252 QSGGMQW--DVAQRSGN-----PVLMGFSSG--DGYFENSPLMSQPVWERYRPDRFLNSN 302
+ G+Q+ + S N P +GF G D P S E+ + + SN
Sbjct: 200 PANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKSEGPYFSLTSTEQSVKNLYQLSN 259
Query: 303 SGLQGLQFYRL 313
G+ G+ + +
Sbjct: 260 LGIPGVWAFHI 270
Score = 33.1 bits (74), Expect = 1.6
Identities = 22/76 (28%), Positives = 28/76 (36%), Gaps = 6/76 (7%)
Query: 832 GRYCEGSEDACEEPCFPSVHC--VPGKGCEACPPNLTGDGRHCAALGSSFL--CQNQS-- 885
G C ++ E C P+ C PG C P GDG C +S L C+ Q
Sbjct: 887 GHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPCEQQQRH 946
Query: 886 CPVNYCYNQGHCYISQ 901
Y Y +I Q
Sbjct: 947 AQAQYAYPGARFHIPQ 962
>gi|134268640 tectorin alpha precursor [Homo sapiens]
Length = 2155
Score = 58.9 bits (141), Expect = 3e-08
Identities = 48/153 (31%), Positives = 66/153 (43%), Gaps = 17/153 (11%)
Query: 121 SLYFTDNGQIIFPESDYQIFSYPNPLPTGFTGRDPVALVAPFWDDADFSTG-RGTTFYQE 179
++Y +NG + F Q P F D A VAPFW AD G RG +Y+E
Sbjct: 64 TVYVNNNGVVSFNVLVSQF------TPESFPLTDGRAFVAPFW--ADVHNGIRGEIYYRE 115
Query: 180 YETFYGEHSLLVQQAESWIRKMTNN-GGYKARWALKVTWVNAHAYPAQWTLGSNTYQAIL 238
++++A IRK + + A W VTW Y T NT+QA+L
Sbjct: 116 TM-----EPAILKRATKDIRKYFKDMATFSATWVFIVTWEEVTFYGGSSTTPVNTFQAVL 170
Query: 239 STDGSRSYALFLYQSGGMQWDVAQRSGNPVLMG 271
+DGS ++ LF Y + W SG L G
Sbjct: 171 VSDGSYTFTLFNYYE--INWTTGTASGGDPLTG 201
Score = 48.1 bits (113), Expect = 5e-05
Identities = 50/198 (25%), Positives = 76/198 (38%), Gaps = 36/198 (18%)
Query: 448 MFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQYR 507
+FG+PH T DG + F G + ++LL + QT S + A R
Sbjct: 324 VFGEPHYHTFDGFLFHFQG------------SCAYLLARQCLQTSSLPFFSVEAKNEHRR 371
Query: 508 SSSLG-------PVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRN 560
S++ V +L P + + N VT P D G + + +
Sbjct: 372 GSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVET 431
Query: 561 GSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTI 620
+ +FDG +AS S+P Y N T GL G +N NP DDF P+
Sbjct: 432 DFGLLVTFDGQH-----------YASISVPGSYINSTCGLCGNYNKNPLDDFLRPD---- 476
Query: 621 PPGSPEEMLFHFGMTWQI 638
G P + G +W++
Sbjct: 477 --GRPAMSVLDLGESWRV 492
Score = 40.8 bits (94), Expect = 0.008
Identities = 78/312 (25%), Positives = 111/312 (35%), Gaps = 48/312 (15%)
Query: 586 SASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLG 645
S ++P QN T GL G +N NP+DD MP G + S E FG +W T
Sbjct: 1226 SITVPRSMQNSTYGLCGRYNGNPDDDLEMPMG--LLASSVNE----FGQSWVKRDTFCQV 1279
Query: 646 KRNDQLPSNFTPVFYSQLQKNSSWAEHLISNCDGDSSCIYDTLALRNASIGLHTREVSKN 705
D+ PS +S++Q+ S LI N +NA+ +V+
Sbjct: 1280 GCGDRCPSCAKVEGFSKVQQLCS----LIPN--------------QNAAFSKCHSKVNPT 1321
Query: 706 YEQANATLNQYPPSINGGRVIEAYKGQTTLIQYTSNAEDANFTLRDSCTDLELFENGTLL 765
+ N + I+GG V A + L Y S + T+ T + + T+
Sbjct: 1322 FFYKNCL---FDSCIDGGAVQTAC---SWLQNYASTCQTQGITV----TGWRNYTSCTVT 1371
Query: 766 WTPKS-LEPFTLEILARSAKIGLASALQPRTVV-CHCNAESQCLYNQTSRVGNSSLEVAG 823
P S E R A I L S V CHC+A L ++ + +S G
Sbjct: 1372 CPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDA-GYVLNGKSCILPHS----CG 1426
Query: 824 CKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQN 883
C D G+Y E + C C + C P CA C
Sbjct: 1427 CYSD----GKYYEPKQLFWNSDCTRRCRCF-RRNVIQCDPRQCKSDEECALRNGVRGC-- 1479
Query: 884 QSCPVNYCYNQG 895
S +YC G
Sbjct: 1480 FSTKTSYCLAAG 1491
Score = 33.1 bits (74), Expect = 1.6
Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 8/77 (10%)
Query: 546 GQET----FNATGVL-LSRNGSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGL 600
GQE F+ +G L + RN + + G TV S+I L Y N T GL
Sbjct: 792 GQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQY---SDIGLLYIRLSTTYFNCTGGL 848
Query: 601 LGVWNNNPEDDFRMPNG 617
G +N N D+F +PNG
Sbjct: 849 CGFYNANASDEFCLPNG 865
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 57.8 bits (138), Expect = 6e-08
Identities = 54/205 (26%), Positives = 82/205 (40%), Gaps = 24/205 (11%)
Query: 83 FPYGAGAGDLEFVRRTVDFTSPLFKPATGFPLGSSLRDSLYFTDNGQIIFPESDYQIFSY 142
+P+GA GD ++ D S L + FP + LY +NG I F + Q
Sbjct: 32 YPFGAERGDAVTPKQD-DGGSGLRPLSVPFPFFGAEHSGLYVNNNGIISFLKEVSQF--- 87
Query: 143 PNPLPTGFTGRDPVALVAPFWDDADFSTGRGTTFYQEYETFYGEHSLLVQQAESWIRKMT 202
P F +VA FW D D + G +Y+E + ++L + E
Sbjct: 88 ---TPVAFPIAKDRCVVAAFWADVD-NRRAGDVYYREAT----DPAMLRRATEDVRHYFP 139
Query: 203 NNGGYKARWALKVTWVNAHAYPAQWTLGSNTYQAILSTDGSRSYALFLYQSGGMQWDV-- 260
+ A W TW + + NT+Q +L TDG S+ +F Y+S + W
Sbjct: 140 ELLDFNATWVFVATWYRVTFFGGSSSSPVNTFQTVLITDGKLSFTIFNYES--IVWTTGT 197
Query: 261 -AQRSGNPVLM-------GFSSGDG 277
A GN + GF++GDG
Sbjct: 198 HASSGGNATGLGGIAAQAGFNAGDG 222
Score = 50.4 bits (119), Expect = 1e-05
Identities = 39/136 (28%), Positives = 50/136 (36%), Gaps = 16/136 (11%)
Query: 799 HCNAESQCLYNQTSRVGNSSLEVAG---CKCDGGTFGRYCEGSEDACE-EPCFPSVHCVP 854
HC E R G S + G C+C G G +CE DAC+ PC C
Sbjct: 787 HCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCES 846
Query: 855 GKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPA 914
G G C + G HC + + C + C +G+C S CTC
Sbjct: 847 GGGAYLCVCPESFFGYHCETV-------SDPCFSSPCGGRGYCLASNG---SHSCTCKVG 896
Query: 915 FTDSRCFLAGNNFSPT 930
+T C A F PT
Sbjct: 897 YTGEDC--AKELFPPT 910
Score = 44.7 bits (104), Expect = 5e-04
Identities = 33/113 (29%), Positives = 46/113 (40%), Gaps = 13/113 (11%)
Query: 824 CKCDGGTFGRYCEGSED--ACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLC 881
C+C G G++CE + PC C G C GRHC +
Sbjct: 565 CECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCE------IG 618
Query: 882 QNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRCFLAGNNF--SPTVN 932
+ SC C+N G C+ +G + C CPP F+ C +A + SP VN
Sbjct: 619 KPDSCASGPCHNGGTCF--HYIG-KYKCDCPPGFSGRHCEIAPSPCFRSPCVN 668
Score = 41.6 bits (96), Expect = 0.004
Identities = 34/126 (26%), Positives = 46/126 (36%), Gaps = 17/126 (13%)
Query: 800 CNAESQCLYNQTSRVGNSSLEVAG--CKCDGGTFGRYCEGSEDACE-EPCFPSVHC--VP 854
C +C G+ VAG C C G G +CE D C PC C +P
Sbjct: 751 CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLP 810
Query: 855 GKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPA 914
G CP G HC + +C + C + G C ++ G +C CP +
Sbjct: 811 GAYVCRCPAGFV--GVHCET-------EVDACDSSPCQHGGRC---ESGGGAYLCVCPES 858
Query: 915 FTDSRC 920
F C
Sbjct: 859 FFGYHC 864
Score = 37.7 bits (86), Expect = 0.065
Identities = 35/134 (26%), Positives = 43/134 (32%), Gaps = 40/134 (29%)
Query: 798 CHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKG 857
C C +CL T+ C+C G FG CE A PC + C
Sbjct: 472 CECRNGGRCLGANTTL----------CQCPLGFFGLLCEFEITAM--PCNMNTQC----- 514
Query: 858 CEACPPNLTGDGRHCAALGSSFLC-----QNQS------CPVNYCYNQGHCYISQTLGCQ 906
DG +C G S+LC N S C + C+N G C
Sbjct: 515 ---------PDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDD---S 562
Query: 907 PMCTCPPAFTDSRC 920
C CP F C
Sbjct: 563 YTCECPRGFHGKHC 576
Score = 32.0 bits (71), Expect = 3.6
Identities = 19/50 (38%), Positives = 20/50 (40%), Gaps = 10/50 (20%)
Query: 1064 FRCDGYKGYDLVYSPQSGFTCV---SPCSRGYCDHGGQCQHLPSGPRCSC 1110
FRC G+ G TC SPC C HGGQCQ C C
Sbjct: 333 FRCQCPAGF-------GGPTCETAQSPCDTKECQHGGQCQVENGSAVCVC 375
Score = 32.0 bits (71), Expect = 3.6
Identities = 15/37 (40%), Positives = 17/37 (45%), Gaps = 4/37 (10%)
Query: 1088 CSRGYCDHGGQCQHLPSGPRCSCVSFSIYTAWGEHCE 1124
CS G C +GG C+ CSC Y G HCE
Sbjct: 584 CSSGPCRNGGTCKEAGGEYHCSCP----YRFTGRHCE 616
Score = 30.8 bits (68), Expect = 7.9
Identities = 31/128 (24%), Positives = 39/128 (30%), Gaps = 18/128 (14%)
Query: 798 CHCN----AESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACE-EPCFPSVHC 852
CH + A C T G +S C+C G G CE ++ C+ + C C
Sbjct: 308 CHLDVNECASQPCQNGGTCTHGINSFR---CQCPAGFGGPTCETAQSPCDTKECQHGGQC 364
Query: 853 VPGKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCP 912
G C G C C + C N G C L C C
Sbjct: 365 QVENGSAVCVCQAGYTGAACE-------MDVDDCSPDPCLNGGSCV---DLVGNYTCLCA 414
Query: 913 PAFTDSRC 920
F RC
Sbjct: 415 EPFKGLRC 422
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 55.5 bits (132), Expect = 3e-07
Identities = 38/125 (30%), Positives = 52/125 (41%), Gaps = 19/125 (15%)
Query: 799 HCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDAC-EEPCFP--SVHCVPG 855
HC QC+ R+G S C+C G G CEG + C PC S+ C+
Sbjct: 1234 HCLNGGQCM----DRIGGYS-----CRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQL 1284
Query: 856 KGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAF 915
C GRHC +F+ CP C N G C ++ + +C CPP F
Sbjct: 1285 TNDYLCVCRSAFTGRHC----ETFV---DVCPQMPCLNGGTCAVASNMPDGFICRCPPGF 1337
Query: 916 TDSRC 920
+ +RC
Sbjct: 1338 SGARC 1342
Score = 45.4 bits (106), Expect = 3e-04
Identities = 37/122 (30%), Positives = 48/122 (39%), Gaps = 17/122 (13%)
Query: 804 SQCLYNQTSRVGNSSLEVAG--CKCDGGTFGRYCEGSEDAC-EEPCFPSVHCVPGKGCEA 860
++CL G S V CKC G G +CE + + C E CF CV G +
Sbjct: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFS 1010
Query: 861 --CPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDS 918
CP T GS L + C + C N+G C LG C+CP +T
Sbjct: 1011 CLCPVGFT---------GSFCLHEINECSSHPCLNEGTCV--DGLGTY-RCSCPLGYTGK 1058
Query: 919 RC 920
C
Sbjct: 1059 NC 1060
Score = 45.1 bits (105), Expect = 4e-04
Identities = 42/154 (27%), Positives = 58/154 (37%), Gaps = 39/154 (25%)
Query: 803 ESQCLYNQTSRVGNSSLEVAG--CKCDGGTFGRYCEGSEDAC-------EEPCFPSV--- 850
+++CL N G V G C C G G C+ + D C + CF +
Sbjct: 758 KNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGY 817
Query: 851 --HCV---PGKGCEA----CPPNLTGDGRHCAALGS--SFLC------QNQSCPVNY--- 890
HCV GK C+ C PN + C + S+ C Q Q C ++
Sbjct: 818 TCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDEC 877
Query: 891 ----CYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
C N G C+ +Q MC CPP F+ C
Sbjct: 878 ISKPCMNHGLCHNTQG---SYMCECPPGFSGMDC 908
Score = 43.5 bits (101), Expect = 0.001
Identities = 76/328 (23%), Positives = 114/328 (34%), Gaps = 64/328 (19%)
Query: 803 ESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEE-PCFPSVHCVPGKGCEAC 861
ES C T G +S C C G G +C + C PC CV G G C
Sbjct: 993 ESSCFNGGTCVDGINSFS---CLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRC 1049
Query: 862 PPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRCF 921
L G++C L + LC C N+G C + + C CP + + C
Sbjct: 1050 SCPLGYTGKNCQTLVN--LCSRSPCK-----NKGTCVQKK---AESQCLCPSGWAGAYCD 1099
Query: 922 LAGNNFSPTVNLELPLRVIQLLLSEEENASMAEVNASVAYRLGTLDMRAFLRNSQVERID 981
+ P V+ ++ +L+ S +NA + + + E++D
Sbjct: 1100 V------PNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQC--PLGYTGSYCEEQLD 1151
Query: 982 SAAPASGSPIQHWMVISEFQYRPRGPVIDFLNNQLLAAVVEAFLYHVPRRSEEPRNDVVF 1041
