Search of human proteins with 169163027

Search of human proteins with 169163027

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169163027 PREDICTED: similar to Putative acrosin-like
protease [Homo sapiens]
         (355 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169163027 PREDICTED: similar to Putative acrosin-like proteas...   754   0.0  
gi|169163744 PREDICTED: similar to ACR [Homo sapiens]                 593   e-170
gi|148613878 acrosin precursor [Homo sapiens]                         492   e-139
gi|33695155 hepsin [Homo sapiens]                                     103   3e-22
gi|4504481 hepsin [Homo sapiens]                                      103   3e-22
gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo ...    96   5e-20
gi|167466250 transmembrane protease, serine 11A isoform 1 [Homo ...    96   5e-20
gi|33667063 transmembrane protease, serine 9 [Homo sapiens]            96   5e-20
gi|194018492 transmembrane protease, serine 11F [Homo sapiens]         95   1e-19
gi|40254871 transmembrane protease, serine 11E [Homo sapiens]          93   3e-19
gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]        93   3e-19
gi|4505881 plasminogen [Homo sapiens]                                  93   4e-19
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa...    92   5e-19
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap...    92   5e-19
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...    92   7e-19
gi|187761337 transmembrane protease, serine 11B [Homo sapiens]         90   3e-18
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]          90   3e-18
gi|4758502 hyaluronan binding protein 2 preproprotein [Homo sapi...    90   4e-18
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa...    89   6e-18
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa...    89   6e-18
gi|4504383 HGF activator preproprotein [Homo sapiens]                  89   6e-18
gi|170932492 transmembrane protease, serine 5 [Homo sapiens]           89   6e-18
gi|4758508 transmembrane protease, serine 11D [Homo sapiens]           88   1e-17
gi|145275213 coagulation factor XII precursor [Homo sapiens]           86   4e-17
gi|110815798 ovochymase 1 [Homo sapiens]                               86   5e-17
gi|117956391 protease, serine, 33 [Homo sapiens]                       84   2e-16
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]              83   4e-16
gi|4503627 coagulation factor XI precursor [Homo sapiens]              82   1e-15
gi|11545839 protease, serine, 22 [Homo sapiens]                        82   1e-15
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]            81   1e-15

>gi|169163027 PREDICTED: similar to Putative acrosin-like protease
           [Homo sapiens]
          Length = 355

 Score =  754 bits (1946), Expect = 0.0
 Identities = 355/355 (100%), Positives = 355/355 (100%)

Query: 1   MFWVCPYLSLLPSALQVTSRSTPRVVGAAAVGARVAAAVGDPSVCGTLEKEQRWRMRRSI 60
           MFWVCPYLSLLPSALQVTSRSTPRVVGAAAVGARVAAAVGDPSVCGTLEKEQRWRMRRSI
Sbjct: 1   MFWVCPYLSLLPSALQVTSRSTPRVVGAAAVGARVAAAVGDPSVCGTLEKEQRWRMRRSI 60

Query: 61  GSARVWRRCPSFPCGLLGTDVQHMGRDLLTQLQQIPSAAEPRRSEEGQEAGGVAYSQTVG 120
           GSARVWRRCPSFPCGLLGTDVQHMGRDLLTQLQQIPSAAEPRRSEEGQEAGGVAYSQTVG
Sbjct: 61  GSARVWRRCPSFPCGLLGTDVQHMGRDLLTQLQQIPSAAEPRRSEEGQEAGGVAYSQTVG 120

Query: 121 ADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMC 180
           ADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMC
Sbjct: 121 ADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMC 180

Query: 181 KDSKESACVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSATPPPPT 240
           KDSKESACVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSATPPPPT
Sbjct: 181 KDSKESACVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSATPPPPT 240

Query: 241 TRPPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPPSPLPPPPP 300
           TRPPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPPSPLPPPPP
Sbjct: 241 TRPPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPPSPLPPPPP 300

