Search of human proteins with 169168829

Search of human proteins with 169168829

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169168829 PREDICTED: similar to hCG1643231 [Homo sapiens]
         (313 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169168829 PREDICTED: similar to hCG1643231 [Homo sapiens]          612   e-175
gi|169169468 PREDICTED: similar to hCG1643231 [Homo sapiens]          605   e-173
gi|4504919 keratin 8 [Homo sapiens]                                   259   2e-69
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      198   6e-51
gi|119395754 keratin 5 [Homo sapiens]                                 174   9e-44
gi|5031839 keratin 6A [Homo sapiens]                                  170   1e-42
gi|155969697 keratin 6C [Homo sapiens]                                168   5e-42
gi|119703753 keratin 6B [Homo sapiens]                                168   7e-42
gi|32567786 keratin 6L [Homo sapiens]                                 160   1e-39
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    160   1e-39
gi|109148552 keratin 3 [Homo sapiens]                                 159   3e-39
gi|153791158 keratin 75 [Homo sapiens]                                159   4e-39
gi|67782365 keratin 7 [Homo sapiens]                                  157   1e-38
gi|119395750 keratin 1 [Homo sapiens]                                 155   3e-38
gi|109255249 keratin 4 [Homo sapiens]                                 155   4e-38
gi|15618995 keratin 71 [Homo sapiens]                                 155   6e-38
gi|153791670 keratin 76 [Homo sapiens]                                153   2e-37
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       152   3e-37
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      152   3e-37
gi|47132620 keratin 2 [Homo sapiens]                                  152   5e-37
gi|28173564 keratin 73 [Homo sapiens]                                 150   1e-36
gi|194018511 keratin 77 [Homo sapiens]                                150   1e-36
gi|148612803 keratin 6 irs4 [Homo sapiens]                            147   9e-36
gi|4504935 keratin 85 [Homo sapiens]                                  138   7e-33
gi|27477127 keratin 82 [Homo sapiens]                                 137   2e-32
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   134   1e-31
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   134   1e-31
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   134   1e-31
gi|14318422 keratin 86 [Homo sapiens]                                 134   1e-31
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   134   1e-31

>gi|169168829 PREDICTED: similar to hCG1643231 [Homo sapiens]
          Length = 313

 Score =  612 bits (1577), Expect = e-175
 Identities = 313/313 (100%), Positives = 313/313 (100%)

Query: 1   MSIRVTQKSYKRLLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNML 60
           MSIRVTQKSYKRLLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNML
Sbjct: 1   MSIRVTQKSYKRLLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNML 60

Query: 61  ETKWSLLQQQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKY 120
           ETKWSLLQQQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKY
Sbjct: 61  ETKWSLLQQQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKY 120

Query: 121 KDEINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDAN 180
           KDEINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDAN
Sbjct: 121 KDEINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDAN 180

Query: 181 TKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQNMS 240
           TKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQNMS
Sbjct: 181 TKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQNMS 240

Query: 241 IHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVVKKIKTCD 300
           IHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVVKKIKTCD
Sbjct: 241 IHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVVKKIKTCD 300

Query: 301 GKLVSESSDVLPK 313
           GKLVSESSDVLPK
Sbjct: 301 GKLVSESSDVLPK 313


>gi|169169468 PREDICTED: similar to hCG1643231 [Homo sapiens]
          Length = 315

 Score =  605 bits (1560), Expect = e-173
 Identities = 312/315 (99%), Positives = 313/315 (99%), Gaps = 2/315 (0%)

Query: 1   MSIRVTQKSYKRLLSLLNLEVDPNIQAVQEQEKE--QIRTLNNKFASFIGKVRFLEQQNN 58
           MSIRVTQKSYKRLLSLLNLEVDPNIQAVQEQEKE  QIRTLNNKFASFIGKVRFLEQQNN
Sbjct: 1   MSIRVTQKSYKRLLSLLNLEVDPNIQAVQEQEKEKEQIRTLNNKFASFIGKVRFLEQQNN 60

Query: 59  MLETKWSLLQQQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKN 118
           MLETKWSLLQQQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKL+AELGNMQGLVEDFKN
Sbjct: 61  MLETKWSLLQQQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLEAELGNMQGLVEDFKN 120

Query: 119 KYKDEINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKD 178
           KYKDEINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKD
Sbjct: 121 KYKDEINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKD 180

Query: 179 ANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQN 238
           ANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQN
Sbjct: 181 ANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQN 240

Query: 239 MSIHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVVKKIKT 298
           MSIHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVVKKIKT
Sbjct: 241 MSIHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVVKKIKT 300

Query: 299 CDGKLVSESSDVLPK 313
           CDGKLVSESSDVLPK
Sbjct: 301 CDGKLVSESSDVLPK 315


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  259 bits (662), Expect = 2e-69
 Identities = 151/233 (64%), Positives = 172/233 (73%), Gaps = 16/233 (6%)

Query: 81  FKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEMENEFILIRKD 140
           ++   N  R + +++ Q K +   EL ++ G   D   + K EI+   EM      ++  
Sbjct: 267 YEDIANRSRAEAESMYQIKYE---ELQSLAGKHGDDLRRTKTEIS---EMNRNISRLQ-- 318

Query: 141 MDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQ 200
                   AE EGLK QRASLEA IAD +QRGELAIKDAN KLS+LEAALQ+A QDMA Q
Sbjct: 319 --------AEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQ 370

Query: 201 LHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAYADGLSLAYGGL 260
           L EYQ+L N+KLALDIEIATYRKLLE EES LESGMQNMSIHTKTTS YA GLS AYGGL
Sbjct: 371 LREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSGYAGGLSSAYGGL 430

Query: 261 TSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVVKKIKTCDGKLVSESSDVLPK 313
           TSPGLSY LGSSFGS  GSSSFS TSS+RA+VVKKI+T DGKLVSESSDVLPK
Sbjct: 431 TSPGLSYSLGSSFGSGAGSSSFSRTSSSRAVVVKKIETRDGKLVSESSDVLPK 483



 Score =  225 bits (573), Expect = 4e-59
 Identities = 122/178 (68%), Positives = 142/178 (79%), Gaps = 3/178 (1%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQKM 72
           LLS L LEVDPNIQAV+ QEKEQI+TLNNKFASFI KVRFLEQQN MLETKWSLLQQQK 
Sbjct: 72  LLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKT 131

Query: 73  AWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEMEN 132
           A SNM NMF+SYINN R Q +TL QEKLKL+AELGNMQGLVEDFKNKY+DEINK TEMEN
Sbjct: 132 ARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMEN 191

Query: 133 EFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAAL 190
           EF+LI+KD+D+AY+NK E   L+S+   L   I  ++Q  E  I++  +++S     L
Sbjct: 192 EFVLIKKDVDEAYMNKVE---LESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVL 246


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  198 bits (503), Expect = 6e-51
 Identities = 137/364 (37%), Positives = 197/364 (54%), Gaps = 88/364 (24%)

Query: 11  KRLLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 70
           K LL+ LN+E+DP IQ V+ QE+EQI+ LNNKFASFI KVRFLEQQN +LETKW+LLQQ 
Sbjct: 104 KSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQL 163