A +P QH S DF+ V + +E +N
Sbjct: 1152 ECA---SNPCQHGATCS-----------DFIGGYRCECVPGYQGVNCEYEVDECQN---- 1193
Query: 1042 QPISGEDVRDVTALNVSTLKAYFRCDGYKGYDLVYSPQSGFTC---VSPCSRG-YCDHGG 1097
QP T ++ L +F+C G G C + C+RG +C +GG
Sbjct: 1194 QPCQNGG----TCID---LVNHFKCSCPPG-------TRGLLCEENIDDCARGPHCLNGG 1239
Query: 1098 QCQHLPSGPRCSCV-SFSIYTAWGEHCE 1124
QC G C C+ F+ GE CE
Sbjct: 1240 QCMDRIGGYSCRCLPGFA-----GERCE 1262
Score = 42.4 bits (98), Expect = 0.003
Identities = 42/135 (31%), Positives = 53/135 (39%), Gaps = 29/135 (21%)
Query: 795 TVVCHCNAESQCLYNQTSRVGNSSLEVAG---CKCDGGTFGRYCEGSEDACEEPCFPSVH 851
T V C+ C + G + L + G C+C G G+YC D+ PC PS
Sbjct: 181 TDVNECDIPGHCQH------GGTCLNLPGSYQCQCPQGFTGQYC----DSLYVPCAPSP- 229
Query: 852 CVPGKGCEACPPNLTGDGR-HCAAL----GSSFLCQNQSCPVNYCYNQGHCYIS-QTLGC 905
CV G C TGD C L GS+ CP + C N G C T C
Sbjct: 230 CVNGGTCRQ-----TGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNC 284
Query: 906 QPMCTCPPAFTDSRC 920
+ CPP +T C
Sbjct: 285 R----CPPQWTGQFC 295
Score = 41.2 bits (95), Expect = 0.006
Identities = 40/152 (26%), Positives = 56/152 (36%), Gaps = 37/152 (24%)
Query: 804 SQCLYNQTSRVGN-SSLEVAG---CKCDGGTFGRYCEGSEDACEE-PCFPSVHC-----V 853
++CL N S G+ +++ C C GR+CE D C + PC C +
Sbjct: 1266 NECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNM 1325
Query: 854 PGKGCEACPPNLTG-------------DGRHCA--ALGSSFLCQN-----QSCPVNYCYN 893
P CPP +G G C A G C + C + C +
Sbjct: 1326 PDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQH 1385
Query: 894 QGHCYISQTLGCQP---MCTCPPAFTDSRCFL 922
G C+ + QP C C P F+ SRC L
Sbjct: 1386 GGSCHPQR----QPPYYSCQCAPPFSGSRCEL 1413
Score = 39.3 bits (90), Expect = 0.022
Identities = 38/128 (29%), Positives = 50/128 (39%), Gaps = 19/128 (14%)
Query: 800 CNAESQCLYNQTSRVGNSSLEVAG---CKCDGGTFGRYCEGSEDACEEP--CFPSVHC-- 852
C CL + + G++ VA CKC G G+ CE + C+ P C C
Sbjct: 142 CQWTDACLSHPCAN-GSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLN 200
Query: 853 VPGKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCP 912
+PG CP T G++C +L C + C N G C QT C C
Sbjct: 201 LPGSYQCQCPQGFT--GQYCDSL-------YVPCAPSPCVNGGTC--RQTGDFTFECNCL 249
Query: 913 PAFTDSRC 920
P F S C
Sbjct: 250 PGFEGSTC 257
Score = 39.3 bits (90), Expect = 0.022
Identities = 30/108 (27%), Positives = 39/108 (36%), Gaps = 11/108 (10%)
Query: 824 CKCDGGTFGRYCEGSEDACE-EPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQ 882
C+C G G CE + C +PC C+ G C G HC +
Sbjct: 442 CECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCEL-------E 494
Query: 883 NQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRCFLAGNNFSPT 930
C N C N G C + C CPP FT C + ++ S T
Sbjct: 495 INECQSNPCVNNGQCVDKVN---RFQCLCPPGFTGPVCQIDIDDCSST 539
Score = 39.3 bits (90), Expect = 0.022
Identities = 17/33 (51%), Positives = 18/33 (54%)
Query: 1080 SGFTCVSPCSRGYCDHGGQCQHLPSGPRCSCVS 1112
SG C S C + C G QC H SGPRC C S
Sbjct: 1338 SGARCQSSCGQVKCRKGEQCVHTASGPRCFCPS 1370
Score = 38.5 bits (88), Expect = 0.038
Identities = 34/129 (26%), Positives = 44/129 (34%), Gaps = 35/129 (27%)
Query: 824 CKCDGGTFGRYCEGSEDAC-EEPCFPSVHCVPGKGCEA--CPPNLTGD------------ 868
C+C G G CE D C PC C+ G + C P TGD
Sbjct: 897 CECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSE 956
Query: 869 ----GRHCAALGSSFLCQNQS-------------CPVNYCYNQGHCYISQTLGCQPMCTC 911
G C+ +S+ C+ Q+ C + C+N G C C C
Sbjct: 957 PCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGIN---SFSCLC 1013
Query: 912 PPAFTDSRC 920
P FT S C
Sbjct: 1014 PVGFTGSFC 1022
Score = 37.7 bits (86), Expect = 0.065
Identities = 49/207 (23%), Positives = 60/207 (28%), Gaps = 85/207 (41%)
Query: 788 ASALQPRTVVCHCNAESQCL--YNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEE- 844
A ALQ R C E C+ +N T CKC G G YC+ D CE+
Sbjct: 23 AHALQCRDGYEPCVNEGMCVTYHNGTGY----------CKCPEGFLGEYCQ-HRDPCEKN 71
Query: 845 ------------------------------------PCFPSVHCVPGKGC---------- 858
PCF S C+ G C
Sbjct: 72 RCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYEC 131
Query: 859 --------------EACPPNLTGDGRHCAALGSSFLCQ------NQSC--PVNYCYNQGH 896
+AC + +G C + + F C+ Q C VN C GH
Sbjct: 132 TCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGH 191
Query: 897 CYISQTLGCQP---MCTCPPAFTDSRC 920
C T P C CP FT C
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYC 218
Score = 36.2 bits (82), Expect = 0.19
Identities = 28/99 (28%), Positives = 38/99 (38%), Gaps = 10/99 (10%)
Query: 823 GCKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQ 882
GC C G G C + D C F S C PG C + C + LC
Sbjct: 323 GCVCVNGWSGDDCSENIDDC---AFAS--CTPGS---TCIDRVASFSCMCPEGKAGLLCH 374
Query: 883 -NQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
+ +C N C+ C + G Q +CTCP + + C
Sbjct: 375 LDDACISNPCHKGALCDTNPLNG-QYICTCPQGYKGADC 412
Score = 33.9 bits (76), Expect = 0.94
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 9/70 (12%)
Query: 1058 STLKAYFRCDGYKGYDLVYSPQSGFTCVSPCS-RGYCDHGGQCQHLPSGPRCSCVSFSIY 1116
+T+ F C G+ + Q T V+ C G+C HGG C +LP +C C
Sbjct: 160 TTVANQFSCKCLTGF----TGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQ---- 211
Query: 1117 TAWGEHCEHL 1126
G++C+ L
Sbjct: 212 GFTGQYCDSL 221
Score = 33.9 bits (76), Expect = 0.94
Identities = 35/122 (28%), Positives = 47/122 (38%), Gaps = 18/122 (14%)
Query: 804 SQCLYNQTSRVGNSSLEVAG--CKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKGCEAC 861
++CL N GN + ++G C CD G G CE ++ C S C G C+
Sbjct: 722 NECLSNPCIH-GNCTGGLSGYKCLCDAGWVGINCEVDKNEC-----LSNPCQNGGTCD-- 773
Query: 862 PPNLTGDGRHCAALG-SSFLCQ--NQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDS 918
NL R G + CQ C N C NQG C+ + C C +T
Sbjct: 774 --NLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDIS---GYTCHCVLPYTGK 828
Query: 919 RC 920
C
Sbjct: 829 NC 830
Score = 33.5 bits (75), Expect = 1.2
Identities = 29/98 (29%), Positives = 36/98 (36%), Gaps = 12/98 (12%)
Query: 824 CKCDGGTFGRYCEGSEDACE-EPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQ 882
C+C G G CE + D C+ +PC C G C N G C+ Q
Sbjct: 556 CQCATGFTGVLCEENIDNCDPDPCHHG-QCQDGIDSYTCICNPGYMGAICSD-------Q 607
Query: 883 NQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
C + C N G C I G Q C C P + C
Sbjct: 608 IDECYSSPCLNDGRC-IDLVNGYQ--CNCQPGTSGVNC 642
Score = 33.5 bits (75), Expect = 1.2
Identities = 27/101 (26%), Positives = 34/101 (33%), Gaps = 18/101 (17%)
Query: 824 CKCDGGTFGRYCEGSEDAC-EEPCFPSVHCVP---GKGCEACPPNLTGDGRHCAALGSSF 879
C C+ G G C D C PC C+ G C C P +G +C
Sbjct: 593 CICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCN-CQPGTSGV--NCEINFDD- 648
Query: 880 LCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
C + C C + + Y C C P FT RC
Sbjct: 649 -CASNPCIHGICMDGINRY---------SCVCSPGFTGQRC 679
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 53.5 bits (127), Expect = 1e-06
Identities = 45/166 (27%), Positives = 69/166 (41%), Gaps = 24/166 (14%)
Query: 771 LEPFTLEILARSAKIGLASALQPRTVVCHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGT 830
++P +L +L + S ++PR ++C E C T + SL C+C G
Sbjct: 1 MQPPSLLLLLLLLLLLCVSVVRPRGLLCGSFPEP-CANGGTCL--SLSLGQGTCQCAPGF 57
Query: 831 FGRYCEGSEDACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQ-------- 882
G C+ +PC + C G C+A P G + L SFLC
Sbjct: 58 LGETCQ-----FPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGE 112
Query: 883 ------NQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRCFL 922
CP ++C +G C+I Q G +P C+C P +T +C L
Sbjct: 113 RCQAKLEDPCPPSFCSKRGRCHI-QASG-RPQCSCMPGWTGEQCQL 156
Score = 47.4 bits (111), Expect = 8e-05
Identities = 38/143 (26%), Positives = 54/143 (37%), Gaps = 14/143 (9%)
Query: 786 GLASALQPRTVVCHCNAE-SQCLYNQTSRVGNSSLEVAG----CKCDGGTFGRYCEGSED 840
G A P V C + +CL G ++ C+C G G++CE D
Sbjct: 989 GFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEID 1048
Query: 841 ACE-EPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQNQ--SCPVNYCYNQGHC 897
C +PCF G CEA + G HC C ++ SC ++C++ G C
Sbjct: 1049 PCHSQPCFH------GGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLC 1102
Query: 898 YISQTLGCQPMCTCPPAFTDSRC 920
S G P C C + C
Sbjct: 1103 LPSPKPGFPPRCACLSGYGGPDC 1125
Score = 46.6 bits (109), Expect = 1e-04
Identities = 60/254 (23%), Positives = 78/254 (30%), Gaps = 53/254 (20%)
Query: 718 PSINGGRVIEAYKGQTTLIQYTSNAEDANFTLRDSCTDLELFENG--------TLLWTPK 769
P NGG + GQ T Q D C + +L +NG L P
Sbjct: 34 PCANGGTCLSLSLGQGTC-QCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPS 92
Query: 770 SLEPFTLEILARSAKIGLASALQPRTVVCHCNAESQCLYNQTSRVGNSSLEVAG---CKC 826
S P T L L R C E C + S+ G ++ +G C C
Sbjct: 93 SPSPLTPSFLCTC----LPGFTGER---CQAKLEDPCPPSFCSKRGRCHIQASGRPQCSC 145
Query: 827 DGGTFGRYCEGSEDACEEPC---------FPSV--HCVPGKGCEACP---------PNLT 866
G G C+ + PC +P + HC PG AC P
Sbjct: 146 MPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPC 205
Query: 867 GDGRHCAALGSSFLC-------------QNQSCPVNYCYNQGHCYISQTLGCQ-PMCTCP 912
G C SF C + CP C N G C + +C CP
Sbjct: 206 PKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCP 265
Query: 913 PAFTDSRCFLAGNN 926
P F C + +N
Sbjct: 266 PGFIGPDCEVNPDN 279
Score = 42.0 bits (97), Expect = 0.003
Identities = 39/135 (28%), Positives = 51/135 (37%), Gaps = 27/135 (20%)
Query: 798 CHCNAESQCLYNQTS----RVGNSSLEVAG---CKCDGGTFGRYCEGSEDAC-EEPCFPS 849
CH + + +CL Q G S L G C C G G CE + C +PC P
Sbjct: 429 CHQDLD-ECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPG 487
Query: 850 VHCVPGKGCE--ACPPNLTGDGRHCAALGSSFLCQNQS--CPVNYCYNQGHCYISQTLGC 905
C+ CPP L G LC+ ++ C C N C+ G
Sbjct: 488 STCLDLLATFHCLCPPGLEGQ-----------LCEVETNECASAPCLNHADCH-DLLNGF 535
Query: 906 QPMCTCPPAFTDSRC 920
Q C C P F+ +RC
Sbjct: 536 Q--CICLPGFSGTRC 548
Score = 41.6 bits (96), Expect = 0.004
Identities = 35/132 (26%), Positives = 46/132 (34%), Gaps = 36/132 (27%)
Query: 824 CKCDGGTFGRYCEGSEDACE-EPCFPSVHCVPGKG---CEACPPNLTG------------ 867
C+C G G+ C DAC+ +PC C P G C ACPP G
Sbjct: 954 CQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHC-ACPPGFVGLRCEGDVDECLD 1012
Query: 868 ------DGRHCAALGSSFLCQ------NQSCPVNY-------CYNQGHCYISQTLGCQPM 908
C +L ++F CQ Q C V C++ G C + +
Sbjct: 1013 QPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFI 1072
Query: 909 CTCPPAFTDSRC 920
C CP F C
Sbjct: 1073 CHCPKGFEGPTC 1084
Score = 40.4 bits (93), Expect = 0.010
Identities = 36/129 (27%), Positives = 46/129 (35%), Gaps = 20/129 (15%)
Query: 796 VVCHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEEPCFPSVHC--- 852
+ C S C+ RVG+ S C C G G C + +PC C
