Search of human proteins with 169163744

Search of human proteins with 169163744

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169163744 PREDICTED: similar to ACR [Homo sapiens]
         (299 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169163744 PREDICTED: similar to ACR [Homo sapiens]                 619   e-177
gi|169163027 PREDICTED: similar to Putative acrosin-like proteas...   593   e-170
gi|148613878 acrosin precursor [Homo sapiens]                         343   8e-95
gi|33695155 hepsin [Homo sapiens]                                     104   1e-22
gi|4504481 hepsin [Homo sapiens]                                      104   1e-22
gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo ...    99   6e-21
gi|167466250 transmembrane protease, serine 11A isoform 1 [Homo ...    99   6e-21
gi|33667063 transmembrane protease, serine 9 [Homo sapiens]            98   8e-21
gi|4505881 plasminogen [Homo sapiens]                                  96   3e-20
gi|194018492 transmembrane protease, serine 11F [Homo sapiens]         96   3e-20
gi|40254871 transmembrane protease, serine 11E [Homo sapiens]          96   5e-20
gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]        96   5e-20
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa...    94   2e-19
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap...    94   2e-19
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...    94   2e-19
gi|4758502 hyaluronan binding protein 2 preproprotein [Homo sapi...    93   2e-19
gi|187761337 transmembrane protease, serine 11B [Homo sapiens]         92   7e-19
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]          92   7e-19
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa...    91   2e-18
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa...    91   2e-18
gi|170932492 transmembrane protease, serine 5 [Homo sapiens]           91   2e-18
gi|4758508 transmembrane protease, serine 11D [Homo sapiens]           89   4e-18
gi|4504383 HGF activator preproprotein [Homo sapiens]                  88   8e-18
gi|110815798 ovochymase 1 [Homo sapiens]                               88   8e-18
gi|145275213 coagulation factor XII precursor [Homo sapiens]           86   3e-17
gi|117956391 protease, serine, 33 [Homo sapiens]                       86   5e-17
gi|239743017 PREDICTED: hypothetical protein XP_002342719 [Homo ...    84   1e-16
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]              84   1e-16
gi|4506153 prostasin preproprotein [Homo sapiens]                      84   2e-16
gi|4503627 coagulation factor XI precursor [Homo sapiens]              83   3e-16

>gi|169163744 PREDICTED: similar to ACR [Homo sapiens]
          Length = 299

 Score =  619 bits (1595), Expect = e-177
 Identities = 299/299 (100%), Positives = 299/299 (100%)

Query: 1   MFWVCPYLSLLPSALQVTSRSTPRVVGAAAVGARVAAAVGDPSVCGTLEKEQRWRMRRSI 60
           MFWVCPYLSLLPSALQVTSRSTPRVVGAAAVGARVAAAVGDPSVCGTLEKEQRWRMRRSI
Sbjct: 1   MFWVCPYLSLLPSALQVTSRSTPRVVGAAAVGARVAAAVGDPSVCGTLEKEQRWRMRRSI 60

Query: 61  GSARVWRRCPSFPCGLLGTDVQHMGRDLLTQLQQIPSAAEPRRSEEGQEAGGVAYSQTVG 120
           GSARVWRRCPSFPCGLLGTDVQHMGRDLLTQLQQIPSAAEPRRSEEGQEAGGVAYSQTVG
Sbjct: 61  GSARVWRRCPSFPCGLLGTDVQHMGRDLLTQLQQIPSAAEPRRSEEGQEAGGVAYSQTVG 120

Query: 121 ADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMC 180
           ADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMC
Sbjct: 121 ADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMC 180

Query: 181 KDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRVIQSATPPPPT 240
           KDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRVIQSATPPPPT
Sbjct: 181 KDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRVIQSATPPPPT 240

Query: 241 TRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSXXXXXXXSLLSGGWWC 299
           TRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPS       SLLSGGWWC
Sbjct: 241 TRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSXXXXXXXSLLSGGWWC 299


