Guide to the Human Genome
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Search of human proteins with 157426860

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157426860 transmembrane channel-like 5 isoform a [Homo
sapiens]
         (1006 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens]   2075   0.0  
gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens]   1852   0.0  
gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens]    1327   0.0  
gi|187608784 transmembrane channel-like 6 [Homo sapiens]              402   e-112
gi|187608791 transmembrane channel-like 6 [Homo sapiens]              402   e-112
gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens]    234   4e-61
gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens]    228   2e-59
gi|23943900 transmembrane channel-like 8 [Homo sapiens]               197   4e-50
gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens]     182   2e-45
gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens]    182   2e-45
gi|21071070 transmembrane channel-like 1 [Homo sapiens]               138   3e-32
gi|94536852 transmembrane cochlear-expressed protein 2 [Homo sap...   134   4e-31
gi|122937502 transmembrane channel-like 3 [Homo sapiens]              103   6e-22
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]        53   2e-06
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    51   5e-06
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    50   1e-05
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    50   1e-05
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    50   1e-05
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...    46   2e-04
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...    46   2e-04
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...    46   2e-04
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...    46   2e-04
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho...    45   3e-04
gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho...    45   3e-04
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho...    45   3e-04
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]     45   3e-04
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      44   6e-04
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       44   8e-04
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     44   8e-04
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     44   8e-04

>gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens]
          Length = 1006

 Score = 2075 bits (5375), Expect = 0.0
 Identities = 1006/1006 (100%), Positives = 1006/1006 (100%)

Query: 1    MSAYYRNNWSEEDPDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASR 60
            MSAYYRNNWSEEDPDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASR
Sbjct: 1    MSAYYRNNWSEEDPDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASR 60

Query: 61   TRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHR 120
            TRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHR
Sbjct: 61   TRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHR 120

Query: 121  ASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLN 180
            ASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLN
Sbjct: 121  ASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLN 180

Query: 181  HPGSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLPSTWRE 240
            HPGSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLPSTWRE
Sbjct: 181  HPGSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLPSTWRE 240

Query: 241  PDYSDAENGHDYGSSETPKMTRGVLSRTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMAS 300
            PDYSDAENGHDYGSSETPKMTRGVLSRTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMAS
Sbjct: 241  PDYSDAENGHDYGSSETPKMTRGVLSRTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMAS 300

Query: 301  MEMANSYGHSLPGAPGSGYVNPAYVGESGPVHAYGNPPLSECDWHKSPQGQKLIASLIPM 360
            MEMANSYGHSLPGAPGSGYVNPAYVGESGPVHAYGNPPLSECDWHKSPQGQKLIASLIPM
Sbjct: 301  MEMANSYGHSLPGAPGSGYVNPAYVGESGPVHAYGNPPLSECDWHKSPQGQKLIASLIPM 360

Query: 361  TSRDRIKAIRNQPRTMEEKRNLRKIVDKEKSKQTHRILQLNCCIQCLNSISRAYRRSKNS 420
            TSRDRIKAIRNQPRTMEEKRNLRKIVDKEKSKQTHRILQLNCCIQCLNSISRAYRRSKNS
Sbjct: 361  TSRDRIKAIRNQPRTMEEKRNLRKIVDKEKSKQTHRILQLNCCIQCLNSISRAYRRSKNS 420

Query: 421  LSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIPQFTVAK 480
            LSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIPQFTVAK
Sbjct: 421  LSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIPQFTVAK 480

Query: 481  KNTLQFTGLEFFTGVGYFRDTVMYYGFYTNSTIQHGNSGASYNMQLAYIFTIGACLTTCF 540
            KNTLQFTGLEFFTGVGYFRDTVMYYGFYTNSTIQHGNSGASYNMQLAYIFTIGACLTTCF
Sbjct: 481  KNTLQFTGLEFFTGVGYFRDTVMYYGFYTNSTIQHGNSGASYNMQLAYIFTIGACLTTCF 540

Query: 541  FSLLFSMAKYFRNNFINPHIYSGGITKLIFCWDFTVTHEKAVKLKQKNLSTEIRENLSEL 600
            FSLLFSMAKYFRNNFINPHIYSGGITKLIFCWDFTVTHEKAVKLKQKNLSTEIRENLSEL
Sbjct: 541  FSLLFSMAKYFRNNFINPHIYSGGITKLIFCWDFTVTHEKAVKLKQKNLSTEIRENLSEL 600

Query: 601  RQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYNLEFLKTHSNPGAVLLL 660
            RQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYNLEFLKTHSNPGAVLLL
Sbjct: 601  RQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYNLEFLKTHSNPGAVLLL 660

Query: 661  PFVVSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNTVALS 720
            PFVVSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNTVALS
Sbjct: 661  PFVVSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNTVALS 720

Query: 721  GEECWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRIIGMQLITSLGLQEFDIARNVLEL 780
            GEECWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRIIGMQLITSLGLQEFDIARNVLEL
Sbjct: 721  GEECWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRIIGMQLITSLGLQEFDIARNVLEL 780

Query: 781  IYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLL 840
            IYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLL
Sbjct: 781  IYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLL 840

Query: 841  FFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPGYLWVVWIYRN 900
            FFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPGYLWVVWIYRN
Sbjct: 841  FFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPGYLWVVWIYRN 900

Query: 901  LIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIKLQDM 960
            LIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIKLQDM
Sbjct: 901  LIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIKLQDM 960

Query: 961  EKKANPSSLVLERREVEQQGFLHLGEHDGSLDLRSRRSVQEGNPRA 1006
            EKKANPSSLVLERREVEQQGFLHLGEHDGSLDLRSRRSVQEGNPRA
Sbjct: 961  EKKANPSSLVLERREVEQQGFLHLGEHDGSLDLRSRRSVQEGNPRA 1006


>gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens]
          Length = 948

 Score = 1852 bits (4796), Expect = 0.0
 Identities = 920/1006 (91%), Positives = 929/1006 (92%), Gaps = 58/1006 (5%)

Query: 1    MSAYYRNNWSEEDPDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASR 60
            MSAYYRNNWSEEDPDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASR
Sbjct: 1    MSAYYRNNWSEEDPDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASR 60

Query: 61   TRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHR 120
            TRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHR
Sbjct: 61   TRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHR 120

Query: 121  ASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLN 180
            ASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLN
Sbjct: 121  ASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLN 180

Query: 181  HPGSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLPSTWRE 240
            HPGSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLPSTWRE
Sbjct: 181  HPGSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLPSTWRE 240

Query: 241  PDYSDAENGHDYGSSETPKMTRGVLSRTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMAS 300
            PDYSDAENGHDYGSSETPKMTRGVLSRTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMAS
Sbjct: 241  PDYSDAENGHDYGSSETPKMTRGVLSRTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMAS 300

Query: 301  MEMANSYGHSLPGAPGSGYVNPAYVGESGPVHAYGNPPLSECDWHKSPQGQKLIASLIPM 360
            MEMANSYGHSLPGAPGSGYVNPAYVGESGPVHAYGNPPLSECDWHKSPQGQKLIASLIPM
Sbjct: 301  MEMANSYGHSLPGAPGSGYVNPAYVGESGPVHAYGNPPLSECDWHKSPQGQKLIASLIPM 360