Sbjct: 360 IAATCAPGSTCI----DRVGSFS-----CLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTN 410
Query: 853 -VPGKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTC 911
+ G C P +G H L + Q P C + G C T G C C
Sbjct: 411 PLTGSTLCLCQPGYSGPTCH-QDLDECLMAQQGPSP---CEHGGSCL--NTPGSFN-CLC 463
Query: 912 PPAFTDSRC 920
PP +T SRC
Sbjct: 464 PPGYTGSRC 472
Score = 40.4 bits (93), Expect = 0.010
Identities = 32/103 (31%), Positives = 38/103 (36%), Gaps = 17/103 (16%)
Query: 822 AGCKCDGGTFGRYCEGSEDAC-EEPCFPSVHCVP---GKGCEACPPNLTGDGRHCAALGS 877
+ C CD G G CE C PC C P G C CP TG C+
Sbjct: 675 SSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNC-TCPTGYTGPT--CSE--- 728
Query: 878 SFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
+ +C C N G C S CTCPP+ T +C
Sbjct: 729 ----EMTACHSGPCLNGGSCNPSPG---GYYCTCPPSHTGPQC 764
Score = 38.5 bits (88), Expect = 0.038
Identities = 36/124 (29%), Positives = 48/124 (38%), Gaps = 12/124 (9%)
Query: 802 AESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDAC-EEPCFPSVHCV---PGKG 857
A+S C T + S + C C G G C+ D C ++PC + HC+ P
Sbjct: 811 ADSPCRNRATCQ---DSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFH 867
Query: 858 CEACPPNLTGDGRHCAALGSSFLCQNQSCPVN-YCYNQGHCYISQTLGCQPMCTCPPAFT 916
C C TG + +Q V+ C+N G C S G C CPP F
Sbjct: 868 C-LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDS---GPSYFCHCPPGFQ 923
Query: 917 DSRC 920
S C
Sbjct: 924 GSLC 927
Score = 34.3 bits (77), Expect = 0.72
Identities = 26/92 (28%), Positives = 33/92 (35%), Gaps = 17/92 (18%)
Query: 824 CKCDGGTFGRYCEGSEDAC-EEPCFPSVHC--VPGKGCEACPPNLTGDGRHCAALGSSFL 880
CKC G G C+ D C +PC C +PG CP TG L
Sbjct: 575 CKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQ-----------L 623
Query: 881 CQNQSCPVNYCYNQGHCYISQTLGCQPMCTCP 912
C+ C N C + C + + C CP
Sbjct: 624 CEVPLCAPNLCQPKQICKDQKD---KANCLCP 652
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 53.1 bits (126), Expect = 1e-06
Identities = 43/134 (32%), Positives = 53/134 (39%), Gaps = 26/134 (19%)
Query: 800 CNAE-SQCLYNQTSRVGNSSLEVAG--CKCDGGTFGRYCEGSEDAC-EEPCFPSVHCVPG 855
C E S+C N G+ + G C C G +G +CE S +C + PCF C
Sbjct: 321 CELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRER 380
Query: 856 K-----GCEACPPNLTGDGRHCAALGSSFLCQNQ--SCPVNYCYNQGHCYISQTLGCQPM 908
CE CPPN TG C+ + C N C N G C G M
Sbjct: 381 NQGANYACE-CPPNFTGSN-----------CEKKVDRCTSNPCANGGQCL---NRGPSRM 425
Query: 909 CTCPPAFTDSRCFL 922
C C P FT + C L
Sbjct: 426 CRCRPGFTGTYCEL 439
Score = 45.8 bits (107), Expect = 2e-04
Identities = 39/126 (30%), Positives = 44/126 (34%), Gaps = 17/126 (13%)
Query: 799 HCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEE-PCFPSVHCVP--- 854
+C S C T NS C C G G CE C+ PC C
Sbjct: 287 YCTHHSPCKNGATC--SNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQED 344
Query: 855 GKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPA 914
G C CPP G HC SC + C+N G C + G C CPP
Sbjct: 345 GYHC-LCPPGYYG--LHCEH-------STLSCADSPCFNGGSCR-ERNQGANYACECPPN 393
Query: 915 FTDSRC 920
FT S C
Sbjct: 394 FTGSNC 399
Score = 44.7 bits (104), Expect = 5e-04
Identities = 34/122 (27%), Positives = 43/122 (35%), Gaps = 16/122 (13%)
Query: 800 CNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCE-GSEDACEEPCFPSVHCVPGKGC 858
C QCL SR+ C+C G G YCE D PC C +
Sbjct: 411 CANGGQCLNRGPSRM---------CRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENG 461
Query: 859 EACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDS 918
C GR C S +C + C+N+ CY + +C CP F S
Sbjct: 462 LMCTCPAGFSGRRCEVRTSI-----DACASSPCFNRATCYTDLSTDTF-VCNCPYGFVGS 515
Query: 919 RC 920
RC
Sbjct: 516 RC 517
Score = 35.4 bits (80), Expect = 0.32
Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 6/41 (14%)
Query: 1085 VSPCSRGYCDHGGQCQHLPSGPRCSC-VSFSIYTAWGEHCE 1124
VS C+R C HGG C L +G C+C FS G CE
Sbjct: 441 VSDCARNPCAHGGTCHDLENGLMCTCPAGFS-----GRRCE 476
Score = 32.0 bits (71), Expect = 3.6
Identities = 19/65 (29%), Positives = 27/65 (41%), Gaps = 8/65 (12%)
Query: 1068 GYKGYDLVYSP-QSGFTC---VSPCSRGYCDHGGQCQHLPSGPRCSCVSFSIYTAWGEHC 1123
G + Y P +G C +S C C +GG C+ G C C +G HC
Sbjct: 304 GQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPP----GYYGLHC 359
Query: 1124 EHLSM 1128
EH ++
Sbjct: 360 EHSTL 364
Score = 30.8 bits (68), Expect = 7.9
Identities = 33/137 (24%), Positives = 45/137 (32%), Gaps = 23/137 (16%)
Query: 797 VCHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEEPCFPSV---HCV 853
VC + CL T + ++GC G YC + P + C+
Sbjct: 199 VCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNG----YCSKPAECLCRPGWQGRLCNECI 254
Query: 854 PGKGCE----ACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPM- 908
P GC + P T D G F Q+ +NYC + C T
Sbjct: 255 PHNGCRHGTCSTPWQCTCD----EGWGGLFCDQD----LNYCTHHSPCKNGATCSNSGQR 306
Query: 909 ---CTCPPAFTDSRCFL 922
CTC P +T C L
Sbjct: 307 SYTCTCRPGYTGVDCEL 323
>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
Length = 5405
Score = 52.8 bits (125), Expect = 2e-06
Identities = 68/275 (24%), Positives = 103/275 (37%), Gaps = 52/275 (18%)
Query: 381 GGVCCSYGPWGEFREGWHVQRPWQLAQELEPQSWC---CRWND------KPYLCALYQQR 431
G C G G H R + L Q P C CR + +P C ++
Sbjct: 2381 GDTCVPVGQCGCL----HDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETC 2436
Query: 432 RPH---VGCATYRPPQPAWMFGDPHITTLDGVSYTFNGLGDFLLV---GAQDGNSSFLLQ 485
RP +GC GDPH TT DG + F G ++L G + G F +
Sbjct: 2437 RPSGGSLGCVAVGSTT-CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVL 2495
Query: 486 GRTAQTGSAQATNFIAFAAQYRSSSLGPVTVQWLLEPHDA---IRVLLDNQTVTFQPDHE 542
G+ + + Q + +L QW + + + V+L N
Sbjct: 2496 QENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLAN---------- 2545
Query: 543 DGGGQETFNATGVLLSRNGSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLG 602
GQ + S++GS+V D V A + + ++P Y GL G
Sbjct: 2546 ---GQ-------IRASQHGSDVVIETDFGLRV---AYDLVYYVRVTVPGNYYQLMCGLCG 2592
Query: 603 VWNNNPEDDFRMPNGSTIPPGSPEEMLFHFGMTWQ 637
+N +P+DDF+ PNGS G+ E FG +W+
Sbjct: 2593 NYNGDPKDDFQKPNGS--QAGNANE----FGNSWE 2621
Score = 52.8 bits (125), Expect = 2e-06
Identities = 68/275 (24%), Positives = 103/275 (37%), Gaps = 52/275 (18%)
Query: 381 GGVCCSYGPWGEFREGWHVQRPWQLAQELEPQSWC---CRWND------KPYLCALYQQR 431
G C G G H R + L Q P C CR + +P C ++
Sbjct: 3582 GDTCVPVGQCGCL----HDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETC 3637
Query: 432 RPH---VGCATYRPPQPAWMFGDPHITTLDGVSYTFNGLGDFLLV---GAQDGNSSFLLQ 485
RP +GC GDPH TT DG + F G ++L G + G F +
Sbjct: 3638 RPSGGSLGCVAVGSTT-CQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVL 3696
Query: 486 GRTAQTGSAQATNFIAFAAQYRSSSLGPVTVQWLLEPHDA---IRVLLDNQTVTFQPDHE 542
G+ + + Q + +L QW + + + V+L N
Sbjct: 3697 QENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLAN---------- 3746
Query: 543 DGGGQETFNATGVLLSRNGSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLG 602
GQ + S++GS+V D V A + + ++P Y GL G
Sbjct: 3747 ---GQ-------IRASQHGSDVVIETDFGLRV---AYDLVYYVRVTVPGNYYQLMCGLCG 3793
Query: 603 VWNNNPEDDFRMPNGSTIPPGSPEEMLFHFGMTWQ 637
+N +P+DDF+ PNGS G+ E FG +W+
Sbjct: 3794 NYNGDPKDDFQKPNGS--QAGNANE----FGNSWE 3822
Score = 50.4 bits (119), Expect = 1e-05
Identities = 50/194 (25%), Positives = 80/194 (41%), Gaps = 35/194 (18%)
Query: 450 GDPHITTLDGVSYTFNGLGDFLLV---GAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQY 506
GDPH TT DG + F G ++L G + G F + G+ + + Q
Sbjct: 1256 GDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQV 1315
Query: 507 RSSSLGPVTVQWLLEPHDA---IRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRNGSE 563
+ +L QW + + + V+L N GQ + S++GS+
Sbjct: 1316 ANFTLRLEQRQWKVTVNGVDMKLPVVLAN-------------GQ-------IRASQHGSD 1355
Query: 564 VSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIPPG 623
V D V A + + ++P Y + GL G +N +P+DDF+ PNGS G
Sbjct: 1356 VVIETDFGLRV---AYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGS--QAG 1410
Query: 624 SPEEMLFHFGMTWQ 637
+ E FG +W+
Sbjct: 1411 NANE----FGNSWE 1420
Score = 45.4 bits (106), Expect = 3e-04
Identities = 50/198 (25%), Positives = 74/198 (37%), Gaps = 38/198 (19%)
Query: 450 GDPHITTLDGVSYTFNGLGDFLLV---GAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQY 506
GDPH TT DG Y G + +V D +F ++ + GS
Sbjct: 476 GDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSR------------ 523
Query: 507 RSSSLGPVTVQWLLEPHDAIR-----VLLDNQTVTFQPDHEDGGGQETFNATGVLLSRNG 561
R S +G VTV+ R VL+DNQ +G V S
Sbjct: 524 RVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG-------RLRVYQSGPR 576
Query: 562 SEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIP 621
+ V F V+ + SLP +Q++ GL G +N +P DDF P+G+ P
Sbjct: 577 AVVELVFG-----LVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAP 631
Query: 622 PGSPEEMLFHFGMTWQIN 639
F +W+++
Sbjct: 632 DA------VEFASSWKLD 643
Score = 44.7 bits (104), Expect = 5e-04
Identities = 49/196 (25%), Positives = 78/196 (39%), Gaps = 23/196 (11%)
Query: 447 WMFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQY 506
W++GDPH + DG + F G +++L A G QG T T + + N A Y
Sbjct: 1674 WLWGDPHYHSFDGRKFDFQGTCNYVL--ATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSY 1731
Query: 507 -RSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRN-GSEV 564
R ++ + + + +V ++ DG T A+ LL + G +V
Sbjct: 1732 VRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQV 1791
Query: 565 SASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIPPGS 624
S ++ W +LP Y GL G + NP +D PNG T+ P
Sbjct: 1792 SYDWN-W------------RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG-TLAPSI 1837
Query: 625 PEEMLFHFGMTWQING 640
P +G +W+ G
Sbjct: 1838 P-----IWGGSWRAPG 1848
Score = 44.7 bits (104), Expect = 5e-04
Identities = 49/196 (25%), Positives = 78/196 (39%), Gaps = 23/196 (11%)
Query: 447 WMFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQY 506
W++GDPH + DG + F G +++L A G QG T T + + N A Y
Sbjct: 2875 WLWGDPHYHSFDGRKFDFQGTCNYVL--ATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSY 2932
Query: 507 -RSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRN-GSEV 564
R ++ + + + +V ++ DG T A+ LL + G +V
Sbjct: 2933 VRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQV 2992
Query: 565 SASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIPPGS 624
S ++ W +LP Y GL G + NP +D PNG T+ P
Sbjct: 2993 SYDWN-W------------RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG-TLAPSI 3038
Query: 625 PEEMLFHFGMTWQING 640
P +G +W+ G
Sbjct: 3039 P-----IWGGSWRAPG 3049
Score = 42.7 bits (99), Expect = 0.002
