Search of human proteins with 110665701

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110665701 leucine rich repeat containing 37A [Homo sapiens]
         (1700 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110665701 leucine rich repeat containing 37A [Homo sapiens]       3442   0.0  
gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]        3421   0.0  
gi|239740953 PREDICTED: similar to c114 SLIT-like testicular pro...  3404   0.0  
gi|239740955 PREDICTED: similar to c114 SLIT-like testicular pro...  3242   0.0  
gi|75677612 leucine rich repeat containing 37, member A3 [Homo s...  3189   0.0  
gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo ...  1747   0.0  
gi|53829385 leucine rich repeat containing 37B [Homo sapiens]         754   0.0  
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                  106   2e-22
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                   106   2e-22
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                  106   2e-22
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                  106   2e-22
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    97   1e-19
gi|224458301 family with sequence similarity 186, member A [Homo...    92   4e-18
gi|91982772 mucin 17 [Homo sapiens]                                    91   7e-18
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              88   8e-17
gi|151301154 mucin 6, gastric [Homo sapiens]                           84   9e-16
gi|116284392 mucin 2 precursor [Homo sapiens]                          84   1e-15
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       84   1e-15
gi|110349719 titin isoform N2-A [Homo sapiens]                         81   1e-14
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             79   3e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    79   4e-14
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        78   6e-14
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    77   1e-13
gi|146134388 YLP motif containing 1 [Homo sapiens]                     77   1e-13
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          76   3e-13
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          76   3e-13
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          76   3e-13
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             75   4e-13
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                        72   5e-12
gi|27881494 zonadhesin isoform 6 [Homo sapiens]                        72   5e-12

>gi|110665701 leucine rich repeat containing 37A [Homo sapiens]
          Length = 1700

 Score = 3442 bits (8925), Expect = 0.0
 Identities = 1700/1700 (100%), Positives = 1700/1700 (100%)

Query: 1    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60
            MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW
Sbjct: 1    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60

Query: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
            SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP
Sbjct: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120

Query: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180
            LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL
Sbjct: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180

Query: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
            QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
            EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
Sbjct: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
            QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
Sbjct: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
            IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
            QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
            QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
            LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
Sbjct: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780

Query: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
            QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
Sbjct: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900
            LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
Sbjct: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900

Query: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960
            LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
Sbjct: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960

Query: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020
            HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL
Sbjct: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020

Query: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080
            PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
Sbjct: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080

Query: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP 1140
            TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP
Sbjct: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP 1140

Query: 1141 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200
            FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
Sbjct: 1141 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200

Query: 1201 AEEKRLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260
            AEEKRLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
Sbjct: 1201 AEEKRLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260

Query: 1261 PAKALPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTK 1320
            PAKALPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTK
Sbjct: 1261 PAKALPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTK 1320

Query: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSALSE 1380
            VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSALSE
Sbjct: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSALSE 1380

Query: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440
            HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
Sbjct: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440

Query: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500
            TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
Sbjct: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500

Query: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560
            LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS
Sbjct: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560

Query: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620
            EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR
Sbjct: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620

Query: 1621 GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDLYKPLSATRINNHAWKLHKKSSNEDKIL 1680
            GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDLYKPLSATRINNHAWKLHKKSSNEDKIL
Sbjct: 1621 GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDLYKPLSATRINNHAWKLHKKSSNEDKIL 1680

Query: 1681 NRDPGDSEAPTEEEESEALP 1700
            NRDPGDSEAPTEEEESEALP
Sbjct: 1681 NRDPGDSEAPTEEEESEALP 1700


>gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]
          Length = 1700

 Score = 3421 bits (8871), Expect = 0.0
 Identities = 1691/1700 (99%), Positives = 1693/1700 (99%)

Query: 1    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60
            MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPP+SW
Sbjct: 1    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSW 60

Query: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
            SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP
Sbjct: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120

Query: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180
            LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL
Sbjct: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180

Query: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
            QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
            EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
Sbjct: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
            QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
Sbjct: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
            IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
            QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
            QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
            LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTET HSTALEKTTAPRPDRV
Sbjct: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRV 780

Query: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
            QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
Sbjct: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900
            LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
Sbjct: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900

Query: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960
            LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
Sbjct: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960

Query: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020
            HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL
Sbjct: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020

Query: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080
            PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
Sbjct: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080

Query: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP 1140
            TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP
Sbjct: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP 1140

Query: 1141 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200
            FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
Sbjct: 1141 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200

Query: 1201 AEEKRLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260
            AEEKRL SPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
Sbjct: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260

Query: 1261 PAKALPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTK 1320
            PAKALPQVRDR KDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRT K
Sbjct: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320

Query: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSALSE 1380
            VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSA SE
Sbjct: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380

Query: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440
            HFIE NNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHP EADSAGTAFNLGPTVKQ
Sbjct: 1381 HFIENNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPHEADSAGTAFNLGPTVKQ 1440

Query: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500
            TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
Sbjct: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500

Query: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560
            LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS
Sbjct: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560

Query: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620
            EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR
Sbjct: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620

Query: 1621 GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDLYKPLSATRINNHAWKLHKKSSNEDKIL 1680
            GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKD+YKPLSATRINNHAWKLHKKSSNEDKIL
Sbjct: 1621 GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDMYKPLSATRINNHAWKLHKKSSNEDKIL 1680

Query: 1681 NRDPGDSEAPTEEEESEALP 1700
            NRDPGDSEAPTEEEESEALP
Sbjct: 1681 NRDPGDSEAPTEEEESEALP 1700


>gi|239740953 PREDICTED: similar to c114 SLIT-like testicular protein
            isoform 2 [Homo sapiens]
          Length = 1700

 Score = 3404 bits (8826), Expect = 0.0
 Identities = 1684/1700 (99%), Positives = 1686/1700 (99%)

Query: 1    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60
            M+SAQCPAL CVMS LRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPE W
Sbjct: 1    MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60

Query: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
            SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGE P
Sbjct: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120

Query: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180
            LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGI RQLSTPQSQKQTL
Sbjct: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTL 180

Query: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
            QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
            EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
Sbjct: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
            QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
Sbjct: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
            IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
            QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
            QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
            LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
Sbjct: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780

Query: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
            QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
Sbjct: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900
            LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
Sbjct: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900

Query: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960
            LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
Sbjct: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960

Query: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020
            HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL
Sbjct: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020

Query: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080
            PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNT HCPEEASVGNPEGAFMKVLQARKNY
Sbjct: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTIHCPEEASVGNPEGAFMKVLQARKNY 1080

Query: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP 1140
            TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTL YILPYFSAVNLDVKSLLLP
Sbjct: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLRYILPYFSAVNLDVKSLLLP 1140

Query: 1141 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200
             IKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
Sbjct: 1141 LIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200

Query: 1201 AEEKRLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260
            AEEKRL SPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
Sbjct: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260

Query: 1261 PAKALPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTK 1320
            PAKALPQVRDR KDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRT K
Sbjct: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320

Query: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSALSE 1380
            VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSA SE
Sbjct: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380

Query: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440
            HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
Sbjct: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440

Query: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500
            TETKWEYNNVGTD SPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
Sbjct: 1441 TETKWEYNNVGTDPSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500

Query: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560
            LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS
Sbjct: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560

Query: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620
            EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR
Sbjct: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620

Query: 1621 GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDLYKPLSATRINNHAWKLHKKSSNEDKIL 1680
            GIFRFLP RGCSSRRESQDGLSSFGQPLWFKD+YKPLSATRINNHAWKLHKKSSNEDKIL
Sbjct: 1621 GIFRFLPRRGCSSRRESQDGLSSFGQPLWFKDMYKPLSATRINNHAWKLHKKSSNEDKIL 1680

Query: 1681 NRDPGDSEAPTEEEESEALP 1700
            NRDPGDSEAPTEEEESEALP
Sbjct: 1681 NRDPGDSEAPTEEEESEALP 1700


>gi|239740955 PREDICTED: similar to c114 SLIT-like testicular protein
            isoform 1 [Homo sapiens]
          Length = 1635

 Score = 3242 bits (8407), Expect = 0.0
 Identities = 1606/1620 (99%), Positives = 1607/1620 (99%)

Query: 1    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60
            M+SAQCPAL CVMS LRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPE W
Sbjct: 1    MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60

Query: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
            SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGE P
Sbjct: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120

Query: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180
            LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGI RQLSTPQSQKQTL
Sbjct: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTL 180

Query: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
            QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
            EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
Sbjct: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
            QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
Sbjct: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
            IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
            QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
            QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
            LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
Sbjct: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780

Query: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
            QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
Sbjct: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900
            LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
Sbjct: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900

Query: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960
            LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
Sbjct: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960

Query: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020
            HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL
Sbjct: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020

Query: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080
            PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNT HCPEEASVGNPEGAFMKVLQARKNY
Sbjct: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTIHCPEEASVGNPEGAFMKVLQARKNY 1080

Query: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP 1140
            TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTL YILPYFSAVNLDVKSLLLP
Sbjct: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLRYILPYFSAVNLDVKSLLLP 1140

Query: 1141 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200
             IKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
Sbjct: 1141 LIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200

Query: 1201 AEEKRLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260
            AEEKRL SPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
Sbjct: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260

Query: 1261 PAKALPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTK 1320
            PAKALPQVRDR KDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRT K
Sbjct: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320

Query: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSALSE 1380
            VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSA SE
Sbjct: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380

Query: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440
            HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
Sbjct: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440

Query: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500
            TETKWEYNNVGTD SPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
Sbjct: 1441 TETKWEYNNVGTDPSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500

Query: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560
            LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS
Sbjct: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560

Query: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620
            EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR
Sbjct: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620



 Score = 35.4 bits (80), Expect = 0.48
 Identities = 19/31 (61%), Positives = 22/31 (70%), Gaps = 2/31 (6%)

Query: 1670 HKKSSNEDKILNRDPGDSEAPTEEEESEALP 1700
            H++S  ED+       DSEAPTEEEESEALP
Sbjct: 1607 HRRSLQEDE--EGFSRDSEAPTEEEESEALP 1635


>gi|75677612 leucine rich repeat containing 37, member A3 [Homo
            sapiens]
          Length = 1634

 Score = 3189 bits (8268), Expect = 0.0
 Identities = 1578/1620 (97%), Positives = 1591/1620 (98%)

Query: 1    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60
            M+SAQCPAL CVMS LRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPE W
Sbjct: 1    MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60

Query: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
            SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGE P
Sbjct: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120

Query: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180
            LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGI  QLSTPQSQKQTL
Sbjct: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTL 180

Query: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
            QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
            EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
Sbjct: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
            QQPVQPSES REVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
Sbjct: 361  QQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
            IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
            QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
            QATVQPLDLGFTITPES TEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541  QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
            LDLELTITTKPTTEVKPSPTTEETSTQ PDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
Sbjct: 721  LDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780

Query: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
            QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
Sbjct: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900
            LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
Sbjct: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900

Query: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960
            LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
Sbjct: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960

Query: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020
            HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLI+
Sbjct: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIV 1020

Query: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080
            PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
Sbjct: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080

Query: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP 1140
            TSTELI+EPEEPSDSSGINLSGFGSEQLDTNDESD  STLSYILPYFSAVNLDVKSLLLP
Sbjct: 1081 TSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLP 1140

Query: 1141 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200
            FIKLPTTGNSLAKIQTVG+NRQR+ RVLMGPRSIQKRHFKEVGRQSIRREQGAQASVEN 
Sbjct: 1141 FIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENT 1200

Query: 1201 AEEKRLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260
            AEEKRL SPAPRE++QPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
Sbjct: 1201 AEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260

Query: 1261 PAKALPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTK 1320
            PAKALPQVRDR KDLTHAISILESAKARVTN KTSKPIVH+RKKYRFHKTRS +THRT K
Sbjct: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPK 1320

Query: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSALSE 1380
            VKKSPKVRKKSYLSRLML+NRLPFSAAKSLINSPSQGAFSSL DLSPQENPFLEVSA SE
Sbjct: 1321 VKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSE 1380

Query: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440
            HFIE NNTK TTARNAFEEN FMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
Sbjct: 1381 HFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440

Query: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500
            TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQS+IPNNNVRRLIAHVIRT
Sbjct: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRT 1500

Query: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560
            LKMDCSGAHVQVTCAKL+SRTGHLMKLLSGQQEVKASKIEWDTDQWK ENYINESTEAQS
Sbjct: 1501 LKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQS 1560

Query: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620
            EQKEKSLE  KE+PGYGYT KLILALIVTGILTILIIL CLI ICCHRRSLQEDEEGFSR
Sbjct: 1561 EQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSR 1620


>gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo
           sapiens]
          Length = 870

 Score = 1747 bits (4525), Expect = 0.0
 Identities = 858/870 (98%), Positives = 859/870 (98%)

Query: 1   MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60
           MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW
Sbjct: 1   MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60

Query: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
           SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP
Sbjct: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120

Query: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180
           LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGI RQLSTPQSQKQTL
Sbjct: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTL 180

Query: 181 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
           QNEYSSTDTPYP SLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181 QNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
           EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
           PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV PMEHELSISEQ
Sbjct: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQ 360

Query: 361 QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
           QQPVQPSES REVESS TQQETPGQPPEHHEVTVSPPGHHQTHHL SPSVSVKPPDVQLT
Sbjct: 361 QQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLT 420

Query: 421 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
           IAAEPSAEVGTSLVHQEAT RLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421 IAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
           QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541 QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
           QATVQPLDLGFTITPES TEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
           PVSPSVTVQLLDLGLTITPEPTTEVGHST PKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
           ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
           LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAP PDRV
Sbjct: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRV 780

Query: 781 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
           Q+LHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEE KASTSTNICELCTCGDEM
Sbjct: 781 QSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEM 840

Query: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870
           LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL
Sbjct: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870


>gi|53829385 leucine rich repeat containing 37B [Homo sapiens]
          Length = 947

 Score =  754 bits (1948), Expect = 0.0
 Identities = 394/570 (69%), Positives = 441/570 (77%), Gaps = 32/570 (5%)

Query: 562  ELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP 621
            EL     E P  P +  + Q  +     NP   +D     +      QLL L   + P  
Sbjct: 240  ELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPS- 298

Query: 622  TTEVGHSTPPKRTIVS----PKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTIT--PK 675
            T +   + PP+ ++ S    P + EVT+  P + Q  H +L + TV+P D+  T+T  PK
Sbjct: 299  TQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQA-HYNLPKFTVKPADVEVTMTSEPK 357

Query: 676  SMTE---------------VEPS-TALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQ 719
            + TE                EPS TAL TT PPP HPEVTLPPSDKGQAQHSHLT+ATVQ
Sbjct: 358  NETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQ 417

Query: 720  PLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDR 779
            PLDLEL+ITT+PTTEVKPSPTTEETS QPPD GLAI PEPTTE GHSTALEKT AP PD+
Sbjct: 418  PLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQ 477

Query: 780  VQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDE 839
            VQTLHRSLTEVTGPPT+LE +QDSLVQSE        TAPEE KASTSTNICELCTCGDE
Sbjct: 478  VQTLHRSLTEVTGPPTKLESSQDSLVQSE--------TAPEEQKASTSTNICELCTCGDE 529

Query: 840  MLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILREN 899
             LSC+ L+P+QRLRQVPVPEP+T+NG FT LNFQGNYISY+DGNVWKAYSWTEKLIL EN
Sbjct: 530  TLSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSEN 589

Query: 900  NLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQA 959
             LTEL KDSFEGLL LQYLDLSCNKI+ IER TFE LPFL++INL CN+IT+LS GTFQA
Sbjct: 590  YLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQA 649

Query: 960  WHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLI 1019
            WHGMQFLH LILN NPLTTVEDPYLF+LPALKYLDMGTT + LTTLKNIL MTVELEKLI
Sbjct: 650  WHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILTMTVELEKLI 709

Query: 1020 LPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKN 1079
            LPSHMACCLCQFKNSIEAVCKTVKLHCN+ACLTN+ HCPEEASVGNPEGAFMK+LQARK 
Sbjct: 710  LPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGAFMKMLQARKQ 769

Query: 1080 YTSTELIVEPEEPSDSSGINLSGFGSEQLD 1109
            + ST+L +E E PSDSSGINLSGFG +QL+
Sbjct: 770  HMSTQLTIESEAPSDSSGINLSGFGGDQLE 799



 Score =  480 bits (1236), Expect = e-135
 Identities = 284/539 (52%), Positives = 327/539 (60%), Gaps = 81/539 (15%)

Query: 13  MSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESWSSHSSHFPRESP 72
           MS LRFWGPWPLL WQLL LLVKEAQPL WVKDPLQLTSNPLGPPE WSS SSH P ESP
Sbjct: 1   MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESP 60

Query: 73  HAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQD 132
           HAP  PA P DFD+LGPSASS+M A PQE TENL PFL   DSAGE PL PE FLA+ QD
Sbjct: 61  HAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQD 120

Query: 133 LKDKLSPQERLPVSPKKLKKD--------PAQRW-------------------------- 158
           L DK +P+ERLP     L +D        P  +W                          
Sbjct: 121 LNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVS 180

Query: 159 --------------------SLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE 198
                               SL EI+GI  QLS PQ QKQTL ++Y S DT YPGSLPPE
Sbjct: 181 RPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPE 240

Query: 199 LRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQ 258
           LRV +DEPPGP EQVG SQFHLEP++QNPETLEDIQSSSLQ+EAPAQL QL +E   S Q
Sbjct: 241 LRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ 300

Query: 259 QEAPALPPESSMESL--TLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNET 316
           QEAPALPPESSMESL  T  NHEV+VQPPGEDQA+Y+LP  TVKPADVEVT+TSEP NET
Sbjct: 301 QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNET 360

Query: 317 ESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQP-----VQPSESPR 371
           ES+QAQQE PIQ PEE EPS+T       PP  P E  L  S++ Q       + +  P 
Sbjct: 361 ESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHP-EVTLPPSDKGQAQHSHLTEATVQPL 419

Query: 372 EVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGT 431
           ++E S T + T        EV  SP          +   S +PPD  L I  EP+ E+G 
Sbjct: 420 DLELSITTEPTT-------EVKPSP---------TTEETSAQPPDPGLAITPEPTTEIGH 463

Query: 432 SLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNEN 490
           S   ++           +     +  GPP   ESS+++    VQ ET+ +  +   + N
Sbjct: 464 STALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDS---LVQSETAPEEQKASTSTN 519



 Score =  176 bits (447), Expect = 1e-43
 Identities = 101/199 (50%), Positives = 133/199 (66%), Gaps = 5/199 (2%)

Query: 1417 TNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSP--GDQFE 1474
            TN  H PE  S G     G  +K  + + ++ +    +  E  S +  +  S   GDQ E
Sbjct: 742  TNSIHCPEEASVGNPE--GAFMKMLQARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLE 799

Query: 1475 IQLTQQLQSLIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEV 1534
            IQLT+QL+SLIPN +VR+ ++HVIRTLKM+CS  HVQ +CAKL+ RTG LMKLLS QQE 
Sbjct: 800  IQLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLMKLLSEQQEA 859

Query: 1535 KASKIEWDTDQWKIENYINESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTI 1594
            KA  +EWDTDQ K  NYINE+ E   ++++KS EL KEVPG  Y +KLI A+ VT IL I
Sbjct: 860  KALNVEWDTDQQK-TNYINENMEQNEQKEQKSSELMKEVPGDDYKNKLIFAISVTVILII 918

Query: 1595 LIILFCLIVICCHRRSLQE 1613
            LII+FCLI +  H+R+ ++
Sbjct: 919  LIIIFCLIEVNSHKRASEK 937



 Score =  116 bits (290), Expect = 2e-25
 Identities = 97/286 (33%), Positives = 124/286 (43%), Gaps = 54/286 (18%)

Query: 447 NDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTA 506
           N  EPP     GPP      E+ G      E   Q+PE + +   S  Q+EA A+  Q  
Sbjct: 244 NADEPP-----GPP------EQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLP 292

Query: 507 EEGESSLTHQEAPAQTPE----------FPNVVVAQPP----EHSHLTQATVQPLDLGFT 552
           +E E S T QEAPA  PE            + V  QPP     H +L + TV+P D+  T
Sbjct: 293 QEVEPS-TQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVT 351

Query: 553 ITPESKTEVELSPTMKETPTQPPKKVVPQ---LRV------YQGVTNPTPGQDQAQHPVS 603
           +T E K E E +   +E P QPP++  P    LR       +  VT P   + QAQH   
Sbjct: 352 MTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHL 411

Query: 604 PSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTL------------------ 645
              TVQ LDL L+IT EPTTEV  S   + T   P  P + +                  
Sbjct: 412 TEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTR 471

Query: 646 -PHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTA 690
            PHPDQVQT H  LT  T  P  L  +      +E  P     +T+
Sbjct: 472 APHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTS 517


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score =  106 bits (265), Expect = 2e-22
 Identities = 182/758 (24%), Positives = 266/758 (35%), Gaps = 101/758 (13%)

Query: 128 ASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITR-----QLSTPQSQKQTLQN 182
           A+ ++L+ KL  ++       + KK P  +  + +  G        +++TP +   T Q+
Sbjct: 148 AANRELQKKLKVKDN---KKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTS--TTQH 202

Query: 183 EYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEA 242
              ST      + P  +  +   PP  S+    +   +  ET   ET E   ++      
Sbjct: 203 NKVSTSPKITTAKP--INPRPSLPPN-SDTSKETSLTVNKET-TVETKETTTTNKQTSTD 258

Query: 243 PAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA 302
             +     +E  S  +  A  L P S + +   P  E + + P         P    +PA
Sbjct: 259 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA 318

Query: 303 DVE------VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP--PVPPMEHE 354
                     TI S PT   E +    ++    P+E  P+ T++ AP  P  P P    E
Sbjct: 319 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 378

Query: 355 -LSISEQQQPVQPSE------------SPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ 401
               + +  P  P E            +P+E   +  ++ TP  P E    T  P     
Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PT 436

Query: 402 THHLASPSVSVK-------------PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGND 448
           T    +P+   K             P +   T   EPS    T+      TT  S     
Sbjct: 437 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPKEPAPTTTKSAPTTT 493

Query: 449 VEPPAIQHGGPPLLPESSEEAGPLAVQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTA 506
            EP        P  P   +E  P   ++   T+ + P P   + P+PT  +  A  P T 
Sbjct: 494 KEPAPTTTKSAPTTP---KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTP 548

Query: 507 EEGESSLTHQEAPAQTPEFPNVVVAQ---PPEHSHLTQATVQPLDLGFTITPESKTEVEL 563
           +E   + T + AP  TP+ P     +   P     LT  T + L       P   T  EL
Sbjct: 549 KEPAPTTTKKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 607

Query: 564 SPTMKETPT----QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITP 619
           +PT  E PT    + P    P+         P P   +   P +P              P
Sbjct: 608 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK------------EP 655

Query: 620 EPTT--EVGHSTPPKRTIVSPKHPEVTLP-HPDQVQTQHSHLTRATVQPLDLGFTITPKS 676
            PTT  E   +TP      + K P  T P  P   +   +     T    D     TPK 
Sbjct: 656 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 715

Query: 677 MTEVEPSTALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKP--T 732
                P     TT   P P  P+ T P + K  A     T     P +L  T T  P  T
Sbjct: 716 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKGPTST 772

Query: 733 TEVKPSPTTEE----TSTQPPDLGLAIIPEPTT-ETGHSTALEKTTAPRPDRVQTLHRSL 787
           T  KP+PTT +    T+ + P       P PTT ET   T  E +T        T+H+S 
Sbjct: 773 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 832

Query: 788 TEVTGPPTELEPAQDSLVQSES-----YTQNKALTAPE 820
            E T P    EP   +L  S        T+  A T PE
Sbjct: 833 DEST-PELSAEPTPKALENSPKEPGVPTTKTPAATKPE 869



 Score = 99.0 bits (245), Expect = 4e-20
 Identities = 171/730 (23%), Positives = 257/730 (35%), Gaps = 127/730 (17%)

Query: 168 RQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227
           +Q ST   +K T   E  S +      L P  +V + +P   +E          P+   P
Sbjct: 253 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-KPTPKAETTTKGPALTTPKEPTP 311

Query: 228 ETLEDIQSSSLQQEAPAQLPQL-------------------LEEEPSSMQQEAPALPPES 268
            T ++  S++ ++  P  +                       E  P++ ++ AP  P E 
Sbjct: 312 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 371

Query: 269 SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA-----DVEVTITSEPTNET--ESSQA 321
           +  +   P    +   P   +     P    KPA     +   T   EPT  T  E +  
Sbjct: 372 APTTTKEPAPTTTKSAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 429

Query: 322 QQETPIQFPEEVEPSATQQEAPIEP----PVPPMEHELSISEQQQPVQPSE-SPREVESS 376
            +E     P+E  P+A ++ AP  P    P  P E   + +++  P  P E +P   +S+
Sbjct: 430 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 489

Query: 377 PTQQETPGQ---------PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA 427
           PT  + P           P E    T   P    T    +P+   KP     T   EP+ 
Sbjct: 490 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-TTPKEPAPTTPKKPAP---TTPKEPAP 545

Query: 428 EVGTSLVHQEATTRLSGSGNDVEP-PAIQHGGPP-------------LLPESSEEAGPLA 473
              T       TT+        EP P       P             L P + E+  P  
Sbjct: 546 T--TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 603

Query: 474 VQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVA 531
            ++   T+ + P P   E P+PT  +AAA  P T +E   +   + AP  TP+ P     
Sbjct: 604 PEELAPTTPEEPTPTTPEEPAPTTPKAAA--PNTPKEPAPTTPKEPAPT-TPKEP--APT 658

Query: 532 QPPEHSHLTQATVQPLDLG--FTITPESKTEVELSPTMKETPTQP----PKKVVPQLRVY 585
            P E +  T     P  L      TP+     EL+PT  + PT      P    P+    
Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK---- 714

Query: 586 QGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTL 645
            G    TP +     P  P+ T          TP+ T       P   T   P  P+   
Sbjct: 715 -GTAPTTPKEPAPTTPKEPAPT----------TPKGTAPTTLKEPAPTTPKKPA-PKELA 762

Query: 646 PHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTT--APPPGHPEVTLPPS 703
           P   +  T  +    A   P +   T TPK      P     TT   PPP   EV+ P  
Sbjct: 763 PTTTKGPTSTTSDKPAPTTPKETAPT-TPKEPAPTTPKKPAPTTPETPPPTTSEVSTP-- 819

Query: 704 DKGQAQHSHLTQATVQPLDLELTITTKPTTEVK-PSPTTEETSTQPPDLGLAIIPE---- 758
                                 T T +PTT  K P  +T E S +P    L   P+    
Sbjct: 820 ----------------------TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 857

Query: 759 PTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTA 818
           PTT+T  +T  E TT  +    +   R+  E T    ++   +++   +E  T++K +TA
Sbjct: 858 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM--TKETATTTEKTTESK-ITA 914

Query: 819 PEEHKASTST 828
                 ST+T
Sbjct: 915 TTTQVTSTTT 924



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 181/819 (22%), Positives = 275/819 (33%), Gaps = 147/819 (17%)

Query: 68   PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFL 127
            P     APT P +P       P+ +   P  P+E          T + A   P EP    
Sbjct: 327  PTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTT-----TKEPAPTTPKEPAPTT 375

Query: 128  ASQQDLKDKLS----PQERLPVSPKK----LKKDPAQRWSLAEIIGITRQLSTPQSQKQT 179
              +       S    P+E  P +PKK      K+PA               +TP+    T
Sbjct: 376  TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--------------TTPKEPTPT 421

Query: 180  LQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQ 239
               E + T      + P E    + + P P+    P+     P+   P T ++   ++ +
Sbjct: 422  TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPKEPAPTTTKEPSPTTPK 479

Query: 240  QEAPA---QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP------------ 284
            + AP      P   +E   +  + AP  P E S  +   P      +P            
Sbjct: 480  EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 539

Query: 285  ---PGEDQAYYHLPNITVKPADVEVTITSEPT----NETESSQAQQETPIQFPEEVEPSA 337
               P         P  T KPA    T   EP      ET  +  ++ TP   PE++ P+ 
Sbjct: 540  PKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTPKKLTPTT-PEKLAPTT 595

Query: 338  TQQEAPIEP----PVPPMEHELSISEQQQPVQPS----ESPREV------ESSPTQQETP 383
             ++ AP  P    P  P E   +  E+  P  P      +P+E       E +PT  + P
Sbjct: 596  PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 655

Query: 384  GQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLS 443
                       +P G   T  L  P+ +         +A   + E  ++   + A T   
Sbjct: 656  APTTPKETAPTTPKGTAPTT-LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714

Query: 444  GSGNDV--EP-PAIQHGGPPLLPESS-----EEAGPLAVQQE-------TSFQSPEPINN 488
            G+      EP P       P  P+ +     +E  P   ++        T+ + P    +
Sbjct: 715  GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 774

Query: 489  ENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLD 548
            + P+PT  +  A  P T +E   +   + AP  TPE P      PP  S ++  T     
Sbjct: 775  DKPAPTTPKETA--PTTPKEPAPTTPKKPAPT-TPETP------PPTTSEVSTPTTTKEP 825

Query: 549  LGFTITPESKT-EVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVT 607
                 +P+  T E+   PT K     P +  VP        T  TP   +      P +T
Sbjct: 826  TTIHKSPDESTPELSAEPTPKALENSPKEPGVP--------TTKTPAATK------PEMT 871

Query: 608  VQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLD 667
                    T   + TTE    T P+ T  +PK  + T    ++  T  S +T  T Q   
Sbjct: 872  --------TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK--TTESKITATTTQVTS 921

Query: 668  LG------FTITPKSMTEVEPSTAL----MTTAPPPGHPEVTLPPSDKGQAQHSHLTQAT 717
                    F IT    T + P        +TT      PE T  P D+  A +S  T   
Sbjct: 922  TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDR--ATNSKATTPK 979

Query: 718  VQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRP 777
             Q          KPT   K   +T++  T P        P P   T     L  T+    
Sbjct: 980  PQ----------KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAE 1029

Query: 778  DRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
              +QT  R          E+ P  +    +E  T +  L
Sbjct: 1030 AMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1068



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 167/760 (21%), Positives = 257/760 (33%), Gaps = 116/760 (15%)

Query: 144 PVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQT---------------LQNEYSSTD 188
           P SP   KK P    +   I   T++   P ++K+T                +N+ SS+ 
Sbjct: 69  PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 128

Query: 189 TPYPGSLPPELRVKSDEPPGPSEQV--------GPSQFHLEPETQNPETLEDIQS----- 235
           +    S     ++KS +    + ++               +  T  P  +++  S     
Sbjct: 129 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG 188

Query: 236 ---------SSLQQEAPAQLPQLLEEEPSSMQQEAPALPPES--SMESLTLPNHEVSVQP 284
                    S+ Q    +  P++   +P + +   P+LPP S  S E+    N E +V+ 
Sbjct: 189 DFKVTTPDTSTTQHNKVSTSPKITTAKPINPR---PSLPPNSDTSKETSLTVNKETTVET 245

Query: 285 PGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQ---------------ETPIQF 329
                      N        E T +++ T   E + A+                ET  + 
Sbjct: 246 KETTTT-----NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 300

Query: 330 PEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSE-SPREVESSPT--QQETPGQP 386
           P    P       P EP     +     + +  P  P E +P   +S+PT  ++  P   
Sbjct: 301 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 360

Query: 387 PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSG 446
            E    T   P    T   A  +    P   +      P     T+      TT    + 
Sbjct: 361 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP 420

Query: 447 NDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTA 506
              + PA     P   P + +E  P      T+ + P P   + P+PT  +  A  P T 
Sbjct: 421 TTPKEPAPTTKEP--APTTPKEPAP------TAPKKPAPTTPKEPAPTTPKEPA--PTTT 470

Query: 507 EEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPT 566
           +E   +   + AP  T   P       P  +     T +      T  P   T  E +PT
Sbjct: 471 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 530

Query: 567 --MKETPTQP--PKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLT-ITPE- 620
              K  PT P  P    P+         P P   +   P +P  T       LT  TPE 
Sbjct: 531 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 590

Query: 621 --PTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKS 676
             PTT  +   +TP +    +P+ P  T P      T  +       +P        P +
Sbjct: 591 LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP-------APTT 643

Query: 677 MTEVEPSTALMTTAPPPGHPEVTLPPSDKGQA-----QHSHLTQATVQPLDLELTITTKP 731
             E  P+T      P P  P+ T P + KG A     + +  T     P +L  T T +P
Sbjct: 644 PKEPAPTT---PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 700

Query: 732 TTEV--KPSPTTEE--TSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSL 787
           T+    KP+PTT +    T P +      P PTT    +    K TAP      TL    
Sbjct: 701 TSTTCDKPAPTTPKGTAPTTPKE------PAPTTPKEPAPTTPKGTAP-----TTLKEPA 749

Query: 788 TEVTGPPTELEPAQDSLVQSESYTQNK-ALTAPEEHKAST 826
                 P   E A  +     S T +K A T P+E   +T
Sbjct: 750 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 789



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 128/617 (20%), Positives = 219/617 (35%), Gaps = 72/617 (11%)

Query: 254 PSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
           P+S      A PP  + +++       S +PP + +    + +  +     E +++    
Sbjct: 69  PTSPPSSKKAPPPSGASQTIKSTTKR-SPKPPNKKKTKKVIESEEITE---EHSVSENQE 124

Query: 314 NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREV 373
           + + SS +   + I+  +  + SA  +E         ++ +L + + ++    + + ++ 
Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRE---------LQKKLKVKDNKK----NRTKKKP 171

Query: 374 ESSPTQQETPGQPPEHHEVTVSPPGHHQTHH---LASPSVSV-KPPDVQLTIAAEPSAEV 429
              P   +  G   ++ +  V+ P    T H     SP ++  KP + + ++        
Sbjct: 172 TPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSK 231

Query: 430 GTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNE 489
            TSL   + TT             ++        + +   G          QS E  + +
Sbjct: 232 ETSLTVNKETT-------------VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 278

Query: 490 NPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPL 547
           + +PT +  A   P  +T  +G +  T +E    TP+ P     + P  + +  A   P 
Sbjct: 279 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 338

Query: 548 DLGFTITPESKTEV-ELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPS 605
           +   T T  + T   E +PT  KE     PK+  P          PT  +     P  P+
Sbjct: 339 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPTTPKEPA 395

Query: 606 VTVQLLDLGLTITPEPTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATV 663
            T           P PTT  E   +TP + T  +PK P  T   P     +    T A  
Sbjct: 396 PTTPK-------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT-APK 447

Query: 664 QPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDL 723
           +P       TPK      P     TT   P       P + K  A  +  +  T      
Sbjct: 448 KPAPT----TPKEPAPTTPKEPAPTTTKEPS------PTTPKEPAPTTTKSAPTTTKEPA 497

Query: 724 ELTITTKPTTEVKPSPTT--EETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQ 781
             T  + PTT  +PSPTT  E   T P +      P PTT    +    K  AP   +  
Sbjct: 498 PTTTKSAPTTPKEPSPTTTKEPAPTTPKE------PAPTTPKKPAPTTPKEPAPTTPKEP 551

Query: 782 TLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEML 841
               + T+   P T  EPA  +  ++   T  K LT     K + +T      T  +E+ 
Sbjct: 552 A--PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKPAPTTPEELA 608

Query: 842 SCIDLNPEQRLRQVPVP 858
                 P     + P P
Sbjct: 609 PTTPEEPTPTTPEEPAP 625



 Score = 37.4 bits (85), Expect = 0.13
 Identities = 27/113 (23%), Positives = 44/113 (38%), Gaps = 4/113 (3%)

Query: 1209 PAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQV 1268
            P   EV  P T + P  +  +   + P  + E         P   G P+T +PA   P++
Sbjct: 811  PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 870

Query: 1269 RDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTKV 1321
               +KD T    +  + +      K +K      +K     T S +T  TT+V
Sbjct: 871  TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK----TTESKITATTTQV 919


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score =  106 bits (265), Expect = 2e-22
 Identities = 182/758 (24%), Positives = 266/758 (35%), Gaps = 101/758 (13%)

Query: 128 ASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITR-----QLSTPQSQKQTLQN 182
           A+ ++L+ KL  ++       + KK P  +  + +  G        +++TP +   T Q+
Sbjct: 189 AANRELQKKLKVKDN---KKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTS--TTQH 243

Query: 183 EYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEA 242
              ST      + P  +  +   PP  S+    +   +  ET   ET E   ++      
Sbjct: 244 NKVSTSPKITTAKP--INPRPSLPPN-SDTSKETSLTVNKET-TVETKETTTTNKQTSTD 299

Query: 243 PAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA 302
             +     +E  S  +  A  L P S + +   P  E + + P         P    +PA
Sbjct: 300 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA 359

Query: 303 DVE------VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP--PVPPMEHE 354
                     TI S PT   E +    ++    P+E  P+ T++ AP  P  P P    E
Sbjct: 360 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 419

Query: 355 -LSISEQQQPVQPSE------------SPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ 401
               + +  P  P E            +P+E   +  ++ TP  P E    T  P     
Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PT 477

Query: 402 THHLASPSVSVK-------------PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGND 448
           T    +P+   K             P +   T   EPS    T+      TT  S     
Sbjct: 478 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPKEPAPTTTKSAPTTT 534

Query: 449 VEPPAIQHGGPPLLPESSEEAGPLAVQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTA 506
            EP        P  P   +E  P   ++   T+ + P P   + P+PT  +  A  P T 
Sbjct: 535 KEPAPTTTKSAPTTP---KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTP 589

Query: 507 EEGESSLTHQEAPAQTPEFPNVVVAQ---PPEHSHLTQATVQPLDLGFTITPESKTEVEL 563
           +E   + T + AP  TP+ P     +   P     LT  T + L       P   T  EL
Sbjct: 590 KEPAPTTTKKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 648

Query: 564 SPTMKETPT----QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITP 619
           +PT  E PT    + P    P+         P P   +   P +P              P
Sbjct: 649 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK------------EP 696

Query: 620 EPTT--EVGHSTPPKRTIVSPKHPEVTLP-HPDQVQTQHSHLTRATVQPLDLGFTITPKS 676
            PTT  E   +TP      + K P  T P  P   +   +     T    D     TPK 
Sbjct: 697 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 756

Query: 677 MTEVEPSTALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKP--T 732
                P     TT   P P  P+ T P + K  A     T     P +L  T T  P  T
Sbjct: 757 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKGPTST 813

Query: 733 TEVKPSPTTEE----TSTQPPDLGLAIIPEPTT-ETGHSTALEKTTAPRPDRVQTLHRSL 787
           T  KP+PTT +    T+ + P       P PTT ET   T  E +T        T+H+S 
Sbjct: 814 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 873