Query: 361  TSRDRIKAIRNQPRTMEEKRNLRKIVDKEKSKQTHRILQLNCCIQCLNSISRAYRRSKNS 420
            TSRDRIKAIRNQPRTMEEKRNLRKIVDKEKSKQTHRILQLNCCIQCLNSISRAYRRSKNS
Sbjct: 361  TSRDRIKAIRNQPRTMEEKRNLRKIVDKEKSKQTHRILQLNCCIQCLNSISRAYRRSKNS 420

Query: 421  LSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIPQFTVAK 480
            LSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIPQFTVAK
Sbjct: 421  LSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIPQFTVAK 480

Query: 481  KNTLQFTGLEFFTGVGYFRDTVMYYGFYTNSTIQHGNSGASYNMQLAYIFTIGACLTTCF 540
            KNTLQFTGLEFFTGVGYFRDTVMYYGFYTNSTIQHGNSGASYNMQLAYIFTIGACLTTCF
Sbjct: 481  KNTLQFTGLEFFTGVGYFRDTVMYYGFYTNSTIQHGNSGASYNMQLAYIFTIGACLTTCF 540

Query: 541  FSLLFSMAKYFRNNFINPHIYSGGITKLIFCWDFTVTHEKAVKLKQKNLSTEIRENLSEL 600
            FSLLFSMAKYFRNNFINPHIYSGGITKLIFCWDFTVTHEKAVKLKQKNLSTEIRENLSEL
Sbjct: 541  FSLLFSMAKYFRNNFINPHIYSGGITKLIFCWDFTVTHEKAVKLKQKNLSTEIRENLSEL 600

Query: 601  RQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYNLEFLKTHSNPGAVLLL 660
            RQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYNLEFLKTHSNPGAVLLL
Sbjct: 601  RQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYNLEFLKTHSNPGAVLLL 660

Query: 661  PFVVSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNTVALS 720
            PFVVSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNTVALS
Sbjct: 661  PFVVSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNTVALS 720

Query: 721  GEECWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRIIGMQLITSLGLQEFDIARNVLEL 780
            GEECWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRIIGMQLITSLGLQEFDIARNVLEL
Sbjct: 721  GEECWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRIIGMQLITSLGLQEFDIARNVLEL 780

Query: 781  IYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLL 840
            IYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLL
Sbjct: 781  IYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLL 840

Query: 841  FFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPGYLWVVWIYRN 900
            FFPSFTGVLCTLAITIWR+               I  +Y             W +   R 
Sbjct: 841  FFPSFTGVLCTLAITIWRI---------------ITYLY-------------WQITEGRK 872

Query: 901  LIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIKLQDM 960
                           ++I  L+ QI    K  + L+ + I               KLQDM
Sbjct: 873  ---------------IMIRLLHEQIINEGKDKMFLIEKLI---------------KLQDM 902

Query: 961  EKKANPSSLVLERREVEQQGFLHLGEHDGSLDLRSRRSVQEGNPRA 1006
            EKKANPSSLVLERREVEQQGFLHLGEHDGSLDLRSRRSVQEGNPRA
Sbjct: 903  EKKANPSSLVLERREVEQQGFLHLGEHDGSLDLRSRRSVQEGNPRA 948


>gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens]
          Length = 760

 Score = 1327 bits (3434), Expect = 0.0
 Identities = 659/662 (99%), Positives = 661/662 (99%)

Query: 345  HKSPQGQKLIASLIPMTSRDRIKAIRNQPRTMEEKRNLRKIVDKEKSKQTHRILQLNCCI 404
            H++ QGQKLIASLIPMTSRDRIKAIRNQPRTMEEKRNLRKIVDKEKSKQTHRILQLNCCI
Sbjct: 99   HETVQGQKLIASLIPMTSRDRIKAIRNQPRTMEEKRNLRKIVDKEKSKQTHRILQLNCCI 158

Query: 405  QCLNSISRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSF 464
            QCLNSISRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSF
Sbjct: 159  QCLNSISRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSF 218

Query: 465  ILNFSFIIIPQFTVAKKNTLQFTGLEFFTGVGYFRDTVMYYGFYTNSTIQHGNSGASYNM 524
            ILNFSFIIIPQFTVAKKNTLQFTGLEFFTGVGYFRDTVMYYGFYTNSTIQHGNSGASYNM
Sbjct: 219  ILNFSFIIIPQFTVAKKNTLQFTGLEFFTGVGYFRDTVMYYGFYTNSTIQHGNSGASYNM 278

Query: 525  QLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFCWDFTVTHEKAVKL 584
            QLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFCWDFTVTHEKAVKL
Sbjct: 279  QLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFCWDFTVTHEKAVKL 338

Query: 585  KQKNLSTEIRENLSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYN 644
            KQKNLSTEIRENLSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYN
Sbjct: 339  KQKNLSTEIRENLSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYN 398

Query: 645  LEFLKTHSNPGAVLLLPFVVSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIRNIFLKIS 704
            LEFLKTHSNPGAVLLLPFVVSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIRNIFLKIS
Sbjct: 399  LEFLKTHSNPGAVLLLPFVVSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIRNIFLKIS 458

Query: 705  IIGILCYYWLNTVALSGEECWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRIIGMQLIT 764
            IIGILCYYWLNTVALSGEECWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRIIGMQLIT
Sbjct: 459  IIGILCYYWLNTVALSGEECWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRIIGMQLIT 518

Query: 765  SLGLQEFDIARNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPS 824
            SLGLQEFDIARNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPS
Sbjct: 519  SLGLQEFDIARNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPS 578

Query: 825  KAWRASQMMTFFIFLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDT 884
            KAWRASQMMTFFIFLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDT
Sbjct: 579  KAWRASQMMTFFIFLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDT 638

Query: 885  LSTRPGYLWVVWIYRNLIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEG 944
            LSTRPGYLWVVWIYRNLIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEG
Sbjct: 639  LSTRPGYLWVVWIYRNLIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEG 698

Query: 945  KDKMFLIEKLIKLQDMEKKANPSSLVLERREVEQQGFLHLGEHDGSLDLRSRRSVQEGNP 1004
            KDKMFLIEKLIKLQDMEKKANPSSLVLERREVEQQGFLHLGEHDGSLDLRSRRSVQEGNP
Sbjct: 699  KDKMFLIEKLIKLQDMEKKANPSSLVLERREVEQQGFLHLGEHDGSLDLRSRRSVQEGNP 758

Query: 1005 RA 1006
            RA
Sbjct: 759  RA 760


>gi|187608784 transmembrane channel-like 6 [Homo sapiens]
          Length = 805

 Score =  402 bits (1033), Expect = e-112
 Identities = 233/637 (36%), Positives = 355/637 (55%), Gaps = 23/637 (3%)

