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Search of human proteins with 16306530
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
(788 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 1581 0.0
gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] 1186 0.0
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 1145 0.0
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 987 0.0
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 957 0.0
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 957 0.0
gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 943 0.0
gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens] 932 0.0
gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 924 0.0
gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] 920 0.0
gi|16753221 cadherin 22 precursor [Homo sapiens] 801 0.0
gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens] 757 0.0
gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens] 738 0.0
gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens] 713 0.0
gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens] 530 e-150
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 429 e-120
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 422 e-118
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 389 e-108
gi|4826669 cadherin 15 preproprotein [Homo sapiens] 362 e-99
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 350 2e-96
gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 252 1e-66
gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 252 1e-66
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 247 3e-65
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 243 7e-64
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 233 7e-61
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 233 7e-61
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 225 1e-58
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 209 6e-54
gi|221316595 cadherin 17 precursor [Homo sapiens] 207 3e-53
gi|221316593 cadherin 17 precursor [Homo sapiens] 207 3e-53
>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
Length = 788
Score = 1581 bits (4094), Expect = 0.0
Identities = 788/788 (100%), Positives = 788/788 (100%)
Query: 1 MTIHQFLLLFLFWVCLPHFCSPEIMFRRTPVPQQRILSSRVPRSDGKILHRQKRGWMWNQ 60
MTIHQFLLLFLFWVCLPHFCSPEIMFRRTPVPQQRILSSRVPRSDGKILHRQKRGWMWNQ
Sbjct: 1 MTIHQFLLLFLFWVCLPHFCSPEIMFRRTPVPQQRILSSRVPRSDGKILHRQKRGWMWNQ 60
Query: 61 FFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDRE 120
FFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDRE
Sbjct: 61 FFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDRE 120
Query: 121 EKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVV 180
EKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVV
Sbjct: 121 EKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVV 180
Query: 181 QVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAK 240
QVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAK
Sbjct: 181 QVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAK 240
Query: 241 DMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGK 300
DMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGK
Sbjct: 241 DMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGK 300
Query: 301 NAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFY 360
NAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFY
Sbjct: 301 NAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFY 360
Query: 361 YLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRF 420
YLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRF
Sbjct: 361 YLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRF 420
Query: 421 SLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRIL 480
SLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRIL
Sbjct: 421 SLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRIL 480
Query: 481 DVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDN 540
DVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDN
Sbjct: 481 DVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDN 540
Query: 541 EDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSA 600
EDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSA
Sbjct: 541 EDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSA 600
Query: 601 EALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDE 660
EALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDE
Sbjct: 601 EALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDE 660
Query: 661 GGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNTDVRDFINERLKE 720
GGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNTDVRDFINERLKE
Sbjct: 661 GGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNTDVRDFINERLKE 720
Query: 721 HDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYG 780
HDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYG
Sbjct: 721 HDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYG 780
Query: 781 GGESDKDS 788
GGESDKDS
Sbjct: 781 GGESDKDS 788
>gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 1186 bits (3068), Expect = 0.0
Identities = 577/791 (72%), Positives = 678/791 (85%), Gaps = 4/791 (0%)
Query: 1 MTIHQFLLLFLFWVCLPHFCSPEIMFRRTPVPQQRILSSRVPRSDGKILHRQKRGWMWNQ 60
M +++ LL LFWV P+ + +RT + + + + L+R KR WMWNQ
Sbjct: 1 MRTYRYFLL-LFWVGQPYPTLSTPLSKRTSGFPAKKRALELSGNSKNELNRSKRSWMWNQ 59
Query: 61 FFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDRE 120
FFLLEEYTGSDYQYVGKLHSDQD+GDGSLKYILSGDGAG LFII+E TGDI AT+R+DRE
Sbjct: 60 FFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGDLFIINENTGDIQATKRLDRE 119
Query: 121 EKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVV 180
EK Y LRAQAINRRT RPVEPESEF+IKIHDINDNEP F +E+YTA+VPEMS VGT VV
Sbjct: 120 EKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTKEVYTATVPEMSDVGTFVV 179
Query: 181 QVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAK 240
QVTATDADDP+YGNSA+V+YSILQGQPYFSVE ETGII+TAL NM+RENREQYQVVIQAK
Sbjct: 180 QVTATDADDPTYGNSAKVVYSILQGQPYFSVESETGIIKTALLNMDRENREQYQVVIQAK 239
Query: 241 DMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGK 300
DMGGQMGGLSGTTTVNITLTDVNDNPPRFPQ+T + ESSP GT IG +KA+DAD G+
Sbjct: 240 DMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFKTPESSPPGTPIGRIKASDADVGE 299
Query: 301 NAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFY 360
NAE+EY I DG+G DMFD++T+++TQEGIITVKK LD+E +++YTLKVEA N +V+PRF
Sbjct: 300 NAEIEYSITDGEGLDMFDVITDQETQEGIITVKKLLDFEKKKVYTLKVEASNPYVEPRFL 359
Query: 361 YLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRF 420
YLGPFKD+ V+I +EDVDEPPVFS+ +Y+ ++ ED ++ T IG+V A+DPD+ +P+++
Sbjct: 360 YLGPFKDSATVRIVVEDVDEPPVFSKLAYILQIREDAQINTTIGSVTAQDPDAARNPVKY 419
Query: 421 SLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRIL 480
S+DRHTD+DRIFNI SGNGS++TSK LDRE WHN+TVIA EINNPK+++RV +++++L
Sbjct: 420 SVDRHTDMDRIFNIDSGNGSIFTSKLLDRETLLWHNITVIATEINNPKQSSRVPLYIKVL 479
Query: 481 DVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSL---AAVNPNFTV 537
DVNDNAP+FA FY+TFVCE A+ QLIQT+ AVDKDDP G +F FSL AA NFT+
Sbjct: 480 DVNDNAPEFAEFYETFVCEKAKADQLIQTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTI 539
Query: 538 QDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQS 597
QDN+DNTA ILTRKNG+NRHE+STYLLPVVISDNDYP+QSSTGT+T+RVCACD GNMQS
Sbjct: 540 QDNKDNTAGILTRKNGYNRHEMSTYLLPVVISDNDYPVQSSTGTVTVRVCACDHHGNMQS 599
Query: 598 CSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSY 657
C AEAL+ P GLSTGAL+AILLCI+ILLV VVLFAAL+RQRKKEPLI+SKEDIRDNIVSY
Sbjct: 600 CHAEALIHPTGLSTGALVAILLCIVILLVTVVLFAALRRQRKKEPLIISKEDIRDNIVSY 659
Query: 658 NDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNTDVRDFINER 717
NDEGGGEEDTQAFDIGTLRNP AIE+ KLRRDI+PE LF+PRRTPTA DNTDVRDFIN+R
Sbjct: 660 NDEGGGEEDTQAFDIGTLRNPEAIEDNKLRRDIVPEALFLPRRTPTARDNTDVRDFINQR 719
Query: 718 LKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAE 777
LKE+D DPTAPPYDSLATYAYEG S+A+SLSSLES TT+ DQ+YDYL +WGPRF KLA+
Sbjct: 720 LKENDTDPTAPPYDSLATYAYEGTGSVADSLSSLESVTTDADQDYDYLSDWGPRFKKLAD 779
Query: 778 MYGGGESDKDS 788
MYGG +SDKDS
Sbjct: 780 MYGGVDSDKDS 790
>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
Length = 789
Score = 1145 bits (2963), Expect = 0.0
Identities = 549/793 (69%), Positives = 679/793 (85%), Gaps = 10/793 (1%)
Query: 1 MTIHQFLLLFLFWVCLPHFCSPEIMFRRTPVPQQRILSSRVP---RSDGKILHRQKRGWM 57
M + ++ LF+ W + H ++ + P + S ++ + DGK+L R KRGWM
Sbjct: 1 MRTYHYIPLFI-WTYMFHTVDTILLQEK---PNSYLSSKKIAGLTKDDGKMLRRTKRGWM 56
Query: 58 WNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRI 117
WNQFFLLEEYTG+D QYVGKLH+DQDKGDG+LKYIL+GDGAG+LF+IDE TGDIHA +++
Sbjct: 57 WNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGDIHAAKKL 116
Query: 118 DREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGT 177
DREEK+ Y LRA+AI+R+T R VEPESEF+IKIHDINDNEP F +++YTASVPEMS VGT
Sbjct: 117 DREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGT 176
Query: 178 SVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENREQYQVVI 237
SV+QVTATDADD +YGNSA+V+YSILQGQPYFSV+PE+GII+TALP+M+RENREQYQVVI
Sbjct: 177 SVIQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENREQYQVVI 236
Query: 238 QAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDAD 297
QAKDMGGQMGGLSGTTTVNITLTDVN+NPPRFPQ+T ES P+GT +G +KA D D
Sbjct: 237 QAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPD 296
Query: 298 TGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDP 357
G+NAE+EY I +GDG DMFD++T+KDTQEGIITVK+ LD+E++ LYTL+V+A NTH DP
Sbjct: 297 VGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDP 356
Query: 358 RFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSP 417
RF +LGPFKDT +VKIS+ED+DEPPVF++ SYL EV ED++ G+IIG V A DPD+ ++
Sbjct: 357 RFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNL 416
Query: 418 IRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFV 477
I++S+DRHTD+DRIF IHS NGS++T K LDRE S WHN+TV A EINNPK+++ + VF+
Sbjct: 417 IKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFI 476
Query: 478 RILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLA---AVNPN 534
RILD+ND+AP+FA++Y+TFVCENA+PGQLIQT+S +DKDDP G KFFF +NPN
Sbjct: 477 RILDINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPN 536
Query: 535 FTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGN 594
FT+ DN+DNTA I+TRK+G++R+++STYLLP++I DNDYPIQSSTGTLTIRVCACD+QGN
Sbjct: 537 FTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGN 596
Query: 595 MQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNI 654
MQSC+AEAL+L AGLSTGAL+AILLC++ILL++VVLFAALKRQRKKEPLI+SK+D+RDNI
Sbjct: 597 MQSCTAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISKDDVRDNI 656
Query: 655 VSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNTDVRDFI 714
V+YNDEGGGEEDTQAFDIGTLRNP A E+ KLRRD++PET+F RRT +N DV+DFI
Sbjct: 657 VTYNDEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIRRTVPLWENIDVQDFI 716
Query: 715 NERLKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNK 774
+ RLKE+D DP+APPYDSLATYAYEGNDSIA+SLSSLES T + +Q+YDYL +WGPRF K
Sbjct: 717 HRRLKENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYDYLSDWGPRFKK 776
Query: 775 LAEMYGGGESDKD 787
LA+MYGG +SD+D
Sbjct: 777 LADMYGGDDSDRD 789
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 987 bits (2552), Expect = 0.0
Identities = 481/765 (62%), Positives = 610/765 (79%), Gaps = 12/765 (1%)
Query: 30 PVPQQRILSSRVPRSD-----GKILH--RQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQ 82
P PQQ + + PR + G+ H R KRGW+WNQFF+LEEY GS+ QYVGKLHSD
Sbjct: 25 PQPQQTLATE--PRENVIHLPGQRSHFQRVKRGWVWNQFFVLEEYVGSEPQYVGKLHSDL 82
Query: 83 DKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEP 142
DKG+G++KY LSGDGAGT+F IDE TGDIHA R +DREEK FYTLRAQA++ T +P+EP
Sbjct: 83 DKGEGTVKYTLSGDGAGTVFTIDETTGDIHAIRSLDREEKPFYTLRAQAVDIETRKPLEP 142
Query: 143 ESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSI 202
ESEF+IK+ DINDNEP F + Y A+VPEMS VG V+QV ATDADDP+YGNSARV+YSI
Sbjct: 143 ESEFIIKVQDINDNEPKFLDGPYVATVPEMSPVGAYVLQVKATDADDPTYGNSARVVYSI 202
Query: 203 LQGQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDV 262
LQGQPYFS++P+TG+IRTALPNM+RE +EQYQV+IQAKDMGGQ+GGL+GTT VNITLTDV
Sbjct: 203 LQGQPYFSIDPKTGVIRTALPNMDREVKEQYQVLIQAKDMGGQLGGLAGTTIVNITLTDV 262
Query: 263 NDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTE 322
NDNPPRFP++ HL+V ESSP+G+AIG ++A D D G+NAE+EY I+ GDG ++FDIVT+
Sbjct: 263 NDNPPRFPKSIFHLKVPESSPIGSAIGRIRAVDPDFGQNAEIEYNIVPGDGGNLFDIVTD 322
Query: 323 KDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPP 382
+DTQEG+I +KKPLD+E+++ YT KVEA N H+D RF+ GPFKDT VKIS+ DVDEPP
Sbjct: 323 EDTQEGVIKLKKPLDFETKKAYTFKVEASNLHLDHRFHSAGPFKDTATVKISVLDVDEPP 382
Query: 383 VFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLY 442
VFS+ Y EV+ED VGTIIG V A+D D SS +R+ +D +D D F I G++
Sbjct: 383 VFSKPLYTMEVYEDTPVGTIIGAVTAQDLDVGSSAVRYFIDWKSDGDSYFTIDGNEGTIA 442
Query: 443 TSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENAR 502
T++ LDRE + +N ++IA++++NP T++V + + +LDVN+ P+ +V Y+T VCENA+
Sbjct: 443 TNELLDRESTAQYNFSIIASKVSNPLLTSKVNILINVLDVNEFPPEISVPYETAVCENAK 502
Query: 503 PGQLIQTISAVDKDDPLGGQKFFFSL---AAVNPNFTVQDNEDNTARILTRKNGFNRHEI 559
PGQ+IQ +SA D+D GQ+F F L AA+ PNFTV+D +NTA I TR+NG++R +
Sbjct: 503 PGQIIQIVSAADRDLSPAGQQFSFRLSPEAAIKPNFTVRDFRNNTAGIETRRNGYSRRQQ 562
Query: 560 STYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILL 619
Y LPVVI D+ YP+QSST T+TIRVC CDS G + SC+ EA+ LP GLSTGALIAILL
Sbjct: 563 ELYFLPVVIEDSSYPVQSSTNTMTIRVCRCDSDGTILSCNVEAIFLPVGLSTGALIAILL 622
Query: 620 CIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPA 679
CI+ILL IVVL+ AL+RQ+KK+ L+ SKEDIRDN++ Y+DEGGGEEDTQAFDIG LRNP
Sbjct: 623 CIVILLAIVVLYVALRRQKKKDTLMTSKEDIRDNVIHYDDEGGGEEDTQAFDIGALRNPK 682
Query: 680 AIEEKKLRRDIIPETLFIPRRTPTAPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYE 739
IEE K+RRDI P++L +PR+ P DNTD+RDFI++RL+E+D+DPTAPPYDSLATYAYE
Sbjct: 683 VIEENKIRRDIKPDSLCLPRQRPPMEDNTDIRDFIHQRLQENDVDPTAPPYDSLATYAYE 742
Query: 740 GNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGES 784
G+ S+AESLSS++S TTE DQ+YDYL +WGPRF LA+M+G ES
Sbjct: 743 GSGSVAESLSSIDSLTTEADQDYDYLTDWGPRFKVLADMFGEEES 787
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 957 bits (2474), Expect = 0.0
Identities = 476/738 (64%), Positives = 583/738 (78%), Gaps = 6/738 (0%)
Query: 51 RQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGD 110
R KR W+WNQFF+LEEY GSD YVGKLHSD DKGDGS+KYILSG+GA ++FIIDE TGD
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGD 103
Query: 111 IHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVP 170
IHAT+R+DREE+A+YTLRAQA++R T +PVEPESEFVIKI DINDNEP F + YTA VP
Sbjct: 104 IHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVP 163
Query: 171 EMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENR 230
EMS VGTSVVQVTATDADDP+YGNSARV+YSILQGQPYFSVEP+TG+I+TALPNM+RE +
Sbjct: 164 EMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAK 223
Query: 231 EQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGS 290
