Guide to the Human Genome
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Search of human proteins with 169205942

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]
         (564 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]          1159   0.0  
gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]          1159   0.0  
gi|169206171 PREDICTED: hypothetical protein [Homo sapiens]           715   0.0  
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    65   2e-10
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      63   8e-10
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       58   2e-08
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        58   3e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni...    57   3e-08
gi|182507165 thymus expressed gene 3-like [Homo sapiens]               57   4e-08
gi|239752764 PREDICTED: hypothetical protein [Homo sapiens]            56   8e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    56   1e-07
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      55   1e-07
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    55   2e-07
gi|153792074 proline rich 12 [Homo sapiens]                            54   3e-07
gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]            54   4e-07
gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]            54   4e-07
gi|57864582 hornerin [Homo sapiens]                                    53   6e-07
gi|239750121 PREDICTED: hypothetical protein XP_002347280 [Homo ...    53   6e-07
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             53   6e-07
gi|113430175 PREDICTED: hypothetical protein [Homo sapiens]            53   8e-07
gi|239745974 PREDICTED: hypothetical protein XP_002343630 [Homo ...    52   1e-06
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          51   2e-06
gi|122692281 hypothetical protein LOC645369 [Homo sapiens]             51   2e-06
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     51   3e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    50   4e-06
gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]            50   5e-06
gi|239749538 PREDICTED: hypothetical protein XP_002347080 [Homo ...    50   5e-06
gi|239743688 PREDICTED: hypothetical protein XP_002342946 [Homo ...    50   5e-06
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    50   7e-06
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    50   7e-06

>gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 564

 Score = 1159 bits (2998), Expect = 0.0
 Identities = 564/564 (100%), Positives = 564/564 (100%)

Query: 1   MEGKEKSFHHRGGTATVNVLPSLGEKALTALSHQNPEFPQIARNDCWDRVPRGSVTDSNH 60
           MEGKEKSFHHRGGTATVNVLPSLGEKALTALSHQNPEFPQIARNDCWDRVPRGSVTDSNH
Sbjct: 1   MEGKEKSFHHRGGTATVNVLPSLGEKALTALSHQNPEFPQIARNDCWDRVPRGSVTDSNH 60

Query: 61  TPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDC 120
           TPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDC
Sbjct: 61  TPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDC 120

Query: 121 AGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARR 180
           AGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARR
Sbjct: 121 AGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARR 180

Query: 181 KTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRAC 240
           KTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRAC
Sbjct: 181 KTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRAC 240

Query: 241 PGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAA 300
           PGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAA
Sbjct: 241 PGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAA 300

Query: 301 RASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPA 360
           RASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPA
Sbjct: 301 RASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPA 360

Query: 361 QGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGR 420
           QGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGR
Sbjct: 361 QGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGR 420

Query: 421 GSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGA 480
           GSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGA
Sbjct: 421 GSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGA 480

Query: 481 GRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRGAGVPWR 540
           GRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRGAGVPWR
Sbjct: 481 GRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRGAGVPWR 540

Query: 541 TQTLSLLRRCSGALRELESPFPDS 564
           TQTLSLLRRCSGALRELESPFPDS
Sbjct: 541 TQTLSLLRRCSGALRELESPFPDS 564


>gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 564

 Score = 1159 bits (2998), Expect = 0.0
 Identities = 564/564 (100%), Positives = 564/564 (100%)

Query: 1   MEGKEKSFHHRGGTATVNVLPSLGEKALTALSHQNPEFPQIARNDCWDRVPRGSVTDSNH 60
           MEGKEKSFHHRGGTATVNVLPSLGEKALTALSHQNPEFPQIARNDCWDRVPRGSVTDSNH
Sbjct: 1   MEGKEKSFHHRGGTATVNVLPSLGEKALTALSHQNPEFPQIARNDCWDRVPRGSVTDSNH 60

Query: 61  TPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDC 120
           TPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDC
Sbjct: 61  TPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDC 120

Query: 121 AGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARR 180
           AGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARR
Sbjct: 121 AGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARR 180

Query: 181 KTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRAC 240
           KTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRAC
Sbjct: 181 KTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRAC 240

Query: 241 PGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAA 300
           PGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAA
Sbjct: 241 PGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAA 300

Query: 301 RASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPA 360
           RASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPA
Sbjct: 301 RASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPA 360

Query: 361 QGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGR 420
           QGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGR
Sbjct: 361 QGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGR 420

Query: 421 GSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGA 480
           GSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGA
Sbjct: 421 GSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGA 480

Query: 481 GRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRGAGVPWR 540
           GRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRGAGVPWR
Sbjct: 481 GRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRGAGVPWR 540

Query: 541 TQTLSLLRRCSGALRELESPFPDS 564
           TQTLSLLRRCSGALRELESPFPDS
Sbjct: 541 TQTLSLLRRCSGALRELESPFPDS 564


>gi|169206171 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 466

 Score =  715 bits (1846), Expect = 0.0
 Identities = 397/567 (70%), Positives = 408/567 (71%), Gaps = 104/567 (18%)

Query: 1   MEGKEKSFHHRGGTATVNVLPSLGEKALTALSHQNPEFPQIARNDCWDRVPRGSVTDSNH 60
           MEGKEKSFHHRGGTATVNVLPSLGEKALTALSHQNPEFPQIARNDCWDRVPRGSVTDSNH
Sbjct: 1   MEGKEKSFHHRGGTATVNVLPSLGEKALTALSHQNPEFPQIARNDCWDRVPRGSVTDSNH 60

Query: 61  TPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDC 120
           TPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDC
Sbjct: 61  TPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDC 120

Query: 121 AGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARR 180
           AGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGR SHSGPRAGTPGGGRSSRAGARR
Sbjct: 121 AGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRASHSGPRAGTPGGGRSSRAGARR 180

Query: 181 KTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRAC 240
           KTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRAC
Sbjct: 181 KTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRAC 240

Query: 241 PGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGR--PTGERSSREPLLDPSK 298
           PGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHST G R  PT  R+       P K
Sbjct: 241 PGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHST-GARTLPTPSRAR------PGK 293

Query: 299 AARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALE 358
            A   + P AR+             R GGG    T L G               SGR   
Sbjct: 294 PAPRGSAPPARL-------------RGGGGGSGLTQLVG---------------SGR--- 322

Query: 359 PAQGSELWARAERHGGSSGARTLPTPSRA-RPGKPAPRGSAPPARLRGGGGGSGLTQLVG 417
                          GS    ++ T + A R G  APR   P   LR             
Sbjct: 323 ---------------GSGVTHSVGTHALATRRGSRAPR---PVGVLR------------- 351

Query: 418 SGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPR 477
                GV H     + A +   R+P        V  F P       S P++P        
Sbjct: 352 -----GVPHFRPLSSPAPQSPPRSP-------SVRAFGPRLGAGRLSCPQAP-------- 391

Query: 478 LGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRGAGV 537
                       RAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRGAGV
Sbjct: 392 ------------RAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRGAGV 439

Query: 538 PWRTQTLSLLRRCSGALRELESPFPDS 564
           PWRTQTLSLLRRCSGALRELESPFPDS
Sbjct: 440 PWRTQTLSLLRRCSGALRELESPFPDS 466


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 105/431 (24%), Positives = 153/431 (35%), Gaps = 73/431 (16%)

Query: 109 RSRRAAGPGLDCAGSAPAPSGAQSCGGPAPASALR----------RPLTQWDASGGGGRG 158
           R+  A  PGL      P P G+     P   +ALR          +PL +     GG   
Sbjct: 15  RTPAARAPGL----LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70

Query: 159 SHSGPRAG------TPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSW------ 206
             S PRAG       P  GR  RA   + T         R   + R   LG         
Sbjct: 71  PESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 130

Query: 207 ----GGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGH 262
                G  T  P R+       +AGAR    G      PG+  P  +  +   GT     
Sbjct: 131 ETVARGKATEAPKRSAL-----SAGARRDTSG----PTPGTPSPAMARRSRAAGTEV--- 178

Query: 263 GGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQ 322
            G+ R   SA     T G R +   +S     +PS AAR        +   +  SL+++ 
Sbjct: 179 -GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 237

Query: 323 WRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLP 382
             L    R     +G  R     ++ + P+  +AL P Q +     A    G   +  L 
Sbjct: 238 TPLSSPARSGPSARGTPRAPAHPSQPK-PKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 296

Query: 383 TPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAP 442
           TPS + P  P    SAPP+            Q + S   +  + +  +    T + + + 
Sbjct: 297 TPSPSAPPSP----SAPPS-----------LQTLPSPPATPPSQATTSLGSPTLQATHSF 341

Query: 443 RPVGVLRGVPHFRPLSSPAPQSPP-------RSPSVRAFGPRLGAGRLSCPQAPRAAALP 495
            P       P   PL++P PQ+PP       ++P      P L       PQAP A A+ 
Sbjct: 342 LP------SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 395

Query: 496 GI-AVLAPSPA 505
            + A  +P P+
Sbjct: 396 LLQAPFSPPPS 406



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 109/468 (23%), Positives = 155/468 (33%), Gaps = 100/468 (21%)

Query: 48  DRVPRGSVTDSNHTPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWG 107
           + V RG  T++          P R + S   RR           P+  RR+  A T +  
Sbjct: 131 ETVARGKATEA----------PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 180

Query: 108 RRSRRAAGPGLDCAGSAPAPSGA--QSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRA 165
            R   +A P     G   + S A   S   P+PA A RRP      S GGG         
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA-ARRRP------SAGGGLQR------ 227

Query: 166 GTPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGA 225
                  +SR+ +   TPLS      R G S R           GTP  P         A
Sbjct: 228 ------PASRSLSSSATPLS---SPARSGPSAR-----------GTPRAP---------A 258

Query: 226 AGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTG 285
             ++ + +G +    P  T PP    A  +G  +            +PS+  +    P+ 
Sbjct: 259 HPSQPKPKGLQALRPPQVT-PPRKDAAPALGPLSSSPLAT-----PSPSAPPSPSAPPSL 312

Query: 286 ERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLST 345
           +     P   PS+A  +   PT +  H+  PS   +       +  P          L+ 
Sbjct: 313 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA---------LAL 363

Query: 346 AEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRG 405
              + P S  A  P   S L   + +   +     L  P    P  P     +PPA    
Sbjct: 364 PPLQAPPSPPASPPL--SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS--- 418

Query: 406 GGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSP 465
                           S    S    +LA       P P       P   P ++P PQ+P
Sbjct: 419 -----------PPVSPSATPPSQAPPSLAAPPLQVPPSP----PASPPMSPSATPPPQAP 463

Query: 466 P--RSPSVRAFGPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQ 511
           P   +P ++   P         PQAP A A P +  L PSP   + GQ
Sbjct: 464 PPLAAPPLQLAKPP--------PQAPPALATPPLQAL-PSPPASFPGQ 502



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 116/504 (23%), Positives = 150/504 (29%), Gaps = 44/504 (8%)

Query: 63  AGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCAG 122
           AG + G  RP+ S   R P +    +VS  S    T  +  A    R R +AG GL    
Sbjct: 174 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA----RRRPSAGGGLQRPA 229

Query: 123 SAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARRKT 182
           S    S A     PA +    R   +  A     +    G +A  P      R  A    
Sbjct: 230 SRSLSSSATPLSSPARSGPSARGTPR--APAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 287

Query: 183 -PLSLCPLKLRKGSSRRCQGLGSSWGGSGTPP--PPRALWNRHGGAAGARAQVRGSEKRA 239
            PLS  PL     S+        S     +PP  PP       G                
Sbjct: 288 GPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 347

Query: 240 CPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDP--- 296
            P +T PP +  A  +               S  ++ S            + P   P   
Sbjct: 348 SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 407

Query: 297 ------SKAARASALPTARVAHASPPSLAAAQWRLGGGK-RKPTVLKGAVRTDLSTAEEE 349
                 S  A     P+A     +PPSLAA   ++       P +   A     +     
Sbjct: 408 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 467

Query: 350 DPRSGRALEPAQGSELWARAERHGGSSGARTLP-----TPSRARPGKP--APRGSAPPAR 402
            P    A  P Q     A        S   + P     +PS + P  P   P   APP  
Sbjct: 468 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 527

Query: 403 LRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAP 462
                  + L Q+  S   S          L   R    P P   + G      L+   P
Sbjct: 528 ------AAPLLQVPPSPPASPT--------LQAPRRPPTPGPDTSVSGPRLTLALAPGPP 573

Query: 463 QSPPRSPSVRAFGPRL---GAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGG 519
             P RSPS    GP L    +   S P+  R          A SP  D     C      
Sbjct: 574 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 633

Query: 520 SQPFAGRRAERGKRGAGVPWRTQT 543
             P A   A RG  GA +PW   T
Sbjct: 634 RGP-APPLAFRGAPGAPLPWPPAT 656



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 66/262 (25%), Positives = 80/262 (30%), Gaps = 46/262 (17%)

Query: 111 RRAAGPGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGG 170
           RR   PG D + S P  + A + G P P S  R P +      G     HS     TP  
Sbjct: 548 RRPPTPGPDTSVSGPRLTLALAPGPPPPPS--RSPSS---TLSGPDLAGHSSSATSTPEE 602

Query: 171 GRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARA 230
            R   +G                             GG+   PPP A       AA +R 
Sbjct: 603 LRGYDSGPE---------------------------GGAAASPPPDAELAACHPAAWSRG 635

Query: 231 QVRGSEKRACPGSTLP------PSSVLAGCVGTRARGHGGVQRQ--RFSAPSSHSTSGGR 282
                  R  PG+ LP      P S    C      G               S  TSGG+
Sbjct: 636 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGK 695

Query: 283 PT----GERSSREPLLDPSKAARASALPTARVAHASPPS--LAAAQWRLGGGKRKPTVLK 336
                    SSR P           AL  + V H    +  LAAA+   GG    P   +
Sbjct: 696 AAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAE 755

Query: 337 GAVRTDLSTAEEEDPRSGRALE 358
           G   T  + A   D   GR  E
Sbjct: 756 GGGVTGGARAALSDAELGRWAE 777



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 29/95 (30%), Positives = 37/95 (38%), Gaps = 10/95 (10%)

Query: 436 RRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAGRLSCPQAPRAAALP 495
           + G+ A  P     G+   RP  SP P  P    ++R  G     GR   P A RA  + 
Sbjct: 9   KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK--PLAERAGGIG 66

Query: 496 GIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAER 530
           G  +  P  A   G  R       S+P A  R ER
Sbjct: 67  GATI--PESAPRAGPTRT------SRPPASGRGER 93


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 133/512 (25%), Positives = 165/512 (32%), Gaps = 92/512 (17%)

Query: 62  PAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCA 121
           P GL   P  P        P + GE   SGP   R                A  PG    
Sbjct: 186 PRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGK--NGDDGEAGKPGRPGE 243

Query: 122 GSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRA--GTPG-GGRSSRAGA 178
              P P GA+   G A    ++         G  G    +GP+   G+PG  G   + G 
Sbjct: 244 RGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGP 303

Query: 179 RRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKR 238
           R                     GL    G  G P P  A  N   GA GA          
Sbjct: 304 R---------------------GLPGERGRPGAPGPAGARGN--DGATGAAGP------- 333

Query: 239 ACPGSTLPPSSV-LAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPS 297
             PG T P       G VG  A+G  G Q  R S           P G   +  P  +P 
Sbjct: 334 --PGPTGPAGPPGFPGAVG--AKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPG 389

Query: 298 KAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRAL 357
               A   P A+ A+ +P    A  +    G R P+  +G             P+     
Sbjct: 390 ----ADGQPGAKGANGAPGIAGAPGF---PGARGPSGPQG-------PGGPPGPKGNSGE 435

Query: 358 EPAQGSELWARAERHGGSSGARTLPTPS-----RARPGKPAPRGSAPPARLRGGGGGSGL 412
             A GS+    A+   G  G +  P P+     R   G+P P G   P   RGG G  G 
Sbjct: 436 PGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGF 495

Query: 413 TQLVGSGRGSGVTHSVGTHALATRRGS--RAPRPVGVLRGVPHFRPLS----SPAPQ--- 463
               G     G     G+   A  +GS   A RP     G+P  + L+    SP P    
Sbjct: 496 PGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEA--GLPGAKGLTGSPGSPGPDGKT 553

Query: 464 ------------SPPRSPSVRAFGPRLGAGRLSCPQAPRAAALPGIA----VLAPSPAHD 507
                        PP  P     G R  AG +  P    AA  PG A    V  P  A  
Sbjct: 554 GPPGPAGQDGRPGPPGPP-----GARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVG 608

Query: 508 WGGQRCEGCGGGSQPFAGRRAERGKRG-AGVP 538
             G+  E    G    AG   ERG++G AG P
Sbjct: 609 PAGKDGEAGAQGPPGPAGPAGERGEQGPAGSP 640



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 113/456 (24%), Positives = 147/456 (32%), Gaps = 72/456 (15%)

Query: 51   PRGSVTDSNHTPAGLDCGPTRPSGSLTTR-RPRDAGEAAVSGPSRQRRTSRARTALWGRR 109
            P G+  D   +      GPT   G+   R  P   G A  +GP        A+       
Sbjct: 774  PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAG 833

Query: 110  SRRAAGPGLDCAGS----------APAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGS 159
            ++  AGP      +          AP   GA+   GP  A+            G  GR  
Sbjct: 834  AKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGF---------PGAAGRVG 884

Query: 160  HSGP--RAGTPG----GGRSSRAGARRKTPLSLCPLKL------RKGSSRRCQGLGSSWG 207
              GP   AG PG     G+    G R +T  +  P ++           +   G     G
Sbjct: 885  PPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAG 944

Query: 208  GSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPG----STLPPSSVLAGCVGTRARGHG 263
              GTP P      R  G  G   Q RG  +R  PG    S  P     +G  G R    G
Sbjct: 945  APGTPGPQGIAGQR--GVVGLPGQ-RG--ERGFPGLPGPSGEPGKQGPSGASGERG-PPG 998

Query: 264  GVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQW 323
             +     + P   S   G P  E S   P  D S  A+     T        P    A  
Sbjct: 999  PMGPPGLAGPPGESGREGAPGAEGS---PGRDGSPGAKGDRGETGPAGPPGAPGAPGAPG 1055

Query: 324  RLG-------GGKRKPTVLKGAVRT--DLSTAEEEDPRSGRALEPAQGSELWARAERHGG 374
             +G        G+  P    G V        A  + PR  +     QG       + H G
Sbjct: 1056 PVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDR---GIKGHRG 1112

Query: 375  SSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALA 434
             SG +  P P    PG+  P G++ PA  RG  G +G     G    +G+   +G     
Sbjct: 1113 FSGLQGPPGPP-GSPGEQGPSGASGPAGPRGPPGSAGAP---GKDGLNGLPGPIGPPGPR 1168

Query: 435  TRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPS 470
             R G     PVG         P   P P  PP  PS
Sbjct: 1169 GRTGDAG--PVG---------PPGPPGPPGPPGPPS 1193



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 123/492 (25%), Positives = 155/492 (31%), Gaps = 69/492 (14%)

Query: 81  PRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCAGSAPAPSGAQSCGGPAPAS 140
           P + G     GP+  R    A  A         AGP        P   GA+   GP    
Sbjct: 307 PGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPP-----GFPGAVGAKGEAGPQGPR 361

Query: 141 ALRRPLTQWDASGGGGRGSHSGPRAGTPGG-GRSSRAGARRKTPLSLCPLKLRKGSSRRC 199
               P       G  G    +GP AG PG  G+    GA     ++  P           
Sbjct: 362 GSEGPQGVRGEPGPPGPAGAAGP-AGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGP 420

Query: 200 QGLGSSWGGSGTPPPPRALWNRHGGAAGARAQ-----VRGSE-------KRACPGSTLPP 247
           QG G   G  G    P A  ++  G  GA+ +     V+G         KR   G   P 
Sbjct: 421 QGPGGPPGPKGNSGEPGAPGSK--GDTGAKGEPGPVGVQGPPGPAGEEGKRGARGE--PG 476

Query: 248 SSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGR-PTGERSSREPLL---DPSKAARA- 302
            + L G  G R    GG   + F  P +   +G + P GER S  P      P +A R  
Sbjct: 477 PTGLPGPPGER----GGPGSRGF--PGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPG 530

Query: 303 -SALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQ 361
            + LP A+    SP S          GK  P    G    D        P   R      
Sbjct: 531 EAGLPGAKGLTGSPGSPGP------DGKTGPP---GPAGQD-GRPGPPGPPGARGQAGVM 580

Query: 362 GSELWARAERHGGSSGARTLPTPSRA-----------RPGKPAPRGSAPPARLRGGGGGS 410
           G      A    G +G R +P P  A             G P P G A     +G  G  
Sbjct: 581 GFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSP 640

Query: 411 GLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPS 470
           G   L G     G     G   +    G+  P      RG P  R +  P   + PR  +
Sbjct: 641 GFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGAN 700

Query: 471 VRAFGPRLGAGRLSCPQAPRAAALPGI--------AVLAPSPAHDWGGQRCEGCGGGSQP 522
             A G     G    P AP +   PG+        A   P P  D G    +G  G    
Sbjct: 701 -GAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGS--- 756

Query: 523 FAGRRAERGKRG 534
             G+   RG  G
Sbjct: 757 -PGKDGVRGLTG 767



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 109/453 (24%), Positives = 141/453 (31%), Gaps = 95/453 (20%)

Query: 68   GPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGP----------G 117
            GP  P+G+     P D GE+  SGP+     + AR A   R      GP          G
Sbjct: 770  GPPGPAGA-----PGDKGESGPSGPAGP---TGARGAPGDRGEPGPPGPAGFAGPPGADG 821

Query: 118  LDCAGSAPAPSGAQSCGGP---APASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSS 174
               A   P  +GA+   GP   A  +    P+    A G  G    +GP   T   G + 
Sbjct: 822  QPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAG 881

Query: 175  RAG-----ARRKTPLSLCPLKLRKGSSRRCQ-GLGSSWGGSGTPPPPRALWNRHGGAAGA 228
            R G          P    P     G   R + G     G  G P PP        G AG 
Sbjct: 882  RVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPP--------GPAGE 933

Query: 229  RAQVRGSEKRACPGSTLPPSSV----LAGCVGTRA-RGHGGVQRQRFSAPSSHSTSGGRP 283
            +           PG+  P        + G  G R  RG  G+       P     SG   
Sbjct: 934  KGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPS-GEPGKQGPSGA-- 990

Query: 284  TGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDL 343
            +GER    P+                     PP LA      G         +GA   + 
Sbjct: 991  SGERGPPGPM--------------------GPPGLAGPPGESGR--------EGAPGAEG 1022

Query: 344  STAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARL 403
            S   +  P               A+ +R  G +G    P    A PG P P G A  +  
Sbjct: 1023 SPGRDGSPG--------------AKGDR--GETGPAGPPGAPGA-PGAPGPVGPAGKSGD 1065

Query: 404  RGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQ 463
            RG  G +G    VG     G     G        G +  R +   RG    +      P 
Sbjct: 1066 RGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQ-----GPP 1120

Query: 464  SPPRSPSVRAFGPRLGAGRLSCPQAPRAAALPG 496
             PP SP  +  GP   +G       P +A  PG
Sbjct: 1121 GPPGSPGEQ--GPSGASGPAGPRGPPGSAGAPG 1151



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 108/422 (25%), Positives = 135/422 (31%), Gaps = 41/422 (9%)

Query: 124  APAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPR--AGTPGGGRSSRAGARRK 181
            AP PSGA+   G      ++ P       G  G   + G +  AG PG   S  A   + 
Sbjct: 669  APGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQG 728

Query: 182  TPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNR-HGGAAGARAQVRGSEKRAC 240
             P             R   GL    G  G   P  A  +    G  G    +        
Sbjct: 729  MP-----------GERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGA 777

