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Search of human proteins with 163310747
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|163310747 LIM and calponin homology domains 1 isoform d
[Homo sapiens]
(902 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|163310747 LIM and calponin homology domains 1 isoform d [Homo... 1816 0.0
gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 1803 0.0
gi|163310743 LIM and calponin homology domains 1 isoform b [Homo... 1798 0.0
gi|163310741 LIM and calponin homology domains 1 isoform a [Homo... 1784 0.0
gi|163310749 LIM and calponin homology domains 1 isoform e [Homo... 1781 0.0
gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] 290 3e-78
gi|221316634 LIM domain only 7 isoform 2 [Homo sapiens] 168 2e-41
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 3e-08
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 59 3e-08
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 56 1e-07
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 55 2e-07
gi|238908501 sciellin isoform 3 [Homo sapiens] 55 4e-07
gi|238908499 sciellin isoform 1 [Homo sapiens] 55 4e-07
gi|238908497 sciellin isoform 2 [Homo sapiens] 55 4e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 54 9e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 54 9e-07
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 53 1e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 52 3e-06
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 49 2e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 49 2e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 49 2e-05
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 49 2e-05
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 49 2e-05
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 49 2e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 49 2e-05
gi|148746195 trichohyalin [Homo sapiens] 49 3e-05
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 49 3e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 48 4e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 48 5e-05
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 48 5e-05
>gi|163310747 LIM and calponin homology domains 1 isoform d [Homo
sapiens]
Length = 902
Score = 1816 bits (4703), Expect = 0.0
Identities = 902/902 (100%), Positives = 902/902 (100%)
Query: 1 MDSERQVKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQ 60
MDSERQVKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQ
Sbjct: 1 MDSERQVKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQ 60
Query: 61 TPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKS 120
TPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKS
Sbjct: 61 TPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKS 120
Query: 121 NQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCE 180
NQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCE
Sbjct: 121 NQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCE 180
Query: 181 EEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEK 240
EEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEK
Sbjct: 181 EEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEK 240
Query: 241 LLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISE 300
LLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISE
Sbjct: 241 LLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISE 300
Query: 301 AVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLD 360
AVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLD
Sbjct: 301 AVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLD 360
Query: 361 TSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKE 420
TSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKE
Sbjct: 361 TSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKE 420
Query: 421 RECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTE 480
RECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTE
Sbjct: 421 RECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTE 480
Query: 481 PNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQ 540
PNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQ
Sbjct: 481 PNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQ 540
Query: 541 KKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSE 600
KKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSE
Sbjct: 541 KKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSE 600
Query: 601 KSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEER 660
KSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEER
Sbjct: 601 KSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEER 660
Query: 661 RYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKS 720
RYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKS
Sbjct: 661 RYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKS 720
Query: 721 FQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQ 780
FQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQ
Sbjct: 721 FQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQ 780
Query: 781 LAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLG 840
LAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLG
Sbjct: 781 LAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLG 840
Query: 841 KGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPT 900
KGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPT
Sbjct: 841 KGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPT 900
Query: 901 TL 902
TL
Sbjct: 901 TL 902
>gi|163310745 LIM and calponin homology domains 1 isoform c [Homo
sapiens]
Length = 1056
Score = 1803 bits (4669), Expect = 0.0
Identities = 895/895 (100%), Positives = 895/895 (100%)
Query: 8 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 67
KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV
Sbjct: 162 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 221
Query: 68 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 127
LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP
Sbjct: 222 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 281
Query: 128 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 187
APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP
Sbjct: 282 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 341
Query: 188 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 247
HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG
Sbjct: 342 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 401
Query: 248 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 307
TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE
Sbjct: 402 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 461
Query: 308 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 367
MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS
Sbjct: 462 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 521
Query: 368 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 427
GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA
Sbjct: 522 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 581
Query: 428 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 487
PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK
Sbjct: 582 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 641
Query: 488 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 547
NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM
Sbjct: 642 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 701
Query: 548 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 607
SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP
Sbjct: 702 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 761
Query: 608 FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER 667
FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER
Sbjct: 762 FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER 821
Query: 668 KIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSD 727
KIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSD
Sbjct: 822 KIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSD 881
Query: 728 LLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQ 787
LLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQ
Sbjct: 882 LLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQ 941
Query: 788 NQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMII 847
NQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMII
Sbjct: 942 NQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMII 1001
Query: 848 ETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 902
ETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL
Sbjct: 1002 ETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1056
>gi|163310743 LIM and calponin homology domains 1 isoform b [Homo
sapiens]
Length = 1057
Score = 1798 bits (4657), Expect = 0.0
Identities = 895/896 (99%), Positives = 895/896 (99%), Gaps = 1/896 (0%)
Query: 8 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 67
KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV
Sbjct: 162 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 221
Query: 68 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 127
LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP
Sbjct: 222 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 281
Query: 128 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 187
APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP
Sbjct: 282 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 341
Query: 188 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 247
HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG
Sbjct: 342 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 401
Query: 248 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 307
TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE
Sbjct: 402 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 461
Query: 308 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 367
MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS
Sbjct: 462 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 521
Query: 368 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 427
GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA
Sbjct: 522 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 581
Query: 428 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 487
PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK
Sbjct: 582 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 641
Query: 488 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 547
NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM
Sbjct: 642 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 701
Query: 548 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 607
SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP
Sbjct: 702 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 761
Query: 608 -FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE 666
FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE
Sbjct: 762 QFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE 821
Query: 667 RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS 726
RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS
Sbjct: 822 RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS 881
Query: 727 DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS 786
DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS
Sbjct: 882 DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS 941
Query: 787 QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMI 846
QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMI
Sbjct: 942 QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMI 1001
Query: 847 IETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 902
IETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL
Sbjct: 1002 IETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1057
>gi|163310741 LIM and calponin homology domains 1 isoform a [Homo
sapiens]
Length = 1083
Score = 1784 bits (4620), Expect = 0.0
Identities = 895/922 (97%), Positives = 895/922 (97%), Gaps = 27/922 (2%)
Query: 8 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 67
KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV
Sbjct: 162 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 221
Query: 68 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 127
LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP
Sbjct: 222 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 281
Query: 128 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 187
APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP
Sbjct: 282 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 341
Query: 188 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 247
HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG
Sbjct: 342 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 401
Query: 248 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 307
TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE
Sbjct: 402 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 461
Query: 308 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 367
MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS
Sbjct: 462 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 521
Query: 368 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 427
GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA
Sbjct: 522 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 581
Query: 428 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 487
PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK
Sbjct: 582 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 641
Query: 488 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 547
NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM
Sbjct: 642 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 701
Query: 548 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 607
SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP
Sbjct: 702 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 761
Query: 608 -FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE 666
FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE
Sbjct: 762 QFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE 821
Query: 667 RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS 726
RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS
Sbjct: 822 RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS 881
Query: 727 DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS 786
DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS
Sbjct: 882 DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS 941
Query: 787 QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRK---------------------- 824
QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRK
Sbjct: 942 QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKKSPREHFQAGPFSPCSPTPPGQ 1001
Query: 825 ----SISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIR 880
SISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIR
Sbjct: 1002 SPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIR 1061
Query: 881 NGLLNCNDCYMRSRSAGQPTTL 902
NGLLNCNDCYMRSRSAGQPTTL
Sbjct: 1062 NGLLNCNDCYMRSRSAGQPTTL 1083
>gi|163310749 LIM and calponin homology domains 1 isoform e [Homo
sapiens]
Length = 890
Score = 1781 bits (4614), Expect = 0.0
Identities = 890/902 (98%), Positives = 890/902 (98%), Gaps = 12/902 (1%)
Query: 1 MDSERQVKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQ 60
MDSERQVKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQ
Sbjct: 1 MDSERQVKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQ 60
Query: 61 TPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKS 120
TPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKS
Sbjct: 61 TPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKS 120
Query: 121 NQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCE 180
NQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFR STSMFDMRCE
Sbjct: 121 NQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFR------------STSMFDMRCE 168
Query: 181 EEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEK 240
EEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEK
Sbjct: 169 EEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEK 228
Query: 241 LLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISE 300
LLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISE
Sbjct: 229 LLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISE 288
Query: 301 AVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLD 360
AVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLD
Sbjct: 289 AVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLD 348
Query: 361 TSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKE 420
TSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKE
Sbjct: 349 TSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKE 408
Query: 421 RECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTE 480
RECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTE
Sbjct: 409 RECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTE 468
Query: 481 PNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQ 540
PNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQ
Sbjct: 469 PNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQ 528
Query: 541 KKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSE 600
KKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSE
Sbjct: 529 KKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSE 588
Query: 601 KSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEER 660
KSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEER
Sbjct: 589 KSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEER 648
Query: 661 RYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKS 720
RYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKS
Sbjct: 649 RYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKS 708
Query: 721 FQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQ 780
FQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQ
Sbjct: 709 FQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQ 768
Query: 781 LAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLG 840
LAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLG
Sbjct: 769 LAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLG 828
Query: 841 KGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPT 900
KGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPT
Sbjct: 829 KGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPT 888
Query: 901 TL 902
TL
Sbjct: 889 TL 890
>gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens]
Length = 1349
Score = 290 bits (743), Expect = 3e-78