Query: 788 TEVTGPPTELEPAQDSLVQSES-----YTQNKALTAPE 820
            E T P    EP   +L  S        T+  A T PE
Sbjct: 874 DEST-PELSAEPTPKALENSPKEPGVPTTKTPAATKPE 910



 Score = 99.0 bits (245), Expect = 4e-20
 Identities = 171/730 (23%), Positives = 257/730 (35%), Gaps = 127/730 (17%)

Query: 168 RQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227
           +Q ST   +K T   E  S +      L P  +V + +P   +E          P+   P
Sbjct: 294 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-KPTPKAETTTKGPALTTPKEPTP 352

Query: 228 ETLEDIQSSSLQQEAPAQLPQL-------------------LEEEPSSMQQEAPALPPES 268
            T ++  S++ ++  P  +                       E  P++ ++ AP  P E 
Sbjct: 353 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 412

Query: 269 SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA-----DVEVTITSEPTNET--ESSQA 321
           +  +   P    +   P   +     P    KPA     +   T   EPT  T  E +  
Sbjct: 413 APTTTKEPAPTTTKSAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 470

Query: 322 QQETPIQFPEEVEPSATQQEAPIEP----PVPPMEHELSISEQQQPVQPSE-SPREVESS 376
            +E     P+E  P+A ++ AP  P    P  P E   + +++  P  P E +P   +S+
Sbjct: 471 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 530

Query: 377 PTQQETPGQ---------PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA 427
           PT  + P           P E    T   P    T    +P+   KP     T   EP+ 
Sbjct: 531 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-TTPKEPAPTTPKKPAP---TTPKEPAP 586

Query: 428 EVGTSLVHQEATTRLSGSGNDVEP-PAIQHGGPP-------------LLPESSEEAGPLA 473
              T       TT+        EP P       P             L P + E+  P  
Sbjct: 587 T--TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 644

Query: 474 VQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVA 531
            ++   T+ + P P   E P+PT  +AAA  P T +E   +   + AP  TP+ P     
Sbjct: 645 PEELAPTTPEEPTPTTPEEPAPTTPKAAA--PNTPKEPAPTTPKEPAPT-TPKEP--APT 699

Query: 532 QPPEHSHLTQATVQPLDLG--FTITPESKTEVELSPTMKETPTQP----PKKVVPQLRVY 585
            P E +  T     P  L      TP+     EL+PT  + PT      P    P+    
Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK---- 755

Query: 586 QGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTL 645
            G    TP +     P  P+ T          TP+ T       P   T   P  P+   
Sbjct: 756 -GTAPTTPKEPAPTTPKEPAPT----------TPKGTAPTTLKEPAPTTPKKPA-PKELA 803

Query: 646 PHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTT--APPPGHPEVTLPPS 703
           P   +  T  +    A   P +   T TPK      P     TT   PPP   EV+ P  
Sbjct: 804 PTTTKGPTSTTSDKPAPTTPKETAPT-TPKEPAPTTPKKPAPTTPETPPPTTSEVSTP-- 860

Query: 704 DKGQAQHSHLTQATVQPLDLELTITTKPTTEVK-PSPTTEETSTQPPDLGLAIIPE---- 758
                                 T T +PTT  K P  +T E S +P    L   P+    
Sbjct: 861 ----------------------TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 898

Query: 759 PTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTA 818
           PTT+T  +T  E TT  +    +   R+  E T    ++   +++   +E  T++K +TA
Sbjct: 899 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM--TKETATTTEKTTESK-ITA 955

Query: 819 PEEHKASTST 828
                 ST+T
Sbjct: 956 TTTQVTSTTT 965



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 181/819 (22%), Positives = 275/819 (33%), Gaps = 147/819 (17%)

Query: 68   PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFL 127
            P     APT P +P       P+ +   P  P+E          T + A   P EP    
Sbjct: 368  PTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTT-----TKEPAPTTPKEPAPTT 416

Query: 128  ASQQDLKDKLS----PQERLPVSPKK----LKKDPAQRWSLAEIIGITRQLSTPQSQKQT 179
              +       S    P+E  P +PKK      K+PA               +TP+    T
Sbjct: 417  TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--------------TTPKEPTPT 462

Query: 180  LQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQ 239
               E + T      + P E    + + P P+    P+     P+   P T ++   ++ +
Sbjct: 463  TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPKEPAPTTTKEPSPTTPK 520

Query: 240  QEAPA---QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP------------ 284
            + AP      P   +E   +  + AP  P E S  +   P      +P            
Sbjct: 521  EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 580

Query: 285  ---PGEDQAYYHLPNITVKPADVEVTITSEPT----NETESSQAQQETPIQFPEEVEPSA 337
               P         P  T KPA    T   EP      ET  +  ++ TP   PE++ P+ 
Sbjct: 581  PKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTPKKLTPTT-PEKLAPTT 636

Query: 338  TQQEAPIEP----PVPPMEHELSISEQQQPVQPS----ESPREV------ESSPTQQETP 383
             ++ AP  P    P  P E   +  E+  P  P      +P+E       E +PT  + P
Sbjct: 637  PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 696

Query: 384  GQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLS 443
                       +P G   T  L  P+ +         +A   + E  ++   + A T   
Sbjct: 697  APTTPKETAPTTPKGTAPTT-LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755

Query: 444  GSGNDV--EP-PAIQHGGPPLLPESS-----EEAGPLAVQQE-------TSFQSPEPINN 488
            G+      EP P       P  P+ +     +E  P   ++        T+ + P    +
Sbjct: 756  GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 815

Query: 489  ENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLD 548
            + P+PT  +  A  P T +E   +   + AP  TPE P      PP  S ++  T     
Sbjct: 816  DKPAPTTPKETA--PTTPKEPAPTTPKKPAPT-TPETP------PPTTSEVSTPTTTKEP 866

Query: 549  LGFTITPESKT-EVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVT 607
                 +P+  T E+   PT K     P +  VP        T  TP   +      P +T
Sbjct: 867  TTIHKSPDESTPELSAEPTPKALENSPKEPGVP--------TTKTPAATK------PEMT 912

Query: 608  VQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLD 667
                    T   + TTE    T P+ T  +PK  + T    ++  T  S +T  T Q   
Sbjct: 913  --------TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK--TTESKITATTTQVTS 962

Query: 668  LG------FTITPKSMTEVEPSTAL----MTTAPPPGHPEVTLPPSDKGQAQHSHLTQAT 717
                    F IT    T + P        +TT      PE T  P D+  A +S  T   
Sbjct: 963  TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDR--ATNSKATTPK 1020

Query: 718  VQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRP 777
             Q          KPT   K   +T++  T P        P P   T     L  T+    
Sbjct: 1021 PQ----------KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAE 1070

Query: 778  DRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
              +QT  R          E+ P  +    +E  T +  L
Sbjct: 1071 AMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1109



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 167/760 (21%), Positives = 257/760 (33%), Gaps = 116/760 (15%)

Query: 144 PVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQT---------------LQNEYSSTD 188
           P SP   KK P    +   I   T++   P ++K+T                +N+ SS+ 
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 169

Query: 189 TPYPGSLPPELRVKSDEPPGPSEQV--------GPSQFHLEPETQNPETLEDIQS----- 235
           +    S     ++KS +    + ++               +  T  P  +++  S     
Sbjct: 170 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG 229

Query: 236 ---------SSLQQEAPAQLPQLLEEEPSSMQQEAPALPPES--SMESLTLPNHEVSVQP 284
                    S+ Q    +  P++   +P + +   P+LPP S  S E+    N E +V+ 
Sbjct: 230 DFKVTTPDTSTTQHNKVSTSPKITTAKPINPR---PSLPPNSDTSKETSLTVNKETTVET 286

Query: 285 PGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQ---------------ETPIQF 329
                      N        E T +++ T   E + A+                ET  + 
Sbjct: 287 KETTTT-----NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 341

Query: 330 PEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSE-SPREVESSPT--QQETPGQP 386
           P    P       P EP     +     + +  P  P E +P   +S+PT  ++  P   
Sbjct: 342 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 401

Query: 387 PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSG 446
            E    T   P    T   A  +    P   +      P     T+      TT    + 
Sbjct: 402 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP 461

Query: 447 NDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTA 506
              + PA     P   P + +E  P      T+ + P P   + P+PT  +  A  P T 
Sbjct: 462 TTPKEPAPTTKEP--APTTPKEPAP------TAPKKPAPTTPKEPAPTTPKEPA--PTTT 511

Query: 507 EEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPT 566
           +E   +   + AP  T   P       P  +     T +      T  P   T  E +PT
Sbjct: 512 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 571

Query: 567 --MKETPTQP--PKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLT-ITPE- 620
              K  PT P  P    P+         P P   +   P +P  T       LT  TPE 
Sbjct: 572 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 631

Query: 621 --PTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKS 676
             PTT  +   +TP +    +P+ P  T P      T  +       +P        P +
Sbjct: 632 LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP-------APTT 684

Query: 677 MTEVEPSTALMTTAPPPGHPEVTLPPSDKGQA-----QHSHLTQATVQPLDLELTITTKP 731
             E  P+T      P P  P+ T P + KG A     + +  T     P +L  T T +P
Sbjct: 685 PKEPAPTT---PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 741

Query: 732 TTEV--KPSPTTEE--TSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSL 787
           T+    KP+PTT +    T P +      P PTT    +    K TAP      TL    
Sbjct: 742 TSTTCDKPAPTTPKGTAPTTPKE------PAPTTPKEPAPTTPKGTAP-----TTLKEPA 790

Query: 788 TEVTGPPTELEPAQDSLVQSESYTQNK-ALTAPEEHKAST 826
                 P   E A  +     S T +K A T P+E   +T
Sbjct: 791 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 830



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 128/617 (20%), Positives = 219/617 (35%), Gaps = 72/617 (11%)

Query: 254 PSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
           P+S      A PP  + +++       S +PP + +    + +  +     E +++    
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKR-SPKPPNKKKTKKVIESEEITE---EHSVSENQE 165

Query: 314 NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREV 373
           + + SS +   + I+  +  + SA  +E         ++ +L + + ++    + + ++ 
Sbjct: 166 SSSSSSSSSSSSTIRKIKSSKNSAANRE---------LQKKLKVKDNKK----NRTKKKP 212

Query: 374 ESSPTQQETPGQPPEHHEVTVSPPGHHQTHH---LASPSVSV-KPPDVQLTIAAEPSAEV 429
              P   +  G   ++ +  V+ P    T H     SP ++  KP + + ++        
Sbjct: 213 TPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSK 272

Query: 430 GTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNE 489
            TSL   + TT             ++        + +   G          QS E  + +
Sbjct: 273 ETSLTVNKETT-------------VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 319

Query: 490 NPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPL 547
           + +PT +  A   P  +T  +G +  T +E    TP+ P     + P  + +  A   P 
Sbjct: 320 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 379

Query: 548 DLGFTITPESKTEV-ELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPS 605
           +   T T  + T   E +PT  KE     PK+  P          PT  +     P  P+
Sbjct: 380 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPTTPKEPA 436

Query: 606 VTVQLLDLGLTITPEPTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATV 663
            T           P PTT  E   +TP + T  +PK P  T   P     +    T A  
Sbjct: 437 PTTPK-------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT-APK 488

Query: 664 QPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDL 723
           +P       TPK      P     TT   P       P + K  A  +  +  T      
Sbjct: 489 KPAPT----TPKEPAPTTPKEPAPTTTKEPS------PTTPKEPAPTTTKSAPTTTKEPA 538

Query: 724 ELTITTKPTTEVKPSPTT--EETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQ 781
             T  + PTT  +PSPTT  E   T P +      P PTT    +    K  AP   +  
Sbjct: 539 PTTTKSAPTTPKEPSPTTTKEPAPTTPKE------PAPTTPKKPAPTTPKEPAPTTPKEP 592

Query: 782 TLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEML 841
               + T+   P T  EPA  +  ++   T  K LT     K + +T      T  +E+ 
Sbjct: 593 A--PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKPAPTTPEELA 649

Query: 842 SCIDLNPEQRLRQVPVP 858
                 P     + P P
Sbjct: 650 PTTPEEPTPTTPEEPAP 666



 Score = 37.4 bits (85), Expect = 0.13
 Identities = 27/113 (23%), Positives = 44/113 (38%), Gaps = 4/113 (3%)

Query: 1209 PAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQV 1268
            P   EV  P T + P  +  +   + P  + E         P   G P+T +PA   P++
Sbjct: 852  PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 911

Query: 1269 RDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTKV 1321
               +KD T    +  + +      K +K      +K     T S +T  TT+V
Sbjct: 912  TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK----TTESKITATTTQV 960


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score =  106 bits (264), Expect = 2e-22
 Identities = 159/630 (25%), Positives = 219/630 (34%), Gaps = 87/630 (13%)

Query: 251 EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVE----- 305
           +E  S  +  A  L P S + +   P  E + + P         P    +PA        
Sbjct: 174 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 233

Query: 306 -VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP--PVPPMEHE-LSISEQQ 361
             TI S PT   E +    ++    P+E  P+ T++ AP  P  P P    E    + + 
Sbjct: 234 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 293

Query: 362 QPVQPSE------------SPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPS 409
            P  P E            +P+E   +  ++ TP  P E    T  P     T    +P+
Sbjct: 294 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PTTPKEPAPT 351

Query: 410 VSVK-------------PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQH 456
              K             P +   T   EPS    T+      TT  S      EP     
Sbjct: 352 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPKEPAPTTTKSAPTTTKEPAPTTT 408

Query: 457 GGPPLLPESSEEAGPLAVQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLT 514
              P  P   +E  P   ++   T+ + P P   + P+PT  +  A  P T +E   + T
Sbjct: 409 KSAPTTP---KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPAPTTT 463

Query: 515 HQEAPAQTPEFPNVVVAQ---PPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
            + AP  TP+ P     +   P     LT  T + L       P   T  EL+PT  E P
Sbjct: 464 KKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 522

Query: 572 T----QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTT--EV 625
           T    + P    P+         P P   +   P +P              P PTT  E 
Sbjct: 523 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK------------EPAPTTPKET 570

Query: 626 GHSTPPKRTIVSPKHPEVTLP-HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPST 684
             +TP      + K P  T P  P   +   +     T    D     TPK      P  
Sbjct: 571 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 630

Query: 685 ALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKP--TTEVKPSPT 740
              TT   P P  P+ T P + K  A     T     P +L  T T  P  TT  KP+PT
Sbjct: 631 PAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKGPTSTTSDKPAPT 687

Query: 741 TEE----TSTQPPDLGLAIIPEPTT-ETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPT 795
           T +    T+ + P       P PTT ET   T  E +T        T+H+S  E T P  
Sbjct: 688 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST-PEL 746

Query: 796 ELEPAQDSLVQSES-----YTQNKALTAPE 820
             EP   +L  S        T+  A T PE
Sbjct: 747 SAEPTPKALENSPKEPGVPTTKTPAATKPE 776



 Score = 99.0 bits (245), Expect = 4e-20
 Identities = 171/730 (23%), Positives = 257/730 (35%), Gaps = 127/730 (17%)

Query: 168 RQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227
           +Q ST   +K T   E  S +      L P  +V + +P   +E          P+   P
Sbjct: 160 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-KPTPKAETTTKGPALTTPKEPTP 218

Query: 228 ETLEDIQSSSLQQEAPAQLPQL-------------------LEEEPSSMQQEAPALPPES 268
            T ++  S++ ++  P  +                       E  P++ ++ AP  P E 
Sbjct: 219 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 278

Query: 269 SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA-----DVEVTITSEPTNET--ESSQA 321
           +  +   P    +   P   +     P    KPA     +   T   EPT  T  E +  
Sbjct: 279 APTTTKEPAPTTTKSAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 336

Query: 322 QQETPIQFPEEVEPSATQQEAPIEP----PVPPMEHELSISEQQQPVQPSE-SPREVESS 376
            +E     P+E  P+A ++ AP  P    P  P E   + +++  P  P E +P   +S+
Sbjct: 337 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 396

Query: 377 PTQQETPGQ---------PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA 427
           PT  + P           P E    T   P    T    +P+   KP     T   EP+ 
Sbjct: 397 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-TTPKEPAPTTPKKPAP---TTPKEPAP 452

Query: 428 EVGTSLVHQEATTRLSGSGNDVEP-PAIQHGGPP-------------LLPESSEEAGPLA 473
              T       TT+        EP P       P             L P + E+  P  
Sbjct: 453 T--TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 510

Query: 474 VQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVA 531
            ++   T+ + P P   E P+PT  +AAA  P T +E   +   + AP  TP+ P     
Sbjct: 511 PEELAPTTPEEPTPTTPEEPAPTTPKAAA--PNTPKEPAPTTPKEPAPT-TPKEP--APT 565

Query: 532 QPPEHSHLTQATVQPLDLG--FTITPESKTEVELSPTMKETPTQP----PKKVVPQLRVY 585
            P E +  T     P  L      TP+     EL+PT  + PT      P    P+    
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK---- 621

Query: 586 QGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTL 645
            G    TP +     P  P+ T          TP+ T       P   T   P  P+   
Sbjct: 622 -GTAPTTPKEPAPTTPKEPAPT----------TPKGTAPTTLKEPAPTTPKKPA-PKELA 669

Query: 646 PHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTT--APPPGHPEVTLPPS 703
           P   +  T  +    A   P +   T TPK      P     TT   PPP   EV+ P  
Sbjct: 670 PTTTKGPTSTTSDKPAPTTPKETAPT-TPKEPAPTTPKKPAPTTPETPPPTTSEVSTP-- 726

Query: 704 DKGQAQHSHLTQATVQPLDLELTITTKPTTEVK-PSPTTEETSTQPPDLGLAIIPE---- 758
                                 T T +PTT  K P  +T E S +P    L   P+    
Sbjct: 727 ----------------------TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 764

Query: 759 PTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTA 818
           PTT+T  +T  E TT  +    +   R+  E T    ++   +++   +E  T++K +TA
Sbjct: 765 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM--TKETATTTEKTTESK-ITA 821

Query: 819 PEEHKASTST 828
                 ST+T
Sbjct: 822 TTTQVTSTTT 831



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 181/819 (22%), Positives = 275/819 (33%), Gaps = 147/819 (17%)

Query: 68  PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFL 127
           P     APT P +P       P+ +   P  P+E          T + A   P EP    
Sbjct: 234 PTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTT-----TKEPAPTTPKEPAPTT 282

Query: 128 ASQQDLKDKLS----PQERLPVSPKK----LKKDPAQRWSLAEIIGITRQLSTPQSQKQT 179
             +       S    P+E  P +PKK      K+PA               +TP+    T
Sbjct: 283 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--------------TTPKEPTPT 328

Query: 180 LQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQ 239
              E + T      + P E    + + P P+    P+     P+   P T ++   ++ +
Sbjct: 329 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPKEPAPTTTKEPSPTTPK 386

Query: 240 QEAPA---QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP------------ 284
           + AP      P   +E   +  + AP  P E S  +   P      +P            
Sbjct: 387 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 446

Query: 285 ---PGEDQAYYHLPNITVKPADVEVTITSEPT----NETESSQAQQETPIQFPEEVEPSA 337
              P         P  T KPA    T   EP      ET  +  ++ TP   PE++ P+ 
Sbjct: 447 PKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTPKKLTPTT-PEKLAPTT 502

Query: 338 TQQEAPIEP----PVPPMEHELSISEQQQPVQPS----ESPREV------ESSPTQQETP 383
            ++ AP  P    P  P E   +  E+  P  P      +P+E       E +PT  + P
Sbjct: 503 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 562

Query: 384 GQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLS 443
                      +P G   T  L  P+ +         +A   + E  ++   + A T   
Sbjct: 563 APTTPKETAPTTPKGTAPTT-LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 621

Query: 444 GSGNDV--EP-PAIQHGGPPLLPESS-----EEAGPLAVQQE-------TSFQSPEPINN 488
           G+      EP P       P  P+ +     +E  P   ++        T+ + P    +
Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 681

Query: 489 ENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLD 548
           + P+PT  +  A  P T +E   +   + AP  TPE P      PP  S ++  T     
Sbjct: 682 DKPAPTTPKETA--PTTPKEPAPTTPKKPAPT-TPETP------PPTTSEVSTPTTTKEP 732

Query: 549 LGFTITPESKT-EVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVT 607
                +P+  T E+   PT K     P +  VP        T  TP   +      P +T
Sbjct: 733 TTIHKSPDESTPELSAEPTPKALENSPKEPGVP--------TTKTPAATK------PEMT 778

Query: 608 VQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLD 667
                   T   + TTE    T P+ T  +PK  + T    ++  T  S +T  T Q   
Sbjct: 779 --------TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK--TTESKITATTTQVTS 828

Query: 668 LG------FTITPKSMTEVEPSTAL----MTTAPPPGHPEVTLPPSDKGQAQHSHLTQAT 717
                   F IT    T + P        +TT      PE T  P D+  A +S  T   
Sbjct: 829 TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDR--ATNSKATTPK 886

Query: 718 VQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRP 777
            Q          KPT   K   +T++  T P        P P   T     L  T+    
Sbjct: 887 PQ----------KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAE 936

Query: 778 DRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
             +QT  R          E+ P  +    +E  T +  L
Sbjct: 937 AMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 975



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 96/386 (24%), Positives = 138/386 (35%), Gaps = 38/386 (9%)

Query: 481 QSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSH 538
           QS E  + ++ +PT +  A   P  +T  +G +  T +E    TP+ P     + P  + 
Sbjct: 177 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 236

Query: 539 LTQATVQPLDLGFTITPESKTEV-ELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQD 596
           +  A   P +   T T  + T   E +PT  KE     PK+  P          PT  + 
Sbjct: 237 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKS 293

Query: 597 QAQHPVSPSVTVQLLDLGLTITPEPTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQ 654
               P  P+ T           P PTT  E   +TP + T  +PK P  T   P     +
Sbjct: 294 APTTPKEPAPTTPK-------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 346

Query: 655 HSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLT 714
               T A  +P       TPK      P     TT   P       P + K  A  +  +
Sbjct: 347 EPAPT-APKKPAPT----TPKEPAPTTPKEPAPTTTKEPS------PTTPKEPAPTTTKS 395

Query: 715 QATVQPLDLELTITTKPTTEVKPSPTT--EETSTQPPDLGLAIIPEPTTETGHSTALEKT 772
             T        T  + PTT  +PSPTT  E   T P +      P PTT    +    K 
Sbjct: 396 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE------PAPTTPKKPAPTTPKE 449

Query: 773 TAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICE 832
            AP   +      + T+   P T  EPA  +  ++   T  K LT     K + +T    
Sbjct: 450 PAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKP 506

Query: 833 LCTCGDEMLSCIDLNPEQRLRQVPVP 858
             T  +E+       P     + P P
Sbjct: 507 APTTPEELAPTTPEEPTPTTPEEPAP 532



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 53/214 (24%), Positives = 83/214 (38%), Gaps = 14/214 (6%)

Query: 618 TPEPTTEVGH--STPPKRTIVSPKHPEVTLPHPDQVQTQHSHLT---RATVQPLDLGFTI 672
           TP+ +T   +  ST PK T   P +P  +LP P+   ++ + LT     TV+  +   T 
Sbjct: 101 TPDTSTTQHNKVSTSPKITTAKPINPRPSLP-PNSDTSKETSLTVNKETTVETKETTTTN 159

Query: 673 TPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPT 732
              S    E +T+   T          L P+ K  A+ +   + T +   L       PT
Sbjct: 160 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 219

Query: 733 TEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTG 792
           T  +P+ TT +   +P    +   P    E   +T     T P+     T     T+   
Sbjct: 220 TPKEPASTTPK---EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT-----TKEPA 271

Query: 793 PPTELEPAQDSLVQSESYTQNKALTAPEEHKAST 826
           P T  EPA  +  +    T   A T P+E   +T
Sbjct: 272 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 305



 Score = 37.4 bits (85), Expect = 0.13
 Identities = 27/113 (23%), Positives = 44/113 (38%), Gaps = 4/113 (3%)

Query: 1209 PAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQV 1268
            P   EV  P T + P  +  +   + P  + E         P   G P+T +PA   P++
Sbjct: 718  PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 777

Query: 1269 RDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTKV 1321
               +KD T    +  + +      K +K      +K     T S +T  TT+V
Sbjct: 778  TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK----TTESKITATTTQV 826


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score =  106 bits (264), Expect = 2e-22
 Identities = 159/630 (25%), Positives = 219/630 (34%), Gaps = 87/630 (13%)

Query: 251 EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVE----- 305
           +E  S  +  A  L P S + +   P  E + + P         P    +PA        
Sbjct: 215 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 274

Query: 306 -VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP--PVPPMEHE-LSISEQQ 361
             TI S PT   E +    ++    P+E  P+ T++ AP  P  P P    E    + + 
Sbjct: 275 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 334

Query: 362 QPVQPSE------------SPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPS 409
            P  P E            +P+E   +  ++ TP  P E    T  P     T    +P+
Sbjct: 335 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PTTPKEPAPT 392

Query: 410 VSVK-------------PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQH 456
              K             P +   T   EPS    T+      TT  S      EP     
Sbjct: 393 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPKEPAPTTTKSAPTTTKEPAPTTT 449

Query: 457 GGPPLLPESSEEAGPLAVQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLT 514
              P  P   +E  P   ++   T+ + P P   + P+PT  +  A  P T +E   + T
Sbjct: 450 KSAPTTP---KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPAPTTT 504

Query: 515 HQEAPAQTPEFPNVVVAQ---PPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
            + AP  TP+ P     +   P     LT  T + L       P   T  EL+PT  E P
Sbjct: 505 KKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 563

Query: 572 T----QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTT--EV 625
           T    + P    P+         P P   +   P +P              P PTT  E 
Sbjct: 564 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK------------EPAPTTPKET 611

Query: 626 GHSTPPKRTIVSPKHPEVTLP-HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPST 684
             +TP      + K P  T P  P   +   +     T    D     TPK      P  
Sbjct: 612 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 671

Query: 685 ALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKP--TTEVKPSPT 740
              TT   P P  P+ T P + K  A     T     P +L  T T  P  TT  KP+PT
Sbjct: 672 PAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKGPTSTTSDKPAPT 728

Query: 741 TEE----TSTQPPDLGLAIIPEPTT-ETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPT 795
           T +    T+ + P       P PTT ET   T  E +T        T+H+S  E T P  
Sbjct: 729 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST-PEL 787

Query: 796 ELEPAQDSLVQSES-----YTQNKALTAPE 820
             EP   +L  S        T+  A T PE
Sbjct: 788 SAEPTPKALENSPKEPGVPTTKTPAATKPE 817



 Score = 99.0 bits (245), Expect = 4e-20
 Identities = 171/730 (23%), Positives = 257/730 (35%), Gaps = 127/730 (17%)

Query: 168 RQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227
           +Q ST   +K T   E  S +      L P  +V + +P   +E          P+   P
Sbjct: 201 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-KPTPKAETTTKGPALTTPKEPTP 259

Query: 228 ETLEDIQSSSLQQEAPAQLPQL-------------------LEEEPSSMQQEAPALPPES 268
            T ++  S++ ++  P  +                       E  P++ ++ AP  P E 
Sbjct: 260 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 319

Query: 269 SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA-----DVEVTITSEPTNET--ESSQA 321
           +  +   P    +   P   +     P    KPA     +   T   EPT  T  E +  
Sbjct: 320 APTTTKEPAPTTTKSAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 377

Query: 322 QQETPIQFPEEVEPSATQQEAPIEP----PVPPMEHELSISEQQQPVQPSE-SPREVESS 376
            +E     P+E  P+A ++ AP  P    P  P E   + +++  P  P E +P   +S+
Sbjct: 378 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 437

Query: 377 PTQQETPGQ---------PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA 427
           PT  + P           P E    T   P    T    +P+   KP     T   EP+ 
Sbjct: 438 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-TTPKEPAPTTPKKPAP---TTPKEPAP 493

Query: 428 EVGTSLVHQEATTRLSGSGNDVEP-PAIQHGGPP-------------LLPESSEEAGPLA 473
              T       TT+        EP P       P             L P + E+  P  
Sbjct: 494 T--TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 551

Query: 474 VQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVA 531
            ++   T+ + P P   E P+PT  +AAA  P T +E   +   + AP  TP+ P     
Sbjct: 552 PEELAPTTPEEPTPTTPEEPAPTTPKAAA--PNTPKEPAPTTPKEPAPT-TPKEP--APT 606

Query: 532 QPPEHSHLTQATVQPLDLG--FTITPESKTEVELSPTMKETPTQP----PKKVVPQLRVY 585
            P E +  T     P  L      TP+     EL+PT  + PT      P    P+    
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK---- 662

Query: 586 QGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTL 645
            G    TP +     P  P+ T          TP+ T       P   T   P  P+   
Sbjct: 663 -GTAPTTPKEPAPTTPKEPAPT----------TPKGTAPTTLKEPAPTTPKKPA-PKELA 710

Query: 646 PHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTT--APPPGHPEVTLPPS 703
           P   +  T  +    A   P +   T TPK      P     TT   PPP   EV+ P  
Sbjct: 711 PTTTKGPTSTTSDKPAPTTPKETAPT-TPKEPAPTTPKKPAPTTPETPPPTTSEVSTP-- 767

Query: 704 DKGQAQHSHLTQATVQPLDLELTITTKPTTEVK-PSPTTEETSTQPPDLGLAIIPE---- 758
                                 T T +PTT  K P  +T E S +P    L   P+    
Sbjct: 768 ----------------------TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 805

Query: 759 PTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTA 818
           PTT+T  +T  E TT  +    +   R+  E T    ++   +++   +E  T++K +TA
Sbjct: 806 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM--TKETATTTEKTTESK-ITA 862

Query: 819 PEEHKASTST 828
                 ST+T
Sbjct: 863 TTTQVTSTTT 872



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 181/819 (22%), Positives = 275/819 (33%), Gaps = 147/819 (17%)

Query: 68   PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFL 127
            P     APT P +P       P+ +   P  P+E          T + A   P EP    
Sbjct: 275  PTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTT-----TKEPAPTTPKEPAPTT 323

Query: 128  ASQQDLKDKLS----PQERLPVSPKK----LKKDPAQRWSLAEIIGITRQLSTPQSQKQT 179
              +       S    P+E  P +PKK      K+PA               +TP+    T
Sbjct: 324  TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--------------TTPKEPTPT 369

Query: 180  LQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQ 239
               E + T      + P E    + + P P+    P+     P+   P T ++   ++ +
Sbjct: 370  TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPKEPAPTTTKEPSPTTPK 427

Query: 240  QEAPA---QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP------------ 284
            + AP      P   +E   +  + AP  P E S  +   P      +P            
Sbjct: 428  EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 487

Query: 285  ---PGEDQAYYHLPNITVKPADVEVTITSEPT----NETESSQAQQETPIQFPEEVEPSA 337
               P         P  T KPA    T   EP      ET  +  ++ TP   PE++ P+ 
Sbjct: 488  PKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTPKKLTPTT-PEKLAPTT 543

Query: 338  TQQEAPIEP----PVPPMEHELSISEQQQPVQPS----ESPREV------ESSPTQQETP 383
             ++ AP  P    P  P E   +  E+  P  P      +P+E       E +PT  + P
Sbjct: 544  PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 603

Query: 384  GQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLS 443
                       +P G   T  L  P+ +         +A   + E  ++   + A T   
Sbjct: 604  APTTPKETAPTTPKGTAPTT-LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 662

Query: 444  GSGNDV--EP-PAIQHGGPPLLPESS-----EEAGPLAVQQE-------TSFQSPEPINN 488
            G+      EP P       P  P+ +     +E  P   ++        T+ + P    +
Sbjct: 663  GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 722

Query: 489  ENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLD 548
            + P+PT  +  A  P T +E   +   + AP  TPE P      PP  S ++  T     
Sbjct: 723  DKPAPTTPKETA--PTTPKEPAPTTPKKPAPT-TPETP------PPTTSEVSTPTTTKEP 773

Query: 549  LGFTITPESKT-EVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVT 607
                 +P+  T E+   PT K     P +  VP        T  TP   +      P +T
Sbjct: 774  TTIHKSPDESTPELSAEPTPKALENSPKEPGVP--------TTKTPAATK------PEMT 819

Query: 608  VQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLD 667
                    T   + TTE    T P+ T  +PK  + T    ++  T  S +T  T Q   
Sbjct: 820  --------TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK--TTESKITATTTQVTS 869

Query: 668  LG------FTITPKSMTEVEPSTAL----MTTAPPPGHPEVTLPPSDKGQAQHSHLTQAT 717
                    F IT    T + P        +TT      PE T  P D+  A +S  T   
Sbjct: 870  TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDR--ATNSKATTPK 927

Query: 718  VQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRP 777
             Q          KPT   K   +T++  T P        P P   T     L  T+    
Sbjct: 928  PQ----------KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAE 977

Query: 778  DRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
              +QT  R          E+ P  +    +E  T +  L
Sbjct: 978  AMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1016



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 96/386 (24%), Positives = 138/386 (35%), Gaps = 38/386 (9%)

Query: 481 QSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSH 538
           QS E  + ++ +PT +  A   P  +T  +G +  T +E    TP+ P     + P  + 
Sbjct: 218 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 277

Query: 539 LTQATVQPLDLGFTITPESKTEV-ELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQD 596
           +  A   P +   T T  + T   E +PT  KE     PK+  P          PT  + 
Sbjct: 278 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKS 334

Query: 597 QAQHPVSPSVTVQLLDLGLTITPEPTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQ 654
               P  P+ T           P PTT  E   +TP + T  +PK P  T   P     +
Sbjct: 335 APTTPKEPAPTTPK-------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 387

Query: 655 HSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLT 714
               T A  +P       TPK      P     TT   P       P + K  A  +  +
Sbjct: 388 EPAPT-APKKPAPT----TPKEPAPTTPKEPAPTTTKEPS------PTTPKEPAPTTTKS 436

Query: 715 QATVQPLDLELTITTKPTTEVKPSPTT--EETSTQPPDLGLAIIPEPTTETGHSTALEKT 772
             T        T  + PTT  +PSPTT  E   T P +      P PTT    +    K 
Sbjct: 437 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE------PAPTTPKKPAPTTPKE 490

Query: 773 TAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICE 832
            AP   +      + T+   P T  EPA  +  ++   T  K LT     K + +T    
Sbjct: 491 PAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKP 547

Query: 833 LCTCGDEMLSCIDLNPEQRLRQVPVP 858
             T  +E+       P     + P P
Sbjct: 548 APTTPEELAPTTPEEPTPTTPEEPAP 573



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 53/214 (24%), Positives = 83/214 (38%), Gaps = 14/214 (6%)

Query: 618 TPEPTTEVGH--STPPKRTIVSPKHPEVTLPHPDQVQTQHSHLT---RATVQPLDLGFTI 672
           TP+ +T   +  ST PK T   P +P  +LP P+   ++ + LT     TV+  +   T 
Sbjct: 142 TPDTSTTQHNKVSTSPKITTAKPINPRPSLP-PNSDTSKETSLTVNKETTVETKETTTTN 200

Query: 673 TPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPT 732
              S    E +T+   T          L P+ K  A+ +   + T +   L       PT
Sbjct: 201 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 260

Query: 733 TEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTG 792
           T  +P+ TT +   +P    +   P    E   +T     T P+     T     T+   
Sbjct: 261 TPKEPASTTPK---EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT-----TKEPA 312

Query: 793 PPTELEPAQDSLVQSESYTQNKALTAPEEHKAST 826
           P T  EPA  +  +    T   A T P+E   +T
Sbjct: 313 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 346



 Score = 37.4 bits (85), Expect = 0.13
 Identities = 27/113 (23%), Positives = 44/113 (38%), Gaps = 4/113 (3%)

Query: 1209 PAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQV 1268
            P   EV  P T + P  +  +   + P  + E         P   G P+T +PA   P++
Sbjct: 759  PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 818

Query: 1269 RDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTKV 1321
               +KD T    +  + +      K +K      +K     T S +T  TT+V
Sbjct: 819  TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK----TTESKITATTTQV 867


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 187/793 (23%), Positives = 269/793 (33%), Gaps = 123/793 (15%)

Query: 52   NPLGPP--ESWSSHSSHFPRESPHAPTLPADPW-DFDHLG-PSASSEMPAPPQESTENLV 107
            +PL PP  ES +S      R SP    LPA P  +  HL  P   S +  PP+ES  +  
Sbjct: 447  SPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPP 506

Query: 108  PFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQ-ERLPVSPKKLKKDPAQRWSLAEIIGI 166
            P    +    E PL P +       L+  LSP  E  P+SP   ++ P            
Sbjct: 507  PESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPP-FEESP------------ 553

Query: 167  TRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQN 226
               LS P  +               P S PPE    S  P        P +  + P  + 
Sbjct: 554  ---LSPPPEE--------------LPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEA 596

Query: 227  PETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPG 286
                   + S L            EE P S   EA  L P      ++ P  E  + PP 
Sbjct: 597  SRLFPPFEESPLSPPP--------EESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPP 648

Query: 287  EDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEP-SATQQEAPIE 345
            E      LP ++      E +  S P  E+ +S   + + +  P E  P S   +++P  
Sbjct: 649  EVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPAS 708

Query: 346  PPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQP-PEHHEVTVSPPGHHQTHH 404
            P  PP +  +S+  ++ P+ P   P E +  P  +     P PE   ++  P   H +  
Sbjct: 709  P--PPEDSLMSLPLEESPLLP--LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQ 764

Query: 405  LASPSVSVKPPDVQLTIAAE-----PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGP 459
               P +S +P +  L    E     P AE G  L  Q     LS    +          P
Sbjct: 765  AEEPHLSPQPEEPCLCAVPEEPHLSPQAE-GPHLSPQPEELHLSPQTEE----------P 813

Query: 460  PLLPESSEEA-GPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEA 518
             L P   E    P   +   S QS EP  +  P  +      E P  +   E      E 
Sbjct: 814  HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKP---PEE 870

Query: 519  PAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKV 578
            P Q P    + +  PP    L+    +P             E  LSP  +E P  P  + 
Sbjct: 871  PGQCPAPEELPLFPPPGEPSLSPLLGEP-------ALSEPGEPPLSPLPEELPLSPSGE- 922

Query: 579  VPQLRVYQGVTNPTPGQDQAQHPVSPSVTV----QLLDLGLTITP-----EPTTEVGHST 629
             P L       +P P       P+SP +T      L  LG    P     +   E   + 
Sbjct: 923  -PSLSPQLMPPDPLP------PPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAA 975