Query: 301 PPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGKNHYDMETTELPELTSTS 355
           PPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGKNHYDMETTELPELTSTS
Sbjct: 301 PPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGKNHYDMETTELPELTSTS 355


>gi|169163744 PREDICTED: similar to ACR [Homo sapiens]
          Length = 299

 Score =  593 bits (1529), Expect = e-170
 Identities = 280/283 (98%), Positives = 282/283 (99%)

Query: 1   MFWVCPYLSLLPSALQVTSRSTPRVVGAAAVGARVAAAVGDPSVCGTLEKEQRWRMRRSI 60
           MFWVCPYLSLLPSALQVTSRSTPRVVGAAAVGARVAAAVGDPSVCGTLEKEQRWRMRRSI
Sbjct: 1   MFWVCPYLSLLPSALQVTSRSTPRVVGAAAVGARVAAAVGDPSVCGTLEKEQRWRMRRSI 60

Query: 61  GSARVWRRCPSFPCGLLGTDVQHMGRDLLTQLQQIPSAAEPRRSEEGQEAGGVAYSQTVG 120
           GSARVWRRCPSFPCGLLGTDVQHMGRDLLTQLQQIPSAAEPRRSEEGQEAGGVAYSQTVG
Sbjct: 61  GSARVWRRCPSFPCGLLGTDVQHMGRDLLTQLQQIPSAAEPRRSEEGQEAGGVAYSQTVG 120

Query: 121 ADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMC 180
           ADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMC
Sbjct: 121 ADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMC 180

Query: 181 KDSKESACVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSATPPPPT 240
           KDSKESA VVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALR+IQSATPPPPT
Sbjct: 181 KDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRVIQSATPPPPT 240

Query: 241 TRPPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPPPS 283
           TRPPPIRPPFSHP+SAHLPWYFQPPPRPLPPRPPAAQPRPPPS
Sbjct: 241 TRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPS 283


>gi|148613878 acrosin precursor [Homo sapiens]
          Length = 421

 Score =  492 bits (1266), Expect = e-139
 Identities = 229/249 (91%), Positives = 234/249 (93%)

Query: 107 GQEAGGVAYSQTVGADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGK 166
           G ++  VA    +    PRPSS+LMEARVDLIDLDLCNSTQWYN  VQPTNVCAGYPVGK
Sbjct: 173 GSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGK 232

Query: 167 IDTCQGDSGGPLMCKDSKESACVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSN 226
           IDTCQGDSGGPLMCKDSKESA VVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSN
Sbjct: 233 IDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSN 292

Query: 227 ALRMIQSATPPPPTTRPPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPP 286
           ALRMIQSATPPPPTTRPPPIRPPFSHP+SAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPP
Sbjct: 293 ALRMIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPP 352

Query: 287 PPPPPPSPLPPPPPPPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGKNHYDMETT 346
           PPPPP SPLPPPPPPPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGKNHYDMETT
Sbjct: 353 PPPPPASPLPPPPPPPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGKNHYDMETT 412

Query: 347 ELPELTSTS 355
           ELPELTSTS
Sbjct: 413 ELPELTSTS 421


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score =  103 bits (256), Expect = 3e-22
 Identities = 50/109 (45%), Positives = 66/109 (60%), Gaps = 4/109 (3%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKD--SK 184
           + +L EARV +I  D+CN   +Y   ++P   CAGYP G ID CQGDSGGP +C+D  S+
Sbjct: 306 AGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISR 365

Query: 185 ESACVVVGITSWGVGCARAKRPGIYTATWPYLNWI--ASKIGSNALRMI 231
                + GI SWG GCA A++PG+YT    +  WI  A K  S A  M+
Sbjct: 366 TPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGMV 414


