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Search of human proteins with 165905613
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|165905613 ring finger and KH domain containing 1 [Homo
sapiens]
(651 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|165905613 ring finger and KH domain containing 1 [Homo sapiens] 1338 0.0
gi|47716512 mex-3 homolog B [Homo sapiens] 449 e-126
gi|148229134 ring finger and KH domain containing 2 [Homo sapiens] 432 e-121
gi|147902746 MEX3A protein [Homo sapiens] 383 e-106
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 71 3e-12
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 65 3e-10
gi|5453936 POU class 3 homeobox 3 [Homo sapiens] 64 3e-10
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 63 7e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni... 61 4e-09
gi|113421234 PREDICTED: similar to NG5 protein [Homo sapiens] 60 5e-09
gi|113420954 PREDICTED: similar to NG5 protein [Homo sapiens] 60 5e-09
gi|55741677 SET domain containing 1A [Homo sapiens] 60 5e-09
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 60 5e-09
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 60 6e-09
gi|210032580 SET domain containing 1B [Homo sapiens] 60 6e-09
gi|59806361 hypothetical protein LOC387104 [Homo sapiens] 60 8e-09
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re... 59 1e-08
gi|12751477 forkhead box L2 [Homo sapiens] 59 2e-08
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 58 2e-08
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 58 2e-08
gi|110832843 TBP-associated factor 4 [Homo sapiens] 58 2e-08
gi|239749482 PREDICTED: hypothetical protein [Homo sapiens] 58 3e-08
gi|239743620 PREDICTED: hypothetical protein [Homo sapiens] 58 3e-08
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 58 3e-08
gi|74027249 tripartite motif-containing 33 protein isoform alpha... 58 3e-08
gi|73476377 LBXCOR1 homolog [Homo sapiens] 58 3e-08
gi|39812378 RAN binding protein 9 [Homo sapiens] 57 5e-08
gi|55750053 atrophin-1 [Homo sapiens] 57 7e-08
gi|55750041 atrophin-1 [Homo sapiens] 57 7e-08
gi|154759423 Cdk5 and Abl enzyme substrate 1 isoform 2 [Homo sap... 56 9e-08
>gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]
Length = 651
Score = 1338 bits (3463), Expect = 0.0
Identities = 651/651 (100%), Positives = 651/651 (100%)
Query: 1 MPSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALR 60
MPSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALR
Sbjct: 1 MPSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALR 60
Query: 61 LALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVA 120
LALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVA
Sbjct: 61 LALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVA 120
Query: 121 PGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPPTLLADQMSVIGSRKKSVNMT 180
PGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPPTLLADQMSVIGSRKKSVNMT
Sbjct: 121 PGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPPTLLADQMSVIGSRKKSVNMT 180
Query: 181 ECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFIVTGRKEDVEMAKREI 240
ECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFIVTGRKEDVEMAKREI
Sbjct: 181 ECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFIVTGRKEDVEMAKREI 240
Query: 241 LSAAEHFSIIRATRSKAGGLPGAAQGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQ 300
LSAAEHFSIIRATRSKAGGLPGAAQGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQ
Sbjct: 241 LSAAEHFSIIRATRSKAGGLPGAAQGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQ 300
Query: 301 QRTHTYIVTPGRDKEPVFAVTGMPENVDRAREEIEAHITLRTGAFTDAGPDSDFHANGTD 360
QRTHTYIVTPGRDKEPVFAVTGMPENVDRAREEIEAHITLRTGAFTDAGPDSDFHANGTD
Sbjct: 301 QRTHTYIVTPGRDKEPVFAVTGMPENVDRAREEIEAHITLRTGAFTDAGPDSDFHANGTD 360
Query: 361 VCLDLLGAAASLWAKTPNQGRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDPGP 420
VCLDLLGAAASLWAKTPNQGRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDPGP
Sbjct: 361 VCLDLLGAAASLWAKTPNQGRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDPGP 420
Query: 421 ASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAA 480
ASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAA
Sbjct: 421 ASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAA 480
Query: 481 PLPAFSGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGA 540
PLPAFSGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGA
Sbjct: 481 PLPAFSGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGA 540
Query: 541 LSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAPALAREC 600
LSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAPALAREC
Sbjct: 541 LSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAPALAREC 600
Query: 601 VVCAEGEVMAALVPCGHNLFCMDCAVRICGKSEPECPACRTPATQAIHIFS 651
VVCAEGEVMAALVPCGHNLFCMDCAVRICGKSEPECPACRTPATQAIHIFS
Sbjct: 601 VVCAEGEVMAALVPCGHNLFCMDCAVRICGKSEPECPACRTPATQAIHIFS 651
>gi|47716512 mex-3 homolog B [Homo sapiens]
Length = 569
Score = 449 bits (1154), Expect = e-126
Identities = 281/556 (50%), Positives = 323/556 (58%), Gaps = 88/556 (15%)
Query: 162 LLADQMSVIG-------------SRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAK 208
L DQ+S++G RKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAK
Sbjct: 36 LALDQLSLLGLDSDEGASLYDSEPRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAK 95
Query: 209 TNTYIKTPVRGEEPVFIVTGRKEDVEMAKREILSAAEHFSIIRATRSKAGGLPGAAQGPP 268
TNTYIKTPVRGEEPVF+VTGRKEDV MA+REI+SAAEHFS+IRA+R+K L GA GPP
Sbjct: 96 TNTYIKTPVRGEEPVFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGAVPGPP 155
Query: 269 NLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIVTPGRDKEPVFAVTGMPENVD 328
NLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQ+THTYIVTP RDKEPVF VTGMPENVD
Sbjct: 156 NLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVD 215
Query: 329 RAREEIEAHITLRTGAFTDAGPDSDFHANGTDVCLDLL-----GAAASLWAK-----TPN 378
RAREEIEAHI LRTG + ++DFHANGTDV DL SLW+K TP
Sbjct: 216 RAREEIEAHIALRTGGIIELTDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPT 275
Query: 379 QGRRPPTATAGLRGD--TALGAPSAPEAFYAGSRGGPSVPD-------PGPASPYSGSGN 429
GR+P + R D ++LG+ S F G+ + P PA ++ +GN
Sbjct: 276 PGRKP---FSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGN 332
Query: 430 -----GGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERA----A 480
G+ + A G +PD C F P A IWA FER+
Sbjct: 333 NNNNGNGYTYTA---GGEASVPSPDGCP-ELQPTFDPAPAPPPGAPLIWAQFERSPGGGP 388
Query: 481 PLPAFSGCSTV--------------NGAPGPPAAG------ARRSSGAGTPRHSPTLPEP 520
P S CS+ GA P A R G PR SP L
Sbjct: 389 AAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHMA 448
Query: 521 GGLRLELPLSRRGAPDPVGALSWRPPQGPVSFPGGAAFST-ATSLPSSPAAAACAPLDSG 579
G E L+RR DP G GG A++ A L + +
Sbjct: 449 PGAG-EHHLARRVRSDPGG--------------GGLAYAAYANGLGAQLPGLQPSDTSGS 493
Query: 580 ASENSRKPPSASSAPAL----ARECVVCAEGEVMAALVPCGHNLFCMDCAVRICGKSEPE 635
+S +S S+SS+ L +R+C VC E EV+AALVPCGHNLFCM+CA RIC KSEPE
Sbjct: 494 SSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSEPE 553
Query: 636 CPACRTPATQAIHIFS 651
CP C T TQAI IFS
Sbjct: 554 CPVCHTAVTQAIRIFS 569
Score = 66.2 bits (160), Expect = 9e-11
Identities = 75/256 (29%), Positives = 99/256 (38%), Gaps = 51/256 (19%)
Query: 1 MPSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALR 60
MPSSL G GGGGGG GE D AL+
Sbjct: 1 MPSSLFADLERNGSGGGGGGSSGGGETL-------------------------DDQRALQ 35
Query: 61 LALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVA 120
LALDQLS LGL D+DE + D + E VP E A
Sbjct: 36 LALDQLSLLGL----DSDEGASLYDSEPRKKSVN---MTECVPVPSSEHVAEIVGRQGC- 87
Query: 121 PGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPPTLL--ADQMSVI-GSRKKSV 177
+ L + P R P A+ ++ A+ S+I SR K+
Sbjct: 88 --KIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNT 145
Query: 178 NMTECVPVPSS-------------EHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVF 224
+ VP P + V +VG +G IK ++ +T+TYI TP R +EPVF
Sbjct: 146 ALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVF 205
Query: 225 IVTGRKEDVEMAKREI 240
VTG E+V+ A+ EI
Sbjct: 206 EVTGMPENVDRAREEI 221
Score = 31.6 bits (70), Expect = 2.4
Identities = 40/136 (29%), Positives = 48/136 (35%), Gaps = 21/136 (15%)
Query: 9 DGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSA 68
+G G G A GE P P PE PAP PPP A L A + S
Sbjct: 330 NGNNNNNGNGYTYTAGGEASVPSPDGCPELQPTFDPAPAPPP-----GAPLIWAQFERSP 384
Query: 69 LGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLD 128
G G AA ++ + A A+ V G A AP + +L LL
Sbjct: 385 ----GGGP-----AAPVSSSCSSSASSSASSSSVVFPGGGASAP-------SNANLGLLV 428
Query: 129 PNASPPPPPPPRPSPP 144
P PR SPP
Sbjct: 429 HRRLHPGTSCPRLSPP 444
>gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]
Length = 659
Score = 432 bits (1112), Expect = e-121
Identities = 260/507 (51%), Positives = 298/507 (58%), Gaps = 57/507 (11%)
Query: 150 FAPHPAALGPPTLLADQMSVIGSRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKT 209
+ P L +Q +++ R+KSVN TECVPVPSSEHVAEIVGRQGCKIKALRAKT
Sbjct: 205 YGPGGCGAAAAALNGEQAALL--RRKSVNTTECVPVPSSEHVAEIVGRQGCKIKALRAKT 262
Query: 210 NTYIKTPVRGEEPVFIVTGRKEDVEMAKREILSAAEHFSIIRATRSKAGGLPGAAQGPPN 269
NTYIKTPVRGEEP+F+VTGRKEDV MAKREILSAAEHFS+IRA+R+K G G PN
Sbjct: 263 NTYIKTPVRGEEPIFVVTGRKEDVAMAKREILSAAEHFSMIRASRNKNGPALGGLSCSPN 322
Query: 270 LPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIVTPGRDKEPVFAVTGMPENVDR 329
LPGQTT+QVRVPYRVVGLVVGPKGATIKRIQQ+THTYIVTP RDKEPVF VTGMPENVDR
Sbjct: 323 LPGQTTVQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDR 382
Query: 330 AREEIEAHITLRTGAFTDAGPDSDFHANGTDVCLDLLGAAASLWAKTPNQGRRPPTATAG 389
AREEIE HI +RTG + + ++DFH NGTDV + G S W + +
Sbjct: 383 AREEIEMHIAMRTGNYIELNEENDFHYNGTDVSFE-GGTLGSAWLSSNPVPPSRARMISN 441
Query: 390 LRGDTALGAPSAPEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGPGAPVGTAAPD 449
R D++ S Y GS + D P SP+S G F FG P A D
Sbjct: 442 YRNDSSSSLGSGSTDSYFGSN---RLADFSPTSPFS---TGNFWFGDTLPSVGSEDLAVD 495
Query: 450 DCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRSSGAG 509
A D +A TIW PFE PL F P RR S
Sbjct: 496 S---------PAFDSLPTSAQTIWTPFEPVNPLSGF------GSDPSGNMKTQRRGSQPS 540
Query: 510 TPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQG-----PVSFPGGAAFSTATSL 564
TPR SPT PE +E PL+RR DP P G P+ P AFS T+
Sbjct: 541 TPRLSPTFPE----SIEHPLARRVRSDP-------PSTGNHVGLPIYIP---AFSNGTNS 586
Query: 565 PSSPAAAACAPLDSGASENSRKPPSASSAPALARECVVCAEGEVMAALVPCGHNLFCMDC 624
SS +G S +S P S +CV+C E EV+AALVPCGHNLFCM+C
Sbjct: 587 YSS---------SNGGSTSSSPPESRRK-----HDCVICFENEVIAALVPCGHNLFCMEC 632
Query: 625 AVRICGKSEPECPACRTPATQAIHIFS 651
A +IC K P CP C+T TQAI I S
Sbjct: 633 ANKICEKRTPSCPVCQTAVTQAIQIHS 659
Score = 58.9 bits (141), Expect = 1e-08
Identities = 79/316 (25%), Positives = 113/316 (35%), Gaps = 38/316 (12%)
Query: 23 AAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGA 82
AA P P P PPP P P PE + LR ++L+ALGL
Sbjct: 12 AAAPAPLPQPPPPPPPPPPPLPPPSGGPELEGDGLLLR---ERLAALGLDD--------- 59
Query: 83 AGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPS 142
P P P P AP A A + L P PP P P
Sbjct: 60 ----------------PSPAEPGAPALRAPAAAAQGQARRAAE-LSPEERAPPGRPGAPE 102
Query: 143 PPDVFA---GFAPHPAALGPPTLLADQMSVIGSRKKSVNMTECVPVPSSEHVAEIVGRQG 199
++ A L L +++ +S + P ++ +I G G
Sbjct: 103 AAELELEEDEEEGEEAELDGDLLEEEELEEAEEEDRSSLLLLSPPAATASQTQQIPG--G 160
Query: 200 CKIKALRAKTNTYIKTPVRGEEPVFIVTGRKEDVEMAKREILSAAEHFSIIRATRSKAGG 259
L + ++ G +D + +LS A A + G
Sbjct: 161 SLGSVLLPAARFDAREAAAAAAAAGVLYG-GDDAQGMMAAMLSHAYGPGGCGAAAAALNG 219
Query: 260 LPGAAQGPPNLPGQTTIQVRVP-YRVVGLVVGPKGATIKRIQQRTHTYIVTPGRDKEPVF 318
A ++ TT V VP V +VG +G IK ++ +T+TYI TP R +EP+F
Sbjct: 220 EQAALLRRKSV--NTTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPIF 277
Query: 319 AVTGMPENVDRAREEI 334
VTG E+V A+ EI
Sbjct: 278 VVTGRKEDVAMAKREI 293
Score = 45.4 bits (106), Expect = 2e-04
Identities = 76/310 (24%), Positives = 110/310 (35%), Gaps = 46/310 (14%)
Query: 109 AGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSPPDVFAGFA--------------PHP 154
+G+ LA A AP LP P PPPPP P PS G P P
Sbjct: 3 SGSSAALALAAAPAPLPQPPPPPPPPPPPLPPPSGGPELEGDGLLLRERLAALGLDDPSP 62
Query: 155 AALGPPTLLADQMSVIGSRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIK 214
A G P L A + G +++ ++ P GR G A A +
Sbjct: 63 AEPGAPALRAPAAAAQGQARRAAELSPEERAPP--------GRPG----APEAAELELEE 110
Query: 215 TPVRGEEPVFIVTG---RKEDVEMAKREILSAAEHFSIIRATRSKAGGLPGAAQGPPNLP 271
GEE + G +E++E A+ E S+ S AT S+ +PG + G LP
Sbjct: 111 DEEEGEEAE--LDGDLLEEEELEEAEEEDRSSLLLLSPPAATASQTQQIPGGSLGSVLLP 168
Query: 272 GQ--TTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIVTPGRDKEPVFAVTGMPENVDR 329
+ G++ G A +H Y PG A+ G + R
Sbjct: 169 AARFDAREAAAAAAAAGVLYGGDDAQGMMAAMLSHAY--GPGGCGAAAAALNGEQAALLR 226
Query: 330 AREEIEAHITLRTGAFTDAGPDSDFHAN--GTDVC-LDLLGAAASLWAKTPNQGRRPPTA 386
R+ + + P S+ A G C + L A + + KTP +G P
Sbjct: 227 -RKSVNTTECVPV-------PSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPIFV 278
Query: 387 TAGLRGDTAL 396
G + D A+
Sbjct: 279 VTGRKEDVAM 288
>gi|147902746 MEX3A protein [Homo sapiens]
Length = 520
Score = 383 bits (983), Expect = e-106
Identities = 263/606 (43%), Positives = 312/606 (51%), Gaps = 134/606 (22%)
Query: 58 ALRLALDQLSALGLGG--AGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTL 115
AL+LALDQL LGLG A E+G G G A A A A P+P PP PP
Sbjct: 37 ALQLALDQLCLLGLGEPPAPTAGEDGGGGGGGAPAQPA---APPQPAPP-------PPPA 86
Query: 116 APAVAPGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPPTLLADQMSVIGSRKK 175
AP AP + P A+ P PP P L A K
Sbjct: 87 APPAAPTAAP-----AAQTPQPPTAPK-------------GASDAKLCALYKEAELRLKG 128
Query: 176 SVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFIVTGRKEDVEM 235
S N TECVPVP+SEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVF+VTGR+EDV
Sbjct: 129 SSNTTECVPVPTSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFMVTGRREDVAT 188
Query: 236 AKREILSAAEHFSIIRATRSKAGGLPGAAQGPPNLPGQTTIQVRVPYRVVGLVVGPKGAT 295
A+REI+SAAEHFS+IRA+R+K+G G A P LPGQ TI+VRVPYRVVGLVVGPKGAT
Sbjct: 189 ARREIISAAEHFSMIRASRNKSGAAFGVA---PALPGQVTIRVRVPYRVVGLVVGPKGAT 245
Query: 296 IKRIQQRTHTYIVTPGRDKEPVFAVTGMPENVDRAREEIEAHITLRTGAFTDAGPDSDFH 355
IKRIQQ+T+TYI+TP RD++PVF +TG P NV+RAREEIE HI +RTG + ++DF
Sbjct: 246 IKRIQQQTNTYIITPSRDRDPVFEITGAPGNVERAREEIETHIAVRTGKILEYNNENDFL 305
Query: 356 ANGTDVCLDLLGAAASLWAKTPNQGRRPPTA----TAGLRGDTALGAPSAPEAFYAGSRG 411
A D +D + W + G +P + + G G+ G S EA G +G
Sbjct: 306 AGSPDAAID--SRYSDAW-RVHQPGCKPLSTFRQNSLGCIGE--CGVDSGFEAPRLGEQG 360
Query: 412 GPSVPDPGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAAT 471
G G GG+ F PG VG D +G +
Sbjct: 361 G-------------DFGYGGYLF----PGYGVG---KQDVYYG----------VAETSPP 390
Query: 472 IWAPFERAAPLPAF------SGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRL 525
+WA E A P S S+ GPP A ++ AG PE G
Sbjct: 391 LWAGQENATPTSVLFSSASSSSSSSAKARAGPPGAHRSPATSAG--------PELAG--- 439
Query: 526 ELPLSRRGAPDPVGALSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSR 585
L RR +P+ QG GG S
Sbjct: 440 ---LPRRPPGEPL--------QGFSKLGGGGLRS-------------------------- 462
Query: 586 KPPSASSAPALARECVVCAEGEVMAALVPCGHNLFCMDCAVRICGKSEPECPACRTPATQ 645
P R+C+VC E EV AALVPCGHNLFCM+CAVRIC +++PECP C ATQ
Sbjct: 463 --------PGGGRDCMVCFESEVTAALVPCGHNLFCMECAVRICERTDPECPVCHITATQ 514
Query: 646 AIHIFS 651
AI IFS
Sbjct: 515 AIRIFS 520
Score = 50.8 bits (120), Expect = 4e-06
Identities = 35/80 (43%), Positives = 41/80 (51%), Gaps = 9/80 (11%)
Query: 8 PDGGGGGGGGGGGVGAAGEDPGPGPAPP-----PEGAQEAAPA---PRPPPEPDDAAAAL 59
P G GGGGGGG A P P PAPP P A AAPA P+PP P A+ A
Sbjct: 56 PTAGEDGGGGGGGAPAQPAAP-PQPAPPPPPAAPPAAPTAAPAAQTPQPPTAPKGASDAK 114
Query: 60 RLALDQLSALGLGGAGDTDE 79
AL + + L L G+ +T E
Sbjct: 115 LCALYKEAELRLKGSSNTTE 134
Score = 31.2 bits (69), Expect = 3.1
Identities = 35/137 (25%), Positives = 47/137 (34%), Gaps = 23/137 (16%)
Query: 477 ERAAPLPAFSGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPD 536
ERA L C G P P AG G G P P + AP
Sbjct: 35 ERALQLALDQLCLLGLGEPPAPTAGEDGGGGGGGAPAQPAAPP------------QPAPP 82
Query: 537 PVGALSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAPAL 596
P PP P + P A + P++P A+ A L + E + +S+
Sbjct: 83 P-------PPAAPPAAPTAAPAAQTPQPPTAPKGASDAKLCALYKEAELRLKGSSN---- 131
Query: 597 ARECVVCAEGEVMAALV 613
ECV E +A +V
Sbjct: 132 TTECVPVPTSEHVAEIV 148
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 71.2 bits (173), Expect = 3e-12
Identities = 177/642 (27%), Positives = 209/642 (32%), Gaps = 112/642 (17%)
Query: 1 MPSSLGQPDGGGGGG--GGGGGVGAAGEDPGP-GPAPPP--EGAQEAAPAPRPPPEPDDA 55
+P G+P G G G G GAAG PGP GPA PP GA A P P +
Sbjct: 306 LPGERGRPGAPGPAGARGNDGATGAAGP-PGPTGPAGPPGFPGAV-GAKGEAGPQGPRGS 363
Query: 56 AAALRLALDQLSALGLGGAGDTDEEGAAGD-GAAAAGGADGGAAPEPVP----PDGPEA- 109
+ + G AG GA G GA A GA G A P P GP+
Sbjct: 364 EGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGP 423
Query: 110 GAPP----TLAPAVAPGSLPLLDPNASPPP-----PPPPRPSPPDVFAGFAPHPAAL-GP 159
G PP APGS P P PP P A P P L GP
Sbjct: 424 GGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGP 483
Query: 160 PTLLADQMSVIGSRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRG 219
P + GSR P ++ VA G G RG
Sbjct: 484 P----GERGGPGSRG----------FPGADGVAGPKGPAG-----------------ERG 512
Query: 220 EEPVFIVTGRKEDVEMAKREILSAAEHFSIIRATRSKAG--GLPGAA-----QGPPNLPG 272
G + L A+ + + G G PG A GPP PG
Sbjct: 513 SPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPG 572
Query: 273 QTTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIVTPGRDKEPVFAVTGMPENVDRARE 332
R V+G GPKGA + PG+ E V G P V A +
Sbjct: 573 -----ARGQAGVMGFP-GPKGAAGE------------PGKAGER--GVPGPPGAVGPAGK 612
Query: 333 EIEAHITLRTGAFTDAGPDSDFHANGTDVCLDLLGAAASLWAKTPNQGRRPPTATAGLRG 392
+ EA G AG + G+ L G A P + +P G+ G
Sbjct: 613 DGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGP-----PGEAGKP--GEQGVPG 665
Query: 393 DTALGAPSAP--EAFYAGSRGGPSVPDP-GPASPYSGSGNGGFAFGAEGPGAPVGTAAPD 449
D PS E + G RG P P GP GN G A PGAP AP
Sbjct: 666 DLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPG 725
Query: 450 DCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPA-AGARRSSGA 508
G + A L P A + A P G + G GPP AGA G
Sbjct: 726 --LQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGE 783
Query: 509 GTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGPVSFPG-----GAAFSTATS 563
P P G R P RG P P G + P G PG G A + +
Sbjct: 784 SGPSGP---AGPTGAR-GAP-GDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDA 838
Query: 564 LPSSPAAAACAPLDSG--------ASENSRKPPSASSAPALA 597
P PA A P G + S PP A+ P A
Sbjct: 839 GPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAA 880
Score = 53.1 bits (126), Expect = 8e-07