Query: 241  PGSTLPPSSVLAGCVG-TRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKA 299
            PG      S  +G  G T ARG  G  R     P     +G  P G         +P  A
Sbjct: 778  PGDK--GESGPSGPAGPTGARGAPG-DRGEPGPPGPAGFAG--PPGADGQPGAKGEPGDA 832

Query: 300  -ARASALPTARVAHASPPSLAAAQWRLGG-GKRKPTVLKGAVRTDLSTAEEEDPR-SGRA 356
             A+  A P      A PP         G  G R      GA     +      P  SG A
Sbjct: 833  GAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNA 892

Query: 357  LEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLV 416
              P         A + GG  G R    P+  RPG+  P G   PA  +G  G  G     
Sbjct: 893  GPPGPPGP----AGKEGGK-GPRGETGPA-GRPGEVGPPGPPGPAGEKGSPGADGPAGAP 946

Query: 417  GSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGP 476
            G+    G+    G   L  +RG R         G+P   P   P  Q P  +   R    
Sbjct: 947  GTPGPQGIAGQRGVVGLPGQRGERG------FPGLP--GPSGEPGKQGPSGASGERGPPG 998

Query: 477  RLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRGAG 536
             +G   L+ P  P  +   G      SP  D G    +G  G + P AG     G  GA 
Sbjct: 999  PMGPPGLAGP--PGESGREGAPGAEGSPGRD-GSPGAKGDRGETGP-AGPPGAPGAPGAP 1054

Query: 537  VP 538
             P
Sbjct: 1055 GP 1056



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 90/336 (26%), Positives = 109/336 (32%), Gaps = 34/336 (10%)

Query: 201 GLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRAR 260
           GL    G  G P PP        G   A     G ++++  G ++P     +G  G    
Sbjct: 139 GLPGPPGPPGPPGPPGL------GGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGP 192

Query: 261 GHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAAR-ASALPTARVAHASPPSLA 319
             G    Q F  P       G  +G    R P   P K      A    R     PP   
Sbjct: 193 P-GAPGPQGFQGPPGEPGEPGA-SGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQ 250

Query: 320 AAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGAR 379
            A+  L G    P +      + L  A+ +   +G   EP    E  A      G  G R
Sbjct: 251 GARG-LPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAP-----GQMGPR 304

Query: 380 TLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGS 439
            LP   R RPG P P G+       G  G  G T   G     G   + G       RGS
Sbjct: 305 GLPG-ERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS 363

Query: 440 RAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAGRLSCPQAPRAAALPGIAV 499
             P+ V   RG         P P  P       A GP    G    P A  A   PGIA 
Sbjct: 364 EGPQGV---RG--------EPGPPGP-----AGAAGPAGNPGADGQPGAKGANGAPGIAG 407

Query: 500 LAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRGA 535
            AP      G    +G GG   P  G   E G  G+
Sbjct: 408 -APGFPGARGPSGPQGPGGPPGP-KGNSGEPGAPGS 441


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 130/507 (25%), Positives = 164/507 (32%), Gaps = 75/507 (14%)

Query: 65  LDCG-PTRPSGS---LTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRR--AAGPGL 118
           LDC  P  P G    + ++ P         G   Q+        + G R R   A  PG 
Sbjct: 80  LDCADPVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGS 139

Query: 119 DCAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGA 178
                   P G     GP           Q  A G  G  SH GP  G      +  AG 
Sbjct: 140 QGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPD-GLSRPFSAQMAGL 198

Query: 179 RRKTPLS----LCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHG----GAAGARA 230
             K+ L     L P  +     R  QGL    GG+G   PP    +       G+ G   
Sbjct: 199 DEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEG 258

Query: 231 QVRGSEKRACPGSTLPPSSV-LAGCVGTRA-------------RGHGGVQ--RQRFSAPS 274
                 +   PG    P  V  AG  G R              RGH G++  +    AP 
Sbjct: 259 PPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPG 318

Query: 275 SHSTSGGRPTGERSSREPLLD---PSKAARAS--ALPTARVAHASP-----------PSL 318
           S   +G  PTG   +  PL     P +  R      P  R AH  P           P  
Sbjct: 319 SKGEAG--PTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGS 376

Query: 319 AAAQWRLG-GGKRKPTVLKGAVRTDLSTAEEEDPR--SGRALEPAQGSELWARAERHGGS 375
           +      G  G+  PT  +G         E   P       L  A G++    A+   GS
Sbjct: 377 SGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGS 436

Query: 376 SGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSG--RGS----GVTHSVG 429
            G    P  S   PG P P+GS  P  +RG  G  G+    G    +G     G+   +G
Sbjct: 437 PGTSG-PPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIG 495

Query: 430 THALATRRGSRA-------PRPVGVL-----RGVPHFRPLSSPAPQSPPRSPSVRAFGPR 477
                 +RG R        P PVG       RG P    L  P      R P V + GP+
Sbjct: 496 PPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGP-VGSSGPK 554

Query: 478 LGAGRLSCPQAPRAAALPGIAVLAPSP 504
              G    P  P    LPG   L  +P
Sbjct: 555 ---GSQGDPGRPGEPGLPGARGLTGNP 578



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 107/438 (24%), Positives = 133/438 (30%), Gaps = 66/438 (15%)

Query: 53   GSVTDSNHTPAGLDCGPTRPSGSLTTR----RPRDAGEAAVSGP-----SRQRRTSRART 103
            GS  ++  T A    GP  P G    +     P   G+A   GP     S          
Sbjct: 834  GSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVP 893

Query: 104  ALWGRRSRRAAGPGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHS-- 161
             L G R  +         GSA         G P PA  L  P  +      G  GSH   
Sbjct: 894  GLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRV 953

Query: 162  ---GPRAGTPGG-GRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRA 217
               GP AG PGG G     G   +      P        R   G+    G  G P  P  
Sbjct: 954  GDRGP-AGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGP 1012

Query: 218  LWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHS 277
                  G  G       +  +  PG   PP S            +G V       P+ + 
Sbjct: 1013 -----AGTPGKVGPTGATGDKGPPGPVGPPGS------------NGPVGEPGPEGPAGND 1055

Query: 278  TSGGRP--TGERSSREPLLDPSKAARASALPTARVAHASPPSLAA---AQWRLGGGKRKP 332
             + GR    GER  R    DP  A     LP ++ A  +P  + A   A  R   G R P
Sbjct: 1056 GTPGRDGAVGERGDRG---DPGPAG----LPGSQGAPGTPGPVGAPGDAGQRGDPGSRGP 1108

Query: 333  TVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKP 392
                G           + PR  +     +G       + H G +G + LP P       P
Sbjct: 1109 IGPPGRAGKR-GLPGPQGPRGDKGDHGDRGDR---GQKGHRGFTGLQGLPGP-------P 1157

Query: 393  APRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPR-PVGVLRGV 451
             P G    A + G  G  G    VG     G    +G       RGS     P G     
Sbjct: 1158 GPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEG----- 1212

Query: 452  PHFRPLSSPAPQSPPRSP 469
                P   P P  PP  P
Sbjct: 1213 ----PPGEPGPPGPPGPP 1226



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 123/503 (24%), Positives = 151/503 (30%), Gaps = 91/503 (18%)

Query: 81  PRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCAGSAPAPSGAQSCGG-PAPA 139
           P   GEA  +GP         R  + G R R   GP       AP   GA    G P P 
Sbjct: 317 PGSKGEAGPTGPMGAMGPLGPR-GMPGERGR--LGPQ-----GAPGQRGAHGMPGKPGPM 368

Query: 140 SALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRC 199
             L  P +       G +G      A  P G +  R       P+               
Sbjct: 369 GPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVG-------------S 415

Query: 200 QGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSV----LAGCV 255
            GL  + G  GTP              GA+           PGS  PP S       G  
Sbjct: 416 PGLPGAIGTDGTP--------------GAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQ 461

Query: 256 GTRAR-GHGGVQRQRFSA-----PSSHSTSGG-RPTGERSSREPLLDPSKAARASALPTA 308
           G R + G  GV   +  A     P  H   G   P GE   R P  DP         P  
Sbjct: 462 GIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVG-----PPG 516

Query: 309 RVAHASPPSLAAAQWRLG-GGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWA 367
            V     P         G  G +     +G V +      + DP  GR  EP        
Sbjct: 517 PVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDP--GRPGEPGLPGARGL 574

Query: 368 RAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSG-------- 419
                      +  P  +    G+P P GS     +RG  G  GL    GS         
Sbjct: 575 TGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIG---IRGQPGSMGLPGPKGSSGDPGKPGE 631

Query: 420 ---------RGS-------GVTHSVGTHALATRRGSRAPRPVGVLRGVP----HFRPLSS 459
                    RG+       G +  VG   LA  RG + P      +G+P           
Sbjct: 632 AGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGK 691

Query: 460 PAPQSPPRSP-SVRAFGPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDW--GGQRCEGC 516
           P  Q  P  P +V   GPR   G       P    LPG   +A     D   G     G 
Sbjct: 692 PGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGT 751

Query: 517 GGGSQPFAGRRAERGKRG-AGVP 538
            G + P  G +   G+RG AG P
Sbjct: 752 PGDTGP-PGLQGMPGERGIAGTP 773



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 115/460 (25%), Positives = 147/460 (31%), Gaps = 72/460 (15%)

Query: 68   GPTRPSGSL-TTRRPRDAGEAAVSGPSRQRR---TSRARTALWGRRSRRAAGP-GLDCAG 122
            GP  P GS   +  P D G   + G   +R    T   +    G   + A G  G D A 
Sbjct: 738  GPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGAR 797

Query: 123  SAPAPSGAQSCGGPA-------PASALRRPLTQWDASGGGGRG-----SHSGPRA--GTP 168
              P P G     GP        P   +  P ++ +    G  G       +GP+   G P
Sbjct: 798  GLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQP 857

Query: 169  G-----GGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHG 223
            G     G    +  A    P  L       G +    G+    GG GT  PP A      
Sbjct: 858  GVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPN----GVPGLKGGRGTQGPPGAT----- 908

Query: 224  GAAGARAQVRGSEKRACPGSTLPPSSV-LAGCVGTRAR--GHGGVQRQRFSAPSSHSTSG 280
            G  G+  +V        PG   P       G  G R     HG V  +  + P       
Sbjct: 909  GFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDK 968

Query: 281  GRPTGERSSREPLLDPSKAARAS-----ALPTARVAHASP--PSLAAAQWRLG-----GG 328
            G P GE     P   P  A          +P  R     P  P  A    ++G     G 
Sbjct: 969  GDP-GEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGD 1027

Query: 329  KRKPTVLKGAVRTDLSTAEEEDPR----SGRALEPAQGSELWARAERHGGSSGARTLPTP 384
            K  P    G V    S     +P     +G    P +   +  R +R  G  G   LP  
Sbjct: 1028 KGPP----GPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDR--GDPGPAGLPG- 1080

Query: 385  SRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSG--RG----SGVTHSVGTHALATRRG 438
            S+  PG P P G+   A  RG  G  G     G    RG     G     G H     RG
Sbjct: 1081 SQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRG 1140

Query: 439  SRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRA-FGPR 477
             +  R    L+G+P       P P     S  +   FGPR
Sbjct: 1141 QKGHRGFTGLQGLP-----GPPGPNGEQGSAGIPGPFGPR 1175


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 101/443 (22%), Positives = 160/443 (36%), Gaps = 88/443 (19%)

Query: 69   PTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCAGSAPAPS 128
            P R SG   +R P   G +    P+R+ R SR+RT    RRS R+           PA  
Sbjct: 640  PARRSGRSRSRTPARRGRSRSRTPARRGR-SRSRTP--ARRSGRS-------RSRTPARR 689

Query: 129  GAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGG----RSSRAGARRKTPL 184
            G      P    +  R L +      G   S +  R G  G        SR   RR    
Sbjct: 690  GRSRSRTPRRGRSRSRSLVR-----RGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSN 744

Query: 185  SLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGST 244
            S   +K  + SSRR + L S          PR           ++A+ R S +R+  GS+
Sbjct: 745  SSPEMKKSRISSRRSRSLSS----------PR-----------SKAKSRLSLRRSLSGSS 783

Query: 245  LPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASA 304
             P     +     R+R      + +   P   S S   P  ++ S+     PS+ + +S+
Sbjct: 784  -PCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSK----TPSRQSHSSS 838

Query: 305  LPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSE 364
             P  +V   +PP                   +G++ +  +  +   P+     E +   E
Sbjct: 839  SPHPKVKSGTPPR------------------QGSITSPQANEQSVTPQRRSCFESSPDPE 880

Query: 365  LWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGRGSGV 424
            L +R       SG+      S   P +   R S+P  +++     + ++    S  GS  
Sbjct: 881  LKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVK-----AIISPRQRSHSGSSS 935

Query: 425  THSVGTHALATRRGSRAPRPVGVL--RGVPHF------RPLSSPAPQSPPRS-------- 468
                   +  T R SR+  P   +  R +P +       P +   P++PPR         
Sbjct: 936  PSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISP 995

Query: 469  -PSVRAF---GPRLGAGRLSCPQ 487
             P V+A    GP L   +  CPQ
Sbjct: 996  YPKVKAQTPPGPSLSGSKSPCPQ 1018



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 118/477 (24%), Positives = 167/477 (35%), Gaps = 63/477 (13%)

Query: 36   PEFPQIARNDCWDRVPRGSVTDSNHTPAGLDCGPTRP---SGSLTTRRPRDAGEAAVSGP 92
            P  P   R++C D  P         TP      P+ P   +  LT +R R   E++V   
Sbjct: 1470 PRTPSRGRSEC-DSSPEPKALPQ--TPRPRSRSPSSPELNNKCLTPQRERSGSESSVD-- 1524

Query: 93   SRQRRTSRARTALWGRRSRRAAGPGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDAS 152
                + + ART L G+RSR  +   LD   SA     ++S   P   +  R PL Q   S
Sbjct: 1525 ----QKTVARTPL-GQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRS 1579

Query: 153  GG----------GGRGSHSG--------PRAGTPG-GGRSSRAGARRKTPLSLCPLKLRK 193
            G             R S SG        PRA      G  S    +   P +L P + R 
Sbjct: 1580 GSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRAL-PRRSRS 1638

Query: 194  GSSRRCQG---LGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSV 250
            GSS + +G    GSS   S    PP++   R G  +    + +         S   P   
Sbjct: 1639 GSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELT 1698

Query: 251  LAGCVGTRARGHGGVQRQRFSAPSSH--STSGGRPTGERSSREPLLDPSKAARASALP-- 306
                +  R+R        R   P  H  S S   P     SR      S+  R+++ P  
Sbjct: 1699 RKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRS-----SRRRRSASSPRT 1753

Query: 307  --TARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSE 364
              T+R   +  P     Q      +R+ T  +   R D S + +    + R  + ++   
Sbjct: 1754 KTTSRRGRSPSPKPRGLQRSRSRSRREKT--RTTRRRDRSGSSQS---TSRRRQRSRSRS 1808

Query: 365  LWARAERHGGSSGARTLPTPSRARPGKPAPRG---SAPPARLRGGGGGSGLTQLVGSGRG 421
               R  R G    +R+      +R      RG   + P +R R     S         R 
Sbjct: 1809 RVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRA 1868

Query: 422  SGVTH--SVGTHALATRRGSRA-PRPVGVLR-----GVPHFRPLSSPAPQSPPRSPS 470
            S  TH  S     L +RR SR+   PV   R      V   R  S  +P S  RS S
Sbjct: 1869 SPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRS 1925



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 115/470 (24%), Positives = 160/470 (34%), Gaps = 55/470 (11%)

Query: 93  SRQRRTSRARTALWGRRSRRA-AGPGLDCAGSAPAP-SGAQSCGGPAPASAL--RRPLTQ 148
           S+ ++  R+R+     +SRRA      D A S+    S ++S       +AL  R P   
Sbjct: 240 SKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSP- 298

Query: 149 WDASGGGGRGSHSGPRAGTPGGGRSSRAGARRKTPLSLCPL------KLRKGSSRRCQGL 202
             ASG  G G       GT    R S      K P S  P       K  K ++R     
Sbjct: 299 --ASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSS--PYEDKDKDKKEKSATRPSPSP 354

Query: 203 GSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGH 262
             S  G   P P   L  RHGG+    A    S++   P S   P         TR R  
Sbjct: 355 ERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASP---------TRDRS- 404

Query: 263 GGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQ 322
                ++    SS  +S   P   + SR     P     A A  + R   +SP S   + 
Sbjct: 405 PPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSH 464

Query: 323 WRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEP--AQGSELWARAERHGGSSGART 380
                         G  + D S +     R GR+  P  A+     +R     G S +R+
Sbjct: 465 --------------GRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRS 510

Query: 381 LPTPSRARPGKPAPRGSAPPAR------LRGGGGGSGLTQLVGSGRGS--GVTHSVGTHA 432
            P   R+R  +   R  +P  R       R G   S  TQ  G  R +  G +HS    +
Sbjct: 511 -PQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHS---RS 566

Query: 433 LATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAGRLSCPQAPRAA 492
            ATR  SR+  P    R             ++P R  S      R G  R   P   R+ 
Sbjct: 567 PATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSR 626

Query: 493 ALPGI--AVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRGAGVPWR 540
               +     + SPA   G  R        +  +   A RG+  +  P R
Sbjct: 627 TRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPAR 676



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 104/447 (23%), Positives = 153/447 (34%), Gaps = 55/447 (12%)

Query: 69   PTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPG-LDCAGSAPAP 127
            PT  +   ++R P+    A + GP     T+    A  G R+  A  P  L  A  APA 
Sbjct: 2318 PTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIA--GSRTAAALAPASLTSARMAPAL 2375

Query: 128  SGAQSCGGPAPASALRR-------PLTQWDAS----GGGGRGSHSGPRAGTPGGGRSSRA 176
            SGA       P SA  R       PL     S        +   +  RA +P   R  +A
Sbjct: 2376 SGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSP-SSRMGQA 2434

Query: 177  GARRKTPLS----LCPLKLRKGSSRRC------QGLGSSWGGSGTPPPPRALWNRHGGAA 226
             ++   P +      P+        RC         GS    SG      +    H G  
Sbjct: 2435 PSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGML 2494

Query: 227  GARAQVRGSEKRACPGSTL--PPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPT 284
               A          P S +  PP+S  A      A      +R+  S+ SS S+S    +
Sbjct: 2495 SVPAP-------GVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSS 2547

Query: 285  GERSSREPLLDPSKAARASALPT---ARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRT 341
               SS       S  +  S+LP      +     P+ A  +    G   +PT  K   R+
Sbjct: 2548 SSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRS 2607

Query: 342  DLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPG-----KPAPRG 396
              S++      S  +   +  S   + +     SS + +  +PS A+PG     KPA   
Sbjct: 2608 SSSSSSSSSSSSSSSSSSSSSSSS-SSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPK 2666

Query: 397  SAPPARLRGGGGGSGLTQL----------VGSGRGSGVTHSVGTHALATRRGSRAPRPVG 446
              PP   R       +  L          V   R S         + ++ RGSR  +  G
Sbjct: 2667 KPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQR-G 2725

Query: 447  VLRGVPHFRPLSSPAPQSPPRSPSVRA 473
              R   H R   +P+P+ P R  S R+
Sbjct: 2726 DSRSPSHKRRRETPSPR-PMRHRSSRS 2751



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 109/480 (22%), Positives = 153/480 (31%), Gaps = 86/480 (17%)

Query: 90  SGPSRQRRTSRARTALWGRRSRRAAGPGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQW 149
           + P+R R   ++   L    S  ++ P       +   S +     PAPA    R ++  
Sbjct: 397 ASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSS 456

Query: 150 DASGGGGRG------SHSGPRAGTPGGGRS----SRAGARRKTPLSLCPLKLRKGSSRRC 199
             S     G      SHS   +   G  RS     R  +R +TP      + R    RR 
Sbjct: 457 PTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRS 516

Query: 200 QGLGSSWGGSGTPP-------PPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLA 252
           +     WG S +P        P R  W+R         Q RG  + A  G +   S    
Sbjct: 517 RS-AQRWGRSRSPQRRGRSRSPQRPGWSR-----SRNTQRRGRSRSARRGRSHSRSPATR 570

Query: 253 GCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVAH 312
           G             R R   P+    S  R    R SR            S  PT R + 
Sbjct: 571 G-------------RSRSRTPARRGRSRSRTPARRRSR------------SRTPTRRRSR 605

Query: 313 ASPPSLAAAQWRLGGGK-RKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAER 371
           +  P+      R G  + R P   +   R+ +        R  R+  PA          R
Sbjct: 606 SRTPA------RRGRSRSRTPARRRSRTRSPVR-------RRSRSRSPA----------R 642

Query: 372 HGGSSGARTLPTPSRARPGKPAPRG---SAPPARLRGGGGGSGLTQLVGSGRGSGVTHSV 428
             G S +RT     R+R   PA RG   S  PAR R G   S      G  R        
Sbjct: 643 RSGRSRSRTPARRGRSRSRTPARRGRSRSRTPAR-RSGRSRSRTPARRGRSRSRTPRRGR 701

Query: 429 GTHALATRRG---SRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAGRLSC 485
                  RRG   SR P+  G        +  S  + +    + S      R+ + R   
Sbjct: 702 SRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRS 761

Query: 486 PQAPRAAALPGIAV------LAPSPAHDWGGQRCEGCGGGSQPFA-GRRAERGKRGAGVP 538
             +PR+ A   +++       +P P             G SQP A  R   R  R +  P
Sbjct: 762 LSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSP 821


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 121/509 (23%), Positives = 161/509 (31%), Gaps = 69/509 (13%)

Query: 51   PRGSVTDSNHTPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRS 110
            P+G+ T    TP     GP  PS       P     +   GP        A  +  G  +
Sbjct: 936  PKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP--------ATPSPKGAPT 987

Query: 111  RRAAGPGLDCAGSA-PAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPG 169
              AA P     G A P+P GA +     P S    P       G       S P A TP 
Sbjct: 988  PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGA------STPPAATPP 1041

Query: 170  GGRSSRAG-----ARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGG 224
              + S A          TP +  P    KG        G+    + TPP P+      GG
Sbjct: 1042 SPKGSPAATPLPKGAPTTPAATLPSP--KGGPATPSLKGAPTPPAATPPSPK------GG 1093

Query: 225  AAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRAR-GHGGVQRQRFSAPSSHSTSGGRP 283
             A    +          G+ +PP++      G  A   H G      + P S       P
Sbjct: 1094 PATPSPK----------GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATP 1143

Query: 284  TGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDL 343
              + +   P   P       A P  + A  +P   AA      GG   P+  KGA  T  
Sbjct: 1144 PPKGAPTTPAATPPSPKGGLATPPPKGAPTTP---AATPPSPKGGLATPSP-KGAPTTPA 1199

Query: 344  STAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARL 403
            +T     P+ G A    +G+     A       G  T P+P     G P    + PP+  
Sbjct: 1200 AT--PPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT-PSPK----GAPTTPAATPPS-- 1250

Query: 404  RGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQ 463
                GG       G+      T       LAT     AP P  V    P   P +SP P+
Sbjct: 1251 --PKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP-PK 1307

Query: 464  SPPRSPSVRAFGPRLGAGRLSCPQAPRAAAL-----PGIAVLAPSPAHDWGGQRCEGCGG 518
              P  P+     P+   G      AP   A+      G   L  +     GG        
Sbjct: 1308 GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKE 1367

Query: 519  GSQPFAGRRAERG---------KRGAGVP 538
            G  P A   + +G         KRG  +P
Sbjct: 1368 GPTPPAATPSHKGGPAMTPPSPKRGPAIP 1396



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 122/487 (25%), Positives = 165/487 (33%), Gaps = 68/487 (13%)

Query: 51   PRGSVTDSNHTPAGLDCGPTRPS--GSLT---TRRPRDAGEAAVSGPSRQRRTSRARTAL 105
            P+G+ T    TP     GP  PS  G+ T      P   G  A +   +   T  A T  
Sbjct: 982  PKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPP 1041