Query: 353 LIASLIPMTSRDRIKAIRNQPRTMEEKRNLRKIVDKEKSK---QTHRILQLNCCIQCLNS 409
           L+  L  +    R   +R  P ++ EKR+LR+     + K   Q       +CC +   +
Sbjct: 149 LVKELQSLAVAQRDHMLRGMPLSLAEKRSLREKSRTPRGKWRGQPGSGGVCSCCGRLRYA 208

Query: 410 ISRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFS 469
              A      +L   L ++  W+  LK IGG+FG+SVLSYF FL+ LL FN    +L  +
Sbjct: 209 CVLALHSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVA 268

Query: 470 FIIIPQ--FTVAKKNTLQF-TGLEFFTGVGYFRDTVMYYGFYTNSTIQH-------GNS- 518
           FI+ PQ  F  A        TGLE  TG G F  TVMYYG Y+N+T+         G+  
Sbjct: 269 FIMGPQVAFPPALPGPAPVCTGLELLTGAGCFTHTVMYYGHYSNATLNQPCGSPLDGSQC 328

Query: 519 -----GASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-W 572
                G  YNM LAY+ T+G        +L++SMA  F  ++      SG     +FC W
Sbjct: 329 TPRVGGLPYNMPLAYLSTVGVSFFITCITLVYSMAHSFGESY-RVGSTSGIHAITVFCSW 387

Query: 573 DFTVTHEKAVKLKQKNLSTEIRENLSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIA 632
           D+ VT ++A +L+Q N+ T ++E L+E +  +S  +    L + +   + W++  G A+ 
Sbjct: 388 DYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVLGLVWLLCLGTALG 447

Query: 633 CCAAVYYLAEYNLEFLKTHSNPGAVLLLPFVVSCINLAVPCIYSMFRLVERYEMPRHEVY 692
           C  AV+  +E+ ++  +       +L+LP VV  +NL  P +  +   +E ++ P  EVY
Sbjct: 448 CAVAVHVFSEFMIQSPEAAGQEAVLLVLPLVVGLLNLGAPYLCRVLAALEPHDSPVLEVY 507

Query: 693 VLLIRNIFLKISIIGILCYYWLNT-VALSGEECWETLIGQDIYRLLLMDFVFSLVNSFLG 751
           V + RN+ LK++I+G LCY+WL   V +   +CWE  +GQ++YR L+MDFV  L+++  G
Sbjct: 508 VAICRNLILKLAILGTLCYHWLGRRVGVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLFG 567

Query: 752 EFLRRIIGMQLITSLGLQEFDIARNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYS 811
           E + RII  + +      EFDIARNVLELIY QTL W+G+ F PLLP +Q+I L ++FY 
Sbjct: 568 ELVWRIISEKKLKRRRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYV 627

Query: 812 KNISLMMNFQPPSKAWRASQMMTFFIFLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGL 871
           K  SL+ N Q P + W AS M T F+ LL FP+F G    L   +W++KPS+ CGPFR L
Sbjct: 628 KKTSLLANCQAPRRPWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTL 687

Query: 872 PLFIHSIYSWIDTL-STRPGYLWVVWIYRNLIGSVHFFFILTLIVLIITYLYWQITEGRK 930
                +   W+  L +  P   W+ W++R L+ +  F F+++ ++L + YL  Q+  G++
Sbjct: 688 DTMYEAGRVWVRHLEAAGPRVSWLPWVHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQR 747

Query: 931 IMIRLLHEQIINEGKDKMFLIEKLIKLQDMEKKANPS 967
            +I LL EQI NEG+DK+FLI KL  + + +++   S
Sbjct: 748 KVICLLKEQISNEGEDKIFLINKLHSIYERKEREERS 784


>gi|187608791 transmembrane channel-like 6 [Homo sapiens]
          Length = 805

 Score =  402 bits (1033), Expect = e-112
 Identities = 233/637 (36%), Positives = 355/637 (55%), Gaps = 23/637 (3%)

Query: 353 LIASLIPMTSRDRIKAIRNQPRTMEEKRNLRKIVDKEKSK---QTHRILQLNCCIQCLNS 409
           L+  L  +    R   +R  P ++ EKR+LR+     + K   Q       +CC +   +
Sbjct: 149 LVKELQSLAVAQRDHMLRGMPLSLAEKRSLREKSRTPRGKWRGQPGSGGVCSCCGRLRYA 208

Query: 410 ISRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFS 469
              A      +L   L ++  W+  LK IGG+FG+SVLSYF FL+ LL FN    +L  +
Sbjct: 209 CVLALHSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVA 268

Query: 470 FIIIPQ--FTVAKKNTLQF-TGLEFFTGVGYFRDTVMYYGFYTNSTIQH-------GNS- 518
           FI+ PQ  F  A        TGLE  TG G F  TVMYYG Y+N+T+         G+  
Sbjct: 269 FIMGPQVAFPPALPGPAPVCTGLELLTGAGCFTHTVMYYGHYSNATLNQPCGSPLDGSQC 328

Query: 519 -----GASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-W 572
                G  YNM LAY+ T+G        +L++SMA  F  ++      SG     +FC W
Sbjct: 329 TPRVGGLPYNMPLAYLSTVGVSFFITCITLVYSMAHSFGESY-RVGSTSGIHAITVFCSW 387

Query: 573 DFTVTHEKAVKLKQKNLSTEIRENLSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIA 632
           D+ VT ++A +L+Q N+ T ++E L+E +  +S  +    L + +   + W++  G A+ 
Sbjct: 388 DYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVLGLVWLLCLGTALG 447

Query: 633 CCAAVYYLAEYNLEFLKTHSNPGAVLLLPFVVSCINLAVPCIYSMFRLVERYEMPRHEVY 692
           C  AV+  +E+ ++  +       +L+LP VV  +NL  P +  +   +E ++ P  EVY
Sbjct: 448 CAVAVHVFSEFMIQSPEAAGQEAVLLVLPLVVGLLNLGAPYLCRVLAALEPHDSPVLEVY 507

Query: 693 VLLIRNIFLKISIIGILCYYWLNT-VALSGEECWETLIGQDIYRLLLMDFVFSLVNSFLG 751
           V + RN+ LK++I+G LCY+WL   V +   +CWE  +GQ++YR L+MDFV  L+++  G
Sbjct: 508 VAICRNLILKLAILGTLCYHWLGRRVGVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLFG 567

Query: 752 EFLRRIIGMQLITSLGLQEFDIARNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYS 811
           E + RII  + +      EFDIARNVLELIY QTL W+G+ F PLLP +Q+I L ++FY 
Sbjct: 568 ELVWRIISEKKLKRRRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYV 627

Query: 812 KNISLMMNFQPPSKAWRASQMMTFFIFLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGL 871
           K  SL+ N Q P + W AS M T F+ LL FP+F G    L   +W++KPS+ CGPFR L
Sbjct: 628 KKTSLLANCQAPRRPWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTL 687

Query: 872 PLFIHSIYSWIDTL-STRPGYLWVVWIYRNLIGSVHFFFILTLIVLIITYLYWQITEGRK 930
                +   W+  L +  P   W+ W++R L+ +  F F+++ ++L + YL  Q+  G++
Sbjct: 688 DTMYEAGRVWVRHLEAAGPRVSWLPWVHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQR 747