Query: 630  PPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEP------- 682
            P   T +SP  PE     P+ V           + P   G  + P S   +EP       
Sbjct: 976  PILETPISPP-PEANCTDPEPVPPM--------ILPPSPGSPVGPASPILMEPLPPQCSP 1026

Query: 683  ---STALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSP 739
                + +   +PP       LP S                  +L    T K +    P+ 
Sbjct: 1027 LLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPAL 1086

Query: 740  TTEETSTQPPDLGLAIIPEPT--------TETGHSTA-LEKTTAP--RPDRVQTLHRSLT 788
                TS  P  +G    P P+        +  G  TA L+   AP  +P+  QT     +
Sbjct: 1087 EPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLAS 1146

Query: 789  EVTGPPTELEPAQ 801
            E+ G P  L+P +
Sbjct: 1147 ELKGSPVLLDPEE 1159



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 152/613 (24%), Positives = 233/613 (38%), Gaps = 93/613 (15%)

Query: 183 EYSSTDTPYPGSL-------PPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQS 235
           E   T T  P +L       P    V S +P  P    GP Q   +P  +    LE    
Sbjct: 376 EPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEP----GPLQCEAKPLGKAGVQLEPQLE 431

Query: 236 SSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVS-VQPPGEDQAYYHL 294
           + L +E P   P           +E+P  PP    ES T P  E S + PP E+     L
Sbjct: 432 APLNEEMPLLPPP----------EESPLSPPPE--ESPTSPPPEASRLSPPPEELPASPL 479

Query: 295 PNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPI-----EPPVP 349
           P         E    S P  E+  S   +E+P+  P E  P +  +E+P+      PP P
Sbjct: 480 P---------EALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSP 530

Query: 350 PMEHELSISEQQQPVQP--SESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLAS 407
            +E  LS   +  P+ P   ESP     SP  +E P  PP        PP   ++     
Sbjct: 531 ALETPLSPPPEASPLSPPFEESP----LSPPPEELPTSPPPEASRLSPPP--EESPMSPP 584

Query: 408 PSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSE 467
           P  S   P  + +    P  E   S   +E+        + + PP       P+ P   E
Sbjct: 585 PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPP---EDSPMSPPPEE 641

Query: 468 EAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTA------EEGESSLTHQEAPAQ 521
              P++   E S  SP P+ +    P ++   +  P+ +      E    S   +++P  
Sbjct: 642 --SPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS 699

Query: 522 TPEFPNVVVAQPPEHS----HLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKK 577
            P   +   + PPE S     L ++ + PL     + P S+    LSP  +E P   P+ 
Sbjct: 700 PPP-EDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGP-HLSPRPEE-PHLSPRP 756

Query: 578 VVPQLRVYQGVTNPTPGQDQ---AQHPVSPSVTVQLLDLGLTITPE-----PTTEVGHST 629
             P L       + +P  ++      P  P ++ Q     L+  PE     P TE  H +
Sbjct: 757 EEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLS 816

Query: 630 P-PKRTIVSPKHPEVTL-PHPDQ----VQTQHSHLTRATVQPLDLGFTITPKSMTEVE-- 681
           P P+   +SP+  E  L P  ++     + + SHL+    +P      ++P+     E  
Sbjct: 817 PVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKP-----PLSPRPEKPPEEP 871

Query: 682 ---PSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPS 738
              P+   +   PPPG P  +L P   G+   S   +  + PL  EL ++  P+ E   S
Sbjct: 872 GQCPAPEELPLFPPPGEP--SLSPL-LGEPALSEPGEPPLSPLPEELPLS--PSGEPSLS 926

Query: 739 PTTEETSTQPPDL 751
           P        PP L
Sbjct: 927 PQLMPPDPLPPPL 939



 Score = 67.8 bits (164), Expect = 9e-11
 Identities = 99/427 (23%), Positives = 149/427 (34%), Gaps = 78/427 (18%)

Query: 356 SISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTV--SPPGHHQTHHLASPSVSVK 413
           S++EQ  PV    SP      P   +TP   P+   V     P G H T      S+  K
Sbjct: 360 SVAEQHTPVCSRFSP------PEPGDTPTDEPDALYVACQGQPKGGHVT------SMQPK 407

Query: 414 PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLA 473
            P   L   A+P  + G  L  Q            +E P  +    PLLP   E   PL+
Sbjct: 408 EPG-PLQCEAKPLGKAGVQLEPQ------------LEAPLNEE--MPLLPPPEE--SPLS 450

Query: 474 VQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTP--EFPNVVVA 531
              E S  SP P  +    P ++  A+  P+       S   +E+P   P  E P   ++
Sbjct: 451 PPPEESPTSPPPEASRLSPPPEELPASPLPEAL---HLSRPLEESPLSPPPEESP---LS 504

Query: 532 QPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNP 591
            PPE S  +     PL       P    E  LSP  + +P  PP +  P         +P
Sbjct: 505 PPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESP--------LSP 556

Query: 592 TPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQV 651
            P     + P SP      L                S PP+ + +SP   E  +  P + 
Sbjct: 557 PP----EELPTSPPPEASRL----------------SPPPEESPMSPPPEESPMSPPPEA 596

Query: 652 QTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHS 711
                    + + P        P   + + P       +PPP    ++ PP +   +   
Sbjct: 597 SRLFPPFEESPLSP--------PPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPP 648

Query: 712 HLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEK 771
            +++ +  P+   L   + P  E   SP  EE+ T PP     + P P          + 
Sbjct: 649 EVSRLSPLPVVSRL---SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS 705

Query: 772 TTAPRPD 778
             +P P+
Sbjct: 706 PASPPPE 712



 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 140/674 (20%), Positives = 216/674 (32%), Gaps = 109/674 (16%)

Query: 87   LGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP-LEPEQFLASQQDLKDKLSPQ---ER 142
            LGP     MP  P      LV  L      G Q  L P Q    QQ     L PQ    +
Sbjct: 3769 LGPKPQGLMP--PSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQ 3826

Query: 143  LPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVK 202
            + ++  ++   P        ++G   +L T Q Q+Q  Q++   +       L   L   
Sbjct: 3827 VLMTQSRVLSSPQLAQQGQGLMG--HRLVTAQQQQQQQQHQQQGSMAGL-SHLQQSLMSH 3883

Query: 203  SDEPPGPSEQVGP---------------------SQFHLEPETQNPETLEDIQSSSLQQE 241
            S +P   ++ +G                       Q   + + Q  +  +  Q   LQQ+
Sbjct: 3884 SGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQ 3943

Query: 242  APAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHL--PNITV 299
               QL Q  ++     QQ+      +   + + L N   ++  P + Q       P +  
Sbjct: 3944 QQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPA 4003

Query: 300  KPAD-VEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPI-------EPPVPPM 351
            KP           PT      +     P    E  E  +T Q  P+            P 
Sbjct: 4004 KPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPG 4063

Query: 352  EHELSISEQQQPV----QPSESPREVESSPTQQETPGQPPEHHEV--TVSPPGHHQTHHL 405
            E + S+S   Q +    QP   P  ++  P  +  PGQ  +   +  T     H Q    
Sbjct: 4064 EVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLR-LPGQQQQQVSLLHTAGGGSHGQLGSG 4122

Query: 406  ASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGND-VEPPAIQHGGP----- 459
            +S   S  P      + A+PS  +G        T  L G     +E P   + GP     
Sbjct: 4123 SSSEASSVP-----HLLAQPSVSLGDQ--PGSMTQNLLGPQQPMLERPMQNNTGPQPPKP 4175

Query: 460  -PLLPESS--------EEAGPLAVQQETSFQSPEPINNENPSPTQQEAA---AEHPQTAE 507
             P+L               G L  Q +        + + +P   QQ  A       Q ++
Sbjct: 4176 GPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQ 4235

Query: 508  EGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTM 567
                +  +QE   QT     ++  QP         T    +LG    P+    +   P  
Sbjct: 4236 AVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGA 4295

Query: 568  KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGH 627
              T         P L    G  +PTP     Q P  PS   QL        P P++++  
Sbjct: 4296 LSTG--------PVL----GPVHPTPPPSSPQEPKRPS---QL--------PSPSSQL-- 4330

Query: 628  STPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALM 687
               P    + P HP    P    ++     ++ A  Q  D   T+  K +   +P   L 
Sbjct: 4331 ---PTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLAD---TLFSKGLGPWDPPDNLA 4384

Query: 688  TTAPP------PGH 695
             T  P      PGH
Sbjct: 4385 ETQKPEQSSLVPGH 4398



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 175/803 (21%), Positives = 249/803 (31%), Gaps = 138/803 (17%)

Query: 81   PWDFDHLGPSASSEMPAPPQESTENLVPFLDTW----------DSAGEQPLEPEQFLASQ 130
            P +F    P      P+ P    +   P LD              A E  L P  F  S+
Sbjct: 2223 PGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESR 2282

Query: 131  QDLKDKLSPQERLPVS-----PKKLK--KDPAQRWSLAEIIGITRQLSTPQSQKQTLQNE 183
            + L+ K   +E L  S     P  L     P+    L  +     +L TP   K  L   
Sbjct: 2283 KALEVK---KEELGASSPSYGPPNLGFVDSPSSGTHLGGL-----ELKTPDVFKAPLTPR 2334

Query: 184  YSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAP 243
             S  +   PG     L ++  EPP P++ + PS          P +  DI       +  
Sbjct: 2335 ASQVEPQSPG-----LGLRPQEPP-PAQALAPS----------PPSHPDIFRPGSYTDPY 2378

Query: 244  AQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPAD 303
            AQ P     +P    +   ALPP S      LP+   S  P            +T +P  
Sbjct: 2379 AQPPLTPRPQPPP-PESCCALPPRS------LPSDPFSRVPASPQSQSSSQSPLTPRPLS 2431

Query: 304  VEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSIS----- 358
             E    S  T   +S       P +      P +    AP+  P  P   E++       
Sbjct: 2432 AEAFCPSPVTPRFQSPDPYSRPPSR------PQSRDPFAPLHKPPRPQPPEVAFKAGSLA 2485

Query: 359  -------------------EQQQPVQPSESPREVES----------SPTQQETP---GQP 386
                               E    V   + P  V S          SP +   P   G+P
Sbjct: 2486 HTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEP 2545

Query: 387  PEHHEVTVS--PPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSG 444
                 V     PP H    H        KP     T+A       G+ L     +T  S 
Sbjct: 2546 SLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESY 2605

Query: 445  SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP-EPINNENPSPTQQEAAAEHP 503
              + + PP++    PP  P+ S         Q +   SP E   +         A AE P
Sbjct: 2606 GLSPLRPPSVL---PPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELP 2662

Query: 504  QTAEEGESSL--THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEV 561
             T + G S L  T  E   Q      +++ Q  + + L Q           + P      
Sbjct: 2663 GTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGA 2722

Query: 562  E-LSPTMK-----ETP---TQPPKKVV--PQLRVYQGVTNP--TPGQDQAQHPVSPSVTV 608
            E  SP  +     +TP   TQ    +V  P  ++   +  P   P  D+   P  P  T 
Sbjct: 2723 EPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRP-PPPATP 2781

Query: 609  QLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQ--PL 666
              +D+           VG S    +   +P    + L    Q   Q    T AT     +
Sbjct: 2782 SSMDV------NSRQLVGGSQAFYQR--APYPGSLPLQQQQQQLWQQQQATAATSMRFAM 2833

Query: 667  DLGFTITP----KSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLD 722
               F  TP           P   + T  P PG P     P   G AQ   L     + L 
Sbjct: 2834 SARFPSTPGPELGRQALGSPLAGISTRLPGPGEP----VPGPAGPAQFIELRHNVQKGLG 2889

Query: 723  LELTITTKPTTEVKPS--PTTEETSTQPPD--LGLAI--IPEPTTETGHSTALEKTTAPR 776
               T         +P   P +E+     P+   GLA+  +P        +  L  +  P 
Sbjct: 2890 PGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPT 2949

Query: 777  P-DRVQTLHRSLTEVTGPPTELE 798
            P  +  TL   L  V  PP+  E
Sbjct: 2950 PHTKGPTLPTGLELVNRPPSSTE 2972



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 70/286 (24%), Positives = 100/286 (34%), Gaps = 36/286 (12%)

Query: 503  PQTAEEGESSLTHQEAPAQT--PEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTE 560
            PQ   +  S      APA    P FP      PP  S  T A  QP  LG +  P +   
Sbjct: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSP-TGAPAQPPMLGASSRPGAGQP 2223

Query: 561  VELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPE 620
             E   T   TP   P    P L+         P  D    P SP V        L ++P 
Sbjct: 2224 GEFHTTPPGTPRHQPSTPDPFLKPR------CPSLDNLAVPESPGVGGGKASEPL-LSPP 2276

Query: 621  PTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHS--HLTRATVQPLDL-GFTITPKSM 677
            P  E   +   K+  +    P    P+   V +  S  HL    ++  D+    +TP++ 
Sbjct: 2277 PFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA- 2335

Query: 678  TEVEPSTALMTTAP------------PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLEL 725
            ++VEP +  +   P            PP HP++  P S         LT     P     
Sbjct: 2336 SQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESC 2395

Query: 726  ------TITTKPTTEVKPSPTTEETSTQP----PDLGLAIIPEPTT 761
                  ++ + P + V  SP ++ +S  P    P    A  P P T
Sbjct: 2396 CALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVT 2441



 Score = 39.3 bits (90), Expect = 0.033
 Identities = 114/611 (18%), Positives = 208/611 (34%), Gaps = 112/611 (18%)

Query: 221  EPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQ----EAPALPPESSMESLTLP 276
            + + Q  +  +  Q S++   +P+Q P+LL + P  +      + P  PP      L L 
Sbjct: 3599 QQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLT 3658

Query: 277  NHEVSV--QPPG--------EDQAYYHL---------------PNITVKPADVEVTITSE 311
               +++  QP G        + Q   H                 N+ ++    +  +  E
Sbjct: 3659 PGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQE 3718

Query: 312  P-----------TNETESSQAQQETPIQFPEEVEPSATQQEAP-------IEPP----VP 349
                          + +  Q QQ+       +V     QQ+ P       + P     +P
Sbjct: 3719 RQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMP 3778

Query: 350  PMEHELSISEQQQPVQPSESPR----EVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHL 405
            P  H+  + +Q  P QP + P+      + +  QQ+ PG         + P G H+   +
Sbjct: 3779 PSSHQGLLVQQLSP-QPPQGPQGMLGPAQVAVLQQQHPG--------ALGPQGPHRQVLM 3829

Query: 406  ASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSG---NDVEPPAIQHGGPPLL 462
                V   P   Q          V      Q+   +  GS    + ++   + H G P L
Sbjct: 3830 TQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKL 3889

Query: 463  PESSEEAGPL-AVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQ 521
              S++  G L  +QQ+   Q  + +  +     QQ+   +  Q  ++ +     Q+   Q
Sbjct: 3890 --SAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQ 3947

Query: 522  TPEFPNVVVAQPPEHSHLTQATVQPLDLGF------TITP--ESKTEVELSPTMKETPTQ 573
              +    +  Q  +     Q   Q   +G        ++P  + + +V L P M   P Q
Sbjct: 3948 LQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQ 4007

Query: 574  ---PPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGH--- 627
                P  + P L +            + Q+ V P+V+ +        T  P+T  G    
Sbjct: 4008 HFSSPGALGPTLLL----------TGKEQNTVDPAVSSE-------ATEGPSTHQGGPLA 4050

Query: 628  -STPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITP--KSMTEVEPST 684
              T P+     P   + +L    Q+      L +   QP      + P  +   + +   
Sbjct: 4051 IGTTPESMATEPGEVKPSLSGDSQLL-----LVQPQPQPQPSSLQLQPPLRLPGQQQQQV 4105

Query: 685  ALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTK---PTTEVKPSPTT 741
            +L+ TA    H ++    S +  +    L Q +V   D   ++T     P   +   P  
Sbjct: 4106 SLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQ 4165

Query: 742  EETSTQPPDLG 752
              T  QPP  G
Sbjct: 4166 NNTGPQPPKPG 4176



 Score = 38.9 bits (89), Expect = 0.043
 Identities = 118/542 (21%), Positives = 173/542 (31%), Gaps = 116/542 (21%)

Query: 187  TDTPYPG-----SLPPELRVKSDEPPGPSEQVGPSQFHLEP------ETQNPETLEDIQS 235
            T  PYP      + PP L   S   PG  +   P +FH  P      +   P+     + 
Sbjct: 2195 TYPPYPSPTGAPAQPPMLGASSR--PGAGQ---PGEFHTTPPGTPRHQPSTPDPFLKPRC 2249

Query: 236  SSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLP 295
             SL   A  + P +   + S      P  P   S ++L +   E+    P      Y  P
Sbjct: 2250 PSLDNLAVPESPGVGGGKASEPLLSPP--PFGESRKALEVKKEELGASSPS-----YGPP 2302

Query: 296  NITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHEL 355
            N+              P++ T     + +TP  F   + P A+Q    +EP         
Sbjct: 2303 NLG---------FVDSPSSGTHLGGLELKTPDVFKAPLTPRASQ----VEP--------- 2340

Query: 356  SISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGH-------HQTHHLASP 408
                                SP     P +PP    +  SPP H         T   A P
Sbjct: 2341 -------------------QSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQP 2381

Query: 409  SVSVK--PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESS 466
             ++ +  PP  +   A  P +          A+ +   S      P          P S+
Sbjct: 2382 PLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPR---------PLSA 2432

Query: 467  EEAGPLAVQQETSFQSPEPINNENPSPTQQEAAA-----EHPQTAEEG--ESSLTHQEA- 518
            E   P  V     FQSP+P +     P  ++  A       PQ  E      SL H    
Sbjct: 2433 EAFCPSPVTPR--FQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLG 2490

Query: 519  ----PAQTPEFP------NVVVAQPPE--HSHLTQATV-QPLDLGFTITPESKTEVELSP 565
                PA  P  P       V   QPP    S  T A V  P  + FT  P++  E  L P
Sbjct: 2491 AGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTF-PQAVGEPSLKP 2549

Query: 566  TMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP-TTE 624
             + +    PP  +            P P   + Q       T      G  + P   +T 
Sbjct: 2550 PVPQPGLPPPHGINSHF-------GPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTG 2602

Query: 625  VGHSTPPKR--TIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEP 682
              +   P R  +++ P  P+ +LP+     +Q S +T    +  D G  +     T   P
Sbjct: 2603 ESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELP 2662

Query: 683  ST 684
             T
Sbjct: 2663 GT 2664



 Score = 35.4 bits (80), Expect = 0.48
 Identities = 120/551 (21%), Positives = 191/551 (34%), Gaps = 124/551 (22%)

Query: 114  DSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTP 173
            D+A  +PL P+         K      +RL  S KKL+K+   R S A +  + ++LS  
Sbjct: 4511 DAAARKPLTPKP--------KRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLL 4562

Query: 174  QSQKQTLQNEYSSTDTPYPGSLP----PELRVKSDEPPGPSEQVGPSQFHLEPETQNPET 229
               +  +   + S   P+    P     +LR        P+     SQ   +    NP T
Sbjct: 4563 PLTEPAITANF-SLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPT 4621

Query: 230  LEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP----P 285
                         P+ LP      P S+QQ+         M +   P+ E+   P     
Sbjct: 4622 ------------PPSSLP---PTPPPSVQQK---------MVNGVTPSEELGEHPKDAAS 4657

Query: 286  GEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQ-----Q 340
              D          VK  D+   + + P N+TE  + + +     P+ + P+++      +
Sbjct: 4658 ARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGE 4717

Query: 341  EAPIEP---------------PVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQ 385
            EAP  P               PV P+    SI     PV P   P          E PG+
Sbjct: 4718 EAPRFPHLGSGRWEQEDRALSPVIPLIPRASI-----PVFPDTKP----YGALGLEVPGK 4768

Query: 386  PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL--VHQEATTRLS 443
             P    VT    G           VS     V LT++A  +  +   +  V +  + ++ 
Sbjct: 4769 LP----VTTWEKG-------KGSEVS-----VMLTVSAAAAKNLNGVMVAVAELLSMKIP 4812

Query: 444  GSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHP 503
             S   + P +    G    P+  E  GP   ++    +SP+      P   +Q  A    
Sbjct: 4813 NSYEVLFPESPARAGTE--PKKGEAEGPGGKEKGLEGKSPD----TGPDWLKQFDAVLPG 4866

Query: 504  QTAEEGES--SLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEV 561
             T +      SL  QE+PA  P         P +HS+     V  LD+     P  +   
Sbjct: 4867 YTLKSQLDILSLLKQESPAPEP---------PTQHSY--TYNVSNLDVRQLSAPPPEEPS 4915

Query: 562  ELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP 621
                 +  +P  PP + + +L          P +  A+ PV PS       L L  +PE 
Sbjct: 4916 PPPSPLAPSPASPPTEPLVEL----------PTEPLAEPPV-PS------PLPLASSPES 4958

Query: 622  TTEVGHSTPPK 632
                  + PP+
Sbjct: 4959 ARPKPRARPPE 4969



 Score = 32.0 bits (71), Expect = 5.3
 Identities = 42/147 (28%), Positives = 60/147 (40%), Gaps = 26/147 (17%)

Query: 692 PPGHPEVTLPPSDKG--QAQHSHLTQATVQ-------PLDLELTITTKPTTEVKPSPTTE 742
           P G    ++ P + G  Q +   L +A VQ       PL+ E+ +   P  E   SP  E
Sbjct: 396 PKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPE-ESPLSPPPE 454

Query: 743 ETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTE--VTGPPTE--LE 798
           E+ T PP     + P P          E   +P P+ +  L R L E  ++ PP E  L 
Sbjct: 455 ESPTSPPPEASRLSPPPE---------ELPASPLPEALH-LSRPLEESPLSPPPEESPLS 504

Query: 799 PAQDSLVQSESYTQNKALTAPEEHKAS 825
           P  +S     S  +   L+ PEE   S
Sbjct: 505 PPPES--SPFSPLEESPLSPPEESPPS 529



 Score = 31.2 bits (69), Expect = 9.0
 Identities = 34/145 (23%), Positives = 55/145 (37%), Gaps = 13/145 (8%)

Query: 234  QSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSV-QPPGEDQAYY 292
            +   L+ ++P   P  L++  + +    P    +S ++ L+L   E    +PP +    Y
Sbjct: 4841 KEKGLEGKSPDTGPDWLKQFDAVL----PGYTLKSQLDILSLLKQESPAPEPPTQHSYTY 4896

Query: 293  HLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPI-EPPVPPM 351
            ++ N+ V+         S P  E  S       P       EP       P+ EPPVP  
Sbjct: 4897 NVSNLDVRQL-------SAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSP 4949

Query: 352  EHELSISEQQQPVQPSESPREVESS 376
                S  E  +P   +  P E E S
Sbjct: 4950 LPLASSPESARPKPRARPPEEGEDS 4974


>gi|224458301 family with sequence similarity 186, member A [Homo
            sapiens]
          Length = 2351

 Score = 92.0 bits (227), Expect = 4e-18
 Identities = 175/801 (21%), Positives = 295/801 (36%), Gaps = 134/801 (16%)

Query: 86   HLGPSASSEM---PAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQER 142
            HLGP    E       P+   E+L   + T D    +  +P++         +K+  Q  
Sbjct: 955  HLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKEL--------EKMVIQTP 1006

Query: 143  LPVSP--KKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQ-NEYSSTDTPYPGSLP--- 196
            + +SP  K + KD  + +   E     + L     +K+ +      S     PG+LP   
Sbjct: 1007 MTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEKEPISITPPPSLQYSLPGALPISG 1066

Query: 197  PELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSS 256
              L       P  +++VG +    + + Q   TL   Q+  L      Q  Q LE   + 
Sbjct: 1067 QPLTKCIHLTPQQAQEVGITLTPQQAQAQGI-TLTLQQAQELGIPLTPQQAQALEILFTP 1125

Query: 257  MQQEA---PALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
             Q +A   P  P ++ ++ +TL         P +DQA    P I++              
Sbjct: 1126 QQAQALGIPLTPQQTQVQGITLT--------PQQDQA----PGISL-------------- 1159

Query: 314  NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPME-HELSISEQQQPVQPSESPR- 371
                ++Q  Q+  I       P   QQ   +  P+ P +  EL I     P+ P ++   
Sbjct: 1160 ----TTQQAQKLGI-------PLTPQQAQALGIPLTPQQAQELGI-----PLTPQQAQAL 1203

Query: 372  EVESSPTQQETPGQP--PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEV 429
             V  +P Q +  G P  P+  +         Q   L  P    +   + +T+  +   E+
Sbjct: 1204 RVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQVQEL 1263

Query: 430  GTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAG-PLAVQQETSFQSPEPINN 488
            G  L  Q+A       G  + P   Q  G PL P+ ++  G PL  +Q  +   P     
Sbjct: 1264 GIPLTPQQA----QALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPF---- 1315

Query: 489  ENPSPTQQEAAAEHPQTAEEGESSLTHQEA-----PAQTPEFPNVVVAQPPEHSH---LT 540
              P   Q       PQ A+  E +LT Q+A     P  T +   + +   P+H+    + 
Sbjct: 1316 -TPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMP 1374

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKE--------TPTQPPKKVVPQLRVYQGVTNPT 592
              T Q  +LG  +TP+    + +  T ++        TP Q  +  +P           T
Sbjct: 1375 LTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEIT 1434

Query: 593  PGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRT------IVSPKHPEVTLP 646
                QAQ    P    Q  +LG+T+TP+   E+G    P++       ++ P+  E+ +P
Sbjct: 1435 LTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQAQELGIP 1494

Query: 647  HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKG 706
               Q Q Q   +     Q  +LG  +TP      + + AL     PP   E+ +P     
Sbjct: 1495 LTPQ-QAQALGILLIPPQAQELGIPLTP------QQAQALGIPLIPPQAQELGIP----- 1542

Query: 707  QAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEE------TSTQPPDLGLAIIPEPT 760
                  LT   VQ L + L        E+  +P   +      T  Q  +LG+ + P+  
Sbjct: 1543 ------LTPQQVQALGIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQA 1596

Query: 761  TETGHSTALEKTTAP----RPDRVQTLHRSLTE-------VTGPPTELEPAQDSLVQSES 809
             E G     ++  A      P + Q L  SLT        +T  P + +     +    +
Sbjct: 1597 QELGIPLTPQQAQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQAQALGVPITPVNA 1656

Query: 810  YTQNKALTAPEEHKASTSTNI 830
            +     LT+ + H   +  N+
Sbjct: 1657 WVSAVTLTSEQTHALESPMNL 1677


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 91.3 bits (225), Expect = 7e-18
 Identities = 171/801 (21%), Positives = 291/801 (36%), Gaps = 100/801 (12%)

Query: 58  ESWSSHSSHFPR--ESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDS 115
           ES S  ++ FP   E   +PT P                M  P +ES  + + F+ T   
Sbjct: 120 ESTSDSTTLFPSSTEDTSSPTTPE----------GTDVPMSTPSEESISSTMAFVST--- 166

Query: 116 AGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQS 175
           A     E    L  + D+   L+   +   SP   +     + + +E  G T   S P S
Sbjct: 167 APLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSE--GSTPLTSMPAS 224

Query: 176 QKQTLQNE-YSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPE------TQNPE 228
             +   +E  +   TP   S P  +  ++   P  +E  GPS  +  P       T+ P 
Sbjct: 225 TMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAE--GPSLSNSAPSGGSTPLTRMPL 282

Query: 229 TLEDIQSSSLQQ----EAPAQLPQLLEEEPSSMQQ--EAPALPPESSMESLT-LPNHEVS 281
           ++  + SS         A   +P +   E SS     E  ++P  +  E  T L +   S
Sbjct: 283 SVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPAS 342

Query: 282 VQPPGEDQAYYHLPNITVKPADVEVTITS-----------EPTNETESSQAQQETPIQFP 330
             P    +    +  +++ P D    +T+           E T+   S+ ++  TP+   
Sbjct: 343 TMPVATSE----MSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNM 398

Query: 331 EEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQ---PP 387
                     EA     +P ++ +  ++   +    S SP   E +     TP +   P 
Sbjct: 399 PVSTILVASSEASTTSTIP-VDSKTFVTTASEA---SSSPTTAEDTSIATSTPSEGSTPL 454

Query: 388 EHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGN 447
               V+ +P    +  +L++  V  K    Q+T + E S+   T+ V+   T+  S    
Sbjct: 455 TSMPVSTTPVASSEASNLSTTPVDSK---TQVTTSTEASSSPPTAEVNSMPTSTPSEGST 511

Query: 448 DVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAE 507
            +   ++       +P +S EA  L         S  P++   P  T  EA++    T  
Sbjct: 512 PLTSMSVS-----TMPVASSEASTL---------STTPVDTSTPVTTSSEASSS--STTP 555

Query: 508 EGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTM 567
           EG S  T   +   TP     V  +    S  +  +  P D    +T  S  E   S T 
Sbjct: 556 EGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSS--EASSSSTT 613

Query: 568 KETPTQPPKK------VVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP 621
            E  + P          +  + V   +   +     +  PV  +  V         T   
Sbjct: 614 AEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTT---STEATSSS 670

Query: 622 TTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVE 681
           TT  G S P   T      P  ++P    +       T +T  P+D    +T  +     
Sbjct: 671 TTAEGTSMPTS-TYTEGSTPLTSMPVNTTLVASSEASTLSTT-PVDTSTPVTTSTEASSS 728

Query: 682 PSTA----LMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKP 737
           P+TA    + T+ P  G   +T  P  K     S  +  +  PLD    ITT  +TE   
Sbjct: 729 PTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITT--STEASC 786

Query: 738 SPTTEETSTQP---PDLGLAIIPE-PTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGP 793
           SPTT E ++ P   P  G  ++   P + T  ++    T +  P    +   + TEV+  
Sbjct: 787 SPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSS 846

Query: 794 PTELEPAQDSLVQSESYTQNK 814
           PT   PA+ + + + +Y++ +
Sbjct: 847 PT---PAEGTSMPTSTYSEGR 864



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 160/776 (20%), Positives = 266/776 (34%), Gaps = 66/776 (8%)

Query: 71   SPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQ 130
            S  +P L + P     +    +S +   P +S   ++    T       P+  E      
Sbjct: 2098 SEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVI----TSTEVSSSPIPTEGTSMQT 2153

Query: 131  QDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSS--TD 188
                D+ +P   +PVS   +        S   +   T   ++ +++     +E +S  T 
Sbjct: 2154 STYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTS 2213

Query: 189  TPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEP-ETQNPETLEDIQSSSLQQEAPAQLP 247
            TP  GS P      S  P   SE    S     P +T  P T     +SS        +P
Sbjct: 2214 TPSEGSTPFTSMPVSTMPVVTSEA---STLSATPVDTSTPVTTSTEATSSPTTAEGTSIP 2270

Query: 248  QLLEEEPSSMQQEAPA---LPPESSMESL-TLP---------NHEVSVQPPGEDQAYYHL 294
                 E ++     P    L   S + +L T P         + E S  PP  +     +
Sbjct: 2271 TSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGT--SM 2328

Query: 295  PNITVKPADVEVT--------ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP 346
            P  T    +  +T        + S  T+   ++ A   TP+    +   S T  +    P
Sbjct: 2329 PTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMP 2388

Query: 347  PVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLA 406
                 E    ++       P  S      S T  +T        E + SP     T    
Sbjct: 2389 TSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPT 2448

Query: 407  SPSVSVKPPDVQLTIAAEP--SAEVGT-----------SLVHQEATTRLSGSGNDVEPPA 453
            SP      P   + ++  P  S+E GT                EA++  + + + V P +
Sbjct: 2449 SPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPIS 2508

Query: 454  IQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSL 513
                G  LL        P+A   E S  S  P+++ +P  T  E ++    T+ EG S  
Sbjct: 2509 TASEGSTLLTSIPVSTTPVA-SPEASTLSTTPVDSNSPVVTSTEISSS--ATSAEGTSMP 2565

Query: 514  THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSP-TMKET-- 570
            T   +   TP     V  +P   S  +  +  P+D    +T  + TE   SP T K+T  
Sbjct: 2566 TSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVT--TSTETSSSPTTAKDTSM 2623

Query: 571  PTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTP 630
            P   P +V   L      T P    + +    +P  T  L+      +  PTT  G S P
Sbjct: 2624 PISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMP 2683

Query: 631  PKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTA----L 686
               +    +   +T          +S  +  +  P+D    +T  +     P+TA    +
Sbjct: 2684 --TSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSM 2741

Query: 687  MTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETST 746
              + P  G   +T           S  +  +   +D  + +TT  +TE   SPTT E ++
Sbjct: 2742 RISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTT--STEASSSPTTAEVTS 2799

Query: 747  Q----PPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELE 798
                 P +    +   P   T  +++   T +  P    T   + T+ +  PT  E
Sbjct: 2800 MPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAE 2855



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 149/686 (21%), Positives = 230/686 (33%), Gaps = 70/686 (10%)

Query: 170  LSTPQSQKQTL--QNEYSSTDTPYPGSLPP-----ELRVKSDEPPGPSEQVGPSQFHLEP 222
            L+TP   K  +   NE SS+ TP  G+  P     E R      P  +  V  S   +  
Sbjct: 1299 LTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILS 1358

Query: 223  ET----QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAP-ALPPESSMESLTLPN 277
             T      P T      SS        +P     E ++     P +  P  S E+ TL  
Sbjct: 1359 TTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSA 1418

Query: 278  HEVSVQPPGEDQAYYHLPNITVK--------PADVEVTITSEPTNETESSQAQQETPIQF 329
              V    PG   A       T +        P++ +  + S P + T  + ++  T    
Sbjct: 1419 TPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTT 1478

Query: 330  PEEVEPSATQQEAPIEPPVPPMEHELSISEQQQ--------PVQPSE-SPREVESSPTQQ 380
            P +         A    P P     ++IS   +        PV  +  +  E+ S  T  
Sbjct: 1479 PVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTP 1538

Query: 381  ETPGQPPEHHEVTVSPPG-------HHQTHHLASPSVSVKPPDVQLTIAAEP-------- 425
                 P   +    S P           T+   S  ++  P    L +++E         
Sbjct: 1539 AVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPI 1598

Query: 426  -SAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE 484
             S    T+     ++T   GS   +  P+    G PLL        P+A   E S  S  
Sbjct: 1599 DSKTQVTASTEASSSTTAEGSSMTISTPS---EGSPLLTSIPVSTTPVA-SPEASTLSTT 1654

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
            P+++ +P  T  E ++    T  EG S  T      +TP     V   P   S ++  + 
Sbjct: 1655 PVDSNSPVITSTEVSSS--PTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLST 1712

Query: 545  QPLDLGFTITPESKTEVELSPTMKETPTQP---PKKVVPQLRVYQGVTNPTPGQDQAQHP 601
             P+D    +T  + TE   SPT  E  + P   P +    L      T P    + +   
Sbjct: 1713 TPVDNSTPVT--TSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLS 1770

Query: 602  VSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRA 661
             +P  T   +      T  PTT  G S P   T+     P  + P        +S  +  
Sbjct: 1771 ATPIDTSTPVTTSTEATSSPTTAEGTSIPTS-TLSEGMTPLTSTP-VSHTLVANSEASTL 1828

Query: 662  TVQPLDLGFTITPKSMTEVEPSTALMTT-APPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            +  P+D        S + V  STA+ ++  P  G    T  PS+   A  S     T   
Sbjct: 1829 STTPVD--------SNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVA 1880

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGH---STALEKTTAPRP 777
                 T++T P     P  T  + S+ P     + +P  T   G    ++    TT    
Sbjct: 1881 SSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVAS 1940

Query: 778  DRVQTLHRSLTEVTGPPTELEPAQDS 803
              + TL  +L +   P T    A  S
Sbjct: 1941 SEINTLSTTLADTRTPVTTYSQASSS 1966



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 171/856 (19%), Positives = 280/856 (32%), Gaps = 92/856 (10%)

Query: 43   VKDPLQLTSNPLGPPESWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQES 102
            V   + +T++        ++  +  P  +P   + P      +H  P ASSE        
Sbjct: 2776 VDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHT-PVASSEAGTLSTTP 2834

Query: 103  TENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAE 162
             +   P + T   A   P   E  +       +  +    +PVS   +    A   S   
Sbjct: 2835 VDTSTP-VTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTP 2893

Query: 163  I---IGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFH 219
            +   I +T   +   S   T +       TP   S P    + S  P   SE    S   
Sbjct: 2894 VDTSIPVTTS-TEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEA---STLS 2949

Query: 220  LEP-ETQNPETLEDIQSSSLQQEAPAQLP-QLLEEEPSSMQQEAPALPPESSMESLTLPN 277
              P +T+ P T     SSS        +P     E  + +   + +  P +S E+ TL  
Sbjct: 2950 TTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSR 3009

Query: 278  HEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSA 337
                   P            T +   + ++  SE +    S      TP+  PE    S 
Sbjct: 3010 TPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVST-TPVAIPEASTLST 3068

Query: 338  T--QQEAPI-------EPPVPPMEHELSISEQQQPVQP------------SESPREVESS 376
            T     +P+         P P     + IS   +   P            S +   + ++
Sbjct: 3069 TPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTT 3128

Query: 377  PTQQETP-GQPPEHHEVTVSPPGHHQ---THHLASPSVSVKPPDVQLTIAAEPSAEVGTS 432
            P    TP     E H    +  G      T    S  ++  P    L +++E S    T 
Sbjct: 3129 PVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATP 3188

Query: 433  L-------VHQEATTRLSGSGNDVEPPAIQHGGPPL--LPESSEEAGPLAVQQETSFQSP 483
            +          EAT+  +  G  +       G  PL  +P S+    P+A   E S  S 
Sbjct: 3189 VDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNT---PVA-SSEASILST 3244

Query: 484  EPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQAT 543
             P+++  P  T  EA++  P    EG S  T   +   TP     V       S  +  +
Sbjct: 3245 TPVDSNTPLTTSTEASSSPPTA--EGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLS 3302

Query: 544  VQPLDLGFTITPESKTEVELSPTMKE---TPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
              P D    +T  S  +   SP + +    PT    +    L      T P    + +  
Sbjct: 3303 TTPADTSTPVTTYS--QASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTL 3360

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKH---PEVTLPHPDQVQTQHSH 657
              +P  T   +      +  PTT  G S P      SP     P  ++P         S 
Sbjct: 3361 STTPVDTSTPVTTSTEASLSPTTAEGTSIPTS----SPSEGTTPLASMP-VSTTPVVSSE 3415