+QY +VIQAKDM GQ GGLSGTT+V +TLTDVNDNPPRFP+ + V ES PV + +
Sbjct: 224 DQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVAR 283
Query: 291 VKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEA 350
+KA DAD G NAE+EY+I+DGDG +F I +K+TQEGIIT++K LD+E++ YTL++EA
Sbjct: 284 IKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEA 343
Query: 351 ENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARD 410
N DPRF LGPF DTT VKI +EDVDEPPVFS Y EV E +VG IIGTV A D
Sbjct: 344 ANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHD 403
Query: 411 PDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKET 470
PDS +SP+R+S+DR+TDL+R FNI + +G + T+K LDRE + HN+TV+A E NP +
Sbjct: 404 PDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQV 463
Query: 471 TRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSL-- 528
R V + ILD+NDNAP+FA+ Y+T VCENA+PGQ+IQ ISAVDKD+P G +F+FSL
Sbjct: 464 GRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTT 523
Query: 529 -AAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVC 587
A N NF+++DN+DNTA ILTR+NGF R E S Y LP+ I D+ P SST TLTIRVC
Sbjct: 524 DATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVC 583
Query: 588 ACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSK 647
CD+ G Q+C+AEA +LPAGLSTGALIAIL C++ LLV+++L ++R RKKEPLI +
Sbjct: 584 DCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILLIVTMRR-RKKEPLIFDE 642
Query: 648 E-DIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRT-PTAP 705
E DIR+NIV Y+DEGGGEEDT+AFD+ LRN I + K RRD+ PE F+ R + P
Sbjct: 643 ERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNVIRDTKTRRDVTPEIQFLSRPAFKSIP 702
Query: 706 DNTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYL 765
DN R+FI ERLKE D+DP APPYDSL TYA+EGN S+AESLSSL+S ++ DQNYDYL
Sbjct: 703 DNVIFREFIWERLKEADVDPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYL 762
Query: 766 REWGPRFNKLAEMYGGGE 783
+WGPRF +LA+MYG G+
Sbjct: 763 SDWGPRFKRLADMYGTGQ 780
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 957 bits (2474), Expect = 0.0
Identities = 476/738 (64%), Positives = 583/738 (78%), Gaps = 6/738 (0%)
Query: 51 RQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGD 110
R KR W+WNQFF+LEEY GSD YVGKLHSD DKGDGS+KYILSG+GA ++FIIDE TGD
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGD 103
Query: 111 IHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVP 170
IHAT+R+DREE+A+YTLRAQA++R T +PVEPESEFVIKI DINDNEP F + YTA VP
Sbjct: 104 IHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVP 163
Query: 171 EMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENR 230
EMS VGTSVVQVTATDADDP+YGNSARV+YSILQGQPYFSVEP+TG+I+TALPNM+RE +
Sbjct: 164 EMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAK 223
Query: 231 EQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGS 290
+QY +VIQAKDM GQ GGLSGTT+V +TLTDVNDNPPRFP+ + V ES PV + +
Sbjct: 224 DQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVAR 283
Query: 291 VKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEA 350
+KA DAD G NAE+EY+I+DGDG +F I +K+TQEGIIT++K LD+E++ YTL++EA
Sbjct: 284 IKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEA 343
Query: 351 ENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARD 410
N DPRF LGPF DTT VKI +EDVDEPPVFS Y EV E +VG IIGTV A D
Sbjct: 344 ANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHD 403
Query: 411 PDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKET 470
PDS +SP+R+S+DR+TDL+R FNI + +G + T+K LDRE + HN+TV+A E NP +
Sbjct: 404 PDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQV 463
Query: 471 TRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSL-- 528
R V + ILD+NDNAP+FA+ Y+T VCENA+PGQ+IQ ISAVDKD+P G +F+FSL
Sbjct: 464 GRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTT 523
Query: 529 -AAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVC 587
A N NF+++DN+DNTA ILTR+NGF R E S Y LP+ I D+ P SST TLTIRVC
Sbjct: 524 DATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVC 583
Query: 588 ACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSK 647
CD+ G Q+C+AEA +LPAGLSTGALIAIL C++ LLV+++L ++R RKKEPLI +
Sbjct: 584 DCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILLIVTMRR-RKKEPLIFDE 642
Query: 648 E-DIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRT-PTAP 705
E DIR+NIV Y+DEGGGEEDT+AFD+ LRN I + K RRD+ PE F+ R + P
Sbjct: 643 ERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNVIRDTKTRRDVTPEIQFLSRPAFKSIP 702
Query: 706 DNTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYL 765
DN R+FI ERLKE D+DP APPYDSL TYA+EGN S+AESLSSL+S ++ DQNYDYL
Sbjct: 703 DNVIFREFIWERLKEADVDPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYL 762
Query: 766 REWGPRFNKLAEMYGGGE 783
+WGPRF +LA+MYG G+
Sbjct: 763 SDWGPRFKRLADMYGTGQ 780
>gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 943 bits (2437), Expect = 0.0
Identities = 461/744 (61%), Positives = 588/744 (79%), Gaps = 5/744 (0%)
Query: 47 KILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDE 106
++ HR KRGW+WNQFF+LEE+ G D QYVGKLHS+ DKGDGS+KYIL+G+GAGT+FIID+
Sbjct: 46 EVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDD 105
Query: 107 KTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYT 166
TGDIH+T+ +DRE+K Y L AQAI+RRT +P+EPESEF+IK+ DINDN P F + Y
Sbjct: 106 TTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYI 165
Query: 167 ASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMN 226
+VPEMS +GTSV+QVTATDADDP+YGNSARV+YSILQGQPYFSV+P+TG+IRTAL NM+
Sbjct: 166 VTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMD 225
Query: 227 RENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGT 286
RE RE Y VVIQAKDM GQ+GGLSG+TTVNITLTDVNDNPPRFPQ L V ES+ VG+
Sbjct: 226 REAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGS 285
Query: 287 AIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTL 346
A+G +KA DADTG NA++ Y II+GDG +F I T+K+T+EGI+++KKPL+YE ++ YTL
Sbjct: 286 AVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTL 345
Query: 347 KVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTV 406
+E NTH+D RF +LGPFKD T++KI + DVDEPP+FS SYL EV+E+ ++GT++GTV
Sbjct: 346 NIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTV 405
Query: 407 MARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINN 466
+A+DPDS +S +R+ ++ + + DR FNI + G++ T+K LDRE + W+N+TV A+EI+N
Sbjct: 406 LAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDN 465
Query: 467 PKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFF 526
P + V V +R+LDVNDN P+ A YD VCEN++PGQ+I TISA DKDD G +F F
Sbjct: 466 PDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFNF 525
Query: 527 SL---AAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLT 583
L VNPNFT++DNEDNTA ILTR+ F+R Y LP++ISD P SS+ TLT
Sbjct: 526 FLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLT 585
Query: 584 IRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPL 643
IRVCAC+ G +++C AEA L AGLSTGALIAILLC++ILL IVVLF L+R KKEPL
Sbjct: 586 IRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRS-KKEPL 644
Query: 644 ILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPR-RTP 702
I+S+ED+R+N+V+Y+DEGGGEEDT+AFDI LRNP+A EE K RRDI PE PR +T
Sbjct: 645 IISEEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQTS 704
Query: 703 TAPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNY 762
+ ++ DV++FI +RL E DLDP+ PPYDSL TYAYEG S A S+SSL+S TT+ DQ+Y
Sbjct: 705 STLESIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDY 764
Query: 763 DYLREWGPRFNKLAEMYGGGESDK 786
YL +WGP F KLAE+YG ES++
Sbjct: 765 HYLGDWGPEFKKLAELYGEIESER 788
>gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens]
Length = 799
Score = 932 bits (2410), Expect = 0.0
Identities = 461/790 (58%), Positives = 586/790 (74%), Gaps = 16/790 (2%)
Query: 9 LFLFWVCLPHFCSPEIMFRRTPVPQQRILSSRVPRS------DGKILHRQKRGWMWNQFF 62
L + W+ LP P I P+ Q ++L S P + +IL+R KRGW+WNQ F
Sbjct: 16 LIILWITLP----PCIYM--APMNQSQVLMSGSPLELNSLGEEQRILNRSKRGWVWNQMF 69
Query: 63 LLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEK 122
+LEE++G + VG+LH+D D G +KYILSGDGAGT+F I++ TGDIHA +R+DREEK
Sbjct: 70 VLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGTIFQINDVTGDIHAIKRLDREEK 129
Query: 123 AFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQV 182
A YTL AQA++ T +P+EP SEF+IK+ DINDN P F Y A+VPEMS++GTSV V
Sbjct: 130 AEYTLTAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNV 189
Query: 183 TATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDM 242
TATDADDP YGNSA+++YSIL+GQPYFS+EPET II+TALPNM+RE +E+Y VVIQAKDM
Sbjct: 190 TATDADDPVYGNSAKLVYSILEGQPYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDM 249
Query: 243 GGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNA 302
GG GGLSGTTT+ +TLTDVNDNPP+F Q+ H V E +GTAIG VKA D D G+NA
Sbjct: 250 GGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQDIGENA 309
Query: 303 EVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYL 362
+ Y IIDGDGT +F+I ++ Q+GII ++KPLD+E+++ YTLKVEA N H+DPRF
Sbjct: 310 QSSYDIIDGDGTALFEITSDAQAQDGIIRLRKPLDFETKKSYTLKVEAANVHIDPRFSGR 369
Query: 363 GPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSL 422
GPFKDT VKI +ED DEPPVFS +YL EVHE+ + ++IG V ARDPD SSPIRFS+
Sbjct: 370 GPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENAALNSVIGQVTARDPDITSSPIRFSI 429
Query: 423 DRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRILDV 482
DRHTDL+R FNI++ +G + + PLDRELS WHN+T+IA EI N + +RV V +++LDV
Sbjct: 430 DRHTDLERQFNINADDGKITLATPLDRELSVWHNITIIATEIRNHSQISRVPVAIKVLDV 489
Query: 483 NDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSL---AAVNPNFTVQD 539
NDNAP+FA Y+ F+CEN +PGQ+IQT+SA+DKDDP G F +SL NPNFT++
Sbjct: 490 NDNAPEFASEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKK 549
Query: 540 NEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCS 599
NEDN+ IL + NGFNR + YLLP++ISD+ P SST TLTIRVC C + G +QSC+
Sbjct: 550 NEDNSLSILAKHNGFNRQKQEVYLLPIIISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCN 609
Query: 600 AEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYND 659
EA +LP GLS GALIAIL CII+LLVIVVLF L+R + + +I ED+R+NI+ Y+D
Sbjct: 610 VEAYVLPIGLSMGALIAILACIILLLVIVVLFVTLRRHKNEPLIIKDDEDVRENIIRYDD 669
Query: 660 EGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRR-TPTAPDNTDVRDFINERL 718
EGGGEEDT+AFDI TL+NP I R+DI P+ F+PR+ P+ DV +FIN RL
Sbjct: 670 EGGGEEDTEAFDIATLQNPDGINGFLPRKDIKPDLQFMPRQGLAPVPNGVDVDEFINVRL 729
Query: 719 KEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEM 778
E D DPTAPPYDS+ Y YEG S+A SLSSLES T++ DQN+DYL +WGPRF +L E+
Sbjct: 730 HEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESTTSDSDQNFDYLSDWGPRFKRLGEL 789
Query: 779 YGGGESDKDS 788
Y GESDK++
Sbjct: 790 YSVGESDKET 799
>gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
Length = 796
Score = 924 bits (2387), Expect = 0.0
Identities = 452/753 (60%), Positives = 577/753 (76%), Gaps = 9/753 (1%)
Query: 45 DGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFII 104
+G++L R KRGW+WNQFF++EEYTG D VG+LHSD D GDG++KYILSG+GAGT+F+I
Sbjct: 44 EGQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVI 103
Query: 105 DEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEI 164
D+K+G+IHAT+ +DREE+A YTL AQA++R T RP+EP SEF++K+ DINDN P F E
Sbjct: 104 DDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHET 163
Query: 165 YTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPN 224
Y A+VPE S VGTSV+QVTA+DADDP+YGNSA+++YSIL+GQPYFSVE +TGIIRTALPN
Sbjct: 164 YHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPN 223
Query: 225 MNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPV 284
M+RE +E+Y VVIQAKDMGG MGGLSGTT V ITLTDVNDNPP+FPQ+ + V E++
Sbjct: 224 MDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVP 283
Query: 285 GTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLY 344
G +G VKA D D G+N V Y I+DGDG + F+I T+ +TQEG+I +KKP+D+E++R Y
Sbjct: 284 GEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAY 343
Query: 345 TLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIG 404
+LKVEA N H+DP+F GPFKDT VKIS+ED DEPP+F SY+ EV E+ GT++G
Sbjct: 344 SLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVG 403
Query: 405 TVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEI 464
V A+DPD+ +SPIR+S+DRHTDLDR F I+ +G + T+KPLDRE + W N+TV AAEI
Sbjct: 404 RVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEI 463
Query: 465 NNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENAR----PGQLIQTISAVDKDDPLG 520
+N + +V V +R+LDVNDNAP+FA Y+ F+CE+ + Q I TISA DKDD
Sbjct: 464 HNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTAN 523
Query: 521 GQKFFFSLAAV---NPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQS 577
G +F FSL NPNFTV+DN DNTA + R+ GF+R + YLLP+VISD P S
Sbjct: 524 GPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMS 583
Query: 578 STGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQ 637
ST TLTI+VC CD G + SC+AEA +L AGLSTGALIAIL CI+ILLVIVVLF L+RQ
Sbjct: 584 STNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQ 643
Query: 638 RKKEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFI 697
+K+ ++ +ED+R+NI++Y+DEGGGEEDT+AFDI TL+NP I R+DI PE ++
Sbjct: 644 KKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYM 703
Query: 698 PR-RTPTAPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTT 756
PR AP++ DV DFIN R++E D DPTAPPYDS+ Y YEG S+A SLSSLES TT
Sbjct: 704 PRPGLRPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATT 763
Query: 757 EGDQNYDYLREWGPRFNKLAEMYGGGES-DKDS 788
+ D +YDYL+ WGPRF KLA++YG ++ D DS
Sbjct: 764 DSDLDYDYLQNWGPRFKKLADLYGSKDTFDDDS 796
>gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens]
Length = 801
Score = 920 bits (2379), Expect = 0.0
Identities = 454/764 (59%), Positives = 584/764 (76%), Gaps = 13/764 (1%)
Query: 29 TPVPQQRI--LSSRVPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGD 86
TP PQ + L S P+S R KR W+WNQFF+LEEYTG+D YVGKLHSD D+GD
Sbjct: 36 TPTPQGELEALLSDKPQSH----QRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGD 91
Query: 87 GSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEF 146
GS+KYILSG+GAG +F ID+ TGDIHA +R+DREE+A YTLRAQA++RRT RP+EPESEF
Sbjct: 92 GSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEF 151
Query: 147 VIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQ 206
+IKI DINDNEP F + Y A+VPEMS VGTSV+QVTATDADDP+YGNSARV+YSILQGQ
Sbjct: 152 IIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQ 211
Query: 207 PYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNP 266
PYFSV+ +TG+IRTAL NM+RE +E Y+V+IQAKDMGGQ+GGL+GTTTVNITL+DVNDNP
Sbjct: 212 PYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNP 271
Query: 267 PRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQ 326
PRFPQ + VLES+P+ + +G V A D D G NAE++Y I+DGDG D FDI T+ + Q
Sbjct: 272 PRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQ 331
Query: 327 EGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSR 386
GIITVKKPL +ES++ YTLKVE N H++ RF LGPF+DTT V IS+EDVDEPPVF
Sbjct: 332 VGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEP 391
Query: 387 SSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKP 446