Query: 106  WGRRSRRAAGPGLDCAGSAPAPSGAQSCGGPAPASALRRPL----TQWDASGGGGRGSHS 161
              + S  AA P    A + PA +     GGPA  S    P     T     GG    S  
Sbjct: 1042 SPKGSP-AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100

Query: 162  G---PRAGTPGGGRSSRAGARRK----TPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPP 214
            G   P A TP   +   A    K    TP +  P    KG        G+    + TPP 
Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP--KGGLATPPPKGAPTTPAATPPS 1158

Query: 215  PRALWNRHGGAAGARAQVRGSEKRACPGS------TLPPSSVLAGCVGTRARGHGGVQRQ 268
            P+      GG A    +   +   A P S      T  P         T     GG+   
Sbjct: 1159 PK------GGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212

Query: 269  R-FSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVA----HASPPSLAAAQW 323
                AP++ + +   P G  ++  P   P+  A     P    A      +P   AA   
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPP 1272

Query: 324  RLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPT 383
             L GG   P   KGA    + T     P+ G A  P +G+           +  A T P+
Sbjct: 1273 SLKGGLATPPH-KGAPNPAVVTPPS--PKGGPATSPPKGAP----------TPPAATPPS 1319

Query: 384  PSRARPGKPAPRGSAPPARLR--GGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRA 441
            P +  PG P P+G+  P  +      G   L     S +G   T S       ++ G   
Sbjct: 1320 P-KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS-------SKEGPTP 1371

Query: 442  PRPVGVLRGVPHFRPLSS------PAPQSPPRSPSVRAFGPRLGAGRLSCPQAPRAAALP 495
            P      +G P   P S       P+P+  P SP+V    P+      + P     AA P
Sbjct: 1372 PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAP---ATPVTREGAATP 1428

Query: 496  GIAVLAP 502
                L P
Sbjct: 1429 SKGDLTP 1435



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 116/506 (22%), Positives = 170/506 (33%), Gaps = 96/506 (18%)

Query: 51   PRGSVTDSNHTPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRS 110
            P+G+ T    TPA     P  P G L T  P+ A     + P   +    A  +  G  +
Sbjct: 1191 PKGAPT----TPAAT---PPSPKGGLATPSPKGAPTTPAATPPSPKG-GLATPSPKGAPT 1242

Query: 111  RRAAGPGLDCAGSA-PAPSGAQSCGGPAPAS---ALRRP----------LTQWDASGGGG 156
              AA P     G A P P GA +     P S    L  P          +T     GG  
Sbjct: 1243 TPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA 1302

Query: 157  RGSHSG---PRAGTPGGGRSSRAGARRK---TPLSLCPLKLRKGSSRRCQGLGSSWGGSG 210
                 G   P A TP   + S      K   TP ++ P    KG+        SS GG  
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS-PKGTPTLPATTPSSKGGPT 1361

Query: 211  TPP------PPRALWNRHGGAAGARAQVRGSEKR--ACPGSTLPPSSVLAGCVGTRARGH 262
            TP       PP A  +  GG A        S KR  A P     P+S     +  +    
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPA----MTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA 1417

Query: 263  GGVQRQRFSAPS------------------SHSTSGGRPTGERSSREPLLDPSKAARASA 304
              V R+  + PS                  + S   G P    S  +P L P+    +  
Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL-PAVTPPSPK 1476

Query: 305  LPTA--RVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLST-AEEEDPRSGRALEPAQ 361
             P A  +VA +S P  A A     G    P V+  + +   +T +   DP +  A   ++
Sbjct: 1477 EPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSK 1536

Query: 362  GSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGRG 421
             +     A +      A T+P+P +  P  P P+ +      +       +T        
Sbjct: 1537 KTPA-TLAPKEALIPPAMTVPSPKKT-PAIPTPKEAPATPSSKEASSPPAVTP------- 1587

Query: 422  SGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAG 481
                        +T +G+ +P+ + +   V      +SP+P+  P  P+V    P  G  
Sbjct: 1588 ------------STYKGAPSPKELLIPPAV------TSPSPKEAPTPPAVTPPSPEKG-- 1627

Query: 482  RLSCPQAPRAAALPGIAVLAPSPAHD 507
                P  P     P    + PS   D
Sbjct: 1628 ----PATPAPKGTPTSPPVTPSSLKD 1649


>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
          Length = 629

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 95/388 (24%), Positives = 128/388 (32%), Gaps = 62/388 (15%)

Query: 68  GPTRPSGSLTTRRPRDAGEAAVSGPS---RQRRTSRARTALWGRRSRRAAGPGLDCAGSA 124
           GP+ P G   + RP+  G+A+ S P     +    R+ +A +      +AGP    +   
Sbjct: 150 GPSEPRGIYASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGG-SAGPEACSSAER 208

Query: 125 PAPSGAQSCGGPAPASALR------RPLTQWDASGGGGR------------------GSH 160
            A +G      P  A A+R      RP T    +GG GR                  G  
Sbjct: 209 RARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQP 268

Query: 161 SGPRAGTPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWN 220
                G  GG R   +  +R    S  P   R       + +G      G P  P AL  
Sbjct: 269 RTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVG------GHPTSPAALSR 322

Query: 221 RHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSG 280
               +  + A     E  A P +  PP S   G +  +A+   G Q      P   +   
Sbjct: 323 AWASSWESEA---APEPAAPPAAPSPPDSPAEGRL-VKAQYIPGAQAATRGLPGRAARRK 378

Query: 281 GRPTGERSSRE---PLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKG 337
             P     S E   P   P  A R   +  A     SP +  A++       +  T L G
Sbjct: 379 PPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASR------SQSETSLLG 432

Query: 338 AVRTDLS------TAEEEDPRSGR---------ALEPAQGSELWARAERHGGSSGARTLP 382
                 S      TAE E+PR  R         A + A     W        + G R  P
Sbjct: 433 RASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRP 492

Query: 383 TPSRARPGKPAPRGSAPPARLRGGGGGS 410
               AR   P P  SAP  RL  G  GS
Sbjct: 493 RAPAARVPGPGPSPSAPQRRLLYGCAGS 520



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 99/402 (24%), Positives = 134/402 (33%), Gaps = 73/402 (18%)

Query: 132 SCGGP-APASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARRKTPLSLCPLK 190
           S GGP +P S              G  GS S  R G P   R   A  R K+     P  
Sbjct: 123 STGGPDSPPSTF--------CGDSGFSGSSSYGRLG-PSEPRGIYASERPKSLGDASP-- 171

Query: 191 LRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSV 250
               S+    G  ++   S + P P A     GG+AG  A    +E+RA  G  L PS +
Sbjct: 172 ----SAPEVVGARAAVPRSFSAPYPTA-----GGSAGPEA-CSSAERRARAGPFLTPSPL 221

Query: 251 LA---------GCVGTRARGHGGV-------------QRQRFSAPSSHSTSGGRPTGERS 288
            A         G   T +   GG              +R+R  A    ++ GG   G R 
Sbjct: 222 HAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRR 281

Query: 289 SREPLLDPSKAARA--SALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTA 346
                  P  A+ +  SA P      A  PSL     R+GG    P  L  A  +   + 
Sbjct: 282 QNSVRQRPPDASPSPGSARP------AREPSLE----RVGGHPTSPAALSRAWASSWESE 331

Query: 347 EEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGG 406
              +P +  A      S    R  +     GA+     +R  PG+ A R   P  R R  
Sbjct: 332 AAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAA---TRGLPGRAARRKPPPLTRGRSV 388

Query: 407 GGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPP 466
                  +   +GR   +  + G      RRGS   R     +        +S  P  PP
Sbjct: 389 EQSPPRERPRAAGRRGRMAEASG------RRGSPRARKASRSQSETSLLGRASAVPSGPP 442

Query: 467 RSPSVRAFGPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDW 508
           + P+     PR        P  PR    P +A  A      W
Sbjct: 443 KYPTAEREEPR--------PPRPRRGPAPTLAAQAAGSCRRW 476



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 67/265 (25%), Positives = 84/265 (31%), Gaps = 31/265 (11%)

Query: 270 FSAPSSHSTSG-GRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGG 328
           FS  SS+   G   P G  +S  P    S    + + P    A A+ P   +A +   GG
Sbjct: 140 FSGSSSYGRLGPSEPRGIYASERP---KSLGDASPSAPEVVGARAAVPRSFSAPYPTAGG 196

Query: 329 KRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRAR 388
              P     A         E   R+G  L P   S L A A R     G     +P    
Sbjct: 197 SAGPEACSSA---------ERRARAGPFLTP---SPLHAVAMRSPRPCGRPPTDSPDAGG 244

Query: 389 PGKPAPRG-SAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGV 447
            G+P     SA   R R  G G   T   G+  G              R+ S   RP   
Sbjct: 245 AGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGP------------RRQNSVRQRPPDA 292

Query: 448 LRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHD 507
                  RP   P+ +     P+  A   R  A       AP  AA P       SPA  
Sbjct: 293 SPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEG 352

Query: 508 --WGGQRCEGCGGGSQPFAGRRAER 530
                Q   G    ++   GR A R
Sbjct: 353 RLVKAQYIPGAQAATRGLPGRAARR 377


>gi|239752764 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 370

 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 99/376 (26%), Positives = 127/376 (33%), Gaps = 74/376 (19%)

Query: 178 ARRKTPLSLCPLKLRK--------GSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGAR 229
           A  ++P      +LR+        G  R C G G      G P            A GA 
Sbjct: 48  AHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRG----GLPG---------AAALGAG 94

Query: 230 AQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSS 289
           AQ     + A P  +  P  V  G    RA   GG  R+R   P   + + G P  E   
Sbjct: 95  AQQPRRRRLAQPPGSRAPLQV-GGAPRRRAHLTGGPPRRR---PPRLAAAHGLPASEAPG 150

Query: 290 REPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEE 349
             P  D ++      L +AR+    PP+ AA  WR G  + +P +L            + 
Sbjct: 151 LRP--DSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLL------------QP 196

Query: 350 DPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGG 409
            P     L  + G EL AR           +LP PS A P  P P   APPA        
Sbjct: 197 PPMLSPGLAQSPGVELHAR---------TLSLPAPSPA-PCLPPP---APPAARTPSAHS 243

Query: 410 SGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPH-----FRPLSSPAPQS 464
              T        +       T AL   RG     P  ++ G P          S PAP +
Sbjct: 244 PAHTHF------TLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPA 297

Query: 465 P-PRSPSVRAFGPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPF 523
           P P +   R+ G R GA  L    APRA          PS    W  +R        +P 
Sbjct: 298 PVPSTARARSPGARRGAREL----APRAGRR-----RQPSGRTSW-RRRARREQRDREPA 347

Query: 524 AGRRAERGKRGAGVPW 539
                 RG   AG  W
Sbjct: 348 VCGAWPRGSHAAGAGW 363



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 52/201 (25%), Positives = 62/201 (30%), Gaps = 45/201 (22%)

Query: 317 SLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSS 376
           S A   W LG         +  +R       E   +      PAQ S+   R  R G   
Sbjct: 11  SSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVI 70

Query: 377 GARTLPTPSRARPGKPAP----RGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHA 432
             R    P R R G P       G+  P R R                            
Sbjct: 71  VGRRRACPGRGRGGLPGAAALGAGAQQPRRRR---------------------------- 102

Query: 433 LATRRGSRAPRPVGVLRGVPHFRP--LSSPAPQSPPR------SPSVRAFGPRLGAGRLS 484
           LA   GSRAP  VG   G P  R      P  + PPR       P+  A G R  + R  
Sbjct: 103 LAQPPGSRAPLQVG---GAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTR 159

Query: 485 CPQAPRAAALPGIAVLAPSPA 505
                 +A LP    L P+PA
Sbjct: 160 LRLRLASARLP--RGLPPAPA 178


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 103/433 (23%), Positives = 142/433 (32%), Gaps = 73/433 (16%)

Query: 109 RSRRAAGPGLDCAGSAPAPSGAQSCGGPAPASALR----------RPLTQWDASGGGGRG 158
           R+  A  PGL      P P G+     P   +ALR          +PL +     GG   
Sbjct: 15  RTPAARAPGL----LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70

Query: 159 SHSGPRAG---------------TPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLG 203
             S PRAG                P  GR  RA   + T         R   + R   LG
Sbjct: 71  PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130

Query: 204 SSW----------GGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAG 253
                         G  T  P R+       +AGAR    G      PG+  P  +  + 
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSAL-----SAGARRDTSG----PTPGTPSPAMARRSR 181

Query: 254 CVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVAHA 313
             GT      G+ R   SA     T G R +   +S     +PS AAR        +   
Sbjct: 182 AAGTEV----GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237

Query: 314 SPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHG 373
           +  SL+++   L    R     +G  R     ++ + P+  +AL P Q +     A    
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK-PKGLQALRPPQVTPPRKDAAPAL 296

Query: 374 GSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHAL 433
           G   +  L TPS +     A +  APP              L  +   S +T  + T   
Sbjct: 297 GPLSSSPLATPSPS----AALQSQAPPT-------------LPATPHSSSLTCQLATPLP 339

Query: 434 ATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAF--GPRLGAGRLSCPQAPRA 491
                  AP  +  L   P   P  +      P   +  +F   P L       PQAP A
Sbjct: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 399

Query: 492 AALPGIAVLAPSP 504
            ALP +    PSP
Sbjct: 400 LALPPLQA-PPSP 411



 Score = 32.7 bits (73), Expect = 0.91
 Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 7/98 (7%)

Query: 436 RRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAGRLSCPQAPRAAALP 495
           + G+ A  P     G+   RP  SP P  P    ++R  G     GR   P A RA  + 
Sbjct: 9   KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK--PLAERAGGIG 66

Query: 496 GIAVLAPSPAHDWGGQRCEGCGG---GSQPFAGRRAER 530
           G  +  P  A   G  R  G       S+P A  R ER
Sbjct: 67  GATI--PESAPRAGPTRSAGTSSRNPASRPPASGRGER 102



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 66/262 (25%), Positives = 80/262 (30%), Gaps = 46/262 (17%)

Query: 111 RRAAGPGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGG 170
           RR   PG D + S P  + A + G P P S  R P +      G     HS     TP  
Sbjct: 587 RRPPTPGPDTSVSGPRLTLALAPGPPPPPS--RSPSS---TLSGPDLAGHSSSATSTPEE 641

Query: 171 GRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARA 230
            R   +G                             GG+   PPP A       AA +R 
Sbjct: 642 LRGYDSGPE---------------------------GGAAASPPPDAELAACHPAAWSRG 674

Query: 231 QVRGSEKRACPGSTLP------PSSVLAGCVGTRARGHGGVQRQ--RFSAPSSHSTSGGR 282
                  R  PG+ LP      P S    C      G               S  TSGG+
Sbjct: 675 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGK 734

Query: 283 PT----GERSSREPLLDPSKAARASALPTARVAHASPPS--LAAAQWRLGGGKRKPTVLK 336
                    SSR P           AL  + V H    +  LAAA+   GG    P   +
Sbjct: 735 AAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAE 794

Query: 337 GAVRTDLSTAEEEDPRSGRALE 358
           G   T  + A   D   GR  E
Sbjct: 795 GGGVTGGARAALSDAELGRWAE 816



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 130/543 (23%), Positives = 167/543 (30%), Gaps = 92/543 (16%)

Query: 63  AGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCAG 122
           AG + G  RP+ S   R P +    +VS  S    T  +  A    R R +AG GL    
Sbjct: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA----RRRPSAGGGLQRPA 238

Query: 123 S-----------APAPSGAQSCGGP-APA----------SALRRPLT---QWDASGGGGR 157
           S           +PA SG  + G P APA           ALR P     + DA+   G 
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298

Query: 158 GSHSGPRAGTPGGGRSSRAGARRK-TPLS-------LCPLKLRKGSSRRCQGLGSSWGGS 209
            S S     +P     S+A      TP S         PL L   S      L +     
Sbjct: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPP 358

Query: 210 GTPPP--------PRALWNRHGGAAGARAQVRGSEKRACPGSTLPP---------SSVLA 252
            TPP         P          +   + +     +A P   LPP         S  L+
Sbjct: 359 ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 418

Query: 253 GCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDP-SKAARASALPTARVA 311
                  +    +      AP S   S            P+  P S  A     P+A   
Sbjct: 419 PLATPSPQAPNALAVHLLQAPFSPPPS-----------PPVQAPFSPPASPPVSPSATPP 467

Query: 312 HASPPSLAAAQWRLGGGK-RKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAE 370
             +PPSLAA   ++       P +   A     +      P    A  P Q     A   
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 527

Query: 371 RHGGSSGARTLP-----TPSRARPGKP--APRGSAPPARLRGGGGGSGLTQLVGSGRGSG 423
                S   + P     +PS + P  P   P   APP         + L Q+  S   S 
Sbjct: 528 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL------AAPLLQVPPSPPASP 581

Query: 424 VTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRL---GA 480
                    L   R    P P   + G      L+   P  P RSPS    GP L    +
Sbjct: 582 T--------LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 633

Query: 481 GRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRGAGVPWR 540
              S P+  R          A SP  D     C        P A   A RG  GA +PW 
Sbjct: 634 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP-APPLAFRGAPGAPLPWP 692

Query: 541 TQT 543
             T
Sbjct: 693 PAT 695


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 119/451 (26%), Positives = 148/451 (32%), Gaps = 77/451 (17%)

Query: 113  AAGPGLDCAGSAPAPSGAQSCGGP-APASALRRPLTQWDASGGGGRGSHSGPRA--GTPG 169
            A  PGL      P P G +   GP  P  A   P  Q      GG GS  GP+   G PG
Sbjct: 689  AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGS-PGPKGDKGEPG 747

Query: 170  G----GRSSRAGARRKT-PLSLC-----PLKLRKGSSRRCQGLGSSWGGSGT-----PPP 214
            G    G   + G R  T P+        P    +G +    G+    G  G      PP 
Sbjct: 748  GPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPG 807

Query: 215  PRALWNRHGGAAGARAQVRGSEKRACPGSTLP--PSSVLAGCVGTRARGHGGVQRQRFSA 272
            P        GA G   +  G  +R  PG      P  V     G+   G  G        
Sbjct: 808  PAGF----PGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPG-------- 855

Query: 273  PSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKP 332
            P       G P G  ++  P       AR    P     +  PP  + +  +   G   P
Sbjct: 856  PQGVKGERGSPGGPGAAGFP------GARGLPGPPGSNGNPGPPGPSGSPGK--DGPPGP 907

Query: 333  TVLKGAVRTD-LSTAEEEDPRSGRALEP-AQGSELWARAERHGGSSGARTLPTPSRARPG 390
                GA  +  +S  + +  + G    P AQG           G +GAR L  P    PG
Sbjct: 908  AGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGP----PG 963

Query: 391  KPAPRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRG 450
             P PRGS  P  ++G  G                    G + L+  RG   P+ +  L G
Sbjct: 964  MPGPRGSPGPQGVKGESG------------------KPGANGLSGERGPPGPQGLPGLAG 1005

Query: 451  VPHFRPLSSPAPQS---PPRSPSVRAFGPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHD 507
                 P     P S   P R  S    G R   G    P AP A   PG     P P   
Sbjct: 1006 TAG-EPGRDGNPGSDGLPGRDGSPGGKGDR---GENGSPGAPGAPGHPG----PPGPVGP 1057

Query: 508  WGGQRCEGCGGGSQPFAGRRAERGKRGAGVP 538
             G     G  G + P AG     G RGA  P
Sbjct: 1058 AGKSGDRGESGPAGP-AGAPGPAGSRGAPGP 1087



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 123/481 (25%), Positives = 158/481 (32%), Gaps = 77/481 (16%)

Query: 122 GSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGG-GRSSRAGARR 180
           G    P  A   G P P  A+         SG  G+   SG R G PG  G     G + 
Sbjct: 201 GPPGEPGQAGPSGPPGPPGAI-------GPSGPAGKDGESG-RPGRPGERGLPGPPGIKG 252

Query: 181 KTPLSLCP-LKLRKGSSRR-----------CQGLGSSWGGSGTPPP--PRALWNRHG--- 223
              +   P +K  +G   R            +G     G +G P P  PR      G   
Sbjct: 253 PAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPG 312

Query: 224 --GAAGARAQ--VRGSEKRACPGSTLPPSSV-LAGCVGTRAR-------GHGGVQRQRFS 271
             GAAGAR     RGS+ +  PG   PP +    G  G +         G  G   QR  
Sbjct: 313 LPGAAGARGNDGARGSDGQ--PGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGE 370

Query: 272 -APSSHSTSGGRPTGERSSREP----LLDPSKAARASALPTARVAHASPPSLAAAQWRLG 326
             P  H+ + G P     +  P     + P+    A  L  AR       +  A   R G
Sbjct: 371 PGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGG 430

Query: 327 GGKRKPTVLKG----------AVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHG--- 373
            G+      KG          A    +  A+ ED + G   EP       A  ER     
Sbjct: 431 AGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGF 490

Query: 374 -GSSGARTLP-----TPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHS 427
            G +G   +P        R  PG   PRG+A      G  GG G+  + GS  G G    
Sbjct: 491 RGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGK 550

Query: 428 VGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAF-------GPRLGA 480
            G        G   P      RG P    +  P P+    +P            GP+   
Sbjct: 551 PGPPGSQGESGRPGPPGPSGPRGQPGV--MGFPGPKGNDGAPGKNGERGGPGGPGPQGPP 608

Query: 481 GR--LSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRG-AGV 537
           G+   + PQ P     PG       P    G Q   G GG      G+  E G +G AG 
Sbjct: 609 GKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGE-NGKPGEPGPKGDAGA 667

Query: 538 P 538
           P
Sbjct: 668 P 668



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 120/495 (24%), Positives = 151/495 (30%), Gaps = 78/495 (15%)

Query: 116  PGLD-CAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSS 174
            PGL   AG   +P      G P PA     P    +  G G RG+      G P G    
Sbjct: 785  PGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGP 844

Query: 175  RAGARRKTPLSLCPLKLRKGSSRR--------CQGLGSSWGGSGTPPPPRALWN--RHG- 223
              G+    P     +K  +GS            +GL    G +G P PP    +  + G 
Sbjct: 845  PGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGP 904

Query: 224  -------------GAAGARAQVRGSEKRACPGSTLPPSSV----LAGCVGTRA-RGHGGV 265
                         G +G +       ++  PG+  PP +     +AG  G R   G  G+
Sbjct: 905  PGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGM 964

Query: 266  QRQRFS-APSSHSTSGGRP-----TGERSSREPLLDPSKAARASALPTARVAHASPPSLA 319
               R S  P       G+P     +GER    P   P  A  A      R  +     L 
Sbjct: 965  PGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGE--PGRDGNPGSDGLP 1022

Query: 320  AAQWRLGG-GKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGA 378
                  GG G R      GA            P     + PA  S    R E        
Sbjct: 1023 GRDGSPGGKGDRGENGSPGA------PGAPGHPGPPGPVGPAGKSG--DRGESGPAGPAG 1074

Query: 379  RTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRG 438
               P  SR  PG   PRG       RG  G  G     G+    G     G        G
Sbjct: 1075 APGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPG 1134

Query: 439  SRAPR-PVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAGRLSCPQAPRAAALPGI 497
               PR PVG             P P  PP     R  G R   G    P  P     PG 
Sbjct: 1135 PAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNR--GERGSEGSPGHPGQPGPPGPPG- 1191

Query: 498  AVLAPSPAHDWGGQRCEGCGG-GSQPFAGRRAERGKRGAGVPW-----------RTQTLS 545
               AP P           CGG G+   AG   E  K G   P+             + ++
Sbjct: 1192 ---APGPC----------CGGVGAAAIAGIGGE--KAGGFAPYYGDEPMDFKINTDEIMT 1236

Query: 546  LLRRCSGALRELESP 560
             L+  +G +  L SP
Sbjct: 1237 SLKSVNGQIESLISP 1251



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 132/541 (24%), Positives = 168/541 (31%), Gaps = 102/541 (18%)