Identities = 48/196 (24%), Positives = 77/196 (39%), Gaps = 23/196 (11%)
Query: 447 WMFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQY 506
W++GDPH + DG + F G +++L A G QG T T + + N A Y
Sbjct: 4076 WLWGDPHYHSFDGRKFDFQGTCNYVL--ATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSY 4133
Query: 507 -RSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRN-GSEV 564
R ++ + + + +V ++ DG A+ LL + G +V
Sbjct: 4134 VRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQV 4193
Query: 565 SASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIPPGS 624
S ++ W +LP Y GL G + NP +D PNG T+ P
Sbjct: 4194 SYDWN-W------------RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG-TLAPSI 4239
Query: 625 PEEMLFHFGMTWQING 640
P +G +W+ G
Sbjct: 4240 P-----IWGGSWRAPG 4250
Score = 42.0 bits (97), Expect = 0.003
Identities = 45/188 (23%), Positives = 76/188 (40%), Gaps = 22/188 (11%)
Query: 450 GDPHITTLDGVSYTFNGLGDFLLVGAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQYRSS 509
GDPH + DG + F G +LLVG+ G ++ L R + + +++ R
Sbjct: 868 GDPHYVSFDGRRFDFMGTCTYLLVGS-CGQNAALPAFRVLVENEHRGSQTVSYTRAVRVE 926
Query: 510 SLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRNGSEVSASFD 569
+ G V+ + +VL+D+ + + P G + F + R ++ ++D
Sbjct: 927 ARG---VKVAVRREYPGQVLVDD-VLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYD 982
Query: 570 GWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIPPGSPEEML 629
A V +A +P Y GL G +N +P DD + G G L
Sbjct: 983 WNARV-----------TAKVPSSYAEALCGLCGNFNGDPADDLALRGG-----GQAANAL 1026
Query: 630 FHFGMTWQ 637
FG +WQ
Sbjct: 1027 -AFGNSWQ 1033
Score = 42.0 bits (97), Expect = 0.003
Identities = 55/218 (25%), Positives = 81/218 (37%), Gaps = 43/218 (19%)
Query: 446 AWMFGDPHITTLDGVSYTFNGLGDFLLV----GAQDGNSSFLLQGRTAQTGSAQATNFIA 501
AW GDPH TLDG + F G ++LL G G +F + GS + +
Sbjct: 2074 AW--GDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 2131
Query: 502 FAAQYRSSSLGPVTVQWLLEPH-DAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRN 560
Q + SL ++ +W + D + V L Q + H G +G
Sbjct: 2132 VTLQIYNHSL-TLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSG------ 2184
Query: 561 GSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTI 620
+S +FDG + V + +P Y GL G +N +P DD + G
Sbjct: 2185 ---LSLAFDGDSFVRL-----------RVPAAYAGSLCGLCGNYNQDPADDLKAVGGK-- 2228
Query: 621 PPGSPEEMLFHFGMTWQINGTGLLGK-RNDQLPSNFTP 657
P G WQ+ G G+ + PS TP
Sbjct: 2229 PAG------------WQVGGAQGCGECVSKPCPSPCTP 2254
Score = 41.6 bits (96), Expect = 0.004
Identities = 55/218 (25%), Positives = 81/218 (37%), Gaps = 43/218 (19%)
Query: 446 AWMFGDPHITTLDGVSYTFNGLGDFLLV----GAQDGNSSFLLQGRTAQTGSAQATNFIA 501
AW GDPH TLDG + F G ++LL G G +F + GS + +
Sbjct: 3275 AW--GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 3332
Query: 502 FAAQYRSSSLGPVTVQWLLEPH-DAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRN 560
Q + SL ++ +W + D + V L Q + H G +G
Sbjct: 3333 VTLQIYNHSL-TLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSG------ 3385
Query: 561 GSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTI 620
+S +FDG + V + +P Y GL G +N +P DD + G
Sbjct: 3386 ---LSLAFDGDSFVRL-----------RVPAAYAGSLCGLCGNYNQDPADDLKAVGGK-- 3429
Query: 621 PPGSPEEMLFHFGMTWQINGTGLLGK-RNDQLPSNFTP 657
P G WQ+ G G+ + PS TP
Sbjct: 3430 PAG------------WQVGGAQGCGECVSKPCPSPCTP 3455
Score = 40.8 bits (94), Expect = 0.008
Identities = 55/218 (25%), Positives = 81/218 (37%), Gaps = 43/218 (19%)
Query: 446 AWMFGDPHITTLDGVSYTFNGLGDFLLV----GAQDGNSSFLLQGRTAQTGSAQATNFIA 501
AW GDPH TLDG + F G ++LL G G +F + GS + +
Sbjct: 4476 AW--GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 4533
Query: 502 FAAQYRSSSLGPVTVQWLLEPH-DAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRN 560
Q + SL ++ +W + D + V L Q + H G +G
Sbjct: 4534 VTLQIYNHSL-TLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSG------ 4586
Query: 561 GSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTI 620
+S +FDG + V + +P Y GL G +N +P DD + G
Sbjct: 4587 ---LSLAFDGDSFVRL-----------RVPAAYAASLCGLCGNYNQDPADDLKAVGGK-- 4630
Query: 621 PPGSPEEMLFHFGMTWQINGTGLLGK-RNDQLPSNFTP 657
P G WQ+ G G+ + PS TP
Sbjct: 4631 PAG------------WQVGGAQGCGECVSKPCPSPCTP 4656
Score = 37.0 bits (84), Expect = 0.11
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 6/58 (10%)
Query: 584 HASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIPPGSPEEMLFHFGMTWQINGT 641
H S+P ++ R GL G +N N DDF +PNGS + FG W+ G+
Sbjct: 4969 HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSA------ASSVETFGAAWRAPGS 5020
Score = 30.8 bits (68), Expect = 7.9
Identities = 24/76 (31%), Positives = 26/76 (34%), Gaps = 19/76 (25%)
Query: 821 VAGCKCDGGTF------------------GRYCE-GSEDACEEPCFPSVHCVPGKGCEAC 861
V GC+CD G G Y E GSE + C C PG G C
Sbjct: 1984 VEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC 2043
Query: 862 PPNLTGDGRHCAALGS 877
P G G C L S
Sbjct: 2044 TPASCGLGEVCGLLPS 2059
Score = 30.8 bits (68), Expect = 7.9
Identities = 24/76 (31%), Positives = 26/76 (34%), Gaps = 19/76 (25%)
Query: 821 VAGCKCDGGTF------------------GRYCE-GSEDACEEPCFPSVHCVPGKGCEAC 861
V GC+CD G G Y E GSE + C C PG G C
Sbjct: 3185 VEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC 3244
Query: 862 PPNLTGDGRHCAALGS 877
P G G C L S
Sbjct: 3245 TPASCGLGEVCGLLPS 3260
Score = 30.8 bits (68), Expect = 7.9
Identities = 24/76 (31%), Positives = 26/76 (34%), Gaps = 19/76 (25%)
Query: 821 VAGCKCDGGTF------------------GRYCE-GSEDACEEPCFPSVHCVPGKGCEAC 861
V GC+CD G G Y E GSE + C C PG G C
Sbjct: 4386 VEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC 4445
Query: 862 PPNLTGDGRHCAALGS 877
P G G C L S
Sbjct: 4446 TPASCGLGEVCGLLPS 4461
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 52.4 bits (124), Expect = 3e-06
Identities = 37/104 (35%), Positives = 45/104 (43%), Gaps = 20/104 (19%)
Query: 835 CEGSEDACEEPCFPSVHCV--PGKG-CEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYC 891
CE + C P V CV PG C+ACPP GDGR C L S C
Sbjct: 309 CEINNGGCSVA--PPVECVNTPGSSHCQACPPGYQGDGRVCT------LTDICSVSNGGC 360
Query: 892 YNQGHCYISQTLGCQPMCTCPPAFTDSRCFLAGNNFSPTVNLEL 935
+ C S TLG P+CTC P +T GN + P ++L
Sbjct: 361 HPDASC--SSTLGSLPLCTCLPGYT-------GNGYGPNGCVQL 395
Score = 31.6 bits (70), Expect = 4.7
Identities = 19/60 (31%), Positives = 22/60 (36%), Gaps = 10/60 (16%)
Query: 824 CKCDGGTFGRYC-EGSEDACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQ 882
CKCD G G C E + PC CV G +C C L + LCQ
Sbjct: 418 CKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSC---------ECTRLWTGALCQ 468
>gi|61743978 stabilin 1 precursor [Homo sapiens]
Length = 2570
Score = 51.2 bits (121), Expect = 6e-06
Identities = 43/148 (29%), Positives = 52/148 (35%), Gaps = 27/148 (18%)
Query: 777 EILARSAKIGLA------SALQPRTVVCHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGT 830
+ L RS G A A P C C +C +G S C CD G
Sbjct: 1994 QCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRC----DEGLGGSG----SCFCDEGW 2045
Query: 831 FGRYCEGS---EDACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQNQSCP 887
G CE + C PC P C G CE C GDGR C + LCQ+
Sbjct: 2046 TGPRCEVQLELQPVCTPPCAPEAVCRAGNSCE-CSLGYEGDGRVCTV---ADLCQDGH-- 2099
Query: 888 VNYCYNQGHCYISQTLGCQPMCTCPPAF 915
C +C +G CTC P +
Sbjct: 2100 -GGCSEHANC---SQVGTMVTCTCLPDY 2123
Score = 38.1 bits (87), Expect = 0.050
Identities = 41/167 (24%), Positives = 56/167 (33%), Gaps = 54/167 (32%)
Query: 793 PRTVVCHCNAESQCLYNQTSRVGNSSLEVAGCKC-DGGTFGRYCEGSEDACEEP----CF 847
P + HC+ ++C+ S VA C+C DG + + C P C
Sbjct: 824 PTGLAQHCHLHARCV---------SQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCS 874
Query: 848 PSVHCVPGK----GCEACPPNLTGDGRHCAALGSSFLCQNQSC----------------- 886
+ CVPG C C +GDGR C A+ L C
Sbjct: 875 ENAECVPGSLGTHHC-TCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCT 933
Query: 887 -------------PVNYCY-NQGHCYISQTL----GCQPMCTCPPAF 915
P++ C G C+ T G Q +CTCPP F
Sbjct: 934 CKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
Score = 33.1 bits (74), Expect = 1.6
Identities = 41/132 (31%), Positives = 49/132 (37%), Gaps = 35/132 (26%)
Query: 799 HCNAESQ-CLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEEPCFPS-----VHC 852
HC+ E C + + S E C+C G +GSE PC+PS C
Sbjct: 191 HCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQ---QGSECRAPNPCWPSPCSLLAQC 247
Query: 853 -VPGKG---CEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCY-NQGHCYISQTLGC-- 905
V KG C CP N GDG C P + C N G C + TL C
Sbjct: 248 SVSPKGQAQCH-CPENYHGDGMVC-------------LPKDPCTDNLGGCPSNSTL-CVY 292
Query: 906 ----QPMCTCPP 913
Q CTC P
Sbjct: 293 QKPGQAFCTCRP 304
>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
sapiens]
Length = 3003
Score = 50.4 bits (119), Expect = 1e-05
Identities = 50/194 (25%), Positives = 80/194 (41%), Gaps = 35/194 (18%)
Query: 450 GDPHITTLDGVSYTFNGLGDFLLV---GAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQY 506
GDPH TT DG + F G ++L G + G F + G+ + + Q
Sbjct: 1256 GDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQV 1315
Query: 507 RSSSLGPVTVQWLLEPHDA---IRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRNGSE 563
+ +L QW + + + V+L N GQ + S++GS+
Sbjct: 1316 ANFTLRLEQRQWKVTVNGVDMKLPVVLAN-------------GQ-------IRASQHGSD 1355
Query: 564 VSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIPPG 623
V D V A + + ++P Y + GL G +N +P+DDF+ PNGS G
Sbjct: 1356 VVIETDFGLRV---AYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGS--QAG 1410
Query: 624 SPEEMLFHFGMTWQ 637
+ E FG +W+
Sbjct: 1411 NANE----FGNSWE 1420
Score = 45.4 bits (106), Expect = 3e-04
Identities = 50/198 (25%), Positives = 74/198 (37%), Gaps = 38/198 (19%)
Query: 450 GDPHITTLDGVSYTFNGLGDFLLV---GAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQY 506
GDPH TT DG Y G + +V D +F ++ + GS
Sbjct: 476 GDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSR------------ 523
Query: 507 RSSSLGPVTVQWLLEPHDAIR-----VLLDNQTVTFQPDHEDGGGQETFNATGVLLSRNG 561
R S +G VTV+ R VL+DNQ +G V S
Sbjct: 524 RVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG-------RLRVYQSGPR 576
Query: 562 SEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIP 621
+ V F V+ + SLP +Q++ GL G +N +P DDF P+G+ P
Sbjct: 577 AVVELVFG-----LVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAP 631
Query: 622 PGSPEEMLFHFGMTWQIN 639
F +W+++
Sbjct: 632 DA------VEFASSWKLD 643
Score = 43.5 bits (101), Expect = 0.001
Identities = 48/199 (24%), Positives = 79/199 (39%), Gaps = 27/199 (13%)
