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Search of human proteins with 16306532
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
(796 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 1615 0.0
gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens] 1076 0.0
gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 926 0.0
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 924 0.0
gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] 923 0.0
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 921 0.0
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 921 0.0
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 904 0.0
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 891 0.0
gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] 890 0.0
gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens] 857 0.0
gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens] 838 0.0
gi|16753221 cadherin 22 precursor [Homo sapiens] 782 0.0
gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens] 685 0.0
gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens] 538 e-153
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 447 e-125
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 447 e-125
gi|4826669 cadherin 15 preproprotein [Homo sapiens] 383 e-106
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 374 e-103
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 357 2e-98
gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 265 1e-70
gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 259 9e-69
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 248 2e-65
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 245 1e-64
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 237 3e-62
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 237 3e-62
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 234 3e-61
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 222 9e-58
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 205 1e-52
gi|221316595 cadherin 17 precursor [Homo sapiens] 204 2e-52
>gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
Length = 796
Score = 1615 bits (4181), Expect = 0.0
Identities = 796/796 (100%), Positives = 796/796 (100%)
Query: 1 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF 60
MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF
Sbjct: 1 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF 60
Query: 61 FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE 120
FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE
Sbjct: 61 FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE 120
Query: 121 RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ 180
RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ
Sbjct: 121 RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ 180
Query: 181 VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD 240
VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD
Sbjct: 181 VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD 240
Query: 241 MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN 300
MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN
Sbjct: 241 MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN 300
Query: 301 GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS 360
GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS
Sbjct: 301 GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS 360
Query: 361 NGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS 420
NGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS
Sbjct: 361 NGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS 420
Query: 421 IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD 480
IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD
Sbjct: 421 IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD 480
Query: 481 VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN 540
VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN
Sbjct: 481 VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN 540
Query: 541 FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA 600
FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA
Sbjct: 541 FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA 600
Query: 601 LLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENI 660
LLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENI
Sbjct: 601 LLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENI 660
Query: 661 ITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDF 720
ITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDF
Sbjct: 661 ITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDF 720
Query: 721 INTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFK 780
INTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFK
Sbjct: 721 INTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFK 780
Query: 781 KLADLYGSKDTFDDDS 796
KLADLYGSKDTFDDDS
Sbjct: 781 KLADLYGSKDTFDDDS 796
>gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens]
Length = 799
Score = 1076 bits (2782), Expect = 0.0
Identities = 519/745 (69%), Positives = 621/745 (83%), Gaps = 4/745 (0%)
Query: 42 GKEGQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIF 101
G+E ++L RSKRGWVWNQ FV+EE++GP+P+LVGRLH+D+D G IKYILSG+GAGTIF
Sbjct: 50 GEEQRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGTIF 109
Query: 102 VIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLH 161
I+D +G+IHA K LDREE+A+YTL AQAVD +T++PLEPPSEFI+KVQDINDN PEFL+
Sbjct: 110 QINDVTGDIHAIKRLDREEKAEYTLTAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLN 169
Query: 162 ETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTAL 221
YHA VPE S +GTSV VTA+DADDP YGNSAKLVYSILEGQPYFS+E +T II+TAL
Sbjct: 170 GPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETAIIKTAL 229
Query: 222 PNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAA 281
PNMDREAKEEY VVIQAKDMGGH GGLSGTT +T+TLTDVNDNPPKF QS+Y SV E
Sbjct: 230 PNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDV 289
Query: 282 VPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKR 341
V G +GRVKA D DIGEN +Y+I+DGDG FEIT+D + Q+G+I+L+KP+DFETK+
Sbjct: 290 VLGTAIGRVKANDQDIGENAQSSYDIIDGDGTALFEITSDAQAQDGIIRLRKPLDFETKK 349
Query: 342 AYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTV 401
+Y+LKVEAANVHIDP+F GPFKDT TVKI VEDADEPP+F +P+Y+ EV ENAA +V
Sbjct: 350 SYTLKVEAANVHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENAALNSV 409
Query: 402 VGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAA 461
+G+V A+DPD +SPIR+SIDRHTDL+R F IN +DG I PLDRE + W NIT+ A
Sbjct: 410 IGQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVWHNITIIAT 469
Query: 462 EIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDT 521
EI N Q ++VPVAI+VLDVNDNAP+FA+ YE F+CE+ KP Q I T+SA DKDD
Sbjct: 470 EIRNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENG--KP--GQVIQTVSAMDKDDP 525
Query: 522 ANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPP 581
NG F++SL PE+++NPNFT++ N DN+ + A+ GF+RQKQ++YLLPI+ISD G PP
Sbjct: 526 KNGHYFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIIISDSGNPP 585
Query: 582 MSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLR 641
+SST+TLTI+VCGC +G + SCN EAY+L GLS GALIAILACI++LLVIVVLFVTLR
Sbjct: 586 LSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPIGLSMGALIAILACIILLLVIVVLFVTLR 645
Query: 642 RQKKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQ 701
R K EPLI+ ++EDVRENII YDDEGGGEEDTEAFDIATLQNPDGINGF+PRKDIKP+ Q
Sbjct: 646 RHKNEPLIIKDDEDVRENIIRYDDEGGGEEDTEAFDIATLQNPDGINGFLPRKDIKPDLQ 705
Query: 702 YMPRPGLRPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESA 761
+MPR GL P PN VDVD+FIN R+ EADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLES
Sbjct: 706 FMPRQGLAPVPNGVDVDEFINVRLHEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLEST 765
Query: 762 TTDSDLDYDYLQNWGPRFKKLADLY 786
T+DSD ++DYL +WGPRFK+L +LY
Sbjct: 766 TSDSDQNFDYLSDWGPRFKRLGELY 790
>gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 926 bits (2393), Expect = 0.0
Identities = 467/782 (59%), Positives = 582/782 (74%), Gaps = 7/782 (0%)
Query: 6 CLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQFFVIEE 65
C+ LVCL + + A + + H E E +V R KRGWVWNQFFV+EE
Sbjct: 8 CICPVLVCLCFVQRCYGTAHHSSIKVMRNQTKHIEG--ETEVHHRPKRGWVWNQFFVLEE 65
Query: 66 YTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYT 125
+ GPDP VG+LHS+ D GDG++KYIL+GEGAGTIF+IDD +G+IH+TK+LDRE++ Y
Sbjct: 66 HMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYV 125
Query: 126 LMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTASD 185
L AQA+DR TN+PLEP SEFI+KVQDINDN P+F Y VPE S++GTSV+QVTA+D
Sbjct: 126 LHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATD 185
Query: 186 ADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHM 245
ADDPTYGNSA++VYSIL+GQPYFSV+ +TG+IRTAL NMDREA+E Y VVIQAKDM G +
Sbjct: 186 ADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQV 245
Query: 246 GGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTY 305
GGLSG+T V ITLTDVNDNPP+FPQ YQ+ V E+A G VG++KA D D G N +TY
Sbjct: 246 GGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNADMTY 305
Query: 306 NIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFK 365
+I++GDGM F I+TD ET+EG++ LKKP+++E K++Y+L +E AN H+D +F GPFK
Sbjct: 306 SIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFK 365
Query: 366 DTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSIDRHT 425
D +KI V D DEPP+F PSY+ EV ENA GTVVG V A+DPD+ NS +RY I+ +
Sbjct: 366 DATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVRYFINYNV 425
Query: 426 DLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNA 485
+ DRFF I+ G I+TTK LDREET W NITV A+EI N + V V IRVLDVNDN
Sbjct: 426 EDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNP 485
Query: 486 PKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRD 545
P+ A Y+ +CE+ +KP Q I TISA DKDD ANGPRF F L + NPNFT++D
Sbjct: 486 PELAREYDIIVCEN--SKP--GQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLKD 541
Query: 546 NRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCN 605
N DNTA + RR FSR QD+Y LPI+ISDGGIP +SS++TLTI+VC C+ +G + +C+
Sbjct: 542 NEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCH 601
Query: 606 AEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENIITYDD 665
AEA++ +AGLSTGALIAIL C++ILL IVVLF+TLRR KKEPLI+ EEDVREN++TYDD
Sbjct: 602 AEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSKKEPLII-SEEDVRENVVTYDD 660
Query: 666 EGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDFINTRI 725
EGGGEEDTEAFDI L+NP R+DI+PE + PR S+DV +FI R+
Sbjct: 661 EGGGEEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQTSSTLESIDVQEFIKQRL 720
Query: 726 QEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKKLADL 785
EAD DP+ PPYDS+Q Y YEG+ S AGS+SSL+SATT SD DY YL +WGP FKKLA+L
Sbjct: 721 AEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLGDWGPEFKKLAEL 780
Query: 786 YG 787
YG
Sbjct: 781 YG 782
>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
Length = 788
Score = 924 bits (2387), Expect = 0.0
Identities = 452/753 (60%), Positives = 577/753 (76%), Gaps = 9/753 (1%)
Query: 44 EGQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVI 103
+G++L R KRGW+WNQFF++EEYTG D VG+LHSD D GDG++KYILSG+GAGT+F+I
Sbjct: 45 DGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFII 104
Query: 104 DDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHET 163
D+K+G+IHAT+ +DREE+A YTL AQA++R T RP+EP SEF++K+ DINDN P F E
Sbjct: 105 DEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEI 164
Query: 164 YHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPN 223
Y A+VPE S VGTSV+QVTA+DADDP+YGNSA+++YSIL+GQPYFSVE +TGIIRTALPN
Sbjct: 165 YTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPN 224
Query: 224 MDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVP 283
M+RE +E+Y VVIQAKDMGG MGGLSGTT V ITLTDVNDNPP+FPQ+ + V E++
Sbjct: 225 MNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPV 284
Query: 284 GEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAY 343
G +G VKA D D G+N V Y I+DGDG + F+I T+ +TQEG+I +KKP+D+E++R Y
Sbjct: 285 GTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLY 344
Query: 344 SLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVG 403
+LKVEA N H+DP+F GPFKDT VKIS+ED DEPP+F SY+ EV E+ GT++G
Sbjct: 345 TLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIG 404
Query: 404 RVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEI 463
V A+DPD+ +SPIR+S+DRHTDLDR F I+ +G + T+KPLDRE + W N+TV AAEI
Sbjct: 405 TVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEI 464
Query: 464 HNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTAN 523
+N + +V V +R+LDVNDNAP+FA Y+ F+CE+ + Q I TISA DKDD
Sbjct: 465 NNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENAR----PGQLIQTISAVDKDDPLG 520
Query: 524 GPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMS 583
G +F FSL NPNFTV+DN DNTA + R+ GF+R + YLLP+VISD P S
Sbjct: 521 GQKFFFSLAAV---NPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQS 577
Query: 584 STNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQ 643
ST TLTI+VC CD G + SC+AEA +L AGLSTGALIAIL CI+ILLVIVVLF L+RQ
Sbjct: 578 STGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQ 637
Query: 644 KKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYM 703
+K+ ++ +ED+R+NI++Y+DEGGGEEDT+AFDI TL+NP I R+DI PE ++
Sbjct: 638 RKKEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFI 697
Query: 704 PRPGLRPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATT 763
PR AP++ DV DFIN R++E D DPTAPPYDS+ Y YEG S+A SLSSLES TT
Sbjct: 698 PR-RTPTAPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTT 756
Query: 764 DSDLDYDYLQNWGPRFKKLADLYGSKDTFDDDS 796
+ D +YDYL+ WGPRF KLA++YG ++ D DS
Sbjct: 757 EGDQNYDYLREWGPRFNKLAEMYGGGES-DKDS 788
>gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 923 bits (2386), Expect = 0.0
Identities = 451/755 (59%), Positives = 575/755 (76%), Gaps = 6/755 (0%)
Query: 42 GKEGQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIF 101
G L RSKR W+WNQFF++EEYTG D VG+LHSD D GDG++KYILSG+GAG +F
Sbjct: 42 GNSKNELNRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGDLF 101
Query: 102 VIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLH 161
+I++ +G+I ATK LDREE+ Y L AQA++R T RP+EP SEFI+K+ DINDN P F
Sbjct: 102 IINENTGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTK 161
Query: 162 ETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTAL 221