Y EV ED+ +GT I + A+DPD ++ IR+S+DR +D R F + G+L T++P
Sbjct: 392 GFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARP 451
Query: 447 LDRELSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQL 506
LDRE WHN+TV+A E+NNP + V V +++LDVNDNAP+F FY+ FVCENA+ GQL
Sbjct: 452 LDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQL 511
Query: 507 IQTISAVDKDDPLGGQKFFFSL---AAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYL 563
IQT+SAVD+DDP GQ F++SL AA NPNFT++DN+DNTARILTR++GF + E S +
Sbjct: 512 IQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFH 571
Query: 564 LPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIII 623
LP++I+D+ P+ SSTGTLTI+VC+CD G++ SCS EA +LP LS GALIAIL CI +
Sbjct: 572 LPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAILACIFV 631
Query: 624 LLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIE- 682
LLV+V+L +++R RK+ +I +E+I +NIV Y+DEGGGEEDT+AFDI + NP +
Sbjct: 632 LLVLVLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQA 691
Query: 683 --EKKLRRDIIPETLFIPRRTP-TAPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYE 739
K R+D++PE + R P T N+ V ++ +L E D+D APP+DSL TY +E
Sbjct: 692 GAAPKTRQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKLYEADMDLWAPPFDSLQTYMFE 751
Query: 740 GNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGE 783
G+ S+A SLSSL+S T++ +Q++D+L +WGPRF KLAE+YG E
Sbjct: 752 GDGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGASE 795
>gi|16753221 cadherin 22 precursor [Homo sapiens]
Length = 828
Score = 801 bits (2070), Expect = 0.0
Identities = 395/776 (50%), Positives = 550/776 (70%), Gaps = 30/776 (3%)
Query: 43 RSDGKI-LHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTL 101
R DG + R KRGW+WNQFF++EEYTG++ YVGK+HSD D+GDG++KY +SG+GAGT+
Sbjct: 50 RQDGALGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAGTI 109
Query: 102 FIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFP 161
F+IDE TGDIHA R+DRE+K FYTLRAQA +R T R +EPESEF+IK+ DIND+EP F
Sbjct: 110 FLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFL 169
Query: 162 EEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTA 221
Y SV E+S GTSV+QV A+DADDP+YG+SAR++YS+L G+ +F+V+P+TG+IRTA
Sbjct: 170 HGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTA 229
Query: 222 LPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLES 281
+P+++RE++E+Y+VVIQA DM GQ+GGLSG+TTV I +TDVNDNPPRFPQ + ES
Sbjct: 230 VPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQES 289
Query: 282 SPVGTAIGSVKATDADTGKNAEVEYRIID--GDGTDMFDIVTEKDTQEGIITVKKPLDYE 339
+P+GTA+G VKA D+D G+N ++ Y + D G D+F + T+ DTQE II V+K LD+E
Sbjct: 290 APIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFE 349
Query: 340 SRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEV 399
S+ ++T+ +EA N VDPRF LG F+D IV++++ DVDEPP F S L EV ED +V
Sbjct: 350 SQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQV 409
Query: 400 GTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTV 459
G+++G V ARDPD+ + P+R+++DR +DLD+IF+I + G++ T K LDRE + WHN+TV
Sbjct: 410 GSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETAGWHNITV 469
Query: 460 IAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPL 519
+A E +N + +R ++ +RILDVNDN P+ A Y+ VCE+A+PGQLIQTIS VD+D+P
Sbjct: 470 LAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQ 529
Query: 520 GGQKFFFSL---AAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQ 576
GG +F+F L A NP+F++ D +DNTA + T+ GFNR E + LP+++ D+ P
Sbjct: 530 GGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTL 589
Query: 577 SSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKR 636
SSTGTLTIR+C CDS G +QSC+ A ++ A LS GALIA+L+C++IL+V+V+L L+R
Sbjct: 590 SSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVLVLLILTLRR 649
Query: 637 QRKKEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKK----------- 685
K ED+RDN++ YNDEGGGE+DT+A+D+ LR+ E K
Sbjct: 650 HHKSHLSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDGGGSAGGG 709
Query: 686 ------------LRRDIIPETLFIPRRTPT-APDNTDVRDFINERLKEHDLDPTAPPYDS 732
+ + E +P+ P+ PD + RDFI+ ++ D D + PPYD+
Sbjct: 710 AGGGSGGGAGSPPQAHLPSERHSLPQGPPSPEPDFSVFRDFISRKVALADGDLSVPPYDA 769
Query: 733 LATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGESDKDS 788
TYA+EG DS A SLSSL SG++ +Q++ YL WGPRF LA +Y G D ++
Sbjct: 770 FQTYAFEGADSPAASLSSLHSGSSGSEQDFAYLSSWGPRFRPLAALYAGHRGDDEA 825
>gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens]
Length = 781
Score = 757 bits (1954), Expect = 0.0
Identities = 379/747 (50%), Positives = 522/747 (69%), Gaps = 14/747 (1%)
Query: 46 GKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIID 105
G L R +R W+WNQFF++EEY G + +GKLHSD D+G+G KY+L+G+GAGT+F+ID
Sbjct: 36 GPALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVID 95
Query: 106 EKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIY 165
E TG+IH T+ +DREEKA Y L AQA++R + RP+EP SEF+IK+ DINDN P FP Y
Sbjct: 96 EATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPY 155
Query: 166 TASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNM 225
A+VPEMS VGTSV+QVTA DADDPSYGNSA+++Y++L G P+FSV+P+TG++RTA+PNM
Sbjct: 156 HATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNM 215
Query: 226 NRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVG 285
+RE +E++ VVIQAKDMGG MGGLSG+TTV +TL+DVNDNPP+FPQ+ V+E++ G
Sbjct: 216 DRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPG 275
Query: 286 TAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYT 345
T +G ++A D D G NA + Y I+DG+G++ F I T+ ++G++TV+KPLD+ES+R Y+
Sbjct: 276 TLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYS 335
Query: 346 LKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGT 405
+VEA NT +DP + GPFKD V+++++D EPP F++++Y V E+ GT++G
Sbjct: 336 FRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQ 395
Query: 406 VMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEIN 465
+ A D DS +SPIR+S+ H+D +R F+I G+++T+ PLDRE WHNLTV+A E++
Sbjct: 396 ISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELD 455
Query: 466 NPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFF 525
+ + +RV V ++ LD NDNAPQ A YDTFVC++A PGQLIQ I A+D+D+ +G
Sbjct: 456 SSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDE-VGNSSHV 514
Query: 526 FSLAAVNP--NFTVQDNEDNTAR-ILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTL 582
+ P NFTVQDN D +A +L + RH + YL+P+ + D P SST T+
Sbjct: 515 SFQGPLGPDANFTVQDNRDGSASLLLPSRPAPPRH--APYLVPIELWDWGQPALSSTATV 572
Query: 583 TIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEP 642
T+ VC C G++ SC EA L AGLSTGAL+AI+ C+ LL +VVLF AL+RQ+++
Sbjct: 573 TVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEAL 632
Query: 643 LILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEE----KKLRRDIIPETLFIP 698
++L +ED+R+NI++Y+DEGGGEEDT+AFDI L+NP RRD++P
Sbjct: 633 MVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARRDVLPRARV-- 690
Query: 699 RRTPTAPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEG 758
R P P DV + RL+E D DP PPYDS+ Y YEG S SLSSL SG+ G
Sbjct: 691 SRQPRPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAG 750
Query: 759 DQ--NYDYLREWGPRFNKLAEMYGGGE 783
+ L +WGP F LAE+YG E
Sbjct: 751 GAPGPAEPLDDWGPLFRTLAELYGAKE 777
>gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens]
Length = 819
Score = 738 bits (1905), Expect = 0.0
Identities = 379/785 (48%), Positives = 522/785 (66%), Gaps = 52/785 (6%)
Query: 46 GKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIID 105
G L R +R W+WNQFF++EEY G + +GKLHSD D+G+G KY+L+G+GAGT+F+ID
Sbjct: 36 GPALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVID 95
Query: 106 EKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIY 165
E TG+IH T+ +DREEKA Y L AQA++R + RP+EP SEF+IK+ DINDN P FP Y
Sbjct: 96 EATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPY 155
Query: 166 TASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNM 225
A+VPEMS VGTSV+QVTA DADDPSYGNSA+++Y++L G P+FSV+P+TG++RTA+PNM
Sbjct: 156 HATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNM 215
Query: 226 NRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVG 285
+RE +E++ VVIQAKDMGG MGGLSG+TTV +TL+DVNDNPP+FPQ+ V+E++ G
Sbjct: 216 DRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPG 275
Query: 286 TAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYT 345
T +G ++A D D G NA + Y I+DG+G++ F I T+ ++G++TV+KPLD+ES+R Y+
Sbjct: 276 TLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYS 335
Query: 346 LKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGT 405
+VEA NT +DP + GPFKD V+++++D EPP F++++Y V E+ GT++G
Sbjct: 336 FRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQ 395
Query: 406 VMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEI- 464
+ A D DS +SPIR+S+ H+D +R F+I G+++T+ PLDRE WHNLTV+A E+
Sbjct: 396 ISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELG 455
Query: 465 -------------------------------------NNPKETTRVAVFVRILDVNDNAP 487
++ + +RV V ++ LD NDNAP
Sbjct: 456 WSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAP 515
Query: 488 QFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNP--NFTVQDNEDNTA 545
Q A YDTFVC++A PGQLIQ I A+D+D+ +G + P NFTVQDN D +A
Sbjct: 516 QLAEPYDTFVCDSAAPGQLIQVIRALDRDE-VGNSSHVSFQGPLGPDANFTVQDNRDGSA 574
Query: 546 R-ILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALL 604
+L + RH + YL+P+ + D P SST T+T+ VC C G++ SC EA L
Sbjct: 575 SLLLPSRPAPPRH--APYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHL 632
Query: 605 LPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGE 664
AGLSTGAL+AI+ C+ LL +VVLF AL+RQ+++ ++L +ED+R+NI++Y+DEGGGE
Sbjct: 633 SAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIITYDDEGGGE 692
Query: 665 EDTQAFDIGTLRNPAAIEE----KKLRRDIIPETLFIPRRTPTAPDNTDVRDFINERLKE 720
EDT+AFDI L+NP RRD++P R P P DV + RL+E
Sbjct: 693 EDTEAFDITALQNPDGAAPPAPGPPARRDVLPRARV--SRQPRPPGPADVAQLLALRLRE 750
Query: 721 HDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQ--NYDYLREWGPRFNKLAEM 778
D DP PPYDS+ Y YEG S SLSSL SG+ G + L +WGP F LAE+
Sbjct: 751 ADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAEL 810
Query: 779 YGGGE 783
YG E
Sbjct: 811 YGAKE 815
>gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens]
Length = 772
Score = 713 bits (1840), Expect = 0.0
Identities = 366/734 (49%), Positives = 511/734 (69%), Gaps = 12/734 (1%)
Query: 51 RQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGD 110
R KRGW+WNQFF+ EE + + ++G+L SD D G+ S +Y L G GAG+ FIIDE+TGD
Sbjct: 40 RVKRGWVWNQFFVPEEMNTTSH-HIGQLRSDLDNGNNSFQYKLLGAGAGSTFIIDERTGD 98
Query: 111 IHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVP 170
I+A +++DREE++ Y LRAQ I+ T R VEPESEFVIK+ DINDNEP F +E Y A VP
Sbjct: 99 IYAIQKLDREERSLYILRAQVIDIATGRAVEPESEFVIKVSDINDNEPKFLDEPYEAIVP 158
Query: 171 EMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENR 230
EMS GT V+QVTA+DADDPS GN+AR++YS+LQGQPYFSVEP TG+IR + M+RE +
Sbjct: 159 EMSPEGTLVIQVTASDADDPSSGNNARLLYSLLQGQPYFSVEPTTGVIRIS-SKMDRELQ 217
Query: 231 EQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGS 290
++Y V+IQAKDM GQ G LSGTT+V I L+DVNDN P F ++ L V ES+P GT+IG+
Sbjct: 218 DEYWVIIQAKDMIGQPGALSGTTSVLIKLSDVNDNKPIFKESLYRLTVSESAPTGTSIGT 277
Query: 291 VKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEA 350
+ A D D G+NAE++Y I+ D + FDI+T +TQEGI+ +KK +D+E + Y ++ +
Sbjct: 278 IMAYDNDIGENAEMDYS-IEEDDSQTFDIITNHETQEGIVILKKKVDFEHQNHYGIRAKV 336
Query: 351 ENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARD 410
+N HV + TT +KI +EDVDEPP+F Y+FEV E+ G+ +G V A D
Sbjct: 337 KNHHVPEQLMKYHTEASTTFIKIQVEDVDEPPLFLLPYYVFEVFEETPQGSFVGVVSATD 396
Query: 411 PDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKET 470
PD+ SPIR+S+ R ++FNI+ NG++ TS LDRE+S W+NL++ A E N ++
Sbjct: 397 PDNRKSPIRYSITR----SKVFNIND-NGTITTSNSLDREISAWYNLSITATEKYNIEQI 451
Query: 471 TRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAA 530
+ + ++V++L++ND+AP+F+ +Y+T+VCENA GQ+IQTISAVD+D+ + F+F+L+
Sbjct: 452 SSIPLYVQVLNINDHAPEFSQYYETYVCENAGSGQVIQTISAVDRDESIEEHHFYFNLSV 511
Query: 531 V---NPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVC 587
N +FT+ DN+DNTA ILT + GFN E + + ++I+DN P +ST TLTI VC
Sbjct: 512 EDTNNSSFTIIDNQDNTAVILTNRTGFNLQEEPVFYISILIADNGIPSLTSTNTLTIHVC 571
Query: 588 ACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSK 647
C G+ Q+C + L+L G T +IAIL+CI+I+ + L LK++RK+
Sbjct: 572 DCGDSGSTQTCQYQELVLSMGFKTEVIIAILICIMIIFGFIFLTLGLKQRRKQILFPEKS 631
Query: 648 EDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRT-PTAPD 706
ED R+NI Y+DEGGGEEDT+AFDI LR+ + E+K R+ E + R++ PD
Sbjct: 632 EDFRENIFQYDDEGGGEEDTEAFDIAELRSSTIMRERKTRKTTSAEIRSLYRQSLQVGPD 691
Query: 707 NTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLR 766
+ R FI E+L+E + DP APP+DSL TYA+EG S+A SLSSLES ++ D++YDYL
Sbjct: 692 SAIFRKFILEKLEEANTDPCAPPFDSLQTYAFEGTGSLAGSLSSLESAVSDQDESYDYLN 751
Query: 767 EWGPRFNKLAEMYG 780
E GPRF +LA M+G
Sbjct: 752 ELGPRFKRLACMFG 765
>gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens]
Length = 784
Score = 530 bits (1365), Expect = e-150
Identities = 314/761 (41%), Positives = 442/761 (58%), Gaps = 27/761 (3%)
Query: 32 PQQRILSSRVPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKY 91
P QR S +P RQKR W+WNQ + EE S +VGK+ S + + KY
Sbjct: 30 PAQRDTHSLLPTH-----RRQKRDWIWNQMHIDEEKNTSLPHHVGKIKSSVSRKNA--KY 82
Query: 92 ILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIH 151
+L G+ G +F +D +TGD+ A R+DRE + Y L A +++ T +E S F IK+H
Sbjct: 83 LLKGEYVGKVFRVDAETGDVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVH 142
Query: 152 DINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSV 211
D+NDN P F ++ ASVPE S VGTSV+ VTA DADDP+ G+ A V+Y IL+G+ YF++
Sbjct: 143 DVNDNWPVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKEYFAI 202
Query: 212 EPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQ 271
+ +G I T +++RE + +Y++V++A+D G + G SGT TV +TL D+NDN P F Q
Sbjct: 203 D-NSGRIITITKSLDREKQARYEIVVEARDAQG-LRGDSGTATVLVTLQDINDNFPFFTQ 260
Query: 272 NTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIIT 331
V E + VGT++GS+ D D +N +Y I+ GD D F I T EGII
Sbjct: 261 TKYTFVVPEDTRVGTSVGSLFVEDPDEPQNRMTKYSILRGDYQDAFTIETNPAHNEGIIK 320
Query: 332 VKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLF 391
KPLDYE + Y+ VEA + +D R Y P + V I+I DVDEPP+F + Y F
Sbjct: 321 PMKPLDYEYIQQYSFIVEATDPTIDLR-YMSPPAGNRAQVIINITDVDEPPIFQQPFYHF 379
Query: 392 EVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDREL 451
++ E+ + +IGTV+A DPD+ I +S+ R +D + F + + G +Y K LDRE+
Sbjct: 380 QLKEN-QKKPLIGTVLAMDPDAARHSIGYSIRRTSDKGQFFRV-TKKGDIYNEKELDREV 437
Query: 452 SQWHNLTVIAAEINNPKETTR----VAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLI 507
W+NLTV A E+++ T V V + +LD NDNAP+FA Y VCENA GQL+
Sbjct: 438 YPWYNLTVEAKELDSTGTPTGKESIVQVHIEVLDENDNAPEFAKPYQPKVCENAVHGQLV 497
Query: 508 QTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVV 567
ISA+DKD KF F L N NFT+ DN DNTA I + F+R + LPVV
Sbjct: 498 LQISAIDKDITPRNVKFKFILNTEN-NFTLTDNHDNTANITVKYGQFDREHTKVHFLPVV 556
Query: 568 ISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVI 627
ISDN P ++ T TLT+ VC C+ QG C E + G+S A++AILLCI+ + VI