Query: 71  KM--AWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCT 128
            +     N+  +++ YI+N + Q + L  + ++L +EL NMQ LVED+K +Y+ EIN+ T
Sbjct: 164 DLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRT 223

Query: 129 EMENEFILIRKDMDDAYVNKAE--------TEGLK------------------------- 155
             ENEF++++KD+D AY+NK E        T+ +K                         
Sbjct: 224 AAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLS 283

Query: 156 ---SQRASLEATIADVK-QRGELAIK--------------------------------DA 179
              ++   L++ IA+V+ Q  E+A+K                                DA
Sbjct: 284 MDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKCADLETAIADAEQRGDCALKDA 343

Query: 180 NTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQNM 239
             KL +LE AL QA +++A  L EYQ+L ++KLALD+EIATYRKLLESEE  +       
Sbjct: 344 RAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRM------- 396

Query: 240 SIHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVVKKIKTC 299
                 +  Y + +S++    T+ G     G+ F    G+SS S +  T A  VK   +C
Sbjct: 397 ------SGEYPNSVSISVISSTNAGAG---GAGFSMGFGASS-SYSYKTAAADVKTKGSC 446

Query: 300 DGKL 303
             +L
Sbjct: 447 GSEL 450


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  174 bits (441), Expect = 9e-44
 Identities = 87/142 (61%), Positives = 114/142 (80%), Gaps = 2/142 (1%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ-- 70
           LL+ LNL++DP+IQ V+ +E+EQI+TLNNKFASFI KVRFLEQQN +L+TKW+LLQ+Q  
Sbjct: 149 LLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGT 208

Query: 71  KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEM 130
           K    N+  +F+ YINN R Q D++V E+ +L +EL NMQ LVEDFKNKY+DEINK T  
Sbjct: 209 KTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTA 268

Query: 131 ENEFILIRKDMDDAYVNKAETE 152
           ENEF++++KD+D AY+NK E E
Sbjct: 269 ENEFVMLKKDVDAAYMNKVELE 290



 Score =  121 bits (303), Expect = 9e-28
 Identities = 82/209 (39%), Positives = 111/209 (53%), Gaps = 20/209 (9%)

Query: 81  FKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEMENEFILIRKD 140
           ++   N  R + ++  Q K +   +     G  +D +N  K EI++   M          
Sbjct: 346 YEEIANRSRTEAESWYQTKYEELQQTAGRHG--DDLRNT-KHEISEMNRMIQRL------ 396

Query: 141 MDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQ 200
                  +AE + +K Q A+L+  IAD +QRGELA+KDA  KL++LE ALQ+A QDMA  
Sbjct: 397 -------RAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARL 449

Query: 201 LHEYQKLKNMKLALDIEIATYRKLLESEESHLES---GMQNMSIHTKTTSAYADGLSLAY 257
           L EYQ+L N KLALD+EIATYRKLLE EE  L     G  N+S+ T + S+   G    Y
Sbjct: 450 LREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSS-GYGSGSGY 508

Query: 258 GGLTSPGLSYGLGSSFGSDMGSSSFSCTS 286
           GG    GL  GLG         S +S +S
Sbjct: 509 GGGLGGGLGGGLGGGLAGGSSGSYYSSSS 537


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  170 bits (431), Expect = 1e-42
 Identities = 86/142 (60%), Positives = 111/142 (78%), Gaps = 2/142 (1%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ-- 70
           LL+ LNL++DP IQ V+ +E+EQI+TLNNKFASFI KVRFLEQQN +LETKW+LLQ+Q  
Sbjct: 144 LLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGT 203

Query: 71  KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEM 130
           K    N+  +F+ YINN R Q D++V E+ +L +EL  MQ LVEDFKNKY+DEINK T  
Sbjct: 204 KTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAA 263

Query: 131 ENEFILIRKDMDDAYVNKAETE 152
           ENEF+ ++KD+D AY+NK E +
Sbjct: 264 ENEFVTLKKDVDAAYMNKVELQ 285



 Score =  118 bits (296), Expect = 6e-27
 Identities = 72/151 (47%), Positives = 94/151 (62%), Gaps = 14/151 (9%)

Query: 148 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 207
           ++E + +K Q A+L+A IAD +QRGE+A+KDA  KL  LE ALQ+A QD+A  L EYQ+L
Sbjct: 392 RSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQEL 451

Query: 208 KNMKLALDIEIATYRKLLESEESHLES---GMQNMSIHTKTTSAYADGLSLAYGGLTSPG 264
            N+KLALD+EIATYRKLLE EE  L     G  N+S+   T S+        YGG +  G
Sbjct: 452 MNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSS-------GYGGASGVG 504

Query: 265 LSYGLGS----SFGSDMGSSSFSCTSSTRAM 291
              GLG     S+GS +G      +SS RA+
Sbjct: 505 SGLGLGGGSSYSYGSGLGVGGGFSSSSGRAI 535


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  168 bits (426), Expect = 5e-42
 Identities = 85/142 (59%), Positives = 111/142 (78%), Gaps = 2/142 (1%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ-- 70
           LL+ LNL++DP IQ V+ +E+EQI+TLNNKFASFI KVRFLEQQN +L+TKW+LLQ+Q  
Sbjct: 144 LLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGT 203

Query: 71  KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEM 130
           K    N+  +F+ YINN R Q D++V E+ +L +EL NMQ LVED KNKY+DEINK T  
Sbjct: 204 KTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAA 263

Query: 131 ENEFILIRKDMDDAYVNKAETE 152
           ENEF+ ++KD+D AY+NK E +
Sbjct: 264 ENEFVTLKKDVDAAYMNKVELQ 285



 Score =  119 bits (298), Expect = 3e-27
 Identities = 73/151 (48%), Positives = 94/151 (62%), Gaps = 14/151 (9%)

Query: 148 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 207
           ++E + +K Q ASL+A IAD +QRGE+A+KDA  KL  LE ALQ+A QD+A  L EYQ+L
Sbjct: 392 RSEIDHVKKQCASLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQEL 451

Query: 208 KNMKLALDIEIATYRKLLESEESHLES---GMQNMSIHTKTTSAYADGLSLAYGGLTSPG 264
            N+KLALD+EIATYRKLLE EE  L     G  N+S+   T       +S  YGG +  G
Sbjct: 452 MNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNVSVVQST-------ISSGYGGASGVG 504

Query: 265 LSYGLGS----SFGSDMGSSSFSCTSSTRAM 291
              GLG     S+GS +G      +SS RA+
Sbjct: 505 SGLGLGGGSSYSYGSGLGIGGGFSSSSGRAI 535


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  168 bits (425), Expect = 7e-42
 Identities = 85/142 (59%), Positives = 110/142 (77%), Gaps = 2/142 (1%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ-- 70
           LL+ LNL++DP IQ V+ +E+EQI+TLNNKFASFI KVRFLEQQN +L+TKW+LLQ+Q  
Sbjct: 144 LLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGT 203

Query: 71  KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEM 130
           K    N+  +F+ YINN R Q D +V E+ +L +EL NMQ LVED KNKY+DEINK T  
Sbjct: 204 KTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAA 263