Identities = 71/229 (31%), Positives = 86/229 (37%), Gaps = 41/229 (17%)
Query: 389 GLRGDTALGAPSAPEAFYA-------GSRGGPSVPDP----GPASPYSGSGNGGFAFGAE 437
G +GD GAP AP + A G RG +P P G A P G+ G G
Sbjct: 707 GAKGDA--GAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPG-KDGVR 763
Query: 438 GPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAAT--IWAPFERAAPLP----AFSGCSTV 491
G P+G P G D + PA T AP +R P P F+G
Sbjct: 764 GLTGPIGPPGPA----GAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGA 819
Query: 492 NGAPG----PPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQ 547
+G PG P AGA+ +G P P P PG P+ GAP GA P
Sbjct: 820 DGQPGAKGEPGDAGAKGDAGPPGPA-GPAGP-PG------PIGNVGAPGAKGARGSAGPP 871
Query: 548 GPVSFPGGAAFSTATSLPSSPAAAACAPLDSG-ASENSRKPPSASSAPA 595
G FPG A P P+ A P G A + K P + PA
Sbjct: 872 GATGFPGAA----GRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPA 916
Score = 50.1 bits (118), Expect = 7e-06
Identities = 52/172 (30%), Positives = 61/172 (35%), Gaps = 20/172 (11%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPP-------EGAQEAAPAPRPPPEPDD 54
P P G G G G GA+G GP PP E + P R PP P
Sbjct: 192 PPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQG 251
Query: 55 A-----AAALRLALDQLSALGLGGA-GDTDEEGAAGD-GAAAAGGADGGAAPEPVPPDGP 107
A A L GL GA GD G G+ G+ GA G P +P +
Sbjct: 252 ARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERG 311
Query: 108 EAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGP 159
GAP PA A G+ + PP P P+ P F G GP
Sbjct: 312 RPGAP---GPAGARGN---DGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGP 357
Score = 48.5 bits (114), Expect = 2e-05
Identities = 91/332 (27%), Positives = 106/332 (31%), Gaps = 52/332 (15%)
Query: 259 GLPG-----AAQGPPNLPGQTTIQVRVPY---RVVGLVV-------GPKGATIKRIQQRT 303
GLPG GPP L G Q+ Y G+ V GP+G
Sbjct: 139 GLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGP 198
Query: 304 HTYIVTPGRDKEP----VFAVTGMPENVDRAREEIEAHITLRTGAFTDAGPDSDFHANGT 359
+ PG EP G P + ++ EA R G GP GT
Sbjct: 199 QGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGT 258
Query: 360 DVCLDLLG--AAASLWAKTPNQGRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPD 417
+ G + L + G P G G+ P G RG P P
Sbjct: 259 AGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGL-PGERGRPGAPG 317
Query: 418 PGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFE 477
P A GN G A GA GP P G A P GF P A + A E
Sbjct: 318 PAGA-----RGNDG-ATGAAGPPGPTGPAGPP----GF-----------PGA--VGAKGE 354
Query: 478 RAAPLPAFS-GCSTVNGAPGPPAAGARRSSGAGTPRHSPTLP-EPGGLRLELPLSRRGAP 535
P S G V G PGPP +GA P +P +PG GAP
Sbjct: 355 AGPQGPRGSEGPQGVRGEPGPPG-----PAGAAGPAGNPGADGQPGAKGANGAPGIAGAP 409
Query: 536 DPVGALSWRPPQGPVSFPGGAAFSTATSLPSS 567
GA PQGP PG S P S
Sbjct: 410 GFPGARGPSGPQGPGGPPGPKGNSGEPGAPGS 441
Score = 47.8 bits (112), Expect = 3e-05
Identities = 52/177 (29%), Positives = 60/177 (33%), Gaps = 25/177 (14%)
Query: 8 PDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLS 67
P G G G G G G PGPA P E+ P+ P A R
Sbjct: 750 PKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPG 809
Query: 68 ALGLGGAGDTD-EEGAAGDGAAAAGGADGGAAPEPVPPDGPEA-----------GAPPTL 115
G G D + GA G+ A D G P P P GP GA +
Sbjct: 810 PAGFAGPPGADGQPGAKGEPGDAGAKGDAG-PPGPAGPAGPPGPIGNVGAPGAKGARGSA 868
Query: 116 APAVA---PGSLPLLDP-----NASPPPPPPPRPSP----PDVFAGFAPHPAALGPP 160
P A PG+ + P NA PP PP P P G A P +GPP
Sbjct: 869 GPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPP 925
Score = 47.4 bits (111), Expect = 4e-05
Identities = 62/200 (31%), Positives = 71/200 (35%), Gaps = 43/200 (21%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGED-----PGP-GPAPPP--------EGAQEAAPAPR 47
P+ P G G G G G AG PGP GPA PP GA+ A +
Sbjct: 810 PAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAG 869
Query: 48 PPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAG-DGAAAAGGADGGAA-PEPVPPD 105
PP AA R+ S G AG G AG +G G G A P V P
Sbjct: 870 PPGATGFPGAAGRVGPPGPS----GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPP 925
Query: 106 GP-----EAGAPPTLAPAVAPGS--------------LPLLDPNASPPPPPPPRPSP--- 143
GP E G+P PA APG+ LP P P P P
Sbjct: 926 GPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQ 985
Query: 144 -PDVFAGFAPHPAALGPPTL 162
P +G P +GPP L
Sbjct: 986 GPSGASGERGPPGPMGPPGL 1005
Score = 44.3 bits (103), Expect = 4e-04
Identities = 63/234 (26%), Positives = 72/234 (30%), Gaps = 56/234 (23%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGEDPGPG---------PAPPPEGAQEAAPAPRPP--- 49
P L P G G G G G+ G D PG PA PP GA A AP P
Sbjct: 1002 PPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPP-GAPGAPGAPGPVGPA 1060
Query: 50 ----PEPDDAAAALRLALDQLSALGLGGA----GDTDEEGAAGD-------------GAA 88
+ A + + A G G GD E G GD G
Sbjct: 1061 GKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPP 1120
Query: 89 AAGGADGGAAPE----PVPPDGPEA-----------GAPPTLAPAVAPGSLPLLDPNASP 133
G+ G P P P GP G P + P G P P
Sbjct: 1121 GPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPP 1180
Query: 134 PPPPPPRPSPPDVFA---GFAPHP----AALGPPTLLADQMSVIGSRKKSVNMT 180
PP PP P P F P P A G AD +V+ R V+ T
Sbjct: 1181 GPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTT 1234
Score = 43.1 bits (100), Expect = 8e-04
Identities = 45/154 (29%), Positives = 51/154 (33%), Gaps = 26/154 (16%)
Query: 8 PDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLS 67
P G G G G G G+ PGP PP P PP + A L D+ S
Sbjct: 119 PRGPRGPAGPPGRDGIPGQPGLPGPPGPPG-------PPGPPGLGGNFAPQLSYGYDEKS 171
Query: 68 ALGLGGAGDTDEEGAAG-DGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPL 126
G+ G G G G A G G P P P P A P
Sbjct: 172 TGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGP-PGEPGEPGASGP-------------- 216
Query: 127 LDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPP 160
+ P PP PP + D AG P GPP
Sbjct: 217 MGPRG---PPGPPGKNGDDGEAGKPGRPGERGPP 247
Score = 41.6 bits (96), Expect = 0.002
Identities = 56/205 (27%), Positives = 65/205 (31%), Gaps = 50/205 (24%)
Query: 389 GLRGDTALGAPSAPEAFYAGSRGGPSVPDP-GPASPYSGSGNGGFAFGAEGPGAPVGTAA 447
G +GD P+ P G+ G P P P GPA G G A G GP PVG
Sbjct: 1031 GAKGDRGETGPAGPP----GAPGAPGAPGPVGPAGKSGDRGETGPA-GPAGPVGPVGARG 1085
Query: 448 P--------DDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPA 499
P D + G D + G S + G PGPP
Sbjct: 1086 PAGPQGPRGDKGETGEQGD---------------------RGIKGHRGFSGLQGPPGPPG 1124
Query: 500 A----GARRSSGAGTPRHSPTLPE----------PGGLRLELPLSRRGAPDPVGALSWRP 545
+ G +SG PR P PG + P R G PVG
Sbjct: 1125 SPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPG 1184
Query: 546 PQGPVSFP-GGAAFSTATSLPSSPA 569
P GP P G FS P A
Sbjct: 1185 PPGPPGPPSAGFDFSFLPQPPQEKA 1209
Score = 40.0 bits (92), Expect = 0.007
Identities = 30/89 (33%), Positives = 37/89 (41%), Gaps = 11/89 (12%)
Query: 379 QGRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPS------VPDP-GPASPYSGSGNGG 431
QG P + G +G + P+ P GS G P +P P GP P +G+ G
Sbjct: 1117 QGPPGPPGSPGEQGPSGASGPAGPRG-PPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAG 1175
Query: 432 FAFGAEGPGAPVGTAAPDDCDFGFDFDFL 460
G GP P G P GFDF FL
Sbjct: 1176 -PVGPPGPPGPPGPPGPPSA--GFDFSFL 1201
Score = 39.7 bits (91), Expect = 0.009
Identities = 62/239 (25%), Positives = 72/239 (30%), Gaps = 59/239 (24%)
Query: 380 GRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGP 439
G P AG RG +G P G RG P +P P G G GP
Sbjct: 947 GTPGPQGIAGQRG--VVGLPGQ-----RGERGFPGLPGPSGEPGKQGPSGASGERGPPGP 999
Query: 440 GAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAP-LPAFSGCSTVNGAPGPP 498
P G A P P E P G +G+PG
Sbjct: 1000 MGPPGLAGP--------------------------PGESGREGAPGAEGSPGRDGSPG-- 1031
Query: 499 AAGARRSSGAGTPRHSPTLP-EPG--------GLRLEL-PLSRRGAPDPVGALSWRPPQG 548
A G R +G P +P P PG G R E P G PVGA PQG
Sbjct: 1032 AKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQG 1091
Query: 549 P------------VSFPGGAAFSTATSLPSSPAA-AACAPLDSGASENSRKPPSASSAP 594
P G FS P P + P + R PP ++ AP
Sbjct: 1092 PRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAP 1150
Score = 38.1 bits (87), Expect = 0.026
Identities = 70/285 (24%), Positives = 80/285 (28%), Gaps = 62/285 (21%)
Query: 343 GAFTDAGPDSDFHANGTDVCLDLLGAAASLWAKTPNQGRRPPTATA--------GLRGDT 394
GA DAGP G + +GA AK PP AT G G +
Sbjct: 833 GAKGDAGPPGPAGPAGPPGPIGNVGAPG---AKGARGSAGPPGATGFPGAAGRVGPPGPS 889
Query: 395 ALGAPSAPEAFYAGSRGGPS-------------VPDPGPASPYSGSGNGGFAFGAEGPGA 441
P P AG GG V PGP P G+ GA+GP
Sbjct: 890 GNAGPPGPPG-PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSP----GADGPAG 944
Query: 442 PVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERA-APLPAFSGCSTVNGAPGPPAA 500
GT P + P +R P G S G GP A
Sbjct: 945 APGTPGPQG--------------IAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGA 990
Query: 501 GARRSSGAGTPRHSPTLPEP-------GGLRLELPLSRRGAPDPVGALSWRPPQGPVSFP 553
R G P P L P G E R G+P G P GP P
Sbjct: 991 SGER--GPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP 1048
Query: 554 GGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAPALAR 598
G P +P A E P+ P AR
Sbjct: 1049 GA---------PGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGAR 1084
Score = 38.1 bits (87), Expect = 0.026
Identities = 46/167 (27%), Positives = 53/167 (31%), Gaps = 22/167 (13%)
Query: 8 PDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLS 67
P G GG G G G AG GP PP A E P + Q
Sbjct: 900 PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRG 959
Query: 68 ALGL-GGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPD--GPE--AGAPPTLAPAVAPG 122
+GL G G+ G G GA+ E PP GP AG P APG
Sbjct: 960 VVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPG 1019
Query: 123 SLPLLDPNASP----------PPPPPPRPSPPDVFAGFAPHPAALGP 159
+ + SP P PP P P P +GP
Sbjct: 1020 AEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGA-------PGPVGP 1059
Score = 35.8 bits (81), Expect = 0.13
Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 1/51 (1%)
Query: 1 MPSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPE 51
+P +G P G G G G VG G PGP PP + + P+PP E
Sbjct: 1158 LPGPIGPP-GPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQE 1207
Score = 32.0 bits (71), Expect = 1.8
Identities = 33/107 (30%), Positives = 36/107 (33%), Gaps = 21/107 (19%)
Query: 72 GGAGDTDEEGAAGDGAAAAGGADG--GAAPEPVPPDGPEAGAPPTL----APAVA----- 120
G GDT G G A G DG G P PP P PP L AP ++
Sbjct: 112 GPKGDTGPRGPRGP--AGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDE 169
Query: 121 --------PGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGP 159
PG + P P PP P P G P A GP
Sbjct: 170 KSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGP 216
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 64.7 bits (156), Expect = 3e-10
Identities = 52/143 (36%), Positives = 59/143 (41%), Gaps = 17/143 (11%)
Query: 32 PAPP--PEGAQEAA--------PAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEG 81
PAPP P GA AA PAP PPP P AAA R +A + + G
Sbjct: 109 PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPG 168
Query: 82 AAGDGAA--AAGGADGGAAPEPVPPDGPEAGAPPTLA---PAVAPGSLPLLDPNASPPPP 136
AA AA A P PP GP PP +A P + P P P PPP
Sbjct: 169 PRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPP 228
Query: 137 PPPRPSPPD--VFAGFAPHPAAL 157
P P+P P V AG A P +L
Sbjct: 229 PQPQPPPEGGAVRAGGAARPVSL 251
Score = 40.4 bits (93), Expect = 0.005
Identities = 37/123 (30%), Positives = 44/123 (35%), Gaps = 24/123 (19%)
Query: 47 RPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDG 106
R PEP+ A L + Q + L + G AA G A P PP
Sbjct: 61 RHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRG------ATPPAPPRA 114
Query: 107 PEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPP----------RPSPPDVFAGFAPHPAA 156
P GAP A A P P +PPPPP P R + A +P PA
Sbjct: 115 PR-GAPAAAAAAAPP-------PTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQ 166
Query: 157 LGP 159
GP
Sbjct: 167 PGP 169
Score = 39.3 bits (90), Expect = 0.011
Identities = 52/184 (28%), Positives = 61/184 (33%), Gaps = 42/184 (22%)
Query: 377 PNQGRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGA 436
P +G PP RG A A +AP P P P P
Sbjct: 102 PRRGATPPAPPRAPRGAPAAAAAAAP----------PPTPAPPP---------------- 135
Query: 437 EGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAP---FERAAPLPAFSGCSTVNG 493
P APV AAP A T P + P +RAAPL A
Sbjct: 136 --PPAPVAAAAPARAPRA-----AAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPP 188
Query: 494 APGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGPVSFP 553
A PP AG RR+ P LP P + P ++ P P PP+G
Sbjct: 189 AVAPP-AGPRRAPPPAVAAREPPLPPPP--QPPAPPQQQQPPPP---QPQPPPEGGAVRA 242
Query: 554 GGAA 557
GGAA
Sbjct: 243 GGAA 246
Score = 37.4 bits (85), Expect = 0.044
Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 17/105 (16%)
Query: 503 RRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGPVSFPGGAAFSTAT 562
R ++ PR T P P P + RGAP A + P P P A +
Sbjct: 94 RNAARVQPPRRGATPPAP-------PRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPA 146
Query: 563 SLPSSPAAAACAPLDSG----------ASENSRKPPSASSAPALA 597
P + AAAA AP G A+ + PP+ ++ PA+A
Sbjct: 147 RAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVA 191
Score = 36.2 bits (82), Expect = 0.097
Identities = 37/135 (27%), Positives = 47/135 (34%), Gaps = 17/135 (12%)
Query: 467 PAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRLE 526
PAAA AP AP P + A PA R ++ A T SP +PG
Sbjct: 119 PAAAAAAAPPPTPAPPPPPAPV-----AAAAPARAPRAAAAAATAPPSPGPAQPG----- 168
Query: 527 LPLSRRGAP------DPVGALSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGA 580
P ++R AP P + PP GP P A + LP P A
Sbjct: 169 -PRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPP 227
Query: 581 SENSRKPPSASSAPA 595
+ PP + A
Sbjct: 228 PPQPQPPPEGGAVRA 242
Score = 34.7 bits (78), Expect = 0.28
Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 5/101 (4%)
Query: 495 PGPPAA--GARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGPVSF 552
P PP A GA ++ A P +P P P +R AP A + PP +
Sbjct: 109 PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPAR--APRAAAAAATAPPSPGPAQ 166
Query: 553 PGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSA 593
PG A A L + P A A P + + R PP A +A
Sbjct: 167 PGPRA-QRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAA 206
>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
Length = 500
Score = 64.3 bits (155), Expect = 3e-10
Identities = 52/182 (28%), Positives = 64/182 (35%), Gaps = 17/182 (9%)
Query: 10 GGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALR--------- 60
GGGGGGGGGGG G G PG A GA P+ + D A+
Sbjct: 33 GGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNGGHMLS 92
Query: 61 ------LALDQLSALGLGGAGDTDEEGAAGDGAAA--AGGADGGAAPEPVPPDGPEAGAP 112
AL +A A E + G+A AG P P PP GP+
Sbjct: 93 HAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGG 152
Query: 113 PTLAPAVAPGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPPTLLADQMSVIGS 172
A +L P PPPPPP P + A AA A S+ G
Sbjct: 153 AGRDDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGG 212
Query: 173 RK 174
++
Sbjct: 213 QQ 214
Score = 34.3 bits (77), Expect = 0.37
Identities = 37/124 (29%), Positives = 44/124 (35%), Gaps = 12/124 (9%)
Query: 18 GGGVGAAG--EDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAG 75
G VG AG + P P PPP+G A R DD A AL LG
Sbjct: 124 GSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGR-----DDLHAGT--ALHHRGPPHLGPPP 176
Query: 76 DTDEEGAAGD---GAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNAS 132
+G G AAAA A AA +P PP PG + ++
Sbjct: 177 PPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSA 236
Query: 133 PPPP 136
PP P
Sbjct: 237 PPGP 240
Score = 32.3 bits (72), Expect = 1.4
Identities = 57/225 (25%), Positives = 77/225 (34%), Gaps = 40/225 (17%)
Query: 390 LRGDTALGAPSAPEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGPGAPVGTAAPD 449
L G++ L A S + AG+ GG G G GG G G G G+AA
Sbjct: 10 LPGNSLLAAGSIVHSDAAGAGGGGG----------GGGGGGGGGAGGGGGGMQPGSAAVT 59
Query: 450 DCDFGFD--------FDFLALDLTVPAAATIWA-PFERAAPLPAFSGCSTVNGAPGPPAA 500
+ D DF+ + + + + LP + + A A+
Sbjct: 60 SGAYRGDPSSVKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEAS 119
Query: 501 GARRSSG---AGTPRHSPTLPEP--------GG-----LRLELPLSRRGAPDPVGALSWR 544
S AG+P+ P P P GG L L RG P L
Sbjct: 120 SPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRGPPH----LGPP 175
Query: 545 PPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPS 589
PP PGG + A + ++ AAAA A L S A P S
Sbjct: 176 PPPPHQGHPGGWG-AAAAAAAAAAAAAAAAHLPSMAGGQQPPPQS 219
Score = 30.8 bits (68), Expect = 4.1
Identities = 16/36 (44%), Positives = 18/36 (50%)
Query: 5 LGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQ 40
L P G GGGGGG GG + PG PE A+
Sbjct: 234 LSAPPGPGGGGGGAGGGAQSLVHPGLVRGDTPELAE 269
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 63.2 bits (152), Expect = 7e-10
Identities = 56/187 (29%), Positives = 67/187 (35%), Gaps = 53/187 (28%)
Query: 10 GGGGGG----GGGGGVGAAGE-----------------DPGPG--------PAPPPEGAQ 40
GGGGGG GGGGG G + PGPG P PPP Q
Sbjct: 10 GGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQ 69
Query: 41 EAAPAPRPP------------PEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAGDGAA 88
+ P +PP P+P D + G G G+A ++
Sbjct: 70 QQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASS 129
Query: 89 AA-------GGADGGAAPEPVPPDGPE-AGAPPTLAPAVAPGS-LPLLDPNASPPPPPP- 138
+A GA G+ P P P P APP P P S +P P A PPPPP
Sbjct: 130 SAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPA 189
Query: 139 --PRPSP 143
P P P
Sbjct: 190 AVPGPGP 196
Score = 36.6 bits (83), Expect = 0.075
Identities = 30/113 (26%), Positives = 42/113 (37%), Gaps = 13/113 (11%)
Query: 495 PGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPP-------- 546
PGP +G + P P P + P + P P +PP
Sbjct: 49 PGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSK 108
Query: 547 ----QGPVSFPG-GAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAP 594
QGP PG G+A ++S P + + AP SG PP+ +SAP
Sbjct: 109 PVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAP 161
Score = 36.6 bits (83), Expect = 0.075
Identities = 48/165 (29%), Positives = 55/165 (33%), Gaps = 43/165 (26%)
Query: 418 PGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFE 477
PGPA G G+ A + P P + AP G P A AP
Sbjct: 115 PGPAP---GVGSAPPASSSAPPATPPTSGAPPGSGPG--------PTPTPPPAVTSAPPG 163
Query: 478 RAAPLPAFSGCSTV----NGAPGPPAA------GARRSSGAGTPRHS-----------PT 516
P P SG T G P PPAA G ++ G G P+ P
Sbjct: 164 APPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPG 223
Query: 517 LPEPGGLRLELPLSRRGAPDPVGALSWRPP------QGPVSFPGG 555
L PGG RG +P G PP QGP PGG
Sbjct: 224 LSTPGG---HPKPPHRGGGEPRGGRQHHPPYHQQHHQGPP--PGG 263
Score = 35.0 bits (79), Expect = 0.22
