Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 163310741
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|163310741 LIM and calponin homology domains 1 isoform a
[Homo sapiens]
(1083 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|163310741 LIM and calponin homology domains 1 isoform a [Homo... 2184 0.0
gi|163310743 LIM and calponin homology domains 1 isoform b [Homo... 2112 0.0
gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 2105 0.0
gi|163310747 LIM and calponin homology domains 1 isoform d [Homo... 1784 0.0
gi|163310749 LIM and calponin homology domains 1 isoform e [Homo... 1749 0.0
gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] 442 e-124
gi|221316634 LIM domain only 7 isoform 2 [Homo sapiens] 159 1e-38
gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens] 73 1e-12
gi|4502923 calponin 3 [Homo sapiens] 73 1e-12
gi|41327730 calponin 2 isoform b [Homo sapiens] 68 5e-11
gi|4758018 calponin 2 isoform a [Homo sapiens] 65 3e-10
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 61 7e-09
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 59 3e-08
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 56 2e-07
gi|238908501 sciellin isoform 3 [Homo sapiens] 56 2e-07
gi|238908499 sciellin isoform 1 [Homo sapiens] 56 2e-07
gi|238908497 sciellin isoform 2 [Homo sapiens] 56 2e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 55 4e-07
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 55 5e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 55 5e-07
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 52 2e-06
gi|148746195 trichohyalin [Homo sapiens] 50 1e-05
gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens] 49 2e-05
gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens] 49 2e-05
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 49 3e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 49 3e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 49 3e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 49 3e-05
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 49 3e-05
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 49 3e-05
>gi|163310741 LIM and calponin homology domains 1 isoform a [Homo
sapiens]
Length = 1083
Score = 2184 bits (5659), Expect = 0.0
Identities = 1083/1083 (100%), Positives = 1083/1083 (100%)
Query: 1 MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA 60
MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA
Sbjct: 1 MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA 60
Query: 61 IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS 120
IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS
Sbjct: 61 IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS 120
Query: 121 RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI 180
RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI
Sbjct: 121 RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI 180
Query: 181 DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR 240
DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR
Sbjct: 181 DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR 240
Query: 241 KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST 300
KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST
Sbjct: 241 KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST 300
Query: 301 ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE 360
ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE
Sbjct: 301 ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE 360
Query: 361 DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE 420
DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE
Sbjct: 361 DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE 420
Query: 421 RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL 480
RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL
Sbjct: 421 RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL 480
Query: 481 NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP 540
NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP
Sbjct: 481 NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP 540
Query: 541 YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG 600
YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG
Sbjct: 541 YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG 600
Query: 601 SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ 660
SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ
Sbjct: 601 SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ 660
Query: 661 HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE 720
HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE
Sbjct: 661 HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE 720
Query: 721 PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKW 780
PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKW
Sbjct: 721 PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKW 780
Query: 781 QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD 840
QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD
Sbjct: 781 QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD 840
Query: 841 QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT 900
QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT
Sbjct: 841 QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT 900
Query: 901 EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKT 960
EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKT
Sbjct: 901 EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKT 960
Query: 961 LPLDKSINHQIESPSERRKKSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPL 1020
LPLDKSINHQIESPSERRKKSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPL
Sbjct: 961 LPLDKSINHQIESPSERRKKSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPL 1020
Query: 1021 GKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQP 1080
GKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQP
Sbjct: 1021 GKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQP 1080
Query: 1081 TTL 1083
TTL
Sbjct: 1081 TTL 1083
>gi|163310743 LIM and calponin homology domains 1 isoform b [Homo
sapiens]
Length = 1057
Score = 2112 bits (5471), Expect = 0.0
Identities = 1057/1083 (97%), Positives = 1057/1083 (97%), Gaps = 26/1083 (2%)
Query: 1 MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA 60
MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA
Sbjct: 1 MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA 60
Query: 61 IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS 120
IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS
Sbjct: 61 IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS 120
Query: 121 RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI 180
RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI
Sbjct: 121 RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI 180
Query: 181 DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR 240
DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR
Sbjct: 181 DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR 240
Query: 241 KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST 300
KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST
Sbjct: 241 KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST 300
Query: 301 ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE 360
ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE
Sbjct: 301 ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE 360
Query: 361 DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE 420
DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE
Sbjct: 361 DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE 420
Query: 421 RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL 480
RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL
Sbjct: 421 RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL 480
Query: 481 NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP 540
NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP
Sbjct: 481 NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP 540
Query: 541 YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG 600
YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG
Sbjct: 541 YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG 600
Query: 601 SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ 660
SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ
Sbjct: 601 SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ 660
Query: 661 HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE 720
HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE
Sbjct: 661 HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE 720
Query: 721 PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKW 780
PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKW
Sbjct: 721 PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKW 780
Query: 781 QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD 840
QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD
Sbjct: 781 QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD 840
Query: 841 QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT 900
QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT
Sbjct: 841 QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT 900
Query: 901 EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKT 960
EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKT
Sbjct: 901 EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKT 960
Query: 961 LPLDKSINHQIESPSERRKKSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPL 1020
LPLDKSINHQIESPSERRK SISGKKLCSSCGLPL
Sbjct: 961 LPLDKSINHQIESPSERRK--------------------------SISGKKLCSSCGLPL 994
Query: 1021 GKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQP 1080
GKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQP
Sbjct: 995 GKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQP 1054
Query: 1081 TTL 1083
TTL
Sbjct: 1055 TTL 1057
>gi|163310745 LIM and calponin homology domains 1 isoform c [Homo
sapiens]
Length = 1056
Score = 2105 bits (5454), Expect = 0.0
Identities = 1056/1083 (97%), Positives = 1056/1083 (97%), Gaps = 27/1083 (2%)
Query: 1 MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA 60
MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA
Sbjct: 1 MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNA 60
Query: 61 IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS 120
IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS
Sbjct: 61 IKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYS 120
Query: 121 RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI 180
RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI
Sbjct: 121 RKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYI 180
Query: 181 DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR 240
DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR
Sbjct: 181 DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR 240
Query: 241 KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST 300
KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST
Sbjct: 241 KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST 300
Query: 301 ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE 360
ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE
Sbjct: 301 ATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE 360
Query: 361 DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE 420
DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE
Sbjct: 361 DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE 420
Query: 421 RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL 480
RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL
Sbjct: 421 RRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFL 480
Query: 481 NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP 540
NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP
Sbjct: 481 NDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP 540
Query: 541 YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG 600
YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG
Sbjct: 541 YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG 600
Query: 601 SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ 660
SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ
Sbjct: 601 SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ 660
Query: 661 HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE 720
HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE
Sbjct: 661 HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPE 720
Query: 721 PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKW 780
PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP FKFWAWDPEEERRRQEKW
Sbjct: 721 PEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP-FKFWAWDPEEERRRQEKW 779
Query: 781 QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD 840
QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD
Sbjct: 780 QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD 839
Query: 841 QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT 900
QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT
Sbjct: 840 QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT 899
Query: 901 EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKT 960
EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKT
Sbjct: 900 EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKT 959
Query: 961 LPLDKSINHQIESPSERRKKSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPL 1020
LPLDKSINHQIESPSERRK SISGKKLCSSCGLPL
Sbjct: 960 LPLDKSINHQIESPSERRK--------------------------SISGKKLCSSCGLPL 993
Query: 1021 GKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQP 1080
GKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQP
Sbjct: 994 GKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQP 1053
Query: 1081 TTL 1083
TTL
Sbjct: 1054 TTL 1056
>gi|163310747 LIM and calponin homology domains 1 isoform d [Homo
sapiens]
Length = 902
Score = 1784 bits (4620), Expect = 0.0
Identities = 895/922 (97%), Positives = 895/922 (97%), Gaps = 27/922 (2%)
Query: 162 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 221
KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV
Sbjct: 8 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 67
Query: 222 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 281
LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP
Sbjct: 68 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 127
Query: 282 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 341
APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP
Sbjct: 128 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 187
Query: 342 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 401
HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG
Sbjct: 188 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 247
Query: 402 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 461
TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE
Sbjct: 248 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 307
Query: 462 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 521
MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS
Sbjct: 308 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 367
Query: 522 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 581
GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA
Sbjct: 368 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 427
Query: 582 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 641
PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK
Sbjct: 428 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 487
