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Search of human proteins with 169169468
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169169468 PREDICTED: similar to hCG1643231 [Homo sapiens]
(315 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169169468 PREDICTED: similar to hCG1643231 [Homo sapiens] 615 e-176
gi|169168829 PREDICTED: similar to hCG1643231 [Homo sapiens] 605 e-173
gi|4504919 keratin 8 [Homo sapiens] 259 2e-69
gi|226246665 keratin 72 isoform 2 [Homo sapiens] 194 9e-50
gi|119395754 keratin 5 [Homo sapiens] 170 1e-42
gi|5031839 keratin 6A [Homo sapiens] 166 2e-41
gi|155969697 keratin 6C [Homo sapiens] 164 7e-41
gi|119703753 keratin 6B [Homo sapiens] 164 9e-41
gi|32567786 keratin 6L [Homo sapiens] 157 2e-38
gi|15431316 keratin, hair, basic, 4 [Homo sapiens] 155 3e-38
gi|153791158 keratin 75 [Homo sapiens] 155 4e-38
gi|109148552 keratin 3 [Homo sapiens] 155 4e-38
gi|67782365 keratin 7 [Homo sapiens] 154 1e-37
gi|119395750 keratin 1 [Homo sapiens] 152 4e-37
gi|15618995 keratin 71 [Homo sapiens] 151 8e-37
gi|109255249 keratin 4 [Homo sapiens] 150 1e-36
gi|153791670 keratin 76 [Homo sapiens] 150 2e-36
gi|28372503 keratin 72 isoform 1 [Homo sapiens] 149 4e-36
gi|226246663 keratin 72 isoform 1 [Homo sapiens] 149 4e-36
gi|47132620 keratin 2 [Homo sapiens] 147 2e-35
gi|28173564 keratin 73 [Homo sapiens] 146 2e-35
gi|194018511 keratin 77 [Homo sapiens] 145 5e-35
gi|148612803 keratin 6 irs4 [Homo sapiens] 144 1e-34
gi|27477127 keratin 82 [Homo sapiens] 133 2e-31
gi|4504935 keratin 85 [Homo sapiens] 133 2e-31
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap... 129 4e-30
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap... 129 4e-30
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap... 129 4e-30
gi|14318422 keratin 86 [Homo sapiens] 129 4e-30
gi|169790853 keratin, hair, basic, 1 [Homo sapiens] 129 4e-30
>gi|169169468 PREDICTED: similar to hCG1643231 [Homo sapiens]
Length = 315
Score = 615 bits (1587), Expect = e-176
Identities = 315/315 (100%), Positives = 315/315 (100%)
Query: 1 MSIRVTQKSYKRLLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNN 60
MSIRVTQKSYKRLLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNN
Sbjct: 1 MSIRVTQKSYKRLLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNN 60
Query: 61 MLETKWSLLQQQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKN 120
MLETKWSLLQQQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKN
Sbjct: 61 MLETKWSLLQQQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKN 120
Query: 121 KYKDEINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKD 180
KYKDEINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKD
Sbjct: 121 KYKDEINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKD 180
Query: 181 ANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQN 240
ANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQN
Sbjct: 181 ANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQN 240
Query: 241 MSIHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVVKKIKT 300
MSIHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVVKKIKT
Sbjct: 241 MSIHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVVKKIKT 300
Query: 301 CDGKLVSESSDVLPK 315
CDGKLVSESSDVLPK
Sbjct: 301 CDGKLVSESSDVLPK 315
>gi|169168829 PREDICTED: similar to hCG1643231 [Homo sapiens]
Length = 313
Score = 605 bits (1560), Expect = e-173
Identities = 312/315 (99%), Positives = 313/315 (99%), Gaps = 2/315 (0%)
Query: 1 MSIRVTQKSYKRLLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNN 60
MSIRVTQKSYKRLLSLLNLEVDPNIQAVQEQEKE QIRTLNNKFASFIGKVRFLEQQNN
Sbjct: 1 MSIRVTQKSYKRLLSLLNLEVDPNIQAVQEQEKE--QIRTLNNKFASFIGKVRFLEQQNN 58
Query: 61 MLETKWSLLQQQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKN 120
MLETKWSLLQQQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKL+AELGNMQGLVEDFKN
Sbjct: 59 MLETKWSLLQQQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKN 118
Query: 121 KYKDEINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKD 180
KYKDEINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKD
Sbjct: 119 KYKDEINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKD 178
Query: 181 ANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQN 240
ANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQN
Sbjct: 179 ANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQN 238
Query: 241 MSIHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVVKKIKT 300
MSIHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVVKKIKT
Sbjct: 239 MSIHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVVKKIKT 298
Query: 301 CDGKLVSESSDVLPK 315
CDGKLVSESSDVLPK
Sbjct: 299 CDGKLVSESSDVLPK 313
>gi|4504919 keratin 8 [Homo sapiens]
Length = 483
Score = 259 bits (662), Expect = 2e-69
Identities = 151/233 (64%), Positives = 172/233 (73%), Gaps = 16/233 (6%)
Query: 83 FKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCTEMENEFILIRKD 142
++ N R + +++ Q K + EL ++ G D + K EI+ EM ++
Sbjct: 267 YEDIANRSRAEAESMYQIKYE---ELQSLAGKHGDDLRRTKTEIS---EMNRNISRLQ-- 318
Query: 143 MDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQ 202
AE EGLK QRASLEA IAD +QRGELAIKDAN KLS+LEAALQ+A QDMA Q
Sbjct: 319 --------AEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQ 370
Query: 203 LHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAYADGLSLAYGGL 262
L EYQ+L N+KLALDIEIATYRKLLE EES LESGMQNMSIHTKTTS YA GLS AYGGL
Sbjct: 371 LREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSGYAGGLSSAYGGL 430
Query: 263 TSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVVKKIKTCDGKLVSESSDVLPK 315
TSPGLSY LGSSFGS GSSSFS TSS+RA+VVKKI+T DGKLVSESSDVLPK
Sbjct: 431 TSPGLSYSLGSSFGSGAGSSSFSRTSSSRAVVVKKIETRDGKLVSESSDVLPK 483
Score = 221 bits (564), Expect = 5e-58
Identities = 123/180 (68%), Positives = 142/180 (78%), Gaps = 5/180 (2%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LLS L LEVDPNIQAV+ QEKE QI+TLNNKFASFI KVRFLEQQN MLETKWSLLQQQ
Sbjct: 72 LLSPLVLEVDPNIQAVRTQEKE--QIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQ 129
Query: 73 KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCTEM 132