Query: 447 WMFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNSSFLLQGRTAQTGSAQATN----FIAF 502
W++GDPH + DG + F G +++L A G QG T T + + N +++
Sbjct: 1674 WLWGDPHYHSFDGRKFDFQGTCNYVL--ATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSY 1731
Query: 503 AAQYRSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRN-G 561
++LG + + +RV ++ DG A+ LL + G
Sbjct: 1732 VRVVTVAALG-TNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFG 1790
Query: 562 SEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIP 621
+VS ++ W +LP Y GL G + NP +D PNG T+
Sbjct: 1791 LQVSYDWN-W------------RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG-TLA 1836
Query: 622 PGSPEEMLFHFGMTWQING 640
P P +G +W+ G
Sbjct: 1837 PSIP-----IWGGSWRAPG 1850
Score = 42.0 bits (97), Expect = 0.003
Identities = 45/188 (23%), Positives = 76/188 (40%), Gaps = 22/188 (11%)
Query: 450 GDPHITTLDGVSYTFNGLGDFLLVGAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQYRSS 509
GDPH + DG + F G +LLVG+ G ++ L R + + +++ R
Sbjct: 868 GDPHYVSFDGRRFDFMGTCTYLLVGS-CGQNAALPAFRVLVENEHRGSQTVSYTRAVRVE 926
Query: 510 SLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRNGSEVSASFD 569
+ G V+ + +VL+D+ + + P G + F + R ++ ++D
Sbjct: 927 ARG---VKVAVRREYPGQVLVDD-VLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYD 982
Query: 570 GWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIPPGSPEEML 629
A V +A +P Y GL G +N +P DD + G G L
Sbjct: 983 WNARV-----------TAKVPSSYAEALCGLCGNFNGDPADDLALRGG-----GQAANAL 1026
Query: 630 FHFGMTWQ 637
FG +WQ
Sbjct: 1027 -AFGNSWQ 1033
Score = 40.8 bits (94), Expect = 0.008
Identities = 55/218 (25%), Positives = 81/218 (37%), Gaps = 43/218 (19%)
Query: 446 AWMFGDPHITTLDGVSYTFNGLGDFLLV----GAQDGNSSFLLQGRTAQTGSAQATNFIA 501
AW GDPH TLDG + F G ++LL G G +F + GS + +
Sbjct: 2076 AW--GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 2133
Query: 502 FAAQYRSSSLGPVTVQWLLEPH-DAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRN 560
Q + SL ++ +W + D + V L Q + H G +G
Sbjct: 2134 VTLQIYNHSL-TLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSG------ 2186
Query: 561 GSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTI 620
+S +FDG + V + +P Y GL G +N +P DD + G
Sbjct: 2187 ---LSLAFDGDSFVRL-----------RVPAAYAASLCGLCGNYNQDPADDLKAVGGK-- 2230
Query: 621 PPGSPEEMLFHFGMTWQINGTGLLGK-RNDQLPSNFTP 657
P G WQ+ G G+ + PS TP
Sbjct: 2231 PAG------------WQVGGAQGCGECVSKPCPSPCTP 2256
Score = 37.0 bits (84), Expect = 0.11
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 6/58 (10%)
Query: 584 HASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIPPGSPEEMLFHFGMTWQINGT 641
H S+P ++ R GL G +N N DDF +PNGS + FG W+ G+
Sbjct: 2569 HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSA------ASSVETFGAAWRAPGS 2620
Score = 30.8 bits (68), Expect = 7.9
Identities = 24/76 (31%), Positives = 26/76 (34%), Gaps = 19/76 (25%)
Query: 821 VAGCKCDGGTF------------------GRYCE-GSEDACEEPCFPSVHCVPGKGCEAC 861
V GC+CD G G Y E GSE + C C PG G C
Sbjct: 1986 VEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC 2045
Query: 862 PPNLTGDGRHCAALGS 877
P G G C L S
Sbjct: 2046 TPASCGLGEVCGLLPS 2061
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 49.7 bits (117), Expect = 2e-05
Identities = 32/101 (31%), Positives = 37/101 (36%), Gaps = 10/101 (9%)
Query: 824 CKCDGGTFGRYCEGSEDAC-EEPCFPSVHCVP---GKGCEACPPNLTGDGRHCAALGSSF 879
C+C G G+ CE D C C CV G C CP +G C
Sbjct: 1060 CECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTC-TCPQGFSGP--FCEHPPPMV 1116
Query: 880 LCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
L Q C C N C + Q +P C CPP F RC
Sbjct: 1117 LLQTSPCDQYECQNGAQCIVVQQ---EPTCRCPPGFAGPRC 1154
Score = 44.3 bits (103), Expect = 7e-04
Identities = 40/161 (24%), Positives = 57/161 (35%), Gaps = 39/161 (24%)
Query: 795 TVVCHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEE-PCFPSVHCV 853
TV + ++ C + T + +S + C C G G+ CE + D CE+ C + CV
Sbjct: 953 TVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCV 1012
Query: 854 PGKG---CEACPPNLTGD------------------GRHCAALGSSFLCQ---------- 882
G C CPPN TG+ C L F C+
Sbjct: 1013 DGINNYVC-ICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLC 1071
Query: 883 ---NQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
N C + C + C + G CTCP F+ C
Sbjct: 1072 ETDNDDCVAHKCRHGAQC-VDTINGY--TCTCPQGFSGPFC 1109
Score = 37.7 bits (86), Expect = 0.065
Identities = 29/101 (28%), Positives = 38/101 (37%), Gaps = 14/101 (13%)
Query: 824 CKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQN 883
C+C G G C+ +PC C GK C T CA LC N
Sbjct: 1353 CECRPGWTGPLCD---QEARDPCLGH-RCHHGK----CVATGTSYMCKCAEGYGGDLCDN 1404
Query: 884 QSCPVNYCY----NQGHCYISQTLGCQPMCTCPPAFTDSRC 920
++ N C + G C+IS +P C C P F+ C
Sbjct: 1405 KNDSANACSAFKCHHGQCHISDQ--GEPYCLCQPGFSGEHC 1443
Score = 34.3 bits (77), Expect = 0.72
Identities = 38/147 (25%), Positives = 52/147 (35%), Gaps = 24/147 (16%)
Query: 796 VVCHCNA--ESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDAC-EEPCFPSVHC 852
+V CNA S C N T +E+ C C G+ C + C + PC C
Sbjct: 913 IVAKCNACLSSPCKNNGTCT--QDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTC 970
Query: 853 ------VPGKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQ 906
G C +CP L +G+ C C N C N C
Sbjct: 971 HLSDSHKDGFSC-SCP--LGFEGQRCEI-------NPDDCEDNDCENNATCVDGIN---N 1017
Query: 907 PMCTCPPAFTDSRCFLAGNNFSPTVNL 933
+C CPP +T C ++ P +NL
Sbjct: 1018 YVCICPPNYTGELCDEVIDHCVPELNL 1044
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 49.7 bits (117), Expect = 2e-05
Identities = 114/501 (22%), Positives = 166/501 (33%), Gaps = 84/501 (16%)
Query: 450 GDPHITTLDGVSYTFNGLGDFLLVGAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQYRSS 509
G PH T DG+++T+ G ++LLV ++ + F + + G++ T A A +
Sbjct: 1018 GAPHYVTFDGLAFTYPGACEYLLV--REASGLFTVSAQNLPCGASGLTCTKALAVRLEG- 1074
Query: 510 SLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRNGSEVSASFD 569
TV +L R + N P G G A LL ++ +D
Sbjct: 1075 -----TVVHMLRG----RAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWD 1125
Query: 570 GWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIP-------- 621
G V V L P+++ R GL G ++ + +D R G P
Sbjct: 1126 GGTRVLV-----------QLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHS 1174
Query: 622 ----PGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVFYSQL--QKNSSWAEHLIS 675
P PE T + G R L + ++++ Q++ W +
Sbjct: 1175 WRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDAC 1234
Query: 676 NCD--GDSSCIYDTLALRNASIGLHTREVSKNYEQANATLNQYPPSINGGRVIEAYKGQT 733
CD GD C+ +A H V ++ + GG+V EA
Sbjct: 1235 GCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSL------QCEGGQVYEACGPTC 1288
Query: 734 TLIQYTSNAEDANFTLRDSCTDLELFENGTLLWTPKSLEPFTLEILARSAKIGLASALQP 793
+ + E +C + GTLL LEP + S LQ
Sbjct: 1289 PPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQK 1348
Query: 794 RTVVCHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEEP---CFPSV 850
C C E Q C DGG +CE AC E C +
Sbjct: 1349 DCGNCTCQ-EGQW----------------HCGGDGG----HCEELVPACAEGEALCQENG 1387
Query: 851 HCVPGKGCEACPPNLTGDG---RHCAALG---SSFLCQNQSC-PVN-YCYNQGHCYISQT 902
HCVP G + GDG CAA G C + C P+ C Q C
Sbjct: 1388 HCVP-HGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDDCGDGTD 1446
Query: 903 LGCQPMCTCPP---AFTDSRC 920
+P CP A D RC
Sbjct: 1447 ---EPSYPCPQGLLACADGRC 1464
Score = 41.6 bits (96), Expect = 0.004
Identities = 53/215 (24%), Positives = 80/215 (37%), Gaps = 46/215 (21%)
Query: 429 QQRRPHVGCATYRPPQPAWMFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNSSFLLQ--G 486
Q +RP CA++ H T DG Y F G +LL GA D + L
Sbjct: 187 QHQRPSATCASW---------SGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGD 237
Query: 487 RTAQTGSAQATNFIAFAAQYRSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGG 546
R Q G Q + + G V+V+ L P + LL ++ + D
Sbjct: 238 RCPQPGHCQR---VTMGPEEVLIQAGNVSVKGQLVP-EGQSWLLHGLSLQWLGDW----- 288
Query: 547 QETFNATGVLLSRNGSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNN 606
L+ G V D ++S+ S+ E +T+GL G++N
Sbjct: 289 ---------LVLSGGLGVVVRLDRTGSISI-----------SVDHELWGQTQGLCGLYNG 328
Query: 607 NPEDDFRMPNGSTIPPGSPEEMLFHFGMTWQINGT 641
PEDDF P G + FG +W++ G+
Sbjct: 329 WPEDDFMEPGGGL------AMLAATFGNSWRLPGS 357
Score = 39.3 bits (90), Expect = 0.022
Identities = 51/223 (22%), Positives = 80/223 (35%), Gaps = 34/223 (15%)
Query: 437 CATYRPPQPAWMFGDPHITTLDGVSYTFNGLGDFLLVGAQD---GNSSFLLQGRTAQTGS 493
CA P + GD H T DG SY+F G QD G LL+ GS
Sbjct: 555 CAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILLEHGACDAGS 614
Query: 494 AQATNFIAFAAQYRSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNAT 553
++ + ++ D+ VL++ Q V +G ++
Sbjct: 615 CLHAISVSLEDTH-------------IQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSA 661
Query: 554 GVLLSRNGSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFR 613
+LL G++V W +A +L P + ++ +GL G + N +DDF
Sbjct: 662 FLLLRWPGAQVL-----WGLSDPVAY-------ITLDPRHAHQVQGLCGTFTQNQQDDF- 708
Query: 614 MPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFT 656
P G E + F +Q+ G G + L S T
Sbjct: 709 -----LTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCT 746
Score = 32.7 bits (73), Expect = 2.1
Identities = 29/94 (30%), Positives = 34/94 (36%), Gaps = 15/94 (15%)
Query: 826 CDGG--TFGRYCEG---SEDACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFL 880
CDGG T GR C + C P + C CP N+ S+
Sbjct: 2846 CDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENML--------FRSAEQ 2897
Query: 881 CQNQSCPV-NYCYNQGHCYISQTLGCQPMCTCPP 913
C + P C QG I T C P CTCPP
Sbjct: 2898 CHQEGGPCPRLCLTQGPG-IECTGFCAPGCTCPP 2930
Score = 32.0 bits (71), Expect = 3.6
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 16/79 (20%)
Query: 836 EGSEDACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAAL-GSSFLCQNQSCPVNYCYNQ 894
+G D CE P G+ C+A P +T +C A+ G+ + CP + C +
Sbjct: 3285 QGLGDYCEGPR------AQGEVCQALPCPVT----NCTAIEGAEYSPCGPPCPRS-CDDL 3333
Query: 895 GHCYISQTLGCQPMCTCPP 913
HC CQP C CPP
Sbjct: 3334 VHC----VWRCQPGCYCPP 3348
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 47.8 bits (112), Expect = 6e-05
Identities = 35/130 (26%), Positives = 46/130 (35%), Gaps = 36/130 (27%)
Query: 824 CKCDGGTFGRYCEGSEDACEE-PCFPSVHC---------------VPGKGCEA----CPP 863
C C G +G+ CE S C + PCF C G CE C
Sbjct: 352 CTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSS 411
Query: 864 NLTGDGRHCAALGSSFLCQNQS-------------CPVNYCYNQGHCYISQTLGCQPMCT 910
+ +G C LG ++LC+ Q+ C + C N G C CT