Query: 131 ENEFILIRKDMDDAYVNKAETE 152
           ENEF+ ++KD+D AY+NK E +
Sbjct: 264 ENEFVTLKKDVDAAYMNKVELQ 285



 Score =  118 bits (295), Expect = 8e-27
 Identities = 72/150 (48%), Positives = 93/150 (62%), Gaps = 14/150 (9%)

Query: 148 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 207
           ++E + +K Q A+L+A IAD +QRGE+A+KDA  KL  LE ALQ+A QD+A  L EYQ+L
Sbjct: 392 RSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQEL 451

Query: 208 KNMKLALDIEIATYRKLLESEESHLES---GMQNMSIHTKTTSAYADGLSLAYGGLTSPG 264
            N+KLALD+EIATYRKLLE EE  L     G  N+S+   T S+        YGG +  G
Sbjct: 452 MNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSS-------GYGGASGVG 504

Query: 265 LSYGLGS----SFGSDMGSSSFSCTSSTRA 290
              GLG     S+GS +G      +SS RA
Sbjct: 505 SGLGLGGGSSYSYGSGLGVGGGFSSSSGRA 534


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  160 bits (406), Expect = 1e-39
 Identities = 86/182 (47%), Positives = 124/182 (68%), Gaps = 7/182 (3%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ-- 70
           LL+ L++E+DP IQ V+ QE+EQI+TLNNKFASFI KVRFLEQQN +LETKW+LLQ+Q  
Sbjct: 123 LLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQ 182

Query: 71  --KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCT 128
              +  +N+  +F++Y+ + R   D L  E+ +L +EL N+Q LVEDFKNKY+DEINK T
Sbjct: 183 NLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHT 242

Query: 129 EMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEA 188
             ENEF++++KD+D AY+ + +  G   +  +L   I  ++Q  E+ +    T +S    
Sbjct: 243 AAENEFVVLKKDVDAAYMGRMDLHG---KVGTLTQEIDFLQQLYEMELSQVQTHVSNTNV 299

Query: 189 AL 190
            L
Sbjct: 300 VL 301



 Score =  107 bits (268), Expect = 1e-23
 Identities = 83/251 (33%), Positives = 127/251 (50%), Gaps = 18/251 (7%)

Query: 48  GKVRFLEQQNNMLETKWSLLQQQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELG 107
           GKV  L Q+ + L+  + +   Q     +  N+  S  NN     D+++ E +K + EL 
Sbjct: 267 GKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAE-VKAQYELI 325

Query: 108 NMQGLVED---FKNKYKD-------EINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQ 157
             +   E    ++ KY++         +   + +NE   + + +      + E +  K Q
Sbjct: 326 AQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRL---QGEADAAKKQ 382

Query: 158 RASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIE 217
              L+  IA+ +QRGELA+KDA  KL  L+ AL QA +D+   L +YQ+L N+KLALD+E
Sbjct: 383 CQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVE 442

Query: 218 IATYRKLLESEESHLESGMQNMSIHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDM 277
           IATYRKLLESEES + SG    ++    T    +  ++  GG  S G    LG S G+  
Sbjct: 443 IATYRKLLESEESRM-SGECPSAVSISVT---GNSTTVCGGGAASFGGGISLGGSGGATK 498

Query: 278 GSSSFSCTSST 288
           G  S +   ST
Sbjct: 499 GGFSTNVGYST 509


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  160 bits (405), Expect = 1e-39
 Identities = 78/142 (54%), Positives = 108/142 (76%)

Query: 11  KRLLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 70
           K LL+ LNLE+DPN Q V++ EKEQI+TLNNKFASFI KVRFLEQQN +LETKWS LQ+Q
Sbjct: 144 KSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQEQ 203

Query: 71  KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEM 130
           K   SN+  +F+SYI N R Q + LV ++ +L+AE  ++Q ++E FK KY++E+      
Sbjct: 204 KCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANA 263

Query: 131 ENEFILIRKDMDDAYVNKAETE 152
           ENEF+ ++KD+D A++NK++ E
Sbjct: 264 ENEFVALKKDVDAAFMNKSDLE 285



 Score =  110 bits (275), Expect = 2e-24
 Identities = 68/146 (46%), Positives = 89/146 (60%), Gaps = 13/146 (8%)

Query: 148 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 207
           KAE E  K+QRA LEA +A+ +Q+GE  + DA  KL+ LE ALQQA QDMA QL EYQ+L
Sbjct: 392 KAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQEL 451

Query: 208 KNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTT--------SAYADGLSLAYGG 259
            N KL LDIEIATYR+LLE EES L  G+  ++I   ++             G +L+ GG
Sbjct: 452 MNAKLGLDIEIATYRRLLEGEESRLCEGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRGG 511

Query: 260 LTSPGLS-----YGLGSSFGSDMGSS 280
           +T  G S      G+ +S G  +G +
Sbjct: 512 VTFSGSSSVCATSGVLASCGPSLGGA 537


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  159 bits (402), Expect = 3e-39
 Identities = 81/144 (56%), Positives = 108/144 (75%), Gaps = 4/144 (2%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQKM 72
           LL  LN+E+DP I  V+ QE+EQI+TLNNKFASFI KVRFLEQQN +LETKW+LLQQQ  
Sbjct: 179 LLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGT 238

Query: 73  A----WSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCT 128
           +     +N+  +F+++IN  R   D ++ E+ +L +EL NM+ LVEDFK KY+DEINK T
Sbjct: 239 SSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRT 298

Query: 129 EMENEFILIRKDMDDAYVNKAETE 152
             ENEF+ ++KD+D AY+NK E +
Sbjct: 299 AAENEFVTLKKDVDSAYMNKVELQ 322



 Score =  123 bits (309), Expect = 2e-28
 Identities = 69/138 (50%), Positives = 90/138 (65%), Gaps = 8/138 (5%)

Query: 148 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 207
           +AE EG+K Q A+L+  IA+ +Q GE+A+KDAN KL +L+AALQQA  D+A  L +YQ+L
Sbjct: 429 RAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQEL 488

Query: 208 KNMKLALDIEIATYRKLLESEESHLE----SGMQNMSIHTKTTSAYADGLSLAYGGLTSP 263
            N+KLALD+EIATYRKLLE EE  +     S +    + + TTSA A G    YGG    
Sbjct: 489 MNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGYGG---- 544

Query: 264 GLSYGLGSSFGSDMGSSS 281
           G+  GLG  F +  GS S
Sbjct: 545 GMGGGLGGGFSAGGGSGS 562


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  159 bits (401), Expect = 4e-39
 Identities = 80/142 (56%), Positives = 109/142 (76%), Gaps = 2/142 (1%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ-- 70
           LL+ L+L++DP IQ V+ +E+EQI+TLNNKFASFI KVRFLEQQN +LETKW+LLQ+Q  
Sbjct: 130 LLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGS 189

Query: 71  KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEM 130
           +    N+  +F SY +  R Q +++  E+ +L+AEL NMQ +VEDFK +Y+DEINK T  
Sbjct: 190 RTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAA 249

Query: 131 ENEFILIRKDMDDAYVNKAETE 152
           ENEF+ ++KD+D AY+NK E E
Sbjct: 250 ENEFVALKKDVDAAYMNKVELE 271



 Score =  123 bits (308), Expect = 2e-28
 Identities = 88/219 (40%), Positives = 116/219 (52%), Gaps = 31/219 (14%)