K A SNM NMF+SYINN R Q +TL QEKLKLEAELGNMQGLVEDFKNKY+DEINK TEM
Sbjct: 130 KTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEM 189
Query: 133 ENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAAL 192
ENEF+LI+KD+D+AY+NK E L+S+ L I ++Q E I++ +++S L
Sbjct: 190 ENEFVLIKKDVDEAYMNKVE---LESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVL 246
>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
Length = 469
Score = 194 bits (493), Expect = 9e-50
Identities = 137/366 (37%), Positives = 198/366 (54%), Gaps = 90/366 (24%)
Query: 11 KRLLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQ 70
K LL+ LN+E+DP IQ V+ QE+E QI+ LNNKFASFI KVRFLEQQN +LETKW+LLQ
Sbjct: 104 KSLLAPLNVEMDPEIQRVRAQERE--QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQ 161
Query: 71 QQKM--AWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINK 128
Q + N+ +++ YI+N + Q + L + ++L++EL NMQ LVED+K +Y+ EIN+
Sbjct: 162 QLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINR 221
Query: 129 CTEMENEFILIRKDMDDAYVNKAE--------TEGLK----------------------- 157
T ENEF++++KD+D AY+NK E T+ +K
Sbjct: 222 RTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIV 281
Query: 158 -----SQRASLEATIADVK-QRGELAIK-------------------------------- 179
++ L++ IA+V+ Q E+A+K
Sbjct: 282 LSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKCADLETAIADAEQRGDCALK 341
Query: 180 DANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQ 239
DA KL +LE AL QA +++A L EYQ+L ++KLALD+EIATYRKLLESEE +
Sbjct: 342 DARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRM----- 396
Query: 240 NMSIHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVVKKIK 299
+ Y + +S++ T+ G G+ F G+SS S + T A VK
Sbjct: 397 --------SGEYPNSVSISVISSTNAGAG---GAGFSMGFGASS-SYSYKTAAADVKTKG 444
Query: 300 TCDGKL 305
+C +L
Sbjct: 445 SCGSEL 450
>gi|119395754 keratin 5 [Homo sapiens]
Length = 590
Score = 170 bits (431), Expect = 1e-42
Identities = 87/144 (60%), Positives = 115/144 (79%), Gaps = 4/144 (2%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL+ LNL++DP+IQ V+ +E+E QI+TLNNKFASFI KVRFLEQQN +L+TKW+LLQ+Q
Sbjct: 149 LLTPLNLQIDPSIQRVRTEERE--QIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQ 206
Query: 73 --KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCT 130
K N+ +F+ YINN R Q D++V E+ +L++EL NMQ LVEDFKNKY+DEINK T
Sbjct: 207 GTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRT 266
Query: 131 EMENEFILIRKDMDDAYVNKAETE 154
ENEF++++KD+D AY+NK E E
Sbjct: 267 TAENEFVMLKKDVDAAYMNKVELE 290
Score = 120 bits (302), Expect = 1e-27
Identities = 82/209 (39%), Positives = 111/209 (53%), Gaps = 20/209 (9%)
Query: 83 FKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCTEMENEFILIRKD 142
++ N R + ++ Q K + + G +D +N K EI++ M
Sbjct: 346 YEEIANRSRTEAESWYQTKYEELQQTAGRHG--DDLRNT-KHEISEMNRMIQRL------ 396
Query: 143 MDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQ 202
+AE + +K Q A+L+ IAD +QRGELA+KDA KL++LE ALQ+A QDMA
Sbjct: 397 -------RAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARL 449
Query: 203 LHEYQKLKNMKLALDIEIATYRKLLESEESHLES---GMQNMSIHTKTTSAYADGLSLAY 259
L EYQ+L N KLALD+EIATYRKLLE EE L G N+S+ T + S+ G Y
Sbjct: 450 LREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSS-GYGSGSGY 508
Query: 260 GGLTSPGLSYGLGSSFGSDMGSSSFSCTS 288
GG GL GLG S +S +S
Sbjct: 509 GGGLGGGLGGGLGGGLAGGSSGSYYSSSS 537
>gi|5031839 keratin 6A [Homo sapiens]
Length = 564
Score = 166 bits (421), Expect = 2e-41
Identities = 86/144 (59%), Positives = 112/144 (77%), Gaps = 4/144 (2%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL+ LNL++DP IQ V+ +E+E QI+TLNNKFASFI KVRFLEQQN +LETKW+LLQ+Q
Sbjct: 144 LLTPLNLQIDPTIQRVRAEERE--QIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQ 201
Query: 73 --KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCT 130
K N+ +F+ YINN R Q D++V E+ +L++EL MQ LVEDFKNKY+DEINK T
Sbjct: 202 GTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRT 261
Query: 131 EMENEFILIRKDMDDAYVNKAETE 154
ENEF+ ++KD+D AY+NK E +
Sbjct: 262 AAENEFVTLKKDVDAAYMNKVELQ 285
Score = 118 bits (296), Expect = 6e-27
Identities = 72/151 (47%), Positives = 94/151 (62%), Gaps = 14/151 (9%)
Query: 150 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 209
++E + +K Q A+L+A IAD +QRGE+A+KDA KL LE ALQ+A QD+A L EYQ+L
Sbjct: 392 RSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQEL 451
Query: 210 KNMKLALDIEIATYRKLLESEESHLES---GMQNMSIHTKTTSAYADGLSLAYGGLTSPG 266
N+KLALD+EIATYRKLLE EE L G N+S+ T S+ YGG + G
Sbjct: 452 MNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSS-------GYGGASGVG 504
Query: 267 LSYGLGS----SFGSDMGSSSFSCTSSTRAM 293
GLG S+GS +G +SS RA+
Sbjct: 505 SGLGLGGGSSYSYGSGLGVGGGFSSSSGRAI 535
>gi|155969697 keratin 6C [Homo sapiens]
Length = 564
Score = 164 bits (416), Expect = 7e-41
Identities = 85/144 (59%), Positives = 112/144 (77%), Gaps = 4/144 (2%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL+ LNL++DP IQ V+ +E+E QI+TLNNKFASFI KVRFLEQQN +L+TKW+LLQ+Q
Sbjct: 144 LLTPLNLQIDPAIQRVRAEERE--QIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQ 201
Query: 73 --KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCT 130
K N+ +F+ YINN R Q D++V E+ +L++EL NMQ LVED KNKY+DEINK T
Sbjct: 202 GTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRT 261
Query: 131 EMENEFILIRKDMDDAYVNKAETE 154
ENEF+ ++KD+D AY+NK E +
Sbjct: 262 AAENEFVTLKKDVDAAYMNKVELQ 285
Score = 119 bits (298), Expect = 3e-27
Identities = 73/151 (48%), Positives = 94/151 (62%), Gaps = 14/151 (9%)
Query: 150 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 209
++E + +K Q ASL+A IAD +QRGE+A+KDA KL LE ALQ+A QD+A L EYQ+L
Sbjct: 392 RSEIDHVKKQCASLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQEL 451
Query: 210 KNMKLALDIEIATYRKLLESEESHLES---GMQNMSIHTKTTSAYADGLSLAYGGLTSPG 266
N+KLALD+EIATYRKLLE EE L G N+S+ T +S YGG + G
Sbjct: 452 MNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNVSVVQST-------ISSGYGGASGVG 504
Query: 267 LSYGLGS----SFGSDMGSSSFSCTSSTRAM 293
GLG S+GS +G +SS RA+
Sbjct: 505 SGLGLGGGSSYSYGSGLGIGGGFSSSSGRAI 535
>gi|119703753 keratin 6B [Homo sapiens]
Length = 564
Score = 164 bits (415), Expect = 9e-41