Query: 658  LTRATVQPLDLGFTITPKSMTEVEPS----TALMTTAPPPGHPEVTLPPSDKGQAQHSHL 713
            +   +  P+D    +T  +     P+    T+L T+    G   +++ P        S  
Sbjct: 3416 VNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEA 3475

Query: 714  TQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLG------LAIIPEPTTETGHST 767
            +  +  P+D    +TT   T    SPTT E ++ P          L  +P  TT    S 
Sbjct: 3476 STLSTTPVDTSTPVTTSSPT--NSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSE 3533

Query: 768  ALEKTTAPRPDRVQTLHRSLTEVTGPPTELE--------PAQDS-----LVQSESYTQNK 814
            A   +T P      T   S ++ +  P  L+        P++ S     ++ S +Y  + 
Sbjct: 3534 ASTLSTTPVDS--NTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSS 3591

Query: 815  ALTAPEEHKASTSTNI 830
              + P       ST +
Sbjct: 3592 EASTPSTPSVDRSTPV 3607



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 165/734 (22%), Positives = 246/734 (33%), Gaps = 110/734 (14%)

Query: 165  GITRQLSTPQSQKQTLQNEYSS-TDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPE 223
            G T   S P S K    +E S+ + TP   S+P     ++   P  ++           +
Sbjct: 2572 GSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAK-----------D 2620

Query: 224  TQNPETLEDIQSSSLQQEAPAQLPQLLEEEP--SSMQQEAPALPPESSMESLTLPNHEVS 281
            T  P +     S+SL     + +P    E    S+   +   L   S+  S +    E S
Sbjct: 2621 TSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGS 2680

Query: 282  VQP---PGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSAT 338
              P   PGE      L NI V        + +   +   ++     TP+    E   S T
Sbjct: 2681 SMPTSTPGERST--PLTNILVSTT----LLANSEASTLSTTPVDTSTPVTTSAEASSSPT 2734

Query: 339  QQEAP---IEPPVPPMEHELSISEQQQPVQPSESPR----------------EVESSPTQ 379
              E     I  P        SI     PV  SE+                  E  SSPT 
Sbjct: 2735 TAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTT 2794

Query: 380  QETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEAT 439
             E    P      T +P      +H  +P  S +   +  T   + S  V TS     + 
Sbjct: 2795 AEVTSMPTSTPSETSTPLTSMPVNH--TPVASSEAGTLSTT-PVDTSTPVTTSTKASSSP 2851

Query: 440  TRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAA 499
            T   G    V P +    G  LL        P+A   E S  S  P++   P  T  E +
Sbjct: 2852 TTAEGI---VVPISTASEGSTLLTSIPVSTTPVA-SSEASTLSTTPVDTSIPVTTSTEGS 2907

Query: 500  AEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKT 559
            +  P TAE G S      +   TP    +V   P   S  +  +  P+D    +T  +  
Sbjct: 2908 SS-PTTAE-GTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVT--TSA 2963

Query: 560  EVELSPTMKETPTQP---PKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLT 616
            E   SPT  E  + P   P +    L      T P    + +    +P+ T   +     
Sbjct: 2964 EASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTE 3023

Query: 617  ITPEPTTEVGH----STPPKR----TIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDL 668
             +  PTT  G     STP +     T +      V +P    + T         V   ++
Sbjct: 3024 ASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEV 3083

Query: 669  GFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTIT 728
              + TP   T +  ST    + P  G P  T P +       S ++  +  P+D    +T
Sbjct: 3084 SSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTS------SAISTLSTTPVDTSTPVT 3137

Query: 729  TKPTTEVKPSPTTEETSTQP------------------------PDLGLAIIPEPT---- 760
            T  +TE   SPTT E ++ P                         D  L+  P  T    
Sbjct: 3138 T--STEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPV 3195

Query: 761  ---TETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPP---TELEPAQDSLVQSESYTQNK 814
               TE   ST  E T+ P      T    +T +T  P   T +  ++ S++ +     N 
Sbjct: 3196 TTSTEATSSTTAEGTSIP----TSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNT 3251

Query: 815  ALTAPEEHKASTST 828
             LT   E  +S  T
Sbjct: 3252 PLTTSTEASSSPPT 3265



 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 130/590 (22%), Positives = 202/590 (34%), Gaps = 81/590 (13%)

Query: 267  ESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETP 326
            E+S    T     + +  P E       P +T  P  +   +TS   +   ++     +P
Sbjct: 783  EASCSPTTTEGTSMPISTPSEGS-----PLLTSIPVSI-TPVTSPEASTLSTTPVDSNSP 836

Query: 327  IQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQ----------------QPVQ---PS 367
            +    EV  S T  E    P     E    ++                    PV    P 
Sbjct: 837  VTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPV 896

Query: 368  ESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQL-TIAAEP- 425
             +  E  SSPT  E    P        S PG   T   + P  +      +  T++A P 
Sbjct: 897  TNSTEARSSPTTSEGTSMP-------TSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPV 949

Query: 426  --SAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP 483
              S  V TS     + T   G+      P+   G  PL   S+  +  L    E S  S 
Sbjct: 950  DTSTPVTTSTEATSSPTTAEGTSIPTSTPS--EGTTPLT--STPVSHTLVANSEASTLST 1005

Query: 484  EPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQAT 543
             P+++  P  T  EA++  P    EG S  T   +   TP                   T
Sbjct: 1006 TPVDSNTPLTTSTEASS--PPPTAEGTSMPTSTPSEGSTP------------------LT 1045

Query: 544  VQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP-- 601
              P+      + E+ T +  +P    TP     +         G + PT    +   P  
Sbjct: 1046 RMPVSTTMVASSETST-LSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLT 1104

Query: 602  ---VSPSVTVQLLDLGLTITPEPTT-EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSH 657
               VS  + V      L+ TP  T+  V  ST    +  + +   +    P +  T  + 
Sbjct: 1105 SVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLAS 1164

Query: 658  LTRATVQPLDLGFTITPKSMTEVEPSTALMTT----APPPGHPEVTLPPSDKGQAQHSHL 713
            +  +T   L +       S T V+  T + T+    +PPP     ++P S  G+ + + L
Sbjct: 1165 MPVSTT--LVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGE-RSTPL 1221

Query: 714  TQATVQPLDLEL----TITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTAL 769
            T   V+   +      T++T P     P  T+ ETS+ P       +P  TT  G ST L
Sbjct: 1222 TSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEG-STLL 1280

Query: 770  EKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAP 819
              T+ P    + T   + T +T P     P   S   S S T  +  + P
Sbjct: 1281 --TSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMP 1328



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 155/733 (21%), Positives = 240/733 (32%), Gaps = 73/733 (9%)

Query: 89   PSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPK 148
            P ASS +        +N  P + T   A   P   E          +  +P   +PVS  
Sbjct: 1701 PVASSAISTLSTTPVDNSTP-VTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTT 1759

Query: 149  KLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPG 208
             +    A   S   I       STP     T   E +S+ T   G+  P   +     P 
Sbjct: 1760 PVLSSEASTLSATPI-----DTSTPV----TTSTEATSSPTTAEGTSIPTSTLSEGMTPL 1810

Query: 209  PSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPES 268
             S  V  +       +    T  D  S  +   A +  P      P+     A + P E 
Sbjct: 1811 TSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPT-----PAEGTSIATSTPSEG 1865

Query: 269  SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQ 328
            S    ++P    +V    E       P +T  P      ++S PT    SS      P  
Sbjct: 1866 STALTSIPVSTTTVAS-SETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSM-----PTS 1919

Query: 329  FPEEVEPSATQQEAPIEPPVPPMEHELS--ISEQQQPVQPSESPREVESSPTQQETPGQP 386
             P E  P  T              + LS  +++ + PV       +  SSPT  +    P
Sbjct: 1920 TPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYS---QASSSPTTADGTSMP 1976

Query: 387  -PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL-VHQEATTRLSG 444
             P + E               S  ++  P    L +++E S    T +     ATT   G
Sbjct: 1977 TPAYSE--------------GSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEG 2022

Query: 445  SGNDVEPPAIQHGGPPLLPESSEEAGPLA---------VQQETSFQSPEPINNENPSPTQ 495
            S +    P    G        SE   PLA         V  E +  S  P++++      
Sbjct: 2023 SSS----PTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNS 2078

Query: 496  QEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITP 555
             EA++           S   + +P  T    +      PE S L+   V       T T 
Sbjct: 2079 TEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTE 2138

Query: 556  ESKTEVELSPTMKETPTQPPKKV-VPQLRVYQGVTNPTPGQDQAQHPVSPSVTV-QLLDL 613
             S + +    T  +T T   ++  +  + V   V   +     +  PV  S  V    + 
Sbjct: 2139 VSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEA 2198

Query: 614  GLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTIT 673
              + T    T +  STP + +      P  T+P    V T  +    AT  P+D    +T
Sbjct: 2199 RSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMP----VVTSEASTLSAT--PVDTSTPVT 2252

Query: 674  PKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTT 733
              +     P+TA  T+ P     E T P +      H+ +  + V       T++T P  
Sbjct: 2253 TSTEATSSPTTAEGTSIPTSTLSEGTTPLTSI-PVSHTLVANSEVS------TLSTTPVD 2305

Query: 734  EVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALE---KTTAPRPDRVQTLHRSLTEV 790
               P  T+ E S+ PP      +P  T+  G++        TT        TL  +  + 
Sbjct: 2306 SNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADT 2365

Query: 791  TGPPTELEPAQDS 803
            + P T    A  S
Sbjct: 2366 STPVTTYSQAGSS 2378



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 175/835 (20%), Positives = 283/835 (33%), Gaps = 130/835 (15%)

Query: 50   TSNPLGPPESWSSHSSHFPRE-----SPHAPTLPADPWDFDHLGPSASSEMPAPPQESTE 104
            TS P+  P   S   +  P       SP A TL   P D  +   + S+E+ + P  +  
Sbjct: 794  TSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVD-SNSPVTTSTEVSSSPTPAEG 852

Query: 105  NLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKK-LKKDPAQRWSLAEI 163
              +P   +  S G  PL     +++       +S     PV     +      R S    
Sbjct: 853  TSMP--TSTYSEGRTPLTSMP-VSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTS 909

Query: 164  IGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPE 223
             G +   STP      L +   ST TP   S   E R  S  P   S  V  S       
Sbjct: 910  EGTSMPTSTPGEGSTPLTSMPDST-TPVVSS---EARTLSATPVDTSTPVTTST----EA 961

Query: 224  TQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSS----MQQEAPALP--PESSMESLTLPN 277
            T +P T E    +S+    P++    L   P S       EA  L   P  S   LT   
Sbjct: 962  TSSPTTAE---GTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTST 1018

Query: 278  HEVSVQPPGEDQAYYHLPNITVKPADVEVT--------ITSEPTNETESSQAQQETPIQF 329
               S  P  E  +   +P  T       +T        + S  T+   ++ A   TP+  
Sbjct: 1019 EASSPPPTAEGTS---MPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTT 1075

Query: 330  PEEVEPSATQQEAPIEPPVP-----------PMEHELSISEQQQPVQ--------PSESP 370
              +   S+T  +    P              P+   L +S +   +         P  + 
Sbjct: 1076 YSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTS 1135

Query: 371  REVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVG 430
             E  SSPT  E    P        SPP    T  LAS  VS       L +++E +  + 
Sbjct: 1136 TEASSSPTTAEGTSIP-------TSPPSEGTTP-LASMPVSTT-----LVVSSEANT-LS 1181

Query: 431  TSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLA---------VQQETSFQ 481
            T+ V  +     S   +   P A     P   P   E + PL             E S  
Sbjct: 1182 TTPVDSKTQVATSTEASSPPPTAEVTSMPTSTP--GERSTPLTSMPVRHTPVASSEASTL 1239

Query: 482  SPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQ 541
            S  P++   P  T  E ++  P TAE G S  T     + T E   ++ + P   + +T 
Sbjct: 1240 STSPVDTSTPVTTSAETSSS-PTTAE-GTSLPT-----STTSEGSTLLTSIPVSTTLVTS 1292

Query: 542  ATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP 601
                 L    T   ++K  V  S  +  +PT             +G + PT    + + P
Sbjct: 1293 PEASTL---LTTPVDTKGPVVTSNEVSSSPTPA-----------EGTSMPTSTYSEGRTP 1338

Query: 602  VSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPE----VTLP--HPDQVQTQ- 654
            ++       L     I+   TT V +STP   +  +   P      ++P  +P +  T  
Sbjct: 1339 LTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPL 1398

Query: 655  -----------HSHLTRATVQPLDLGFTITPKSMTEVEPSTA----LMTTAPPPGHPEVT 699
                        S  +  +  P+D     T  +     P+TA    + T+ P  G   + 
Sbjct: 1399 TSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLK 1458

Query: 700  LPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT--TEETSTQPPDLGLAIIP 757
              P       +S  +  +  P+D    + T       P+P   T    + P +   A+  
Sbjct: 1459 SIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTS 1518

Query: 758  EPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQ 812
             P + T  +++   + +  P    T   + ++ +  PT    A  + +Q+ +Y++
Sbjct: 1519 IPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPT---TADGTSMQTSTYSE 1570



 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 170/825 (20%), Positives = 268/825 (32%), Gaps = 116/825 (14%)

Query: 89   PSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPK 148
            P  SSE         +   P + T   A   P   E          +  +P   +PVS  
Sbjct: 3351 PVVSSEASTLSTTPVDTSTP-VTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTT 3409

Query: 149  KLKKDPAQRWSLAEIIGITR-QLSTPQSQKQTLQNEYS-STDTPYPGSLPPELRVKSDEP 206
             +        S   +   T    ST  S   T+    S  T T   GS P  +   S  P
Sbjct: 3410 PVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTP 3469

Query: 207  PGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPP 266
               SE    S       T   +T   + +SS    +P                E  ++P 
Sbjct: 3470 VASSEASTLS-------TTPVDTSTPVTTSSPTNSSPTTA-------------EVTSMPT 3509

Query: 267  ESSMESLT-LPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQET 325
             ++ E  T L N  VS  P    +A      ++  P D    +TS  +  + S    Q T
Sbjct: 3510 STAGEGSTPLTNMPVSTTPVASSEA----STLSTTPVDSNTFVTSS-SQASSSPATLQVT 3564

Query: 326  PIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQ 385
             ++     E S++     +          ++ SE   P  PS       ++ TQ  +   
Sbjct: 3565 TMRMSTPSEGSSSLTTMLLSSTY------VTSSEASTPSTPSVDRSTPVTTSTQSNSTPT 3618

Query: 386  PPEHHEVTVSPPGHHQTHHLASP----SVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTR 441
            PPE   + +S P    T     P    SV++       T+  + S  V TS     +   
Sbjct: 3619 PPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVT 3678

Query: 442  LSGSGNDVEPPAIQHGGPPL--LPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAA 499
              G+   +  P+   G  PL  +P S+          E S  S   +    P  T  EA 
Sbjct: 3679 PEGTTMPIWTPS--EGSTPLTTMPVSTTRV----TSSEGSTLSTPSVVTSTPVTTSTEAI 3732

Query: 500  AEH------------PQTAEEGESSLTHQEAP------AQTPEFPNVVVAQPPEHSHLTQ 541
            +              P       +++     P      + TP  P+V  +     +  ++
Sbjct: 3733 SSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSM--SMTTASE 3790

Query: 542  ATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP 601
             +  P  L  T T    T  E S  +      P   + P     +  T  TP  D +   
Sbjct: 3791 GSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPS----EASTLSTPPGDTSTPL 3846

Query: 602  VSP------SVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQH 655
            ++       S+  ++  + ++IT E       STP    +VS      TLP      T  
Sbjct: 3847 LTSTKAGSFSIPAEVTTIRISITSE------RSTPLTTLLVS-----TTLP------TSF 3889

Query: 656  SHLTRATVQPLDLGFTITPKSMTEVEP--------STALMTTAPPPG------HPEVTLP 701
               + A+  PLD   T TP + T   P        S +++T    PG         VT  
Sbjct: 3890 PGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSS 3949

Query: 702  PSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET----STQPPDLGLAIIP 757
             +D   A    ++   +   +L    T+  +T    S T E T    +T  P   + +  
Sbjct: 3950 TADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMST 4009

Query: 758  EPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALT 817
             P+T    S     T+A       T H S +  T P T   P+ +S   S   +     T
Sbjct: 4010 APSTPRTTSRGC-TTSASTLSATSTPHTSTSVTTRPVT---PSSESSRPSTITSHTIPPT 4065

Query: 818  APEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNT 862
             P  H ++  T      T   E ++ +    +   R    P   T
Sbjct: 4066 FPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTT 4110



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 76/352 (21%), Positives = 128/352 (36%), Gaps = 38/352 (10%)

Query: 477 ETSFQSPEP-INNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPE 535
           E+S  S  P +++   +PT+    +E    +     S T   +   TPE  +V ++ P E
Sbjct: 95  ESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSE 154

Query: 536 HS-HLTQATVQPLDL-------GFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQG 587
            S   T A V    L         T   +  T +  S     +PT P    +P+    +G
Sbjct: 155 ESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEG 214

Query: 588 VTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPH 647
            T P      +   V+ S  + LL   + I+   T     S+ P     + + P ++   
Sbjct: 215 ST-PLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSP----TTAEGPSLSNSA 269

Query: 648 PDQVQTQ------------HSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
           P    T              S  +  +  P      +   +     P+TA  T+ P   +
Sbjct: 270 PSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTY 329

Query: 696 PEVTLP----PSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDL 751
            E + P    P+       S ++  ++ P+D    +TT  +TE    PTT E ++     
Sbjct: 330 TEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTT--STEPSSLPTTAEATSMLTST 387

Query: 752 GLAIIPEPTTETGHSTAL-----EKTTAPRPDRVQTLHRSLTEVTGPPTELE 798
            L+    P T    ST L       TT+  P   +T   + +E +  PT  E
Sbjct: 388 -LSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAE 438



 Score = 33.1 bits (74), Expect = 2.4
 Identities = 61/264 (23%), Positives = 103/264 (39%), Gaps = 39/264 (14%)

Query: 1236 SFTQEHKAAVSVLKPFSKGAPS-TSSPAKALPQVRDRSKDLTHAISILESAKARVTNTKT 1294
            S T    +++++  P S+G+P  TS P    P     +  L+   + ++S    +T+T+ 
Sbjct: 1612 SSTTAEGSSMTISTP-SEGSPLLTSIPVSTTPVASPEASTLS--TTPVDSNSPVITSTEV 1668

Query: 1295 SKPIVHAR------KKYRFHKTR-SHVTHRTTKVKKSPKVRKKSYLSRLMLANRLPFSAA 1347
            S     A         Y   +T  + +T RTT V  S      S LS   + N  P + +
Sbjct: 1669 SSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAI----STLSTTPVDNSTPVTTS 1724

Query: 1348 KSLINSPSQGAFSSLGDLSPQEN------------PFL--EVSALSEHFIEKNNTKHTTA 1393
                +SP+    +S+ + +P E             P L  E S LS   I+  +T  TT+
Sbjct: 1725 TEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPID-TSTPVTTS 1783

Query: 1394 RNAFEENDFMENTNMPEGTISE------NTNYNHPPEADSAGTAFNLGPTVKQTETKWEY 1447
              A       E T++P  T+SE      +T  +H   A+S  +  +  P    +      
Sbjct: 1784 TEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPV---V 1840

Query: 1448 NNVGTDLSPEPKSFNYPLLSSPGD 1471
             +     SP P        S+P +
Sbjct: 1841 TSTAVSSSPTPAEGTSIATSTPSE 1864


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 146/598 (24%), Positives = 197/598 (32%), Gaps = 88/598 (14%)

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            P  +  T T  PT    S+Q+   TPI     V P+ T       P   P+    +++  
Sbjct: 1313 PTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT 1371

Query: 361  QQPV---QPSESPREVES------SPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVS 411
              P     P+ +P    +      +PT  +TP   P     TV+P     T         
Sbjct: 1372 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTP-----TPTPTGTQTP 1426

Query: 412  VKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGP 471
               P    T         GT      A T  S       P   Q   P   P ++     
Sbjct: 1427 TTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQ--TPTTTPITT----- 1479

Query: 472  LAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVA 531
                  T   +P P   + P+PT     A    T      + T  + P  TP      V 
Sbjct: 1480 ----TTTVTPTPTPTGTQTPTPT-----AITTTTTVTPTPTPTGTQTPTSTPITTTTTVT 1530

Query: 532  QPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNP 591
              P  +     T  P+    T+TP        +PT  +TPT  P               P
Sbjct: 1531 PTPTPTGTQTPTPTPISTTTTVTPTP------TPTGTQTPTTTPITTTT-------TVTP 1577

Query: 592  TPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTL---PHP 648
            TP     Q P     T  L+    T+TP PT      T  K T V+P     T+   P P
Sbjct: 1578 TPTPTGTQTP-----TTVLITTTTTMTPTPT-----PTSTKSTTVTPITTTTTVTATPTP 1627

Query: 649  DQVQTQH----SHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSD 704
               QT      S  T  T  P     +  P + T   P   L T+ PP   PE + P + 
Sbjct: 1628 TGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPP---PESSTPQTS 1684

Query: 705  KGQAQHSHLTQAT----VQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPT 760
            +  +  S LT++T      P  +E+T T  P+T   P+ T+   +  PP       P  T
Sbjct: 1685 RSTS--SPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPP-STTTSPPGT 1741

Query: 761  TETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPP---------TELEPAQDSLVQSESYT 811
               G +T    ++AP P  VQT   S    T  P         T L P   S++      
Sbjct: 1742 PTRGTTTG--SSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVL--ICCV 1797

Query: 812  QNKALTAP-EEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFT 868
             N    AP EE    T  + C    C    LSC            P P P     T T
Sbjct: 1798 LNDTYYAPGEEVYNGTYGDTCYFVNCS---LSCTLEFYNWSCPSTPSPTPTPSKSTPT 1852



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 97/389 (24%), Positives = 127/389 (32%), Gaps = 61/389 (15%)

Query: 514  THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQ 573
            T  E P  TP      V   P  +     T  P+    T+TP        +PT  +TPT 
Sbjct: 1306 TTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP------TPTGTQTPTT 1359

Query: 574  PPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKR 633
             P               PTP     Q P +  +T        T+TP P T  G  TP   
Sbjct: 1360 TPITTTT-------TVTPTPTPTGTQTPTTTPITTT-----TTVTPTP-TPTGTQTPTST 1406

Query: 634  TIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITP---KSMTEVEPSTALMTTA 690
             I +      T P P   QT        T  P+    T+TP    + T+    TA+ TT+
Sbjct: 1407 PITTTTTVTPT-PTPTGTQT-------PTTTPITTTTTVTPTPTPTGTQAPTPTAITTTS 1458

Query: 691  -------PPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEE 743
                   P       T P +       +     T  P    +T TT  T    P+ T   
Sbjct: 1459 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTP 1518

Query: 744  TSTQPPDLGLAIIPEPT-------TETGHSTALEKTTAPRPDRVQTLH----RSLTEVTG 792
            TST P      + P PT       T T  ST    T  P P   QT       + T VT 
Sbjct: 1519 TST-PITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1577

Query: 793  PPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCT-------CGDEMLSCID 845
             PT       + V   + T       P   K++T T I    T        G +  + I 
Sbjct: 1578 TPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIP 1637

Query: 846  LNPEQRLRQVPVPE-----PNTHNGTFTI 869
            ++    +   P P      P TH  T  I
Sbjct: 1638 ISTTTTVTPTPTPTTGSTGPPTHTSTAPI 1666



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 96/494 (19%), Positives = 149/494 (30%), Gaps = 98/494 (19%)

Query: 165  GITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPET 224
            G     +TP +   T+    + T T  P S P          P P+    P+     P T
Sbjct: 1376 GTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTT---TPIT 1432

Query: 225  QNPETLEDIQSSSLQQEAPAQLP--QLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSV 282
                       +  Q   P  +     +   P+    + P   P ++  ++T        
Sbjct: 1433 TTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 1492

Query: 283  QPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEA 342
            Q P               P  +  T T  PT     +Q    TPI     V P+ T    
Sbjct: 1493 QTP--------------TPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGT 1538

Query: 343  PIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSP---PGH 399
                P P     +S +    P            +PT  +TP   P     TV+P   P  
Sbjct: 1539 QTPTPTP-----ISTTTTVTPT----------PTPTGTQTPTTTPITTTTTVTPTPTPTG 1583

Query: 400  HQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGP 459
             QT     P+  +      +T    P++   T++     TT ++ +     P       P
Sbjct: 1584 TQT-----PTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTAT-----PTPTGTQTP 1633

Query: 460  PLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAP 519
             ++P S+           T   +P P       PT       H  TA   E + ++    
Sbjct: 1634 TMIPIST---------TTTVTPTPTPTTGSTGPPT-------HTSTAPIAELTTSNPPPE 1677

Query: 520  AQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVV 579
            + TP+               +++T  PL    T+         L P ++ T T PP    
Sbjct: 1678 SSTPQ--------------TSRSTSSPLTESTTLLS------TLPPAIEMTSTAPPS--- 1714

Query: 580  PQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPK 639
                     T   P      H +SP  +      G   TP   T  G S+ P  + V   
Sbjct: 1715 ---------TPTAPTTTSGGHTLSPPPSTTTSPPG---TPTRGTTTGSSSAPTPSTVQTT 1762

Query: 640  HPEVTLPHPDQVQT 653
                  P P  + T
Sbjct: 1763 TTSAWTPTPTPLST 1776



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 47/199 (23%), Positives = 65/199 (32%), Gaps = 24/199 (12%)

Query: 681  EPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT 740
            +P+T   TT   P    +T   +       +     T  P+    T+T  PT     +PT
Sbjct: 1299 QPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPT 1358

Query: 741  TEETSTQPPDLGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTE 789
            T   +T        + P PT   T+T  +T +  TT     P P   QT       + T 
Sbjct: 1359 TTPITTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTT 1413

Query: 790  VTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPE 849
            VT  PT       +     + T       P   +A T T I    T        +   P 
Sbjct: 1414 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTST--------VTPTPT 1465

Query: 850  QRLRQVPVPEPNTHNGTFT 868
                Q P   P T   T T
Sbjct: 1466 PTGTQTPTTTPITTTTTVT 1484


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 84.3 bits (207), Expect = 9e-16
 Identities = 163/743 (21%), Positives = 233/743 (31%), Gaps = 125/743 (16%)

Query: 154  PAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPY-PGSLPPEL-RVKSDEPPGPSE 211
            P Q W +         LS+      +     S T TP  P +L        S EPP P+ 
Sbjct: 1217 PTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTT 1276

Query: 212  QVGPSQFHLEPET---QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPES 268
             V P      P T   ++  T   +  ++ +  A    P       S+ +       P +
Sbjct: 1277 AVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPAT 1336

Query: 269  SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTIT---SEPTNETESSQAQQET 325
            S  S TLP    + + PG        P  T  PA      T    +PT  T +   Q  T
Sbjct: 1337 SGTSPTLPK-STNQELPGTTATQTTGPRPT--PASTTGPTTPQPGQPTRPTATETTQTRT 1393

Query: 326  PIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSES------PREVESSPTQ 379
              ++     P  T        PVP      + S       P+ S      P  V    T 
Sbjct: 1394 TTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTS 1453

Query: 380  QETPGQ----PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVH 435
              TP       P H ++  S   H        P  ++K      T         GTS  H
Sbjct: 1454 LVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAH 1513

Query: 436  QEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGP-----------LAVQQETSFQSPE 484
               +T  + +       +  H  P + P S+    P                 TS + P 
Sbjct: 1514 SSFSTNKTPTSLHSHTSSTHH--PEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPP 1571

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTH-------QEAPAQTPEF------PNVVVA 531
            P    +P       ++  P TA   +++ T+          P   P F      P+    
Sbjct: 1572 PFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTV 1631

Query: 532  QPPEHSHL-TQATVQPLDLGFTITP----ESKTEVELSPTMKETPTQPPKKVVPQLRVYQ 586
              P H+ + T A++  +  G TI P    ++      +PTM  T T    + +  L   +
Sbjct: 1632 ITPTHAQMATSASIHSMPTG-TIPPPTTLKATGSTHTAPTMTLT-TSGTSQALSSLNTAK 1689

Query: 587  GVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIV---------- 636
              T+         H  + S +         ITP PT+     TPP               
Sbjct: 1690 TSTSLHSHTSSTHHAEATSTST------TNITPNPTST---GTPPMTVTTSGTSQSRSSF 1740

Query: 637  --------------SPKHPEVTLPHPDQVQTQH---------SHLTRATVQPLDLGFT-- 671
                          S  HPEVT      +   H         +H T AT   L   FT  
Sbjct: 1741 STAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTH 1800

Query: 672  -----ITPKSMTEVEPSTALMTTA--PPPGHPEVTLP------------PSDKGQAQHSH 712
                  TP S T    +T+  TT   P P HP  TLP            PS       +H
Sbjct: 1801 SPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTH 1860

Query: 713  LTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKT 772
               AT   +    T T  P T +K    T  T T PP   +      T+++  S +  KT
Sbjct: 1861 TQMATSASIHSMPTGTIPPPTTIK---ATGSTHTAPP---MTPTTSGTSQSPSSFSTAKT 1914

Query: 773  TAPRPDRVQTLHRSLTEVTGPPT 795
            +   P    + H    EVT   T
Sbjct: 1915 STSLPYHTSSTHH--PEVTPTST 1935



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 156/719 (21%), Positives = 241/719 (33%), Gaps = 143/719 (19%)

Query: 144  PVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKS 203
            P  P+         +S + +   T  + TP   +        S  T   G++PP   +K+
Sbjct: 1436 PSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPT---GTIPPPTTLKA 1492

Query: 204  D-----EPPGPSEQVGPSQFHLEPET-QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSM 257
                   PP      G SQ H    T + P +L    SS+   E        +   P+S 
Sbjct: 1493 TGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTST 1552

Query: 258  QQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETE 317
            +   P     S+  S   P       P G        P  +  P    +T TS  T  T 
Sbjct: 1553 RTRTPVAHTNSATSSRPPPPFTTHSPPTGSS------PFSSTGP----MTATSFKTTTTY 1602

Query: 318  SSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSP 377
             + +  +T +  P  V P +T         V P  H +        + P+ +     +S 
Sbjct: 1603 PTPSHPQTTL--PTHVPPFSTSL-------VTPSTHTV--------ITPTHAQMATSASI 1645

Query: 378  TQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQE 437
                T   PP     T+   G   T    +P++++        +++  +A+  TSL    
Sbjct: 1646 HSMPTGTIPPP---TTLKATGSTHT----APTMTLTTSGTSQALSSLNTAKTSTSLHSHT 1698

Query: 438  ATTR----LSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSP 493
            ++T      S S  ++ P     G PP+   +S  +     Q  +SF + +     + S 
Sbjct: 1699 SSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTS-----QSRSSFSTAKT----STSL 1749

Query: 494  TQQEAAAEHPQTAEEGESSLT--HQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGF 551
                ++  HP+      +S+T  H     +TP             +H T AT   L   F
Sbjct: 1750 HSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPV------------AHTTSATSSRLPTPF 1797

Query: 552  TITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTN-PTPGQDQAQHPVS-PSVTVQ 609
            T          +S T   T T            +Q  T  PTP       P   PS +  
Sbjct: 1798 TTHSPPTGTTPISSTGPVTATS-----------FQTTTTYPTPSHPHTTLPTHVPSFSTS 1846

Query: 610  LLDLGLTITPEPTTEVGHSTPPKRTIVSPKH------------PEVTLPHPDQVQTQHSH 657
            L+                 TP   T++ P H            P  T+P P  ++   S 
Sbjct: 1847 LV-----------------TPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGST 1889

Query: 658  LTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQAT 717
             T   + P   G + +P S +  + ST+L        HPEVT  P+        H +  T
Sbjct: 1890 HTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT--PTSTTNITPKHTSTGT 1947

Query: 718  VQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALE---KTTA 774
              P    +  TT  ++   P+P T    T  P  G      P + TG  TA      TT 
Sbjct: 1948 RTP----VAHTTSASSSRLPTPFT----THSPPTG----SSPFSSTGPMTATSFQTTTTY 1995

Query: 775  PRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESY-----TQNKALTAPEEHKASTST 828
            P P   QT           PT + P   SLV   ++     T  +  T+   H   T T
Sbjct: 1996 PTPSHPQTT---------LPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGT 2045



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 116/566 (20%), Positives = 184/566 (32%), Gaps = 101/566 (17%)

Query: 325  TPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPG 384
            T I       PS +    P  P   P+      S +  P   S  P    ++ T Q T G
Sbjct: 1228 TTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSK--PTASSGEPPRPTTAVTPQATSG 1285

Query: 385  QPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSG 444
             PP                     S + KP   Q T  A  S     +    ++TTR + 
Sbjct: 1286 LPPT----------------ATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTM 1329

Query: 445  SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQ 504
            +     P     G  P LP+S+ +  P     +T+   P P            A+   P 
Sbjct: 1330 T----LPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTP------------ASTTGPT 1373

Query: 505  TAEEG--------ESSLTHQEAPAQTPEFPNVVVAQP----------------------- 533
            T + G        E++ T       TP+ P+   + P                       
Sbjct: 1374 TPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTY 1433

Query: 534  --PEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNP 591
              P H   T  T  P      +TP + T +  +PT  +  T       P   +    T  
Sbjct: 1434 PTPSHPETTLPTHVPPFSTSLVTPSTHTVI--TPTHAQMATSASNHSAPTGTIPPPTTLK 1491

Query: 592  TPGQDQAQHPVSPSVT-VQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQ 650
              G      P++P+ +         +    PT+   H++      V+P       P+P  
Sbjct: 1492 ATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTS 1551

Query: 651  VQTQH--SHLTRATVQPLDLGFTI-------TPKSMTEVEPSTALMTTA--PPPGHPEVT 699
             +T+   +H   AT       FT        +P S T    +T+  TT   P P HP+ T
Sbjct: 1552 TRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTT 1611

Query: 700  LP-------PSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLG 752
            LP        S    + H+ +T    Q +    +I + PT  + P  T + T +      
Sbjct: 1612 LPTHVPPFSTSLVTPSTHTVITPTHAQ-MATSASIHSMPTGTIPPPTTLKATGSTHTAPT 1670

Query: 753  LAIIPEPTTETGHSTALEKTTAPRPDRVQTLHR------SLTEVTGPPTELEPAQDSLVQ 806
            + +    T++   S    KT+        + H       S T +T  PT       ++  
Sbjct: 1671 MTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTT 1730

Query: 807  S------ESYTQNKALTAPEEHKAST 826
            S       S++  K  T+   H +ST
Sbjct: 1731 SGTSQSRSSFSTAKTSTSLHSHTSST 1756



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 122/611 (19%), Positives = 211/611 (34%), Gaps = 89/611 (14%)

Query: 171  STPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETL 230
            S+P S    +      T T YP    P+  + +  PP  +  V PS   +      P   
Sbjct: 1582 SSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVI----TPTHA 1637

Query: 231  EDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPN---HEVSVQPPGE 287
            +   S+S+       +P     + +     AP +   +S  S  L +    + S      
Sbjct: 1638 QMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSH 1697

Query: 288  DQAYYHLP-------NITVKPADV---EVTITSEPTNETESSQAQQETPIQFPE------ 331
              + +H         NIT  P       +T+T+  T+++ SS +  +T            
Sbjct: 1698 TSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTH 1757

Query: 332  --EVEPSATQQEAPIEPPV---PPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQP 386
              EV  ++T    P         P+ H  S +  + P   +       ++P     P   
Sbjct: 1758 HPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTA 1817

Query: 387  PEHHEVTVSP-PGHHQTH---HLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRL 442
                  T  P P H  T    H+ S S S+  P     I    +    ++ +H   T  +
Sbjct: 1818 TSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTI 1877

Query: 443  SGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEH 502
                  ++     H  PP+ P +S  +     Q  +SF + +     + S     ++  H
Sbjct: 1878 PPP-TTIKATGSTHTAPPMTPTTSGTS-----QSPSSFSTAKT----STSLPYHTSSTHH 1927

Query: 503  PQTAEEGESSLT--HQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTI------- 553
            P+      +++T  H     +TP             +H T A+   L   FT        
Sbjct: 1928 PEVTPTSTTNITPKHTSTGTRTPV------------AHTTSASSSRLPTPFTTHSPPTGS 1975

Query: 554  TPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDL 613
            +P S T   ++ T  +T T  P    PQ       T PT     +   V+PS    ++  
Sbjct: 1976 SPFSSTG-PMTATSFQTTTTYPTPSHPQ------TTLPTHVPPFSTSLVTPSTHTVIIT- 2027

Query: 614  GLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTIT 673
              T T   T+   HSTP             T+P P  ++   S  T   +     G + T
Sbjct: 2028 --THTQMATSASIHSTPTG-----------TVPPPTTLKATGSTHTAPPMTVTTSGTSQT 2074

Query: 674  PKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTT 733
              S +    S++ ++++        + PPS     Q  HL+ AT       ++ T + ++
Sbjct: 2075 HSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATT-----PVSTTNQLSS 2129

Query: 734  EVKPSPTTEET 744
               PSP+   T
Sbjct: 2130 SFSPSPSAPST 2140


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 166/735 (22%), Positives = 232/735 (31%), Gaps = 109/735 (14%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 3729 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 3784

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 3785 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3828

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 3829 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3879

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 3880 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3934

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3935 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3990

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3991 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4050

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 4051 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 4104

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 4105 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 4151

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSH----LTRATVQPLDLGFTITPKSMTEVEPSTALM 687
               I +      T P P   QT  +      T  T  P   G    P + T   P   L 
Sbjct: 4152 TTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELT 4210

Query: 688  TTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQ----PLDLELTITTKPTTEVKPSPTTEE 743
            T+ PPP   E + P + +  +  S LT++T      P  +E+T T  P+T   P+ T+  
Sbjct: 4211 TSNPPP---ESSTPQTSRSTS--SPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGG 4265

Query: 744  TSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPP--------- 794
             +  PP       P  T   G +T    ++AP P  VQT   S    T  P         
Sbjct: 4266 HTLSPPP-STTTSPPGTPTRGTTTG--SSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRT 4322

Query: 795  TELEPAQDSLVQSESYTQNKALTAP-EEHKASTSTNICELCTCGDEMLSCIDLNPEQRLR 853
            T L P   S++       N    AP EE    T  + C    C    LSC          
Sbjct: 4323 TGLRPYPSSVL--ICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS---LSCTLEFYNWSCP 4377

Query: 854  QVPVPEPNTHNGTFT 868
              P P P     T T
Sbjct: 4378 STPSPTPTPSKSTPT 4392



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 128/501 (25%), Positives = 158/501 (31%), Gaps = 109/501 (21%)