Identities = 35/127 (27%), Positives = 40/127 (31%), Gaps = 10/127 (7%)
Query: 14 GGGGGGGVGAAGEDPGPGP-APPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLG 72
G G GVG+A P A PP P P P P A + + G
Sbjct: 114 GPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSG 173
Query: 73 GAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPP--TLAPAVAPGSLP-LLDP 129
+ G AA G P P P GP G P + PG P L P
Sbjct: 174 VPTTPPQAGGPPPPPAAVPG------PGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTP 227
Query: 130 NASPPPP 136
P PP
Sbjct: 228 GGHPKPP 234
Score = 29.6 bits (65), Expect = 9.1
Identities = 24/71 (33%), Positives = 27/71 (38%), Gaps = 7/71 (9%)
Query: 383 PPTATAGLRGDTALGAPSAPEAFYAGSRGGPS-----VPDPGPASPYSGSGNGGFAFGAE 437
PP T+ G PS+ GGP VP PGP P G G GG G +
Sbjct: 154 PPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGP-GPKQGPGPGG-PKGGK 211
Query: 438 GPGAPVGTAAP 448
PG P P
Sbjct: 212 MPGGPKPGGGP 222
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 60.8 bits (146), Expect = 4e-09
Identities = 66/243 (27%), Positives = 89/243 (36%), Gaps = 48/243 (19%)
Query: 373 WAKTPNQGRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDPG---------PASP 423
WA TP PP+ G + GAP+ P A +GGP+ P P P SP
Sbjct: 961 WAPTP-PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSP 1019
Query: 424 YSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATI--WAPFERAAP 481
F GA P A + PAA + AP AA
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGS----------------PAATPLPKGAPTTPAAT 1063
Query: 482 LPAFSG---CSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPV 538
LP+ G ++ GAP PPAA +P+ P P P G + + P P
Sbjct: 1064 LPSPKGGPATPSLKGAPTPPAATPP------SPKGGPATPSPKGAPMPPAAT---PPSPK 1114
Query: 539 GALSWRPPQG--------PVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSA 590
G L+ P +G P S GG A P++PAA +P A+ + P+
Sbjct: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT 1174
Query: 591 SSA 593
+A
Sbjct: 1175 PAA 1177
Score = 59.7 bits (143), Expect = 8e-09
Identities = 66/229 (28%), Positives = 84/229 (36%), Gaps = 11/229 (4%)
Query: 369 AASLWAKTPNQGRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPD----PGPASPY 424
A S+ + +P + R P + GAP+ P A +GGP+ P P P +
Sbjct: 910 ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT 969
Query: 425 SGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPA 484
S GG A + GAP AA G P A T +P A P
Sbjct: 970 PPSPKGGPATPSP-KGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF 1028
Query: 485 FSGCSTVNGA--PGPPAAGARRSSGAGTP-RHSPTLPEPGGLRLELPLSRRGAPDPVGAL 541
G ST A P P + A G P + TLP P G S +GAP P A
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG--GPATPSLKGAPTPPAAT 1086
Query: 542 SWRPPQGPVS-FPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPS 589
P GP + P GA A + PS A P + + PPS
Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS 1135
Score = 56.2 bits (134), Expect = 9e-08
Identities = 68/229 (29%), Positives = 89/229 (38%), Gaps = 27/229 (11%)
Query: 383 PPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDP--GPASPYS--GSGNGGFAFGAEG 438
PP+ GL GAP+ P A +GG + P P P +P + S GG A +
Sbjct: 1133 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSP- 1191
Query: 439 PGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSG---CSTVNGAP 495
GAP AA G L P+ AP AA P+ G + GAP
Sbjct: 1192 KGAPTTPAATPPSPKG--------GLATPSPK--GAPTTPAATPPSPKGGLATPSPKGAP 1241
Query: 496 GPPAAGARRSSGAGT---PRHSPTLP--EPGGLR--LELPLSRRGAPDPVGALSWRPPQG 548
PAA G P+ +PT P P L+ L P +GAP+P P G
Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP-PHKGAPNPAVVTPPSPKGG 1300
Query: 549 PVSFPGGAAFSTATSLPSSPAAAACAPLDSGA-SENSRKPPSASSAPAL 596
P + P A + + P SP + P GA + + PPS P L
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL 1349
Score = 55.8 bits (133), Expect = 1e-07
Identities = 142/604 (23%), Positives = 201/604 (33%), Gaps = 108/604 (17%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRL 61
PSS G P G GP PP A P+P+ P + A + L
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP---TSPAVIPL 1410
Query: 62 ALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAP 121
+ + A + G AA + G P V P + AP T AP P
Sbjct: 1411 SPKKAPATPVTREG-------------AATPSKGDLTPPAVTPVSLKK-APATSAPKGGP 1456
Query: 122 GSL-----PLLDPNASPPPPPPPRPSPPDVFAGFAPH-----PAALGPPTLLADQMSVIG 171
+ P L P +PP P P P+P V +P PA +G PTL A VI
Sbjct: 1457 ATPSSKGDPTL-PAVTPPSPKEP-PAPKQVATSSSPKKAPATPAPMGAPTLPA----VIP 1510
Query: 172 SRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFIVTGRKE 231
S K V T PSS + P+ P + +K
Sbjct: 1511 SSPKEVPAT-----PSSR------------------------RDPI---APTATLLSKKT 1538
Query: 232 DVEMAKREILSAAEHFSIIRATRSKAGGLPGAAQGPPNLPGQTTIQVRVPYRVVG----- 286
+A +E L ++ ++ A P A P+ ++ P G
Sbjct: 1539 PATLAPKEAL-IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK 1597
Query: 287 -LVVGPKGATIKRIQQRTHTYIVTPGRDKEPVF-AVTGMPENVDRAREEIE------AHI 338
L++ P + + T + P +K P A G P + ++ A +
Sbjct: 1598 ELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASV 1657
Query: 339 TLRTGAFTDAGPDSDFHANGTDVCLDLLGAAA--SLWAKTPNQGRRPPTATAGLRGDTAL 396
T + GA G ++L A A S T + P T +
Sbjct: 1658 TCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPIC 1717
Query: 397 GAPSAPEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFD 456
PSA GS+G S P P P + A G + +P G AP +
Sbjct: 1718 PDPSAKN----GSKGPLSTVAPAPLLPVQ-KDSSKTAKGKDASHSPKGPLAPPES----- 1767
Query: 457 FDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRSSGAGT-PRHSP 515
+ P A A FE+ P P ++V+ AP PP + S T P
Sbjct: 1768 ------KASTPLTA---AAFEKVLPKPE---SASVSAAPSPPVSLPLAPSPVPTLPPKQQ 1815
Query: 516 TLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGPVSFPGGAAF-STATSLPSSPAAAACA 574
LP GL LE P D L PP+ P+S GG F S ++P+ +A
Sbjct: 1816 FLPSSPGLVLESPSKPLAPADEDELLPLIPPE-PIS--GGVPFQSVLVNMPTPKSAGIPV 1872
Query: 575 PLDS 578
P S
Sbjct: 1873 PTPS 1876
Score = 55.5 bits (132), Expect = 2e-07
Identities = 66/227 (29%), Positives = 82/227 (36%), Gaps = 28/227 (12%)
Query: 383 PPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDP--GPASPYS--GSGNGGFAFGAEG 438
PP+ GL GAP+ P A +GG + P P P +P + S GG A +
Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP- 1214
Query: 439 PGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTV---NGAP 495
GAP AA G L P+ AP AA P+ G GAP
Sbjct: 1215 KGAPTTPAATPPSPKG--------GLATPSPK--GAPTTPAATPPSPKGGPATPPPKGAP 1264
Query: 496 GPPAA-GARRSSGAGTPRHS-------PTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQ 547
PPAA G TP H T P P G P +GAP P A P
Sbjct: 1265 TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP--PKGAPTPPAATPPSPKG 1322
Query: 548 GPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAP 594
P + P A + P SP P + +S+ PS+ P
Sbjct: 1323 SPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP 1369
Score = 55.5 bits (132), Expect = 2e-07
Identities = 66/237 (27%), Positives = 82/237 (34%), Gaps = 43/237 (18%)
Query: 383 PPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDP--GPASPYS--GSGNGGFAFGAEG 438
PP+ GL + GAP+ P A +GG + P P P +P + S GG A +
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP- 1237
Query: 439 PGAPVGTAAPDDCDFGFDFDFLALDLTVPAAAT-------IWAPFERAAPLPAF------ 485
GAP AA G P AAT + P + AP PA
Sbjct: 1238 KGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297
Query: 486 ---SGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALS 542
S GAP PPAA +P+ SP P P +GAP P
Sbjct: 1298 KGGPATSPPKGAPTPPAA------TPPSPKGSPGTPPP-----------KGAPTPPAVTP 1340
Query: 543 WRP---PQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAPAL 596
P P P + P T S P A P G + PPS PA+
Sbjct: 1341 PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGP--AMTPPSPKRGPAI 1395
Score = 53.1 bits (126), Expect = 8e-07
Identities = 61/216 (28%), Positives = 79/216 (36%), Gaps = 17/216 (7%)
Query: 383 PPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPD----PGPASPYSGSGNGGFAFGAEG 438
PP+ GL + GAP+ P A +GGP+ P P P + S GG A
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH- 1283
Query: 439 PGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAPGPP 498
GAP G P AAT P + +P G GAP PP
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAAT--PPSPKGSP-----GTPPPKGAPTPP 1336
Query: 499 AAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWR--PPQGPVSFPGGA 556
A S GTP T P G P S+ G P S + P P S G
Sbjct: 1337 A--VTPPSPKGTPTLPATTPSSKG-GPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGP 1393
Query: 557 AFSTATSLPSSPAAAACAPLDSGASENSRKPPSASS 592
A + P+SPA +P + A+ +R+ + S
Sbjct: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPS 1429
Score = 51.2 bits (121), Expect = 3e-06
Identities = 141/616 (22%), Positives = 202/616 (32%), Gaps = 145/616 (23%)
Query: 16 GGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAA-ALRLALDQLSALGLGGA 74
GG G P PP A P P+ P P A +L+ GG
Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLK-----------GGL 1278
Query: 75 GDTDEEGAAGDGAAAAGGADGGAAPEPVPPDG---PEAGAPPTLAPAVAPGSLPLLDPNA 131
+GA GG P PP G P A PP+ P +PG+ P P
Sbjct: 1279 ATPPHKGAPNPAVVTPPSPKGG--PATSPPKGAPTPPAATPPS--PKGSPGTPP---PKG 1331
Query: 132 SPPPPPPPRPSPPDVFAGFAPHPAALGPPTLLADQ-----MSVIGSRKKSVNMT------ 180
+P PP PSP A P++ G PT + + + S K MT
Sbjct: 1332 APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKR 1391
Query: 181 -ECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFIVTGRKEDVEMAKRE 239
+P P + + V K T TP +G+ VT V + K
Sbjct: 1392 GPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT----PVSLKKAP 1447
Query: 240 ILSAAEHFSIIRATRSKAGGLPGAAQGPPNLPGQTTIQVRVP--YRVVGLVVGPKGATIK 297
SA K G +++G P LP T + P + V PK A
Sbjct: 1448 ATSA-----------PKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP-- 1494
Query: 298 RIQQRTHTYIVTPGRDKEPVFAVTGMPENVDRAREEIEAHITLRTGAFTDAGPDSDFHAN 357
TP P+ A T +P + + +E+ A
Sbjct: 1495 ----------ATPA----PMGAPT-LPAVIPSSPKEVPA--------------------- 1518
Query: 358 GTDVCLDLLGAAASLWAKTPNQGRRP--PTATAGLRGDTALGAPS----APEAFYAGSRG 411
TP+ R P PTAT + A AP P +
Sbjct: 1519 ------------------TPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK 1560
Query: 412 GPSVPDP--GPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAA 469
P++P P PA+P S + A P G +P +L +P A
Sbjct: 1561 TPAIPTPKEAPATPSSKEASSP---PAVTPSTYKGAPSPK-------------ELLIPPA 1604
Query: 470 ATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRSSGAGTP---RHSPTLPEPGGLRL- 525
T +P E P PA + S G P PA +S TP + SPT P ++
Sbjct: 1605 VTSPSPKEAPTP-PAVTPPSPEKG-PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMG 1662
Query: 526 -ELPLSRRGAPDPVGALSWRP---PQGPVSFPGGAAFSTATSLPSSPAAAACAP--LDSG 579
+P + +G P G + + P S P + P + ++A +P
Sbjct: 1663 ATVPQASKGLPAKKGPTALKEVLVAPAPESTP--IITAPTRKGPQTKKSSATSPPICPDP 1720
Query: 580 ASENSRKPPSASSAPA 595
+++N K P ++ APA
Sbjct: 1721 SAKNGSKGPLSTVAPA 1736
Score = 45.1 bits (105), Expect = 2e-04
Identities = 60/252 (23%), Positives = 85/252 (33%), Gaps = 43/252 (17%)
Query: 383 PPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDPG-------------------PASP 423
PP+ G GAP+ P A +G P P P PA+
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353
Query: 424 YSGSGNGGFAFGAEGPGAPVGTAA--------PDDCDFGFDFDFLALDLTVPAAATIWAP 475
S G EGP P T + P G D T PA +
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK 1413
Query: 476 FERAAPLPAFSGCSTVNGAPGPPAA---GARRSSGAGTPRHSPTLPEPGG---LRLELPL 529
A P+ + G PPA +++ P+ P P G L P
Sbjct: 1414 KAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPP 1473
Query: 530 SRRGAPDPVG-ALSWRPPQGPVS-FPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKP 587
S + P P A S P + P + P GA P+ PA +P + A+ +SR+
Sbjct: 1474 SPKEPPAPKQVATSSSPKKAPATPAPMGA--------PTLPAVIPSSPKEVPATPSSRRD 1525
Query: 588 PSASSAPALARE 599
P A +A L+++
Sbjct: 1526 PIAPTATLLSKK 1537
Score = 44.7 bits (104), Expect = 3e-04
Identities = 61/260 (23%), Positives = 91/260 (35%), Gaps = 55/260 (21%)
Query: 347 DAGPDSDFHANGTDVCLDLLGAAASLWAKTPNQGRRPPTATAGLRGDTALGAPSAPEA-- 404
D+G + + GT L + + L Q +RPPT DT +G S+P +
Sbjct: 774 DSGASATASSKGT--LTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPV 831
Query: 405 ----------FYAGSRGGPSVP-DPGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDF 453
+ GS+ P+ P P SP G A P +P G P
Sbjct: 832 EASFLPENSLSFQGSKDSPATTHSPTPPSP-----KGAPTPSAVTPLSPKGVTLPPK--- 883
Query: 454 GFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRSSGAGTPRH 513
P + + PF + P P P A A S + +P+
Sbjct: 884 -----------ETPTPSVVNLPFPKEGP-----------ATPAPKQAPAL-SMTSSSPKK 920
Query: 514 SPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGPVSFPGGAAFSTATSLPSSPAAAAC 573
+ P P G+ S +GAP P P P S GG A + P+ PAA
Sbjct: 921 ARATPAPKGIPASP--SPKGAPTP-------PAATPPSPKGGPATPSPKWAPTPPAATPP 971
Query: 574 APLDSGASENSRKPPSASSA 593
+P A+ + + P+ +A
Sbjct: 972 SPKGGPATPSPKGAPTPPAA 991
Score = 44.3 bits (103), Expect = 4e-04
Identities = 46/147 (31%), Positives = 56/147 (38%), Gaps = 10/147 (6%)
Query: 23 AAGEDPGPGPA-PPPEGA--QEAAPAPRP---PPEPDDAAAALRLALDQLSALGLGGAGD 76
A P GPA P P+GA AA P P P P A A+ S G A
Sbjct: 968 ATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG-SPAAT 1026
Query: 77 TDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPP-- 134
+GA+ AA G A P+P P A +P P + P L +PP
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT-PSLKGAPTPPAA 1085
Query: 135 PPPPPRPSPPDVFAGFAPHPAALGPPT 161
PP P+ P AP P A PP+
Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPAATPPS 1112
Score = 43.1 bits (100), Expect = 8e-04
Identities = 46/143 (32%), Positives = 58/143 (40%), Gaps = 27/143 (18%)
Query: 34 PPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAGDGAAAAGGA 93
PPP+GA A P P+ A + + A +A T G + GA
Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA--------TPPSPKGGLATPSPKGA 1217
Query: 94 DGGAAPEPVPPDGPEA-----GAPPTLAPAVAPGSLPLLDPNASPPP---PPPPRPSPPD 145
A P P G A GAP T PA P S P P A+PPP P PP +PP
Sbjct: 1218 PTTPAATPPSPKGGLATPSPKGAPTT--PAATPPS-PKGGP-ATPPPKGAPTPPAATPPS 1273
Query: 146 VFAGF-------APHPAALGPPT 161
+ G AP+PA + PP+
Sbjct: 1274 LKGGLATPPHKGAPNPAVVTPPS 1296
Score = 42.4 bits (98), Expect = 0.001
Identities = 38/138 (27%), Positives = 47/138 (34%), Gaps = 20/138 (14%)
Query: 30 PGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAGDGAAA 89
P PP A P+P+ P P A GG +GA A
Sbjct: 966 PAATPPSPKGGPATPSPKGAPTPPAATPPSPK----------GGPATPSPKGAPTPPAVT 1015
Query: 90 AGGADGGAAPEPVPPDG--PEAGAPPTLAPAVAPGSLPLLDPNASPPPP----PPPRPSP 143
G A P P P A PP+ P +P + PL P +P P P P+ P
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPS--PKGSPAATPL--PKGAPTTPAATLPSPKGGP 1071
Query: 144 PDVFAGFAPHPAALGPPT 161
AP P A PP+
Sbjct: 1072 ATPSLKGAPTPPAATPPS 1089
Score = 42.4 bits (98), Expect = 0.001
Identities = 53/183 (28%), Positives = 63/183 (34%), Gaps = 26/183 (14%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPA--PPPEGAQEAAPAPRPPPEPDDAAAAL 59
PS G P G A P PA P P+GA A P P+ A +L
Sbjct: 1017 PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSL 1076
Query: 60 RLALDQLSALG---LGGAGDTDEEGAAGDGAAAAGGADGGAAPEP------------VPP 104
+ A +A GG +GA AA GG A P P
Sbjct: 1077 KGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136
Query: 105 DGPEAGAPPTLAPAVAPGSLPLLDPN---ASPPP---PPPPRPSPPDVFAGFAPHPAALG 158
G A PP AP + P P A+PPP P P +PP G A P+ G
Sbjct: 1137 KGGLATPPPKGAPTTPAATPP--SPKGGLATPPPKGAPTTPAATPPSPKGGLAT-PSPKG 1193
Query: 159 PPT 161
PT
Sbjct: 1194 APT 1196
Score = 42.0 bits (97), Expect = 0.002
Identities = 39/138 (28%), Positives = 47/138 (34%), Gaps = 13/138 (9%)
Query: 25 GEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAG 84
G P PP A P+P+ P P A GG +GA
Sbjct: 938 GAPTPPAATPPSPKGGPATPSPKWAPTPPAAT----------PPSPKGGPATPSPKGAPT 987
Query: 85 DGAAAAGGADGG-AAPEPVPPDGPEAGAPPTL--APAVAPGSLPLLDPNASPPPPPPPRP 141
AA GG A P P P A PP+ +PA P P A+ PP P P
Sbjct: 988 PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP 1047
Query: 142 SPPDVFAGFAPHPAALGP 159
+ + G PAA P
Sbjct: 1048 AATPLPKGAPTTPAATLP 1065
Score = 41.2 bits (95), Expect = 0.003
Identities = 49/181 (27%), Positives = 65/181 (35%), Gaps = 43/181 (23%)
Query: 21 VGAAGEDPGP------GPAP---PPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGL 71
V AA PGP PAP P A +A+P P P A+ L + Q S+
Sbjct: 34 VTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTI---ASTPLEVPFPQSSS--- 87
Query: 72 GGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNA 131
G A P P+ P P + P ++P +L L P
Sbjct: 88 -----------------------GTALPLGTAPEAPTF-LPNLIGPPISPAALALASPMI 123
Query: 132 SPPPPPPPRPSPPDVFAGFAPH---PAALGPPTLLADQMSVIGSRKKSVNMTECVPVPSS 188
+P P S P APH ++ PP LL SV + SV +T P+ S
Sbjct: 124 APTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSV-ITLSAPIAPS 182
Query: 189 E 189
E
Sbjct: 183 E 183
Score = 41.2 bits (95), Expect = 0.003
Identities = 42/146 (28%), Positives = 46/146 (31%), Gaps = 11/146 (7%)
Query: 30 PGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGL----GGAGDTDEEGAAGD 85
P P P+GA A P P+ AA L A L GG +GA
Sbjct: 1023 PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP 1082
Query: 86 GAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSPPD 145
AA GG P P A PP P G L +P P PSP
Sbjct: 1083 PAATPPSPKGG----PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK- 1137
Query: 146 VFAGFAPHPAALGPPTLLADQMSVIG 171
G A P P T A S G
Sbjct: 1138 --GGLATPPPKGAPTTPAATPPSPKG 1161
Score = 40.4 bits (93), Expect = 0.005
Identities = 45/164 (27%), Positives = 51/164 (31%), Gaps = 38/164 (23%)
Query: 22 GAAGEDPGPGPAPP------PEGAQEAAPAPR--------PPPEPDDAAAALRLALDQLS 67
G A P P PP P+G+ A P P+ PP P + AA L
Sbjct: 999 GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP----- 1053
Query: 68 ALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLL 127
+GA AA GG P P A PP P G
Sbjct: 1054 ------------KGAPTTPAATLPSPKGG----PATPSLKGAPTPPAATPPSPKGGPATP 1097
Query: 128 DPNASPPPPPPPRPSPPDVFAGFAPHPAALGPPTLLADQMSVIG 171
P +P PP PSP G A P P T A S G
Sbjct: 1098 SPKGAPMPPAATPPSPK---GGLATPPHKGAPTTPAATPPSPKG 1138
Score = 38.1 bits (87), Expect = 0.026
Identities = 37/131 (28%), Positives = 49/131 (37%), Gaps = 12/131 (9%)
Query: 35 PPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAGDGAAAAGGAD 94
P EG A PAP+ P +++ + A + G+ + +GA AA
Sbjct: 896 PKEGP--ATPAPKQAPALSMTSSSPKKARATPAPKGIPAS--PSPKGAPTPPAATPPSPK 951
Query: 95 GGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSPPDVFA----GF 150
GG P P A PP P G P +P PP PSP A
Sbjct: 952 GG----PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
Query: 151 APHPAALGPPT 161
AP P A+ PP+
Sbjct: 1008 APTPPAVTPPS 1018
Score = 37.0 bits (84), Expect = 0.057
Identities = 44/164 (26%), Positives = 51/164 (31%), Gaps = 31/164 (18%)
Query: 16 GGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAG 75
GG G P PP A P+P+ P P A GG