Query: 642 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 701
NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM
Sbjct: 488 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 547
Query: 702 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 761
SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP
Sbjct: 548 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 607
Query: 762 QFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE 821
FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE
Sbjct: 608 -FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE 666
Query: 822 RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS 881
RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS
Sbjct: 667 RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS 726
Query: 882 DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS 941
DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS
Sbjct: 727 DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS 786
Query: 942 QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKKSPREHFQAGPFSPCSPTPPGQ 1001
QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRK
Sbjct: 787 QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRK---------------------- 824
Query: 1002 SPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIR 1061
SISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIR
Sbjct: 825 ----SISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIR 880
Query: 1062 NGLLNCNDCYMRSRSAGQPTTL 1083
NGLLNCNDCYMRSRSAGQPTTL
Sbjct: 881 NGLLNCNDCYMRSRSAGQPTTL 902
>gi|163310749 LIM and calponin homology domains 1 isoform e [Homo
sapiens]
Length = 890
Score = 1749 bits (4531), Expect = 0.0
Identities = 883/922 (95%), Positives = 883/922 (95%), Gaps = 39/922 (4%)
Query: 162 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 221
KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV
Sbjct: 8 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 67
Query: 222 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 281
LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP
Sbjct: 68 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 127
Query: 282 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 341
APLRKKKAEREEYRKSWSTATSPLGGERPFR STSMFDMRCEEEAAVQP
Sbjct: 128 APLRKKKAEREEYRKSWSTATSPLGGERPFR------------STSMFDMRCEEEAAVQP 175
Query: 342 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 401
HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG
Sbjct: 176 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 235
Query: 402 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 461
TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE
Sbjct: 236 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 295
Query: 462 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 521
MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS
Sbjct: 296 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 355
Query: 522 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 581
GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA
Sbjct: 356 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 415
Query: 582 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 641
PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK
Sbjct: 416 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 475
Query: 642 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 701
NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM
Sbjct: 476 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 535
Query: 702 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 761
SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP
Sbjct: 536 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 595
Query: 762 QFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE 821
FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE
Sbjct: 596 -FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE 654
Query: 822 RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS 881
RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS
Sbjct: 655 RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS 714
Query: 882 DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS 941
DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS
Sbjct: 715 DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS 774
Query: 942 QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKKSPREHFQAGPFSPCSPTPPGQ 1001
QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRK
Sbjct: 775 QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRK---------------------- 812
Query: 1002 SPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIR 1061
SISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIR
Sbjct: 813 ----SISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIR 868
Query: 1062 NGLLNCNDCYMRSRSAGQPTTL 1083
NGLLNCNDCYMRSRSAGQPTTL
Sbjct: 869 NGLLNCNDCYMRSRSAGQPTTL 890
>gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens]
Length = 1349
Score = 442 bits (1137), Expect = e-124
Identities = 331/986 (33%), Positives = 507/986 (51%), Gaps = 147/986 (14%)
Query: 31 IEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCK 90
I+ VT ++F KDFR LENG+LLC+L+N +KPG++KKINRL TPIAGLDNI +FL+ C+
Sbjct: 74 IKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIAGLDNINVFLKACE 133
Query: 91 ELGLKESQLFDPSDLQDTSNRVTVKSLDYSRKLKNVLVTIYWLGKAANSCTSYSGTTLNL 150
++GLKE+QLF P DLQD SNRVTVK + R++KNVL+T+YWLG+ A S Y+G LNL
Sbjct: 134 QIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKAQSNPYYNGPHLNL 193
Query: 151 KEFEGLLAQ-MRKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPR-HGRDDSFDSLDSF 208
K FE LL Q + K +D KRS RDSGY D W ER + L+PPR H R+DSF+SLDS
Sbjct: 194 KAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRHHKREDSFESLDSL 253
Query: 209 GSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQ 268
GSRS + S D+ LRG +G SD++S+ K+ D KDDMS RR S EPK+A+PFN+
Sbjct: 254 GSRSLTSCSSDITLRGGREGFESDTDSEFTF-KMQDYNKDDMSYRRISAVEPKTALPFNR 312
Query: 269 YLPNKSNQTAYVPAPLRKKKAER-EEYRKSWSTATSPLGGERPFRYGPR-TPVSDDAEST 326
+LPNKS Q +YVPAPLRKKK ++ E+ R+SW+ SP+ E + + + S
Sbjct: 313 FLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWA---SPVYTEADGTFSRLFQKIYGENGSK 369
Query: 327 SMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKE 386
SM D+ E+ VQ + R E++Q I +QL+E+D KWQDDLA+WK RR+S + DL KK+
Sbjct: 370 SMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKK 426
Query: 387 EERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ- 445
EER+++EK + ++S KT++E++Q++E + ++ + R + +L++
Sbjct: 427 EEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK--STVPSRRRMYSFDDVLEEG 479
Query: 446 -YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLNDPNPMK---YLRQQSLPPPKF 499
T+SEA ER+E S + + ++F + + L QS +
Sbjct: 480 KRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQS 539
Query: 500 TATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPMLTPKPY-SQPKNSQDVLKTFKV 556
A++ + +R++ ++++ + S S KT T + ++TP+P+ SQ + + +++ +
Sbjct: 540 PASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTM 599
Query: 557 DGKVSVNG---------------------------------ETVHREEEKERECPTVAPA 583
D NG E EE+ R +P
Sbjct: 600 DDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPF 659
Query: 584 HSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKN 642
SL++ Q A + S L+L ++G EI S +E++ + ++
Sbjct: 660 SSLSQDQAATSKATLSSTSGLDLMSESGEGEI------SPQREVSRSQDQFSDMRISINQ 713
Query: 643 DGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQ---LKNDVSEEKDQKKPEN 699
GKS + P F +V SP F + + + N D K+ E
Sbjct: 714 TPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVDDEIIAINNTKFSYNDSKEWEE 772
Query: 700 EMSGKVE---LVLS-QKVVKPKSPEPE----------------ATLTFPFLDKMPEAN-- 737
M+ E LV+ ++ K SPE + ++T F + + +N
Sbjct: 773 AMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIE 832
Query: 738 --------------------QLHLPNL--NSQVDSPSSEKS-----PVMT---PQFKFWA 767
+ L NL SQ S S PV T P W
Sbjct: 833 SKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVW- 891
Query: 768 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 827
D EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A++E E E +Y +EE ++
Sbjct: 892 -DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS 950
Query: 828 TVVPFTV--------------SSSSADQLSTSSSMTEGSGTMNKI---DLG-NCQDE--- 866
+ T S S+D+ T + E ++ D G QD+
Sbjct: 951 NSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVI 1010
Query: 867 KQDRRWKKSFQGDDSDLLLKTRESDR 892
+++R+W++ Q + L+ ++
Sbjct: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQ 1036
Score = 123 bits (308), Expect = 1e-27
Identities = 101/349 (28%), Positives = 161/349 (46%), Gaps = 46/349 (13%)
Query: 771 EEERRRQEKWQQEQERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDT 828
E ER+ +++ Q+EQE Q+R Q E ++ K E +K Q E+E E + R+ ++
Sbjct: 1011 ERERKWEQQLQEEQE---QKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSY 1067
Query: 829 VVPFTVSSSS----ADQLSTSSS------MTEGSGTMNKID-LGNC-------------- 863
+P T +SS D+ + S+ T +G +D +GN
Sbjct: 1068 DIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPS 1127
Query: 864 ------QDEKQDRRWKKSFQGDDSDLLLKTRESDR--LEEKGSLTEG-ALAHSGNPVSKG 914
Q Q+ R + D+S + ++ ++ + G + G +L + +P S
Sbjct: 1128 GAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNS 1187
Query: 915 VHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESP 974
+ L+ G + ++ P Q TSN + P S+
Sbjct: 1188 WRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGV 1247
Query: 975 SERRKKSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLY 1034
+ + +PR H SP + Q NRS+SGK++CS C LGKGAAMIIE+L L
Sbjct: 1248 ATTQSPTPRSH------SPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLC 1301
Query: 1035 FHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1083
+H+ CF+C C+ LG + SG +VRIRN L CNDCY+R +S G+PT +
Sbjct: 1302 YHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLRFKS-GRPTAM 1349
Score = 31.6 bits (70), Expect = 4.2
Identities = 58/271 (21%), Positives = 102/271 (37%), Gaps = 39/271 (14%)
Query: 324 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 383
E ++ + +EE + +EQ + Q R+ + + + + ++ RR S D+
Sbjct: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1070
Query: 384 KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 435
K EE +R K +D ++ + + K +I + R E + +
Sbjct: 1071 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1129
Query: 436 QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 478
+ E + ILQ+ +R + + E + +P I+ R S + NL S
Sbjct: 1130 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1188
Query: 479 ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 531
+LN P ++ S PPP+ +T R +S+ S KT T
Sbjct: 1189 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1246
Query: 532 AVPMLTPKPYS-QPKNSQ--DVLKTFKVDGK 559
+P P S P SQ L+ V GK
Sbjct: 1247 VATTQSPTPRSHSPSASQSGSQLRNRSVSGK 1277
>gi|221316634 LIM domain only 7 isoform 2 [Homo sapiens]
Length = 1385
Score = 159 bits (402), Expect = 1e-38
Identities = 190/767 (24%), Positives = 329/767 (42%), Gaps = 152/767 (19%)
Query: 246 KKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPL 305
KKDDM R+ + + VP + P ++ A L++ +A RE R L
Sbjct: 351 KKDDMLTRKIQSWKLGTTVPPISFTPGPCSE-----ADLKRWEAIREASRLRHKKR---L 402
Query: 306 GGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQ 365
ER F+ + + S SM D+ E+ VQ + R E++Q I +QL+E+D KWQ
Sbjct: 403 MVERLFQ-----KIYGENGSKSMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQ 454
Query: 366 DDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERE 425
DDLA+WK RR+S + DL KK+EER+++EK + ++S KT++E++Q++E + ++
Sbjct: 455 DDLAKWKDRRKSYTSDLQKKKEEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK 509
Query: 426 LHEAYKNARSQEEAEGILQQ--YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLN 481
+ R + +L++ T+SEA ER+E S + + ++F
Sbjct: 510 --STVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAK 567
Query: 482 DPNPMK---YLRQQSLPPPKFTATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPML 536
+ + L QS + A++ + +R++ ++++ + S S KT T + ++
Sbjct: 568 REDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVV 627
Query: 537 TPKPY-SQPKNSQDVLKTFKVDGKVSVNG------------------------------- 564
TP+P+ SQ + + +++ +D NG
Sbjct: 628 TPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSS 687
Query: 565 --ETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNS 621
E EE+ R +P SL++ Q A + S L+L ++G EI S
Sbjct: 688 QKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEI------S 741
Query: 622 VPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSS 681
+E++ + ++ GKS + P F +V SP F +
Sbjct: 742 PQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVD 800
Query: 682 PQ---LKNDVSEEKDQKKPENEMSGKVE---LVLS-QKVVKPKSPEPE------------ 722
+ + N D K+ E M+ E LV+ ++ K SPE +
Sbjct: 801 DEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSE 860
Query: 723 ----ATLTFPFLDKMPEAN----------------------QLHLPNL--NSQVDSPSSE 754
++T F + + +N + L NL SQ S
Sbjct: 861 KSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSS 920
Query: 755 KS-----PVMT---PQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKA 806
S PV T P W D EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A
Sbjct: 921 DSVVPDLPVPTISAPSRWVW--DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRA 978
Query: 807 QKEVEEEERRYYEEERKIIEDTVVPFTV--------------SSSSADQLSTSSSMTEGS 852
++E E E +Y +EE ++ + T S S+D+ T + E
Sbjct: 979 KQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERR 1038
Query: 853 GTMNKI---DLG-NCQDE---KQDRRWKKSFQGDDSDLLLKTRESDR 892
++ D G QD+ +++R+W++ Q + L+ ++
Sbjct: 1039 QPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQ 1085
Score = 77.0 bits (188), Expect = 9e-14
Identities = 36/60 (60%), Positives = 48/60 (80%), Gaps = 1/60 (1%)
Query: 242 LPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAER-EEYRKSWST 300
+ D KDDMS RR S EPK+A+PFN++LPNKS Q +YVPAPLRKKK ++ E+ R+SW++
Sbjct: 1 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 60
Score = 38.1 bits (87), Expect = 0.045
Identities = 18/54 (33%), Positives = 37/54 (68%)
Query: 770 PEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERK 823
P+EE +++ ++ Q++L+ ER +K + +L+EE E+ + + E EE++ EE+K
Sbjct: 1040 PQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQK 1093
Score = 37.4 bits (85), Expect = 0.077
Identities = 62/264 (23%), Positives = 110/264 (41%), Gaps = 27/264 (10%)
Query: 776 RQEKWQQE-QERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDTVVPF 832
R+ KW+Q+ QE Q+R Q E ++ K E +K Q E+E E + R+ ++ +P
Sbjct: 1061 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPK 1120
Query: 833 TVSSSS----ADQLSTSSS------MTEGSGTMNKID-LGNCQDEKQDRRWKKSFQG--- 878
T +SS D+ + S+ T +G +D +GN ++ + ++ G
Sbjct: 1121 TEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAEL 1180
Query: 879 DDSDLLLKTRESDRLEEKGS-LTEGALAHSGNPVS-KGVHEDHQLDTEAGAPHCGTNPQL 936
+ +L + R+ L S + + + + + PVS G+ + +P +
Sbjct: 1181 ERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNS---W 1237
Query: 937 AQDPSQNQQTSNPTHSS--EDVKPKTLPLDKSINHQIESPSER---RKKSPREHFQAGPF 991
Q P NQ T SS + +P + S + +PS + G
Sbjct: 1238 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVA 1297
Query: 992 SPCSPTPPGQSPNRSISGKKLCSS 1015
+ SPTP SP+ S SG +L +S
Sbjct: 1298 TTQSPTPRSHSPSASQSGSQLRNS 1321
Score = 36.2 bits (82), Expect = 0.17
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 207 SFGSRSRQTPSPDV----VLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKS 262
+F S R+ +V ++G+S E R +P++ KDD+ R+ S P
Sbjct: 69 TFSSNQRRIWGTNVENWPTVQGTSKSSCYLEEEKAKTRSIPNIVKDDLYVRKLSPVMPNP 128
Query: 263 AVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSW 298
F+Q+LP + P + K+ +RE Y K W
Sbjct: 129 GNAFDQFLPK-----CWTPEDVNWKRIKRETY-KPW 158
Score = 33.1 bits (74), Expect = 1.5