Query: 81  FKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEMENEFILIRKD 140
           ++   N  R + ++  Q K +         G  +D +N  K EI++   M          
Sbjct: 327 YEDIANRSRAEAESWYQTKYEELQVTAGRHG--DDLRNT-KQEISEMNRMIQRL------ 377

Query: 141 MDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQ 200
                  +AE + +K Q +SL+  IAD +QRGELA+KDA  KL  LE ALQ+A QDMA  
Sbjct: 378 -------RAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARL 430

Query: 201 LHEYQKLKNMKLALDIEIATYRKLLESEESHLES---GMQNMSIHTKT-TSAYADGLSLA 256
           L EYQ+L N+KLALD+EIATYRKLLE EE  L        N+S+ T T +S Y  G S+ 
Sbjct: 431 LREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYGSGSSIG 490

Query: 257 YGGLTSPGLSYGLGSSF--------GSDMGSSSFSCTSS 287
            G L   GL  G G SF        G+ +G S FS TS+
Sbjct: 491 GGNL---GLGGGSGYSFTTSGGHSLGAGLGGSGFSATSN 526


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  157 bits (397), Expect = 1e-38
 Identities = 80/141 (56%), Positives = 111/141 (78%), Gaps = 1/141 (0%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQKM 72
           LL+ L L+ DP++Q V+++E EQI+TLNNKFASFI KVRFLEQQN +LETKW+LLQ+QK 
Sbjct: 72  LLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKS 131

Query: 73  AWSN-MGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEME 131
           A S+ + ++F++ I   RGQ + L  +  +L+AEL +MQ +VEDFKNKY+DEIN  T  E
Sbjct: 132 AKSSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAE 191

Query: 132 NEFILIRKDMDDAYVNKAETE 152
           NEF++++KD+D AY++K E E
Sbjct: 192 NEFVVLKKDVDAAYMSKVELE 212



 Score =  122 bits (306), Expect = 4e-28
 Identities = 74/150 (49%), Positives = 97/150 (64%), Gaps = 18/150 (12%)

Query: 148 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 207
           +AE + +K+QRA LEA IA+ ++RGELA+KDA  K  +LEAALQ+  QDMA QL EYQ+L
Sbjct: 319 QAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQEL 378

Query: 208 KNMKLALDIEIATYRKLLESEESHLES---GMQNMSIHTKTTSAYADGLSLAYGGLTSPG 264
            ++KLALDIEIATYRKLLE EES L     G  N+S+   T            GG +S G
Sbjct: 379 MSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNST------------GGSSSGG 426

Query: 265 LSYGLGSSFGSDMGSSSFSCTSSTRAMVVK 294
              G+G + G  MGS++ S +SS    ++K
Sbjct: 427 ---GIGLTLGGTMGSNALSFSSSAGPGLLK 453


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  155 bits (393), Expect = 3e-38
 Identities = 96/236 (40%), Positives = 138/236 (58%), Gaps = 31/236 (13%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQ--Q 70
           LL  LN+E+DP IQ V+ +E+EQI++LNN+FASFI KVRFLEQQN +L+TKW LLQQ   
Sbjct: 161 LLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDT 220

Query: 71  KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEM 130
                N+   F+S+INN R + D L  ++ +L +EL NMQ +VED++NKY+DEINK T  
Sbjct: 221 STRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNA 280

Query: 131 ENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAAL 190
           ENEF+ I+KD+D AY+ K +          L+A + +++Q           ++  L A  
Sbjct: 281 ENEFVTIKKDVDGAYMTKVD----------LQAKLDNLQQ-----------EIDFLTALY 319

Query: 191 QQAMQDMAWQLHEYQKL----KNMKLALDIEI----ATYRKLLESEESHLESGMQN 238
           Q  +  M  Q+ E   +     N  L LD  I    A Y  + +  ++  ES  Q+
Sbjct: 320 QAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQS 375



 Score =  103 bits (258), Expect = 2e-22
 Identities = 63/134 (47%), Positives = 85/134 (63%), Gaps = 6/134 (4%)

Query: 148 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 207
           ++E + +K Q ++L+ +I+D +QRGE A+KDA  KL+ LE ALQQA +D+A  L +YQ+L
Sbjct: 409 RSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQEL 468

Query: 208 KNMKLALDIEIATYRKLLESEESHLESG-MQNMSIHTKTTSAYADGLSLAYGGLTSPGLS 266
            N KLALD+EIATYR LLE EES +      N+S+   T+     G     GG    G  
Sbjct: 469 MNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGG----GGG 524

Query: 267 YGL-GSSFGSDMGS 279
           YG  GSS+GS  GS
Sbjct: 525 YGSGGSSYGSGGGS 538


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  155 bits (392), Expect = 4e-38
 Identities = 79/142 (55%), Positives = 109/142 (76%), Gaps = 2/142 (1%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQKM 72
           LL+ L++E+DP IQ V+ +E+EQI+ LNNKFASFI KV+FLEQQN +LETKW+LLQQQ  
Sbjct: 192 LLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTT 251

Query: 73  AWS--NMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEM 130
             S  N+  +F++Y++  R Q DTL  +K +L++EL  MQ  VEDFK KY++EINK T  
Sbjct: 252 TTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAA 311

Query: 131 ENEFILIRKDMDDAYVNKAETE 152
           EN+F++++KD+D AY+NK E E
Sbjct: 312 ENDFVVLKKDVDAAYLNKVELE 333



 Score =  115 bits (289), Expect = 4e-26
 Identities = 69/144 (47%), Positives = 95/144 (65%), Gaps = 2/144 (1%)

Query: 148 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 207
           +AE E +K Q  +L+ ++AD +QRGE A+KDA++K  +LEAALQQA +++A  L EYQ+L
Sbjct: 440 RAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQEL 499

Query: 208 KNMKLALDIEIATYRKLLESEESHLESGMQN-MSIHTKTTSAYADGLSLAYGGLTSPGLS 266
            ++KLALDIEIATYRKLLE EE  +    Q+ +SI   + S    G+S   G  +  GLS
Sbjct: 500 MSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLS 559

Query: 267 YGLGSSFGSDMG-SSSFSCTSSTR 289
            G GS  GS  G   S S +SS++
Sbjct: 560 SGFGSGSGSGFGFGGSVSGSSSSK 583


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  155 bits (391), Expect = 6e-38
 Identities = 82/167 (49%), Positives = 116/167 (69%), Gaps = 10/167 (5%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQKM 72
           LL+ LN+E+DP IQ V+ QE+EQI+ LNNKFASFI KVRFLEQQN +LETKW LLQQ  +
Sbjct: 111 LLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDL 170

Query: 73  --AWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEM 130
               +N+  + + YI+N R Q +TL  ++++L +EL N++ +VED+K +Y++EINK T  
Sbjct: 171 NNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAA 230

Query: 131 ENEFILIRKDMDDAYVNKAETEG--------LKSQRASLEATIADVK 169
           ENEF+L++KD+D AY NK E +         +K  R   EA I  ++
Sbjct: 231 ENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQ 277



 Score =  101 bits (251), Expect = 1e-21
 Identities = 69/196 (35%), Positives = 103/196 (52%), Gaps = 31/196 (15%)