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK----------GGLA 1118
Query: 76 DTDEEGAAGDGAAAAGGADGGAAPEPVP------------PDGPEAGAPPTLAPAVAPGS 123
+GA AA GG A P P G A PP AP +
Sbjct: 1119 TPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1178
Query: 124 LPLLDPN---ASPPP---PPPPRPSPPDVFAGFAPHPAALGPPT 161
P P A+P P P P +PP G A P+ G PT
Sbjct: 1179 PP--SPKGGLATPSPKGAPTTPAATPPSPKGGLAT-PSPKGAPT 1219
Score = 32.0 bits (71), Expect = 1.8
Identities = 25/80 (31%), Positives = 32/80 (40%), Gaps = 20/80 (25%)
Query: 101 PVPPDGPEAGAPPTLAPAV--------------APGSLPLL-DPNASPPP----PPPPRP 141
P P +GP AP APA+ AP +P P +P P PP P+
Sbjct: 894 PFPKEGPATPAPKQ-APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG 952
Query: 142 SPPDVFAGFAPHPAALGPPT 161
P +AP P A PP+
Sbjct: 953 GPATPSPKWAPTPPAATPPS 972
>gi|113421234 PREDICTED: similar to NG5 protein [Homo sapiens]
Length = 288
Score = 60.5 bits (145), Expect = 5e-09
Identities = 60/171 (35%), Positives = 70/171 (40%), Gaps = 32/171 (18%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRL 61
P G P GG G GGG A EDP +P P P+D +
Sbjct: 44 PFPAGMPGGGSGSDTKGGGSPATPEDP---------------RSPAKPAAPEDPQMPAQP 88
Query: 62 ALDQLSALGLGGAGDTDEEGAAGDGA----AAAGGADG-GAAPEPVPPDGPEAGAPPTLA 116
AL QL DE+GAAG+ AAAGGA G EP P P+ A P L
Sbjct: 89 ALPQLPR----RPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLY 144
Query: 117 PAVAPGSLPLLD-PNASPPPPP---PPRPSPPDVF---AGFA-PHPAALGP 159
P + L P+A PPP P P+PP +F AG A P P GP
Sbjct: 145 PPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGP 195
>gi|113420954 PREDICTED: similar to NG5 protein [Homo sapiens]
Length = 288
Score = 60.5 bits (145), Expect = 5e-09
Identities = 60/171 (35%), Positives = 70/171 (40%), Gaps = 32/171 (18%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRL 61
P G P GG G GGG A EDP +P P P+D +
Sbjct: 44 PFPAGMPGGGSGSDTKGGGSPATPEDP---------------RSPAKPAAPEDPQMPAQP 88
Query: 62 ALDQLSALGLGGAGDTDEEGAAGDGA----AAAGGADG-GAAPEPVPPDGPEAGAPPTLA 116
AL QL DE+GAAG+ AAAGGA G EP P P+ A P L
Sbjct: 89 ALPQLPR----RPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLY 144
Query: 117 PAVAPGSLPLLD-PNASPPPPP---PPRPSPPDVF---AGFA-PHPAALGP 159
P + L P+A PPP P P+PP +F AG A P P GP
Sbjct: 145 PPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGP 195
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 60.5 bits (145), Expect = 5e-09
Identities = 56/202 (27%), Positives = 75/202 (37%), Gaps = 52/202 (25%)
Query: 8 PDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPR------PPPEPDDAAAALRL 61
P+ GGGGGGGG P PA P A+ +PAP P + + + +
Sbjct: 438 PEPGGGGGGGGPSPEREEVRTSPRPASP---ARSGSPAPETTNESVPFAQHSSLDSRIEM 494
Query: 62 ALDQLSALGLGGAGDTDEE--------GAAGDGA-AAAGGADGGAAPEPVPP-------- 104
L + + A DT+EE GA G+ +G G P P P
Sbjct: 495 LLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPT 554
Query: 105 ---------DGPEAGAPPTLAPAVAPGSLPLLD------------PNASPPPPPPPRPSP 143
+ P+A +P + + + D P PPPPPPP P P
Sbjct: 555 GSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPP 614
Query: 144 PDVFA----GFAPH-PAALGPP 160
P A G+ PH PA L PP
Sbjct: 615 PPYLASLPLGYPPHQPAYLLPP 636
Score = 45.1 bits (105), Expect = 2e-04
Identities = 36/129 (27%), Positives = 46/129 (35%), Gaps = 1/129 (0%)
Query: 30 PGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAGDGAAA 89
P +PPP PAP P P+ A + L + A AG T+E +
Sbjct: 1075 PSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPP 1134
Query: 90 AGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSPPDVFAG 149
A G AP P P + P + P P ++ P P PPP P F G
Sbjct: 1135 EPPA-GPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPG 1193
Query: 150 FAPHPAALG 158
A A G
Sbjct: 1194 PASRKAPRG 1202
Score = 30.0 bits (66), Expect = 7.0
Identities = 38/134 (28%), Positives = 47/134 (35%), Gaps = 21/134 (15%)
Query: 396 LGAPSAPEAFYAGSRGGPSVPDPGPAS--PYSGSGNGGFAFGAEGPGAPVGTAAPDDCDF 453
LGA +GS GP P P PA+ + +G+G E P A G C
Sbjct: 521 LGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPKAN-GQNQASPCSS 579
Query: 454 GFDFDFLALDL--TVPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRSSGAGTP 511
G D + D + P A T P ++ P P P PP S G P
Sbjct: 580 GDDMEISDDDRGGSPPPAPT---PPQQPPPPP----------PPPPPPPPYLASLPLGYP 626
Query: 512 RHSPTL---PEPGG 522
H P P P G
Sbjct: 627 PHQPAYLLPPRPDG 640
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 60.5 bits (145), Expect = 5e-09
Identities = 42/136 (30%), Positives = 54/136 (39%), Gaps = 12/136 (8%)
Query: 24 AGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAA 83
+G+ P P P P Q+ P PPP A++ L Q + AG
Sbjct: 486 SGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQ 545
Query: 84 GDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSP 143
AAAA P P+ PT+ P + PG P L P A PPPPPPP S
Sbjct: 546 QQQAAAAAS-----------PGAPQMQGNPTMVP-LPPGVQPPLPPGAPPPPPPPPPGSA 593
Query: 144 PDVFAGFAPHPAALGP 159
++A P P + P
Sbjct: 594 GMMYAPPPPPPPPMDP 609
Score = 43.1 bits (100), Expect = 8e-04
Identities = 38/142 (26%), Positives = 52/142 (36%), Gaps = 24/142 (16%)
Query: 23 AAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGA 82
+ G GP P + AAPA PPP + + + + G + G
Sbjct: 328 SVGSTSGPATTPLASAPRPAAPANNPPP-----PSLMSTTQSRPPWMNSGPSESRPYHGM 382
Query: 83 AGDGAAAAGGADGGAAPEPVPP-DGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRP 141
G G GG + P P+P G G P + N + PPPP +P
Sbjct: 383 HGGGPGGPGGGP-HSFPHPLPSLTGGHGGHP--------------MQHNPNGPPPPWMQP 427
Query: 142 SPPDVFAGFAPHPAA-LGPPTL 162
PP + G PHP GPP +
Sbjct: 428 PPPPMNQG--PHPPGHHGPPPM 447
Score = 40.4 bits (93), Expect = 0.005
Identities = 43/155 (27%), Positives = 51/155 (32%), Gaps = 28/155 (18%)
Query: 4 SLGQPDGGGGGGGGGGGVGAAGEDPGPGPA-------PPPEGAQEAAPAP--RPPPEPDD 54
S +P G GGG GG G P P P+ P + P P +PPP P +
Sbjct: 374 SESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMN 433
Query: 55 AAAALRLALDQLSALGLGGAGDTDE---EGAAGDGAAAAGGADGGAAPEPV----PPDGP 107
G G D+ G G G P P+ PP P
Sbjct: 434 QGP---------HPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPP 484
Query: 108 EAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPS 142
+G PP P P PPPPPPP S
Sbjct: 485 PSGQPPPPPSGPLP---PWQQQQQQPPPPPPPSSS 516
Score = 40.4 bits (93), Expect = 0.005
Identities = 46/165 (27%), Positives = 50/165 (30%), Gaps = 37/165 (22%)
Query: 6 GQPDGGGGGGGGG------------GGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPD 53
G GG GG GGG GG G P PPP P + P P
Sbjct: 381 GMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPG 440
Query: 54 DAAAALRLALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPV----PPDGPEA 109
+DQ G T G G G P P+ PP P +
Sbjct: 441 HHGPP---PMDQY-------LGSTP----VGSGVYRLHQGKGMMPPPPMGMMPPPPPPPS 486
Query: 110 GAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHP 154
G PP G LP PPPPPP P A P P
Sbjct: 487 GQPPP----PPSGPLPPWQQQQQQPPPPPP---PSSSMASSTPLP 524
Score = 32.3 bits (72), Expect = 1.4
Identities = 34/141 (24%), Positives = 58/141 (41%), Gaps = 29/141 (20%)
Query: 221 EPVFIVTGRKEDV-EMAKREILSAAEHFSIIRATRSKAGGLPGAAQGPPNLPGQTTIQVR 279
EP++ G++ + E R+ L H I P A PP + + +V
Sbjct: 84 EPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPAT--RVSDKVM 141
Query: 280 VPY------RVVGLVVGPKGATIKRIQQRTHTYIVTPGR------------------DKE 315
+P VGL++GP+G T+K I++ + I+ G+ + E
Sbjct: 142 IPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKVGRKDGQMLPGEDE 201
Query: 316 PVFAV--TGMPENVDRAREEI 334
P+ A+ ENV +A E+I
Sbjct: 202 PLHALVTANTMENVKKAVEQI 222
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 60.1 bits (144), Expect = 6e-09
Identities = 58/162 (35%), Positives = 63/162 (38%), Gaps = 16/162 (9%)
Query: 6 GQPDGGGGGGGGG-----GGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALR 60
G P G G G G G GA G G GP P PEG + AA PP P AA
Sbjct: 669 GAPGGKGDAGAPGERGPPGLAGAPGLRGGAGP-PGPEGGKGAA----GPPGPPGAAGTPG 723
Query: 61 LALDQLSALGLGGAGDTDEEG-AAGDGAAAAGGADGGAAPE-PVPPDGPEAGAPPTLAPA 118
L GLG G ++G G GA G DG P P+ P GP AG P
Sbjct: 724 LQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGP-AGQPGDKGEG 782
Query: 119 VAPGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPP 160
APG + P SP P P AGF P G P
Sbjct: 783 GAPGLPGIAGPRGSPGERGETGPPGP---AGFPGAPGQNGEP 821
Score = 54.3 bits (129), Expect = 3e-07
Identities = 156/660 (23%), Positives = 199/660 (30%), Gaps = 125/660 (18%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGED--PGPGPAPPPEGAQEAAPAP------------- 46
PS P G G G G G +G PG P P G + A P
Sbjct: 211 PSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDG 270
Query: 47 RPPPEPDDAAAALR----LALDQLSALGLGGAGDTDEEGAAG-DGAAAAGGADG--GAAP 99
R + + A L+ L + + +G G E G G GAA A G DG G+
Sbjct: 271 RNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDG 330
Query: 100 EPVPPDGP-------EAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSPPDVFAGFAP 152
+P PP P GA + PA +PGS P P P G
Sbjct: 331 QPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGING 390
Query: 153 HPAALGP--PTLLADQMSVIGSRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTN 210
P G P + ++G+R P P+ + G G + A N
Sbjct: 391 SPGGKGEMGPAGIPGAPGLMGARGP--------PGPAGAN-----GAPGLRGGAGEPGKN 437
Query: 211 TYIKTP----VRGEEPVFIVTGRKEDVEMAKREILSAAEHFSIIRATRSKAGGLPGAA-- 264
P RGE + V G K E A GLPGAA
Sbjct: 438 GAKGEPGPRGERGEAGIPGVPGAK-------------GEDGKDGSPGEPGANGLPGAAGE 484
Query: 265 ---------QGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIVTPGRDKE 315
GP +PG+ + R GP+GA + PGRD
Sbjct: 485 RGAPGFRGPAGPNGIPGE---KGPAGERGAPGPAGPRGAAGE------------PGRDGV 529
Query: 316 PVF-AVTGMPENVDRAREEIEAHITLRTGAFTDAGPDSDFHANGTDVCLDLLGAAASLWA 374
P + GMP + + + G GP G + G + A
Sbjct: 530 PGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGA 589
Query: 375 KTPN-----QGRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDPGPASPYSGSGN 429
N G P G G+T P P G +G P P G+G
Sbjct: 590 PGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTG-PGGDKGDTGPPGPQGLQGLPGTGG 648
Query: 430 GGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCS 489
G G P G A G AP ER P +G
Sbjct: 649 PPGENGKPGEPGPKGDAGAPGAPGG--------------KGDAGAPGERGP--PGLAGAP 692
Query: 490 TVNGAPGPPA-AGARRSSG-------AGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGAL 541
+ G GPP G + ++G AGTP E GGL P +G P GA
Sbjct: 693 GLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGAD 752
Query: 542 SW------RPPQGPVSFPGGAAFSTATSLPSSPAAAACA-PLDSGASENSRKPPSASSAP 594
R P GP+ PG A +P A P S PP + P
Sbjct: 753 GVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFP 812
Score = 50.1 bits (118), Expect = 7e-06
Identities = 53/177 (29%), Positives = 68/177 (38%), Gaps = 21/177 (11%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRL 61
P + GQ +G GG G G G GE PG A PP G+ A P + + +
Sbjct: 812 PGAPGQ-NGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPG 870
Query: 62 ALDQLSALGL-------------GGAGDTDEEGAAGD-GAAAAGGADGGAAPEPVPPDGP 107
A A GL G +G ++G G G A G+ G + P+
Sbjct: 871 AAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPG 930
Query: 108 EAGAPPTLAPAVAPGSLPLLDPN-----ASPPPPPPPRPSP-PDVFAGFAPHPAALG 158
E G+P P APG L + A PP P PR SP P G + P A G
Sbjct: 931 EKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANG 987
Score = 46.2 bits (108), Expect = 9e-05
Identities = 52/162 (32%), Positives = 60/162 (37%), Gaps = 17/162 (10%)
Query: 2 PSSLGQP--DGGGGGGGGGGGVGAAGEDPGPG-PAPPPEGAQEAAPAPRPPPEPDDAAAA 58
P S G P DG GG G G G+ G PG P PP R P A A
Sbjct: 1016 PGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGA 1075
Query: 59 LRLALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPA 118
A + + G GD E G GAA G G P P GAP + PA
Sbjct: 1076 PGPAGSRGAPGPQGPRGDKGETGER--GAAGIKGHRGF-------PGNP--GAPGSPGPA 1124
Query: 119 VAPGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPP 160
G++ P P P PS P G + HP +GPP
Sbjct: 1125 GQQGAIGSPGPAG---PRGPVGPSGPPGKDGTSGHPGPIGPP 1163
Score = 43.9 bits (102), Expect = 5e-04
Identities = 54/192 (28%), Positives = 63/192 (32%), Gaps = 50/192 (26%)
Query: 1 MPSSLGQPDGGG--GGGGGGGGVGAAGEDPGPGPAPPPEGAQE------AAPAPRPPPEP 52
+P G P G G G G G GA G PGP P + + A PA P P
Sbjct: 1021 LPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAG 1080
Query: 53 DDAAAALRLALDQLSALGLGGAGDTDEEGAAG-------------------DGAAAAGGA 93
A + G G+T E GAAG G A G+
Sbjct: 1081 SRGAPGPQGPR--------GDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGS 1132
Query: 94 DGGAAPE-PVPPDGPE-----AGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSPPDVF 147
G A P PV P GP +G P + P G+ SP P P P P
Sbjct: 1133 PGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGP--- 1189
Query: 148 AGFAPHPAALGP 159
P A GP
Sbjct: 1190 ------PGAPGP 1195
Score = 43.5 bits (101), Expect = 6e-04
Identities = 49/164 (29%), Positives = 58/164 (35%), Gaps = 29/164 (17%)
Query: 8 PDGGGGGGGGGGGVGAAGEDPGPGPAPP--PEGAQEAAPAPRPPPEPDDAAAALRLALDQ 65
P G G GG G G G+D GP P P G PA +P + + A L
Sbjct: 739 PKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPG-----PAGQPGDKGEGGAPGLPGIAGP 793
Query: 66 LSALGLGGAGDTDEEGAAG-DGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSL 124
+ G G+T G AG GA G GG P + E G P P PG
Sbjct: 794 RGSPG--ERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGP---PG-- 846
Query: 125 PLLDPNASPPPPPPPR--------PSPPDVFAGFAPHPAALGPP 160
+ P PP P+ P P AGF GPP
Sbjct: 847 -----GSGPAGPPGPQGVKGERGSPGGPGA-AGFPGARGLPGPP 884
Score = 42.7 bits (99), Expect = 0.001
Identities = 73/262 (27%), Positives = 83/262 (31%), Gaps = 46/262 (17%)
Query: 349 GPDSDFHANGTDVCLDLLGAAASLWAKTPNQGRRPPTATAGLRG-------DTALGAPSA 401
GP ANG G AK G R AG+ G D G+P
Sbjct: 414 GPPGPAGANGAPGLRGGAGEPGKNGAKG-EPGPRGERGEAGIPGVPGAKGEDGKDGSPGE 472
Query: 402 PEAF----YAGSRGGPSVPDPGPASPYSGSGNGGFAF--GAEGPGAPVGTAAPDDCDFGF 455
P A AG RG P GPA P G G A GA GP P G A D
Sbjct: 473 PGANGLPGAAGERGAPGFR--GPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD--- 527
Query: 456 DFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRSSG-AGTPRHS 514
VP P R +P G +G PGPP G++ SG G P S
Sbjct: 528 ---------GVPG-----GPGMRG--MPGSPGGPGSDGKPGPP--GSQGESGRPGPPGPS 569
Query: 515 PTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACA 574
+PG + P GAP G GP PG + P P
Sbjct: 570 GPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPG----KNGETGPQGPP----G 621
Query: 575 PLDSGASENSRKPPSASSAPAL 596
P G + PP L
Sbjct: 622 PTGPGGDKGDTGPPGPQGLQGL 643
Score = 40.0 bits (92), Expect = 0.007
Identities = 63/237 (26%), Positives = 73/237 (30%), Gaps = 46/237 (19%)
Query: 380 GRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPD-----PGPASPYSGSGNGGFAF 434
G R + G +GD G P P A + GP P PGPA G GG A
Sbjct: 729 GERGGLGSPGPKGDK--GEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGG-AP 785
Query: 435 GAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATI-WAPFERAAP-------LPAFS 486
G G P G+ + P A AP + P P
Sbjct: 786 GLPGIAGPRGSPGERG------------ETGPPGPAGFPGAPGQNGEPGGKGERGAPGEK 833
Query: 487 GCSTVNGAPGPPA----AGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALS 542
G G GPP AG G R SP P G RG P P G+
Sbjct: 834 GEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFP-----GARGLPGPPGSNG 888
Query: 543 WRPPQGPVSFPG-----GAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAP 594
P GP PG G A +T P SP + P + P A P
Sbjct: 889 NPGPPGPSGSPGKDGPPGPAGNTGA--PGSPGVS--GPKGDAGQPGEKGSPGAQGPP 941
Score = 38.5 bits (88), Expect = 0.020
Identities = 56/187 (29%), Positives = 64/187 (34%), Gaps = 33/187 (17%)
Query: 1 MPSSLGQP--DGGGGGGGGGGGVGAAGEDPGP---GPAPPPEGAQEAAPA-PRPPPEPDD 54
+P + G+ DG G G G GAAGE P GPA P E PA R P P
Sbjct: 457 VPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGP-- 514
Query: 55 AAAALRLALDQLSALGL-GGAGDTDEEGAAG----DGAAAAGGADG-GAAPEPVPPDGPE 108
A R A + G+ GG G G+ G DG G+ G P P P GP
Sbjct: 515 --AGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPR 572
Query: 109 A--------------GAPPTLAPAVAPGSLPLLDP---NASPPPPPPPRPSPPDVFAGFA 151
GAP PG P N P PP P+ P G
Sbjct: 573 GQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDT 632
Query: 152 PHPAALG 158
P G
Sbjct: 633 GPPGPQG 639
Score = 37.7 bits (86), Expect = 0.033
Identities = 62/220 (28%), Positives = 69/220 (31%), Gaps = 43/220 (19%)
Query: 392 GDTALGAPSAPEAF-------YAGSRGGPSVPDP-GPASPYSGSGNGGFAFGAEGPGAPV 443
G A G P P A G RGG P P G G G G G +GP P
Sbjct: 706 GKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVP-GKDGPRGPT 764
Query: 444 GTAAPDDCDFGFDFDFLALDLTVPAAATIWAP-------FERAAPLPA-FSGCSTVNGAP 495
G P G D + P I P E P PA F G NG P
Sbjct: 765 GPIGPPG-PAGQPGD--KGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEP 821
Query: 496 GPPA-AGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGPVSFPG 554
G GA G G P P + P G G P G + +G PG
Sbjct: 822 GGKGERGAPGEKGEGGP---PGVAGPPG--------GSGPAGPPGPQGVKGERGSPGGPG 870
Query: 555 GAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAP 594
A F A LP P S + PP S +P
Sbjct: 871 AAGFPGARGLPGPP-----------GSNGNPGPPGPSGSP 899
Score = 36.6 bits (83), Expect = 0.075
Identities = 45/183 (24%), Positives = 59/183 (32%), Gaps = 22/183 (12%)
Query: 392 GDTALGAPSAPEAFYAGSRG-GPSVP--DPGPASPYSGSGNGGFAFGAEGPGAPVGTAAP 448
G+ P P A G GP P DPGP +G+ G PG+P
Sbjct: 82 GECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGIC 141
Query: 449 DDCDFG---FDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRS 505
+ C G + + + D+ A L + G + G PGPP
Sbjct: 142 ESCPTGPQNYSPQYDSYDVKSGVA---------VGGLAGYPGPAGPPGPPGPPGTSGHPG 192
Query: 506 SGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGPVSFPGGAAFSTATSLP 565
S G+P + EPG G P P GA+ P G G LP
Sbjct: 193 S-PGSPGYQGPPGEPG------QAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLP 245
Query: 566 SSP 568
P
Sbjct: 246 GPP 248
Score = 35.0 bits (79), Expect = 0.22
Identities = 43/153 (28%), Positives = 48/153 (31%), Gaps = 47/153 (30%)
Query: 408 GSRGGPSVPD-PGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTV 466
GS G P P PGP P +G G G GP P G
Sbjct: 1038 GSPGAPGAPGHPGPPGPVGPAGKSGDR-GESGPAGPAG---------------------- 1074
Query: 467 PAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAA-GARRSSG----AGTPRHSPTLPEPG 521
AP PA S GAPGP G + +G AG H PG
Sbjct: 1075 -------------APGPAGS-----RGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPG 1116
Query: 522 GLRLELPLSRRGAPDPVGALSWRPPQGPVSFPG 554
P ++GA G R P GP PG
Sbjct: 1117 APGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPG 1149
Score = 33.9 bits (76), Expect = 0.48
Identities = 38/157 (24%), Positives = 52/157 (33%), Gaps = 8/157 (5%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRL 61
P++ +P G G G G G G PG P G + +P PP + +
Sbjct: 92 PTAPTRPPNGQGPQGPKGDPGPPGI-PGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQN 150