Identities = 249/852 (29%), Positives = 404/852 (47%), Gaps = 143/852 (16%)
Query: 8 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHG-RDDSFDSLDSFGSRSRQTPSPDV 66
K +D KRS RDSGY D W ER + L+PPRH R+DSF+SLDS GSRS + S D+
Sbjct: 206 KALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRHHKREDSFESLDSLGSRSLTSCSSDI 265
Query: 67 VLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYV 126
LRG +G SD++S+ K+ D KDDMS RR S EPK+A+PFN++LPNKS Q +YV
Sbjct: 266 TLRGGREGFESDTDSEFTF-KMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYV 324
Query: 127 PAPLRKKKAER-EEYRKSWSTATSPLGGERPFRYGPR-TPVSDDAESTSMFDMRCEEEAA 184
PAPLRKKK ++ E+ R+SW+ SP+ E + + + S SM D+ E+
Sbjct: 325 PAPLRKKKPDKHEDNRRSWA---SPVYTEADGTFSRLFQKIYGENGSKSMSDVSAED--- 378
Query: 185 VQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAG 244
VQ + R E++Q I +QL+E+D KWQDDLA+WK RR+S + DL KK+EER+++EK
Sbjct: 379 VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEK---- 434
Query: 245 EDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ--YIERFTISEAV 302
+ ++S KT++E++Q++E + ++ + R + +L++ T+SEA
Sbjct: 435 -QALEKSKRSSKTFKEMLQDRESQNQK--STVPSRRRMYSFDDVLEEGKRPPTMTVSEAS 491
Query: 303 L--ERLEMPKILERSHSTEPNLSSFLNDPNPMK---YLRQQSLPPPKFTATVETTIARAS 357
ER+E S + + ++F + + L QS + A++ + +R++
Sbjct: 492 YQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRST 551
Query: 358 VLDTSMSAGS--GSPSKTVTPKAVPMLTPKPY-SQPKNSQDVLKTFKVDGKVSVNG---- 410
++++ + S S KT T + ++TP+P+ SQ + + +++ +D NG
Sbjct: 552 QMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVED 611
Query: 411 -----------------------------ETVHREEEKERECPTVAPAHSLTKSQMFEGV 441
E EE+ R +P SL++ Q
Sbjct: 612 IKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSK 671
Query: 442 ARVHG-SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIEL 500
A + S L+L ++G EI S +E++ + ++ GKS +
Sbjct: 672 ATLSSTSGLDLMSESGEGEI------SPQREVSRSQDQFSDMRISINQTPGKSLDFGFTI 725
Query: 501 ASSEPQHFTTTVTRCSPTVAFVEFPSSPQ---LKNDVSEEKDQKKPENEMSGKVE---LV 554
P F +V SP F + + + N D K+ E M+ E LV
Sbjct: 726 KWDIPGIFVASVEAGSP-AEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLV 784
Query: 555 LS-QKVVKPKSPEPE----------------ATLTFPFLDKMPEAN-------------- 583
+ ++ K SPE + ++T F + + +N
Sbjct: 785 MDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESN 844
Query: 584 --------QLHLPNL--NSQVDSPSSEKS-------PVMTPFKFWAWDPEEERRRQEKWQ 626
+ L NL SQ S S P ++ W WD EEER+RQE+WQ
Sbjct: 845 AFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQ 904
Query: 627 QEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTV------- 679
+EQ+RLLQE+YQ+EQ+KL+EEW++A++E E E +Y +EE ++ + T
Sbjct: 905 KEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLAT 964
Query: 680 -------SSSSADQLSTSSSMTEGSGTMNKI---DLG-NCQDE---KQDRRWKKSFQGDD 725
S S+D+ T + E ++ D G QD+ +++R+W++ Q +
Sbjct: 965 WEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQ 1024
Query: 726 SDLLLKTRESDR 737
L+ ++
Sbjct: 1025 EQKRLQAEAEEQ 1036
Score = 113 bits (282), Expect = 9e-25
Identities = 101/343 (29%), Positives = 160/343 (46%), Gaps = 60/343 (17%)
Query: 616 EEERRRQEKWQQEQERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDT 673
E ER+ +++ Q+EQE Q+R Q E ++ K E +K Q E+E E + R+ ++
Sbjct: 1011 ERERKWEQQLQEEQE---QKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSY 1067
Query: 674 VVPFTVSSSS----ADQLSTSSS------MTEGSGTMNKID-LGNC-------------- 708
+P T +SS D+ + S+ T +G +D +GN
Sbjct: 1068 DIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPS 1127
Query: 709 ------QDEKQDRRWKKSFQGDDSDLLLKTRESDR--LEEKGSLTEG-ALAHSGNPVSKG 759
Q Q+ R + D+S + ++ ++ + G + G +L + +P S
Sbjct: 1128 GAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNS 1187
Query: 760 VHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN-----------PTHSSEDVKPKT--L 806
+ L+ G + ++ P Q TSN P S+ VK T +
Sbjct: 1188 WRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGV 1247
Query: 807 PLDKSINHQIESPSE-------RRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCF 859
+S + SPS R +S+SGK++CS C LGKGAAMIIE+L L +H+ CF
Sbjct: 1248 ATTQSPTPRSHSPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCF 1307
Query: 860 RCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 902
+C C+ LG + SG +VRIRN L CNDCY+R +S G+PT +
Sbjct: 1308 KCVACECDLGGSSSGAEVRIRNHQLYCNDCYLRFKS-GRPTAM 1349
Score = 31.6 bits (70), Expect = 3.5
Identities = 58/271 (21%), Positives = 102/271 (37%), Gaps = 39/271 (14%)
Query: 170 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 229
E ++ + +EE + +EQ + Q R+ + + + + ++ RR S D+
Sbjct: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1070
Query: 230 KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 281
K EE +R K +D ++ + + K +I + R E + +
Sbjct: 1071 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1129
Query: 282 QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 324
+ E + ILQ+ +R + + E + +P I+ R S + NL S
Sbjct: 1130 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1188
Query: 325 ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 377
+LN P ++ S PPP+ +T R +S+ S KT T
Sbjct: 1189 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1246
Query: 378 AVPMLTPKPYS-QPKNSQ--DVLKTFKVDGK 405
+P P S P SQ L+ V GK
Sbjct: 1247 VATTQSPTPRSHSPSASQSGSQLRNRSVSGK 1277
>gi|221316634 LIM domain only 7 isoform 2 [Homo sapiens]
Length = 1385
Score = 168 bits (425), Expect = 2e-41
Identities = 188/765 (24%), Positives = 329/765 (43%), Gaps = 149/765 (19%)
Query: 92 KKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPL 151
KKDDM R+ + + VP + P ++ A L++ +A RE R L
Sbjct: 351 KKDDMLTRKIQSWKLGTTVPPISFTPGPCSE-----ADLKRWEAIREASRLRHKKR---L 402
Query: 152 GGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQ 211
ER F+ + + S SM D+ E+ VQ + R E++Q I +QL+E+D KWQ
Sbjct: 403 MVERLFQ-----KIYGENGSKSMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQ 454
Query: 212 DDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERE 271
DDLA+WK RR+S + DL KK+EER+++EK + ++S KT++E++Q++E + ++
Sbjct: 455 DDLAKWKDRRKSYTSDLQKKKEEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK 509
Query: 272 LHEAYKNARSQEEAEGILQQ--YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLN 327
+ R + +L++ T+SEA ER+E S + + ++F
Sbjct: 510 --STVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAK 567
Query: 328 DPNPMK---YLRQQSLPPPKFTATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPML 382
+ + L QS + A++ + +R++ ++++ + S S KT T + ++
Sbjct: 568 REDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVV 627
Query: 383 TPKPY-SQPKNSQDVLKTFKVDGKVSVNG------------------------------- 410
TP+P+ SQ + + +++ +D NG
Sbjct: 628 TPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSS 687
Query: 411 --ETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNS 467
E EE+ R +P SL++ Q A + S L+L ++G EI S
Sbjct: 688 QKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEI------S 741
Query: 468 VPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSS 527
+E++ + ++ GKS + P F +V SP F +
Sbjct: 742 PQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVD 800
Query: 528 PQ---LKNDVSEEKDQKKPENEMSGKVE---LVLS-QKVVKPKSPEPE------------ 568
+ + N D K+ E M+ E LV+ ++ K SPE +
Sbjct: 801 DEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSE 860
Query: 569 ----ATLTFPFLDKMPEAN----------------------QLHLPNL--NSQVDSPSSE 600
++T F + + +N + L NL SQ S
Sbjct: 861 KSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSS 920
Query: 601 KS-------PVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQK 653
S P ++ W WD EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A++
Sbjct: 921 DSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQ 980
Query: 654 EVEEEERRYYEEERKIIEDTVVPFTV--------------SSSSADQLSTSSSMTEGSGT 699
E E E +Y +EE ++ + T S S+D+ T + E
Sbjct: 981 EAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQP 1040
Query: 700 MNKI---DLG-NCQDE---KQDRRWKKSFQGDDSDLLLKTRESDR 737
++ D G QD+ +++R+W++ Q + L+ ++
Sbjct: 1041 QEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQ 1085
Score = 77.0 bits (188), Expect = 7e-14
Identities = 36/60 (60%), Positives = 48/60 (80%), Gaps = 1/60 (1%)
Query: 88 LPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAER-EEYRKSWST 146
+ D KDDMS RR S EPK+A+PFN++LPNKS Q +YVPAPLRKKK ++ E+ R+SW++
Sbjct: 1 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 60
Score = 38.1 bits (87), Expect = 0.037
Identities = 18/54 (33%), Positives = 37/54 (68%)
Query: 615 PEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERK 668
P+EE +++ ++ Q++L+ ER +K + +L+EE E+ + + E EE++ EE+K
Sbjct: 1040 PQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQK 1093
Score = 36.2 bits (82), Expect = 0.14
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 53 SFGSRSRQTPSPDV----VLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKS 108
+F S R+ +V ++G+S E R +P++ KDD+ R+ S P
Sbjct: 69 TFSSNQRRIWGTNVENWPTVQGTSKSSCYLEEEKAKTRSIPNIVKDDLYVRKLSPVMPNP 128
Query: 109 AVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSW 144
F+Q+LP + P + K+ +RE Y K W
Sbjct: 129 GNAFDQFLPK-----CWTPEDVNWKRIKRETY-KPW 158
Score = 35.0 bits (79), Expect = 0.31
Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 3/66 (4%)
Query: 621 RQEKWQQE-QERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDTVVPF 677
R+ KW+Q+ QE Q+R Q E ++ K E +K Q E+E E + R+ ++ +P
Sbjct: 1061 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPK 1120
Query: 678 TVSSSS 683
T +SS
Sbjct: 1121 TEEASS 1126
Score = 33.1 bits (74), Expect = 1.2
Identities = 61/301 (20%), Positives = 112/301 (37%), Gaps = 37/301 (12%)
Query: 170 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 229
E ++ + +EE + +EQ + Q R+ + + + + ++ RR S D+
Sbjct: 1060 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1119
Query: 230 KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 281
K EE +R K +D ++ + + K +I + R E + +
Sbjct: 1120 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1178
Query: 282 QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 324
+ E + ILQ+ +R + + E + +P I+ R S + NL S
Sbjct: 1179 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1237
Query: 325 ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 377
+LN P ++ S PPP+ +T R +S+ S KT T
Sbjct: 1238 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1295
Query: 378 AVPMLTPKPYS-QPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQ 436
+P P S P SQ + VSV E + +E + E +++ S
Sbjct: 1296 VATTQSPTPRSHSPSASQSGSQLRNSVLPVSVTSEALPQELKSGSETTNCTATTAISDSN 1355
Query: 437 M 437
+
Sbjct: 1356 L 1356
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 58.5 bits (140), Expect = 3e-08
Identities = 99/526 (18%), Positives = 209/526 (39%), Gaps = 57/526 (10%)
Query: 178 RCEEEAAVQPHS-RARQEQLQLINNQLREEDDKWQDD---LARWKSRRRSVSQDLIKKEE 233
R EEE Q R ++E++ +LRE++ K ++ + R + R R ++L ++E+
Sbjct: 276 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEK 335
Query: 234 ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE----RRERELHEAYKNARSQE------ 283
E ++ ++L E+ E+ + + E ++E+E R+E L E K R QE
Sbjct: 336 ELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 395
Query: 284 -----EAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQ 338
E + L++ ER E + E++E + ++ E + +R++
Sbjct: 396 EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRER 455
Query: 339 SLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLK 398
K ET + + K + +P K + Q K + K
Sbjct: 456 E---KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512
Query: 399 TFKVDGKVSVNGETVHRE-----EEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQ 453
++ + K+ E +E +EK RE + QM+E ++ ++
Sbjct: 513 IWEQEEKIRDQEEMWGQEKKMWRQEKMRE----------QEDQMWEQEEKMRDQEQKMWD 562
Query: 454 DNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVT 513
+E ++ QE ++ + +E + K + E+ + +
Sbjct: 563 QEERMEKKTQE-----QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 617
Query: 514 RCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTF 573
+ + K EEK Q++ E + ++ ++ + + PE
Sbjct: 618 KMQ----------EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667
Query: 574 PFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDP---EEERRRQEKWQQEQE 630
+KM E ++ + EK K W + EE R +EK +E+E
Sbjct: 668 WEHEKMQEQEKMQEQE-EKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726
Query: 631 RLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVP 676
+++E+ +K Q++ +E+ ++ ++E+ E+E + +E+E K+ E +P
Sbjct: 727 EMMREQEEKMQEQ-EEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP 771
Score = 45.4 bits (106), Expect = 2e-04
Identities = 35/162 (21%), Positives = 73/162 (45%), Gaps = 8/162 (4%)
Query: 131 RKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSR 190
R +K +E+ +K+W ER + ++ M+ +EE + +
Sbjct: 566 RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEK 625
Query: 191 A--RQEQLQLINNQLREEDDK-WQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 247
++E++Q ++ E+++K W+ + W+ +R ++ + + E+ ++ EK+ E+
Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEK 685
Query: 248 TSERRKSIKTYREIV-----QEKERRERELHEAYKNARSQEE 284
E+ K K +E QEK R E + E K R +EE
Sbjct: 686 IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Score = 43.9 bits (102), Expect = 7e-04
Identities = 30/140 (21%), Positives = 66/140 (47%), Gaps = 17/140 (12%)
Query: 613 WDPEEERRRQEK---------WQQEQERLLQERYQKEQDKLKEEWEK--AQKEVEEEERR 661
W+ E++ R QE+ W+Q++ +E +EQ+K+ E+ EK +K+++E+E++
Sbjct: 379 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKK 438
Query: 662 YYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSF 721
++E K+ E+ + +M E M K + E++++ W++
Sbjct: 439 TRDQEEKMQEEE----RIREREKKMREEEETMREQEEKMQKQE--ENMWEQEEKEWQQQR 492
Query: 722 QGDDSDLLLKTRESDRLEEK 741
+ + L + + EEK
Sbjct: 493 LPEQKEKLWEQEKMQEQEEK 512
Score = 43.9 bits (102), Expect = 7e-04
Identities = 44/225 (19%), Positives = 99/225 (44%), Gaps = 21/225 (9%)
Query: 536 EEKDQK-KPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHL------- 587
E++DQ + E +M + + + Q+ K + + T+ +KM E ++
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 588 -PNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEK--WQQEQERLLQERYQKEQDKL 644
+ + + E+ M + W+ EE+ + QE+ W+QE++ QE EQ +L
Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL 660
Query: 645 KEEWEK--------AQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEG 696
E+ EK Q++++E+E + +E+E+ +E + +++ SM E
Sbjct: 661 PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEK--MEKKTQEQEKKTWDQEKMREEESMRER 718
Query: 697 SGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEK 741
M + + + E++ + ++ Q + ++ + + EEK
Sbjct: 719 EKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK 763
Score = 43.5 bits (101), Expect = 9e-04
Identities = 30/147 (20%), Positives = 72/147 (48%), Gaps = 9/147 (6%)
Query: 177 MRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERK 236
+R +EE Q RQE+++ +Q+ E+++K +D + + + + ++E++
Sbjct: 520 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTW 579
Query: 237 KMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAY---------KNARSQEEAEG 287
E+ + E+ ER K ++ E+++E+E + +E E + + QE+ E
Sbjct: 580 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEK 639
Query: 288 ILQQYIERFTISEAVLERLEMPKILER 314
+ +Q + + E + E+ +P+ E+
Sbjct: 640 MWEQEEKMWEQEEKMWEQQRLPEQKEK 666
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 13/140 (9%)
Query: 545 NEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQV--------DS 596
NE K L +K+ +S + E L L + E + LP + + +
Sbjct: 220 NEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 279
Query: 597 PSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLL--QERYQKEQDKLKEEWEK---A 651
E+ + + W EE R QE +EQE + QE+ +EQ+K E EK
Sbjct: 280 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELRE 339
Query: 652 QKEVEEEERRYYEEERKIIE 671
QKE+ E+E + E+E K+ E
Sbjct: 340 QKELREQEEQMQEQEEKMWE 359
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/137 (24%), Positives = 67/137 (48%), Gaps = 23/137 (16%)
Query: 614 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVE---EEERRYYEEERKII 670
+ EE R QE+ QEQE E+ Q++++K+ E+ EK Q++ E E+E + +E+E K+
Sbjct: 600 EEEEMMREQEEKMQEQE----EKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 655
Query: 671 EDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRW-KKSFQGDDSDLL 729
E +P ++L M E E++++ W ++ + +
Sbjct: 656 EQQRLP-----EQKEKLWEHEKMQEQEK----------MQEQEEKIWEQEKMEKKTQEQE 700
Query: 730 LKTRESDRLEEKGSLTE 746
KT + +++ E+ S+ E
Sbjct: 701 KKTWDQEKMREEESMRE 717
Score = 39.7 bits (91), Expect = 0.013
Identities = 41/148 (27%), Positives = 69/148 (46%), Gaps = 23/148 (15%)
Query: 537 EKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDS 596
E +K P E S K E+ L+ K +K K + FL + N L + +
Sbjct: 229 ELQEKLPLAE-SEKSEIQLNVKELKRKLERAK------FLLPQVQTNTLQEEMWRQEEEL 281
Query: 597 PSSEKSPVMTPFKFWAWDPEEERRRQEK----------WQQEQERLLQERYQKEQDK-LK 645
EK K W +EER R+++ W+QE+ QE+ +EQ+K L+
Sbjct: 282 REQEKKIRKQEEKMWR---QEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR 338
Query: 646 EEWEKAQKE--VEEEERRYYEEERKIIE 671
E+ E ++E ++E+E + +E+E K+ E
Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMRE 366
Score = 39.3 bits (90), Expect = 0.017
Identities = 76/483 (15%), Positives = 187/483 (38%), Gaps = 29/483 (6%)
Query: 190 RARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKK-MEKLLAGEDGT 248
R ++E++ + +LRE++++ ++ W+ + + ++++E++ + E+ + E+
Sbjct: 393 RDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERI 452
Query: 249 SERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEM 308
ER K ++ E ++E+E + ++ E +E + L + E+ E + E+ E
Sbjct: 453 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE- 511
Query: 309 PKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSG 368
KI E+ + + + + + + + + D
Sbjct: 512 -KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD-------- 562
Query: 369 SPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAP 428
+ K K + Q + ++ + + + K+ E + +EEK +E
Sbjct: 563 --QEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQ 620
Query: 429 AHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKN 488
+ E + E ++ E + + +P++ E + QE
Sbjct: 621 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQ 680
Query: 489 DGGKS--RKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENE 546
+ + + +E + E + T + + E + + ++ E+++K E E
Sbjct: 681 EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQE 740
Query: 547 --MSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPV 604
M + E + Q+ K E E + ++PE + + Q E+
Sbjct: 741 EKMQEQEEEMWEQE---EKMWEQEEKMWEQ--QRLPEQKEKLWEHEKMQEQEKIWEQEEK 795
Query: 605 MTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYE 664
M D EE+ R QE+ + QE ++ + +K + ++ W + +K +EE+ + +
Sbjct: 796 MR-------DQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQ 848
Query: 665 EER 667
EE+
Sbjct: 849 EEK 851
Score = 38.9 bits (89), Expect = 0.022