>gi|169163027 PREDICTED: similar to Putative acrosin-like protease
           [Homo sapiens]
          Length = 355

 Score =  593 bits (1529), Expect = e-170
 Identities = 280/283 (98%), Positives = 282/283 (99%)

Query: 1   MFWVCPYLSLLPSALQVTSRSTPRVVGAAAVGARVAAAVGDPSVCGTLEKEQRWRMRRSI 60
           MFWVCPYLSLLPSALQVTSRSTPRVVGAAAVGARVAAAVGDPSVCGTLEKEQRWRMRRSI
Sbjct: 1   MFWVCPYLSLLPSALQVTSRSTPRVVGAAAVGARVAAAVGDPSVCGTLEKEQRWRMRRSI 60

Query: 61  GSARVWRRCPSFPCGLLGTDVQHMGRDLLTQLQQIPSAAEPRRSEEGQEAGGVAYSQTVG 120
           GSARVWRRCPSFPCGLLGTDVQHMGRDLLTQLQQIPSAAEPRRSEEGQEAGGVAYSQTVG
Sbjct: 61  GSARVWRRCPSFPCGLLGTDVQHMGRDLLTQLQQIPSAAEPRRSEEGQEAGGVAYSQTVG 120

Query: 121 ADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMC 180
           ADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMC
Sbjct: 121 ADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMC 180

Query: 181 KDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRVIQSATPPPPT 240
           KDSKESA VVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALR+IQSATPPPPT
Sbjct: 181 KDSKESACVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSATPPPPT 240

Query: 241 TRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPS 283
           TRPPPIRPPFSHP+SAHLPWYFQPPPRPLPPRPPAAQPRPPPS
Sbjct: 241 TRPPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPPPS 283


>gi|148613878 acrosin precursor [Homo sapiens]
          Length = 421

 Score =  343 bits (881), Expect = 8e-95
 Identities = 159/177 (89%), Positives = 164/177 (92%)

Query: 107 GQEAGGVAYSQTVGADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGK 166
           G ++  VA    +    PRPSS+LMEARVDLIDLDLCNSTQWYN  VQPTNVCAGYPVGK
Sbjct: 173 GSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGK 232

Query: 167 IDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSN 226
           IDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSN
Sbjct: 233 IDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSN 292

Query: 227 ALRVIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPS 283
           ALR+IQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPS
Sbjct: 293 ALRMIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPS 349


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score =  104 bits (259), Expect = 1e-22
 Identities = 46/103 (44%), Positives = 65/103 (63%), Gaps = 2/103 (1%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKD--SK 184
           + +L EARV +I  D+CN   +Y   ++P   CAGYP G ID CQGDSGGP +C+D  S+
Sbjct: 306 AGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISR 365

Query: 185 ESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNA 227
              + + GI SWG GCA A++PG+YT    +  WI   I +++
Sbjct: 366 TPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHS 408


>gi|4504481 hepsin [Homo sapiens]
          Length = 417

 Score =  104 bits (259), Expect = 1e-22
 Identities = 46/103 (44%), Positives = 65/103 (63%), Gaps = 2/103 (1%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKD--SK 184
           + +L EARV +I  D+CN   +Y   ++P   CAGYP G ID CQGDSGGP +C+D  S+
Sbjct: 306 AGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISR 365

Query: 185 ESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNA 227
              + + GI SWG GCA A++PG+YT    +  WI   I +++
Sbjct: 366 TPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHS 408


>gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo
           sapiens]
          Length = 418

 Score = 98.6 bits (244), Expect = 6e-21
 Identities = 46/95 (48%), Positives = 60/95 (63%), Gaps = 1/95 (1%)

Query: 130 LMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYV 189
           L EARV +I  D+C   Q Y   ++P   CAGY  G  D C+GDSGGPL+ +D K++ Y 
Sbjct: 324 LREARVKIISDDVCKQPQVYGNDIKPGMFCAGYMEGIYDACRGDSGGPLVTRDLKDTWY- 382