Identities = 85/144 (59%), Positives = 111/144 (77%), Gaps = 4/144 (2%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL+ LNL++DP IQ V+ +E+E QI+TLNNKFASFI KVRFLEQQN +L+TKW+LLQ+Q
Sbjct: 144 LLTPLNLQIDPAIQRVRAEERE--QIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQ 201
Query: 73 --KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCT 130
K N+ +F+ YINN R Q D +V E+ +L++EL NMQ LVED KNKY+DEINK T
Sbjct: 202 GTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRT 261
Query: 131 EMENEFILIRKDMDDAYVNKAETE 154
ENEF+ ++KD+D AY+NK E +
Sbjct: 262 AAENEFVTLKKDVDAAYMNKVELQ 285
Score = 118 bits (295), Expect = 8e-27
Identities = 72/150 (48%), Positives = 93/150 (62%), Gaps = 14/150 (9%)
Query: 150 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 209
++E + +K Q A+L+A IAD +QRGE+A+KDA KL LE ALQ+A QD+A L EYQ+L
Sbjct: 392 RSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQEL 451
Query: 210 KNMKLALDIEIATYRKLLESEESHLES---GMQNMSIHTKTTSAYADGLSLAYGGLTSPG 266
N+KLALD+EIATYRKLLE EE L G N+S+ T S+ YGG + G
Sbjct: 452 MNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSS-------GYGGASGVG 504
Query: 267 LSYGLGS----SFGSDMGSSSFSCTSSTRA 292
GLG S+GS +G +SS RA
Sbjct: 505 SGLGLGGGSSYSYGSGLGVGGGFSSSSGRA 534
>gi|32567786 keratin 6L [Homo sapiens]
Length = 535
Score = 157 bits (396), Expect = 2e-38
Identities = 86/184 (46%), Positives = 125/184 (67%), Gaps = 9/184 (4%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL+ L++E+DP IQ V+ QE+E QI+TLNNKFASFI KVRFLEQQN +LETKW+LLQ+Q
Sbjct: 123 LLTPLHVEIDPEIQRVRTQERE--QIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQ 180
Query: 73 K----MAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINK 128
+ +N+ +F++Y+ + R D L E+ +L++EL N+Q LVEDFKNKY+DEINK
Sbjct: 181 GQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINK 240
Query: 129 CTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKL 188
T ENEF++++KD+D AY+ + + G + +L I ++Q E+ + T +S
Sbjct: 241 HTAAENEFVVLKKDVDAAYMGRMDLHG---KVGTLTQEIDFLQQLYEMELSQVQTHVSNT 297
Query: 189 EAAL 192
L
Sbjct: 298 NVVL 301
Score = 108 bits (269), Expect = 8e-24
Identities = 83/251 (33%), Positives = 127/251 (50%), Gaps = 18/251 (7%)
Query: 50 GKVRFLEQQNNMLETKWSLLQQQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELG 109
GKV L Q+ + L+ + + Q + N+ S NN D+++ E +K + EL
Sbjct: 267 GKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAE-VKAQYELI 325
Query: 110 NMQGLVED---FKNKYKD-------EINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQ 159
+ E ++ KY++ + + +NE + + + + E + K Q
Sbjct: 326 AQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRL---QGEADAAKKQ 382
Query: 160 RASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIE 219
L+ IA+ +QRGELA+KDA KL L+ AL QA +D+ L +YQ+L N+KLALD+E
Sbjct: 383 CQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVE 442
Query: 220 IATYRKLLESEESHLESGMQNMSIHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDM 279
IATYRKLLESEES + SG ++ T + ++ GG S G LG S G+
Sbjct: 443 IATYRKLLESEESRM-SGECPSAVSISVT---GNSTTVCGGGAASFGGGISLGGSGGATK 498
Query: 280 GSSSFSCTSST 290
G S + ST
Sbjct: 499 GGFSTNVGYST 509
>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
Length = 600
Score = 155 bits (393), Expect = 3e-38
Identities = 78/144 (54%), Positives = 108/144 (75%), Gaps = 2/144 (1%)
Query: 11 KRLLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQ 70
K LL+ LNLE+DPN Q V++ EKE QI+TLNNKFASFI KVRFLEQQN +LETKWS LQ
Sbjct: 144 KSLLTPLNLEIDPNAQRVKKDEKE--QIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQ 201
Query: 71 QQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCT 130
+QK SN+ +F+SYI N R Q + LV ++ +L+AE ++Q ++E FK KY++E+
Sbjct: 202 EQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRA 261
Query: 131 EMENEFILIRKDMDDAYVNKAETE 154
ENEF+ ++KD+D A++NK++ E
Sbjct: 262 NAENEFVALKKDVDAAFMNKSDLE 285
Score = 110 bits (275), Expect = 2e-24
Identities = 68/146 (46%), Positives = 89/146 (60%), Gaps = 13/146 (8%)
Query: 150 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 209
KAE E K+QRA LEA +A+ +Q+GE + DA KL+ LE ALQQA QDMA QL EYQ+L
Sbjct: 392 KAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQEL 451
Query: 210 KNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTT--------SAYADGLSLAYGG 261
N KL LDIEIATYR+LLE EES L G+ ++I ++ G +L+ GG
Sbjct: 452 MNAKLGLDIEIATYRRLLEGEESRLCEGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRGG 511
Query: 262 LTSPGLS-----YGLGSSFGSDMGSS 282
+T G S G+ +S G +G +
Sbjct: 512 VTFSGSSSVCATSGVLASCGPSLGGA 537
>gi|153791158 keratin 75 [Homo sapiens]
Length = 551
Score = 155 bits (392), Expect = 4e-38
Identities = 81/144 (56%), Positives = 109/144 (75%), Gaps = 4/144 (2%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL+ L+L++DP IQ V+ +E+E QI+TLNNKFASFI KVRFLEQQN +LETKW+LLQ+Q
Sbjct: 130 LLTPLHLQIDPTIQRVRAEERE--QIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQ 187
Query: 73 --KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCT 130
+ N+ +F SY + R Q +++ E+ +LEAEL NMQ +VEDFK +Y+DEINK T
Sbjct: 188 GSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRT 247
Query: 131 EMENEFILIRKDMDDAYVNKAETE 154
ENEF+ ++KD+D AY+NK E E
Sbjct: 248 AAENEFVALKKDVDAAYMNKVELE 271
Score = 123 bits (308), Expect = 2e-28
Identities = 89/219 (40%), Positives = 115/219 (52%), Gaps = 31/219 (14%)
Query: 83 FKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCTEMENEFILIRKD 142
++ N R + ++ Q K + EL G D K EI++ M
Sbjct: 327 YEDIANRSRAEAESWYQTKYE---ELQVTAGRHGDDLRNTKQEISEMNRMIQRL------ 377
Query: 143 MDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQ 202
+AE + +K Q +SL+ IAD +QRGELA+KDA KL LE ALQ+A QDMA
Sbjct: 378 -------RAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARL 430
Query: 203 LHEYQKLKNMKLALDIEIATYRKLLESEESHLES---GMQNMSIHTKT-TSAYADGLSLA 258
L EYQ+L N+KLALD+EIATYRKLLE EE L N+S+ T T +S Y G S+
Sbjct: 431 LREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYGSGSSIG 490
Query: 259 YGGLTSPGLSYGLGSSF--------GSDMGSSSFSCTSS 289
G L GL G G SF G+ +G S FS TS+
Sbjct: 491 GGNL---GLGGGSGYSFTTSGGHSLGAGLGGSGFSATSN 526
>gi|109148552 keratin 3 [Homo sapiens]
Length = 628
Score = 155 bits (392), Expect = 4e-38