Query: 68  GPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCAGSAPAP 127
           GP  P G+     P + G   + G +  R    AR +       +   PG       P  
Sbjct: 297 GPMGPRGA-----PGERGRPGLPGAAGARGNDGARGS-----DGQPGPPGPPGTAGFPGS 346

Query: 128 SGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRA-----GTPGG-GRSSRAGARRK 181
            GA+   GPA +        Q    G  G     GP       G+PGG G    AG    
Sbjct: 347 PGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGA 406

Query: 182 TPLSLCPLKLRKGSSRRCQGLGSSWGGSGTP--------PPPRALWNRHG--GAAGARAQ 231
             L           +    GL    GG+G P        P PR      G  G  GA+ +
Sbjct: 407 PGLMGARGPPGPAGANGAPGLR---GGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGE 463

Query: 232 VRGSEKRACPGSTLPPSSVLAGCVGTRA----RGHGGVQRQRFSAPSSHSTSGGR----P 283
                K   PG   P ++ L G  G R     RG  G        P     +G R    P
Sbjct: 464 ---DGKDGSPGE--PGANGLPGAAGERGAPGFRGPAGPN----GIPGEKGPAGERGAPGP 514

Query: 284 TGERSSR-EPLLDPSKAARAS-ALPTARVAHAS-----PPSLAAAQWRLG-----GGKRK 331
            G R +  EP  D          +P +     S     PP       R G     G + +
Sbjct: 515 AGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQ 574

Query: 332 PTVL-----KGAVRTDLSTAEEEDPRS-GRALEPAQGSELWARAERH----GGSSGARTL 381
           P V+     KG         E   P   G    P +  E   +        GG  G    
Sbjct: 575 PGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGP 634

Query: 382 PTPS--------------RARPGKPAPRGSAPPARLRGGGGGS---------GLTQLVGS 418
           P P                 +PG+P P+G A      GG G +         GL    G 
Sbjct: 635 PGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGL 694

Query: 419 GRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFR-PLSSPAPQSPPRSPSVRAFGPR 477
             G+G     G    A   G         L+G+P  R  L SP P+     P     GP 
Sbjct: 695 RGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPG----GP- 749

Query: 478 LGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRGAGV 537
            GA  +     PR    P   +  P PA    G + EG   G    AG R   G+RG   
Sbjct: 750 -GADGVPGKDGPRGPTGP---IGPPGPAGQ-PGDKGEGGAPGLPGIAGPRGSPGERGETG 804

Query: 538 P 538
           P
Sbjct: 805 P 805



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 52/193 (26%), Positives = 64/193 (33%), Gaps = 37/193 (19%)

Query: 51   PRGSVTDSNHTPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTS-----RARTAL 105
            P G V  +  +    + GP  P+G+     P  AG     GP   R        R    +
Sbjct: 1051 PPGPVGPAGKSGDRGESGPAGPAGA-----PGPAGSRGAPGPQGPRGDKGETGERGAAGI 1105

Query: 106  WGRRSRRAAGPGLDCAGSAPAPSGAQ-SCGGPAPASALRRPLTQWDASGGGGRGSHSGPR 164
             G R      PG   A  +P P+G Q + G P PA   R P+      G  G   H GP 
Sbjct: 1106 KGHRGF----PGNPGAPGSPGPAGQQGAIGSPGPAGP-RGPVGPSGPPGKDGTSGHPGPI 1160

Query: 165  AGTPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGG 224
               P G R +R                     R  +G     G  G P PP A     GG
Sbjct: 1161 G--PPGPRGNR-------------------GERGSEGSPGHPGQPGPPGPPGAPGPCCGG 1199

Query: 225  AAGARAQVRGSEK 237
               A     G EK
Sbjct: 1200 VGAAAIAGIGGEK 1212



 Score = 32.7 bits (73), Expect = 0.91
 Identities = 41/155 (26%), Positives = 50/155 (32%), Gaps = 10/155 (6%)

Query: 380 TLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGS 439
           T PT      G   P+G   P  + G  G  G+    GS    G      +     +  S
Sbjct: 93  TAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYS 152

Query: 440 RAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAGRLSCPQAPRAAALPGIAV 499
                  V  GV        P P  PP  P     GP   +G    P +P     PG   
Sbjct: 153 PQYDSYDVKSGVAVGGLAGYPGPAGPPGPP-----GPPGTSGHPGSPGSPGYQGPPG--- 204

Query: 500 LAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRG 534
             P  A   G     G  G S P AG+  E G+ G
Sbjct: 205 -EPGQAGPSGPPGPPGAIGPSGP-AGKDGESGRPG 237


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 97/370 (26%), Positives = 121/370 (32%), Gaps = 61/370 (16%)

Query: 134  GGPAPASALRRPLTQWDASGGGG-------RGSHSGPRAGTPGGGRSSRAGARRKTPLSL 186
            GGP+P      P     A GGGG       R     PRA +      +R+G  RK PL  
Sbjct: 1053 GGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPL-- 1110

Query: 187  CPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLP 246
                      ++ +  G    G G PP P              A    SEK + P   +P
Sbjct: 1111 ---------VKQTKVEGEPQKGGGLPPAPSP--TSPASPQPPPAVAAPSEKNSIP---IP 1156

Query: 247  PSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALP 306
               + A    +  R   G   +         T GG   G   S  P + P   +  S +P
Sbjct: 1157 TIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPS-PSPVP 1215

Query: 307  TARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELW 366
            T     ASP   A   +    G      L GA R +     E   RS   L    G E  
Sbjct: 1216 TP----ASPSGPATLDFTSQFG----AALVGAARREGGWQNEARRRSTLFLSTDAGDE-- 1265

Query: 367  ARAERHGGSSGARTLPTPS-RARPGKPAPRG---SAPPARLRGGGGGSGL------TQLV 416
                  GG  G  T   P  R R  K    G   + P  RL   G G+G       ++  
Sbjct: 1266 -----DGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAY 1320

Query: 417  GSGRGSGVTHSV-----GTHALATRRGSRAPRPVGVLRGVPHFRPLSSP-----APQSPP 466
            G G GS    S        H L T +      P+G+       R L        APQ PP
Sbjct: 1321 GGGGGSSAFTSFLPPRPLVHPL-TGKALDPASPLGLALAARE-RALKESSEGGGAPQPPP 1378

Query: 467  RSPSVRAFGP 476
            R PS R   P
Sbjct: 1379 RPPSPRYEAP 1388



 Score = 37.0 bits (84), Expect = 0.048
 Identities = 106/448 (23%), Positives = 152/448 (33%), Gaps = 92/448 (20%)

Query: 121  AGSAPAPSGAQSCGGPAPASALRRPLTQWDA-----------SGGGGRGSHSGPRAGTPG 169
            A +APAP+  Q   GP P       + + D+           S      S S    G+ G
Sbjct: 1652 APAAPAPAAPQP--GPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAG 1709

Query: 170  GGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPP-----RALWNRHGG 224
            GG  + AG      L    +    G +         +GGS TP PP            G 
Sbjct: 1710 GGGGAGAGVASGPELLDTYVAYLDGQA---------FGGSSTPGPPYPPQLMTPSKLRGR 1760

Query: 225  AAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPT 284
            A GA   +R            P S  ++    T A   G +  +  S P +   +GG   
Sbjct: 1761 ALGASGGLRPGPSGGLRDPVTPTSPTVS---VTGAGTDGLLALRACSGPPTAGVAGG--- 1814

Query: 285  GERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKP-----TVLKGAV 339
                + EP + P     AS+LP   +     P        L G   +P       +K ++
Sbjct: 1815 --PVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPP--LPGPLAQPQASALATVKASI 1870

Query: 340  RTDLSTAEEE---DPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRG 396
             ++LS+  ++      +G AL  A+G         HGG+S               P    
Sbjct: 1871 ISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYV-------------PERTS 1917

Query: 397  SAPPARLRGGGGGSGLTQLVGS-------------GRGSGVTHSVGTHALATR-RGSRAP 442
            S    RL      S L++ V S               G+GV+ +      AT    S + 
Sbjct: 1918 SLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSS 1977

Query: 443  RPVGVLRGVPHFR--PLSSPAPQSPPRSPSVRAFGPRLGAGRLSCPQAPRAAALPGIAVL 500
                 L+GV      PL   AP     SPS+      L A       APR ++LP   +L
Sbjct: 1978 TSTRHLQGVEFEMRPPLLRRAP-----SPSL------LPASEHKVSPAPRPSSLP---IL 2023

Query: 501  APSPAH----DWGGQRCEGCGGGSQPFA 524
               P +    D  G    G GG + PFA
Sbjct: 2024 PSGPLYPGLFDIRGSPTGGAGGSADPFA 2051



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 59/225 (26%), Positives = 77/225 (34%), Gaps = 37/225 (16%)

Query: 206  WGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCV--GTRARGHG 263
            W G G  P P A    H G+AG       S+  A     LPP +  A         RG  
Sbjct: 1050 WRGGGPSPTPGAPSPSHHGSAGGGG--GSSQGPALRYFQLPPRAASAAMYVPARSGRGRK 1107

Query: 264  GVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQW 323
            G   ++          GG P            PS  + AS  P        PP++AA   
Sbjct: 1108 GPLVKQTKVEGEPQKGGGLPPA----------PSPTSPASPQP--------PPAVAAPSE 1149

Query: 324  RLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPT 383
            +       PT++  A  T  S+       S  A  P Q        E  GG  G  + P+
Sbjct: 1150 K--NSIPIPTIIIKAPSTS-SSGRSSQGSSTEAEPPTQ-------PEPTGGGGGGGSSPS 1199

Query: 384  PSRA-RPGKPAPRGSAPPARLRGGGGGSGLTQ----LVGSGRGSG 423
            P+ A  P  P+P     PA   G       +Q    LVG+ R  G
Sbjct: 1200 PAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREG 1244


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 106/413 (25%), Positives = 137/413 (33%), Gaps = 119/413 (28%)

Query: 132 SCGGPAPASALRR-----PLTQWDASGGGGRGSHSGPRAGTPG-----------GGRSSR 175
           SCGG  P+   R      PL   + S G G  S +GP   T G           GG  + 
Sbjct: 315 SCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAG 374

Query: 176 AGARRKTPLSLCP-LKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRG 234
            G     P+   P  K  KG      G G++ GG+  PPPPR+        A  + Q  G
Sbjct: 375 GGGGGYRPIIQSPGYKTGKG------GYGAAAGGATRPPPPRS-------TATPKCQSLG 421

Query: 235 SEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLL 294
                      P ++   G    +A G GG   Q +S        G +  G+        
Sbjct: 422 G----------PAAAYATG----KASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQ 467

Query: 295 DPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSG 354
           D SKA   S  P    +   PP LA  Q         P  L+G                 
Sbjct: 468 DLSKAPSYSGGPPQPPSGPPPPGLATCQ------SYSPDQLQG----------------- 504

Query: 355 RALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQ 414
             L   QG          G ++ ++ LPT   A P      G +P   L G GGG G + 
Sbjct: 505 -QLYGVQGEPY------PGPAAHSQGLPT---ASPSLSYSTGHSP--ALSGHGGGWGPSS 552

Query: 415 LVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAF 474
           L G G  S  +H +                          RPL     QSPP      A 
Sbjct: 553 LGGGGEAS-PSHII--------------------------RPL-----QSPP------AT 574

Query: 475 GPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDW--GGQRCEGCGGGSQPFAG 525
           G   G G    P    ++ L     LAP  A  +  G    +G G GS+  AG
Sbjct: 575 GRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAG 627


>gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 737

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 131/487 (26%), Positives = 174/487 (35%), Gaps = 94/487 (19%)

Query: 64  GLDCGPTRPSGSLTTRRPR--DAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCA 121
           G+D  P  P     TR+ R  D    A +GP          TA  G +SRR  G  L  A
Sbjct: 290 GVDAAPRAPE----TRQVRKVDGVNPAAAGPRG------GATACSGVQSRRPQGLALR-A 338

Query: 122 GSAPAPSGAQSCGGPAPASALR--RPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGAR 179
              PA   A         S     R +++ D S   G G  S  R+ +P G    RA  +
Sbjct: 339 TLLPAKRSADMRWNSGSCSHFHILRKVSRPDLSLLHGLGLRS--RSESPAGQCVLRASQQ 396

Query: 180 RKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRA 239
           R        ++L  G  ++      +W  +  P   +A   R   A  ARAQ      R 
Sbjct: 397 RG-------VRLEGGGRQQLVPSQVAWRAARAPGRHQAAVLRRRRARVARAQQLA---RL 446

Query: 240 CPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKA 299
             G  +     L   +  R       +R R SAP+        P+ +     P   P  A
Sbjct: 447 RVGHAVQAPQALQAQLHARLPS----RRARSSAPA--------PSAQGRCMTPARSPVAA 494

Query: 300 ARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAV---------RTDLSTAEEED 350
             A+ L  AR   A+  S A   W+ G G+R+P      +         R  L+  E + 
Sbjct: 495 REAARLRGARPGPAA--SAATRMWQ-GSGRRRPGPDPQELDPHCKLSFPRLPLTPTESQP 551

Query: 351 PRSGRALEPAQGSELWARAERHGGSSGARTL-----PTPSRARPGKPAPRGSAPPARLRG 405
           P     +E  +G    ARA    G    R L     P   RARPG      S  PA   G
Sbjct: 552 PSHNLFVEELRG----ARAALARGWMLPRALRRQLCPIDPRARPG------SVAPAAASG 601

Query: 406 GGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRP--VGVLRG-----VPHFRPLS 458
               S L     SGR + +  ++G H    RRG+ A RP   G  RG        FR ++
Sbjct: 602 SIESSSL-----SGRAARL--ALGKHRACLRRGTEAGRPRLAGERRGAGDGRARDFRRIA 654

Query: 459 SPAPQSPPRSPSVRAFG-PRLGAGRLSCPQAPRA------AAL-------PGIAVLAPSP 504
             APQ P    +    G PR G   L     P A      AAL       P     AP+ 
Sbjct: 655 LAAPQFPHLESNTLGRGRPRPGDWALQATDFPDATKPALGAALRRGPIVGPAAGFAAPAA 714

Query: 505 AHDWGGQ 511
             D G +
Sbjct: 715 ERDPGAE 721


>gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 737

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 131/487 (26%), Positives = 174/487 (35%), Gaps = 94/487 (19%)

Query: 64  GLDCGPTRPSGSLTTRRPR--DAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCA 121
           G+D  P  P     TR+ R  D    A +GP          TA  G +SRR  G  L  A
Sbjct: 290 GVDAAPRAPE----TRQVRKVDGVNPAAAGPRG------GATACSGVQSRRPQGLALR-A 338

Query: 122 GSAPAPSGAQSCGGPAPASALR--RPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGAR 179
              PA   A         S     R +++ D S   G G  S  R+ +P G    RA  +
Sbjct: 339 TLLPAKRSADMRWNSGSCSHFHILRKVSRPDLSLLHGLGLRS--RSESPAGQCVLRASQQ 396

Query: 180 RKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRA 239
           R        ++L  G  ++      +W  +  P   +A   R   A  ARAQ      R 
Sbjct: 397 RG-------VRLEGGGRQQLVPSQVAWRAARAPGRHQAAVLRRRRARVARAQQLA---RL 446

Query: 240 CPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKA 299
             G  +     L   +  R       +R R SAP+        P+ +     P   P  A
Sbjct: 447 RVGHAVQAPQALQAQLHARLPS----RRARSSAPA--------PSAQGRCMTPARSPVAA 494

Query: 300 ARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAV---------RTDLSTAEEED 350
             A+ L  AR   A+  S A   W+ G G+R+P      +         R  L+  E + 
Sbjct: 495 REAARLRGARPGPAA--SAATRMWQ-GSGRRRPGPDPQELDPHCKLSFPRLPLTPTESQP 551

Query: 351 PRSGRALEPAQGSELWARAERHGGSSGARTL-----PTPSRARPGKPAPRGSAPPARLRG 405
           P     +E  +G    ARA    G    R L     P   RARPG      S  PA   G
Sbjct: 552 PSHNLFVEELRG----ARAALARGWMLPRALRRQLCPIDPRARPG------SVAPAAASG 601

Query: 406 GGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRP--VGVLRG-----VPHFRPLS 458
               S L     SGR + +  ++G H    RRG+ A RP   G  RG        FR ++
Sbjct: 602 SIESSSL-----SGRAARL--ALGKHRACLRRGTEAGRPRLAGERRGAGDGRARDFRRIA 654

Query: 459 SPAPQSPPRSPSVRAFG-PRLGAGRLSCPQAPRA------AAL-------PGIAVLAPSP 504
             APQ P    +    G PR G   L     P A      AAL       P     AP+ 
Sbjct: 655 LAAPQFPHLESNTLGRGRPRPGDWTLQATDFPDATKPALGAALRRGPIVGPAAGFAAPAA 714

Query: 505 AHDWGGQ 511
             D G +
Sbjct: 715 ERDPGAE 721


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 96/393 (24%), Positives = 140/393 (35%), Gaps = 57/393 (14%)

Query: 56   TDSNHTPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAG 115
            + S H+      G T    S   +    +G+++  G      +  +     G  S ++ G
Sbjct: 1068 SSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG 1127

Query: 116  PGLDCAGSAPAPS-GAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAG----TPGG 170
             G   +GS  +PS G    G    +S+ +      ++SG G   S SG  +       G 
Sbjct: 1128 HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS 1187

Query: 171  GRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARA 230
            G SS  G              R G S R +  GSS G S            H G  G+ +
Sbjct: 1188 GHSSGYGQHGS----------RSGQSSRGERHGSSSGSSS-----------HYGQHGSGS 1226

Query: 231  QVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSR 290
            +      R   GS   PS           RG  G      S+   H +  GR     SSR
Sbjct: 1227 RQSSGHGRQGSGSGHSPS-----------RGRHGSGLGHSSSHGQHGSGSGR----SSSR 1271

Query: 291  EPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEED 350
             P    S++  +S     +    S  S A +Q   G G        G+     ST ++E 
Sbjct: 1272 GPY--ESRSGHSSVF--GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEG 1327

Query: 351  PRSGRAL---EPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGG 407
              +G++        GS   +   RHG  SG     +PSR R G     GS   +     G
Sbjct: 1328 SSTGQSSSYGHRGSGSSQSSGYGRHGAGSG----QSPSRGRHGS----GSGHSSSYGQHG 1379

Query: 408  GGSGLTQLVG-SGRGSGVTHSVGTHALATRRGS 439
             GSG +   G  G GSG +   G H  ++ + S
Sbjct: 1380 SGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1412



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 80/337 (23%), Positives = 122/337 (36%), Gaps = 47/337 (13%)

Query: 107  GRRSRRAAGPGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAG 166
            G  S +++G G   +GS  +P   Q   G   + +  R         G GR S SG    
Sbjct: 2046 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH------GSGSGRSSSSGQHG- 2098

Query: 167  TPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAA 226
             PG G SS  G    +             S    G  S +G  G+     +   RHG ++
Sbjct: 2099 -PGLGESSGFGHHESSSGQSSSYSQHGSGS----GHSSGYGQHGSRSGQSSRGERHGSSS 2153

Query: 227  GARAQV--RGSEKRACPGSTLPPSSVLAGCVGTRARGHG-GVQRQRFSAPSSHSTSGGRP 283
            G+ ++    GS  R   G             G +  G G    R R  + S HS+S G+ 
Sbjct: 2154 GSSSRYGQHGSGSRQSSGH------------GRQGSGSGHSPSRGRHGSGSGHSSSHGQH 2201

Query: 284  TGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDL 343
             G  S R     P ++    +    +    S  S A +Q   G G        G+     
Sbjct: 2202 -GSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS 2260

Query: 344  STAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARL 403
            ST ++E   +G++    Q     +++  +G   G+ +  +PSR R G             
Sbjct: 2261 STFDQEGSSTGQSSSHGQHGSGSSQSSSYG-QQGSGSGQSPSRGRHGS------------ 2307

Query: 404  RGGGGGSGLTQLVGS-GRGSGVTHSVGTHALATRRGS 439
                 GSG +   G  G GSG + S G H   + + S
Sbjct: 2308 -----GSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS 2339



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 115/504 (22%), Positives = 173/504 (34%), Gaps = 80/504 (15%)

Query: 53  GSVTDSNHTPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRR--- 109
           GS   S ++  G   G +   G    +    +G+A+ SG   Q  +S  +++ +G+    
Sbjct: 354 GSGQSSGYSKHGSGSGHSSSQG----QHGSTSGQASSSG---QHGSSSRQSSSYGQHESA 406

Query: 110 SRRAAGPGLDCAGSAPAPSGAQ--SCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGT 167
           SR ++G G   +GS  +P   Q  S  G +P+S             G GR S SGP    
Sbjct: 407 SRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQH--------GTGFGRSSSSGPYVS- 457

Query: 168 PGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAG 227
            G G SS  G               + SS    G      GSG          +HG  +G
Sbjct: 458 -GSGYSSGFGHH-------------ESSSEHSSGYTQHGSGSGHSSGH----GQHGSRSG 499

Query: 228 ARAQVRGSEKRACPGSTLPPSSVLAGC---VGTRARGHGGVQ-----RQRFSAPSSHSTS 279
             +  RG  + +  GS+       +G    +G    G G  Q     R R  + S  S+S
Sbjct: 500 QSS--RGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSS 557

Query: 280 GGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAV 339
            G P G  S R     P ++    +         S  S    Q     G        G+ 
Sbjct: 558 YG-PHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGST 616

Query: 340 RTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAP 399
               S+  +    SG++    Q     +++ R+G   G+ +  +PSR R G         
Sbjct: 617 SGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYG-QQGSGSGQSPSRGRHGSDF------ 669

Query: 400 PARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSS 459
                  G  S   Q    G GSG + S G H   + + S      G  +   +     S
Sbjct: 670 -------GHSSSYGQ---HGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGY-----S 714

Query: 460 PAPQSPPRSPSVRAFGPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGG 519
                   S   R  G R G    S  Q   ++ L        S +H   G   +G G G
Sbjct: 715 QHGSGSSHSSGYRKHGSRSGQSSRS-EQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSG 773

Query: 520 SQP-------FAGRRAERGKRGAG 536
             P        +G  +  G+ G+G
Sbjct: 774 HSPSRVRHGSSSGHSSSHGQHGSG 797



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 87/388 (22%), Positives = 139/388 (35%), Gaps = 47/388 (12%)

Query: 56   TDSNHTPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAG 115
            + S H+      G T    S   +    +G+++  G      +  +     G  S ++ G
Sbjct: 1538 SSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG 1597

Query: 116  PGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSR 175
             G   +GS  +PS  +   G   +S+            G G G  SG        G+SS 
Sbjct: 1598 HGQRGSGSRQSPSYGRHGSGSGRSSS--------SGQHGSGLGESSGFGHHESSSGQSSS 1649

Query: 176  AGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGS 235
                            + GS     G  S +G  G+     +   RHG ++      R S
Sbjct: 1650 YS--------------QHGSG---SGHSSGYGQHGSRSGQSSRGERHGSSS------RSS 1686

Query: 236  EKRACPGSTLPPSSVLAGCVGTRARGHGGVQ---RQRFSAPSSHSTSGGRPTGERSSREP 292
             +    GS    SS      G   +G G  Q   R R  +   HS+S G+  G  S R  
Sbjct: 1687 SRYGQHGSGSRQSS------GHGRQGSGSGQSPSRGRHGSGLGHSSSHGQ-HGSGSGRSS 1739

Query: 293  LLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPR 352
               P ++    +    +    S  S A +Q   G G        G+     ST ++E   
Sbjct: 1740 SRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSS 1799

Query: 353  SGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGL 412
            +G++    Q     +++  + G  G+ +  +PSR R G     GS   +     G GSG 
Sbjct: 1800 TGQSSSHGQHGSGSSQSSSY-GQQGSGSGQSPSRGRHGS----GSGHSSSYGQHGSGSGW 1854