Query: 114 EDFKNKYKDEINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGE 173
           +D KN  K+EI++ T +                 ++E E +K Q ++LE  IAD +QRG+
Sbjct: 339 DDLKNT-KNEISELTRLIQRI-------------RSEIENVKKQASNLETAIADAEQRGD 384

Query: 174 LAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLE 233
            A+KDA  KL +LE AL QA +++A  L EYQ+L ++KLALD+EIATYRKLLESEE  + 
Sbjct: 385 NALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRM- 443

Query: 234 SGMQNMSIHTKTTSAYADGLSLAYGGLTSPGLSYGLGSSFGSDMGSSSFSCTSSTRAMVV 293
                       +  +   +S++    TS G  YG    F   M S  +   SS     V
Sbjct: 444 ------------SGEFPSPVSISIISSTSGGSVYG----FRPSMVSGGYVANSSNCISGV 487

Query: 294 KKIKTCDGKLVSESSD 309
             ++  +G+    ++D
Sbjct: 488 CSVRGGEGRSRGSAND 503


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  153 bits (387), Expect = 2e-37
 Identities = 88/180 (48%), Positives = 120/180 (66%), Gaps = 5/180 (2%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQKM 72
           LL  LN+E+DP I  V+ QE+EQI+TLNNKFASFI KVRFLEQQN +LETKW LLQQQ  
Sbjct: 164 LLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTT 223

Query: 73  AW--SNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEM 130
               S++   F+SYI+    Q D+L+ E+  L+ EL +MQ LVEDFK KY+DEINK T  
Sbjct: 224 GSGPSSLEPCFESYISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAA 283

Query: 131 ENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAAL 190
           ENEF+ ++KD+D A++NK E   L+++  SL   ++ ++   E+ +    +  S     L
Sbjct: 284 ENEFVGLKKDVDAAFMNKVE---LQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVL 340



 Score =  108 bits (269), Expect = 8e-24
 Identities = 81/232 (34%), Positives = 113/232 (48%), Gaps = 29/232 (12%)

Query: 53  LEQQNNMLETKWSLLQQQKMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGL 112
           L   NN      S++ + +  +  +    KS       + + L Q KL    EL    G 
Sbjct: 340 LSMDNNRCLDLGSIIAEVRAQYEEIAQRSKS-------EAEALYQTKL---GELQTTAGR 389

Query: 113 VEDFKNKYKDEINKCTEMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRG 172
             D     K EI +   M                 +AE E +K Q A+L+  IA+ +QRG
Sbjct: 390 HGDDLRNTKSEIMELNRMIQRL-------------RAEIENVKKQNANLQTAIAEAEQRG 436

Query: 173 ELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHL 232
           E+A+KDAN KL  L+ ALQ+A  D+A  L +YQ+L N+KLALD+EIATYRKLLE EE  +
Sbjct: 437 EMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRM 496

Query: 233 ESGMQN---MSIHTKTTSAYADGLSL--AYGGLTSPGL-SYGLGSSFGSDMG 278
               Q+   +S+ +  TS      S    +GG++  G   Y  GSS  S  G
Sbjct: 497 SGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSG 548


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  152 bits (385), Expect = 3e-37
 Identities = 103/289 (35%), Positives = 153/289 (52%), Gaps = 46/289 (15%)

Query: 11  KRLLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 70
           K LL+ LN+E+DP IQ V+ QE+EQI+ LNNKFASFI KVRFLEQQN +LETKW+LLQQ 
Sbjct: 104 KSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQL 163

Query: 71  KM--AWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCT 128
            +     N+  +++ YI+N + Q + L  + ++L +EL NMQ LVED+K +Y+ EIN+ T
Sbjct: 164 DLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRT 223

Query: 129 EMENEFILIRKDMDDAYVNKAE--------TEGLK------------------------- 155
             ENEF++++KD+D AY+NK E        T+ +K                         
Sbjct: 224 AAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLS 283

Query: 156 ---SQRASLEATIADVK-QRGELAIKDA-------NTKLSKLEAALQQAMQDMAWQLHEY 204
              ++   L++ IA+V+ Q  E+A+K          TK+ +L+    Q   D+     E 
Sbjct: 284 MDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEI 343

Query: 205 QKLKNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAYADGL 253
            +L  +   +  EI   +K     E+ +    Q      K   A  D L
Sbjct: 344 SELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDEL 392



 Score =  101 bits (251), Expect = 1e-21
 Identities = 64/156 (41%), Positives = 90/156 (57%), Gaps = 17/156 (10%)

Query: 148 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 207
           ++E   +K Q A LE  IAD +QRG+ A+KDA  KL +LE AL QA +++A  L EYQ+L
Sbjct: 354 RSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQEL 413

Query: 208 KNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAYADGLSLAYGGLTSPGLSY 267
            ++KLALD+EIATYRKLLESEE  +             +  Y + +S++    T+ G   
Sbjct: 414 VSLKLALDMEIATYRKLLESEECRM-------------SGEYPNSVSISVISSTNAGAG- 459

Query: 268 GLGSSFGSDMGSSSFSCTSSTRAMVVKKIKTCDGKL 303
             G+ F    G+SS S +  T A  VK   +C  +L
Sbjct: 460 --GAGFSMGFGASS-SYSYKTAAADVKTKGSCGSEL 492


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  152 bits (385), Expect = 3e-37
 Identities = 103/289 (35%), Positives = 153/289 (52%), Gaps = 46/289 (15%)

Query: 11  KRLLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 70
           K LL+ LN+E+DP IQ V+ QE+EQI+ LNNKFASFI KVRFLEQQN +LETKW+LLQQ 
Sbjct: 104 KSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQL 163

Query: 71  KM--AWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCT 128
            +     N+  +++ YI+N + Q + L  + ++L +EL NMQ LVED+K +Y+ EIN+ T
Sbjct: 164 DLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRT 223

Query: 129 EMENEFILIRKDMDDAYVNKAE--------TEGLK------------------------- 155
             ENEF++++KD+D AY+NK E        T+ +K                         
Sbjct: 224 AAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLS 283

Query: 156 ---SQRASLEATIADVK-QRGELAIKDA-------NTKLSKLEAALQQAMQDMAWQLHEY 204
              ++   L++ IA+V+ Q  E+A+K          TK+ +L+    Q   D+     E 
Sbjct: 284 MDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEI 343

Query: 205 QKLKNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAYADGL 253
            +L  +   +  EI   +K     E+ +    Q      K   A  D L
Sbjct: 344 SELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDEL 392



 Score =  101 bits (251), Expect = 1e-21
 Identities = 64/156 (41%), Positives = 90/156 (57%), Gaps = 17/156 (10%)

Query: 148 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 207
           ++E   +K Q A LE  IAD +QRG+ A+KDA  KL +LE AL QA +++A  L EYQ+L
Sbjct: 354 RSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQEL 413

Query: 208 KNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAYADGLSLAYGGLTSPGLSY 267
            ++KLALD+EIATYRKLLESEE  +             +  Y + +S++    T+ G   
Sbjct: 414 VSLKLALDMEIATYRKLLESEECRM-------------SGEYPNSVSISVISSTNAGAG- 459