Query: 931 IMIRLLHEQIINEGKDKMFLIEKLIKLQDMEKKANPS 967
            +I LL EQI NEG+DK+FLI KL  + + +++   S
Sbjct: 748 KVICLLKEQISNEGEDKIFLINKLHSIYERKEREERS 784


>gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens]
          Length = 723

 Score =  234 bits (596), Expect = 4e-61
 Identities = 177/647 (27%), Positives = 308/647 (47%), Gaps = 73/647 (11%)

Query: 368 AIRNQPRTMEEKRNLRKIVDKEKSKQTHRILQLNCCIQCLNSISRAYRRSKNSLSEILNS 427
           ++RN    + EKR LR I       Q  ++  L+   Q     S++++R      E+   
Sbjct: 89  SLRNYALNISEKRRLRDI-------QETQMKYLSEWDQWKRYSSKSWKRFLEKAREMTTH 141

Query: 428 ISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFIL-----------------NFSF 470
           + LW++ ++ I GKFGT + SYF+FLR+L+  N+  F++                 N SF
Sbjct: 142 LELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSF 201

Query: 471 IIIPQFTVAKKNTL---QFTGLEFF--------TGVGYFRDTVMYYGFYTNSTIQHGNSG 519
           ++IP   + K+ T+     +GL +F        +G G+  +T ++YG YT   ++  N  
Sbjct: 202 VLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYTIDGVKFQNF- 260

Query: 520 ASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-WDFTVTH 578
            +Y++ LAY+ +  A L      ++    + F+ N I    +       IF  WDF +T+
Sbjct: 261 -TYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITN 319

Query: 579 EKAVKLKQKNLSTEIRENLSE--LRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAA 636
                LK  +L  E+R +L E  +RQ+ ++ T  + +  +S  +    +   V  AC  A
Sbjct: 320 RSMADLKHSSLRYELRADLEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYA 379

Query: 637 VYYLAEYNLEFLKTHSNPGA------VLLLP-FVVSCINLAVPCIYSMFRLVERYEMPRH 689
           +Y    ++ E +K   +         +L LP  V++  N   P I++     E Y  P  
Sbjct: 380 IYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIFAKIIRYEDYS-PGF 438

Query: 690 EVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE-------------CWETLIGQDIYRL 736
           E+ + ++R +F++++ I +L +   + +    ++             CWET +GQ++Y+L
Sbjct: 439 EIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYNQKLYPCWETQVGQEMYKL 498

Query: 737 LLMDFVFSLVNSFLGEFLRRII-----GMQLITSLGLQEFDIARNVLELIYAQTLVWIGI 791
           ++ DF+  L  +   +F R+++       +LI   G QEF I  NVL ++Y QT+ WIG 
Sbjct: 499 MIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICWIGA 558

Query: 792 FFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLLFFPSFTGVLCT 851
           FF PLLP I  +   I+FY K  SL+   +P  + +RAS    FF+ +L       ++  
Sbjct: 559 FFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGLCLAII-P 617

Query: 852 LAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPGYLWVVWIYRNLIGSVHFFFIL 911
           L I+I R+  S  CGPF         I     T+ST P  L     + + + S  F    
Sbjct: 618 LTISISRIPSSKACGPFTNFNTTWEVIPK---TVSTFPSSL---QSFIHGVTSEAFAVPF 671

Query: 912 TLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIKLQ 958
            +I+ +I + +  +    K ++  L EQ+  E +DK +LI+KL + Q
Sbjct: 672 FMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKLTEAQ 718


>gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens]
          Length = 613

 Score =  228 bits (582), Expect = 2e-59
 Identities = 166/604 (27%), Positives = 291/604 (48%), Gaps = 66/604 (10%)

Query: 411 SRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFIL---- 466
           S++++R      E+   + LW++ ++ I GKFGT + SYF+FLR+L+  N+  F++    
Sbjct: 15  SKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFML 74

Query: 467 -------------NFSFIIIPQFTVAKKNTL---QFTGLEFF--------TGVGYFRDTV 502
                        N SF++IP   + K+ T+     +GL +F        +G G+  +T 
Sbjct: 75  VLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETS 134

Query: 503 MYYGFYTNSTIQHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYS 562
           ++YG YT   ++  N   +Y++ LAY+ +  A L      ++    + F+ N I    + 
Sbjct: 135 LFYGHYTIDGVKFQNF--TYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHF 192

Query: 563 GGITKLIFC-WDFTVTHEKAVKLKQKNLSTEIRENLSE--LRQENSKLTFNQLLTRFSAY 619
                 IF  WDF +T+     LK  +L  E+R +L E  +RQ+ ++ T  + +  +S  
Sbjct: 193 QSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTSEETIRIYSLR 252

Query: 620 MVAWVVSTGVAIACCAAVYYLAEYNLEFLKTHSNPGA------VLLLP-FVVSCINLAVP 672
           +    +   V  AC  A+Y    ++ E +K   +         +L LP  V++  N   P
Sbjct: 253 LFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLANFITP 312

Query: 673 CIYSMFRLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE--------- 723
            I++     E Y  P  E+ + ++R +F++++ I +L +   + +    ++         
Sbjct: 313 MIFAKIIRYEDYS-PGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYNQ 371

Query: 724 ----CWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRII-----GMQLITSLGLQEFDIA 774
               CWET +GQ++Y+L++ DF+  L  +   +F R+++       +LI   G QEF I 
Sbjct: 372 KLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIP 431

Query: 775 RNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMT 834
            NVL ++Y QT+ WIG FF PLLP I  +   I+FY K  SL+   +P  + +RAS    
Sbjct: 432 DNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNF 491

Query: 835 FFIFLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPGYLWV 894
           FF+ +L       ++  L I+I R+  S  CGPF         I     T+ST P  L  
Sbjct: 492 FFLLVLLIGLCLAII-PLTISISRIPSSKACGPFTNFNTTWEVIPK---TVSTFPSSL-- 545

Query: 895 VWIYRNLIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKL 954
              + + + S  F     +I+ +I + +  +    K ++  L EQ+  E +DK +LI+KL
Sbjct: 546 -QSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKL 604

Query: 955 IKLQ 958
            + Q
Sbjct: 605 TEAQ 608


>gi|23943900 transmembrane channel-like 8 [Homo sapiens]
          Length = 726

 Score =  197 bits (501), Expect = 4e-50
 Identities = 153/591 (25%), Positives = 274/591 (46%), Gaps = 64/591 (10%)

Query: 415 RRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIP 474
           RR + +   +   + LW+  L  IGG FGT + SYF FLR+LL  N+ S +L  SF+++P
Sbjct: 75  RRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLP 134

Query: 475 QFTVAKKN-------TLQFTG--------LEFFTGVGY------FRDTVMYYGFYTNSTI 513
              +   +       TLQ  G        L F   + +      F +T ++YG Y     
Sbjct: 135 LVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAYRVGP- 193