Query: 190 VVGITSWGVGCARAKRPGIYTATWPYLNWIASKIG 224
           ++GI SWG  C +  +PG+YT    Y NWIASK G
Sbjct: 383 LIGIVSWGDNCGQKDKPGVYTQVTYYRNWIASKTG 417


>gi|167466250 transmembrane protease, serine 11A isoform 1 [Homo
           sapiens]
          Length = 421

 Score = 98.6 bits (244), Expect = 6e-21
 Identities = 46/95 (48%), Positives = 60/95 (63%), Gaps = 1/95 (1%)

Query: 130 LMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYV 189
           L EARV +I  D+C   Q Y   ++P   CAGY  G  D C+GDSGGPL+ +D K++ Y 
Sbjct: 327 LREARVKIISDDVCKQPQVYGNDIKPGMFCAGYMEGIYDACRGDSGGPLVTRDLKDTWY- 385

Query: 190 VVGITSWGVGCARAKRPGIYTATWPYLNWIASKIG 224
           ++GI SWG  C +  +PG+YT    Y NWIASK G
Sbjct: 386 LIGIVSWGDNCGQKDKPGVYTQVTYYRNWIASKTG 420


>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
          Length = 1059

 Score = 98.2 bits (243), Expect = 8e-21
 Identities = 51/131 (38%), Positives = 71/131 (54%), Gaps = 10/131 (7%)

Query: 129 MLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAY 188
           +L +A V+L+D  LC S   Y   +    VCAGY  GK+D+CQGDSGGPL+C++     +
Sbjct: 344 VLQKATVELLDQALCASL--YGHSLTDRMVCAGYLDGKVDSCQGDSGGPLVCEE-PSGRF 400

Query: 189 VVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRVIQSATPPPPTTRPPPIRP 248
            + GI SWG+GCA A+RPG+Y       +WI            +++ P  PT  P P  P
Sbjct: 401 FLAGIVSWGIGCAEARRPGVYARVTRLRDWILE-------ATTKASMPLAPTMAPAPAAP 453

Query: 249 PFSHPISAHLP 259
             + P S   P
Sbjct: 454 STAWPTSPESP 464



 Score = 91.7 bits (226), Expect = 7e-19
 Identities = 53/142 (37%), Positives = 75/142 (52%), Gaps = 11/142 (7%)

Query: 129 MLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAY 188
           +L +A V +ID   C+    YN  +    +CAG+  GK+D+CQGDSGGPL C+++    +
Sbjct: 644 LLQKASVGIIDQKTCSVL--YNFSLTDRMICAGFLEGKVDSCQGDSGGPLACEEA-PGVF 700

Query: 189 VVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRVIQSATPPPPTTRPPPIRP 248
            + GI SWG+GCA+ K+PG+YT       WI   + S  L +      PP TTR      
Sbjct: 701 YLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSSQPLPM-----SPPSTTRMLATTS 755

Query: 249 PFSHPISAHLPWYFQPPPRPLP 270
           P +   +A L      P RP P
Sbjct: 756 PRT---TAGLTVPGATPSRPTP 774



 Score = 78.2 bits (191), Expect = 8e-15
 Identities = 36/94 (38%), Positives = 52/94 (55%), Gaps = 3/94 (3%)

Query: 130  LMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYV 189
            L +A V L+    C   ++Y   +    +CAG+P G +D+C GD+GGPL C++     +V
Sbjct: 967  LQKAAVRLLSEQTCR--RFYPVQISSRMLCAGFPQGGVDSCSGDAGGPLACRE-PSGRWV 1023

Query: 190  VVGITSWGVGCARAKRPGIYTATWPYLNWIASKI 223
            + G+TSWG GC R   PG+YT       WI   I
Sbjct: 1024 LTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQHI 1057