Identities = 61/301 (20%), Positives = 112/301 (37%), Gaps = 37/301 (12%)
Query: 324 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 383
E ++ + +EE + +EQ + Q R+ + + + + ++ RR S D+
Sbjct: 1060 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1119
Query: 384 KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 435
K EE +R K +D ++ + + K +I + R E + +
Sbjct: 1120 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1178
Query: 436 QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 478
+ E + ILQ+ +R + + E + +P I+ R S + NL S
Sbjct: 1179 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1237
Query: 479 ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 531
+LN P ++ S PPP+ +T R +S+ S KT T
Sbjct: 1238 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1295
Query: 532 AVPMLTPKPYS-QPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQ 590
+P P S P SQ + VSV E + +E + E +++ S
Sbjct: 1296 VATTQSPTPRSHSPSASQSGSQLRNSVLPVSVTSEALPQELKSGSETTNCTATTAISDSN 1355
Query: 591 M 591
+
Sbjct: 1356 L 1356
>gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens]
Length = 297
Score = 73.2 bits (178), Expect = 1e-12
Identities = 37/91 (40%), Positives = 58/91 (63%), Gaps = 1/91 (1%)
Query: 26 EAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILF 85
E ++WIE VTGR G+ +F GL++GI+LCE +N ++PG VKKIN L+NI F
Sbjct: 33 ELREWIEGVTGRRIGN-NFMDGLKDGIILCEFINKLQPGSVKKINESTQNWHQLENIGNF 91
Query: 86 LRGCKELGLKESQLFDPSDLQDTSNRVTVKS 116
++ + G+K +F+ +DL + +N V+S
Sbjct: 92 IKAITKYGVKPHDIFEANDLFENTNHTQVQS 122
>gi|4502923 calponin 3 [Homo sapiens]
Length = 329
Score = 73.2 bits (178), Expect = 1e-12
Identities = 36/94 (38%), Positives = 59/94 (62%), Gaps = 1/94 (1%)
Query: 23 AFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNI 82
A + + WIE+VTG S G +F+ GL++GI+LCEL+N ++PG VKK+N L+NI
Sbjct: 28 AEEDLRNWIEEVTGMSIGP-NFQLGLKDGIILCELINKLQPGSVKKVNESSLNWPQLENI 86
Query: 83 ILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKS 116
F++ + G+K +F+ +DL + N V++
Sbjct: 87 GNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQT 120
>gi|41327730 calponin 2 isoform b [Homo sapiens]
Length = 270
Score = 67.8 bits (164), Expect = 5e-11
Identities = 43/125 (34%), Positives = 65/125 (52%), Gaps = 15/125 (12%)
Query: 25 SEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIIL 84
+E + WIE +TG S G DF+ GL++G +LC L+N ++PG V KINR L+N+
Sbjct: 32 AELRTWIEGLTGLSIGP-DFQKGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQLENLSN 90
Query: 85 FLRGCKELGLKESQLFDPSDLQDTSN--RVTVKSLDYSRKLKNVLVTIYWLGKAANSCTS 142
F++ G+ LF+ +DL ++ N +V V L + K+ N C S
Sbjct: 91 FIKAMVSYGMNPVDLFEANDLFESGNMTQVQVSLLALAGKM------------GTNKCAS 138
Query: 143 YSGTT 147
SG T
Sbjct: 139 QSGMT 143
>gi|4758018 calponin 2 isoform a [Homo sapiens]
Length = 309
Score = 65.5 bits (158), Expect = 3e-10
Identities = 34/91 (37%), Positives = 54/91 (59%), Gaps = 1/91 (1%)
Query: 25 SEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIIL 84
+E + WIE +TG S G DF+ GL++G +LC L+N ++PG V KINR L+N+
Sbjct: 32 AELRTWIEGLTGLSIGP-DFQKGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQLENLSN 90
Query: 85 FLRGCKELGLKESQLFDPSDLQDTSNRVTVK 115
F++ G+ LF+ +DL ++ N V+
Sbjct: 91 FIKAMVSYGMNPVDLFEANDLFESGNMTQVQ 121
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 60.8 bits (146), Expect = 7e-09
Identities = 100/529 (18%), Positives = 212/529 (40%), Gaps = 62/529 (11%)
Query: 332 RCEEEAAVQPHS-RARQEQLQLINNQLREEDDKWQDD---LARWKSRRRSVSQDLIKKEE 387
R EEE Q R ++E++ +LRE++ K ++ + R + R R ++L ++E+
Sbjct: 276 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEK 335
Query: 388 ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE----RRERELHEAYKNARSQE------ 437
E ++ ++L E+ E+ + + E ++E+E R+E L E K R QE
Sbjct: 336 ELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 395
Query: 438 -----EAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQ 492
E + L++ ER E + E++E + ++ E + +R++
Sbjct: 396 EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRER 455
Query: 493 SLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLK 552
K ET + + K + +P K + Q K + K
Sbjct: 456 E---KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512
Query: 553 TFKVDGKVSVNGETVHRE-----EEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQ 607
++ + K+ E +E +EK RE + QM+E ++ ++
Sbjct: 513 IWEQEEKIRDQEEMWGQEKKMWRQEKMRE----------QEDQMWEQEEKMRDQEQKMWD 562
Query: 608 DNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVT 667
+E ++ QE ++ + +E + K + E+ + +
Sbjct: 563 QEERMEKKTQE-----QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 617
Query: 668 RCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTF 727
+ + K EEK Q++ E + ++ ++ + + PE
Sbjct: 618 KMQ----------EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667
Query: 728 PFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEER-----RRQEKWQQ 782
+KM E ++ + EK T + + WD E+ R R +EK +
Sbjct: 668 WEHEKMQEQEKMQ----EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMR 723
Query: 783 EQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVP 831
E+E +++E+ +K Q++ +E+ ++ ++E+ E+E + +E+E K+ E +P
Sbjct: 724 EEEEMMREQEEKMQEQ-EEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP 771
Score = 47.8 bits (112), Expect = 6e-05
Identities = 45/203 (22%), Positives = 90/203 (44%), Gaps = 22/203 (10%)
Query: 709 LSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAW 768
++ + +K K+ E + L P + QL++ L +++ V T + W
Sbjct: 218 ITNEELKKKNAELQEKL--PLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMW 275
Query: 769 DPEEERRRQEKWQQEQERLL---QERYQKEQDKLKEEWEK---AQKEVEEEERRYYEEER 822
EEE R QEK ++QE + +ER ++++ K++E+ EK +K + E+E+ E+E+
Sbjct: 276 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEK 335
Query: 823 KIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEK----QDRRWKKSFQG 878
++ E + M E M + Q+EK ++R W++ Q
Sbjct: 336 ELREQK----ELREQEEQMQEQEEKMWEQEEKMRE------QEEKMWRQEERLWEQEKQM 385
Query: 879 DDSDLLLKTRESDRLEEKGSLTE 901
+ + ++ +E E+ L E
Sbjct: 386 REQEQKMRDQEERMWEQDERLRE 408
Score = 45.8 bits (107), Expect = 2e-04
Identities = 80/511 (15%), Positives = 196/511 (38%), Gaps = 42/511 (8%)
Query: 344 RARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKK-MEKLLAGEDGT 402
R ++E++ + +LRE++++ ++ W+ + + ++++E++ + E+ + E+
Sbjct: 393 RDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERI 452
Query: 403 SERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEM 462
ER K ++ E ++E+E + ++ E +E + L + E+ E + E+ E
Sbjct: 453 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE- 511
Query: 463 PKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSG 522
KI E+ + + + + + + + + D
Sbjct: 512 -KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD-------- 562
Query: 523 SPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAP 582
+ K K + Q + ++ + + + K+ E + +EEK +E
Sbjct: 563 --QEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQ 620
Query: 583 AHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKN 642
+ E + E ++ E + + +P++ E + QE
Sbjct: 621 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQ 680
Query: 643 DGGKS--RKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENE 700
+ + + +E + E + T + + E + + ++ E+++K E E
Sbjct: 681 EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQE 740
Query: 701 --MSGKVELVLSQKVVKPKSPE--------PEATLTFPFLDKMPEANQL---------HL 741
M + E + Q+ + E PE +KM E ++
Sbjct: 741 EKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQE 800
Query: 742 PNLNSQVDSPSSEKSPVMTPQFKFWA-----WDPEEERRRQEKWQQEQERLLQERYQKEQ 796
+ Q + ++ + + K W W EE+ QE+ QE ++E+ Q ++
Sbjct: 801 EKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQE 860
Query: 797 DKLKEEWEK---AQKEVEEEERRYYEEERKI 824
+K++E+ EK ++++ E+E + +E KI
Sbjct: 861 EKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 45.4 bits (106), Expect = 3e-04
Identities = 40/225 (17%), Positives = 98/225 (43%), Gaps = 20/225 (8%)
Query: 690 EEKDQK-KPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPN----- 743
E++DQ + E +M + + + Q+ K + + T+ +KM E ++
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 744 ----LNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKL 799
+ Q + ++ + + K W + + + + ++ W+QE++ QE EQ +L
Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL 660
Query: 800 KEEWEK--------AQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEG 851
E+ EK Q++++E+E + +E+E+ +E + +++ SM E
Sbjct: 661 PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEK--MEKKTQEQEKKTWDQEKMREEESMRER 718
Query: 852 SGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEK 896
M + + + E++ + ++ Q + ++ + + EEK
Sbjct: 719 EKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK 763
Score = 45.4 bits (106), Expect = 3e-04
Identities = 35/162 (21%), Positives = 73/162 (45%), Gaps = 8/162 (4%)
Query: 285 RKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSR 344
R +K +E+ +K+W ER + ++ M+ +EE + +
Sbjct: 566 RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEK 625
Query: 345 A--RQEQLQLINNQLREEDDK-WQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 401
++E++Q ++ E+++K W+ + W+ +R ++ + + E+ ++ EK+ E+
Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEK 685
Query: 402 TSERRKSIKTYREIV-----QEKERRERELHEAYKNARSQEE 438
E+ K K +E QEK R E + E K R +EE
Sbjct: 686 IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Score = 43.9 bits (102), Expect = 8e-04
Identities = 30/140 (21%), Positives = 66/140 (47%), Gaps = 17/140 (12%)
Query: 768 WDPEEERRRQEK---------WQQEQERLLQERYQKEQDKLKEEWEK--AQKEVEEEERR 816
W+ E++ R QE+ W+Q++ +E +EQ+K+ E+ EK +K+++E+E++
Sbjct: 379 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKK 438
Query: 817 YYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSF 876
++E K+ E+ + +M E M K + E++++ W++
Sbjct: 439 TRDQEEKMQEEE----RIREREKKMREEEETMREQEEKMQKQE--ENMWEQEEKEWQQQR 492
Query: 877 QGDDSDLLLKTRESDRLEEK 896
+ + L + + EEK
Sbjct: 493 LPEQKEKLWEQEKMQEQEEK 512
Score = 43.5 bits (101), Expect = 0.001
Identities = 30/147 (20%), Positives = 72/147 (48%), Gaps = 9/147 (6%)
Query: 331 MRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERK 390
+R +EE Q RQE+++ +Q+ E+++K +D + + + + ++E++
Sbjct: 520 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTW 579
Query: 391 KMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAY---------KNARSQEEAEG 441
E+ + E+ ER K ++ E+++E+E + +E E + + QE+ E
Sbjct: 580 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEK 639
Query: 442 ILQQYIERFTISEAVLERLEMPKILER 468
+ +Q + + E + E+ +P+ E+
Sbjct: 640 MWEQEEKMWEQEEKMWEQQRLPEQKEK 666
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/137 (24%), Positives = 67/137 (48%), Gaps = 23/137 (16%)
Query: 769 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVE---EEERRYYEEERKII 825
+ EE R QE+ QEQE E+ Q++++K+ E+ EK Q++ E E+E + +E+E K+
Sbjct: 600 EEEEMMREQEEKMQEQE----EKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 655
Query: 826 EDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRW-KKSFQGDDSDLL 884
E +P ++L M E E++++ W ++ + +
Sbjct: 656 EQQRLP-----EQKEKLWEHEKMQEQEK----------MQEQEEKIWEQEKMEKKTQEQE 700
Query: 885 LKTRESDRLEEKGSLTE 901
KT + +++ E+ S+ E
Sbjct: 701 KKTWDQEKMREEESMRE 717
Score = 38.9 bits (89), Expect = 0.027
Identities = 32/127 (25%), Positives = 64/127 (50%), Gaps = 5/127 (3%)
Query: 771 EEER-RRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTV 829
EEER R +EK +E+E ++E+ +K Q + + WE+ +KE +++ R E++ K+ E
Sbjct: 448 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ--RLPEQKEKLWEQEK 505
Query: 830 VPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRE 889
+ +Q E G K+ E++D+ W++ + D + + +E
Sbjct: 506 MQ-EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 564
Query: 890 SDRLEEK 896
+R+E+K
Sbjct: 565 -ERMEKK 570
Score = 38.5 bits (88), Expect = 0.035
Identities = 30/175 (17%), Positives = 83/175 (47%), Gaps = 16/175 (9%)
Query: 284 LRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHS 343
LR+K+ E K W E+ + + + + T + + +EE ++
Sbjct: 406 LREKEERMREQEKMW---------EQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRERE 456
Query: 344 RARQEQLQLINNQ----LREEDDKWQDDLARWKSRRRSVSQD-LIKKEEERKKMEKLLAG 398
+ +E+ + + Q ++E++ W+ + W+ +R ++ L ++E+ +++ EK+
Sbjct: 457 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ 516
Query: 399 EDGTSERRKSIKTYREIVQEKERRERE--LHEAYKNARSQEEAEGILQQYIERFT 451
E+ ++ + +++ ++++ RE+E + E + R QE+ ++ +E+ T
Sbjct: 517 EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKT 571
Score = 35.8 bits (81), Expect = 0.23
Identities = 20/99 (20%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
Query: 334 EEEAAVQPHSRARQEQLQLINNQLRE----EDDKWQDDLARWKSRRRSVSQDLIKKEEER 389
EEE ++ QEQ + + Q E E+ W+ + W+ +R ++ + + E+
Sbjct: 724 EEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 783
Query: 390 KKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHE 428
++ EK+ E+ ++ + ++ E ++ +E + R E
Sbjct: 784 QEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEE 822
Score = 35.0 bits (79), Expect = 0.38
Identities = 29/133 (21%), Positives = 64/133 (48%), Gaps = 9/133 (6%)
Query: 769 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDT 828
+ EE+ + QE+ EQE ++E+ +K + + WE+ ++ E+E++ +EER +D
Sbjct: 345 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 404
Query: 829 VVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTR 888
+ +++ M E M + + + EK+ R ++ Q ++ ++ R
Sbjct: 405 RL-----REKEERMREQEKMWEQVEKMRE-EKKMQEQEKKTRDQEEKMQEEER---IRER 455
Query: 889 ESDRLEEKGSLTE 901
E EE+ ++ E
Sbjct: 456 EKKMREEEETMRE 468
Score = 33.5 bits (75), Expect = 1.1
Identities = 25/125 (20%), Positives = 64/125 (51%), Gaps = 10/125 (8%)
Query: 331 MRCEEEAAVQPHSRARQEQLQLINNQ-LREEDDKWQDDLARWKSRRRSVSQDLIKKEEE- 388
MR +EE + R R+++ ++ + + E+ +K +++ + +++ Q+ +EEE
Sbjct: 392 MRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEER 451
Query: 389 -RKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRE-------RELHEAYKNARSQEEAE 440
R++ +K+ E+ E+ + ++ E + E+E +E + + ++ + QE+ E
Sbjct: 452 IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 511
Query: 441 GILQQ 445
I +Q
Sbjct: 512 KIWEQ 516
Score = 32.3 bits (72), Expect = 2.5
Identities = 22/99 (22%), Positives = 47/99 (47%), Gaps = 6/99 (6%)
Query: 331 MRCEEEAAVQPHSRARQEQLQLINNQLREEDDK-WQDDLARWKSRRRSVSQDLIKKEEER 389
MR +EE R ++E+++ ++R +++K W + W + Q+ +E
Sbjct: 796 MRDQEEKM-----RGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEE 850
Query: 390 KKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHE 428
K EK+ E+ E+ + ++ E ++E+E + R E
Sbjct: 851 KMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEE 889
Score = 31.2 bits (69), Expect = 5.5
Identities = 26/142 (18%), Positives = 66/142 (46%), Gaps = 2/142 (1%)
Query: 322 DAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLRE-EDDKWQDDLARWKSRRRSVSQ 380
+AE + E++ +Q + + + +L+ L + + + Q+++ R + R +
Sbjct: 227 NAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEK 286
Query: 381 DLIKKEEERKKMEKLLAGEDGTS-ERRKSIKTYREIVQEKERRERELHEAYKNARSQEEA 439
+ K+EE+ + E+ L ++G E+ + + + ++E+E+ RE + + + E
Sbjct: 287 KIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQ 346
Query: 440 EGILQQYIERFTISEAVLERLE 461
E +Q+ E+ E + E
Sbjct: 347 EEQMQEQEEKMWEQEEKMREQE 368
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 58.5 bits (140), Expect = 3e-08
Identities = 171/858 (19%), Positives = 328/858 (38%), Gaps = 142/858 (16%)
Query: 90 KELGLKESQLFDPSDLQDTSNRVTVKSLDYSRKLKNVLVTIYWLGKAANSCTSYSGTTLN 149
+E L + Q+ D D S RVT L R K L T
Sbjct: 377 REKDLAQQQMQSDLDKADLSARVTELGLAVKRLEKQNL----------EKDQVNKDLTEK 426
Query: 150 LKEFEGLLAQMRK--DTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDS 207
L+ E L Q + +T+D E ++++RD DSE LS D S SL
Sbjct: 427 LEALESLRLQEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTADASNGSLR- 485