Identities = 32/127 (25%), Positives = 64/127 (50%), Gaps = 5/127 (3%)
Query: 616 EEER-RRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTV 674
EEER R +EK +E+E ++E+ +K Q + + WE+ +KE +++ R E++ K+ E
Sbjct: 448 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ--RLPEQKEKLWEQEK 505
Query: 675 VPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRE 734
+ +Q E G K+ E++D+ W++ + D + + +E
Sbjct: 506 MQ-EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 564
Query: 735 SDRLEEK 741
+R+E+K
Sbjct: 565 -ERMEKK 570
Score = 38.5 bits (88), Expect = 0.028
Identities = 30/175 (17%), Positives = 83/175 (47%), Gaps = 16/175 (9%)
Query: 130 LRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHS 189
LR+K+ E K W E+ + + + + T + + +EE ++
Sbjct: 406 LREKEERMREQEKMW---------EQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRERE 456
Query: 190 RARQEQLQLINNQ----LREEDDKWQDDLARWKSRRRSVSQD-LIKKEEERKKMEKLLAG 244
+ +E+ + + Q ++E++ W+ + W+ +R ++ L ++E+ +++ EK+
Sbjct: 457 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ 516
Query: 245 EDGTSERRKSIKTYREIVQEKERRERE--LHEAYKNARSQEEAEGILQQYIERFT 297
E+ ++ + +++ ++++ RE+E + E + R QE+ ++ +E+ T
Sbjct: 517 EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKT 571
Score = 36.6 bits (83), Expect = 0.11
Identities = 18/60 (30%), Positives = 36/60 (60%), Gaps = 3/60 (5%)
Query: 613 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEK---AQKEVEEEERRYYEEERKI 669
W EE+ QE+ QE ++E+ Q +++K++E+ EK ++++ E+E + +E KI
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 35.8 bits (81), Expect = 0.18
Identities = 20/99 (20%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
Query: 180 EEEAAVQPHSRARQEQLQLINNQLRE----EDDKWQDDLARWKSRRRSVSQDLIKKEEER 235
EEE ++ QEQ + + Q E E+ W+ + W+ +R ++ + + E+
Sbjct: 724 EEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 783
Query: 236 KKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHE 274
++ EK+ E+ ++ + ++ E ++ +E + R E
Sbjct: 784 QEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEE 822
Score = 35.0 bits (79), Expect = 0.31
Identities = 29/133 (21%), Positives = 64/133 (48%), Gaps = 9/133 (6%)
Query: 614 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDT 673
+ EE+ + QE+ EQE ++E+ +K + + WE+ ++ E+E++ +EER +D
Sbjct: 345 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 404
Query: 674 VVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTR 733
+ +++ M E M + + + EK+ R ++ Q ++ ++ R
Sbjct: 405 RL-----REKEERMREQEKMWEQVEKMRE-EKKMQEQEKKTRDQEEKMQEEER---IRER 455
Query: 734 ESDRLEEKGSLTE 746
E EE+ ++ E
Sbjct: 456 EKKMREEEETMRE 468
Score = 33.5 bits (75), Expect = 0.92
Identities = 25/125 (20%), Positives = 64/125 (51%), Gaps = 10/125 (8%)
Query: 177 MRCEEEAAVQPHSRARQEQLQLINNQ-LREEDDKWQDDLARWKSRRRSVSQDLIKKEEE- 234
MR +EE + R R+++ ++ + + E+ +K +++ + +++ Q+ +EEE
Sbjct: 392 MRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEER 451
Query: 235 -RKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRE-------RELHEAYKNARSQEEAE 286
R++ +K+ E+ E+ + ++ E + E+E +E + + ++ + QE+ E
Sbjct: 452 IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 511
Query: 287 GILQQ 291
I +Q
Sbjct: 512 KIWEQ 516
Score = 32.3 bits (72), Expect = 2.0
Identities = 22/99 (22%), Positives = 47/99 (47%), Gaps = 6/99 (6%)
Query: 177 MRCEEEAAVQPHSRARQEQLQLINNQLREEDDK-WQDDLARWKSRRRSVSQDLIKKEEER 235
MR +EE R ++E+++ ++R +++K W + W + Q+ +E
Sbjct: 796 MRDQEEKM-----RGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEE 850
Query: 236 KKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHE 274
K EK+ E+ E+ + ++ E ++E+E + R E
Sbjct: 851 KMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEE 889
Score = 31.2 bits (69), Expect = 4.5
Identities = 26/142 (18%), Positives = 66/142 (46%), Gaps = 2/142 (1%)
Query: 168 DAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLRE-EDDKWQDDLARWKSRRRSVSQ 226
+AE + E++ +Q + + + +L+ L + + + Q+++ R + R +
Sbjct: 227 NAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEK 286
Query: 227 DLIKKEEERKKMEKLLAGEDGTS-ERRKSIKTYREIVQEKERRERELHEAYKNARSQEEA 285
+ K+EE+ + E+ L ++G E+ + + + ++E+E+ RE + + + E
Sbjct: 287 KIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQ 346
Query: 286 EGILQQYIERFTISEAVLERLE 307
E +Q+ E+ E + E
Sbjct: 347 EEQMQEQEEKMWEQEEKMREQE 368
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 58.5 bits (140), Expect = 3e-08
Identities = 137/612 (22%), Positives = 221/612 (36%), Gaps = 81/612 (13%)
Query: 229 IKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGI 288
+K EE+ K +EK E+ + + E+ +E+E+ +E + +EEAEG
Sbjct: 438 VKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGG 497
Query: 289 LQQY----IERFTISE-----AVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQS 339
++ E E V E + P + E + + P K ++
Sbjct: 498 EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 557
Query: 340 LPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKT 399
P + E A++ A SP K +P +P P+ ++ +K
Sbjct: 558 AKSPPEAKSPEKEEAKS-------PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKE 610
Query: 400 FKVDGKVSVNGETVHREEEKE-RECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSI 458
+ K ++ +EE K E + A S TK + SP + K
Sbjct: 611 ---EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEA--------KSPEKAKSP---- 655
Query: 459 EINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPT 518
+K + E A + K E S E K+ + E A S + + +
Sbjct: 656 ----EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSP 711
Query: 519 VAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDK 578
V E S + K+ V EE K PE S E S + K KSPE TL K
Sbjct: 712 VK-EEAKSPEKAKSPVKEE--AKTPEKAKSPVKEEAKSPE--KAKSPEKAKTLDV----K 762
Query: 579 MPEANQLHLPNLNSQVDS-PSSEKSPV----------MTPFKFWAWDPEEE--RRRQEKW 625
PEA S D P KSPV +P K A PE+E ++ + K
Sbjct: 763 SPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKS 822
Query: 626 QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD 685
++E QE KE K EE EKA + EE++ ++E ++ P
Sbjct: 823 PVKEEEKPQEVKVKEPPKKAEE-EKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA 881
Query: 686 QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT 745
S E ++E +D++ K ++ ++ +E + +EK T
Sbjct: 882 VEKPKESKVEAK-----------KEEAEDKK-KVPTPEKEAPAKVEVKEDAKPKEK---T 926
Query: 746 EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQT------SNPTHSSE 799
E A + +K + + EA T + A+ P + +T + T S E
Sbjct: 927 EVAKKEPDDAKAKEPSKPAE-KKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE 985
Query: 800 DVKPKTLPLDKS 811
KPK +KS
Sbjct: 986 PSKPKAEKAEKS 997
Score = 52.0 bits (123), Expect = 2e-06
Identities = 108/551 (19%), Positives = 205/551 (37%), Gaps = 68/551 (12%)
Query: 128 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 187
+P K E+EE KS + SP + P + ++P + E ++ +
Sbjct: 526 SPAEAKSPEKEE-AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKA 584
Query: 188 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 247
S A++E + E+ + A+ + +S ++ K E K EK +
Sbjct: 585 KSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK---AKSP 641
Query: 248 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 307
T E KS ++ + E+E ++ + A+S +AE + + +EA
Sbjct: 642 TKEEAKS-------PEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 308 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 367
+ E + S E S +++++ P K + V+ + + +
Sbjct: 695 KSPVKEEAKSPEKAKSP----------VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744
Query: 368 GSPSKTVTP---KAVPMLTPKPYSQPKN-SQDVLKTFKVDGKVSVNGETVHREEEKER-E 422
SP K +P K + + +P+ + K ++ F K V E E+ K +
Sbjct: 745 KSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLK 804
Query: 423 CPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPN 482
AP + K + + + P E+K + P +E A T KTE
Sbjct: 805 EDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVK--------EPPKKAEEEKAPATPKTEEK 856
Query: 483 SQEDKNDGGKSR--KGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQ 540
K + K K +E EP VE P +++ E +D+
Sbjct: 857 KDSKKEEAPKKEAPKPKVE-EKKEPA---------------VEKPKESKVEAKKEEAEDK 900
Query: 541 KK---PENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSP 597
KK PE E KVE+ ++ KPK A K P+ + P+ ++
Sbjct: 901 KKVPTPEKEAPAKVEV---KEDAKPKEKTEVAK-------KEPDDAKAKEPSKPAEKKEA 950
Query: 598 SSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEE 657
+ EK A PEE+ + + K +++ + L +E + + +K ++ QK+ +
Sbjct: 951 APEKKDTKEEK---AKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKP 1007
Query: 658 EERRYYEEERK 668
E+ ++ K
Sbjct: 1008 PEKATEDKAAK 1018
Score = 46.6 bits (109), Expect = 1e-04
Identities = 88/454 (19%), Positives = 164/454 (36%), Gaps = 31/454 (6%)
Query: 60 QTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMS---ARRTSHGEPKSAVPFNQYL 116
+ SP+ + + S +E+ P + VK++ S A+ E KS
Sbjct: 577 EVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPE 636
Query: 117 PNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFD 176
KS +P + K E+EE KS A SP+ E ++PV +A+S
Sbjct: 637 KAKSPTKEEAKSPEKAKSPEKEE-AKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK 695
Query: 177 MRCEEEA--------AVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDL 228
+EEA V+ +++ ++ + + + + KS ++ S +
Sbjct: 696 SPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEK 755
Query: 229 IKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGI 288
K + + K A E+ S K + + V+E+ + + K E E
Sbjct: 756 AKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIP 815
Query: 289 LQQYIERFTISEAVLERL---EMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKF 345
++ ++ E + + E PK E + + D + ++++ P PK
Sbjct: 816 KKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEA-PKPKV 874
Query: 346 TATVETTIARASVLDTSMSAGSGSPSKTV-TP--KAVPMLTPKPYSQPKNSQDVLKTFKV 402
E + + K V TP +A + K ++PK +V K
Sbjct: 875 EEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPD 934
Query: 403 DGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINI 462
D K +E K E AP TK + + + + K+D+ ++
Sbjct: 935 DAKA--------KEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEP 986
Query: 463 KKPNSVPQELAATTE----KTEPNSQEDKNDGGK 492
KP + E +++T+ K + EDK GK
Sbjct: 987 SKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 32.0 bits (71), Expect = 2.7
Identities = 22/82 (26%), Positives = 42/82 (51%), Gaps = 8/82 (9%)
Query: 587 LPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKE 646
+P++++ + S EK V+ + E+ + Q E+ ++ +E ++E+ + KE
Sbjct: 429 IPSVSTHIKVKSEEKIKVV--------EKSEKETVIVEEQTEETQVTEEVTEEEEKEAKE 480
Query: 647 EWEKAQKEVEEEERRYYEEERK 668
E K ++ EEEE EEE K
Sbjct: 481 EEGKEEEGGEEEEAEGGEEETK 502
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 56.2 bits (134), Expect = 1e-07
Identities = 147/710 (20%), Positives = 260/710 (36%), Gaps = 125/710 (17%)
Query: 185 VQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKK-EEERKKMEKLLA 243
V R +E+ + QL + W + R + ++ K+ EE+R+K E+ A
Sbjct: 63 VDDRQRLARERREEREKQLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRA 122
Query: 244 G-EDGTSERRKSIKTYREIV----QEKERRERELHEAYKNARSQEEAEGILQQYIERFTI 298
E+ +R + K E V E+ ++ ++ H + S + I +R ++
Sbjct: 123 AVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWSWGGSLHGSPSIHSADPDRRSV 182
Query: 299 SEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASV 358
S L + P I +R S+ L LN P+ + L+ L P + + S
Sbjct: 183 STMNLSKYVDPVISKRLSSSSATL---LNSPDRARRLQ---LSPWESSVVNRLLTPTHSF 236
Query: 359 LDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHR--- 415
L S S + S P++ P + +NS D K F + S +H
Sbjct: 237 LARSKSTAALSGEAA---SCSPIIMPYKAAHSRNSMDRPKLFVTPPEGSSRRRIIHGTAS 293
Query: 416 -EEEKERE-------------CPTVAPAHSLTKSQMF---EGVARVHGSPLELKQ-DNGS 457
++E+ERE P+ A +S+++ + + + G+P GS
Sbjct: 294 YKKERERENVLFLTSGTRRAVSPSNPKARQPARSRLWLPSKSLPHLPGTPRPTSSLPPGS 353
Query: 458 IEI---NIKKPNS-----VPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFT 509
++ ++ P+ V +E+ EK +P + K S KG L E
Sbjct: 354 VKAAPAQVRPPSPGNIRPVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVEE---- 409
Query: 510 TTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEA 569
TV EE+ +PE + P S A
Sbjct: 410 ATV-----------------------EERTPAEPEVGPAAPAMAPAPASAPAPASAPAPA 446
Query: 570 TLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEE------ERRRQE 623
+ P + P +S V++ +S K+ T DPEE E+RR
Sbjct: 447 PVPTPAMVSAP----------SSTVNASASVKTSAGTT------DPEEATRLLAEKRRLA 490
Query: 624 KWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKI-IEDTVVPFTVSSS 682
+ Q+E+E + R Q+E ++ K E E AQ+ EE R EE R++ E
Sbjct: 491 REQREKEER-ERREQEELERQKRE-ELAQRVAEERTTRREEESRRLEAEQAREKEEQLQR 548
Query: 683 SADQLSTSSSMTEGSGTMNKIDLGNCQDE----KQDRRWKKSFQGDDSDLLLKTRESDRL 738
A++ + K + ++E +Q+R +K FQ ++ + L + + + +
Sbjct: 549 QAEERALREREEAERAQRQKEEEARVREEAERVRQER--EKHFQREEQERLERKKRLEEI 606
Query: 739 EEKGSLTEGALAHSGN----PVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNP 794
++ TE + + ++KG TE A C TN P + +P
Sbjct: 607 MKRTRRTEATDKKTSDQRNGDIAKGALTG---GTEVSALPCTTNA-----PGNGKPVGSP 658
Query: 795 ----THSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLG 840
+H S+ T L+K P+E S+ + LP+G
Sbjct: 659 HVVTSHQSKVTVESTPDLEK-------QPNENGVSVQNENFEEIINLPIG 701
Score = 34.3 bits (77), Expect = 0.54
Identities = 24/106 (22%), Positives = 47/106 (44%), Gaps = 5/106 (4%)
Query: 181 EEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEK 240
+ A + +R +E +L Q RE++++ Q R R ++ +R+K E+
Sbjct: 517 QRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREEAE-----RAQRQKEEE 571
Query: 241 LLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAE 286
E+ R++ K ++ QE+ R++ L E K R E +
Sbjct: 572 ARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATD 617
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 55.5 bits (132), Expect = 2e-07
Identities = 153/791 (19%), Positives = 312/791 (39%), Gaps = 137/791 (17%)
Query: 4 ERQVKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPS 63
E+ +T+D E ++++RD DSE LS D S SL G ++TPS
Sbjct: 437 EQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTADASNGSLR--GLSGQRTPS 494
Query: 64 PDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQT 123
P R SS GRG R+ P A + S+
Sbjct: 495 PP---RRSSPGRG-----------------------RSPRRGPSPAC-------SDSSTL 521
Query: 124 AYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFD-----MR 178
A + + L K++ + ++ R + + LG R +SD + +R
Sbjct: 522 ALIHSALHKRQLQVQDMRGRYEASQDLLG-------TLRKQLSDSESERRALEEQLQRLR 574
Query: 179 CEEEAAVQPHSRARQE--QLQLINNQLREEDD---------KWQDDLARWKSRRRSVSQD 227
+ + A+Q H A++E +L+ N L E + Q + R + + +Q+
Sbjct: 575 DKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQE 634
Query: 228 LIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRE------RELHEAYKNARS 281
++++ +R + E+ A +DG RR+ +++R++ Q + +R E+ EA A
Sbjct: 635 ELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATL 694
Query: 282 QEEAEGILQQYIERFTISEAVLE----RLEMPKILERSHSTEPNLSSFLNDPNPM-KYLR 336
Q + +LQ E+ ++EA+ + R+E+ + + + E +L L+ + + + L
Sbjct: 695 QRD---MLQ--AEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLA 749
Query: 337 QQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDV 396
Q L + A L+ SA G + V + + + Q+V
Sbjct: 750 QDKLDLNRLVAQ----------LEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEV 799
Query: 397 LKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDN- 455
+ ++G + V + +E E++ PT+ S + Q+ + ++ G EL+Q
Sbjct: 800 ARQ-GLEGSLRVAEQA---QEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARR 855
Query: 456 ------GSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFT 509
++E ++ ++ +E A + +E + ++ + +E + E F
Sbjct: 856 EAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFE 915
Query: 510 TTVTRCSPTVAFVEFPSSPQ--------LKNDVSEEKDQKKPENEMSGKVELVLSQKVVK 561
+ + Q L +++ + Q E + + +++QK+V+
Sbjct: 916 VQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQ 975
Query: 562 PKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRR 621
+ E +A+L + A++ L L + ++ W E +
Sbjct: 976 AER-EAQASLR-----EQRAAHEEDLQRLQREKEAA-------------WRELEAERAQL 1016
Query: 622 QEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSS 681
Q + Q+EQE LL R + E+++L EE Q+E +E ++ ++ +S
Sbjct: 1017 QSQLQREQEELL-ARLEAEKEELSEEIAALQQE---------RDEGLLLAESEKQQALSL 1066
Query: 682 SSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEK 741
+++ + S + GT + + + + E+Q R + + D S + T E L +
Sbjct: 1067 KESEKTALSEKL---MGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDL--R 1121
Query: 742 GSLTEGALAHS 752
E A AH+
Sbjct: 1122 AQREEAAAAHA 1132
>gi|238908501 sciellin isoform 3 [Homo sapiens]
Length = 646
Score = 54.7 bits (130), Expect = 4e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 722 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 776
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 481 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 531
Query: 777 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 835
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 532 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 582
Query: 836 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 892
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 583 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 639
>gi|238908499 sciellin isoform 1 [Homo sapiens]
Length = 688
Score = 54.7 bits (130), Expect = 4e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 722 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 776
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 523 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 573
Query: 777 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 835
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 574 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 624
Query: 836 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 892
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 625 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 681
>gi|238908497 sciellin isoform 2 [Homo sapiens]
Length = 668
Score = 54.7 bits (130), Expect = 4e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 722 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 776
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 503 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 553
Query: 777 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 835
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 554 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 604
Query: 836 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 892
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 605 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 661
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 53.5 bits (127), Expect = 9e-07
Identities = 122/602 (20%), Positives = 235/602 (39%), Gaps = 105/602 (17%)
Query: 190 RARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTS 249
+ R +L Q +E ++++A ++ + +S S +L ++ +E+ L+ D
Sbjct: 293 KCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLS--DIEE 350