E Y A VPE S+VGT V+QVTA+DADDPTYGNSAK+VYSIL+GQPYFSVE++TGII+TAL
Sbjct: 162 EVYTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQPYFSVESETGIIKTAL 221
Query: 222 PNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAA 281
NMDRE +E+Y VVIQAKDMGG MGGLSGTT V ITLTDVNDNPP+FPQS YQ E++
Sbjct: 222 LNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFKTPESS 281
Query: 282 VPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKR 341
PG +GR+KA D D+GEN + Y+I DG+G++ F++ TD ETQEG+I +KK +DFE K+
Sbjct: 282 PPGTPIGRIKASDADVGENAEIEYSITDGEGLDMFDVITDQETQEGIITVKKLLDFEKKK 341
Query: 342 AYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTV 401
Y+LKVEA+N +++P+F+ GPFKD+ TV+I VED DEPP+F +YI +++E+A T
Sbjct: 342 VYTLKVEASNPYVEPRFLYLGPFKDSATVRIVVEDVDEPPVFSKLAYILQIREDAQINTT 401
Query: 402 VGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAA 461
+G V A+DPDAA +P++YS+DRHTD+DR F I+ +G I T+K LDRE W NITV A
Sbjct: 402 IGSVTAQDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRETLLWHNITVIAT 461
Query: 462 EIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDT 521
EI+N Q ++VP+ I+VLDVNDNAP+FA YE F+CE K ++Q I T+ A DKDD
Sbjct: 462 EINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCE----KAKADQLIQTLHAVDKDDP 517
Query: 522 ANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPP 581
+G +F FSL PE NFT++DN+DNTAG+ R+ G++R + YLLP+VISD P
Sbjct: 518 YSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLPVVISDNDYPV 577
Query: 582 MSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLR 641
SST T+T++VC CD +G + SC+AEA I GLSTGAL+AIL CIVILLV VVLF LR
Sbjct: 578 QSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGALVAILLCIVILLVTVVLFAALR 637
Query: 642 RQKKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQ 701
RQ+K+ ++ +ED+R+NI++Y+DEGGGEEDT+AFDI TL+NP+ I R+DI PE
Sbjct: 638 RQRKKEPLIISKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPEAIEDNKLRRDIVPEAL 697
Query: 702 YMPRPGLRPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESA 761
++PR A ++ DV DFIN R++E D DPTAPPYDS+ Y YEG GSVA SLSSLES
Sbjct: 698 FLPR-RTPTARDNTDVRDFINQRLKENDTDPTAPPYDSLATYAYEGTGSVADSLSSLESV 756
Query: 762 TTDSDLDYDYLQNWGPRFKKLADLYGSKDTFDDDS 796
TTD+D DYDYL +WGPRFKKLAD+YG D+ D DS
Sbjct: 757 TTDADQDYDYLSDWGPRFKKLADMYGGVDS-DKDS 790
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 921 bits (2380), Expect = 0.0
Identities = 459/787 (58%), Positives = 583/787 (74%), Gaps = 13/787 (1%)
Query: 2 KENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQFF 61
K +C L+ L + + A R +P F + G+ R+KR WVWNQFF
Sbjct: 5 KVEFCHFLQLIALFLCFSGMSQAELSRSRSKPYF----QSGRS-----RTKRSWVWNQFF 55
Query: 62 VIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREER 121
V+EEY G DP+ VG+LHSD+D GDG+IKYILSGEGA +IF+ID+ +G+IHATK LDREE+
Sbjct: 56 VLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQ 115
Query: 122 AQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQV 181
A YTL AQA+DR TN+P+EP SEF++K+QDINDN P+FL Y A VPE S VGTSV+QV
Sbjct: 116 AYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQV 175
Query: 182 TASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDM 241
TA+DADDPTYGNSA++VYSIL+GQPYFSVE +TG+I+TALPNMDREAK++Y +VIQAKDM
Sbjct: 176 TATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDM 235
Query: 242 GGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENG 301
G GGLSGTT VT+TLTDVNDNPP+FP+ YQ +V E+ V R+KA D DIG N
Sbjct: 236 VGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADIGANA 295
Query: 302 LVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISN 361
+ Y IVDGDG+ F+I+ D ETQEG+I ++K +DFE K +Y+L++EAAN DP+F+S
Sbjct: 296 EMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSL 355
Query: 362 GPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSI 421
GPF DT TVKI VED DEPP+F +P Y EV E G ++G V A DPD++NSP+RYSI
Sbjct: 356 GPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSI 415
Query: 422 DRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLDV 481
DR+TDL+R+F I+ G I T K LDRE A NITV A E N Q + VAI +LD+
Sbjct: 416 DRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQVGRGYVAITILDI 475
Query: 482 NDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNF 541
NDNAP+FA YE +CE+ Q Q I ISA DKD+ +NG +F FSL + +N NF
Sbjct: 476 NDNAPEFAMDYETTVCENAQ----PGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNF 531
Query: 542 TVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGAL 601
+++DN+DNTA + RR GF RQ+Q +Y LPI I D G P +SSTNTLTI+VC CD +G
Sbjct: 532 SLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVA 591
Query: 602 LSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENII 661
+CNAEAY+L AGLSTGALIAILAC++ LLV+++L VT+RR+KKEPLI EE D+RENI+
Sbjct: 592 QTCNAEAYVLPAGLSTGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEERDIRENIV 651
Query: 662 TYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDFI 721
YDDEGGGEEDTEAFD+A L+N + I R+D+ PE Q++ RP + P++V +FI
Sbjct: 652 RYDDEGGGEEDTEAFDMAALRNLNVIRDTKTRRDVTPEIQFLSRPAFKSIPDNVIFREFI 711
Query: 722 NTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKK 781
R++EAD DP APPYDS+Q Y +EG GSVA SLSSL+S +++SD +YDYL +WGPRFK+
Sbjct: 712 WERLKEADVDPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKR 771
Query: 782 LADLYGS 788
LAD+YG+
Sbjct: 772 LADMYGT 778
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 921 bits (2380), Expect = 0.0
Identities = 459/787 (58%), Positives = 583/787 (74%), Gaps = 13/787 (1%)
Query: 2 KENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQFF 61
K +C L+ L + + A R +P F + G+ R+KR WVWNQFF
Sbjct: 5 KVEFCHFLQLIALFLCFSGMSQAELSRSRSKPYF----QSGRS-----RTKRSWVWNQFF 55
Query: 62 VIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREER 121
V+EEY G DP+ VG+LHSD+D GDG+IKYILSGEGA +IF+ID+ +G+IHATK LDREE+
Sbjct: 56 VLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQ 115
Query: 122 AQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQV 181
A YTL AQA+DR TN+P+EP SEF++K+QDINDN P+FL Y A VPE S VGTSV+QV
Sbjct: 116 AYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQV 175
Query: 182 TASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDM 241
TA+DADDPTYGNSA++VYSIL+GQPYFSVE +TG+I+TALPNMDREAK++Y +VIQAKDM
Sbjct: 176 TATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDM 235
Query: 242 GGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENG 301
G GGLSGTT VT+TLTDVNDNPP+FP+ YQ +V E+ V R+KA D DIG N
Sbjct: 236 VGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADIGANA 295
Query: 302 LVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISN 361
+ Y IVDGDG+ F+I+ D ETQEG+I ++K +DFE K +Y+L++EAAN DP+F+S
Sbjct: 296 EMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSL 355
Query: 362 GPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSI 421
GPF DT TVKI VED DEPP+F +P Y EV E G ++G V A DPD++NSP+RYSI
Sbjct: 356 GPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSI 415
Query: 422 DRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLDV 481
DR+TDL+R+F I+ G I T K LDRE A NITV A E N Q + VAI +LD+
Sbjct: 416 DRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQVGRGYVAITILDI 475
Query: 482 NDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNF 541
NDNAP+FA YE +CE+ Q Q I ISA DKD+ +NG +F FSL + +N NF
Sbjct: 476 NDNAPEFAMDYETTVCENAQ----PGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNF 531
Query: 542 TVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGAL 601
+++DN+DNTA + RR GF RQ+Q +Y LPI I D G P +SSTNTLTI+VC CD +G
Sbjct: 532 SLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVA 591
Query: 602 LSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENII 661
+CNAEAY+L AGLSTGALIAILAC++ LLV+++L VT+RR+KKEPLI EE D+RENI+
Sbjct: 592 QTCNAEAYVLPAGLSTGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEERDIRENIV 651
Query: 662 TYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDFI 721
YDDEGGGEEDTEAFD+A L+N + I R+D+ PE Q++ RP + P++V +FI
Sbjct: 652 RYDDEGGGEEDTEAFDMAALRNLNVIRDTKTRRDVTPEIQFLSRPAFKSIPDNVIFREFI 711
Query: 722 NTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKK 781
R++EAD DP APPYDS+Q Y +EG GSVA SLSSL+S +++SD +YDYL +WGPRFK+
Sbjct: 712 WERLKEADVDPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKR 771
Query: 782 LADLYGS 788
LAD+YG+
Sbjct: 772 LADMYGT 778
>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
Length = 789
Score = 904 bits (2336), Expect = 0.0
Identities = 437/751 (58%), Positives = 568/751 (75%), Gaps = 5/751 (0%)
Query: 44 EGQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVI 103
+G++L+R+KRGW+WNQFF++EEYTG D VG+LH+D D GDGN+KYIL+G+GAG++FVI
Sbjct: 44 DGKMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVI 103
Query: 104 DDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHET 163
D+ +G+IHA K LDREE++ Y L A+A+DR T R +EP SEFI+K+ DINDN P+F +
Sbjct: 104 DENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDL 163
Query: 164 YHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPN 223
Y A+VPE S VGTSVIQVTA+DADD YGNSAK+VYSIL+GQPYFSV+ ++GII+TALP+
Sbjct: 164 YTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPD 223
Query: 224 MDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVP 283
M RE +E+Y VVIQAKDMGG MGGLSGTT V ITLTDVN+NPP+FPQS YQ + E+
Sbjct: 224 MSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPL 283
Query: 284 GEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAY 343
G +GR+KA DPD+GEN + Y+I +GDG + F++ TD +TQEG+I +K+ +DFE + Y
Sbjct: 284 GTHLGRIKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLY 343
Query: 344 SLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVG 403
+L+V+A+N H DP+F+ GPFKDT VKISVED DEPP+F SY+ EV E+ G+++G
Sbjct: 344 TLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIG 403
Query: 404 RVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEI 463
+V A DPDA N+ I+YS+DRHTD+DR F I+ E+G I T K LDRE + W NITV A EI
Sbjct: 404 QVTAYDPDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEI 463
Query: 464 HNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTAN 523
+N Q + +PV IR+LD+ND+AP+FA YE F+CE+ KP Q I T+S DKDD
Sbjct: 464 NNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCEN--AKP--GQLIQTVSVMDKDDPPR 519
Query: 524 GPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMS 583
G +F F PE NPNFT+ DN+DNTAG+ R+ G+SR K YLLPI+I D P S
Sbjct: 520 GHKFFFEPVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQS 579
Query: 584 STNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQ 643
ST TLTI+VC CD G + SC AEA IL+AGLSTGAL+AIL C++ILL++VVLF L+RQ
Sbjct: 580 STGTLTIRVCACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQ 639
Query: 644 KKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYM 703
+K+ ++ ++DVR+NI+TY+DEGGGEEDT+AFDI TL+NP+ R+D+ PE +
Sbjct: 640 RKKEPLIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQ 699
Query: 704 PRPGLRPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATT 763
R + P ++DV DFI+ R++E D DP+APPYDS+ Y YEG S+A SLSSLES T
Sbjct: 700 IRRTV-PLWENIDVQDFIHRRLKENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTA 758
Query: 764 DSDLDYDYLQNWGPRFKKLADLYGSKDTFDD 794
D + DYDYL +WGPRFKKLAD+YG D+ D
Sbjct: 759 DCNQDYDYLSDWGPRFKKLADMYGGDDSDRD 789
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 891 bits (2303), Expect = 0.0
Identities = 439/747 (58%), Positives = 561/747 (75%), Gaps = 5/747 (0%)
Query: 49 QRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSG 108
QR KRGWVWNQFFV+EEY G +P VG+LHSD+D G+G +KY LSG+GAGT+F ID+ +G
Sbjct: 50 QRVKRGWVWNQFFVLEEYVGSEPQYVGKLHSDLDKGEGTVKYTLSGDGAGTVFTIDETTG 109
Query: 109 NIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANV 168
+IHA ++LDREE+ YTL AQAVD +T +PLEP SEFI+KVQDINDN P+FL Y A V
Sbjct: 110 DIHAIRSLDREEKPFYTLRAQAVDIETRKPLEPESEFIIKVQDINDNEPKFLDGPYVATV 169
Query: 169 PERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREA 228
PE S VG V+QV A+DADDPTYGNSA++VYSIL+GQPYFS++ +TG+IRTALPNMDRE
Sbjct: 170 PEMSPVGAYVLQVKATDADDPTYGNSARVVYSILQGQPYFSIDPKTGVIRTALPNMDREV 229
Query: 229 KEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVG 288
KE+Y V+IQAKDMGG +GGL+GTT V ITLTDVNDNPP+FP+S++ + V E++ G +G
Sbjct: 230 KEQYQVLIQAKDMGGQLGGLAGTTIVNITLTDVNDNPPRFPKSIFHLKVPESSPIGSAIG 289
Query: 289 RVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVE 348
R++A DPD G+N + YNIV GDG F+I TD +TQEGVIKLKKP+DFETK+AY+ KVE
Sbjct: 290 RIRAVDPDFGQNAEIEYNIVPGDGGNLFDIVTDEDTQEGVIKLKKPLDFETKKAYTFKVE 349
Query: 349 AANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAK 408
A+N+H+D +F S GPFKDT TVKISV D DEPP+F P Y EV E+ GT++G V A+
Sbjct: 350 ASNLHLDHRFHSAGPFKDTATVKISVLDVDEPPVFSKPLYTMEVYEDTPVGTIIGAVTAQ 409
Query: 409 DPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQ 468
D D +S +RY ID +D D +FTI+ +G I T + LDRE TA N ++ A+++ N
Sbjct: 410 DLDVGSSAVRYFIDWKSDGDSYFTIDGNEGTIATNELLDRESTAQYNFSIIASKVSNPLL 469
Query: 469 EAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFI 528
+KV + I VLDVN+ P+ + PYE +CE+ KP Q I +SA D+D + G +F
Sbjct: 470 TSKVNILINVLDVNEFPPEISVPYETAVCEN--AKP--GQIIQIVSAADRDLSPAGQQFS 525
Query: 529 FSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTL 588
F L PE PNFTVRD R+NTAG+ RR G+SR++Q+LY LP+VI D P SSTNT+
Sbjct: 526 FRLSPEAAIKPNFTVRDFRNNTAGIETRRNGYSRRQQELYFLPVVIEDSSYPVQSSTNTM 585
Query: 589 TIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPL 648
TI+VC CD +G +LSCN EA L GLSTGALIAIL CIVILL IVVL+V LRRQKK+
Sbjct: 586 TIRVCRCDSDGTILSCNVEAIFLPVGLSTGALIAILLCIVILLAIVVLYVALRRQKKKDT 645
Query: 649 IVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGL 708
++ +ED+R+N+I YDDEGGGEEDT+AFDI L+NP I R+DIKP+ +PR
Sbjct: 646 LMTSKEDIRDNVIHYDDEGGGEEDTQAFDIGALRNPKVIEENKIRRDIKPDSLCLPRQ-R 704
Query: 709 RPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLD 768
P ++ D+ DFI+ R+QE D DPTAPPYDS+ Y YEG GSVA SLSS++S TT++D D
Sbjct: 705 PPMEDNTDIRDFIHQRLQENDVDPTAPPYDSLATYAYEGSGSVAESLSSIDSLTTEADQD 764
Query: 769 YDYLQNWGPRFKKLADLYGSKDTFDDD 795
YDYL +WGPRFK LAD++G +++++ D
Sbjct: 765 YDYLTDWGPRFKVLADMFGEEESYNPD 791
>gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens]
Length = 801
Score = 890 bits (2300), Expect = 0.0
Identities = 443/745 (59%), Positives = 567/745 (76%), Gaps = 7/745 (0%)
Query: 49 QRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSG 108
QR+KR WVWNQFFV+EEYTG DP+ VG+LHSD+D GDG+IKYILSGEGAG +F IDD +G
Sbjct: 55 QRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTG 114
Query: 109 NIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANV 168
+IHA + LDREERAQYTL AQA+DR T RP+EP SEFI+K+QDINDN P+FL Y A V
Sbjct: 115 DIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATV 174