>gi|4504481 hepsin [Homo sapiens]
          Length = 417

 Score =  103 bits (256), Expect = 3e-22
 Identities = 50/109 (45%), Positives = 66/109 (60%), Gaps = 4/109 (3%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKD--SK 184
           + +L EARV +I  D+CN   +Y   ++P   CAGYP G ID CQGDSGGP +C+D  S+
Sbjct: 306 AGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISR 365

Query: 185 ESACVVVGITSWGVGCARAKRPGIYTATWPYLNWI--ASKIGSNALRMI 231
                + GI SWG GCA A++PG+YT    +  WI  A K  S A  M+
Sbjct: 366 TPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGMV 414


>gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo
           sapiens]
          Length = 418

 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 45/95 (47%), Positives = 59/95 (62%), Gaps = 1/95 (1%)

Query: 130 LMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESACV 189
           L EARV +I  D+C   Q Y   ++P   CAGY  G  D C+GDSGGPL+ +D K++   
Sbjct: 324 LREARVKIISDDVCKQPQVYGNDIKPGMFCAGYMEGIYDACRGDSGGPLVTRDLKDT-WY 382

Query: 190 VVGITSWGVGCARAKRPGIYTATWPYLNWIASKIG 224
           ++GI SWG  C +  +PG+YT    Y NWIASK G
Sbjct: 383 LIGIVSWGDNCGQKDKPGVYTQVTYYRNWIASKTG 417


>gi|167466250 transmembrane protease, serine 11A isoform 1 [Homo
           sapiens]
          Length = 421

 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 45/95 (47%), Positives = 59/95 (62%), Gaps = 1/95 (1%)

Query: 130 LMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESACV 189
           L EARV +I  D+C   Q Y   ++P   CAGY  G  D C+GDSGGPL+ +D K++   
Sbjct: 327 LREARVKIISDDVCKQPQVYGNDIKPGMFCAGYMEGIYDACRGDSGGPLVTRDLKDT-WY 385

Query: 190 VVGITSWGVGCARAKRPGIYTATWPYLNWIASKIG 224
           ++GI SWG  C +  +PG+YT    Y NWIASK G
Sbjct: 386 LIGIVSWGDNCGQKDKPGVYTQVTYYRNWIASKTG 420


>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
          Length = 1059

 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 51/131 (38%), Positives = 70/131 (53%), Gaps = 10/131 (7%)

Query: 129 MLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAC 188
           +L +A V+L+D  LC S   Y   +    VCAGY  GK+D+CQGDSGGPL+C++      
Sbjct: 344 VLQKATVELLDQALCASL--YGHSLTDRMVCAGYLDGKVDSCQGDSGGPLVCEE-PSGRF 400

Query: 189 VVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSATPPPPTTRPPPIRP 248
            + GI SWG+GCA A+RPG+Y       +WI            +++ P  PT  P P  P
Sbjct: 401 FLAGIVSWGIGCAEARRPGVYARVTRLRDWILE-------ATTKASMPLAPTMAPAPAAP 453

Query: 249 PFSHPLSAHLP 259
             + P S   P
Sbjct: 454 STAWPTSPESP 464



 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 63/182 (34%), Positives = 84/182 (46%), Gaps = 15/182 (8%)

Query: 129 MLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAC 188
           +L +A V +ID   C+    YN  +    +CAG+  GK+D+CQGDSGGPL C+++     
Sbjct: 644 LLQKASVGIIDQKTCSVL--YNFSLTDRMICAGFLEGKVDSCQGDSGGPLACEEA-PGVF 700

Query: 189 VVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSATPPPPTTRPPPIRP 248
            + GI SWG+GCA+ K+PG+YT       WI   + S  L M      PP TTR      
Sbjct: 701 YLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSSQPLPM-----SPPSTTRMLATTS 755

Query: 249 PFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPPSPLPPPPPPPPPTPSS 308
           P +   +A L      P RP     P A  R    P        S       P P  P +
Sbjct: 756 PRT---TAGLTVPGATPSRP----TPGAASRVTGQPANSTLSAVSTTARGQTPFPDAPEA 808