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            P D  +T  S PT           T    P    PS         PP       ++ +  
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTT---LPPTTTPSPPTTTTTTPPPTTTPSPPITTTTT 1447

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
              P      P    ++P    TP  P      T SPP    T   + P+ +   P    T
Sbjct: 1448 PPPTTTPSPPISTTTTPPPTTTPSPPT----TTPSPP----TTTPSPPTTTTTTPPPTTT 1499

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
                PS    T +    +TT L  +     P       PP    S     P+     TS 
Sbjct: 1500 ----PSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT--PPTST 1553

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
             +  P    +P PT                   T    P  TP  P      PP    +T
Sbjct: 1554 TTLPPTTTPSPPPTT------------------TTTPPPTTTPSPPTTTTPSPPT---IT 1592

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
              T  P     T TP        SP    T T PP             T P+P       
Sbjct: 1593 TTTPPP-----TTTP--------SPPTTTTTTPPP------------TTTPSP---PTTT 1624

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            P++P  +   L    T +P PTT    +TPP  T  SP  P  T P P         +T 
Sbjct: 1625 PITPPTSTTTLPPTTTPSPPPTTT---TTPPPTTTPSP--PTTTTPSPP--------ITT 1671

Query: 661  ATVQPLDLGFTITPKS--MTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATV 718
             T  P     T TP S   T   P T  MTT      P  T  PS       S +T  T 
Sbjct: 1672 TTTPPP----TTTPSSPITTTPSPPTTTMTT------PSPTTTPS-------SPITTTTT 1714

Query: 719  QPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPD 778
                   T +  PTT   PSPT   T+  PP   +  +P PTT     T+   TT P P 
Sbjct: 1715 P--SSTTTPSPPPTTMTTPSPT---TTPSPPTTTMTTLP-PTT-----TSSPLTTTPLPP 1763

Query: 779  RVQTLHRSLTEVTGPPTELEP 799
             +     S    T P T   P
Sbjct: 1764 SITPPTFSPFSTTTPTTPCVP 1784



 Score = 78.2 bits (191), Expect = 6e-14
 Identities = 92/372 (24%), Positives = 121/372 (32%), Gaps = 35/372 (9%)

Query: 459  PPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEA 518
            PP  P S+    P       +  +  P     PSP         P T      S T    
Sbjct: 1408 PP--PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPP 1465

Query: 519  PAQTPEFPNVVVAQP---PEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKET---PT 572
            P  TP  P    + P   P     T  T  P     T TP   T   ++P    T   PT
Sbjct: 1466 PTTTPSPPTTTPSPPTTTPSPPTTTTTTPPP-----TTTPSPPTTTPITPPASTTTLPPT 1520

Query: 573  QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGH---ST 629
              P             T P+P       P++P  +   L    T +P PTT       +T
Sbjct: 1521 TTPSPPTTTTTTPPPTTTPSP---PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT 1577

Query: 630  PPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMT- 688
            P   T  +P  P +T   P    T     T  T  P     T +P + T + P T+  T 
Sbjct: 1578 PSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT--TPSPPTTTPITPPTSTTTL 1635

Query: 689  ---TAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETS 745
               T P P     T PP     +  +     T  P     T TT P T    SP T  T+
Sbjct: 1636 PPTTTPSPPPTTTTTPPPTTTPSPPT-----TTTPSPPITTTTTPPPTTTPSSPIT--TT 1688

Query: 746  TQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLV 805
              PP   +   P PTT    S+ +  TT P      +   +      P T   P   ++ 
Sbjct: 1689 PSPPTTTMTT-PSPTTTP--SSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMT 1745

Query: 806  QSESYTQNKALT 817
                 T +  LT
Sbjct: 1746 TLPPTTTSSPLT 1757



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 82/289 (28%), Positives = 98/289 (33%), Gaps = 30/289 (10%)

Query: 522  TPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQ 581
            TP  P    + PP  +     T  P     T T    T     P    T T PP    P 
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPIT--TTTTPPPTTTPS 1455

Query: 582  LRVYQGVTNP-TPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKH 640
              +    T P T          SP  T        T TP PTT     +PP  T ++P  
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTT---PSPPTTTPITPPA 1512

Query: 641  PEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMT----TAPPPGHP 696
               TLP      T     T  T  P     T +P + T + P T+  T    T P P   
Sbjct: 1513 STTTLP---PTTTPSPPTTTTTTPPPTT--TPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1567

Query: 697  EVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAII 756
              T PP     +  +     T  P    +T TT P T   PSP T  T+T PP       
Sbjct: 1568 TTTTPPPTTTPSPPT-----TTTPSPPTITTTTPPPTTT-PSPPTTTTTTPPP----TTT 1617

Query: 757  PEPTTETG-----HSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPA 800
            P P T T       +T L  TT P P    T     T    PPT   P+
Sbjct: 1618 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1666



 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 157/697 (22%), Positives = 213/697 (30%), Gaps = 113/697 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 3660 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 3715

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 3716 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3759

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 3760 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3810

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 3811 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3865

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3866 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3921

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3922 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3981

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3982 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 4035

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 4036 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 4082

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 4083 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 4131

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDL 751
                  VT  P+  G          T  P    +T TT  T    P+PT  +T T  P  
Sbjct: 4132 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTP-- 4177

Query: 752  GLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYT 811
                I   TT T   T     T P P    T   +    + PP E    Q S   S   T
Sbjct: 4178 ----ITTTTTVTPTPTPTGTQTGP-PTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLT 4232

Query: 812  QNKALTA---PEEHKAST---STNICELCTCGDEMLS 842
            ++  L +   P     ST   ST      T G   LS
Sbjct: 4233 ESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLS 4269



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 167/745 (22%), Positives = 225/745 (30%), Gaps = 111/745 (14%)

Query: 186  STDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQ 245
            +T T  P +  P   + +   P P+    P      P T  P       ++      P+ 
Sbjct: 1443 TTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP 1502

Query: 246  LPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVE 305
                    P+S     P   P     + T P    +  PP            T+ P    
Sbjct: 1503 PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPP---- 1558

Query: 306  VTITSEPTNETESSQAQQETPIQFPEEVEPS----ATQQEAPIEPPVPPMEHELSISEQQ 361
             T T  P   T ++     TP   P    PS     T    P   P PP     +     
Sbjct: 1559 -TTTPSPPPTTTTTPPPTTTPSP-PTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT 1616

Query: 362  QPVQPSESPREVESSPTQ---QETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQ 418
             P  P+ +P    +S T      TP  PP     T +PP          P+ +  PP   
Sbjct: 1617 TPSPPTTTPITPPTSTTTLPPTTTPSPPPT---TTTTPP----------PTTTPSPPTT- 1662

Query: 419  LTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQET 478
                  PS  + T+      TT  S       PP      P      S           T
Sbjct: 1663 ----TTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSST 1718

Query: 479  SFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSH 538
            +  SP P     PSPT   +    P T        T   +P  T   P  +   PP  S 
Sbjct: 1719 TTPSPPPTTMTTPSPTTTPS----PPTTTMTTLPPTTTSSPLTTTPLPPSIT--PPTFSP 1772

Query: 539  LTQATVQP-----------LDLGFTITPESKTEVEL---------SPTMKETPTQPPKKV 578
             +  T              LD G     +   + EL         +  +    T  P   
Sbjct: 1773 FSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVP 1832

Query: 579  VPQLRVYQGVTNPTPG-----QDQAQHPVSP-------SVTVQLLDLGLTITPEPTTEVG 626
            + QL     V + + G     +DQ    V P        + VQ  +     T   TT   
Sbjct: 1833 IGQLG-QTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTE 1891

Query: 627  HSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTAL 686
            + TPP  T ++        P P   QT        T  P+    T+TP   T     T  
Sbjct: 1892 NPTPPTTTPITTTTTVTPTPTPTGTQT-------PTTTPITTTTTVTP---TPTPTGTQT 1941

Query: 687  MTTAPPPGHPEVTLPPSDKGQAQHSH---LTQATVQPLDLEL---TITTKP---TTEVKP 737
             TT P      VT  P+  G    +     T  TV P        T TT P   TT V P
Sbjct: 1942 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2001

Query: 738  SPT---TEETSTQPPDLGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH--- 784
            +PT   T+  +T P      + P PT   T+T  +T +  TT     P P   QT     
Sbjct: 2002 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2061

Query: 785  -RSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSC 843
              + T VT  PT       +     + T       P   +  T+T I    T        
Sbjct: 2062 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-------- 2113

Query: 844  IDLNPEQRLRQVPVPEPNTHNGTFT 868
            +   P     Q P   P T   T T
Sbjct: 2114 VTPTPTPTGTQTPTTTPITTTTTVT 2138



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2004 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2059

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2060 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2103

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2104 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2154

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2155 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2209

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2210 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2265

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2266 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2325

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2326 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2379

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2380 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 2426

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 2427 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 2475

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 2476 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 2523

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 2524 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2583

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 2584 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 2635

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 2636 PITTTTTVT 2644



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2119 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2174

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2175 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2218

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2219 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2269

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2270 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2324

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2325 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2380

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2381 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2440

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2441 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2494

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2495 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 2541

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 2542 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 2590

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 2591 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 2638

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 2639 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2698

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 2699 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 2750

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 2751 PITTTTTVT 2759



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2234 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2289

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2290 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2333

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2334 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2384

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2385 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2439

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2440 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2495

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2496 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2555

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2556 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2609

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2610 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 2656

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 2657 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 2705

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 2706 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 2753

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2813

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 2814 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 2865

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 2866 PITTTTTVT 2874



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2349 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2404

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2405 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2448

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2449 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2499

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2500 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2554

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2610

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2611 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2670

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2671 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2724

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2725 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 2771

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 2772 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 2820

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 2821 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 2868

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 2869 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2928

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 2929 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 2980

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 2981 PITTTTTVT 2989



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2464 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2519

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2520 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2563

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2564 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2614

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2615 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2669

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2670 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2725

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2726 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2785

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2786 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2839

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2840 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 2886

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 2887 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 2935

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 2936 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 2983

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 2984 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3043

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3044 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3095

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3096 PITTTTTVT 3104



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2579 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2634

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2635 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2678

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2679 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2729

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2730 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2784

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2785 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2840

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2841 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2900

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2901 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2954

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2955 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3001

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3002 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3050

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 3051 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3098

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3099 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3158

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3159 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3210

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3211 PITTTTTVT 3219



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2694 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2749

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2750 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2793

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2794 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2844

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2845 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2899

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2900 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2955

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2956 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3015

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3016 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3069

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 3070 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3116

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3117 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3165

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 3166 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3213

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3214 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3273

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3274 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3325

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3326 PITTTTTVT 3334



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2809 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2864

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2865 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2908

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2909 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2959

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2960 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3014

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3070

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3071 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3130

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3131 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3184

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 3185 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3231

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3232 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3280

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 3281 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3328

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3329 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3388

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3389 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3440

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3441 PITTTTTVT 3449



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2924 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2979

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2980 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3023

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 3024 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3074

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 3075 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3129

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3130 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3185

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3186 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3245

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3246 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3299

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 3300 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3346

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3347 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3395

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 3396 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3443

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3444 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3503

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3504 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3555

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3556 PITTTTTVT 3564



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 3039 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 3094

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 3095 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3138

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 3139 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3189

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 3190 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3244

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3245 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3300

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3301 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3360

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3361 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3414

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 3415 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3461

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3462 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3510

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 3511 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3558

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3559 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3618

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3619 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3670

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3671 PITTTTTVT 3679



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 3154 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 3209

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 3210 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3253

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 3254 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3304

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 3305 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3359

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3360 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3415

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3416 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3475

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3476 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3529

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 3530 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3576

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3577 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3625

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 3626 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3673

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3674 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3733

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3734 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3785

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3786 PITTTTTVT 3794



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 161/734 (21%), Positives = 225/734 (30%), Gaps = 120/734 (16%)

Query: 167  TRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQN 226
            T   +T ++         ++T T  P   P   +  +  P   +  V P+       TQ 
Sbjct: 1884 TMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQT 1941

Query: 227  PETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPG 286
            P T             P      +   P+    + P   P ++  ++T        Q P 
Sbjct: 1942 PTT------------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP- 1988

Query: 287  EDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP 346
                       T  P     T+T  PT     +Q    TPI     V P+ T       P
Sbjct: 1989 -----------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-P 2034

Query: 347  PVPPMEHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPP 397
               P+    +++    P     P+ +P    ++      PT  +TP   P     TV+P 
Sbjct: 2035 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP- 2093

Query: 398  GHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHG 457
                T            P    T         GT    Q  TT    +   V P     G
Sbjct: 2094 ----TPTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTG 2145

Query: 458  G--PPLLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEG 509
               P   P  ++    P      T   +  PI         P+PT  +     P T    
Sbjct: 2146 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2205

Query: 510  ESSL---THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPT 566
             +     T  + P  TP      V   P  +     T  P+    T+TP        +PT
Sbjct: 2206 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPT 2259

Query: 567  MKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVG 626
              +TPT  P      +        PTP     Q P +  +T        T+TP PT   G
Sbjct: 2260 GTQTPTTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TG 2306

Query: 627  HSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTAL 686
              TP    I +      T P P   QT        T  P+    T+TP   T     T  
Sbjct: 2307 TQTPTTTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQT 2355

Query: 687  MTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-S 745
             TT P      VT  P+  G          T  P    +T TT  T    P+PT  +T +
Sbjct: 2356 PTTTPITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPT 2403

Query: 746  TQPPDLGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPP 794
            T P      + P PT   T+T  +T +  TT     P P   QT       + T VT  P
Sbjct: 2404 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2463

Query: 795  TELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQ 854
            T       +     + T       P   +  T+T I    T        +   P     Q
Sbjct: 2464 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQ 2515

Query: 855  VPVPEPNTHNGTFT 868
             P   P T   T T
Sbjct: 2516 TPTTTPITTTTTVT 2529



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 160/745 (21%), Positives = 226/745 (30%), Gaps = 94/745 (12%)

Query: 170  LSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPET 229
            ++TP     T     +ST T  P + P      +  PP  +    PS       T  P T
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTT---PSPPITTTTTPPPTT 1452

Query: 230  LEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQ 289
                  S+     P   P      P +     P   P     + T P    +  PP    
Sbjct: 1453 TPSPPISTTTTPPPTTTPS-----PPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507

Query: 290  -----AYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPI 344
                 +   LP  T        T T  PT           TP      + P+ T    P 
Sbjct: 1508 ITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1567

Query: 345  EPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHH 404
                PP       +    P   + SP  + ++     T   PP     T +PP    T  
Sbjct: 1568 TTTTPP-----PTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPT--TTTTTPP--PTTTP 1618

Query: 405  LASPSVSVKPPDVQLTI--AAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLL 462
                +  + PP    T+     PS    T+      TT          PP      PP+ 
Sbjct: 1619 SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT--------PSPPTTTTPSPPIT 1670

Query: 463  PESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQT 522
              ++           T+  SP       PSPT   ++   P T     SS T    P  T
Sbjct: 1671 TTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSS---PITTTTTPSSTTTPSPPPTT 1727

Query: 523  PEFPNVVVAQPPEHSHLT--QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVP 580
               P+      P  + +T    T     L  T  P S T    SP    TPT P    VP
Sbjct: 1728 MTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTP---CVP 1784

Query: 581  QLRVYQGVTNPTP------GQDQAQHPVSPSVTVQLLDLGLTITPE-PTTEVGHSTPPKR 633
                   + +  P      G  +    V        +    T+ P+ P  ++G +     
Sbjct: 1785 LCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDV 1844

Query: 634  TI-----VSPKHPEVTLPHPDQVQTQ-HSHLTRATVQPLDLGFTIT----PKSMTEVEPS 683
            ++        + P   +P    +  + +        QP  +  T T    P + T +  +
Sbjct: 1845 SVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTT 1904

Query: 684  TALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLEL---TITTKP---TTEVKP 737
            T +  T  P G    T  P           T  TV P        T TT P   TT V P
Sbjct: 1905 TTVTPTPTPTGTQTPTTTPI---------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1955

Query: 738  SPT---TEETSTQPPDLGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH--- 784
            +PT   T+  +T P      + P PT   T+T  +T +  TT     P P   QT     
Sbjct: 1956 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2015

Query: 785  -RSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSC 843
              + T VT  PT       +     + T       P   +  T+T I    T        
Sbjct: 2016 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-------- 2067

Query: 844  IDLNPEQRLRQVPVPEPNTHNGTFT 868
            +   P     Q P   P T   T T
Sbjct: 2068 VTPTPTPTGTQTPTTTPITTTTTVT 2092



 Score = 39.7 bits (91), Expect = 0.025
 Identities = 33/111 (29%), Positives = 44/111 (39%), Gaps = 10/111 (9%)

Query: 720  PLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDR 779
            P+D  +T  + PTT   P PT+  T+T PP       P P T T  +T    TT P P  
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTS--TTTLPP----TTTPSPPTTT--TTTPPPTTTPSPPI 1442

Query: 780  VQTLHRSLTEVTGPP--TELEPAQDSLVQSESYTQNKALTAPEEHKASTST 828
              T     T    PP  T   P   +     + T +   T P     +T+T
Sbjct: 1443 TTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTT 1493


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 177/748 (23%), Positives = 276/748 (36%), Gaps = 135/748 (18%)

Query: 118 EQPLEPEQFLASQQD----LKDKLSPQERLPVSPK-KLKKDPAQRWSLAEIIGITRQLST 172
           E+ + PE+  A  ++    L + +   E  P  P  +LK D +Q+ S     G    ++ 
Sbjct: 89  EETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQLKMDRSQQTSRT---GYWTMMNI 145

Query: 173 PQSQK-QTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGP----SQFHLEPETQNP 227
           P  +K    Q  Y S       S P     KS E     +  G          +P T + 
Sbjct: 146 PPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSN 205

Query: 228 ETL--EDIQSSSLQQEAPAQLPQLLEEEPSS-----MQQEAPALPPESSMESLTLPNHE- 279
           E +  ++I  +S  QE     P LLE+E        + QE  A+   +S E +  P+ E 
Sbjct: 206 EEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAE-IEPPSTEK 264

Query: 280 --VSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPI--QFPEEVEP 335
               +QPP  ++A         +   V+V  ++E T + E++ A  E  +  Q P   E 
Sbjct: 265 FPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEA 324

Query: 336 SATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVS 395
              +  A I+PP       + +  +  P    ESP E    P  +  P  PP     +V 
Sbjct: 325 PLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSE---EPPAEILP--PPAEKSPSVE 379

Query: 396 PPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQ 455
             G      + SPS    P +VQ  + AE + E        EA  +       VEPP ++
Sbjct: 380 LLGE-----IRSPSAQKAPIEVQ-PLPAEGALE--------EAPAK-------VEPPTVE 418

Query: 456 H---GGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESS 512
                  PLLPE +       +Q  T+ ++P        +PT+ ++      TAEE  + 
Sbjct: 419 ETLADVQPLLPEEAPREEARELQLSTAMETPA-----EEAPTEFQSPLPKETTAEEASA- 472

Query: 513 LTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPT 572
                      E   +   +PP      +A   PL    T   E+  EV+ SP  +ET  
Sbjct: 473 -----------EIQLLAATEPPADETPAEAR-SPLSEE-TSAEEAHAEVQ-SPLAEETTA 518

Query: 573 QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPK 632
           +     +  L   +   + TP +  AQ P+S   + +          E   EV     P 
Sbjct: 519 EEASAEIQLLAAIEAPADETPAE--AQSPLSEETSAE----------EAPAEV---QSPS 563

Query: 633 RTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTA-- 690
              VS +   + L  P   +T     + A +Q L        ++  EV+P  A    A  
Sbjct: 564 AKGVSIEEAPLELQPPSGEETTAEEAS-AAIQLLAATEASAEEAPAEVQPPPAEEAPAEV 622

Query: 691 -PPPGHP---EVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTE-ETS 745
            PPP      EV  PP+++  A+        VQP   E     +   EV+P P  E    
Sbjct: 623 QPPPAEEAPAEVQPPPAEEAPAE--------VQPPPAE-----EAPAEVQPPPAEEAPAE 669

Query: 746 TQPP---DLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSL--------------- 787
            QPP   +    +   P  ET     L    +P  D V     S+               
Sbjct: 670 VQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEF 729

Query: 788 ------TEVTGPPTELEPAQDSLVQSES 809
                  EV+ PP+E  P  ++LV++ S
Sbjct: 730 PIGEASAEVSPPPSEQTPEDEALVENVS 757



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 86/339 (25%), Positives = 132/339 (38%), Gaps = 59/339 (17%)

Query: 92  SSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLK 151
           S+ M  P +E+       L    +A E   E  Q LA+ +   D+   + R P+S +   
Sbjct: 443 STAMETPAEEAPTEFQSPLPKETTAEEASAEI-QLLAATEPPADETPAEARSPLSEETSA 501

Query: 152 KD-------PAQRWSLAEIIGITRQL---------STPQSQKQTLQNEYSSTDTPYPGSL 195
           ++       P    + AE      QL          TP   +  L  E S+ + P     
Sbjct: 502 EEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQS 561

Query: 196 PPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQL-PQLLEEEP 254
           P    V  +E P   +     +   E  +   + L   ++S+  +EAPA++ P   EE P
Sbjct: 562 PSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASA--EEAPAEVQPPPAEEAP 619

Query: 255 SSMQ----QEAPA--LPP---ESSMESLTLPNHEV--SVQPPGEDQAYYHLPNITVKPAD 303
           + +Q    +EAPA   PP   E+  E    P  E    VQPP  ++A          PA+
Sbjct: 620 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEA----------PAE 669

Query: 304 VEVTITSEPTNETESSQAQQETPIQF--------PEEVEPSATQQEAPIEPPVPP----M 351
           V+     E   E +S  A +ETPI+         P +  P+   +EA ++   PP    +
Sbjct: 670 VQPPPAEEAPAEVQSLPA-EETPIEETLAAVHSPPADDVPA---EEASVDKHSPPADLLL 725

Query: 352 EHELSISEQQQPVQ--PSESPREVESSPTQQETPGQPPE 388
             E  I E    V   PSE   E E+      T  Q P+
Sbjct: 726 TEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQ 764


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 139/675 (20%), Positives = 242/675 (35%), Gaps = 122/675 (18%)

Query: 132   DLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPY 191
             ++ +K+ P ++ P      K+ PA+   + + I +  ++  P+  +           T  
Sbjct: 10444 EISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVP--------PTKV 10495

Query: 192   PGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLE 251
             P  LPP+  V   + P P  +        +PE   P+  E  +    +++ P   P+  E
Sbjct: 10496 PEVLPPKEVVPEKKVPVPPAK--------KPEAPPPKVPEAPKEVVPEKKVPVPPPKKPE 10547

Query: 252   EEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADV--EVTIT 309
               P+ + +   A  PE  +     P  E    PP         P +   P +V  E  + 
Sbjct: 10548 VPPTKVPEVPKAAVPEKKVPEAIPPKPE---SPP---------PEVPEAPKEVVPEKKVP 10595

Query: 310   SEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPP----VPPME----HELSISEQQ 361
             + P  + E       TP++ PE  +    +++ P+ PP    VPP +     ++++ E++
Sbjct: 10596 AAPPKKPEV------TPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKK 10649

Query: 362   Q----PVQPSESPREVESSPTQ---QETPGQPPEHHEVTVSP----PGHHQTHHLASPSV 410
                  P +P   P EV   P +   +E P +  E  E    P    P         +P+V
Sbjct: 10650 VPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAV 10709

Query: 411   SVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPE------ 464
               K P++      E   EV    V ++    +     +  P  +      ++PE      
Sbjct: 10710 VAKKPELPPVKVPEVPKEV----VPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVP 10765

Query: 465   SSEEAGPLAVQQETSFQSPEPINNENPS-PTQQEAAAEHPQTAEEGESSLTHQE------ 517
                E  P  V +       +P+  E P+ P  + A +  P+  EE E     +E      
Sbjct: 10766 KKPEVPPAKVPEVPK----KPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEE 10821

Query: 518   -----APAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPT 572
                  A  + PE P   V + P+                 I PE K      P +K+   
Sbjct: 10822 KPVPVAEEEEPEVPPPAVPEEPK----------------KIIPEKKV-----PVIKKPEA 10860

Query: 573   QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPK 632
              PPK+  P+  + +    P P       P  P   V+     L   P+         P K
Sbjct: 10861 PPPKEPEPEKVIEKPKLKPRP---PPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEK 10917

Query: 633   RTIVSPKHP----EVTLPHPDQVQTQHSHLTRATV---QPLDLGFTITPKSMTEVEPSTA 685
               +   K P    +V    P++       +   +V   +P +    + PK + +V+   A
Sbjct: 10918 VELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVK-KPA 10976

Query: 686   LMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETS 745
             +    PP    EV +P   K + +    T+       + L     P  E KP P  E  +
Sbjct: 10977 VPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPL-----PAPEPKPKPEAEVKT 11031

Query: 746   TQPPDLGLAIIPEPT 760
              +PP     + PEPT
Sbjct: 11032 IKPP----PVEPEPT 11042



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 161/792 (20%), Positives = 274/792 (34%), Gaps = 99/792 (12%)

Query: 122   EPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQ 181
             E E+F+  ++ L + + P+  +P    ++KK   ++      + I ++   P ++   + 
Sbjct: 10163 EEEEFVPEEEVLPE-VKPKVPVPAPVPEIKKKVTEKK-----VVIPKKEEAPPAKVPEVP 10216

Query: 182   NEYSSTDTPYPGS---LPPELRVKSDEPPGPSEQVG--PSQFHLEPETQNPETLEDIQSS 236
              +        P     LP E+  + +E P   E++   P       E   P   E I+ +
Sbjct: 10217 KKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKA 10276

Query: 237   SLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPN 296
                 EAP  +P+ +E  P+ + ++ P       ++    P  +V   P    +    +P 
Sbjct: 10277 V--PEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPK 10334

Query: 297   ITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEP-SATQQEAPIEPPVPPME--- 352
                 P     T+  E      S   +QE  ++   E+E   A  +E P E     +E   
Sbjct: 10335 KEAVPPAKGRTVLEEKV----SVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYF 10390

Query: 353   -----HELS--ISEQQQPVQPSESPREV-------ESSPTQQ-ETPGQPPEHHEVT--VS 395
                  HE+   I  +Q  V+      +V       E+   +  E P  PP+  E++  + 
Sbjct: 10391 EEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKII 10450

Query: 396   PPGHHQTHHLASPSVSVKPPDVQLTIAAE-----------PSAEVGTSLVHQEATTRLSG 444
             PP    T  +       K P+V   I  E           P  +V   L  +E       
Sbjct: 10451 PPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKV 10510

Query: 445   SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAA-AEHP 503
                 V P       PP +PE+ +E  P     E     P P   E P     E   A  P
Sbjct: 10511 P---VPPAKKPEAPPPKVPEAPKEVVP-----EKKVPVPPPKKPEVPPTKVPEVPKAAVP 10562

Query: 504   QTAEEGESSLTHQEAPAQTPEFPNVVV------AQPPEHSHLTQATVQPLDLGFTITPES 557
             +           +  P + PE P  VV      A PP+   +T   V   +    + PE 
Sbjct: 10563 EKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVP--EAPKEVVPEK 10620

Query: 558   KTEVELSPTMKETPT---QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPS-VTVQLLDL 613
             K  V      +  PT   + PK  VP+ +V + +  P P     +    P  V ++    
Sbjct: 10621 KVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIP-PKPESPPPEVFEEPEEVALEEPPA 10679

Query: 614   GLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTI- 672
              +   PEP      + PPK+ +   K P V    P+    +   + +  V    +   + 
Sbjct: 10680 EVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVP 10739

Query: 673   ---------TPKSMTEVEPSTALMTT----APPPGHPEVTLPPSDKGQAQHSHLTQATVQ 719
                       P+   EV P   +        PP   PEV   P  + +       +A   
Sbjct: 10740 KKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESP 10799

Query: 720   PLDL-ELTITTKPTTEV-----KPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTT 773
             P ++ E      P  E+     KP P  EE   + P   +   P+          ++K  
Sbjct: 10800 PPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPE 10859

Query: 774   AP---RPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL---TAPEEHKASTS 827
             AP    P+  + + +   +   PP    P ++ +   E   Q KA+     PE+ +    
Sbjct: 10860 APPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDV--KEKIFQLKAIPKKKVPEKPQVPEK 10917

Query: 828   TNICELCTCGDE 839
               +  L   G E
Sbjct: 10918 VELTPLKVPGGE 10929



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 124/598 (20%), Positives = 209/598 (34%), Gaps = 97/598 (16%)

Query: 34    VKEAQPLEWVKDPLQLTSNPLGPPESWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASS 93
             V E  P + V    ++   P   PE+        P+E      +P  P     + P+   
Sbjct: 10495 VPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVP 10554

Query: 94    EMP------------------APPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKD 135
             E+P                  +PP E  E     +         P +PE       +   
Sbjct: 10555 EVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPK 10614

Query: 136   KLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL-QNEYSSTDTPYPGS 194
             ++ P++++PV P K  + P  +               P+  K  + + +      P P S
Sbjct: 10615 EVVPEKKVPVPPPKKPEVPPTK--------------VPEVPKVAVPEKKVPEAIPPKPES 10660

Query: 195   LPPEL-----RVKSDEPPG----PSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQ 245
              PPE+      V  +EPP       E   P Q  + P+   PE       +   +  P +
Sbjct: 10661 PPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVK 10720

Query: 246   LPQLLEE-------------EPSSMQQEAPALPPESSMESLTLPNHEVSVQ-----PPGE 287
             +P++ +E             +P +   + P +P E       +P  +V+V      PP +
Sbjct: 10721 VPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKE------VVPEKKVAVPKKPEVPPAK 10774

Query: 288   DQAYYHLPNITVKPA-DVEVTITSEPTNETESSQ--AQQETPIQFPEEVEPSATQQEAPI 344
                    P +  KPA  V     S P    E  +  A +E      E+  P A ++E  +
Sbjct: 10775 VPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEV 10834

Query: 345   EPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHH 404
              PP  P E +  I E++ PV      ++ E+ P ++  P +  E  ++   PP       
Sbjct: 10835 PPPAVPEEPKKIIPEKKVPV-----IKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPP--- 10886

Query: 405   LASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPE 464
              A P   VK    QL    +        +  +   T L   G + +   ++   P   PE
Sbjct: 10887 -APPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKK---VRKLLPERKPE 10942

Query: 465   SSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAE--HPQTAEEGE-SSLTHQE---- 517
               EE    +V ++   +    +  +     ++ A  E   P+  EE E  ++T +E    
Sbjct: 10943 PKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIP 11002

Query: 518   APAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPP 575
              P + PE    +    PE     +A V+      TI P     VE  PT    P   P
Sbjct: 11003 EPTKVPEIKPAIPLPAPEPKPKPEAEVK------TIKP---PPVEPEPTPIAAPVTVP 11051



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 145/720 (20%), Positives = 254/720 (35%), Gaps = 88/720 (12%)

Query: 123   PEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQT-LQ 181
             PE+ + +    K+K+ P    P  P++ KK   ++    ++I +   L    +++   + 
Sbjct: 9589  PEKKVPAPVPKKEKVPP----PKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQIT 9644

Query: 182   NEYSSTDTPYPGSLPPELRVKSDEPPG-PSEQVGPSQFHLEP--ETQNPETLEDIQSSSL 238
              E            PP+ RV  +     P E+V      L+P  E + P  + + +   +
Sbjct: 9645  QEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKV----LKLKPKREEEPPAKVTEFRKRVV 9700

Query: 239   QQE-----APAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYH 293
             ++E     AP + PQ ++E     ++E           + TL    VSVQ   E + Y  
Sbjct: 9701  KEEKVSIEAPKREPQPIKEVTIMEEKE----------RAYTLEEEAVSVQREEEYEEY-- 9748

Query: 294   LPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEH 353
                   +  D +     EPT E +  +  +E   +  EE E   T+ E PI  PV P   
Sbjct: 9749  ------EEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPI--PVKP--- 9797

Query: 354   ELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVK 413
                + E+  P +P   P +V      +E    P         P    +   +    + + 
Sbjct: 9798  ---VPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRIS 9854

Query: 414   PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPA-IQHGGPPLLPE--SSEEAG 470
                 +     EP+A+V        A  ++     +V PP  +      L PE  + EE  
Sbjct: 9855  ITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEV 9914

Query: 471   PLAVQQETSFQSPEPINNENPSPTQQEAAAEHP-QTAEEGESSLTHQEAPAQTPEFPNVV 529
                V++    +  E I+ E    T++E     P +  E     +  ++ P   P+     
Sbjct: 9915  VTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAP 9974

Query: 530   VAQPPEHSHLTQATVQPL-------------DLGFTITPESKTEVELSPTMKETPT---Q 573
              A+ PE     +  V  L             ++     PE K  V +   ++  P    +
Sbjct: 9975  PAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPE 10034

Query: 574   PPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP-TTEVGHSTPPK 632
              PKK VP+ +    V  P P + +A     P V  +L+      TP P   E      PK
Sbjct: 10035 VPKKPVPEKK----VPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPK 10090

Query: 633   RTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPP 692
             +    P    V LP  ++V  +   +    V P +       + +   E          P
Sbjct: 10091 KR--EPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIP 10148

Query: 693   PGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET----STQP 748
             P   EV  P  +    +   + +  V P          P  E+K   T ++       + 
Sbjct: 10149 PEEEEVP-PEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEA 10207

Query: 749   PDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSE 808
             P   +  +P+   E       ++   P+ + V  +     EVT  P E EP  +  +  E
Sbjct: 10208 PPAKVPEVPKKVEE-------KRIILPKEEEVLPV-----EVTEEPEE-EPISEEEIPEE 10254



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 106/504 (21%), Positives = 189/504 (37%), Gaps = 71/504 (14%)

Query: 114   DSAGEQPLEPEQFLASQQDL--KDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLS 171
             + A + P++P++ +A ++    + +++P  R+P  PK+L  +P +     E++    +  
Sbjct: 9865  EPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKEL--EPEEVAFEEEVVTHVEEYL 9922

Query: 172   TPQSQKQTLQNEYSSTDTPYPGSLP------PELRVKSDEPPGPSEQVGPSQFHLEPET- 224
               + ++   + E   T+      +P      P   V  ++ P P  +   +     PE  
Sbjct: 9923  VEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVP 9982

Query: 225   QNPETLEDIQSSSLQQEAPAQLPQL----LEEE----PSSMQQEAP-ALPPESSMESLTL 275
             + PE    +     ++  PA++P++    + EE    P   + EAP A  PE  +    +
Sbjct: 9983  KKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPE--VPKKPV 10040

Query: 276   PNHEVSVQPPGEDQA----YYHLPNITV----KPADVEVTITSEPTNETESSQAQQETPI 327
             P  +V V  P + +A       +P   +    KP  V   + + P  +    +     P+
Sbjct: 10041 PEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPP-KVPKKREPVPVPV 10099

Query: 328   QFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQP- 386
               P+E E    ++  P E  +P  E  L   E+  P +    P E E  P ++E P +  
Sbjct: 10100 ALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEE 10159

Query: 387   --PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSG 444
               PE  E                P   V P          P  E+   +  ++       
Sbjct: 10160 YVPEEEEFV--------------PEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVI---- 10201

Query: 445   SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQ 504
                +  PPA      P +P+  EE   + + +E      E        P  +E   E P 
Sbjct: 10202 PKKEEAPPA----KVPEVPKKVEEK-RIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPP 10256

Query: 505   TAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELS 564
             + EE E     + AP + PE     V + P  + + +    P        PE K  V + 
Sbjct: 10257 SIEEVE-----EVAPPRVPEVIKKAVPEAP--TPVPKKVEAPPAKVSKKIPEEKVPVPVQ 10309

Query: 565   PTMKETP----TQPPKKVVPQLRV 584
                KE P     + PKK VP+ +V
Sbjct: 10310 --KKEAPPAKVPEVPKK-VPEKKV 10330



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 77/377 (20%), Positives = 135/377 (35%), Gaps = 61/377 (16%)

Query: 44    KDPLQLTSNPLGPPESWSSHSSHF-PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQES 102
             K PL +   P  PP           P +    P  P  P       P+   E+P  P   
Sbjct: 10733 KVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVP-------PAKVPEVPKKPVLE 10785

Query: 103   TENLVPFLDTWDSAG----EQPLE--PEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQ 156
              +  VP  +  +S      E+P E  PE+ +A +++    ++ +E   V P  + ++P +
Sbjct: 10786 EKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKK 10845

Query: 157   RWSLAEIIGITRQLSTPQSQ---KQTLQNEYSSTDTPYPGSLPPELRVKS---------- 203
                  ++  I +  + P  +   ++ ++        P P   PP+  VK           
Sbjct: 10846 IIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPK 10905

Query: 204   ----DEP-------------PGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQL 246
                 ++P             PG  ++V       +PE +    L+ +     ++E P   
Sbjct: 10906 KKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVE 10965

Query: 247   PQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEV 306
             P+ LE+       E P   P   +E  T+   E  +  P +      +P I  KPA    
Sbjct: 10966 PKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTK------VPEI--KPAIPLP 11017

Query: 307   TITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQ--QPV 364
                 +P  E E    +       P  VEP  T   AP+  PV   + E    +++  +P 
Sbjct: 11018 APEPKPKPEAEVKTIK-------PPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPK 11070

Query: 365   QPSESPREVESSPTQQE 381
              P +   +   SP + E
Sbjct: 11071 GPIKGVPKKTPSPIEAE 11087



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 104/539 (19%), Positives = 196/539 (36%), Gaps = 93/539 (17%)

Query: 176  QKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQS 235
            +++ +Q +    +  +   +P ++  K   PP P     P    +E  ++  E  E +Q 
Sbjct: 9146 EREVIQVQKEVYEESHERKVPAKVPEKKAPPP-PKVIKKPVIEKIEKTSRRMEE-EKVQV 9203

Query: 236  SSLQQEAPAQLPQLLEEEPSS---MQQEAPALPPES---SMESLTLPNH---EVSVQPPG 286
            + + + +   +PQ     P     ++ + PA+  +    S E +   +H   EVSV  P 
Sbjct: 9204 TKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPE 9263

Query: 287  EDQAYYHLPNITVKPADVEVTITSEPTNET----ESSQAQQETPIQFPEEVEPSATQQEA 342
              +       +T +   V ++   EP  +     E    ++  P+  P++VEP A +   
Sbjct: 9264 VQKEI-----VTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPE 9318

Query: 343  PIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQE------------TPGQPPE-- 388
              + PVP  +  + +  +++P  P + P EV   P  +E             P + PE  
Sbjct: 9319 VPKKPVPEEKKPVPV-PKKEPAAPPKVP-EVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQ 9376