>gi|4505881 plasminogen [Homo sapiens]
          Length = 810

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 41/100 (41%), Positives = 66/100 (66%), Gaps = 2/100 (2%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKES 186
           + +L EA++ +I+  +CN  ++ N  VQ T +CAG+  G  D+CQGDSGGPL+C   ++ 
Sbjct: 713 AGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVC--FEKD 770

Query: 187 AYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSN 226
            Y++ G+TSWG+GCAR  +PG+Y     ++ WI   + +N
Sbjct: 771 KYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN 810


>gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
          Length = 438

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 45/95 (47%), Positives = 59/95 (62%), Gaps = 2/95 (2%)

Query: 130 LMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYV 189
           L +ARV+ I  D+CN    Y+  + P  +CAG+  GKID C+GDSGGPL+        + 
Sbjct: 345 LRQARVETISTDVCNRKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVY--DNHDIWY 402

Query: 190 VVGITSWGVGCARAKRPGIYTATWPYLNWIASKIG 224
           +VGI SWG  CA  K+PG+YT    Y +WIASK G
Sbjct: 403 IVGIVSWGQSCALPKKPGVYTRVTKYRDWIASKTG 437


>gi|40254871 transmembrane protease, serine 11E [Homo sapiens]
          Length = 423

 Score = 95.5 bits (236), Expect = 5e-20
 Identities = 45/95 (47%), Positives = 59/95 (62%), Gaps = 1/95 (1%)

Query: 130 LMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYV 189
           L +A+V LID   CN  Q YN+ + P  +CAG   GK D CQGDSGGPL+  D+++  Y 
Sbjct: 329 LRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWY- 387

Query: 190 VVGITSWGVGCARAKRPGIYTATWPYLNWIASKIG 224
           + GI SWG  CA+  +PG+YT      +WI SK G
Sbjct: 388 LAGIVSWGDECAKPNKPGVYTRVTALRDWITSKTG 422


>gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]
          Length = 423

 Score = 95.5 bits (236), Expect = 5e-20
 Identities = 45/95 (47%), Positives = 59/95 (62%), Gaps = 1/95 (1%)

Query: 130 LMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYV 189
           L +A+V LID   CN  Q YN+ + P  +CAG   GK D CQGDSGGPL+  D+++  Y 
Sbjct: 329 LRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWY- 387

Query: 190 VVGITSWGVGCARAKRPGIYTATWPYLNWIASKIG 224
           + GI SWG  CA+  +PG+YT      +WI SK G
Sbjct: 388 LAGIVSWGDECAKPNKPGVYTRVTALRDWITSKTG 422


>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
           sapiens]
          Length = 432

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 45/93 (48%), Positives = 56/93 (60%), Gaps = 3/93 (3%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKES 186
           S +L++A V +ID   CN+   Y   V    +CAG P G +DTCQGDSGGPLM +  +  
Sbjct: 335 SDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQ-- 392

Query: 187 AYVVVGITSWGVGCARAKRPGIYTATWPYLNWI 219
            + VVGI SWG GC     PG+YT    YLNWI
Sbjct: 393 -WHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 424


>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
           sapiens]
          Length = 437

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 45/93 (48%), Positives = 56/93 (60%), Gaps = 3/93 (3%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKES 186
           S +L++A V +ID   CN+   Y   V    +CAG P G +DTCQGDSGGPLM +  +  
Sbjct: 340 SDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQ-- 397

Query: 187 AYVVVGITSWGVGCARAKRPGIYTATWPYLNWI 219
            + VVGI SWG GC     PG+YT    YLNWI
Sbjct: 398 -WHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 429


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 48/119 (40%), Positives = 69/119 (57%), Gaps = 5/119 (4%)

Query: 104 SEEGQEAGGVAYSQTVGADTPRP---SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCA 160
           SEE    G V ++   GA        S +L  A V LI   +CN    Y   + P+ +CA
Sbjct: 328 SEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCA 387