Identities = 81/146 (55%), Positives = 109/146 (74%), Gaps = 6/146 (4%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL LN+E+DP I V+ QE+E QI+TLNNKFASFI KVRFLEQQN +LETKW+LLQQQ
Sbjct: 179 LLQPLNVEIDPQIGQVKAQERE--QIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQ 236
Query: 73 KMA----WSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINK 128
+ +N+ +F+++IN R D ++ E+ +L++EL NM+ LVEDFK KY+DEINK
Sbjct: 237 GTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINK 296
Query: 129 CTEMENEFILIRKDMDDAYVNKAETE 154
T ENEF+ ++KD+D AY+NK E +
Sbjct: 297 RTAAENEFVTLKKDVDSAYMNKVELQ 322
Score = 124 bits (311), Expect = 1e-28
Identities = 81/204 (39%), Positives = 116/204 (56%), Gaps = 15/204 (7%)
Query: 85 SYINNPRGQPDTLVQE-KLKLEAELGNMQGLVEDFKNKYKDEINKCTEMENEFILIRKDM 143
S I R Q + + Q K + EA G ++ ++ D++ ++E I + + +
Sbjct: 369 SIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNT---KSEIIELNRMI 425
Query: 144 DDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQL 203
+AE EG+K Q A+L+ IA+ +Q GE+A+KDAN KL +L+AALQQA D+A L
Sbjct: 426 QRL---RAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLL 482
Query: 204 HEYQKLKNMKLALDIEIATYRKLLESEESHLE----SGMQNMSIHTKTTSAYADGLSLAY 259
+YQ+L N+KLALD+EIATYRKLLE EE + S + + + TTSA A G Y
Sbjct: 483 RDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGY 542
Query: 260 GGLTSPGLSYGLGSSFGSDMGSSS 283
GG G+ GLG F + GS S
Sbjct: 543 GG----GMGGGLGGGFSAGGGSGS 562
>gi|67782365 keratin 7 [Homo sapiens]
Length = 469
Score = 154 bits (388), Expect = 1e-37
Identities = 81/143 (56%), Positives = 111/143 (77%), Gaps = 3/143 (2%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL+ L L+ DP++Q V+++E E QI+TLNNKFASFI KVRFLEQQN +LETKW+LLQ+Q
Sbjct: 72 LLAPLRLDADPSLQRVRQEESE--QIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQ 129
Query: 73 KMAWSN-MGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCTE 131
K A S+ + ++F++ I RGQ + L + +LEAEL +MQ +VEDFKNKY+DEIN T
Sbjct: 130 KSAKSSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTA 189
Query: 132 MENEFILIRKDMDDAYVNKAETE 154
ENEF++++KD+D AY++K E E
Sbjct: 190 AENEFVVLKKDVDAAYMSKVELE 212
Score = 122 bits (306), Expect = 4e-28
Identities = 74/150 (49%), Positives = 97/150 (64%), Gaps = 18/150 (12%)
Query: 150 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 209
+AE + +K+QRA LEA IA+ ++RGELA+KDA K +LEAALQ+ QDMA QL EYQ+L
Sbjct: 319 QAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQEL 378
Query: 210 KNMKLALDIEIATYRKLLESEESHLES---GMQNMSIHTKTTSAYADGLSLAYGGLTSPG 266
++KLALDIEIATYRKLLE EES L G N+S+ T GG +S G
Sbjct: 379 MSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNST------------GGSSSGG 426
Query: 267 LSYGLGSSFGSDMGSSSFSCTSSTRAMVVK 296
G+G + G MGS++ S +SS ++K
Sbjct: 427 ---GIGLTLGGTMGSNALSFSSSAGPGLLK 453
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 152 bits (384), Expect = 4e-37
Identities = 96/238 (40%), Positives = 140/238 (58%), Gaps = 33/238 (13%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL LN+E+DP IQ V+ +E+EQI++LNN+FASFI KVRFLEQQN +L+TKW LLQQ
Sbjct: 161 LLQPLNVEIDPEIQKVKS--REREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQV 218
Query: 73 KMAWS--NMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCT 130
+ N+ F+S+INN R + D L ++ +L++EL NMQ +VED++NKY+DEINK T
Sbjct: 219 DTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRT 278
Query: 131 EMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEA 190
ENEF+ I+KD+D AY+ K + L+A + +++Q ++ L A
Sbjct: 279 NAENEFVTIKKDVDGAYMTKVD----------LQAKLDNLQQ-----------EIDFLTA 317
Query: 191 ALQQAMQDMAWQLHEYQKL----KNMKLALDIEI----ATYRKLLESEESHLESGMQN 240
Q + M Q+ E + N L LD I A Y + + ++ ES Q+
Sbjct: 318 LYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQS 375
Score = 103 bits (258), Expect = 2e-22
Identities = 63/134 (47%), Positives = 85/134 (63%), Gaps = 6/134 (4%)
Query: 150 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 209
++E + +K Q ++L+ +I+D +QRGE A+KDA KL+ LE ALQQA +D+A L +YQ+L
Sbjct: 409 RSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQEL 468
Query: 210 KNMKLALDIEIATYRKLLESEESHLESG-MQNMSIHTKTTSAYADGLSLAYGGLTSPGLS 268
N KLALD+EIATYR LLE EES + N+S+ T+ G GG G
Sbjct: 469 MNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGG----GGG 524
Query: 269 YGL-GSSFGSDMGS 281
YG GSS+GS GS
Sbjct: 525 YGSGGSSYGSGGGS 538
>gi|15618995 keratin 71 [Homo sapiens]
Length = 523
Score = 151 bits (381), Expect = 8e-37
Identities = 82/169 (48%), Positives = 117/169 (69%), Gaps = 12/169 (7%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL+ LN+E+DP IQ V+ QE+E QI+ LNNKFASFI KVRFLEQQN +LETKW LLQQ
Sbjct: 111 LLAPLNVELDPEIQKVRAQERE--QIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQL 168
Query: 73 KM--AWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCT 130
+ +N+ + + YI+N R Q +TL ++++L++EL N++ +VED+K +Y++EINK T
Sbjct: 169 DLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRT 228
Query: 131 EMENEFILIRKDMDDAYVNKAETEG--------LKSQRASLEATIADVK 171
ENEF+L++KD+D AY NK E + +K R EA I ++
Sbjct: 229 AAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQ 277
Score = 101 bits (251), Expect = 1e-21
Identities = 69/196 (35%), Positives = 103/196 (52%), Gaps = 31/196 (15%)
Query: 116 EDFKNKYKDEINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGE 175
+D KN K+EI++ T + ++E E +K Q ++LE IAD +QRG+
Sbjct: 339 DDLKNT-KNEISELTRLIQRI-------------RSEIENVKKQASNLETAIADAEQRGD 384
Query: 176 LAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLE 235
A+KDA KL +LE AL QA +++A L EYQ+L ++KLALD+EIATYRKLLESEE +
Sbjct: 385 NALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRM- 443
Query: 236 SGMQNMSIHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVV 295
+ + +S++ TS G YG F M S + SS V
Sbjct: 444 ------------SGEFPSPVSISIISSTSGGSVYG----FRPSMVSGGYVANSSNCISGV 487
Query: 296 KKIKTCDGKLVSESSD 311
++ +G+ ++D
Sbjct: 488 CSVRGGEGRSRGSAND 503
>gi|109255249 keratin 4 [Homo sapiens]
Length = 594
Score = 150 bits (380), Expect = 1e-36
Identities = 79/144 (54%), Positives = 109/144 (75%), Gaps = 4/144 (2%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL+ L++E+DP IQ V+ +E+E QI+ LNNKFASFI KV+FLEQQN +LETKW+LLQQQ