Sbjct: 412 SPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVN---DFSCT 468
Query: 911 CPPAFTDSRC 920
CPP +T C
Sbjct: 469 CPPGYTGRNC 478
Score = 44.3 bits (103), Expect = 7e-04
Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 19/102 (18%)
Query: 824 CKCDGGTFGRYCEGSEDAC-EEPCFPSVHCVPGK---GCEACPPNLTGDGRHCAALGSSF 879
C+C G GR+C+ + D C PC C G C CPP T GR+C+A S
Sbjct: 429 CRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSC-TCPPGYT--GRNCSAPVSR- 484
Query: 880 LCQNQSCPVN-YCYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
C++ C C+ +GH Y+ C C + C
Sbjct: 485 -CEHAPCHNGATCHERGHRYV---------CECARGYGGPNC 516
Score = 34.3 bits (77), Expect = 0.72
Identities = 34/129 (26%), Positives = 44/129 (34%), Gaps = 34/129 (26%)
Query: 824 CKCDGGTFGRYCEGS-------EDACEEPCFPSVHCVPGKGCEACPPNLT--------GD 868
CKC G GRYC+ C++P +C G G C +L +
Sbjct: 243 CKCRVGWQGRYCDECIRYPGCLHGTCQQPW--QCNCQEGWGGLFCNQDLNYCTHHKPCKN 300
Query: 869 GRHCAALG-SSFLCQNQ-------------SCPVNYCYNQGHCYISQTLGCQPMCTCPPA 914
G C G S+ C + C + C N G C L CTCPP
Sbjct: 301 GATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSC---TDLENSYSCTCPPG 357
Query: 915 FTDSRCFLA 923
F C L+
Sbjct: 358 FYGKICELS 366
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 46.2 bits (108), Expect = 2e-04
Identities = 37/123 (30%), Positives = 46/123 (37%), Gaps = 22/123 (17%)
Query: 803 ESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACE-EPCFPSVHCVPGKGCE-- 859
ES C T G +S C C G G YC+ + C+ +PC C G G
Sbjct: 989 ESSCFNGGTCVDGINSFT---CLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRC 1045
Query: 860 ACPPNLTGDGRHCAALGSSFLCQN--QSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTD 917
CP TG CQN C + C N G C+ + T Q C CP +T
Sbjct: 1046 TCPQGYTGPN-----------CQNLVHWCDSSPCKNGGKCWQTHT---QYRCECPSGWTG 1091
Query: 918 SRC 920
C
Sbjct: 1092 LYC 1094
Score = 45.8 bits (107), Expect = 2e-04
Identities = 39/137 (28%), Positives = 49/137 (35%), Gaps = 25/137 (18%)
Query: 798 CHCNAE----------SQCLYNQTSRVGNSS--LEVAGCKCDGGTFGRYCEGSEDACEEP 845
CHC A C N G+ + + A C C G G +CE + C
Sbjct: 893 CHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECA-- 950
Query: 846 CFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQNQS--CPVNYCYNQGHCYISQTL 903
S C G C C + T C A S C+N + C + C+N G C
Sbjct: 951 ---SDPCRNGANCTDCVDSYTCT---CPAGFSGIHCENNTPDCTESSCFNGGTCVDGIN- 1003
Query: 904 GCQPMCTCPPAFTDSRC 920
C CPP FT S C
Sbjct: 1004 --SFTCLCPPGFTGSYC 1018
Score = 44.7 bits (104), Expect = 5e-04
Identities = 36/137 (26%), Positives = 47/137 (34%), Gaps = 43/137 (31%)
Query: 824 CKCDGGTFGRYCEGSEDACE-EPCFPSVHC---VPGKGC---------------EACPPN 864
C+C G G YCE D C PC C + G C + C +
Sbjct: 1131 CRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSH 1190
Query: 865 LTGDGRHCAALGSSFLC------QNQSCPVNY---------------CYNQGHCYISQTL 903
+G C L +++ C Q C +N C+N G C + Q
Sbjct: 1191 PCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTC-VDQVG 1249
Query: 904 GCQPMCTCPPAFTDSRC 920
G CTCPP F RC
Sbjct: 1250 GYS--CTCPPGFVGERC 1264
Score = 43.1 bits (100), Expect = 0.002
Identities = 37/144 (25%), Positives = 52/144 (36%), Gaps = 21/144 (14%)
Query: 806 CLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKGCEACPPNL 865
C T V +++ CKC G G CE C S+ C+ G C + P +
Sbjct: 1316 CKNGGTCAVASNTARGFICKCPAGFEGATCENDARTC-----GSLRCLNGGTCISGPRSP 1370
Query: 866 TGDGRHCAALG------SSFLCQNQSCPVNYCYNQGHCYISQTLGCQPM--CTCPPAFTD 917
T C LG F + N CYNQG C + P C CP F
Sbjct: 1371 T-----CLCLGPFTGPECQFPASSPCLGGNPCYNQGTC---EPTSESPFYRCLCPAKFNG 1422
Query: 918 SRCFLAGNNFSPTVNLELPLRVIQ 941
C + +F ++P +I+
Sbjct: 1423 LLCHILDYSFGGGAGRDIPPPLIE 1446
Score = 41.6 bits (96), Expect = 0.004
Identities = 37/168 (22%), Positives = 58/168 (34%), Gaps = 47/168 (27%)
Query: 799 HCNAESQCLYNQTSRVGNSSLEVAG---CKCDGGTFGRYCEGSEDACEEP---------C 846
+C+ E + + G + L++ C C GT G +CE + D C P C
Sbjct: 1179 NCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKC 1238
Query: 847 FPSVHCVP---GKGCEACPPNLTGD------------------GRHCAALGSSFLCQNQS 885
F + CV G C CPP G+ ++C + F C+ ++
Sbjct: 1239 FNNGTCVDQVGGYSC-TCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA 1297
Query: 886 -------------CPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
C C N G C ++ +C CP F + C
Sbjct: 1298 GHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATC 1345
Score = 39.7 bits (91), Expect = 0.017
Identities = 31/102 (30%), Positives = 38/102 (37%), Gaps = 18/102 (17%)
Query: 824 CKCDGGTFGRYC-EGSEDACEEPCFPSVHC---VPGKGCEACPPNLTGDGRHCAALGSSF 879
C C G G C E +D CF C V CE CP TG
Sbjct: 321 CVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCE-CPHGRTG-----------L 368
Query: 880 LCQ-NQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
LC N +C N C +C + G + +CTCP +T C
Sbjct: 369 LCHLNDACISNPCNEGSNCDTNPVNG-KAICTCPSGYTGPAC 409
Score = 36.6 bits (83), Expect = 0.14
Identities = 37/161 (22%), Positives = 51/161 (31%), Gaps = 40/161 (24%)
Query: 797 VCHCNAESQCLYNQTSRVGNSSLEVAG---CKCDGGTFGRYCEGSEDACEEPCFPSVHCV 853
+C ++ CL N G L C+C G G+ C+ ++ PC C+
Sbjct: 97 LCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCL 156
Query: 854 PGKG---CEACPPNLTGDG---------------RH--------------CAALGSSFLC 881
P + C CPP+ G RH C A + C
Sbjct: 157 PFEASYICH-CPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNC 215
Query: 882 QNQ--SCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
+ C + C N G C T C C P FT C
Sbjct: 216 ERPYVPCSPSPCQNGGTC--RPTGDVTHECACLPGFTGQNC 254
Score = 36.2 bits (82), Expect = 0.19
Identities = 29/104 (27%), Positives = 36/104 (34%), Gaps = 11/104 (10%)
Query: 818 SLEVAGCKCDGGTFGRYCEGSEDACE-EPCFPSVHCVPGKGCEACPPNLTGDGRHCAALG 876
SL C CD G G C+ + + CE PC C C G +C
Sbjct: 733 SLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQT-- 790
Query: 877 SSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
C N C NQG C I G + C C +T + C
Sbjct: 791 -----NINECASNPCLNQGTC-IDDVAGYK--CNCLLPYTGATC 826
Score = 35.4 bits (80), Expect = 0.32
Identities = 39/150 (26%), Positives = 52/150 (34%), Gaps = 22/150 (14%)
Query: 778 ILARSAKIGLASALQPRTVVCHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEG 837
+LA + L AL R C E+ CL N + C C G G C+
Sbjct: 4 LLAPLLCLALLPALAARGPRCSQPGET-CLNGGKCEAANGT---EACVCGGAFVGPRCQD 59
Query: 838 SEDACEEPC--FPSVHCVPGKGCE--ACPPNLTGDGRHCAALGSSFLC---QNQSCPVNY 890
PC + H V +G AC CA S LC + +C N
Sbjct: 60 PNPCLSTPCKNAGTCHVVDRRGVADYAC---------SCALGFSGPLCLTPLDNACLTNP 110
Query: 891 CYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
C N G C + + C CPP ++ C
Sbjct: 111 CRNGGTCDLLTL--TEYKCRCPPGWSGKSC 138
Score = 35.0 bits (79), Expect = 0.42
Identities = 28/120 (23%), Positives = 36/120 (30%), Gaps = 15/120 (12%)
Query: 802 AESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDAC-EEPCFPSVHCVPGKGCEA 860
A S CL+N + C+C G G C+ D C PC C+ G
Sbjct: 495 ASSPCLHNGRCL---DKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYT 551
Query: 861 CPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
C G HC C C C + + C C P +T C
Sbjct: 552 CVCTEGYTGTHCEV--DIDECDPDPCHYGSCKDGVATF---------TCLCRPGYTGHHC 600
Score = 35.0 bits (79), Expect = 0.42
Identities = 39/142 (27%), Positives = 48/142 (33%), Gaps = 21/142 (14%)
Query: 799 HCNAESQCLYNQTSRVGNSSLEVAG---CKCDGGTFGRYCEGSEDACEEPCFPSVHC--- 852
HC +Q R G + + C C GT G CE + D C S C
Sbjct: 599 HCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDK 658
Query: 853 VPGKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCP 912
+ G C AC P T GS C N C+N G C C CP
Sbjct: 659 IDGYEC-ACEPGYT---------GSMCNINIDECAGNPCHNGGTCEDGIN---GFTCRCP 705
Query: 913 PAFTDSRCFLAGN--NFSPTVN 932
+ D C N N +P V+
Sbjct: 706 EGYHDPTCLSEVNECNSNPCVH 727
Score = 33.5 bits (75), Expect = 1.2
Identities = 45/203 (22%), Positives = 60/203 (29%), Gaps = 26/203 (12%)
Query: 721 NGGRVIEAYKGQTTLIQYTSNAEDANFTLRDSCTDLELFENGTLLWTPKSLEPFTLEILA 780
NGG + G + ED + + D C F T + F E
Sbjct: 308 NGGTCHNTHGGYNCVCVNGWTGEDCSENI-DDCASAACFHGATC---HDRVASFYCE--C 361
Query: 781 RSAKIGLASALQPRTVVCHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSED 840
+ GL L + CN S C T+ V ++ C C G G C D
Sbjct: 362 PHGRTGLLCHLNDACISNPCNEGSNC---DTNPVNGKAI----CTCPSGYTGPACSQDVD 414
Query: 841 ACE---EPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHC 897
C PC + C+ G C G C C N C N C
Sbjct: 415 ECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCE-------IDVNECVSNPCQNDATC 467
Query: 898 YISQTLGCQPMCTCPPAFTDSRC 920
+G + C C P + C
Sbjct: 468 L--DQIG-EFQCICMPGYEGVHC 487
Score = 32.3 bits (72), Expect = 2.7
Identities = 22/61 (36%), Positives = 31/61 (50%), Gaps = 9/61 (14%)
Query: 1068 GYKGYDLVYSPQSGFTC---VSPCSRGYCDHGGQCQHLPSGPRCSCVSFSIYTAW-GEHC 1123
GYK L+ P +G TC ++PC+ C +GG+C+ SCV T W G+ C
Sbjct: 812 GYKCNCLL--PYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCV---CPTGWQGQTC 866
Query: 1124 E 1124
E
Sbjct: 867 E 867
Score = 31.6 bits (70), Expect = 4.7
Identities = 28/103 (27%), Positives = 34/103 (33%), Gaps = 21/103 (20%)
Query: 824 CKCDGGTFGRYCEGSEDAC-EEPCFPSVHCVPGKG---CEACPPNLTGDGRHCAALGSSF 879
C C G G +CE + D C PC + C+ CE CP TG
Sbjct: 476 CICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCE-CPTGFTG-----------H 523
Query: 880 LCQN--QSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
LCQ C C N C C C +T + C
Sbjct: 524 LCQYDVDECASTPCKNGAKCLDGPN---TYTCVCTEGYTGTHC 563
Score = 30.8 bits (68), Expect = 7.9
Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 23/105 (21%)
Query: 824 CKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKGCE--------ACPPNLTGDGRHCAAL 875
C C G G+ CE + D C P +C G C CPP T G++C
Sbjct: 243 CACLPGFTGQNCEENIDDC-----PGNNCKNGGACVDGVNTYNCRCPPEWT--GQYC--- 292
Query: 876 GSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
+ + + Q P N C N G C+ T G C C +T C
Sbjct: 293 -TEDVDECQLMP-NACQNGGTCH--NTHGGY-NCVCVNGWTGEDC 332
>gi|126012562 low density lipoprotein-related protein 1 [Homo sapiens]
Length = 4544
Score = 46.2 bits (108), Expect = 2e-04
Identities = 44/169 (26%), Positives = 56/169 (33%), Gaps = 35/169 (20%)
Query: 752 SCTDLELFENGTLLWTPKSLEPFTLEILARSAKIGLASALQPRTVVCHCNAESQCLYNQT 811
+C + + +NGT + P P A +P T C C N
Sbjct: 4170 TCPNGKRLDNGTCVPVPSPTPP--------------PDAPRPGTCNLQCFNGGSCFLNAR 4215
Query: 812 SRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKGCEACPPNLTGDGRH 871
+ C+C G CE D C E HC G C A P +
Sbjct: 4216 RQ--------PKCRCQPRYTGDKCE--LDQCWE------HCRNGGTCAASPSGMPTC--R 4257