Query: 169 PERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREA 228
PE S VGTSVIQVTA+DADDPTYGNSA++VYSIL+GQPYFSV+++TG+IRTAL NMDREA
Sbjct: 175 PEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREA 234
Query: 229 KEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVG 288
KE Y V+IQAKDMGG +GGL+GTT V ITL+DVNDNPP+FPQ YQMSV E+A VG
Sbjct: 235 KEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVG 294
Query: 289 RVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVE 348
RV AKD D G N + Y IVDGDG ++F+I+TD Q G+I +KKP+ FE+K++Y+LKVE
Sbjct: 295 RVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVE 354
Query: 349 AANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAK 408
AN H++ +F++ GPF+DT TV ISVED DEPP+F Y EV E+ A GT + + AK
Sbjct: 355 GANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAK 414
Query: 409 DPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQ 468
DPD N+ IRYSIDR +D RFF ++ G + T +PLDREE +W NITV A E++N Q
Sbjct: 415 DPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQ 474
Query: 469 EAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFI 528
VPV I+VLDVNDNAP+F YE F+CE+ + + Q I T+SA D+DD NG F
Sbjct: 475 VGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAK----AGQLIQTVSAVDQDDPRNGQHFY 530
Query: 529 FSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTL 588
+SL PE +NPNFT+RDN+DNTA + RR GF +Q+Q ++ LPI+I+D G P +SST TL
Sbjct: 531 YSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTL 590
Query: 589 TIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPL 648
TI+VC CD +G ++SC+ EAY+L LS GALIAILACI +LLV+V+L +++RR +K+P
Sbjct: 591 TIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVLVLLILSMRRHRKQPY 650
Query: 649 IVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNP-DGINGFIP--RKDIKPEYQYMPR 705
I+ +EE++ ENI+ YDDEGGGEEDTEAFDIA + NP + G P R+D+ PE + + R
Sbjct: 651 IIDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAAPKTRQDMLPEIESLSR 710
Query: 706 PGLRPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDS 765
+ + V ++ ++ EAD D APP+DS+Q Y +EG GSVAGSLSSL+SAT+DS
Sbjct: 711 YVPQTCAVNSTVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDS 770
Query: 766 DLDYDYLQNWGPRFKKLADLYGSKD 790
+ +D+L +WGPRF+KLA+LYG+ +
Sbjct: 771 EQSFDFLTDWGPRFRKLAELYGASE 795
>gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens]
Length = 781
Score = 857 bits (2213), Expect = 0.0
Identities = 432/752 (57%), Positives = 554/752 (73%), Gaps = 16/752 (2%)
Query: 45 GQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVID 104
G L R++R WVWNQFFVIEEY GP+PVL+G+LHSD+D G+G KY+L+GEGAGT+FVID
Sbjct: 36 GPALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVID 95
Query: 105 DKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETY 164
+ +GNIH TK+LDREE+AQY L+AQAVDR +NRPLEPPSEFI+KVQDINDNPP F Y
Sbjct: 96 EATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPY 155
Query: 165 HANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNM 224
HA VPE SNVGTSVIQVTA DADDP+YGNSAKLVY++L+G P+FSV+ QTG++RTA+PNM
Sbjct: 156 HATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNM 215
Query: 225 DREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPG 284
DRE +EE+ VVIQAKDMGGHMGGLSG+T VT+TL+DVNDNPPKFPQS+YQ SV E A PG
Sbjct: 216 DRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPG 275
Query: 285 EEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYS 344
VGR++A+DPD+G+N L+ Y+I+DG+G E+F I+TD + ++G++ ++KP+DFE++R+YS
Sbjct: 276 TLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYS 335
Query: 345 LKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGR 404
+VEA N IDP ++ GPFKD +V+++V+DA EPP F +Y V EN A GT+VG+
Sbjct: 336 FRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQ 395
Query: 405 VHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIH 464
+ A D D+ SPIRYSI H+D +R F+I PE+G I T PLDRE AW N+TV A E+
Sbjct: 396 ISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELD 455
Query: 465 NRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANG 524
+ Q ++V VAI+ LD NDNAP+ A PY+ F+C+S Q I I A D+D+ N
Sbjct: 456 SSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDS----AAPGQLIQVIRALDRDEVGNS 511
Query: 525 PRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSS 584
F P + + NFTV+DNRD +A + + + YL+PI + D G P +SS
Sbjct: 512 SHVSFQGP--LGPDANFTVQDNRDGSASLLLPSRP-APPRHAPYLVPIELWDWGQPALSS 568
Query: 585 TNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQK 644
T T+T+ VC C +G++ SC EA++ AGLSTGAL+AI+ C+ LL +VVLFV LRRQK
Sbjct: 569 TATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVALRRQK 628
Query: 645 KEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIP----RKDIKPEY 700
+E L+V EEEDVRENIITYDDEGGGEEDTEAFDI LQNPDG P R+D+ P
Sbjct: 629 QEALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARRDVLPRA 688
Query: 701 QYMPRPGLRPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLES 760
+ +P RP P DV + R++EAD DP PPYDS+Q+YGYEGRGS GSLSSL S
Sbjct: 689 RVSRQP--RP-PGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGS 745
Query: 761 ATTDSDL--DYDYLQNWGPRFKKLADLYGSKD 790
+ + L +WGP F+ LA+LYG+K+
Sbjct: 746 GSEAGGAPGPAEPLDDWGPLFRTLAELYGAKE 777
>gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens]
Length = 819
Score = 838 bits (2164), Expect = 0.0
Identities = 432/790 (54%), Positives = 554/790 (70%), Gaps = 54/790 (6%)
Query: 45 GQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVID 104
G L R++R WVWNQFFVIEEY GP+PVL+G+LHSD+D G+G KY+L+GEGAGT+FVID
Sbjct: 36 GPALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVID 95
Query: 105 DKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETY 164
+ +GNIH TK+LDREE+AQY L+AQAVDR +NRPLEPPSEFI+KVQDINDNPP F Y
Sbjct: 96 EATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPY 155
Query: 165 HANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNM 224
HA VPE SNVGTSVIQVTA DADDP+YGNSAKLVY++L+G P+FSV+ QTG++RTA+PNM
Sbjct: 156 HATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNM 215
Query: 225 DREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPG 284
DRE +EE+ VVIQAKDMGGHMGGLSG+T VT+TL+DVNDNPPKFPQS+YQ SV E A PG
Sbjct: 216 DRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPG 275
Query: 285 EEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYS 344
VGR++A+DPD+G+N L+ Y+I+DG+G E+F I+TD + ++G++ ++KP+DFE++R+YS
Sbjct: 276 TLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYS 335
Query: 345 LKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGR 404
+VEA N IDP ++ GPFKD +V+++V+DA EPP F +Y V EN A GT+VG+
Sbjct: 336 FRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQ 395
Query: 405 VHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEI- 463
+ A D D+ SPIRYSI H+D +R F+I PE+G I T PLDRE AW N+TV A E+
Sbjct: 396 ISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELG 455
Query: 464 -------------------------------------HNRHQEAKVPVAIRVLDVNDNAP 486
+ Q ++V VAI+ LD NDNAP
Sbjct: 456 WSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAP 515
Query: 487 KFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDN 546
+ A PY+ F+C+S Q I I A D+D+ N F P + + NFTV+DN
Sbjct: 516 QLAEPYDTFVCDS----AAPGQLIQVIRALDRDEVGNSSHVSFQGP--LGPDANFTVQDN 569
Query: 547 RDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNA 606
RD +A + + + YL+PI + D G P +SST T+T+ VC C +G++ SC
Sbjct: 570 RDGSASLLLPSRP-APPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVASCWP 628
Query: 607 EAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENIITYDDE 666
EA++ AGLSTGAL+AI+ C+ LL +VVLFV LRRQK+E L+V EEEDVRENIITYDDE
Sbjct: 629 EAHLSAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIITYDDE 688
Query: 667 GGGEEDTEAFDIATLQNPDGINGFIP----RKDIKPEYQYMPRPGLRPAPNSVDVDDFIN 722
GGGEEDTEAFDI LQNPDG P R+D+ P + +P RP P DV +
Sbjct: 689 GGGEEDTEAFDITALQNPDGAAPPAPGPPARRDVLPRARVSRQP--RP-PGPADVAQLLA 745
Query: 723 TRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDL--DYDYLQNWGPRFK 780
R++EAD DP PPYDS+Q+YGYEGRGS GSLSSL S + + L +WGP F+
Sbjct: 746 LRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFR 805
Query: 781 KLADLYGSKD 790
LA+LYG+K+
Sbjct: 806 TLAELYGAKE 815
>gi|16753221 cadherin 22 precursor [Homo sapiens]
Length = 828
Score = 782 bits (2020), Expect = 0.0
Identities = 399/779 (51%), Positives = 538/779 (69%), Gaps = 31/779 (3%)
Query: 33 PSFHGHHEKGKEGQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYIL 92
PS G + G G R KRGWVWNQFFV+EEYTG +P+ VG++HSD D GDG IKY +
Sbjct: 44 PSAPGARQDGALGA--GRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTI 101
Query: 93 SGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDI 152
SGEGAGTIF+ID+ +G+IHA + LDRE++ YTL AQA DR TNR LEP SEFI+KVQDI
Sbjct: 102 SGEGAGTIFLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDI 161
Query: 153 NDNPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEA 212
ND+ P FLH Y +V E S GTSV+QV ASDADDPTYG+SA+LVYS+L+G+ +F+V+
Sbjct: 162 NDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDP 221
Query: 213 QTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSV 272
+TG+IRTA+P++DRE++E Y VVIQA DM G +GGLSG+T VTI +TDVNDNPP+FPQ +
Sbjct: 222 KTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKM 281
Query: 273 YQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVD--GDGMESFEITTDYETQEGVIK 330
YQ S+ E+A G VGRVKA+D D+GEN +TY++ D G + F++TTD +TQE +I
Sbjct: 282 YQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIV 341
Query: 331 LKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIH 390
++K +DFE++ +++ +EA N +DP+F G F+D V+++V D DEPP F PS +
Sbjct: 342 VQKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLL 401
Query: 391 EVQENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREE 450
EVQE+A G++VG V A+DPDAAN P+RY+IDR +DLD+ F I+ + G I T K LDRE
Sbjct: 402 EVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRET 461
Query: 451 TAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPI 510
W NITV A E N Q ++ + IR+LDVNDN P+ A PYE +CE KP Q I
Sbjct: 462 AGWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCE--DAKP--GQLI 517
Query: 511 VTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLL 570
TIS D+D+ G RF F L PE NP+F++ D +DNTA V+ + GF+RQ+QD++ L
Sbjct: 518 QTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFL 577
Query: 571 PIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVIL 630
PI++ D G P +SST TLTI++CGCD +G + SCN A+++ A LS GALIA+L C++IL
Sbjct: 578 PILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLIL 637
Query: 631 LVIVVLFVTLRRQKKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQN------- 683
+V+V+L +TLRR K L E+ED+R+N+I Y+DEGGGE+DTEA+D++ L++
Sbjct: 638 VVLVLLILTLRRHHKSHLSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGEL 697
Query: 684 ----------------PDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDFINTRIQE 727
G G P+ + E +P+ P P+ DFI+ ++
Sbjct: 698 KGGDGGGSAGGGAGGGSGGGAGSPPQAHLPSERHSLPQGPPSPEPDFSVFRDFISRKVAL 757
Query: 728 ADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKKLADLY 786
AD D + PPYD+ Q Y +EG S A SLSSL S ++ S+ D+ YL +WGPRF+ LA LY
Sbjct: 758 ADGDLSVPPYDAFQTYAFEGADSPAASLSSLHSGSSGSEQDFAYLSSWGPRFRPLAALY 816
>gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens]
Length = 772
Score = 685 bits (1768), Expect = 0.0
Identities = 359/739 (48%), Positives = 498/739 (67%), Gaps = 12/739 (1%)
Query: 50 RSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGN 109
R KRGWVWNQFFV EE +G+L SD+D+G+ + +Y L G GAG+ F+ID+++G+
Sbjct: 40 RVKRGWVWNQFFVPEEMNTTSHH-IGQLRSDLDNGNNSFQYKLLGAGAGSTFIIDERTGD 98
Query: 110 IHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVP 169
I+A + LDREER+ Y L AQ +D T R +EP SEF++KV DINDN P+FL E Y A VP
Sbjct: 99 IYAIQKLDREERSLYILRAQVIDIATGRAVEPESEFVIKVSDINDNEPKFLDEPYEAIVP 158
Query: 170 ERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAK 229
E S GT VIQVTASDADDP+ GN+A+L+YS+L+GQPYFSVE TG+IR + MDRE +
Sbjct: 159 EMSPEGTLVIQVTASDADDPSSGNNARLLYSLLQGQPYFSVEPTTGVIRIS-SKMDRELQ 217
Query: 230 EEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGR 289
+EY V+IQAKDM G G LSGTT V I L+DVNDN P F +S+Y+++VSE+A G +G
Sbjct: 218 DEYWVIIQAKDMIGQPGALSGTTSVLIKLSDVNDNKPIFKESLYRLTVSESAPTGTSIGT 277
Query: 290 VKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEA 349
+ A D DIGEN + Y+I + D ++F+I T++ETQEG++ LKK VDFE + Y ++ +
Sbjct: 278 IMAYDNDIGENAEMDYSIEEDDS-QTFDIITNHETQEGIVILKKKVDFEHQNHYGIRAKV 336
Query: 350 ANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKD 409
N H+ + + T +KI VED DEPP+FL P Y+ EV E G+ VG V A D
Sbjct: 337 KNHHVPEQLMKYHTEASTTFIKIQVEDVDEPPLFLLPYYVFEVFEETPQGSFVGVVSATD 396
Query: 410 PDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQE 469
PD SPIRYSI R + F IN ++G I T+ LDRE +AW N+++ A E +N Q
Sbjct: 397 PDNRKSPIRYSITR----SKVFNIN-DNGTITTSNSLDREISAWYNLSITATEKYNIEQI 451
Query: 470 AKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIF 529
+ +P+ ++VL++ND+AP+F+ YE ++CE+ S Q I TISA D+D++ F F
Sbjct: 452 SSIPLYVQVLNINDHAPEFSQYYETYVCENAG----SGQVIQTISAVDRDESIEEHHFYF 507
Query: 530 SLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLT 589
+L E +N +FT+ DN+DNTA + R GF+ Q++ ++ + I+I+D GIP ++STNTLT
Sbjct: 508 NLSVEDTNNSSFTIIDNQDNTAVILTNRTGFNLQEEPVFYISILIADNGIPSLTSTNTLT 567
Query: 590 IKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLI 649
I VC C +G+ +C + +L+ G T +IAIL CI+I+ + L + L++++K+ L
Sbjct: 568 IHVCDCGDSGSTQTCQYQELVLSMGFKTEVIIAILICIMIIFGFIFLTLGLKQRRKQILF 627
Query: 650 VFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLR 709
+ ED RENI YDDEGGGEEDTEAFDIA L++ + RK E + + R L+
Sbjct: 628 PEKSEDFRENIFQYDDEGGGEEDTEAFDIAELRSSTIMRERKTRKTTSAEIRSLYRQSLQ 687
Query: 710 PAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDY 769
P+S FI +++EA+ DP APP+DS+Q Y +EG GS+AGSLSSLESA +D D Y
Sbjct: 688 VGPDSAIFRKFILEKLEEANTDPCAPPFDSLQTYAFEGTGSLAGSLSSLESAVSDQDESY 747
Query: 770 DYLQNWGPRFKKLADLYGS 788
DYL GPRFK+LA ++GS
Sbjct: 748 DYLNELGPRFKRLACMFGS 766
>gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens]
Length = 784
Score = 538 bits (1387), Expect = e-153
Identities = 315/753 (41%), Positives = 447/753 (59%), Gaps = 32/753 (4%)
Query: 49 QRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSG 108
+R KR W+WNQ + EE P VG++ S + N KY+L GE G +F +D ++G
Sbjct: 43 RRQKRDWIWNQMHIDEEKNTSLPHHVGKIKSSVSRK--NAKYLLKGEYVGKVFRVDAETG 100
Query: 109 NIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANV 168
++ A + LDRE ++Y L A VD+DT LE PS F +KV D+NDN P F H ++A+V
Sbjct: 101 DVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVHDVNDNWPVFTHRLFNASV 160
Query: 169 PERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREA 228