Query: 208 FGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFN 267
G ++TPSP R SS GRG R+ P A
Sbjct: 486 -GLSGQRTPSPP---RRSSPGRG-----------------------RSPRRGPSPAC--- 515
Query: 268 QYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTS 327
+ S+ A + + L K++ + ++ R + + LG R +SD
Sbjct: 516 ----SDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLG-------TLRKQLSDSESERR 564
Query: 328 MFD-----MRCEEEAAVQPHSRARQE--QLQLINNQLREEDD---------KWQDDLARW 371
+ +R + + A+Q H A++E +L+ N L E + Q + R
Sbjct: 565 ALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQ 624
Query: 372 KSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRE------RE 425
+ + +Q+ ++++ +R + E+ A +DG RR+ +++R++ Q + +R E
Sbjct: 625 EREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVE 684
Query: 426 LHEAYKNARSQEEAEGILQQYIERFTISEAVLE----RLEMPKILERSHSTEPNLSSFLN 481
+ EA A Q + +LQ E+ ++EA+ + R+E+ + + + E +L L+
Sbjct: 685 VREALSRATLQRD---MLQ--AEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLS 739
Query: 482 DPNPM-KYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKP 540
+ + + L Q L + A L+ SA G + V +
Sbjct: 740 KLSALNESLAQDKLDLNRLVAQ----------LEEEKSALQGRQRQAEQEATVAREEQER 789
Query: 541 YSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG 600
+ + Q+V + ++G + V + +E E++ PT+ S + Q+ + ++ G
Sbjct: 790 LEELRLEQEVARQ-GLEGSLRVAEQA---QEALEQQLPTLRHERSQLQEQLAQLSRQLSG 845
Query: 601 SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQ 660
EL+Q + ++ +E A K G + + + A E +
Sbjct: 846 REQELEQARREAQRQVEALERAAREKEALA----------KEHAGLAVQ--LVAAEREGR 893
Query: 661 HFTTTVTRCSPTVAFVE---FPSSPQLKNDVSEEKDQKKPENE--------MSGKVELVL 709
+ TR +E F QL + ++Q + E + ++G++ +
Sbjct: 894 TLSEEATRLRLEKEALEGSLFEVQRQLA-QLEARREQLEAEGQALLLAKETLTGELAGLR 952
Query: 710 SQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWD 769
Q + + + L K+ +A + +L Q + + + + W
Sbjct: 953 QQIIATQEKASLDKEL---MAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWREL 1009
Query: 770 PEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTV 829
E + Q + Q+EQE LL R + E+++L EE Q+E +E ++ ++
Sbjct: 1010 EAERAQLQSQLQREQEELL-ARLEAEKEELSEEIAALQQE---------RDEGLLLAESE 1059
Query: 830 VPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRE 889
+S +++ + S + GT + + + + E+Q R + + D S + T E
Sbjct: 1060 KQQALSLKESEKTALSEKL---MGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSE 1116
Query: 890 SDRLEEKGSLTEGALAHS 907
L + E A AH+
Sbjct: 1117 LRDL--RAQREEAAAAHA 1132
Score = 32.0 bits (71), Expect = 3.2
Identities = 52/277 (18%), Positives = 112/277 (40%), Gaps = 28/277 (10%)
Query: 735 EANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQERLLQER--Y 792
E Q + L S + S EKS + + EE R+ +EK Q QE L ++R
Sbjct: 585 EDAQREVQRLRSANELLSREKSN-LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRL 643
Query: 793 QKEQDKLKEEWEKAQKEVEEEERR--YYEEERKIIEDTVVPFTVSSS---------SADQ 841
++EQ+ ++ + ++E+E R+ E +R ++ +V + S A++
Sbjct: 644 EEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEK 703
Query: 842 LSTSSSMTEGSGTMNKIDLGNC-----QDEKQDRRWKKSFQGDD--SDLLLKTRESDRLE 894
+ ++T+ +++L + QD K S + D L R +LE
Sbjct: 704 AEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLE 763
Query: 895 EKGSLTEGALAHSGNPVSKGVHEDH-----QLDTEAGAPHCGTNPQLAQDPSQNQQTSNP 949
E+ S +G + + E +L+ E + ++A+ + + P
Sbjct: 764 EEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLP 823
Query: 950 T--HSSEDVKPKTLPLDKSINHQIESPSERRKKSPRE 984
T H ++ + L + ++ + + + R+++ R+
Sbjct: 824 TLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQ 860
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 56.2 bits (134), Expect = 2e-07
Identities = 132/620 (21%), Positives = 228/620 (36%), Gaps = 66/620 (10%)
Query: 383 IKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGI 442
+K EE+ K +EK E+ + + E+ +E+E+ +E + +EEAEG
Sbjct: 438 VKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGG 497
Query: 443 LQQY----IERFTISE-----AVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQS 493
++ E E V E + P + E + + P K ++
Sbjct: 498 EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 557
Query: 494 LPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKT 553
P + E A++ A SP K +P +P P+ ++ +K
Sbjct: 558 AKSPPEAKSPEKEEAKS-------PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKE 610
Query: 554 FKVDGKVSVNGETVHREEEKE-RECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSI 612
+ K ++ +EE K E + A S TK + + + E +
Sbjct: 611 ---EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEA-KSPEKAKSPEKEEAKSPEKA 666
Query: 613 EINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPT 672
+ +K P E A + K E S E K + E A S + + +
Sbjct: 667 KSPVKAEAKSP-EKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725
Query: 673 VAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDK 732
V E + + K+ V EE K PE S + L K + K+P E + DK
Sbjct: 726 VK-EEAKTPEKAKSPVKEE--AKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARS--PADK 780
Query: 733 MPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEE--RRRQEKWQQEQERLLQE 790
PE + + +V SP KSP+ K A PE+E ++ + K ++E QE
Sbjct: 781 FPEKAK---SPVKEEVKSPEKAKSPL-----KEDAKAPEKEIPKKEEVKSPVKEEEKPQE 832
Query: 791 RYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTE 850
KE K EE EKA + EE++ ++E ++ P S E
Sbjct: 833 VKVKEPPKKAEE-EKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE 891
Query: 851 GSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNP 910
++E +D++ K ++ ++ +E + +EK TE A +
Sbjct: 892 AK-----------KEEAEDKK-KVPTPEKEAPAKVEVKEDAKPKEK---TEVAKKEPDDA 936
Query: 911 VSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQT------SNPTHSSEDVKPKTLPLD 964
+K + + EA T + A+ P + +T + T S E KPK +
Sbjct: 937 KAKEPSKPAE-KKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAE 995
Query: 965 KSINHQIESPSERRKKSPRE 984
KS S ++++ P E
Sbjct: 996 KS------SSTDQKDSKPPE 1009
Score = 53.9 bits (128), Expect = 8e-07
Identities = 108/552 (19%), Positives = 206/552 (37%), Gaps = 69/552 (12%)
Query: 282 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 341
+P K E+EE KS + SP + P + ++P + E ++ +
Sbjct: 526 SPAEAKSPEKEE-AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKA 584
Query: 342 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 401
S A++E + E+ + A+ + +S ++ K E K EK +
Sbjct: 585 KSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK---AKSP 641
Query: 402 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 461
T E KS ++ + E+E ++ + A+S +AE + + +EA
Sbjct: 642 TKEEAKS-------PEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 462 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 521
+ E + S E S +++++ P K + V+ + + +
Sbjct: 695 KSPVKEEAKSPEKAKSP----------VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744
Query: 522 GSPSKTVTP---KAVPMLTPKPYSQPKN-SQDVLKTFKVDGKVSVNGETVHREEEKER-E 576
SP K +P K + + +P+ + K ++ F K V E E+ K +
Sbjct: 745 KSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLK 804
Query: 577 CPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPN 636
AP + K + + + P E+K + P +E A T KTE
Sbjct: 805 EDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVK--------EPPKKAEEEKAPATPKTEEK 856
Query: 637 SQEDKNDGGKSR--KGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQ 694
K + K K +E EP VE P +++ E +D+
Sbjct: 857 KDSKKEEAPKKEAPKPKVE-EKKEPA---------------VEKPKESKVEAKKEEAEDK 900
Query: 695 KK---PENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSP 751
KK PE E KVE+ ++ KPK A K P+ + P+ ++
Sbjct: 901 KKVPTPEKEAPAKVEV---KEDAKPKEKTEVAK-------KEPDDAKAKEPSKPAEKKEA 950
Query: 752 SSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVE 811
+ EK + K PEE+ + + K +++ + L +E + + +K ++ QK+ +
Sbjct: 951 APEKKDTKEEKAK----KPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSK 1006
Query: 812 EEERRYYEEERK 823
E+ ++ K
Sbjct: 1007 PPEKATEDKAAK 1018
Score = 46.6 bits (109), Expect = 1e-04
Identities = 88/454 (19%), Positives = 164/454 (36%), Gaps = 31/454 (6%)
Query: 214 QTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMS---ARRTSHGEPKSAVPFNQYL 270
+ SP+ + + S +E+ P + VK++ S A+ E KS
Sbjct: 577 EVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPE 636
Query: 271 PNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFD 330
KS +P + K E+EE KS A SP+ E ++PV +A+S
Sbjct: 637 KAKSPTKEEAKSPEKAKSPEKEE-AKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK 695
Query: 331 MRCEEEA--------AVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDL 382
+EEA V+ +++ ++ + + + + KS ++ S +
Sbjct: 696 SPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEK 755
Query: 383 IKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGI 442
K + + K A E+ S K + + V+E+ + + K E E
Sbjct: 756 AKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIP 815
Query: 443 LQQYIERFTISEAVLERL---EMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKF 499
++ ++ E + + E PK E + + D + ++++ P PK
Sbjct: 816 KKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEA-PKPKV 874
Query: 500 TATVETTIARASVLDTSMSAGSGSPSKTV-TP--KAVPMLTPKPYSQPKNSQDVLKTFKV 556
E + + K V TP +A + K ++PK +V K
Sbjct: 875 EEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPD 934
Query: 557 DGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINI 616
D K +E K E AP TK + + + + K+D+ ++
Sbjct: 935 DAKA--------KEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEP 986
Query: 617 KKPNSVPQELAATTE----KTEPNSQEDKNDGGK 646
KP + E +++T+ K + EDK GK
Sbjct: 987 SKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 35.8 bits (81), Expect = 0.23
Identities = 48/247 (19%), Positives = 98/247 (39%), Gaps = 27/247 (10%)
Query: 741 LPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLK 800
+P++++ + S EK V+ + E+ + Q E+ ++ +E ++E+ + K
Sbjct: 429 IPSVSTHIKVKSEEKIKVV---------EKSEKETVIVEEQTEETQVTEEVTEEEEKEAK 479
Query: 801 EEWEKAQKEVEEEERRYYEEERKI--IEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKI 858
EE K ++ EEEE EEE K E+ P + S + + S + +
Sbjct: 480 EEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAK-------- 531
Query: 859 DLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHED 918
EK++ + + + +E + + E A S V
Sbjct: 532 -----SPEKEEAKSPAEVKSPEK-AKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAK 585
Query: 919 HQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKT-LPLDKSINHQIESPSER 977
EA +P +P+ A+ P + ++ +P + VK + P + + +SP++
Sbjct: 586 SPAKEEAKSPAEAKSPEKAKSPVK-EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE 644
Query: 978 RKKSPRE 984
KSP +
Sbjct: 645 EAKSPEK 651
>gi|238908501 sciellin isoform 3 [Homo sapiens]
Length = 646
Score = 55.8 bits (133), Expect = 2e-07
Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Query: 980 KSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQC 1039
KSP++ +Q T S +RS+ + +C+ C PLG MI++ L + H C
Sbjct: 547 KSPKDGYQENISGKYIQTVYSTS-DRSVIERDMCTYCRKPLGVETKMILDELQICCHSTC 605
Query: 1040 FRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 1073
F+C ICK L + +G + I ++C CY +
Sbjct: 606 FKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 639
>gi|238908499 sciellin isoform 1 [Homo sapiens]
Length = 688
Score = 55.8 bits (133), Expect = 2e-07
Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Query: 980 KSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQC 1039
KSP++ +Q T S +RS+ + +C+ C PLG MI++ L + H C
Sbjct: 589 KSPKDGYQENISGKYIQTVYSTS-DRSVIERDMCTYCRKPLGVETKMILDELQICCHSTC 647
Query: 1040 FRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 1073
F+C ICK L + +G + I ++C CY +
Sbjct: 648 FKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 681
>gi|238908497 sciellin isoform 2 [Homo sapiens]
Length = 668
Score = 55.8 bits (133), Expect = 2e-07
Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Query: 980 KSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQC 1039
KSP++ +Q T S +RS+ + +C+ C PLG MI++ L + H C
Sbjct: 569 KSPKDGYQENISGKYIQTVYSTS-DRSVIERDMCTYCRKPLGVETKMILDELQICCHSTC 627
Query: 1040 FRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 1073
F+C ICK L + +G + I ++C CY +
Sbjct: 628 FKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 661
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 55.1 bits (131), Expect = 4e-07
Identities = 87/431 (20%), Positives = 170/431 (39%), Gaps = 57/431 (13%)
Query: 570 EEEKERECPTVAPAH-SLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAA 628
E +KE + PT+ A SL +M A + E K ++ I++ +V +
Sbjct: 116 ERQKEFD-PTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQK 174
Query: 629 TTEK-TEPNSQEDKN----DGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQ 683
+ E N +EDK + K ++G+I E T TV
Sbjct: 175 NDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVM-------S 227
Query: 684 LKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPN 743
LKN ++ K+ E G E+ +K+ + EA EA +
Sbjct: 228 LKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERA------RLEAEERE--R 279
Query: 744 LNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEW 803
+ ++ D +++ + + K A +ER R+E ++E+ R ++R +E+ ++KEE
Sbjct: 280 IKAEQDKKIADERARIEAEEKAAA----QERERREAEERERMREEEKRAAEERQRIKEEE 335
Query: 804 EKAQKE---VEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDL 860
++A +E ++EEE+R EE ++I E+ +A++ + + E + +
Sbjct: 336 KRAAEERQRIKEEEKRAAEERQRIKEE-------EKRAAEERQRARAEEEEKAKVEEQKR 388
Query: 861 GNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQ 920
+EK+ + +G+ ++E+K G V++ ++ +
Sbjct: 389 NKQLEEKKHAMQETKIKGE------------KVEQK---------IEGKWVNEKKAQEDK 427
Query: 921 LDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKK 980
L T Q + Q PT E++K + + DK +++S +R+K
Sbjct: 428 LQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKG 487
Query: 981 SPREHFQAGPF 991
Q G F
Sbjct: 488 FTEVKSQNGEF 498
Score = 50.1 bits (118), Expect = 1e-05
Identities = 65/279 (23%), Positives = 114/279 (40%), Gaps = 42/279 (15%)
Query: 570 EEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAAT 629
EEE RE A L + Q E + +V +E+N + NSVP E A T
Sbjct: 34 EEEAARERRRRARQERLRQKQEEESLGQV----------TDQVEVNAQ--NSVPDEEAKT 81
Query: 630 TEKTEPNSQEDKNDGG----------KSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFP 679
T N+Q + +D + R+ ++ A + F T+T S ++
Sbjct: 82 TTT---NTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLP----- 133
Query: 680 SSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFL---DKMPEA 736
S +++ND +E + +K E S + + + KS + DK E
Sbjct: 134 -SRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEE 192
Query: 737 NQLHLPNLNS----QVDSPSSEKSPVMTPQFKFWAWD----PEEERRRQEKWQQEQERLL 788
+ P S QV+ EK+ + + EE +++E+ +Q + +
Sbjct: 193 EEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEIS 252
Query: 789 QERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 827
+E+DK + E E+A+ E EE ER E+++KI ++
Sbjct: 253 HHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADE 291
Score = 46.2 bits (108), Expect = 2e-04
Identities = 122/613 (19%), Positives = 232/613 (37%), Gaps = 129/613 (21%)
Query: 231 SDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRK---- 286
+D+ LP R++ ++D + T+ E KS +Y + +T V +K
Sbjct: 126 TDASLSLPSRRM----QNDTAENETTEKEEKSESRQERY---EIEETETVTKSYQKNDWR 178
Query: 287 -----KKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 341
KK ++E+ + GE ++ E T + ++ + ++ +P
Sbjct: 179 DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEP 238
Query: 342 HSRARQEQL--QLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGE 399
+EQ ++ +++ EE+DK + + R +R + ++ IK E+++K +
Sbjct: 239 KQEEEREQGSDEISHHEKMEEEDKERAEAER--ARLEAEERERIKAEQDKKIAD------ 290
Query: 400 DGTSERRKSIKTYREIVQEKERRERELHEAYKNA--RSQEEAEGILQQYIERFTISEAVL 457
ER + + QE+ERRE E E + R+ EE + I ++ A
Sbjct: 291 ----ERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEE------KRAAE 340
Query: 458 ERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSM 517