Query: 872 CAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
C + C Q C YC N C ++Q G QP C C P F RC
Sbjct: 4258 CPTGFTGPKCTQQVC-AGYCANNSTCTVNQ--GNQPQCRCLPGFLGDRC 4303
Score = 34.3 bits (77), Expect = 0.72
Identities = 35/138 (25%), Positives = 45/138 (32%), Gaps = 20/138 (14%)
Query: 799 HCNAESQCLYNQTSRVGNSSLE-VAGCKCDGGTFGRYCEGSEDACEEPCFPSVHC----- 852
+C S C NQ ++ L G +C YCE C+ S C
Sbjct: 4275 YCANNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGYCENF-GTCQMAADGSRQCRCTAY 4333
Query: 853 VPGKGCE----------ACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQT 902
G CE AC N C +C V +C N G C ++
Sbjct: 4334 FEGSRCEVNKCSRCLEGACVVNKQSGDVTCNCTDGRVAPSCLTC-VGHCSNGGSCTMNSK 4392
Query: 903 LGCQPMCTCPPAFTDSRC 920
+ P C CPP T RC
Sbjct: 4393 M--MPECQCPPHMTGPRC 4408
Score = 32.0 bits (71), Expect = 3.6
Identities = 12/32 (37%), Positives = 18/32 (56%), Gaps = 2/32 (6%)
Query: 891 CYNQGHCYISQTLGCQPMCTCPPAFTDSRCFL 922
C+N G C+++ QP C C P +T +C L
Sbjct: 4204 CFNGGSCFLNARR--QPKCRCQPRYTGDKCEL 4233
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 46.2 bits (108), Expect = 2e-04
Identities = 51/178 (28%), Positives = 73/178 (41%), Gaps = 21/178 (11%)
Query: 448 MFGDPHITTLDGVSYTFNGLGDFLL---VGAQDGNSSFLLQGR--TAQTGSAQATNFIAF 502
M+G H +T DG SYTF G ++L + A+ GN S L TA +A A A
Sbjct: 5080 MWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAARCPRAL 5139
Query: 503 AAQYRSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRNGS 562
+ Y+S + V ++ + +L D V+ F+ GVL+S G+
Sbjct: 5140 SIHYKSMDI--VLTVTMVHGKEEGLILFDQIPVS-----------SGFSKNGVLVSVLGT 5186
Query: 563 EVSASFDGWATVSVIALSNILHASASLPPE-YQNRTEGLLGVWNNNPEDDFRMPNGST 619
VSV + A LP + N TEG G NN DD +G+T
Sbjct: 5187 TTMRVDIPALGVSVTFNGQVF--QARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTT 5242
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 45.8 bits (107), Expect = 2e-04
Identities = 43/140 (30%), Positives = 51/140 (36%), Gaps = 21/140 (15%)
Query: 799 HCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDAC-EEPCFPSVHCVP--- 854
+C CL T N+ + C C G G CE +E AC +PC C
Sbjct: 299 YCGTHQPCLNGGTC--SNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSL 356
Query: 855 GKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPA 914
G CE C P TG C+ C N C + G C Q L C CPP
Sbjct: 357 GFECE-CSPGWTGPT--CST-------NIDDCSPNNCSHGGTC---QDLVNGFKCVCPPQ 403
Query: 915 FTDSRCFLAGN--NFSPTVN 932
+T C L N P VN
Sbjct: 404 WTGKTCQLDANECEAKPCVN 423
Score = 43.1 bits (100), Expect = 0.002
Identities = 32/102 (31%), Positives = 39/102 (38%), Gaps = 16/102 (15%)
Query: 824 CKCDGGTFGRYCEGSEDACEEPCFPSVHC---VPGKGCEACPPNLTGDGRHCAALGSSFL 880
C C G G+ C+ + + C C C V G C CPP GD HC
Sbjct: 436 CDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRC-ICPPGYAGD--HCER------ 486
Query: 881 CQNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRCFL 922
C N C N GHC Q + C CP F+ + C L
Sbjct: 487 -DIDECASNPCLNGGHC---QNEINRFQCLCPTGFSGNLCQL 524
Score = 40.0 bits (92), Expect = 0.013
Identities = 34/135 (25%), Positives = 46/135 (34%), Gaps = 35/135 (25%)
Query: 824 CKCDGGTFGRYCEGSEDACE-EPCFPSVHCVPGKG--------------CEA----CPPN 864
C C+ G G YC + + CE PC C+ G CE C N
Sbjct: 615 CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQN 674
Query: 865 LTGDGRHCAALGSSFLC-------------QNQSCPVNYCYNQGHCYISQTLGCQPMCTC 911
+G C L + F C ++ C C N G CY G C C
Sbjct: 675 PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDE---GDAFKCMC 731
Query: 912 PPAFTDSRCFLAGNN 926
P + + C +A N+
Sbjct: 732 PGGWEGTTCNIARNS 746
Score = 39.3 bits (90), Expect = 0.022
Identities = 35/139 (25%), Positives = 47/139 (33%), Gaps = 36/139 (25%)
Query: 824 CKCDGGTFGRYCEGSEDACEE-PCFPSVHCVP--------------GKGCEA----CPPN 864
C C G G YCE + + C + PC C GK C + C
Sbjct: 653 CICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEA 712
Query: 865 LTGDGRHCAALGSSFLC--------------QNQSCPVNYCYNQGHCYISQTLGCQPMCT 910
+G C G +F C +N SC N C+N G C ++ G C
Sbjct: 713 TCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVN---GESFTCV 769
Query: 911 CPPAFTDSRCFLAGNNFSP 929
C + C N+ SP
Sbjct: 770 CKEGWEGPICAQNTNDCSP 788
Score = 38.1 bits (87), Expect = 0.050
Identities = 35/130 (26%), Positives = 48/130 (36%), Gaps = 21/130 (16%)
Query: 798 CHCNAESQCLYNQTSRVGNSSL--EVAGCKCDGGTFGRYC-EGSEDACEEPCFPSVHCVP 854
C+ S CL N G + E C C G G C + + D PC+ S CV
Sbjct: 740 CNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVD 799
Query: 855 GKG---CEACPPNLTGDGRHCAALGSSFLCQNQSCPVN-YCYNQGHCYISQTLGCQPMCT 910
G CE C P G C + CQ+ C C ++ + Y C
Sbjct: 800 GDNWYRCE-CAPGFAGP--DCRININE--CQSSPCAFGATCVDEINGY---------RCV 845
Query: 911 CPPAFTDSRC 920
CPP + ++C
Sbjct: 846 CPPGHSGAKC 855
Score = 35.8 bits (81), Expect = 0.25
Identities = 18/44 (40%), Positives = 24/44 (54%), Gaps = 4/44 (9%)
Query: 1071 GYDLVYSPQ-SGFTC---VSPCSRGYCDHGGQCQHLPSGPRCSC 1110
G++ SP +G TC + CS C HGG CQ L +G +C C
Sbjct: 357 GFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVC 400
Score = 32.3 bits (72), Expect = 2.7
Identities = 34/148 (22%), Positives = 46/148 (31%), Gaps = 30/148 (20%)
Query: 799 HCNAE-SQCLYNQTSRVGNSSLEVAG--CKCDGGTFGRYCEGSEDACE-EPCFPSVHCVP 854
HC + +C N G+ E+ C C G G C+ D CE PC C
Sbjct: 483 HCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYN 542
Query: 855 GKGCEACPPNLTGDGRHCAALGSSFLCQNQSCPV----------------------NYCY 892
C +G++C+ L C+ C V N C
Sbjct: 543 RASDYFCKCPEDYEGKNCSHLKDH--CRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCG 600
Query: 893 NQGHCYISQTLGCQPMCTCPPAFTDSRC 920
G C G + C C FT + C
Sbjct: 601 PHGKC--KSQSGGKFTCDCNKGFTGTYC 626
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 45.8 bits (107), Expect = 2e-04
Identities = 40/144 (27%), Positives = 52/144 (36%), Gaps = 38/144 (26%)
Query: 824 CKCDGGTFGRYC-EGSEDACEEPCFPSVHCV--------------PGKGCEACPPNLTGD 868
C CD G G YC E +D +PC C+ G+ C+ P + D
Sbjct: 584 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 643
Query: 869 GRH----CAALGSSFLC-------------QNQSCPVNYCYNQGHCYISQTLGCQPMCTC 911
H C L + F C + C C N G CY S G C C
Sbjct: 644 PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDS---GDTFRCAC 700
Query: 912 PPAFTDSRCFLAGNNF---SPTVN 932
PP + S C +A N+ +P VN
Sbjct: 701 PPGWKGSTCAVAKNSSCLPNPCVN 724
Score = 42.0 bits (97), Expect = 0.003
Identities = 37/130 (28%), Positives = 49/130 (37%), Gaps = 15/130 (11%)
Query: 799 HCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKGC 858
+C + C T N+ + C C G GR CE +E AC S C G C
Sbjct: 310 YCGSHHPCTNGGTCI--NAEPDQYRCTCPDGYSGRNCEKAEHAC-----TSNPCANGGSC 362
Query: 859 EACPPNLTGDGRHCAALGSSFLC--QNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFT 916
P +G HC + S C C N C G C + Q G + C CP +
Sbjct: 363 HEVP---SGFECHCPSGWSGPTCALDIDECASNPCAAGGTC-VDQVDGFE--CICPEQWV 416
Query: 917 DSRCFLAGNN 926
+ C L N+
Sbjct: 417 GATCQLDVND 426
Score = 39.3 bits (90), Expect = 0.022
Identities = 36/130 (27%), Positives = 45/130 (34%), Gaps = 36/130 (27%)
Query: 824 CKCDGGTFGRYCEGSEDACEE-------PCFPS-----VHCVPG-KGC-------EACPP 863
C CD G G+ C E C+ C+ S C PG KG +C P
Sbjct: 660 CACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLP 719
Query: 864 NLTGDGRHCAALGSSFLC------QNQSCPVNY-------CYNQGHCYISQTLGCQPMCT 910
N +G C G+SF C + ++C N CYN G C C
Sbjct: 720 NPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF---RCE 776
Query: 911 CPPAFTDSRC 920
C P F C
Sbjct: 777 CAPGFAGPDC 786
Score = 36.6 bits (83), Expect = 0.14
Identities = 31/99 (31%), Positives = 34/99 (34%), Gaps = 13/99 (13%)
Query: 824 CKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQ- 882
C C G GR+CE D C S C G CE G HC S LC+
Sbjct: 446 CVCPRGFGGRHCELERDEC-----ASSPCHSGGLCEDL---ADGFHCHCPQGFSGPLCEV 497
Query: 883 -NQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFTDSRC 920
C + C N CY L C CP F C
Sbjct: 498 DVDLCEPSPCRNGARCY---NLEGDYYCACPDDFGGKNC 533
Score = 35.8 bits (81), Expect = 0.25
Identities = 27/101 (26%), Positives = 36/101 (35%), Gaps = 22/101 (21%)
Query: 824 CKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQN 883
C+C G GR+C + C P CV G E N C LC
Sbjct: 262 CRCSYGWQGRFC--------DECVPYPGCVHGSCVEPWQCN-------CETNWGGLLCDK 306
Query: 884 QSCPVNYCYNQGHCYISQT-LGCQP---MCTCPPAFTDSRC 920
+NYC + C T + +P CTCP ++ C
Sbjct: 307 D---LNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNC 344
Score = 35.8 bits (81), Expect = 0.25
Identities = 23/62 (37%), Positives = 30/62 (48%), Gaps = 9/62 (14%)
Query: 1067 DGYKGYDLVYSPQ-SGFTC---VSPCSRGYCDHGGQCQHLPSGPRCSCVSFSIYTAWGEH 1122
D G++ + Q G TC V+ C RG C HGG C+ L +G +C C G H
Sbjct: 402 DQVDGFECICPEQWVGATCQLDVNDC-RGQCQHGGTCKDLVNGYQCVCPR----GFGGRH 456
Query: 1123 CE 1124
CE
Sbjct: 457 CE 458
Score = 33.9 bits (76), Expect = 0.94
Identities = 36/129 (27%), Positives = 45/129 (34%), Gaps = 19/129 (14%)
Query: 798 CHCNAESQCLYNQTSRVGN--SSLEVAGCKCDGGTFGRYCEGSEDACEE-PCFPSVHCVP 854
C S CL N G S C C G GR C + + C PC+ CV
Sbjct: 709 CAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVD 768
Query: 855 GKG---CEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTC 911
G CE C P G + + QS P Y G + + G + C+C
Sbjct: 769 GVNWFRCE-CAPGFAGPDCRIN------IDECQSSPCAY----GATCVDEINGYR--CSC 815
Query: 912 PPAFTDSRC 920
PP RC
Sbjct: 816 PPGRAGPRC 824
Score = 32.7 bits (73), Expect = 2.1
Identities = 17/52 (32%), Positives = 24/52 (46%), Gaps = 10/52 (19%)
Query: 1064 FRC---DGYKGYDLVYSPQSGFTCVSPCSRGYCDHGGQCQHLPSGPRCSCVS 1112
+RC DGY G + + + C+ C +GG C +PSG C C S
Sbjct: 331 YRCTCPDGYSGRNCEKAEHA-------CTSNPCANGGSCHEVPSGFECHCPS 375
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 45.8 bits (107), Expect = 2e-04
Identities = 40/144 (27%), Positives = 52/144 (36%), Gaps = 38/144 (26%)
Query: 824 CKCDGGTFGRYC-EGSEDACEEPCFPSVHCV--------------PGKGCEACPPNLTGD 868
C CD G G YC E +D +PC C+ G+ C+ P + D
Sbjct: 622 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 681
Query: 869 GRH----CAALGSSFLC-------------QNQSCPVNYCYNQGHCYISQTLGCQPMCTC 911
H C L + F C + C C N G CY S G C C
Sbjct: 682 PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDS---GDTFRCAC 738
Query: 912 PPAFTDSRCFLAGNNF---SPTVN 932
PP + S C +A N+ +P VN
Sbjct: 739 PPGWKGSTCAVAKNSSCLPNPCVN 762
Score = 42.7 bits (99), Expect = 0.002
Identities = 37/129 (28%), Positives = 48/129 (37%), Gaps = 15/129 (11%)
Query: 799 HCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKGC 858
+C + C T N+ + C C G GR CE +E AC S C G C
Sbjct: 310 YCGSHHPCTNGGTCI--NAEPDQYRCTCPDGYSGRNCEKAEHAC-----TSNPCANGGSC 362