Query: 309 TT 310
           TT
Sbjct: 809 TT 810



 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 36/94 (38%), Positives = 51/94 (54%), Gaps = 3/94 (3%)

Query: 130  LMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESACV 189
            L +A V L+    C   ++Y   +    +CAG+P G +D+C GD+GGPL C++      V
Sbjct: 967  LQKAAVRLLSEQTCR--RFYPVQISSRMLCAGFPQGGVDSCSGDAGGPLACRE-PSGRWV 1023

Query: 190  VVGITSWGVGCARAKRPGIYTATWPYLNWIASKI 223
            + G+TSWG GC R   PG+YT       WI   I
Sbjct: 1024 LTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQHI 1057


>gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
          Length = 438

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 45/95 (47%), Positives = 58/95 (61%), Gaps = 2/95 (2%)

Query: 130 LMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESACV 189
           L +ARV+ I  D+CN    Y+  + P  +CAG+  GKID C+GDSGGPL+          
Sbjct: 345 LRQARVETISTDVCNRKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVY--DNHDIWY 402

Query: 190 VVGITSWGVGCARAKRPGIYTATWPYLNWIASKIG 224
           +VGI SWG  CA  K+PG+YT    Y +WIASK G
Sbjct: 403 IVGIVSWGQSCALPKKPGVYTRVTKYRDWIASKTG 437


>gi|40254871 transmembrane protease, serine 11E [Homo sapiens]
          Length = 423

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 44/95 (46%), Positives = 58/95 (61%), Gaps = 1/95 (1%)

Query: 130 LMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESACV 189
           L +A+V LID   CN  Q YN+ + P  +CAG   GK D CQGDSGGPL+  D+++    
Sbjct: 329 LRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARD-IWY 387

Query: 190 VVGITSWGVGCARAKRPGIYTATWPYLNWIASKIG 224
           + GI SWG  CA+  +PG+YT      +WI SK G
Sbjct: 388 LAGIVSWGDECAKPNKPGVYTRVTALRDWITSKTG 422


>gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]
          Length = 423

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 44/95 (46%), Positives = 58/95 (61%), Gaps = 1/95 (1%)

Query: 130 LMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESACV 189
           L +A+V LID   CN  Q YN+ + P  +CAG   GK D CQGDSGGPL+  D+++    
Sbjct: 329 LRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARD-IWY 387

Query: 190 VVGITSWGVGCARAKRPGIYTATWPYLNWIASKIG 224
           + GI SWG  CA+  +PG+YT      +WI SK G
Sbjct: 388 LAGIVSWGDECAKPNKPGVYTRVTALRDWITSKTG 422


>gi|4505881 plasminogen [Homo sapiens]
          Length = 810

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 40/100 (40%), Positives = 65/100 (65%), Gaps = 2/100 (2%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKES 186
           + +L EA++ +I+  +CN  ++ N  VQ T +CAG+  G  D+CQGDSGGPL+C   ++ 
Sbjct: 713 AGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVC--FEKD 770

Query: 187 ACVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSN 226
             ++ G+TSWG+GCAR  +PG+Y     ++ WI   + +N
Sbjct: 771 KYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN 810


>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
           sapiens]
          Length = 432

 Score = 92.4 bits (228), Expect = 5e-19
 Identities = 45/93 (48%), Positives = 55/93 (59%), Gaps = 3/93 (3%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKES 186
           S +L++A V +ID   CN+   Y   V    +CAG P G +DTCQGDSGGPLM +  +  
Sbjct: 335 SDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWH 394

Query: 187 ACVVVGITSWGVGCARAKRPGIYTATWPYLNWI 219
              VVGI SWG GC     PG+YT    YLNWI
Sbjct: 395 ---VVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 424


>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
           sapiens]
          Length = 437