Query: 161 GYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWI 219
           GY  G +D+CQGDSGGPL+C++ +   + +VG TS+G+GCA   +PG+YT    +L+WI
Sbjct: 388 GYLTGGVDSCQGDSGGPLVCQERR--LWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWI 444


>gi|4758502 hyaluronan binding protein 2 preproprotein [Homo
           sapiens]
          Length = 560

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 56/135 (41%), Positives = 75/135 (55%), Gaps = 14/135 (10%)

Query: 95  IPSAAEPRRSEEGQEAGGVAYSQTVGADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQ 154
           +P  + P  SE      GV        +T + S  L++A+V LI   LCNS Q Y+  + 
Sbjct: 436 LPDGSFPSGSECHISGWGVT-------ETGKGSRQLLDAKVKLIANTLCNSRQLYDHMID 488

Query: 155 PTNVCAG--YPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTAT 212
            + +CAG     G+ DTCQGDSGGPL C+  K+  Y V GI SWG+ C   KRPG+YT  
Sbjct: 489 DSMICAGNLQKPGQ-DTCQGDSGGPLTCE--KDGTYYVYGIVSWGLEC--GKRPGVYTQV 543

Query: 213 WPYLNWIASKIGSNA 227
             +LNWI + I S +
Sbjct: 544 TKFLNWIKATIKSES 558


>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
          Length = 416

 Score = 91.7 bits (226), Expect = 7e-19
 Identities = 43/96 (44%), Positives = 60/96 (62%), Gaps = 1/96 (1%)

Query: 129 MLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAY 188
           +L E  + +ID  +CN++  Y+  V  T +CAG+  G+ D CQ DSGGPL   DS+ + +
Sbjct: 321 ILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSR-NIW 379

Query: 189 VVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIG 224
            +VGI SWG GC +  +PG+YT    Y NWI SK G
Sbjct: 380 HLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKTG 415


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score = 91.7 bits (226), Expect = 7e-19
 Identities = 43/101 (42%), Positives = 62/101 (61%), Gaps = 2/101 (1%)

Query: 125 RPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSK 184
           + S  L E +V+LID   CN    Y+ ++ P  +CAG   G  D+CQGDSGGPL+C+  +
Sbjct: 462 KTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCE--Q 519

Query: 185 ESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGS 225
            + + + G+TSWG GC +  +PG+YT     L WI SK+ S
Sbjct: 520 NNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMES 560


>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
           sapiens]
          Length = 529

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 42/95 (44%), Positives = 61/95 (64%), Gaps = 2/95 (2%)

Query: 125 RPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSK 184
           + S +L  A+V LI+   CNS   Y+  + P  +CAG+  G +D+CQGDSGGPL+   SK
Sbjct: 429 KTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLV--TSK 486

Query: 185 ESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWI 219
            + + ++G TSWG GCA+A RPG+Y     + +WI
Sbjct: 487 NNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521


>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
           sapiens]
          Length = 492

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 42/95 (44%), Positives = 61/95 (64%), Gaps = 2/95 (2%)

Query: 125 RPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSK 184
           + S +L  A+V LI+   CNS   Y+  + P  +CAG+  G +D+CQGDSGGPL+   SK
Sbjct: 392 KTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLV--TSK 449

Query: 185 ESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWI 219
            + + ++G TSWG GCA+A RPG+Y     + +WI
Sbjct: 450 NNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 484


>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
          Length = 457

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 42/93 (45%), Positives = 55/93 (59%), Gaps = 2/93 (2%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKES 186
           S ML +  V L    LCNS+  Y+  + P  +CAGY  G+ D CQGDSGGPL+C D    
Sbjct: 358 SDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVCPDG--D 415

Query: 187 AYVVVGITSWGVGCARAKRPGIYTATWPYLNWI 219
            + +VG+ SWG GCA    PG+Y     +L+WI
Sbjct: 416 TWRLVGVVSWGRGCAEPNHPGVYAKVAEFLDWI 448


>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
          Length = 418

 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 41/95 (43%), Positives = 58/95 (61%), Gaps = 1/95 (1%)