PE S VGTSVI VTA DADDPT G+ A ++Y IL+G+ YF+++ +G I T ++DRE
Sbjct: 161 PESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKEYFAID-NSGRIITITKSLDREK 219
Query: 229 KEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVG 288
+ Y +V++A+D G + G SGT V +TL D+NDN P F Q+ Y V E G VG
Sbjct: 220 QARYEIVVEARDAQG-LRGDSGTATVLVTLQDINDNFPFFTQTKYTFVVPEDTRVGTSVG 278
Query: 289 RVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVE 348
+ +DPD +N + Y+I+ GD ++F I T+ EG+IK KP+D+E + YS VE
Sbjct: 279 SLFVEDPDEPQNRMTKYSILRGDYQDAFTIETNPAHNEGIIKPMKPLDYEYIQQYSFIVE 338
Query: 349 AANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAK 408
A + ID +++S P + V I++ D DEPP+F P Y +++EN ++G V A
Sbjct: 339 ATDPTIDLRYMS-PPAGNRAQVIINITDVDEPPIFQQPFYHFQLKENQKK-PLIGTVLAM 396
Query: 409 DPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHN--- 465
DPDAA I YSI R +D +FF + + G I K LDRE W N+TV A E+ +
Sbjct: 397 DPDAARHSIGYSIRRTSDKGQFFRVT-KKGDIYNEKELDREVYPWYNLTVEAKELDSTGT 455
Query: 466 -RHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANG 524
+E+ V V I VLD NDNAP+FA PY+ +CE+ + Q ++ ISA DKD T
Sbjct: 456 PTGKESIVQVHIEVLDENDNAPEFAKPYQPKVCEN----AVHGQLVLQISAIDKDITPRN 511
Query: 525 PRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSS 584
+F F L E NFT+ DN DNTA + + G F R+ ++ LP+VISD G+P +
Sbjct: 512 VKFKFILNTE----NNFTLTDNHDNTANITVKYGQFDREHTKVHFLPVVISDNGMPSRTG 567
Query: 585 TNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQK 644
T+TLT+ VC C+ G C E G+S A++AIL CI+ + VI +L RR +
Sbjct: 568 TSTLTVAVCKCNEQGEFTFC--EDMAAQVGVSIQAVVAILLCILTITVITLLIFLRRRLR 625
Query: 645 KEPLIVFEE-EDVRENIITYDDEGGGEEDTEAFDIATLQN--PDGINGFIPRKDIKP--- 698
K+ + ++ E ++TYD+EGGGE DT ++D++ L + G P D +P
Sbjct: 626 KQARAHGKSVPEIHEQLVTYDEEGGGEMDTTSYDVSVLNSVRRGGAKPPRPALDARPSLY 685
Query: 699 -EYQYMPR--PGLRPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSL 755
+ Q PR PG P ++ I + EAD+D PPYD++ IYGYEG S+A SL
Sbjct: 686 AQVQKPPRHAPGAHGGPG--EMAAMIEVKKDEADHDGDGPPYDTLHIYGYEGSESIAESL 743
Query: 756 SSLESATTDSDLDYDYLQNWGPRFKKLADLYGS 788
SSL + ++DSD+DYD+L +WGPRFK LA+LYGS
Sbjct: 744 SSLGTDSSDSDVDYDFLNDWGPRFKMLAELYGS 776
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 447 bits (1151), Expect = e-125
Identities = 301/772 (38%), Positives = 423/772 (54%), Gaps = 49/772 (6%)
Query: 48 LQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGT----IFVI 103
LQR KR WV + E GP P + R+ SD D + +++Y ++G GA IF+I
Sbjct: 154 LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDK-NLSLRYSVTGPGADQPPTGIFII 212
Query: 104 DDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHET 163
+ SG + TK LDRE+ A++ L A AVD + N+ +E P + ++ V D+NDN PEFLH+
Sbjct: 213 NPISGQLSVTKPLDREQIARFHLRAHAVDINGNQ-VENPIDIVINVIDMNDNRPEFLHQV 271
Query: 164 YHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP------YFSVEAQTGII 217
++ VPE S GT V+ VTA DADDP N L Y I+ P F++ +TG I
Sbjct: 272 WNGTVPEGSKPGTYVMTVTAIDADDPNALNGM-LRYRIVSQAPSTPSPNMFTINNETGDI 330
Query: 218 RTALPNMDREAKEEYHVVIQAKDMGGHMG-GLSGTTKVTITLTDVNDNPPKFPQSVYQMS 276
T +DRE ++Y ++IQA DM G+ GLS T IT+TDVNDNPP+F +
Sbjct: 331 ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGE 390
Query: 277 VSEAAVPGEEVG-RVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPV 335
V E V V KD Y I GD F I TD + +G++ + KP+
Sbjct: 391 VPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPI 450
Query: 336 DFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQEN 395
DFET R + L V A N K I + P + T TV ++V D +E P F I +E
Sbjct: 451 DFETNRMFVLTVAAENQVPLAKGIQHPP-QSTATVSVTVIDVNENPYFAPNPKIIRQEEG 509
Query: 396 AAAGTVVGRVHAKDPDA-ANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDRE----E 450
AGT++ A+DPD IRY+ + +D + I+P +G I T LDRE +
Sbjct: 510 LHAGTMLTTFTAQDPDRYMQQNIRYT--KLSDPANWLKIDPVNGQITTIAVLDRESPNVK 567
Query: 451 TAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPI 510
N T A++ + I +LD+NDNAP+ P E CE+ ++
Sbjct: 568 NNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQ-VLPQEAETCETPDPNSIN---- 622
Query: 511 VTISADDKDDTANGPRFIFSLP-PEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYL 569
I+A D D N F F LP + N+T+ + A + + + +Y
Sbjct: 623 --ITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLK---IKFLEAGIYE 677
Query: 570 LPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVI 629
+PI+I+D G PP S+ + L +KVC CD NG C I+ AGL TGA+IAIL CI+I
Sbjct: 678 VPIIITDSGNPPKSNISILRVKVCQCDSNG---DCTDVDRIVGAGLGTGAIIAILLCIII 734
Query: 630 LLVIVVLFVT-LRRQKKE----PLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNP 684
LL++V++FV ++R+ KE L++ E+DVR+NI+ YD+EGGGEED + +D++ LQ P
Sbjct: 735 LLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQP 793
Query: 685 DGINGF------IPRKDIKPEYQYMPRPGLRPAPNSVDVDDFINTRIQEADNDPTAPPYD 738
D + I R D +P + P AP+ D+ DFIN ++ ADNDPTAPPYD
Sbjct: 794 DTVEPDAIKPVGIRRMDERPIHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAPPYD 853
Query: 739 SIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKKLADLYGSKD 790
S+ ++ YEG GS AGSLSSL S+++ + DYDYL +WGPRFKKLAD+YG D
Sbjct: 854 SLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGD 905
>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
Length = 916
Score = 447 bits (1150), Expect = e-125
Identities = 303/774 (39%), Positives = 430/774 (55%), Gaps = 60/774 (7%)
Query: 48 LQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGT----IFVI 103
L+R KR WV V E GP P + R+ SD D+ D I+Y ++G GA +F I
Sbjct: 164 LRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVFSI 222
Query: 104 DDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHET 163
D SG ++ T+ +DREE A Y L A AVD + N+ +E P + + V D+NDN PEF+++
Sbjct: 223 DSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNK-VENPIDLYIYVIDMNDNRPEFINQV 281
Query: 164 YHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPY------FSVEAQTGII 217
Y+ +V E S GT V+ VTA+DADD T N + Y I+ P F++ ++TG I
Sbjct: 282 YNGSVDEGSKPGTYVMTVTANDADDSTTANGM-VRYRIVTQTPQSPSQNMFTINSETGDI 340
Query: 218 RTALPNMDREAKEEYHVVIQAKDMGGHMG-GLSGTTKVTITLTDVNDNPPKFPQSVYQMS 276
T +DRE ++Y V++QA DM G++ GLS T IT+TDVNDNPP+F S +
Sbjct: 341 VTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGE 400
Query: 277 VSEAAVPGEEVG-RVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPV 335
V E V V +D N Y I+ GD F + TD T EG++ + K V
Sbjct: 401 VPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAV 460
Query: 336 DFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQEN 395
D+E RA+ L V +N I F+ T V IS+ D +E P F + + ++E
Sbjct: 461 DYELNRAFMLTVMVSNQAPLASGIQMS-FQSTAGVTISIMDINEAPYFPSNHKLIRLEEG 519
Query: 396 AAAGTVVGRVHAKDPDA-ANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWL 454
GTV+ A DPD +RYS + +D + IN +G I T LDRE
Sbjct: 520 VPPGTVLTTFSAVDPDRFMQQAVRYS--KLSDPASWLHINATNGQITTAAVLDRESLYTK 577
Query: 455 N----ITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPI 510
N T AA+ + I ++D+NDNAP+ P E ICE KP N
Sbjct: 578 NNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELL-PKEAQICE----KP--NLNA 630
Query: 511 VTISADDKDDTANGPRFIFSLP--PEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLY 568
+ I+A D D N ++F LP P + N+T+ + A + R + +Y
Sbjct: 631 INITAADADVDPNIGPYVFELPFVPAAVRK-NWTITRLNGDYAQLSLR---ILYLEAGMY 686
Query: 569 LLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIV 628
+PI+++D G PP+S+T+ + +KVC CD NG C + AGL TGA++AIL CI+
Sbjct: 687 DVPIIVTDSGNPPLSNTSIIKVKVCPCDDNG---DCTTIGAVAAAGLGTGAIVAILICIL 743
Query: 629 ILLVIVVLFVT-LRRQKKE----PLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQN 683
ILL +V+LFV ++R++KE L++ E+DVR+NI+ YD+EGGGEED + +D++ LQ
Sbjct: 744 ILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQ 802
Query: 684 PDGINGFIPRK-------DIKP---EYQYMPRPGLRPAPNSVDVDDFINTRIQEADNDPT 733
P+ + G +P K D +P E QY RP + P+ D+ DFIN ++ ADNDPT
Sbjct: 803 PEAM-GHVPSKAPGVRRVDERPVGAEPQYPIRPMV---PHPGDIGDFINEGLRAADNDPT 858
Query: 734 APPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKKLADLYG 787
APPYDS+ ++ YEG GS AGS+SSL S+++ D DYDYL +WGPRFKKLAD+YG
Sbjct: 859 APPYDSLLVFDYEGSGSTAGSVSSLNSSSS-GDQDYDYLNDWGPRFKKLADMYG 911
>gi|4826669 cadherin 15 preproprotein [Homo sapiens]
Length = 814
Score = 383 bits (984), Expect = e-106
Identities = 268/799 (33%), Positives = 410/799 (51%), Gaps = 41/799 (5%)
Query: 9 AALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQFFVIEEYTG 68
A L+ LG+L S + G RP+ + L R +R WV V E +
Sbjct: 4 AFLLVLGLLAQSLCLSLGVPGWRRPTTL---YPWRRAPALSRVRRAWVIPPISVSENHKR 60
Query: 69 -PDPVLVGRLHSDIDSGDGNIKYILSGEGAGT----IFVIDDKSGNIHATKTLDREERAQ 123
P P++ ++ SD G++ Y + G G +F ID +G + LDRE+ +
Sbjct: 61 LPYPLV--QIKSDKQQL-GSVIYSIQGPGVDEEPRGVFSIDKFTGKVFLNAMLDREKTDR 117
Query: 124 YTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTA 183
+ L A A+D + LE P++ + V D NDN P FL E + V E + GT V + A
Sbjct: 118 FRLRAFALDLGGST-LEDPTDLEIVVVDQNDNRPAFLQEAFTGRVLEGAVPGTYVTRAEA 176
Query: 184 SDADDPTYGNSAKLVYSILE-GQP-YFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDM 241
+DADDP N+A L +SIL+ G P FS++ TG IRT +DRE Y++ +Q DM
Sbjct: 177 TDADDPETDNAA-LRFSILQQGSPELFSIDELTGEIRTVQVGLDREVVAVYNLTLQVADM 235
Query: 242 GGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDI--GE 299
G GL+ T ITL D+NDN P+F + + M EA V G +VGR++ +D D+
Sbjct: 236 SGD--GLTATASAIITLDDINDNAPEFTRDEFFMEAIEA-VSGVDVGRLEVEDRDLPGSP 292
Query: 300 NGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFI 359
N + + I++GD F I TD +T EGV+ + K +D+E+ Y LKV N +
Sbjct: 293 NWVARFTILEGDPDGQFTIRTDPKTNEGVLSIVKALDYESCEHYELKVSVQN-EAPLQAA 351
Query: 360 SNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRY 419
+ + V++ V+D +EPP+F + E A GT+V A+DPD R
Sbjct: 352 ALRAERGQAKVRVHVQDTNEPPVFQENPLRTSLAEGAPPGTLVATFSARDPDTEQLQ-RL 410
Query: 420 SIDRHTDLDRFFTINPEDGFIKTTKPLDREET----AWLNITVFAAEIHNRHQEAKVPVA 475
S + D + + ++ G I+T L W V A + ++ + A ++
Sbjct: 411 SYSKDYDPEDWLQVDAATGRIQTQHVLSPASPFLKGGWYRAIVLAQDDASQPRTATGTLS 470
Query: 476 IRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEI 535
I +L+VND+AP A P G +C P + + A D+D +G F F L P +
Sbjct: 471 IEILEVNDHAPVLAPPPPGSLCSEPH-----QGPGLLLGATDEDLPPHGAPFHFQLSPRL 525
Query: 536 IHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGC 595
P + +AR + + L+ L +++ D G PP L + VC C
Sbjct: 526 ---PELGRNWSLSQVNVSHARLRPRHQVPEGLHRLSLLLRDSGQPPQQREQPLNVTVCRC 582
Query: 596 DVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEP----LIVF 651
+G L A GLS GAL+ +LA ++LLV+V+L R K+ L+
Sbjct: 583 GKDGVCLPGAAALLAGGTGLSLGALVIVLASALLLLVLVLLVALRARFWKQSRGKGLLHG 642
Query: 652 EEEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGIN---GFIPRKDIKPEYQYMPRPGL 708
++D+R+N++ YD++GGGEED +A+DI+ L++P ++ G P + P+ + P+P
Sbjct: 643 PQDDLRDNVLNYDEQGGGEEDQDAYDISQLRHPTALSLPLGPPPLRRDAPQGRLHPQPPR 702
Query: 709 RPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLD 768
+ +D+ DFIN ++ AD+DP+ PPYD+ IY YEG GSVAG+LSS+ S+ D D D
Sbjct: 703 VLPTSPLDIADFINDGLEAADSDPSVPPYDTALIYDYEGDGSVAGTLSSILSSQGDEDQD 762
Query: 769 YDYLQNWGPRFKKLADLYG 787
YDYL++WGPRF +LAD+YG
Sbjct: 763 YDYLRDWGPRFARLADMYG 781
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 374 bits (961), Expect = e-103
Identities = 277/795 (34%), Positives = 402/795 (50%), Gaps = 76/795 (9%)
Query: 30 HLRPSFHGHHEKGKEGQVL---------QRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSD 80
H RP H G + ++L +R KR WV E GP P + ++ S+
Sbjct: 122 HHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSN 181
Query: 81 IDSGDGNIKYILSGEGAGT----IFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTN 136
D +G + Y ++G+GA T +F+I+ ++G + T+ LDRE A YTL + AV + N
Sbjct: 182 KDK-EGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGN 240
Query: 137 RPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAK 196
+E P E ++ V D NDN PEF E + +V E + GTSV++VTA+DADD +A
Sbjct: 241 A-VEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAA 299
Query: 197 LVYSILEGQP------YFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSG 250
+ Y+IL P F++ TG+I +DRE+ Y +V+QA D+ G GLS
Sbjct: 300 IAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE--GLST 357
Query: 251 TTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGL--VTYNIV 308
T IT+TD NDNPP F + Y+ V E + +K D D Y I+
Sbjct: 358 TATAVITVTDTNDNPPIFNPTTYKGQVPENEA-NVVITTLKVTDADAPNTPAWEAVYTIL 416
Query: 309 DGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFK--- 365
+ DG + F +TT+ +G++K K +DFE K+ Y L V NV PF+
Sbjct: 417 NDDGGQ-FVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVV---------PFEVSL 466
Query: 366 --DTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDA-ANSPIRYSID 422
T TV + V D +E P+F+ P EV E+ G + A++PD I Y I
Sbjct: 467 TTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIW 526
Query: 423 RHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVL--- 479
R D + INP+ G I T LDRE+ + + + A I + V L
Sbjct: 527 R--DTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLI 584
Query: 480 --DVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIH 537
DVNDNAP P F CE + KP Q I I AD +T+ E+ H
Sbjct: 585 LSDVNDNAP-IPEPRTIFFCERNP-KP---QVINIIDADLPPNTS-------PFTAELTH 632
Query: 538 --NPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGC 595
+ N+T++ N D T + + + D Y + + + D + T++V C
Sbjct: 633 GASANWTIQYN-DPTQESIILKPKMALEVGD-YKINLKLMDN----QNKDQVTTLEVSVC 686
Query: 596 DVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQK---KEPLIVFE 652
D GA C +A + AGL A++ IL I+ LL++++L + R++ KEPL+
Sbjct: 687 DCEGAAGVCR-KAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLP-P 744
Query: 653 EEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAP 712
E+D R+N+ YD+EGGGEED + FD++ L + R D+ P +PR RPA
Sbjct: 745 EDDTRDNVYYYDEEGGGEEDQD-FDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPA- 802
Query: 713 NSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYL 772
N ++ +FI+ ++ AD DPTAPPYDS+ ++ YEG GS A SLSSL S+ +D D DYDYL
Sbjct: 803 NPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYL 862
Query: 773 QNWGPRFKKLADLYG 787
WG RFKKLAD+YG
Sbjct: 863 NEWGNRFKKLADMYG 877
>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
Length = 829
Score = 357 bits (916), Expect = 2e-98
Identities = 259/761 (34%), Positives = 385/761 (50%), Gaps = 55/761 (7%)
Query: 46 QVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGT----IF 101
++L+R KR WV V E GP P + +L S+ D D I Y ++G GA + +F
Sbjct: 100 RILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DTKIFYSITGPGADSPPEGVF 158
Query: 102 VIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLH 161
++ ++G + K LDREE A+Y L AV + +E P + V D ND+ P+F
Sbjct: 159 AVEKETGWLLLNKPLDREEIAKYELFGHAVS-ENGASVEDPMNISIIVTDQNDHKPKFTQ 217