Query: 250 ERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAV-LERLEM 308
+ +Y++ +Q+ E R ++ E L++Y + + A+ +E
Sbjct: 351 RHNHDLSSYQDTIQQLENELRG---------TKWEMARHLREYQDLLNVKMALDIEIAAY 401
Query: 309 PKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSG 368
K+LE E S+F Y + PP T+ + I + V
Sbjct: 402 RKLLE---GEETRFSTFAGSITGPLYTHR----PP---ITISSKIQKPKV---------E 442
Query: 369 SPSKTVTPKAVPMLTPKPYSQPKNSQ--DVLKTFKVDGKVSVNGETVHREEEKERECPTV 426
+P V K V + + + + S+ + L + VS+ E EEKE E
Sbjct: 443 APKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAE 502
Query: 427 APAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQED 486
+ KS V + E+K++ G E + ++ A +++ E
Sbjct: 503 EEEVAAKKSP-------VKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE------ 549
Query: 487 KNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPEN- 545
+GG ++G+ E E + E + + + + +E K++KK E
Sbjct: 550 --EGGSEKEGSSEKEEGEQE----------------EGETEAEAEGEEAEAKEEKKVEEK 591
Query: 546 --EMSGKVELVLSQKVVKP---KSPEPEATLTFPF---LDKMPEANQLHLPNLNSQVD-- 595
E++ K ELV KV KP KSP P++ + + K P + P S V+
Sbjct: 592 SEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 651
Query: 596 -------SPSSE--KSPV-MTPFKFWAWDP------EEERRRQE--KWQQEQERLLQERY 637
SP E KSPV +P + A P EE + + E K +Q++E + +
Sbjct: 652 GKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKE 711
Query: 638 QKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTV-------SSSSADQLSTS 690
+++K++++ EK + E+++ +E + E + +V + L
Sbjct: 712 APKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQE 771
Query: 691 SSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQG-----DDSDLLLKTRESDRLEEKGSLT 745
+ G + G+ + K R+ + G ++ + K + S R EEKG +T
Sbjct: 772 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVT 831
Query: 746 EG 747
G
Sbjct: 832 NG 833
Score = 45.8 bits (107), Expect = 2e-04
Identities = 78/362 (21%), Positives = 150/362 (41%), Gaps = 42/362 (11%)
Query: 165 VSDDAESTSMFDMRCEEEAAVQPHSR----ARQEQLQLINNQLREEDDKWQDDLARWKSR 220
V + E T + D + E E A+ + + +E+ + + EE + ++++A KS
Sbjct: 453 VEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSP 512
Query: 221 RRS----VSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAY 276
++ V ++ +KEEE + E+ E S++ + + +E EKE E+E E
Sbjct: 513 VKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE 572
Query: 277 KNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTE-PNLSSFLND------- 328
A EEAE ++ +E + A E L +E+ + P S + +
Sbjct: 573 AEAEG-EEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP 631
Query: 329 PNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYS 388
+P++ + +P ++ + ++ V + S S SP V KA + P
Sbjct: 632 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSP---VEEKAKSPVPKSPVE 688
Query: 389 QPKNSQDVLK-----TFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVAR 443
+ K+ +V K + + K + E V ++EEK ++ P A S K + V
Sbjct: 689 EAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVT 748
Query: 444 VHGSPLELKQDNGSIEINIKKPNS-----VPQELAATTEKTEPNSQEDKNDGGK--SRKG 496
+ S++++++K + QE E S+E+ +D G SRK
Sbjct: 749 I----------TKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKE 798
Query: 497 NI 498
+I
Sbjct: 799 DI 800
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 53.5 bits (127), Expect = 9e-07
Identities = 83/427 (19%), Positives = 170/427 (39%), Gaps = 62/427 (14%)
Query: 416 EEEKERECPTVAPAH-SLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAA 474
E +KE + PT+ A SL +M A + E K ++ I++ +V +
Sbjct: 116 ERQKEFD-PTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQK 174
Query: 475 TTEK-TEPNSQEDKN----DGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQ 529
+ E N +EDK + K ++G+I E T TV
Sbjct: 175 NDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVM-------S 227
Query: 530 LKNDVSEEKDQKKPENEMSGKVELVLSQKVV---KPKSPEPEATLTFPFLDKMPEANQLH 586
LKN ++ K+ E G E+ +K+ K ++ A L +++
Sbjct: 228 LKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKK 287
Query: 587 LPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKE 646
+ + +++++ EK+ +ER R+E ++E+ R ++R +E+ ++KE
Sbjct: 288 IADERARIEA--EEKAAA------------QERERREAEERERMREEEKRAAEERQRIKE 333
Query: 647 EWEKAQKE---VEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKI 703
E ++A +E ++EEE+R EE ++I E+ +A++ + + E + +
Sbjct: 334 EEKRAAEERQRIKEEEKRAAEERQRIKEE-------EKRAAEERQRARAEEEEKAKVEEQ 386
Query: 704 DLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHED 763
+EK+ + +G+ ++E+K G V++ ++
Sbjct: 387 KRNKQLEEKKHAMQETKIKGE------------KVEQK---------IEGKWVNEKKAQE 425
Query: 764 HQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERR 823
+L T Q + Q PT E++K + + DK +++S +R+
Sbjct: 426 DKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRK 485
Query: 824 KSISGKK 830
K + K
Sbjct: 486 KGFTEVK 492
Score = 51.2 bits (121), Expect = 4e-06
Identities = 66/280 (23%), Positives = 116/280 (41%), Gaps = 45/280 (16%)
Query: 416 EEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAAT 475
EEE RE A L + Q E + +V +E+N + NSVP E A T
Sbjct: 34 EEEAARERRRRARQERLRQKQEEESLGQV----------TDQVEVNAQ--NSVPDEEAKT 81
Query: 476 TEKTEPNSQEDKNDGG----------KSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFP 525
T N+Q + +D + R+ ++ A + F T+T S ++
Sbjct: 82 TTT---NTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLP----- 133
Query: 526 SSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFL---DKMPEA 582
S +++ND +E + +K E S + + + KS + DK E
Sbjct: 134 -SRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEE 192
Query: 583 NQLHLPNLNS----QVD------SPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERL 632
+ P S QV+ + S++ V+ K EE ++ +E+ +Q + +
Sbjct: 193 EEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEER-EQGSDEI 251
Query: 633 LQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 672
+E+DK + E E+A+ E EE ER E+++KI ++
Sbjct: 252 SHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADE 291
Score = 47.4 bits (111), Expect = 6e-05
Identities = 109/573 (19%), Positives = 214/573 (37%), Gaps = 88/573 (15%)
Query: 180 EEEAAVQPHSRARQEQLQ-------------------------------LINNQLREEDD 208
EEEAA + RARQE+L+ N Q+ +D+
Sbjct: 34 EEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDE 93
Query: 209 K-WQDDLARWKSRRRSVSQDLIKKEEE-------------RKKMEKLLAGEDGTSERRKS 254
+ + LAR + RR+ Q+ +++++E ++M+ A + T + KS
Sbjct: 94 AAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKS 153
Query: 255 -IKTYREIVQEKER-----RERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEM 308
+ R ++E E ++ + +A +N + +E E ++ +R +I E +E +
Sbjct: 154 ESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVE 213
Query: 309 PKILERSHSTE----PNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMS 364
K E T N +P + Q S E RA +
Sbjct: 214 EKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLE 273
Query: 365 AGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECP 424
A K K + + ++ K + + + + + + E EE++R
Sbjct: 274 AEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKE 333
Query: 425 TVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQ 484
A + ++ E R +K++ ++ + +E A E+
Sbjct: 334 EEKRAAE-ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQL 392
Query: 485 EDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPT-VAFVEFPSSPQLKNDVSEEKDQKKP 543
E+K + K E + + + + + K + K +K
Sbjct: 393 EEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQ 452
Query: 544 ENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMP-------------------EANQ 584
E++ + K E + +K+ K K P+ E F+D+ N
Sbjct: 453 EDKPTFKKEEIKDEKIKKDKEPKEEVK---SFMDRKKGFTEVKSQNGEFMTHKLKHTENT 509
Query: 585 LHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQK---EQ 641
P + VD+ +E +P + K EE RRR+ + + E+ L+++ Q+ E
Sbjct: 510 FSRPGGRASVDTKEAEGAPQVEAGKRL----EELRRRRGETESEEFEKLKQKQQEAALEL 565
Query: 642 DKLKEEWEKAQKEVEEEERRYYEEE--RKIIED 672
++LK++ E+ +K +EEEE+R +EE RK+ E+
Sbjct: 566 EELKKKREERRKVLEEEEQRRKQEEADRKLREE 598
Score = 46.6 bits (109), Expect = 1e-04
Identities = 122/612 (19%), Positives = 232/612 (37%), Gaps = 128/612 (20%)
Query: 77 SDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRK---- 132
+D+ LP R++ ++D + T+ E KS +Y + +T V +K
Sbjct: 126 TDASLSLPSRRM----QNDTAENETTEKEEKSESRQERY---EIEETETVTKSYQKNDWR 178
Query: 133 -----KKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 187
KK ++E+ + GE ++ E T + ++ + ++ +P
Sbjct: 179 DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEP 238
Query: 188 HSRARQEQL--QLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGE 245
+EQ ++ +++ EE+DK + + R +R + ++ IK E+++K +
Sbjct: 239 KQEEEREQGSDEISHHEKMEEEDKERAEAER--ARLEAEERERIKAEQDKKIAD------ 290
Query: 246 DGTSERRKSIKTYREIVQEKERRERELHEAYKNA--RSQEEAEGILQQYIERFTISEAVL 303
ER + + QE+ERRE E E + R+ EE + I ++ A
Sbjct: 291 ----ERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEE------KRAAE 340
Query: 304 ERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSM 363
ER + + E + E +Q + + A E ARA
Sbjct: 341 ERQRIKE--EEKRAAE----------------ERQRIKEEEKRAAEERQRARAE------ 376
Query: 364 SAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKEREC 423
+K K L K ++ + +K KV+ K+ G+ V+ ++ +E +
Sbjct: 377 ---EEEKAKVEEQKRNKQLEEKKHAMQETK---IKGEKVEQKIE--GKWVNEKKAQEDKL 428
Query: 424 PTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNS 483
T ++ K Q E +V +L++D KP +E+ K +
Sbjct: 429 QT-----AVLKKQGEEKGTKVQAKREKLQED---------KPTFKKEEIKDEKIKKDKEP 474
Query: 484 QEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKP 543
+E+ +KG E+ S + T + T S P + V ++ + P
Sbjct: 475 KEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTF------SRPGGRASVDTKEAEGAP 528
Query: 544 ENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSP 603
+ E ++E ++ + E E+ K EA
Sbjct: 529 QVEAGKRLE------ELRRRRGETESEEFEKLKQKQQEA--------------------- 561
Query: 604 VMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQD-KLKEEWEKAQKEVEEEERR- 661
A + EE ++++E+ ++ E Q R Q+E D KL+EE EK + + E E RR
Sbjct: 562 --------ALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRA 613
Query: 662 -YYEEERKIIED 672
E+ +K+ ED
Sbjct: 614 EAAEKRQKMPED 625
Score = 35.0 bits (79), Expect = 0.31
Identities = 43/206 (20%), Positives = 86/206 (41%), Gaps = 23/206 (11%)
Query: 614 DPEEERRRQEKWQQEQERLLQER--YQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIE 671
D E RR + ++E+ RL ER YQ+ D +E + ++ +E R +EE + +
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 672 DT-VVPFTVSSSSADQ---LSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGD--- 724
T V +S D+ +T+++ EG ++ ++E++ +R +++ +
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEF 121
Query: 725 -----DSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQL-DTEAGAPHCGTN 778
D+ L L +R + TE S+ E +++ +TE N
Sbjct: 122 DPTITDASLSLPSRRMQNDTAENETTE------KEEKSESRQERYEIEETETVTKSYQKN 175
Query: 779 PQLAQDPSQNQQTSNPTHSSEDVKPK 804
+D +N++ E+ KPK
Sbjct: 176 DW--RDAEENKKEDKEKEEEEEEKPK 199
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 52.8 bits (125), Expect = 1e-06
Identities = 101/480 (21%), Positives = 181/480 (37%), Gaps = 74/480 (15%)
Query: 231 KEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERR-----ERELHEAYKNARSQEEA 285
K +ER+++ K + ER K + + + EK++R E+++ E ++ Q +
Sbjct: 50 KSDERQRLAK-----ERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQR 104
Query: 286 EGILQQYIE--RFTISEAVLERLE--MPKILERSHSTEPNLSSFLNDP---NPMKYLRQQ 338
E + +E R ERLE M + LER+ E P P +
Sbjct: 105 EDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKYSWGAPLAIGPGGHDACD 164
Query: 339 SLPPPKFTATVETTIARASVLDTSMSAGSGSPSKT--VTPKAVPM--LTPKPYSQPKNSQ 394
L + T L +S A S SP + V P+ P+ L P S P +
Sbjct: 165 KLSTSTMSLPKPTEPPMNKRLSSSTVAISYSPDRVFHVCPRLAPLGPLNPSYKSSPTRNI 224
Query: 395 DVLKTFKVD-------GKVSVNG------ETVHREEEKERECPTVAPAHSLTKSQMFEGV 441
+ K GK +++G E V R + P V L + + G+
Sbjct: 225 EKKKATSTSTSGAGDVGKEALSGGEASLVEKVKRGQRTATSLPVVNFGSPLRRCEFSGGI 284
Query: 442 ARVHGSPLELKQDNGSIEINIK--KP----NSVPQELAATTEKTEPNSQEDKNDGGKSRK 495
+ SP+ K + + K KP + V L A + + P + +K K R+
Sbjct: 285 PKRPSSPVISKTATKAYPQSPKTTKPPYPGSPVKYRLPALSGQDMPKRKAEKEKSNKERE 344
Query: 496 GNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVL 555
G + ++ PQ L+ V ++ +K GK E
Sbjct: 345 GTLAQQAAGPQ-------------------GEEALEKHVVDKHASEKHAAAAGGKAEN-- 383
Query: 556 SQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDP 615
S + KP + +A L + + Q L + + E+ D
Sbjct: 384 SAALGKPTAGTTDAGEAAKILAE--KRRQARLQKEQEEQERVEKEEQ-----------DR 430
Query: 616 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVV 675
E + K ++E+ RL +E ++E+++ ++E EK ++E EE+ + E +RK E+ ++
Sbjct: 431 LEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLL 490
Score = 46.6 bits (109), Expect = 1e-04
Identities = 68/314 (21%), Positives = 127/314 (40%), Gaps = 41/314 (13%)
Query: 57 RSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYL 116
R ++T + V+ S R + +P R P +A + PK+ P
Sbjct: 258 RGQRTATSLPVVNFGSPLRRCEFSGGIPKR--PSSPVISKTATKAYPQSPKTTKPPYPGS 315
Query: 117 PNKSNQTAYVPAPLRKKKAEREEYRKSWS-----TATSPLGGERPFRYGPRTPVSDD--- 168
P K A + K+KAE+E+ K A P G E ++ S+
Sbjct: 316 PVKYRLPALSGQDMPKRKAEKEKSNKEREGTLAQQAAGPQGEEALEKHVVDKHASEKHAA 375
Query: 169 -----AESTSMFDMRCEE-----EAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWK 218
AE+++ EAA + RQ +LQ + + + QD L R +
Sbjct: 376 AAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREE 435
Query: 219 SRRRS------VSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQE---KERRE 269
+R++ + ++ K+EEERK+ E+ ++G +R+ + R+ +E KE++E
Sbjct: 436 LKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQE 495
Query: 270 RELHEAYKNARSQEEAEGILQQYIERFTIS-EAVLERLEMPKILERSHSTEPNLSSFLND 328
+E E + +E AE ++ E+ + E ++ ++E ++ + E
Sbjct: 496 QEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQERLERKKRIDE--------- 546
Query: 329 PNPMKYLRQQSLPP 342
MK R+ +PP
Sbjct: 547 --IMKRTRKSDVPP 558
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 51.6 bits (122), Expect = 3e-06
Identities = 98/511 (19%), Positives = 196/511 (38%), Gaps = 70/511 (13%)
Query: 178 RCEEEAAVQPHS-RARQEQLQLINNQLREEDDKWQDD---LARWKSRRRSVSQDLIKKEE 233
R EEE Q R ++E++ +LRE++ K ++ + R + R R ++L ++E+
Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK 297
Query: 234 ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE----RRERELHEAYKNARSQEEAEGIL 289
E ++ +KL E+ E+ + + E ++E+E R+E L E K R QE + +
Sbjct: 298 ELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE--QKMR 355
Query: 290 QQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATV 349
Q + E + E+ E + E+ E + K +R++
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE---------- 405
Query: 350 ETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVN 409
ET + + K + +P K + Q K + K ++ + K+
Sbjct: 406 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 465
Query: 410 GETVHRE-----EEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKK 464
E +E +EK RE + QM+E ++ ++ +
Sbjct: 466 EEMWGQEKKMWRQEKMRE----------QEDQMWEQEEKMRDQEQKMWDQEERM------ 509
Query: 465 PNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEF 524
E + E +E K + K E + E + T +
Sbjct: 510 -----WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW------------DQ 552
Query: 525 PSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQ 584
+ + + E + + + E EM + E + ++ K + E + + +KM E +
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM---WEQEEKMQEQEE 609
Query: 585 LHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEK--WQQEQERLLQERYQKEQD 642
+ +K M + W+ EE+ + QE+ W+QE++ QE +EQ+
Sbjct: 610 KMWEQEEKMWEQEEEDK---MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 666
Query: 643 KLKEEWEKAQKEVEE----EERRYYEEERKI 669
+ + E+ +E EE +E + E+E K+
Sbjct: 667 EKMQGQEEKMREQEEKMQGQEEKMREQEEKM 697
Score = 51.6 bits (122), Expect = 3e-06
Identities = 98/510 (19%), Positives = 201/510 (39%), Gaps = 75/510 (14%)
Query: 177 MRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERK 236
+R +EE + R R+++ ++RE+++K + R + R R ++L ++E+E +
Sbjct: 250 IRKQEEKMWRQEERLREQE-----GKMREQEEK----MRRQEKRLREQEKELREQEKELR 300
Query: 237 KMEKLLAGEDGTSERRKSIKTYREIVQEKE----RRERELHEAYKNARSQEEAEGILQQY 292
+ +KL E+ E+ + + E ++E+E R+E L E K R QE+ + Q
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK--MRDQE 358
Query: 293 IERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETT 352
+ E + E+ E + E+ E + K +R++ ET
Sbjct: 359 ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE----------ETM 408
Query: 353 IARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGET 412
+ + K + +P K + Q K + K ++ + K+ E
Sbjct: 409 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 468
Query: 413 VHRE-----EEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSI---EINIKK 464
+E +EK RE + QM+E ++ ++ + + +++
Sbjct: 469 WGQEKKMWRQEKMRE----------QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE 518
Query: 465 PNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFV-E 523
+E ++ E +E K + + + E E + + + E
Sbjct: 519 KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 578
Query: 524 FPSSPQLKNDVSEEKDQK--KPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPE 581
Q + + E+++K + E +M + E + Q+ + E DKM E
Sbjct: 579 QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE---------DKMQE 629
Query: 582 ANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQ 641
++ E+ M + W+ EE+ R QE+ +EQE E+ Q ++
Sbjct: 630 QEEM------------MWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE----EKMQGQE 673
Query: 642 DKLKEEWEKAQ----KEVEEEERRYYEEER 667
+K++E+ EK Q K E+EE+ +EE+
Sbjct: 674 EKMREQEEKMQGQEEKMREQEEKMRGQEEK 703
Score = 47.4 bits (111), Expect = 6e-05
Identities = 35/141 (24%), Positives = 68/141 (48%), Gaps = 18/141 (12%)
Query: 613 WDPEEERRRQEK--WQQE-----QERLLQERYQKEQDKLKEEWEKAQKEVEEEER----- 660
W+ EE+ R QE+ W+QE QE+ ++E+ QK +D+ + WE+ ++ E+EER
Sbjct: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379
Query: 661 RYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKS 720
+ +E+E K+ E+ + +M E M K + E++++ W++
Sbjct: 380 KMWEQEEKMQEEE----RIREREKKMREEEETMREQEEKMQKQE--ENMWEQEEKEWQQQ 433
Query: 721 FQGDDSDLLLKTRESDRLEEK 741
+ + L + + EEK
Sbjct: 434 RLPEQKEKLWEQEKMQEQEEK 454
Score = 42.0 bits (97), Expect = 0.003
Identities = 31/132 (23%), Positives = 64/132 (48%), Gaps = 14/132 (10%)
Query: 613 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKA---QKEVEEEERRYYEEERKI 669
W+ +E R +E+ +EQ+++ Q+ + ++K +E EK Q+E EE R E E+K+
Sbjct: 510 WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKM 569
Query: 670 IEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLL 729
E+ + +Q M E M + Q+EK + +K ++ ++ +
Sbjct: 570 REEEEMMREQEEKMQEQ---EEKMREQEEKMWE------QEEKMQEQEEKMWEQEEK--M 618
Query: 730 LKTRESDRLEEK 741
+ E D+++E+
Sbjct: 619 WEQEEEDKMQEQ 630
Score = 41.2 bits (95), Expect = 0.004
Identities = 38/140 (27%), Positives = 61/140 (43%), Gaps = 13/140 (9%)
Query: 545 NEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQV--------DS 596