Query: 62 ALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAP 121
Q + + + G A G A G G P P G+P + P
Sbjct: 151 YSPQYDSYDV-------KSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPP 203
Query: 122 GSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALG 158
G P+ P PP PS P G + P G
Sbjct: 204 GEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPG 240
Score = 33.9 bits (76), Expect = 0.48
Identities = 57/207 (27%), Positives = 66/207 (31%), Gaps = 35/207 (16%)
Query: 393 DTALGAPSAPEAFYAGSRGGPSVPDPGPASPYSGS-GNGGF--------AFGAEGPGAPV 443
D G A Y G G P P P S + GS G+ G+ G GP P
Sbjct: 159 DVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPP 218
Query: 444 GTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAPG-PPAAGA 502
G P G D + + P ER P P G G PG P G
Sbjct: 219 GAIGPSG-PAGKDGE----------SGRPGRPGERGLPGP--PGIKGPAGIPGFPGMKGH 265
Query: 503 RRSSGAGTPRHSPTLPEPGGLRLELPL-SRRGAPDPVGALSWRPPQGPVSFPG------- 554
R G + P GL+ E L GAP P+G +G PG
Sbjct: 266 RGFDGRNGEKGETGAP---GLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGN 322
Query: 555 -GAAFSTATSLPSSPAAAACAPLDSGA 580
GA S P P A P GA
Sbjct: 323 DGARGSDGQPGPPGPPGTAGFPGSPGA 349
Score = 33.9 bits (76), Expect = 0.48
Identities = 54/201 (26%), Positives = 63/201 (31%), Gaps = 37/201 (18%)
Query: 389 GLRGDTALGAPSAPEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGPGAPVGTAAP 448
G G P P A G+ G P V P + G A G G P+G A
Sbjct: 894 GPSGSPGKDGPPGP-AGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGI 952
Query: 449 DDCDFGFDFDFLALDLTVPAAATIWAPFERAAP----------LPAFSGCSTVNGAPGPP 498
A L P P R +P P +G S G PGP
Sbjct: 953 TG----------ARGLAGPPG----MPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQ 998
Query: 499 A----AGARRSSGAGTPRHSPTLP----EPGGLRLELPLSRRGAPDPVGALSWRPPQGPV 550
AG G S LP PGG + G+P GA P GPV
Sbjct: 999 GLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGG---KGDRGENGSPGAPGAPGHPGPPGPV 1055
Query: 551 SFPGGAAFSTATSLPSSPAAA 571
P G + S P+ PA A
Sbjct: 1056 G-PAGKSGDRGESGPAGPAGA 1075
Score = 32.3 bits (72), Expect = 1.4
Identities = 53/204 (25%), Positives = 59/204 (28%), Gaps = 41/204 (20%)
Query: 380 GRRPPTATAGLRGDTAL-GAPSAPEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEG 438
G P AG+ G L G P P G RG P P SG G G
Sbjct: 942 GAPGPLGIAGITGARGLAGPPGMP-----GPRGSPG---PQGVKGESGKPGANGLSGERG 993
Query: 439 PGAP------VGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVN 492
P P GTA D D L P +P G N
Sbjct: 994 PPGPQGLPGLAGTAGEPGRDGNPGSDGL--------------PGRDGSP--GGKGDRGEN 1037
Query: 493 GAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGP--- 549
G+PG P A G P + G P GAP P G+ PQGP
Sbjct: 1038 GSPGAPGAPGH----PGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGD 1093
Query: 550 ---VSFPGGAAFSTATSLPSSPAA 570
G A P +P A
Sbjct: 1094 KGETGERGAAGIKGHRGFPGNPGA 1117
Score = 31.2 bits (69), Expect = 3.1
Identities = 33/110 (30%), Positives = 39/110 (35%), Gaps = 11/110 (10%)
Query: 343 GAFTDAGPDSDFHANGTDVCLDLLGAAASLWAKTPNQGRRPPTATAGLRGDTALGAPSAP 402
G AG D +G G A S A P QG R G RG +
Sbjct: 1053 GPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGP-QGPRGDKGETGERGAAGIKGHRG- 1110
Query: 403 EAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCD 452
+ G+ G P PGPA G+ G A GP PVG + P D
Sbjct: 1111 ---FPGNPGAPG--SPGPAGQQGAIGSPGPA----GPRGPVGPSGPPGKD 1151
Score = 30.4 bits (67), Expect = 5.3
Identities = 32/91 (35%), Positives = 36/91 (39%), Gaps = 25/91 (27%)
Query: 378 NQGRRPPTATAGLRGDTALGAPSAPEAFYAGSRG--GPSVPD--------PGPASPYSGS 427
N G AG +G A+G+P AG RG GPS P PGP P
Sbjct: 1114 NPGAPGSPGPAGQQG--AIGSPGP-----AGPRGPVGPSGPPGKDGTSGHPGPIGPPGPR 1166
Query: 428 GNGGFAFGAEG-------PGAPVGTAAPDDC 451
GN G G+EG PG P AP C
Sbjct: 1167 GNRGER-GSEGSPGHPGQPGPPGPPGAPGPC 1196
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 60.1 bits (144), Expect = 6e-09
Identities = 50/148 (33%), Positives = 62/148 (41%), Gaps = 18/148 (12%)
Query: 26 EDPGPGPAPPPEGAQEA--APAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAA 83
ED P P P + +E PRPPPEP A L+ Q + + L GD
Sbjct: 570 EDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLS--QTAEVALDLVGDRTPTSEK 627
Query: 84 GDGAAAAGGADGGAAPEPVPP------DGPEA-----GAPPTLAPAVAPGSLPLLDPNAS 132
D + G D + + +P D P+ GA AP+V +LPL P
Sbjct: 628 MDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGF 687
Query: 133 PPPPPPPRPSPPDVFAGFAPHPAALGPP 160
PP PPPP P PP GF P P L PP
Sbjct: 688 PPLPPPPPPPPPQ--PGF-PMPPPLPPP 712
Score = 42.0 bits (97), Expect = 0.002
Identities = 38/144 (26%), Positives = 43/144 (29%), Gaps = 58/144 (40%)
Query: 32 PAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAGDGAAAAG 91
P PPP G P P PPP
Sbjct: 680 PLPPPPGFPPLPPPPPPPPPQP-------------------------------------- 701
Query: 92 GADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPP--PPPRPSPPDVFAG 149
G P P+PP P PP PAV PL P PPPP PP P PP +F
Sbjct: 702 ---GFPMPPPLPPPPPP---PPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLF-- 753
Query: 150 FAPHPAALGPPTLLADQMSVIGSR 173
P + D V+G +
Sbjct: 754 ----------PVMQVDMSHVLGGQ 767
Score = 40.8 bits (94), Expect = 0.004
Identities = 50/170 (29%), Positives = 58/170 (34%), Gaps = 39/170 (22%)
Query: 23 AAGEDPGPGPAPP-PEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEG 81
A E P PP P G +E A + PP EP G
Sbjct: 1199 APEERPSMLDEPPLPVGVEEPADSREPPEEP----------------------------G 1230
Query: 82 AAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTL-APAVAPGSLPL-LDPNASPPPPPPP 139
+ +GA E PP PE L P LPL L P PP PP P
Sbjct: 1231 LSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRP 1290
Query: 140 RPSPPDVFAGFAPHPAALGPPTLLADQ-----MSVIGSRKKSVNMTECVP 184
PP+ A HP+ PP LA+ + GS KS TE VP
Sbjct: 1291 PSPPPEPETTDASHPSV--PPEPLAEDHPPHTPGLCGSLAKS-QSTETVP 1337
Score = 38.1 bits (87), Expect = 0.026
Identities = 44/154 (28%), Positives = 54/154 (35%), Gaps = 33/154 (21%)
Query: 19 GGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTD 78
G VG G GP P+ + A A PPP A + A +
Sbjct: 355 GAVGGTGGSSGPPFKAQPQDS--ATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPE 412
Query: 79 EEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPP 138
E A AA G D G + A APP L PA +P A P P
Sbjct: 413 EPTAT----AAFGARDSG--------EFRRAPAPPPLPPA---------EPLAKEKPGTP 451
Query: 139 PRPSPPDVFA---------GFAPHPA-ALGPPTL 162
P P PPD + G++P P + G PTL
Sbjct: 452 PGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTL 485
Score = 34.3 bits (77), Expect = 0.37
Identities = 37/125 (29%), Positives = 42/125 (33%), Gaps = 16/125 (12%)
Query: 28 PGPGPAPPPEGAQEAAPAPRPPPEPDDAAAAL--------RLALDQLSALGLGGAGDTDE 79
P P P AQ AP P PP P A+ R S L L G
Sbjct: 1438 PLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGP----- 1492
Query: 80 EGAAGDGAAAAGGADGGAAP-EPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPP 138
A AA G + P +P P P P T+ +P P P PPPP
Sbjct: 1493 --LVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPP 1550
Query: 139 PRPSP 143
P P P
Sbjct: 1551 PPPPP 1555
Score = 32.0 bits (71), Expect = 1.8
Identities = 63/247 (25%), Positives = 85/247 (34%), Gaps = 48/247 (19%)
Query: 407 AGSRGGPSVP-DPGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLT 465
A S+ +VP PG P SG +G + PG+P AP +
Sbjct: 1328 AKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSP--------------S 1373
Query: 466 VPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRL 525
+ + P + P FS S P P RR +G P SP L E GL L
Sbjct: 1374 LSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSG-PLASPVLLET-GLPL 1431
Query: 526 ELPLSRRGAPDPVGALSWRPPQGPVSFPG--GAAFSTATSLP---SSPAAAACAPLDSGA 580
LPL P P+ P++ P A T LP +P A+ P+
Sbjct: 1432 PLPL-----PLPL----------PLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKP 1476
Query: 581 SENSRKPPSASS----------APALARECVVCAEGEVMAALVPCGHNLFCMDCAVRICG 630
R PPS S AL RE ++ G+ + P H+ + R G
Sbjct: 1477 GRPRRSPPSMLSLDGPLVRPPAGAALGRE-LLLLPGQPQTPVFPSTHDPRTVTLDFRNAG 1535
Query: 631 KSEPECP 637
P P
Sbjct: 1536 IPAPPPP 1542
Score = 31.6 bits (70), Expect = 2.4
Identities = 16/41 (39%), Positives = 18/41 (43%)
Query: 28 PGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSA 68
P P P PP G P P PPP P A A+ + L A
Sbjct: 692 PPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPA 732
Score = 31.6 bits (70), Expect = 2.4
Identities = 34/123 (27%), Positives = 45/123 (36%), Gaps = 16/123 (13%)
Query: 28 PGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQ-LSALGLGGAGDTDEE-----G 81
P P+PPPE A P PPEP LA D GL G+ +
Sbjct: 1287 PPRPPSPPPEPETTDASHPSVPPEP--------LAEDHPPHTPGLCGSLAKSQSTETVPA 1338
Query: 82 AAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRP 141
G +GG+ G + P P P + P +P+++ G LP P P
Sbjct: 1339 TPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAP--SPSLSSGGLPRTPGRDFSFTPTFSEP 1396
Query: 142 SPP 144
S P
Sbjct: 1397 SGP 1399
Score = 31.2 bits (69), Expect = 3.1
Identities = 39/137 (28%), Positives = 49/137 (35%), Gaps = 29/137 (21%)
Query: 466 VPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRSSG--AGTPRHSPTLPEPGGL 523
V A A A F ++ LP F G+ GPP + S A TP + P PG
Sbjct: 336 VTAVAGATAAFRGSSDLP-FGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFK 394
Query: 524 RLELPLSRRGAPDPVGALSWRPPQGPVS-FPGGAAFSTATSLPSSPAAAACAPLDSGASE 582
++ P Q PV+ FP TAT AA DSG
Sbjct: 395 S-----------------AFSPYQTPVAHFPPPPEEPTAT--------AAFGARDSGEFR 429
Query: 583 NSRKPPSASSAPALARE 599
+ PP A LA+E
Sbjct: 430 RAPAPPPLPPAEPLAKE 446
Score = 30.4 bits (67), Expect = 5.3
Identities = 52/177 (29%), Positives = 64/177 (36%), Gaps = 29/177 (16%)
Query: 6 GQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPP-------PEPDDAAAA 58
G+P GG G P PAP P + + PR P P + +
Sbjct: 1342 GEPPLSGGSSGLSLSSPQVPGSPFSYPAPSP--SLSSGGLPRTPGRDFSFTPTFSEPSGP 1399
Query: 59 LRLALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPA 118
L L + L G DE +G A+ G P P+P P A A A
Sbjct: 1400 LLLPVCPLPT------GRRDER--SGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQA 1451
Query: 119 VAPGSLPLLDP---NASPPP----PPPPRPSPPDVFA-----GFAPHPAALGPPTLL 163
AP LP L P + PPP P PR SPP + + P AALG LL
Sbjct: 1452 RAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLL 1508
Score = 30.0 bits (66), Expect = 7.0
Identities = 38/122 (31%), Positives = 41/122 (33%), Gaps = 18/122 (14%)
Query: 28 PGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAGDGA 87
PG PP P RPP A AAL L L L G T + D
Sbjct: 1476 PGRPRRSPPSMLSLDGPLVRPP-----AGAALGREL-----LLLPGQPQTPVFPSTHDPR 1525
Query: 88 AAA---GGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLD-PNASPPPPPPPRPSP 143
A A P P+PP P PP P V P LP + N P PP P
Sbjct: 1526 TVTLDFRNAGIPAPPPPLPPQPP----PPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRG 1581
Query: 144 PD 145
D
Sbjct: 1582 RD 1583
>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
Length = 947
Score = 59.7 bits (143), Expect = 8e-09
Identities = 56/191 (29%), Positives = 70/191 (36%), Gaps = 50/191 (26%)
Query: 1 MPSSLGQP----DGGGGGGGGGGGVGAAGEDPGPGPAPPP----------------EGAQ 40
+PS LG+P +GGGGGG GGG G +GE G P PPP G +
Sbjct: 153 VPSKLGEPPPLGEGGGGGGEGGGAGGGSGEREGGAPQPPPPRGWRGKGVRAQQRGGSGGE 212
Query: 41 EAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAGD-----------GAAA 89
A+P+P R + ++ G GG G +EG AAA
Sbjct: 213 GASPSPSSSSAGKTPGTGSRNSGSGVAGGGSGGGGSYWKEGCLQSELIQFHLKKERAAAA 272
Query: 90 AGGAD------GGAAPEPVPPDGPE--------AGAPPTLAPAVAP-----GSLPLLDPN 130
A A GG++ P GP A A P A A P GS
Sbjct: 273 AAAAQMHAKNGGGSSSRSSPVSGPPAVCETLAVASASPMAAAAEGPQQSAEGSASGGGMQ 332
Query: 131 ASPPPPPPPRP 141
A+ PP P P
Sbjct: 333 AAAPPSSQPHP 343
Score = 55.8 bits (133), Expect = 1e-07
Identities = 39/105 (37%), Positives = 44/105 (41%), Gaps = 16/105 (15%)
Query: 12 GGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPA----------PRPPPEPDDAAAALRL 61
GGGGG A + PG P GA EAAPA P PP EP ++
Sbjct: 97 GGGGGAEKATPLAPKGAAPGAVQPVAGA-EAAPAATLAALGGRRPGPPEEPPRELESVPS 155
Query: 62 ALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDG 106
L + LG GG G G G GA G G AP+P PP G
Sbjct: 156 KLGEPPPLGEGGGG-----GGEGGGAGGGSGEREGGAPQPPPPRG 195
Score = 33.5 bits (75), Expect = 0.63
Identities = 34/143 (23%), Positives = 47/143 (32%), Gaps = 20/143 (13%)
Query: 17 GGGGVGAAGEDPGPGPAPP---PEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGG 73
GG A P PEG+ + P P D++ +A + S +G G
Sbjct: 7 GGAAPATAAASPAAAATEARLHPEGSSRKQQRAQSPARPRDSSLRQTIAATR-SPVGAGT 65
Query: 74 AGDTDEE--------------GAAGDGAAAAGGADGGAAPEPVPPDGPEAGA--PPTLAP 117
++ + G A+ GG G P+ P G GA P A
Sbjct: 66 KLNSVRQQQLQQQQQQGNKTGSRTGPPASIRGGGGGAEKATPLAPKGAAPGAVQPVAGAE 125
Query: 118 AVAPGSLPLLDPNASPPPPPPPR 140
A +L L PP PPR
Sbjct: 126 AAPAATLAALGGRRPGPPEEPPR 148
>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform a [Homo sapiens]
Length = 1214
Score = 58.9 bits (141), Expect = 1e-08
Identities = 47/136 (34%), Positives = 56/136 (41%), Gaps = 24/136 (17%)
Query: 30 PGPAPPPEGAQEAAPAPRP-PPEPDDAAAALRLALDQLSALGL--GGAGDTDEEGAAGDG 86
P PA PP G+Q P PP A A + + G G G +++ G AG
Sbjct: 961 PPPALPP-GSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGST 1019
Query: 87 AAA-----AGGADGGAAPEPVPPDGPEAGAP-------PTLAPAVAPGS--------LPL 126
A AG GA P VPP GP +P P++ P PGS PL
Sbjct: 1020 AGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAGNAPL 1079
Query: 127 LDPNASPPPPPPPRPS 142
P PPPPPPP PS
Sbjct: 1080 GLPFGMPPPPPPPAPS 1095
Score = 35.8 bits (81), Expect = 0.13
Identities = 42/151 (27%), Positives = 52/151 (34%), Gaps = 41/151 (27%)
Query: 72 GGAGDTDEEGAAGDGAAAAGGADGGAAP-------EPVPPDGPEAGAPPTLAPAVAPGSL 124
G AG G A A+ G AP E + G AG P PA AP
Sbjct: 976 GAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAG-PQQQQPAGAP--- 1031
Query: 125 PLLDPNASPPPPPPPRP----------SPPDVFAGFAP---HPAALG------------P 159
P A PP PPP P +PP + G P HP G P
Sbjct: 1032 ---QPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAGNAPLGLPFGMPPP 1088
Query: 160 PTLLADQMSVIGSRKKSVNMTECVPVPSSEH 190
P A + GS S+++ +P P + H
Sbjct: 1089 PPPPAPSIIPFGSLADSISIN--LPAPPNLH 1117
Score = 31.2 bits (69), Expect = 3.1
Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 9/51 (17%)
Query: 104 PDGPEAGAPPTLAPAVA--------PGSLPLLDPNASPPPPPPPRPSPPDV 146
P GP G+ +PA+ P + PL DP +P PP P PSP V
Sbjct: 1158 PLGPGLGSAAAQSPAIVAAVQGNLLPSASPLPDPG-TPLPPDPTAPSPGTV 1207
>gi|12751477 forkhead box L2 [Homo sapiens]
Length = 376
Score = 58.5 bits (140), Expect = 2e-08
Identities = 57/169 (33%), Positives = 63/169 (37%), Gaps = 37/169 (21%)
Query: 11 GGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAA-----PAPRPPPEPDDAAAALRLALDQ 65
G GG GG GV AG D G G PP+ Q P P+PP A+ + A
Sbjct: 168 GAGGAAGGCGVAGAGAD-GYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAA-- 224
Query: 66 LSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPP-------TLAPA 118
AA AAAAG GAA GP A P L P
Sbjct: 225 ---------------AAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYTRVQSMALPPG 269
Query: 119 VAPGSLPLLDPNASPPPPPPPRPSP--PDVFAGFAPHPA-----ALGPP 160
V L P A+PPPPP P P P + A AP PA A PP
Sbjct: 270 VVNSYNGLGGPPAAPPPPPHPHPHPHAHHLHAAAAPPPAPPHHGAAAPP 318
Score = 32.7 bits (73), Expect = 1.1
Identities = 16/30 (53%), Positives = 16/30 (53%), Gaps = 2/30 (6%)
Query: 6 GQPDGGGGGGGGGGGVGAAGEDPGPGPAPP 35
G P G GGGGGG G A E P P PP
Sbjct: 29 GPPPSPGKGGGGGG--GTAPEKPDPAQKPP 56
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 58.2 bits (139), Expect = 2e-08
Identities = 148/570 (25%), Positives = 175/570 (30%), Gaps = 101/570 (17%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRL 61
P+ P G GG G G GA GE GP A PEGAQ P P P A A+
Sbjct: 352 PAGPPGPVGPAGGPGFPGAPGAKGE-AGPTGARGPEGAQGPRGEPGTPGSPGPAGAS--- 407
Query: 62 ALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPP------TL 115
G G GA G A A G A P P P GP+ P T
Sbjct: 408 ----------GNPGTDGIPGAKG-SAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTG 456
Query: 116 APAVAPGSLPLLDPNASPPPPPP---PRPSPPDVFAGFAPHPAALGPPTLLADQMSVIGS 172
P +A G P P P P P P+ + G P +GP + G
Sbjct: 457 EPGIA-GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP-------IGPPGE 508
Query: 173 RKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFI----VTG 228
R N P + +A G G + + A P R EP +TG
Sbjct: 509 RGAPGNR----GFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTG 564
Query: 229 RKEDVEMAKREILSAAEHFSIIRATRSKAGGLPGAAQGPPNLPGQTTIQ-VRVPYRVVGL 287
R D + K G P A G PG Q R V+G
Sbjct: 565 RPGDA------------------GPQGKVG--PSGAPGEDGRPGPPGPQGARGQPGVMGF 604
Query: 288 VVGPKGATIKRIQQRTHTYIVTPGRDKEPVFAVTGMPENVDRAREEIEAHITLRTGAFTD 347
GPKGA + PG+ E + G P ++ E G
Sbjct: 605 -PGPKGANGE------------PGKAGEK--GLPGAPGLRGLPGKDGETGAAGPPGPAGP 649
Query: 348 AGPDSDFHANGTDVCLDLLGAAASLWAKTPNQGRRP-PTATAGLRGDTALGAPSAPEAFY 406
AG + A G L G P +G +P G G L P F
Sbjct: 650 AGERGEQGAPGPSGFQGLPGPPG-----PPGEGGKPGDQGVPGEAGAPGLVGPRGERGF- 703
Query: 407 AGSRGGPSVPD-PGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLT 465
G RG P GP G G GA GP P G P G + A +
Sbjct: 704 PGERGSPGAQGLQGPRGLPGTPGTDG-PKGASGPAGPPGAQGPPGLQ-GMPGERGAAGIA 761
Query: 466 VPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPA-AGARRSSGAGTPRHSPTLPEPGGLR 524
P + P G + G GPP AGA G P P P G
Sbjct: 762 GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP------PGPAG-- 813
Query: 525 LELPLSRRGAPDPVGALSWRPPQGPVSFPG 554
RGAP G P GP F G
Sbjct: 814 ---SAGARGAPGERGETG---PPGPAGFAG 837
Score = 53.9 bits (128), Expect = 5e-07
Identities = 60/215 (27%), Positives = 75/215 (34%), Gaps = 40/215 (18%)
Query: 376 TPNQGRRP-PTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDP-GPASPYSGSGNGGF- 432
+P + P P GL G+ P+ AG+RG P P GP P +G GF
Sbjct: 313 SPGENGSPGPMGPRGLPGERGRTGPAGA----AGARGNDGQPGPAGPPGPVGPAGGPGFP 368
Query: 433 -AFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTV 491
A GA+G P G P+ A P +P PA G S
Sbjct: 369 GAPGAKGEAGPTGARGPEG-----------------AQGPRGEPGTPGSPGPA--GASGN 409
Query: 492 NGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGPVS 551
G G P GA+ S+GA +P P P RG P P GA P+G
Sbjct: 410 PGTDGIP--GAKGSAGAPGIAGAPGFPGP-----------RGPPGPQGATGPLGPKGQTG 456
Query: 552 FPGGAAFSTATSLPSSPAAAACAPLDSGASENSRK 586
PG A F P A A E ++
Sbjct: 457 EPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 491
Score = 49.7 bits (117), Expect = 9e-06
Identities = 57/211 (27%), Positives = 70/211 (33%), Gaps = 38/211 (18%)
Query: 2 PSSLGQP--DGGGGGGGGGGGVGAAGEDPGPGP--APPPEG-----AQEAAPAPRPPPEP 52
P + G P DG G G G GA G PGP +P P G + P P
Sbjct: 1040 PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1099
Query: 53 DDAAAALRLALDQLSALGLGGAGDTDEEGAAG-------------DGAAAAGGADGGAAP 99
A A + Q G AG+ E G G G + GA G A P
Sbjct: 1100 SGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGP 1159
Query: 100 E-------PVPPDGPEA--GAPPTL---APAVAPGSLPLLDPNASPPPPPPPRPSPPDV- 146