Query: 514 QHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-W 572
               S + Y+++LAY+ +  ACL  CF   L  M K      +    Y   ++  +F  W
Sbjct: 194 ---ESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSW 250

Query: 573 DFTVTHEKAVKLKQKNLSTEIRENLSELR--QENSKLTFNQLLTRFSAYMVAWVVSTGVA 630
           DF +  ++A  +K+  +S E +  L E R  Q   + T  Q   R  +Y+   V++  + 
Sbjct: 251 DFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLV 310

Query: 631 IACCAAVYYLAEYNLEFLKTHSNPGAVLLL----PFVVSCINLAVPCIYSMFRLVERYEM 686
           +   +A+++  +Y+ +    +      LLL    P V++ +N   P +++    +E Y  
Sbjct: 311 VGAISAIFWATKYSQD----NKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYP- 365

Query: 687 PRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE---------------CWETLIGQ 731
           P  EV + LI  + LK++ +G+       T+   G +               CWE  +G+
Sbjct: 366 PNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGE 425

Query: 732 DIYRLLLMDFVFSLVNSFLGEFLRRII----GMQLITSLGLQEFDIARNVLELIYAQTLV 787
           ++Y+L + +F+ ++  +FL    RR++      +    L  +EF + +NVL+++  QT+ 
Sbjct: 426 ELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVT 485

Query: 788 WIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLLFFPSFTG 847
           W+G+F+CPLLP +  + LF+ FY K  +L+ N +  S+ +RAS   TFF  L+       
Sbjct: 486 WMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASS-STFFFQLVLLLGLLL 544

Query: 848 VLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSW-IDTLSTRPGYLWVVWIYRNLIGSVH 906
               L   +  +  S DCG      LF +    W +       G   +     + +GS  
Sbjct: 545 AAVPLGYVVSSIHSSWDCG------LFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHA 598

Query: 907 FFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIKL 957
           F F L +++ ++  +    T+     I  L +Q++ + ++K  L+E L +L
Sbjct: 599 FSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRL 649


>gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens]
          Length = 706

 Score =  182 bits (461), Expect = 2e-45
 Identities = 158/601 (26%), Positives = 267/601 (44%), Gaps = 74/601 (12%)

Query: 411 SRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSF 470
           +R  RRSK    E L S+  W  TLK IGG+FG    SYF+ LR+LL  N+ + +L    
Sbjct: 119 ARLLRRSKEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACM 178

Query: 471 IIIP--------------------QFTVAKKNTLQFTGLEF--FTGVGYFRDTVMYYGFY 508
            ++P                     +    +  + F    F   +G GY   + ++YGFY
Sbjct: 179 TLLPTWLGGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFY 238

Query: 509 TNSTIQHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKL 568
                       +Y   L + F +G     C   +L       +   +         +  
Sbjct: 239 P----PRPRLAVTY---LCWAFAVGLI---CLLLILHRSVSGLKQTLLAESEALTSYSHR 288

Query: 569 IF-CWDFTVTHEKAVKLKQKNLSTEIRENLSE--LRQENSKLTFNQLLTRFSAYMVAWVV 625
           +F  WDF +  +  V+L+Q+ +  E++  L E  +R++ +  T  Q    +   ++  ++
Sbjct: 289 VFSAWDFGLCGDVHVRLRQRIILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLL 348

Query: 626 STGVAIACCAAVYYLAEYNLEFLKTHSNPGAVLL------LPFV-VSCINLAVPCIYSMF 678
              +  A    VY+     +E  +        LL      LP + ++ +N  +P ++ + 
Sbjct: 349 VVALLGAAFYGVYWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLI 408

Query: 679 RLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE--------------- 723
             +E Y   R  V++LL R +FL+++ + +L +   N +   G+                
Sbjct: 409 APLEGYTRSRQIVFILL-RTVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQL 467

Query: 724 -CWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRII-GM---QLITSLGLQEFDIARNVL 778
            CWET++GQ++Y+LLL D +  L  + L +F R+++ G+    L    G QEF +   VL
Sbjct: 468 PCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDEVL 527

Query: 779 ELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFF-I 837
            LIYAQT+VW+G FFCPLLP +  +   ++FY K ++L     P ++ +RAS    FF +
Sbjct: 528 GLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPL 587

Query: 838 FLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTL-STRPGYLWVVW 896
            LL   + + V   L  +I+ + PS  CGPFRG       I   I +L  T   +L+   
Sbjct: 588 VLLLGLAISSV--PLLYSIFLIPPSKLCGPFRGQSSIWAQIPESISSLPETTQNFLF--- 642

Query: 897 IYRNLIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIK 956
                +G+  F   L LI  I+      +      +I  L  Q   E ++K+FL  + + 
Sbjct: 643 ----FLGTQAFAVPLLLISSILMAYTVALANSYGRLISELKRQRQTEAQNKVFLARRAVA 698

Query: 957 L 957
           L
Sbjct: 699 L 699


>gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens]
          Length = 712

 Score =  182 bits (461), Expect = 2e-45
 Identities = 158/601 (26%), Positives = 267/601 (44%), Gaps = 74/601 (12%)

Query: 411 SRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSF 470
           +R  RRSK    E L S+  W  TLK IGG+FG    SYF+ LR+LL  N+ + +L    
Sbjct: 125 ARLLRRSKEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACM 184

Query: 471 IIIP--------------------QFTVAKKNTLQFTGLEF--FTGVGYFRDTVMYYGFY 508
            ++P                     +    +  + F    F   +G GY   + ++YGFY
Sbjct: 185 TLLPTWLGGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFY 244

Query: 509 TNSTIQHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKL 568
                       +Y   L + F +G     C   +L       +   +         +  
Sbjct: 245 P----PRPRLAVTY---LCWAFAVGLI---CLLLILHRSVSGLKQTLLAESEALTSYSHR 294

Query: 569 IF-CWDFTVTHEKAVKLKQKNLSTEIRENLSE--LRQENSKLTFNQLLTRFSAYMVAWVV 625
           +F  WDF +  +  V+L+Q+ +  E++  L E  +R++ +  T  Q    +   ++  ++
Sbjct: 295 VFSAWDFGLCGDVHVRLRQRIILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLL 354

Query: 626 STGVAIACCAAVYYLAEYNLEFLKTHSNPGAVLL------LPFV-VSCINLAVPCIYSMF 678
              +  A    VY+     +E  +        LL      LP + ++ +N  +P ++ + 
Sbjct: 355 VVALLGAAFYGVYWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLI 414

Query: 679 RLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE--------------- 723
             +E Y   R  V++LL R +FL+++ + +L +   N +   G+                
Sbjct: 415 APLEGYTRSRQIVFILL-RTVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQL 473

Query: 724 -CWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRII-GM---QLITSLGLQEFDIARNVL 778
            CWET++GQ++Y+LLL D +  L  + L +F R+++ G+    L    G QEF +   VL
Sbjct: 474 PCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDEVL 533

Query: 779 ELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFF-I 837
            LIYAQT+VW+G FFCPLLP +  +   ++FY K ++L     P ++ +RAS    FF +
Sbjct: 534 GLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPL 593