Query: 413  TQLVG-SGRGSGVTHSVGTHALATRRGS 439
            +   G  G GSG +   G H  ++ + S
Sbjct: 1855 SSSSGRHGSGSGQSSGFGHHESSSWQSS 1882



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 99/397 (24%), Positives = 141/397 (35%), Gaps = 53/397 (13%)

Query: 71   RPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCAGSAPAPSGA 130
            R SGS  +      G  +   PSR R          G  S  ++  G   +GS  + S  
Sbjct: 1339 RGSGSSQSSGYGRHGAGSGQSPSRGRH---------GSGSGHSSSYGQHGSGSGWSSSSG 1389

Query: 131  QSCGGPAPASAL-RRPLTQWDASG----GGGRGSHSGPRAGTPGGGRSSRAGARRKTPLS 185
            +   G   +S       + W +SG    G G G  S         G+SSR G R  +   
Sbjct: 1390 RHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSR-GERHGSSSG 1448

Query: 186  LCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQV----RGSEKRACP 241
                  + GS  R Q LG    GSG+   P     RHG  +G  +       GS   +  
Sbjct: 1449 SSSSYGQHGSGSR-QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSR 1507

Query: 242  GSTLPPSSVLAGCVGTRAR-GHGGVQRQRFSAPSSHSTSG--GRPTGERSSREPLLDPSK 298
            G     SS  +G     +R G      Q  S+    ST G  G  +G+ SS        +
Sbjct: 1508 GPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS------CGQ 1561

Query: 299  AARASALPTARVAHASPPSLAAAQWRLGGGKRKPT--VLKGAVRTDLSTAEEEDPRSGRA 356
               +S   ++   H S  S ++   R G G  +      +G+      +       SGR+
Sbjct: 1562 HGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRS 1621

Query: 357  LEPAQ-GSELWARA---------------ERHGGSSGARTLPTPSRARPGKPA---PRGS 397
                Q GS L   +                +HG  SG  +      +R G+ +     GS
Sbjct: 1622 SSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGS 1681

Query: 398  APPARLRGGGGGSGLTQLVGSGR---GSGVTHSVGTH 431
            +  +  R G  GSG  Q  G GR   GSG + S G H
Sbjct: 1682 SSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRH 1718



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 90/374 (24%), Positives = 131/374 (35%), Gaps = 53/374 (14%)

Query: 56   TDSNHTPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAG 115
            + S H+      G T    S   +    +G+++  G      +  +     G  S ++ G
Sbjct: 2478 SSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG 2537

Query: 116  PGLDCAGSAPAPS-GAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAG----TPGG 170
             G   +GS  +PS G    G    +S+ +      ++SG G   S SG  +       G 
Sbjct: 2538 HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS 2597

Query: 171  GRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARA 230
            G SS  G              R G S R +  GSS G S            H G  G+ +
Sbjct: 2598 GHSSGYGQHGS----------RSGQSSRGERHGSSSGSSS-----------HYGQHGSGS 2636

Query: 231  QVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSR 290
            +      R   GS   PS           RG  G      S+   H +  GR     SSR
Sbjct: 2637 RQSSGHGRQGSGSGQSPS-----------RGRHGSGLGHSSSHGQHGSGSGR----SSSR 2681

Query: 291  EPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEED 350
             P    S+   +S     +    S  S A +Q   G G        G+     ST ++E 
Sbjct: 2682 GPY--ESRLGHSSVF--GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEG 2737

Query: 351  PRSGRAL---EPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGG 407
              +G++        GS   +   RHG  SG     + S  R G  + + S+      G G
Sbjct: 2738 SSTGQSSSYGHRGSGSSQSSGYGRHGAGSG----QSLSHGRHGSGSGQSSSYGQHGSGSG 2793

Query: 408  GGSGLTQLVGSGRG 421
              SG +Q  GSG G
Sbjct: 2794 QSSGYSQ-HGSGSG 2806



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 104/457 (22%), Positives = 154/457 (33%), Gaps = 80/457 (17%)

Query: 22  SLGEKALTALSHQNPEFPQIARNDCWDRVPRGSVTDSNHTPAGLDCGPTRPSGSLTTRRP 81
           SLG     + S Q+P  P   R++       GS   S++ P G        SG  ++R P
Sbjct: 527 SLGHSRHGSGSGQSPS-PSRGRHES------GSRQSSSYGPHGYG------SGRSSSRGP 573

Query: 82  RDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCAGSAPAPSG-AQSCGGPAPAS 140
            ++G    SG   Q   S  +++ +G+    +        G   + SG + SCG     S
Sbjct: 574 YESGSGHSSGLGHQESRS-GQSSGYGQHGSSSGHSSTH--GQHGSTSGQSSSCGQHGATS 630

Query: 141 ALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQ 200
                  Q  + G  G GS    R G  G G        R              SS    
Sbjct: 631 G------QSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGS------DFGHSSSYGQH 678

Query: 201 GLGSSWGGSGTP----------------PPPRALWNRHGGAA---------GARAQVRGS 235
           G GS W  S  P                    + +++HG  +         G+R+     
Sbjct: 679 GSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSR 738

Query: 236 EKRACPGSTLPPSSVLAGCVGTRARGHG--------GVQRQRFSAPSSHSTSGGRP-TGE 286
            ++    S L  S    G    ++ GHG           R R  + S HS+S G+  +G 
Sbjct: 739 SEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGT 798

Query: 287 RSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTA 346
             S       S + +AS        H S      +Q     G        G+     S++
Sbjct: 799 SCSSSCGHYESGSGQASGFGQ----HESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSS 854

Query: 347 EEEDPRSGRALEPAQGSELWARAE---RHG---------GSSGARTLPTPSRARPGKPAP 394
            + D  SG++    Q       A    RHG         G  G+ +  +PS  R G  + 
Sbjct: 855 GQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSG 914

Query: 395 RGSAPPARLRGGGGGSGLTQLVGSGRGSGVT-HSVGT 430
           R S+      G G  SG      SG+ SG T H  G+
Sbjct: 915 RSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGS 951



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 85/341 (24%), Positives = 120/341 (35%), Gaps = 46/341 (13%)

Query: 99   SRARTALWGRRSRRAAGPGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRG 158
            S +R    G  SR+++G G   +GS  +PS  +   G   +S      +      G GR 
Sbjct: 2155 SSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSS------SHGQHGSGSGRS 2208

Query: 159  SHSGP---RAGTPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPP 215
            S  GP   R+G         +G+   +  S    +   GS   C     S G  G+    
Sbjct: 2209 SSRGPYESRSGHSSVFGQHESGSGHSSAYS----QHGSGSGHFC-----SQGQHGSTSGQ 2259

Query: 216  RALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHG-GVQRQRFSAPS 274
             + +++ G + G       S      GS    SS      G +  G G    R R  + S
Sbjct: 2260 SSTFDQEGSSTGQ------SSSHGQHGSGSSQSS----SYGQQGSGSGQSPSRGRHGSGS 2309

Query: 275  SHSTS-GGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPT 333
             HS+S G   +G   S       S + ++S         +S  S    Q   G G     
Sbjct: 2310 GHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGF--GHHESSSWQSSGYTQHGSGSGHSSSY 2367

Query: 334  VLKGAVRTDLSTAEEEDPRSGRALEPAQ---GSELWARAERHGGSSGARTLPTPSRARPG 390
               G+     S  E     SG +    Q   GS       +HG  SG    P+PSR R G
Sbjct: 2368 EQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQS--PSPSRGRHG 2425

Query: 391  KPAPRGSAPPARLRGGGGGSGLTQL-----VGSGRGSGVTH 426
                 GS   +     G GSG +        GSG  SG+ H
Sbjct: 2426 S----GSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGH 2462



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 89/391 (22%), Positives = 132/391 (33%), Gaps = 45/391 (11%)

Query: 73   SGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCAGSAPAPSGAQS 132
            SGS  +      G  +   PSR R          G  S  ++  G   +GS  + S  + 
Sbjct: 2281 SGSSQSSSYGQQGSGSGQSPSRGRH---------GSGSGHSSSYGQHGSGSGWSSSSGRH 2331

Query: 133  CGGPAPASAL-RRPLTQWDASG----GGGRGSHSGPRAGTPGGGRSSRAGARRKTPLSLC 187
              G   +S       + W +SG    G G G  S         G+SSR G R  +     
Sbjct: 2332 GSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR-GERHGSSSGSS 2390

Query: 188  PLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPP 247
                + GS  R Q LG    GSG+   P     RHG  +G  +        +   S+  P
Sbjct: 2391 SSYGQHGSGSR-QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGP 2449

Query: 248  SSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPT-----GERSSREPLLDPSKAARA 302
                +G   +   GH   +  + S    H +S G  +     G  S +        A+  
Sbjct: 2450 YE--SGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSG 2507

Query: 303  SALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQ- 361
             +    +    S  S    +   G G+      +G+      +       SGR+    Q 
Sbjct: 2508 QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH 2567

Query: 362  GSELWARA---------------ERHGGSSGARTLPTPSRARPGKPA---PRGSAPPARL 403
            GS L   +                +HG  SG  +      +R G+ +     GS+  +  
Sbjct: 2568 GSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSS 2627

Query: 404  RGGGGGSGLTQLVGSGR---GSGVTHSVGTH 431
              G  GSG  Q  G GR   GSG + S G H
Sbjct: 2628 HYGQHGSGSRQSSGHGRQGSGSGQSPSRGRH 2658



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 102/480 (21%), Positives = 159/480 (33%), Gaps = 85/480 (17%)

Query: 93  SRQRRTSRARTALWGRR---SRRAAGPGLDCAGSAPAPSGAQSCGGPAPASA-------- 141
           S Q  +   +++ +G +   S +++G G   +GS  +P+  Q   G   +S+        
Sbjct: 166 SGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGS 225

Query: 142 ------LRRPLTQWDASGGGGRGSHSGPRAGT----PGGGRSSRAGARRKTPLSLCPLKL 191
                  +   +   +SG    GS SG  +G        G+SSR G R ++         
Sbjct: 226 GQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSR-GERHRSSSGSSSSYG 284

Query: 192 RKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVL 251
           + GS  R Q LG    GSG+   P  +  RHG  +G       S      GS        
Sbjct: 285 QHGSGSR-QSLGHGRQGSGSRQSPSHV--RHGSGSG------HSSSHGQHGS-------- 327

Query: 252 AGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVA 311
            G   + +RGH      + S    H +  G+ +G           SK    S   +++  
Sbjct: 328 -GSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGY----------SKHGSGSGHSSSQGQ 376

Query: 312 HASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAER 371
           H S    A++  + G   R+ +           ++      SG    P  G        +
Sbjct: 377 HGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHG--------Q 428

Query: 372 HGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGS----------GRG 421
            G  SG     +PS  + G    R S+    + G G  SG      S          G G
Sbjct: 429 RGSGSG----QSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSG 484

Query: 422 SGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAG 481
           SG +   G H   + + SR  R          +    S + QS   S        R G+G
Sbjct: 485 SGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHS--------RHGSG 536

Query: 482 RLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEG-----CGGGSQPFAGRRAERGKRGAG 536
               P   R     G    +    H +G  R         G G     G +  R  + +G
Sbjct: 537 SGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSG 596



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 88/402 (21%), Positives = 136/402 (33%), Gaps = 46/402 (11%)

Query: 68   GPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCAGSAPAP 127
            G T    S + +    +G+++  G         +     G  S ++ G G   +GS  +P
Sbjct: 845  GSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSP 904

Query: 128  SGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAG-TPGG---------------- 170
            S  +   G   +S+  R  +    S G G  S SG  +G T  G                
Sbjct: 905  SYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRS 964

Query: 171  GRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARA 230
            G+SSR+     +  S          SR  Q LG    GSG+   P     RHG  +G  +
Sbjct: 965  GQSSRSEQHGSSSGSSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSS 1022

Query: 231  QVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPT-----G 285
                   R+  G +       +G   +   GH   +  + S    H +S G  +     G
Sbjct: 1023 SY--GPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG 1080

Query: 286  ERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLST 345
              S +        A+   +    +    S  S    +   G G+      +G+      +
Sbjct: 1081 STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 1140

Query: 346  AEEEDPRSGRALEPAQ-GSELWARA---------------ERHGGSSGARTLPTPSRARP 389
                   SGR+    Q GS L   +                +HG  SG  +      +R 
Sbjct: 1141 YGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS 1200

Query: 390  GKPA---PRGSAPPARLRGGGGGSGLTQLVGSGR-GSGVTHS 427
            G+ +     GS+  +    G  GSG  Q  G GR GSG  HS
Sbjct: 1201 GQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHS 1242



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 81/344 (23%), Positives = 127/344 (36%), Gaps = 31/344 (9%)

Query: 90  SGPSRQRRTSRARTALWGRR---SRRAAGPGLDCAGSAPAPSGAQSCGGPAPASALRRPL 146
           S    + R+S   ++ +G+    SR++ G G   +GS  +PS  +   G   +S+  +  
Sbjct: 267 SSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHG 326

Query: 147 TQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSW 206
           +   +S    RG +      T G G+   +G+ + +  S      + GS     G  SS 
Sbjct: 327 S--GSSYSYSRGHYESGSGQTSGFGQ-HESGSGQSSGYS------KHGSG---SGHSSSQ 374

Query: 207 GGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQ 266
           G  G+     +   +HG ++   +     E  +   S     S  +G    ++ GHG  Q
Sbjct: 375 GQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSG----QSPGHG--Q 428

Query: 267 RQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLG 326
           R   S  S  S   G   G  SS  P +  S  +       +   H+S       Q   G
Sbjct: 429 RGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSS----GYTQHGSG 484

Query: 327 GGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQ---GSELWARAERHGGSSGARTLPT 383
            G        G+     S  E +   +G +    Q   GS       RHG  SG    P+
Sbjct: 485 SGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQS--PS 542

Query: 384 PSRARPGKPAPRGSAPPARLRGGGGGSGLTQL-VGSGRGSGVTH 426
           PSR R    + + S+      G G  S       GSG  SG+ H
Sbjct: 543 PSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGH 586



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 80/345 (23%), Positives = 114/345 (33%), Gaps = 61/345 (17%)

Query: 107  GRRSRRAAGPGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAG 166
            G  SR+++G G   +GS  +PS  +                      G G G  S     
Sbjct: 1223 GSGSRQSSGHGRQGSGSGHSPSRGRH---------------------GSGLGHSSSHGQH 1261

Query: 167  TPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAA 226
              G GRSS  G          P + R G S      G    GSG      + +++HG  +
Sbjct: 1262 GSGSGRSSSRG----------PYESRSGHS---SVFGQHESGSGHS----SAYSQHGSGS 1304

Query: 227  GARAQVRGSEKRACPGSTLPPSSVLAGCVGTRA-RGHGGVQRQ---RFSAPSSHSTSGGR 282
            G           +   ST        G   +   RG G  Q     R  A S  S S GR
Sbjct: 1305 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGR 1364

Query: 283  PTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTD 342
              G  S          +    +  + R    S  S           +       G+    
Sbjct: 1365 H-GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGH 1423

Query: 343  LSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTL----PTPSRARPGKP---APR 395
             S+ E+   RSG++          +R ERHG SSG+ +      + SR   G     +  
Sbjct: 1424 SSSYEQHGSRSGQS----------SRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1473

Query: 396  GSAP-PARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGS 439
            G +P P+R R G G    +     G GSG + S G +   +   S
Sbjct: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSS 1518


>gi|239750121 PREDICTED: hypothetical protein XP_002347280 [Homo
           sapiens]
          Length = 402

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 95/365 (26%), Positives = 117/365 (32%), Gaps = 66/365 (18%)

Query: 120 CAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGG--------GRGSHSGPRA-GTPGG 170
           C G    PS      GP    A RRP       GGG          GSH+ P   G PG 
Sbjct: 35  CCGRRSLPS----VSGPVRGRAERRPARGKHVRGGGVGGCRDSRAGGSHAAPSGLGVPGD 90

Query: 171 GRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPR--ALWNRHGGAAGA 228
             S+        P SL  + +  G + R     +S   +G  PP R  A  +   GA+  
Sbjct: 91  SESALGLLEPGPPKSL-RISVTLGQAPRAGPSAASSAAAGKTPPSRVPAEPSSRRGASKR 149

Query: 229 RAQVRGSEKR-----ACPGSTLPPSSVL----AGCVGTRARGHGGVQRQRFSAPSSHSTS 279
           R   R   +R      C G+   P + L     G       G    +R +     S S S
Sbjct: 150 RESWRTDGERLRSGRGCAGAARGPDASLDTRREGWPRAAVVGRHEARRLKPGVSVSSSLS 209

Query: 280 GGRPTGERSS-REPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVL--- 335
            G P    SS  E L        A A   A    A+PP    + W L      PT L   
Sbjct: 210 PGPPLQRSSSLNETLRGRRPPGPAPAAAGATRGTAAPPGRDPSAWFLDSASACPTPLAAR 269

Query: 336 --------------KGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTL 381
                         KGA        E       RA EP  G E      R       +T 
Sbjct: 270 SWHPFVANKLCGRGKGAGGGASRPKEGVGSGRARAWEPRGGRESGRSRRRKSLLEDLQTE 329

Query: 382 PT--PSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGS 439
            T  PSR  P +P+ R S P                    +G   TH+    A   R  +
Sbjct: 330 ATLWPSREVPREPS-RPSCP--------------------QGVAETHTTAERAQLRRLAA 368

Query: 440 RAPRP 444
           RAPRP
Sbjct: 369 RAPRP 373



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 58/225 (25%), Positives = 76/225 (33%), Gaps = 17/225 (7%)

Query: 232 VRG-SEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSR 290
           VRG +E+R   G  +    V  GC  +RA G             S S  G    G   S 
Sbjct: 48  VRGRAERRPARGKHVRGGGV-GGCRDSRAGGSHAAPSGLGVPGDSESALGLLEPGPPKSL 106

Query: 291 EPLLDPSKAARAS-ALPTARVAHASPPSLAAAQ--WRLGGGKRKPTVLKGAVRTDLSTAE 347
              +   +A RA  +  ++  A  +PPS   A+   R G  KR+ +      RTD     
Sbjct: 107 RISVTLGQAPRAGPSAASSAAAGKTPPSRVPAEPSSRRGASKRRESW-----RTDGERLR 161

Query: 348 EEDPRSGRALEPAQG----SELWARAERHGGSSGARTLP---TPSRARPGKPAPRGSAPP 400
                +G A  P        E W RA   G     R  P     S   PG P  R S+  
Sbjct: 162 SGRGCAGAARGPDASLDTRREGWPRAAVVGRHEARRLKPGVSVSSSLSPGPPLQRSSSLN 221

Query: 401 ARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPV 445
             LRG           G+ RG+         A      S  P P+
Sbjct: 222 ETLRGRRPPGPAPAAAGATRGTAAPPGRDPSAWFLDSASACPTPL 266


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 102/405 (25%), Positives = 136/405 (33%), Gaps = 66/405 (16%)

Query: 60  HTPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLD 119
           H   G   G  R SGS   R P  +G +    P R   + +   A  GR     + P   
Sbjct: 282 HRDEGRKTGSQRSSGS---RSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKP 338

Query: 120 ----------CAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPG 169
                      A +AP P  A+    P+P SA         A+GG GR      R     
Sbjct: 339 SSPSPRVRDKAAAAAPTPP-ARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSR 397

Query: 170 GGRSS--RAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTP-PPPRALWNRHGGAA 226
              S+  R G RR  P    P +    S  R +    S  G G P P P     R  G  
Sbjct: 398 SSASAPRRRGRRRPRP---APPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGH 454

Query: 227 GARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGE 286
           G RA+ R    RA P ST P                         +P +H   GG P G+
Sbjct: 455 GKRAKER--PPRARPASTSP-------------------------SPGAHGRRGG-PEGK 486

Query: 287 RSSREPLLDPS--KAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVR--TD 342
            SSR P   P    ++R+ +   +R A   P S            R P+  K   R    
Sbjct: 487 SSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHS----------PSRSPSPKKPLSRDKDG 536

Query: 343 LSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARP---GKPAPRGSAP 399
              A   +  + RA   ++      +  R   S       T +R RP    +P+P  S+ 
Sbjct: 537 EGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSS 596

Query: 400 PARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRP 444
                        +   G   GS  + S GT +  TR  SR P P
Sbjct: 597 CLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRS-RTRSPSRTPSP 640



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 83/339 (24%), Positives = 121/339 (35%), Gaps = 63/339 (18%)

Query: 206 WGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGV 265
           W  S   PPP+    + GG   +R + R   + +C  S+       +     R R   G 
Sbjct: 159 WSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGS 218

Query: 266 QRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRL 325
           +R+R     S S+   R    +  + P        R S   ++  +H+  PSL++     
Sbjct: 219 RRKR--RHRSRSSKCKRKEKNKEKKRP--HTESPGRRSHRHSSGSSHS--PSLSSHY--- 269

Query: 326 GGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGS---------- 375
               R P+ L    R +      +     R+  P+ GS  W   +R+GGS          
Sbjct: 270 -SDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSG-WGSPQRNGGSGQRSGAHGGR 327

Query: 376 --------------------SGARTLPTPSRARPGKPAPRGSAPPARLRGG--GGGSGLT 413
                                 A   PTP       P+PR SAP ++ RGG   GG+G  
Sbjct: 328 PGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPR-SAPSSQGRGGRAAGGAGRR 386

Query: 414 QLVGSGRGSGVTHSVGTHALATRRGSRAPRPV---GVLRGVPHFRPLSSP-----APQSP 465
           +     R      S  + +   RRG R PRP    G  R +   R  S       AP   
Sbjct: 387 R----RRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPG 442

Query: 466 PRSPSVRAFGPRLGAGRLSCPQAPRAAALPGIAVLAPSP 504
           P   S R  G   G G+ +  + PRA      A  +PSP
Sbjct: 443 PEPGSERGHG---GHGKRAKERPPRARP----ASTSPSP 474


>gi|113430175 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1934

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 137/494 (27%), Positives = 179/494 (36%), Gaps = 77/494 (15%)

Query: 87  AAVSGPSRQRRT-SRARTALWGRRS--RRAAGPGLDC-------AGSAPAPSGAQSCGGP 136
           A +SG SR RR  +   +AL G RS   RA  P   C       A  A AP+     GG 
Sbjct: 202 AMLSGRSRARRAIAPTPSALRGYRSWAHRAIAPTPGCLYSDRSRAHRAIAPARGTKHGGR 261

Query: 137 APASALRRPLTQWDASGGGGRGSHS---GPRAGTPGGGRSSRAGARRKTPLSLCPLKLRK 193
           + A    R +     S  G R   S    P  G   GGRS    A   TP SLC      
Sbjct: 262 SWAC---RSIAPKPGSLCGDRSQASRAIDPTLGARRGGRSRAHRAIAPTPGSLC-----G 313

Query: 194 GSSRRCQGLGSSWG-----GSGTP----PPPRALWNRHGGAAGARAQVRGSEK--RACPG 242
             SR C  +  + G      S  P    P P AL         A A   G+ +  R+   
Sbjct: 314 NRSRACGAIALTPGVLCGVRSRVPKDITPTPGALRGYKSWVCRAIAPTPGALRGDRSAAR 373

Query: 243 STLPPSSVLAGCVGTRARG-----HGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPS 297
           + +  +    G   +RAR       G +Q  R S   + + + G   G+RS+      P+
Sbjct: 374 TAIVRTPGALGRDRSRARSAIASTPGTLQGNRSSVSKAIAPAPGALRGDRSAARTAFVPT 433

Query: 298 KAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEE---EDPRSG 354
             A       AR A AS P               PT   GA+R   S A      +P + 
Sbjct: 434 PGALHRDRSRARSAIASTPGTLRGNTSSACKAIAPT--PGALRGYKSWARRAIAPNPGAW 491