NE K L +K+ +S + E L L + E + LP + + +
Sbjct: 182 NEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 241
Query: 597 PSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLL--QERYQKEQDKLKEEWEK---A 651
E+ + + W EE R QE +EQE + QE+ +EQ+K E EK
Sbjct: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301
Query: 652 QKEVEEEERRYYEEERKIIE 671
QK++ E+E + E+E K+ E
Sbjct: 302 QKKLREQEEQMQEQEEKMWE 321
Score = 39.7 bits (91), Expect = 0.013
Identities = 24/71 (33%), Positives = 44/71 (61%), Gaps = 11/71 (15%)
Query: 613 WDPEEERRRQEK--WQQEQ------ERLLQ-ERYQKEQDKL--KEEWEKAQKEVEEEERR 661
W+ EE+ R QE+ W QE+ ERL + E +EQ K+ +EE + +K+ +E+E++
Sbjct: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK 548
Query: 662 YYEEERKIIED 672
+++E K+ E+
Sbjct: 549 TWDQEEKMREE 559
Score = 38.9 bits (89), Expect = 0.022
Identities = 34/129 (26%), Positives = 61/129 (47%), Gaps = 11/129 (8%)
Query: 614 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRY-YEEERKIIED 672
+ EE R QE+ QEQE ++E+ +K ++ ++ E+ +K E+EE+ + EEE K+ E
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQ 630
Query: 673 TVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKT 732
+ + +Q M E M + Q+EK R ++ QG + + +
Sbjct: 631 EEMMWEQEEKMQEQ---EEKMWEQEEKMRE------QEEKM-REQEEKMQGQEEKMREQE 680
Query: 733 RESDRLEEK 741
+ EEK
Sbjct: 681 EKMQGQEEK 689
Score = 37.7 bits (86), Expect = 0.049
Identities = 36/142 (25%), Positives = 65/142 (45%), Gaps = 19/142 (13%)
Query: 536 EEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVD 595
EEK QK+ EN + + Q++ + K E +K+ E + + Q +
Sbjct: 412 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE----KIRDQEE 467
Query: 596 SPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEV 655
EK K W +E+ R QE EQE ++++ QK D+ + WE+ ++
Sbjct: 468 MWGQEK-------KMWR---QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLR 517
Query: 656 EEEER-----RYYEEERKIIED 672
E+EER + +++E K+ E+
Sbjct: 518 EKEERMREQKKMWQQEEKMREE 539
Score = 37.0 bits (84), Expect = 0.083
Identities = 34/143 (23%), Positives = 61/143 (42%), Gaps = 26/143 (18%)
Query: 616 EEER-RRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEE-----------EERRYY 663
EEER R +EK +E+E ++E+ +K Q + + WE+ +KE ++ E+ +
Sbjct: 390 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 449
Query: 664 EEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQG 723
E+E KI E Q E G K+ E++D+ W++ +
Sbjct: 450 EQEEKIWE--------------QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 495
Query: 724 DDSDLLLKTRESDRLEEKGSLTE 746
D + + +E E+ L E
Sbjct: 496 RDQEQKMWDQEERMWEQDERLRE 518
Score = 36.2 bits (82), Expect = 0.14
Identities = 57/275 (20%), Positives = 113/275 (41%), Gaps = 39/275 (14%)
Query: 130 LRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHS 189
+R++K +E+ +K+W ER + ++ M+ +EE +
Sbjct: 536 MREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE 595
Query: 190 RA--RQEQLQLINNQL---------REEDDKWQD-DLARWKSRRRSVSQD--------LI 229
+ ++E++Q ++ +EE+DK Q+ + W+ + Q+ +
Sbjct: 596 KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM 655
Query: 230 KKEEE--RKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEG 287
+++EE R++ EK+ E+ E+ + ++ QE++ RE+E + R QEE
Sbjct: 656 REQEEKMREQEEKMQGQEEKMREQEEKMQG-----QEEKMREQE-----EKMRGQEEK-- 703
Query: 288 ILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTA 347
+ Q + + E + + EM + ER + + L P + + LPP K
Sbjct: 704 MWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERL--PEHEERCSEPCLPPSKVLC 761
Query: 348 TVETTIARASVLDTSMSAGSGSPSKTVTPKAVPML 382
+ T SV AG GSP T + + L
Sbjct: 762 NMSHT---GSVEPAGGEAGEGSPQDNPTAQEIMQL 793
Score = 35.8 bits (81), Expect = 0.18
Identities = 31/146 (21%), Positives = 64/146 (43%), Gaps = 10/146 (6%)
Query: 536 EEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVD 595
EE+D+ + + EM + E + ++ K E + + + E Q + Q +
Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
Query: 596 SPSSEKSPVMTPFKFWAWDPEEERRRQEK--WQQEQERLLQERYQKEQDKLKEEWEKAQK 653
++ + + EE+ R QE+ W QE++ QE Q++++E+ E+ +
Sbjct: 682 KMQGQEEKMR--------EQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRD 733
Query: 654 EVEEEERRYYEEERKIIEDTVVPFTV 679
+ E+ + R E E + E + P V
Sbjct: 734 QKEKMQERLPEHEERCSEPCLPPSKV 759
Score = 34.3 bits (77), Expect = 0.54
Identities = 17/59 (28%), Positives = 35/59 (59%)
Query: 614 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 672
+ EE+ + QE+ EQE ++E+ +K + + WE+ ++ E+E++ +EER +D
Sbjct: 307 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD 365
Score = 31.6 bits (70), Expect = 3.5
Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 9/107 (8%)
Query: 186 QPHSRARQEQLQLINNQLREEDDKWQDDLAR-WKSRRRSVSQDLIKKEEERKKM----EK 240
Q + QE++ +LRE++ K + + W+ R Q+ K E+ +KM ++
Sbjct: 226 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEG-KMREQEEKMRRQEKR 284
Query: 241 LLAGEDGTSERRKSI---KTYREIVQEKERRERELHEAYKNARSQEE 284
L E E+ K + K RE ++ + +E ++ E + R QEE
Sbjct: 285 LREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE 331
Score = 30.8 bits (68), Expect = 5.9
Identities = 33/138 (23%), Positives = 67/138 (48%), Gaps = 23/138 (16%)
Query: 193 QEQLQLINN-----QLREEDDKWQDDLARW---KSRRRSVSQDLIKKEEE--------RK 236
QE+L+L + QL ++ K + + A++ + + ++ +++ ++EEE RK
Sbjct: 193 QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRK 252
Query: 237 KMEKLLAGEDGTSERRKSIKTYREIVQEKERR----ERELHEAYKNARSQE---EAEGIL 289
+ EK+ E+ E+ ++ E ++ +E+R E+EL E K R Q+ E E +
Sbjct: 253 QEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQM 312
Query: 290 QQYIERFTISEAVLERLE 307
Q+ E+ E + E
Sbjct: 313 QEQEEKMWEQEEKMREQE 330
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 618 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 677
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 147 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 204
Query: 678 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 736
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 205 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 258
Query: 737 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 793
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 259 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 318
Query: 794 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 829
S+E+V + + D ++ NH + P R SG+
Sbjct: 319 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 358
Score = 39.3 bits (90), Expect = 0.017
Identities = 19/59 (32%), Positives = 37/59 (62%), Gaps = 6/59 (10%)
Query: 617 EERRRQEKWQ----QEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIE 671
++ +R+EKW+ +E+E ++R+++EQDK + EWE+ ++ E R + ER +E
Sbjct: 101 KDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRR--EMAREHSRRERDRLE 157
Score = 38.9 bits (89), Expect = 0.022
Identities = 38/122 (31%), Positives = 59/122 (48%), Gaps = 18/122 (14%)
Query: 173 SMFDMRCEEE--AAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSR------RRSV 224
SM D E++ A P +R+E++ ++ R+E KW+ AR K R R
Sbjct: 72 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKE--KWKH--ARVKEREHERRKRHRE 127
Query: 225 SQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEE 284
QD ++E ER+K ++ A E ER + E ++ K RER++ E K R Q+E
Sbjct: 128 EQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQKEQREQKE 181
Query: 285 AE 286
E
Sbjct: 182 RE 183
Score = 31.6 bits (70), Expect = 3.5
Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 7/91 (7%)
Query: 205 EEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQE 264
EEDD + SR+ V +K+E+RK+ K ++ ERR K +RE Q+
Sbjct: 78 EEDDSLAIKPPQQMSRKEKVHH---RKDEKRKEKWKHARVKEREHERR---KRHRE-EQD 130
Query: 265 KERRERELHEAYKNARSQEEAEGILQQYIER 295
K RRE E + + AR E + +ER
Sbjct: 131 KARREWERQKRREMAREHSRRERDRLEQLER 161
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 618 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 677
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 157 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 214
Query: 678 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 736
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 215 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 268
Query: 737 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 793
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 269 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 328
Query: 794 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 829
S+E+V + + D ++ NH + P R SG+
Sbjct: 329 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 368
Score = 33.9 bits (76), Expect = 0.70
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 218 KSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYK 277
+ +R QD ++E ER+K ++ A E ER + E ++ K RER++ E K
Sbjct: 131 RRKRHREEQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQK 184
Query: 278 NARSQEEAE 286
R Q+E E
Sbjct: 185 EQREQKERE 193
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 618 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 677
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 148 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 205
Query: 678 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 736
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 206 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 259
Query: 737 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 793
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 260 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 319
Query: 794 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 829
S+E+V + + D ++ NH + P R SG+
Sbjct: 320 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 359
Score = 35.4 bits (80), Expect = 0.24
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 11/119 (9%)
Query: 173 SMFDMRCEEE--AAVQPHSRARQEQLQLINNQLREEDDKW---QDDLARWKSRRRSVSQD 227
SM D E++ A P +R+E++ ++ R+E + + + +R QD
Sbjct: 72 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQD 131
Query: 228 LIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAE 286
++E ER+K ++ A E ER + E ++ K RER++ E K R Q+E E
Sbjct: 132 KARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQKEQREQKERE 184
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 618 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 677
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 125 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 182
Query: 678 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 736
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 183 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 236
Query: 737 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 793
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 237 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 296
Query: 794 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 829
S+E+V + + D ++ NH + P R SG+
Sbjct: 297 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 336
Score = 33.9 bits (76), Expect = 0.70
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 218 KSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYK 277
+ +R QD ++E ER+K ++ A E ER + E ++ K RER++ E K
Sbjct: 99 RRKRHREEQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQK 152
Query: 278 NARSQEEAE 286
R Q+E E
Sbjct: 153 EQREQKERE 161
Score = 30.8 bits (68), Expect = 5.9
Identities = 28/113 (24%), Positives = 51/113 (45%), Gaps = 8/113 (7%)
Query: 173 SMFDMRCEEE--AAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIK 230
SM D E++ A P +R+E++ ++ R+E + + A R ++
Sbjct: 38 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKE--- 94
Query: 231 KEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQE 283
+E ER+K + E + R + RE+ +E RRER+ E + R +E
Sbjct: 95 REHERRKRHR---EEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERE 144
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 618 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 677
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 114 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 171
Query: 678 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 736
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 172 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 225
Query: 737 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 793
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 226 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 285
Query: 794 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 829
S+E+V + + D ++ NH + P R SG+
Sbjct: 286 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 325
Score = 35.4 bits (80), Expect = 0.24
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 11/119 (9%)
Query: 173 SMFDMRCEEE--AAVQPHSRARQEQLQLINNQLREEDDKW---QDDLARWKSRRRSVSQD 227
SM D E++ A P +R+E++ ++ R+E + + + +R QD
Sbjct: 38 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQD 97
Query: 228 LIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAE 286
++E ER+K ++ A E ER + E ++ K RER++ E K R Q+E E
Sbjct: 98 KARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQKEQREQKERE 150
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 618 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 677
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 159 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 216
Query: 678 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 736
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 217 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 270
Query: 737 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 793
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 271 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 330
Query: 794 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 829
S+E+V + + D ++ NH + P R SG+
Sbjct: 331 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 370
Score = 33.9 bits (76), Expect = 0.70
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 218 KSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYK 277
+ +R QD ++E ER+K ++ A E ER + E ++ K RER++ E K
Sbjct: 133 RRKRHREEQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQK 186
Query: 278 NARSQEEAE 286
R Q+E E
Sbjct: 187 EQREQKERE 195
Score = 30.8 bits (68), Expect = 5.9
Identities = 28/113 (24%), Positives = 51/113 (45%), Gaps = 8/113 (7%)
Query: 173 SMFDMRCEEE--AAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIK 230
SM D E++ A P +R+E++ ++ R+E + + A R ++
Sbjct: 72 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKE--- 128
Query: 231 KEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQE 283
+E ER+K + E + R + RE+ +E RRER+ E + R +E
Sbjct: 129 REHERRKRHR---EEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERE 178
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 48.9 bits (115), Expect = 2e-05
Identities = 121/633 (19%), Positives = 251/633 (39%), Gaps = 64/633 (10%)
Query: 105 EPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTP 164
E + + +P + + L +KK + + R+ W + L + Y +
Sbjct: 1780 EKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNL 1839
Query: 165 VSDDAESTSMFDMRCE-EEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRS 223
+ + + +E + R + QL+ Q++ + + LA+ + +
Sbjct: 1840 AQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLV--QVKNKLGMFNKILAQVEEKLTQ 1897
Query: 224 VSQDLIKKEEERKKMEK-LLAGEDGTSERRKSIKTYR-------EIVQEKERRERELHEA 275
+ +IKK+E+ + EK L+ ED +++++ + + +VQ K+R EL A
Sbjct: 1898 EKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIA 1957
Query: 276 YKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYL 335
+ E + + ++ + R + L + E P+ + T+ F +
Sbjct: 1958 KEEKALNLEMKRLAEEKM-RLVEGKETLSKGETPETSRQRKMTQVEQELF---ERKLSLE 2013
Query: 336 RQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQD 395
+ L + A E+ IA+ L+ + + KA L K S K
Sbjct: 2014 EKILLHEDRILAMEESEIAKGK-LEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAK 2072
Query: 396 VLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVAR--VHGSPLELKQ 453
+ K K K++ + + +EE K + K +F R + S L++K+
Sbjct: 2073 LNKILKALQKLTRDERKLTQEEIKMTKM----------KRALFVKERRLSIEQSKLDIKE 2122
Query: 454 DNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVT 513
+ S +K + + ++ K + + + K K E + +H + +
Sbjct: 2123 WDFS-----EKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKH-SEVIL 2176
Query: 514 RCSPTVAFVEFPSSPQLKNDVSEEKDQK---KPENEMSGKVELVLSQKVVKPKSPEPEAT 570
E P LK + K+ K KP+ + S +V+ V S++ S E E+
Sbjct: 2177 DDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHF---SEEMES- 2232
Query: 571 LTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQE 630
LD++ + L + + E+ V + EEER+ +E+ +++Q
Sbjct: 2233 ----LLDELEKQESLSSEEEEEREEEEEREEEEVR--------EEEEERKEEEEGEEKQV 2280
Query: 631 RLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTS 690
++E++K K++ EK ++EV+E+E + E+E + E+ T S S ++ S
Sbjct: 2281 E------KEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEE----TESLSDEEEEEES 2330
Query: 691 SSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQG 723
S+ E +I Q + Q++R +KS +G
Sbjct: 2331 CSLEEEVDREKEILKKEKQFKLQEQR-RKSLRG 2362
Score = 38.5 bits (88), Expect = 0.028
Identities = 20/60 (33%), Positives = 39/60 (65%), Gaps = 3/60 (5%)
Query: 616 EEERRRQEKWQQEQERLLQERYQKEQDKLKEE---WEKAQKEVEEEERRYYEEERKIIED 672
E+++ + E+W+Q E +L + +++Q K +EE E+ +E EE+E++ EE+R I E+
Sbjct: 1512 EDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEE 1571
Score = 36.6 bits (83), Expect = 0.11
Identities = 34/147 (23%), Positives = 64/147 (43%), Gaps = 20/147 (13%)
Query: 534 VSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLP----- 588
V+ E+++ + +V+ +L+QKV + P+ E L + + E +L
Sbjct: 1672 VAREEEKLAKKGGKLAEVKNILAQKV--EELPQREQNLDWQEKELAQELEELEWDMEELS 1729
Query: 589 ----NLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKL 644
LN + EK + + AW E+ + K QE+E L+QE
Sbjct: 1730 WKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQE--------- 1780
Query: 645 KEEWEKAQKEVEEEERRYYEEERKIIE 671
KE+ + ++++ EEE R + ++IE
Sbjct: 1781 KEKLAQHKEKMPEEEERLGRKREQLIE 1807
Score = 36.6 bits (83), Expect = 0.11
Identities = 16/60 (26%), Positives = 38/60 (63%), Gaps = 2/60 (3%)
Query: 613 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 672
WD EE ++E+ QE+ +L++E+ + +++ W++ +++ EEE + +EE +I++
Sbjct: 1723 WDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQR--EKLSEEETKLAQEEELLIQE 1780
Score = 35.8 bits (81), Expect = 0.18
Identities = 43/175 (24%), Positives = 77/175 (44%), Gaps = 23/175 (13%)
Query: 590 LNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWE 649
L +V EK +T EE+R QE + + R+ ++R + E+ + +EE +
Sbjct: 1546 LEEEVSREGEEKEQQVT---------EEQRHIQE--EHKWARIHRKRARAEKKRAQEERK 1594
Query: 650 KAQKE--VEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGN 707
AQ+E + +EER+ +EERK+ + V ++ + + T+ +
Sbjct: 1595 LAQEEEKLAQEERQLAQEERKLAQAYV---KITQDDREMAQAEGKFAQKEETLAQ----- 1646