Sbjct: 192 LLTPLHVEIDPEIQKVRTEERE--QIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQ 249
Query: 73 KMAWS--NMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCT 130
S N+ +F++Y++ R Q DTL +K +L++EL MQ VEDFK KY++EINK T
Sbjct: 250 TTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRT 309
Query: 131 EMENEFILIRKDMDDAYVNKAETE 154
EN+F++++KD+D AY+NK E E
Sbjct: 310 AAENDFVVLKKDVDAAYLNKVELE 333
Score = 115 bits (289), Expect = 4e-26
Identities = 69/144 (47%), Positives = 95/144 (65%), Gaps = 2/144 (1%)
Query: 150 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 209
+AE E +K Q +L+ ++AD +QRGE A+KDA++K +LEAALQQA +++A L EYQ+L
Sbjct: 440 RAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQEL 499
Query: 210 KNMKLALDIEIATYRKLLESEESHLESGMQN-MSIHTKTTSAYADGLSLAYGGLTSPGLS 268
++KLALDIEIATYRKLLE EE + Q+ +SI + S G+S G + GLS
Sbjct: 500 MSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLS 559
Query: 269 YGLGSSFGSDMG-SSSFSCTSSTR 291
G GS GS G S S +SS++
Sbjct: 560 SGFGSGSGSGFGFGGSVSGSSSSK 583
>gi|153791670 keratin 76 [Homo sapiens]
Length = 638
Score = 150 bits (378), Expect = 2e-36
Identities = 89/182 (48%), Positives = 120/182 (65%), Gaps = 7/182 (3%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL LN+E+DP I V+ QE+E QI+TLNNKFASFI KVRFLEQQN +LETKW LLQQQ
Sbjct: 164 LLQPLNVEIDPQIGQVKAQERE--QIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQ 221
Query: 73 KMAW--SNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCT 130
S++ F+SYI+ Q D+L+ E+ LE EL +MQ LVEDFK KY+DEINK T
Sbjct: 222 TTGSGPSSLEPCFESYISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRT 281
Query: 131 EMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEA 190
ENEF+ ++KD+D A++NK E L+++ SL ++ ++ E+ + + S
Sbjct: 282 AAENEFVGLKKDVDAAFMNKVE---LQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSV 338
Query: 191 AL 192
L
Sbjct: 339 VL 340
Score = 108 bits (269), Expect = 8e-24
Identities = 81/232 (34%), Positives = 113/232 (48%), Gaps = 29/232 (12%)
Query: 55 LEQQNNMLETKWSLLQQQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGL 114
L NN S++ + + + + KS + + L Q KL EL G
Sbjct: 340 LSMDNNRCLDLGSIIAEVRAQYEEIAQRSKS-------EAEALYQTKL---GELQTTAGR 389
Query: 115 VEDFKNKYKDEINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRG 174
D K EI + M +AE E +K Q A+L+ IA+ +QRG
Sbjct: 390 HGDDLRNTKSEIMELNRMIQRL-------------RAEIENVKKQNANLQTAIAEAEQRG 436
Query: 175 ELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHL 234
E+A+KDAN KL L+ ALQ+A D+A L +YQ+L N+KLALD+EIATYRKLLE EE +
Sbjct: 437 EMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRM 496
Query: 235 ESGMQN---MSIHTKTTSAYADGLSL--AYGGLTSPGL-SYGLGSSFGSDMG 280
Q+ +S+ + TS S +GG++ G Y GSS S G
Sbjct: 497 SGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSG 548
>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 149 bits (375), Expect = 4e-36
Identities = 103/291 (35%), Positives = 154/291 (52%), Gaps = 48/291 (16%)
Query: 11 KRLLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQ 70
K LL+ LN+E+DP IQ V+ QE+E QI+ LNNKFASFI KVRFLEQQN +LETKW+LLQ
Sbjct: 104 KSLLAPLNVEMDPEIQRVRAQERE--QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQ 161
Query: 71 QQKM--AWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINK 128
Q + N+ +++ YI+N + Q + L + ++L++EL NMQ LVED+K +Y+ EIN+
Sbjct: 162 QLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINR 221
Query: 129 CTEMENEFILIRKDMDDAYVNKAE--------TEGLK----------------------- 157
T ENEF++++KD+D AY+NK E T+ +K
Sbjct: 222 RTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIV 281
Query: 158 -----SQRASLEATIADVK-QRGELAIKDA-------NTKLSKLEAALQQAMQDMAWQLH 204
++ L++ IA+V+ Q E+A+K TK+ +L+ Q D+
Sbjct: 282 LSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKA 341
Query: 205 EYQKLKNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAYADGL 255
E +L + + EI +K E+ + Q K A D L
Sbjct: 342 EISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDEL 392
Score = 101 bits (251), Expect = 1e-21
Identities = 64/156 (41%), Positives = 90/156 (57%), Gaps = 17/156 (10%)
Query: 150 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 209
++E +K Q A LE IAD +QRG+ A+KDA KL +LE AL QA +++A L EYQ+L
Sbjct: 354 RSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQEL 413
Query: 210 KNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAYADGLSLAYGGLTSPGLSY 269
++KLALD+EIATYRKLLESEE + + Y + +S++ T+ G
Sbjct: 414 VSLKLALDMEIATYRKLLESEECRM-------------SGEYPNSVSISVISSTNAGAG- 459
Query: 270 GLGSSFGSDMGSSSFSCTSSTRAMVVKKIKTCDGKL 305
G+ F G+SS S + T A VK +C +L
Sbjct: 460 --GAGFSMGFGASS-SYSYKTAAADVKTKGSCGSEL 492
>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 149 bits (375), Expect = 4e-36
Identities = 103/291 (35%), Positives = 154/291 (52%), Gaps = 48/291 (16%)
Query: 11 KRLLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQ 70
K LL+ LN+E+DP IQ V+ QE+E QI+ LNNKFASFI KVRFLEQQN +LETKW+LLQ
Sbjct: 104 KSLLAPLNVEMDPEIQRVRAQERE--QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQ 161
Query: 71 QQKM--AWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINK 128
Q + N+ +++ YI+N + Q + L + ++L++EL NMQ LVED+K +Y+ EIN+
Sbjct: 162 QLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINR 221
Query: 129 CTEMENEFILIRKDMDDAYVNKAE--------TEGLK----------------------- 157
T ENEF++++KD+D AY+NK E T+ +K
Sbjct: 222 RTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIV 281
Query: 158 -----SQRASLEATIADVK-QRGELAIKDA-------NTKLSKLEAALQQAMQDMAWQLH 204
++ L++ IA+V+ Q E+A+K TK+ +L+ Q D+
Sbjct: 282 LSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKA 341
Query: 205 EYQKLKNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAYADGL 255
E +L + + EI +K E+ + Q K A D L
Sbjct: 342 EISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDEL 392
Score = 101 bits (251), Expect = 1e-21
Identities = 64/156 (41%), Positives = 90/156 (57%), Gaps = 17/156 (10%)
Query: 150 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 209
++E +K Q A LE IAD +QRG+ A+KDA KL +LE AL QA +++A L EYQ+L
Sbjct: 354 RSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQEL 413
Query: 210 KNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAYADGLSLAYGGLTSPGLSY 269