Query: 162 ETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP------YFSVEAQTG 215
+T+ +V E GTSV+QVTA+D DD Y + + YSI +P F++ TG
Sbjct: 218 DTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTG 277
Query: 216 IIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQM 275
I +DRE EY + IQA DM G G + T + + D NDN P F Y+
Sbjct: 278 TISVISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVVEILDANDNAPMFDPQKYEA 335
Query: 276 SVSEAAVPGEEVGRVKAKDPDIGENGL--VTYNIVDGDGMESFEITTDYETQEGVIKLKK 333
V E AV G EV R+ D D + TY I+ GD + F ITT E+ +G++ +K
Sbjct: 336 HVPENAV-GHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRK 394
Query: 334 PVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQ 393
+DFE K ++L VE N + F+ P T T+ + VED +E P+F+ PS + EVQ
Sbjct: 395 GLDFEAKNQHTLYVEVTN---EAPFVLKLP-TSTATIVVHVEDVNEAPVFVPPSKVVEVQ 450
Query: 394 ENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAW 453
E G V A+DPD N I Y I R D + ++P+ G + LDRE+ +
Sbjct: 451 EGIPTGEPVCVYTAEDPDKENQKISYRILR--DPAGWLAMDPDSGQVTAVGTLDREDEQF 508
Query: 454 LN-----ITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQ 508
+ + V A + + + + ++DVND+ P P + IC + + N
Sbjct: 509 VRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGP-VPEPRQITICNQSPVRQVLN- 566
Query: 509 PIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLY 568
DKD + + F L + + +T N + V + + KQD Y
Sbjct: 567 ------ITDKDLSPHTSPFQAQLTDD--SDIYWTAEVNEEGDTVVLSLKKFL---KQDTY 615
Query: 569 LLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIV 628
+ + +SD G + I+ CD +G + +C G L A+LA +
Sbjct: 616 DVHLSLSDHG----NKEQLTVIRATVCDCHGHVETCPGP---WKGGFILPVLGAVLALLF 668
Query: 629 ILLVIVVLFVTLRRQKKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNP-DGI 687
+LLV+++L V +R+ KEPL++ E+D R+N+ Y +EGGGEED + +DI L +
Sbjct: 669 LLLVLLLL-VRKKRKIKEPLLL-PEDDTRDNVFYYGEEGGGEEDQD-YDITQLHRGLEAR 725
Query: 688 NGFIPRKDIKPEYQYMPRPGLRPAP-NSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYE 746
+ R D+ P +P P RP P N ++ +FI ++ A+ DPTAPPYD++ ++ YE
Sbjct: 726 PEVVLRNDVAPTI--IPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYE 783
Query: 747 GRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKKLADLYG 787
G GS A SLSSL S+ +D D DYDYL WG RFKKLAD+YG
Sbjct: 784 GSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYG 824
>gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
Length = 894
Score = 265 bits (678), Expect = 1e-70
Identities = 232/794 (29%), Positives = 363/794 (45%), Gaps = 92/794 (11%)
Query: 48 LQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAG----TIFVI 103
L+RSKR W ++E GP P V ++ SD + + I Y +SG G +F I
Sbjct: 129 LKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDA-AQNYTIFYSISGPGVDKEPFNLFYI 187
Query: 104 DDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHET 163
+ +G+I T+++DRE+ Q+ L A D P E P I+K++D NDN P F H
Sbjct: 188 EKDTGDIFCTRSIDREKYEQFALYGYATTADGYAP-EYPLPLIIKIEDDNDNAPYFEHRV 246
Query: 164 YHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP----YFSVEAQTGIIRT 219
VPE GTSV +VTA+D D+P ++ +L Y IL+ P +FS+ TG+I T
Sbjct: 247 TIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHPDTGVITT 305
Query: 220 ALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSE 279
P +DRE + Y ++++ +DMGG GL T +TI+L D NDNPP F ++ Y V E
Sbjct: 306 TTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEE 365
Query: 280 AAVPGEEVGRVKAKDPDIGE--NGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDF 337
+ E+ R+K +D D+ + Y I+ G+ +F I+TD T EGV+ + KP+++
Sbjct: 366 NRI-DVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNY 424
Query: 338 ETKRAYSLKVEAAN-VHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENA 396
E R L+V N S P T TV + + D+DE P P + + Q+
Sbjct: 425 EVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGF 484
Query: 397 AAGTVVGRVHAKDPD-AANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDRE----ET 451
AG + A DP+ ++ +RY + D D +F IN G ++T K LDRE +
Sbjct: 485 PAGQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKN 542
Query: 452 AWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIV 511
NI+V A + R + + + D ND+AP+ E IC+ +N+
Sbjct: 543 NQYNISVVAVDAVGR--SCTGTLVVHLDDYNDHAPQI--DKEVTICQ-------NNEDFA 591
Query: 512 TISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDL---- 567
+ D D NGP F F L N N +D + RQ+Q+L
Sbjct: 592 VLKPVDPDGPENGPPFQFFLDNSASKNWNIEEKDGKT----------AILRQRQNLDYNY 641
Query: 568 YLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTG---ALIAIL 624
Y +PI I D + +T+ LT++VC C + + + G L +L
Sbjct: 642 YSVPIQIKDR--HGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVL 699
Query: 625 ACIVILLVIVVLF-VTLRRQKKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQN 683
+++L ++ F VT +R K+ F E+ ++N+I + EG GEE TEA +Q
Sbjct: 700 GSVLLLCILFTCFCVTAKRTVKK---CFPEDIAQQNLIVSNTEGPGEEVTEANIRLPMQT 756
Query: 684 PDGIN-----GFIPRKDIKPEYQY-MPRPGLRPAPNS----------------------- 714
+ + G + + IK + + M + G N
Sbjct: 757 SNICDTSMSVGTVGGQGIKTQQSFEMVKGGYTLDSNKGGGHQTLESVKGVGQGDTGRYAY 816
Query: 715 VDVDDFINTRIQE-----ADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDY 769
D F R+ E ++ D + Y YEG+GS+AGS+ + L
Sbjct: 817 TDWQSFTQPRLGEKVYLCGQDEEHKHCEDYVCSYNYEGKGSLAGSVGCCSDRQEEEGL-- 874
Query: 770 DYLQNWGPRFKKLA 783
++L + P+F+ LA
Sbjct: 875 EFLDHLEPKFRTLA 888
>gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens]
Length = 840
Score = 259 bits (661), Expect = 9e-69
Identities = 205/652 (31%), Positives = 315/652 (48%), Gaps = 56/652 (8%)
Query: 48 LQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAG----TIFVI 103
L+RSKR W ++E GP P V ++ SD + + I Y +SG G +F I
Sbjct: 129 LKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDA-AQNYTIFYSISGPGVDKEPFNLFYI 187
Query: 104 DDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHET 163
+ +G+I T+++DRE+ Q+ L A D P E P I+K++D NDN P F H
Sbjct: 188 EKDTGDIFCTRSIDREKYEQFALYGYATTADGYAP-EYPLPLIIKIEDDNDNAPYFEHRV 246
Query: 164 YHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP----YFSVEAQTGIIRT 219
VPE GTSV +VTA+D D+P ++ +L Y IL+ P +FS+ TG+I T
Sbjct: 247 TIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHPDTGVITT 305
Query: 220 ALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSE 279
P +DRE + Y ++++ +DMGG GL T +TI+L D NDNPP F ++ Y V E
Sbjct: 306 TTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEE 365
Query: 280 AAVPGEEVGRVKAKDPDIGE--NGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDF 337
+ E+ R+K +D D+ + Y I+ G+ +F I+TD T EGV+ + KP+++
Sbjct: 366 NRI-DVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNY 424
Query: 338 ETKRAYSLKVEAAN-VHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENA 396
E R L+V N S P T TV + + D+DE P P + + Q+
Sbjct: 425 EVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGF 484
Query: 397 AAGTVVGRVHAKDPD-AANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDRE----ET 451
AG + A DP+ ++ +RY + D D +F IN G ++T K LDRE +
Sbjct: 485 PAGQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKN 542
Query: 452 AWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIV 511
NI+V A + R + + + D ND+AP+ E IC+ +N+
Sbjct: 543 NQYNISVVAVDAVGR--SCTGTLVVHLDDYNDHAPQI--DKEVTICQ-------NNEDFA 591
Query: 512 TISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDL---- 567
+ D D NGP F F L N N +D + RQ+Q+L
Sbjct: 592 VLKPVDPDGPENGPPFQFFLDNSASKNWNIEEKDGKT----------AILRQRQNLDYNY 641
Query: 568 YLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTG---ALIAIL 624
Y +PI I D + +T+ LT++VC C + + + G L +L
Sbjct: 642 YSVPIQIKDR--HGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVL 699
Query: 625 ACIVILLVIVVLF-VTLRRQKKEPLIVFEEEDVRENIITYDDEGGGEEDTEA 675
+++L ++ F VT +R K+ F E+ ++N+I + EG GEE TEA
Sbjct: 700 GSVLLLCILFTCFCVTAKRTVKK---CFPEDIAQQNLIVSNTEGPGEEVTEA 748
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 248 bits (633), Expect = 2e-65
Identities = 230/793 (29%), Positives = 369/793 (46%), Gaps = 78/793 (9%)
Query: 46 QVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAG----TIF 101
+VL+R+KR W ++E GP P+ + ++ SD + + I Y + G G +F
Sbjct: 128 KVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDT-AQNYTIYYSIRGPGVDQEPRNLF 186
Query: 102 VIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLH 161
++ +GN++ T+ +DRE+ + ++A A D P E P I+K++D NDN P F
Sbjct: 187 YVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTP-ELPLPLIIKIEDENDNYPIFTE 245
Query: 162 ETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP----YFSVEAQTGII 217
ETY + E VGT+V QV A+D D+P ++ +L YSI+ P FS+ TG+I
Sbjct: 246 ETYTFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPPSPTLFSMHPTTGVI 304
Query: 218 RTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSV 277
T +DRE ++Y + I+ +DM G GL T+ I + DVND+ P F ++ Y SV
Sbjct: 305 TTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSV 364
Query: 278 SEAAVPGEEVGRVKAKDPDI--GENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPV 335
E V E+ RV +D D+ N Y I+ G+ +F+I TD +T EGV+ + KP+
Sbjct: 365 EENTV-DVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPL 423
Query: 336 DFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQEN 395
++E K+ L++ N + S T TV ++VED DE P P ++EN
Sbjct: 424 NYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKEN 483
Query: 396 AAAGTVVGRVHAKDPDA-ANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDRE----E 450
A GT A DP+ ++S IRY + TD + TI+ G IK + LDRE +
Sbjct: 484 AEVGTTSNGYKAYDPETRSSSGIRYK--KLTDPTGWVTIDENTGSIKVFRSLDREAETIK 541
Query: 451 TAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPI 510
NITV A++ R + + ++ DVNDN+P F IC+ +S+ I
Sbjct: 542 NGIYNITVLASDQGGRTCTGTLGIILQ--DVNDNSP-FIPKKTVIICK----PTMSSAEI 594
Query: 511 VTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLL 570
V + D D+ +GP F FSL ++TA AR + Y++
Sbjct: 595 VAV---DPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTA---ARLSYQNDPPFGSYVV 648
Query: 571 PIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTG--ALIAILACIV 628
PI + D MSS +L + +C C + + + I G+ G A++AIL I
Sbjct: 649 PITVRDR--LGMSSVTSLDVTLCDC-ITENDCTHRVDPRIGGGGVQLGKWAILAILLGIA 705
Query: 629 ILLVIVVLFVTLRRQKKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQ----NP 684
+L I+ V + V ++ ++N+I + E G++ + + T Q +
Sbjct: 706 LLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASA 765
Query: 685 DGINGFIPR--KDIKPEYQYMPRPGLRPAPN----------------SVDVDD------- 719
G+ G + K+ E M + G + + + +VD+
Sbjct: 766 QGVCGTVGSGIKNGGQETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSE 825
Query: 720 ---FINTRIQEA-----DNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDY 771
F R+ E ++ D + Y YEGRGSVAGS+ + L ++
Sbjct: 826 WHSFTQPRLGEKVYLCNQDENHKHAQDYVLTYNYEGRGSVAGSVGCCSERQEEDGL--EF 883
Query: 772 LQNWGPRFKKLAD 784
L N P+F+ LA+
Sbjct: 884 LDNLEPKFRTLAE 896
>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
sapiens]
Length = 896
Score = 245 bits (625), Expect = 1e-64
Identities = 234/798 (29%), Positives = 359/798 (44%), Gaps = 95/798 (11%)
Query: 47 VLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAG----TIFV 102
VL+R+KR W + E GP P+ + ++ SD + + + Y +SG G +F
Sbjct: 129 VLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDA-AQNYTVFYSISGRGVDKEPLNLFY 187
Query: 103 IDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHE 162
I+ +GN+ T+ +DREE + L+A A D + P ++V+D NDN P F
Sbjct: 188 IERDTGNLFCTRPVDREEYDVFDLIAYASTAD-GYSADLPLPLPIRVEDENDNHPVFTEA 246
Query: 163 TYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP----YFSVEAQTGIIR 218
Y+ V E S GT+V V A+D D+P ++ +L YSIL+ P FSV TG+I
Sbjct: 247 IYNFEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPRSPGLFSVHPSTGVIT 305
Query: 219 TALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVS 278
T +DRE ++Y ++++ +DM G GL GT+ IT+TD NDN P F Q+ Y+ V
Sbjct: 306 TVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVE 365
Query: 279 EAAVPGEEVGRVKAKDPDI--GENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVD 336
E A E+ R+ +D D+ N V + I+ G+ F+I+TD ET EGV+ + KP++
Sbjct: 366 ENAF-NVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLN 424
Query: 337 FETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENA 396
+E R +L++ N + I + V + V D DE P + ++EN
Sbjct: 425 YEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENL 484
Query: 397 AAGTVVGRVHAKDPDAAN-SPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDRE----ET 451
A G+ + A DP+ N + +RY + D + TI+ G I T+K LDRE +
Sbjct: 485 AVGSKINGYKAYDPENRNGNGLRYK--KLHDPKGWITIDEISGSIITSKILDREVETPKN 542
Query: 452 AWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIV 511
NITV A + +R +A+ + DVNDN P+ Y IC KP
Sbjct: 543 ELYNITVLAIDKDDR--SCTGTLAVNIEDVNDNPPEILQEYV-VIC-----KP--KMGYT 592
Query: 512 TISADDKDDTANGPRFIFSLP---PEIIHNPNFT-VRDNRDNTAGVYARRGGFSRQKQDL 567
I A D D+ +G F FSLP PEI + T V D + Y + GF
Sbjct: 593 DILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLS--YQKNAGFQE----- 645
Query: 568 YLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACI 627
Y +PI + D ++T L + +C C C A + L A++AIL I
Sbjct: 646 YTIPITVKDRA--GQAATKLLRVNLCECT---HPTQCRATSRSTGVILGKWAILAILLGI 700
Query: 628 VILLVIVVLFVT----LRRQKKEPLIVFEEEDVRENIITYDDEGGGEEDT-EAFDIATLQ 682
+L +++ V + K+ F E+ ++N+I + E G++ A T
Sbjct: 701 ALLFSVLLTLVCGVFGATKGKR-----FPEDLAQQNLIISNTEAPGDDRVCSANGFMTQT 755
Query: 683 NPDGINGFI-----PRKDIKPEYQYMPRPGLRPAPN----------------SVDVDD-- 719
+ GF K+ E M + G + + +VD+
Sbjct: 756 TNNSSQGFCGTMGSGMKNGGQETIEMMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCR 815
Query: 720 --------FINTRIQEA-----DNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSD 766
F R+ E N+ P D + Y YEGRGS AGS+ +
Sbjct: 816 YTYSEWHSFTQPRLGEKLHRCNQNEDRMPSQDYVLTYNYEGRGSPAGSVGCCSEKQEEDG 875
Query: 767 LDYDYLQNWGPRFKKLAD 784
L D+L N P+F LA+
Sbjct: 876 L--DFLNNLEPKFITLAE 891
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 237 bits (605), Expect = 3e-62
Identities = 197/599 (32%), Positives = 304/599 (50%), Gaps = 41/599 (6%)
Query: 50 RSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGT----IFVIDD 105
R KR V + + E P P VG++ D D + + K+ L+G+G IF I++
Sbjct: 135 RQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPERS-KFRLTGKGVDQEPKGIFRINE 192
Query: 106 KSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYH 165
+G++ T+TLDRE A Y L + D + + LE P V V D NDN P F Y
Sbjct: 193 NTGSVSVTRTLDREVIAVYQLFVETTDVN-GKTLEGPVPLEVIVIDQNDNRPIFREGPYI 251
Query: 166 ANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP------YFSVEAQTGIIRT 219
+V E S GT+V+++TA DADDP N A L Y+I + P F ++ + G I T
Sbjct: 252 GHVMEGSPTGTTVMRMTAFDADDPATDN-ALLRYNIRQQTPDKPSPNMFYIDPEKGDIVT 310