Sbjct: 557 ISDNGMPSRTGTSTLTVAVCKCNEQGEFTFC--EDMAAQVGVSIQAVVAILLCILTITVI 614
Query: 628 VVLFAALKRQRKKEPLI-LSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEK-- 684
+L +R RK+ S +I + +V+Y++EGGGE DT ++D+ L + K
Sbjct: 615 TLLIFLRRRLRKQARAHGKSVPEIHEQLVTYDEEGGGEMDTTSYDVSVLNSVRRGGAKPP 674
Query: 685 ----KLRRDIIPETLFIPRRTPTAPDNT-DVRDFINERLKEHDLDPTAPPYDSLATYAYE 739
R + + PR P A ++ I + E D D PPYD+L Y YE
Sbjct: 675 RPALDARPSLYAQVQKPPRHAPGAHGGPGEMAAMIEVKKDEADHDGDGPPYDTLHIYGYE 734
Query: 740 GNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYG 780
G++SIAESLSSL + +++ D +YD+L +WGPRF LAE+YG
Sbjct: 735 GSESIAESLSSLGTDSSDSDVDYDFLNDWGPRFKMLAELYG 775
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 429 bits (1103), Expect = e-120
Identities = 290/771 (37%), Positives = 427/771 (55%), Gaps = 55/771 (7%)
Query: 49 LHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGT----LFII 104
L RQKR W+ L E G Q + ++ SD+DK + SL+Y ++G GA +FII
Sbjct: 154 LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDK-NLSLRYSVTGPGADQPPTGIFII 212
Query: 105 DEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEI 164
+ +G + T+ +DRE+ A + LRA A++ VE + VI + D+NDN P F ++
Sbjct: 213 NPISGQLSVTKPLDREQIARFHLRAHAVDING-NQVENPIDIVINVIDMNDNRPEFLHQV 271
Query: 165 YTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP------YFSVEPETGII 218
+ +VPE S GT V+ VTA DADDP+ N + Y I+ P F++ ETG I
Sbjct: 272 WNGTVPEGSKPGTYVMTVTAIDADDPNALNGM-LRYRIVSQAPSTPSPNMFTINNETGDI 330
Query: 219 RTALPNMNRENREQYQVVIQAKDM-GGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLR 277
T ++RE +QY ++IQA DM G GLS T T IT+TDVNDNPP F T +
Sbjct: 331 ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGE 390
Query: 278 VLESSPVGTAIGSVKATDADTGKNA--EVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKP 335
V E+ V + ++ TD D YRI GD T F I T+ ++ +G++TV KP
Sbjct: 391 VPENR-VDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKP 449
Query: 336 LDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHE 395
+D+E+ R++ L V AEN V P + T V +++ DV+E P F+ + + E
Sbjct: 450 IDFETNRMFVLTVAAEN-QVPLAKGIQHPPQSTATVSVTVIDVNENPYFAPNPKIIRQEE 508
Query: 396 DIEVGTIIGTVMARDPDS-ISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDREL--- 451
+ GT++ T A+DPD + IR++ + +D I NG + T LDRE
Sbjct: 509 GLHAGTMLTTFTAQDPDRYMQQNIRYT--KLSDPANWLKIDPVNGQITTIAVLDRESPNV 566
Query: 452 -SQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTI 510
+ +N T +A++ P + + + +LD+NDNAPQ + + CE P + I
Sbjct: 567 KNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQ-VLPQEAETCETPDPNSI--NI 623
Query: 511 SAVDKD-DPLGGQKFF---FSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPV 566
+A+D D DP G F S + N+T+ + A++ + E Y +P+
Sbjct: 624 TALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKFL---EAGIYEVPI 680
Query: 567 VISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLV 626
+I+D+ P +S+ L ++VC CDS G+ C+ ++ AGL TGA+IAILLCIIILL+
Sbjct: 681 IITDSGNPPKSNISILRVKVCQCDSNGD---CTDVDRIVGAGLGTGAIIAILLCIIILLI 737
Query: 627 IVVLFAALKRQRKKEP-----LILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAI 681
+V++F ++R KE LI ++D+RDNI+ Y++EGGGEED Q +D+ L+ P +
Sbjct: 738 LVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEED-QDYDLSQLQQPDTV 796
Query: 682 EEKKLR---------RDIIPETLFIPRRTPTAPDNTDVRDFINERLKEHDLDPTAPPYDS 732
E ++ R I E + R AP D+ DFINE LK D DPTAPPYDS
Sbjct: 797 EPDAIKPVGIRRMDERPIHAEPQYPVRSA--APHPGDIGDFINEGLKAADNDPTAPPYDS 854
Query: 733 LATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGE 783
L + YEG+ S A SLSSL S ++ G+Q+YDYL +WGPRF KLA+MYGGG+
Sbjct: 855 LLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGD 905
>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
Length = 916
Score = 422 bits (1084), Expect = e-118
Identities = 290/773 (37%), Positives = 420/773 (54%), Gaps = 56/773 (7%)
Query: 49 LHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGT----LFII 104
L R+KR W+ + E G Q + ++ SD+D D ++Y ++G GA +F I
Sbjct: 164 LRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVFSI 222
Query: 105 DEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEI 164
D +G ++ TR +DREE A Y LRA A++ + VE + I + D+NDN P F ++
Sbjct: 223 DSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNK-VENPIDLYIYVIDMNDNRPEFINQV 281
Query: 165 YTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPY------FSVEPETGII 218
Y SV E S GT V+ VTA DADD + N V Y I+ P F++ ETG I
Sbjct: 282 YNGSVDEGSKPGTYVMTVTANDADDSTTANGM-VRYRIVTQTPQSPSQNMFTINSETGDI 340
Query: 219 RTALPNMNRENREQYQVVIQAKDMGGQMG-GLSGTTTVNITLTDVNDNPPRFPQNTIHLR 277
T ++RE +QY V++QA DM G + GLS T T IT+TDVNDNPP F +T
Sbjct: 341 VTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGE 400
Query: 278 VLESSPVGTAIGSVKATDADT--GKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKP 335
V E+ V T + ++ D D N YRII GD + F + T+ T EG++TV K
Sbjct: 401 VPENR-VETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKA 459
Query: 336 LDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHE 395
+DYE R + L V N + F+ T V ISI D++E P F + L + E
Sbjct: 460 VDYELNRAFMLTVMVSNQAPLASGIQMS-FQSTAGVTISIMDINEAPYFPSNHKLIRLEE 518
Query: 396 DIEVGTIIGTVMARDPDS-ISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQW 454
+ GT++ T A DPD + +R+S + +D +I++ NG + T+ LDRE
Sbjct: 519 GVPPGTVLTTFSAVDPDRFMQQAVRYS--KLSDPASWLHINATNGQITTAAVLDRESLYT 576
Query: 455 HN----LTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTI 510
N T +AA+ P + + + ++D+NDNAP+ + +CE +P I
Sbjct: 577 KNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLP-KEAQICE--KPNLNAINI 633
Query: 511 SAVDKD-DPLGGQKFF---FSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPV 566
+A D D DP G F F AAV N+T+ + A++ R E Y +P+
Sbjct: 634 TAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLR---ILYLEAGMYDVPI 690
Query: 567 VISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLV 626
+++D+ P S+T + ++VC CD G+ C+ + AGL TGA++AIL+CI+ILL
Sbjct: 691 IVTDSGNPPLSNTSIIKVKVCPCDDNGD---CTTIGAVAAAGLGTGAIVAILICILILLT 747
Query: 627 IVVLFAALKRQRKKEP-----LILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAI 681
+V+LF ++R+KE LI ++D+RDNI+ Y++EGGGEED Q +D+ L+ P A+
Sbjct: 748 MVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEED-QDYDLSQLQQPEAM 806
Query: 682 EEKKLR---------RDIIPETLFIPRRTPTAPDNTDVRDFINERLKEHDLDPTAPPYDS 732
+ R + E + R P P D+ DFINE L+ D DPTAPPYDS
Sbjct: 807 GHVPSKAPGVRRVDERPVGAEPQYPIR--PMVPHPGDIGDFINEGLRAADNDPTAPPYDS 864
Query: 733 LATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGESD 785
L + YEG+ S A S+SSL S ++ GDQ+YDYL +WGPRF KLA+MYGGGE D
Sbjct: 865 LLVFDYEGSGSTAGSVSSLNS-SSSGDQDYDYLNDWGPRFKKLADMYGGGEED 916
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 389 bits (999), Expect = e-108
Identities = 270/759 (35%), Positives = 399/759 (52%), Gaps = 47/759 (6%)
Query: 49 LHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGT----LFII 104
L RQKR W+ E G + + ++ S++DK +G + Y ++G GA T +FII
Sbjct: 149 LRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDK-EGKVFYSITGQGADTPPVGVFII 207
Query: 105 DEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEI 164
+ +TG + T +DRE A YTL + A++ VE E +I + D NDN+P F +E+
Sbjct: 208 ERETGWLKVTEPLDRERIATYTLFSHAVSSNG-NAVEDPMEILITVTDQNDNKPEFTQEV 266
Query: 165 YTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP------YFSVEPETGII 218
+ SV E ++ GTSV++VTATDADD +A + Y+IL P F++ TG+I
Sbjct: 267 FKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVI 326
Query: 219 RTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRV 278
++RE+ Y +V+QA D+ G+ GLS T T IT+TD NDNPP F T +V
Sbjct: 327 SVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTATAVITVTDTNDNPPIFNPTTYKGQV 384
Query: 279 LESSPVGTAIGSVKATDADTGKNA--EVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPL 336
E+ I ++K TDAD E Y I++ DG F + T +GI+ K L
Sbjct: 385 PENE-ANVVITTLKVTDADAPNTPAWEAVYTILNDDG-GQFVVTTNPVNNDGILKTAKGL 442
Query: 337 DYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHED 396
D+E+++ Y L V T+V P + + T V + + DV+E P+F EV ED
Sbjct: 443 DFEAKQQYILHVAV--TNVVP--FEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSED 498
Query: 397 IEVGTIIGTVMARDPDS-ISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRE----- 450
VG I + A++PD+ + I + + R D I+ G++ T LDRE
Sbjct: 499 FGVGQEITSYTAQEPDTFMEQKITYRIWR--DTANWLEINPDTGAISTRAELDREDFEHV 556
Query: 451 LSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCE-NARPGQLIQT 509
+ + +IA + +P T + + + DVNDNAP F CE N +P Q
Sbjct: 557 KNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP-IPEPRTIFFCERNPKP----QV 611
Query: 510 ISAVDKDDPLGGQKFFFSLA-AVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVI 568
I+ +D D P F L + N+T+Q N+ I+ + E+ Y + + +
Sbjct: 612 INIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPK--MALEVGDYKINLKL 669
Query: 569 SDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIV 628
DN Q+ T+ V CD +G C +A + AGL A++ IL I+ LL+++
Sbjct: 670 MDN----QNKDQVTTLEVSVCDCEGAAGVCR-KAQPVEAGLQIPAILGILGGILALLILI 724
Query: 629 VLFAALKRQRK--KEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKL 686
+L R+R KEPL+ ++D RDN+ Y++EGGGEED Q FD+ L +
Sbjct: 725 LLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEED-QDFDLSQLHRGLDARPEVT 783
Query: 687 RRDIIPETLFIPRRTPTAPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSIAE 746
R D+ P + +PR P + ++ +FI+E LK D DPTAPPYDSL + YEG+ S A
Sbjct: 784 RNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAA 843
Query: 747 SLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGESD 785
SLSSL S ++ DQ+YDYL EWG RF KLA+MYGGGE D
Sbjct: 844 SLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD 882
>gi|4826669 cadherin 15 preproprotein [Homo sapiens]
Length = 814
Score = 362 bits (928), Expect = e-99
Identities = 258/777 (33%), Positives = 391/777 (50%), Gaps = 44/777 (5%)
Query: 31 VPQQRILSSRVPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLK 90
VP R ++ P L R +R W+ + E + Y V ++ SD+ + GS+
Sbjct: 22 VPGWRRPTTLYPWRRAPALSRVRRAWVIPPISVSENHKRLPYPLV-QIKSDKQQL-GSVI 79
Query: 91 YILSGDGAGT----LFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEF 146
Y + G G +F ID+ TG + +DRE+ + LRA A++ +E ++
Sbjct: 80 YSIQGPGVDEEPRGVFSIDKFTGKVFLNAMLDREKTDRFRLRAFALDLGG-STLEDPTDL 138
Query: 147 VIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQ 206
I + D NDN P F +E +T V E +V GT V + ATDADDP N+A + QG
Sbjct: 139 EIVVVDQNDNRPAFLQEAFTGRVLEGAVPGTYVTRAEATDADDPETDNAALRFSILQQGS 198
Query: 207 P-YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDN 265
P FS++ TG IRT ++RE Y + +Q DM G GL+ T + ITL D+NDN
Sbjct: 199 PELFSIDELTGEIRTVQVGLDREVVAVYNLTLQVADMSGD--GLTATASAIITLDDINDN 256
Query: 266 PPRFPQNTIHLRVLESSPVGTAIGSVKATDADT--GKNAEVEYRIIDGDGTDMFDIVTEK 323
P F ++ + +E+ G +G ++ D D N + I++GD F I T+
Sbjct: 257 APEFTRDEFFMEAIEAVS-GVDVGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTDP 315
Query: 324 DTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPV 383
T EG++++ K LDYES Y LKV +N + L + V++ ++D +EPPV
Sbjct: 316 KTNEGVLSIVKALDYESCEHYELKVSVQN-EAPLQAAALRAERGQAKVRVHVQDTNEPPV 374
Query: 384 FSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYT 443
F + + E GT++ T ARDPD+ R S + D + + + G + T
Sbjct: 375 FQENPLRTSLAEGAPPGTLVATFSARDPDTEQLQ-RLSYSKDYDPEDWLQVDAATGRIQT 433
Query: 444 SKPLDREL----SQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCE 499
L W+ V+A + + T + + IL+VND+AP A +C
Sbjct: 434 QHVLSPASPFLKGGWYRAIVLAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCS 493
Query: 500 NARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNP----NFTVQDNEDNTARILTRKNGFN 555
G + + A D+D P G F F L+ P N+++ + AR+ R
Sbjct: 494 EPHQGPGL-LLGATDEDLPPHGAPFHFQLSPRLPELGRNWSLSQVNVSHARLRPR----- 547
Query: 556 RHEISTYL--LPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGA 613
H++ L L +++ D+ P Q L + VC C G +A L GLS GA
Sbjct: 548 -HQVPEGLHRLSLLLRDSGQPPQQREQPLNVTVCRCGKDGVCLPGAAALLAGGTGLSLGA 606
Query: 614 LIAILLCIIILLVIVVLFAAL----KRQRKKEPLILSKEDIRDNIVSYNDEGGGEEDTQA 669
L+ +L ++LLV+V+L A K+ R K L ++D+RDN+++Y+++GGGEED A
Sbjct: 607 LVIVLASALLLLVLVLLVALRARFWKQSRGKGLLHGPQDDLRDNVLNYDEQGGGEEDQDA 666
Query: 670 FDIGTLRNPAAIE----EKKLRRDIIPETLFI--PRRTPTAPDNTDVRDFINERLKEHDL 723
+DI LR+P A+ LRRD L PR PT+P D+ DFIN+ L+ D
Sbjct: 667 YDISQLRHPTALSLPLGPPPLRRDAPQGRLHPQPPRVLPTSP--LDIADFINDGLEAADS 724
Query: 724 DPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYG 780
DP+ PPYD+ Y YEG+ S+A +LSS+ S + DQ+YDYLR+WGPRF +LA+MYG
Sbjct: 725 DPSVPPYDTALIYDYEGDGSVAGTLSSILSSQGDEDQDYDYLRDWGPRFARLADMYG 781
>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
Length = 829
Score = 350 bits (899), Expect = 2e-96
Identities = 259/780 (33%), Positives = 396/780 (50%), Gaps = 56/780 (7%)
Query: 31 VPQQRILSSRVPRS---DGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDG 87
V ++R L R P +IL R KR W+ + E G Q + +L S++D+ D
Sbjct: 81 VQERRSLKERNPLKIFPSKRILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DT 139
Query: 88 SLKYILSGDGAGT----LFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPE 143
+ Y ++G GA + +F ++++TG + + +DREE A Y L A++ +P
Sbjct: 140 KIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPM 199
Query: 144 SEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSIL 203
+ +I + D ND++P F ++ + SV E + GTSV+QVTATD DD Y + V YSI
Sbjct: 200 NISII-VTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIH 258
Query: 204 QGQP------YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNI 257
+P F++ TG I ++RE +Y + IQA DM G G + T +
Sbjct: 259 SQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVV 316
Query: 258 TLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNA--EVEYRIIDGDGTD 315
+ D NDN P F V E++ VG + + TD D + Y I+ GD D
Sbjct: 317 EILDANDNAPMFDPQKYEAHVPENA-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGD 375
Query: 316 MFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISI 375
F I T ++ +GI+T +K LD+E++ +TL VE N + F P TIV + +
Sbjct: 376 HFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTN---EAPFVLKLPTSTATIV-VHV 431
Query: 376 EDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIH 435
EDV+E PVF S + EV E I G + A DPD + I + + R D +
Sbjct: 432 EDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPDKENQKISYRILR--DPAGWLAMD 489
Query: 436 SGNGSLYTSKPLDRELSQW-----HNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFA 490
+G + LDRE Q+ + + V+A + +P T + + ++DVND+ P
Sbjct: 490 PDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPE 549
Query: 491 VFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNF-TVQDNEDNTARILT 549
T +C + + Q ++ DKD F L + + T + NE+ +L+
Sbjct: 550 PRQIT-ICNQS---PVRQVLNITDKDLSPHTSPFQAQLTDDSDIYWTAEVNEEGDTVVLS 605
Query: 550 RKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAE---ALLLP 606
K + TY + + +SD+ Q + IR CD G++++C +LP
Sbjct: 606 LKKFLKQ---DTYDVHLSLSDHGNKEQLTV----IRATVCDCHGHVETCPGPWKGGFILP 658
Query: 607 AGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEED 666
GA++A+L +++LL++V K+++ KEPL+L ++D RDN+ Y +EGGGEED
Sbjct: 659 V---LGAVLALLFLLLVLLLLV-----RKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEED 710