++KLALD+EIATYRKLLESEE + + Y + +S++ T+ G
Sbjct: 414 VSLKLALDMEIATYRKLLESEECRM-------------SGEYPNSVSISVISSTNAGAG- 459
Query: 270 GLGSSFGSDMGSSSFSCTSSTRAMVVKKIKTCDGKL 305
G+ F G+SS S + T A VK +C +L
Sbjct: 460 --GAGFSMGFGASS-SYSYKTAAADVKTKGSCGSEL 492
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 147 bits (370), Expect = 2e-35
Identities = 84/184 (45%), Positives = 118/184 (64%), Gaps = 16/184 (8%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL LN++VDP IQ V+ QE+E QI+TLNNKFASFI KVRFLEQQN +L+TKW LLQQ
Sbjct: 159 LLQPLNVKVDPEIQNVKAQERE--QIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQM 216
Query: 73 KMAWS--NMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCT 130
+ N+ +F+ YI++ + D L E+ +EL NMQ LVED+K KY+DEINK T
Sbjct: 217 NVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRT 276
Query: 131 EMENEFILIRKDMDDAYVNKAETEG--------LKSQRASLEATIADVKQRGELAIKDAN 182
EN+F+ ++KD+D+AY+ K E + ++ + +A I+ + Q ++ D N
Sbjct: 277 AAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQIHQ----SVTDTN 332
Query: 183 TKLS 186
LS
Sbjct: 333 VILS 336
Score = 102 bits (254), Expect = 4e-22
Identities = 59/130 (45%), Positives = 82/130 (63%), Gaps = 2/130 (1%)
Query: 150 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 209
+ E +K Q +++ IAD +QRGE A+KDA KL+ LE ALQQA +D+A L +YQ+L
Sbjct: 407 QGEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQEL 466
Query: 210 KNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAYADGLS--LAYGGLTSPGL 267
N+KLALD+EIATYRKLLE EE + + + + T+S + ++ A+GG G
Sbjct: 467 MNVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGS 526
Query: 268 SYGLGSSFGS 277
S G G S GS
Sbjct: 527 SSGGGYSSGS 536
>gi|28173564 keratin 73 [Homo sapiens]
Length = 540
Score = 146 bits (369), Expect = 2e-35
Identities = 75/146 (51%), Positives = 110/146 (75%), Gaps = 4/146 (2%)
Query: 11 KRLLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQ 70
K LL+ LN+E+DP IQ V+ QE+E QI+ LNNKFASFI KVRFLEQQN +LETKW LLQ
Sbjct: 111 KSLLAPLNVELDPEIQKVRAQERE--QIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQ 168
Query: 71 QQKM--AWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINK 128
Q + +N+ + + YI+N R Q +TL ++++L++EL +++ +VED+K +Y++EINK
Sbjct: 169 QLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINK 228
Query: 129 CTEMENEFILIRKDMDDAYVNKAETE 154
T ENEF++++KD+D AY +K E +
Sbjct: 229 RTTAENEFVVLKKDVDAAYTSKVELQ 254
Score = 100 bits (248), Expect = 2e-21
Identities = 54/125 (43%), Positives = 77/125 (61%), Gaps = 8/125 (6%)
Query: 150 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 209
++E E +K Q A+LE IAD +QRG+ A+KDA KL +LE ALQQA +++A L EYQ+L
Sbjct: 361 RSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQEL 420
Query: 210 KNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAYADGLSLAYGGLTSPGLSY 269
++KL+LDIEIATYRKLLE EE + T S ++ + G+ G +
Sbjct: 421 LSVKLSLDIEIATYRKLLEGEECRMSG--------EYTNSVSISVINSSMAGMAGTGAGF 472
Query: 270 GLGSS 274
G ++
Sbjct: 473 GFSNA 477
>gi|194018511 keratin 77 [Homo sapiens]
Length = 578
Score = 145 bits (366), Expect = 5e-35
Identities = 76/144 (52%), Positives = 106/144 (73%), Gaps = 4/144 (2%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL L+LEVDP IQ ++ QE+E QI LNNKFASFI KVRFLEQQN +L+TKW LLQQ
Sbjct: 145 LLEPLHLEVDPEIQRIKTQERE--QIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQV 202
Query: 73 KMAW--SNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCT 130
+ +N+ + ++YI + R Q D L E+++ AE+ +MQ +VED+K+KY+DEINK T
Sbjct: 203 NTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRT 262
Query: 131 EMENEFILIRKDMDDAYVNKAETE 154
EN+F++++KD+D AYV+K + E
Sbjct: 263 GSENDFVVLKKDVDAAYVSKVDLE 286
Score = 91.3 bits (225), Expect = 1e-18
Identities = 50/128 (39%), Positives = 79/128 (61%), Gaps = 1/128 (0%)
Query: 150 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 209
+AE +K Q +++ I+D ++RGE A++DA KL LE ALQQ+ +++A L +YQ +
Sbjct: 393 QAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAM 452
Query: 210 KNMKLALDIEIATYRKLLESEESHLESGMQ-NMSIHTKTTSAYADGLSLAYGGLTSPGLS 268
+KL+LD+EIATYR+LLE EES + +Q ++SI + + +G + G S G
Sbjct: 453 LGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSVNGGAGGGGSYGSGGYG 512
Query: 269 YGLGSSFG 276
G G +G
Sbjct: 513 GGSGGGYG 520
>gi|148612803 keratin 6 irs4 [Homo sapiens]
Length = 529
Score = 144 bits (362), Expect = 1e-34
Identities = 84/184 (45%), Positives = 121/184 (65%), Gaps = 7/184 (3%)
Query: 11 KRLLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQ 70
K LL+ LN+E+DP IQ V+ QE+E QI+ LN+KFASFI KVRFLEQQN +LETKW LLQ
Sbjct: 119 KSLLAPLNVELDPEIQKVRAQERE--QIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQ 176
Query: 71 QQKM--AWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINK 128
Q + N+ + + YI+N R Q +TL ++++L++EL +M+ LVED+K +Y+ EIN+
Sbjct: 177 QLDLNNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINR 236
Query: 129 CTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKL 188
T ENEF++++KD D AY K E L+++ SL+ I +K + I T S+
Sbjct: 237 RTTAENEFVVLKKDADAAYAVKVE---LQAKVDSLDKEIKFLKCLYDAEIAQIQTHASET 293
Query: 189 EAAL 192
L
Sbjct: 294 SVIL 297
Score = 105 bits (262), Expect = 5e-23
Identities = 64/144 (44%), Positives = 89/144 (61%), Gaps = 8/144 (5%)
Query: 150 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 209
+ E +K QRASLE IAD +QRG+ A+KDA KL +LE AL QA +++A L EYQ+L
Sbjct: 369 RCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQEL 428
Query: 210 KNMKLALDIEIATYRKLLESEESHLE-SGMQNMSIHTKTTSAYADGLSLAYGGLTSPGLS 268
++KLALD+EIATYRKLLE EE + ++SI ++S+Y +Y +S G+
Sbjct: 429 MSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSY------SYHHPSSAGVD 482
Query: 269 YGLGSSFGSDMGSSSFSCTSSTRA 292
G + GS GS+ T +T A
Sbjct: 483 LGASAVAGSS-GSTQSGQTKTTEA 505
>gi|27477127 keratin 82 [Homo sapiens]
Length = 513
Score = 133 bits (335), Expect = 2e-31
Identities = 66/142 (46%), Positives = 103/142 (72%), Gaps = 2/142 (1%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL L LE+DP +Q V+ EKE QI+ LNN+FASFI KVRFLEQ+N +LETKW+ +QQQ
Sbjct: 101 LLVPLALEIDPTVQRVKRDEKE--QIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQ 158