Query: 708 CQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHE 762
+ EK + +K Q L K + R EEK + G LA N +++ V E
Sbjct: 1647 -RGEKLSQEAEKLAQ-KRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEE 1699
Score = 34.3 bits (77), Expect = 0.54
Identities = 122/700 (17%), Positives = 261/700 (37%), Gaps = 85/700 (12%)
Query: 192 RQEQLQLINNQLREEDDKW--QDDLARWKSRRRSVSQDLIKKEEER--KKMEKLLAGEDG 247
++E+L +L EE K +++ W+ + S + + +EEE ++ EKL ++
Sbjct: 1731 KEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEK 1790
Query: 248 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 307
E + + RE + EK+ + + E + N+ +E + + Y ++ E E
Sbjct: 1791 MPEEEERLGRKREQLIEKKMKLAQKRERWINSM-EELTKNKMILYQKKNLAQEKKNLAQE 1849
Query: 308 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 367
K+ +R + N + + ++ + K A VE + +
Sbjct: 1850 KEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKL 1909
Query: 368 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 427
K + + + + + L+ V GK + GE +EEK
Sbjct: 1910 AETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEK-------- 1961
Query: 428 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNS--QE 485
A +L ++ E R+ L + +K V QEL E E
Sbjct: 1962 -ALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHE 2020
Query: 486 DK---NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKK 542
D+ + + KG +E + FV+ Q K + K KK
Sbjct: 2021 DRILAMEESEIAKGKLEFTRGQR--------------IFVQ----GQRKLAKASRKLIKK 2062
Query: 543 PEN--EMSGKVELVLS--QKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPS 598
E+ + K+ +L QK+ + + + + + + + L S++D
Sbjct: 2063 RESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKE 2122
Query: 599 ---SEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEV 655
SEK +T D ++ R+Q K + R++ + + +++ K + ++ +
Sbjct: 2123 WDFSEKRSELTK------DEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVIL 2176
Query: 656 EEEERRYYEEE------------RKIIEDTVVPFTVSSSSADQLSTSSSMTEG-SGTMNK 702
++EE EEE RK + P SS D++ + +E +++
Sbjct: 2177 DDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDE 2236
Query: 703 IDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHE 762
++ +++ ++ + ++ + ++ E +R EE+ EG V K E
Sbjct: 2237 LEKQESLSSEEEEEREEEEEREEEE--VREEEEERKEEE----EG----EEKQVEKEEEE 2286
Query: 763 DHQLDTEAGAPHCGTNPQLAQDPSQ-NQQTSNPTHSSEDVKPKTLPLDKSINH------- 814
+ E ++ ++ + + + S E+ + ++ L++ ++
Sbjct: 2287 KKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKK 2346
Query: 815 --QIESPSERRKSISGKKLCSSC--GLPLGKGAAMIIETL 850
Q + +RRKS+ G++ S G+P GKG A+ + L
Sbjct: 2347 EKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVL 2386
Score = 32.7 bits (73), Expect = 1.6
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 11/76 (14%)
Query: 609 KFW-AWDPEEERR---RQEKWQQEQERLLQERYQKEQDKL------KEEWEKAQKEVEEE 658
K W AW E E+R +EK Q E+L E ++DK K+ WE + +
Sbjct: 1476 KSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSS-KSK 1534
Query: 659 ERRYYEEERKIIEDTV 674
E++Y +EE +E+ V
Sbjct: 1535 EQQYKDEEEVTLEEEV 1550
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 48.5 bits (114), Expect = 3e-05
Identities = 128/637 (20%), Positives = 225/637 (35%), Gaps = 109/637 (17%)
Query: 134 KAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQ 193
K E EE R+ L E+ R R ++ E R E ++ R+
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEER---LQQRLRSEQQLRREQEERR 546
Query: 194 EQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERK----------KMEKLLA 243
EQL + R E ++ + L R + RR L+K+EEER+ ++E+ L
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRD---QLLKREEERRQQRLKREQEERLEQRLK 603
Query: 244 GEDGT---SERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISE 300
E+ E R+ + RE E+ERR++ L + R Q++ Q+ E+ E
Sbjct: 604 REEVERLEQEERREQRLKRE-EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Query: 301 AVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLD 360
ERLE + L+R H E + R +S P AR S
Sbjct: 663 EEEERLE--QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQS--- 717
Query: 361 TSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKE 420
K YS+P+ + + + + K R E E
Sbjct: 718 ------------------------KVYSRPRKQEGQRRRQEQEEK--------RRRRESE 745
Query: 421 RECPTVAPAHSLTKSQMFEGVAR--VHGSPLELKQDNGSIEINIKKPNSVPQELAATTEK 478
+ AH + Q E R E K + G ++ + P +E E+
Sbjct: 746 LQWQEEERAH---RQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEE 802
Query: 479 TE-------PNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLK 531
+ P +E + + R+ EL E + E +
Sbjct: 803 RQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE----------------EQLQRRERA 846
Query: 532 NDVSEEKDQKKPENEMSGKVELVLSQK----VVKPKSPEPEATLTFPFLDKMPEANQLHL 587
+ EE+D + + E E QK + + + P L + Q L
Sbjct: 847 QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLL 906
Query: 588 PNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQE---RLLQERYQKEQDKL 644
++ EK + + + + ++ ++ ++E+E R +ER ++ KL
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
Query: 645 KEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKID 704
+++ E+ E E E+RR E E+K E+ + +QL + +
Sbjct: 967 QQKEEQLLGE-EPEKRRRQEREKKYREEEEL-----QQEEEQL-----------LREERE 1009
Query: 705 LGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEK 741
Q+ ++ R K Q ++ LL + RE RL+E+
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
Score = 46.6 bits (109), Expect = 1e-04
Identities = 46/188 (24%), Positives = 77/188 (40%), Gaps = 33/188 (17%)
Query: 131 RKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHS- 189
++++ +R ++ W G + R R P+ + E + R + E P
Sbjct: 758 QQEEEQRRDFTWQWQAEEKSERGRQ--RLSARPPLREQRERQLRAEERQQREQRFLPEEE 815
Query: 190 ---------RARQEQLQLINN-----------QLREEDDKWQDDLARWKSRRRSVSQDLI 229
R R+++LQ + QL+EE+D Q+D + RRRS Q
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQED----QERRRSQEQRRD 871
Query: 230 KK-----EEERKKMEKLLAGEDGTSER-RKSIKTYREIVQEKERRERELHEAYKNARSQE 283
+K EEERK+ L + E+ RK + +E +E +R ERE + R
Sbjct: 872 QKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYR 931
Query: 284 EAEGILQQ 291
E E + Q+
Sbjct: 932 EEEQLQQE 939
Score = 44.7 bits (104), Expect = 4e-04
Identities = 33/127 (25%), Positives = 66/127 (51%), Gaps = 11/127 (8%)
Query: 176 DMRCEEEAAV--QPHSRARQEQLQLINNQLREEDDKWQDDLA-----RWKSRRRSVSQDL 228
+++ EEE + +P R RQE+ Q REE++ Q++ R K RR+ + +
Sbjct: 1085 ELQQEEEQLLREEPEKRRRQER----ERQCREEEELQQEEEQLLREEREKRRRQELERQY 1140
Query: 229 IKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGI 288
++EE +++ E+LL E R++ + YRE + ++ E+ L E + R + E +
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200
Query: 289 LQQYIER 295
++ ++R
Sbjct: 1201 EEEELQR 1207
Score = 42.4 bits (98), Expect = 0.002
Identities = 111/622 (17%), Positives = 234/622 (37%), Gaps = 58/622 (9%)
Query: 176 DMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEER 235
D + EEE P R RQ++ + E+ + + + R+R ++L ++ +E
Sbjct: 126 DRQLEEE----PGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRR-DEELWRQRQEW 180
Query: 236 KKMEKLLAGEDGTSERRKSIKTY--REIVQEKERRERELHEAYKNARSQ------EEAEG 287
++ E+ A E E+ +S K + E E++ R REL E + R + E +
Sbjct: 181 QEREERRAEE----EQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDR 236
Query: 288 ILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTA 347
+ Q+ E+ + R E K+ E + L + ++ L +Q L +
Sbjct: 237 VFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ---EEEEQLRKLERQELRRERQEE 293
Query: 348 TVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLK--------T 399
+ R + + + + + + + Q + +
Sbjct: 294 EQQQQRLRR---EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQ 350
Query: 400 FKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIE 459
+ + + + + RE+E+ER + L + Q ++ ++ E
Sbjct: 351 LRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 410
Query: 460 INIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTV 519
+++ + +E ++ +E++++ ++ + E + + R T
Sbjct: 411 QQLRREQQLRRE-----QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465
Query: 520 AFVEFPSSPQLKNDVSEEKDQK--KPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLD 577
+ QLK D EE+ ++ K E E + + Q++ + + E L
Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRL------ 519
Query: 578 KMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQE----RLL 633
K E + L S+ ++ K E+ RR+++ ++EQE +LL
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579
Query: 634 QERYQKEQDKLKEEWEK--AQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSS 691
+ ++ Q +LK E E+ Q+ EE R +EER+ E + QL S
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERR--EQRLKREEPEEERRQQLLKSE 637
Query: 692 SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAH 751
E + L Q E++++R K+ + + + LK RE + + L E
Sbjct: 638 EQEE----RRQQQLRREQQERREQRLKREEEEERLEQRLK-REHEEERREQELAEEEQEQ 692
Query: 752 SGNPVSKGVHE-DHQLDTEAGA 772
+ + + + QL++EA A
Sbjct: 693 ARERIKSRIPKWQWQLESEADA 714
Score = 42.4 bits (98), Expect = 0.002
Identities = 31/135 (22%), Positives = 62/135 (45%), Gaps = 16/135 (11%)
Query: 616 EEERRRQEKW----------QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEE 665
E E+RR+++W QQE+E+LL+E +K + + +E + ++E+++EE + E
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066
Query: 666 ERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDD 725
ER+ + Q + E + Q+ ++ R ++ Q ++
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR------QERERQCREEEELQQEE 1120
Query: 726 SDLLLKTRESDRLEE 740
LL + RE R +E
Sbjct: 1121 EQLLREEREKRRRQE 1135
Score = 42.0 bits (97), Expect = 0.003
Identities = 41/164 (25%), Positives = 73/164 (44%), Gaps = 19/164 (11%)
Query: 131 RKKKAEREEYRKSWSTATS-------PLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEA 183
R+ + +EE K W + L E P R + ++R E +
Sbjct: 233 RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQE 292
Query: 184 AVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDL----IKKEEERKKME 239
Q R R+EQ QL Q EE+ + Q + R + RR ++ +++E+E ++ +
Sbjct: 293 EEQQQQRLRREQ-QLRRKQ--EEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
Query: 240 KLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQE 283
+L ++ E R+ + RE QE+ERRE++L + R Q+
Sbjct: 350 QLRREQE---EERREQQLRRE--QEEERREQQLRREQQLRREQQ 388
Score = 40.8 bits (94), Expect = 0.006
Identities = 23/54 (42%), Positives = 37/54 (68%), Gaps = 4/54 (7%)
Query: 616 EEERRRQEKWQQEQERLLQERYQK--EQDKLKEEWEKAQKEVEEEERRYYEEER 667
EEE+ RQE Q++ R QERY+K E+++L+ E E+ Q +E +R++ EEE+
Sbjct: 1727 EEEQLRQETEQEQLRR--QERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Score = 40.4 bits (93), Expect = 0.007
Identities = 72/324 (22%), Positives = 134/324 (41%), Gaps = 46/324 (14%)
Query: 2 DSERQVKDTDDIESPKRSIRDSGYID---------CWDSERSDSLSPPR---HGRD-DSF 48
+ ERQ ++ ++++ KR R Y D W+ E+ +++ + GR+ + F
Sbjct: 1194 ERERQYREEEELQRQKRKQR---YRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQF 1250
Query: 49 DSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKS 108
L+ R RQ+ L G R + E R+ + + E K
Sbjct: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQERDREQE----RRRWQQRDRHFPEEEQLEREEQKE 1306
Query: 109 AVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGG--ERPFRYGPRTPVS 166
A + KS + + R++K R+E + + L E+P R R
Sbjct: 1307 A----KRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKF 1362
Query: 167 DDAESTSMFDMR--CEEEAAVQPHSRARQ---EQLQLI----NNQLREEDDKW----QDD 213
+ E R EEE ++ R R+ E+ QL QLR++ D+ +
Sbjct: 1363 REEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQ 1422
Query: 214 LARWKSRR--RSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERE 271
L+R + R R Q + ++E ERK +E+ + ER + + +++QE+E E++
Sbjct: 1423 LSRQERDRKFREEEQQVRRQERERKFLEE---EQQLRQERHRKFREEEQLLQERE--EQQ 1477
Query: 272 LHEAYKNARSQEEAEGILQQYIER 295
LH ++ + EE + + +Q +R
Sbjct: 1478 LHRQERDRKFLEEEQQLRRQERDR 1501
Score = 40.0 bits (92), Expect = 0.010
Identities = 56/252 (22%), Positives = 107/252 (42%), Gaps = 22/252 (8%)
Query: 80 ESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREE 139
E L + ++++++ RR E + + L + Q R+++ +
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQERQYRE--EEQLQQEEEQLLREEREKRRRQERERQ 959
Query: 140 YRKS--WSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQ 197
YRK L GE P + R + + +++ EEE ++ R+ Q
Sbjct: 960 YRKDKKLQQKEEQLLGEEPEK---RRRQEREKKYREEEELQQEEEQLLREEREKRRRQEW 1016
Query: 198 LINNQLREEDDKWQDD---LARWKSRRRSVSQDL-IKKEEERKKMEKLLAGEDGTSERRK 253
Q R++D+ Q++ L + +RR ++ ++EEE ++ E+ L GE+ + RR+
Sbjct: 1017 --ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQ 1074
Query: 254 SI-KTYREIVQEKERRERELHEAYKNARSQE-----EAEGILQQYIERFTISEAVLERLE 307
+ + YR+ + ++ E+ L E + R QE E LQQ E+ E R +
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ 1134
Query: 308 MPKILERSHSTE 319
LER + E
Sbjct: 1135 E---LERQYREE 1143
Score = 39.3 bits (90), Expect = 0.017
Identities = 31/148 (20%), Positives = 68/148 (45%), Gaps = 4/148 (2%)
Query: 616 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRY-YEEERKIIEDTV 674
EEE+ RQE+ +Q+ +R +E+++L++E E+ Q ++ + +Y +EEE+ +E+
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834
Query: 675 VPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRE 734
+ + E S + + Q+E+Q RR ++ + + + + +E
Sbjct: 1835 QRLRQERDRQYRAEEQFATQEKS---RREEQELWQEEEQKRRQERERKLREEHIRRQQKE 1891
Query: 735 SDRLEEKGSLTEGALAHSGNPVSKGVHE 762
R + G + G + G H+
Sbjct: 1892 EQRHRQVGEIKSQEGKGHGRLLEPGTHQ 1919
Score = 38.9 bits (89), Expect = 0.022
Identities = 18/51 (35%), Positives = 33/51 (64%)
Query: 616 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE 666
E + R +E+ QQE+E+LL+E +K + + E + ++EV++EE + EE
Sbjct: 1107 ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREE 1157
Score = 38.5 bits (88), Expect = 0.028
Identities = 127/646 (19%), Positives = 237/646 (36%), Gaps = 96/646 (14%)
Query: 180 EEEAAVQPHSRARQEQLQLINNQLRE----EDDKWQDDLARW-----KSRRRSVSQDLIK 230
EEE Q + +E+ + Q RE +D K Q + + RRR + +
Sbjct: 932 EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYR 991
Query: 231 KEEERKKMEKLLAGEDGTSERRKSI-KTYR---EIVQEKE---RRERELHEAYKNARSQE 283
+EEE ++ E+ L E+ RR+ + YR E+ QE+E R ERE + R
Sbjct: 992 EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYR 1051
Query: 284 EAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQ----QS 339
E E + Q+ + R E+ + + + L + P K RQ Q
Sbjct: 1052 EEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLRE-EPEKRRRQERERQC 1110
Query: 340 LPPPKFTATVETTIA------RASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNS 393
+ E + R L+ + V + +L +P + +
Sbjct: 1111 REEEELQQEEEQLLREEREKRRRQELERQYRE-----EEEVQQEEEQLLREEP--EKRRR 1163
Query: 394 QDVLKTFKVDGKVSVNGETVHREE------EKERECPTVAPAHSLTKSQMFEGVARVHGS 447
Q++ + ++ + ++ E + REE E+ER+ + Q + R
Sbjct: 1164 QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRY----RDEDQ 1219
Query: 448 PLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQH 507
+LK + N + N V E + ED + + +++ E Q
Sbjct: 1220 RSDLKWQWEPEKENAVRDNKV---YCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE 1276
Query: 508 FTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEP 567
R FP QL+ + E+K+ K+ + + + +L+ ++ K + E
Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLERE--EQKEAKRRDRKSQEEKQLLREEREEKRRRQET 1334
Query: 568 EATLTFPFLDKMPEANQL-----HLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQ 622
+ K E QL P + D E+ + E+ RRQ
Sbjct: 1335 DR--------KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQ 1386
Query: 623 EK------------WQQEQERLLQERYQK----EQDKLKEEWEKAQKEVE------EEER 660
E+ Q+ +++L Q+R +K EQ ++E ++ +E E E ER
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERER 1446
Query: 661 RYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKS 720
++ EEE+++ ++ F ++ E + D ++E+Q RR ++
Sbjct: 1447 KFLEEEQQLRQERHRKF------REEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD 1500
Query: 721 FQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQL 766
+ + +L + E LEE+ L H K + E+ QL
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQL------HRQQRQRKFLQEEQQL 1540
Score = 38.1 bits (87), Expect = 0.037
Identities = 21/66 (31%), Positives = 41/66 (62%), Gaps = 11/66 (16%)
Query: 616 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRY---------YEEE 666
E++ RRQE+ QQ ++ ++R +E+++L++E E+ Q +E +R++ E+E
Sbjct: 1537 EQQLRRQERGQQRRQD--RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594
Query: 667 RKIIED 672
RK +ED
Sbjct: 1595 RKFMED 1600
Score = 37.7 bits (86), Expect = 0.049
Identities = 21/59 (35%), Positives = 38/59 (64%), Gaps = 1/59 (1%)
Query: 614 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 672
+ E++ RRQE+ ++ + Q R Q+ + K +EE E+ ++E E+E+ R E RKI+E+
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREE-EQLRQETEQEQLRRQERYRKILEE 1752
Score = 37.4 bits (85), Expect = 0.063
Identities = 42/208 (20%), Positives = 83/208 (39%), Gaps = 17/208 (8%)
Query: 131 RKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSR 190
R++ EREE R S G E P + + ++R + Q R
Sbjct: 177 RQEWQEREERRAEEEQLQSCKGHETE-----EFPDEEQLRRRELLELRRKGREEKQQQRR 231
Query: 191 ARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSE 250
RQ+++ +EE++K W+ R + ++ K +EE + ++ L E+
Sbjct: 232 ERQDRV------FQEEEEK------EWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLR 279
Query: 251 RRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPK 310
+ + + RE +E+++++R E + +EE ++ E+ E ER E
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQL 339
Query: 311 ILERSHSTEPNLSSFLNDPNPMKYLRQQ 338
E+ E L + + LR++
Sbjct: 340 RREQEERREQQLRREQEEERREQQLRRE 367
Score = 37.0 bits (84), Expect = 0.083
Identities = 22/64 (34%), Positives = 41/64 (64%), Gaps = 7/64 (10%)
Query: 616 EEERRRQEKWQQ--EQERLLQERYQK-----EQDKLKEEWEKAQKEVEEEERRYYEEERK 668
+E+ RRQE++++ E+E+L ER ++ E+D+ E E+ ++E EE++ R E +RK
Sbjct: 1737 QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRK 1796
Query: 669 IIED 672
E+
Sbjct: 1797 FREE 1800
Score = 36.2 bits (82), Expect = 0.14
Identities = 29/117 (24%), Positives = 59/117 (50%), Gaps = 10/117 (8%)
Query: 176 DMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVS--QDLIKKEE 233
D + EE + +Q + Q + + REE+ + L R + R+ + Q L ++E
Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQ----LRRQERERKFLQEEQQLRRQEL 1721
Query: 234 ERKKMEKLLAGEDGTSERRKSIKTYREIVQEK----ERRERELHEAYKNARSQEEAE 286
ERK E+ ++ E+ + + YR+I++E+ ER E++L ++ + +EE +
Sbjct: 1722 ERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Score = 35.8 bits (81), Expect = 0.18
Identities = 18/56 (32%), Positives = 38/56 (67%), Gaps = 2/56 (3%)
Query: 614 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKI 669
+ E + RRQE+ ++Q R ++R +E+++L +E E+ Q +E +R++ EEE+++
Sbjct: 1647 EEEPQLRRQER--EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQL 1700
Score = 35.4 bits (80), Expect = 0.24
Identities = 31/152 (20%), Positives = 71/152 (46%), Gaps = 13/152 (8%)
Query: 133 KKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRAR 192
+K ER+E R+ ++ R + + E + R E++ + R
Sbjct: 279 RKLERQELRRERQEEEQQ---QQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR 335