Query: 130 LMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYV 189
           L + +V +I  D+CN+   YN  +    +CAG P G +D CQGDSGGPL+ +DS+   + 
Sbjct: 324 LRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRR-LWF 382

Query: 190 VVGITSWGVGCARAKRPGIYTATWPYLNWIASKIG 224
           +VGI SWG  C    +PG+YT    YL+WI  + G
Sbjct: 383 IVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQTG 417


>gi|4504383 HGF activator preproprotein [Homo sapiens]
          Length = 655

 Score = 88.2 bits (217), Expect = 8e-18
 Identities = 44/97 (45%), Positives = 56/97 (57%), Gaps = 2/97 (2%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKES 186
           SS L EA V L+    C+S + Y   + P  +CAGY   K D CQGDSGGPL C+  K  
Sbjct: 551 SSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACE--KNG 608

Query: 187 AYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKI 223
              + GI SWG GC R  +PG+YT    Y++WI  +I
Sbjct: 609 VAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRI 645


>gi|110815798 ovochymase 1 [Homo sapiens]
          Length = 1134

 Score = 88.2 bits (217), Expect = 8e-18
 Identities = 58/186 (31%), Positives = 92/186 (49%), Gaps = 17/186 (9%)

Query: 95  IPSAAEPRRSEEGQEAGGVAYSQTVGADTPRPSSMLMEARVDLIDLDLCNSTQWYNEH-- 152
           +P +AEP  S E     G     ++ AD    +S L + +V +++ ++C  T +Y+ H  
Sbjct: 685 LPHSAEPLFSSEICAVTGWG---SISADGGL-ASRLQQIQVHVLEREVCEHT-YYSAHPG 739

Query: 153 -VQPTNVCAGYPV-GKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYT 210
            +    +CAG+   G+ D CQGDSGGPL+C+  +   +V+ GI SWG GC +  +PG++ 
Sbjct: 740 GITEKMICAGFAASGEKDFCQGDSGGPLVCRH-ENGPFVLYGIVSWGAGCVQPWKPGVFA 798

Query: 211 ATWPYLNWIASKIG-------SNALRVIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQ 263
               +L+WI SKI        +N  + ++   PPP  +      P          P  F 
Sbjct: 799 RVMIFLDWIQSKINGPASLQTNNKCKTLKQQLPPPTPSPDSASWPGCCSEAELEKPRGFF 858

Query: 264 PPPRPL 269
           P PR L
Sbjct: 859 PTPRYL 864



 Score = 62.0 bits (149), Expect = 6e-10
 Identities = 39/108 (36%), Positives = 59/108 (54%), Gaps = 7/108 (6%)

Query: 104 SEEGQEAGGVAYSQTVG--ADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQP---TNV 158
           S++  E G +  S   G  + T   S++L E  + ++D   CN T   + ++ P   T +
Sbjct: 163 SDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACN-TVLKSMNLPPLGRTML 221

Query: 159 CAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRP 206
           CAG+P   +D CQGDSGGPL+C+      +++ GITSW  GCA    P
Sbjct: 222 CAGFPDWGMDACQGDSGGPLVCRRG-GGIWILAGITSWVAGCAGGSVP 268


>gi|145275213 coagulation factor XII precursor [Homo sapiens]
          Length = 615

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 40/94 (42%), Positives = 56/94 (59%), Gaps = 1/94 (1%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKD-SKE 185
           +S L EA+V  + L+ C++   +   + P  +CAG+  G  D CQGDSGGPL+C+D + E
Sbjct: 516 ASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAE 575

Query: 186 SAYVVVGITSWGVGCARAKRPGIYTATWPYLNWI 219
               + GI SWG GC    +PG+YT    YL WI
Sbjct: 576 RRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAWI 609