Query: 389  -----HHEVTV-------SPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA-EVGTSLVH 435
                   ++T+        PP   +      P      P  +  +   P    +    V 
Sbjct: 9377 KGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVP 9436

Query: 436  QEATTRLSGSGNDVEPPAIQHGGPPLLPES---SEEAGPLAVQQETSFQSPEPINNENPS 492
            +E             PP  +     ++ E    +EE    AV Q       E    E  S
Sbjct: 9437 EEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWS 9496

Query: 493  PTQQE-----AAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPL 547
             +++E     +     +  EE E+ +T  E   +  E+    V +   H    +   +P 
Sbjct: 9497 YSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEY----VVEEKLHIISKRVEAEPA 9552

Query: 548  DL------GFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP 601
            ++         + P+   ++E  P  K    + PKK+VP+ +    V  P P +++   P
Sbjct: 9553 EVTERQEKKIVLKPKIPAKIEEPPPAK--VPEAPKKIVPEKK----VPAPVPKKEKVPPP 9606

Query: 602  VSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
              P               EP   V    P K+  V PK  ++  P P +V  +H  +T+
Sbjct: 9607 KVPE--------------EPKKPV----PEKK--VPPKVIKMEEPLPAKVTERHMQITQ 9645


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 125/521 (23%), Positives = 172/521 (33%), Gaps = 77/521 (14%)

Query: 382  TPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTR 441
            +PG PP           H  T     P    +PP    T  A P+   G S         
Sbjct: 969  SPGSPPTLRV-------HGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPS--------- 1012

Query: 442  LSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSP--TQQEAA 499
               S     P         L P S+  +   +   +TS  +P+P +  NP    T  + A
Sbjct: 1013 --ASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFA 1070

Query: 500  AEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT-------QATVQPLDLGFT 552
               P ++     +LT + +P   P  P  + + P   S +T       Q           
Sbjct: 1071 LSTPDSSVV--PALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLD 1128

Query: 553  ITPESKTEVELS----------PTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPV 602
             TP S T  E S          PT    PT  P  +             TP      HP 
Sbjct: 1129 TTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPT 1188

Query: 603  SPSVTVQLLDLGLTITPEPTTEVGHST---------PPKRTIVSPKHPEVTLPHPDQVQT 653
            + + +  + D   T TP+P T + HST          P  T+     P  T PHP    T
Sbjct: 1189 TITHSTMIPDP--TTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHP----T 1242

Query: 654  QHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHL 713
               H T  T   +    T TP+  T ++P+T    T  P  HP  T  P+        H 
Sbjct: 1243 TTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTP--HPTTTPHPTTT-----PHP 1295

Query: 714  TQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTT 773
            T      +  + T T  PTT   P PTT    T P      +I   +  T   T L   T
Sbjct: 1296 TTTPHPTMTPDPTTTPYPTTT--PDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPT 1353

Query: 774  APRPDRVQTLHRSLTEVTG---------PPTELEPAQDSLVQSESYTQNKALTAPEEHK- 823
               P    +LH  LT             P  E  PA +S     S   +    + E+ K 
Sbjct: 1354 L-APTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKP 1412

Query: 824  -ASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTH 863
              S S N+    T      S + ++P+  L   P   P  H
Sbjct: 1413 PRSQSPNLTPPPTHTPHSASDLTVSPDPLLS--PTAHPLDH 1451



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 132/576 (22%), Positives = 195/576 (33%), Gaps = 98/576 (17%)

Query: 165  GITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPET 224
            G TR   +P + +  +  +  S   P+P   PP        PP PS     S     P  
Sbjct: 965  GTTRSPGSPPTLR--VHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGPPGPAL 1022

Query: 225  QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP 284
             +  + E    S+L  EA +  P      P    +  P L   S   +L+ P+  V    
Sbjct: 1023 TSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSV---- 1078

Query: 285  PGEDQAYYHLPNITVKPADVEV-TITSEPTNETESSQAQQETPIQFPEEVEP-SATQQEA 342
                     +P +T +P+   + T+  E T++  +           P EV   S T ++ 
Sbjct: 1079 ---------VPALTPEPSPTPLPTLPKELTSDPST-----------PSEVTSLSPTSEQV 1118

Query: 343  PIEPPVPPME---HELSISEQQQPVQPSESPREVES-SPTQQE----------TPGQPPE 388
            P     P ++   +  ++SE  +   PS SP    +  PT             TP  P  
Sbjct: 1119 PESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTT 1178

Query: 389  HHEVTVSPPGHHQTHHLASPSVSVKPPD----VQLTIAAEPSAEVGTSLVHQEATTRLSG 444
             H  T +P     TH    P  +  P         T+  +P+         Q  TT  S 
Sbjct: 1179 PHP-TTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHST 1237

Query: 445  SGNDV---EPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAE 501
            + +      P  I H    ++P+ +    P    Q T+   P P    +P+ T       
Sbjct: 1238 TPHPTTTPHPTTITHS--TMIPDPTTTPQPFTTMQPTTM--PHPTTTPHPTTTPHPTTTP 1293

Query: 502  HPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEV 561
            HP T        T    P  TP +P      P    H T        +  T++  +    
Sbjct: 1294 HPTTTPHP----TMTPDPTTTP-YP-TTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGT 1347

Query: 562  ELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP 621
            ELS     +PT  P  V P L      T P P    +Q P              T+ P P
Sbjct: 1348 ELS-----SPTLAP-TVKPSLHPQLTFTAPAPHTSTSQIP--------------TLEPSP 1387

Query: 622  TTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTE-- 679
              E   S     T + P   E   P     ++Q  +LT           T TP S ++  
Sbjct: 1388 ALESSPSRSSTATSMDPLSTEDFKP----PRSQSPNLTPPP--------THTPHSASDLT 1435

Query: 680  VEPSTALMTTAPPPGHP---EVTLPPSDKGQAQHSH 712
            V P   L  TA P  HP    +TL P+  GQ+   H
Sbjct: 1436 VSPDPLLSPTAHPLDHPPLDPLTLGPT-PGQSPGPH 1470



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 122/602 (20%), Positives = 182/602 (30%), Gaps = 124/602 (20%)

Query: 56   PPESWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPP--QESTENLVPFLD-- 111
            P + W       P  +  AP  P+        GPSAS   P P    +S+  L P     
Sbjct: 985  PRKPWPERRPPRPAATRTAPPTPSP-------GPSASPGPPGPALTSDSSRELTPHSALT 1037

Query: 112  ---TWDSAGEQPLEPEQFLASQQDL----------------KDKLSPQER---LPVSPKK 149
               T D+    P  P+    +  DL                   L+P+     LP  PK+
Sbjct: 1038 SEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKE 1097

Query: 150  LKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGP 209
            L  DP+    +  +   + Q+    +        YSST + Y  S  P         P P
Sbjct: 1098 LTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDP------SPSPHP 1151

Query: 210  SEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESS 269
            +    P+       T NP       ++      P          P+++        P ++
Sbjct: 1152 TTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTP---------HPTTITHSTMIPDPTTT 1202

Query: 270  MESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQF 329
             +  T   H   +  P         P  T++P     + T  PT     +     T I  
Sbjct: 1203 PQPFTTITHSTMIPDPTTTPQ----PFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPD 1258

Query: 330  PEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEH 389
            P       T  +    P      H  +         P+ +P      PT    P   P  
Sbjct: 1259 PTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPH-----PTMTPDPTTTP-- 1311

Query: 390  HEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDV 449
                 + P    T H  +P  S  P    +T  + P++ +GT L                
Sbjct: 1312 --YPTTTPDPTTTPHPTTPDPSSTP---VITTVSLPTS-LGTEL---------------- 1349

Query: 450  EPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEG 509
                     P L P       P     + +F +P P  + +  PT + + A     +   
Sbjct: 1350 -------SSPTLAPTVKPSLHP-----QLTFTAPAPHTSTSQIPTLEPSPA---LESSPS 1394

Query: 510  ESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKE 569
             SS      P  T +F        P  S     T  P     T TP S +++ +SP    
Sbjct: 1395 RSSTATSMDPLSTEDF-------KPPRSQSPNLTPPP-----THTPHSASDLTVSPDPLL 1442

Query: 570  TPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHST 629
            +PT  P    P   +  G   PTPGQ    H             G  + P P   V    
Sbjct: 1443 SPTAHPLDHPPLDPLTLG---PTPGQSPGPH-------------GPCVAPTPPVRVMACE 1486

Query: 630  PP 631
            PP
Sbjct: 1487 PP 1488



 Score = 31.6 bits (70), Expect = 6.9
 Identities = 39/139 (28%), Positives = 51/139 (36%), Gaps = 36/139 (25%)

Query: 674 PKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTT 733
           PKS  +     A   T  PP      +P +   +AQ          P DL    T   TT
Sbjct: 625 PKSTKKWVTKNAKRPTTQPP-----VMPTTKHSRAQ---------SPPDLTSQTTAALTT 670

Query: 734 EVKPSPTTEETSTQPPDLGLAIIPEPTTE-----TGHSTALEKTTAPRPDRVQTLHRSLT 788
           E    PT+E T              PTTE     T H+TA     APR    +T+    T
Sbjct: 671 EASRRPTSEFTR------------RPTTEAPQRWTSHTTATLTPQAPRERTTKTMAMLTT 718

Query: 789 EVTGPPTELEPAQDSLVQS 807
           +  GP    E   +S ++S
Sbjct: 719 Q--GPQ---EMTSESTIKS 732


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 171/758 (22%), Positives = 242/758 (31%), Gaps = 140/758 (18%)

Query: 46  PLQLTSNPLGPPESWSSH-SSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTE 104
           P    + P+ PP++ ++   +  P   P A  LP  P       P +   +P+PP     
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS--APPSLQTLPSPPATPPS 366

Query: 105 NLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEII 164
              P + T        L   Q +   Q      SP  + P SP  L    A     +  +
Sbjct: 367 QAPPSMTTPPMQAPPSL---QTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL 423

Query: 165 GITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE---LRVKSDEPPGPSEQVGPSQFHLE 221
             T    T  S +QT   + S T    P S PP+   L+     P  P     P Q  L 
Sbjct: 424 QATHSFLT-MSPRQT---QASLTSPSRPASTPPDSPPLQAPLSLPASP-----PLQTSLS 474

Query: 222 PETQ---NPETLEDIQS-SSLQQEAP-AQLPQLLEEEPSSMQQEAPALPPESSMESLTLP 276
           P      +P T+  +Q+ SSL   +P A L  L+           P L  +SS+   +L 
Sbjct: 475 PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI----------MPPLETQSSLAPPSLQ 524

Query: 277 NHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQ-----QETPIQFPE 331
               S+  P  +    +LP++   P        + P  ET    A        +P+  P 
Sbjct: 525 TPPASLTTPPLE----NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP 580

Query: 332 EVEPSATQQEAPIEPPV---PPMEHELSISEQQQPVQPSESPREVESSPTQQ--ETPGQP 386
              PS+     P  PP    PP++   S         P ++P  +   P Q     P  P
Sbjct: 581 PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640

Query: 387 PEHHEVTVSP--PGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSG 444
           P     T SP  P     H L +P      P VQ   +   S  V  S     AT     
Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS-----ATPPSQA 695

Query: 445 SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQ 504
             +   PP      PP  P  S  A P         Q+P P+            AA   Q
Sbjct: 696 PPSLAAPPLQVPPSPPASPPMSPSATPPP-------QAPPPL------------AAPPLQ 736

Query: 505 TAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELS 564
                 +S     +    P  P ++ A P +                 + P     + +S
Sbjct: 737 VPPSPPASPPMSPSATPPPRVPPLLAAPPLQ-----------------VPPSPPASLPMS 779

Query: 565 PTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGL------TIT 618
           P  K  P  PP    P L   Q + +P P     Q P SPS ++ +  L         + 
Sbjct: 780 PLAKPPPQAPPALATPPL---QALPSP-PASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835

Query: 619 PEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMT 678
             P  +V  S P   T+ +P+ P    P PD                            T
Sbjct: 836 AAPLLQVPPSPPASPTLQAPRRPPT--PGPD----------------------------T 865

Query: 679 EVEPSTALMTTAPPPGHPEVTLPPSD-KGQAQHSHLTQATVQPLDLELTITTKPTTEVKP 737
            V      +  AP P  P    P S   G     H + AT  P +L              
Sbjct: 866 SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR---------GYDS 916

Query: 738 SPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAP 775
            P     ++ PPD  LA         G +  L    AP
Sbjct: 917 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 954



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 143/588 (24%), Positives = 203/588 (34%), Gaps = 100/588 (17%)

Query: 36  EAQPLEWVKDPLQLTSNPLGPPESWSSHS--SHFPRESPHAPTLPADPWDFDHLGPSASS 93
           +A P       LQ T++ LG P   ++HS  +  PR++  + T P+ P         AS+
Sbjct: 401 QAPPSPLALSSLQATTS-LGSPTLQATHSFLTMSPRQTQASLTSPSRP---------AST 450

Query: 94  EMPAPPQESTENLV--PFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLK 151
              +PP ++  +L   P L T  S    PL     +   Q L    S   + P+S   L 
Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS--SLI 508

Query: 152 KDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTP----YPGSLPPELRVKSDEPP 207
             P +  S          L+ P     +LQ   +S  TP     P   PP L+  S    
Sbjct: 509 MPPLETQS---------SLAPP-----SLQTPPASLTTPPLENLPSLAPPPLQTASAPLT 554

Query: 208 GPSEQVGPSQFHLE-PETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPP 266
            P         HLE P    P  L         Q  P+ L     E PSS+    P  PP
Sbjct: 555 TP---------HLETPPCPAPCPL---------QAPPSPLTTPPPETPSSIATPPPQAPP 596

Query: 267 ESSMESLT-LPNHEVS--VQPPGEDQAYYHLPNITVKPAD-VEVTITSEPTNETESSQAQ 322
             +   L  LP+  +S    PP +      LP +   P+      ++   T   ++  A 
Sbjct: 597 ALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNAL 656

Query: 323 QETPIQFPEEVEPSATQQ---EAPIEPPV-----PPMEHELSISE---QQQPVQPSESPR 371
               +Q P    PS   Q     P  PPV     PP +   S++    Q  P  P+  P 
Sbjct: 657 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 716

Query: 372 EVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVK----------PPDVQLTI 421
              ++P  Q  P       +V  SPP        A+P   V           PP    ++
Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776

Query: 422 AAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQ 481
              P A+         AT  L    +   PPA   G  P  P +S    PLA       Q
Sbjct: 777 PMSPLAKPPPQAPPALATPPLQALPS---PPASFPGQAPFSPSASLPMSPLATPPP---Q 830

Query: 482 SP----EPINNENPSP-------TQQEAAAEHPQTAEEGESSLTHQEAPAQTP---EFPN 527
           +P     P+    PSP         +      P T+  G   LT   AP   P     P+
Sbjct: 831 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG-PRLTLALAPGPPPPPSRSPS 889

Query: 528 VVVAQPPEHSHLTQATVQPLDL-GFTITPESKTEVELSPTMKETPTQP 574
             ++ P    H + AT  P +L G+   PE        P  +     P
Sbjct: 890 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP 937



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 147/696 (21%), Positives = 220/696 (31%), Gaps = 121/696 (17%)

Query: 138 SPQERLPVSPKKLKKDPAQ----RWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPG 193
           SP+   PV+P  L+   A     R  LAE  G     + P+S  +      + T +  P 
Sbjct: 32  SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPA 91

Query: 194 SLPPELRVKSDEPP------GPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLP 247
           S PP        PP      GP    G +     P     + L      ++ +    + P
Sbjct: 92  SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP 151

Query: 248 QLLEEEPSSMQQEAPALP--PESSME----------SLTLPNHEVSVQPPGEDQAYYHLP 295
           +       + +  +   P  P  +M            L  P      +PP E       P
Sbjct: 152 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG------P 205

Query: 296 NITVKPADVEVTITSEPT------------NETESSQAQQETPIQFPEEVEPSAT-QQEA 342
             +V  A    T    P                  S +   TP+  P    PSA     A
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265

Query: 343 PIEPPVP-PMEHELSISEQQQPVQPSESPR--EVESSPTQQETPGQ------PPEHHEVT 393
           P  P  P P   +     Q  P +   +P    + SSP    +P        PP  +  T
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT 325

Query: 394 VSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPA 453
             P     +  LA+P + + PP         PSA      +     T  S +   +  P 
Sbjct: 326 PLPATLPPSPPLATP-LPLAPPS--------PSAPPSLQTLPSPPATPPSQAPPSMTTPP 376

Query: 454 IQHGGPPLLPESSEEAGPLAVQQETSFQSPEPI-------NNENPSPTQQEAAAEHPQTA 506
           +Q   PP L        P ++   +    P P+            SPT Q   +    + 
Sbjct: 377 MQ--APPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434

Query: 507 EEGESSLTHQEAPAQTP------EFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTE 560
            + ++SLT    PA TP      + P  + A PP  + L+ A V PL    TI P     
Sbjct: 435 RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA-VSPLSSPLTIHPLQA-- 491

Query: 561 VELSPTMKETPTQPPKKVV-PQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITP 619
             LS     +P  P   ++ P L     +  P+      Q P +   T  L +L  ++ P
Sbjct: 492 --LSSLASHSPQAPLSSLIMPPLETQSSLAPPS-----LQTPPASLTTPPLENLP-SLAP 543

Query: 620 EPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTE 679
                     PP +T  +P    +T PH +               P        P  +T 
Sbjct: 544 ----------PPLQTASAP----LTTPHLETPPC-----------PAPCPLQAPPSPLTT 578

Query: 680 VEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSP 739
             P T      PPP  P     P  +G         AT  P          P   + P  
Sbjct: 579 PPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPP-------QAPPXLALPPLQ 631

Query: 740 TTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAP 775
                   PP   L+ +  P+ +  ++ A+    AP
Sbjct: 632 APPSPPASPP---LSPLATPSPQAPNALAVHLLQAP 664



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 111/481 (23%), Positives = 161/481 (33%), Gaps = 84/481 (17%)

Query: 358 SEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDV 417
           S +    +P  S R   + P +  +PG         VS PG       AS +    P   
Sbjct: 86  SSRNPASRPPASGRGERAPPAKNTSPGP--------VSSPGR------ASGTTRPGPLGQ 131

Query: 418 Q-LTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGP-PLLPESSEEAGPLAVQ 475
           + L I+AE +   G +    + +   +G+  D   P    G P P +   S  AG     
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT--PGTPSPAMARRSRAAG----- 184

Query: 476 QETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPE 535
             T    P P  +  P P  +         +   E S T     A+        + +P  
Sbjct: 185 --TEVGLPRPAPSARPRPPTE---GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 239

Query: 536 HSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQ 595
            S  + AT  PL       P ++     +P     P+QP  K +  LR  Q VT P    
Sbjct: 240 RSLSSSAT--PLSSPARSGPSARG----TPRAPAHPSQPKPKGLQALRPPQ-VTPPRKDA 292

Query: 596 DQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQH 655
             A  P+S S            TP P+       PP     +P  P    P P       
Sbjct: 293 APALGPLSSSPLA---------TPSPSGTKARPVPPPDNAATPL-PATLPPSP------- 335

Query: 656 SHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQ 715
                    PL     + P S +   PS  L T   PP  P    PPS       +  + 
Sbjct: 336 ---------PLATPLPLAPPSPS-APPS--LQTLPSPPATPPSQAPPSMTTPPMQAPPSL 383

Query: 716 ATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHS--------T 767
            T+ P+ +  ++T+ P+ +  PSP    +      LG      PT +  HS        T
Sbjct: 384 QTIPPIQVPHSLTS-PSLQAPPSPLALSSLQATTSLG-----SPTLQATHSFLTMSPRQT 437

Query: 768 ALEKTTAPRPDRV----QTLHRSLTEVTGPP--TELEPAQDSLVQSESYTQNKALTAPEE 821
               T+  RP         L   L+    PP  T L PA   L    +    +AL++   
Sbjct: 438 QASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLAS 497

Query: 822 H 822
           H
Sbjct: 498 H 498


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 78.2 bits (191), Expect = 6e-14
 Identities = 174/803 (21%), Positives = 279/803 (34%), Gaps = 117/803 (14%)

Query: 98   PPQESTENLVPFLDTWDSAGEQPL-------EPEQFLASQQDLKDKLSPQERLPVSPKKL 150
            P +  TE L+P   T D  GE+ L       E +Q LA  +D + + S +     SP++ 
Sbjct: 830  PLERETEKLLPERQT-DVTGEEELTKGKQDREQKQLLA--RDTQRQESDKNGESASPER- 885

Query: 151  KKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPS 210
                  R SL   I  + ++   Q QKQTL ++    +   P +         +  P   
Sbjct: 886  -----DRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVA-------NRECDPAEL 933

Query: 211  EQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSM 270
            E+  P    LE +TQ  E     +  S  Q+  A  P     EP     + P  P  + +
Sbjct: 934  EEKVPKVI-LERDTQRGEP----EGGSQDQKGQASSPT---PEPGVGAGDLPG-PTSAPV 984

Query: 271  ESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFP 330
             S +      S   P   Q    L N  + PA+             ++S+ +    +   
Sbjct: 985  PSGSQSGGRGSPVSPRRHQK--GLLNCKMPPAE-------------KASRIRAAEKVSRG 1029

Query: 331  EEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPT--------QQET 382
            ++  P A       E P PP +   S S++     P  SP      PT         QE 
Sbjct: 1030 DQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEA 1089

Query: 383  PGQPPEHHEVTVSPPGHHQTHHLAS----PSVSVKPPDVQLTIAAEPSAEVGTSLVHQEA 438
            P  P         P    +T   +     P+ S  P     T  A+P     TS   +  
Sbjct: 1090 PEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSR 1149

Query: 439  TTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEA 498
            T R S     V+ P              E   P A + + S  + +P+ +E   PT Q  
Sbjct: 1150 TNRSS-----VKTP--------------EPVVPTAPELQPSTSTDQPVTSE---PTSQVT 1187

Query: 499  AAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPES- 557
                 +++ +   ++       Q    P+    +P      +QAT    +     TPE  
Sbjct: 1188 RGRKSRSSVKTPETVVPTALELQ----PSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPV 1243

Query: 558  -KTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTV--QLLDLG 614
              T  EL P+   T T  P    P  +  +G  N +    +   PV P+           
Sbjct: 1244 VPTAPELQPS---TSTDQPVTSEPTYQATRGRKNRS--SVKTPEPVVPTAPELRPSTSTD 1298

Query: 615  LTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSH--------LTRATVQPL 666
              +TP+PT+    +T  +  + S K PE  +P   ++Q   S          +R T    
Sbjct: 1299 RPVTPKPTSR---TTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRT 1355

Query: 667  DLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELT 726
            ++     P+S   + P     T+   P  PE T   +   + + S  T  T+ P   +L 
Sbjct: 1356 NMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLE 1415

Query: 727  ITTKPTTEVKPSPTTEET-------STQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDR 779
             +T     V P PT++ T       S + P+  +   P    E   ST+ ++   P P  
Sbjct: 1416 PSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAP----ELQPSTSTDQPVTPEPTS 1471

Query: 780  VQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDE 839
              T  R+       P  + P    L Q+ + T     + P         N   + T    
Sbjct: 1472 QATRGRTDRSSVKTPETVVPTAPEL-QASASTDQPVTSEPTSRTTRGRKNRSSVKTPETV 1530

Query: 840  MLSCIDLNPEQRLRQVPVPEPNT 862
            + +  +L P     Q   PEP +
Sbjct: 1531 VPAAPELQPSTSTDQPVTPEPTS 1553



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 182/842 (21%), Positives = 293/842 (34%), Gaps = 127/842 (15%)

Query: 46   PLQLTSNPLGPPESWSSHSS-HFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTE 104
            P  +   P  P +  +S S  H       +P LP+            S E P  P  S  
Sbjct: 1039 PPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSS-- 1096

Query: 105  NLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEII 164
             L PF         +      F A+    +   S     PV+PK   +    R + + + 
Sbjct: 1097 ELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSV- 1155

Query: 165  GITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRV----KSDEPPGPSEQVGPSQFHL 220
                   TP+    T      ST T  P +  P  +V    KS       E V P+   L
Sbjct: 1156 ------KTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALEL 1209

Query: 221  EPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEV 280
            +P T    T   + S    Q    +  +   + P  +   AP L P +S +         
Sbjct: 1210 QPSTS---TDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTY 1266

Query: 281  SVQPPGEDQAYYHLPNITVKPA-------DVEVTITSEPTNETESSQAQQETPIQFPEEV 333
                  ++++    P   V  A         +  +T +PT+ T  S+    + ++ PE V
Sbjct: 1267 QATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSS-VKTPETV 1325

Query: 334  EPSA------TQQEAPIEPP--------------VPPMEHELSISEQQQPVQPSESPREV 373
             P+A      T  + P+ P               V   E  + I+ +  P   +E P  V
Sbjct: 1326 VPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQP--V 1383

Query: 374  ESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL 433
               PT + T G+  ++     +P     T     PS S   P     +  EP+++     
Sbjct: 1384 TPEPTSRATRGR--KNRSSGKTPETLVPTAPKLEPSTSTDQP-----VTPEPTSQ----- 1431

Query: 434  VHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEE--AGPLAVQQET-------SFQSPE 484
                AT   +   +   P  +    P L P +S +    P    Q T       S ++PE
Sbjct: 1432 ----ATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPE 1487

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
             +    P   Q  A+ + P T+E   S  T       + + P  VV   PE    T +T 
Sbjct: 1488 TVVPTAPE-LQASASTDQPVTSEP-TSRTTRGRKNRSSVKTPETVVPAAPELQPST-STD 1544

Query: 545  QPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSP 604
            QP      +TPE  +      T + +  + P+ +VP     Q    P+  ++Q   P   
Sbjct: 1545 QP------VTPEPTSRATRGRTNRSS-VKTPESIVPIAPELQ----PSTSRNQLVTPEPT 1593

Query: 605  SVTVQLLDLGLTI-TPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATV 663
            S   +      ++ TPEP         P  +   P  P++T     +   + S  T   V
Sbjct: 1594 SRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPV 1653

Query: 664  QPL--DLG-FT-----ITPKSMTEVEPSTALMTTA----PPPGHPEVTLPPSDKGQAQHS 711
            +P   DL  FT     +TP+++ +   S  L ++     P P  PE   P +        
Sbjct: 1654 EPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPE 1713

Query: 712  HLTQ--------ATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDL-----GLAIIPE 758
             +TQ        A   P  L   I  KP +     P ++ +  Q          L  IPE
Sbjct: 1714 PITQPSCIKRQRAAGNPGSLAAPIDHKPCS-APLEPKSQASRNQRWGAVRAAESLTAIPE 1772

Query: 759  PTT----ETG-HSTALEK---------TTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSL 804
            P +    ET  H++ ++K         T   +P   Q+  RSL  +  PP + +P +  +
Sbjct: 1773 PASPQLLETPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQPQRGEV 1832

Query: 805  VQ 806
             Q
Sbjct: 1833 SQ 1834



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 64/349 (18%), Positives = 130/349 (37%), Gaps = 44/349 (12%)

Query: 77   LPADPWDFDHLGPSASSEMPAPPQEST---------------ENLVPFLDTWD--SAGEQ 119
            +PA P     L PS S++ P  P+ ++               E++VP        ++  Q
Sbjct: 1531 VPAAP----ELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQ 1586

Query: 120  PLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQT 179
             + PE    + +   ++ S +   PV P   +  P           +T + +  ++ + +
Sbjct: 1587 LVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSS 1646

Query: 180  LQN----EYSSTD----TPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            ++     E +++D    TP   S+ PE   +     G S+ +  S     P    PE   
Sbjct: 1647 VKTPKPVEPAASDLEPFTPTDQSVTPEAIAQG----GQSKTLRSSTVRAMPVPTTPEFQS 1702

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTL-PNHEVSV-QPPGEDQ 289
             + +       P   P  ++ + ++    + A P +    S  L P  + S  Q  G  +
Sbjct: 1703 PVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVR 1762

Query: 290  AYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVP 349
            A     ++T  P      +   P + ++  + +     +F  E++P A+Q        + 
Sbjct: 1763 A---AESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMD 1819

Query: 350  PMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPG 398
               H      Q+QP +   S + V     +++T  +P +  +V    PG
Sbjct: 1820 SPPH------QKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPKPG 1862


>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
            sapiens]
          Length = 1393

 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 167/810 (20%), Positives = 284/810 (35%), Gaps = 113/810 (13%)

Query: 53   PLGPPESWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDT 112
            P GP E+    ++      P  PT   +    ++  PS +       + + EN  P    
Sbjct: 339  PAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAE 398

Query: 113  WDSAGEQ-PLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIG---ITR 168
                GE+ P   ++  +S  +  +     ER P++ +     PA+     E       T 
Sbjct: 399  PTEHGERTPFANDKTTSSSAESTEH---GERTPLANENTTPSPAEPTENRERTANENTTP 455

Query: 169  QLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQ---FHLEPETQ 225
              + P   ++T  NE  +T +P   +   E        P P+E     Q   F  E  T 
Sbjct: 456  SPAGPTENRETTANE-KTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTS 514

Query: 226  NP-ETLEDIQSSSLQQE----APAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEV 280
            +  E  E  + + L  E    +PA+  +  E   +     +PA P E+  +   L N + 
Sbjct: 515  SSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENG-DRTPLANEKT 573

Query: 281  --SVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQE----TPIQFPEEVE 334
              S+  P E+       N      +   + ++EPT   E +    E    +P +  E  E
Sbjct: 574  TPSLAEPTENGQRTPFAN------EKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRE 627

Query: 335  PSATQQEAPIEPPVPPMEHELSISEQQQ--PVQPSESPREVESSPTQQETPGQPPEHHEV 392
             +A +   P  P  P    E++ +E+    P +P+E+ RE  ++     +P +P E+ + 
Sbjct: 628  RTANENTTP-SPAGPTENREMTANEKTTLFPAEPTEN-RERTANEKTTSSPAEPTENGQR 685

Query: 393  T-----------VSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTR 441
            T             P  H +   LA+ + ++ P +   T   E +A   T+    E T  
Sbjct: 686  TPFANEKTTSSSAEPTEHGERTPLANENTTLSPAEP--TENRERTANEKTTPFPAEPTEN 743

Query: 442  LSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAE 501
               + N+   P+      P  P  + +  PLA  ++T+    EP  N   +P   E    
Sbjct: 744  RERTANENTTPS------PAQPTENGDRTPLA-NEKTTPSLAEPTENGKRTPFANEKTTS 796

Query: 502  HPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEV 561
                     SS    E   +TP       + P E +   + T       F   P    E 
Sbjct: 797  ---------SSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRES 847

Query: 562  ELSPTMKETPTQPPKKVVPQLRVYQGVTNPT--PGQDQAQHPVSPSVTVQLLDLGLTITP 619
              +      P +P +      R +    N T  P +      ++P     L +   T++P
Sbjct: 848  TANEKTTPFPAEPTEN-----REWTANENTTLSPAEPTEHEEMTP-----LANEKTTLSP 897

Query: 620  EPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTE 679
               TE G  TP      +P   E T  H ++    +   T +  +P + G  I  +  T 
Sbjct: 898  AEPTENGERTPFTNEKTTPSSAEPT-EHGERTPLANEITTPSRAEPTEHGERIANEKATP 956

Query: 680  VEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSP 739
                    + A P  H E T+         +   T ++ +P           T   + +P
Sbjct: 957  --------SPAKPTEHGETTV---------NEDTTPSSAEP-----------TENGERTP 988

Query: 740  TTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHR--SLTEVTGPPTEL 797
               E +T  P          +TE G  TA EKTT    +  +   R  S  E T P    
Sbjct: 989  LANENTTTSPT--------ESTEHGERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAK 1040

Query: 798  EPAQDSLVQSESYTQNKALTAPEEHKASTS 827
                + +  S +     +   P EH   T+
Sbjct: 1041 PTEHEEMTPSANENTTPSPVKPTEHGEKTT 1070



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 147/737 (19%), Positives = 232/737 (31%), Gaps = 115/737 (15%)

Query: 168 RQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227
           R L    S           T T +  S   + + KS   P        + +      +  
Sbjct: 187 RPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEES 246

Query: 228 ETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGE 287
           E  ED +++    +   +  + ++E  S+ +       P          N+  S   P E
Sbjct: 247 EKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTE 306

Query: 288 DQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPP 347
           ++      N T+ PA        EP    E +  +   P           T  E     P
Sbjct: 307 NRERTANENTTLSPA--------EPIENRERTANENTAPFPAGPTENREMTANENTTLFP 358

Query: 348 VPPMEHELSISEQQQPVQPSESPREVESSPTQQET--PGQPPEH---------------- 389
             P EH    + +     P+E     E +  +  T  P +P EH                
Sbjct: 359 AEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSA 418

Query: 390 ------------HEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQE 437
                       +E T   P     +   + + +  P     T   E +A   T+L   E
Sbjct: 419 ESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVE 478

Query: 438 ATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP-------EPINNEN 490
            T     + N+   P+      P  P  + +  P A ++ TS  +         P+ NEN
Sbjct: 479 PTENRETTANEKTTPS------PAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANEN 532

Query: 491 PSPTQQEAAAEHPQTAEE--GESSLTHQEAPAQTP---EFPNVVVAQPPEHSHLTQATVQ 545
            +P+  E      +TA E    S     E   +TP   E     +A+P E+   T    +
Sbjct: 533 TTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANE 592

Query: 546 PLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPS 605
                 T +    TE E    +    T P      + R      N TP       P  P+
Sbjct: 593 KT----TSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPS------PAGPT 642

Query: 606 VTVQL-LDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQ 664
              ++  +   T+ P   TE    T  ++T  SP  P     +  +    +   T ++ +
Sbjct: 643 ENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEP---TENGQRTPFANEKTTSSSAE 699

Query: 665 PLDLG---------FTITPKSMTEVEPSTALMTTAPPPGHP---------EVTLP----P 702
           P + G          T++P   TE    TA   T P P  P         E T P    P
Sbjct: 700 PTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQP 759

Query: 703 SDKGQ---AQHSHLTQATVQPLD--LELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIP 757
           ++ G      +   T +  +P +         + TT     PT     T   +      P
Sbjct: 760 TENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSP 819

Query: 758 EPTTETGHSTALEKTT----APRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQN 813
              TE    TA EKTT     P  +R  T +   T     PTE          +  +T N
Sbjct: 820 AEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTE----------NREWTAN 869

Query: 814 KALT----APEEHKAST 826
           +  T     P EH+  T
Sbjct: 870 ENTTLSPAEPTEHEEMT 886



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 106/502 (21%), Positives = 178/502 (35%), Gaps = 78/502 (15%)

Query: 50   TSNPLGPPESWSSHSSHFPRESPHAPTLPADPWDF-DHLGPSASSEMPAPPQESTENLVP 108
            TS+   P E    H+   P  + +  + PA+P +  +      +++ PA P E+ E+   
Sbjct: 795  TSSSAEPTE----HAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTAN 850

Query: 109  FLDTWDSAGEQPLEPEQFLASQQDLKDKLSP---QERLPVSPKKLKKDPAQRWSLAEIIG 165
               T   A  +P E  ++ A++        P   +E  P++ +K    PA+     E   
Sbjct: 851  EKTTPFPA--EPTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTP 908

Query: 166  ITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPE-- 223
             T + +TP S + T   E     TP    +    R    EP    E++   +    P   
Sbjct: 909  FTNEKTTPSSAEPTEHGER----TPLANEITTPSRA---EPTEHGERIANEKATPSPAKP 961

Query: 224  TQNPETL--EDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVS 281
            T++ ET   ED   SS +     +   L  E  ++        P ES+       N + +
Sbjct: 962  TEHGETTVNEDTTPSSAEPTENGERTPLANENTTTS-------PTESTEHGERTANEKTT 1014

Query: 282  VQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQE----TPIQFPEEVEPSA 337
              P    +     P+   K     +   ++PT   E + +  E    +P++  E  E + 
Sbjct: 1015 PSPAEPTEHGERTPSANEKT----IPSPAKPTEHEEMTPSANENTTPSPVKPTEHGEKTT 1070

Query: 338  TQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSP- 396
               E     P  P EH    +   + + PS +               +P EH E T SP 
Sbjct: 1071 LANEKITLSPEGPTEHGAKTTSANEKITPSLA---------------KPTEHGERTTSPN 1115

Query: 397  ------PGHHQTHHLASPSVSVKPP--------DVQLTIAAEPSAEV-GTSLVHQEATTR 441
                        H   + S +V  P          + T+A E   +V   S  H E TT 
Sbjct: 1116 DKITSSAAESTEHRDRATSANVITPAPAEPIKHAKRTTLAHEKMTQVTEKSTEHPEKTTS 1175

Query: 442  LS-GSGNDVEPPAI--------QHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPS 492
             +  +    E P +        +    P+  + +E  G   +  ET  ++P   + ENP 
Sbjct: 1176 TTEKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTET-IKAPVK-STENPE 1233

Query: 493  PTQQEAAAEHPQTAEEGESSLT 514
             T        P     G+ SLT
Sbjct: 1234 KTAAVTKTIKPSVKVTGDKSLT 1255



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 70/333 (21%), Positives = 118/333 (35%), Gaps = 51/333 (15%)

Query: 475 QQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPP 534
           +  T      P + EN S   ++    + ++ +  +S+ TH+E+  +             
Sbjct: 109 KSSTDNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGK------------- 155

Query: 535 EHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPG 594
              H+T A            P+SK     S T K T T+   K    L       + T  
Sbjct: 156 --KHITPA------------PKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTST 201

Query: 595 QDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQ 654
                   S   T    + G + T + +T    S P K T  S    + T    +  +T+
Sbjct: 202 S-------SHKTTTSFHNSGNSQTKQKST----SFPEKITAASKTTYKTTGTPEESEKTE 250

Query: 655 HSHLTRATVQPL-----DLGFTITPKSMTE--VEPSTALMTTAPPPGHPEVTLPPSDKGQ 707
            S  T A+ + L     ++  TI+   +T+   EP+     TA     P    P  ++ +
Sbjct: 251 DSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRER 310

Query: 708 AQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHST 767
             + + T +  +P++       + T      PT  E      +    + P   TE G  T
Sbjct: 311 TANENTTLSPAEPIENRERTANENTAPFPAGPT--ENREMTANENTTLFPAEPTEHGERT 368

Query: 768 ALEKTTAPRPDRVQTLHRSLTEVTGP----PTE 796
           A E TT    +  +   R+  E T P    PTE
Sbjct: 369 ANENTTPSPAEPTEHGERTANENTTPSPAEPTE 401