Query: 667 TQAFDIGTL-RNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNTDVRDFINERLKEHDLDP 725
Q +DI L R A E LR D+ P + P P + ++ +FI E LK + DP
Sbjct: 711 -QDYDITQLHRGLEARPEVVLRNDVAPTIIPTPMYRPRPANPDEIGNFIIENLKAANTDP 769
Query: 726 TAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGESD 785
TAPPYD+L + YEG+ S A SLSSL S ++ DQ+YDYL EWG RF KLA+MYGGGE D
Sbjct: 770 TAPPYDTLLVFDYEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD 829
>gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens]
Length = 840
Score = 252 bits (643), Expect = 1e-66
Identities = 212/659 (32%), Positives = 322/659 (48%), Gaps = 45/659 (6%)
Query: 36 ILSSRVPRSDGK------ILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSL 89
+LS+R +S K L R KR W L+E G Q+V ++ SD + + ++
Sbjct: 110 VLSARENKSPKKRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ-NYTI 168
Query: 90 KYILSGDGAG----TLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESE 145
Y +SG G LF I++ TGDI TR IDRE+ + L A P P
Sbjct: 169 FYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYP-LP 227
Query: 146 FVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQG 205
+IKI D NDN P F + +VPE GTSV +VTATD D+P ++ R+ Y ILQ
Sbjct: 228 LIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQ 286
Query: 206 QP----YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTD 261
P +FS+ P+TG+I T P ++RE + YQ++++ +DMGGQ GL T T+ I+L D
Sbjct: 287 IPDHPKHFSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLED 346
Query: 262 VNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDAD--TGKNAEVEYRIIDGDGTDMFDI 319
NDNPP F + T ++ +E + + I +K D D +++ Y+I+ G+ F I
Sbjct: 347 ENDNPPSFTE-TSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFII 405
Query: 320 VTEKDTQEGIITVKKPLDYESRRLYTLKVEAEN-THVDPRFYYLGPFKDTTIVKISIEDV 378
T+ +T EG++ V KPL+YE R L+V N P TT V + I D
Sbjct: 406 STDPNTNEGVLCVVKPLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDS 465
Query: 379 DEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGN 438
DE P + + + G + A DP+ ISS + D D F I+
Sbjct: 466 DEGPECHPPVKVIQSQDGFPAGQELLGYKALDPE-ISSGEGLRYQKLGDEDNWFEINQHT 524
Query: 439 GSLYTSKPLDRE----LSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYD 494
G L T K LDRE + +N++V+A + T + V + D ND+APQ + +
Sbjct: 525 GDLRTLKVLDRESKFVKNNQYNISVVAVDAVGRSCTG--TLVVHLDDYNDHAPQ--IDKE 580
Query: 495 TFVCENARPGQLIQTISAVDKDDPLGGQKF-FFSLAAVNPNFTVQDNEDNTARILTRKNG 553
+C+N + + VD D P G F FF + + N+ +++ + TA + R+N
Sbjct: 581 VTICQN---NEDFAVLKPVDPDGPENGPPFQFFLDNSASKNWNIEEKDGKTAILRQRQN- 636
Query: 554 FNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACD--SQGNMQSCSAEALLLPAGLST 611
+ + Y +P+ I D + +T LT+RVC C S+ M+ S + L
Sbjct: 637 ---LDYNYYSVPIQIKDRHGLV--ATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGR 691
Query: 612 GALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDI-RDNIVSYNDEGGGEEDTQA 669
A++A++L ++LL I LF K+ EDI + N++ N EG GEE T+A
Sbjct: 692 WAILAMVLGSVLLLCI--LFTCFCVTAKRTVKKCFPEDIAQQNLIVSNTEGPGEEVTEA 748
>gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
Length = 894
Score = 252 bits (643), Expect = 1e-66
Identities = 212/659 (32%), Positives = 322/659 (48%), Gaps = 45/659 (6%)
Query: 36 ILSSRVPRSDGK------ILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSL 89
+LS+R +S K L R KR W L+E G Q+V ++ SD + + ++
Sbjct: 110 VLSARENKSPKKRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ-NYTI 168
Query: 90 KYILSGDGAG----TLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESE 145
Y +SG G LF I++ TGDI TR IDRE+ + L A P P
Sbjct: 169 FYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYP-LP 227
Query: 146 FVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQG 205
+IKI D NDN P F + +VPE GTSV +VTATD D+P ++ R+ Y ILQ
Sbjct: 228 LIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQ 286
Query: 206 QP----YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTD 261
P +FS+ P+TG+I T P ++RE + YQ++++ +DMGGQ GL T T+ I+L D
Sbjct: 287 IPDHPKHFSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLED 346
Query: 262 VNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDAD--TGKNAEVEYRIIDGDGTDMFDI 319
NDNPP F + T ++ +E + + I +K D D +++ Y+I+ G+ F I
Sbjct: 347 ENDNPPSFTE-TSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFII 405
Query: 320 VTEKDTQEGIITVKKPLDYESRRLYTLKVEAEN-THVDPRFYYLGPFKDTTIVKISIEDV 378
T+ +T EG++ V KPL+YE R L+V N P TT V + I D
Sbjct: 406 STDPNTNEGVLCVVKPLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDS 465
Query: 379 DEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGN 438
DE P + + + G + A DP+ ISS + D D F I+
Sbjct: 466 DEGPECHPPVKVIQSQDGFPAGQELLGYKALDPE-ISSGEGLRYQKLGDEDNWFEINQHT 524
Query: 439 GSLYTSKPLDRE----LSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYD 494
G L T K LDRE + +N++V+A + T + V + D ND+APQ + +
Sbjct: 525 GDLRTLKVLDRESKFVKNNQYNISVVAVDAVGRSCTG--TLVVHLDDYNDHAPQ--IDKE 580
Query: 495 TFVCENARPGQLIQTISAVDKDDPLGGQKF-FFSLAAVNPNFTVQDNEDNTARILTRKNG 553
+C+N + + VD D P G F FF + + N+ +++ + TA + R+N
Sbjct: 581 VTICQN---NEDFAVLKPVDPDGPENGPPFQFFLDNSASKNWNIEEKDGKTAILRQRQN- 636
Query: 554 FNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACD--SQGNMQSCSAEALLLPAGLST 611
+ + Y +P+ I D + +T LT+RVC C S+ M+ S + L
Sbjct: 637 ---LDYNYYSVPIQIKDRHGLV--ATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGR 691
Query: 612 GALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDI-RDNIVSYNDEGGGEEDTQA 669
A++A++L ++LL I LF K+ EDI + N++ N EG GEE T+A
Sbjct: 692 WAILAMVLGSVLLLCI--LFTCFCVTAKRTVKKCFPEDIAQQNLIVSNTEGPGEEVTEA 748
>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
sapiens]
Length = 896
Score = 247 bits (630), Expect = 3e-65
Identities = 238/808 (29%), Positives = 367/808 (45%), Gaps = 95/808 (11%)
Query: 33 QQRILSSRVPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYI 92
Q+++ +R R +L R KR W + E G ++ ++ SD + + ++ Y
Sbjct: 116 QKKVSKTRHTRET--VLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQ-NYTVFYS 172
Query: 93 LSGDGAG----TLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVI 148
+SG G LF I+ TG++ TR +DREE + L A A P I
Sbjct: 173 ISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLP-LPLPI 231
Query: 149 KIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP- 207
++ D NDN P F E IY V E S GT+V V ATD D+P ++ R+ YSILQ P
Sbjct: 232 RVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPR 290
Query: 208 ---YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVND 264
FSV P TG+I T ++RE ++Y ++++ +DM GQ GL GT+T IT+TD ND
Sbjct: 291 SPGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSND 350
Query: 265 NPPRFPQNTIHLRVLESSPVGTAIGSVKATDAD--TGKNAEVEYRIIDGDGTDMFDIVTE 322
N P F QN V E + I + D D N V + I+ G+ F I T+
Sbjct: 351 NAPTFRQNAYEAFV-EENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTD 409
Query: 323 KDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPP 382
K+T EG+++V KPL+YE R L++ N R + +V + + D+DE P
Sbjct: 410 KETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGP 469
Query: 383 VFSRSSYLFEVHEDIEVGTIIGTVMARDPDSIS-SPIRFSLDRHTDLDRIFNIHSGNGSL 441
+ ++ + E++ VG+ I A DP++ + + +R+ + D I +GS+
Sbjct: 470 ECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYK--KLHDPKGWITIDEISGSI 527
Query: 442 YTSKPLDREL----SQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFV 497
TSK LDRE+ ++ +N+TV+A + ++ T +A V I DVNDN P+ Y +
Sbjct: 528 ITSKILDREVETPKNELYNITVLAIDKDDRSCTGTLA--VNIEDVNDNPPEILQEY-VVI 584
Query: 498 CENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPN----FTVQDNEDNTARILTRKN- 552
C +P I AVD D+P+ G F+FSL +P +++ D AR+ +KN
Sbjct: 585 C---KPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNA 641
Query: 553 GFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTG 612
GF Y +P+ + D Q++T L + +C C + C A + L
Sbjct: 642 GFQE-----YTIPITVKDR--AGQAATKLLRVNLCECT---HPTQCRATSRSTGVILGKW 691
Query: 613 ALIAILLCI-----IILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEE-- 665
A++AILL I ++L ++ +F A K +R E L + N++ N E G++
Sbjct: 692 AILAILLGIALLFSVLLTLVCGVFGATKGKRFPEDL------AQQNLIISNTEAPGDDRV 745
Query: 666 -DTQAFDIGTLRNPA-----------------AIEEKKLRRDIIP--------ETLFIPR 699
F T N + IE K + TL R
Sbjct: 746 CSANGFMTQTTNNSSQGFCGTMGSGMKNGGQETIEMMKGGNQTLESCRGAGHHHTLDSCR 805
Query: 700 RTPTAPDN-----TDVRDFINERLKE-----HDLDPTAPPYDSLATYAYEGNDSIAESLS 749
T DN ++ F RL E + + P D + TY YEG S A S+
Sbjct: 806 GGHTEVDNCRYTYSEWHSFTQPRLGEKLHRCNQNEDRMPSQDYVLTYNYEGRGSPAGSVG 865
Query: 750 SLESGTTEGDQNYDYLREWGPRFNKLAE 777
+ + D+L P+F LAE
Sbjct: 866 CCSE--KQEEDGLDFLNNLEPKFITLAE 891
>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
Length = 839
Score = 243 bits (619), Expect = 7e-64
Identities = 205/658 (31%), Positives = 322/658 (48%), Gaps = 55/658 (8%)
Query: 33 QQRILSSRVPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYI 92
Q+++ +R R +L R KR W + E G ++ ++ SD + + ++ Y
Sbjct: 116 QKKVSKTRHTRET--VLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQ-NYTVFYS 172
Query: 93 LSGDGAG----TLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVI 148
+SG G LF I+ TG++ TR +DREE + L A A P I
Sbjct: 173 ISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLP-LPLPI 231
Query: 149 KIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP- 207
++ D NDN P F E IY V E S GT+V V ATD D+P ++ R+ YSILQ P
Sbjct: 232 RVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPR 290
Query: 208 ---YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVND 264
FSV P TG+I T ++RE ++Y ++++ +DM GQ GL GT+T IT+TD ND
Sbjct: 291 SPGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSND 350
Query: 265 NPPRFPQNTIHLRVLESSPVGTAIGSVKATDAD--TGKNAEVEYRIIDGDGTDMFDIVTE 322
N P F QN V E + I + D D N V + I+ G+ F I T+
Sbjct: 351 NAPTFRQNAYEAFV-EENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTD 409
Query: 323 KDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPP 382
K+T EG+++V KPL+YE R L++ N R + +V + + D+DE P
Sbjct: 410 KETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGP 469
Query: 383 VFSRSSYLFEVHEDIEVGTIIGTVMARDPDSIS-SPIRFSLDRHTDLDRIFNIHSGNGSL 441
+ ++ + E++ VG+ I A DP++ + + +R+ + D I +GS+
Sbjct: 470 ECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYK--KLHDPKGWITIDEISGSI 527
Query: 442 YTSKPLDREL----SQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFV 497
TSK LDRE+ ++ +N+TV+A + ++ T +A V I DVNDN P+ Y +
Sbjct: 528 ITSKILDREVETPKNELYNITVLAIDKDDRSCTGTLA--VNIEDVNDNPPEILQEY-VVI 584
Query: 498 CENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPN----FTVQDNEDNTARILTRKN- 552
C +P I AVD D+P+ G F+FSL +P +++ D AR+ +KN
Sbjct: 585 C---KPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNA 641
Query: 553 GFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTG 612
GF Y +P+ + D Q++T L + +C C + C A + L
Sbjct: 642 GFQE-----YTIPITVKDR--AGQAATKLLRVNLCECT---HPTQCRATSRSTGVILGKW 691
Query: 613 ALIAILLCI-----IILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEE 665
A++AILL I ++L ++ +F A K +R E L + N++ N E G++
Sbjct: 692 AILAILLGIALLFSVLLTLVCGVFGATKGKRFPEDL------AQQNLIISNTEAPGDD 743
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 233 bits (593), Expect = 7e-61
Identities = 197/654 (30%), Positives = 316/654 (48%), Gaps = 42/654 (6%)
Query: 33 QQRILSSRVPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYI 92
Q ++L R + K+L R KR W +LE G ++ ++ SD + + ++ Y
Sbjct: 116 QTKVLKKRHTKE--KVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQ-NYTIYYS 172
Query: 93 LSGDGAG----TLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVI 148
+ G G LF ++ TG+++ TR +DRE+ + + A A P P +I
Sbjct: 173 IRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELP-LPLII 231
Query: 149 KIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP- 207
KI D NDN P F EE YT ++ E VGT+V QV ATD D+P ++ R+ YSI+ P
Sbjct: 232 KIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPP 290
Query: 208 ---YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVND 264
FS+ P TG+I T ++RE ++YQ+ I+ +DM GQ GL T+T I + DVND
Sbjct: 291 SPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVND 350
Query: 265 NPPRFPQNTIHLRVLESSPVGTAIGSVKATDAD--TGKNAEVEYRIIDGDGTDMFDIVTE 322
+ P F + T ++ +E + V I V D D N Y I+ G+ F IVT+
Sbjct: 351 HLPTFTR-TSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTD 409
Query: 323 KDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPP 382
T EG++ V KPL+YE ++ L++ N R T V +++ED DE P
Sbjct: 410 AKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGP 469
Query: 383 VFSRSSYLFEVHEDIEVGTIIGTVMARDPDS-ISSPIRFSLDRHTDLDRIFNIHSGNGSL 441
+ + E+ EVGT A DP++ SS IR+ + TD I GS+
Sbjct: 470 ECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYK--KLTDPTGWVTIDENTGSI 527
Query: 442 YTSKPLDREL----SQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFV 497
+ LDRE + +N+TV+A++ T + + ++ DVNDN+P F +
Sbjct: 528 KVFRSLDREAETIKNGIYNITVLASDQGGRTCTGTLGIILQ--DVNDNSP-FIPKKTVII 584
Query: 498 CENARPGQLIQTISAVDKDDPLGGQKFFFSL----AAVNPNFTVQDNEDNTARILTRKNG 553
C +P I AVD D+P+ G F FSL + V + ++ D AR+ +
Sbjct: 585 C---KPTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQ--- 638
Query: 554 FNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTG- 612
N +Y++P+ + D SS +L + +C C ++ N + + + G+ G
Sbjct: 639 -NDPPFGSYVVPITVRDR--LGMSSVTSLDVTLCDCITE-NDCTHRVDPRIGGGGVQLGK 694
Query: 613 -ALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEE 665
A++AILL I +L I+ K+P ++ + + N++ N E G++
Sbjct: 695 WAILAILLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 233 bits (593), Expect = 7e-61
Identities = 197/654 (30%), Positives = 316/654 (48%), Gaps = 42/654 (6%)
Query: 33 QQRILSSRVPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYI 92
Q ++L R + K+L R KR W +LE G ++ ++ SD + + ++ Y
Sbjct: 116 QTKVLKKRHTKE--KVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQ-NYTIYYS 172
Query: 93 LSGDGAG----TLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVI 148
+ G G LF ++ TG+++ TR +DRE+ + + A A P P +I
Sbjct: 173 IRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELP-LPLII 231
Query: 149 KIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP- 207
KI D NDN P F EE YT ++ E VGT+V QV ATD D+P ++ R+ YSI+ P
Sbjct: 232 KIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPP 290
Query: 208 ---YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVND 264
FS+ P TG+I T ++RE ++YQ+ I+ +DM GQ GL T+T I + DVND
Sbjct: 291 SPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVND 350
Query: 265 NPPRFPQNTIHLRVLESSPVGTAIGSVKATDAD--TGKNAEVEYRIIDGDGTDMFDIVTE 322
+ P F + T ++ +E + V I V D D N Y I+ G+ F IVT+
Sbjct: 351 HLPTFTR-TSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTD 409
Query: 323 KDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPP 382
T EG++ V KPL+YE ++ L++ N R T V +++ED DE P
Sbjct: 410 AKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGP 469
Query: 383 VFSRSSYLFEVHEDIEVGTIIGTVMARDPDS-ISSPIRFSLDRHTDLDRIFNIHSGNGSL 441
+ + E+ EVGT A DP++ SS IR+ + TD I GS+
Sbjct: 470 ECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYK--KLTDPTGWVTIDENTGSI 527
Query: 442 YTSKPLDREL----SQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFV 497
+ LDRE + +N+TV+A++ T + + ++ DVNDN+P F +