 Score = 92.4 bits (228), Expect = 5e-19
 Identities = 45/93 (48%), Positives = 55/93 (59%), Gaps = 3/93 (3%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKES 186
           S +L++A V +ID   CN+   Y   V    +CAG P G +DTCQGDSGGPLM +  +  
Sbjct: 340 SDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWH 399

Query: 187 ACVVVGITSWGVGCARAKRPGIYTATWPYLNWI 219
              VVGI SWG GC     PG+YT    YLNWI
Sbjct: 400 ---VVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 429


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score = 92.0 bits (227), Expect = 7e-19
 Identities = 48/119 (40%), Positives = 68/119 (57%), Gaps = 5/119 (4%)

Query: 104 SEEGQEAGGVAYSQTVGADTPRP---SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCA 160
           SEE    G V ++   GA        S +L  A V LI   +CN    Y   + P+ +CA
Sbjct: 328 SEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCA 387

Query: 161 GYPVGKIDTCQGDSGGPLMCKDSKESACVVVGITSWGVGCARAKRPGIYTATWPYLNWI 219
           GY  G +D+CQGDSGGPL+C++ +     +VG TS+G+GCA   +PG+YT    +L+WI
Sbjct: 388 GYLTGGVDSCQGDSGGPLVCQERR--LWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWI 444


>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
          Length = 416

 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 43/96 (44%), Positives = 59/96 (61%), Gaps = 1/96 (1%)

Query: 129 MLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAC 188
           +L E  + +ID  +CN++  Y+  V  T +CAG+  G+ D CQ DSGGPL   DS+ +  
Sbjct: 321 ILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSR-NIW 379

Query: 189 VVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIG 224
            +VGI SWG GC +  +PG+YT    Y NWI SK G
Sbjct: 380 HLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKTG 415


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 43/101 (42%), Positives = 61/101 (60%), Gaps = 2/101 (1%)

Query: 125 RPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSK 184
           + S  L E +V+LID   CN    Y+ ++ P  +CAG   G  D+CQGDSGGPL+C+  +
Sbjct: 462 KTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCE--Q 519

Query: 185 ESACVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGS 225
            +   + G+TSWG GC +  +PG+YT     L WI SK+ S
Sbjct: 520 NNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMES 560


>gi|4758502 hyaluronan binding protein 2 preproprotein [Homo
           sapiens]
          Length = 560

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 55/135 (40%), Positives = 74/135 (54%), Gaps = 14/135 (10%)

Query: 95  IPSAAEPRRSEEGQEAGGVAYSQTVGADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQ 154
           +P  + P  SE      GV        +T + S  L++A+V LI   LCNS Q Y+  + 
Sbjct: 436 LPDGSFPSGSECHISGWGVT-------ETGKGSRQLLDAKVKLIANTLCNSRQLYDHMID 488

Query: 155 PTNVCAG--YPVGKIDTCQGDSGGPLMCKDSKESACVVVGITSWGVGCARAKRPGIYTAT 212
            + +CAG     G+ DTCQGDSGGPL C+  K+    V GI SWG+ C   KRPG+YT  
Sbjct: 489 DSMICAGNLQKPGQ-DTCQGDSGGPLTCE--KDGTYYVYGIVSWGLEC--GKRPGVYTQV 543

Query: 213 WPYLNWIASKIGSNA 227
             +LNWI + I S +
Sbjct: 544 TKFLNWIKATIKSES 558


>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
           sapiens]
          Length = 529

 Score = 89.0 bits (219), Expect = 6e-18
 Identities = 42/95 (44%), Positives = 60/95 (63%), Gaps = 2/95 (2%)

Query: 125 RPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSK 184
           + S +L  A+V LI+   CNS   Y+  + P  +CAG+  G +D+CQGDSGGPL+   SK
Sbjct: 429 KTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLV--TSK 486