 Score = 33.1 bits (74), Expect = 2.4
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 31/146 (21%)

Query: 1200 AAEEKRLTSPA-PREVEQ------PHTQQGPEK---------LAGNAVYTKPSFTQEH-- 1241
            +A EK + SPA P E E+       +T   P K         LA   +   P    EH  
Sbjct: 1029 SANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEHGEKTTLANEKITLSPEGPTEHGA 1088

Query: 1242 -------KAAVSVLKPFSKGAPSTSSPAKALPQVRDRSKDLTHAISILESAKARVTNTKT 1294
                   K   S+ KP   G  +TS   K      + ++    A S      A V     
Sbjct: 1089 KTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAESTEHRDRATS------ANVITPAP 1142

Query: 1295 SKPIVHARKKYRFHKTRSHVTHRTTK 1320
            ++PI HA++    H+  + VT ++T+
Sbjct: 1143 AEPIKHAKRTTLAHEKMTQVTEKSTE 1168


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 151/673 (22%), Positives = 231/673 (34%), Gaps = 107/673 (15%)

Query: 170 LSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPP-GPSEQVGPSQFHLEPETQNPE 228
           LS  + Q+   Q  +   D P PG +P EL    + PP  P   + PSQ ++ P      
Sbjct: 115 LSYQKQQQYKHQMLHHQRDGP-PGLVPMELESPPESPPVPPGSYMPPSQSYMPPP----- 168

Query: 229 TLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGED 288
                      Q  P+  P      P+S Q   P LPP     S + P+       P   
Sbjct: 169 -----------QPPPSYYP------PTSSQ---PYLPPAQPSPSQSPPSQSYLAPTPSYS 208

Query: 289 QAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV 348
            +           +    +  S   +   SSQA    P Q       S +Q  AP  P  
Sbjct: 209 SS-----------SSSSQSYLSHSQSYLPSSQASPSRPSQ-----GHSKSQLLAPPPPSA 252

Query: 349 PPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ---THHL 405
           PP       + QQ+P+   ES  + +S+  QQ  P   P     T++P    Q     HL
Sbjct: 253 PPGN---KTTVQQEPL---ESGAKNKSTEQQQAAPEPDPS----TMTPQEQQQYWYRQHL 302

Query: 406 ASPSVSVK---PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLL 462
            S     K   P   +  + A+ + E     V   AT+++  S +  EPP         L
Sbjct: 303 LSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPP---------L 353

Query: 463 PESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQT 522
           P  +EE  P    +E   + PE    E+    Q +AAA H Q  ++      +Q    + 
Sbjct: 354 PPPNEEVPPPLPPEEPQSEDPE----EDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKH 409

Query: 523 PEFPNVV-----VAQPPEHSHLTQATVQPLDLGFTITP----ESKTEVELSPTMKETPTQ 573
            +   ++     + QPP H       +Q                + E E     ++  + 
Sbjct: 410 TQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSY 469

Query: 574 PPKKVVP----QLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHST 629
           P K  +     Q + +QG    T  Q   Q  V+    ++   +G    P P        
Sbjct: 470 PHKDQLQEYEKQWKTWQGHMKAT--QSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMP 527

Query: 630 PPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTT 689
           PP  T+  P  P  +LP P              V P  L  T+ P  M       +L T+
Sbjct: 528 PPLPTMPPPVLPP-SLPPP--------------VMPPALPATVPPPGMPPPVMPPSLPTS 572

Query: 690 APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSP----TTEETS 745
            PPPG P                L+ A   P+    ++++     V P P     T    
Sbjct: 573 VPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPG 632

Query: 746 TQPPDLGLAIIPEPT-TETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSL 804
             PP +   I P+ T      +++ + +  P   R   L   ++  + PPT   P   S 
Sbjct: 633 IPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSA 692

Query: 805 VQSESYTQNKALT 817
             SE       L+
Sbjct: 693 GPSEQVNSKAPLS 705



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 124/590 (21%), Positives = 198/590 (33%), Gaps = 91/590 (15%)

Query: 46  PLQLTSNPLGPPESWSSH----SSHFPRESP---HAPTLPADPWDFDHLGPSASSEMPAP 98
           P++L S P  PP    S+     S+ P   P   + P   + P+    L P+  S   +P
Sbjct: 140 PMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPY----LPPAQPSPSQSP 195

Query: 99  PQESTENLVPFLDTWDSAGEQPLEPEQ-FLASQQDLKDKLSPQERLPVSPKKLKKDPAQR 157
           P +S     P   +  S+ +  L   Q +L S Q              SP +    P+Q 
Sbjct: 196 PSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQ-------------ASPSR----PSQG 238

Query: 158 WSLAEIIGITRQLSTPQSQKQTLQNE-------------YSSTDTPYPGSLPPELRVKSD 204
            S ++++      S P   K T+Q E               +   P P ++ P+ + +  
Sbjct: 239 HSKSQLLAPPPP-SAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYW 297

Query: 205 EPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPAL 264
                      ++ HL    + P   +D     +++E        + E PSS   E P L
Sbjct: 298 YRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEP-VKEEVTVPATSQVPESPSS---EEPPL 353

Query: 265 PPESSMESLTLPNHEVSVQPPGED-------QAYYHLPNITVKPADVEVTITSEPTNETE 317
           PP +      LP  E   + P ED        A  H           +     +   + +
Sbjct: 354 PPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQ 413

Query: 318 SSQAQQETPIQFPEEVEPSAT--------QQEAPIEPPVPPMEHELSISEQQQPVQP-SE 368
               Q +  IQ P  ++  +          Q+   +      E E  + E+Q    P  +
Sbjct: 414 QILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKD 473

Query: 369 SPREVESS-PTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA 427
             +E E    T Q        + +  V+   + +  ++   ++S+ PP V  +    P  
Sbjct: 474 QLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMG--NMSMPPPFVPYSQMPPPLP 531

Query: 428 EVGTSLVHQE-----------ATTRLSGSGNDVEPPAIQHG-GPPLLPESSEEAGPLAVQ 475
            +   ++              AT    G    V PP++     PP +P S   AGP  V 
Sbjct: 532 TMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVL 591

Query: 476 QETSFQS--PEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQP 533
              S  S  P P+      P    + A  P       SS T    P   P  P V    P
Sbjct: 592 PPPSLSSAGPPPV----LPPPSLSSTAPPPVMPLPPLSSAT--PPPGIPP--PGVPQGIP 643

Query: 534 PEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLR 583
           P+   LT A V P     +     K    L PT     + PP    P L+
Sbjct: 644 PQ---LTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQ 690


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 147/613 (23%), Positives = 202/613 (32%), Gaps = 101/613 (16%)

Query: 90  SASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKD---KLSPQERLPVS 146
           S   + PA P   T    P  +   S+G     P     S  D K    K S ++    +
Sbjct: 32  SGRKKQPASPDGRTS---PINEDIRSSGRN--SPSAASTSSNDSKAETVKKSAKKVKEEA 86

Query: 147 PKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGS-LPPELRVKSDE 205
              LK +  QR    E +    + +   S K+T   E S  ++P  G     + R  +DE
Sbjct: 87  SSPLKSNKRQR----EKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE 142

Query: 206 PPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALP 265
                + +        P   +P+  E    SS QQ       Q+L+ +P ++Q      P
Sbjct: 143 GSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQ-------QMLQAQPPALQAPTGVTP 195

Query: 266 PESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQET 325
             SS              PPG  Q    LP     P+   V     PT    +SQA  + 
Sbjct: 196 APSSA-------------PPGTPQ----LPTPGPTPSATAVPPQGSPT----ASQAPNQP 234

Query: 326 PIQFPEEVEPSATQQEAP-IEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPG 384
             Q P    P    Q+AP + P  PP  H         P+QP        S+P+      
Sbjct: 235 --QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSH----A 288

Query: 385 QPPEHHEVTVSPPGHHQ------THHLASPSVSVKPPDVQLTIAAEPSAEVGTS--LVHQ 436
           QPP H +    PPG H         H   P     PP      A++  A +GTS    + 
Sbjct: 289 QPPLHGQ---GPPGPHSLQAGPLLQHPGPPQPFGLPPQ-----ASQGQAPLGTSPAAAYP 340

Query: 437 EATTRLSGSGNDVE-------------PPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP 483
             + +L  S + ++             P A+ H  PP      +   P A +       P
Sbjct: 341 HTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGP 400

Query: 484 EPIN---NENPSPTQQ---EAAAEHPQTAEEGESSLTHQ-----EAPAQTPEFPNVVVAQ 532
            P +   N  P P  +     +  HP +A      L  Q      +PAQ P         
Sbjct: 401 SPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLP 460

Query: 533 PPEHSH----LTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGV 588
           PP  SH    L Q   QP        P     +   PT   T T P            G 
Sbjct: 461 PPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI-TPPTCPSTSTPPAGPGTSAQPPCSGA 519

Query: 589 TNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLP-H 647
                G   A     P  TVQ+ +  L    EP      S PP     SP+   V  P H
Sbjct: 520 A--ASGGSIAGGSSCPLPTVQIKEEALDDAEEP-----ESPPPPPRSPSPEPTVVDTPSH 572

Query: 648 PDQVQTQHSHLTR 660
             Q    + HL R
Sbjct: 573 ASQSARFYKHLDR 585



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 133/624 (21%), Positives = 202/624 (32%), Gaps = 113/624 (18%)

Query: 180 LQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQ 239
           L  ++S       GS+      +  +P  P  +  P    +    +N  +     S+  +
Sbjct: 12  LSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSK 71

Query: 240 QEAPAQLPQLLEEEPSS------MQQEAPALPPESS---------MESLTLPNH------ 278
            E   +  + ++EE SS       Q+E  A   E +          + ++ PN       
Sbjct: 72  AETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEG 131

Query: 279 EVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQF--PEEVEPS 336
           E S      D+      +I         +I S   NE++S  + Q+  +Q   P    P+
Sbjct: 132 ESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT 191

Query: 337 ATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSP 396
                    PP  P       +     V P  SP     +P Q + P  P  H  +  +P
Sbjct: 192 GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPT-ASQAPNQPQAPTAPVPHTHIQQAP 250

Query: 397 PGHHQ---THHLASPSVSVKPPDVQLT-IAAEPSAEVGTSLVHQEATTRLSGSGND---- 448
             H Q   + H   P  S  PP   LT  A +PSA          A   L G G      
Sbjct: 251 ALHPQRPPSPH-PPPHPSPHPPLQPLTGSAGQPSAP-------SHAQPPLHGQGPPGPHS 302

Query: 449 -VEPPAIQHGGPP----LLPESSEEAGPL-----AVQQETSFQSPEPINNENPSPTQQEA 498
               P +QH GPP    L P++S+   PL     A    TS Q P        +   Q+ 
Sbjct: 303 LQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA----SQSALQSQQP 358

Query: 499 AAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHS-HLTQATVQPLDLGFTITPES 557
             E P        ++ H + P  TP  P +   Q  +H  HL+  +   ++      P  
Sbjct: 359 PREQP--LPPAPLAMPHIKPPPTTP-IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPAL 415

Query: 558 KTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTI 617
           K    LS     +   PP +++PQ +         PG  Q+Q+                +
Sbjct: 416 KPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN----------------L 459

Query: 618 TPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSM 677
            P P      S PP                        + L +   QP        P   
Sbjct: 460 PPPPA-----SHPP------------------------TGLHQVAPQPPFAQHPFVPGGP 490

Query: 678 TEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKP 737
             + P T   T+ PP G      PP     A    +   +  PL         PT ++K 
Sbjct: 491 PPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPL---------PTVQIKE 541

Query: 738 SPTTE-ETSTQPPDLGLAIIPEPT 760
               + E    PP    +  PEPT
Sbjct: 542 EALDDAEEPESPPPPPRSPSPEPT 565



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 107/499 (21%), Positives = 158/499 (31%), Gaps = 82/499 (16%)

Query: 79  ADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLS 138
           +DP D D    S S  +P+P    +++        DS+ +Q +   Q  A Q       +
Sbjct: 145 SDPKDIDQDNRSTSPSIPSPQDNESDS--------DSSAQQQMLQAQPPALQAPTGVTPA 196

Query: 139 PQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE 198
           P    P +P+     P    +     G       P +Q Q        T      +L P+
Sbjct: 197 PSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAP-NQPQAPTAPVPHTHIQQAPALHPQ 255

Query: 199 LRVKSDEPPGPS-------------EQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQ 245
                  PP PS             +   PS        Q P     +Q+  L Q     
Sbjct: 256 RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP- 314

Query: 246 LPQLLEEEPSSMQQEAP------ALPPESSMESLTLPNHEVSVQPPGED---QAYYHLPN 296
            PQ     P + Q +AP      A  P +S++     +   S QPP E     A   +P+
Sbjct: 315 -PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH 373

Query: 297 ITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELS 356
           I   P        + P  +  + QA +      P    PS     A + P  PP    LS
Sbjct: 374 IKPPP--------TTPIPQLPAPQAHKHP----PHLSGPSPFSMNANLPP--PPALKPLS 419

Query: 357 ISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPD 416
                 P  PS  P  ++  P  Q  P  P +       PPG  Q+ +L  P  S  P  
Sbjct: 420 SLSTHHP--PSAHPPPLQLMPQSQPLPSSPAQ-------PPGLTQSQNLPPPPASHPPTG 470

Query: 417 VQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQ 476
           +       P A                      + P +  G PP+ P +           
Sbjct: 471 LHQVAPQPPFA----------------------QHPFVPGGPPPITPPTCPSTSTPPAGP 508

Query: 477 ETSFQSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPN--VVVAQ 532
            TS Q P      +       ++   P  Q  EE        E+P   P  P+    V  
Sbjct: 509 GTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVD 568

Query: 533 PPEHSHLTQATVQPLDLGF 551
            P H+  +    + LD G+
Sbjct: 569 TPSHASQSARFYKHLDRGY 587



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 96/499 (19%), Positives = 153/499 (30%), Gaps = 73/499 (14%)

Query: 308 ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAP--IEPPVPPMEHELSISEQQQPV- 364
           +  E ++  +S++ Q+E      EE + +++++     I  P  P E E   S+ +    
Sbjct: 82  VKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVND 141

Query: 365 QPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAE 424
           + S  P++++            P+ +E         Q        +  +PP +Q      
Sbjct: 142 EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM-------LQAQPPALQAPTGVT 194

Query: 425 PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE 484
           P+         Q  T   + S   V P     G P      ++   P A    T  Q   
Sbjct: 195 PAPSSAPPGTPQLPTPGPTPSATAVPP----QGSPTASQAPNQPQAPTAPVPHTHIQQAP 250

Query: 485 PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
            ++ + P        + HP         L      A  P  P+   AQPP H        
Sbjct: 251 ALHPQRPP-------SPHPPPHPSPHPPLQPLTGSAGQPSAPSH--AQPPLHGQ------ 295

Query: 545 QPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPG----QDQAQH 600
                     P     ++  P ++      P  + PQ    Q     +P         Q 
Sbjct: 296 ---------GPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQL 346

Query: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
           P S S             P     + H  PP      P  P   LP P Q      HL+ 
Sbjct: 347 PASQSALQSQQPPREQPLPPAPLAMPHIKPP------PTTPIPQLPAP-QAHKHPPHLSG 399

Query: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            +  P  +   + P     ++P ++L T  PP  H     PP  +   Q   L  +  QP
Sbjct: 400 PS--PFSMNANLPPPPA--LKPLSSLSTHHPPSAH-----PPPLQLMPQSQPLPSSPAQP 450

Query: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
             L  +    P     P     + + QPP      +P                 P P   
Sbjct: 451 PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP---------------GGPPPITP 495

Query: 781 QTLHRSLTEVTGPPTELEP 799
            T   + T   GP T  +P
Sbjct: 496 PTCPSTSTPPAGPGTSAQP 514



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 87/351 (24%), Positives = 119/351 (33%), Gaps = 64/351 (18%)

Query: 46  PLQLTSNPLGPPESWSSHSSHFPRESPHAP-TLPADPWDFDHLGPSASSEMPAPPQESTE 104
           PLQ  +   G P + S        + P  P +L A P    H GP     +P  PQ S +
Sbjct: 271 PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL-LQHPGPPQPFGLP--PQAS-Q 326

Query: 105 NLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEII 164
              P L T   A   P    Q  ASQ  L+ +  P+E+ P+ P  L     +      I 
Sbjct: 327 GQAP-LGT-SPAAAYPHTSLQLPASQSALQSQQPPREQ-PLPPAPLAMPHIKPPPTTPI- 382

Query: 165 GITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPET 224
               QL  PQ+ K                  PP L              GPS F +    
Sbjct: 383 ---PQLPAPQAHKH-----------------PPHLS-------------GPSPFSMNANL 409

Query: 225 QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPN------- 277
             P  L+ + S S      A  P L     S     +PA PP    +S  LP        
Sbjct: 410 PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP-GLTQSQNLPPPPASHPP 468

Query: 278 ---HEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFP-EEV 333
              H+V+ QPP     +   P +   P      IT      T +  A   T  Q P    
Sbjct: 469 TGLHQVAPQPP-----FAQHPFVPGGPP----PITPPTCPSTSTPPAGPGTSAQPPCSGA 519

Query: 334 EPSATQQEAPIEPPVPPME-HELSISEQQQPVQPSESPREVESSPTQQETP 383
             S          P+P ++  E ++ + ++P  P   PR     PT  +TP
Sbjct: 520 AASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 570


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 147/613 (23%), Positives = 202/613 (32%), Gaps = 101/613 (16%)

Query: 90   SASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKD---KLSPQERLPVS 146
            S   + PA P   T    P  +   S+G     P     S  D K    K S ++    +
Sbjct: 586  SGRKKQPASPDGRTS---PINEDIRSSGRN--SPSAASTSSNDSKAETVKKSAKKVKEEA 640

Query: 147  PKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGS-LPPELRVKSDE 205
               LK +  QR    E +    + +   S K+T   E S  ++P  G     + R  +DE
Sbjct: 641  SSPLKSNKRQR----EKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE 696

Query: 206  PPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALP 265
                 + +        P   +P+  E    SS QQ       Q+L+ +P ++Q      P
Sbjct: 697  GSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQ-------QMLQAQPPALQAPTGVTP 749

Query: 266  PESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQET 325
              SS              PPG  Q    LP     P+   V     PT    +SQA  + 
Sbjct: 750  APSSA-------------PPGTPQ----LPTPGPTPSATAVPPQGSPT----ASQAPNQP 788

Query: 326  PIQFPEEVEPSATQQEAP-IEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPG 384
              Q P    P    Q+AP + P  PP  H         P+QP        S+P+      
Sbjct: 789  --QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSH----A 842

Query: 385  QPPEHHEVTVSPPGHHQ------THHLASPSVSVKPPDVQLTIAAEPSAEVGTS--LVHQ 436
            QPP H +    PPG H         H   P     PP      A++  A +GTS    + 
Sbjct: 843  QPPLHGQ---GPPGPHSLQAGPLLQHPGPPQPFGLPPQ-----ASQGQAPLGTSPAAAYP 894

Query: 437  EATTRLSGSGNDVE-------------PPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP 483
              + +L  S + ++             P A+ H  PP      +   P A +       P
Sbjct: 895  HTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGP 954

Query: 484  EPIN---NENPSPTQQ---EAAAEHPQTAEEGESSLTHQ-----EAPAQTPEFPNVVVAQ 532
             P +   N  P P  +     +  HP +A      L  Q      +PAQ P         
Sbjct: 955  SPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLP 1014

Query: 533  PPEHSH----LTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGV 588
            PP  SH    L Q   QP        P     +   PT   T T P            G 
Sbjct: 1015 PPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI-TPPTCPSTSTPPAGPGTSAQPPCSGA 1073

Query: 589  TNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLP-H 647
                 G   A     P  TVQ+ +  L    EP      S PP     SP+   V  P H
Sbjct: 1074 A--ASGGSIAGGSSCPLPTVQIKEEALDDAEEP-----ESPPPPPRSPSPEPTVVDTPSH 1126

Query: 648  PDQVQTQHSHLTR 660
              Q    + HL R
Sbjct: 1127 ASQSARFYKHLDR 1139



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 145/670 (21%), Positives = 223/670 (33%), Gaps = 123/670 (18%)

Query: 118  EQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEI-IGITRQLSTPQSQ 176
            E+P++P  F+        K   +E   +S K   +    R S++ +  G  +Q ++P  +
Sbjct: 546  EKPVDPPPFMF-------KPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGR 598

Query: 177  KQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSS 236
               +  +  S+    P +        +      +E V  S   ++ E  +P     ++S+
Sbjct: 599  TSPINEDIRSSGRNSPSA------ASTSSNDSKAETVKKSAKKVKEEASSP-----LKSN 647

Query: 237  SLQQEAPA----QLPQLLEEEPSSMQQEAPALPPESSMESLTLP--NHEVSVQPPGEDQA 290
              Q+E  A    +  +   ++  + +   P  P E   ES      N E S  P   DQ 
Sbjct: 648  KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQD 707

Query: 291  YYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPP 350
                      P D E        ++++SS  QQ    Q P    P+         PP  P
Sbjct: 708  NRSTSPSIPSPQDNE--------SDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP 759

Query: 351  MEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ---THHLAS 407
                   +     V P  SP     +P Q + P  P  H  +  +P  H Q   + H   
Sbjct: 760  QLPTPGPTPSATAVPPQGSPT-ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH-PP 817

Query: 408  PSVSVKPPDVQLT-IAAEPSAEVGTSLVHQEATTRLSGSGND-----VEPPAIQHGGPP- 460
            P  S  PP   LT  A +PSA          A   L G G          P +QH GPP 
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAP-------SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870

Query: 461  ---LLPESSEEAGPL-----AVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESS 512
               L P++S+   PL     A    TS Q P        +   Q+   E P        +
Sbjct: 871  PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA----SQSALQSQQPPREQP--LPPAPLA 924

Query: 513  LTHQEAPAQTPEFPNVVVAQPPEHS-HLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
            + H + P  TP  P +   Q  +H  HL+  +   ++      P  K    LS     + 
Sbjct: 925  MPHIKPPPTTP-IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA 983

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
              PP +++PQ +         PG  Q+Q+                + P P      S PP
Sbjct: 984  HPPPLQLMPQSQPLPSSPAQPPGLTQSQN----------------LPPPPA-----SHPP 1022

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
                                    + L +   QP        P     + P T   T+ P
Sbjct: 1023 ------------------------TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 1058

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTE-ETSTQPPD 750
            P G      PP     A    +   +  PL         PT ++K     + E    PP 
Sbjct: 1059 PAGPGTSAQPPCSGAAASGGSIAGGSSCPL---------PTVQIKEEALDDAEEPESPPP 1109

Query: 751  LGLAIIPEPT 760
               +  PEPT
Sbjct: 1110 PPRSPSPEPT 1119



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 107/499 (21%), Positives = 158/499 (31%), Gaps = 82/499 (16%)

Query: 79   ADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLS 138
            +DP D D    S S  +P+P    +++        DS+ +Q +   Q  A Q       +
Sbjct: 699  SDPKDIDQDNRSTSPSIPSPQDNESDS--------DSSAQQQMLQAQPPALQAPTGVTPA 750

Query: 139  PQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE 198
            P    P +P+     P    +     G       P +Q Q        T      +L P+
Sbjct: 751  PSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAP-NQPQAPTAPVPHTHIQQAPALHPQ 809

Query: 199  LRVKSDEPPGPS-------------EQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQ 245
                   PP PS             +   PS        Q P     +Q+  L Q     
Sbjct: 810  RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP- 868

Query: 246  LPQLLEEEPSSMQQEAP------ALPPESSMESLTLPNHEVSVQPPGED---QAYYHLPN 296
             PQ     P + Q +AP      A  P +S++     +   S QPP E     A   +P+
Sbjct: 869  -PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH 927

Query: 297  ITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELS 356
            I   P        + P  +  + QA +      P    PS     A + P  PP    LS
Sbjct: 928  IKPPP--------TTPIPQLPAPQAHKHP----PHLSGPSPFSMNANLPP--PPALKPLS 973

Query: 357  ISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPD 416
                  P  PS  P  ++  P  Q  P  P +       PPG  Q+ +L  P  S  P  
Sbjct: 974  SLSTHHP--PSAHPPPLQLMPQSQPLPSSPAQ-------PPGLTQSQNLPPPPASHPPTG 1024

Query: 417  VQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQ 476
            +       P A                      + P +  G PP+ P +           
Sbjct: 1025 LHQVAPQPPFA----------------------QHPFVPGGPPPITPPTCPSTSTPPAGP 1062

Query: 477  ETSFQSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPN--VVVAQ 532
             TS Q P      +       ++   P  Q  EE        E+P   P  P+    V  
Sbjct: 1063 GTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVD 1122

Query: 533  PPEHSHLTQATVQPLDLGF 551
             P H+  +    + LD G+
Sbjct: 1123 TPSHASQSARFYKHLDRGY 1141



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 96/499 (19%), Positives = 153/499 (30%), Gaps = 73/499 (14%)

Query: 308  ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAP--IEPPVPPMEHELSISEQQQPV- 364
            +  E ++  +S++ Q+E      EE + +++++     I  P  P E E   S+ +    
Sbjct: 636  VKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVND 695

Query: 365  QPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAE 424
            + S  P++++            P+ +E         Q        +  +PP +Q      
Sbjct: 696  EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM-------LQAQPPALQAPTGVT 748

Query: 425  PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE 484
            P+         Q  T   + S   V P     G P      ++   P A    T  Q   
Sbjct: 749  PAPSSAPPGTPQLPTPGPTPSATAVPP----QGSPTASQAPNQPQAPTAPVPHTHIQQAP 804

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
             ++ + P        + HP         L      A  P  P+   AQPP H        
Sbjct: 805  ALHPQRPP-------SPHPPPHPSPHPPLQPLTGSAGQPSAPSH--AQPPLHGQ------ 849

Query: 545  QPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPG----QDQAQH 600
                      P     ++  P ++      P  + PQ    Q     +P         Q 
Sbjct: 850  ---------GPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQL 900

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            P S S             P     + H  PP      P  P   LP P Q      HL+ 
Sbjct: 901  PASQSALQSQQPPREQPLPPAPLAMPHIKPP------PTTPIPQLPAP-QAHKHPPHLSG 953

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
             +  P  +   + P     ++P ++L T  PP  H     PP  +   Q   L  +  QP
Sbjct: 954  PS--PFSMNANLPPPPA--LKPLSSLSTHHPPSAH-----PPPLQLMPQSQPLPSSPAQP 1004

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
              L  +    P     P     + + QPP      +P                 P P   
Sbjct: 1005 PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP---------------GGPPPITP 1049

Query: 781  QTLHRSLTEVTGPPTELEP 799
             T   + T   GP T  +P
Sbjct: 1050 PTCPSTSTPPAGPGTSAQP 1068



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 87/351 (24%), Positives = 119/351 (33%), Gaps = 64/351 (18%)

Query: 46   PLQLTSNPLGPPESWSSHSSHFPRESPHAP-TLPADPWDFDHLGPSASSEMPAPPQESTE 104
            PLQ  +   G P + S        + P  P +L A P    H GP     +P  PQ S +
Sbjct: 825  PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL-LQHPGPPQPFGLP--PQAS-Q 880

Query: 105  NLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEII 164
               P L T   A   P    Q  ASQ  L+ +  P+E+ P+ P  L     +      I 
Sbjct: 881  GQAP-LGT-SPAAAYPHTSLQLPASQSALQSQQPPREQ-PLPPAPLAMPHIKPPPTTPI- 936

Query: 165  GITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPET 224
                QL  PQ+ K                  PP L              GPS F +    
Sbjct: 937  ---PQLPAPQAHKH-----------------PPHLS-------------GPSPFSMNANL 963

Query: 225  QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPN------- 277
              P  L+ + S S      A  P L     S     +PA PP    +S  LP        
Sbjct: 964  PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP-GLTQSQNLPPPPASHPP 1022

Query: 278  ---HEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFP-EEV 333
               H+V+ QPP     +   P +   P      IT      T +  A   T  Q P    
Sbjct: 1023 TGLHQVAPQPP-----FAQHPFVPGGPP----PITPPTCPSTSTPPAGPGTSAQPPCSGA 1073

Query: 334  EPSATQQEAPIEPPVPPME-HELSISEQQQPVQPSESPREVESSPTQQETP 383
              S          P+P ++  E ++ + ++P  P   PR     PT  +TP
Sbjct: 1074 AASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 1124



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 128/598 (21%), Positives = 196/598 (32%), Gaps = 113/598 (18%)

Query: 313  TNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPRE 372
            T E  SS+A +    Q       + T       P  PP    L +S        S S  +
Sbjct: 441  TPEAASSRAHRRHRRQAVFRRIKTRTASTPVNTPSRPPSSEFLDLS--------SASEDD 492

Query: 373  VESSPTQQETPGQPPEHHEVTVSPPGHH-----------------QTHHLASPSVSVKPP 415
             +S  ++QE  G    H   T S   HH                 +   L      V PP
Sbjct: 493  FDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPP 552

Query: 416  DVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDV-----EPPAIQHGGPPLLPESSEEAG 470
                    E   + G S  H   T R  GS + +     + PA   G    + E    +G
Sbjct: 553  PFMFKPVKE--EDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSG 610

Query: 471  ---PLAV-------QQETSFQSPEPINNENPSP-----TQQEAAAEHPQTAEEGESSLTH 515
               P A        + ET  +S + +  E  SP      Q+E  A   + A+   S  T 
Sbjct: 611  RNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTK 670

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLT-QATVQPLDL---------GFTITPESKTEVELSP 565
             +  ++ P  P+    +  +   +  + +  P D+               +++++ + S 
Sbjct: 671  TQEISR-PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSA 729

Query: 566  TMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP-VSPSVTVQLLDLGLTIT------ 618
              +    QPP    P   V    ++  PG  Q   P  +PS T        T +      
Sbjct: 730  QQQMLQAQPPALQAP-TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788

Query: 619  PEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMT 678
              PT  V H+   +   + P+ P    PHP    + H  L     QPL  G    P + +
Sbjct: 789  QAPTAPVPHTHIQQAPALHPQRP--PSPHPPPHPSPHPPL-----QPL-TGSAGQPSAPS 840

Query: 679  EVEPSTALMTTAPP-------------PGHPE-VTLPP-SDKGQAQHSHLTQATVQPLDL 723
              +P   L    PP             PG P+   LPP + +GQA       A      L
Sbjct: 841  HAQP--PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSL 898

Query: 724  ELTI------TTKPTTE--VKPSPTTEETSTQPPDLGLAIIPEPTTE------TGHSTAL 769
            +L        + +P  E  + P+P        PP   +  +P P         +G S   
Sbjct: 899  QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFS 958

Query: 770  EKTTAPRPDRVQTLHRSLT----EVTGPPTEL----EPAQDSLVQSESYTQNKALTAP 819
                 P P  ++ L    T        PP +L    +P   S  Q    TQ++ L  P
Sbjct: 959  MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 147/613 (23%), Positives = 202/613 (32%), Gaps = 101/613 (16%)

Query: 90   SASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKD---KLSPQERLPVS 146
            S   + PA P   T    P  +   S+G     P     S  D K    K S ++    +
Sbjct: 586  SGRKKQPASPDGRTS---PINEDIRSSGRN--SPSAASTSSNDSKAETVKKSAKKVKEEA 640

Query: 147  PKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGS-LPPELRVKSDE 205
               LK +  QR    E +    + +   S K+T   E S  ++P  G     + R  +DE
Sbjct: 641  SSPLKSNKRQR----EKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE 696

Query: 206  PPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALP 265
                 + +        P   +P+  E    SS QQ       Q+L+ +P ++Q      P
Sbjct: 697  GSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQ-------QMLQAQPPALQAPTGVTP 749

Query: 266  PESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQET 325
              SS              PPG  Q    LP     P+   V     PT    +SQA  + 
Sbjct: 750  APSSA-------------PPGTPQ----LPTPGPTPSATAVPPQGSPT----ASQAPNQP 788

Query: 326  PIQFPEEVEPSATQQEAP-IEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPG 384
              Q P    P    Q+AP + P  PP  H         P+QP        S+P+      
Sbjct: 789  --QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSH----A 842

Query: 385  QPPEHHEVTVSPPGHHQ------THHLASPSVSVKPPDVQLTIAAEPSAEVGTS--LVHQ 436
            QPP H +    PPG H         H   P     PP      A++  A +GTS    + 
Sbjct: 843  QPPLHGQ---GPPGPHSLQAGPLLQHPGPPQPFGLPPQ-----ASQGQAPLGTSPAAAYP 894

Query: 437  EATTRLSGSGNDVE-------------PPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP 483
              + +L  S + ++             P A+ H  PP      +   P A +       P
Sbjct: 895  HTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGP 954

Query: 484  EPIN---NENPSPTQQ---EAAAEHPQTAEEGESSLTHQ-----EAPAQTPEFPNVVVAQ 532
             P +   N  P P  +     +  HP +A      L  Q      +PAQ P         
Sbjct: 955  SPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLP 1014

Query: 533  PPEHSH----LTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGV 588
            PP  SH    L Q   QP        P     +   PT   T T P            G 
Sbjct: 1015 PPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI-TPPTCPSTSTPPAGPGTSAQPPCSGA 1073

Query: 589  TNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLP-H 647
                 G   A     P  TVQ+ +  L    EP      S PP     SP+   V  P H
Sbjct: 1074 A--ASGGSIAGGSSCPLPTVQIKEEALDDAEEP-----ESPPPPPRSPSPEPTVVDTPSH 1126

Query: 648  PDQVQTQHSHLTR 660
              Q    + HL R
Sbjct: 1127 ASQSARFYKHLDR 1139



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 145/670 (21%), Positives = 223/670 (33%), Gaps = 123/670 (18%)

Query: 118  EQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEI-IGITRQLSTPQSQ 176
            E+P++P  F+        K   +E   +S K   +    R S++ +  G  +Q ++P  +
Sbjct: 546  EKPVDPPPFMF-------KPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGR 598

Query: 177  KQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSS 236
               +  +  S+    P +        +      +E V  S   ++ E  +P     ++S+
Sbjct: 599  TSPINEDIRSSGRNSPSA------ASTSSNDSKAETVKKSAKKVKEEASSP-----LKSN 647

Query: 237  SLQQEAPA----QLPQLLEEEPSSMQQEAPALPPESSMESLTLP--NHEVSVQPPGEDQA 290
              Q+E  A    +  +   ++  + +   P  P E   ES      N E S  P   DQ 
Sbjct: 648  KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQD 707

Query: 291  YYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPP 350
                      P D E        ++++SS  QQ    Q P    P+         PP  P
Sbjct: 708  NRSTSPSIPSPQDNE--------SDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP 759

Query: 351  MEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ---THHLAS 407
                   +     V P  SP     +P Q + P  P  H  +  +P  H Q   + H   
Sbjct: 760  QLPTPGPTPSATAVPPQGSPT-ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH-PP 817

Query: 408  PSVSVKPPDVQLT-IAAEPSAEVGTSLVHQEATTRLSGSGND-----VEPPAIQHGGPP- 460
            P  S  PP   LT  A +PSA          A   L G G          P +QH GPP 
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAP-------SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870

Query: 461  ---LLPESSEEAGPL-----AVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESS 512
               L P++S+   PL     A    TS Q P        +   Q+   E P        +
Sbjct: 871  PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA----SQSALQSQQPPREQP--LPPAPLA 924

Query: 513  LTHQEAPAQTPEFPNVVVAQPPEHS-HLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
            + H + P  TP  P +   Q  +H  HL+  +   ++      P  K    LS     + 
Sbjct: 925  MPHIKPPPTTP-IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA 983

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
              PP +++PQ +         PG  Q+Q+                + P P      S PP
Sbjct: 984  HPPPLQLMPQSQPLPSSPAQPPGLTQSQN----------------LPPPPA-----SHPP 1022

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
                                    + L +   QP        P     + P T   T+ P
Sbjct: 1023 ------------------------TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 1058

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTE-ETSTQPPD 750
            P G      PP     A    +   +  PL         PT ++K     + E    PP 
Sbjct: 1059 PAGPGTSAQPPCSGAAASGGSIAGGSSCPL---------PTVQIKEEALDDAEEPESPPP 1109

Query: 751  LGLAIIPEPT 760
               +  PEPT
Sbjct: 1110 PPRSPSPEPT 1119



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 107/499 (21%), Positives = 158/499 (31%), Gaps = 82/499 (16%)

Query: 79   ADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLS 138
            +DP D D    S S  +P+P    +++        DS+ +Q +   Q  A Q       +
Sbjct: 699  SDPKDIDQDNRSTSPSIPSPQDNESDS--------DSSAQQQMLQAQPPALQAPTGVTPA 750

Query: 139  PQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE 198
            P    P +P+     P    +     G       P +Q Q        T      +L P+
Sbjct: 751  PSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAP-NQPQAPTAPVPHTHIQQAPALHPQ 809

Query: 199  LRVKSDEPPGPS-------------EQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQ 245
                   PP PS             +   PS        Q P     +Q+  L Q     
Sbjct: 810  RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP- 868

Query: 246  LPQLLEEEPSSMQQEAP------ALPPESSMESLTLPNHEVSVQPPGED---QAYYHLPN 296
             PQ     P + Q +AP      A  P +S++     +   S QPP E     A   +P+
Sbjct: 869  -PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH 927

Query: 297  ITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELS 356
            I   P        + P  +  + QA +      P    PS     A + P  PP    LS
Sbjct: 928  IKPPP--------TTPIPQLPAPQAHKHP----PHLSGPSPFSMNANLPP--PPALKPLS 973

Query: 357  ISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPD 416
                  P  PS  P  ++  P  Q  P  P +       PPG  Q+ +L  P  S  P  
Sbjct: 974  SLSTHHP--PSAHPPPLQLMPQSQPLPSSPAQ-------PPGLTQSQNLPPPPASHPPTG 1024

Query: 417  VQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQ 476
            +       P A                      + P +  G PP+ P +           
Sbjct: 1025 LHQVAPQPPFA----------------------QHPFVPGGPPPITPPTCPSTSTPPAGP 1062

Query: 477  ETSFQSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPN--VVVAQ 532
             TS Q P      +       ++   P  Q  EE        E+P   P  P+    V  
Sbjct: 1063 GTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVD 1122

Query: 533  PPEHSHLTQATVQPLDLGF 551
             P H+  +    + LD G+
Sbjct: 1123 TPSHASQSARFYKHLDRGY 1141



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 96/499 (19%), Positives = 153/499 (30%), Gaps = 73/499 (14%)