Query: 838 FLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTL-STRPGYLWVVW 896
            LL   + + V   L  +I+ + PS  CGPFRG       I   I +L  T   +L+   
Sbjct: 594 VLLLGLAISSV--PLLYSIFLIPPSKLCGPFRGQSSIWAQIPESISSLPETTQNFLF--- 648

Query: 897 IYRNLIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIK 956
                +G+  F   L LI  I+      +      +I  L  Q   E ++K+FL  + + 
Sbjct: 649 ----FLGTQAFAVPLLLISSILMAYTVALANSYGRLISELKRQRQTEAQNKVFLARRAVA 704

Query: 957 L 957
           L
Sbjct: 705 L 705


>gi|21071070 transmembrane channel-like 1 [Homo sapiens]
          Length = 760

 Score =  138 bits (347), Expect = 3e-32
 Identities = 130/563 (23%), Positives = 242/563 (42%), Gaps = 88/563 (15%)

Query: 431 WQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIPQFT------------- 477
           W+  +K I  +FG+SV SYF FLRW+   N+  FIL FS I++P++              
Sbjct: 170 WENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTV 229

Query: 478 --VAKKNTLQFTGLEFFTGVGYFRDTVMYYGFYTNS-TIQHGNSGASYNMQLAYIFTIGA 534
               + +   F  L  F G+  +  +V++YG+Y N  TI   N    + + L+Y      
Sbjct: 230 PRAEEASAANFGVLYDFNGLAQY--SVLFYGYYDNKRTIGWMN----FRLPLSYFLVGIM 283

Query: 535 CLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFCWDFTVTHEKAVKLKQKNLSTEIR 594
           C+   F  +L +M K   ++            K+   WD+ + + +    K  +++   +
Sbjct: 284 CIGYSFLVVLKAMTKNIGDDGGGDDNTFNFSWKVFTSWDYLIGNPETADNKFNSITMNFK 343

Query: 595 ENLSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYNLEFLKTHSNP 654
           E ++E  ++ +++  N  L RF  ++  + V   +       +++  + + EF +   +P
Sbjct: 344 EAITE--EKAAQVEENVHLIRFLRFLANFFVFLTLG-GSGYLIFWAVKRSQEFAQ--QDP 398

Query: 655 GAVLL-----LPFVVSCINLAVPCIYSMFRLVERY------EMPRHEVYVLLIRNIFLKI 703
             +       +  V+S + +  P ++ +F  +E Y      +     ++ LL+ N+++ I
Sbjct: 399 DTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFI 458

Query: 704 SIIG------------------------ILCY------------YWLNTVALSGEECWET 727
             +                         I  Y            ++++   +    CWET
Sbjct: 459 LALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVPRGPCWET 518

Query: 728 LIGQDIYRLLLMDFVFSLVNSFLGEFLR----RIIGMQLITSL-----GLQEFDIARNVL 778
           ++GQ+  RL + D + + V   +G+FLR    R         L        EFDI+ NVL
Sbjct: 519 MVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVL 578

Query: 779 ELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIF 838
            LI+ Q ++W+G FF P LP I ++ L    Y +  ++M    P ++ ++AS+   F++ 
Sbjct: 579 ALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLG 638

Query: 839 LLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPGYLWVVWIY 898
           +L    F   +  L + +  L PS DCGPF G     + ++  I          W+  I 
Sbjct: 639 MLLLILFLSTMPVLYMIV-SLPPSFDCGPFSGK----NRMFEVIGETLEHDFPSWMAKIL 693

Query: 899 RNLIGSVHFFFILTLIVLIITYL 921
           R L        ++ ++VL I YL
Sbjct: 694 RQLSNPGLVIAVILVMVLAIYYL 716


>gi|94536852 transmembrane cochlear-expressed protein 2 [Homo
           sapiens]
          Length = 906

 Score =  134 bits (337), Expect = 4e-31
 Identities = 137/588 (23%), Positives = 245/588 (41%), Gaps = 109/588 (18%)

Query: 366 IKAIRNQPRTMEEK----RNLRKIVDKE-------KSKQTHRILQLNCCIQCLNSISRAY 414
           I  +R++P  M +K    R  ++ V+K        K KQ +    L         +++ +
Sbjct: 167 IATMRSKPWPMAKKLTELREAQEFVEKYEGALGKGKGKQLYAYKML---------MAKKW 217

Query: 415 RRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIP 474
            + K            W+  +K I   FG+SV SYF FLRW+   N+  F L F  +IIP
Sbjct: 218 VKFKRDFDNFKTQCIPWEMKIKDIESHFGSSVASYFIFLRWMYGVNLVLFGLIFGLVIIP 277

Query: 475 QFTVA---------------KKNTLQFTGLEFFTGVGYFRDTVMYYGFYTNSTIQHGNSG 519
           +  +                ++  + F+ L  F G  Y + + ++YG+Y N   Q     
Sbjct: 278 EVLMGMPYGSIPRKTVPRAEEEKAMDFSVLWDFEG--YIKYSALFYGYYNN---QRTIGW 332

Query: 520 ASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGIT---KLIFCWDFTV 576
             Y + +AY     +        ++ SMA   + +       S   T   K+   WD+ +
Sbjct: 333 LRYRLPMAYFMVGVSVFGYSLIIVIRSMASNTQGSTGEGE--SDNFTFSFKMFTSWDYLI 390

Query: 577 THEKAVKLKQKNLSTEIRENLSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAA 636
            + +    K  +++T  +E++ + ++ N +   +  LTRF   +  ++      I CC  
Sbjct: 391 GNSETADNKYASITTSFKESIVDEQESNKEENIH--LTRFLRVLANFL------IICCLC 442

Query: 637 -----VYYLAEYNLEFLKTHSNPGAVLL-LPFVVSCINLAVPCIYSMFRLVERYEMPRH- 689
                +Y++ + + +F K  +        +  V+S + +  P ++     +E Y  PR  
Sbjct: 443 GSGYLIYFVVKRSQQFSKMQNVSWYERNEVEIVMSLLGMFCPPLFETIAALENYH-PRTG 501

Query: 690 ------EVYVLLIRNIFL--------------------KISIIGILCYY----W------ 713
                  ++ L + N++                      I+   +  YY    W      
Sbjct: 502 LKWQLGRIFALFLGNLYTFLLALMDDVHLKLANEETIKNITHWTLFNYYNSSGWNESVPR 561

Query: 714 --LNTVALSGEECWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRR--IIGMQLITSLGLQ 769
             L+   +    CWET +G +  RL + D + + +   LG+FLR   +  M       L+
Sbjct: 562 PPLHPADVPRGSCWETAVGIEFMRLTVSDMLVTYITILLGDFLRACFVRFMNYCWCWDLE 621

Query: 770 -------EFDIARNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQP 822
                  EFDI+ NVL LI+ Q ++W+G F+ P L  I ++ L    Y +  ++M +  P
Sbjct: 622 AGFPSYAEFDISGNVLGLIFNQGMIWMGSFYAPGLVGINVLRLLTSMYFQCWAVMSSNVP 681