PV P G + G P + P G P +P PP PP P P +
Sbjct: 1160 SGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGID 1219
Query: 147 ---FAGFAPHPAALGPPTLLADQMSVIGSRK 174
FAG P P + + G R+
Sbjct: 1220 MSAFAGLGPREKGPDPLQYMRADQAAGGLRQ 1250
Score = 48.5 bits (114), Expect = 2e-05
Identities = 69/232 (29%), Positives = 78/232 (33%), Gaps = 47/232 (20%)
Query: 343 GAFTDAGPDSDFHANGTDVCLDLLGAAASLWAKTPNQGRRPPTATAGLRGDT-ALGAPSA 401
GA D GP G G S A P GR G RG+T A+GAP A
Sbjct: 1011 GASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP-PGRDGAAGVKGDRGETGAVGAPGA 1069
Query: 402 PEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLA 461
P G P PGPA P G+ G A GA+GP P G A A
Sbjct: 1070 P--------GPPG--SPGPAGPTGKQGDRGEA-GAQGPMGPSGPAG-------------A 1105
Query: 462 LDLTVPAA-----ATIWAPFERAAPLPAFSGCSTVNGAPGPPAA----GARRSSGAGTPR 512
+ P P ER L G + + G PGPP GA +G PR
Sbjct: 1106 RGIQGPQGPRGDKGEAGEPGERG--LKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1163
Query: 513 HSPTLPEPGG----------LRLELPLSRRGAPDPVGALSWRPPQGPVSFPG 554
P P G + P R G P G P GP PG
Sbjct: 1164 GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1215
Score = 46.6 bits (109), Expect = 7e-05
Identities = 158/660 (23%), Positives = 190/660 (28%), Gaps = 116/660 (17%)
Query: 10 GGGGGGGGGGGVGAAGEDPGPGPAPPP--------------EGAQ-EAAPAPRPPPEPDD 54
G G G G GA G D PGPA PP GA+ EA P PE
Sbjct: 330 GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ 389
Query: 55 AAAALRLALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPP- 113
G G TD A A A G A P P P GP+ P
Sbjct: 390 GPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 449
Query: 114 -----TLAPAVAPGSLPLLDPNASPPPPPP---PRPSPPDVFAGFAPHPAALGPPTLLAD 165
T P +A G P P P P P P+ + G P +GP
Sbjct: 450 GPKGQTGEPGIA-GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP------ 502
Query: 166 QMSVIGSRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFI 225
+ G R N P + +A G G + + A P R EP
Sbjct: 503 -IGPPGERGAPGNR----GFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP 557
Query: 226 ----VTGRKEDVEMAKREILSAAEHFSIIRATRSKAGGLPGAAQGPPNLPGQTTIQ-VRV 280
+TGR D + K G P A G PG Q R
Sbjct: 558 GARGLTGRPGDA------------------GPQGKVG--PSGAPGEDGRPGPPGPQGARG 597
Query: 281 PYRVVGLVVGPKGATIKRIQQRTHTYIVTPG----RDKEPVFAVTGMPENVDRAREEIEA 336
V+G GPKGA + + PG K+ G P A E E
Sbjct: 598 QPGVMGF-PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQ 656
Query: 337 HITLRTGAFTDAGPDSDFHANGTDVCLDLLGAAASLWAKTPNQGRRPPTATAGLRGDTAL 396
+G GP G + G A + P +G R G G L
Sbjct: 657 GAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGP-RGERGFPGERGSPGAQGL 715
Query: 397 GAPSAPEAFYAGSRGGPSVPDP----GPASPYSGSGNGGF-----------AFGAEGPGA 441
P G G P P GPA P G G G +G
Sbjct: 716 QGP-------RGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRG 768
Query: 442 PVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAP------ 495
VG P+ L + P A P P +G + GAP
Sbjct: 769 DVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP-PGPAGSAGARGAPGERGET 827
Query: 496 ---------GPPAA----GARRSSGAGTPRHSPTLPEP-GGLRLELPLSRRGAPDPVGAL 541
GPP A GA+ G + P P G P G P GA
Sbjct: 828 GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 887
Query: 542 SWRPPQGPVSFPG-----GAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAPAL 596
+ P G FPG G S P P + GA +S PP + P L
Sbjct: 888 GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS-GPPGRAGEPGL 946
Score = 46.6 bits (109), Expect = 7e-05
Identities = 48/166 (28%), Positives = 59/166 (35%), Gaps = 24/166 (14%)
Query: 8 PDGGGGGGGGGGGVGAAGEDPGPG-PAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQL 66
P G G G G VG G + PG P PP ++ R P A L
Sbjct: 892 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ---- 947
Query: 67 SALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPE---------PVPPDGPEAGAPPTLAP 117
G AG E+G GD + GA+G P+ +P E G P P
Sbjct: 948 -----GPAGPPGEKGEPGDDGPS--GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGP 1000
Query: 118 AVAPG--SLPLLDPNASPP-PPPPPRPSPPDVFAGFAPHPAALGPP 160
+ PG P + PP P PP + P G P A GPP
Sbjct: 1001 SGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 1046
Score = 46.2 bits (108), Expect = 9e-05
Identities = 47/162 (29%), Positives = 49/162 (30%), Gaps = 25/162 (15%)
Query: 8 PDGGGGGGGGGGGVGAAGEDPGPGP-APPPEGAQEAAPAPRPPPEPDDAAAALRLALDQL 66
P G G G G G GE PGP E P P PP P
Sbjct: 124 PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPP------------- 170
Query: 67 SALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAV------- 119
G G G AG AGGA G P+ P GP P AP
Sbjct: 171 ---GPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNP 227
Query: 120 -APGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPP 160
PG + P PP PP D AG GPP
Sbjct: 228 GEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 269
Score = 46.2 bits (108), Expect = 9e-05
Identities = 57/177 (32%), Positives = 67/177 (37%), Gaps = 42/177 (23%)
Query: 3 SSLGQPDGGGGGGGGGGGVGAAGEDPG---------PGPA-----------PPPEGAQEA 42
+ + P G G G G GA G+D G PGPA P P G+ A
Sbjct: 758 AGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGA 817
Query: 43 APAP-----RPPPEPDDAAAALRLALDQLSALGLGGA-GDTDEEGAAGD-GAAAAGGADG 95
AP PP P A A G GA G+ E G GD GA G G
Sbjct: 818 RGAPGERGETGPPGPAGFAG-------PPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSG 870
Query: 96 GAAPE-PVPPDGPEAGAPPTLAPAVA---PGSLPLLDP---NASPPPPPPPRPSPPD 145
P+ P GP+ GA P A PG+ + P N +P PP PP PS D
Sbjct: 871 APGPQGPTGVTGPK-GARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 926
Score = 41.2 bits (95), Expect = 0.003
Identities = 47/171 (27%), Positives = 58/171 (33%), Gaps = 23/171 (13%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPP-------EGAQEAAPAPRPPPEPDD 54
P+ P G G G G G +G GP PP E + R PP P
Sbjct: 214 PAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQG 273
Query: 55 A-----AAALRLALDQLSALGLGGA-GDTDEEGAAGD-GAAAAGGADGGAAPEPVPPDGP 107
A L GL GA G+ G G+ G+ G+ G P +P +
Sbjct: 274 ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERG 333
Query: 108 EAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALG 158
G PA A G+ + P P PP P P GF P A G
Sbjct: 334 RTG------PAGAAGA---RGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG 375
Score = 39.3 bits (90), Expect = 0.011
Identities = 52/185 (28%), Positives = 59/185 (31%), Gaps = 37/185 (20%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPP----EGAQEAAPAPRPPPEPDDAAA 57
PS P G G G G AGE GPA PP E + PP P A
Sbjct: 922 PSGKDGPKGA---RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG 978
Query: 58 ALRLALDQLSALGLGG----------AGDTDEEGAAG-DGAAAAGGADG--------GAA 98
Q +GL G G + E G G GA+ G G G A
Sbjct: 979 -------QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA 1031
Query: 99 PEPVPPDGPEAGAPPTLAPAVA----PGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHP 154
EP P A PP A G + +P PP P P+ P G
Sbjct: 1032 GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEA 1091
Query: 155 AALGP 159
A GP
Sbjct: 1092 GAQGP 1096
Score = 38.9 bits (89), Expect = 0.015
Identities = 73/258 (28%), Positives = 84/258 (32%), Gaps = 41/258 (15%)
Query: 349 GPDSDFHANGTDVCLDLLGAAASLW--AKTPNQGRRPPTATAGLRGDTALGAPSAPEAFY 406
GP A G GAA + N G P +G G S P
Sbjct: 882 GPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP--- 938
Query: 407 AGSRGGPSVPDP-GPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLT 465
G G P + P GP G+ G + GAEGP P G A +
Sbjct: 939 -GRAGEPGLQGPAGPPGEKGEPGDDGPS-GAEGPPGPQGLAGQRGI------------VG 984
Query: 466 VPAAATIWAPFERAAP-LPAFSGCSTVNGAPGPPAAGARRSSG-AGTPRHSPTLPEP--- 520
+P ER P LP SG GAPG A+G R G G P + EP
Sbjct: 985 LPGQRG-----ERGFPGLPGPSGEPGKQGAPG--ASGDRGPPGPVGPPGLTGPAGEPGRE 1037
Query: 521 GGLRLELPLSRRGAPDPVGALSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGA 580
G + P R GA G R G V PG A P SP A
Sbjct: 1038 GSPGADGPPGRDGA---AGVKGDRGETGAVGAPG------APGPPGSPGPAGPTGKQGDR 1088
Query: 581 SENSRKPPSASSAPALAR 598
E + P S PA AR
Sbjct: 1089 GEAGAQGPMGPSGPAGAR 1106
Score = 35.4 bits (80), Expect = 0.17
Identities = 61/219 (27%), Positives = 72/219 (32%), Gaps = 48/219 (21%)
Query: 379 QGRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEG 438
+G P AG RG +G P G RG P + PGP+ G G A G G
Sbjct: 968 EGPPGPQGLAGQRG--IVGLPGQ-----RGERGFPGL--PGPSGEPGKQGAPG-ASGDRG 1017
Query: 439 PGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAPGPP 498
P PVG LT PA A P G + V G G
Sbjct: 1018 PPGPVGPPG----------------LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRG-- 1059
Query: 499 AAGARRSSGAGTPRHSPTLPEPGGLRLEL----PLSRRGAPDPVGALSWRPPQGPVSFPG 554
GA + GA P SP P G + + G P GA + PQGP G
Sbjct: 1060 ETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKG 1119
Query: 555 GA------------AFSTATSLPSSPAAAACAPLDSGAS 581
A F+ LP P + D GAS
Sbjct: 1120 EAGEPGERGLKGHRGFTGLQGLPGPPGPSG----DQGAS 1154
Score = 30.8 bits (68), Expect = 4.1
Identities = 26/93 (27%), Positives = 30/93 (32%), Gaps = 14/93 (15%)
Query: 493 GAPGPPAA-GARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPD-------------PV 538
GAPGP G + G P P P P GL G D P+
Sbjct: 144 GAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPM 203
Query: 539 GALSWRPPQGPVSFPGGAAFSTATSLPSSPAAA 571
G + R P GP PG F P P +
Sbjct: 204 GPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVS 236
Score = 30.0 bits (66), Expect = 7.0
Identities = 52/193 (26%), Positives = 61/193 (31%), Gaps = 54/193 (27%)
Query: 380 GRRPPTATAGLRGDTA-LGAPSAPEAFYAGSRGGPSVP-DPGPASPYSGSGNGGFAFGAE 437
G + P G RGD G AP G G P P +PGP P
Sbjct: 123 GPQGPAGEQGPRGDRGDKGEKGAPGP--RGRDGEPGTPGNPGPPGP-------------P 167
Query: 438 GPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPF-ERAAPLPAFSGCSTVNGAPG 496
GP P G FD A + P R P PA GAPG
Sbjct: 168 GPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA--------GAPG 219
Query: 497 PPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVG-----ALSWRP------ 545
P G + + G EPG + P+ RG P P G + +P
Sbjct: 220 PQ--GFQGNPG-----------EPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGER 266
Query: 546 ----PQGPVSFPG 554
PQG FPG
Sbjct: 267 GPPGPQGARGFPG 279
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 58.2 bits (139), Expect = 2e-08
Identities = 148/570 (25%), Positives = 175/570 (30%), Gaps = 101/570 (17%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRL 61
P+ P G GG G G GA GE GP A PEGAQ P P P A A+
Sbjct: 283 PAGPPGPVGPAGGPGFPGAPGAKGE-AGPTGARGPEGAQGPRGEPGTPGSPGPAGAS--- 338
Query: 62 ALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPP------TL 115
G G GA G A A G A P P P GP+ P T
Sbjct: 339 ----------GNPGTDGIPGAKG-SAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTG 387
Query: 116 APAVAPGSLPLLDPNASPPPPPP---PRPSPPDVFAGFAPHPAALGPPTLLADQMSVIGS 172
P +A G P P P P P P+ + G P +GP + G
Sbjct: 388 EPGIA-GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP-------IGPPGE 439
Query: 173 RKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFI----VTG 228
R N P + +A G G + + A P R EP +TG
Sbjct: 440 RGAPGNR----GFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTG 495
Query: 229 RKEDVEMAKREILSAAEHFSIIRATRSKAGGLPGAAQGPPNLPGQTTIQ-VRVPYRVVGL 287
R D + K G P A G PG Q R V+G
Sbjct: 496 RPGDA------------------GPQGKVG--PSGAPGEDGRPGPPGPQGARGQPGVMGF 535
Query: 288 VVGPKGATIKRIQQRTHTYIVTPGRDKEPVFAVTGMPENVDRAREEIEAHITLRTGAFTD 347
GPKGA + PG+ E + G P ++ E G
Sbjct: 536 -PGPKGANGE------------PGKAGEK--GLPGAPGLRGLPGKDGETGAAGPPGPAGP 580
Query: 348 AGPDSDFHANGTDVCLDLLGAAASLWAKTPNQGRRP-PTATAGLRGDTALGAPSAPEAFY 406
AG + A G L G P +G +P G G L P F
Sbjct: 581 AGERGEQGAPGPSGFQGLPGPPG-----PPGEGGKPGDQGVPGEAGAPGLVGPRGERGF- 634
Query: 407 AGSRGGPSVPD-PGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLT 465
G RG P GP G G GA GP P G P G + A +
Sbjct: 635 PGERGSPGAQGLQGPRGLPGTPGTDG-PKGASGPAGPPGAQGPPGLQ-GMPGERGAAGIA 692
Query: 466 VPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPA-AGARRSSGAGTPRHSPTLPEPGGLR 524
P + P G + G GPP AGA G P P P G
Sbjct: 693 GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP------PGPAG-- 744
Query: 525 LELPLSRRGAPDPVGALSWRPPQGPVSFPG 554
RGAP G P GP F G
Sbjct: 745 ---SAGARGAPGERGETG---PPGPAGFAG 768
Score = 53.9 bits (128), Expect = 5e-07
Identities = 60/215 (27%), Positives = 75/215 (34%), Gaps = 40/215 (18%)
Query: 376 TPNQGRRP-PTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDP-GPASPYSGSGNGGF- 432
+P + P P GL G+ P+ AG+RG P P GP P +G GF
Sbjct: 244 SPGENGSPGPMGPRGLPGERGRTGPAGA----AGARGNDGQPGPAGPPGPVGPAGGPGFP 299
Query: 433 -AFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTV 491
A GA+G P G P+ A P +P PA G S
Sbjct: 300 GAPGAKGEAGPTGARGPEG-----------------AQGPRGEPGTPGSPGPA--GASGN 340
Query: 492 NGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGPVS 551
G G P GA+ S+GA +P P P RG P P GA P+G
Sbjct: 341 PGTDGIP--GAKGSAGAPGIAGAPGFPGP-----------RGPPGPQGATGPLGPKGQTG 387
Query: 552 FPGGAAFSTATSLPSSPAAAACAPLDSGASENSRK 586
PG A F P A A E ++
Sbjct: 388 EPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 422
Score = 49.7 bits (117), Expect = 9e-06
Identities = 57/211 (27%), Positives = 70/211 (33%), Gaps = 38/211 (18%)
Query: 2 PSSLGQP--DGGGGGGGGGGGVGAAGEDPGPGP--APPPEG-----AQEAAPAPRPPPEP 52
P + G P DG G G G GA G PGP +P P G + P P
Sbjct: 971 PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1030
Query: 53 DDAAAALRLALDQLSALGLGGAGDTDEEGAAG-------------DGAAAAGGADGGAAP 99
A A + Q G AG+ E G G G + GA G A P
Sbjct: 1031 SGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGP 1090
Query: 100 E-------PVPPDGPEA--GAPPTL---APAVAPGSLPLLDPNASPPPPPPPRPSPPDV- 146
PV P G + G P + P G P +P PP PP P P +
Sbjct: 1091 SGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGID 1150
Query: 147 ---FAGFAPHPAALGPPTLLADQMSVIGSRK 174
FAG P P + + G R+
Sbjct: 1151 MSAFAGLGPREKGPDPLQYMRADQAAGGLRQ 1181
Score = 48.5 bits (114), Expect = 2e-05
Identities = 69/232 (29%), Positives = 78/232 (33%), Gaps = 47/232 (20%)
Query: 343 GAFTDAGPDSDFHANGTDVCLDLLGAAASLWAKTPNQGRRPPTATAGLRGDT-ALGAPSA 401
GA D GP G G S A P GR G RG+T A+GAP A
Sbjct: 942 GASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP-PGRDGAAGVKGDRGETGAVGAPGA 1000
Query: 402 PEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLA 461
P G P PGPA P G+ G A GA+GP P G A A
Sbjct: 1001 P--------GPPG--SPGPAGPTGKQGDRGEA-GAQGPMGPSGPAG-------------A 1036
Query: 462 LDLTVPAA-----ATIWAPFERAAPLPAFSGCSTVNGAPGPPAA----GARRSSGAGTPR 512
+ P P ER L G + + G PGPP GA +G PR
Sbjct: 1037 RGIQGPQGPRGDKGEAGEPGERG--LKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1094
Query: 513 HSPTLPEPGG----------LRLELPLSRRGAPDPVGALSWRPPQGPVSFPG 554
P P G + P R G P G P GP PG
Sbjct: 1095 GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1146
Score = 46.6 bits (109), Expect = 7e-05
Identities = 158/660 (23%), Positives = 190/660 (28%), Gaps = 116/660 (17%)
Query: 10 GGGGGGGGGGGVGAAGEDPGPGPAPPP--------------EGAQ-EAAPAPRPPPEPDD 54
G G G G GA G D PGPA PP GA+ EA P PE
Sbjct: 261 GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ 320
Query: 55 AAAALRLALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPP- 113
G G TD A A A G A P P P GP+ P
Sbjct: 321 GPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 380
Query: 114 -----TLAPAVAPGSLPLLDPNASPPPPPP---PRPSPPDVFAGFAPHPAALGPPTLLAD 165
T P +A G P P P P P P+ + G P +GP
Sbjct: 381 GPKGQTGEPGIA-GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP------ 433
Query: 166 QMSVIGSRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFI 225
+ G R N P + +A G G + + A P R EP
Sbjct: 434 -IGPPGERGAPGNR----GFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP 488
Query: 226 ----VTGRKEDVEMAKREILSAAEHFSIIRATRSKAGGLPGAAQGPPNLPGQTTIQ-VRV 280
+TGR D + K G P A G PG Q R
Sbjct: 489 GARGLTGRPGDA------------------GPQGKVG--PSGAPGEDGRPGPPGPQGARG 528
Query: 281 PYRVVGLVVGPKGATIKRIQQRTHTYIVTPG----RDKEPVFAVTGMPENVDRAREEIEA 336
V+G GPKGA + + PG K+ G P A E E
Sbjct: 529 QPGVMGF-PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQ 587
Query: 337 HITLRTGAFTDAGPDSDFHANGTDVCLDLLGAAASLWAKTPNQGRRPPTATAGLRGDTAL 396
+G GP G + G A + P +G R G G L
Sbjct: 588 GAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGP-RGERGFPGERGSPGAQGL 646
Query: 397 GAPSAPEAFYAGSRGGPSVPDP----GPASPYSGSGNGGF-----------AFGAEGPGA 441
P G G P P GPA P G G G +G
Sbjct: 647 QGP-------RGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRG 699
Query: 442 PVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAP------ 495
VG P+ L + P A P P +G + GAP
Sbjct: 700 DVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP-PGPAGSAGARGAPGERGET 758
Query: 496 ---------GPPAA----GARRSSGAGTPRHSPTLPEP-GGLRLELPLSRRGAPDPVGAL 541
GPP A GA+ G + P P G P G P GA
Sbjct: 759 GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 818
Query: 542 SWRPPQGPVSFPG-----GAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAPAL 596
+ P G FPG G S P P + GA +S PP + P L
Sbjct: 819 GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS-GPPGRAGEPGL 877
Score = 46.6 bits (109), Expect = 7e-05
Identities = 48/166 (28%), Positives = 59/166 (35%), Gaps = 24/166 (14%)
Query: 8 PDGGGGGGGGGGGVGAAGEDPGPG-PAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQL 66
P G G G G VG G + PG P PP ++ R P A L
Sbjct: 823 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ---- 878
Query: 67 SALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPE---------PVPPDGPEAGAPPTLAP 117
G AG E+G GD + GA+G P+ +P E G P P
Sbjct: 879 -----GPAGPPGEKGEPGDDGPS--GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGP 931
Query: 118 AVAPG--SLPLLDPNASPP-PPPPPRPSPPDVFAGFAPHPAALGPP 160
+ PG P + PP P PP + P G P A GPP
Sbjct: 932 SGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 977
Score = 46.2 bits (108), Expect = 9e-05
Identities = 47/162 (29%), Positives = 49/162 (30%), Gaps = 25/162 (15%)
Query: 8 PDGGGGGGGGGGGVGAAGEDPGPGP-APPPEGAQEAAPAPRPPPEPDDAAAALRLALDQL 66
P G G G G G GE PGP E P P PP P
Sbjct: 55 PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPP------------- 101
Query: 67 SALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAV------- 119
G G G AG AGGA G P+ P GP P AP
Sbjct: 102 ---GPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNP 158
Query: 120 -APGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPP 160
PG + P PP PP D AG GPP
Sbjct: 159 GEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 200
Score = 46.2 bits (108), Expect = 9e-05
Identities = 49/153 (32%), Positives = 57/153 (37%), Gaps = 10/153 (6%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRL 61
P DGG G G G G AG + G PP A A P +
Sbjct: 706 PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG 765