Query: 308  ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAP--IEPPVPPMEHELSISEQQQPV- 364
            +  E ++  +S++ Q+E      EE + +++++     I  P  P E E   S+ +    
Sbjct: 636  VKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVND 695

Query: 365  QPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAE 424
            + S  P++++            P+ +E         Q        +  +PP +Q      
Sbjct: 696  EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM-------LQAQPPALQAPTGVT 748

Query: 425  PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE 484
            P+         Q  T   + S   V P     G P      ++   P A    T  Q   
Sbjct: 749  PAPSSAPPGTPQLPTPGPTPSATAVPP----QGSPTASQAPNQPQAPTAPVPHTHIQQAP 804

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
             ++ + P        + HP         L      A  P  P+   AQPP H        
Sbjct: 805  ALHPQRPP-------SPHPPPHPSPHPPLQPLTGSAGQPSAPSH--AQPPLHGQ------ 849

Query: 545  QPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPG----QDQAQH 600
                      P     ++  P ++      P  + PQ    Q     +P         Q 
Sbjct: 850  ---------GPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQL 900

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            P S S             P     + H  PP      P  P   LP P Q      HL+ 
Sbjct: 901  PASQSALQSQQPPREQPLPPAPLAMPHIKPP------PTTPIPQLPAP-QAHKHPPHLSG 953

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
             +  P  +   + P     ++P ++L T  PP  H     PP  +   Q   L  +  QP
Sbjct: 954  PS--PFSMNANLPPPPA--LKPLSSLSTHHPPSAH-----PPPLQLMPQSQPLPSSPAQP 1004

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
              L  +    P     P     + + QPP      +P                 P P   
Sbjct: 1005 PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP---------------GGPPPITP 1049

Query: 781  QTLHRSLTEVTGPPTELEP 799
             T   + T   GP T  +P
Sbjct: 1050 PTCPSTSTPPAGPGTSAQP 1068



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 87/351 (24%), Positives = 119/351 (33%), Gaps = 64/351 (18%)

Query: 46   PLQLTSNPLGPPESWSSHSSHFPRESPHAP-TLPADPWDFDHLGPSASSEMPAPPQESTE 104
            PLQ  +   G P + S        + P  P +L A P    H GP     +P  PQ S +
Sbjct: 825  PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL-LQHPGPPQPFGLP--PQAS-Q 880

Query: 105  NLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEII 164
               P L T   A   P    Q  ASQ  L+ +  P+E+ P+ P  L     +      I 
Sbjct: 881  GQAP-LGT-SPAAAYPHTSLQLPASQSALQSQQPPREQ-PLPPAPLAMPHIKPPPTTPI- 936

Query: 165  GITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPET 224
                QL  PQ+ K                  PP L              GPS F +    
Sbjct: 937  ---PQLPAPQAHKH-----------------PPHLS-------------GPSPFSMNANL 963

Query: 225  QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPN------- 277
              P  L+ + S S      A  P L     S     +PA PP    +S  LP        
Sbjct: 964  PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP-GLTQSQNLPPPPASHPP 1022

Query: 278  ---HEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFP-EEV 333
               H+V+ QPP     +   P +   P      IT      T +  A   T  Q P    
Sbjct: 1023 TGLHQVAPQPP-----FAQHPFVPGGPP----PITPPTCPSTSTPPAGPGTSAQPPCSGA 1073

Query: 334  EPSATQQEAPIEPPVPPME-HELSISEQQQPVQPSESPREVESSPTQQETP 383
              S          P+P ++  E ++ + ++P  P   PR     PT  +TP
Sbjct: 1074 AASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 1124



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 128/598 (21%), Positives = 196/598 (32%), Gaps = 113/598 (18%)

Query: 313  TNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPRE 372
            T E  SS+A +    Q       + T       P  PP    L +S        S S  +
Sbjct: 441  TPEAASSRAHRRHRRQAVFRRIKTRTASTPVNTPSRPPSSEFLDLS--------SASEDD 492

Query: 373  VESSPTQQETPGQPPEHHEVTVSPPGHH-----------------QTHHLASPSVSVKPP 415
             +S  ++QE  G    H   T S   HH                 +   L      V PP
Sbjct: 493  FDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPP 552

Query: 416  DVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDV-----EPPAIQHGGPPLLPESSEEAG 470
                    E   + G S  H   T R  GS + +     + PA   G    + E    +G
Sbjct: 553  PFMFKPVKE--EDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSG 610

Query: 471  ---PLAV-------QQETSFQSPEPINNENPSP-----TQQEAAAEHPQTAEEGESSLTH 515
               P A        + ET  +S + +  E  SP      Q+E  A   + A+   S  T 
Sbjct: 611  RNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTK 670

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLT-QATVQPLDL---------GFTITPESKTEVELSP 565
             +  ++ P  P+    +  +   +  + +  P D+               +++++ + S 
Sbjct: 671  TQEISR-PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSA 729

Query: 566  TMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP-VSPSVTVQLLDLGLTIT------ 618
              +    QPP    P   V    ++  PG  Q   P  +PS T        T +      
Sbjct: 730  QQQMLQAQPPALQAP-TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788

Query: 619  PEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMT 678
              PT  V H+   +   + P+ P    PHP    + H  L     QPL  G    P + +
Sbjct: 789  QAPTAPVPHTHIQQAPALHPQRP--PSPHPPPHPSPHPPL-----QPL-TGSAGQPSAPS 840

Query: 679  EVEPSTALMTTAPP-------------PGHPE-VTLPP-SDKGQAQHSHLTQATVQPLDL 723
              +P   L    PP             PG P+   LPP + +GQA       A      L
Sbjct: 841  HAQP--PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSL 898

Query: 724  ELTI------TTKPTTE--VKPSPTTEETSTQPPDLGLAIIPEPTTE------TGHSTAL 769
            +L        + +P  E  + P+P        PP   +  +P P         +G S   
Sbjct: 899  QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFS 958

Query: 770  EKTTAPRPDRVQTLHRSLT----EVTGPPTEL----EPAQDSLVQSESYTQNKALTAP 819
                 P P  ++ L    T        PP +L    +P   S  Q    TQ++ L  P
Sbjct: 959  MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 142/628 (22%), Positives = 217/628 (34%), Gaps = 87/628 (13%)

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
            D Q++ L+ +APA   +     P  + Q+     PES + SL L   E+ + P G +   
Sbjct: 725  DYQATLLEDQAPAHFHRNF---PEQVFQDLQRKSPESEILSLHLLVEELRLNPDGVE--- 778

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  TV     E+ + S    E E   +     I FPE+    A   E  +E  +P +
Sbjct: 779  ------TVNDTKPELNVASSEGGEMERRDSDSFLNI-FPEKQVTKAGNTEPVLEEWIPVL 831

Query: 352  EHEL------SISEQQQPVQPS-ESPREVESSPTQQETPG----QPPEHHEVTVSPPGHH 400
            +         ++ +      PS E    + + P  + T       P  H ++ V+     
Sbjct: 832  QRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSL 891

Query: 401  QTHHLAS-----------PSVSVKPPDVQLTIAA----EPSAEVGTSLVHQEATTRLSGS 445
            +   + +           P+V+V  P+    +AA    E +A    + + QE  + ++G 
Sbjct: 892  EEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGF 951

Query: 446  GNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP-EPINNENPSPTQQEAAAEHPQ 504
              +    AI     P+  E     GP  V   T+  +P EP        T +E A+  P 
Sbjct: 952  SPEWAALAIT---VPITEEDGTPEGP--VTPATTVHAPEEPDTAAVRVSTPEEPAS--PA 1004

Query: 505  TAEEGESSLTHQEAPAQTPEFP-NVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVEL 563
             A       T   A   TPE P +   A PP     + A   P       TPE  T    
Sbjct: 1005 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVP-------TPEEPTSPAA 1057

Query: 564  SPTMKETPTQPPKKV-VPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPT 622
            +    E PT P   V  P+         PTP     + P SP+  V         TPE  
Sbjct: 1058 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP-----EEPTSPAAAVP--------TPEEP 1104

Query: 623  TEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEP 682
            T    + P   T   P  P   +P P++  +       A   P +  F        E   
Sbjct: 1105 TSPAAAVP---TPEEPASPAAAVPTPEEPASP----AAAVPTPEEPAFPAPAVPTPEESA 1157

Query: 683  STALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTK----PTTEVKPS 738
            S A+    P          P+    A  + +     +P     ++ T      T E   S
Sbjct: 1158 SAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTS 1217

Query: 739  PTTE-ETSTQPPDLGLAII--PEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPT 795
            P     TS +P  L  A+    EPT+       LE+ T+     V T     +     PT
Sbjct: 1218 PAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAA-AVLTPEELSSPAASVPT 1276

Query: 796  ELEPAQDSLVQS---ESYTQNKALTAPE 820
              EPA  +   S   E  +   A+  PE
Sbjct: 1277 PEEPASPAAAVSNLEEPASPAAAVPTPE 1304



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 90/376 (23%), Positives = 129/376 (34%), Gaps = 51/376 (13%)

Query: 169  QLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPE 228
            ++STP+          ++  TP   + P       +EP  P+  V P +    P    P 
Sbjct: 993  RVSTPEEPASPA----AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVP- 1047

Query: 229  TLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGED 288
            T E+  S +     P        EEP+S     P  P E +  +  +P  E    P    
Sbjct: 1048 TPEEPTSPAAAVPTP--------EEPTSPAAAVPT-PEEPTSPAAAVPTPEEPTSPA--- 1095

Query: 289  QAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV 348
             A    P     PA       + PT E  +S A     +  PEE    A     P EP  
Sbjct: 1096 -AAVPTPEEPTSPA------AAVPTPEEPASPA---AAVPTPEEPASPAAAVPTPEEPAF 1145

Query: 349  P----PMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHH 404
            P    P   E + +    P  P ES     + PT  E+          T+  P       
Sbjct: 1146 PAPAVPTPEESASAAVAVPT-PEESASPAAAVPTPAESASFAAV--VATLEEP------- 1195

Query: 405  LASPSVSVKPPDVQLTIAAE---PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPL 461
              SP+ SV  P   +    E   P+A V TS   +E  +  +   N  EP +     P L
Sbjct: 1196 -TSPAASVPTPAAMVATLEEFTSPAASVPTS---EEPASLAAAVSNPEEPTSPAAAVPTL 1251

Query: 462  LPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPA- 520
               +S  A  L  ++ +S  +  P   E  SP    +  E P +      +      PA 
Sbjct: 1252 EEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAA 1311

Query: 521  --QTPEFPNVVVAQPP 534
               TPE P +  A  P
Sbjct: 1312 SVPTPEVPAIPAAAVP 1327


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 122/502 (24%), Positives = 181/502 (36%), Gaps = 75/502 (14%)

Query: 304  VEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQP 363
            V  T  SE T  TE+     + P    E+   +  +   P E P  P E     +E  +P
Sbjct: 548  VSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTE--KP 605

Query: 364  VQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAA 423
              PSE P      PT    P + P       + P    T     P++S + P V      
Sbjct: 606  TIPSEKPNMPSEKPT---IPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPT 662

Query: 424  EPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP 483
             P+ E  TS+  +E            E P+I    P   P  S E   ++ ++ T     
Sbjct: 663  TPTEETTTSM--EEPVIPTEKPSIPTEKPSI----PTEKPTISMEETIISTEKPTISPEK 716

Query: 484  EPINNENPS-PTQQEA-AAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQ 541
              I  E P+ PT++   + E P T  E  +  T  E P  +PE P     +P        
Sbjct: 717  PTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPT--EKPTISPEKPTTPTEKP-------- 766

Query: 542  ATVQPLDLGFTITPESKTEVELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
                      TI+PE  T     PT+  E PT P +K  P +   +     TP ++    
Sbjct: 767  ----------TISPEKLTIPTEKPTIPTEKPTIPTEK--PTISTEEPT---TPTEETTIS 811

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHST--------PPKRTIVSPKHPEVTLP------ 646
               PS+ ++   L    T E TT V  +T        P ++  +S + P  T+P      
Sbjct: 812  TEKPSIPMEKPTLP---TEETTTSVEETTISTEKLTIPMEKPTISTEKP--TIPTEKPTI 866

Query: 647  HPDQVQTQHSHLTRATVQP--------LDLGFTITPKSMTEVEPSTALMTTAPPPGHPEV 698
             P+++      LT  T +P        +       P     + P    ++T  P    E 
Sbjct: 867  SPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEK 926

Query: 699  TLPPSDKGQAQHSHLTQATVQPL--DLELTI-TTKPTTEVKPSPTTEETSTQPPDLGLAI 755
               P+++       LT  T +P     +LTI T KPT   +      E  T P +     
Sbjct: 927  PTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIP 986

Query: 756  IPEPTTETGHSTALEKTTAPRP 777
              +PT  T      EK TA RP
Sbjct: 987  TEKPTIPT------EKLTALRP 1002



 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 126/557 (22%), Positives = 203/557 (36%), Gaps = 89/557 (15%)

Query: 135  DKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGS 194
            +K S     P  PK+    P ++ +      I+ +  T  S+K  + +E  +  +  P  
Sbjct: 575  EKPSVTTEKPTVPKEKPTIPTEKPT------ISTEKPTIPSEKPNMPSEKPTIPSEKPTI 628

Query: 195  LPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEA-PAQLPQLLEEE 253
            L  +  + S++P  PSE+   S       T+ P T  +  ++S+++   P + P +  E+
Sbjct: 629  LTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEK 688

Query: 254  PSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
            PS      P   P  SME   +   + ++ P          P I           T +PT
Sbjct: 689  PS-----IPTEKPTISMEETIISTEKPTISP--------EKPTIP----------TEKPT 725

Query: 314  NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREV 373
              TE S    E P    E  +P+   ++  I P  P    E      ++   P+E P   
Sbjct: 726  IPTEKSTISPEKPTTPTE--KPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP--- 780

Query: 374  ESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL 433
             + PT  E P  P E   ++   P    T      ++S + P + +     P+ E  TS+
Sbjct: 781  -TIPT--EKPTIPTEKPTISTEEP----TTPTEETTISTEKPSIPMEKPTLPTEETTTSV 833

Query: 434  VHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSP 493
              +E T         +E P I    P +      E   ++ ++ T       I  E P+ 
Sbjct: 834  --EETTISTEKLTIPMEKPTISTEKPTI----PTEKPTISPEKLTIPTEKLTIPTEKPTI 887

Query: 494  TQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGF-- 551
              +E      +     E      E P  + E P +   +P   +  T  + + L +    
Sbjct: 888  PIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEK 947

Query: 552  -TITPESKTEVELSPTMK-ETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQ 609
             TI+PE  T     PT+  E PT P +K          +T PT      + P  P     
Sbjct: 948  PTISPEKLTIPTEKPTISTEKPTIPTEK----------LTIPT------EKPTIP----- 986

Query: 610  LLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPH-PDQVQTQHSHLTRATVQPLDL 668
                    T +PT         K T + P HP  T       V + H+  T  T   + L
Sbjct: 987  --------TEKPTIPT-----EKLTALRPPHPSPTATGLAALVMSPHAPSTPMT--SVIL 1031

Query: 669  GFTITPKSMTEVEPSTA 685
            G T T +S TE  P  A
Sbjct: 1032 GTTTTSRSSTERCPPNA 1048



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 97/423 (22%), Positives = 164/423 (38%), Gaps = 55/423 (13%)

Query: 34  VKEAQPLEWVKDPLQLTSNPLGPPE--SWSSHSSHFPRESP-----------HAPTLPAD 80
           V + +P    + P   T  P  P E  +  S     P E P             PT+P++
Sbjct: 586 VPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSE 645

Query: 81  PWDFDHLGPSASSEMPAPPQESTENLV--PFLDTWDSA--GEQPLEP--------EQFLA 128
                   P+  +E P  P E T   +  P + T   +   E+P  P        E+ + 
Sbjct: 646 KPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETII 705

Query: 129 SQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLA-EIIGITRQLSTPQSQKQTLQNEYSST 187
           S +  K  +SP++  P  P +    P ++ +++ E      +  T  ++K T+  E  +T
Sbjct: 706 STE--KPTISPEK--PTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT 761

Query: 188 DTPYPGSLPPELRVKSDEPPGPSEQ-----VGPSQFHLEPETQNPETLEDIQSSSLQQEA 242
            T  P   P +L + +++P  P+E+       P+    EP T   ET    +  S+  E 
Sbjct: 762 PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEK 821

Query: 243 PAQLPQLLEEEPSSMQQEA--------PALPPESSMESLTLPNHEVSVQPPGEDQAYYHL 294
           P  LP   EE  +S+++          P   P  S E  T+P  + ++ P   ++     
Sbjct: 822 PT-LP--TEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISP---EKLTIPT 875

Query: 295 PNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHE 354
             +T+ P +       E T  TE      E P   PE+   S  +   P E P  P E E
Sbjct: 876 EKLTI-PTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTE-E 933

Query: 355 LSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKP 414
            +IS ++  + P+E P     SP +   P + P       + P    T     P++  + 
Sbjct: 934 TTISTEKLTI-PTEKP---TISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEK 989

Query: 415 PDV 417
           P +
Sbjct: 990 PTI 992



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 111/525 (21%), Positives = 180/525 (34%), Gaps = 91/525 (17%)

Query: 68   PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFL 127
            P  +   PT+P +        P+ S+E P  P E            +   E+P  P +  
Sbjct: 577  PSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKP----------NMPSEKPTIPSE-- 624

Query: 128  ASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSST 187
                               P  L + P           I  +  T  S+K T+  E  + 
Sbjct: 625  ------------------KPTILTEKPT----------IPSEKPTIPSEKPTISTEKPTV 656

Query: 188  DTPYPGSLPPELRVKSDEPPGPSEQVG-PSQFHLEPETQNPETLEDIQSSSLQQEAPAQL 246
             T  P +   E     +EP  P+E+   P++    P  +   ++E+   S+ +     + 
Sbjct: 657  PTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEK 716

Query: 247  PQLLEEEPSSMQQEAPALP--PESSMESLTLPNHEVSVQP-----PGEDQAYYHLPNITV 299
            P +  E+P+   +++   P  P +  E  T+P  + ++ P     P E       P    
Sbjct: 717  PTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTI--SPEKLT 774

Query: 300  KPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISE 359
             P +     T +PT  TE      E P    EE   S  +   P+E P  P E E + S 
Sbjct: 775  IPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTE-ETTTSV 833

Query: 360  QQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQL 419
            ++  +   +    +E      E P  P E  + T+SP        L  P+  +  P  + 
Sbjct: 834  EETTISTEKLTIPMEKPTISTEKPTIPTE--KPTISP------EKLTIPTEKLTIPTEKP 885

Query: 420  TIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGP------PLLP--ESSEEAGP 471
            TI  E      T++  ++ T          E P I    P      P +P  E++     
Sbjct: 886  TIPIEE-----TTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEK 940

Query: 472  LAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEA-PAQTPEFP--NV 528
            L +  E    SPE +      PT    + E P    E  +  T +   P + P  P   +
Sbjct: 941  LTIPTEKPTISPEKLTIPTEKPT---ISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKL 997

Query: 529  VVAQPPEHS-------------HLTQATVQPLDLGFTITPESKTE 560
               +PP  S             H     +  + LG T T  S TE
Sbjct: 998  TALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTE 1042



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 92/394 (23%), Positives = 146/394 (37%), Gaps = 72/394 (18%)

Query: 64   SSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP-LE 122
            S+  P  SP  PT+P +         + S E P  P E      P + T     E+P + 
Sbjct: 706  STEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK-----PTIPT-----EKPTIS 755

Query: 123  PEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQN 182
            PE+            +P E+  +SP+KL               I  +  T  ++K T+  
Sbjct: 756  PEK----------PTTPTEKPTISPEKLT--------------IPTEKPTIPTEKPTIPT 791

Query: 183  EYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQE- 241
            E  +  T  P +   E  + +++P  P E         +P     ET   ++ +++  E 
Sbjct: 792  EKPTISTEEPTTPTEETTISTEKPSIPME---------KPTLPTEETTTSVEETTISTEK 842

Query: 242  --APAQLPQLLEEEPSSMQQEAPALPPES---SMESLTLPNHEVSVQPPGEDQAYYHLPN 296
               P + P +  E+P ++  E P + PE      E LT+P  + ++       +   L  
Sbjct: 843  LTIPMEKPTISTEKP-TIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTI 901

Query: 297  ITVKPADVEVTITSE-PTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPP-------- 347
             T KP     TI+ E PT  TE      E P    EE   S  +   P E P        
Sbjct: 902  PTEKP-----TISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLT 956

Query: 348  VPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLAS 407
            +P  +  +S  +   P +    P E  + PT  E P  P E       P        LA+
Sbjct: 957  IPTEKPTISTEKPTIPTEKLTIPTEKPTIPT--EKPTIPTEKLTALRPPHPSPTATGLAA 1014

Query: 408  PSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTR 441
              +S   P   +T     S  +GT+   + +T R
Sbjct: 1015 LVMSPHAPSTPMT-----SVILGTTTTSRSSTER 1043



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 91/398 (22%), Positives = 148/398 (37%), Gaps = 53/398 (13%)

Query: 459 PPLLPESSEEAGP---LAVQQETSFQSPEP-INNENPSPTQQEAAAEHPQTAEEGESSLT 514
           PP+ P SS   GP     + +  +  + +P ++ E PS T ++      +     E    
Sbjct: 543 PPVSPVSS--TGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI 600

Query: 515 HQEAPAQTPEFPNVVVAQPPEHSHL-TQATVQPLDLGFTITPESKTEVELSPTMK-ETPT 572
             E P    E PN+   +P   S   T  T +P     TI  E  T     PT+  E PT
Sbjct: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKP-----TIPSEKPTIPSEKPTISTEKPT 655

Query: 573 QPPKK-VVPQLRVYQGVTNPTPGQDQAQHPVS-PSVTVQLLDLGL----------TITPE 620
            P ++   P       +  P    ++   P   PS+  +   + +          TI+PE
Sbjct: 656 VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPE 715

Query: 621 -PTTEVGHST-PPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMT 678
            PT      T P +++ +SP+ P      P  + T+     + T+ P       TP    
Sbjct: 716 KPTIPTEKPTIPTEKSTISPEKPTTPTEKPT-IPTE-----KPTISPEK---PTTPTEKP 766

Query: 679 EVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITT--------K 730
            + P    + T  P    E    P++K        T  T      E TI+T        K
Sbjct: 767 TISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTE-----ETTISTEKPSIPMEK 821

Query: 731 PTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEV 790
           PT   + + T+ E +T   +     + +PT  T   T   +     P+++      LT  
Sbjct: 822 PTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIP 881

Query: 791 TGPPTELEPAQDSLVQSESYT--QNKALTAPEEHKAST 826
           T  PT   P +++ + +E  T    K   +PE+   ST
Sbjct: 882 TEKPT--IPIEETTISTEKLTIPTEKPTISPEKPTIST 917



 Score = 31.2 bits (69), Expect = 9.0
 Identities = 73/340 (21%), Positives = 117/340 (34%), Gaps = 46/340 (13%)

Query: 520 AQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKT-EVELSPTMKETPTQPPKKV 578
           +Q P + N  V  P  H        QP+ L F     S T  V     +   P   P KV
Sbjct: 486 SQRPYWQNTSVTVPSGHQ-------QPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKV 538

Query: 579 VPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSP 638
           +P+L     V++  P +      ++ + T+      ++I     T    + P ++  +  
Sbjct: 539 LPELPPVSPVSSTGPSETTG---LTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPT 595

Query: 639 KHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPST------ALMTTAPP 692
           + P ++   P     + +  +     P +    +T K     E  T       + T  P 
Sbjct: 596 EKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPT 655

Query: 693 PGHPEVTLP-------------PSDKGQAQHSHLTQATVQP-LDLELTI--TTKPTTEVK 736
               E T P             P++K        +  T +P + +E TI  T KPT   +
Sbjct: 656 VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPE 715

Query: 737 PSPTTEETSTQPPDLGLAIIPEPTTETGHST--------ALEKTTAPRPDRVQTLHRSLT 788
                 E  T P +       +PTT T   T        + EK T P  ++       LT
Sbjct: 716 KPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-TEKPTISPEKLT 774

Query: 789 EVTGPPTELEPAQDSLVQSESYT--QNKALTAPEEHKAST 826
             T  PT   P +   + +E  T    +  T  EE   ST
Sbjct: 775 IPTEKPT--IPTEKPTIPTEKPTISTEEPTTPTEETTIST 812


>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
          Length = 2721

 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 122/502 (24%), Positives = 181/502 (36%), Gaps = 75/502 (14%)

Query: 304  VEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQP 363
            V  T  SE T  TE+     + P    E+   +  +   P E P  P E     +E  +P
Sbjct: 548  VSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTE--KP 605

Query: 364  VQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAA 423
              PSE P      PT    P + P       + P    T     P++S + P V      
Sbjct: 606  TIPSEKPNMPSEKPT---IPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPT 662

Query: 424  EPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP 483
             P+ E  TS+  +E            E P+I    P   P  S E   ++ ++ T     
Sbjct: 663  TPTEETTTSM--EEPVIPTEKPSIPTEKPSI----PTEKPTISMEETIISTEKPTISPEK 716

Query: 484  EPINNENPS-PTQQEA-AAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQ 541
              I  E P+ PT++   + E P T  E  +  T  E P  +PE P     +P        
Sbjct: 717  PTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPT--EKPTISPEKPTTPTEKP-------- 766

Query: 542  ATVQPLDLGFTITPESKTEVELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
                      TI+PE  T     PT+  E PT P +K  P +   +     TP ++    
Sbjct: 767  ----------TISPEKLTIPTEKPTIPTEKPTIPTEK--PTISTEEPT---TPTEETTIS 811

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHST--------PPKRTIVSPKHPEVTLP------ 646
               PS+ ++   L    T E TT V  +T        P ++  +S + P  T+P      
Sbjct: 812  TEKPSIPMEKPTLP---TEETTTSVEETTISTEKLTIPMEKPTISTEKP--TIPTEKPTI 866

Query: 647  HPDQVQTQHSHLTRATVQP--------LDLGFTITPKSMTEVEPSTALMTTAPPPGHPEV 698
             P+++      LT  T +P        +       P     + P    ++T  P    E 
Sbjct: 867  SPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEK 926

Query: 699  TLPPSDKGQAQHSHLTQATVQPL--DLELTI-TTKPTTEVKPSPTTEETSTQPPDLGLAI 755
               P+++       LT  T +P     +LTI T KPT   +      E  T P +     
Sbjct: 927  PTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIP 986

Query: 756  IPEPTTETGHSTALEKTTAPRP 777
              +PT  T      EK TA RP
Sbjct: 987  TEKPTIPT------EKLTALRP 1002



 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 126/557 (22%), Positives = 203/557 (36%), Gaps = 89/557 (15%)

Query: 135  DKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGS 194
            +K S     P  PK+    P ++ +      I+ +  T  S+K  + +E  +  +  P  
Sbjct: 575  EKPSVTTEKPTVPKEKPTIPTEKPT------ISTEKPTIPSEKPNMPSEKPTIPSEKPTI 628

Query: 195  LPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEA-PAQLPQLLEEE 253
            L  +  + S++P  PSE+   S       T+ P T  +  ++S+++   P + P +  E+
Sbjct: 629  LTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEK 688

Query: 254  PSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
            PS      P   P  SME   +   + ++ P          P I           T +PT
Sbjct: 689  PS-----IPTEKPTISMEETIISTEKPTISP--------EKPTIP----------TEKPT 725

Query: 314  NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREV 373
              TE S    E P    E  +P+   ++  I P  P    E      ++   P+E P   
Sbjct: 726  IPTEKSTISPEKPTTPTE--KPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP--- 780

Query: 374  ESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL 433
             + PT  E P  P E   ++   P    T      ++S + P + +     P+ E  TS+
Sbjct: 781  -TIPT--EKPTIPTEKPTISTEEP----TTPTEETTISTEKPSIPMEKPTLPTEETTTSV 833

Query: 434  VHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSP 493
              +E T         +E P I    P +      E   ++ ++ T       I  E P+ 
Sbjct: 834  --EETTISTEKLTIPMEKPTISTEKPTI----PTEKPTISPEKLTIPTEKLTIPTEKPTI 887

Query: 494  TQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGF-- 551
              +E      +     E      E P  + E P +   +P   +  T  + + L +    
Sbjct: 888  PIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEK 947

Query: 552  -TITPESKTEVELSPTMK-ETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQ 609
             TI+PE  T     PT+  E PT P +K          +T PT      + P  P     
Sbjct: 948  PTISPEKLTIPTEKPTISTEKPTIPTEK----------LTIPT------EKPTIP----- 986

Query: 610  LLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPH-PDQVQTQHSHLTRATVQPLDL 668
                    T +PT         K T + P HP  T       V + H+  T  T   + L
Sbjct: 987  --------TEKPTIPT-----EKLTALRPPHPSPTATGLAALVMSPHAPSTPMT--SVIL 1031

Query: 669  GFTITPKSMTEVEPSTA 685
            G T T +S TE  P  A
Sbjct: 1032 GTTTTSRSSTERCPPNA 1048



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 97/423 (22%), Positives = 164/423 (38%), Gaps = 55/423 (13%)

Query: 34  VKEAQPLEWVKDPLQLTSNPLGPPE--SWSSHSSHFPRESP-----------HAPTLPAD 80
           V + +P    + P   T  P  P E  +  S     P E P             PT+P++
Sbjct: 586 VPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSE 645

Query: 81  PWDFDHLGPSASSEMPAPPQESTENLV--PFLDTWDSA--GEQPLEP--------EQFLA 128
                   P+  +E P  P E T   +  P + T   +   E+P  P        E+ + 
Sbjct: 646 KPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETII 705

Query: 129 SQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLA-EIIGITRQLSTPQSQKQTLQNEYSST 187
           S +  K  +SP++  P  P +    P ++ +++ E      +  T  ++K T+  E  +T
Sbjct: 706 STE--KPTISPEK--PTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT 761

Query: 188 DTPYPGSLPPELRVKSDEPPGPSEQ-----VGPSQFHLEPETQNPETLEDIQSSSLQQEA 242
            T  P   P +L + +++P  P+E+       P+    EP T   ET    +  S+  E 
Sbjct: 762 PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEK 821

Query: 243 PAQLPQLLEEEPSSMQQEA--------PALPPESSMESLTLPNHEVSVQPPGEDQAYYHL 294
           P  LP   EE  +S+++          P   P  S E  T+P  + ++ P   ++     
Sbjct: 822 PT-LP--TEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISP---EKLTIPT 875

Query: 295 PNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHE 354
             +T+ P +       E T  TE      E P   PE+   S  +   P E P  P E E
Sbjct: 876 EKLTI-PTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTE-E 933

Query: 355 LSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKP 414
            +IS ++  + P+E P     SP +   P + P       + P    T     P++  + 
Sbjct: 934 TTISTEKLTI-PTEKP---TISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEK 989

Query: 415 PDV 417
           P +
Sbjct: 990 PTI 992



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 111/525 (21%), Positives = 180/525 (34%), Gaps = 91/525 (17%)

Query: 68   PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFL 127
            P  +   PT+P +        P+ S+E P  P E            +   E+P  P +  
Sbjct: 577  PSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKP----------NMPSEKPTIPSE-- 624

Query: 128  ASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSST 187
                               P  L + P           I  +  T  S+K T+  E  + 
Sbjct: 625  ------------------KPTILTEKPT----------IPSEKPTIPSEKPTISTEKPTV 656

Query: 188  DTPYPGSLPPELRVKSDEPPGPSEQVG-PSQFHLEPETQNPETLEDIQSSSLQQEAPAQL 246
             T  P +   E     +EP  P+E+   P++    P  +   ++E+   S+ +     + 
Sbjct: 657  PTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEK 716

Query: 247  PQLLEEEPSSMQQEAPALP--PESSMESLTLPNHEVSVQP-----PGEDQAYYHLPNITV 299
            P +  E+P+   +++   P  P +  E  T+P  + ++ P     P E       P    
Sbjct: 717  PTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTI--SPEKLT 774

Query: 300  KPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISE 359
             P +     T +PT  TE      E P    EE   S  +   P+E P  P E E + S 
Sbjct: 775  IPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTE-ETTTSV 833

Query: 360  QQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQL 419
            ++  +   +    +E      E P  P E  + T+SP        L  P+  +  P  + 
Sbjct: 834  EETTISTEKLTIPMEKPTISTEKPTIPTE--KPTISP------EKLTIPTEKLTIPTEKP 885

Query: 420  TIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGP------PLLP--ESSEEAGP 471
            TI  E      T++  ++ T          E P I    P      P +P  E++     
Sbjct: 886  TIPIEE-----TTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEK 940

Query: 472  LAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEA-PAQTPEFP--NV 528
            L +  E    SPE +      PT    + E P    E  +  T +   P + P  P   +
Sbjct: 941  LTIPTEKPTISPEKLTIPTEKPT---ISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKL 997

Query: 529  VVAQPPEHS-------------HLTQATVQPLDLGFTITPESKTE 560
               +PP  S             H     +  + LG T T  S TE
Sbjct: 998  TALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTE 1042



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 92/394 (23%), Positives = 146/394 (37%), Gaps = 72/394 (18%)

Query: 64   SSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP-LE 122
            S+  P  SP  PT+P +         + S E P  P E      P + T     E+P + 
Sbjct: 706  STEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK-----PTIPT-----EKPTIS 755

Query: 123  PEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQN 182
            PE+            +P E+  +SP+KL               I  +  T  ++K T+  
Sbjct: 756  PEK----------PTTPTEKPTISPEKLT--------------IPTEKPTIPTEKPTIPT 791

Query: 183  EYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQE- 241
            E  +  T  P +   E  + +++P  P E         +P     ET   ++ +++  E 
Sbjct: 792  EKPTISTEEPTTPTEETTISTEKPSIPME---------KPTLPTEETTTSVEETTISTEK 842

Query: 242  --APAQLPQLLEEEPSSMQQEAPALPPES---SMESLTLPNHEVSVQPPGEDQAYYHLPN 296
               P + P +  E+P ++  E P + PE      E LT+P  + ++       +   L  
Sbjct: 843  LTIPMEKPTISTEKP-TIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTI 901

Query: 297  ITVKPADVEVTITSE-PTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPP-------- 347
             T KP     TI+ E PT  TE      E P    EE   S  +   P E P        
Sbjct: 902  PTEKP-----TISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLT 956

Query: 348  VPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLAS 407
            +P  +  +S  +   P +    P E  + PT  E P  P E       P        LA+
Sbjct: 957  IPTEKPTISTEKPTIPTEKLTIPTEKPTIPT--EKPTIPTEKLTALRPPHPSPTATGLAA 1014

Query: 408  PSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTR 441
              +S   P   +T     S  +GT+   + +T R
Sbjct: 1015 LVMSPHAPSTPMT-----SVILGTTTTSRSSTER 1043



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 91/398 (22%), Positives = 148/398 (37%), Gaps = 53/398 (13%)

Query: 459 PPLLPESSEEAGP---LAVQQETSFQSPEP-INNENPSPTQQEAAAEHPQTAEEGESSLT 514
           PP+ P SS   GP     + +  +  + +P ++ E PS T ++      +     E    
Sbjct: 543 PPVSPVSS--TGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI 600

Query: 515 HQEAPAQTPEFPNVVVAQPPEHSHL-TQATVQPLDLGFTITPESKTEVELSPTMK-ETPT 572
             E P    E PN+   +P   S   T  T +P     TI  E  T     PT+  E PT
Sbjct: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKP-----TIPSEKPTIPSEKPTISTEKPT 655

Query: 573 QPPKK-VVPQLRVYQGVTNPTPGQDQAQHPVS-PSVTVQLLDLGL----------TITPE 620
            P ++   P       +  P    ++   P   PS+  +   + +          TI+PE
Sbjct: 656 VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPE 715

Query: 621 -PTTEVGHST-PPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMT 678
            PT      T P +++ +SP+ P      P  + T+     + T+ P       TP    
Sbjct: 716 KPTIPTEKPTIPTEKSTISPEKPTTPTEKPT-IPTE-----KPTISPEK---PTTPTEKP 766

Query: 679 EVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITT--------K 730
            + P    + T  P    E    P++K        T  T      E TI+T        K
Sbjct: 767 TISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTE-----ETTISTEKPSIPMEK 821

Query: 731 PTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEV 790
           PT   + + T+ E +T   +     + +PT  T   T   +     P+++      LT  
Sbjct: 822 PTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIP 881

Query: 791 TGPPTELEPAQDSLVQSESYT--QNKALTAPEEHKAST 826
           T  PT   P +++ + +E  T    K   +PE+   ST
Sbjct: 882 TEKPT--IPIEETTISTEKLTIPTEKPTISPEKPTIST 917



 Score = 31.2 bits (69), Expect = 9.0
 Identities = 73/340 (21%), Positives = 117/340 (34%), Gaps = 46/340 (13%)

Query: 520 AQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKT-EVELSPTMKETPTQPPKKV 578
           +Q P + N  V  P  H        QP+ L F     S T  V     +   P   P KV
Sbjct: 486 SQRPYWQNTSVTVPSGHQ-------QPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKV 538

Query: 579 VPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSP 638
           +P+L     V++  P +      ++ + T+      ++I     T    + P ++  +  
Sbjct: 539 LPELPPVSPVSSTGPSETTG---LTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPT 595

Query: 639 KHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPST------ALMTTAPP 692
           + P ++   P     + +  +     P +    +T K     E  T       + T  P 
Sbjct: 596 EKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPT 655

Query: 693 PGHPEVTLP-------------PSDKGQAQHSHLTQATVQP-LDLELTI--TTKPTTEVK 736
               E T P             P++K        +  T +P + +E TI  T KPT   +
Sbjct: 656 VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPE 715

Query: 737 PSPTTEETSTQPPDLGLAIIPEPTTETGHST--------ALEKTTAPRPDRVQTLHRSLT 788
                 E  T P +       +PTT T   T        + EK T P  ++       LT
Sbjct: 716 KPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-TEKPTISPEKLT 774

Query: 789 EVTGPPTELEPAQDSLVQSESYT--QNKALTAPEEHKAST 826
             T  PT   P +   + +E  T    +  T  EE   ST
Sbjct: 775 IPTEKPT--IPTEKPTIPTEKPTISTEEPTTPTEETTIST 812


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.127    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,156,188
Number of Sequences: 37866
Number of extensions: 4468609
Number of successful extensions: 26086
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 209
Number of HSP's successfully gapped in prelim test: 1192
Number of HSP's that attempted gapping in prelim test: 16180
Number of HSP's gapped (non-prelim): 6358
length of query: 1700
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1584
effective length of database: 13,855,062
effective search space: 21946418208
effective search space used: 21946418208
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.