Sbjct: 528 KVFRSLDREAETIKNGIYNITVLASDQGGRTCTGTLGIILQ--DVNDNSP-FIPKKTVII 584
Query: 498 CENARPGQLIQTISAVDKDDPLGGQKFFFSL----AAVNPNFTVQDNEDNTARILTRKNG 553
C +P I AVD D+P+ G F FSL + V + ++ D AR+ +
Sbjct: 585 C---KPTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQ--- 638
Query: 554 FNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTG- 612
N +Y++P+ + D SS +L + +C C ++ N + + + G+ G
Sbjct: 639 -NDPPFGSYVVPITVRDR--LGMSSVTSLDVTLCDCITE-NDCTHRVDPRIGGGGVQLGK 694
Query: 613 -ALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEE 665
A++AILL I +L I+ K+P ++ + + N++ N E G++
Sbjct: 695 WAILAILLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 225 bits (573), Expect = 1e-58
Identities = 193/589 (32%), Positives = 294/589 (49%), Gaps = 50/589 (8%)
Query: 51 RQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGT----LFIIDE 106
RQKR + + + E + VGK+ D D+ + S K+ L+G G +F I+E
Sbjct: 135 RQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPERS-KFRLTGKGVDQEPKGIFRINE 192
Query: 107 KTGDIHATRRIDREEKAFYTLRAQA--INRRTLRPVEPESEFVIKIHDINDNEPTFPEEI 164
TG + TR +DRE A Y L + +N +TL P VI D NDN P F E
Sbjct: 193 NTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVI---DQNDNRPIFREGP 249
Query: 165 YTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP------YFSVEPETGII 218
Y V E S GT+V+++TA DADDP+ N A + Y+I Q P F ++PE G I
Sbjct: 250 YIGHVMEGSPTGTTVMRMTAFDADDPATDN-ALLRYNIRQQTPDKPSPNMFYIDPEKGDI 308
Query: 219 RTALPN--MNRENRE--QYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTI 274
T + ++RE E +Y+++I+A+DM G GL+GT T I + D ND+ P+F +
Sbjct: 309 VTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEF 368
Query: 275 HLRVLESSPVGTAIG-SVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVK 333
V E VG + +V+ D T Y II+G+ F+I T T EG+++V
Sbjct: 369 QATV-EEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVV 427
Query: 334 KPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEV 393
KPLDYE +TL ++ EN GP T V I++ DV+E PVF +
Sbjct: 428 KPLDYEISAFHTLLIKVENEDPLVPDVSYGP-SSTATVHITVLDVNEGPVFYPDPMMVTR 486
Query: 394 HEDIEVGTIIGTVMARDPDSIS-SPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDREL- 451
ED+ VG+++ TV A DPDS+ IR+S+ + D NI+ NG++ T+ LDRE
Sbjct: 487 QEDLSVGSVLLTVNATDPDSLQHQTIRYSV--YKDPAGWLNINPINGTVDTTAVLDRESP 544
Query: 452 ---SQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTF--VCENARPGQL 506
+ + +A + NP T + + + DVNDNAP Y T VC++A+ +
Sbjct: 545 FVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAP---FIYPTVAEVCDDAKNLSV 601
Query: 507 IQTISAVDKD-----DPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEIST 561
+ + A DKD DP KF AV +NT +++ N+ +
Sbjct: 602 V-ILGASDKDLHPNTDPF---KFEIHKQAVPDKVWKISKINNTHALVSLLQNLNK---AN 654
Query: 562 YLLPVVISDNDYPIQSSTGTLTIRVCAC-DSQGNMQSCSAEALLLPAGL 609
Y LP++++D+ P ++ L ++VC+C +S+ + + A LP+ L
Sbjct: 655 YNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALRFSLPSVL 703
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 209 bits (533), Expect = 6e-54
Identities = 156/516 (30%), Positives = 254/516 (49%), Gaps = 31/516 (6%)
Query: 80 SDQDKG-DGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLR 138
+D D G +G L Y +SG + F+ID +TG + +DRE YTL + +
Sbjct: 742 TDLDTGFNGKLVYAVSGGNEDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIPQ 801
Query: 139 PVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARV 198
V+ + D NDN P F +E Y V E V + ++QV ATD D G + V
Sbjct: 802 KAAWRLLHVVVV-DANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKD---LGPNGHV 857
Query: 199 IYSILQGQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNIT 258
YSI+ FS++ TG++ A P ++RE + ++ + I+A+D + L T V ++
Sbjct: 858 TYSIVTDTDTFSIDSVTGVVNIARP-LDRELQHEHSLKIEARDQAREEPQLFSTVVVKVS 916
Query: 259 LTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFD 318
L DVNDNPP F ++V E P GT I ++A D D G++ +V Y ++D G FD
Sbjct: 917 LEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLD-HGEGNFD 975
Query: 319 IVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDV 378
+ D G + + + LD+E +++Y L V A++ T V++ + DV
Sbjct: 976 V----DKLSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPV------SLSSTCYVEVEVVDV 1025
Query: 379 DE---PPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDS-ISSPIRFSLDRHTDLDRIFNI 434
+E PPVFS V ED VG+++ TV A D D+ IR+S+ + + +F I
Sbjct: 1026 NENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSGVG-VFKI 1084
Query: 435 HSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFA--VF 492
G + TS LDRE + + LTV A + ++ + +++ + DVNDNAPQ + V+
Sbjct: 1085 GEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVY 1144
Query: 493 YDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPN--FTVQDNEDNTARILTR 550
Y + EN+ + I A D D K + + + NP F++ T I T
Sbjct: 1145 YPE-IMENSPKDVSVVQIEAFDPDSS-SNDKLMYKITSGNPQGFFSI---HPKTGLITTT 1199
Query: 551 KNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRV 586
+R + ++L V ++DN P +S+ + +++
Sbjct: 1200 SRKLDREQQDEHILEVTVTDNGSPPKSTIARVIVKI 1235
Score = 202 bits (513), Expect = 1e-51
Identities = 159/507 (31%), Positives = 242/507 (47%), Gaps = 28/507 (5%)
Query: 84 KGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPE 143
+ + + Y L G GA F ++ TG++ + +DREE+A Y L +A + +
Sbjct: 3053 RSNAEITYTLLGSGAEK-FKLNPDTGELKTSTPLDREEQAVYHLLVRATDGGGRFC---Q 3108
Query: 144 SEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSIL 203
+ V+ + D+NDN P F + Y +V E + GT + +V ATDAD G + +++YS++
Sbjct: 3109 ASIVLTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADA---GLNRKILYSLI 3165
Query: 204 QGQP-YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDV 262
FS+ +GII+ P ++RE + Y + ++A D G L+ T TV +++ D+
Sbjct: 3166 DSADGQFSINELSGIIQLEKP-LDRELQAVYTLSLKAVDQGLPRR-LTATGTVIVSVLDI 3223
Query: 263 NDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTE 322
NDNPP F V E VGT + V A D NAE+ Y II G+ F I
Sbjct: 3224 NDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGKFSI--- 3280
Query: 323 KDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDV-DEP 381
D++ G + + + LDYES Y L VEA + D V +++ D+ D
Sbjct: 3281 -DSKTGAVFIIENLDYESSHEYYLTVEATDGGTPS-------LSDVATVNVNVTDINDNT 3332
Query: 382 PVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSIS-SPIRFSLDRHTDLDRIFNIHSGNGS 440
PVFS+ +Y + ED + + TVMA D D S S I +S+ F I G
Sbjct: 3333 PVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSHIHYSIIDGNQ-GSSFTIDPVRGE 3391
Query: 441 LYTSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVF-YDTFVCE 499
+ +K LDRE + LTV A++ +P V + + DVNDNAP F+ Y + E
Sbjct: 3392 VKVTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFSRGNYSVIIQE 3451
Query: 500 NARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEI 559
N G + + D+D G FFF++ N + N +L + R E
Sbjct: 3452 NKPVGFSVLQLVVTDEDSSHNGPPFFFTIVTGNDEKAFEVNPQG---VLLTSSAIKRKEK 3508
Query: 560 STYLLPVVISDNDYPIQSSTGTLTIRV 586
YLL V ++DN P SS + IRV
Sbjct: 3509 DHYLLQVKVADNGKPQLSSLTYIDIRV 3535
Score = 194 bits (494), Expect = 2e-49
Identities = 158/517 (30%), Positives = 261/517 (50%), Gaps = 41/517 (7%)
Query: 80 SDQDKGDGSLKYILSGDGAGTLFIID--EKTGDIHATRRIDREEKAFYTLRAQAINRRTL 137
+D ++ + + Y ++G F ++ + ++ + +DRE++ Y L A T
Sbjct: 2945 ADSEEINRQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITA----TD 3000
Query: 138 RPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSAR 197
++ +K+ D NDN P + +Y+ ++PE + G ++Q++ATDAD S +A
Sbjct: 3001 GTFSSKAIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRS---NAE 3057
Query: 198 VIYSIL-QGQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVN 256
+ Y++L G F + P+TG ++T+ P ++RE + Y ++++A D GG+ S +
Sbjct: 3058 ITYTLLGSGAEKFKLNPDTGELKTSTP-LDREEQAVYHLLVRATDGGGRFCQAS----IV 3112
Query: 257 ITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIID-GDGTD 315
+TL DVNDN P F + + V E++ GT + V+ATDAD G N ++ Y +ID DG
Sbjct: 3113 LTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLIDSADG-- 3170
Query: 316 MFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISI 375
F I + GII ++KPLD E + +YTL ++A + + R G T++ +
Sbjct: 3171 QFSI----NELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATG-----TVIVSVL 3221
Query: 376 EDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPD-SISSPIRFSLDRHTDLDRIFNI 434
+ D PPVF Y V EDI VGT + V A D ++ I +S+ + + F+I
Sbjct: 3222 DINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGK-FSI 3280
Query: 435 HSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAV-FY 493
S G+++ + LD E S + LTV A + P + V V + D+NDN P F+ Y
Sbjct: 3281 DSKTGAVFIIENLDYESSHEYYLTVEATDGGTPSLSDVATVNVNVTDINDNTPVFSQDTY 3340
Query: 494 DTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVN--PNFTVQD--NEDNTARILT 549
T + E+A Q + T+ A D D P +S+ N +FT+ E ++L
Sbjct: 3341 TTVISEDAVLEQSVITVMADDADGP-SNSHIHYSIIDGNQGSSFTIDPVRGEVKVTKLL- 3398
Query: 550 RKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRV 586
+R IS Y L V SDN P + +T T+ I V
Sbjct: 3399 -----DRETISGYTLTVQASDNGSPPRVNTTTVNIDV 3430
Score = 191 bits (486), Expect = 2e-48
Identities = 149/494 (30%), Positives = 236/494 (47%), Gaps = 33/494 (6%)
Query: 102 FIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFP 161
F+ID ++G + + +D E +Y A + + + I++ D NDN P F
Sbjct: 2751 FVIDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFE 2810
Query: 162 EEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPY-----FSVEPETG 216
Y A + E G+ V+Q+ A+DAD G + +V+YS+ Q Q F++ ETG
Sbjct: 2811 SSPYEAFIVENLPGGSRVIQIRASDADS---GTNGQVMYSLDQSQSVEVIESFAINMETG 2867
Query: 217 IIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHL 276
I T L ++ E R+ YQ+ + A D G ++ LS T V++T+TDVND+PPRF
Sbjct: 2868 WI-TTLKELDHEKRDNYQIKVVASDHGEKIQ-LSSTAIVDVTVTDVNDSPPRFTAEIYKG 2925
Query: 277 RVLESSPVGTAIGSVKATDADTGK-NAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKP 335
V E P G I + TDAD+ + N +V Y I GD F + T ++ E + VKKP
Sbjct: 2926 TVSEDDPQGGVIAILSTTDADSEEINRQVTYFITGGDPLGQFAVETIQN--EWKVYVKKP 2983
Query: 336 LDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDV-DEPPVFSRSSYLFEVH 394
LD E R Y L + A + G F IV++ + D D PV ++ Y +
Sbjct: 2984 LDREKRDNYLLTITATD----------GTFSSKAIVEVKVLDANDNSPVCEKTLYSDTIP 3033
Query: 395 EDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQW 454
ED+ G +I + A D D I S + F ++ G L TS PLDRE
Sbjct: 3034 EDVLPGKLIMQISATDAD-IRSNAEITYTLLGSGAEKFKLNPDTGELKTSTPLDREEQAV 3092
Query: 455 HNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVF-YDTFVCENARPGQLIQTISAV 513
++L V A + + ++ + + DVNDNAP+F+ Y V EN PG L+ + A
Sbjct: 3093 YHLLVRATD--GGGRFCQASIVLTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQAT 3150
Query: 514 DKDDPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDY 573
D D L + + + + + F++ + + I+ + +R + Y L + D
Sbjct: 3151 DADAGLNRKILYSLIDSADGQFSINE----LSGIIQLEKPLDRELQAVYTLSLKAVDQGL 3206
Query: 574 PIQ-SSTGTLTIRV 586
P + ++TGT+ + V
Sbjct: 3207 PRRLTATGTVIVSV 3220
Score = 179 bits (453), Expect = 1e-44
Identities = 146/527 (27%), Positives = 249/527 (47%), Gaps = 52/527 (9%)
Query: 79 HSDQDKGDGSLKY-ILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTL 137
H + + DG ++Y I G G G +F I E+TG I + R+DRE + Y L A ++ +
Sbjct: 1059 HDEDARRDGEIRYSIRDGSGVG-VFKIGEETGVIETSDRLDRESTSHYWLTVFATDQGVV 1117
Query: 138 RPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSAR 197
P+ E I++ D+NDN P E +Y + E S SVVQ+ +A DP ++ +
Sbjct: 1118 -PLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQI---EAFDPDSSSNDK 1173
Query: 198 VIYSILQGQP--YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTV 255
++Y I G P +FS+ P+TG+I T ++RE ++++ + + D G S V
Sbjct: 1174 LMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSP--PKSTIARV 1231
Query: 256 NITLTDVNDNPPRFPQNTIHLRV-------LESSPVGTAIGSVKATDADTGKNAEVEYRI 308
+ + D NDN P+F Q +R+ E + + V ATD D G NAE+ Y I
Sbjct: 1232 IVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDEGPNAEISYSI 1291
Query: 309 IDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLY-TLKVEAENTHVDPRFYYLGPFKD 367
DG+ F I + + G+++ K+ + + Y L ++A + G +
Sbjct: 1292 EDGNEHGKFFI----EPKTGVVSSKR---FSAAGEYDILSIKAVDN---------GRPQK 1335
Query: 368 TTIVKISIEDVD------EPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFS 421
++ ++ IE + EP F S + F V E V +IG + P P+ F
Sbjct: 1336 SSTTRLHIEWISKPKPSLEPISFEESFFTFTVMESDPVAHMIGVISVEPP---GIPLWFD 1392
Query: 422 LDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRILD 481
+ + D F++ G G++ +KPLD E +NLTV E + T VF++++D
Sbjct: 1393 I-TGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTV---EATDGTTTILTQVFIKVID 1448
Query: 482 VNDNAPQFAVF-YDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSL-AAVNPNFTVQD 539
ND+ PQF+ Y+ + E+ P I ISAVD+D+ K ++L ++ +P +
Sbjct: 1449 TNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEK---NKLIYTLQSSRDPLSLKKF 1505
Query: 540 NEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRV 586
D L + + + L V++ D D P++ + + + V
Sbjct: 1506 RLDPATGSLYTSEKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNV 1552
Score = 177 bits (448), Expect = 4e-44
Identities = 133/428 (31%), Positives = 216/428 (50%), Gaps = 27/428 (6%)
Query: 96 DGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDIND 155
D A F I+E +G I + +DRE +A YTL +A+++ R + ++ + DIND
Sbjct: 3166 DSADGQFSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDIND 3225
Query: 156 NEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPY--FSVEP 213
N P F Y A+V E +VGT V+QV A D + +A + YSI+ G + FS++
Sbjct: 3226 NPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEA---NAEITYSIISGNEHGKFSIDS 3282
Query: 214 ETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNT 273
+TG + + N++ E+ +Y + ++A D G LS TVN+ +TD+NDN P F Q+T
Sbjct: 3283 KTGAV-FIIENLDYESSHEYYLTVEATD--GGTPSLSDVATVNVNVTDINDNTPVFSQDT 3339
Query: 274 IHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVK 333
+ E + + ++ +V A DAD N+ + Y IIDG+ F I D G + V
Sbjct: 3340 YTTVISEDAVLEQSVITVMADDADGPSNSHIHYSIIDGNQGSSFTI----DPVRGEVKVT 3395
Query: 334 KPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDV-DEPPVFSRSSYLFE 392
K LD E+ YTL V+A + PR +TT V I + DV D PVFSR +Y
Sbjct: 3396 KLLDRETISGYTLTVQASDNGSPPRV-------NTTTVNIDVSDVNDNAPVFSRGNYSVI 3448
Query: 393 VHEDIEVGTIIGTVMARDPDSISS--PIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRE 450
+ E+ VG + ++ D DS + P F++ D ++ F ++ G L TS + R+
Sbjct: 3449 IQENKPVGFSVLQLVVTDEDSSHNGPPFFFTIVTGND-EKAFEVNP-QGVLLTSSAIKRK 3506
Query: 451 LSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENAR--PGQLIQ 508
+ L V A+ P+ ++ + +R+++ + P + F+ + G +I
Sbjct: 3507 EKDHYLLQVKVADNGKPQLSSLTYIDIRVIEESIYPPAILPL-EIFITSSGEEYSGGVIG 3565
Query: 509 TISAVDKD 516
I A D+D
Sbjct: 3566 KIHATDQD 3573
Score = 168 bits (426), Expect = 2e-41
Identities = 156/526 (29%), Positives = 245/526 (46%), Gaps = 50/526 (9%)
Query: 80 SDQDKG-DGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLR 138
+D+D G +G + Y + D F ID TG ++ R +DRE + ++L+ +A ++
Sbjct: 847 TDKDLGPNGHVTYSIVTDT--DTFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQAREE 904
Query: 139 PVEPESEFVIKI--HDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSA 196
P + S V+K+ D+NDN PTF Y V E GT ++ + +A DP G S