ER + + E + E +Q + + A E ARA
Sbjct: 341 ERQRIKE--EEKRAAE----------------ERQRIKEEEKRAAEERQRARAE------ 376
Query: 518 SAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKEREC 577
+K K L K ++ + +K KV+ K+ G+ V+ ++ +E +
Sbjct: 377 ---EEEKAKVEEQKRNKQLEEKKHAMQETK---IKGEKVEQKIE--GKWVNEKKAQEDKL 428
Query: 578 PTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNS 637
T ++ K Q E +V +L++D KP +E+ K +
Sbjct: 429 QT-----AVLKKQGEEKGTKVQAKREKLQED---------KPTFKKEEIKDEKIKKDKEP 474
Query: 638 QEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKP 697
+E+ +KG E+ S + T + T S P + V ++ + P
Sbjct: 475 KEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTF------SRPGGRASVDTKEAEGAP 528
Query: 698 ENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSP 757
+ E ++E ++ + E E+ K EA
Sbjct: 529 QVEAGKRLE------ELRRRRGETESEEFEKLKQKQQEA--------------------- 561
Query: 758 VMTPQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQD-KLKEEWEKAQKEVEEEERR 816
A + EE ++++E+ ++ E Q R Q+E D KL+EE EK + + E E RR
Sbjct: 562 ---------ALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRR 612
Query: 817 --YYEEERKIIED 827
E+ +K+ ED
Sbjct: 613 AEAAEKRQKMPED 625
Score = 35.0 bits (79), Expect = 0.38
Identities = 43/206 (20%), Positives = 86/206 (41%), Gaps = 23/206 (11%)
Query: 769 DPEEERRRQEKWQQEQERLLQER--YQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIE 826
D E RR + ++E+ RL ER YQ+ D +E + ++ +E R +EE + +
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 827 DT-VVPFTVSSSSADQ---LSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGD--- 879
T V +S D+ +T+++ EG ++ ++E++ +R +++ +
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEF 121
Query: 880 -----DSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQL-DTEAGAPHCGTN 933
D+ L L +R + TE S+ E +++ +TE N
Sbjct: 122 DPTITDASLSLPSRRMQNDTAENETTE------KEEKSESRQERYEIEETETVTKSYQKN 175
Query: 934 PQLAQDPSQNQQTSNPTHSSEDVKPK 959
+D +N++ E+ KPK
Sbjct: 176 DW--RDAEENKKEDKEKEEEEEEKPK 199
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 54.7 bits (130), Expect = 5e-07
Identities = 98/512 (19%), Positives = 201/512 (39%), Gaps = 85/512 (16%)
Query: 332 RCEEEAAVQPHS-RARQEQLQLINNQLREEDDKWQDD---LARWKSRRRSVSQDLIKKEE 387
R EEE Q R ++E++ +LRE++ K ++ + R + R R ++L ++E+
Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK 297
Query: 388 ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE----RRERELHEAYKNARSQEEAEGIL 443
E ++ +KL E+ E+ + + E ++E+E R+E L E K R E+ + +
Sbjct: 298 ELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR--EQEQKMR 355
Query: 444 QQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATV 503
Q + E + E+ E + E+ E + K +R++
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE---------- 405
Query: 504 ETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVN 563
ET + + K + +P K + Q K + K ++ + K+
Sbjct: 406 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 465
Query: 564 GETVHRE-----EEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKK 618
E +E +EK RE + QM+E ++ ++ +
Sbjct: 466 EEMWGQEKKMWRQEKMRE----------QEDQMWEQEEKMRDQEQKMWDQEERM------ 509
Query: 619 PNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEF 678
E + E +E K + K E + E + T
Sbjct: 510 -----WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW-------------- 550
Query: 679 PSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQ 738
+ + EE+ ++ E +M + E++ Q+ K E E +KM E +
Sbjct: 551 ----DQEEKMREEERMREREKKMREEEEMMREQE---EKMQEQE--------EKMREQEE 595
Query: 739 LHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQERLLQERYQK---E 795
+ Q + ++ + + K W + E++ + QE+ EQE +QE+ +K +
Sbjct: 596 ----KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQ 651
Query: 796 QDKLKEEWEKAQKEVEE---EERRYYEEERKI 824
++K++E+ EK +++ E+ +E + E+E K+
Sbjct: 652 EEKMREQEEKMREQEEKMQGQEEKMREQEEKM 683
Score = 51.2 bits (121), Expect = 5e-06
Identities = 100/510 (19%), Positives = 205/510 (40%), Gaps = 74/510 (14%)
Query: 331 MRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERK 390
+R +EE + R R+++ ++RE+++K + R + R R ++L ++E+E +
Sbjct: 250 IRKQEEKMWRQEERLREQE-----GKMREQEEK----MRRQEKRLREQEKELREQEKELR 300
Query: 391 KMEKLLAGEDGTSERRKSIKTYREIVQEKE----RRERELHEAYKNARSQEEAEGILQQY 446
+ +KL E+ E+ + + E ++E+E R+E L E K R QE+ + Q
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK--MRDQE 358
Query: 447 IERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETT 506
+ E + E+ E + E+ E + K +R++ ET
Sbjct: 359 ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE----------ETM 408
Query: 507 IARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGET 566
+ + K + +P K + Q K + K ++ + K+ E
Sbjct: 409 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 468
Query: 567 VHRE-----EEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSI---EINIKK 618
+E +EK RE + QM+E ++ ++ + + +++
Sbjct: 469 WGQEKKMWRQEKMRE----------QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE 518
Query: 619 PNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEF 678
+E ++ E +E K + + + E E + E
Sbjct: 519 KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR-------------ER 565
Query: 679 PSSPQLKNDVSEEKDQKKPENE--MSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEA 736
+ + ++ E+++K E E M + E + Q + K E E + + +KM E
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ---EEKMQEQEEKM-WEQEEKMWE- 620
Query: 737 NQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQ 796
Q + Q + ++ + + K W + EE+ R QE+ +EQE E+ Q ++
Sbjct: 621 -QEEEDKMQEQEEMMWEQEEKMQEQEEKMW--EQEEKMREQEEKMREQE----EKMQGQE 673
Query: 797 DKLKEEWEKAQ----KEVEEEERRYYEEER 822
+K++E+ EK Q K E+EE+ +EE+
Sbjct: 674 EKMREQEEKMQGQEEKMREQEEKMRGQEEK 703
Score = 47.4 bits (111), Expect = 7e-05
Identities = 35/141 (24%), Positives = 68/141 (48%), Gaps = 18/141 (12%)
Query: 768 WDPEEERRRQEK--WQQE-----QERLLQERYQKEQDKLKEEWEKAQKEVEEEER----- 815
W+ EE+ R QE+ W+QE QE+ ++E+ QK +D+ + WE+ ++ E+EER
Sbjct: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379
Query: 816 RYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKS 875
+ +E+E K+ E+ + +M E M K + E++++ W++
Sbjct: 380 KMWEQEEKMQEEE----RIREREKKMREEEETMREQEEKMQKQE--ENMWEQEEKEWQQQ 433
Query: 876 FQGDDSDLLLKTRESDRLEEK 896
+ + L + + EEK
Sbjct: 434 RLPEQKEKLWEQEKMQEQEEK 454
Score = 46.2 bits (108), Expect = 2e-04
Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 34/158 (21%)
Query: 699 NEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNS---------QVD 749
NE K L +K+ +S + E L L + E + LP + + Q +
Sbjct: 182 NEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 241
Query: 750 SPSSEKSPVMTPQFKFWAWDP------------EEERRRQEKWQQEQERLL--QERYQKE 795
++ + + K W + EE+ RRQEK +EQE+ L QE+ +E
Sbjct: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301
Query: 796 QDKLKEE-----------WEKAQKEVEEEERRYYEEER 822
Q KL+E+ WE+ +K E+EE+ + +EER
Sbjct: 302 QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 339
Score = 43.5 bits (101), Expect = 0.001
Identities = 35/161 (21%), Positives = 73/161 (45%), Gaps = 19/161 (11%)
Query: 744 LNSQVDSPSSEKSPVMTPQFKFW-----AWDPEEERRRQEKWQQEQERLLQERYQKEQDK 798
+ Q D ++ + + K W W+ +E R +E+ +EQ+++ Q+ + ++K
Sbjct: 481 MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEK 540
Query: 799 LKEEWEKA---QKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTM 855
+E EK Q+E EE R E E+K+ E+ + +Q M E M
Sbjct: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ---EEKMREQEEKM 597
Query: 856 NKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEK 896
+ Q+EK + +K ++ ++ + + E D+++E+
Sbjct: 598 WE------QEEKMQEQEEKMWEQEEK--MWEQEEEDKMQEQ 630
Score = 43.1 bits (100), Expect = 0.001
Identities = 40/157 (25%), Positives = 70/157 (44%), Gaps = 7/157 (4%)
Query: 749 DSPSSEKSPVMTPQFKFWAWD---PEEER-RRQEKWQQEQERLLQERYQKEQDKLKEEWE 804
D EK M Q K W + EEER R +EK +E+E ++E+ +K Q + + WE
Sbjct: 365 DERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 424
Query: 805 KAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQ 864
Q+E E +++R E++ K+ E + +Q E G K+
Sbjct: 425 --QEEKEWQQQRLPEQKEKLWEQEKMQ-EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 481
Query: 865 DEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTE 901
E++D+ W++ + D + + +E E+ L E
Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE 518
Score = 38.9 bits (89), Expect = 0.027
Identities = 34/129 (26%), Positives = 61/129 (47%), Gaps = 11/129 (8%)
Query: 769 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRY-YEEERKIIED 827
+ EE R QE+ QEQE ++E+ +K ++ ++ E+ +K E+EE+ + EEE K+ E
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQ 630
Query: 828 TVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKT 887
+ + +Q M E M + Q+EK R ++ QG + + +
Sbjct: 631 EEMMWEQEEKMQEQ---EEKMWEQEEKMRE------QEEKM-REQEEKMQGQEEKMREQE 680
Query: 888 RESDRLEEK 896
+ EEK
Sbjct: 681 EKMQGQEEK 689
Score = 38.1 bits (87), Expect = 0.045
Identities = 24/130 (18%), Positives = 60/130 (46%)
Query: 690 EEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVD 749
EE+D+ + + EM + E + ++ K E + + + E Q + Q +
Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
Query: 750 SPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKE 809
++ + + K + + + ++ W QE++ QE ++++++++++ EK Q+
Sbjct: 682 KMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQER 741
Query: 810 VEEEERRYYE 819
+ E E R E
Sbjct: 742 LPEHEERCSE 751
Score = 37.4 bits (85), Expect = 0.077
Identities = 36/143 (25%), Positives = 65/143 (45%), Gaps = 20/143 (13%)
Query: 690 EEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVD 749
EEK QK+ EN + + Q++ + K E +K+ E + + Q +
Sbjct: 412 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE----KIRDQEE 467
Query: 750 SPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKE 809
EK K W +E+ R QE EQE ++++ QK D+ + WE+ ++
Sbjct: 468 MWGQEK--------KMWR---QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERL 516
Query: 810 VEEEER-----RYYEEERKIIED 827
E+EER + +++E K+ E+
Sbjct: 517 REKEERMREQKKMWQQEEKMREE 539
Score = 37.0 bits (84), Expect = 0.10
Identities = 95/529 (17%), Positives = 198/529 (37%), Gaps = 83/529 (15%)
Query: 340 QPHSRARQEQLQLINNQLREEDDKWQDDLAR-WKSRRRSVSQDLIKKEEERKKM------ 392
Q + QE++ +LRE++ K + + W+ R Q+ K E+ +KM
Sbjct: 226 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEG-KMREQEEKMRRQEKR 284
Query: 393 ----EKLLAGEDGTSERRKSIKTYREIVQEKE------------------RRERELHEAY 430
EK L ++ +K ++ E +QE+E R+E L E
Sbjct: 285 LREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344
Query: 431 KNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLR 490
K R QE+ + Q + E + E+ E + E+ E + K +R
Sbjct: 345 KQMREQEQK--MRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMR 402
Query: 491 QQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDV 550
++ ET + + K + +P K + Q K +
Sbjct: 403 EEE----------ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQE 452
Query: 551 LKTFKVDGKVSVNGETVHRE-----EEKERECPTVAPAHSLTKSQMFEGVARVHGSPLEL 605
K ++ + K+ E +E +EK RE + QM+E ++ ++
Sbjct: 453 EKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE----------QEDQMWEQEEKMRDQEQKM 502
Query: 606 KQDNGSI---EINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHF 662
+ + +++ +E ++ E +E K + + + E E +
Sbjct: 503 WDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM 562
Query: 663 TTTVTRCSPTVAFV-EFPSSPQLKNDVSEEKDQK--KPENEMSGKVELVLSQKVVKPKSP 719
+ + E Q + + E+++K + E +M + E + Q+ +
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622
Query: 720 EPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEK 779
E DKM E ++ + + E+ M Q + E+ R ++EK
Sbjct: 623 EE---------DKMQEQEEMMW-----EQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 668
Query: 780 WQQEQERL--LQERYQKEQDKLKEEWEKAQKEVE----EEERRYYEEER 822
Q ++E++ +E+ Q +++K++E+ EK + + E +EE+ + +EE+
Sbjct: 669 MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEK 717
Score = 36.2 bits (82), Expect = 0.17
Identities = 57/275 (20%), Positives = 113/275 (41%), Gaps = 39/275 (14%)
Query: 284 LRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHS 343
+R++K +E+ +K+W ER + ++ M+ +EE +
Sbjct: 536 MREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE 595
Query: 344 RA--RQEQLQLINNQL---------REEDDKWQD-DLARWKSRRRSVSQD--------LI 383
+ ++E++Q ++ +EE+DK Q+ + W+ + Q+ +
Sbjct: 596 KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM 655
Query: 384 KKEEE--RKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEG 441
+++EE R++ EK+ E+ E+ + ++ QE++ RE+E + R QEE
Sbjct: 656 REQEEKMREQEEKMQGQEEKMREQEEKMQG-----QEEKMREQE-----EKMRGQEEK-- 703
Query: 442 ILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTA 501
+ Q + + E + + EM + ER + + L P + + LPP K
Sbjct: 704 MWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERL--PEHEERCSEPCLPPSKVLC 761
Query: 502 TVETTIARASVLDTSMSAGSGSPSKTVTPKAVPML 536
+ T SV AG GSP T + + L
Sbjct: 762 NMSHT---GSVEPAGGEAGEGSPQDNPTAQEIMQL 793
Score = 30.8 bits (68), Expect = 7.2
Identities = 33/138 (23%), Positives = 67/138 (48%), Gaps = 23/138 (16%)
Query: 347 QEQLQLINN-----QLREEDDKWQDDLARW---KSRRRSVSQDLIKKEEE--------RK 390
QE+L+L + QL ++ K + + A++ + + ++ +++ ++EEE RK
Sbjct: 193 QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRK 252
Query: 391 KMEKLLAGEDGTSERRKSIKTYREIVQEKERR----ERELHEAYKNARSQE---EAEGIL 443
+ EK+ E+ E+ ++ E ++ +E+R E+EL E K R Q+ E E +
Sbjct: 253 QEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQM 312
Query: 444 QQYIERFTISEAVLERLE 461
Q+ E+ E + E
Sbjct: 313 QEQEEKMWEQEEKMREQE 330
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 54.7 bits (130), Expect = 5e-07
Identities = 122/602 (20%), Positives = 233/602 (38%), Gaps = 104/602 (17%)
Query: 344 RARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTS 403
+ R +L Q +E ++++A ++ + +S S +L ++ +E+ L+ D
Sbjct: 293 KCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLS--DIEE 350
Query: 404 ERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAV-LERLEM 462
+ +Y++ +Q+ E R ++ E L++Y + + A+ +E
Sbjct: 351 RHNHDLSSYQDTIQQLENELRG---------TKWEMARHLREYQDLLNVKMALDIEIAAY 401
Query: 463 PKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSG 522
K+LE E S+F Y + PP T+ + I + V
Sbjct: 402 RKLLE---GEETRFSTFAGSITGPLYTHR----PP---ITISSKIQKPKV---------E 442
Query: 523 SPSKTVTPKAVPMLTPKPYSQPKNSQ--DVLKTFKVDGKVSVNGETVHREEEKERECPTV 580
+P V K V + + + + S+ + L + VS+ E EEKE E
Sbjct: 443 APKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAE 502
Query: 581 APAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQED 640
+ KS V + E+K++ G E + ++ A +++ E
Sbjct: 503 EEEVAAKKSP-------VKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE------ 549
Query: 641 KNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPEN- 699
+GG ++G+ E E + E + + + + +E K++KK E
Sbjct: 550 --EGGSEKEGSSEKEEGEQE----------------EGETEAEAEGEEAEAKEEKKVEEK 591
Query: 700 --EMSGKVELVLSQKVVKP---KSPEPEATLTFPF---LDKMPEANQLHLPNLNSQVDSP 751
E++ K ELV KV KP KSP P++ + + K P + P S V+
Sbjct: 592 SEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 651
Query: 752 SSE---KSPVMTPQFKFWAWDPEEERRRQ-------EKWQQEQERLLQERYQKEQDKLKE 801
KSPV + P EE+ + E+ + + E E+ ++E+ ++KE
Sbjct: 652 GKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKE 711
Query: 802 EWEKAQKEVEEEERRYYEEERK----IIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNK 857
++ + E +EE+ + E++K + E+ V + S + EG +
Sbjct: 712 APKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQE 771
Query: 858 IDL------GNCQDEKQDRRWKKSFQGD-----------DSDLLLKTRESDRLEEKGSLT 900
+ G ++E D+ K S + D + + K + S R EEKG +T
Sbjct: 772 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVT 831
Query: 901 EG 902
G
Sbjct: 832 NG 833
Score = 45.8 bits (107), Expect = 2e-04
Identities = 78/362 (21%), Positives = 150/362 (41%), Gaps = 42/362 (11%)
Query: 319 VSDDAESTSMFDMRCEEEAAVQPHSR----ARQEQLQLINNQLREEDDKWQDDLARWKSR 374