Query: 268 GLGSSFGSDMGSSSFSCTSSTRAMVVKKIKTCDGKL 303
             G+ F    G+SS S +  T A  VK   +C  +L
Sbjct: 460 --GAGFSMGFGASS-SYSYKTAAADVKTKGSCGSEL 492


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  152 bits (383), Expect = 5e-37
 Identities = 84/182 (46%), Positives = 118/182 (64%), Gaps = 14/182 (7%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQKM 72
           LL  LN++VDP IQ V+ QE+EQI+TLNNKFASFI KVRFLEQQN +L+TKW LLQQ  +
Sbjct: 159 LLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNV 218

Query: 73  AWS--NMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEM 130
                N+  +F+ YI++ +   D L  E+    +EL NMQ LVED+K KY+DEINK T  
Sbjct: 219 GTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAA 278

Query: 131 ENEFILIRKDMDDAYVNKAETEG--------LKSQRASLEATIADVKQRGELAIKDANTK 182
           EN+F+ ++KD+D+AY+ K E +         ++  +   +A I+ + Q    ++ D N  
Sbjct: 279 ENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQIHQ----SVTDTNVI 334

Query: 183 LS 184
           LS
Sbjct: 335 LS 336



 Score =  102 bits (254), Expect = 4e-22
 Identities = 59/130 (45%), Positives = 82/130 (63%), Gaps = 2/130 (1%)

Query: 148 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 207
           + E   +K Q  +++  IAD +QRGE A+KDA  KL+ LE ALQQA +D+A  L +YQ+L
Sbjct: 407 QGEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQEL 466

Query: 208 KNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAYADGLS--LAYGGLTSPGL 265
            N+KLALD+EIATYRKLLE EE  +   + +    + T+S  +  ++   A+GG    G 
Sbjct: 467 MNVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGS 526

Query: 266 SYGLGSSFGS 275
           S G G S GS
Sbjct: 527 SSGGGYSSGS 536


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score =  150 bits (379), Expect = 1e-36
 Identities = 75/144 (52%), Positives = 109/144 (75%), Gaps = 2/144 (1%)

Query: 11  KRLLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 70
           K LL+ LN+E+DP IQ V+ QE+EQI+ LNNKFASFI KVRFLEQQN +LETKW LLQQ 
Sbjct: 111 KSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQL 170

Query: 71  KM--AWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCT 128
            +    +N+  + + YI+N R Q +TL  ++++L +EL +++ +VED+K +Y++EINK T
Sbjct: 171 DLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRT 230

Query: 129 EMENEFILIRKDMDDAYVNKAETE 152
             ENEF++++KD+D AY +K E +
Sbjct: 231 TAENEFVVLKKDVDAAYTSKVELQ 254



 Score =  100 bits (248), Expect = 2e-21
 Identities = 54/125 (43%), Positives = 77/125 (61%), Gaps = 8/125 (6%)

Query: 148 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 207
           ++E E +K Q A+LE  IAD +QRG+ A+KDA  KL +LE ALQQA +++A  L EYQ+L
Sbjct: 361 RSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQEL 420

Query: 208 KNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAYADGLSLAYGGLTSPGLSY 267
            ++KL+LDIEIATYRKLLE EE  +            T S     ++ +  G+   G  +
Sbjct: 421 LSVKLSLDIEIATYRKLLEGEECRMSG--------EYTNSVSISVINSSMAGMAGTGAGF 472

Query: 268 GLGSS 272
           G  ++
Sbjct: 473 GFSNA 477


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  150 bits (379), Expect = 1e-36
 Identities = 76/142 (53%), Positives = 105/142 (73%), Gaps = 2/142 (1%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQ--Q 70
           LL  L+LEVDP IQ ++ QE+EQI  LNNKFASFI KVRFLEQQN +L+TKW LLQQ   
Sbjct: 145 LLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNT 204

Query: 71  KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEM 130
               +N+  + ++YI + R Q D L  E+++  AE+ +MQ +VED+K+KY+DEINK T  
Sbjct: 205 STGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGS 264

Query: 131 ENEFILIRKDMDDAYVNKAETE 152
           EN+F++++KD+D AYV+K + E
Sbjct: 265 ENDFVVLKKDVDAAYVSKVDLE 286



 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 50/128 (39%), Positives = 79/128 (61%), Gaps = 1/128 (0%)

Query: 148 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 207
           +AE   +K Q   +++ I+D ++RGE A++DA  KL  LE ALQQ+ +++A  L +YQ +
Sbjct: 393 QAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAM 452

Query: 208 KNMKLALDIEIATYRKLLESEESHLESGMQ-NMSIHTKTTSAYADGLSLAYGGLTSPGLS 266
             +KL+LD+EIATYR+LLE EES +   +Q ++SI  + +    +G +   G   S G  
Sbjct: 453 LGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSVNGGAGGGGSYGSGGYG 512

Query: 267 YGLGSSFG 274
            G G  +G
Sbjct: 513 GGSGGGYG 520


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  147 bits (372), Expect = 9e-36
 Identities = 84/182 (46%), Positives = 120/182 (65%), Gaps = 5/182 (2%)

Query: 11  KRLLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQ 70
           K LL+ LN+E+DP IQ V+ QE+EQI+ LN+KFASFI KVRFLEQQN +LETKW LLQQ 
Sbjct: 119 KSLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQL 178

Query: 71  KM--AWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCT 128
            +     N+  + + YI+N R Q +TL  ++++L +EL +M+ LVED+K +Y+ EIN+ T
Sbjct: 179 DLNNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRT 238

Query: 129 EMENEFILIRKDMDDAYVNKAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEA 188
             ENEF++++KD D AY  K E   L+++  SL+  I  +K   +  I    T  S+   
Sbjct: 239 TAENEFVVLKKDADAAYAVKVE---LQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSV 295

Query: 189 AL 190
            L
Sbjct: 296 IL 297



 Score =  105 bits (262), Expect = 5e-23
 Identities = 64/144 (44%), Positives = 89/144 (61%), Gaps = 8/144 (5%)

Query: 148 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 207
           + E   +K QRASLE  IAD +QRG+ A+KDA  KL +LE AL QA +++A  L EYQ+L
Sbjct: 369 RCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQEL 428

Query: 208 KNMKLALDIEIATYRKLLESEESHLE-SGMQNMSIHTKTTSAYADGLSLAYGGLTSPGLS 266
            ++KLALD+EIATYRKLLE EE  +      ++SI   ++S+Y      +Y   +S G+ 
Sbjct: 429 MSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSY------SYHHPSSAGVD 482

Query: 267 YGLGSSFGSDMGSSSFSCTSSTRA 290
            G  +  GS  GS+    T +T A
Sbjct: 483 LGASAVAGSS-GSTQSGQTKTTEA 505


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  138 bits (347), Expect = 7e-33
 Identities = 67/155 (43%), Positives = 107/155 (69%), Gaps = 6/155 (3%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQKM 72
           LL+ LNLE+DPN Q V+++EKEQI++LN++FA+FI KVRFLEQQN +LETKW   Q Q+ 
Sbjct: 104 LLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRC 163

Query: 73  AWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEMEN 132
             SN+  +F  YI   R + + +  +  +L +EL ++Q ++E +K KY++E+      EN
Sbjct: 164 CESNLEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAEN 223