>gi|117956391 protease, serine, 33 [Homo sapiens]
          Length = 280

 Score = 85.5 bits (210), Expect = 5e-17
 Identities = 43/101 (42%), Positives = 56/101 (55%), Gaps = 9/101 (8%)

Query: 130 LMEARVDLIDLDLCNSTQWYNEHVQ-------PTNVCAGYPVGKIDTCQGDSGGPLMCKD 182
           L   RV L+D   C+        V        P ++CAGYP G  D CQGDSGGPL C  
Sbjct: 180 LQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQ 239

Query: 183 SKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKI 223
           S   ++V+VG+ SWG GCA   RPG+YT+   Y  WI +++
Sbjct: 240 S--GSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARV 278


>gi|239743017 PREDICTED: hypothetical protein XP_002342719 [Homo
           sapiens]
          Length = 299

 Score = 84.3 bits (207), Expect = 1e-16
 Identities = 38/115 (33%), Positives = 66/115 (57%), Gaps = 2/115 (1%)

Query: 112 GVAYSQTVGADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQ 171
           G   S    A  P   +   + ++ +I+  +CN  ++ N  ++ T +CA +  G  D+C+
Sbjct: 187 GSGKSLFYAAHVPLGLAFSRKPQLLVIENKVCNRYEYLNGRIKSTELCARHLAGGTDSCK 246

Query: 172 GDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSN 226
           GDSGGPL+C   ++  Y++ G+TSWG+GCAR  +PG+Y     ++ WI   + +N
Sbjct: 247 GDSGGPLVC--FEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN 299


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score = 84.3 bits (207), Expect = 1e-16
 Identities = 40/99 (40%), Positives = 61/99 (61%), Gaps = 3/99 (3%)

Query: 128 SMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESA 187
           ++L +  + L+  + C   ++ +  +    VCAGY  G  D C+GDSGGPL+CK +    
Sbjct: 533 NILQKVNIPLVTNEECQK-RYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHN--GM 589

Query: 188 YVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSN 226
           + +VGITSWG GCAR ++PG+YT    Y++WI  K  S+
Sbjct: 590 WRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSS 628


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 50/125 (40%), Positives = 59/125 (47%), Gaps = 15/125 (12%)

Query: 123 TPRPSSMLMEARVDLIDLDLCNSTQWYN--------EHVQPTNVCAGYPVGKIDTCQGDS 174
           TP+P   L +  V LI  + CN    YN          VQ   VCAGY  G  D CQGDS
Sbjct: 184 TPKP---LQQLEVPLISRETCNCL--YNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDS 238

Query: 175 GGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRVIQSA 234
           GGPL C    E  + + GI SWG  C    RPG+YT    Y +WI SK+     RV+   
Sbjct: 239 GGPLSCP--VEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQT 296

Query: 235 TPPPP 239
               P
Sbjct: 297 QESQP 301


>gi|4503627 coagulation factor XI precursor [Homo sapiens]
          Length = 625

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 39/93 (41%), Positives = 58/93 (62%), Gaps = 3/93 (3%)

Query: 130 LMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYV 189
           L +A++ L+  + C   ++    +    +CAGY  G  D C+GDSGGPL CK ++   + 
Sbjct: 532 LQKAKIPLVTNEECQK-RYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNE--VWH 588

Query: 190 VVGITSWGVGCARAKRPGIYTATWPYLNWIASK 222
           +VGITSWG GCA+ +RPG+YT    Y++WI  K
Sbjct: 589 LVGITSWGEGCAQRERPGVYTNVVEYVDWILEK 621


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.452 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,654,832
Number of Sequences: 37866
Number of extensions: 1010369
Number of successful extensions: 17525
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 504
Number of HSP's successfully gapped in prelim test: 498
Number of HSP's that attempted gapping in prelim test: 8161
Number of HSP's gapped (non-prelim): 5578
length of query: 299
length of database: 18,247,518
effective HSP length: 102
effective length of query: 197
effective length of database: 14,385,186
effective search space: 2833881642
effective search space used: 2833881642
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.