Sbjct: 905 P-QLFSTVVVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWL---EAHDPDLGQSG 960
Query: 197 RVIYSILQ-GQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTV 255
+V YS+L G+ F V+ +G +R + ++ E ++ Y + ++AKD G + LS T V
Sbjct: 961 QVRYSLLDHGEGNFDVDKLSGAVRI-VQQLDFEKKQVYNLTVRAKDKGKPVS-LSSTCYV 1018
Query: 256 NITLTDVNDN--PPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDG 313
+ + DVN+N PP F V E +PVG+ + +V A D D ++ E+ Y I DG G
Sbjct: 1019 EVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSG 1078
Query: 314 TDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKI 373
+F I E G+I LD ES Y L V A + V P ++ + I
Sbjct: 1079 VGVFKIGEET----GVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIE-------IYI 1127
Query: 374 SIEDV-DEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIF 432
+EDV D P S Y E+ E+ + + A DPDS S+ + F
Sbjct: 1128 EVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLMYKITSGNPQGFF 1187
Query: 433 NIHSGNGSLYT-SKPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQF-A 490
+IH G + T S+ LDRE H L V + +P ++T V V+ILD NDN PQF
Sbjct: 1188 SIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIARVIVKILDENDNKPQFLQ 1247
Query: 491 VFYDTFVCENARPG-------QLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDNEDN 543
FY + E +P + + + A DKD+ + +++++D ++
Sbjct: 1248 KFYKIRLPEREKPDRERNARREPLYHVIATDKDEGPNAE----------ISYSIEDGNEH 1297
Query: 544 TARILTRKNGFNRHEISTY-----LLPVVISDNDYPIQSSTGTLTI 584
+ K G + + +L + DN P +SST L I
Sbjct: 1298 GKFFIEPKTGVVSSKRFSAAGEYDILSIKAVDNGRPQKSSTTRLHI 1343
Score = 167 bits (424), Expect = 3e-41
Identities = 124/382 (32%), Positives = 203/382 (53%), Gaps = 30/382 (7%)
Query: 151 HDINDNEPTFPEEIYTA-SVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQG--QP 207
H +N + P F + T V E VG+SV+ + +TD D G + +++Y++ G
Sbjct: 707 HSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDT---GFNGKLVYAVSGGNEDS 763
Query: 208 YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPP 267
F ++ ETG+++ P ++RE ++Y + I D+G + + +++ + D NDNPP
Sbjct: 764 CFMIDMETGMLKILSP-LDRETTDKYTLNITVYDLG--IPQKAAWRLLHVVVVDANDNPP 820
Query: 268 RFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQE 327
F Q + + V E V + I V+ATD D G N V Y I+ TD F I D+
Sbjct: 821 EFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSIV--TDTDTFSI----DSVT 874
Query: 328 GIITVKKPLDYESRRLYTLKVEA-ENTHVDPRFYYLGPFKDTTIVKISIEDV-DEPPVFS 385
G++ + +PLD E + ++LK+EA + +P+ + T +VK+S+EDV D PP F
Sbjct: 875 GVVNIARPLDRELQHEHSLKIEARDQAREEPQLF------STVVVKVSLEDVNDNPPTFI 928
Query: 386 RSSYLFEVHEDIEVGTIIGTVMARDPD-SISSPIRFSLDRHTDLDRIFNIHSGNGSLYTS 444
+Y +V ED+ GT+I + A DPD S +R+SL H + + F++ +G++
Sbjct: 929 PPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGN--FDVDKLSGAVRIV 986
Query: 445 KPLDRELSQWHNLTVIAAEINNPKETTRVA-VFVRILDVNDN--APQFAVFYDT-FVCEN 500
+ LD E Q +NLTV A + P + V V ++DVN+N P F+ F + V E+
Sbjct: 987 QQLDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKED 1046
Query: 501 ARPGQLIQTISAVDKDDPLGGQ 522
A G L+ T+SA D+D G+
Sbjct: 1047 APVGSLVMTVSAHDEDARRDGE 1068
Score = 160 bits (404), Expect = 6e-39
Identities = 137/497 (27%), Positives = 234/497 (47%), Gaps = 30/497 (6%)
Query: 102 FIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFP 161
F I+ TG I+ +D E Y L +A + T E + ++ DINDN P F
Sbjct: 2227 FTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAHAEVFVDIIVD--DINDNPPVFA 2284
Query: 162 EEIYTASVPEMSVVGTSVVQVTATDAD-DPSYGNSARVIYSILQGQPYFSVEPETGIIRT 220
++ Y ++ E SV+GTSVVQV ATD+D +P+ G S ++ + + +F V+ TG+I +
Sbjct: 2285 QQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSKSHDHFHVDSSTGLI-S 2343
Query: 221 ALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLE 280
L ++ E Q+ + ++A D G M LS V + +TD+NDNPP F Q R+ E
Sbjct: 2344 LLRTLDYEQSRQHTIFVRAVD--GGMPTLSSDVIVTVDVTDLNDNPPLFEQQIYEARISE 2401
Query: 281 SSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYES 340
+P G + VKA DAD+ +++Y I+ G+ F I D+ GIIT+ +
Sbjct: 2402 HAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHKHFVI----DSATGIITLSNLHRHAL 2457
Query: 341 RRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVD-EPPVFSRSSYLFEVHEDIEV 399
+ Y+L + + G F+ +T V +++ + P F ++ Y E+ E+ +
Sbjct: 2458 KPFYSLNLSVSD----------GVFRSSTQVHVTVIGGNLHSPAFLQNEYEVELAENAPL 2507
Query: 400 GTIIGTVMARDPDS-ISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLT 458
T++ V D DS I + + + DR + + G ++T + LDRE ++
Sbjct: 2508 HTLVMEVKTTDGDSGIYGHVTYHIVNDFAKDRFY--INERGQIFTLEKLDRETPAEKVIS 2565
Query: 459 VIAAEINNPKETTRVAVFVRILDVNDNAPQF-AVFYDTFVCENARPGQLIQTISAVDKDD 517
V + + V V + D NDNAPQF A Y+ + +A G + + A D D+
Sbjct: 2566 VRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVKVLASDADE 2625
Query: 518 PLGGQKFFFSLAAVNPNFTVQDNED--NTARILTRKNGFNRHEISTYLLPVVISDNDYPI 575
G + A + +V++N + + ++T K E + V DN P
Sbjct: 2626 ---GSNADITYAIEADSESVKENLEINKLSGVITTKESLIGLENEFFTFFVRAVDNGSPS 2682
Query: 576 QSSTGTLTIRVCACDSQ 592
+ S + +++ + Q
Sbjct: 2683 KESVVLVYVKILPPEMQ 2699
Score = 142 bits (359), Expect = 9e-34
Identities = 143/518 (27%), Positives = 233/518 (44%), Gaps = 37/518 (7%)
Query: 81 DQDKGD-GSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRP 139
D D D L+Y + F+ID TG I + K FY+L +++ R
Sbjct: 2416 DADSSDIDKLQYSILSGNDHKHFVIDSATGIITLSNLHRHALKPFYSLNL-SVSDGVFRS 2474
Query: 140 VEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGN-SARV 198
++ + + N + P F + Y + E + + T V++V TD D YG+ + +
Sbjct: 2475 ---STQVHVTVIGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGHVTYHI 2531
Query: 199 IYSILQGQPYFSVEPETGIIRTALPNMNRENREQ--YQVVIQAKDMGGQMGGLSGTTTVN 256
+ + + Y + E G I T L ++RE + V + AKD GG++ TVN
Sbjct: 2532 VNDFAKDRFYIN---ERGQIFT-LEKLDRETPAEKVISVRLMAKDAGGKVA----FCTVN 2583
Query: 257 ITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDM 316
+ LTD NDN P+F + + S+ GT++ V A+DAD G NA++ Y I+ D +
Sbjct: 2584 VILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVKVLASDADEGSNADITY-AIEADSESV 2642
Query: 317 FDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTI---VKI 373
+ + E + G+IT K+ L +T V A + P K++ + VKI
Sbjct: 2643 KENL-EINKLSGVITTKESLIGLENEFFTFFVRAVDNG--------SPSKESVVLVYVKI 2693
Query: 374 SIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFN 433
++ + P FS Y F V ED+ +GT I + A ++ + ++ D F
Sbjct: 2694 LPPEM-QLPKFSEPFYTFTVSEDVPIGTEIDLIRAEHSGTVLYSLVKGNTPESNRDESFV 2752
Query: 434 IHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKE-TTRVAVFVRILDVNDNAPQF-AV 491
I +G L K LD E ++W+ +++A + E V V +++ D NDN+P F +
Sbjct: 2753 IDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFESS 2812
Query: 492 FYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDNEDN--TARILT 549
Y+ F+ EN G + I A D D GQ +SL ++ N T I T
Sbjct: 2813 PYEAFIVENLPGGSRVIQIRASDADSGTNGQ-VMYSLDQSQSVEVIESFAINMETGWITT 2871
Query: 550 RKNGFNRHEISTYLLPVVISDNDYPIQ-SSTGTLTIRV 586
K + + Y + VV SD+ IQ SST + + V
Sbjct: 2872 LKE-LDHEKRDNYQIKVVASDHGEKIQLSSTAIVDVTV 2908
Score = 142 bits (358), Expect = 1e-33
Identities = 123/438 (28%), Positives = 204/438 (46%), Gaps = 41/438 (9%)
Query: 89 LKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVI 148
L + ++G + F +D+ TG I + +D E+K+ Y L +A + T ++ I
Sbjct: 1389 LWFDITGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTIL----TQVFI 1444
Query: 149 KIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP- 207
K+ D ND+ P F Y +PE + T ++Q++A D D+ + ++IY++ +
Sbjct: 1445 KVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEKN-----KLIYTLQSSRDP 1499
Query: 208 ----YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVN 263
F ++P TG + T+ ++ E Q+ + + +D + VN++ D N
Sbjct: 1500 LSLKKFRLDPATGSLYTS-EKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNVS--DTN 1556
Query: 264 DNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEK 323
D+ P F ++ RV ES+ VG+ + V A D D GKNAEV Y I G+ + F I
Sbjct: 1557 DHAPWFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNSFMI---- 1612
Query: 324 DTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDE-PP 382
D G I K LD ++ Y L V+A + P + T V+I + D P
Sbjct: 1613 DPVLGSIKTAKELDRSNQAEYDLMVKATDKGSP-------PMSEITSVRIFVTIADNASP 1665
Query: 383 VFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLY 442
F+ Y E+ E + +G+ +G V A S+ I+ D +T F+I+ +G++
Sbjct: 1666 KFTSKEYSVELSETVSIGSFVGMVTAHSQSSVVYEIK---DGNT--GDAFDINPHSGTII 1720
Query: 443 TSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQF-AVFYDTFVCENA 501
T K LD E + T+I N +T V V + D NDNAP F Y + E+A
Sbjct: 1721 TQKALDFETLPIY--TLIIQGTNMAGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESA 1778
Query: 502 RPGQLIQTISAVDKDDPL 519
I ++ D++ PL
Sbjct: 1779 S----INSVVLTDRNVPL 1792
Score = 140 bits (352), Expect = 6e-33
Identities = 136/512 (26%), Positives = 226/512 (44%), Gaps = 46/512 (8%)
Query: 88 SLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFV 147
S+ Y + G F I+ +G I + +D E YTL Q N L + +
Sbjct: 1696 SVVYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGTNMAGL---STNTTVL 1752
Query: 148 IKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQ-------VTATDADDPSYGNSARVIY 200
+ + D NDN P F + YT + E + + + V+ + A DAD S +A ++Y
Sbjct: 1753 VHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDS---NALLVY 1809
Query: 201 SILQGQ--PYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNIT 258
I++ YF+++ TG I T L +++ E + +Q DMG V +
Sbjct: 1810 HIVEPSVHTYFAIDSSTGAIHTVL-SLDYEETSIFHFTVQVHDMGTPRLFAEYAANVTVH 1868
Query: 259 LTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFD 318
+ D+ND PP F + +L + G + +V ATDAD+ +++ Y I +G+ + F
Sbjct: 1869 VIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSITEGNIGEKFS 1928
Query: 319 IVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDV 378
+ D + G +TV+ SR Y L V A + G F T VKI++++
Sbjct: 1929 M----DYKTGALTVQNTTQLRSR--YELTVRASD----------GRFAGLTSVKINVKES 1972
Query: 379 DEPPV-FSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRH-TDLDRIFNIHS 436
E + F++ Y V E+ + + A I +PI L H + DR F I
Sbjct: 1973 KESHLKFTQDVYSAVVKENSTEAETLAVITA-----IGNPINEPLFYHILNPDRRFKISR 2027
Query: 437 GNGSLYTS-KPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFA-VFYD 494
+G L T+ P DRE + ++ V E + P V V V + D NDNAP F + Y
Sbjct: 2028 TSGVLSTTGTPFDREQQEAFDVVVEVTEEHKPSAVAHVVVKVIVEDQNDNAPVFVNLPYY 2087
Query: 495 TFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGF 554
V + G +I+ ++AVD+D G+ ++ L + +F + + + + +
Sbjct: 2088 AVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYY-LKEHHEHFQIGPLGEISLKKQFELDTL 2146
Query: 555 NRHEISTYLLPVVISDNDYPIQSSTGTLTIRV 586
N+ YL+ VV D P S+ + I V
Sbjct: 2147 NKE----YLVTVVAKDGGNPAFSAEVIVPITV 2174
Score = 124 bits (310), Expect = 4e-28
Identities = 139/543 (25%), Positives = 225/543 (41%), Gaps = 72/543 (13%)
Query: 102 FIIDEKTGDIHATRRIDRE-EKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTF 160
F ID TG + + +D E YTLR +A + E E I ++++NDN P F
Sbjct: 510 FAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDNTPLF 569
Query: 161 PEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP--YFSVEPETGII 218
+ ++P VG + V+A DAD+ V Y I G +FS+ P +G++
Sbjct: 570 EKINCEGTIPRDLGVGEQITTVSAIDADELQL-----VQYQIEAGNELDFFSLNPNSGVL 624
Query: 219 RTA-----------------------------------------LPNMNRENREQYQVVI 237
L N+ E +++
Sbjct: 625 SLKRSLMDGLGAKVSFHSLRITATDGENFATPLYINITVAASHKLVNLQCEETGVAKMLA 684
Query: 238 QAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNT-IHLRVLESSPVGTAIGSVKATDA 296
+ ++ + VN + P+F ++V E+ PVG+++ + +TD
Sbjct: 685 EKLLQANKLHNQGEVEDIFFDSHSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDL 744
Query: 297 DTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVD 356
DTG N ++ Y + G+ F I D + G++ + PLD E+ YTL + + +
Sbjct: 745 DTGFNGKLVYAVSGGNEDSCFMI----DMETGMLKILSPLDRETTDKYTLNITVYDLGIP 800
Query: 357 PRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPD-SIS 415
+ + + + ++ D PP F + SY EV ED EV + I V A D D +
Sbjct: 801 QKAAW------RLLHVVVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPN 854
Query: 416 SPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAE--INNPKETTRV 473
+ +S+ TD F+I S G + ++PLDREL H+L + A + P+ + V
Sbjct: 855 GHVTYSIVTDTD---TFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQAREEPQLFSTV 911
Query: 474 AVFVRILDVNDNAPQF-AVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVN 532
V V + DVNDN P F Y V E+ G +I + A D D GQ + L
Sbjct: 912 VVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGE 971
Query: 533 PNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQ 592
NF V D RI+ + + F + ++ Y L V D P+ S + T + V D
Sbjct: 972 GNFDV-DKLSGAVRIVQQLD-FEKKQV--YNLTVRAKDKGKPV-SLSSTCYVEVEVVDVN 1026
Query: 593 GNM 595
N+
Sbjct: 1027 ENL 1029
Score = 120 bits (301), Expect = 5e-27
Identities = 101/385 (26%), Positives = 177/385 (45%), Gaps = 32/385 (8%)
Query: 144 SEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSIL 203
+E ++ I +N P F + Y+A + E V + VV V A + +V YSI
Sbjct: 2166 AEVIVPITVMNKAMPVFEKPFYSAEIAESIQVHSPVVHVQANSPE------GLKVFYSIT 2219
Query: 204 QGQPY--FSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTD 261
G P+ F++ TG+I P ++ E Y++ I+A D + G V+I + D
Sbjct: 2220 DGDPFSQFTINFNTGVINVIAP-LDFEAHPAYKLSIRATD---SLTGAHAEVFVDIIVDD 2275
Query: 262 VNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGT--DMFDI 319
+NDNPP F Q + + + E+S +GT++ V+ATD+D+ N + Y++ D F +
Sbjct: 2276 INDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSKSHDHFHV 2335
Query: 320 VTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDV- 378
D+ G+I++ + LDYE R +T+ V A + + IV + + D+
Sbjct: 2336 ----DSSTGLISLLRTLDYEQSRQHTIFVRAVDGG-------MPTLSSDVIVTVDVTDLN 2384
Query: 379 DEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSIS-SPIRFSLDRHTDLDRIFNIHSG 437
D PP+F + Y + E G + V A D DS +++S+ D + F I S
Sbjct: 2385 DNPPLFEQQIYEARISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSGND-HKHFVIDSA 2443
Query: 438 NGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAV-FYDTF 496
G + S L +++L + +++ + V V ++ N ++P F Y+
Sbjct: 2444 TGIITLSNLHRHALKPFYSLNL---SVSDGVFRSSTQVHVTVIGGNLHSPAFLQNEYEVE 2500
Query: 497 VCENARPGQLIQTISAVDKDDPLGG 521
+ ENA L+ + D D + G
Sbjct: 2501 LAENAPLHTLVMEVKTTDGDSGIYG 2525
Score = 106 bits (265), Expect = 7e-23
Identities = 115/477 (24%), Positives = 205/477 (42%), Gaps = 35/477 (7%)
Query: 114 TRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMS 173
T ++RE K YTL +A+ + T VE ++ +++ D ND P F Y+ S+PE +
Sbjct: 105 TAILNREVKDHYTLIVKALEKNT--NVEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENT 162
Query: 174 VVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENREQY 233
+ TS+ +V+ATDAD G + YS F++ P +G+I ++ + Y
Sbjct: 163 AIRTSIARVSATDAD---IGTNGEFYYSFKDRTDMFAIHPTSGVI-VLTGRLDYLETKLY 218
Query: 234 QVVIQAKDMGGQMGGLSGTTT---VNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGS 290
++ I A D G ++ G SG ++ + + + N+ P T+ L+ P A
Sbjct: 219 EMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRDP---AYAI 275
Query: 291 VKATDADTGKNAEV-EYRIIDGDGTDMFDIVTE-KDTQEGIITVKKPLDYESRRL-YTLK 347
V D D G N ++ I+ GD F V ++E + +D++S Y L
Sbjct: 276 VTVDDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGGIDWDSHPFGYNLT 335
Query: 348 VEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPV-FSRSSYLFEVHEDIEVGTIIGTV 406
++A++ P+ F ++ ++ PV F + Y E+ E T + V
Sbjct: 336 LQAKDKGTPPQ------FSSVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPVVMV 389
Query: 407 MARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINN 466
A S +R+ + + T F+++ G + +P+ R+ + L V ++
Sbjct: 390 KA---IPAYSHLRY-VFKSTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSD--- 442
Query: 467 PKETTRVAVFVRILDVNDNAPQFA-VFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFF 525
K +T+ V V++L N N P+F Y EN G + ++SAVD D+ G+ +
Sbjct: 443 RKASTK--VLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDE---GENGY 497
Query: 526 FSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTL 582
+ + N N + T + T +N Y L + SD P + L
Sbjct: 498 VTYSIANLNHVPFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEVL 554
Score = 93.2 bits (230), Expect = 8e-19
Identities = 108/472 (22%), Positives = 193/472 (40%), Gaps = 63/472 (13%)
Query: 89 LKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVI 148
L+Y+ F ++ TG I + R++ A + L +R+ ++ ++
Sbjct: 398 LRYVFKSTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSDRKA------STKVLV 451
Query: 149 KIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQ-GQP 207
K+ N N P F + Y A+ E +GT+V+ ++A D D+ G + V YSI
Sbjct: 452 KVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDE---GENGYVTYSIANLNHV 508
Query: 208 YFSVEPETGIIRTALPNMNRENREQ-YQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNP 266
F+++ TG + T+ N++ E + Y + I+A D G ITL ++NDN
Sbjct: 509 PFAIDHFTGAVSTS-ENLDYELMPRVYTLRIRASDWGLPY-RREVEVLATITLNNLNDNT 566
Query: 267 PRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQ 326
P F + + VG I +V A DAD + V+Y+I G+ D F + +
Sbjct: 567 PLFEKINCEGTIPRDLGVGEQITTVSAIDAD--ELQLVQYQIEAGNELDFFSL----NPN 620
Query: 327 EGIITVKKPL-DYESRRL--YTLKVEAEN--THVDPRFYYLGPFKDTTIVKISIEDVDEP 381
G++++K+ L D ++ ++L++ A + P + + +V + E+
Sbjct: 621 SGVLSLKRSLMDGLGAKVSFHSLRITATDGENFATPLYINITVAASHKLVNLQCEETGVA 680
Query: 382 PVFSR-------------------SSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSL 422
+ + S+ H T+ + ++ + S + F
Sbjct: 681 KMLAEKLLQANKLHNQGEVEDIFFDSHSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFM- 739
Query: 423 DRHTDLDRIFN------IHSGN-----------GSLYTSKPLDRELSQWHNLTVIAAEIN 465
TDLD FN + GN G L PLDRE + + L + ++
Sbjct: 740 -NSTDLDTGFNGKLVYAVSGGNEDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLG 798
Query: 466 NPKETTRVAVFVRILDVNDNAPQF-AVFYDTFVCENARPGQLIQTISAVDKD 516
P++ + V ++D NDN P+F Y V E+ I + A DKD
Sbjct: 799 IPQKAAWRLLHVVVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKD 850
Score = 90.9 bits (224), Expect = 4e-18
Identities = 91/366 (24%), Positives = 160/366 (43%), Gaps = 40/366 (10%)
Query: 111 IHATRRIDREEKAF-YTLRAQAINRRTLRPVEPESEFVIKIH----DINDNEPTFPEEIY 165
+ A ID + F Y L QA ++ T P+ V IH F +++Y
Sbjct: 317 VKAIGGIDWDSHPFGYNLTLQAKDKGT----PPQFSSVKVIHVTSPQFKAGPVKFEKDVY 372
Query: 166 TASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNM 225
A + E + T VV V A P+Y + R ++ G+ FS+ TG+I P +
Sbjct: 373 RAEISEFAPPNTPVVMVKAI----PAYSH-LRYVFKSTPGKAKFSLNYNTGLISILEP-V 426
Query: 226 NRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVG 285
R+ +++ + D +T V + + N NPP F Q E+ P+G
Sbjct: 427 KRQQAAHFELEVTTSDR-------KASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIG 479
Query: 286 TAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYE-SRRLY 344
T + S+ A D D G+N V Y I ++ + D G ++ + LDYE R+Y
Sbjct: 480 TTVMSLSAVDPDEGENGYVTYSI-----ANLNHVPFAIDHFTGAVSTSENLDYELMPRVY 534
Query: 345 TLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDV-DEPPVFSRSSYLFEVHEDIEVGTII 403
TL++ A + + R + + I++ ++ D P+F + + + D+ VG I
Sbjct: 535 TLRIRASDWGLPYR------REVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQI 588
Query: 404 GTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELS---QWHNLTVI 460
TV A D D + +++ ++ +LD F+++ +G L + L L +H+L +
Sbjct: 589 TTVSAIDADELQL-VQYQIEAGNELD-FFSLNPNSGVLSLKRSLMDGLGAKVSFHSLRIT 646
Query: 461 AAEINN 466
A + N
Sbjct: 647 ATDGEN 652
Score = 73.2 bits (178), Expect = 9e-13
Identities = 105/462 (22%), Positives = 191/462 (41%), Gaps = 63/462 (13%)
Query: 101 LFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTL----RPVEPESEFVIKIHDINDN 156
+F I +G I T R+D E Y + A +R + ++ + I N+
Sbjct: 194 MFAIHPTSGVIVLTGRLDYLETKLYEMEILAADRGMKLYGSSGISSMAKLTVHIEQANEC 253
Query: 157 EPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQG---QPYFSVEP 213
P T S E+ + VT D D + G+ A + SI+ G Q + +V
Sbjct: 254 APVITA--VTLSPSELDRDPAYAI-VTVDDCDQGANGDIASL--SIVAGDLLQQFRTVRS 308
Query: 214 ETGIIRTALPNMNRENREQ----YQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRF 269
G + + + + Y + +QAKD G S +++T P +F
Sbjct: 309 FPGSKEYKVKAIGGIDWDSHPFGYNLTLQAKDKGTPPQ-FSSVKVIHVTSPQFKAGPVKF 367
Query: 270 PQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGI 329
++ + E +P T + VKA A + + Y G F + + G+
Sbjct: 368 EKDVYRAEISEFAPPNTPVVMVKAIPA----YSHLRYVFKSTPGKAKFSL----NYNTGL 419
Query: 330 ITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSY 389
I++ +P+ + + L+V + + +VK+ + PP F++++Y
Sbjct: 420 ISILEPVKRQQAAHFELEVTTSDRKASTK----------VLVKV-LGANSNPPEFTQTAY 468
Query: 390 LFEVHEDIEVGTIIGTVMARDPDSISSP-IRFSLDRHTDLDRI-FNIHSGNGSLYTSKPL 447
E++ +GT + ++ A DPD + + +S+ +L+ + F I G++ TS+ L
Sbjct: 469 KAAFDENVPIGTTVMSLSAVDPDEGENGYVTYSI---ANLNHVPFAIDHFTGAVSTSENL 525
Query: 448 DRELS-QWHNLTVIAAEINNP-KETTRVAVFVRILDVNDNAPQFAVFYDTFVCENARP-- 503
D EL + + L + A++ P + V + + ++NDN P F + CE P
Sbjct: 526 DYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDNTPLF----EKINCEGTIPRD 581
Query: 504 ---GQLIQTISAVDKDD--------PLGGQKFFFSLAAVNPN 534
G+ I T+SA+D D+ G + FFSL NPN
Sbjct: 582 LGVGEQITTVSAIDADELQLVQYQIEAGNELDFFSL---NPN 620
Score = 49.7 bits (117), Expect = 1e-05
Identities = 58/215 (26%), Positives = 97/215 (45%), Gaps = 28/215 (13%)
Query: 262 VNDNPPRFPQNTIHLRVLESSPVGTAIGS-VKATDADTGKNAEVEYRIIDGDGTDMF--- 317
+ P +F ++ V E+S T +G VK T EV Y+I+ GD ++F
Sbjct: 27 LEQTPLQFTHLEYNVTVQENSAAKTYVGHPVKMGVYITHPAWEVRYKIVSGDSENLFKAE 86
Query: 318 -----DIVTEKDTQEGIITVKKPLDYESRRLYTLKVEA--ENTHVDPRFYYLGPFKDTTI 370
D + +G T L+ E + YTL V+A +NT+V+ R T
Sbjct: 87 EYILGDFCFLRIRTKGGNTA--ILNREVKDHYTLIVKALEKNTNVEAR----------TK 134
Query: 371 VKISIEDV-DEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPD-SISSPIRFSLDRHTDL 428
V++ + D D P+FS +SY + E+ + T I V A D D + +S TD+
Sbjct: 135 VRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRTDM 194
Query: 429 DRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAE 463
F IH +G + + LD ++ + + ++AA+
Sbjct: 195 ---FAIHPTSGVIVLTGRLDYLETKLYEMEILAAD 226
>gi|221316595 cadherin 17 precursor [Homo sapiens]
Length = 832
Score = 207 bits (527), Expect = 3e-53
Identities = 164/557 (29%), Positives = 272/557 (48%), Gaps = 40/557 (7%)
Query: 102 FIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFP 161
F ID++ GDI+ T+ +DREEK Y A A + +P+ E +K+ DINDN PT P
Sbjct: 284 FSIDQE-GDIYVTQPLDREEKDAYVFYAVAKDEYG-KPLSYPLEIHVKVKDINDNPPTCP 341
Query: 162 EEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP------YFSVEPET 215
+ V E +G S+ +TA D D+ + NS + Y I++ P F ++
Sbjct: 342 SPVTVFEVQENERLGNSIGTLTAHDRDEENTANSF-LNYRIVEQTPKLPMDGLFLIQTYA 400
Query: 216 GIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTI- 274
G+++ A ++ +++ QY + I+ D V I + D+ND P F ++
Sbjct: 401 GMLQLAKQSLKKQDTPQYNLTIEVSDKD-----FKTLCFVQINVIDINDQIPIFEKSDYG 455
Query: 275 HLRVLESSPVGTAIGSVKATDAD---TGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIIT 331
+L + E + +G+ I +++ATDAD TG ++++ Y II GD + T+ T G +
Sbjct: 456 NLTLAEDTNIGSTILTIQATDADEPFTG-SSKILYHIIKGDSEGRLGVDTDPHTNTGYVI 514
Query: 332 VKKPLDYESRRLYTLKVEAENTH--VDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSY 389
+KKPLD+E+ + + +AEN V Y F T++ + DV+E P FS+ +
Sbjct: 515 IKKPLDFETAAVSNIVFKAENPEPLVFGVKYNASSFAKFTLI---VTDVNEAPQFSQHVF 571
Query: 390 LFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDR 449
+V ED+ +GT +G V A+DP+ + I +SL D I G +++ PLDR
Sbjct: 572 QAKVSEDVAIGTKVGNVTAKDPEGLD--ISYSL--RGDTRGWLKIDHVTGEIFSVAPLDR 627
Query: 450 ELSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFY-DTFVCEN-ARPGQLI 507
E + + V+A E+ ++ + ++DVNDN P+ A Y F C + PG LI
Sbjct: 628 EAGSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGSLI 687
Query: 508 QTISAVDKDDPL-GGQKFFFSL--AAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLL 564
A D D L G F FSL ++ ++ V AR+ TR F E Y++
Sbjct: 688 --FEATDDDQHLFRGPHFTFSLGSGSLQNDWEVSKINGTHARLSTRHTEFEERE---YVV 742
Query: 565 PVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIIL 624
+ I+D P +L + C+C + + + G++ G L+ LL I I+
Sbjct: 743 LIRINDGGRPPLEGIVSLPVTFCSCVEGSCFRPAGHQTGIPTVGMAVGILLTTLLVIGII 802
Query: 625 LVIVVLFAALKRQRKKE 641
L +V F +K+ + K+
Sbjct: 803 LAVV--FIRIKKDKGKD 817
Score = 145 bits (367), Expect = 1e-34
Identities = 130/454 (28%), Positives = 216/454 (47%), Gaps = 47/454 (10%)
Query: 88 SLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFV 147
++ + L+G+ +F+I E+ G ++ R +DRE ++ + L+ A++ + VE
Sbjct: 57 AVTFELTGE-TDNIFVI-EREGLLYYNRALDRETRSTHNLQVAALDANGII-VEGPVPIT 113
Query: 148 IKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP 207
IK+ DINDN PTF + Y SV + S G + V ATD DDP+ N ++ Y I+ P
Sbjct: 114 IKVKDINDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPN-GQLYYQIVIQLP 172
Query: 208 ------YFSVEPETGII---RTALPNMNRENREQYQVVIQAKDMGGQM-GGLSGTTTVNI 257
YF + +TG I R +N Y +VI KDMGGQ S TT+V+I
Sbjct: 173 MINNVMYFQINNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDI 232
Query: 258 TLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMF 317
+T+ P+ + ++E+S I + D G +Y ++D + F
Sbjct: 233 IVTENIWKAPK------PVEMVENSTDPHPIKITQVRWNDPG----AQYSLVDKEKLPRF 282
Query: 318 DIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIED 377
+ QEG I V +PLD E + Y A++ + P Y L + + ++D
Sbjct: 283 PFSID---QEGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLE-------IHVKVKD 332
Query: 378 V-DEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPD---SISSPIRFSLDRHT---DLDR 430
+ D PP +FEV E+ +G IGT+ A D D + +S + + + T +D
Sbjct: 333 INDNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDG 392
Query: 431 IFNIHSGNGSLYTSK-PLDRELSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQF 489
+F I + G L +K L ++ + +NLT+ E+++ T V + ++D+ND P F
Sbjct: 393 LFLIQTYAGMLQLAKQSLKKQDTPQYNLTI---EVSDKDFKTLCFVQINVIDINDQIPIF 449
Query: 490 --AVFYDTFVCENARPGQLIQTISAVDKDDPLGG 521
+ + + + E+ G I TI A D D+P G
Sbjct: 450 EKSDYGNLTLAEDTNIGSTILTIQATDADEPFTG 483
>gi|221316593 cadherin 17 precursor [Homo sapiens]
Length = 832
Score = 207 bits (527), Expect = 3e-53
Identities = 164/557 (29%), Positives = 272/557 (48%), Gaps = 40/557 (7%)
Query: 102 FIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFP 161
F ID++ GDI+ T+ +DREEK Y A A + +P+ E +K+ DINDN PT P
Sbjct: 284 FSIDQE-GDIYVTQPLDREEKDAYVFYAVAKDEYG-KPLSYPLEIHVKVKDINDNPPTCP 341
Query: 162 EEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP------YFSVEPET 215
+ V E +G S+ +TA D D+ + NS + Y I++ P F ++
Sbjct: 342 SPVTVFEVQENERLGNSIGTLTAHDRDEENTANSF-LNYRIVEQTPKLPMDGLFLIQTYA 400
Query: 216 GIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTI- 274
G+++ A ++ +++ QY + I+ D V I + D+ND P F ++
Sbjct: 401 GMLQLAKQSLKKQDTPQYNLTIEVSDKD-----FKTLCFVQINVIDINDQIPIFEKSDYG 455
Query: 275 HLRVLESSPVGTAIGSVKATDAD---TGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIIT 331
+L + E + +G+ I +++ATDAD TG ++++ Y II GD + T+ T G +
Sbjct: 456 NLTLAEDTNIGSTILTIQATDADEPFTG-SSKILYHIIKGDSEGRLGVDTDPHTNTGYVI 514
Query: 332 VKKPLDYESRRLYTLKVEAENTH--VDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSY 389
+KKPLD+E+ + + +AEN V Y F T++ + DV+E P FS+ +
Sbjct: 515 IKKPLDFETAAVSNIVFKAENPEPLVFGVKYNASSFAKFTLI---VTDVNEAPQFSQHVF 571
Query: 390 LFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDR 449
+V ED+ +GT +G V A+DP+ + I +SL D I G +++ PLDR
Sbjct: 572 QAKVSEDVAIGTKVGNVTAKDPEGLD--ISYSL--RGDTRGWLKIDHVTGEIFSVAPLDR 627
Query: 450 ELSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFY-DTFVCEN-ARPGQLI 507
E + + V+A E+ ++ + ++DVNDN P+ A Y F C + PG LI
Sbjct: 628 EAGSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGSLI 687
Query: 508 QTISAVDKDDPL-GGQKFFFSL--AAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLL 564
A D D L G F FSL ++ ++ V AR+ TR F E Y++
Sbjct: 688 --FEATDDDQHLFRGPHFTFSLGSGSLQNDWEVSKINGTHARLSTRHTEFEERE---YVV 742
Query: 565 PVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIIL 624
+ I+D P +L + C+C + + + G++ G L+ LL I I+
Sbjct: 743 LIRINDGGRPPLEGIVSLPVTFCSCVEGSCFRPAGHQTGIPTVGMAVGILLTTLLVIGII 802
Query: 625 LVIVVLFAALKRQRKKE 641
L +V F +K+ + K+
Sbjct: 803 LAVV--FIRIKKDKGKD 817
Score = 145 bits (367), Expect = 1e-34
Identities = 130/454 (28%), Positives = 216/454 (47%), Gaps = 47/454 (10%)
Query: 88 SLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFV 147
++ + L+G+ +F+I E+ G ++ R +DRE ++ + L+ A++ + VE
Sbjct: 57 AVTFELTGE-TDNIFVI-EREGLLYYNRALDRETRSTHNLQVAALDANGII-VEGPVPIT 113
Query: 148 IKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP 207
IK+ DINDN PTF + Y SV + S G + V ATD DDP+ N ++ Y I+ P
Sbjct: 114 IKVKDINDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPN-GQLYYQIVIQLP 172
Query: 208 ------YFSVEPETGII---RTALPNMNRENREQYQVVIQAKDMGGQM-GGLSGTTTVNI 257
YF + +TG I R +N Y +VI KDMGGQ S TT+V+I
Sbjct: 173 MINNVMYFQINNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDI 232
Query: 258 TLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMF 317
+T+ P+ + ++E+S I + D G +Y ++D + F
Sbjct: 233 IVTENIWKAPK------PVEMVENSTDPHPIKITQVRWNDPG----AQYSLVDKEKLPRF 282
Query: 318 DIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIED 377
+ QEG I V +PLD E + Y A++ + P Y L + + ++D
Sbjct: 283 PFSID---QEGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLE-------IHVKVKD 332
Query: 378 V-DEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPD---SISSPIRFSLDRHT---DLDR 430
+ D PP +FEV E+ +G IGT+ A D D + +S + + + T +D
Sbjct: 333 INDNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDG 392
Query: 431 IFNIHSGNGSLYTSK-PLDRELSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQF 489
+F I + G L +K L ++ + +NLT+ E+++ T V + ++D+ND P F
Sbjct: 393 LFLIQTYAGMLQLAKQSLKKQDTPQYNLTI---EVSDKDFKTLCFVQINVIDINDQIPIF 449
Query: 490 --AVFYDTFVCENARPGQLIQTISAVDKDDPLGG 521
+ + + + E+ G I TI A D D+P G
Sbjct: 450 EKSDYGNLTLAEDTNIGSTILTIQATDADEPFTG 483
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.136 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,686,775
Number of Sequences: 37866
Number of extensions: 1428363
Number of successful extensions: 8681
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 195
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 3250
Number of HSP's gapped (non-prelim): 930
length of query: 788
length of database: 18,247,518
effective HSP length: 110
effective length of query: 678
effective length of database: 14,082,258
effective search space: 9547770924
effective search space used: 9547770924
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.