V + E T + D + E E A+ + + +E+ + + EE + ++++A KS
Sbjct: 453 VEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSP 512
Query: 375 RRS----VSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAY 430
++ V ++ +KEEE + E+ E S++ + + +E EKE E+E E
Sbjct: 513 VKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE 572
Query: 431 KNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTE-PNLSSFLND------- 482
A EEAE ++ +E + A E L +E+ + P S + +
Sbjct: 573 AEAEG-EEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP 631
Query: 483 PNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYS 542
+P++ + +P ++ + ++ V + S S SP V KA + P
Sbjct: 632 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSP---VEEKAKSPVPKSPVE 688
Query: 543 QPKNSQDVLK-----TFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVAR 597
+ K+ +V K + + K + E V ++EEK ++ P A S K + V
Sbjct: 689 EAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVT 748
Query: 598 VHGSPLELKQDNGSIEINIKKPNS-----VPQELAATTEKTEPNSQEDKNDGGK--SRKG 650
+ S++++++K + QE E S+E+ +D G SRK
Sbjct: 749 I----------TKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKE 798
Query: 651 NI 652
+I
Sbjct: 799 DI 800
Score = 44.3 bits (103), Expect = 6e-04
Identities = 57/311 (18%), Positives = 126/311 (40%), Gaps = 49/311 (15%)
Query: 707 LVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFW 766
+ +S K+ KPK P+ + F++++ E ++V+ SE +T +
Sbjct: 430 ITISSKIQKPKVEAPKLKVQHKFVEEIIE---------ETKVEDEKSEMEEALTAITEEL 480
Query: 767 AWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIE 826
A +EE++ + ++E+ +E ++ +K + ++E E+E +EE + +
Sbjct: 481 AVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEED 540
Query: 827 DTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLK 886
+ + +DQ S EGS + E+++ + +G++++
Sbjct: 541 E--------GAKSDQAEEGGSEKEGSSEKE-------EGEQEEGETEAEAEGEEAE---- 581
Query: 887 TRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQT 946
+E ++EEK E+ D + P +P + + P + +
Sbjct: 582 AKEEKKVEEKSE-------------EVATKEELVADAKVEKPEKAKSP-VPKSPVEEKGK 627
Query: 947 SNPTHSSEDVK-----PKTLPLDKSINHQIESPSERRKKSP--REHFQAGPFSPCSPTPP 999
S S + K PK+ +K + +SP E + KSP + + SP +P
Sbjct: 628 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPV 687
Query: 1000 GQSPNRSISGK 1010
++ +++ GK
Sbjct: 688 EEAKSKAEVGK 698
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 52.4 bits (124), Expect = 2e-06
Identities = 101/481 (20%), Positives = 181/481 (37%), Gaps = 75/481 (15%)
Query: 385 KEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERR-----ERELHEAYKNARSQEEA 439
K +ER+++ K + ER K + + + EK++R E+++ E ++ Q +
Sbjct: 50 KSDERQRLAK-----ERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQR 104
Query: 440 EGILQQYIE--RFTISEAVLERLE--MPKILERSHSTEPNLSSFLNDP---NPMKYLRQQ 492
E + +E R ERLE M + LER+ E P P +
Sbjct: 105 EDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKYSWGAPLAIGPGGHDACD 164
Query: 493 SLPPPKFTATVETTIARASVLDTSMSAGSGSPSKT--VTPKAVPM--LTPKPYSQPKNSQ 548
L + T L +S A S SP + V P+ P+ L P S P +
Sbjct: 165 KLSTSTMSLPKPTEPPMNKRLSSSTVAISYSPDRVFHVCPRLAPLGPLNPSYKSSPTRNI 224
Query: 549 DVLKTFKVD-------GKVSVNG------ETVHREEEKERECPTVAPAHSLTKSQMFEGV 595
+ K GK +++G E V R + P V L + + G+
Sbjct: 225 EKKKATSTSTSGAGDVGKEALSGGEASLVEKVKRGQRTATSLPVVNFGSPLRRCEFSGGI 284
Query: 596 ARVHGSPLELKQDNGSIEINIK--KP----NSVPQELAATTEKTEPNSQEDKNDGGKSRK 649
+ SP+ K + + K KP + V L A + + P + +K K R+
Sbjct: 285 PKRPSSPVISKTATKAYPQSPKTTKPPYPGSPVKYRLPALSGQDMPKRKAEKEKSNKERE 344
Query: 650 GNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVL 709
G + ++ PQ L+ V ++ +K GK E
Sbjct: 345 GTLAQQAAGPQ-------------------GEEALEKHVVDKHASEKHAAAAGGKAEN-- 383
Query: 710 SQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWD 769
S + KP + +A L + + Q L + + E+ D
Sbjct: 384 SAALGKPTAGTTDAGEAAKILAE--KRRQARLQKEQEEQERVEKEEQ------------D 429
Query: 770 PEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTV 829
E + K ++E+ RL +E ++E+++ ++E EK ++E EE+ + E +RK E+ +
Sbjct: 430 RLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELL 489
Query: 830 V 830
+
Sbjct: 490 L 490
Score = 46.6 bits (109), Expect = 1e-04
Identities = 68/314 (21%), Positives = 127/314 (40%), Gaps = 41/314 (13%)
Query: 211 RSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYL 270
R ++T + V+ S R + +P R P +A + PK+ P
Sbjct: 258 RGQRTATSLPVVNFGSPLRRCEFSGGIPKR--PSSPVISKTATKAYPQSPKTTKPPYPGS 315
Query: 271 PNKSNQTAYVPAPLRKKKAEREEYRKSWS-----TATSPLGGERPFRYGPRTPVSDD--- 322
P K A + K+KAE+E+ K A P G E ++ S+
Sbjct: 316 PVKYRLPALSGQDMPKRKAEKEKSNKEREGTLAQQAAGPQGEEALEKHVVDKHASEKHAA 375
Query: 323 -----AESTSMFDMRCEE-----EAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWK 372
AE+++ EAA + RQ +LQ + + + QD L R +
Sbjct: 376 AAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREE 435
Query: 373 SRRRS------VSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQE---KERRE 423
+R++ + ++ K+EEERK+ E+ ++G +R+ + R+ +E KE++E
Sbjct: 436 LKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQE 495
Query: 424 RELHEAYKNARSQEEAEGILQQYIERFTIS-EAVLERLEMPKILERSHSTEPNLSSFLND 482
+E E + +E AE ++ E+ + E ++ ++E ++ + E
Sbjct: 496 QEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQERLERKKRIDE--------- 546
Query: 483 PNPMKYLRQQSLPP 496
MK R+ +PP
Sbjct: 547 --IMKRTRKSDVPP 558
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 50.1 bits (118), Expect = 1e-05
Identities = 111/571 (19%), Positives = 204/571 (35%), Gaps = 140/571 (24%)
Query: 285 RKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHS- 343
++++ +R ++ W G + R R P+ + E + R + E P
Sbjct: 758 QQEEEQRRDFTWQWQAEEKSERGRQ--RLSARPPLREQRERQLRAEERQQREQRFLPEEE 815
Query: 344 ---------RARQEQLQLINN-----------QLREEDDKWQDDLARWKSRRRSVSQDLI 383
R R+++LQ + QL+EE+D Q+D + RRRS Q
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQED----QERRRSQEQRRD 871
Query: 384 KK-----EEERKKMEKLLAGEDGTSER-RKSIKTYREIVQEKERRERELHEAYKNARSQE 437
+K EEERK+ L + E+ RK + +E +E +R ERE + R
Sbjct: 872 QKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYR 931
Query: 438 EAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPP 497
E E + Q+ + R E + + + L + P K RQ+
Sbjct: 932 EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGE-EPEKRRRQER--EK 988
Query: 498 KFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVD 557
K+ E +L + + + Q+ + ++
Sbjct: 989 KYREEEELQQEEEQLL-------------------------REEREKRRRQEWERQYRKK 1023
Query: 558 GKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIK 617
++ E + REE ++R + R + EL+Q+ + + +
Sbjct: 1024 DELQQEEEQLLREEREKRR---------------LQERERQYREEEELQQEEEQL-LGEE 1067
Query: 618 KPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVE 677
+ QEL K E QE++ +L EP+
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEE-----------QLLREEPE----------------- 1099
Query: 678 FPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEAN 737
K E + Q + E E+ + E +L ++ K + E E + E
Sbjct: 1100 -------KRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER--------QYREEE 1144
Query: 738 QLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQD 797
++ + P + + Q++ EEE + QQE+E+LL+E EQ+
Sbjct: 1145 EVQQEEEQLLREEPEKRRRQELERQYR------EEE-----ELQQEEEQLLRE----EQE 1189
Query: 798 KLKEEWEKAQKEVEEEER-----RYYEEERK 823
K ++E E+ +E EE +R RY +E+++
Sbjct: 1190 KRRQERERQYREEEELQRQKRKQRYRDEDQR 1220
Score = 48.9 bits (115), Expect = 3e-05
Identities = 128/636 (20%), Positives = 221/636 (34%), Gaps = 106/636 (16%)
Query: 288 KAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQ 347
K E EE R+ L E+ R R ++ E R E ++ R+
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEER---LQQRLRSEQQLRREQEERR 546
Query: 348 EQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERK----------KMEKLLA 397
EQL + R E ++ + L R + RR L+K+EEER+ ++E+ L
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRD---QLLKREEERRQQRLKREQEERLEQRLK 603
Query: 398 GEDGT---SERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISE 454
E+ E R+ + RE E+ERR++ L + R Q++ Q+ E+ E
Sbjct: 604 REEVERLEQEERREQRLKRE-EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Query: 455 AVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLD 514
ERLE + L+R H E + R +S P AR S
Sbjct: 663 EEEERLE--QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQS--- 717
Query: 515 TSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKE 574
K YS+P+ + + + + K R E E
Sbjct: 718 ------------------------KVYSRPRKQEGQRRRQEQEEK--------RRRRESE 745
Query: 575 RECPTVAPAHSLTKSQMFEGVAR--VHGSPLELKQDNGSIEINIKKPNSVPQELAATTEK 632
+ AH + Q E R E K + G ++ + P +E E+
Sbjct: 746 LQWQEEERAH---RQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEE 802
Query: 633 TE-------PNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLK 685
+ P +E + + R+ EL E + E +
Sbjct: 803 RQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE----------------EQLQRRERA 846
Query: 686 NDVSEEKDQKKPENEMSGKVELVLSQK----VVKPKSPEPEATLTFPFLDKMPEANQLHL 741
+ EE+D + + E E QK + + + P L + Q L
Sbjct: 847 QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLL 906
Query: 742 PNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQERLLQER-YQKEQDKLK 800
++ EK + ++ + ++ Q ++ ++R QER Q +DK
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
Query: 801 EEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDL 860
++ E+ E E+RR E E+K E+ + +QL + +
Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEEL-----QQEEEQL-----------LREEREK 1010
Query: 861 GNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEK 896
Q+ ++ R K Q ++ LL + RE RL+E+
Sbjct: 1011 RRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
Score = 42.4 bits (98), Expect = 0.002
Identities = 35/132 (26%), Positives = 60/132 (45%), Gaps = 3/132 (2%)
Query: 334 EEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKME 393
EEE Q H + R+EQ + R + K +++ R + RR ++EE R++
Sbjct: 430 EEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWL 489
Query: 394 KLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTIS 453
KL E + R+ + RE ++ERRE+ L + R Q+ Q E+
Sbjct: 490 KLEEEERREQQERREQQLRRE---QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERR 546
Query: 454 EAVLERLEMPKI 465
E +L+R E ++
Sbjct: 547 EQLLKREEEKRL 558
Score = 42.4 bits (98), Expect = 0.002
Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 10/132 (7%)
Query: 771 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVV 830
E E+RR+++W++ Q R E Q+E+ L+EE EK + ++E ER+Y EEE E+ +
Sbjct: 1007 EREKRRRQEWER-QYRKKDELQQEEEQLLREEREK--RRLQERERQYREEEELQQEEEQL 1063
Query: 831 PFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDR-------RWKKSFQGDDSDL 883
+ Q E + L + EK+ R R ++ Q ++ L
Sbjct: 1064 LGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL 1123
Query: 884 LLKTRESDRLEE 895
L + RE R +E
Sbjct: 1124 LREEREKRRRQE 1135
Score = 42.0 bits (97), Expect = 0.003
Identities = 41/164 (25%), Positives = 73/164 (44%), Gaps = 19/164 (11%)
Query: 285 RKKKAEREEYRKSWSTATS-------PLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEA 337
R+ + +EE K W + L E P R + ++R E +
Sbjct: 233 RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQE 292
Query: 338 AVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDL----IKKEEERKKME 393
Q R R+EQ QL Q EE+ + Q + R + RR ++ +++E+E ++ +
Sbjct: 293 EEQQQQRLRREQ-QLRRKQ--EEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
Query: 394 KLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQE 437
+L ++ E R+ + RE QE+ERRE++L + R Q+
Sbjct: 350 QLRREQE---EERREQQLRRE--QEEERREQQLRREQQLRREQQ 388
Score = 41.6 bits (96), Expect = 0.004
Identities = 122/623 (19%), Positives = 231/623 (37%), Gaps = 110/623 (17%)
Query: 332 RCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARW------------KSRRRSVS 379
R +E + RA +EQLQ EE ++ L R K ++R
Sbjct: 175 RQRQEWQEREERRAEEEQLQSCKGHETEEFPD-EEQLRRRELLELRRKGREEKQQQRRER 233
Query: 380 QDLIKKEEERK---KMEKLLAGEDGTSERRKSIKTYREIVQEKER-RERELHEAYKNARS 435
QD + +EEE K K E +L E+ + + + RE+ +E+E+ R+ E E + +
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP-QRQRELQEEEEQLRKLERQELRRERQE 292
Query: 436 QEEAEGIL--QQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQS 493
+E+ + L +Q + R E ++ E + ER E L + R+Q
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEER--REQQ 350
Query: 494 LPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKT 553
L + E + R + + Q + Q + +
Sbjct: 351 LRREQEEERREQQLRREQEEE------------------------RREQQLRREQQLRRE 386
Query: 554 FKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIE 613
++ + + E R E++ R + L + Q E K + E
Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH--EQKHEQERRE 444
Query: 614 INIKKPNSVPQELAATTEKTEPNSQED-----KNDGGKSRKGN-IELASSEPQHFTTTVT 667
+K+ ++ E+TE + QE K D + R+ ++L E +
Sbjct: 445 QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERRE------ 498
Query: 668 RCSPTVAFVEFPSSPQLKNDVSEEKDQ--KKPENEMSGKVELVLSQKVVKPKSPEPEATL 725
+ QL+ + E ++Q K+ E E + L Q++ + + E L
Sbjct: 499 --------QQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550
Query: 726 TFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQE 785
K E +L ++ E+ + + EE RRQ++ ++EQE
Sbjct: 551 ------KREEEKRLEQERREQRLKREQEERRDQLLKR---------EEERRQQRLKREQE 595
Query: 786 RLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTS 845
L++R ++E+ + E+ E+ ++ ++ EE EEER+ QL S
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEP---EEERR----------------QQLLKS 636
Query: 846 SSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALA 905
E + L Q E++++R K+ + + + LK RE + + L E
Sbjct: 637 EEQEE----RRQQQLRREQQERREQRLKREEEEERLEQRLK-REHEEERREQELAEEEQE 691
Query: 906 HSGNPVSKGVHE-DHQLDTEAGA 927
+ + + + QL++EA A
Sbjct: 692 QARERIKSRIPKWQWQLESEADA 714
Score = 41.2 bits (95), Expect = 0.005
Identities = 109/529 (20%), Positives = 204/529 (38%), Gaps = 83/529 (15%)
Query: 334 EEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLA-----RWKSRRRSVSQDLIKKEEE 388
E+ +P R RQE+ + REE++ Q++ R K RR+ + KK+E
Sbjct: 971 EQLLGEEPEKRRRQER----EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
Query: 389 RKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQ--EEAEGILQQY 446
+++ E+LL E E+R+ +QE+ER+ RE E + EE E +Q
Sbjct: 1027 QQEEEQLLREE---REKRR--------LQERERQYREEEELQQEEEQLLGEERETRRRQE 1075
Query: 447 IERFTISEAVLERLEMPKILERSHSTE-PNLSSFLNDPNPMKYLRQQSLPPPKFTATVET 505
+ER E L++ E + E + ++ +Q L E
Sbjct: 1076 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE-------ER 1128
Query: 506 TIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGE 565
R L+ + V + +L +P + + Q++ + ++ + ++ E
Sbjct: 1129 EKRRRQELERQYRE-----EEEVQQEEEQLLREEP--EKRRRQELERQYREEEELQQEEE 1181
Query: 566 TVHREE------EKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKP 619
+ REE E+ER+ + Q + R +LK + N +
Sbjct: 1182 QLLREEQEKRRQERERQYREEEELQRQKRKQRY----RDEDQRSDLKWQWEPEKENAVRD 1237
Query: 620 NSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFP 679
N V E + ED + + +++ E Q R FP
Sbjct: 1238 NKV---YCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFP 1294
Query: 680 SSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQL 739
QL+ + E+K+ K+ + + + +L+ ++ K + E + K E QL
Sbjct: 1295 EEEQLERE--EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR--------KFREEEQL 1344
Query: 740 -----HLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEK------------WQQ 782
P + D E+ Q + + + E+ RRQE+ Q+
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFL-EEEQRLRRQERERKFLKEEQQLRCQE 1403
Query: 783 EQERLLQERYQK----EQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 827
+++L Q+R +K EQ ++E ++ +E E++ RR E ERK +E+
Sbjct: 1404 REQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ-ERERKFLEE 1451
Score = 40.8 bits (94), Expect = 0.007
Identities = 23/54 (42%), Positives = 37/54 (68%), Gaps = 4/54 (7%)
Query: 771 EEERRRQEKWQQEQERLLQERYQK--EQDKLKEEWEKAQKEVEEEERRYYEEER 822