Query: 185 ESACVVVGITSWGVGCARAKRPGIYTATWPYLNWI 219
            +   ++G TSWG GCA+A RPG+Y     + +WI
Sbjct: 487 NNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521


>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
           sapiens]
          Length = 492

 Score = 89.0 bits (219), Expect = 6e-18
 Identities = 42/95 (44%), Positives = 60/95 (63%), Gaps = 2/95 (2%)

Query: 125 RPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSK 184
           + S +L  A+V LI+   CNS   Y+  + P  +CAG+  G +D+CQGDSGGPL+   SK
Sbjct: 392 KTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLV--TSK 449

Query: 185 ESACVVVGITSWGVGCARAKRPGIYTATWPYLNWI 219
            +   ++G TSWG GCA+A RPG+Y     + +WI
Sbjct: 450 NNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 484


>gi|4504383 HGF activator preproprotein [Homo sapiens]
          Length = 655

 Score = 89.0 bits (219), Expect = 6e-18
 Identities = 44/97 (45%), Positives = 56/97 (57%), Gaps = 2/97 (2%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKES 186
           SS L EA V L+    C+S + Y   + P  +CAGY   K D CQGDSGGPL C+  K  
Sbjct: 551 SSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACE--KNG 608

Query: 187 ACVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKI 223
              + GI SWG GC R  +PG+YT    Y++WI  +I
Sbjct: 609 VAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRI 645



 Score = 28.5 bits (62), Expect = 9.6
 Identities = 31/98 (31%), Positives = 35/98 (35%), Gaps = 22/98 (22%)

Query: 239 PTTRPPPIRPPFSHPLSAHL--PWYFQPPP---RPLPPRPPAA--------------QPR 279
           P+  PPP   PF   L   L  P  FQP P   R   P P A                  
Sbjct: 8   PSPWPPPGLGPFLLLLLLLLLLPRGFQPQPGGNRTESPEPNATATPAIPTILVTSVTSET 67

Query: 280 PPPSPPPPPPPPPSPLPPPPPPPPPTPSSTTKLPQGLS 317
           P  S P    P    LPPPP      PSS++   Q L+
Sbjct: 68  PATSAPEAEGPQSGGLPPPPR---AVPSSSSPQAQALT 102


>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
          Length = 457

 Score = 89.0 bits (219), Expect = 6e-18
 Identities = 42/93 (45%), Positives = 54/93 (58%), Gaps = 2/93 (2%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKES 186
           S ML +  V L    LCNS+  Y+  + P  +CAGY  G+ D CQGDSGGPL+C D    
Sbjct: 358 SDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVCPDG--D 415

Query: 187 ACVVVGITSWGVGCARAKRPGIYTATWPYLNWI 219
              +VG+ SWG GCA    PG+Y     +L+WI
Sbjct: 416 TWRLVGVVSWGRGCAEPNHPGVYAKVAEFLDWI 448


>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
          Length = 418

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 41/95 (43%), Positives = 57/95 (60%), Gaps = 1/95 (1%)

Query: 130 LMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESACV 189
           L + +V +I  D+CN+   YN  +    +CAG P G +D CQGDSGGPL+ +DS+     
Sbjct: 324 LRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRR-LWF 382

Query: 190 VVGITSWGVGCARAKRPGIYTATWPYLNWIASKIG 224
           +VGI SWG  C    +PG+YT    YL+WI  + G
Sbjct: 383 IVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQTG 417


>gi|145275213 coagulation factor XII precursor [Homo sapiens]
          Length = 615

 Score = 86.3 bits (212), Expect = 4e-17
 Identities = 40/94 (42%), Positives = 56/94 (59%), Gaps = 1/94 (1%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKD-SKE 185
           +S L EA+V  + L+ C++   +   + P  +CAG+  G  D CQGDSGGPL+C+D + E
Sbjct: 516 ASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAE 575

Query: 186 SACVVVGITSWGVGCARAKRPGIYTATWPYLNWI 219
               + GI SWG GC    +PG+YT    YL WI
Sbjct: 576 RRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAWI 609