Query: 62 ALDQLSALGLGGA-GDTDEEGAAGD-GAAAAGGADGGAAPE-PVPPDGPEAGAPPTLAPA 118
A G GA G+ E G GD GA G G P+ P GP+ GA P
Sbjct: 766 FAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPK-GARGAQGPP 824
Query: 119 VA---PGSLPLLDP---NASPPPPPPPRPSPPD 145
A PG+ + P N +P PP PP PS D
Sbjct: 825 GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 857
Score = 41.2 bits (95), Expect = 0.003
Identities = 47/171 (27%), Positives = 58/171 (33%), Gaps = 23/171 (13%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPP-------EGAQEAAPAPRPPPEPDD 54
P+ P G G G G G +G GP PP E + R PP P
Sbjct: 145 PAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQG 204
Query: 55 A-----AAALRLALDQLSALGLGGA-GDTDEEGAAGD-GAAAAGGADGGAAPEPVPPDGP 107
A L GL GA G+ G G+ G+ G+ G P +P +
Sbjct: 205 ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERG 264
Query: 108 EAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALG 158
G PA A G+ + P P PP P P GF P A G
Sbjct: 265 RTG------PAGAAGA---RGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG 306
Score = 39.3 bits (90), Expect = 0.011
Identities = 52/185 (28%), Positives = 59/185 (31%), Gaps = 37/185 (20%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPP----EGAQEAAPAPRPPPEPDDAAA 57
PS P G G G G AGE GPA PP E + PP P A
Sbjct: 853 PSGKDGPKGA---RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG 909
Query: 58 ALRLALDQLSALGLGG----------AGDTDEEGAAG-DGAAAAGGADG--------GAA 98
Q +GL G G + E G G GA+ G G G A
Sbjct: 910 -------QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA 962
Query: 99 PEPVPPDGPEAGAPPTLAPAVA----PGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHP 154
EP P A PP A G + +P PP P P+ P G
Sbjct: 963 GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEA 1022
Query: 155 AALGP 159
A GP
Sbjct: 1023 GAQGP 1027
Score = 38.9 bits (89), Expect = 0.015
Identities = 73/258 (28%), Positives = 84/258 (32%), Gaps = 41/258 (15%)
Query: 349 GPDSDFHANGTDVCLDLLGAAASLW--AKTPNQGRRPPTATAGLRGDTALGAPSAPEAFY 406
GP A G GAA + N G P +G G S P
Sbjct: 813 GPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP--- 869
Query: 407 AGSRGGPSVPDP-GPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLT 465
G G P + P GP G+ G + GAEGP P G A +
Sbjct: 870 -GRAGEPGLQGPAGPPGEKGEPGDDGPS-GAEGPPGPQGLAGQRGI------------VG 915
Query: 466 VPAAATIWAPFERAAP-LPAFSGCSTVNGAPGPPAAGARRSSG-AGTPRHSPTLPEP--- 520
+P ER P LP SG GAPG A+G R G G P + EP
Sbjct: 916 LPGQRG-----ERGFPGLPGPSGEPGKQGAPG--ASGDRGPPGPVGPPGLTGPAGEPGRE 968
Query: 521 GGLRLELPLSRRGAPDPVGALSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGA 580
G + P R GA G R G V PG A P SP A
Sbjct: 969 GSPGADGPPGRDGA---AGVKGDRGETGAVGAPG------APGPPGSPGPAGPTGKQGDR 1019
Query: 581 SENSRKPPSASSAPALAR 598
E + P S PA AR
Sbjct: 1020 GEAGAQGPMGPSGPAGAR 1037
Score = 35.4 bits (80), Expect = 0.17
Identities = 61/219 (27%), Positives = 72/219 (32%), Gaps = 48/219 (21%)
Query: 379 QGRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEG 438
+G P AG RG +G P G RG P + PGP+ G G A G G
Sbjct: 899 EGPPGPQGLAGQRG--IVGLPGQ-----RGERGFPGL--PGPSGEPGKQGAPG-ASGDRG 948
Query: 439 PGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAPGPP 498
P PVG LT PA A P G + V G G
Sbjct: 949 PPGPVGPPG----------------LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRG-- 990
Query: 499 AAGARRSSGAGTPRHSPTLPEPGGLRLEL----PLSRRGAPDPVGALSWRPPQGPVSFPG 554
GA + GA P SP P G + + G P GA + PQGP G
Sbjct: 991 ETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKG 1050
Query: 555 GA------------AFSTATSLPSSPAAAACAPLDSGAS 581
A F+ LP P + D GAS
Sbjct: 1051 EAGEPGERGLKGHRGFTGLQGLPGPPGPSG----DQGAS 1085
Score = 30.8 bits (68), Expect = 4.1
Identities = 26/93 (27%), Positives = 30/93 (32%), Gaps = 14/93 (15%)
Query: 493 GAPGPPAA-GARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPD-------------PV 538
GAPGP G + G P P P P GL G D P+
Sbjct: 75 GAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPM 134
Query: 539 GALSWRPPQGPVSFPGGAAFSTATSLPSSPAAA 571
G + R P GP PG F P P +
Sbjct: 135 GPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVS 167
Score = 30.0 bits (66), Expect = 7.0
Identities = 52/193 (26%), Positives = 61/193 (31%), Gaps = 54/193 (27%)
Query: 380 GRRPPTATAGLRGDTA-LGAPSAPEAFYAGSRGGPSVP-DPGPASPYSGSGNGGFAFGAE 437
G + P G RGD G AP G G P P +PGP P
Sbjct: 54 GPQGPAGEQGPRGDRGDKGEKGAPGP--RGRDGEPGTPGNPGPPGP-------------P 98
Query: 438 GPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPF-ERAAPLPAFSGCSTVNGAPG 496
GP P G FD A + P R P PA GAPG
Sbjct: 99 GPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA--------GAPG 150
Query: 497 PPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVG-----ALSWRP------ 545
P G + + G EPG + P+ RG P P G + +P
Sbjct: 151 PQ--GFQGNPG-----------EPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGER 197
Query: 546 ----PQGPVSFPG 554
PQG FPG
Sbjct: 198 GPPGPQGARGFPG 210
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 58.2 bits (139), Expect = 2e-08
Identities = 96/362 (26%), Positives = 117/362 (32%), Gaps = 92/362 (25%)
Query: 2 PSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAP-----RPPPE----- 51
P + +P G GGGG PGP P A PAP RPPPE
Sbjct: 83 PGAAPEPPPAGRARPGGGG------PQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGS 136
Query: 52 --PDDAAAALRLALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEA 109
P AAAA+ + A AG AG G G G P P P GP
Sbjct: 137 CAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGP--GPGPGPGKPAGP-- 192
Query: 110 GAPPTL-------------APAVA------PGSLPLLDPNA------SPP------PPPP 138
GA TL APAV+ LPL P A +PP PP P
Sbjct: 193 GAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAP 252
Query: 139 PRPSPPDVFAGFAP-------------------HPAALGPPTLLADQMSVIGSRKKSVNM 179
PSPP A AP HPA GPPT ++
Sbjct: 253 AAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPA--GPPTAAPAVPPPAAAQNGGSAG 310
Query: 180 TECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFIVTGRKEDVEMAKRE 239
P P++ A + G+ G A V+ E P +V +
Sbjct: 311 AAPAPAPAAGGPAGVSGQPGPGAAAAAPAPG------VKAESPKRVVQAAPPAAQTLAAS 364
Query: 240 ILSAAEHFSIIRATRSKAGGLPGAAQGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRI 299
++ +I T G LP A PP PG T GL G GA + +
Sbjct: 365 GPASTAASMVIGPTMQ--GALPSPAAVPPPAPGTPT----------GLPKGAAGAVTQSL 412
Query: 300 QQ 301
+
Sbjct: 413 SR 414
Score = 55.5 bits (132), Expect = 2e-07
Identities = 47/154 (30%), Positives = 49/154 (31%), Gaps = 24/154 (15%)
Query: 6 GQPDGGGGGGGGGGGVGAAGEDPGPGPA----PPPEGAQEAAPA----PRPPPEPDDAAA 57
G P G G G GA G P P PA P G Q P P P P AA
Sbjct: 65 GSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAA 124
Query: 58 ALRLALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAP 117
LR EG+AG A A A PEP P + P LA
Sbjct: 125 KLR----------------PPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAA 168
Query: 118 AVAPGSLPLLDPNASPPPPPPPRPSPPDVFAGFA 151
PG P P P P P P G A
Sbjct: 169 RAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSA 202
Score = 45.1 bits (105), Expect = 2e-04
Identities = 58/197 (29%), Positives = 74/197 (37%), Gaps = 41/197 (20%)
Query: 392 GDTALGAPSAPEAFYAGSRGGPSV-PDPGPASPYSGSGNGGFAFGAEGPGAPVG--TAAP 448
G A AP+AP A + P+ P P P +P A A PG P G TAAP
Sbjct: 245 GAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAP---------ATLARPPGHPAGPPTAAP 295
Query: 449 DDCDFGFDFDFLALDLTVPAAATIWAPFERA-APLPAFSGCSTVNGAPGPPAAGARRSSG 507
+ PAAA A AP PA G + V+G PGP AA A + G
Sbjct: 296 A--------------VPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPG 341
Query: 508 A----------GTPRHSPTLPEPG----GLRLELPLSRRGAPDPVGALSWRPPQGPVSFP 553
P + TL G + + + +GA A+ P P P
Sbjct: 342 VKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLP 401
Query: 554 GGAAFSTATSLPSSPAA 570
GAA + SL +P A
Sbjct: 402 KGAAGAVTQSLSRTPTA 418
Score = 44.7 bits (104), Expect = 3e-04
Identities = 68/263 (25%), Positives = 83/263 (31%), Gaps = 45/263 (17%)
Query: 381 RRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDPGPASPYS----------GSGNG 430
R PP +AG AP A GP GPA P G G G
Sbjct: 127 RPPPEGSAG---------SCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPG 177
Query: 431 GFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCST 490
GPG P G A + G + PA + + PLP + T
Sbjct: 178 PGPGPGPGPGKPAGPGAAQTLN-GSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGT 236
Query: 491 V--------------NGAPGPPAAGARRSSGAGTPRHSP---TLPEPGGLRLELPLSRRG 533
V AP PPAA A + A P P TL P G P +
Sbjct: 237 VIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPA 296
Query: 534 APDPVGAL---SWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSA 590
P P A S P GG A S P AAA AP +E+ ++ A
Sbjct: 297 VPPPAAAQNGGSAGAAPAPAPAAGGPA---GVSGQPGPGAAAAAPAPGVKAESPKRVVQA 353
Query: 591 SSAPALARECVVCAEGEVMAALV 613
AP A+ A++V
Sbjct: 354 --APPAAQTLAASGPASTAASMV 374
Score = 42.7 bits (99), Expect = 0.001
Identities = 38/112 (33%), Positives = 41/112 (36%), Gaps = 33/112 (29%)
Query: 81 GAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPR 140
GAAG G AA GAAPEP P A PG P P PP
Sbjct: 69 GAAGAGPAAPAEGAPGAAPEPPP------------AGRARPGG-------GGPQRPGPPS 109
Query: 141 PSPPDVFAGFAPHPAALGPPTLLADQMSVIGSRKKSVNMTECVPVPSSEHVA 192
P P V AG AP A L PP + C PVP++ VA
Sbjct: 110 PRRPLVPAGPAPPAAKLRPP--------------PEGSAGSCAPVPAAAAVA 147
Score = 40.8 bits (94), Expect = 0.004
Identities = 61/219 (27%), Positives = 78/219 (35%), Gaps = 21/219 (9%)
Query: 384 PTATAGLRGDTAL---GAPSAPEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGPG 440
P A L G AL +AP + +P P PA+P + F GA P
Sbjct: 192 PGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFV-GAAAPP 250
Query: 441 APVGTAAPDDCDFGFDFDFLALDLTVPAAATIW---APFERAAPLPAFSGCSTVNGAPGP 497
AP + P A PAAA AP A P +G T A P
Sbjct: 251 APAAPSPP-----------AAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPP 299
Query: 498 PAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGPVSFPGGAA 557
PAA S P +P P G+ + P A P + P+ V AA
Sbjct: 300 PAAAQNGGSAGAAPAPAPAAGGPAGVSGQ-PGPGAAAAAPAPGVKAESPKRVVQAAPPAA 358
Query: 558 FSTATSLPSSPAAA-ACAPLDSGASEN-SRKPPSASSAP 594
+ A S P+S AA+ P GA + + PP A P
Sbjct: 359 QTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTP 397
Score = 37.7 bits (86), Expect = 0.033
Identities = 61/238 (25%), Positives = 76/238 (31%), Gaps = 33/238 (13%)
Query: 392 GDTALGAPSAPEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGPGAPVGTA--APD 449
G A A + P A G+ G + P+P PA G G G P P+ A AP
Sbjct: 65 GSPAGAAGAGPAAPAEGAPG--AAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPP 122
Query: 450 DCDFGFDFDFLALDLT-VPAAATIWA---PFERAAPLPAFSGCSTVNGAPGP-PAAGARR 504
+ A VPAAA + A P PA PGP P G
Sbjct: 123 AAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGP 182
Query: 505 SSGAGTP-----------------RHSPTLPE----PGGLRLELPLSRRGAPDPVGALSW 543
G G P H P G LPL + AP G +
Sbjct: 183 GPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAP---GTVIQ 239
Query: 544 RPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAPALARECV 601
PP + P A + + P+ A AA P A +PP + P A V
Sbjct: 240 TPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAV 297
Score = 32.7 bits (73), Expect = 1.1
Identities = 35/121 (28%), Positives = 47/121 (38%), Gaps = 10/121 (8%)
Query: 475 PFERAAPLPAFSGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGA 534
P RAA A G V+G+P A + G P +P P G R G
Sbjct: 48 PEVRAAAAGAL-GNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRAR-----PGGGG 101
Query: 535 PDPVGALSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAP 594
P G S R P P G A + P +A +CAP+ + A+ + P A + P
Sbjct: 102 PQRPGPPSPRRPLVPA---GPAPPAAKLRPPPEGSAGSCAPVPAAAAV-AAGPEPAPAGP 157
Query: 595 A 595
A
Sbjct: 158 A 158
>gi|239749482 PREDICTED: hypothetical protein [Homo sapiens]
Length = 195
Score = 57.8 bits (138), Expect = 3e-08
Identities = 58/159 (36%), Positives = 63/159 (39%), Gaps = 32/159 (20%)
Query: 10 GGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRP--PPEPDDAAAALRLALDQLS 67
GGG G GVG G PGPA G PAP PP P + AA R LS
Sbjct: 16 GGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAAR-----LS 70
Query: 68 ALGLGGAGDTDEEGAAGDGAAAAG--GADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLP 125
AL AA + G G GG P+PP GAP A A +PG LP
Sbjct: 71 AL-----------AAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA-APSPGPLP 118
Query: 126 LLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPPTLLA 164
+ P PPPRPS P PH L P L A
Sbjct: 119 ------ARPSSPPPRPSLPS-----GPHRPVLPPSALAA 146
Score = 30.0 bits (66), Expect = 7.0
Identities = 38/137 (27%), Positives = 50/137 (36%), Gaps = 32/137 (23%)
Query: 466 VPAAATIWAPFERAAPLPAFSGCSTVNGAPGP---PAAGARRSSGAGTPRHSPTLPEPGG 522
+P A + A + P PA + P P PAA + A PR P+ GG
Sbjct: 35 LPGPALVVAGLDGIRPAPAAAH------PPAPRERPAAARLSALAAAQPRRRSPGPQGGG 88
Query: 523 ---LRLELP--LSRRGAPDPVGALSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLD 577
+ LP L RGAP A+ P GP LP+ P++ P
Sbjct: 89 GGDIASPLPPALQPRGAP----AVPAAPSPGP--------------LPARPSSPPPRPSL 130
Query: 578 SGASENSRKPPSASSAP 594
PPSA +AP
Sbjct: 131 PSGPHRPVLPPSALAAP 147
>gi|239743620 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 57.8 bits (138), Expect = 3e-08
Identities = 58/159 (36%), Positives = 63/159 (39%), Gaps = 32/159 (20%)
Query: 10 GGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRP--PPEPDDAAAALRLALDQLS 67
GGG G GVG G PGPA G PAP PP P + AA R LS
Sbjct: 16 GGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAAR-----LS 70
Query: 68 ALGLGGAGDTDEEGAAGDGAAAAG--GADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLP 125
AL AA + G G GG P+PP GAP A A +PG LP
Sbjct: 71 AL-----------AAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA-APSPGPLP 118
Query: 126 LLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPPTLLA 164
+ P PPPRPS P PH L P L A
Sbjct: 119 ------ARPSSPPPRPSLPS-----GPHRPVLPPSALAA 146
Score = 30.0 bits (66), Expect = 7.0
Identities = 38/137 (27%), Positives = 50/137 (36%), Gaps = 32/137 (23%)
Query: 466 VPAAATIWAPFERAAPLPAFSGCSTVNGAPGP---PAAGARRSSGAGTPRHSPTLPEPGG 522
+P A + A + P PA + P P PAA + A PR P+ GG
Sbjct: 35 LPGPALVVAGLDGIRPAPAAAH------PPAPRERPAAARLSALAAAQPRRRSPGPQGGG 88
Query: 523 ---LRLELP--LSRRGAPDPVGALSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLD 577
+ LP L RGAP A+ P GP LP+ P++ P
Sbjct: 89 GGDIASPLPPALQPRGAP----AVPAAPSPGP--------------LPARPSSPPPRPSL 130
Query: 578 SGASENSRKPPSASSAP 594
PPSA +AP
Sbjct: 131 PSGPHRPVLPPSALAAP 147
>gi|74027251 tripartite motif-containing 33 protein isoform beta
[Homo sapiens]
Length = 1110
Score = 57.8 bits (138), Expect = 3e-08
Identities = 47/135 (34%), Positives = 59/135 (43%), Gaps = 18/135 (13%)
Query: 5 LGQPDGGGGGGGGGGGVGAAGEDPGP-GPAPPPEGAQEAAPAPRPPPEPDDAAAALRLAL 63
+ + GGG GGGG G+A G GPA AQEA P ++ R
Sbjct: 1 MAENKGGGEAESGGGGSGSAPVTAGAAGPA-----AQEAEPPLTAVLVEEEEEEGGRAGA 55
Query: 64 DQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGS 123
+ GGA D+ G A AA++G A ++P G GA T PA AP S
Sbjct: 56 E-------GGAAGPDDGGVA---AASSGSAQAASSPAASVGTGVAGGAVST--PAPAPAS 103
Query: 124 LPLLDPNASPPPPPP 138
P P+A PPP PP
Sbjct: 104 APAPGPSAGPPPGPP 118
Score = 35.8 bits (81), Expect = 0.13
Identities = 36/131 (27%), Positives = 49/131 (37%), Gaps = 34/131 (25%)
Query: 548 GPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAP------------A 595
GP AA S + SSPAA+ + GA P+++ AP +
Sbjct: 61 GPDDGGVAAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPAS 120
Query: 596 LARECVVCAEG-----EVMAALVPCGHNLFCMDC--------AVRICGKSEPE------- 635
L C VC + E L+PC H+ FC+ C +V I G S +
Sbjct: 121 LLDTCAVCQQSLQSRREAEPKLLPCLHS-FCLRCLPEPERQLSVPIPGGSNGDIQQVGVI 179
Query: 636 -CPACRTPATQ 645
CP CR Q
Sbjct: 180 RCPVCRQECRQ 190
Score = 33.1 bits (74), Expect = 0.82
Identities = 41/150 (27%), Positives = 52/150 (34%), Gaps = 33/150 (22%)
Query: 407 AGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTV 466
AG+ GG + PD G + + + G A A P A VGT A+
Sbjct: 53 AGAEGGAAGPDDGGVA----AASSGSAQAASSPAASVGTGVAGG----------AVSTPA 98
Query: 467 PAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRLE 526
PA A+ AP A P PGPPA+ + S EP L
Sbjct: 99 PAPASAPAPGPSAGP------------PPGPPASLLDTCAVCQQSLQSRREAEPKLLPCL 146
Query: 527 LPLSRRGAPDPVGALSWRPPQGPVSFPGGA 556
R P+P LS V PGG+
Sbjct: 147 HSFCLRCLPEPERQLS-------VPIPGGS 169
Score = 32.7 bits (73), Expect = 1.1
Identities = 17/47 (36%), Positives = 19/47 (40%)
Query: 17 GGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLAL 63
G G G A P P PA P A P P PP D A + +L
Sbjct: 86 GTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSL 132
>gi|74027249 tripartite motif-containing 33 protein isoform alpha
[Homo sapiens]
Length = 1127
Score = 57.8 bits (138), Expect = 3e-08
Identities = 47/135 (34%), Positives = 59/135 (43%), Gaps = 18/135 (13%)
Query: 5 LGQPDGGGGGGGGGGGVGAAGEDPGP-GPAPPPEGAQEAAPAPRPPPEPDDAAAALRLAL 63
+ + GGG GGGG G+A G GPA AQEA P ++ R
Sbjct: 1 MAENKGGGEAESGGGGSGSAPVTAGAAGPA-----AQEAEPPLTAVLVEEEEEEGGRAGA 55
Query: 64 DQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGS 123
+ GGA D+ G A AA++G A ++P G GA T PA AP S
Sbjct: 56 E-------GGAAGPDDGGVA---AASSGSAQAASSPAASVGTGVAGGAVST--PAPAPAS 103
Query: 124 LPLLDPNASPPPPPP 138
P P+A PPP PP
Sbjct: 104 APAPGPSAGPPPGPP 118
Score = 35.8 bits (81), Expect = 0.13
Identities = 36/131 (27%), Positives = 49/131 (37%), Gaps = 34/131 (25%)
Query: 548 GPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAP------------A 595
GP AA S + SSPAA+ + GA P+++ AP +
Sbjct: 61 GPDDGGVAAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPAS 120
Query: 596 LARECVVCAEG-----EVMAALVPCGHNLFCMDC--------AVRICGKSEPE------- 635
L C VC + E L+PC H+ FC+ C +V I G S +
Sbjct: 121 LLDTCAVCQQSLQSRREAEPKLLPCLHS-FCLRCLPEPERQLSVPIPGGSNGDIQQVGVI 179
Query: 636 -CPACRTPATQ 645
CP CR Q
Sbjct: 180 RCPVCRQECRQ 190
Score = 33.1 bits (74), Expect = 0.82
Identities = 41/150 (27%), Positives = 52/150 (34%), Gaps = 33/150 (22%)
Query: 407 AGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLALDLTV 466
AG+ GG + PD G + + + G A A P A VGT A+
Sbjct: 53 AGAEGGAAGPDDGGVA----AASSGSAQAASSPAASVGTGVAGG----------AVSTPA 98
Query: 467 PAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRLE 526
PA A+ AP A P PGPPA+ + S EP L
Sbjct: 99 PAPASAPAPGPSAGP------------PPGPPASLLDTCAVCQQSLQSRREAEPKLLPCL 146
Query: 527 LPLSRRGAPDPVGALSWRPPQGPVSFPGGA 556
R P+P LS V PGG+
Sbjct: 147 HSFCLRCLPEPERQLS-------VPIPGGS 169
Score = 32.7 bits (73), Expect = 1.1
Identities = 17/47 (36%), Positives = 19/47 (40%)
Query: 17 GGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLAL 63
G G G A P P PA P A P P PP D A + +L
Sbjct: 86 GTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSL 132
>gi|73476377 LBXCOR1 homolog [Homo sapiens]
Length = 921
Score = 57.8 bits (138), Expect = 3e-08