EEE+ RQE Q++ R QERY+K E+++L+ E E+ Q +E +R++ EEE+
Sbjct: 1727 EEEQLRQETEQEQLRR--QERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Score = 40.0 bits (92), Expect = 0.012
Identities = 56/252 (22%), Positives = 107/252 (42%), Gaps = 22/252 (8%)
Query: 234 ESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREE 293
E L + ++++++ RR E + + L + Q R+++ +
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQERQYRE--EEQLQQEEEQLLREEREKRRRQERERQ 959
Query: 294 YRKS--WSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQ 351
YRK L GE P + R + + +++ EEE ++ R+ Q
Sbjct: 960 YRKDKKLQQKEEQLLGEEPEK---RRRQEREKKYREEEELQQEEEQLLREEREKRRRQEW 1016
Query: 352 LINNQLREEDDKWQDD---LARWKSRRRSVSQDL-IKKEEERKKMEKLLAGEDGTSERRK 407
Q R++D+ Q++ L + +RR ++ ++EEE ++ E+ L GE+ + RR+
Sbjct: 1017 --ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQ 1074
Query: 408 SI-KTYREIVQEKERRERELHEAYKNARSQE-----EAEGILQQYIERFTISEAVLERLE 461
+ + YR+ + ++ E+ L E + R QE E LQQ E+ E R +
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ 1134
Query: 462 MPKILERSHSTE 473
LER + E
Sbjct: 1135 E---LERQYREE 1143
Score = 39.3 bits (90), Expect = 0.020
Identities = 31/148 (20%), Positives = 68/148 (45%), Gaps = 4/148 (2%)
Query: 771 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRY-YEEERKIIEDTV 829
EEE+ RQE+ +Q+ +R +E+++L++E E+ Q ++ + +Y +EEE+ +E+
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834
Query: 830 VPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRE 889
+ + E S + + Q+E+Q RR ++ + + + + +E
Sbjct: 1835 QRLRQERDRQYRAEEQFATQEKS---RREEQELWQEEEQKRRQERERKLREEHIRRQQKE 1891
Query: 890 SDRLEEKGSLTEGALAHSGNPVSKGVHE 917
R + G + G + G H+
Sbjct: 1892 EQRHRQVGEIKSQEGKGHGRLLEPGTHQ 1919
Score = 38.1 bits (87), Expect = 0.045
Identities = 33/131 (25%), Positives = 60/131 (45%), Gaps = 8/131 (6%)
Query: 769 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDT 828
+ E+RRRQE +Q +E +E Q+E+ L+EE EK ++ +E ER+Y EEE E+
Sbjct: 1126 EEREKRRRQELERQYREE--EEVQQEEEQLLREEPEKRRR--QELERQYREEEELQQEEE 1181
Query: 829 VVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRW----KKSFQGDDSDLL 884
+ + E + +D++ D +W +K D+ +
Sbjct: 1182 QLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVY 1241
Query: 885 LKTRESDRLEE 895
K RE+++ +
Sbjct: 1242 CKGRENEQFRQ 1252
Score = 38.1 bits (87), Expect = 0.045
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 4/128 (3%)
Query: 769 DPEEERRRQEKWQQEQERLLQERYQK----EQDKLKEEWEKAQKEVEEEERRYYEEERKI 824
+ +E +RR K Q+E++ L +ER +K E D+ E E+ +E EE+ R E +RK
Sbjct: 1303 EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKF 1362
Query: 825 IEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLL 884
E+ + ++ + + CQ+ +Q R + + + +
Sbjct: 1363 REEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQ 1422
Query: 885 LKTRESDR 892
L +E DR
Sbjct: 1423 LSRQERDR 1430
Score = 38.1 bits (87), Expect = 0.045
Identities = 21/66 (31%), Positives = 41/66 (62%), Gaps = 11/66 (16%)
Query: 771 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRY---------YEEE 821
E++ RRQE+ QQ ++ ++R +E+++L++E E+ Q +E +R++ E+E
Sbjct: 1537 EQQLRRQERGQQRRQD--RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594
Query: 822 RKIIED 827
RK +ED
Sbjct: 1595 RKFMED 1600
Score = 37.7 bits (86), Expect = 0.059
Identities = 37/148 (25%), Positives = 66/148 (44%), Gaps = 14/148 (9%)
Query: 330 DMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEER 389
+ + E ++ + R+EQ QLR E ++ + + + RR Q L +++EER
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE---QRLKREQEER 454
Query: 390 KKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQE---------EAE 440
+ K + + R+ + R+ QE+ERRER L + R Q+ E E
Sbjct: 455 RDWLKREEETERHEQERRKQQLKRD--QEEERRERWLKLEEEERREQQERREQQLRREQE 512
Query: 441 GILQQYIERFTISEAVLERLEMPKILER 468
+Q ++R E + +RL + L R
Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRR 540
Score = 37.7 bits (86), Expect = 0.059
Identities = 71/320 (22%), Positives = 130/320 (40%), Gaps = 39/320 (12%)
Query: 151 KEFEGLLAQMRKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPR---HGRD-DSFDSLD 206
+E E L Q RK E + ++ W+ E+ +++ + GR+ + F L+
Sbjct: 1200 REEEELQRQKRKQRYRDEDQRSDLKWQ-----WEPEKENAVRDNKVYCKGRENEQFRQLE 1254
Query: 207 SFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPF 266
R RQ+ L G R + E R+ + + E K A
Sbjct: 1255 DSQLRDRQSQQDLQHLLGEQQERDREQE----RRRWQQRDRHFPEEEQLEREEQKEA--- 1307
Query: 267 NQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGG--ERPFRYGPRTPVSDDAE 324
+ KS + + R++K R+E + + L E+P R R + E
Sbjct: 1308 -KRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEE 1366
Query: 325 STSMFDMR--CEEEAAVQPHSRARQ---EQLQLI----NNQLREEDDKW----QDDLARW 371
R EEE ++ R R+ E+ QL QLR++ D+ + L+R
Sbjct: 1367 LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQ 1426
Query: 372 KSRR--RSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEA 429
+ R R Q + ++E ERK +E+ + ER + + +++QE+E E++LH
Sbjct: 1427 ERDRKFREEEQQVRRQERERKFLEE---EQQLRQERHRKFREEEQLLQERE--EQQLHRQ 1481
Query: 430 YKNARSQEEAEGILQQYIER 449
++ + EE + + +Q +R
Sbjct: 1482 ERDRKFLEEEQQLRRQERDR 1501
Score = 37.7 bits (86), Expect = 0.059
Identities = 21/59 (35%), Positives = 38/59 (64%), Gaps = 1/59 (1%)
Query: 769 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 827
+ E++ RRQE+ ++ + Q R Q+ + K +EE E+ ++E E+E+ R E RKI+E+
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREE-EQLRQETEQEQLRRQERYRKILEE 1752
Score = 37.4 bits (85), Expect = 0.077
Identities = 42/208 (20%), Positives = 83/208 (39%), Gaps = 17/208 (8%)
Query: 285 RKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSR 344
R++ EREE R S G E P + + ++R + Q R
Sbjct: 177 RQEWQEREERRAEEEQLQSCKGHETE-----EFPDEEQLRRRELLELRRKGREEKQQQRR 231
Query: 345 ARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSE 404
RQ+++ +EE++K W+ R + ++ K +EE + ++ L E+
Sbjct: 232 ERQDRV------FQEEEEK------EWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLR 279
Query: 405 RRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPK 464
+ + + RE +E+++++R E + +EE ++ E+ E ER E
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQL 339
Query: 465 ILERSHSTEPNLSSFLNDPNPMKYLRQQ 492
E+ E L + + LR++
Sbjct: 340 RREQEERREQQLRREQEEERREQQLRRE 367
Score = 37.0 bits (84), Expect = 0.10
Identities = 22/64 (34%), Positives = 41/64 (64%), Gaps = 7/64 (10%)
Query: 771 EEERRRQEKWQQ--EQERLLQERYQK-----EQDKLKEEWEKAQKEVEEEERRYYEEERK 823
+E+ RRQE++++ E+E+L ER ++ E+D+ E E+ ++E EE++ R E +RK
Sbjct: 1737 QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRK 1796
Query: 824 IIED 827
E+
Sbjct: 1797 FREE 1800
Score = 36.2 bits (82), Expect = 0.17
Identities = 29/117 (24%), Positives = 59/117 (50%), Gaps = 10/117 (8%)
Query: 330 DMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVS--QDLIKKEE 387
D + EE + +Q + Q + + REE+ + L R + R+ + Q L ++E
Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQ----LRRQERERKFLQEEQQLRRQEL 1721
Query: 388 ERKKMEKLLAGEDGTSERRKSIKTYREIVQEK----ERRERELHEAYKNARSQEEAE 440
ERK E+ ++ E+ + + YR+I++E+ ER E++L ++ + +EE +
Sbjct: 1722 ERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Score = 35.4 bits (80), Expect = 0.29
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 9/58 (15%)
Query: 773 ERRRQEKWQQEQERLLQERYQKEQDKL---------KEEWEKAQKEVEEEERRYYEEE 821
+RRRQ++ +QE+E E ++Q++L +E W + Q+ E EERR EE+
Sbjct: 135 QRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQ 192
Score = 35.4 bits (80), Expect = 0.29
Identities = 31/152 (20%), Positives = 71/152 (46%), Gaps = 13/152 (8%)
Query: 287 KKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRAR 346
+K ER+E R+ ++ R + + E + R E++ + R
Sbjct: 279 RKLERQELRRERQEEEQQ---QQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR 335
Query: 347 QEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERR 406
++QL+ RE++++ + L R + R Q +++E+E ++ E+ L E R
Sbjct: 336 EQQLR------REQEERREQQLRREQEEERREQQ--LRREQEEERREQQLRREQ-QLRRE 386
Query: 407 KSIKTYREIVQEKE-RRERELHEAYKNARSQE 437
+ ++ +++ +E++ RRE++L + R Q+
Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Score = 35.4 bits (80), Expect = 0.29
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 10/102 (9%)
Query: 733 MPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQER------ 786
+ E QL Q+ K Q D + Q+ +QE+ER
Sbjct: 1393 LKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452
Query: 787 --LLQERYQK--EQDKLKEEWEKAQKEVEEEERRYYEEERKI 824
L QER++K E+++L +E E+ Q +E +R++ EEE+++
Sbjct: 1453 QQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQL 1494
Score = 35.4 bits (80), Expect = 0.29
Identities = 20/62 (32%), Positives = 40/62 (64%), Gaps = 8/62 (12%)
Query: 769 DPEEERRRQE---KWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKII 825
+ E++ RRQE K+ +E+++L QER++K +++ E+ +E EE++ E +RK +
Sbjct: 1434 EEEQQVRRQERERKFLEEEQQLRQERHRKFREE-----EQLLQEREEQQLHRQERDRKFL 1488
Query: 826 ED 827
E+
Sbjct: 1489 EE 1490
Score = 35.4 bits (80), Expect = 0.29
Identities = 21/57 (36%), Positives = 36/57 (63%), Gaps = 4/57 (7%)
Query: 769 DPEEERRRQEKWQQ-EQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKI 824
+ E++ RRQE QQ QER +R +E ++L +E E+ Q +E +R++ EEE ++
Sbjct: 1599 EDEQQLRRQEGQQQLRQER---DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQL 1652
Score = 35.0 bits (79), Expect = 0.38
Identities = 18/57 (31%), Positives = 35/57 (61%)
Query: 771 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 827
E+ER+ E QQ + + Q++ ++E+D+ E E+ +E EE++ E +RK +E+
Sbjct: 1592 EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEE 1648
Score = 34.3 bits (77), Expect = 0.65
Identities = 34/126 (26%), Positives = 66/126 (52%), Gaps = 11/126 (8%)
Query: 334 EEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRR------RSVSQDLIKKEE 387
+EE ++ R +Q + Q + + REE+ Q+ + SR+ R Q + ++E+
Sbjct: 1535 QEEQQLRRQERGQQRR-QDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 388 ERKKM--EKLLAGEDGTSE-RRKSIKTYREIVQ-EKERRERELHEAYKNARSQEEAEGIL 443
ERK M E+ L ++G + R++ + +RE Q +ER E++LH ++ + EE +
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653
Query: 444 QQYIER 449
+Q E+
Sbjct: 1654 RQEREQ 1659
Score = 34.3 bits (77), Expect = 0.65
Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 13/123 (10%)
Query: 324 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDD---KWQDDLARWKSRRRSVSQ 380
E + R E++ Q R +E+ QL Q REE + +D RW+ + + +
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQL--RQEREEQQLRPQQRDGKYRWEEEQLQLEE 1832
Query: 381 DLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKER-----RERELHEAYKNARS 435
+ +ER + + E+ + + KS + +E+ QE+E+ RER+L E + +
Sbjct: 1833 QEQRLRQERDRQYR---AEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQ 1889
Query: 436 QEE 438
+EE
Sbjct: 1890 KEE 1892
Score = 34.3 bits (77), Expect = 0.65
Identities = 20/64 (31%), Positives = 39/64 (60%), Gaps = 12/64 (18%)
Query: 769 DPEEERRRQEK---WQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKII 825
+ +E+R RQE+ ++ E++ QE+ ++E+ +L W+ EEE++R E ERK+
Sbjct: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRREEQEL---WQ------EEEQKRRQERERKLR 1881
Query: 826 EDTV 829
E+ +
Sbjct: 1882 EEHI 1885
Score = 34.3 bits (77), Expect = 0.65
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 4/54 (7%)
Query: 766 WAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYE 819
+A + R QE WQ+E+ Q+R Q+ + KL+EE + Q++ E+ R+ E
Sbjct: 1851 FATQEKSRREEQELWQEEE----QKRRQERERKLREEHIRRQQKEEQRHRQVGE 1900
Score = 33.9 bits (76), Expect = 0.86
Identities = 29/125 (23%), Positives = 60/125 (48%), Gaps = 5/125 (4%)
Query: 346 RQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSER 405
++ + Q ++ Q R+ ++ R + R + + D +K E +++ L GE+ R
Sbjct: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQL--LQEGEEQQLRR 1686
Query: 406 RKSIKTYREIVQEKERRERE---LHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEM 462
++ + +RE Q+ R+ERE L E + R + E + ++ + + T E + +
Sbjct: 1687 QERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERY 1746
Query: 463 PKILE 467
KILE
Sbjct: 1747 RKILE 1751
Score = 33.5 bits (75), Expect = 1.1
Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 8/62 (12%)
Query: 771 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQ--------KEVEEEERRYYEEER 822
EEE+ R E+ +Q+ R ++R +E+++L++E E+ Q K EEE+ R EE+
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ 1810
Query: 823 KI 824
++
Sbjct: 1811 QL 1812
Score = 33.1 bits (74), Expect = 1.5
Identities = 24/74 (32%), Positives = 46/74 (62%), Gaps = 20/74 (27%)
Query: 771 EEERRRQEKWQQ--EQERLLQER-----YQKEQDK--LKEEWEKAQKE-----------V 810
EE++ RQE+ ++ E+E+LLQER +++E+D+ L+EE + ++E
Sbjct: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS 1510
Query: 811 EEEERRYYEEERKI 824
+E ER++ EEE+++
Sbjct: 1511 QEPERKFLEEEQQL 1524
Score = 33.1 bits (74), Expect = 1.5
Identities = 33/142 (23%), Positives = 63/142 (44%), Gaps = 21/142 (14%)
Query: 761 PQFKFWAWDPEEERR-RQEKWQQEQERLL-----QERYQKEQDKLKEEWEKAQKEVEEEE 814
P+ KF + + R+ RQ K+ QE+++L Q+R Q K +EE E+ ++E EE++
Sbjct: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE-EQLRQEREEQQ 1571
Query: 815 RRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKK 874
E +RK F + + E + + Q+ +Q R ++
Sbjct: 1572 LSRQERDRK--------FRLEEQKVRRQEQERKFMEDEQQLRR------QEGQQQLRQER 1617
Query: 875 SFQGDDSDLLLKTRESDRLEEK 896
+ + + LL+ RE +L +
Sbjct: 1618 DRKFREDEQLLQEREEQQLHRQ 1639
Score = 33.1 bits (74), Expect = 1.5
Identities = 28/114 (24%), Positives = 53/114 (46%), Gaps = 6/114 (5%)
Query: 335 EEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEK 394
EE + R R+ +L+ + +E++ K+ +D + RR Q +++E +RK E
Sbjct: 1568 EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDE---QQLRRQEGQQQLRQERDRKFRED 1624
Query: 395 ---LLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ 445
L E+ R++ + + E + R+ERE + R E E +LQ+
Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE 1678
Score = 32.7 bits (73), Expect = 1.9
Identities = 36/155 (23%), Positives = 66/155 (42%), Gaps = 7/155 (4%)
Query: 285 RKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSR 344
R+++ RE+ + ER + R + E + + E ++ +
Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQ 394
Query: 345 ARQEQLQLINNQLREEDD-KWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTS 403
R+EQ QLR E + + L R + RR ++ +++ E+++ E+ L E
Sbjct: 395 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ--E 452
Query: 404 ERRKSIKTYREIVQEKERRERELHEAYKNARSQEE 438
ERR +K RE +E ER E+E + +EE
Sbjct: 453 ERRDWLK--RE--EETERHEQERRKQQLKRDQEEE 483
Score = 32.7 bits (73), Expect = 1.9
Identities = 32/145 (22%), Positives = 65/145 (44%), Gaps = 14/145 (9%)
Query: 334 EEEAAVQPHSRARQEQLQLINNQ------LREEDDKWQDD---LARWKSRRRSVSQDLIK 384
EE+ Q R +E+ QL+ + +E D K+ ++ L R + R+ Q+L
Sbjct: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS 1510
Query: 385 KEEERKKMEKLLAGEDGTSERR-----KSIKTYREIVQEKERRERELHEAYKNARSQEEA 439
+E ERK +E+ +R+ + ++ Q ++ R+R+ E + + +EE
Sbjct: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQ 1570
Query: 440 EGILQQYIERFTISEAVLERLEMPK 464
+ Q+ +F + E + R E +
Sbjct: 1571 QLSRQERDRKFRLEEQKVRRQEQER 1595
Score = 32.0 bits (71), Expect = 3.2
Identities = 18/58 (31%), Positives = 36/58 (62%), Gaps = 3/58 (5%)
Query: 771 EEERRRQEKWQQEQERLLQER-YQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 827
EEE+ QE+ +Q+ R ++R + +E+ +L+ ++ ++ E+E R E ERK +E+
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQLRR--QERDRKFREQELRSQEPERKFLEE 1520
Score = 32.0 bits (71), Expect = 3.2
Identities = 44/189 (23%), Positives = 74/189 (39%), Gaps = 23/189 (12%)
Query: 771 EEERRRQEKWQQEQERLLQERYQK----EQDKLKEEWEKAQKEVEEEERRY-------YE 819
EEE+ RQE+ +Q+ R QER +K EQ ++E E+ E E++ RR E
Sbjct: 1559 EEEQLRQEREEQQLSR--QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQE 1616
Query: 820 EERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQ-- 877