Query: 220 ALPN--MDREAKE--EYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQM 275
+ +DRE E +Y ++I+A+DM G GL+GT TI + D ND+ PKF + +Q
Sbjct: 311 VVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQA 370
Query: 276 SVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPV 335
+V E AV V+ KD Y I++G+ +SFEI T+ +T EG++ + KP+
Sbjct: 371 TVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPL 430
Query: 336 DFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQEN 395
D+E ++L ++ N +S GP T TV I+V D +E P+F + QE+
Sbjct: 431 DYEISAFHTLLIKVENEDPLVPDVSYGP-SSTATVHITVLDVNEGPVFYPDPMMVTRQED 489
Query: 396 AAAGTVVGRVHAKDPDA-ANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDRE----E 450
+ G+V+ V+A DPD+ + IRYS+ + D + INP +G + TT LDRE +
Sbjct: 490 LSVGSVLLTVNATDPDSLQHQTIRYSV--YKDPAGWLNINPINGTVDTTAVLDRESPFVD 547
Query: 451 TAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPI 510
+ A + N + I + DVNDNAP F P +C D K LS +
Sbjct: 548 NSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAP-FIYPTVAEVC--DDAKNLS---V 601
Query: 511 VTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLL 570
V + A DKD N F F + + + + + + +NT + + ++ Y L
Sbjct: 602 VILGASDKDLHPNTDPFKFEIHKQAVPDKVWKI-SKINNTHALVSLLQNLNKAN---YNL 657
Query: 571 PIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAI--LACI 627
PI+++D G PPM++ L ++VC C + + CNA A L L + L+++ LAC+
Sbjct: 658 PIMVTDSGKPPMTNITDLRVQVCSC--RNSKVDCNA-AGALRFSLPSVLLLSLFSLACL 713
Score = 68.9 bits (167), Expect = 2e-11
Identities = 118/482 (24%), Positives = 191/482 (39%), Gaps = 72/482 (14%)
Query: 154 DNPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQ 213
D P F + +H N P S++ +T SD GN KL Y + PYF V +
Sbjct: 26 DCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCK----GND-KLRYEV--SSPYFKVNSD 78
Query: 214 TGIIRTALPNMDREAKEEY-------------HVVIQAKDMGGHMGGL---SGTTKVTIT 257
G++ AL N+ K + V++ KD+ G + + + T+ V
Sbjct: 79 GGLV--ALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQ 136
Query: 258 LTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFE 317
+ +P P++ Q +VG+V D +T VD + F
Sbjct: 137 KRSIVVSPILIPENQRQPF-------PRDVGKVVDSDRPERSKFRLTGKGVDQEPKGIFR 189
Query: 318 ITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDA 377
I + G + + + +D E Y L VE +V+ GP V V ++
Sbjct: 190 INEN----TGSVSVTRTLDREVIAVYQLFVETTDVN---GKTLEGPVPLEVIV---IDQN 239
Query: 378 DEPPMFLAPSYIHEVQENAAAGTVVGRV---HAKDPDAANSPIRYSIDRHT---DLDRFF 431
D P+F YI V E + GT V R+ A DP N+ +RY+I + T F
Sbjct: 240 DNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMF 299
Query: 432 TINPEDGFIKTTKP---LDRE--ETAWLNITVFAAEIHNRH--QEAKVPVAIRVLDVNDN 484
I+PE G I T LDRE E + + A ++ I + D ND+
Sbjct: 300 YIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDH 359
Query: 485 APKFA-APYEGFICESDQTKPLSNQPIVTISADDKDDTANGP-RFIFSLPPEIIHNP--N 540
+PKF ++ + E + IV ++ +DKDD G R +++ I NP +
Sbjct: 360 SPKFTKKEFQATVEEG------AVGVIVNLTVEDKDDPTTGAWRAAYTI---INGNPGQS 410
Query: 541 FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVI--SDGGIPPMS--STNTLTIKVCGCD 596
F + N G+ + + + L I + D +P +S ++T T+ + D
Sbjct: 411 FEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLD 470
Query: 597 VN 598
VN
Sbjct: 471 VN 472
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 237 bits (605), Expect = 3e-62
Identities = 198/643 (30%), Positives = 314/643 (48%), Gaps = 39/643 (6%)
Query: 46 QVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAG----TIF 101
+VL+R+KR W ++E GP P+ + ++ SD + + I Y + G G +F
Sbjct: 128 KVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDT-AQNYTIYYSIRGPGVDQEPRNLF 186
Query: 102 VIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLH 161
++ +GN++ T+ +DRE+ + ++A A D P E P I+K++D NDN P F
Sbjct: 187 YVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTP-ELPLPLIIKIEDENDNYPIFTE 245
Query: 162 ETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP----YFSVEAQTGII 217
ETY + E VGT+V QV A+D D+P ++ +L YSI+ P FS+ TG+I
Sbjct: 246 ETYTFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPPSPTLFSMHPTTGVI 304
Query: 218 RTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSV 277
T +DRE ++Y + I+ +DM G GL T+ I + DVND+ P F ++ Y SV
Sbjct: 305 TTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSV 364
Query: 278 SEAAVPGEEVGRVKAKDPDI--GENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPV 335
E V E+ RV +D D+ N Y I+ G+ +F+I TD +T EGV+ + KP+
Sbjct: 365 EENTV-DVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPL 423
Query: 336 DFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQEN 395
++E K+ L++ N + S T TV ++VED DE P P ++EN
Sbjct: 424 NYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKEN 483
Query: 396 AAAGTVVGRVHAKDPDA-ANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDRE----E 450
A GT A DP+ ++S IRY + TD + TI+ G IK + LDRE +
Sbjct: 484 AEVGTTSNGYKAYDPETRSSSGIRYK--KLTDPTGWVTIDENTGSIKVFRSLDREAETIK 541
Query: 451 TAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPI 510
NITV A++ R + + ++ DVNDN+P F IC+ +S+ I
Sbjct: 542 NGIYNITVLASDQGGRTCTGTLGIILQ--DVNDNSP-FIPKKTVIICK----PTMSSAEI 594
Query: 511 VTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLL 570
V + D D+ +GP F FSL ++TA AR + Y++
Sbjct: 595 VAV---DPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTA---ARLSYQNDPPFGSYVV 648
Query: 571 PIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTG--ALIAILACIV 628
PI + D MSS +L + +C C + + + I G+ G A++AIL I
Sbjct: 649 PITVRDR--LGMSSVTSLDVTLCDC-ITENDCTHRVDPRIGGGGVQLGKWAILAILLGIA 705
Query: 629 ILLVIVVLFVTLRRQKKEPLIVFEEEDVRENIITYDDEGGGEE 671
+L I+ V + V ++ ++N+I + E G++
Sbjct: 706 LLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
Length = 839
Score = 234 bits (596), Expect = 3e-61
Identities = 200/648 (30%), Positives = 310/648 (47%), Gaps = 56/648 (8%)
Query: 47 VLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAG----TIFV 102
VL+R+KR W + E GP P+ + ++ SD + + + Y +SG G +F
Sbjct: 129 VLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDA-AQNYTVFYSISGRGVDKEPLNLFY 187
Query: 103 IDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHE 162
I+ +GN+ T+ +DREE + L+A A D + P ++V+D NDN P F
Sbjct: 188 IERDTGNLFCTRPVDREEYDVFDLIAYASTAD-GYSADLPLPLPIRVEDENDNHPVFTEA 246
Query: 163 TYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP----YFSVEAQTGIIR 218
Y+ V E S GT+V V A+D D+P ++ +L YSIL+ P FSV TG+I
Sbjct: 247 IYNFEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPRSPGLFSVHPSTGVIT 305
Query: 219 TALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVS 278
T +DRE ++Y ++++ +DM G GL GT+ IT+TD NDN P F Q+ Y+ V
Sbjct: 306 TVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVE 365
Query: 279 EAAVPGEEVGRVKAKDPDI--GENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVD 336
E A E+ R+ +D D+ N V + I+ G+ F+I+TD ET EGV+ + KP++
Sbjct: 366 ENAF-NVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLN 424
Query: 337 FETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENA 396
+E R +L++ N + I + V + V D DE P + ++EN
Sbjct: 425 YEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENL 484
Query: 397 AAGTVVGRVHAKDPDAAN-SPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDRE----ET 451
A G+ + A DP+ N + +RY + D + TI+ G I T+K LDRE +
Sbjct: 485 AVGSKINGYKAYDPENRNGNGLRYK--KLHDPKGWITIDEISGSIITSKILDREVETPKN 542
Query: 452 AWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIV 511
NITV A + +R +A+ + DVNDN P+ Y IC KP
Sbjct: 543 ELYNITVLAIDKDDR--SCTGTLAVNIEDVNDNPPEILQEYV-VIC-----KP--KMGYT 592
Query: 512 TISADDKDDTANGPRFIFSLP---PEIIHNPNFT-VRDNRDNTAGVYARRGGFSRQKQDL 567
I A D D+ +G F FSLP PEI + T V D + Y + GF
Sbjct: 593 DILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLS--YQKNAGFQE----- 645
Query: 568 YLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACI 627
Y +PI + D ++T L + +C C C A + L A++AIL I
Sbjct: 646 YTIPITVKDRA--GQAATKLLRVNLCECT---HPTQCRATSRSTGVILGKWAILAILLGI 700
Query: 628 VILLVIVVLFVT----LRRQKKEPLIVFEEEDVRENIITYDDEGGGEE 671
+L +++ V + K+ F E+ ++N+I + E G++
Sbjct: 701 ALLFSVLLTLVCGVFGATKGKR-----FPEDLAQQNLIISNTEAPGDD 743
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 222 bits (566), Expect = 9e-58
Identities = 169/531 (31%), Positives = 268/531 (50%), Gaps = 54/531 (10%)
Query: 79 SDIDSG-DGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNR 137
+D+D+G +G + Y +SG + F+ID ++G + LDRE +YTL D
Sbjct: 742 TDLDTGFNGKLVYAVSGGNEDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGI-- 799
Query: 138 PLEPPSEFI-VKVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAK 196
P + + V V D NDNPPEFL E+Y V E V + +IQV A+D D G +
Sbjct: 800 PQKAAWRLLHVVVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKD---LGPNGH 856
Query: 197 LVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTI 256
+ YSI+ FS+++ TG++ A P +DRE + E+ + I+A+D L T V +
Sbjct: 857 VTYSIVTDTDTFSIDSVTGVVNIARP-LDRELQHEHSLKIEARDQAREEPQLFSTVVVKV 915
Query: 257 TLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVD-GDGMES 315
+L DVNDNPP F Y++ V E G + ++A DPD+G++G V Y+++D G+G
Sbjct: 916 SLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEG--- 972
Query: 316 FEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVE 375
D + G +++ + +DFE K+ Y+L V A + K +S T V++ V
Sbjct: 973 ---NFDVDKLSGAVRIVQQLDFEKKQVYNLTVRAKD---KGKPVS---LSSTCYVEVEVV 1023
Query: 376 DADE---PPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDA-ANSPIRYSIDRHTDLDRFF 431
D +E PP+F + V+E+A G++V V A D DA + IRYSI + + F
Sbjct: 1024 DVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSGVG-VF 1082
Query: 432 TINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAP 491
I E G I+T+ LDRE T+ +TVFA + + + + I V DVNDNAP+ + P
Sbjct: 1083 KIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEP 1142
Query: 492 YEGFICESDQTKPLSNQPIVTISADDKDDTAN----------GPRFIFSLPPEIIHNPNF 541
+ E + P + +V I A D D ++N P+ FS+ P+
Sbjct: 1143 V--YYPEIMENSP-KDVSVVQIEAFDPDSSSNDKLMYKITSGNPQGFFSIHPK------- 1192
Query: 542 TVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKV 592
T + R++QD ++L + ++D G PP S+ + +K+
Sbjct: 1193 --------TGLITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIARVIVKI 1235
Score = 214 bits (546), Expect = 2e-55
Identities = 170/538 (31%), Positives = 266/538 (49%), Gaps = 45/538 (8%)
Query: 67 TGPDPVLVGRLHSDIDSGDGNIK------YILSGEGAGTIFVIDDKSGNIHATKTLDREE 120
T P+ VL G+L I + D +I+ Y L G GA F ++ +G + + LDREE
Sbjct: 3031 TIPEDVLPGKLIMQISATDADIRSNAEITYTLLGSGAEK-FKLNPDTGELKTSTPLDREE 3089
Query: 121 RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ 180
+A Y L+ +A D + ++ ++D+NDN PEF + Y V E + GT + +
Sbjct: 3090 QAVYHLLVRATDGGGRFC---QASIVLTLEDVNDNAPEFSADPYAITVFENTEPGTLLTR 3146
Query: 181 VTASDADDPTYGNSAKLVYSILEGQP-YFSVEAQTGIIRTALPNMDREAKEEYHVVIQAK 239
V A+DAD G + K++YS+++ FS+ +GII+ P +DRE + Y + ++A
Sbjct: 3147 VQATDADA---GLNRKILYSLIDSADGQFSINELSGIIQLEKP-LDRELQAVYTLSLKAV 3202
Query: 240 DMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGE 299
D G L+ T V +++ D+NDNPP F Y +VSE + G EV +V A DI
Sbjct: 3203 DQGLPRR-LTATGTVIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEA 3261
Query: 300 NGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFI 359
N +TY+I+ G+ F I +++ G + + + +D+E+ Y L VEA +
Sbjct: 3262 NAEITYSIISGNEHGKFSI----DSKTGAVFIIENLDYESSHEYYLTVEATDG------- 3310
Query: 360 SNGPFKDTVTVKISVEDA-DEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDA-ANSPI 417
D TV ++V D D P+F +Y + E+A V V A D D +NS I
Sbjct: 3311 GTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSHI 3370
Query: 418 RYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIR 477
YSI FTI+P G +K TK LDRE + +TV A++ + + V I
Sbjct: 3371 HYSIIDGNQ-GSSFTIDPVRGEVKVTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNID 3429
Query: 478 VLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIH 537
V DVNDNAP F+ I + ++ S ++ + D+D + NGP F F++
Sbjct: 3430 VSDVNDNAPVFSRGNYSVIIQENKPVGFS---VLQLVVTDEDSSHNGPPFFFTI------ 3480
Query: 538 NPNFTVRDNRD---NTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKV 592
T D + N GV R+++D YLL + ++D G P +SS + I+V
Sbjct: 3481 ---VTGNDEKAFEVNPQGVLLTSSAIKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRV 3535
Score = 191 bits (486), Expect = 2e-48
Identities = 170/524 (32%), Positives = 256/524 (48%), Gaps = 51/524 (9%)
Query: 65 EYTGPDPVLVGRLHSDIDSG-DGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQ 123
E T P +L +D D+G + I Y L G F I++ SG I K LDRE +A
Sbjct: 3136 ENTEPGTLLTRVQATDADAGLNRKILYSLIDSADGQ-FSINELSGIIQLEKPLDRELQAV 3194
Query: 124 YTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTA 183
YTL +AVD+ R L IV V DINDNPP F + Y A V E VGT V+QV A
Sbjct: 3195 YTLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYA 3254
Query: 184 SDADDPTYGNSAKLVYSILEGQPY--FSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDM 241
+ D +A++ YSI+ G + FS++++TG + + N+D E+ EY++ ++A D
Sbjct: 3255 ASRDIEA---NAEITYSIISGNEHGKFSIDSKTGAV-FIIENLDYESSHEYYLTVEATD- 3309
Query: 242 GGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENG 301
G LS V + +TD+NDN P F Q Y +SE AV + V V A D D N
Sbjct: 3310 -GGTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNS 3368
Query: 302 LVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISN 361
+ Y+I+DG+ SF I + G +K+ K +D ET Y+L V+A++ P+
Sbjct: 3369 HIHYSIIDGNQGSSFTI----DPVRGEVKVTKLLDRETISGYTLTVQASDNGSPPRV--- 3421
Query: 362 GPFKDTVTVKISVEDA-DEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANS--PIR 418
+T TV I V D D P+F +Y +QEN G V ++ D D++++ P
Sbjct: 3422 ----NTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFF 3477
Query: 419 YSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRV 478
++I D ++ F +NP+ G + T+ + R+E + V A+ + + IRV
Sbjct: 3478 FTIVTGND-EKAFEVNPQ-GVLLTSSAIKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRV 3535
Query: 479 LDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKD--DTANGPRFIFSLPPEII 536
++ + P P E FI S + S I I A D+D DT +SL P++
Sbjct: 3536 IEESIYPPAI-LPLEIFITSSGE--EYSGGVIGKIHATDQDVYDT-----LTYSLDPQM- 3586
Query: 537 HNPNFTVRDNRDNTAGVYARRGG-FSRQKQDL--YLLPIVISDG 577
DN V + G + +K D+ YLL + ++DG
Sbjct: 3587 -----------DNLFSVSSTGGKLIAHKKLDIGQYLLNVSVTDG 3619
Score = 187 bits (475), Expect = 3e-47
Identities = 153/508 (30%), Positives = 251/508 (49%), Gaps = 44/508 (8%)
Query: 101 FVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFL 160
FVID +SG + K+LD E Y A + + + ++V+D NDN P F
Sbjct: 2751 FVIDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFE 2810
Query: 161 HETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPY-----FSVEAQTG 215
Y A + E G+ VIQ+ ASDAD G + +++YS+ + Q F++ +TG