Query: 823 PSKAWRASQMMTFFIFLLFFPSFTGVLCTLAITIWRLKPSADCGPFRG 870
             + ++AS+   F++ LL    F  +L  +A TI  L PS DCGPF G
Sbjct: 682 HERVFKASRSNNFYMGLLLLVLFLSLL-PVAYTIMSLPPSFDCGPFSG 728


>gi|122937502 transmembrane channel-like 3 [Homo sapiens]
          Length = 1100

 Score =  103 bits (258), Expect = 6e-22
 Identities = 75/261 (28%), Positives = 127/261 (48%), Gaps = 23/261 (8%)

Query: 722 EECWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRIIGMQL-----------ITSLGLQE 770
           ++CWET +GQ++ +L ++D +F++ +  L +F R +    L               G  E
Sbjct: 497 DQCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFPEYG--E 554

Query: 771 FDIARNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRAS 830
           F IA NVL L+Y Q ++W+G FF P LP   ++ L  + Y ++ +++    P  + +RAS
Sbjct: 555 FKIAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRAS 614

Query: 831 QMMTFFIFLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPG 890
           +   F++ +L F  F  +L T+   I R KPS +CGPF G       IY  +     +  
Sbjct: 615 RSNNFYLAMLLFMLFLCMLPTI-FAIVRYKPSLNCGPFSGQ----EKIYDIVSETIEKDF 669

Query: 891 YLWVVWIYRNLIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIIN---EGKDK 947
            +W   +  ++   V     + L+ ++I YL   I    K+    L  QI N   E K K
Sbjct: 670 PVWFGSVVGHISSPVVILPAVLLLFMLIYYLQ-SIARSLKLSNHQLKMQIQNARSEDKKK 728

Query: 948 MF-LIEKLIKLQDMEKKANPS 967
           +  ++E  I+ Q+   K  P+
Sbjct: 729 VAQMVEARIQTQEESTKKLPN 749



 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 78/310 (25%), Positives = 128/310 (41%), Gaps = 24/310 (7%)

Query: 431 WQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIPQF------------TV 478
           W+  +K I   FG+ V SYF FLRWL   NI   I+  +FI+IP+             T+
Sbjct: 123 WEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPFGSTARKTI 182

Query: 479 AKKNTLQFTGLEFFTGV-GYFRDTVMYYGFYTNSTIQHGNSGASYNMQLAYIFTIGACLT 537
            K+       L+    + GY + +V++YG+Y     +     A Y + LAY     A   
Sbjct: 183 PKEQVSSAQDLDTVWSLGGYLQYSVLFYGYYGR---ERKIGRAGYRLPLAYFLVGMAVFA 239

Query: 538 TCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-WDFTVTHEKAVKLKQKNLSTEIREN 596
             F  LL  MAK  R +  +    +      +FC WD+ + + +A + K   +   IRE 
Sbjct: 240 YSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEAAESKTAAIVNSIREA 299

Query: 597 LSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAE--YNLEFLKTHSNP 654
           + E   E  K     L       ++A ++           +Y++ +    LE  K     
Sbjct: 300 ILE---EQEKKKSKNLAVTICLRIIANILVLLSLAGSIYLIYFVVDRSQKLEQSKKELTL 356

Query: 655 GAVLLLPFVVSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWL 714
                +  VVS + +  P  + +   +E Y  PR  +   L R + L +  +  L    L
Sbjct: 357 WEKNEVSVVVSLVTMIAPSAFDLIAALEMYH-PRTTLRFQLARVLVLYLGNLYSLIIALL 415

Query: 715 NTV-ALSGEE 723
           + V ++S EE
Sbjct: 416 DKVNSMSIEE 425


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 46/196 (23%), Positives = 61/196 (31%), Gaps = 31/196 (15%)

Query: 34   GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSA 93
            G P +PGP   P  PG R        R  P  PG +  P +P ++ +P   G +      
Sbjct: 1018 GSPGLPGP---PGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLT 1074

Query: 94   ASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHP 153
                    P                      QP YPG+   P   G      Y GS    
Sbjct: 1075 GLTGDKGEP------------------GPPGQPGYPGATGPPGLPGIKGERGYTGSAGEK 1116

Query: 154  DHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYPGADIQ 213
                  EP  PG++     PGP       G + N      +        G+P +PG    
Sbjct: 1117 G-----EPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQ-----GFQGQPGFPGPPGP 1166

Query: 214  PNSPPFFGEPDYPSAE 229
            P  P   G P  P  +
Sbjct: 1167 PGFPGKVGSPGPPGPQ 1182



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 63/241 (26%), Positives = 78/241 (32%), Gaps = 28/241 (11%)

Query: 14   PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTR---------PD 64
            P  P   G Q   +G    +G P  PGP+  P +PG   +P     +             
Sbjct: 1023 PGPPGLPG-QRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKG 1081

Query: 65   YPGSLAEPNYPRSLSN---PDYSGTRSNAYSAASRTSPDHPTS--LPEPDYSEFQSHPYH 119
             PG   +P YP +      P   G R    SA  +  P  P S  LP P        P  
Sbjct: 1082 EPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGP------PGPAG 1135

Query: 120  RASSRQPD-YPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRAN 178
                R P    G + +  F G        G    P   GS  P  PG Q+     G R  
Sbjct: 1136 PRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGS--PGPPGPQAEKGSEGIRGP 1193

Query: 179  LNHPGSRKNLEHTSFRINPYADSL-GKPDYPG--ADIQPNSPP-FFGEPDYPSAEDNQNL 234
               PGS         +     D L GK   PG   D  P  PP   G P +     +  L
Sbjct: 1194 SGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGL 1253

Query: 235  P 235
            P
Sbjct: 1254 P 1254



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 51/215 (23%), Positives = 73/215 (33%), Gaps = 31/215 (14%)

Query: 19   YSGS--QNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRT---RPDYPGSLAEPN 73
            Y+GS  +    G   ++G P  PGP       G + N      +    +P +PG    P 
Sbjct: 1109 YTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPG 1168

Query: 74   YPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQR 133
            +P  + +P   G ++   S   R     P+ LP               S   P  PG Q 
Sbjct: 1169 FPGKVGSPGPPGPQAEKGSEGIRG----PSGLP--------------GSPGPPGPPGIQG 1210

Query: 134  NPDFAGSSSSGNYAGSRTHPDHFGSL----EPDYPGAQSNSDHPGPRANLNHPGSRKNLE 189
                 G        G R  P   G       P + G   +   PGP+ +   PG   +  
Sbjct: 1211 PAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTG 1270

Query: 190  HTSFRINPYA-DSLGKPDYPGADIQPNSPPFFGEP 223
                   P A    G+P  PG  + P  PP  G+P
Sbjct: 1271 RPGAEGEPGAMGPQGRPGPPG-HVGPPGPP--GQP 1302



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 60/248 (24%), Positives = 78/248 (31%), Gaps = 53/248 (21%)

Query: 39   PGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYS-----------GTR 87
            PGP  +   PG    P ++  + RP  PG +  P  P        S           G R
Sbjct: 1263 PGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGER 1322