Query: 73 KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCTEM 132
+ +N+ +F+ YI+ R Q D + ++++LE+EL ++Q +E +K KY++E++ +
Sbjct: 159 RCCQTNIEPIFEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCV 218
Query: 133 ENEFILIRKDMDDAYVNKAETE 154
ENEF+ ++KD+D A++ KA+ E
Sbjct: 219 ENEFVALKKDVDTAFLMKADLE 240
Score = 100 bits (250), Expect = 1e-21
Identities = 60/125 (48%), Positives = 80/125 (64%), Gaps = 3/125 (2%)
Query: 152 ETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKN 211
ETE +K+QR LE IA+ +Q+GE A+ DA KL+ LE ALQ+A QDMA L EYQ++ N
Sbjct: 349 ETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMN 408
Query: 212 MKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAYADGLSLAYGGLTSPGLSYGL 271
KL LDIEIATYR+LLE EE L G+ ++I + S+ G+++P LS G+
Sbjct: 409 SKLGLDIEIATYRRLLEGEEHRLCEGIGPVNI---SVSSSKGAFLYEPCGVSTPVLSTGV 465
Query: 272 GSSFG 276
S G
Sbjct: 466 LRSNG 470
>gi|4504935 keratin 85 [Homo sapiens]
Length = 507
Score = 133 bits (334), Expect = 2e-31
Identities = 67/157 (42%), Positives = 107/157 (68%), Gaps = 8/157 (5%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL+ LNLE+DPN Q V+++EKE QI++LN++FA+FI KVRFLEQQN +LETKW Q Q
Sbjct: 104 LLTPLNLEIDPNAQCVKQEEKE--QIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQ 161
Query: 73 KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCTEM 132
+ SN+ +F YI R + + + + +L +EL ++Q ++E +K KY++E+
Sbjct: 162 RCCESNLEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATA 221
Query: 133 ENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIAD 169
ENEF++++KD+D AY+ K++ E A++EA + +
Sbjct: 222 ENEFVVLKKDVDCAYLRKSDLE------ANVEALVEE 252
Score = 110 bits (274), Expect = 2e-24
Identities = 103/317 (32%), Positives = 154/317 (48%), Gaps = 46/317 (14%)
Query: 12 RLLSLLNLEVDPNIQAVQEQEKEKEQIR-TLNNKFASFIGKVRFLEQQNNMLETKWSLLQ 70
RL S LN V ++ +++ +E+ +R T N+F V + + LE L
Sbjct: 192 RLASELN-HVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALV 250
Query: 71 QQKMAWSNMGNMFKSYINNPRGQ-PDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEIN-- 127
++ S + +++ I + DT V K+ +L NM ++ + K +Y D +
Sbjct: 251 EES---SFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDL-NMDCIIAEIKAQYDDVASRS 306
Query: 128 ----------KCTEMENEFI-----LIRKDMDDAYVNK------AETEGLKSQRASLEAT 166
KC EM+ I L R + +N+ AE E K QRA LEA
Sbjct: 307 RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAA 366
Query: 167 IADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKL 226
+A+ +Q+GE A+ DA KL++LE ALQ+A QDMA L EYQ++ N KL LDIEIATYR+L
Sbjct: 367 VAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRL 426
Query: 227 LESEESHLESGMQNMSIHTKTTSAYADGLSLAYGGLTSPGLSYGLG-SSFGSDM------ 279
LE EE L G+ ++++ ++ L+Y T+PG G S+ G +
Sbjct: 427 LEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYS--TTPGRQITSGPSAIGGSITVVAPD 484
Query: 280 -------GSSSFSCTSS 289
SSSFSC SS
Sbjct: 485 SCAPCQPRSSSFSCGSS 501
>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 486
Score = 129 bits (323), Expect = 4e-30
Identities = 66/158 (41%), Positives = 108/158 (68%), Gaps = 8/158 (5%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL+ LNLE+DPN Q V+++EKE QI++LN++FA+FI KVRFLEQQN +LETK Q +
Sbjct: 87 LLTPLNLEIDPNAQCVKQEEKE--QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR 144
Query: 73 KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCTEM 132
+ SN+ +F+ YI R + + + + +L +EL ++Q ++E +K KY++E++
Sbjct: 145 ECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATA 204
Query: 133 ENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADV 170
ENEF+ ++KD+D AY+ K++ E A++EA I ++
Sbjct: 205 ENEFVALKKDVDCAYLRKSDLE------ANVEALIQEI 236
Score = 104 bits (259), Expect = 1e-22
Identities = 86/260 (33%), Positives = 133/260 (51%), Gaps = 36/260 (13%)
Query: 12 RLLSLLNLEVDPNIQAVQEQEKEKEQIR-TLNNKFASFIGKVRFLEQQNNMLETKWSLLQ 70
RL S LN V ++ +++ +E+ +R T N+F + V + + LE L
Sbjct: 175 RLASELN-HVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALI 233
Query: 71 QQ----KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEI 126
Q+ + + + +S+I+ DT V KL +L NM ++ + K +Y D +
Sbjct: 234 QEIDFLRRLYEEEIRVLQSHIS------DTSVVVKLDNSRDL-NMDCIIAEIKAQYDDIV 286
Query: 127 ------------NKCTEMENEFI-----LIRKDMDDAYVNK------AETEGLKSQRASL 163
+KC EM+ I L R + +N+ AE E K Q + L
Sbjct: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346
Query: 164 EATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATY 223
EA +A +Q+GE A+ DA KL++LE ALQ+A QDMA + EYQ++ N KL LDIEIATY
Sbjct: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406
Query: 224 RKLLESEESHLESGMQNMSI 243
R+LLE EE L G+ ++++
Sbjct: 407 RRLLEGEEQRLCEGVGSVNV 426
>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 486
Score = 129 bits (323), Expect = 4e-30
Identities = 66/158 (41%), Positives = 108/158 (68%), Gaps = 8/158 (5%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL+ LNLE+DPN Q V+++EKE QI++LN++FA+FI KVRFLEQQN +LETK Q +
Sbjct: 87 LLTPLNLEIDPNAQCVKQEEKE--QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR 144
Query: 73 KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCTEM 132
+ SN+ +F+ YI R + + + + +L +EL ++Q ++E +K KY++E++
Sbjct: 145 ECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATA 204
Query: 133 ENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADV 170
ENEF+ ++KD+D AY+ K++ E A++EA I ++
Sbjct: 205 ENEFVALKKDVDCAYLRKSDLE------ANVEALIQEI 236
Score = 104 bits (259), Expect = 1e-22
Identities = 86/260 (33%), Positives = 133/260 (51%), Gaps = 36/260 (13%)
Query: 12 RLLSLLNLEVDPNIQAVQEQEKEKEQIR-TLNNKFASFIGKVRFLEQQNNMLETKWSLLQ 70
RL S LN V ++ +++ +E+ +R T N+F + V + + LE L
Sbjct: 175 RLASELN-HVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALI 233
Query: 71 QQ----KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEI 126
Q+ + + + +S+I+ DT V KL +L NM ++ + K +Y D +
Sbjct: 234 QEIDFLRRLYEEEIRVLQSHIS------DTSVVVKLDNSRDL-NMDCIIAEIKAQYDDIV 286
Query: 127 ------------NKCTEMENEFI-----LIRKDMDDAYVNK------AETEGLKSQRASL 163
+KC EM+ I L R + +N+ AE E K Q + L
Sbjct: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346
Query: 164 EATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATY 223