Sbjct: 2811 SSPYEAFIVENLPGGSRVIQIRASDADS---GTNGQVMYSLDQSQSVEVIESFAINMETG 2867
Query: 216 IIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQM 275
I T L +D E ++ Y + + A D G + LS T V +T+TDVND+PP+F +Y+
Sbjct: 2868 WI-TTLKELDHEKRDNYQIKVVASDHGEKI-QLSSTAIVDVTVTDVNDSPPRFTAEIYKG 2925
Query: 276 SVSEAAVPGEEVGRVKAKDPDIGE-NGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKP 334
+VSE G + + D D E N VTY I GD + F + T E + +KKP
Sbjct: 2926 TVSEDDPQGGVIAILSTTDADSEEINRQVTYFITGGDPLGQFAVET--IQNEWKVYVKKP 2983
Query: 335 VDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDA-DEPPMFLAPSYIHEVQ 393
+D E + Y L + A ++G F V++ V DA D P+ Y +
Sbjct: 2984 LDREKRDNYLLTITA----------TDGTFSSKAIVEVKVLDANDNSPVCEKTLYSDTIP 3033
Query: 394 ENAAAGTVVGRVHAKDPD-AANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETA 452
E+ G ++ ++ A D D +N+ I Y++ + ++ F +NP+ G +KT+ PLDREE A
Sbjct: 3034 EDVLPGKLIMQISATDADIRSNAEITYTL-LGSGAEK-FKLNPDTGELKTSTPLDREEQA 3091
Query: 453 WLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAA-PYEGFICESDQTKPLSNQPIV 511
++ V A + R +A + + + DVNDNAP+F+A PY + E+ + L +
Sbjct: 3092 VYHLLVRATDGGGRFCQASIVLTLE--DVNDNAPEFSADPYAITVFENTEPGTL----LT 3145
Query: 512 TISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLP 571
+ A D D N + ++SL + F++ + +G+ R+ Q +Y L
Sbjct: 3146 RVQATDADAGLN-RKILYSLIDSA--DGQFSINE----LSGIIQLEKPLDRELQAVYTLS 3198
Query: 572 IVISDGGIP-PMSSTNTLTIKVCGCDVN 598
+ D G+P +++T T+ + V D+N
Sbjct: 3199 LKAVDQGLPRRLTATGTVIVSV--LDIN 3224
Score = 185 bits (470), Expect = 1e-46
Identities = 159/548 (29%), Positives = 252/548 (45%), Gaps = 42/548 (7%)
Query: 79 SDIDSGDGN--IKYILSGEGAGTIFVID--DKSGNIHATKTLDREERAQYTLMAQAVDRD 134
+D DS + N + Y ++G F ++ ++ K LDRE+R Y L A D
Sbjct: 2943 TDADSEEINRQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITATDGT 3002
Query: 135 TNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNS 194
+ VKV D NDN P Y +PE G ++Q++A+DAD ++
Sbjct: 3003 ----FSSKAIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDAD---IRSN 3055
Query: 195 AKLVYSIL-EGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTK 253
A++ Y++L G F + TG ++T+ P +DRE + YH++++A D GG S
Sbjct: 3056 AEITYTLLGSGAEKFKLNPDTGELKTSTP-LDREEQAVYHLLVRATDGGGRFCQAS---- 3110
Query: 254 VTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDG-DG 312
+ +TL DVNDN P+F Y ++V E PG + RV+A D D G N + Y+++D DG
Sbjct: 3111 IVLTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLIDSADG 3170
Query: 313 MESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKI 372
S + G+I+L+KP+D E + Y+L ++A + + + + G TV +
Sbjct: 3171 QFSINELS------GIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATG------TVIV 3218
Query: 373 SVEDA-DEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDA-ANSPIRYSIDRHTDLDRF 430
SV D D PP+F Y V E+ GT V +V+A D AN+ I YSI + +F
Sbjct: 3219 SVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGKF 3278
Query: 431 FTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAA 490
+I+ + G + + LD E + +TV A + V + V D+NDN P F+
Sbjct: 3279 -SIDSKTGAVFIIENLDYESSHEYYLTVEATDGGTPSLSDVATVNVNVTDINDNTPVFSQ 3337
Query: 491 PYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNT 550
+ D + Q ++T+ ADD D +N + +FT+ D
Sbjct: 3338 DTYTTVISEDA---VLEQSVITVMADDADGPSNSHIHYSIIDGN--QGSSFTI----DPV 3388
Query: 551 AGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYI 610
G R+ Y L + SD G PP +T T+ I V + N + S + I
Sbjct: 3389 RGEVKVTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFSRGNYSVI 3448
Query: 611 LNAGLSTG 618
+ G
Sbjct: 3449 IQENKPVG 3456
Score = 167 bits (424), Expect = 3e-41
Identities = 154/522 (29%), Positives = 241/522 (46%), Gaps = 36/522 (6%)
Query: 77 LHSDIDSGDG-NIKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDT 135
+H +S +G + Y ++ + F I+ +G I+ LD E Y L +A D T
Sbjct: 2202 VHVQANSPEGLKVFYSITDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLT 2261
Query: 136 NRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTASDAD-DPTYGNS 194
E + IV DINDNPP F ++Y + E S +GTSV+QV A+D+D +P G S
Sbjct: 2262 GAHAEVFVDIIV--DDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGIS 2319
Query: 195 AKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKV 254
++ + + +F V++ TG+I + L +D E ++ + ++A D G M LS V
Sbjct: 2320 YQMFGNHSKSHDHFHVDSSTGLI-SLLRTLDYEQSRQHTIFVRAVD--GGMPTLSSDVIV 2376
Query: 255 TITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGME 314
T+ +TD+NDNPP F Q +Y+ +SE A G V VKA D D + + Y+I+ G+ +
Sbjct: 2377 TVDVTDLNDNPPLFEQQIYEARISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHK 2436
Query: 315 SFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISV 374
F I ++ G+I L K YSL + +S+G F+ + V ++V
Sbjct: 2437 HFVI----DSATGIITLSNLHRHALKPFYSLNLS----------VSDGVFRSSTQVHVTV 2482
Query: 375 EDAD-EPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAA-NSPIRYSIDRHTDLDRFFT 432
+ P FL Y E+ ENA T+V V D D+ + Y I DRF+
Sbjct: 2483 IGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGHVTYHIVNDFAKDRFY- 2541
Query: 433 INPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPY 492
IN E G I T + LDRE A I+V + A V + + D NDNAP+F A
Sbjct: 2542 IN-ERGQIFTLEKLDRETPAEKVISVRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRATK 2600
Query: 493 EGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRD--NT 550
S K S +V + A D D+ +N I + +V++N +
Sbjct: 2601 YEVNIGSSAAKGTS---VVKVLASDADEGSNAD------ITYAIEADSESVKENLEINKL 2651
Query: 551 AGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKV 592
+GV + + + + + D G P S + +K+
Sbjct: 2652 SGVITTKESLIGLENEFFTFFVRAVDNGSPSKESVVLVYVKI 2693
Score = 159 bits (401), Expect = 1e-38
Identities = 137/466 (29%), Positives = 217/466 (46%), Gaps = 50/466 (10%)
Query: 72 VLVGRLHSDIDSGDGNIKY-ILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQA 130
V+ H + DG I+Y I G G G +F I +++G I + LDRE + Y L A
Sbjct: 1053 VMTVSAHDEDARRDGEIRYSIRDGSGVG-VFKIGEETGVIETSDRLDRESTSHYWLTVFA 1111
Query: 131 VDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTASDADDPT 190
D+ PL E ++V+D+NDN P+ Y+ + E S SV+Q+ +A DP
Sbjct: 1112 TDQGV-VPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQI---EAFDPD 1167
Query: 191 YGNSAKLVYSILEGQP--YFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGL 248
++ KL+Y I G P +FS+ +TG+I T +DRE ++E+ + + D G
Sbjct: 1168 SSSNDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGS--PPK 1225
Query: 249 SGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEE-------VGRVKAKDPDIGENG 301
S +V + + D NDN P+F Q Y++ + E P E + V A D D G N
Sbjct: 1226 STIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDEGPNA 1285
Query: 302 LVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISN 361
++Y+I DG+ F I E + GV+ K+ F Y + + K + N
Sbjct: 1286 EISYSIEDGNEHGKFFI----EPKTGVVSSKR---FSAAGEYDI--------LSIKAVDN 1330
Query: 362 GPFKDTVTVKISVEDADEPPMFLAPSYIHE------VQENAAAGTVVGRVHAKDPDAANS 415
G + + T ++ +E +P L P E V E+ ++G + + P
Sbjct: 1331 GRPQKSSTTRLHIEWISKPKPSLEPISFEESFFTFTVMESDPVAHMIGVISVEPP---GI 1387
Query: 416 PIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVA 475
P+ + I + D F ++ G I KPLD E+ + N+TV E + V
Sbjct: 1388 PLWFDI-TGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTV---EATDGTTTILTQVF 1443
Query: 476 IRVLDVNDNAPKFA-APYEGFICESDQTKPLSNQPIVTISADDKDD 520
I+V+D ND+ P+F+ + YE I E T P I+ ISA D+D+
Sbjct: 1444 IKVIDTNDHRPQFSTSKYEVVIPE--DTAP--ETEILQISAVDQDE 1485
Score = 150 bits (378), Expect = 6e-36
Identities = 145/519 (27%), Positives = 229/519 (44%), Gaps = 53/519 (10%)
Query: 87 NIKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFI 146
++ Y + G F I+ SG I K LD E YTL+ Q + L + +
Sbjct: 1696 SVVYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGTNM---AGLSTNTTVL 1752
Query: 147 VKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ-------VTASDADDPTYGNSAKLVY 199
V +QD NDN P F+ Y + E +++ + V+ + A+DAD + +A LVY
Sbjct: 1753 VHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDS---NALLVY 1809
Query: 200 SILEGQ--PYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTIT 257
I+E YF++++ TG I T L ++D E +H +Q DMG VT+
Sbjct: 1810 HIVEPSVHTYFAIDSSTGAIHTVL-SLDYEETSIFHFTVQVHDMGTPRLFAEYAANVTVH 1868
Query: 258 LTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFE 317
+ D+ND PP F + +Y+ S+ G +V V A D D + Y+I +G+ E F
Sbjct: 1869 VIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSITEGNIGEKFS 1928
Query: 318 ITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDA 377
+ DY+T G + ++ ++ Y L V A S+G F +VKI+V+++
Sbjct: 1929 M--DYKT--GALTVQNTTQLRSR--YELTVRA----------SDGRFAGLTSVKINVKES 1972
Query: 378 DEPPM-FLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPE 436
E + F Y V+EN+ + + A + N P+ Y I + DR F I+
Sbjct: 1973 KESHLKFTQDVYSAVVKENSTEAETLAVITAIG-NPINEPLFYHI---LNPDRRFKISRT 2028
Query: 437 DGFIKTT-KPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFA-APYEG 494
G + TT P DRE+ ++ V E H A V V + V D NDNAP F PY
Sbjct: 2029 SGVLSTTGTPFDREQQEAFDVVVEVTEEHKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYA 2088
Query: 495 FICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVY 554
+ + I ++A D+D NG + H+ +F + G
Sbjct: 2089 VVKVDTEV----GHVIRYVTAVDRDSGRNGEVHYYLKE----HHEHFQI-----GPLGEI 2135
Query: 555 ARRGGFSRQKQDL-YLLPIVISDGGIPPMSSTNTLTIKV 592
+ + F + YL+ +V DGG P S+ + I V
Sbjct: 2136 SLKKQFELDTLNKEYLVTVVAKDGGNPAFSAEVIVPITV 2174
Score = 147 bits (372), Expect = 3e-35
Identities = 138/519 (26%), Positives = 226/519 (43%), Gaps = 50/519 (9%)
Query: 92 LSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQD 151
++G + F +D +G I K LD E+++ Y L +A D T ++ +KV D
Sbjct: 1393 ITGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTIL----TQVFIKVID 1448
Query: 152 INDNPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP----- 206
ND+ P+F Y +PE + T ++Q++A D D+ KL+Y++ +
Sbjct: 1449 TNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEKN-----KLIYTLQSSRDPLSLK 1503
Query: 207 YFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPP 266
F ++ TG + T+ +D EA ++ + + +D + ++ + ++D ND+ P
Sbjct: 1504 KFRLDPATGSLYTS-EKLDHEAVHQHTLTVMVRDQDVPVK--RNFARIVVNVSDTNDHAP 1560
Query: 267 KFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQE 326
F S Y+ V E+A G V +V A D D G+N V Y+I G+ SF I +
Sbjct: 1561 WFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNSFMI----DPVL 1616
Query: 327 GVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADE-PPMFLA 385
G IK K +D + Y L V+A + + P + +V+I V AD P F +
Sbjct: 1617 GSIKTAKELDRSNQAEYDLMVKATDK-------GSPPMSEITSVRIFVTIADNASPKFTS 1669
Query: 386 PSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKP 445
Y E+ E + G+ VG V A + S + Y I D F INP G I T K
Sbjct: 1670 KEYSVELSETVSIGSFVGMVTAH----SQSSVVYEIKDGNTGDA-FDINPHSGTIITQKA 1724
Query: 446 LDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKF-AAPYEGFICESDQTKP 504
LD E + + + V + + D NDNAP F A Y G I ES
Sbjct: 1725 LDFETLPIYTLIIQGTNMAG--LSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINS 1782
Query: 505 L----SNQPIVTISAD-DKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGG 559
+ N P+V +AD DKD A ++ + +H F + D++ G
Sbjct: 1783 VVLTDRNVPLVIRAADADKDSNA---LLVYHIVEPSVHT-YFAI----DSSTGAIHTVLS 1834
Query: 560 FSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVN 598
++ ++ + + D G P + + + V D+N
Sbjct: 1835 LDYEETSIFHFTVQVHDMGTPRLFAEYAANVTVHVIDIN 1873
Score = 142 bits (358), Expect = 1e-33
Identities = 151/561 (26%), Positives = 244/561 (43%), Gaps = 50/561 (8%)
Query: 80 DIDSGD-GNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRP 138
D DS D ++Y + FVID +G I + + Y+L D
Sbjct: 2416 DADSSDIDKLQYSILSGNDHKHFVIDSATGIITLSNLHRHALKPFYSLNLSVSDG----V 2471
Query: 139 LEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGN-SAKL 197
++ V V N + P FL Y + E + + T V++V +D D YG+ + +
Sbjct: 2472 FRSSTQVHVTVIGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGHVTYHI 2531
Query: 198 VYSILEGQPYFSVEAQTGIIRTALPNMDRE--AKEEYHVVIQAKDMGGHMGGLSGTTKVT 255
V + + Y + Q L +DRE A++ V + AKD GG + + V
Sbjct: 2532 VNDFAKDRFYINERGQI----FTLEKLDRETPAEKVISVRLMAKDAGGKVAFCT----VN 2583
Query: 256 ITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMES 315
+ LTD NDN P+F + Y++++ +A G V +V A D D G N +TY I + D ES
Sbjct: 2584 VILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVKVLASDADEGSNADITYAI-EADS-ES 2641
Query: 316 FEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVT---VKI 372
+ + GVI K+ + ++ V A + + P K++V VKI
Sbjct: 2642 VKENLEINKLSGVITTKESLIGLENEFFTFFVRAVD--------NGSPSKESVVLVYVKI 2693
Query: 373 SVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFT 432
+ + P F P Y V E+ GT + + A+ + ++ D F
Sbjct: 2694 LPPEM-QLPKFSEPFYTFTVSEDVPIGTEIDLIRAEHSGTVLYSLVKGNTPESNRDESFV 2752
Query: 433 INPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQ-EAKVPVAIRVLDVNDNAPKF-AA 490
I+ + G +K K LD E T W ++ A + H+ A V V+I+V D NDN+P F ++
Sbjct: 2753 IDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFESS 2812
Query: 491 PYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPP----EIIHNPNFTVRDN 546
PYE FI E+ ++ I A D D NG + ++SL E+I +F +
Sbjct: 2813 PYEAFIVENLP----GGSRVIQIRASDADSGTNG-QVMYSLDQSQSVEVIE--SFAI--- 2862
Query: 547 RDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNA 606
+ G +K+D Y + +V SD G + ++T + V DVN + A
Sbjct: 2863 -NMETGWITTLKELDHEKRDNYQIKVVASDHG-EKIQLSSTAIVDVTVTDVNDSPPRFTA 2920
Query: 607 EAY--ILNAGLSTGALIAILA 625
E Y ++ G +IAIL+
Sbjct: 2921 EIYKGTVSEDDPQGGVIAILS 2941
Score = 127 bits (318), Expect = 5e-29
Identities = 146/562 (25%), Positives = 244/562 (43%), Gaps = 56/562 (9%)
Query: 80 DIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHAT-KTLDREERAQYTLMAQAVDRDTNRP 138
D S D + I SG G F I K+G I T + LDRE++ ++ L D + P
Sbjct: 1167 DSSSNDKLMYKITSGNPQG-FFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSP-P 1224
Query: 139 LEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTS-------VIQVTASDADDPTY 191
+ IVK+ D NDN P+FL + Y +PER + V A+D D+
Sbjct: 1225 KSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDE--- 1281
Query: 192 GNSAKLVYSILEGQPY--FSVEAQTGIIRTALPNMDREAKEEYHVV-IQAKDMGGHMGGL 248
G +A++ YSI +G + F +E +TG++ + A EY ++ I+A D G
Sbjct: 1282 GPNAEISYSIEDGNEHGKFFIEPKTGVV----SSKRFSAAGEYDILSIKAVDNGRPQ--K 1335
Query: 249 SGTTKV---TITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTY 305
S TT++ I+ + P F +S + +V E+ +G + + P I + +
Sbjct: 1336 SSTTRLHIEWISKPKPSLEPISFEESFFTFTVMESDPVAHMIGVISVEPPGIP----LWF 1391
Query: 306 NIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFK 365
+I G +++ D + G I + KP+D E K Y+L VEA +
Sbjct: 1392 DITGG----NYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATD--------GTTTIL 1439