Query: 193 QEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERR 252
++QL+ RE++++ + L R + R Q +++E+E ++ E+ L E R
Sbjct: 336 EQQLR------REQEERREQQLRREQEEERREQQ--LRREQEEERREQQLRREQ-QLRRE 386
Query: 253 KSIKTYREIVQEKE-RRERELHEAYKNARSQE 283
+ ++ +++ +E++ RRE++L + R Q+
Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Score = 35.4 bits (80), Expect = 0.24
Identities = 21/57 (36%), Positives = 36/57 (63%), Gaps = 4/57 (7%)
Query: 614 DPEEERRRQEKWQQ-EQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKI 669
+ E++ RRQE QQ QER +R +E ++L +E E+ Q +E +R++ EEE ++
Sbjct: 1599 EDEQQLRRQEGQQQLRQER---DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQL 1652
Score = 35.0 bits (79), Expect = 0.31
Identities = 18/57 (31%), Positives = 35/57 (61%)
Query: 616 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 672
E+ER+ E QQ + + Q++ ++E+D+ E E+ +E EE++ E +RK +E+
Sbjct: 1592 EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEE 1648
Score = 34.3 bits (77), Expect = 0.54
Identities = 34/126 (26%), Positives = 66/126 (52%), Gaps = 11/126 (8%)
Query: 180 EEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRR------RSVSQDLIKKEE 233
+EE ++ R +Q + Q + + REE+ Q+ + SR+ R Q + ++E+
Sbjct: 1535 QEEQQLRRQERGQQRR-QDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 234 ERKKM--EKLLAGEDGTSE-RRKSIKTYREIVQ-EKERRERELHEAYKNARSQEEAEGIL 289
ERK M E+ L ++G + R++ + +RE Q +ER E++LH ++ + EE +
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653
Query: 290 QQYIER 295
+Q E+
Sbjct: 1654 RQEREQ 1659
Score = 34.3 bits (77), Expect = 0.54
Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 13/123 (10%)
Query: 170 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDD---KWQDDLARWKSRRRSVSQ 226
E + R E++ Q R +E+ QL Q REE + +D RW+ + + +
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQL--RQEREEQQLRPQQRDGKYRWEEEQLQLEE 1832
Query: 227 DLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKER-----RERELHEAYKNARS 281
+ +ER + + E+ + + KS + +E+ QE+E+ RER+L E + +
Sbjct: 1833 QEQRLRQERDRQYR---AEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQ 1889
Query: 282 QEE 284
+EE
Sbjct: 1890 KEE 1892
Score = 34.3 bits (77), Expect = 0.54
Identities = 20/64 (31%), Positives = 39/64 (60%), Gaps = 12/64 (18%)
Query: 614 DPEEERRRQEK---WQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKII 670
+ +E+R RQE+ ++ E++ QE+ ++E+ +L W+ EEE++R E ERK+
Sbjct: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRREEQEL---WQ------EEEQKRRQERERKLR 1881
Query: 671 EDTV 674
E+ +
Sbjct: 1882 EEHI 1885
Score = 34.3 bits (77), Expect = 0.54
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 4/54 (7%)
Query: 611 WAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYE 664
+A + R QE WQ+E+ Q+R Q+ + KL+EE + Q++ E+ R+ E
Sbjct: 1851 FATQEKSRREEQELWQEEE----QKRRQERERKLREEHIRRQQKEEQRHRQVGE 1900
Score = 33.9 bits (76), Expect = 0.70
Identities = 29/125 (23%), Positives = 60/125 (48%), Gaps = 5/125 (4%)
Query: 192 RQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSER 251
++ + Q ++ Q R+ ++ R + R + + D +K E +++ L GE+ R
Sbjct: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQL--LQEGEEQQLRR 1686
Query: 252 RKSIKTYREIVQEKERRERE---LHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEM 308
++ + +RE Q+ R+ERE L E + R + E + ++ + + T E + +
Sbjct: 1687 QERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERY 1746
Query: 309 PKILE 313
KILE
Sbjct: 1747 RKILE 1751
Score = 33.5 bits (75), Expect = 0.92
Identities = 20/62 (32%), Positives = 38/62 (61%), Gaps = 11/62 (17%)
Query: 619 RRRQEKW-QQEQERLLQERYQ----------KEQDKLKEEWEKAQKEVEEEERRYYEEER 667
++RQ K+ Q+EQ+ QER Q +E+++L++E E+ Q +E +R++ EE+
Sbjct: 1527 QQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQ 1586
Query: 668 KI 669
K+
Sbjct: 1587 KV 1588
Score = 33.5 bits (75), Expect = 0.92
Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 8/62 (12%)
Query: 616 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQ--------KEVEEEERRYYEEER 667
EEE+ R E+ +Q+ R ++R +E+++L++E E+ Q K EEE+ R EE+
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ 1810
Query: 668 KI 669
++
Sbjct: 1811 QL 1812
Score = 33.1 bits (74), Expect = 1.2
Identities = 28/114 (24%), Positives = 53/114 (46%), Gaps = 6/114 (5%)
Query: 181 EEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEK 240
EE + R R+ +L+ + +E++ K+ +D + RR Q +++E +RK E
Sbjct: 1568 EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDE---QQLRRQEGQQQLRQERDRKFRED 1624
Query: 241 ---LLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ 291
L E+ R++ + + E + R+ERE + R E E +LQ+
Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE 1678
Score = 32.7 bits (73), Expect = 1.6
Identities = 36/155 (23%), Positives = 66/155 (42%), Gaps = 7/155 (4%)
Query: 131 RKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSR 190
R+++ RE+ + ER + R + E + + E ++ +
Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQ 394
Query: 191 ARQEQLQLINNQLREEDD-KWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTS 249
R+EQ QLR E + + L R + RR ++ +++ E+++ E+ L E
Sbjct: 395 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ--E 452
Query: 250 ERRKSIKTYREIVQEKERRERELHEAYKNARSQEE 284
ERR +K RE +E ER E+E + +EE
Sbjct: 453 ERRDWLK--RE--EETERHEQERRKQQLKRDQEEE 483
Score = 32.7 bits (73), Expect = 1.6
Identities = 32/145 (22%), Positives = 65/145 (44%), Gaps = 14/145 (9%)
Query: 180 EEEAAVQPHSRARQEQLQLINNQ------LREEDDKWQDD---LARWKSRRRSVSQDLIK 230
EE+ Q R +E+ QL+ + +E D K+ ++ L R + R+ Q+L
Sbjct: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS 1510
Query: 231 KEEERKKMEKLLAGEDGTSERR-----KSIKTYREIVQEKERRERELHEAYKNARSQEEA 285
+E ERK +E+ +R+ + ++ Q ++ R+R+ E + + +EE
Sbjct: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQ 1570
Query: 286 EGILQQYIERFTISEAVLERLEMPK 310
+ Q+ +F + E + R E +
Sbjct: 1571 QLSRQERDRKFRLEEQKVRRQEQER 1595
Score = 32.0 bits (71), Expect = 2.7
Identities = 16/54 (29%), Positives = 36/54 (66%), Gaps = 1/54 (1%)
Query: 616 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKI 669
+ +R+ +E+ Q QER Q+ ++E+D+ K E+ + +E+ER++ E+E+++
Sbjct: 1552 DRDRKFREEEQLRQEREEQQLSRQERDR-KFRLEEQKVRRQEQERKFMEDEQQL 1604
Score = 32.0 bits (71), Expect = 2.7
Identities = 44/189 (23%), Positives = 74/189 (39%), Gaps = 23/189 (12%)
Query: 616 EEERRRQEKWQQEQERLLQERYQK----EQDKLKEEWEKAQKEVEEEERRY-------YE 664
EEE+ RQE+ +Q+ R QER +K EQ ++E E+ E E++ RR E
Sbjct: 1559 EEEQLRQEREEQQLSR--QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQE 1616
Query: 665 EERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQ-- 722
+RK ED + + E + + + +DR++++ Q
Sbjct: 1617 RDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLL 1676
Query: 723 --GDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQ 780
G++ L + R+ EE+ L K + E+ QL + Q
Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERER------KFLQEEQQLRRQELERKFREEEQ 1730
Query: 781 LAQDPSQNQ 789
L Q+ Q Q
Sbjct: 1731 LRQETEQEQ 1739
Score = 30.8 bits (68), Expect = 5.9
Identities = 21/56 (37%), Positives = 38/56 (67%), Gaps = 6/56 (10%)
Query: 616 EEERRRQEKWQQ--EQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKI 669
E++ RRQE ++ E+E+L QE EQ++L+ + E+ +K +EEE+ R EE+++
Sbjct: 1713 EQQLRRQELERKFREEEQLRQET---EQEQLRRQ-ERYRKILEEEQLRPEREEQQL 1764
Score = 30.4 bits (67), Expect = 7.8
Identities = 43/165 (26%), Positives = 72/165 (43%), Gaps = 32/165 (19%)
Query: 176 DMRCEEEAAV--QPHSRARQEQLQLINNQLREEDDKWQDD--LARWKSRRRSVSQDLIKK 231
+++ EEE + + +R RQE + Q R+E++ Q++ L R + +R ++
Sbjct: 1055 ELQQEEEQLLGEERETRRRQE----LERQYRKEEELQQEEEQLLREEPEKRR------RQ 1104
Query: 232 EEER---------KKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQ 282
E ER ++ E+LL E R++ + YRE + ++ E+ L E + R Q
Sbjct: 1105 ERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQ 1164
Query: 283 E-----EAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNL 322
E E LQQ E+ E R E ER + E L
Sbjct: 1165 ELERQYREEEELQQEEEQLLREEQEKRRQER----ERQYREEEEL 1205
>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
Length = 564
Score = 48.5 bits (114), Expect = 3e-05
Identities = 124/612 (20%), Positives = 230/612 (37%), Gaps = 93/612 (15%)
Query: 212 DDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERE 271
DD R + RR K+EE R + E++ + E + + R QE+ R+++E
Sbjct: 2 DDFERRRELRRQ------KREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQE 55
Query: 272 LHEAYKNARSQEE--AEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDP 329
E+ Q E A+ + + T + +E + LER E L +
Sbjct: 56 -EESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQE- 113
Query: 330 NPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQ 389
RQ+ P TI AS+ S + + T K + + +
Sbjct: 114 ---ALERQKEFDP---------TITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYE 161
Query: 390 PKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPL 449
+ ++ V K+++ + E ++EKE E S+ ++Q E +V
Sbjct: 162 IEETETVTKSYQKNDWRDAE-ENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKRE 220
Query: 450 ELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFT 509
+L++D KP +E+ K + +E+ +KG E+ S + T
Sbjct: 221 KLQED---------KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMT 271
Query: 510 TTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVL-------SQKVVKP 562
+ T S P + V ++ + P+ E ++E + S++ K
Sbjct: 272 HKLKHTENTF------SRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKL 325
Query: 563 KSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQ 622
K + EA L L K E E+ V+ + EE+RR+Q
Sbjct: 326 KQKQQEAALELEELKKKRE------------------ERRKVL--------EEEEQRRKQ 359
Query: 623 EKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSS 682
E E +R L+E ++E+ +LKEE E+ + E E+ ++ E+ + FT S
Sbjct: 360 E----EADRKLRE--EEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGS 413
Query: 683 S------ADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 736
S A+ L+ S + G + ++ + + D + + ++ + +G S K SD
Sbjct: 414 SLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLE-QYTSAIEGTKSAKPTKPAASD 472
Query: 737 -RLEEKGSLTEGALAHSGN----PVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQT 791
+ +G ++ GN P + G + G N L + P N+
Sbjct: 473 LPVPAEGVRNIKSMWEKGNVFSSPTAAGTPNKETAGLKVGV-SSRINEWLTKTPDGNK-- 529
Query: 792 SNPTHSSEDVKP 803
+P D++P
Sbjct: 530 -SPAPKPSDLRP 540
Score = 40.4 bits (93), Expect = 0.007
Identities = 50/262 (19%), Positives = 101/262 (38%), Gaps = 45/262 (17%)
Query: 614 DPEEERRRQEKWQQEQERLLQER--YQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIE 671
D E RR + ++E+ RL ER YQ+ D +E + ++ +E R +EE + +
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 672 DT-VVPFTVSSSSADQ---LSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGD--- 724
T V +S D+ +T+++ EG ++ ++E++ +R +++ +
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEF 121
Query: 725 -----DSDLLLKTR----------------------ESDRLEEKGSLTEGALAHSGNPVS 757
D+ L L +R E +EE ++T+ +
Sbjct: 122 DPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAE 181
Query: 758 KGVHEDHQLDTEA---------GAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTLPL 808
+ ED + + E G Q + Q PT E++K + +
Sbjct: 182 ENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKK 241
Query: 809 DKSINHQIESPSERRKSISGKK 830
DK +++S +R+K + K
Sbjct: 242 DKEPKEEVKSFMDRKKGFTEVK 263
Score = 37.0 bits (84), Expect = 0.083
Identities = 51/243 (20%), Positives = 89/243 (36%), Gaps = 27/243 (11%)
Query: 585 LHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKL 644
L LP+ Q D+ +E + E+ RQE+++ E+ + + YQK +
Sbjct: 130 LSLPSRRMQNDTAENETTE----------KEEKSESRQERYEIEETETVTKSYQKNDWRD 179
Query: 645 KEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKID 704
EE +K KE EE EEE K ++ + + E T K +
Sbjct: 180 AEENKKEDKEKEE------EEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEE 233
Query: 705 LGN--CQDEKQDRRWKKSFQGDDSDLL-LKTRESDRLEEKGSLTEGALAHSGNPVSKGVH 761
+ + + +K+ + KSF +K++ + + K TE + G S
Sbjct: 234 IKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTK 293
Query: 762 EDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSE 821
E GAP +L + + +T + E +K K + + E
Sbjct: 294 E------AEGAPQVEAGKRLEELRRRRGETE--SEEFEKLKQKQQEAALELEELKKKREE 345
Query: 822 RRK 824
RRK
Sbjct: 346 RRK 348
Score = 34.3 bits (77), Expect = 0.54
Identities = 38/170 (22%), Positives = 72/170 (42%), Gaps = 14/170 (8%)
Query: 128 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPR-TPVSDDAESTSMFDMRCEEEAAVQ 186
A ++ A REE R+ ER + P T S S M + E E +
Sbjct: 94 AAFLERLARREERRQKRLQEAL----ERQKEFDPTITDASLSLPSRRMQNDTAENETTEK 149
Query: 187 PH-SRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGE 245
S +RQE+ ++ + + + D W+ + +D K+EEE +K ++ GE
Sbjct: 150 EEKSESRQERYEIEETETVTKSYQKND----WRDAEENKKEDKEKEEEEEEKPKRGSIGE 205
Query: 246 DGTSERRKSIKTYREIVQEK----ERRERELHEAYKNARSQEEAEGILQQ 291
+ E+ ++ RE +QE ++ E + + K+ +EE + + +
Sbjct: 206 NQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDR 255
Score = 33.1 bits (74), Expect = 1.2
Identities = 23/107 (21%), Positives = 55/107 (51%), Gaps = 9/107 (8%)
Query: 180 EEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKME 239
E E A Q + R E+L+ R + ++ + K +++ + +L + +++R++
Sbjct: 294 EAEGAPQVEAGKRLEELR------RRRGETESEEFEKLKQKQQEAALELEELKKKREERR 347
Query: 240 KLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAE 286
K+L E+ +RRK + R++ +E+E+R + + A + E+ +
Sbjct: 348 KVLEEEE---QRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQ 391
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 48.1 bits (113), Expect = 4e-05
Identities = 31/134 (23%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Query: 534 VSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQ 593
+ E++++++ + E K E + ++ K + E + + + E Q + Q
Sbjct: 593 IREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652
Query: 594 VDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQK 653
+ E+ M + W EE+ R QEK +EQE ++E+ + Q++ ++ WE+ +K
Sbjct: 653 -EEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 711
Query: 654 EVEEEERRYYEEER 667
E+EE+ +EE+
Sbjct: 712 MCEQEEKMQEQEEK 725
Score = 47.0 bits (110), Expect = 8e-05
Identities = 36/148 (24%), Positives = 77/148 (52%), Gaps = 5/148 (3%)
Query: 176 DMRCEEEAAVQPHSRARQE-QLQLINNQLREEDDKWQDDLAR-WKSRRRSVSQDLIKKEE 233
+ R EEE + R QE ++ ++RE+++K ++ + W+ + Q+ I++EE
Sbjct: 411 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 470
Query: 234 ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAY--KNARSQEEAEGILQQ 291
+R++ E++ E+ E ++ I +E + E+E + R+ E + + +E+ E I +Q
Sbjct: 471 KRQEQEEMWRQEEKIHE-QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ 529
Query: 292 YIERFTISEAVLERLEMPKILERSHSTE 319
+ + E + E+ EM + E+ H E
Sbjct: 530 EEKMWRQEEKIREQEEMWREEEKMHEQE 557
Score = 46.2 bits (108), Expect = 1e-04
Identities = 26/72 (36%), Positives = 44/72 (61%), Gaps = 4/72 (5%)
Query: 600 EKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQK--EQDKLKEEWEKAQKE--V 655
EK M + W+ EE+ RRQE+ E+E ++E +K EQ+K++E+ EK Q+E +
Sbjct: 360 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 419
Query: 656 EEEERRYYEEER 667
E+E+R +E +
Sbjct: 420 REQEKRQEQEAK 431
Score = 42.4 bits (98), Expect = 0.002
Identities = 30/135 (22%), Positives = 61/135 (45%), Gaps = 9/135 (6%)
Query: 613 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQK------EVEEEERRYYEEE 666
W EE+ R QE+ QE ++E+ +K Q++ ++ W++ +K +++E+E + E+E
Sbjct: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632
Query: 667 RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS 726
KI E + +Q M E M + + + E++ R +K + +
Sbjct: 633 EKIREQEEMTQEQEEKMGEQ---EEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEE 689
Query: 727 DLLLKTRESDRLEEK 741
+ + EEK
Sbjct: 690 KIREQEEMMQEQEEK 704
Score = 42.0 bits (97), Expect = 0.003
Identities = 18/60 (30%), Positives = 39/60 (65%), Gaps = 5/60 (8%)
Query: 613 WDPEEERRRQEK-WQQEQERLLQERYQKEQDKLKEE----WEKAQKEVEEEERRYYEEER 667
W EE+ QEK W++E+ + +++ ++++K++E+ W + +K E+EE+R +EE+
Sbjct: 547 WREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
Score = 41.6 bits (96), Expect = 0.003
Identities = 28/141 (19%), Positives = 70/141 (49%), Gaps = 7/141 (4%)
Query: 613 WDPEEERRRQEK-WQQEQE-RLLQERYQKEQDKLKEEWEKAQKEVE---EEERRYYEEER 667
W+ E+ + +++K W+QE++ R +E+ ++++K++E+ EK Q++ E ++E + E+E
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 619
Query: 668 KIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNK--IDLGNCQDEKQDRRWKKSFQGDD 725
KI E +Q + E G + + E+++ W++ + +
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE 679
Query: 726 SDLLLKTRESDRLEEKGSLTE 746
+ ++ +E E++ + E
Sbjct: 680 QEKKIREQEEKIREQEEMMQE 700
Score = 41.2 bits (95), Expect = 0.004
Identities = 32/118 (27%), Positives = 63/118 (53%), Gaps = 12/118 (10%)
Query: 180 EEEAAVQPHSRARQEQLQLINNQLREEDDK-W-QDDLARWKSRRRSVSQDLIKKEEE--R 235
EE+ Q RQE+ ++RE+++K W Q++ R + +R ++ + K+EE R
Sbjct: 562 EEKRQEQEDKMWRQEE------KIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR 615
Query: 236 KKMEKLLAGEDGTSERRKSIKTYREIVQEKERR--ERELHEAYKNARSQEEAEGILQQ 291
++ EK+ E+ E+ + I+ E+ QE+E + E+E + + QE+ E + +Q
Sbjct: 616 EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673
Score = 40.4 bits (93), Expect = 0.007
Identities = 22/61 (36%), Positives = 39/61 (63%), Gaps = 7/61 (11%)
Query: 613 WDPEEERRRQEK--WQQEQERLLQER--YQKEQDKLKEE---WEKAQKEVEEEERRYYEE 665
W+ EE+ RRQE+ W++E++ QE ++KE+ ++E WEK +K E EE+ + +E
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 404
Query: 666 E 666
+
Sbjct: 405 K 405
Score = 40.0 bits (92), Expect = 0.010
Identities = 40/160 (25%), Positives = 76/160 (47%), Gaps = 29/160 (18%)
Query: 531 KNDVSEEKDQKKPENEMSGKVELVLSQK------VVKPKSPEPEATLTFPFLDKMPEANQ 584
+N +++E + K+ ++ K++LV S+K V + K A L P EA+
Sbjct: 211 RNTITDE-ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD- 268
Query: 585 LHLPNLNSQVDSPSSEKSPVMTPFKFWA---WDPEEERRRQEKWQQEQERLLQERYQK-- 639
+L ++ S S++ + + W EE+ RQE+ QE E +QE+ +K
Sbjct: 269 ----HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324
Query: 640 -EQDKLKEE-----------WEKAQKEVEEEERRYYEEER 667
+++K++E+ WEK +K +EE + +EE+
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364
Score = 40.0 bits (92), Expect = 0.010
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 10/121 (8%)
Query: 180 EEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEE----- 234
EE+ Q RQE+ ++REE+ K Q+ W+ + Q+ I +++E
Sbjct: 443 EEKIREQEKKMWRQEEKIHEQEKIREEE-KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ 501
Query: 235 ----RKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQ 290
RK+ EK+ E+ E+ + I+ E + +E + RE E ++ E E I +
Sbjct: 502 EEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE 561
Query: 291 Q 291
+
Sbjct: 562 E 562
Score = 40.0 bits (92), Expect = 0.010
Identities = 19/58 (32%), Positives = 36/58 (62%), Gaps = 3/58 (5%)
Query: 613 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEE---WEKAQKEVEEEERRYYEEER 667