Query: 859 EACPPNLTGDGRHCAALGSSFLC--QNQSCPVNYCYNQGHCYISQTLGCQPMCTCPPAFT 916
P +G HC + S C C N C G C + Q G + C CP +
Sbjct: 363 HEVP---SGFECHCPSGWSGPTCALDIDECASNPCAAGGTC-VDQVDGFE--CICPEQWV 416
Query: 917 DSRCFLAGN 925
+ C L N
Sbjct: 417 GATCQLDAN 425
Score = 39.3 bits (90), Expect = 0.022
Identities = 36/130 (27%), Positives = 45/130 (34%), Gaps = 36/130 (27%)
Query: 824 CKCDGGTFGRYCEGSEDACEE-------PCFPS-----VHCVPG-KGC-------EACPP 863
C CD G G+ C E C+ C+ S C PG KG +C P
Sbjct: 698 CACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLP 757
Query: 864 NLTGDGRHCAALGSSFLC------QNQSCPVNY-------CYNQGHCYISQTLGCQPMCT 910
N +G C G+SF C + ++C N CYN G C C
Sbjct: 758 NPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF---RCE 814
Query: 911 CPPAFTDSRC 920
C P F C
Sbjct: 815 CAPGFAGPDC 824
Score = 38.1 bits (87), Expect = 0.050
Identities = 37/128 (28%), Positives = 44/128 (34%), Gaps = 19/128 (14%)
Query: 798 CHCNAES---QCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEEPCFPSVHCVP 854
CH N QC + T + + + C C G GR+CE D C S C
Sbjct: 458 CHINVNDCRGQCQHGGTCKDLVNGYQ---CVCPRGFGGRHCELERDEC-----ASSPCHS 509
Query: 855 GKGCEACPPNLTGDGRHCAALGSSFLCQ--NQSCPVNYCYNQGHCYISQTLGCQPMCTCP 912
G CE G HC S LC+ C + C N CY L C CP
Sbjct: 510 GGLCEDL---ADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCY---NLEGDYYCACP 563
Query: 913 PAFTDSRC 920
F C
Sbjct: 564 DDFGGKNC 571
Score = 35.8 bits (81), Expect = 0.25
Identities = 27/101 (26%), Positives = 36/101 (35%), Gaps = 22/101 (21%)
Query: 824 CKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKGCEACPPNLTGDGRHCAALGSSFLCQN 883
C+C G GR+C + C P CV G E N C LC
Sbjct: 262 CRCSYGWQGRFC--------DECVPYPGCVHGSCVEPWQCN-------CETNWGGLLCDK 306
Query: 884 QSCPVNYCYNQGHCYISQT-LGCQP---MCTCPPAFTDSRC 920
+NYC + C T + +P CTCP ++ C
Sbjct: 307 D---LNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNC 344
Score = 35.4 bits (80), Expect = 0.32
Identities = 24/76 (31%), Positives = 32/76 (42%), Gaps = 15/76 (19%)
Query: 1052 VTALNVSTLKAYFRCDGYKGYDLVYSPQSGFTC---VSPCSRGYCDHGGQCQHLPSGPRC 1108
+ A + L + CD G+ G C V+ C RG C HGG C+ L +G +C
Sbjct: 433 LNAFSCKNLIGGYYCDCIPGW-------KGINCHINVNDC-RGQCQHGGTCKDLVNGYQC 484
Query: 1109 SCVSFSIYTAWGEHCE 1124
C G HCE
Sbjct: 485 VCPR----GFGGRHCE 496
Score = 33.9 bits (76), Expect = 0.94
Identities = 36/129 (27%), Positives = 45/129 (34%), Gaps = 19/129 (14%)
Query: 798 CHCNAESQCLYNQTSRVGN--SSLEVAGCKCDGGTFGRYCEGSEDACEE-PCFPSVHCVP 854
C S CL N G S C C G GR C + + C PC+ CV
Sbjct: 747 CAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVD 806
Query: 855 GKG---CEACPPNLTGDGRHCAALGSSFLCQNQSCPVNYCYNQGHCYISQTLGCQPMCTC 911
G CE C P G + + QS P Y G + + G + C+C
Sbjct: 807 GVNWFRCE-CAPGFAGPDCRIN------IDECQSSPCAY----GATCVDEINGYR--CSC 853
Query: 912 PPAFTDSRC 920
PP RC
Sbjct: 854 PPGRAGPRC 862
Score = 32.7 bits (73), Expect = 2.1
Identities = 17/52 (32%), Positives = 24/52 (46%), Gaps = 10/52 (19%)
Query: 1064 FRC---DGYKGYDLVYSPQSGFTCVSPCSRGYCDHGGQCQHLPSGPRCSCVS 1112
+RC DGY G + + + C+ C +GG C +PSG C C S
Sbjct: 331 YRCTCPDGYSGRNCEKAEHA-------CTSNPCANGGSCHEVPSGFECHCPS 375
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 45.8 bits (107), Expect = 2e-04
Identities = 55/199 (27%), Positives = 85/199 (42%), Gaps = 31/199 (15%)
Query: 443 PQPA--WMFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNSSFLLQGRTAQTGSAQATNFI 500
P+PA FGDPH T DG F G ++L A+D +S T + + +
Sbjct: 1145 PRPASCMAFGDPHYRTFDGRLLHFQGSCSYVL--AKDCHSGDF---SVHVTNDDRGRSGV 1199
Query: 501 AFAAQYRSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRN 560
A+ + + LG + V+ L + V +D V E E T +L ++
Sbjct: 1200 AWTQEV-AVLLGDMAVRLLQDG----AVTVDGHPVALPFLQEPLLYVELRGHTVILHAQP 1254
Query: 561 GSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTI 620
G +V +DG + V V S+P YQ RT GL G +N +DD + P G +
Sbjct: 1255 GLQVL--WDGQSQVEV-----------SVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLL 1301
Query: 621 PPGSPEEMLFHFGMTWQIN 639
P + FG +WQ++
Sbjct: 1302 PSEAA------FGNSWQVS 1314
Score = 35.8 bits (81), Expect = 0.25
Identities = 31/98 (31%), Positives = 35/98 (35%), Gaps = 18/98 (18%)
Query: 824 CKCDGG--TFGRY-CEGSEDACEEPCFPSVHCVPG-KGC----------EACPPNLTGDG 869
C C GG T GR CE C P PS HC P +GC E P L
Sbjct: 742 CTCLGGFVTCGRRPCE--PPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTC 799
Query: 870 RHCAALGSSFLCQNQSCPVNYC--YNQGHCYISQTLGC 905
C S CQ + CP C + G C+ C
Sbjct: 800 SLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSC 837
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 45.4 bits (106), Expect = 3e-04
Identities = 50/178 (28%), Positives = 70/178 (39%), Gaps = 19/178 (10%)
Query: 448 MFGDPHITTLDGVSYTFNGLGDFLL---VGAQDGNSSFLLQGR--TAQTGSAQATNFIAF 502
M+G H +T DG SYTF G ++L + A+ GN S L TA +A A
Sbjct: 5412 MWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAARCPR 5471
Query: 503 AAQYRSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRNGS 562
A S+ V ++ + +L D V+ F+ GVL+S G+
Sbjct: 5472 ALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVS-----------SGFSKNGVLVSVLGT 5520
Query: 563 EVSASFDGWATVSVIALSNILHASASLPPE-YQNRTEGLLGVWNNNPEDDFRMPNGST 619
VSV + A LP + N TEG G NN DD +G+T
Sbjct: 5521 TTMRVDIPALGVSVTFNGQVF--QARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTT 5576
>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding
protein [Homo sapiens]
Length = 1472
Score = 45.4 bits (106), Expect = 3e-04
Identities = 50/198 (25%), Positives = 74/198 (37%), Gaps = 38/198 (19%)
Query: 450 GDPHITTLDGVSYTFNGLGDFLLV---GAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQY 506
GDPH TT DG Y G + +V D +F ++ + GS
Sbjct: 537 GDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSR------------ 584
Query: 507 RSSSLGPVTVQWLLEPHDAIR-----VLLDNQTVTFQPDHEDGGGQETFNATGVLLSRNG 561
R S +G VTV+ R VL+DNQ +G V S
Sbjct: 585 RVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG-------RLRVYQSGPR 637
Query: 562 SEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIP 621
+ V F V+ + SLP +Q++ GL G +N +P DDF P+G+ P
Sbjct: 638 AVVELVFG-----LVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAP 692
Query: 622 PGSPEEMLFHFGMTWQIN 639
F +W+++
Sbjct: 693 DA------VEFASSWKLD 704
Score = 42.0 bits (97), Expect = 0.003
Identities = 45/188 (23%), Positives = 76/188 (40%), Gaps = 22/188 (11%)
Query: 450 GDPHITTLDGVSYTFNGLGDFLLVGAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQYRSS 509
GDPH + DG + F G +LLVG+ G ++ L R + + +++ R
Sbjct: 929 GDPHYVSFDGRRFDFMGTCTYLLVGS-CGQNAALPAFRVLVENEHRGSQTVSYTRAVRVE 987
Query: 510 SLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRNGSEVSASFD 569
+ G V+ + +VL+D+ + + P G + F + R ++ ++D
Sbjct: 988 ARG---VKVAVRREYPGQVLVDD-VLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYD 1043
Query: 570 GWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIPPGSPEEML 629
A V +A +P Y GL G +N +P DD + G G L
Sbjct: 1044 WNARV-----------TAKVPSSYAEALCGLCGNFNGDPADDLALRGG-----GQAANAL 1087
Query: 630 FHFGMTWQ 637
FG +WQ
Sbjct: 1088 -AFGNSWQ 1094
>gi|62988324 tenascin N [Homo sapiens]
Length = 1299
Score = 45.1 bits (105), Expect = 4e-04
Identities = 41/144 (28%), Positives = 49/144 (34%), Gaps = 33/144 (22%)
Query: 800 CNAESQC-----LYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEEPCFPSVHCVP 854
C+A+ C L S G SLE C C+ G G CE AC C CV
Sbjct: 126 CSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACE--RLACPGACSGHGRCVD 183
Query: 855 GK------------GCEACPPNLTGDGR------HCAALGSSFLCQNQSCPVNYCYNQGH 896
G+ G ACP N +G G C S C + CP + C G
Sbjct: 184 GRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGD-CSGHGF 242
Query: 897 CYISQTLGCQPMCTCPPAFTDSRC 920
C + C C FT C
Sbjct: 243 CDTGE-------CYCEEGFTGLDC 259
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 44.7 bits (104), Expect = 5e-04
Identities = 54/206 (26%), Positives = 82/206 (39%), Gaps = 29/206 (14%)
Query: 437 CATYRPPQPAWMFGDPHITTLDGVSYTFNGLGDFLLV-GAQDGNSSFLLQG-RTAQTGSA 494
C+ P + G H + D +TF+G+ +LL QD + S +++ + A A
Sbjct: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDA 438
Query: 495 QATNFIAFAAQYRSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATG 554
T + +SL + H A V +D Q V D Q T A+
Sbjct: 439 VCTRSVTVRLPGLHNSLVKLK-------HGA-GVAMDGQDVQLPLLKGDLRIQHTVTAS- 489
Query: 555 VLLSRNGSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRM 614
V LS G ++ +DG + V L P Y +T GL G +N N DDF
Sbjct: 490 VRLSY-GEDLQMDWDGRGRLLV-----------KLSPVYAGKTCGLCGNYNGNQGDDFLT 537
Query: 615 PNGSTIPPGSPEEMLFHFGMTWQING 640
P+G E + FG W+++G
Sbjct: 538 PSGLA------EPRVEDFGNAWKLHG 557
>gi|239757284 PREDICTED: similar to Fc fragment of IgG binding
protein [Homo sapiens]
Length = 593
Score = 44.7 bits (104), Expect = 5e-04
Identities = 49/196 (25%), Positives = 78/196 (39%), Gaps = 23/196 (11%)
Query: 447 WMFGDPHITTLDGVSYTFNGLGDFLLVGAQDGNSSFLLQGRTAQTGSAQATNFIAFAAQY 506
W++GDPH + DG + F G +++L A G QG T T + + N A Y
Sbjct: 373 WLWGDPHYHSFDGRKFDFQGTCNYVL--ATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSY 430
Query: 507 -RSSSLGPVTVQWLLEPHDAIRVLLDNQTVTFQPDHEDGGGQETFNATGVLLSRN-GSEV 564
R ++ + + + +V ++ DG T A+ LL + G +V
Sbjct: 431 VRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQV 490
Query: 565 SASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNGSTIPPGS 624
S ++ W +LP Y GL G + NP +D PNG T+ P
Sbjct: 491 SYDWN-W------------RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG-TLAPSI 536
Query: 625 PEEMLFHFGMTWQING 640
P +G +W+ G
Sbjct: 537 P-----IWGGSWRAPG 547
Score = 40.4 bits (93), Expect = 0.010
Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 9/80 (11%)
Query: 558 SRNGSEVSASFDGWATVSVIALSNILHASASLPPEYQNRTEGLLGVWNNNPEDDFRMPNG 617
S++GS+V D V A + + ++P Y + GL G +N +P+DDF+ PNG
Sbjct: 15 SQHGSDVVIETDFGLRV---AYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNG 71
Query: 618 STIPPGSPEEMLFHFGMTWQ 637
S G+ E FG +W+
Sbjct: 72 S--QAGNANE----FGNSWE 85
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,913,748
Number of Sequences: 37866
Number of extensions: 2699742
Number of successful extensions: 8092
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 189
Number of HSP's that attempted gapping in prelim test: 6453
Number of HSP's gapped (non-prelim): 1707
length of query: 1176
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1063
effective length of database: 13,968,660
effective search space: 14848685580
effective search space used: 14848685580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.