Query: 355 RALEPAQGSELWARAERHGGS-SGART--LPTPSRARPGKPAPRG--SAPPARLRG--GG 407
           R      G+ +       GG+ S ART   PTP   R  +P  R   ++ PA LRG    
Sbjct: 492 RGYRSTTGTAIAPNLGALGGNRSAARTDIAPTPGALRGYRPRSRRAIASTPATLRGEKSR 551

Query: 408 GGSGLTQLVGSGRGSG-------VTHSVGTHALATRRG-SRAPRPVGVLRGVPHFRPLSS 459
             + L    G+ RG G       V  +     + +R G   AP    + R  P  R   +
Sbjct: 552 AHTSLAPAPGALRGDGSRARRAIVPTTCPLCEIWSRVGIGIAPIADALRRDRPPVRRAIA 611

Query: 460 PAPQS--PPRSPSVRAFGPRLGAGRLSCPQAPRA-AALPGI---------AVLAPSPAHD 507
           P P +    RS  + A  P  GA       A RA A  PG            +AP+P   
Sbjct: 612 PTPGALRCDRSRELTAIDPTPGALCSDRSGASRAIAPTPGTLCSERSRVRRAIAPTP--- 668

Query: 508 WGGQRCEGCGGGSQ 521
                C  CG GSQ
Sbjct: 669 -----CALCGKGSQ 677



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 62/227 (27%), Positives = 77/227 (33%), Gaps = 46/227 (20%)

Query: 327 GGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEP---AQGSELWARAERHGGSS------G 377
           GG RKP  L+    + LS    E P S    E     +G    +  +R   SS       
Sbjct: 104 GGGRKPHELESTTPSQLSQKVPEKPASSVPREDDWRCKGDLRRSLGKRENPSSPTVPSES 163

Query: 378 ARTL------------PTPSRARPG--KPAPRGSAPPARLRGGGGGSGLTQLVGSGRGSG 423
            R L            PTP  A PG    APR  AP       G       +  +     
Sbjct: 164 KRALRDDRSQEPTAIAPTPG-ALPGDRSGAPRAIAPTPGAMLSGRSRARRAIAPTPSALR 222

Query: 424 VTHSVGTHALATRRG------SRAPRPVGVLRGVPH------FRPLS-SPAPQSPPRSPS 470
              S    A+A   G      SRA R +   RG  H       R ++  P      RS +
Sbjct: 223 GYRSWAHRAIAPTPGCLYSDRSRAHRAIAPARGTKHGGRSWACRSIAPKPGSLCGDRSQA 282

Query: 471 VRAFGPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCG 517
            RA  P LGA R    +A RA        +AP+P     G R   CG
Sbjct: 283 SRAIDPTLGARRGGRSRAHRA--------IAPTPG-SLCGNRSRACG 320


>gi|239745974 PREDICTED: hypothetical protein XP_002343630 [Homo
           sapiens]
          Length = 538

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 115/430 (26%), Positives = 144/430 (33%), Gaps = 71/430 (16%)

Query: 162 GPR--AGTPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALW 219
           GP+  A  P   R+S A  R   P  +     R G      GLGS W       P RA+ 
Sbjct: 92  GPKSWAPAPRRQRASSAQVRAARPAGMAAGTGRSGPGSARLGLGSGW------DPARAVA 145

Query: 220 NRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVG--TRARGHGGVQRQRFSAPSSHS 277
            R   A GA    R     A  G   P   +  G       A G    +RQR   P+   
Sbjct: 146 PRAARALGAALFGRAVHTAALSG---PHCRLRCGARAFYAAAGGASSRRRQRGRNPALIV 202

Query: 278 TS-GGRPTGERSSREPLLDPSKAARASALPTARVAHASP------PSLAAAQWRLGGGKR 330
              G R  G  +S  P L P     AS  P   +    P      P+L   + R   GK 
Sbjct: 203 RGPGPRRGGGLTSAPPGLPP----LASPPPFWELPRPPPPPPPPGPALLPRRLRELRGKE 258

Query: 331 ---------------KPTVLKGAVRTDLSTAEEEDPRSG-----RALEPAQ-GSELWARA 369
                           P + +G+ R       E +  S        L P   G+ L A+ 
Sbjct: 259 VGLRPRTRGWTTCVVSPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQG 318

Query: 370 ER---------HGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGR 420
            R         +G   G     +P R  PG+PA   S  P     G    GL+     GR
Sbjct: 319 PRSSTPECPVVNGSEWGLAAPLSPERGSPGRPAFLRS--PGLCGPGPVPGGLSVPTPCGR 376

Query: 421 GSGVTHSV----------GTHALATRRGSRAPRPVGVLR-GVPHFRPLSSPA--PQSPPR 467
           G+G               G   +A RR  R       LR G P  +P +SPA  P   PR
Sbjct: 377 GAGDFSEADLADRAFPVRGAGPIAGRRRRRGWTFAAALRKGAPREQPPASPAASPCQAPR 436

Query: 468 SPSVRAFGPRL-GAGRLSCPQ-APRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAG 525
           +P      PRL G      P+  P A    G+ VL P PA   G       G    P   
Sbjct: 437 APEKETEAPRLRGRATAVAPRPLPAAPGFSGLCVLQPFPARSRGLGVPSQQGPTGSPGCR 496

Query: 526 RRAERGKRGA 535
            RA   + GA
Sbjct: 497 DRASAPRAGA 506


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 127/491 (25%), Positives = 158/491 (32%), Gaps = 67/491 (13%)

Query: 68   GPTRPSGSLTTRRP--RDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCAGSAP 125
            GP  P G L    P  R+ GE    G    R   +    L G    R    G++     P
Sbjct: 1700 GPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGP-KGDPGLPGAPGER----GIEGFRGPP 1754

Query: 126  APSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGP--------RAGTPGGGRSSRAG 177
             P G     GPA     R P      SG  G+   +GP        +AG P  GR    G
Sbjct: 1755 GPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDP--GRDGLPG 1812

Query: 178  ARRKTPL---SLCPLKLRKGSSRRCQGLGSSWGGSGTP-PPPRALWNRHGGAAGARAQVR 233
             R +  L   S  P    K       GL    G  G P    R       GA+G   +  
Sbjct: 1813 LRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDG 1872

Query: 234  GSEKRACPGSTLPPSSV-LAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREP 292
               +R  PG   P     L G VG   +G  GV              G  P G+R     
Sbjct: 1873 PKGERGAPGILGPQGPPGLPGPVGPPGQGFPGV------------PGGTGPKGDRGE--- 1917

Query: 293  LLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRT--DLSTAEEED 350
                + +     LP  R     P S+      L     K + L+  V T  + S +    
Sbjct: 1918 ----TGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPV 1973

Query: 351  PRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAP-------RGSAPPARL 403
            P   R  +   G +     E   G  G R L    R  PG   P       RG   P+ L
Sbjct: 1974 PERRRGPKGDSGEQGPPGKEGPIGFPGERGL-KGDRGDPGPQGPPGLALGERGPPGPSGL 2032

Query: 404  RGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQ 463
             G  G  G+  L G   G G     G       +G R  +      G+P      +P P 
Sbjct: 2033 AGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLP-----GTPGPP 2087

Query: 464  SPPRSPSVRAFGPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPF 523
             PP  P V    P  G   LS  Q P     PG+      P  + G Q  +G   G    
Sbjct: 2088 GPP-GPKVSVDEPGPG---LSGEQGP-----PGLKGAKGEPGSN-GDQGPKG-DRGVPGI 2136

Query: 524  AGRRAERGKRG 534
             G R E G RG
Sbjct: 2137 KGDRGEPGPRG 2147



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 113/423 (26%), Positives = 133/423 (31%), Gaps = 85/423 (20%)

Query: 116  PGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSR 175
            PGL      P P G     GP  A  L  P      SG  G    +GP    PG G +  
Sbjct: 2167 PGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGP----PGRGLTGP 2222

Query: 176  AGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGS 235
             GA                      GL    G SG   P         G+ G   QV  +
Sbjct: 2223 TGA---------------------VGLPGPPGPSGLVGPQ--------GSPGLPGQVGET 2253

Query: 236  EKRACPGSTLPPSSVLAGCVGTRA-RGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLL 294
             K   PG          G  G    RG  GV       P S    G  P G +    P  
Sbjct: 2254 GKPGAPGRD--------GASGKDGDRGSPGV-------PGSPGLPG--PVGPKGEPGPTG 2296

Query: 295  DPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSG 354
             P +A     LP A+    +P  LA       G K             L     E   +G
Sbjct: 2297 APGQA--VVGLPGAKGEKGAPGGLAGDLVGEPGAKGD---------RGLPGPRGEKGEAG 2345

Query: 355  RALEPAQGSELWARAERHGGSSGARTLP-TPSRARPGKPAPRGSAPPARLRGGGGGSGLT 413
            RA EP    E     +   G+ G +     P    PG P P G  PP    G  G  GL 
Sbjct: 2346 RAGEPGDPGE-----DGQKGAPGPKGFKGDPGVGVPGSPGPPG--PP----GVKGDLGLP 2394

Query: 414  QLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRA 473
             L G+    GV    G        G   P     L G P    +  P P  PP  P   +
Sbjct: 2395 GLPGA---PGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGI--PGPLGPPGPPG--S 2447

Query: 474  FGPRLGAGRLSCPQAPRAAALPGIAVLAPSPA--HDWGGQRCEGCGGGSQPFAGRRAERG 531
             GP  GA  L   +      LPG       P    + G    EG  G + P  G R ERG
Sbjct: 2448 VGPP-GASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGP-PGSRGERG 2505

Query: 532  KRG 534
            ++G
Sbjct: 2506 EKG 2508



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 56/193 (29%), Positives = 68/193 (35%), Gaps = 33/193 (17%)

Query: 360  AQGSELWARAERHGGSSGARTLP-TPS----RARPGKPAPRGSAPPARLRGGGGGSGLTQ 414
            A+G   +  A+   GS G    P TP     +  PG P PRG       RG  G  G   
Sbjct: 1294 AKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPG 1353

Query: 415  LVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAF 474
             V  G G G         L  R+G   P      RG     PL  P P+ PP  P     
Sbjct: 1354 QVIGGEGPG---------LPGRKGDPGPSGPPGPRG-----PLGDPGPRGPPGLPGTAMK 1399

Query: 475  GPRLGAGRLSCPQ------APRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFA---- 524
            G +   G    P       AP    LPG+   +P P    G    +G  G S+  A    
Sbjct: 1400 GDKGDRGERGPPGPGEGGIAPGEPGLPGLPG-SPGPQGPVGPPGKKGEKGDSEDGAPGLP 1458

Query: 525  ---GRRAERGKRG 534
               G   E+G RG
Sbjct: 1459 GQPGSPGEQGPRG 1471



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 121/490 (24%), Positives = 156/490 (31%), Gaps = 79/490 (16%)

Query: 62   PAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCA 121
            P GL  GP  P G      P   G     G +     S+    L G R  R         
Sbjct: 1888 PPGLP-GPVGPPGQGFPGVPGGTGPKGDRGETG----SKGEQGLPGERGLRGE------P 1936

Query: 122  GSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARRK 181
            GS P         G   ASALR  +  WD S G         R   P G    +    ++
Sbjct: 1937 GSVPNVDRLLETAG-IKASALREIVETWDESSGSFLPVPERRRG--PKGDSGEQGPPGKE 1993

Query: 182  TPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACP 241
             P+         G     +GL    G  G   PP       G A G R     S     P
Sbjct: 1994 GPIGF------PGE----RGLKGDRGDPGPQGPP-------GLALGERGPPGPSGLAGEP 2036

Query: 242  GSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAAR 301
            G    P   L G    RA G G                 GRP GER  R    +  +  R
Sbjct: 2037 GKPGIPG--LPG----RAGGVG---------------EAGRP-GERGERGEKGERGEQGR 2074

Query: 302  AS--ALPTARVAHASP-PSLAAAQWRLG-GGKRKPTVLKGAVRTDLSTAEEEDPRSGRAL 357
                 LP        P P ++  +   G  G++ P  LKGA + +  +  ++ P+  R +
Sbjct: 2075 DGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGA-KGEPGSNGDQGPKGDRGV 2133

Query: 358  EPAQGS--ELWARAER-HGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQ 414
               +G   E   R +  + G  G R +  P   +PG   PRG   P    G  G  G   
Sbjct: 2134 PGIKGDRGEPGPRGQDGNPGLPGERGMAGPE-GKPGLQGPRGPPGPVGGHGDPGPPGAPG 2192

Query: 415  LVGSGRGSGVTHSVGTHALATRRGSRAPRPVGV--LRGVPHFRPLSSPAPQSPPRSPSVR 472
            L G     G +   G        G     P G   L G P   P     PQ  P  P   
Sbjct: 2193 LAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPP--GPSGLVGPQGSPGLPGQV 2250

Query: 473  AFGPRLGA-------GRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAG 525
                + GA       G+     +P     PG+    P P    G     G  G  Q   G
Sbjct: 2251 GETGKPGAPGRDGASGKDGDRGSPGVPGSPGL----PGPVGPKGEPGPTGAPG--QAVVG 2304

Query: 526  RRAERGKRGA 535
                +G++GA
Sbjct: 2305 LPGAKGEKGA 2314



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 116/474 (24%), Positives = 135/474 (28%), Gaps = 91/474 (19%)

Query: 115  GPGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSS 174
            GPGL      P PSG     GP      R P      +  G +G       G PG G   
Sbjct: 1360 GPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRG--ERGPPGPGEGG 1417

Query: 175  RAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRG 234
             A      P                 GL  S G  G   PP     +     GA      
Sbjct: 1418 IAPGEPGLP-----------------GLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQ 1460

Query: 235  SEKRACPGSTLPPSSVLAGCVGTRA----RGHGGVQRQRFSAPSSHSTSGGRP--TGERS 288
                   G   PP ++  G  G R      G  G + +R   P   + S G P   G   
Sbjct: 1461 PGSPGEQGPRGPPGAI--GPKGDRGFPGPLGEAGEKGER--GPPGPAGSRGLPGVAGRPG 1516

Query: 289  SREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAV-----RTDL 343
            ++ P   P         PT R      P        +G     P   KG V     R   
Sbjct: 1517 AKGPEGPPG--------PTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGAT 1568

Query: 344  STAEEEDPRSGRALEPAQGSE----------LWARAERHGGSSGARTLPTPSRARPGKPA 393
                E  P  G  L    G +          L  RA   G S      P   +  PG+P 
Sbjct: 1569 GVQGERGP-PGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSG-----PPGEKGDPGRPG 1622

Query: 394  PRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVP- 452
            P G   P   RG  G  G     G     G+    G   L    G R P      +G P 
Sbjct: 1623 PPGPVGP---RGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPG 1679

Query: 453  ----HFRPLSS--------PAPQSPP-----RSPSVR---------AFGPRLGAGRLSCP 486
                +  P SS        P P  PP       P  R           GPR   G    P
Sbjct: 1680 EDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLP 1739

Query: 487  QAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQP--FAGRRAERGKRGAGVP 538
             AP    + G     P P  D G +   G  G   P    GR    GK GA  P
Sbjct: 1740 GAPGERGIEGFRG-PPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGP 1792



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 88/364 (24%), Positives = 117/364 (32%), Gaps = 58/364 (15%)

Query: 125  PAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRA--GTPGGGRSSRAGARRKT 182
            P PSG +   GP     +  PL      G  G    SG +   G PG G     G R + 
Sbjct: 2418 PGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEP 2477

Query: 183  PLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPG 242
             +            R   G     G  G   PP +      G  G +  V  +  +   G
Sbjct: 2478 GI------------RGEDGRPGQEGPRGLTGPPGSR-----GERGEKGDVGSAGLKGDKG 2520

Query: 243  STLPPSSVLAGCVGTR-ARGHGGVQRQR-FSAPSSHSTSGGRPTGERSSREP-------- 292
                 S+V+ G  G R A+G  G +  R            G P  + S  EP        
Sbjct: 2521 D----SAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGL 2576

Query: 293  -----LLDPSKAARASALP--TARVAHASPPSLAAAQWRLG----GGKRKPTVLKGAVRT 341
                 LL P     A+ +P           P +   +  +G     G +    +KGA   
Sbjct: 2577 PGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGL 2636

Query: 342  DLSTAE--EEDPRSGRALEPAQGSELWARAERHGGSSGARTL--PTPSRARPGKPAPRGS 397
            D    +  E  P     L   +G           G+ G   L  P   R   G+P P+G 
Sbjct: 2637 DGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGD 2696

Query: 398  APPARLRGG---GGGSGLTQLVGSGRGSGVTHSV---GTHALATRRGSRAP---RPVGVL 448
                  RG    GG  G +   GS    G   SV   G   L  ++G R P   R VG  
Sbjct: 2697 QGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGA- 2755

Query: 449  RGVP 452
             GVP
Sbjct: 2756 PGVP 2759


>gi|122692281 hypothetical protein LOC645369 [Homo sapiens]
          Length = 621

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 81/296 (27%), Positives = 106/296 (35%), Gaps = 62/296 (20%)

Query: 69  PTRPSGSLTTRRPRDAGEAA--VSGPSRQRRTSRARTALWGRRSRRAAGPGLDCAGSAPA 126
           P  PSG     RPR A       S P   R       A++     R+   G   A +A A
Sbjct: 288 PAAPSGG----RPRGAASPPDLASSPRCPREPPSLAEAVYSVYRERSGVAGSRRAAAATA 343

Query: 127 PSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARRKTPLS- 185
            + A SC  PAP S    P   W                     GR S A +   + LS 
Sbjct: 344 AAAASSCSSPAPCS----PPESW---------------------GRQSTASSFVDSSLSA 378

Query: 186 --LCPLKLRKGSSRRCQGLGSSW----GGSGTPPPPRALWNRHGGAAGARAQVRGSEKRA 239
             L PL+  +      +G   SW    G  G+   PR      G    +   +RG+E  +
Sbjct: 379 FALLPLQGGRDRGGDAEGASCSWQRPPGERGSQEIPR------GELDLSMTNLRGAE-GS 431

Query: 240 CPGSTLPPSSVLAGCVGTRARGHGG--VQRQRFSAPSSHSTSGGRPTGERSSREPLLDPS 297
             G+   P           ARG GG   +  R++A    STSG        S EP   P 
Sbjct: 432 MRGARREPEEPEGAVAARAARGQGGRLPRTGRYAALRRRSTSGLPDYRAPPSPEPPPSPG 491

Query: 298 KAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRS 353
            A   S+ P A+ A  SPP       RL G    PT      R D  +++ +DP S
Sbjct: 492 SADPDSS-PLAKAASPSPP------LRLEGS--PPT------RRDSGSSQSDDPSS 532



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 29/72 (40%), Positives = 33/72 (45%), Gaps = 5/72 (6%)

Query: 115 GPGLDCAGSAPAPSGAQSCGG---PAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGG 171
           G  +   G  P  +G    GG   P   S+ R P T   +S G    S S PRA  PGG 
Sbjct: 66  GIAMAVVGYWPKATGTNREGGKQLPPAGSSHRVPTTANSSSSGSKNRSRSHPRA--PGGV 123

Query: 172 RSSRAGARRKTP 183
            SS AGA R TP
Sbjct: 124 NSSSAGAPRSTP 135



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 88/384 (22%), Positives = 118/384 (30%), Gaps = 58/384 (15%)

Query: 121 AGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARR 180
           A +A A S + S    AP  A+  PL  +  S    RG    P      GG     GA  
Sbjct: 224 AAAAAAASSSSSAPAAAPPGAI--PLNGF-LSYVQSRGLELKPGGC---GGSGDAFGAAA 277

Query: 181 KTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPR----------ALWNRHGGAAGARA 230
                  P      S  R +G  S    + +P  PR          +++    G AG+R 
Sbjct: 278 MLAKGSWPPHPAAPSGGRPRGAASPPDLASSPRCPREPPSLAEAVYSVYRERSGVAGSRR 337

Query: 231 QVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQ--------------RQRFSAPSSH 276
               +   A    + P         G ++     V               R R       
Sbjct: 338 AAAATAAAAASSCSSPAPCSPPESWGRQSTASSFVDSSLSAFALLPLQGGRDRGGDAEGA 397

Query: 277 STSGGRPTGERSSRE------PLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKR 330
           S S  RP GER S+E       L   +      ++  AR     P    AA+   G G R
Sbjct: 398 SCSWQRPPGERGSQEIPRGELDLSMTNLRGAEGSMRGARREPEEPEGAVAARAARGQGGR 457

Query: 331 KPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPG 390
            P   + A     ST+   D R+  + EP              GS+   + P    A P 
Sbjct: 458 LPRTGRYAALRRRSTSGLPDYRAPPSPEPPPSP----------GSADPDSSPLAKAASPS 507

Query: 391 KPAPRGSAPPARLRGGGGGS--------GLTQLVGSGRGSGVTHSVGTHALATRRGSRAP 442
            P     +PP R   G   S        G T L  +G     T SV        R S   
Sbjct: 508 PPLRLEGSPPTRRDSGSSQSDDPSSSNKGYTPLREAGTS---TESVLDAVAGQTRDSAVA 564

Query: 443 RPV-GVLRGVPHFRPLSSPAPQSP 465
            PV G  +  P       P  + P
Sbjct: 565 APVLGAEQSSPEGASQEPPTAEQP 588


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 127/513 (24%), Positives = 159/513 (30%), Gaps = 104/513 (20%)

Query: 41  IARNDCWDRVPRGSVTDSNHTPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSR 100
           + +    DR PRG            + GP  P G       RD GE   +GP        
Sbjct: 30  VRKGPAGDRGPRG------------ERGPPGPPG-------RD-GEDGPTGPPGPPGPP- 68

Query: 101 ARTALWGRRSRRAAGPGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSH 160
               L G  + +  G G+   G  P P G     GP  A+    P      +G  G    
Sbjct: 69  GPPGLGGNFAAQYDGKGV---GLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQ 125

Query: 161 SGPRAGTPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWN 220
           +GP       G   +AG          P K  +   R   G   + G  GTP  P     
Sbjct: 126 TGPAGARGPAGPPGKAGEDGH------PGKPGRPGERGVVGPQGARGFPGTPGLPGFKGI 179

Query: 221 R-HGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTS 279
           R H G  G + Q      +  PG+  P  +   G  G  ARG  G +R R  AP      
Sbjct: 180 RGHNGLDGLKGQPGAPGVKGEPGA--PGENGTPGQTG--ARGLPG-ERGRVGAPG----- 229

Query: 280 GGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLG-------GGKRKP 332
              P G R         S  +     P   +  A PP    A    G        G   P
Sbjct: 230 ---PAGARG--------SDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGP 278

Query: 333 TVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKP 392
              +G V             SG    P         A    G+ GA  LP  + A PG P
Sbjct: 279 AGPRGEVGL--------PGLSGPVGPPGNPG-----ANGLTGAKGAAGLPGVAGA-PGLP 324

Query: 393 APRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVP 452
            PRG   P    G  G  GL    G     G + + G    A  +G   P      RG  
Sbjct: 325 GPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRG-- 382

Query: 453 HFRPLSSPAPQSPPRSPSVRAFGPRLGAGRLSCPQAPRAAALPG----IAVLAPSPAHDW 508
              P        PP  P +R               +P +  LPG      V+ P      
Sbjct: 383 ---PNGEAGSAGPPGPPGLRG--------------SPGSRGLPGADGRAGVMGPP----- 420

Query: 509 GGQRCEGCGG--GSQPFAGRRAERGKRG-AGVP 538
           G +   G  G  G    AGR  E G  G  G+P
Sbjct: 421 GSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLP 453



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 125/495 (25%), Positives = 161/495 (32%), Gaps = 77/495 (15%)

Query: 66  DCGPTRPSGSLTTRRPR-DAGEAAVSGPSRQRRTSRARTALWGRRSRR-----AAGPGLD 119
           + GP  P+G      PR + G   +SGP        A   L G +        A  PGL 
Sbjct: 272 NAGPAGPAG------PRGEVGLPGLSGPVGPPGNPGAN-GLTGAKGAAGLPGVAGAPGLP 324