Query: 133 EFILIRKDMDDAYVNKAETEGLKSQRASLEATIAD 167
           EF++++KD+D AY+ K++ E      A++EA + +
Sbjct: 224 EFVVLKKDVDCAYLRKSDLE------ANVEALVEE 252



 Score =  109 bits (273), Expect = 3e-24
 Identities = 86/232 (37%), Positives = 119/232 (51%), Gaps = 40/232 (17%)

Query: 93  DTLVQEKLKLKAELGNMQGLVEDFKNKYKDEIN------------KCTEMENEFI----- 135
           DT V  K+    +L NM  ++ + K +Y D  +            KC EM+   I     
Sbjct: 273 DTSVIVKMDNSRDL-NMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGET 331

Query: 136 LIRKDMDDAYVNK------AETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAA 189
           L R   +   +N+      AE E  K QRA LEA +A+ +Q+GE A+ DA  KL++LE A
Sbjct: 332 LRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGA 391

Query: 190 LQQAMQDMAWQLHEYQKLKNMKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAY 249
           LQ+A QDMA  L EYQ++ N KL LDIEIATYR+LLE EE  L  G+ ++++   ++   
Sbjct: 392 LQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCEGVGSVNVCVSSSRGG 451

Query: 250 ADGLSLAYGGLTSPGLSYGLG-SSFGSDM-------------GSSSFSCTSS 287
                L+Y   T+PG     G S+ G  +              SSSFSC SS
Sbjct: 452 VSCGGLSYS--TTPGRQITSGPSAIGGSITVVAPDSCAPCQPRSSSFSCGSS 501


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  137 bits (344), Expect = 2e-32
 Identities = 65/140 (46%), Positives = 103/140 (73%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQKM 72
           LL  L LE+DP +Q V+  EKEQI+ LNN+FASFI KVRFLEQ+N +LETKW+ +QQQ+ 
Sbjct: 101 LLVPLALEIDPTVQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRC 160

Query: 73  AWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEMEN 132
             +N+  +F+ YI+  R Q D +  ++++L++EL ++Q  +E +K KY++E++    +EN
Sbjct: 161 CQTNIEPIFEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVEN 220

Query: 133 EFILIRKDMDDAYVNKAETE 152
           EF+ ++KD+D A++ KA+ E
Sbjct: 221 EFVALKKDVDTAFLMKADLE 240



 Score =  100 bits (250), Expect = 1e-21
 Identities = 60/125 (48%), Positives = 80/125 (64%), Gaps = 3/125 (2%)

Query: 150 ETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKN 209
           ETE +K+QR  LE  IA+ +Q+GE A+ DA  KL+ LE ALQ+A QDMA  L EYQ++ N
Sbjct: 349 ETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMN 408

Query: 210 MKLALDIEIATYRKLLESEESHLESGMQNMSIHTKTTSAYADGLSLAYGGLTSPGLSYGL 269
            KL LDIEIATYR+LLE EE  L  G+  ++I   + S+          G+++P LS G+
Sbjct: 409 SKLGLDIEIATYRRLLEGEEHRLCEGIGPVNI---SVSSSKGAFLYEPCGVSTPVLSTGV 465

Query: 270 GSSFG 274
             S G
Sbjct: 466 LRSNG 470


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  134 bits (336), Expect = 1e-31
 Identities = 66/156 (42%), Positives = 108/156 (69%), Gaps = 6/156 (3%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQKM 72
           LL+ LNLE+DPN Q V+++EKEQI++LN++FA+FI KVRFLEQQN +LETK    Q ++ 
Sbjct: 87  LLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC 146

Query: 73  AWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEMEN 132
             SN+  +F+ YI   R + + +  +  +L +EL ++Q ++E +K KY++E++     EN
Sbjct: 147 CQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAEN 206

Query: 133 EFILIRKDMDDAYVNKAETEGLKSQRASLEATIADV 168
           EF+ ++KD+D AY+ K++ E      A++EA I ++
Sbjct: 207 EFVALKKDVDCAYLRKSDLE------ANVEALIQEI 236



 Score =  103 bits (256), Expect = 3e-22
 Identities = 87/259 (33%), Positives = 128/259 (49%), Gaps = 36/259 (13%)

Query: 12  RLLSLLN--LEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQ 69
           RL S LN   EV    +   E+E     T  N+F +    V     + + LE     L Q
Sbjct: 175 RLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQ 234

Query: 70  Q----KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEI- 124
           +    +  +     + +S+I+      DT V  KL    +L NM  ++ + K +Y D + 
Sbjct: 235 EIDFLRRLYEEEIRVLQSHIS------DTSVVVKLDNSRDL-NMDCIIAEIKAQYDDIVT 287

Query: 125 -----------NKCTEMENEFI-----LIRKDMDDAYVNK------AETEGLKSQRASLE 162
                      +KC EM+   I     L R   +   +N+      AE E  K Q + LE
Sbjct: 288 RSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLE 347

Query: 163 ATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYR 222
           A +A  +Q+GE A+ DA  KL++LE ALQ+A QDMA  + EYQ++ N KL LDIEIATYR
Sbjct: 348 AAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYR 407

Query: 223 KLLESEESHLESGMQNMSI 241
           +LLE EE  L  G+ ++++
Sbjct: 408 RLLEGEEQRLCEGVGSVNV 426


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  134 bits (336), Expect = 1e-31
 Identities = 66/156 (42%), Positives = 108/156 (69%), Gaps = 6/156 (3%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQKM 72
           LL+ LNLE+DPN Q V+++EKEQI++LN++FA+FI KVRFLEQQN +LETK    Q ++ 
Sbjct: 87  LLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC 146

Query: 73  AWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEMEN 132
             SN+  +F+ YI   R + + +  +  +L +EL ++Q ++E +K KY++E++     EN
Sbjct: 147 CQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAEN 206

Query: 133 EFILIRKDMDDAYVNKAETEGLKSQRASLEATIADV 168
           EF+ ++KD+D AY+ K++ E      A++EA I ++
Sbjct: 207 EFVALKKDVDCAYLRKSDLE------ANVEALIQEI 236



 Score =  103 bits (256), Expect = 3e-22
 Identities = 87/259 (33%), Positives = 128/259 (49%), Gaps = 36/259 (13%)

Query: 12  RLLSLLN--LEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQ 69
           RL S LN   EV    +   E+E     T  N+F +    V     + + LE     L Q
Sbjct: 175 RLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQ 234

Query: 70  Q----KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEI- 124
           +    +  +     + +S+I+      DT V  KL    +L NM  ++ + K +Y D + 
Sbjct: 235 EIDFLRRLYEEEIRVLQSHIS------DTSVVVKLDNSRDL-NMDCIIAEIKAQYDDIVT 287

Query: 125 -----------NKCTEMENEFI-----LIRKDMDDAYVNK------AETEGLKSQRASLE 162
                      +KC EM+   I     L R   +   +N+      AE E  K Q + LE
Sbjct: 288 RSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLE 347

Query: 163 ATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYR 222
           A +A  +Q+GE A+ DA  KL++LE ALQ+A QDMA  + EYQ++ N KL LDIEIATYR
Sbjct: 348 AAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYR 407