+RK ED + + E + + + +DR++++ Q
Sbjct: 1617 RDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLL 1676
Query: 878 --GDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQ 935
G++ L + R+ EE+ L K + E+ QL + Q
Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERER------KFLQEEQQLRRQELERKFREEEQ 1730
Query: 936 LAQDPSQNQ 944
L Q+ Q Q
Sbjct: 1731 LRQETEQEQ 1739
Score = 31.6 bits (70), Expect = 4.2
Identities = 31/155 (20%), Positives = 63/155 (40%), Gaps = 29/155 (18%)
Query: 771 EEERRRQEKWQQEQERLLQERYQKEQDKLK-------EEW-------------------- 803
+ +RR +E W+Q QE +E + E+++L+ EE+
Sbjct: 165 DRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE 224
Query: 804 EKAQKEVEEEERRYYEEERK--IIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLG 861
EK Q+ E ++R + EEE K +TV+ ++ + E + K++
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ 284
Query: 862 NCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEK 896
+ E+Q+ ++ + L K E R +++
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Score = 31.2 bits (69), Expect = 5.5
Identities = 23/117 (19%), Positives = 51/117 (43%), Gaps = 5/117 (4%)
Query: 334 EEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEE----- 388
E++ + Q R +E+ Q + Q RE ++ R + R+ ++ + +E E
Sbjct: 1420 EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLH 1479
Query: 389 RKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ 445
R++ ++ E+ R++ + +RE + ER+ E + Q+ LQ+
Sbjct: 1480 RQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQE 1536
Score = 30.8 bits (68), Expect = 7.2
Identities = 35/150 (23%), Positives = 67/150 (44%), Gaps = 27/150 (18%)
Query: 769 DPEEERRRQEKWQQ----------EQERLLQE------RYQKEQDKLKEEWEKAQKEVEE 812
+ E + RRQE+ QQ E+E+LLQE R Q+ K +EE ++ +++ E
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQ-ER 1705
Query: 813 EERRYYEE--------ERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQ 864
E + EE ERK E+ + + + E + + +
Sbjct: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765
Query: 865 DEKQDRRWKKSFQ--GDDSDLLLKTRESDR 892
+++DR++++ Q + + L+++ESDR
Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDR 1795
>gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens]
Length = 377
Score = 49.3 bits (116), Expect = 2e-05
Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 20/96 (20%)
Query: 983 REHFQAGPFSPCSPT---PPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQC 1039
++ QA P +P +P+ PP + + +GK +CSSCGL + +++ NL +H++C
Sbjct: 66 KDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILD--RYLLKVNNLIWHVRC 123
Query: 1040 FRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSR 1075
C +C R L N CY++++
Sbjct: 124 LECSVC---------------RTSLRQQNSCYIKNK 144
>gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]
Length = 392
Score = 49.3 bits (116), Expect = 2e-05
Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 20/96 (20%)
Query: 983 REHFQAGPFSPCSPT---PPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQC 1039
++ QA P +P +P+ PP + + +GK +CSSCGL + +++ NL +H++C
Sbjct: 66 KDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILD--RYLLKVNNLIWHVRC 123
Query: 1040 FRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSR 1075
C +C R L N CY++++
Sbjct: 124 LECSVC---------------RTSLRQQNSCYIKNK 144
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 48.9 bits (115), Expect = 3e-05
Identities = 51/224 (22%), Positives = 99/224 (44%), Gaps = 16/224 (7%)
Query: 773 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 832
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 147 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 204
Query: 833 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 891
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 205 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 258
Query: 892 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 948
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 259 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 318
Query: 949 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKKSPREHFQA 988
S+E+V + + D ++ NH + P R + E +A
Sbjct: 319 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEA 362
Score = 38.9 bits (89), Expect = 0.027
Identities = 38/122 (31%), Positives = 59/122 (48%), Gaps = 18/122 (14%)
Query: 327 SMFDMRCEEE--AAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSR------RRSV 378
SM D E++ A P +R+E++ ++ R+E KW+ AR K R R
Sbjct: 72 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKE--KWKH--ARVKEREHERRKRHRE 127
Query: 379 SQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEE 438
QD ++E ER+K ++ A E ER + E ++ K RER++ E K R Q+E
Sbjct: 128 EQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQKEQREQKE 181
Query: 439 AE 440
E
Sbjct: 182 RE 183
Score = 31.6 bits (70), Expect = 4.2
Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 7/91 (7%)
Query: 359 EEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQE 418
EEDD + SR+ V +K+E+RK+ K ++ ERR K +RE Q+
Sbjct: 78 EEDDSLAIKPPQQMSRKEKVHH---RKDEKRKEKWKHARVKEREHERR---KRHRE-EQD 130
Query: 419 KERRERELHEAYKNARSQEEAEGILQQYIER 449
K RRE E + + AR E + +ER
Sbjct: 131 KARREWERQKRREMAREHSRRERDRLEQLER 161
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 48.9 bits (115), Expect = 3e-05
Identities = 51/224 (22%), Positives = 99/224 (44%), Gaps = 16/224 (7%)
Query: 773 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 832
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 157 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 214
Query: 833 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 891
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 215 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 268
Query: 892 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 948
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 269 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 328
Query: 949 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKKSPREHFQA 988
S+E+V + + D ++ NH + P R + E +A
Sbjct: 329 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEA 372
Score = 33.9 bits (76), Expect = 0.86
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 372 KSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYK 431
+ +R QD ++E ER+K ++ A E ER + E ++ K RER++ E K
Sbjct: 131 RRKRHREEQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQK 184
Query: 432 NARSQEEAE 440
R Q+E E
Sbjct: 185 EQREQKERE 193
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 48.9 bits (115), Expect = 3e-05
Identities = 86/404 (21%), Positives = 156/404 (38%), Gaps = 71/404 (17%)
Query: 539 KPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARV 598
K + ++ L + VS+ E EEKE E + KS V
Sbjct: 85 KVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSP-------V 137
Query: 599 HGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSE 658
+ E+K++ G E + ++ A +++ E +GG ++G+ E E
Sbjct: 138 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE--------EGGSEKEGSSEKEEGE 189
Query: 659 PQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPEN---EMSGKVELVLSQKVVK 715
+ E + + + + +E K++KK E E++ K ELV KV K
Sbjct: 190 QE----------------EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 233
Query: 716 P---KSPEPEATLTFPF---LDKMPEANQLHLPNLNSQVDSPSSE---KSPVMTPQFKFW 766
P KSP P++ + + K P + P S V+ KSPV
Sbjct: 234 PEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 293
Query: 767 AWDPEEERRRQ-------EKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYE 819
+ P EE+ + E+ + + E E+ ++E+ ++KE ++ + E +EE+ +
Sbjct: 294 SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVP 353
Query: 820 EERK----IIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDL------GNCQDEKQD 869
E++K + E+ V + S + EG + + G ++E D
Sbjct: 354 EKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSD 413
Query: 870 RRWKKSFQGD-----------DSDLLLKTRESDRLEEKGSLTEG 902
+ K S + D + + K + S R EEKG +T G
Sbjct: 414 KGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNG 457
Score = 45.8 bits (107), Expect = 2e-04
Identities = 78/362 (21%), Positives = 150/362 (41%), Gaps = 42/362 (11%)
Query: 319 VSDDAESTSMFDMRCEEEAAVQPHSR----ARQEQLQLINNQLREEDDKWQDDLARWKSR 374
V + E T + D + E E A+ + + +E+ + + EE + ++++A KS
Sbjct: 77 VEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSP 136
Query: 375 RRS----VSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAY 430
++ V ++ +KEEE + E+ E S++ + + +E EKE E+E E
Sbjct: 137 VKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE 196
Query: 431 KNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTE-PNLSSFLND------- 482
A EEAE ++ +E + A E L +E+ + P S + +
Sbjct: 197 AEAEG-EEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP 255
Query: 483 PNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYS 542
+P++ + +P ++ + ++ V + S S SP V KA + P
Sbjct: 256 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSP---VEEKAKSPVPKSPVE 312
Query: 543 QPKNSQDVLK-----TFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVAR 597
+ K+ +V K + + K + E V ++EEK ++ P A S K + V
Sbjct: 313 EAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVT 372
Query: 598 VHGSPLELKQDNGSIEINIKKPNS-----VPQELAATTEKTEPNSQEDKNDGGK--SRKG 650
+ S++++++K + QE E S+E+ +D G SRK
Sbjct: 373 I----------TKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKE 422
Query: 651 NI 652
+I
Sbjct: 423 DI 424
Score = 44.3 bits (103), Expect = 6e-04
Identities = 57/311 (18%), Positives = 126/311 (40%), Gaps = 49/311 (15%)
Query: 707 LVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFW 766
+ +S K+ KPK P+ + F++++ E ++V+ SE +T +
Sbjct: 54 ITISSKIQKPKVEAPKLKVQHKFVEEIIE---------ETKVEDEKSEMEEALTAITEEL 104
Query: 767 AWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIE 826
A +EE++ + ++E+ +E ++ +K + ++E E+E +EE + +
Sbjct: 105 AVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEED 164
Query: 827 DTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLK 886
+ + +DQ S EGS + E+++ + +G++++
Sbjct: 165 E--------GAKSDQAEEGGSEKEGSSEKE-------EGEQEEGETEAEAEGEEAE---- 205
Query: 887 TRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQT 946
+E ++EEK E+ D + P +P + + P + +
Sbjct: 206 AKEEKKVEEKSE-------------EVATKEELVADAKVEKPEKAKSP-VPKSPVEEKGK 251
Query: 947 SNPTHSSEDVK-----PKTLPLDKSINHQIESPSERRKKSP--REHFQAGPFSPCSPTPP 999
S S + K PK+ +K + +SP E + KSP + + SP +P
Sbjct: 252 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPV 311
Query: 1000 GQSPNRSISGK 1010
++ +++ GK
Sbjct: 312 EEAKSKAEVGK 322
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 48.9 bits (115), Expect = 3e-05
Identities = 51/224 (22%), Positives = 99/224 (44%), Gaps = 16/224 (7%)
Query: 773 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 832
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 148 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 205
Query: 833 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 891
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 206 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 259
Query: 892 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 948
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 260 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 319
Query: 949 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKKSPREHFQA 988
S+E+V + + D ++ NH + P R + E +A
Sbjct: 320 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEA 363
Score = 35.4 bits (80), Expect = 0.29
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 11/119 (9%)
Query: 327 SMFDMRCEEE--AAVQPHSRARQEQLQLINNQLREEDDKW---QDDLARWKSRRRSVSQD 381
SM D E++ A P +R+E++ ++ R+E + + + +R QD
Sbjct: 72 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQD 131
Query: 382 LIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAE 440
++E ER+K ++ A E ER + E ++ K RER++ E K R Q+E E
Sbjct: 132 KARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQKEQREQKERE 184
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 48.9 bits (115), Expect = 3e-05
Identities = 51/224 (22%), Positives = 99/224 (44%), Gaps = 16/224 (7%)
Query: 773 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 832
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 125 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 182
Query: 833 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 891
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 183 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 236
Query: 892 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 948
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 237 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 296
Query: 949 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKKSPREHFQA 988
S+E+V + + D ++ NH + P R + E +A
Sbjct: 297 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEA 340
Score = 33.9 bits (76), Expect = 0.86
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 372 KSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYK 431
+ +R QD ++E ER+K ++ A E ER + E ++ K RER++ E K
Sbjct: 99 RRKRHREEQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQK 152
Query: 432 NARSQEEAE 440
R Q+E E
Sbjct: 153 EQREQKERE 161
Score = 30.8 bits (68), Expect = 7.2
Identities = 28/113 (24%), Positives = 51/113 (45%), Gaps = 8/113 (7%)
Query: 327 SMFDMRCEEE--AAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIK 384
SM D E++ A P +R+E++ ++ R+E + + A R ++
Sbjct: 38 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKE--- 94
Query: 385 KEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQE 437
+E ER+K + E + R + RE+ +E RRER+ E + R +E
Sbjct: 95 REHERRKRHR---EEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERE 144
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 48.9 bits (115), Expect = 3e-05
Identities = 51/224 (22%), Positives = 99/224 (44%), Gaps = 16/224 (7%)
Query: 773 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 832
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 114 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 171
Query: 833 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 891
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 172 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 225
Query: 892 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 948
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 226 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 285
Query: 949 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKKSPREHFQA 988
S+E+V + + D ++ NH + P R + E +A
Sbjct: 286 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEA 329
Score = 35.4 bits (80), Expect = 0.29
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 11/119 (9%)
Query: 327 SMFDMRCEEE--AAVQPHSRARQEQLQLINNQLREEDDKW---QDDLARWKSRRRSVSQD 381
SM D E++ A P +R+E++ ++ R+E + + + +R QD
Sbjct: 38 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQD 97
Query: 382 LIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAE 440
++E ER+K ++ A E ER + E ++ K RER++ E K R Q+E E
Sbjct: 98 KARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQKEQREQKERE 150
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,685,679
Number of Sequences: 37866
Number of extensions: 2583535
Number of successful extensions: 27609
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 308
Number of HSP's successfully gapped in prelim test: 837
Number of HSP's that attempted gapping in prelim test: 13942
Number of HSP's gapped (non-prelim): 8164
length of query: 1083
length of database: 18,247,518
effective HSP length: 113
effective length of query: 970
effective length of database: 13,968,660
effective search space: 13549600200
effective search space used: 13549600200
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.