Query: 120 CAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPG-GGRSSRAGA 178
                P P GA    G         P      SG  G    +GP+ G PG  G   + G 
Sbjct: 325 GPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQ-GPPGPSGEEGKRGP 383

Query: 179 RRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKR 238
             +   +  P       S   +GL  + G +G   PP +      G AG R     + + 
Sbjct: 384 NGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGS--RGASGPAGVRGPNGDAGRP 441

Query: 239 ACPG----STLPPSSVLAGCVGTRAR-GHGGVQRQRFSAPSSHSTSGGRP--TGERSSRE 291
             PG      LP S    G  G     G  G+  +    P   + + G P   G    + 
Sbjct: 442 GEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGR--PGPIGPAGARGEPGNIGFPGPKG 499

Query: 292 PLLDPSK----------AARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRT 341
           P  DP K           AR +  P        PP     Q   G G++ P    G    
Sbjct: 500 PTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQG--GKGEQGPPGPPGF--- 554

Query: 342 DLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPS--RARPGKPAPRGSAP 399
                       G         E+    ER  G  G   LP P+  R   G P   G+A 
Sbjct: 555 -----------QGLPGPSGPAGEVGKPGER--GLHGEFGLPGPAGPRGERGPPGESGAAG 601

Query: 400 PARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSS 459
           P    G  G SG     G+    GV  +VGT       G   P  +   RG         
Sbjct: 602 PTGPIGSRGPSGPPGPDGNKGEPGVVGAVGT------AGPSGPSGLPGERGA-----AGI 650

Query: 460 PAPQSPPRSPSVRAFGPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGG 519
           P  +     P +R        G +  P    A   PG AV AP PA   G +   G  G 
Sbjct: 651 PGGKGEKGEPGLR--------GEIGNPGRDGARGAPG-AVGAPGPAGATGDRGEAGAAGP 701

Query: 520 SQPFAGRRAERGKRG 534
           + P AG R   G+RG
Sbjct: 702 AGP-AGPRGSPGERG 715



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 126/459 (27%), Positives = 162/459 (35%), Gaps = 85/459 (18%)

Query: 117 GLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPG----GGR 172
           GL  A  AP P G     GP     ++           GG+G    P  G PG     G 
Sbjct: 514 GLAGARGAPGPDGNNGAQGPPGPQGVQ-----------GGKGEQGPP--GPPGFQGLPGP 560

Query: 173 SSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHG--GAAGARA 230
           S  AG            ++ K   R   GL   +G  G P  PR      G  GAAG   
Sbjct: 561 SGPAG------------EVGKPGER---GLHGEFGLPG-PAGPRGERGPPGESGAAGPTG 604

Query: 231 QV--RGSEKRACPGSTLPPSSVLAGCVGTRA-RGHGGVQRQRFSAPSSHSTSGGRPTGER 287
            +  RG      P        V+ G VGT    G  G+  +R +A        G P G+ 
Sbjct: 605 PIGSRGPSGPPGPDGNKGEPGVV-GAVGTAGPSGPSGLPGERGAA--------GIPGGKG 655

Query: 288 SSREPLL--DPSKAARASALPTARVAHASPPSLAAAQWRLGG--GKRKPTVLKGAV--RT 341
              EP L  +     R  A        A  P+ A       G  G   P   +G+   R 
Sbjct: 656 EKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERG 715

Query: 342 DLSTAEEED--PRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAP 399
           ++  A        +G A +P    E  A+  +  G +G    PT      G   P G   
Sbjct: 716 EVGPAGPNGFAGPAGAAGQPGAKGERGAKGPK--GENGV-VGPTGPVGAAGPAGPNGPPG 772

Query: 400 PARLRGGGGGSGLTQLVG-SGR-----GSGVTHSVGTHALATRRGSRAPR----PVGVLR 449
           PA  RG GG  G+T   G +GR      SG++   G    A + G R PR    PVG   
Sbjct: 773 PAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTG 832

Query: 450 -----GVPHFRPLSSPAPQS----PPRSPSVRAFGPRLGA-GRLSCPQAPRAAALPGI-- 497
                G P F     P+ ++    PP +P  +     LGA G L  P +     LPG+  
Sbjct: 833 EVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGL---LGAPGILGLPGSRGERGLPGVAG 889

Query: 498 AVLAPSPAHDWGGQRCEGCGG--GSQPFAGRRAERGKRG 534
           AV  P P    G     G  G  GS    G   E G+ G
Sbjct: 890 AVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDG 928



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 123/488 (25%), Positives = 156/488 (31%), Gaps = 80/488 (16%)

Query: 68   GPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALW--GRRSRRAAGPGLDCAGSAP 125
            GP+ PSG      P + G A + G   ++     R  +   GR   R A PG   A  AP
Sbjct: 634  GPSGPSGL-----PGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGA-PG---AVGAP 684

Query: 126  APSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARRKTPLS 185
             P+GA    G A A+    P     + G  G    +GP       G + + GA+ +    
Sbjct: 685  GPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGER--- 741

Query: 186  LCPLKLRKGSSRRCQGLG--SSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGS 243
                K  KG +      G   + G +G   PP    +R  G         G+  R  P  
Sbjct: 742  --GAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGP-- 797

Query: 244  TLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARAS 303
              P  S ++G  G      G   ++    P       GR TGE  +  P   P  A    
Sbjct: 798  --PGPSGISGPPGP----PGPAGKEGLRGPRGDQGPVGR-TGEVGAVGP---PGFAGEKG 847

Query: 304  ALPTARVAHASPPSLAAAQWRLGG----------GKRKPTVLKGAVRTDLSTAEEEDPRS 353
              P+     A PP     Q  LG           G+R    + GAV  +        P  
Sbjct: 848  --PSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAV-GEPGPLGIAGPPG 904

Query: 354  GRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLT 413
             R    A GS     A    G  G           PG   P G       +G  G  G  
Sbjct: 905  ARGPPGAVGSPGVNGAPGEAGRDG----------NPGNDGPPGRDGQPGHKGERGYPGNI 954

Query: 414  QLVGSGRGSGVTHSVGTHALATRRGSRAPR-PVGVLRGVPHFRPLSSPAPQSPPRSPSVR 472
              VG+    G    VG       RG   P  PVG             PA    PR PS  
Sbjct: 955  GPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVG-------------PAGAVGPRGPS-- 999

Query: 473  AFGPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGG--GSQPFAGRRAER 530
              GP+   G    P       LPG+        H+ G Q   G  G  G Q   G     
Sbjct: 1000 --GPQGIRGDKGEPGEKGPRGLPGL------KGHN-GLQGLPGIAGHHGDQGAPGSVGPA 1050

Query: 531  GKRGAGVP 538
            G RG   P
Sbjct: 1051 GPRGPAGP 1058



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 119/479 (24%), Positives = 152/479 (31%), Gaps = 103/479 (21%)

Query: 51   PRGSVTDSNHTPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRS 110
            P G+  D     A    GP  P GS     P + GE   +GP+     + A      +  
Sbjct: 686  PAGATGDRGEAGAAGPAGPAGPRGS-----PGERGEVGPAGPNGFAGPAGAAGQPGAKGE 740

Query: 111  RRAAGPG-----------LDCAGSA-----PAPSGAQSCGGPA-----PASALRR-PLTQ 148
            R A GP            +  AG A     P P+G++  GGP      P +A R  P   
Sbjct: 741  RGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGP 800

Query: 149  WDASGG------GGRGSHSGPRAGTPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGL 202
               SG        G+    GPR      GR+   GA      +       KG S    G 
Sbjct: 801  SGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAG-----EKGPS----GE 851

Query: 203  GSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGST----LPPSSVLAGCVGTR 258
              + G  GTP P   L     GA G         +R  PG       P    +AG  G R
Sbjct: 852  AGTAGPPGTPGPQGLL-----GAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGAR 906

Query: 259  ----ARGHGGV-----QRQRFSAPSSHSTSG--GRPTGERSSREP-LLDPSKAARASAL- 305
                A G  GV     +  R   P +    G  G+P  +     P  + P  AA A    
Sbjct: 907  GPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPH 966

Query: 306  ----PTARVAHASPPSLAAAQWRLGG-GKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPA 360
                P  +  +      +      G  G R P+  +G +R D     E+ PR    L+  
Sbjct: 967  GPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQG-IRGDKGEPGEKGPRGLPGLKGH 1025

Query: 361  QGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGR 420
             G +       H G  GA          PG   P G   PA   G  G  G T       
Sbjct: 1026 NGLQGLPGIAGHHGDQGA----------PGSVGPAGPRGPAGPSGPAGKDGRT------- 1068

Query: 421  GSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLG 479
              G   +VG              P G+     H  P   P P  PP  P V   G   G
Sbjct: 1069 --GHPGTVG--------------PAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFG 1111


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 83/335 (24%), Positives = 114/335 (34%), Gaps = 58/335 (17%)

Query: 109 RSRRAAGPGLDCAGSAPAPSGAQSCGGPAPASALR----------RPLTQWDASGGGGRG 158
           R+  A  PGL      P P G+     P   +ALR          +PL +     GG   
Sbjct: 15  RTPAARAPGL----LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70

Query: 159 SHSGPRAG---------------TPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLG 203
             S PRAG                P  GR  RA   + T         R   + R   LG
Sbjct: 71  PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130

Query: 204 SSW----------GGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAG 253
                         G  T  P R+       +AGAR    G      PG+  P  +  + 
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSAL-----SAGARRDTSG----PTPGTPSPAMARRSR 181

Query: 254 CVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVAHA 313
             GT      G+ R   SA     T G R +   +S     +PS AAR        +   
Sbjct: 182 AAGTEV----GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237

Query: 314 SPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHG 373
           +  SL+++   L    R     +G  R     ++ + P+  +AL P Q +     A    
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK-PKGLQALRPPQVTPPRKDAAPAL 296

Query: 374 GSSGARTLPTPS----RARPGKPAPRGSAP-PARL 403
           G   +  L TPS    +ARP  P    + P PA L
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATL 331



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 119/515 (23%), Positives = 171/515 (33%), Gaps = 99/515 (19%)

Query: 63  AGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCAG 122
           AG + G  RP+ S   R P +    +VS  S    T  +  A    R R +AG GL    
Sbjct: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA----RRRPSAGGGLQRPA 238

Query: 123 S-----------APAPSGAQSCGGP-APA----------SALRRPLT---QWDASGGGGR 157
           S           +PA SG  + G P APA           ALR P     + DA+   G 
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298

Query: 158 GSHSGPRAGTPGGGRSSRA----GARRKTPLSL-------CPLKLRKGSSRRCQGLGSSW 206
            S S     +P G ++        A    P +L        PL L   S      L +  
Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLP 358

Query: 207 GGSGTPP---PPRALWNRHGGAAGARA--QVRGSEKRACPGSTLPPSSV-LAGCVGTRAR 260
               TPP   PP             +    ++       P    PPS + L+    T + 
Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418

Query: 261 GHGGVQ----------RQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARV 310
           G   +Q          RQ  ++ +S S     P      + PL  P+     ++L  A  
Sbjct: 419 GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478

Query: 311 AHASPPSLAAAQWRLGGGKRKPTV-LKGAVRTDLSTAEE------EDPRSGRALEPAQGS 363
             +SP ++   Q         P   L   +   L T         + P +     P +  
Sbjct: 479 PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL 538

Query: 364 ELWARAERHGGSSGARTLPTPSRARPGKPAPRG-SAPPARLRGGGGGSGLTQLVGSGRGS 422
              A       S+    L TP    P  PAP    APP+ L                   
Sbjct: 539 PSLAPPPLQTASA---PLTTPHLETPPCPAPCPLQAPPSPL------------------- 576

Query: 423 GVTHSVGTHALATRRGSRAPRPVGV--LRGVPH--FRPLSSPAPQSPP-------RSPSV 471
             T    T +       +AP  +    L+G+P     PL++P PQ+PP       ++P  
Sbjct: 577 -TTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635

Query: 472 RAFGPRLGAGRLSCPQAPRAAALPGI-AVLAPSPA 505
               P L       PQAP A A+  + A  +P P+
Sbjct: 636 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 670



 Score = 32.7 bits (73), Expect = 0.91
 Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 7/98 (7%)

Query: 436 RRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAGRLSCPQAPRAAALP 495
           + G+ A  P     G+   RP  SP P  P    ++R  G     GR   P A RA  + 
Sbjct: 9   KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK--PLAERAGGIG 66

Query: 496 GIAVLAPSPAHDWGGQRCEGCGG---GSQPFAGRRAER 530
           G  +  P  A   G  R  G       S+P A  R ER
Sbjct: 67  GATI--PESAPRAGPTRSAGTSSRNPASRPPASGRGER 102



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 92/362 (25%), Positives = 123/362 (33%), Gaps = 58/362 (16%)

Query: 48  DRVPRGSVTDSNHTPAGLDCGPTRPSGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWG 107
           + V RG  T++          P R + S   RR           P+  RR+  A T +  
Sbjct: 140 ETVARGKATEA----------PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189

Query: 108 RRSRRAAGPGLDCAGSAPAPSGA--QSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRA 165
            R   +A P     G   + S A   S   P+PA A RRP      S GGG         
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA-ARRRP------SAGGGLQR------ 236

Query: 166 GTPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPR--ALWNRHG 223
                  +SR+ +   TPLS      R G S R           GTP  P   +     G
Sbjct: 237 ------PASRSLSSSATPLS---SPARSGPSAR-----------GTPRAPAHPSQPKPKG 276

Query: 224 GAAGARAQVRGSEKRACPGSTLPPSSVLA--GCVGTRARGHGGVQRQRFSAPSSHSTSGG 281
             A    QV    K A P      SS LA     GT+AR            P++      
Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLP---- 332

Query: 282 RPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKP---TVLKGA 338
            P+   ++  PL  PS +A  S L T     A+PPS A         +  P   T+    
Sbjct: 333 -PSPPLATPLPLAPPSPSAPPS-LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ 390

Query: 339 VRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSA 398
           V   L++   + P S  AL   Q +            S     P  ++A    P+   S 
Sbjct: 391 VPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAST 450

Query: 399 PP 400
           PP
Sbjct: 451 PP 452



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 66/262 (25%), Positives = 80/262 (30%), Gaps = 46/262 (17%)

Query: 111  RRAAGPGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGG 170
            RR   PG D + S P  + A + G P P S  R P +      G     HS     TP  
Sbjct: 856  RRPPTPGPDTSVSGPRLTLALAPGPPPPPS--RSPSS---TLSGPDLAGHSSSATSTPEE 910

Query: 171  GRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARA 230
             R   +G                             GG+   PPP A       AA +R 
Sbjct: 911  LRGYDSGPE---------------------------GGAAASPPPDAELAACHPAAWSRG 943

Query: 231  QVRGSEKRACPGSTLP------PSSVLAGCVGTRARGHGGVQRQ--RFSAPSSHSTSGGR 282
                   R  PG+ LP      P S    C      G               S  TSGG+
Sbjct: 944  PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGK 1003

Query: 283  PT----GERSSREPLLDPSKAARASALPTARVAHASPPS--LAAAQWRLGGGKRKPTVLK 336
                     SSR P           AL  + V H    +  LAAA+   GG    P   +
Sbjct: 1004 AAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAE 1063

Query: 337  GAVRTDLSTAEEEDPRSGRALE 358
            G   T  + A   D   GR  E
Sbjct: 1064 GGGVTGGARAALSDAELGRWAE 1085



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 47/174 (27%), Positives = 58/174 (33%), Gaps = 37/174 (21%)

Query: 389 PGKPAPRGSAPPARLRGGG--------------GGSGLTQLVGSGRGSGVTHSVGTHAL- 433
           PG P P     PA LR  G              GG G   +  S   +G T S GT +  
Sbjct: 30  PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89

Query: 434 ------ATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAGRLSCPQ 487
                 A+ RG RAP       G     P+SSP   S    P     GP    G+     
Sbjct: 90  PASRPPASGRGERAPPAKNTSPG-----PVSSPGRASGTTRP-----GP---LGQKGLRI 136

Query: 488 APRAAALPGIAVLAPSPAHDWGGQRCEGCG---GGSQPFAGRRAERGKRGAGVP 538
           +       G A  AP  +    G R +  G   G   P   RR+       G+P
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 190


>gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 426

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 106/403 (26%), Positives = 136/403 (33%), Gaps = 80/403 (19%)

Query: 112 RAAGPGLDCAGSAPAPSGAQSCGGPAPAS-----------ALRRPLT---QWDASGGGGR 157
           R   PG  C   AP P G  +  GPA  S           A +RP T   +W+ +     
Sbjct: 12  RTPAPG--CPEVAPQPEGTDA-PGPAVCSPTARAPPPILPAPQRPPTRAREWEGAAWA-- 66

Query: 158 GSHSGPRAGTPGGGRSSRA--GARRKTPLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPP 215
                  AG  G G +  A  G+RR   L   PL  R+ S     G   + G  G  P P
Sbjct: 67  -------AGATGVGAALLALPGSRR---LGRVPLTFREASPGPAPGAPRARGSCGREPGP 116

Query: 216 RALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSS 275
           R    R   +AG R     +  RA P      +  L   VG+  R   G      S P  
Sbjct: 117 RR--RRAPSSAGKRP---AAAARAAPPRQRSLARCLPRSVGSCVRPSVGP-----SLPRR 166

Query: 276 HSTSGGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVL 335
           H     R       R PL  P            R+  ASPP LAA           P   
Sbjct: 167 HCRRHCRC---HCRRRPLPKPPPLQ-------PRLGSASPPRLAAPLAGSRAPSLSPFPR 216

Query: 336 KGAVRTDLSTAEEEDP------RSGRALEPAQ---GSELWARAERHGGSSGARTLPTPSR 386
           +   R + S A    P      R G  +   +   G E   R  R G + G+  +P    
Sbjct: 217 RCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPA-GP 275

Query: 387 ARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVG 446
           A PG+   R +A   R RGGG G    +     +G GV   V   A  +    R P P  
Sbjct: 276 AAPGRAGERRAARQWRKRGGGPGVSPRE---GAQGEGVRGGVTPRARGSSTCLR-PSPAT 331

Query: 447 VLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAGRLSCPQAP 489
              G P+                ++ A GPRL A      + P
Sbjct: 332 WQGGAPY---------------RAIFAAGPRLSAPSAEAEEVP 359



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 92/357 (25%), Positives = 118/357 (33%), Gaps = 63/357 (17%)

Query: 67  CGPTRPSGSLTTRRPRDAGE----AAVSGPSRQRRTSRARTALWGRRSRRAAGPGLDCAG 122
           CG  R  G    R P  AG+    AA + P RQR  +R      G   R + GP L    
Sbjct: 110 CG--REPGPRRRRAPSSAGKRPAAAARAAPPRQRSLARCLPRSVGSCVRPSVGPSLP--- 164

Query: 123 SAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAGTPGGGRSSRAGARRKT 182
                   + C         RRPL +         GS S PR   P  G        R  
Sbjct: 165 -------RRHCRRHCRCHCRRRPLPK-PPPLQPRLGSASPPRLAAPLAG-------SRAP 209

Query: 183 PLSLCPLKLRKGSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGARAQVRGSEKR---- 238
            LS  P + R+ + R   G G         P PR+L +R G   GAR +  G E+R    
Sbjct: 210 SLSPFPRRCRRRAERSPAGHGL--------PLPRSL-SRGGEVVGARRRRGGEERRVRGR 260

Query: 239 ----ACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSSREP-- 292
               A     +P      G  G R        R+R   P      G +  G R    P  
Sbjct: 261 RQGCALGSPPIPAGPAAPGRAGERRAAR--QWRKRGGGPGVSPREGAQGEGVRGGVTPRA 318

Query: 293 -----LLDPSKAARASALPTARVAHASP----PSLAAAQWRLGGGKRKPTVLKGAVRTDL 343
                 L PS A      P   +  A P    PS  A +   G     PT         L
Sbjct: 319 RGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVPGGHTASNPTY------EPL 372

Query: 344 STAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPP 400
           S+   + P  GR   P+  +      +R  G     + P+ S      P+P  S PP
Sbjct: 373 SSRRTKAPSEGRD-SPSSPATSTHYLDRESGLGSVNSHPSRSPYNWSPPSP--SVPP 426


>gi|239749538 PREDICTED: hypothetical protein XP_002347080 [Homo
           sapiens]
          Length = 400

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 82/278 (29%), Positives = 99/278 (35%), Gaps = 38/278 (13%)

Query: 286 ERSSREPLLDPSKAAR----ASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRT 341
           ERSSR   L  +KA      AS  P  R A   P     +    G   R        +R 
Sbjct: 61  ERSSRH--LPQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAAR-------TLRR 111

Query: 342 DLSTAEEEDPR-SGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAP- 399
                + + PR +G A     G E W +        G  T P PS  R   P PR   P 
Sbjct: 112 GSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPA 171

Query: 400 PARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLS- 458
           PA  +G GGG     L     G G       +  A   G  A        G+   RPL  
Sbjct: 172 PAGGKGEGGGKESAVLWKGAEGGG--EKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLEL 229

Query: 459 --SPAPQSPPRSPSVRAF----GPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQR 512
              PA  S P SP +R F      R+GA  L+  QA   AA  G+    P+P        
Sbjct: 230 VPRPALPSAP-SPRIRCFLAPGRSRVGAA-LTEEQAAGEAAARGLWRRKPAPCPRGA--- 284

Query: 513 CEGCGGGSQPFAGRRAE---RGKRG------AGVPWRT 541
           C    GG      RRAE    G RG      +G  WR+
Sbjct: 285 CAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRS 322



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 93/372 (25%), Positives = 125/372 (33%), Gaps = 77/372 (20%)

Query: 20  LPSLGEKAL----TALSHQNP---EFPQIARNDCWDR-VPRGSVTDSNHT----PAGLDC 67
           +PSLG        T LS   P    FP    ++   R +P+    + +HT    PAG   
Sbjct: 29  IPSLGRNLHVSPGTVLSDLQPLGITFPVFENSERSSRHLPQAKAINPHHTASLSPAGR-- 86

Query: 68  GPTRP------------SGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAG 115
           G  RP            S + T RR  +A +A    P+   + S      W +      G
Sbjct: 87  GAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRG 146

Query: 116 PGLDCAGSA--------------PAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHS 161
            GL  A                 PAP+G +  GG   ++ L +      A GGG +G+ +
Sbjct: 147 RGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWK-----GAEGGGEKGNRN 201

Query: 162 GPRA--GTPGG-GRSSRAGARRKTPLSLCP-----------LKLRKGSSRRCQGLGSSWG 207
              A  G P      ++ G RR+ PL L P           ++      R   G   +  
Sbjct: 202 MAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEE 261

Query: 208 GSGTPPPPRALWNRH-----GGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGH 262
            +      R LW R       GA  AR   RG+      G        +AG  G      
Sbjct: 262 QAAGEAAARGLWRRKPAPCPRGACAARLGGRGT------GRARRAEFRVAGPRGVAEEAE 315

Query: 263 GGVQRQRFSAPSSHSTSGG----RPTG-ERSSREPLLDPSKAARASALPTARVAHASPPS 317
            G  R   S PS  + SGG     P G  R    P   P  A RA        A    P 
Sbjct: 316 SG--RGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARGLGPG 373

Query: 318 LAAAQWRLGGGK 329
                 R GGG+
Sbjct: 374 DRRGDGRFGGGR 385



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 81/328 (24%), Positives = 107/328 (32%), Gaps = 59/328 (17%)

Query: 156 GRGSHSGPRAGTPGG------GRSSRAGARRKTPLSLCPLKLRKGSS----RRCQGLGSS 205
           GRG+   P    P         R+ R G+  +   +  P  + +GS     R  QGLG  
Sbjct: 85  GRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPP 144

Query: 206 WG-GSGTPPPPRAL----------------WNRHGGAAGARAQVRGSEKRACPGSTLPPS 248
            G G  T PPP +L                    GG   +    +G+E     G+    +
Sbjct: 145 RGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGGEKGNRNMAA 204