Query: 366 DTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSIDRHT 425
V +K+ ++ D P F Y + E+ A T + ++ A D D N I Y++
Sbjct: 1440 TQVFIKV-IDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEKNKLI-YTLQSSR 1497
Query: 426 D--LDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVND 483
D + F ++P G + T++ LD E +TV + + + + V D ND
Sbjct: 1498 DPLSLKKFRLDPATGSLYTSEKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNVSDTND 1557
Query: 484 NAPKF-AAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNFT 542
+AP F A+ Y+G + ES ++ ++A DKD N ++S+ I N +F
Sbjct: 1558 HAPWFTASSYKGRVYESAAV----GSVVLQVTALDKDKGKNA-EVLYSIESGNIGN-SFM 1611
Query: 543 VRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALL 602
+ D G R Q Y L + +D G PPMS ++ I V D
Sbjct: 1612 I----DPVLGSIKTAKELDRSNQAEYDLMVKATDKGSPPMSEITSVRIFVTIADNASPKF 1667
Query: 603 SCNAEAYILNAGLSTGALIAIL 624
+ + L+ +S G+ + ++
Sbjct: 1668 TSKEYSVELSETVSIGSFVGMV 1689
Score = 113 bits (282), Expect = 8e-25
Identities = 116/429 (27%), Positives = 199/429 (46%), Gaps = 37/429 (8%)
Query: 103 IDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHE 162
I K GN T L+RE + YTL+ +A++++TN +E ++ V+V D ND P F
Sbjct: 98 IRTKGGN---TAILNREVKDHYTLIVKALEKNTN--VEARTKVRVQVLDTNDLRPLFSPT 152
Query: 163 TYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALP 222
+Y ++PE + + TS+ +V+A+DAD G + + YS + F++ +G+I
Sbjct: 153 SYSVSLPENTAIRTSIARVSATDAD---IGTNGEFYYSFKDRTDMFAIHPTSGVI-VLTG 208
Query: 223 NMDREAKEEYHVVIQAKDMGGHM---GGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSE 279
+D + Y + I A D G + G+S K+T+ + N+ P + +S SE
Sbjct: 209 RLDYLETKLYEMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVI--TAVTLSPSE 266
Query: 280 A-AVPGEEVGRVKAKDPDIGENG-LVTYNIVDGDGMESFEITTDYE-TQEGVIKLKKPVD 336
P + V D D G NG + + +IV GD ++ F + ++E +K +D
Sbjct: 267 LDRDPAYAI--VTVDDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGGID 324
Query: 337 FETKR-AYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQEN 395
+++ Y+L ++A + P+F S T S + P F Y E+ E
Sbjct: 325 WDSHPFGYNLTLQAKDKGTPPQFSSVKVIHVT-----SPQFKAGPVKFEKDVYRAEISEF 379
Query: 396 AAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLN 455
A T V V A A S +RY + + T F++N G I +P+ R++ A
Sbjct: 380 APPNTPVVMVKA---IPAYSHLRY-VFKSTPGKAKFSLNYNTGLISILEPVKRQQAAH-- 433
Query: 456 ITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISA 515
F E+ ++A V ++VL N N P+F + D+ P+ ++++SA
Sbjct: 434 ---FELEVTTSDRKASTKVLVKVLGANSNPPEFT--QTAYKAAFDENVPIGT-TVMSLSA 487
Query: 516 DDKDDTANG 524
D D+ NG
Sbjct: 488 VDPDEGENG 496
Score = 107 bits (268), Expect = 3e-23
Identities = 140/547 (25%), Positives = 221/547 (40%), Gaps = 53/547 (9%)
Query: 62 VIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREER 121
++ Y G + V +D S + Y ++ G F +D K+G + T R
Sbjct: 1889 LLPTYKGVKVITVNATDAD-SSAFSQLIYSITEGNIGEKFSMDYKTGALTVQNTTQLRSR 1947
Query: 122 AQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQV 181
+ T+ A ++ + + V++ ++ +F + Y A V E S ++ +
Sbjct: 1948 YELTVRA------SDGRFAGLTSVKINVKESKESHLKFTQDVYSAVVKENSTEAETLAVI 2001
Query: 182 TASDADDPTYGN--SAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAK 239
TA GN + L Y IL F + +G++ T DRE +E + VV++
Sbjct: 2002 TA-------IGNPINEPLFYHILNPDRRFKISRTSGVLSTTGTPFDREQQEAFDVVVEVT 2054
Query: 240 DMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGE 299
+ H V + + D NDN P F Y V G + V A D D G
Sbjct: 2055 EE--HKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGR 2112
Query: 300 NGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFET-KRAYSLKVEAANVHIDPKF 358
NG V Y + + E F+I G I LKK + +T + Y + V A K
Sbjct: 2113 NGEVHYYLKEHH--EHFQIGP-----LGEISLKKQFELDTLNKEYLVTVVA-------KD 2158
Query: 359 ISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIR 418
N F V V I+V + P+F P Y E+ E+ + V V A P+ +
Sbjct: 2159 GGNPAFSAEVIVPITVMNK-AMPVFEKPFYSAEIAESIQVHSPVVHVQANSPEGLK--VF 2215
Query: 419 YSIDRHTDLDRF--FTINPEDGFIKTTKPLDREETAWLNITVFAAE-IHNRHQEAKVPVA 475
YSI TD D F FTIN G I PLD E +++ A + + H A+V V
Sbjct: 2216 YSI---TDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAH--AEVFVD 2270
Query: 476 IRVLDVNDNAPKFA-APYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPE 534
I V D+NDN P FA Y + E+ + +V + A D D N
Sbjct: 2271 IIVDDINDNPPVFAQQSYAVTLSEAS----VIGTSVVQVRATDSDSEPNRGISYQMFGNH 2326
Query: 535 IIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCG 594
+ +F V D++ G+ + ++ + + + DGG+P +SS +T+ V
Sbjct: 2327 SKSHDHFHV----DSSTGLISLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDVTD 2382
Query: 595 CDVNGAL 601
+ N L
Sbjct: 2383 LNDNPPL 2389
Score = 97.4 bits (241), Expect = 4e-20
Identities = 124/520 (23%), Positives = 203/520 (39%), Gaps = 78/520 (15%)
Query: 124 YTLMAQAVDRDTNRPLEPPSEFIVKVQDIND-----NPPEFLHETYHANVPERSNVGTSV 178
Y L QA D+ T PP VKV + P +F + Y A + E + T V
Sbjct: 332 YNLTLQAKDKGT-----PPQFSSVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPV 386
Query: 179 IQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQA 238
+ V A P Y + + V+ G+ FS+ TG+I P + R+ + + +
Sbjct: 387 VMVKAI----PAYSH-LRYVFKSTPGKAKFSLNYNTGLISILEP-VKRQQAAHFELEVTT 440
Query: 239 KDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIG 298
D +TKV + + N NPP+F Q+ Y+ + E G V + A DPD G
Sbjct: 441 SDR-------KASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDEG 493
Query: 299 ENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFE-TKRAYSLKVEAANVHIDPK 357
ENG VTY+I + + D+ T G + + +D+E R Y+L++ A++ +
Sbjct: 494 ENGYVTYSIAN---LNHVPFAIDHFT--GAVSTSENLDYELMPRVYTLRIRASDWGL--- 545
Query: 358 FISNGPFKDTVTVKISV---EDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAAN 414
P++ V V ++ D P+F + + + G + V A D D
Sbjct: 546 -----PYRREVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADELQ 600
Query: 415 SPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLD---REETAWLNITVFAAEIHNRHQEAK 471
++Y I+ +LD FF++NP G + + L + ++ ++ + A + N
Sbjct: 601 L-VQYQIEAGNELD-FFSLNPNSGVLSLKRSLMDGLGAKVSFHSLRITATDGENFATPLY 658
Query: 472 VPVAIRVLDVNDNAPKFAAPYEGFICES-DQTKPLSNQ-PIVTISADDKDDTANGPRFIF 529
+ + + N + E Q L NQ + I D A+ P+F
Sbjct: 659 INITVAASHKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFDSHSVNAHIPQFRS 718
Query: 530 SLPPEI-----------IHNPNFTVRDNRDNTAGVYARRGG------------------- 559
+LP I + N T D N VYA GG
Sbjct: 719 TLPTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGGNEDSCFMIDMETGMLKILS 778
Query: 560 -FSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVN 598
R+ D Y L I + D GIP ++ L + V + N
Sbjct: 779 PLDRETTDKYTLNITVYDLGIPQKAAWRLLHVVVVDANDN 818
Score = 63.2 bits (152), Expect = 9e-10
Identities = 59/239 (24%), Positives = 101/239 (42%), Gaps = 20/239 (8%)
Query: 150 QDINDNPPEFLHETYHANVPERSNVGTSVIQVTASDA--DDPTYGNSAKLVY----SILE 203
Q + P +F H Y+ V E S T V P + K+V ++ +
Sbjct: 25 QRLEQTPLQFTHLEYNVTVQENSAAKTYVGHPVKMGVYITHPAWEVRYKIVSGDSENLFK 84
Query: 204 GQPYFSVEAQTGIIRTALPN---MDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTD 260
+ Y + IRT N ++RE K+ Y ++++A + ++ TKV + + D
Sbjct: 85 AEEYILGDFCFLRIRTKGGNTAILNREVKDHYTLIVKALEKNTNV---EARTKVRVQVLD 141
Query: 261 VNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITT 320
ND P F + Y +S+ E + RV A D DIG NG Y+ D M + T+
Sbjct: 142 TNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRTDMFAIHPTS 201
Query: 321 DYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADE 379
GVI L +D+ + Y +++ AA+ + K + + + +E A+E
Sbjct: 202 ------GVIVLTGRLDYLETKLYEMEILAADRGM--KLYGSSGISSMAKLTVHIEQANE 252
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 205 bits (522), Expect = 1e-52
Identities = 187/668 (27%), Positives = 308/668 (46%), Gaps = 79/668 (11%)
Query: 41 KGKEGQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGA--- 97
K K Q L+RSKR WV + EE GP P L+G L +++ S + ++ Y++SG G
Sbjct: 42 KEKIYQPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNM-SYNMSLMYLISGPGVDEY 100
Query: 98 ---GTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDIND 154
G + D ++G I+ + +DRE +T+ V+R T + ++ F +++ D+ND
Sbjct: 101 PEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVND 160
Query: 155 NPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSI----LEGQPYFSV 210
+ P+F + ++ V E + G + Q+ A D D+ NS L + I L + F V
Sbjct: 161 HAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKESGFRV 220
Query: 211 EAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQ 270
+ +G IR + +D E ++ ++I+A+D G LS TT V + + + N++ P F Q
Sbjct: 221 DRLSGEIRLS-GCLDYETAPQFTLLIRARDCG--EPSLSSTTTVHVDVQEGNNHRPAFTQ 277
Query: 271 SVYQMSVSEA-AVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVI 329
Y++ + E A G V+ +D +NI+ G+ F+I+TD ET EG++
Sbjct: 278 ENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGIL 337
Query: 330 KLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKD------TVTVKISVEDADEPPMF 383
+ KP+D+ET+ A SL + N F G + + TV + V DA++PP F
Sbjct: 338 NVIKPLDYETRPAQSLIIVVENEE-RLVFCERGKLQPPRKAAASATVSVQVTDANDPPAF 396
Query: 384 LAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTT 443
S+I +E A GT++G +A DPD S IRY + D + +++ G + T
Sbjct: 397 HPQSFIVNKEEGARPGTLLGTFNAMDPD---SQIRYELVH--DPANWVSVDKNSGVVITV 451
Query: 444 KPLDRE----ETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGF--IC 497
+P+DRE ++ I + A + Q A + + + D+NDN P P + +C
Sbjct: 452 EPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTL-RPRSRYMEVC 510
Query: 498 ESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAG----- 552
ES +PL I A+D D F F L DNT G
Sbjct: 511 ESAVHEPLH------IEAEDPDLEPFSDPFTFEL----------------DNTWGNAEDT 548
Query: 553 -VYARRGGFSRQKQDL-------YLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSC 604
R G S + L YL+P+ I D +S T+ +++C C + L+C
Sbjct: 549 WKLGRNWGQSVELLTLRSLPRGNYLVPLFIGDK--QGLSQKQTVHVRICPC---ASGLTC 603
Query: 605 NAEAYILNAGLSTGALIAILACIVILLVIVVLFVT---LRRQKKEPLIVFEEEDVRENII 661
E GL GAL + A V L V ++ + + K+ V +E + ++
Sbjct: 604 -VELADAEVGLHVGALFPVCAAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEG-HQTLV 661
Query: 662 TYDDEGGG 669
Y+ E G
Sbjct: 662 MYNAESKG 669
>gi|221316595 cadherin 17 precursor [Homo sapiens]
Length = 832
Score = 204 bits (520), Expect = 2e-52
Identities = 172/598 (28%), Positives = 274/598 (45%), Gaps = 45/598 (7%)
Query: 62 VIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVID-DKSGNIHATKTLDREE 120
++E T P P+ + + + D +Y L + F D+ G+I+ T+ LDREE
Sbjct: 247 MVENSTDPHPIKI----TQVRWNDPGAQYSLVDKEKLPRFPFSIDQEGDIYVTQPLDREE 302
Query: 121 RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ 180
+ Y A A D + +PL P E VKV+DINDNPP V E +G S+
Sbjct: 303 KDAYVFYAVAKD-EYGKPLSYPLEIHVKVKDINDNPPTCPSPVTVFEVQENERLGNSIGT 361
Query: 181 VTASDADDPTYGNSAKLVYSILEGQP------YFSVEAQTGIIRTALPNMDREAKEEYHV 234
+TA D D+ NS L Y I+E P F ++ G+++ A ++ ++ +Y++
Sbjct: 362 LTAHDRDEENTANSF-LNYRIVEQTPKLPMDGLFLIQTYAGMLQLAKQSLKKQDTPQYNL 420
Query: 235 VIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVY-QMSVSEAAVPGEEVGRVKAK 293
I+ D V I + D+ND P F +S Y ++++E G + ++A
Sbjct: 421 TIEVSDKD-----FKTLCFVQINVIDINDQIPIFEKSDYGNLTLAEDTNIGSTILTIQAT 475
Query: 294 DPDIGENGL--VTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAAN 351
D D G + Y+I+ GD + TD T G + +KKP+DFET ++ +A N
Sbjct: 476 DADEPFTGSSKILYHIIKGDSEGRLGVDTDPHTNTGYVIIKKPLDFETAAVSNIVFKAEN 535
Query: 352 VH---IDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAK 408
K+ ++ K T+ V D +E P F + +V E+ A GT VG V AK
Sbjct: 536 PEPLVFGVKYNASSFAKFTLIVT----DVNEAPQFSQHVFQAKVSEDVAIGTKVGNVTAK 591
Query: 409 DPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQ 468
DP+ + I YS+ D + I+ G I + PLDRE + + V A E+
Sbjct: 592 DPEGLD--ISYSL--RGDTRGWLKIDHVTGEIFSVAPLDREAGSPYRVQVVATEVGGSSL 647
Query: 469 EAKVPVAIRVLDVNDNAPKFAAPYEG-FICESDQTKPLSNQPIVTISADDKDDTA-NGPR 526
+ + ++DVNDN P+ A Y G F C PLS + A D D GP
Sbjct: 648 SSVSEFHLILMDVNDNPPRLAKDYTGLFFCH-----PLSAPGSLIFEATDDDQHLFRGPH 702
Query: 527 FIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTN 586
F FSL + N ++ V A + R F ++ Y++ I I+DGG PP+
Sbjct: 703 FTFSLGSGSLQN-DWEVSKINGTHARLSTRHTEFEERE---YVVLIRINDGGRPPLEGIV 758
Query: 587 TLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQK 644
+L + C C + I G++ G L+ L +VI +++ V+F+ +++ K
Sbjct: 759 SLPVTFCSCVEGSCFRPAGHQTGIPTVGMAVGILLTTL--LVIGIILAVVFIRIKKDK 814
Score = 154 bits (390), Expect = 2e-37
Identities = 138/455 (30%), Positives = 211/455 (46%), Gaps = 47/455 (10%)
Query: 88 IKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIV 147
+ + L+GE IFVI+ + G ++ + LDRE R+ + L A+D + +E P +
Sbjct: 58 VTFELTGE-TDNIFVIE-REGLLYYNRALDRETRSTHNLQVAALDAN-GIIVEGPVPITI 114
Query: 148 KVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP- 206
KV+DINDN P FL Y +V + S G + V A+D DDP N +L Y I+ P
Sbjct: 115 KVKDINDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPN-GQLYYQIVIQLPM 173
Query: 207 -----YFSVEAQTGII---RTALPNMDREAKEEYHVVIQAKDMGGHM-GGLSGTTKVTIT 257
YF + +TG I R ++ Y++VI KDMGG S TT V I
Sbjct: 174 INNVMYFQINNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDII 233
Query: 258 LTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFE 317
+T +N K P+ V + S P ++ +V+ DP Y++VD + + F
Sbjct: 234 VT---ENIWKAPKPVEMVENSTDPHP-IKITQVRWNDPG------AQYSLVDKEKLPRFP 283
Query: 318 ITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDA 377
+ D QEG I + +P+D E K AY A + + P + + + V+D
Sbjct: 284 FSID---QEGDIYVTQPLDREEKDAYVFYAVAKDEY-------GKPLSYPLEIHVKVKDI 333
Query: 378 -DEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPD---AANSPIRYSIDRHT---DLDRF 430
D PP +P + EVQEN G +G + A D D ANS + Y I T +D
Sbjct: 334 NDNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGL 393
Query: 431 FTINPEDGFIKTTK-PLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFA 489
F I G ++ K L +++T N+T+ E+ ++ + V I V+D+ND P F
Sbjct: 394 FLIQTYAGMLQLAKQSLKKQDTPQYNLTI---EVSDKDFKTLCFVQINVIDINDQIPIFE 450
Query: 490 APYEGFICESDQTKPLSNQPIVTISADDKDDTANG 524
G + ++ T I+TI A D D+ G
Sbjct: 451 KSDYGNLTLAEDTN--IGSTILTIQATDADEPFTG 483
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,567,487
Number of Sequences: 37866
Number of extensions: 1586299
Number of successful extensions: 9162
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 197
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3593
Number of HSP's gapped (non-prelim): 885
length of query: 796
length of database: 18,247,518
effective HSP length: 110
effective length of query: 686
effective length of database: 14,082,258
effective search space: 9660428988
effective search space used: 9660428988
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.