Identities = 54/170 (31%), Positives = 63/170 (37%), Gaps = 33/170 (19%)
Query: 6 GQPDGGGGGGGGGGGVGAAGEDPGPGPA--PPPEGAQEAAPA----PRPPPEPDDAAAAL 59
G+P GG G G GGGG G G GPG + PP GA A +P DAAA
Sbjct: 373 GEPKGGPGTGSGGGGAGTGGGAGGPGASHLPPGAGAGPGGGAMFWGHQPSGAAKDAAAVA 432
Query: 60 RL---------------ALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPP 104
A L A + AA AAAA A + P P
Sbjct: 433 AAAAAATVYPTFPMFWPAAGSLPVPSYPAAQSQAKAVAAAVAAAAAAAAAAAGSGAPEPL 492
Query: 105 DGPE------AGAPPTLAPAVAPGSL------PLLDPNASPPPPPPPRPS 142
DG E GA A++ G L L P +P PPPPP P+
Sbjct: 493 DGAEPAKESGLGAEERCPSALSRGPLDEDGTDEALPPPLAPLPPPPPPPA 542
Score = 38.1 bits (87), Expect = 0.026
Identities = 38/113 (33%), Positives = 42/113 (37%), Gaps = 8/113 (7%)
Query: 5 LGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEG---AQEAAPAPRPPPEPDDAAAALRL 61
LG G G G GG G AG P P +G Q+ P P P A L
Sbjct: 304 LGLATGASGPAGPGGPGGGAGVRSYPVIPVPSKGFGLLQKLPPPLFPHPYGFPTAFGLCP 363
Query: 62 ALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPD---GPEAGA 111
D LG G G+ G GA GGA GG +PP GP GA
Sbjct: 364 KKDD-PVLGAGEPKGGPGTGSGGGGAGTGGGA-GGPGASHLPPGAGAGPGGGA 414
Score = 36.6 bits (83), Expect = 0.075
Identities = 61/243 (25%), Positives = 77/243 (31%), Gaps = 39/243 (16%)
Query: 388 AGLRGDTALGAPSAP-----EAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGPGAP 442
A G T GA AP ++ G P P P P G G A G GPG P
Sbjct: 260 AMFNGGTRCGAEMAPGPPPHKSLRCGEDEAAGPPGPPPPHPQRGLGLATGASGPAGPGGP 319
Query: 443 VGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAP--LPAFSGCSTVNG------- 493
G A +P + + ++ P P G T G
Sbjct: 320 GGGAGVRSYP------------VIPVPSKGFGLLQKLPPPLFPHPYGFPTAFGLCPKKDD 367
Query: 494 ---APGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSW-RPPQGP 549
G P G SG G PG L GA GA+ W P G
Sbjct: 368 PVLGAGEPKGGPGTGSGGGGAGTGGGAGGPGASHLP---PGAGAGPGGGAMFWGHQPSGA 424
Query: 550 VSFPG--GAAFSTATSLPSSP---AAAACAPLDS-GASENSRKPPSASSAPALARECVVC 603
AA + AT P+ P AA P+ S A+++ K +A+ A A A
Sbjct: 425 AKDAAAVAAAAAAATVYPTFPMFWPAAGSLPVPSYPAAQSQAKAVAAAVAAAAAAAAAAA 484
Query: 604 AEG 606
G
Sbjct: 485 GSG 487
Score = 31.6 bits (70), Expect = 2.4
Identities = 48/159 (30%), Positives = 58/159 (36%), Gaps = 23/159 (14%)
Query: 10 GGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPR----PPPEPDDAAAALRLALDQ 65
GGG G G +A GPA P+G +P PR PPP A R A
Sbjct: 642 GGGPDGEQPTGPPSATSSGADGPANSPDG---GSPRPRRRLGPPP-------AGRPAFGD 691
Query: 66 LSALGLGGAGD-TDEEGAAGDGAAAAGGADGGAAPEPV-PPDGPE--AGAPPTLAPAVA- 120
L+A L + + G G G GG AP V P+ E A L PA +
Sbjct: 692 LAAEDLVRRPERSPPSGGGGYELREPCGPLGGPAPAKVFAPERDEHVKSAAVALGPAASY 751
Query: 121 ----PGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPHPA 155
P + N SP R S PD + P PA
Sbjct: 752 VCTPEAHEPDKEDNHSPADDLETRKSYPDQRSISQPSPA 790
Score = 31.2 bits (69), Expect = 3.1
Identities = 31/111 (27%), Positives = 45/111 (40%), Gaps = 15/111 (13%)
Query: 407 AGSRGGPSVPDPGPASPYSGSGNGGFA--FGAEGPGAPVGTAAPDDCDFGFDFDFLALDL 464
AG+ GG P P +G+G GG A +G + GA AA A
Sbjct: 388 AGTGGGAGGPGASHLPPGAGAGPGGGAMFWGHQPSGAAKDAAA---------VAAAAAAA 438
Query: 465 TVPAAATIWAPFERAAPLPAF----SGCSTVNGAPGPPAAGARRSSGAGTP 511
TV ++ P + P+P++ S V A AA A ++G+G P
Sbjct: 439 TVYPTFPMFWPAAGSLPVPSYPAAQSQAKAVAAAVAAAAAAAAAAAGSGAP 489
Score = 30.4 bits (67), Expect = 5.3
Identities = 39/128 (30%), Positives = 43/128 (33%), Gaps = 22/128 (17%)
Query: 69 LGLGGAGDTDEEGAAGDGAAAA--GGADGGA--APEPVPPDGPEAGAPPTLAPAVAPGSL 124
L L TDE A + A GG GA AP P P G
Sbjct: 240 LKLSDKSATDELSHAWEDVKAMFNGGTRCGAEMAPGPPPHKSLRCGE------------- 286
Query: 125 PLLDPNASPPPPPPPRPSPPDVFAGFAPHPAALGPPTLLADQMS--VIGSRKKSVNMTEC 182
D A PP PPPP P A A PA G P A S VI K + +
Sbjct: 287 ---DEAAGPPGPPPPHPQRGLGLATGASGPAGPGGPGGGAGVRSYPVIPVPSKGFGLLQK 343
Query: 183 VPVPSSEH 190
+P P H
Sbjct: 344 LPPPLFPH 351
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 57.0 bits (136), Expect = 5e-08
Identities = 39/110 (35%), Positives = 42/110 (38%), Gaps = 19/110 (17%)
Query: 3 SSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLA 62
S+ P G GGG GG G+GAA P PPP A A P P PPP P +AAA
Sbjct: 42 SAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAA---- 97
Query: 63 LDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAP 112
G AAG G AP P G A AP
Sbjct: 98 ---------------PASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAP 132
Score = 53.5 bits (127), Expect = 6e-07
Identities = 46/146 (31%), Positives = 55/146 (37%), Gaps = 33/146 (22%)
Query: 29 GPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAGDGAA 88
G P PPP+ Q+ PPP + + L + G AG GA G+G
Sbjct: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGG-GAGGEGLG 61
Query: 89 AAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPR-------- 140
AA A P PP P APP PPPPPPP
Sbjct: 62 AAAAA---LLLHPPPPPPPATAAPPP-----------------PPPPPPPPASAAAPASG 101
Query: 141 -PSPPDVFAGFAPHPAALGP-PTLLA 164
P+PP + AG P PA P P L+A
Sbjct: 102 PPAPPGLAAG--PGPAGGAPTPALVA 125
Score = 32.7 bits (73), Expect = 1.1
Identities = 37/134 (27%), Positives = 46/134 (34%), Gaps = 17/134 (12%)
Query: 380 GRRPPTATAGLRGDTALGAPSAPEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGP 439
G+ PP + L P P A A G P ++ S +G+ G G EG
Sbjct: 3 GQPPPPPPQQQQQQQQLSPP--PPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGL 60
Query: 440 GAPVGTAAPDDCDFGFDFDFLALDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAPGPP- 498
GA L P AT P P P S + +G P PP
Sbjct: 61 GAAAAA-------------LLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPG 107
Query: 499 -AAGARRSSGAGTP 511
AAG + GA TP
Sbjct: 108 LAAGPGPAGGAPTP 121
Score = 31.6 bits (70), Expect = 2.4
Identities = 31/100 (31%), Positives = 40/100 (40%), Gaps = 3/100 (3%)
Query: 495 PGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGPVSFPG 554
P PPA A SS AG+P G L L P P A PP P P
Sbjct: 36 PAPPAVSAG-SSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAP--PPPPPPPPPP 92
Query: 555 GAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAP 594
+A + A+ P+ P AA GA + S+++AP
Sbjct: 93 ASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAP 132
Score = 31.6 bits (70), Expect = 2.4
Identities = 31/103 (30%), Positives = 39/103 (37%), Gaps = 7/103 (6%)
Query: 483 PAFSGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRLELPLSRRGAPDPVGALS 542
PA S S+ G+PG A G + A P P P P P P A +
Sbjct: 39 PAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPP---PPPPPPPPASA 95
Query: 543 WRPPQGPVSFPGGAAFSTATSLPSSPA----AAACAPLDSGAS 581
P GP + PG AA +PA ++A AP G S
Sbjct: 96 AAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFPHGDS 138
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 56.6 bits (135), Expect = 7e-08
Identities = 52/153 (33%), Positives = 59/153 (38%), Gaps = 39/153 (25%)
Query: 32 PAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAGDGAAAAG 91
P PP AP PPP P QL G GG G G GAA++
Sbjct: 197 PMEPPTSRMFQAPPGAPPPHP------------QLYPGGTGGVLSGPPMGPKGGGAASSV 244
Query: 92 GADGGAAPEPVPPDGP-------EAGAPPTLAPA--VAPGSLPLLDPNA-------SPPP 135
G G P PP P +GAPPT P V G+LP P A + PP
Sbjct: 245 GGPNGGKQHP-PPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPP 303
Query: 136 PPPPRP------SPPDVFA----GFAPHPAALG 158
PP RP SPP + A G P P A+G
Sbjct: 304 PPALRPLNNASASPPGLGAQPLPGHLPSPHAMG 336
Score = 41.2 bits (95), Expect = 0.003
Identities = 64/310 (20%), Positives = 99/310 (31%), Gaps = 37/310 (11%)
Query: 24 AGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAA 83
AG P PPP G + +P P + + G G G
Sbjct: 626 AGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTF 685
Query: 84 GDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNA----------SP 133
G+ G P P+PP GP +G P P AP S P L +P
Sbjct: 686 KPGSPTVG-------PGPLPPAGP-SGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETP 737
Query: 134 PPPPPPRPSPPDVFAGFAPHPAALGPPTLLADQMSVIGSRKKSVNMTECVPVPSSEHVAE 193
P PP SP +P P + P+ + + N S +
Sbjct: 738 ESPVPPARSP-------SPPPKVVDVPSHASQSARFNKHLDRGFNSC----ARSDLYFVP 786
Query: 194 IVGRQGCKIKA-LRAKTNTYIKTPVRGEEPVFIVTGRKEDVEMAKREILSAAEHFSIIRA 252
+ G + K +A L K + R E+ R+++ E K L + +
Sbjct: 787 LEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGR 846
Query: 253 TRSKAGGLPGAAQGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIVTPGR 312
+ L PP PG V PY +GP ++ + + ++++PG
Sbjct: 847 APVECPSLGPVPHRPPFEPGSAVATVP-PY------LGPDTPALRTLSEYARPHVMSPGN 899
Query: 313 DKEPVFAVTG 322
P + G
Sbjct: 900 RNHPFYVPLG 909
Score = 39.7 bits (91), Expect = 0.009
Identities = 53/211 (25%), Positives = 74/211 (35%), Gaps = 43/211 (20%)
Query: 402 PEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLA 461
P + + S+ GP+ P +S S S + G P +P G + F
Sbjct: 552 PHSQVSYSQAGPNGPPVSSSSNSSSSTSQG--------SYPCSHPSPSQGPQGAPYPFPP 603
Query: 462 LDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPG 521
+ ++AT+ A PA G T + PGPP G R P PG
Sbjct: 604 VPTVTTSSATLSTVIATVASSPA--GYKTAS-PPGPPPYGKRA-------------PSPG 647
Query: 522 GLRLELPLS-RRGAP------DPVGALSWRPPQGPVSFPGG-----------AAFSTATS 563
+ P + G+P P G PP GP +F G A S S
Sbjct: 648 AYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPS 707
Query: 564 LPSSPAAAACAPLDSGASENSRKPPSASSAP 594
LP PAA A P A++ ++P P
Sbjct: 708 LPPPPAAPASGP-PLSATQIKQEPAEEYETP 737
Score = 38.5 bits (88), Expect = 0.020
Identities = 42/166 (25%), Positives = 54/166 (32%), Gaps = 21/166 (12%)
Query: 2 PSSLG-QPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALR 60
P LG QP G G G G PGP P AP+P P +A A
Sbjct: 317 PPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPT------LAPSPHSLPPASSSAPAPP 370
Query: 61 LALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVA 120
+ S+ A + ++ + + P PP P + + P
Sbjct: 371 MRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPP--PTSLSVSNQPPKYT 428
Query: 121 PGSLPLLDP-NASPPPPPP-----------PRPSPPDVFAGFAPHP 154
SLP + PPPPPP P P PP A HP
Sbjct: 429 QPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHP 474
Score = 35.0 bits (79), Expect = 0.22
Identities = 33/137 (24%), Positives = 45/137 (32%), Gaps = 28/137 (20%)
Query: 33 APPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAGDGAAAAGG 92
AP ++ P P+ P + LD L L G +D D + +
Sbjct: 86 APKKTKTEQELPRPQSPSD-----------LDSLDGRSLNDDGSSDPRDIDQDNRSTS-- 132
Query: 93 ADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSPPDVFAGFAP 152
P P E + + + P P P PP P PP +P A F P
Sbjct: 133 ------PSIYSPGSVENDSDSSSGLSQGPAR-PYHPPPLFPPSPQPPDSTPRQPEASFEP 185
Query: 153 HP--------AALGPPT 161
HP A + PPT
Sbjct: 186 HPSVTPTGYHAPMEPPT 202
Score = 35.0 bits (79), Expect = 0.22
Identities = 54/172 (31%), Positives = 57/172 (33%), Gaps = 63/172 (36%)
Query: 5 LGQPDGGGGGGGGGGGV---------------------GAAGEDPGPGP----------- 32
L P G GGG V GA+G P P
Sbjct: 228 LSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPS 287
Query: 33 APPPEGAQEAAPAPRPPPEPDDAAAALR-LALDQLSALGLGG---AGDTDEEGAAGDGAA 88
APPP P PPP ALR L S GLG G A G G
Sbjct: 288 APPPANFPHVTPNLPPPP-------ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQG-- 338
Query: 89 AAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPR 140
GG P GPE G PTLAP +P SLP P +S P PP R
Sbjct: 339 -MGGL----------PPGPEKG--PTLAP--SPHSLP---PASSSAPAPPMR 372
Score = 29.6 bits (65), Expect = 9.1
Identities = 13/41 (31%), Positives = 19/41 (46%)
Query: 104 PDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSPP 144
P+GP + + + + GS P P+ S P P P PP
Sbjct: 563 PNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPP 603
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 56.6 bits (135), Expect = 7e-08
Identities = 52/153 (33%), Positives = 59/153 (38%), Gaps = 39/153 (25%)
Query: 32 PAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAGDGAAAAG 91
P PP AP PPP P QL G GG G G GAA++
Sbjct: 197 PMEPPTSRMFQAPPGAPPPHP------------QLYPGGTGGVLSGPPMGPKGGGAASSV 244
Query: 92 GADGGAAPEPVPPDGP-------EAGAPPTLAPA--VAPGSLPLLDPNA-------SPPP 135
G G P PP P +GAPPT P V G+LP P A + PP
Sbjct: 245 GGPNGGKQHP-PPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPP 303
Query: 136 PPPPRP------SPPDVFA----GFAPHPAALG 158
PP RP SPP + A G P P A+G
Sbjct: 304 PPALRPLNNASASPPGLGAQPLPGHLPSPHAMG 336
Score = 41.2 bits (95), Expect = 0.003
Identities = 64/310 (20%), Positives = 99/310 (31%), Gaps = 37/310 (11%)
Query: 24 AGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAA 83
AG P PPP G + +P P + + G G G
Sbjct: 626 AGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTF 685
Query: 84 GDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNA----------SP 133
G+ G P P+PP GP +G P P AP S P L +P
Sbjct: 686 KPGSPTVG-------PGPLPPAGP-SGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETP 737
Query: 134 PPPPPPRPSPPDVFAGFAPHPAALGPPTLLADQMSVIGSRKKSVNMTECVPVPSSEHVAE 193
P PP SP +P P + P+ + + N S +
Sbjct: 738 ESPVPPARSP-------SPPPKVVDVPSHASQSARFNKHLDRGFNSC----ARSDLYFVP 786
Query: 194 IVGRQGCKIKA-LRAKTNTYIKTPVRGEEPVFIVTGRKEDVEMAKREILSAAEHFSIIRA 252
+ G + K +A L K + R E+ R+++ E K L + +
Sbjct: 787 LEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGR 846
Query: 253 TRSKAGGLPGAAQGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIVTPGR 312
+ L PP PG V PY +GP ++ + + ++++PG
Sbjct: 847 APVECPSLGPVPHRPPFEPGSAVATVP-PY------LGPDTPALRTLSEYARPHVMSPGN 899
Query: 313 DKEPVFAVTG 322
P + G
Sbjct: 900 RNHPFYVPLG 909
Score = 39.7 bits (91), Expect = 0.009
Identities = 53/211 (25%), Positives = 74/211 (35%), Gaps = 43/211 (20%)
Query: 402 PEAFYAGSRGGPSVPDPGPASPYSGSGNGGFAFGAEGPGAPVGTAAPDDCDFGFDFDFLA 461
P + + S+ GP+ P +S S S + G P +P G + F
Sbjct: 552 PHSQVSYSQAGPNGPPVSSSSNSSSSTSQG--------SYPCSHPSPSQGPQGAPYPFPP 603
Query: 462 LDLTVPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPG 521
+ ++AT+ A PA G T + PGPP G R P PG
Sbjct: 604 VPTVTTSSATLSTVIATVASSPA--GYKTAS-PPGPPPYGKRA-------------PSPG 647
Query: 522 GLRLELPLS-RRGAP------DPVGALSWRPPQGPVSFPGG-----------AAFSTATS 563
+ P + G+P P G PP GP +F G A S S
Sbjct: 648 AYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPS 707
Query: 564 LPSSPAAAACAPLDSGASENSRKPPSASSAP 594
LP PAA A P A++ ++P P
Sbjct: 708 LPPPPAAPASGP-PLSATQIKQEPAEEYETP 737
Score = 38.5 bits (88), Expect = 0.020
Identities = 42/166 (25%), Positives = 54/166 (32%), Gaps = 21/166 (12%)
Query: 2 PSSLG-QPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALR 60
P LG QP G G G G PGP P AP+P P +A A
Sbjct: 317 PPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPT------LAPSPHSLPPASSSAPAPP 370
Query: 61 LALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVA 120
+ S+ A + ++ + + P PP P + + P
Sbjct: 371 MRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPP--PTSLSVSNQPPKYT 428
Query: 121 PGSLPLLDP-NASPPPPPP-----------PRPSPPDVFAGFAPHP 154
SLP + PPPPPP P P PP A HP
Sbjct: 429 QPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHP 474
Score = 35.0 bits (79), Expect = 0.22
Identities = 33/137 (24%), Positives = 45/137 (32%), Gaps = 28/137 (20%)
Query: 33 APPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEGAAGDGAAAAGG 92
AP ++ P P+ P + LD L L G +D D + +
Sbjct: 86 APKKTKTEQELPRPQSPSD-----------LDSLDGRSLNDDGSSDPRDIDQDNRSTS-- 132
Query: 93 ADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSPPDVFAGFAP 152
P P E + + + P P P PP P PP +P A F P
Sbjct: 133 ------PSIYSPGSVENDSDSSSGLSQGPAR-PYHPPPLFPPSPQPPDSTPRQPEASFEP 185
Query: 153 HP--------AALGPPT 161
HP A + PPT
Sbjct: 186 HPSVTPTGYHAPMEPPT 202
Score = 35.0 bits (79), Expect = 0.22
Identities = 54/172 (31%), Positives = 57/172 (33%), Gaps = 63/172 (36%)
Query: 5 LGQPDGGGGGGGGGGGV---------------------GAAGEDPGPGP----------- 32
L P G GGG V GA+G P P
Sbjct: 228 LSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPS 287
Query: 33 APPPEGAQEAAPAPRPPPEPDDAAAALR-LALDQLSALGLGG---AGDTDEEGAAGDGAA 88
APPP P PPP ALR L S GLG G A G G
Sbjct: 288 APPPANFPHVTPNLPPPP-------ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQG-- 338
Query: 89 AAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPR 140
GG P GPE G PTLAP +P SLP P +S P PP R
Sbjct: 339 -MGGL----------PPGPEKG--PTLAP--SPHSLP---PASSSAPAPPMR 372
Score = 29.6 bits (65), Expect = 9.1
Identities = 13/41 (31%), Positives = 19/41 (46%)
Query: 104 PDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRPSPP 144
P+GP + + + + GS P P+ S P P P PP
Sbjct: 563 PNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPP 603
>gi|154759423 Cdk5 and Abl enzyme substrate 1 isoform 2 [Homo
sapiens]
Length = 633
Score = 56.2 bits (134), Expect = 9e-08
Identities = 52/152 (34%), Positives = 62/152 (40%), Gaps = 14/152 (9%)
Query: 14 GGGGGGGVGAAG-EDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALDQLSALGLG 72
G G GA+G + P P P P P A A P P PP +P + AL L+ + L
Sbjct: 16 GSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISLD 75
Query: 73 GA--------GDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGP--EAGAPPTLAPAVAPG 122
G G +E GAA GA A GA + G AP T A +A G
Sbjct: 76 GRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAPGTPAAGLAAG 135
Query: 123 SLPLLDPNASPPPPPP---PRPSPPDVFAGFA 151
S P L +S PP P S P V GFA
Sbjct: 136 SGPCLPQPSSLPPLIPGGHATVSGPGVARGFA 167
Score = 33.9 bits (76), Expect = 0.48
Identities = 34/112 (30%), Positives = 45/112 (40%), Gaps = 13/112 (11%)
Query: 487 GCSTVNGAPGPPAAGARRSSGAGTPRHS--PTLPEPGGLRLELPLSRRGAPDPVGA---- 540
GC + APG PAAG SG P+ S P L G + P RG P+GA
Sbjct: 118 GCIAL-AAPGTPAAGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRAS 176
Query: 541 -LSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSAS 591
W+PP+ P A L AA L+ + S + P+A+
Sbjct: 177 GEQWQPPR-----PAPLAACAQLQLLDGSGAAGQEELEEDDAFISVQVPAAA 223
Score = 32.7 bits (73), Expect = 1.1
Identities = 21/73 (28%), Positives = 25/73 (34%), Gaps = 18/73 (24%)
Query: 69 LGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLD 128
+ A T ++G A GA G P P P P A AP
Sbjct: 1 MAAAAAAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAP---------------- 44
Query: 129 PNASPPPPPPPRP 141
A PPP PP +P
Sbjct: 45 --AQPPPEPPRKP 55
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.135 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,595,739
Number of Sequences: 37866
Number of extensions: 2949693
Number of successful extensions: 65938
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1033
Number of HSP's successfully gapped in prelim test: 1911
Number of HSP's that attempted gapping in prelim test: 21191
Number of HSP's gapped (non-prelim): 25750
length of query: 651
length of database: 18,247,518
effective HSP length: 109
effective length of query: 542
effective length of database: 14,120,124
effective search space: 7653107208
effective search space used: 7653107208
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.