Query: 249 SVLAGCVGTRARGHGGVQRQRF----------SAPSSHSTSGGRPTGERSSREPLLDPSK 298
           + L       A+   G++R+R           SAPS        P G       L +   
Sbjct: 205 APLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAP-GRSRVGAALTEEQA 263

Query: 299 AARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALE 358
           A  A+A    R   A  P  A A  RLGG        +G  R   +      PR     E
Sbjct: 264 AGEAAARGLWRRKPAPCPRGACAA-RLGG--------RGTGRARRAEFRVAGPRG--VAE 312

Query: 359 PAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPA--------RLRGGGGGS 410
            A+    W         SG    P P+    GK AP    PP         RLR    G 
Sbjct: 313 EAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAP--EEPPRVARRAHENRLRTSARGL 370

Query: 411 GLTQLVGSGRGSGVTHSVGTHALATRRG 438
           G     G GR  G   + G  +   R G
Sbjct: 371 GPGDRRGDGRFGGGRGAEGAGSGLPRGG 398


>gi|239743688 PREDICTED: hypothetical protein XP_002342946 [Homo
           sapiens]
          Length = 400

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 82/278 (29%), Positives = 99/278 (35%), Gaps = 38/278 (13%)

Query: 286 ERSSREPLLDPSKAAR----ASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRT 341
           ERSSR   L  +KA      AS  P  R A   P     +    G   R        +R 
Sbjct: 61  ERSSRH--LPQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAAR-------TLRR 111

Query: 342 DLSTAEEEDPR-SGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAP- 399
                + + PR +G A     G E W +        G  T P PS  R   P PR   P 
Sbjct: 112 GSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPA 171

Query: 400 PARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLS- 458
           PA  +G GGG     L     G G       +  A   G  A        G+   RPL  
Sbjct: 172 PAGGKGEGGGKESAVLWKGAEGGG--EKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLEL 229

Query: 459 --SPAPQSPPRSPSVRAF----GPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQR 512
              PA  S P SP +R F      R+GA  L+  QA   AA  G+    P+P        
Sbjct: 230 VPRPALPSAP-SPRIRCFLAPGRSRVGAA-LTEEQAAGEAAARGLWRRKPAPCPRGA--- 284

Query: 513 CEGCGGGSQPFAGRRAE---RGKRG------AGVPWRT 541
           C    GG      RRAE    G RG      +G  WR+
Sbjct: 285 CAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRS 322



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 93/372 (25%), Positives = 125/372 (33%), Gaps = 77/372 (20%)

Query: 20  LPSLGEKAL----TALSHQNP---EFPQIARNDCWDR-VPRGSVTDSNHT----PAGLDC 67
           +PSLG        T LS   P    FP    ++   R +P+    + +HT    PAG   
Sbjct: 29  IPSLGRNLHVSPGTVLSDLQPLGITFPVFENSERSSRHLPQAKAINPHHTASLSPAGR-- 86

Query: 68  GPTRP------------SGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAG 115
           G  RP            S + T RR  +A +A    P+   + S      W +      G
Sbjct: 87  GAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRG 146

Query: 116 PGLDCAGSA--------------PAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHS 161
            GL  A                 PAP+G +  GG   ++ L +      A GGG +G+ +
Sbjct: 147 RGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWK-----GAEGGGEKGNRN 201

Query: 162 GPRA--GTPGG-GRSSRAGARRKTPLSLCP-----------LKLRKGSSRRCQGLGSSWG 207
              A  G P      ++ G RR+ PL L P           ++      R   G   +  
Sbjct: 202 MAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEE 261

Query: 208 GSGTPPPPRALWNRH-----GGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGH 262
            +      R LW R       GA  AR   RG+      G        +AG  G      
Sbjct: 262 QAAGEAAARGLWRRKPAPCPRGACAARLGGRGT------GRARRAEFRVAGPRGVAEEAE 315

Query: 263 GGVQRQRFSAPSSHSTSGG----RPTG-ERSSREPLLDPSKAARASALPTARVAHASPPS 317
            G  R   S PS  + SGG     P G  R    P   P  A RA        A    P 
Sbjct: 316 SG--RGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARGLGPG 373

Query: 318 LAAAQWRLGGGK 329
                 R GGG+
Sbjct: 374 DRRGDGRFGGGR 385



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 81/328 (24%), Positives = 107/328 (32%), Gaps = 59/328 (17%)

Query: 156 GRGSHSGPRAGTPGG------GRSSRAGARRKTPLSLCPLKLRKGSS----RRCQGLGSS 205
           GRG+   P    P         R+ R G+  +   +  P  + +GS     R  QGLG  
Sbjct: 85  GRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPP 144

Query: 206 WG-GSGTPPPPRAL----------------WNRHGGAAGARAQVRGSEKRACPGSTLPPS 248
            G G  T PPP +L                    GG   +    +G+E     G+    +
Sbjct: 145 RGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGGEKGNRNMAA 204

Query: 249 SVLAGCVGTRARGHGGVQRQRF----------SAPSSHSTSGGRPTGERSSREPLLDPSK 298
           + L       A+   G++R+R           SAPS        P G       L +   
Sbjct: 205 APLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAP-GRSRVGAALTEEQA 263

Query: 299 AARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALE 358
           A  A+A    R   A  P  A A  RLGG        +G  R   +      PR     E
Sbjct: 264 AGEAAARGLWRRKPAPCPRGACAA-RLGG--------RGTGRARRAEFRVAGPRG--VAE 312

Query: 359 PAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPA--------RLRGGGGGS 410
            A+    W         SG    P P+    GK AP    PP         RLR    G 
Sbjct: 313 EAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAP--EEPPRVARRAHENRLRTSARGL 370

Query: 411 GLTQLVGSGRGSGVTHSVGTHALATRRG 438
           G     G GR  G   + G  +   R G
Sbjct: 371 GPGDRRGDGRFGGGRGAEGAGSGLPRGG 398


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 132/524 (25%), Positives = 166/524 (31%), Gaps = 76/524 (14%)

Query: 66  DCGPTRPSGSLTTRRPRDAGEAAVSG-PSRQRRTSRARTALWGRRSRRAAGPGLDCAGSA 124
           + GPT   G    + PR  GE    G P     +    T         A  PG+  A   
Sbjct: 376 EAGPTGARGPEGAQGPR--GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 433

Query: 125 PAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRA--------GTPG-GGRSSR 175
           P P G     GP  A+    P  Q    G  G     GP+         G PG  G   +
Sbjct: 434 PGPRGPP---GPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGK 490

Query: 176 AGARRKTPLSLCP--------------------LKLRKGS--SRRCQGLGSSWGGSGTP- 212
            GAR + P  + P                    L   KG+   R   GL    G +G P 
Sbjct: 491 RGARGE-PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG 549

Query: 213 -------PPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGV 265
                  P  R L  R G A G + +V  S      G   PP           ARG  GV
Sbjct: 550 RPGEPGLPGARGLTGRPGDA-GPQGKVGPSGAPGEDGRPGPPGP-------QGARGQPGV 601

Query: 266 QRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRL 325
               F  P   +   G+  GE+      L  +   R           A PP  A      
Sbjct: 602 MG--FPGPKGANGEPGK-AGEKG-----LPGAPGLRGLPGKDGETGAAGPPGPAGPAGER 653

Query: 326 GG-GKRKPTVLKGAVRTDLSTAEEEDPRS-GRALEPAQGSELWARAER----HGGSSGAR 379
           G  G   P+  +G         E   P   G   E      +  R ER      GS GA+
Sbjct: 654 GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQ 713

Query: 380 TLPTPSRARPGKPA---PRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATR 436
            L  P R  PG P    P+G++ PA   G  G  GL  + G    +G+    G       
Sbjct: 714 GLQGP-RGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGE 772

Query: 437 RGSRAPRPVGVLRGVPHFRPLSSPAPQ-SPPRSPSVRAFGPRLGAGRLSCPQAPRAAALP 495
           +G          RG+    P+  P P  +      V   GP   AG    P        P
Sbjct: 773 KGPEGAPGKDGGRGLT--GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP 830

Query: 496 GIAVLAPSPAHD-WGGQRCEGCGGGSQPFAGRRAERGKRGAGVP 538
           G A  A  P  D   G + E    G +  AG    +G  GA  P
Sbjct: 831 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP 874



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 44/132 (33%), Positives = 50/132 (37%), Gaps = 20/132 (15%)

Query: 51   PRGSVTDSNHTPAGLDCGPTRPSGSLTTRRPR----DAGEAAVSGPSRQRRTSRARTALW 106
            P G   D     A    GP+ P+G+   + P+    D GEA   G  R  +  R  T L 
Sbjct: 1081 PTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPG-ERGLKGHRGFTGLQ 1139

Query: 107  GRRSRRAAGPGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAG 166
            G       GP        P PSG Q   GPA  S  R P      SG  G     GP  G
Sbjct: 1140 G-----LPGP--------PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGP-IG 1185

Query: 167  TPG-GGRSSRAG 177
             PG  GRS   G
Sbjct: 1186 PPGPRGRSGETG 1197



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 130/527 (24%), Positives = 165/527 (31%), Gaps = 82/527 (15%)

Query: 51   PRGSV-TDSNHTPAGLDCGPTRPSGSL----TTRRPRDAGEAAVSGPSRQRRTSRARTAL 105
            PRG   T     P G   GP  P G+         P + G A ++GP   R         
Sbjct: 718  PRGLPGTPGTDGPKGAS-GPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV------ 770

Query: 106  WGRRSRRAA-----GPGLDCAGSAPAPSGAQS------CGGPAPASALRRPLTQWDASGG 154
             G +    A     G GL      P P+GA          GPA ++  R    +   +G 
Sbjct: 771  -GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP 829

Query: 155  GGRGSHSGPRA--GTPGG-------GRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSS 205
             G    +GP    G PG        G+   AGA      S  P        +   G+   
Sbjct: 830  PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP------GPQGPTGVTGP 883

Query: 206  WGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTR-ARGHGG 264
             G  G   PP A      G  GA  +V        PG   PP    +G  G + ARG  G
Sbjct: 884  KGARGAQGPPGAT-----GFPGAAGRVGPPGSNGNPGPPGPPGP--SGKDGPKGARGDSG 936

Query: 265  VQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWR 324
                R   P     +G  P GE+   EP  D    A     P           L   +  
Sbjct: 937  PPG-RAGEPGLQGPAG--PPGEKG--EPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGE 991

Query: 325  LG-GGKRKPTVLKGAVRTDLSTAEEEDPR-------SGRALEPAQGSELWARAERHGGSS 376
             G  G   P+   G      ++ +   P        +G A EP  G E    A+   G  
Sbjct: 992  RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP--GREGSPGADGPPGRD 1049

Query: 377  GARTLP-----TPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTH 431
            GA  +      T +   PG P P GS  PA   G  G  G     G    SG   + G  
Sbjct: 1050 GAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQ 1109

Query: 432  ALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAGRLSCPQAPRA 491
                 RG +        RG+   R  +       P  PS    G + GA   + P  PR 
Sbjct: 1110 GPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS----GDQ-GASGPAGPSGPRG 1164

Query: 492  AALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRGAGVP 538
                      P P    G     G  G   P  G R   G+ G   P
Sbjct: 1165 ---------PPGPVGPSGKDGANGIPGPIGP-PGPRGRSGETGPAGP 1201



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 132/537 (24%), Positives = 161/537 (29%), Gaps = 95/537 (17%)

Query: 36  PEFPQIARNDCWDRVPRGSVTDSNHT----PAGLDCGPTRPSGSLTTRRPRDAGEAAVSG 91
           P+ P   +    ++ PRG   D        P G D  P  P        P   G     G
Sbjct: 118 PKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGN------PGPPGPPGPPG 171

Query: 92  PSRQRRTSRARTALWGRRSRRAAGPGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDA 151
           P        A+ A  G    +A G  L        P G +   GPA A   +        
Sbjct: 172 PPGLGGNFAAQMA--GGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGE 229

Query: 152 SGGGGRGSHSGPRA--GTPGG-GRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGG 208
            G  G     GPR   G PG  G    AG            K  K   R   G   + G 
Sbjct: 230 PGEPGVSGPMGPRGPPGPPGKPGDDGEAG------------KPGKAGERGPPGPQGARGF 277

Query: 209 SGTPPPPRALWNR-HGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQR 267
            GTP  P    +R + G  GA+ +      +   GS  P  +   G +G R         
Sbjct: 278 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS--PGENGSPGPMGPRG-------- 327

Query: 268 QRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGG 327
                P     +G  P G   +R     P  A      P   V  A  P    A      
Sbjct: 328 ----LPGERGRTG--PAGAAGARGNDGQPGPAG-----PPGPVGPAGGPGFPGAPG--AK 374

Query: 328 GKRKPTVLKGAVRTDLSTAEEEDPRS----GRALEPAQGSELWARAERHGGSSGARTLPT 383
           G+  PT  +G         E   P S    G +  P       A+     GS+GA  +  
Sbjct: 375 GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK-----GSAGAPGIA- 428

Query: 384 PSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAP- 442
                PG P PRG   P    G  G  G T   G     G     G    A  +G+  P 
Sbjct: 429 ---GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 485

Query: 443 ----------RPVGV-------------LRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLG 479
                      P GV              RG P    L+ P      R PS  A GP+  
Sbjct: 486 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA-GPK-- 542

Query: 480 AGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGG--GSQPFAGRRAERGKRG 534
            G    P  P    LPG   L   P  D G Q   G  G  G     G    +G RG
Sbjct: 543 -GANGDPGRPGEPGLPGARGLTGRPG-DAGPQGKVGPSGAPGEDGRPGPPGPQGARG 597



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 53/193 (27%), Positives = 66/193 (34%), Gaps = 23/193 (11%)

Query: 357 LEPAQGSELWARAERHGGSSGARTLPTPSRARP-----GKPAPRGSAPPARLRGGGGGSG 411
           L+ A+G       +   GS G    P P   R      G+  P G+A      G  G +G
Sbjct: 295 LDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAG 354

Query: 412 LTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSV 471
               VG   G G   + G    A   G+R P      RG P      SP P     +P  
Sbjct: 355 PPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEP--GTPGSPGPAGASGNPGT 412

Query: 472 RAF-GPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGG-----GSQPFAG 525
               G +  AG      AP  A  PG     P P    G Q   G  G     G    AG
Sbjct: 413 DGIPGAKGSAG------APGIAGAPGF----PGPRGPPGPQGATGPLGPKGQTGEPGIAG 462

Query: 526 RRAERGKRGAGVP 538
            + E+G +G   P
Sbjct: 463 FKGEQGPKGEPGP 475


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 132/524 (25%), Positives = 166/524 (31%), Gaps = 76/524 (14%)

Query: 66  DCGPTRPSGSLTTRRPRDAGEAAVSG-PSRQRRTSRARTALWGRRSRRAAGPGLDCAGSA 124
           + GPT   G    + PR  GE    G P     +    T         A  PG+  A   
Sbjct: 307 EAGPTGARGPEGAQGPR--GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 364

Query: 125 PAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRA--------GTPG-GGRSSR 175
           P P G     GP  A+    P  Q    G  G     GP+         G PG  G   +
Sbjct: 365 PGPRGPP---GPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGK 421

Query: 176 AGARRKTPLSLCP--------------------LKLRKGS--SRRCQGLGSSWGGSGTP- 212
            GAR + P  + P                    L   KG+   R   GL    G +G P 
Sbjct: 422 RGARGE-PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG 480

Query: 213 -------PPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGV 265
                  P  R L  R G A G + +V  S      G   PP           ARG  GV
Sbjct: 481 RPGEPGLPGARGLTGRPGDA-GPQGKVGPSGAPGEDGRPGPPGP-------QGARGQPGV 532

Query: 266 QRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRL 325
               F  P   +   G+  GE+      L  +   R           A PP  A      
Sbjct: 533 MG--FPGPKGANGEPGK-AGEKG-----LPGAPGLRGLPGKDGETGAAGPPGPAGPAGER 584

Query: 326 GG-GKRKPTVLKGAVRTDLSTAEEEDPRS-GRALEPAQGSELWARAER----HGGSSGAR 379
           G  G   P+  +G         E   P   G   E      +  R ER      GS GA+
Sbjct: 585 GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQ 644

Query: 380 TLPTPSRARPGKPA---PRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATR 436
            L  P R  PG P    P+G++ PA   G  G  GL  + G    +G+    G       
Sbjct: 645 GLQGP-RGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGE 703

Query: 437 RGSRAPRPVGVLRGVPHFRPLSSPAPQ-SPPRSPSVRAFGPRLGAGRLSCPQAPRAAALP 495
           +G          RG+    P+  P P  +      V   GP   AG    P        P
Sbjct: 704 KGPEGAPGKDGGRGLT--GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP 761

Query: 496 GIAVLAPSPAHD-WGGQRCEGCGGGSQPFAGRRAERGKRGAGVP 538
           G A  A  P  D   G + E    G +  AG    +G  GA  P
Sbjct: 762 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP 805



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 44/132 (33%), Positives = 50/132 (37%), Gaps = 20/132 (15%)

Query: 51   PRGSVTDSNHTPAGLDCGPTRPSGSLTTRRPR----DAGEAAVSGPSRQRRTSRARTALW 106
            P G   D     A    GP+ P+G+   + P+    D GEA   G  R  +  R  T L 
Sbjct: 1012 PTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPG-ERGLKGHRGFTGLQ 1070

Query: 107  GRRSRRAAGPGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHSGPRAG 166
            G       GP        P PSG Q   GPA  S  R P      SG  G     GP  G
Sbjct: 1071 G-----LPGP--------PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGP-IG 1116

Query: 167  TPG-GGRSSRAG 177
             PG  GRS   G
Sbjct: 1117 PPGPRGRSGETG 1128



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 130/527 (24%), Positives = 165/527 (31%), Gaps = 82/527 (15%)

Query: 51   PRGSV-TDSNHTPAGLDCGPTRPSGSL----TTRRPRDAGEAAVSGPSRQRRTSRARTAL 105
            PRG   T     P G   GP  P G+         P + G A ++GP   R         
Sbjct: 649  PRGLPGTPGTDGPKGAS-GPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV------ 701

Query: 106  WGRRSRRAA-----GPGLDCAGSAPAPSGAQS------CGGPAPASALRRPLTQWDASGG 154
             G +    A     G GL      P P+GA          GPA ++  R    +   +G 
Sbjct: 702  -GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP 760

Query: 155  GGRGSHSGPRA--GTPGG-------GRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSS 205
             G    +GP    G PG        G+   AGA      S  P        +   G+   
Sbjct: 761  PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP------GPQGPTGVTGP 814

Query: 206  WGGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTR-ARGHGG 264
             G  G   PP A      G  GA  +V        PG   PP    +G  G + ARG  G
Sbjct: 815  KGARGAQGPPGAT-----GFPGAAGRVGPPGSNGNPGPPGPPGP--SGKDGPKGARGDSG 867

Query: 265  VQRQRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWR 324
                R   P     +G  P GE+   EP  D    A     P           L   +  
Sbjct: 868  PPG-RAGEPGLQGPAG--PPGEKG--EPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGE 922

Query: 325  LG-GGKRKPTVLKGAVRTDLSTAEEEDPR-------SGRALEPAQGSELWARAERHGGSS 376
             G  G   P+   G      ++ +   P        +G A EP  G E    A+   G  
Sbjct: 923  RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP--GREGSPGADGPPGRD 980

Query: 377  GARTLP-----TPSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTH 431
            GA  +      T +   PG P P GS  PA   G  G  G     G    SG   + G  
Sbjct: 981  GAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQ 1040

Query: 432  ALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAGRLSCPQAPRA 491
                 RG +        RG+   R  +       P  PS    G + GA   + P  PR 
Sbjct: 1041 GPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS----GDQ-GASGPAGPSGPRG 1095

Query: 492  AALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAERGKRGAGVP 538
                      P P    G     G  G   P  G R   G+ G   P
Sbjct: 1096 ---------PPGPVGPSGKDGANGIPGPIGP-PGPRGRSGETGPAGP 1132



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 132/537 (24%), Positives = 161/537 (29%), Gaps = 95/537 (17%)

Query: 36  PEFPQIARNDCWDRVPRGSVTDSNHT----PAGLDCGPTRPSGSLTTRRPRDAGEAAVSG 91
           P+ P   +    ++ PRG   D        P G D  P  P        P   G     G
Sbjct: 49  PKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGN------PGPPGPPGPPG 102

Query: 92  PSRQRRTSRARTALWGRRSRRAAGPGLDCAGSAPAPSGAQSCGGPAPASALRRPLTQWDA 151
           P        A+ A  G    +A G  L        P G +   GPA A   +        
Sbjct: 103 PPGLGGNFAAQMA--GGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGE 160

Query: 152 SGGGGRGSHSGPRA--GTPGG-GRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSSWGG 208
            G  G     GPR   G PG  G    AG            K  K   R   G   + G 
Sbjct: 161 PGEPGVSGPMGPRGPPGPPGKPGDDGEAG------------KPGKAGERGPPGPQGARGF 208

Query: 209 SGTPPPPRALWNR-HGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQR 267
            GTP  P    +R + G  GA+ +      +   GS  P  +   G +G R         
Sbjct: 209 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS--PGENGSPGPMGPRG-------- 258

Query: 268 QRFSAPSSHSTSGGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGG 327
                P     +G  P G   +R     P  A      P   V  A  P    A      
Sbjct: 259 ----LPGERGRTG--PAGAAGARGNDGQPGPAG-----PPGPVGPAGGPGFPGAPG--AK 305

Query: 328 GKRKPTVLKGAVRTDLSTAEEEDPRS----GRALEPAQGSELWARAERHGGSSGARTLPT 383
           G+  PT  +G         E   P S    G +  P       A+     GS+GA  +  
Sbjct: 306 GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK-----GSAGAPGIA- 359

Query: 384 PSRARPGKPAPRGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAP- 442
                PG P PRG   P    G  G  G T   G     G     G    A  +G+  P 
Sbjct: 360 ---GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 416

Query: 443 ----------RPVGV-------------LRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLG 479
                      P GV              RG P    L+ P      R PS  A GP+  
Sbjct: 417 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA-GPK-- 473

Query: 480 AGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGG--GSQPFAGRRAERGKRG 534
            G    P  P    LPG   L   P  D G Q   G  G  G     G    +G RG
Sbjct: 474 -GANGDPGRPGEPGLPGARGLTGRPG-DAGPQGKVGPSGAPGEDGRPGPPGPQGARG 528



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 53/193 (27%), Positives = 66/193 (34%), Gaps = 23/193 (11%)

Query: 357 LEPAQGSELWARAERHGGSSGARTLPTPSRARP-----GKPAPRGSAPPARLRGGGGGSG 411
           L+ A+G       +   GS G    P P   R      G+  P G+A      G  G +G
Sbjct: 226 LDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAG 285

Query: 412 LTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPAPQSPPRSPSV 471
               VG   G G   + G    A   G+R P      RG P      SP P     +P  
Sbjct: 286 PPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEP--GTPGSPGPAGASGNPGT 343

Query: 472 RAF-GPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGG-----GSQPFAG 525
               G +  AG      AP  A  PG     P P    G Q   G  G     G    AG
Sbjct: 344 DGIPGAKGSAG------APGIAGAPGF----PGPRGPPGPQGATGPLGPKGQTGEPGIAG 393

Query: 526 RRAERGKRGAGVP 538
            + E+G +G   P
Sbjct: 394 FKGEQGPKGEPGP 406


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,986,053
Number of Sequences: 37866
Number of extensions: 2027157
Number of successful extensions: 16160
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 131
Number of HSP's successfully gapped in prelim test: 1272
Number of HSP's that attempted gapping in prelim test: 11024
Number of HSP's gapped (non-prelim): 4941
length of query: 564
length of database: 18,247,518
effective HSP length: 108
effective length of query: 456
effective length of database: 14,157,990
effective search space: 6456043440
effective search space used: 6456043440
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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