 Score = 35.4 bits (80), Expect = 0.078
 Identities = 24/91 (26%), Positives = 32/91 (35%), Gaps = 12/91 (13%)

Query: 263 QPPPRPLPPRPPAAQPRPPPSPPPPPPPPPSPLPPPPP------------PPPPTPSSTT 310
           Q P +  PP P + +   P  P  P PP P P    PP              PP+ +   
Sbjct: 296 QTPTQAAPPTPVSPRLHVPLMPAQPAPPKPQPTTRTPPQSQTPGALPAKREQPPSLTRNG 355

Query: 311 KLPQGLSFAKRLQQLIEVLKGKTYSDGKNHY 341
            L  G    K L  +  V+ G     G + Y
Sbjct: 356 PLSCGQRLRKSLSSMTRVVGGLVALRGAHPY 386



 Score = 32.3 bits (72), Expect = 0.66
 Identities = 26/95 (27%), Positives = 34/95 (35%), Gaps = 10/95 (10%)

Query: 237 PPPTTRPPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPPSPLP 296
           P     P P+ P    PL          P +P PP+P      PP S  P   P     P
Sbjct: 298 PTQAAPPTPVSPRLHVPLM---------PAQPAPPKPQPTTRTPPQSQTPGALPAKREQP 348

Query: 297 PPPPPPPPTPSSTTKLPQGLSFAKRLQQLIEVLKG 331
           P      P  S   +L + LS   R+   +  L+G
Sbjct: 349 PSLTRNGPL-SCGQRLRKSLSSMTRVVGGLVALRG 382


>gi|110815798 ovochymase 1 [Homo sapiens]
          Length = 1134

 Score = 85.9 bits (211), Expect = 5e-17
 Identities = 58/186 (31%), Positives = 91/186 (48%), Gaps = 17/186 (9%)

Query: 95  IPSAAEPRRSEEGQEAGGVAYSQTVGADTPRPSSMLMEARVDLIDLDLCNSTQWYNEH-- 152
           +P +AEP  S E     G     ++ AD    +S L + +V +++ ++C  T +Y+ H  
Sbjct: 685 LPHSAEPLFSSEICAVTGWG---SISADGGL-ASRLQQIQVHVLEREVCEHT-YYSAHPG 739

Query: 153 -VQPTNVCAGYPV-GKIDTCQGDSGGPLMCKDSKESACVVVGITSWGVGCARAKRPGIYT 210
            +    +CAG+   G+ D CQGDSGGPL+C+  +    V+ GI SWG GC +  +PG++ 
Sbjct: 740 GITEKMICAGFAASGEKDFCQGDSGGPLVCRH-ENGPFVLYGIVSWGAGCVQPWKPGVFA 798

Query: 211 ATWPYLNWIASKIG-------SNALRMIQSATPPPPTTRPPPIRPPFSHPLSAHLPWYFQ 263
               +L+WI SKI        +N  + ++   PPP  +      P          P  F 
Sbjct: 799 RVMIFLDWIQSKINGPASLQTNNKCKTLKQQLPPPTPSPDSASWPGCCSEAELEKPRGFF 858

Query: 264 PPPRPL 269
           P PR L
Sbjct: 859 PTPRYL 864



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 39/108 (36%), Positives = 58/108 (53%), Gaps = 7/108 (6%)

Query: 104 SEEGQEAGGVAYSQTVG--ADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQP---TNV 158
           S++  E G +  S   G  + T   S++L E  + ++D   CN T   + ++ P   T +
Sbjct: 163 SDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACN-TVLKSMNLPPLGRTML 221

Query: 159 CAGYPVGKIDTCQGDSGGPLMCKDSKESACVVVGITSWGVGCARAKRP 206
           CAG+P   +D CQGDSGGPL+C+       ++ GITSW  GCA    P
Sbjct: 222 CAGFPDWGMDACQGDSGGPLVCRRG-GGIWILAGITSWVAGCAGGSVP 268