W EE+ QEK ++E++R QE ++++K+ E+ W + +K E+EE+ +EE+
Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEK 511
Score = 40.0 bits (92), Expect = 0.010
Identities = 22/61 (36%), Positives = 40/61 (65%), Gaps = 5/61 (8%)
Query: 616 EEERRR--QEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEE---EERRYYEEERKII 670
EEE+R+ +E W+QE++ QE ++++K+ E+ EK +K+ E+ +E + E+E KI
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
Query: 671 E 671
E
Sbjct: 528 E 528
Score = 40.0 bits (92), Expect = 0.010
Identities = 25/120 (20%), Positives = 59/120 (49%), Gaps = 2/120 (1%)
Query: 190 RARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKME-KLLAGEDGT 248
R ++E+++ ++ +++K ++ W+ + Q+ I +EE+R++ E K+ E+
Sbjct: 520 REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKI 579
Query: 249 SERRKSIKTYREIVQEKERRERELHE-AYKNARSQEEAEGILQQYIERFTISEAVLERLE 307
E+ + + E ++E+E + +E E +K E E +Q+ E+ E + E
Sbjct: 580 REQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQE 639
Score = 40.0 bits (92), Expect = 0.010
Identities = 28/121 (23%), Positives = 60/121 (49%), Gaps = 7/121 (5%)
Query: 178 RCEEEAAVQPHSRARQEQ-LQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERK 236
R EE+ Q R QE+ + ++RE+++K Q+ + + + + + +E+ +
Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE 647
Query: 237 KM----EKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS--QEEAEGILQ 290
KM EK+ E+ E+ +++ E ++E+E++ RE E + QE+ E + +
Sbjct: 648 KMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 707
Query: 291 Q 291
Q
Sbjct: 708 Q 708
Score = 38.9 bits (89), Expect = 0.022
Identities = 26/118 (22%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Query: 180 EEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEER---- 235
EE+ Q RQE+ ++ E++K + W+ +R +D + ++EE+
Sbjct: 523 EEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ 582
Query: 236 -----KKMEKLLAGEDGTSERRKSIKTYREIVQEKERR----ERELHEAYKNARSQEE 284
++ EK+ E+ E+ + + E ++E+E + E ++ E + R QEE
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEE 640
Score = 38.5 bits (88), Expect = 0.028
Identities = 37/156 (23%), Positives = 77/156 (49%), Gaps = 16/156 (10%)
Query: 180 EEEAAVQPHSRARQEQLQLINNQLREEDDK-WQDD--LARWKSRRRSVSQDLIKKEEE-R 235
+E +V +A+ E+ +L N +++++K W+ + + W+ + + + + ++EE+ R
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331
Query: 236 KKMEKLLAGEDGTSERRKSIKTYREIVQEKE----RRERELHEAYKNARSQEEAEGILQQ 291
++ EK+ E+ E+ + ++ E++ EKE R+E + E + R QEE ++
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 391
Query: 292 YI--------ERFTISEAVLERLEMPKILERSHSTE 319
I E+ I E +R E KI E+ E
Sbjct: 392 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 427
Score = 38.5 bits (88), Expect = 0.028
Identities = 32/160 (20%), Positives = 75/160 (46%), Gaps = 19/160 (11%)
Query: 177 MRCEEEAAVQPHSRARQEQLQLINNQ---LREEDDKWQDDLARWKSRRRSVSQDLIKKEE 233
MR +EE + + R+++ + + R+E+ W+ + + + Q+ I+++E
Sbjct: 351 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 410
Query: 234 ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE-----------RRERELHEAYKNARSQ 282
E+++ E+ + ++ E+ + E ++E+E R+E ++HE K R +
Sbjct: 411 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK-IREE 469
Query: 283 EEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNL 322
E+ Q+ E + E + E+ E+ + E+ H E +
Sbjct: 470 EKR----QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505
Score = 38.5 bits (88), Expect = 0.028
Identities = 18/62 (29%), Positives = 39/62 (62%), Gaps = 3/62 (4%)
Query: 613 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEK---AQKEVEEEERRYYEEERKI 669
W EE+ R QE+ +E+E++ ++ E++K +E+ +K ++++ E+E + + +E KI
Sbjct: 534 WRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKI 593
Query: 670 IE 671
E
Sbjct: 594 RE 595
Score = 38.5 bits (88), Expect = 0.028
Identities = 20/64 (31%), Positives = 41/64 (64%), Gaps = 6/64 (9%)
Query: 614 DPEEERRRQEKWQQEQERLL---QERYQKEQDKLKEEWEKAQKEVE---EEERRYYEEER 667
+ EE+ QE+ QEQE + +E+ ++++ K++E+ EK +++ E E+E + +E+E
Sbjct: 651 EQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 710
Query: 668 KIIE 671
K+ E
Sbjct: 711 KMCE 714
Score = 38.5 bits (88), Expect = 0.028
Identities = 22/64 (34%), Positives = 41/64 (64%), Gaps = 6/64 (9%)
Query: 614 DPEEERRRQEKWQQEQERLLQERYQK---EQDKLKEEWEKAQKEVE---EEERRYYEEER 667
+ EE+ R QE+ QEQE + E+ +K +++K++E+ EK +++ E E+E R ++E
Sbjct: 686 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745
Query: 668 KIIE 671
K+ E
Sbjct: 746 KMQE 749
Score = 38.1 bits (87), Expect = 0.037
Identities = 30/142 (21%), Positives = 71/142 (50%), Gaps = 8/142 (5%)
Query: 536 EEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQL--HLPNLNSQ 593
+E+ ++ E +M + E + Q+ ++ + E + +K+ E ++ ++ Q
Sbjct: 442 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ 501
Query: 594 VDSPSSEKSPVMTPFKFWAWDPEEERRRQEK-WQQEQERLLQERYQKEQDKLKEE---WE 649
+ ++ V + E+ R ++EK W+QE++ QE +E++K+ E+ WE
Sbjct: 502 EEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE 561
Query: 650 KAQKEVEEEERRYYEEERKIIE 671
+ ++ +E+E + + +E KI E
Sbjct: 562 EEKR--QEQEDKMWRQEEKIRE 581
Score = 37.7 bits (86), Expect = 0.049
Identities = 22/65 (33%), Positives = 41/65 (63%), Gaps = 9/65 (13%)
Query: 614 DPEEERRRQEK--WQQ-----EQERLLQERYQKEQDKLKEEWEK--AQKEVEEEERRYYE 664
+ EE+ R QEK W+Q EQE++ +E ++EQ+++ + EK Q+E+ ++ + +E
Sbjct: 441 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHE 500
Query: 665 EERKI 669
+E KI
Sbjct: 501 QEEKI 505
Score = 37.4 bits (85), Expect = 0.063
Identities = 21/61 (34%), Positives = 38/61 (62%), Gaps = 7/61 (11%)
Query: 614 DPEEERRRQEK--WQQEQERLLQER--YQKEQDKLKEE---WEKAQKEVEEEERRYYEEE 666
+ EE+ RRQE+ W++E++ QE ++KE+ ++E WEK +K +EE + +EE
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 391
Query: 667 R 667
+
Sbjct: 392 K 392
Score = 37.0 bits (84), Expect = 0.083
Identities = 17/54 (31%), Positives = 33/54 (61%)
Query: 614 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER 667
+ EE+ R QE+ + QE ++ E+ +K + + + WEK +K +EE + +EE+
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 378
Score = 37.0 bits (84), Expect = 0.083
Identities = 18/58 (31%), Positives = 37/58 (63%), Gaps = 5/58 (8%)
Query: 616 EEERRRQEKWQQEQERLLQERYQKEQDKLKEE----WEKAQKEVEEEERRYYEEERKI 669
EE+ QEK ++++E+ +E +EQ+K +E+ W + +K + E+E + E+E+K+
Sbjct: 397 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK-IREQEEKIREQEKKM 453
Score = 37.0 bits (84), Expect = 0.083
Identities = 18/61 (29%), Positives = 40/61 (65%), Gaps = 3/61 (4%)
Query: 614 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEK---AQKEVEEEERRYYEEERKII 670
+ E+ R ++EK Q+E++ QE+ Q+++ K+ + EK ++++ E+E++ + +E KI
Sbjct: 402 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 461
Query: 671 E 671
E
Sbjct: 462 E 462
Score = 37.0 bits (84), Expect = 0.083
Identities = 20/57 (35%), Positives = 38/57 (66%), Gaps = 3/57 (5%)
Query: 613 WDPEEERRRQEKWQQEQERLLQERYQK--EQDKLKEEWEK-AQKEVEEEERRYYEEE 666
W EE+ R QE+ +EQE+ + + +K EQ+K++EE ++ Q+E+ +E + +E+E
Sbjct: 433 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE 489
Score = 36.2 bits (82), Expect = 0.14
Identities = 27/121 (22%), Positives = 58/121 (47%), Gaps = 9/121 (7%)
Query: 180 EEEAAVQPHSRARQEQLQLINNQ---LREEDDKWQDDLARWKSRRRSVSQDLIKKEEERK 236
++E ++ QEQ + I Q +RE+++ Q+ + + + + K +E+ +
Sbjct: 609 KQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 668
Query: 237 KM----EKLLAGEDGTSERRKSIKTYREIVQEKERR--ERELHEAYKNARSQEEAEGILQ 290
M EK+ E E+ + I+ E++QE+E + E+E + + QE+ E + +
Sbjct: 669 TMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 728
Query: 291 Q 291
Q
Sbjct: 729 Q 729
Score = 35.8 bits (81), Expect = 0.18
Identities = 19/63 (30%), Positives = 41/63 (65%), Gaps = 12/63 (19%)
Query: 616 EEERRRQEKWQQEQERLL---QERYQKEQDKLKEE----WEKAQK-----EVEEEERRYY 663
EEE+ R+++ +QEQE + +E+ +++++K++E+ W + +K ++ EEE+R
Sbjct: 415 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 474
Query: 664 EEE 666
+EE
Sbjct: 475 QEE 477
Score = 35.0 bits (79), Expect = 0.31
Identities = 27/114 (23%), Positives = 52/114 (45%), Gaps = 6/114 (5%)
Query: 177 MRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERK 236
+R +EE + QE++ + +ED W+ + + + Q+ +E+E K
Sbjct: 540 IREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEK 599
Query: 237 KM---EKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEG 287
+ EK+ E+ E+ + I+ E ++E+E + RE E + QEE G
Sbjct: 600 RQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEM---TQEQEEKMG 650
Score = 32.3 bits (72), Expect = 2.0
Identities = 23/109 (21%), Positives = 54/109 (49%), Gaps = 6/109 (5%)
Query: 180 EEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI--KKEEERKK 237
EE+ Q RQE++ +EE + Q+++ K + ++++ K+E+ R++
Sbjct: 327 EEKIREQEEKMRRQEEMMWE----KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 382
Query: 238 MEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAE 286
E + E+ E + + +I +++E+R+ E + R ++EA+
Sbjct: 383 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 431
Score = 32.3 bits (72), Expect = 2.0
Identities = 17/61 (27%), Positives = 37/61 (60%), Gaps = 3/61 (4%)
Query: 614 DPEEERRRQEKWQQEQERLLQERYQK---EQDKLKEEWEKAQKEVEEEERRYYEEERKII 670
+ E + RQE+ +EQE ++E+ +K +++K+ E+ + ++E +E+ + +E KI
Sbjct: 427 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH 486
Query: 671 E 671
E
Sbjct: 487 E 487
Score = 31.2 bits (69), Expect = 4.5
Identities = 22/101 (21%), Positives = 50/101 (49%), Gaps = 17/101 (16%)
Query: 179 CEEEAAVQPHSRARQEQLQLINNQ---LREEDDKWQDDLARWKSRRRSVSQDLIKKEEER 235
CE+E +Q Q + I Q +RE+++K ++ +++++++EE+
Sbjct: 657 CEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ------------EEMMQEQEEK 704
Query: 236 --KKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHE 274
++ EK+ E+ E+ + ++ E + E+E R R+ E
Sbjct: 705 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745
Score = 30.8 bits (68), Expect = 5.9
Identities = 25/128 (19%), Positives = 62/128 (48%), Gaps = 16/128 (12%)
Query: 180 EEEAAVQPHSRARQEQLQLINNQLREEDDKW--------QDDLARWKSRRRSVSQDLIKK 231
E+E + R QE++ ++ E+++ W Q++ R + + ++ I++
Sbjct: 462 EQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIRE 521
Query: 232 EEE--RKKMEKLLAGEDGTSERRK------SIKTYREIVQEKERRERELHEAYKNARSQE 283
+EE R++ EK+ E+ E+ + + +I +E++R+E+E + + +E
Sbjct: 522 QEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIRE 581
Query: 284 EAEGILQQ 291
+ E + +Q
Sbjct: 582 QEEKVWRQ 589
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 47.8 bits (112), Expect = 5e-05
Identities = 86/404 (21%), Positives = 158/404 (39%), Gaps = 72/404 (17%)
Query: 385 KPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARV 444
K + ++ L + VS+ E EEKE E + KS V
Sbjct: 85 KVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSP-------V 137
Query: 445 HGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSE 504
+ E+K++ G E + ++ A +++ E +GG ++G+ E E
Sbjct: 138 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE--------EGGSEKEGSSEKEEGE 189
Query: 505 PQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPEN---EMSGKVELVLSQKVVK 561
+ E + + + + +E K++KK E E++ K ELV KV K
Sbjct: 190 QE----------------EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 233
Query: 562 P---KSPEPEATLTFPF---LDKMPEANQLHLPNLNSQVD---------SPSSE--KSPV 604
P KSP P++ + + K P + P S V+ SP E KSPV
Sbjct: 234 PEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 293
Query: 605 -MTPFKFWAWDP------EEERRRQE--KWQQEQERLLQERYQKEQDKLKEEWEKAQKEV 655
+P + A P EE + + E K +Q++E + + +++K++++ EK +
Sbjct: 294 SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVP 353
Query: 656 EEEERRYYEEERKIIEDTVVPFTV-------SSSSADQLSTSSSMTEGSGTMNKIDLGNC 708
E+++ +E + E + +V + L + G + G+
Sbjct: 354 EKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSD 413
Query: 709 QDEKQDRRWKKSFQG-----DDSDLLLKTRESDRLEEKGSLTEG 747
+ K R+ + G ++ + K + S R EEKG +T G
Sbjct: 414 KGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNG 457
Score = 45.8 bits (107), Expect = 2e-04
Identities = 78/362 (21%), Positives = 150/362 (41%), Gaps = 42/362 (11%)
Query: 165 VSDDAESTSMFDMRCEEEAAVQPHSR----ARQEQLQLINNQLREEDDKWQDDLARWKSR 220
V + E T + D + E E A+ + + +E+ + + EE + ++++A KS
Sbjct: 77 VEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSP 136
Query: 221 RRS----VSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAY 276
++ V ++ +KEEE + E+ E S++ + + +E EKE E+E E
Sbjct: 137 VKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE 196
Query: 277 KNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTE-PNLSSFLND------- 328
A EEAE ++ +E + A E L +E+ + P S + +
Sbjct: 197 AEAEG-EEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP 255
Query: 329 PNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYS 388
+P++ + +P ++ + ++ V + S S SP V KA + P
Sbjct: 256 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSP---VEEKAKSPVPKSPVE 312
Query: 389 QPKNSQDVLK-----TFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVAR 443
+ K+ +V K + + K + E V ++EEK ++ P A S K + V
Sbjct: 313 EAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVT 372
Query: 444 VHGSPLELKQDNGSIEINIKKPNS-----VPQELAATTEKTEPNSQEDKNDGGK--SRKG 496
+ S++++++K + QE E S+E+ +D G SRK
Sbjct: 373 I----------TKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKE 422
Query: 497 NI 498
+I
Sbjct: 423 DI 424
Score = 34.3 bits (77), Expect = 0.54
Identities = 50/227 (22%), Positives = 91/227 (40%), Gaps = 44/227 (19%)
Query: 546 EMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLP--NLNSQVDSPSSEKSP 603
+M+ +E+ +K++ E E T F + H P ++S++ P E
Sbjct: 15 KMALDIEIAAYRKLL-----EGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPK 69
Query: 604 VMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYY 663
+ KF EE + EK E E L ++ +KEE ++A +E EEE
Sbjct: 70 LKVQHKFVEEIIEETKVEDEK--SEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEE 127
Query: 664 EEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQG 723
EE V++ + +T+ + E G EK++ ++ +
Sbjct: 128 EE-------------VAAKKSPVKATAPEVKEEEG------------EKEEEEGQEEEEE 162
Query: 724 DDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEA 770
+D + +SD+ EE GS EG+ + +G E+ + + EA
Sbjct: 163 ED-----EGAKSDQAEEGGSEKEGS-----SEKEEGEQEEGETEAEA 199
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 47.8 bits (112), Expect = 5e-05
Identities = 110/585 (18%), Positives = 217/585 (37%), Gaps = 88/585 (15%)
Query: 231 KEEERKKMEKLLAGEDGTSERRKSIKTYR---EIVQEKE--RRERELHEAYKNARSQEEA 285
K + + K E + + ++RR + R + ++E+E RR++E+ E + ++ +
Sbjct: 28 KGDVKDKFEAMQRAREERNQRRSRDEKQRRKEQYIREREWNRRKQEIKEMLASDDEEDVS 87
Query: 286 EGILQQYIERFTIS-EAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPK 344
+ + Y+ + T + + +E + E+ TE + K Q+ L
Sbjct: 88 SKVEKAYVPKLTGTVKGRFAEMEKQRQEEQRKRTEEERKRRIEQDMLEKRKIQRELAK-- 145
Query: 345 FTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDG 404
RA ++ + G+ S S+ + + P +K++K G
Sbjct: 146 ----------RAEQIEDINNTGTESASEEGDDSLLITVVP------------VKSYKTSG 183
Query: 405 KVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKK 464
K+ N E + +E E++ + Q + L L D+ IE KK
Sbjct: 184 KMKKNFEDLEKEREEKERIKYEEDKRIRYEEQR---PSLKEAKCLSLVMDD-EIESEAKK 239
Query: 465 PNSVPQELAATTEKTEPNSQEDKN----DGGKSRKGNIELASSEPQHFTTTVTRCSPTVA 520
+ P +L T E+ E QE++ + + R + A E + + A
Sbjct: 240 ESLSPGKLKLTFEELERQRQENRKKQAEEEARKRLEEEKRAFEEARRQMVNEDEENQDTA 299
Query: 521 FVEFPSSP-QLKNDVSE------EKDQKKPENEMSGKVEL-------VLSQKVVKPKSPE 566
+ P +LK E E +++K E E ++E VV SPE
Sbjct: 300 KIFKGYRPGKLKLSFEEMERQRREDEKRKAEEEARRRIEEEKKAFAEARRNMVVDDDSPE 359
Query: 567 PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQ 626
T++ FL P +++ L Q ++ K E E+ RQE +
Sbjct: 360 MYKTISQEFLT--PGKLEINFEELLKQKMEEEKRRTEEERKHKLEMEKQEFEQLRQEMGE 417
Query: 627 QEQERL---LQERYQK----------EQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDT 673
+E+E L Y++ + LK ++EK + E+E ++ EEER
Sbjct: 418 EEEENETFGLSREYEELIKLKRSGSIQAKNLKSKFEKIGQLSEKEIQKKIEEERA--RRR 475
Query: 674 VVPFTVSSSSA------DQLSTSSSMTEGSGTMNKIDL-------GNCQDEKQDRRWKKS 720
+ + A D + + + +K+++ ++E++ RR ++
Sbjct: 476 AIDLEIKEREAENFHEEDDVDVRPARKSEAPFTHKVNMKARFEQMAKAREEEEQRRIEEQ 535
Query: 721 ------FQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKG 759
F+ + D L+ + + EE+GS+ G+ A G
Sbjct: 536 KLLRMQFEQREIDAALQKKREEEEEEEGSIMNGSTAEDEEQTRSG 580
Score = 46.2 bits (108), Expect = 1e-04
Identities = 115/542 (21%), Positives = 212/542 (39%), Gaps = 107/542 (19%)
Query: 166 SDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVS 225
SDD E S E+A V + + + + Q +EE K ++ R+R +
Sbjct: 80 SDDEEDVSSK----VEKAYVPKLTGTVKGRFAEMEKQRQEEQRKRTEE-----ERKRRIE 130
Query: 226 QDLIKKEEERKKMEKLL--------AGEDGTSERR-----------KSIKT-------YR 259
QD+++K + ++++ K G + SE KS KT +
Sbjct: 131 QDMLEKRKIQRELAKRAEQIEDINNTGTESASEEGDDSLLITVVPVKSYKTSGKMKKNFE 190
Query: 260 EIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTE 319
++ +E+E +ER +E K R +E+ R ++ EA L M +E
Sbjct: 191 DLEKEREEKERIKYEEDKRIRYEEQ----------RPSLKEAKCLSLVMDDEIESE---- 236
Query: 320 PNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAV 379
+++SL P K T E + + +A
Sbjct: 237 ---------------AKKESLSPGKLKLTFEELERQRQENRKKQAEEEARKRLEEEKRAF 281
Query: 380 PMLTPKPYSQPKNSQDVLKTFKV--DGKVSVNGETVHRE--EEKERECPTVAPAHSLTKS 435
+ ++ + +QD K FK GK+ ++ E + R+ E+++R+ A +
Sbjct: 282 EEARRQMVNEDEENQDTAKIFKGYRPGKLKLSFEEMERQRREDEKRKAEEEARRRIEEEK 341
Query: 436 QMFEGVARV----HGSPLELKQDN------GSIEINIKK--PNSVPQELAATTEKTEPNS 483
+ F R SP K + G +EIN ++ + +E T E+ +
Sbjct: 342 KAFAEARRNMVVDDDSPEMYKTISQEFLTPGKLEINFEELLKQKMEEEKRRTEEERKHKL 401
Query: 484 QEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKP 543
+ +K + + R+ E+ E ++ T ++R E+ +LK S + K
Sbjct: 402 EMEKQEFEQLRQ---EMGEEEEENETFGLSR--------EYEELIKLKRSGSIQAKNLKS 450
Query: 544 ENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLD-KMPEANQLHLPN-----LNSQVDSP 597
+ E G+ LS+K ++ K E A L+ K EA H + + ++P
Sbjct: 451 KFEKIGQ----LSEKEIQKKIEEERARRRAIDLEIKEREAENFHEEDDVDVRPARKSEAP 506
Query: 598 SSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEE 657
+ K + F+ A EEE +R+ E+++LL R Q EQ ++ +K ++E EE
Sbjct: 507 FTHKVNMKARFEQMAKAREEEEQRRI----EEQKLL--RMQFEQREIDAALQKKREEEEE 560
Query: 658 EE 659
EE
Sbjct: 561 EE 562
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.126 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,998,027
Number of Sequences: 37866
Number of extensions: 2101641
Number of successful extensions: 25356
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 301
Number of HSP's successfully gapped in prelim test: 811
Number of HSP's that attempted gapping in prelim test: 12117
Number of HSP's gapped (non-prelim): 7968
length of query: 902
length of database: 18,247,518
effective HSP length: 111
effective length of query: 791
effective length of database: 14,044,392
effective search space: 11109114072
effective search space used: 11109114072
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.