Query: 223 KLLESEESHLESGMQNMSI 241
           +LLE EE  L  G+ ++++
Sbjct: 408 RLLEGEEQRLCEGVGSVNV 426


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  134 bits (336), Expect = 1e-31
 Identities = 66/156 (42%), Positives = 108/156 (69%), Gaps = 6/156 (3%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQKM 72
           LL+ LNLE+DPN Q V+++EKEQI++LN++FA+FI KVRFLEQQN +LETK    Q ++ 
Sbjct: 87  LLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC 146

Query: 73  AWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEMEN 132
             SN+  +F+ YI   R + + +  +  +L +EL ++Q ++E +K KY++E++     EN
Sbjct: 147 CQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAEN 206

Query: 133 EFILIRKDMDDAYVNKAETEGLKSQRASLEATIADV 168
           EF+ ++KD+D AY+ K++ E      A++EA I ++
Sbjct: 207 EFVALKKDVDCAYLRKSDLE------ANVEALIQEI 236



 Score =  103 bits (256), Expect = 3e-22
 Identities = 87/259 (33%), Positives = 128/259 (49%), Gaps = 36/259 (13%)

Query: 12  RLLSLLN--LEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQ 69
           RL S LN   EV    +   E+E     T  N+F +    V     + + LE     L Q
Sbjct: 175 RLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQ 234

Query: 70  Q----KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEI- 124
           +    +  +     + +S+I+      DT V  KL    +L NM  ++ + K +Y D + 
Sbjct: 235 EIDFLRRLYEEEIRVLQSHIS------DTSVVVKLDNSRDL-NMDCIIAEIKAQYDDIVT 287

Query: 125 -----------NKCTEMENEFI-----LIRKDMDDAYVNK------AETEGLKSQRASLE 162
                      +KC EM+   I     L R   +   +N+      AE E  K Q + LE
Sbjct: 288 RSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLE 347

Query: 163 ATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYR 222
           A +A  +Q+GE A+ DA  KL++LE ALQ+A QDMA  + EYQ++ N KL LDIEIATYR
Sbjct: 348 AAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYR 407

Query: 223 KLLESEESHLESGMQNMSI 241
           +LLE EE  L  G+ ++++
Sbjct: 408 RLLEGEEQRLCEGVGSVNV 426


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  134 bits (336), Expect = 1e-31
 Identities = 66/156 (42%), Positives = 108/156 (69%), Gaps = 6/156 (3%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQKM 72
           LL+ LNLE+DPN Q V+++EKEQI++LN++FA+FI KVRFLEQQN +LETK    Q ++ 
Sbjct: 87  LLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC 146

Query: 73  AWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEMEN 132
             SN+  +F+ YI   R + + +  +  +L +EL ++Q ++E +K KY++E++     EN
Sbjct: 147 CQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAEN 206

Query: 133 EFILIRKDMDDAYVNKAETEGLKSQRASLEATIADV 168
           EF+ ++KD+D AY+ K++ E      A++EA I ++
Sbjct: 207 EFVALKKDVDCAYLRKSDLE------ANVEALIQEI 236



 Score =  103 bits (256), Expect = 3e-22
 Identities = 87/259 (33%), Positives = 128/259 (49%), Gaps = 36/259 (13%)

Query: 12  RLLSLLN--LEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQ 69
           RL S LN   EV    +   E+E     T  N+F +    V     + + LE     L Q
Sbjct: 175 RLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQ 234

Query: 70  Q----KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEI- 124
           +    +  +     + +S+I+      DT V  KL    +L NM  ++ + K +Y D + 
Sbjct: 235 EIDFLRRLYEEEIRVLQSHIS------DTSVVVKLDNSRDL-NMDCIIAEIKAQYDDIVT 287

Query: 125 -----------NKCTEMENEFI-----LIRKDMDDAYVNK------AETEGLKSQRASLE 162
                      +KC EM+   I     L R   +   +N+      AE E  K Q + LE
Sbjct: 288 RSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLE 347

Query: 163 ATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYR 222
           A +A  +Q+GE A+ DA  KL++LE ALQ+A QDMA  + EYQ++ N KL LDIEIATYR
Sbjct: 348 AAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYR 407

Query: 223 KLLESEESHLESGMQNMSI 241
           +LLE EE  L  G+ ++++
Sbjct: 408 RLLEGEEQRLCEGVGSVNV 426


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  134 bits (336), Expect = 1e-31
 Identities = 66/156 (42%), Positives = 108/156 (69%), Gaps = 6/156 (3%)

Query: 13  LLSLLNLEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQQKM 72
           LL+ LNLE+DPN Q V+++EKEQI++LN++FA+FI KVRFLEQQN +LETK    Q ++ 
Sbjct: 87  LLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC 146

Query: 73  AWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEINKCTEMEN 132
             SN+  +F+ YI   R + + +  +  +L +EL ++Q ++E +K KY++E++     EN
Sbjct: 147 CQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAEN 206

Query: 133 EFILIRKDMDDAYVNKAETEGLKSQRASLEATIADV 168
           EF+ ++KD+D AY+ K++ E      A++EA I ++
Sbjct: 207 EFVALKKDVDCAYLRKSDLE------ANVEALIQEI 236



 Score =  100 bits (250), Expect = 1e-21
 Identities = 87/259 (33%), Positives = 127/259 (49%), Gaps = 36/259 (13%)

Query: 12  RLLSLLN--LEVDPNIQAVQEQEKEQIRTLNNKFASFIGKVRFLEQQNNMLETKWSLLQQ 69
           RL S LN   EV    +   E+E     T  N+F +    V     + + LE     L Q
Sbjct: 175 RLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQ 234

Query: 70  Q----KMAWSNMGNMFKSYINNPRGQPDTLVQEKLKLKAELGNMQGLVEDFKNKYKDEI- 124
           +    +  +     + +S+I+      DT V  KL    +L NM  ++ + K +Y D + 
Sbjct: 235 EIDFLRRLYEEEILILQSHIS------DTSVVVKLDNSRDL-NMDCIIAEIKAQYDDIVT 287

Query: 125 -----------NKCTEMENEFI-----LIRKDMDDAYVNK------AETEGLKSQRASLE 162
                      +KC EM+   I     L R   +   +N+      AE E  K Q + LE
Sbjct: 288 RSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLE 347

Query: 163 ATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKLKNMKLALDIEIATYR 222
           A +A  +Q+GE A+ DA  KL++LE ALQ+A QDMA  + EYQ++ N KL LDIEIATYR
Sbjct: 348 AAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYR 407

Query: 223 KLLESEESHLESGMQNMSI 241
           +LLE EE  L  G+  +++
Sbjct: 408 RLLEGEEQRLCEGIGAVNV 426


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.126    0.342 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,977,976
Number of Sequences: 37866
Number of extensions: 399145
Number of successful extensions: 2196
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 122
Number of HSP's successfully gapped in prelim test: 203
Number of HSP's that attempted gapping in prelim test: 1618
Number of HSP's gapped (non-prelim): 659
length of query: 313
length of database: 18,247,518
effective HSP length: 102
effective length of query: 211
effective length of database: 14,385,186
effective search space: 3035274246
effective search space used: 3035274246
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.