EA +A +Q+GE A+ DA KL++LE ALQ+A QDMA + EYQ++ N KL LDIEIATY
Sbjct: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406
Query: 224 RKLLESEESHLESGMQNMSI 243
R+LLE EE L G+ ++++
Sbjct: 407 RRLLEGEEQRLCEGVGSVNV 426
>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
sapiens]
Length = 486
Score = 129 bits (323), Expect = 4e-30
Identities = 66/158 (41%), Positives = 108/158 (68%), Gaps = 8/158 (5%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL+ LNLE+DPN Q V+++EKE QI++LN++FA+FI KVRFLEQQN +LETK Q +
Sbjct: 87 LLTPLNLEIDPNAQCVKQEEKE--QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR 144
Query: 73 KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCTEM 132
+ SN+ +F+ YI R + + + + +L +EL ++Q ++E +K KY++E++
Sbjct: 145 ECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATA 204
Query: 133 ENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADV 170
ENEF+ ++KD+D AY+ K++ E A++EA I ++
Sbjct: 205 ENEFVALKKDVDCAYLRKSDLE------ANVEALIQEI 236
Score = 104 bits (259), Expect = 1e-22
Identities = 86/260 (33%), Positives = 133/260 (51%), Gaps = 36/260 (13%)
Query: 12 RLLSLLNLEVDPNIQAVQEQEKEKEQIR-TLNNKFASFIGKVRFLEQQNNMLETKWSLLQ 70
RL S LN V ++ +++ +E+ +R T N+F + V + + LE L
Sbjct: 175 RLASELN-HVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALI 233
Query: 71 QQ----KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEI 126
Q+ + + + +S+I+ DT V KL +L NM ++ + K +Y D +
Sbjct: 234 QEIDFLRRLYEEEIRVLQSHIS------DTSVVVKLDNSRDL-NMDCIIAEIKAQYDDIV 286
Query: 127 ------------NKCTEMENEFI-----LIRKDMDDAYVNK------AETEGLKSQRASL 163
+KC EM+ I L R + +N+ AE E K Q + L
Sbjct: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346
Query: 164 EATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATY 223
EA +A +Q+GE A+ DA KL++LE ALQ+A QDMA + EYQ++ N KL LDIEIATY
Sbjct: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406
Query: 224 RKLLESEESHLESGMQNMSI 243
R+LLE EE L G+ ++++
Sbjct: 407 RRLLEGEEQRLCEGVGSVNV 426
>gi|14318422 keratin 86 [Homo sapiens]
Length = 486
Score = 129 bits (323), Expect = 4e-30
Identities = 66/158 (41%), Positives = 108/158 (68%), Gaps = 8/158 (5%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL+ LNLE+DPN Q V+++EKE QI++LN++FA+FI KVRFLEQQN +LETK Q +
Sbjct: 87 LLTPLNLEIDPNAQCVKQEEKE--QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR 144
Query: 73 KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCTEM 132
+ SN+ +F+ YI R + + + + +L +EL ++Q ++E +K KY++E++
Sbjct: 145 ECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATA 204
Query: 133 ENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADV 170
ENEF+ ++KD+D AY+ K++ E A++EA I ++
Sbjct: 205 ENEFVALKKDVDCAYLRKSDLE------ANVEALIQEI 236
Score = 104 bits (259), Expect = 1e-22
Identities = 86/260 (33%), Positives = 133/260 (51%), Gaps = 36/260 (13%)
Query: 12 RLLSLLNLEVDPNIQAVQEQEKEKEQIR-TLNNKFASFIGKVRFLEQQNNMLETKWSLLQ 70
RL S LN V ++ +++ +E+ +R T N+F + V + + LE L
Sbjct: 175 RLASELN-HVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALI 233
Query: 71 QQ----KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEI 126
Q+ + + + +S+I+ DT V KL +L NM ++ + K +Y D +
Sbjct: 234 QEIDFLRRLYEEEIRVLQSHIS------DTSVVVKLDNSRDL-NMDCIIAEIKAQYDDIV 286
Query: 127 ------------NKCTEMENEFI-----LIRKDMDDAYVNK------AETEGLKSQRASL 163
+KC EM+ I L R + +N+ AE E K Q + L
Sbjct: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346
Query: 164 EATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATY 223
EA +A +Q+GE A+ DA KL++LE ALQ+A QDMA + EYQ++ N KL LDIEIATY
Sbjct: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406
Query: 224 RKLLESEESHLESGMQNMSI 243
R+LLE EE L G+ ++++
Sbjct: 407 RRLLEGEEQRLCEGVGSVNV 426
>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
Length = 505
Score = 129 bits (323), Expect = 4e-30
Identities = 66/158 (41%), Positives = 108/158 (68%), Gaps = 8/158 (5%)
Query: 13 LLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 72
LL+ LNLE+DPN Q V+++EKE QI++LN++FA+FI KVRFLEQQN +LETK Q +
Sbjct: 87 LLTPLNLEIDPNAQCVKQEEKE--QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR 144
Query: 73 KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEINKCTEM 132
+ SN+ +F+ YI R + + + + +L +EL ++Q ++E +K KY++E++
Sbjct: 145 ECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATA 204
Query: 133 ENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADV 170
ENEF+ ++KD+D AY+ K++ E A++EA I ++
Sbjct: 205 ENEFVALKKDVDCAYLRKSDLE------ANVEALIQEI 236
Score = 102 bits (253), Expect = 6e-22
Identities = 86/260 (33%), Positives = 132/260 (50%), Gaps = 36/260 (13%)
Query: 12 RLLSLLNLEVDPNIQAVQEQEKEKEQIR-TLNNKFASFIGKVRFLEQQNNMLETKWSLLQ 70
RL S LN V ++ +++ +E+ +R T N+F + V + + LE L
Sbjct: 175 RLASELN-HVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALI 233
Query: 71 QQ----KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKNKYKDEI 126
Q+ + + + +S+I+ DT V KL +L NM ++ + K +Y D +
Sbjct: 234 QEIDFLRRLYEEEILILQSHIS------DTSVVVKLDNSRDL-NMDCIIAEIKAQYDDIV 286
Query: 127 ------------NKCTEMENEFI-----LIRKDMDDAYVNK------AETEGLKSQRASL 163
+KC EM+ I L R + +N+ AE E K Q + L
Sbjct: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346
Query: 164 EATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATY 223
EA +A +Q+GE A+ DA KL++LE ALQ+A QDMA + EYQ++ N KL LDIEIATY
Sbjct: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406
Query: 224 RKLLESEESHLESGMQNMSI 243
R+LLE EE L G+ +++
Sbjct: 407 RRLLEGEEQRLCEGIGAVNV 426
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.341
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,138,657
Number of Sequences: 37866
Number of extensions: 413096
Number of successful extensions: 2458
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 126
Number of HSP's successfully gapped in prelim test: 237
Number of HSP's that attempted gapping in prelim test: 1771
Number of HSP's gapped (non-prelim): 760
length of query: 315
length of database: 18,247,518
effective HSP length: 102
effective length of query: 213
effective length of database: 14,385,186
effective search space: 3064044618
effective search space used: 3064044618
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.