>gi|117956391 protease, serine, 33 [Homo sapiens]
          Length = 280

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 43/101 (42%), Positives = 55/101 (54%), Gaps = 9/101 (8%)

Query: 130 LMEARVDLIDLDLCNSTQWYNEHVQ-------PTNVCAGYPVGKIDTCQGDSGGPLMCKD 182
           L   RV L+D   C+        V        P ++CAGYP G  D CQGDSGGPL C  
Sbjct: 180 LQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQ 239

Query: 183 SKESACVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKI 223
           S   + V+VG+ SWG GCA   RPG+YT+   Y  WI +++
Sbjct: 240 S--GSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARV 278


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 40/99 (40%), Positives = 60/99 (60%), Gaps = 3/99 (3%)

Query: 128 SMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESA 187
           ++L +  + L+  + C   ++ +  +    VCAGY  G  D C+GDSGGPL+CK +    
Sbjct: 533 NILQKVNIPLVTNEECQK-RYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHN--GM 589

Query: 188 CVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSN 226
             +VGITSWG GCAR ++PG+YT    Y++WI  K  S+
Sbjct: 590 WRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSS 628


>gi|4503627 coagulation factor XI precursor [Homo sapiens]
          Length = 625

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 39/93 (41%), Positives = 57/93 (61%), Gaps = 3/93 (3%)

Query: 130 LMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESACV 189
           L +A++ L+  + C   ++    +    +CAGY  G  D C+GDSGGPL CK ++     
Sbjct: 532 LQKAKIPLVTNEECQK-RYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNE--VWH 588

Query: 190 VVGITSWGVGCARAKRPGIYTATWPYLNWIASK 222
           +VGITSWG GCA+ +RPG+YT    Y++WI  K
Sbjct: 589 LVGITSWGEGCAQRERPGVYTNVVEYVDWILEK 621


>gi|11545839 protease, serine, 22 [Homo sapiens]
          Length = 317

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 42/113 (37%), Positives = 61/113 (53%), Gaps = 6/113 (5%)

Query: 120 GADTPRPSSMLMEARVDLIDLDLCNSTQWYNEHVQPTN---VCAGYPVGKIDTCQGDSGG 176
           G   P P + L + +V +ID ++C+   W      P     +CAGY  G+ D C GDSGG
Sbjct: 186 GVPLPHPQT-LQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGG 244

Query: 177 PLMCKDSKESACVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALR 229
           PLMC+   + A ++ GI SWG GCA   RPG+Y +   + +W+   +    LR
Sbjct: 245 PLMCQ--VDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLR 295


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 41/93 (44%), Positives = 53/93 (56%), Gaps = 3/93 (3%)

Query: 127 SSMLMEARVDLIDLDLCNSTQWYNEHVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKES 186
           S+ L +  V LI  DLC+    Y   V P  +CAGY  GK D CQGDSGGPL+CK +   
Sbjct: 717 SNALQKVDVQLIPQDLCSEV--YRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCK-ALSG 773

Query: 187 ACVVVGITSWGVGCARAKRPGIYTATWPYLNWI 219
              + G+ SWG+GC R    G+YT     ++WI
Sbjct: 774 RWFLAGLVSWGLGCGRPNYFGVYTRITGVISWI 806


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,934,990
Number of Sequences: 37866
Number of extensions: 1988806
Number of successful extensions: 133625
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2332
Number of HSP's successfully gapped in prelim test: 886
Number of HSP's that attempted gapping in prelim test: 24473
Number of HSP's gapped (non-prelim): 39574
length of query: 355
length of database: 18,247,518
effective HSP length: 103
effective length of query: 252
effective length of database: 14,347,320
effective search space: 3615524640
effective search space used: 3615524640
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.