Query: 88   SNAYSAASRTSPDHPTSLPEP--DYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGN 145
              A        P HP    EP  D +  +  P  +     P  PG + +P  AG      
Sbjct: 1323 GLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGP--PGPKGDPGAAGQKGQAG 1380

Query: 146  Y---AGSRTHPDHFGSLEPDYP----GAQSNSDHPGPRANLNHPG--------------- 183
                AG    P   GS+ P  P    G + +   PGP  +   PG               
Sbjct: 1381 EKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIK 1440

Query: 184  -----------SRKNLEHTSFRINPY--ADSLGKPDYPGADIQPNSPPFFGEPDYP---S 227
                         +   +TS    P   A + G+P  PG D  P  P   G P  P    
Sbjct: 1441 RFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIG 1500

Query: 228  AEDNQNLP 235
             E  Q LP
Sbjct: 1501 REGRQGLP 1508



 Score = 31.2 bits (69), Expect = 5.1
 Identities = 43/185 (23%), Positives = 55/185 (29%), Gaps = 35/185 (18%)

Query: 14   PDYPDYSGS--------QNRTQGYLKTQGYPDVPGPLNNPDY---------------PGT 50
            P +P   GS        +  ++G     G P  PGP   P                 PG 
Sbjct: 1167 PGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGL 1226

Query: 51   RSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDY 110
            R +P           PG +  P +     +P   G + +        S   P +  EP  
Sbjct: 1227 RGDPGPAGP------PGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGA 1280

Query: 111  SEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNS 170
               Q  P        P  PG    P  AG S+ G   G R      G      PG     
Sbjct: 1281 MGPQGRPGPPGHVGPPGPPG---QPGPAGISAVG-LKGDRGATGERGL--AGLPGQPGPP 1334

Query: 171  DHPGP 175
             HPGP
Sbjct: 1335 GHPGP 1339


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 88/377 (23%), Positives = 116/377 (30%), Gaps = 50/377 (13%)

Query: 13   DPDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEP 72
            +P  P   G+   +QG    QG    PG    P  PG    P S      P + G   E 
Sbjct: 636  EPGPPGQQGNHG-SQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEK 694

Query: 73   NY---PRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYP 129
                 P S   P Y G R    ++ +R          E  +  F+     +    +P  P
Sbjct: 695  GAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAP 754

Query: 130  GSQRNPDFAGSSSSGNYAGSRTHPDHFGSL-EPDYPGAQSNSDHPGPRANLNHPG----- 183
            G +      G       AG    P   G   +   PG       PGP+ ++  PG     
Sbjct: 755  GPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPI 814

Query: 184  -----SRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLPSTW 238
                 S K  +           S G+   PGA  QP      G+   P     + LP   
Sbjct: 815  GEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQ 874

Query: 239  REPDY-----------SDAENGH-------DYGSSETPKMTRGVL---SRTSSIQPSFRH 277
              P +            D   GH        +     P    GVL    +T  + P    
Sbjct: 875  GPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGER 934

Query: 278  RSDDPVGSLWGENDYP--EGIEMASMEMANSYGHSLPGAPGS-GYVNPAYV-GESGPVHA 333
                P G   GE   P  EG E A  E+         G PG  G   PA + G  GP   
Sbjct: 935  GPPGPPGPP-GEQGLPGLEGREGAKGEL---------GPPGPLGKEGPAGLRGFPGPKGG 984

Query: 334  YGNPPLSECDWHKSPQG 350
             G+P  +     K P G
Sbjct: 985  PGDPGPTGLKGDKGPPG 1001


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 57/233 (24%), Positives = 79/233 (33%), Gaps = 17/233 (7%)

Query: 14   PDYPDYSGSQN--RTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPG---- 67
            P  P  +G+     T+G +   G P  PGPL  P   G          + +P  PG    
Sbjct: 880  PGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939

Query: 68   --SLAEPNYPRSLS--NPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASS 123
              S  EP  P      +P+  G++           P  P       Y      P     S
Sbjct: 940  KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL---PGIPGVSGPKGYQGLPGDPGQPGLS 996

Query: 124  RQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSL-EPDYPGAQSNSDHPGPRANLNHP 182
             QP  PG    P   G+       G    P   G++ +  +PG Q     PGP      P
Sbjct: 997  GQPGLPGP---PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQP 1053

Query: 183  GSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLP 235
            GS         + +P   S+G P  PG   +P  P + G P    +  +  LP
Sbjct: 1054 GSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLP 1106



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 51/205 (24%), Positives = 59/205 (28%), Gaps = 9/205 (4%)

Query: 34   GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSA 93
            G P +PGP   P  PG   NP    S   P  PG    P        P + GT       
Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133

Query: 94   ASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHP 153
                 P +P    EP       HP       QP  PG +  P   G        G    P
Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHP------GQPGPPGEKGKPGQDGIPGPAGQKGEPGQP 1187

Query: 154  DHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADS-LGKPDYPGADI 212
                   P  PG        G      +PG         F   P      G P  PG  +
Sbjct: 1188 GFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPAL 1247

Query: 213  Q--PNSPPFFGEPDYPSAEDNQNLP 235
            +    +P   G P  P     Q LP
Sbjct: 1248 EGPKGNPGPQGPPGRPGPTGFQGLP 1272



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 51/215 (23%), Positives = 71/215 (33%), Gaps = 20/215 (9%)

Query: 17  PDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPR 76
           P  +G++   +G+  + G+P + GP   P  PG +  P S+   + P   G+   P  P 
Sbjct: 122 PGCNGTKGE-RGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG 180

Query: 77  SLSNPDYSGTRS--NAYSAASRTSPDHPTSLPEPDYS---EFQSHPYHRASSRQPDYPGS 131
               P  +G               P  P  LP P  +    FQ     +         G 
Sbjct: 181 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQ------GL 234

Query: 132 QRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHT 191
           Q  P   G  S       R     F   +   PG +     PG R     PG  K  +  
Sbjct: 235 QGPPGPPGQISE----QKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGE 290

Query: 192 SFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYP 226
                      GKP   G + QP  P   G+P YP
Sbjct: 291 QGE----PGKRGKPGKDGENGQPGIPGLPGDPGYP 321



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 55/236 (23%), Positives = 72/236 (30%), Gaps = 27/236 (11%)

Query: 13   DPDYPDYSGSQNRTQGYLKTQGYPDVPGP------LNNPDYPGTRSNPYSVASRTRPDYP 66
            DP  P   G+    +G     G+P  PGP         P  PG    P  V     P  P
Sbjct: 1102 DPGLPGLPGTPG-AKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQP 1160

Query: 67   GSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQP 126
            G   E   P     P  +G +           P  P     P           +     P
Sbjct: 1161 GPPGEKGKPGQDGIPGPAGQKG---------EPGQP-GFGNPGPPGLPGLSGQKGDGGLP 1210

Query: 127  DYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRK 186
              PG+   P   G      + G +  P   GS  P   G + N   PGP+     PG   
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGN---PGPQGPPGRPGP-- 1265

Query: 187  NLEHTSFRINPYADS-LGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLPSTWREP 241
                T F+  P  +   G P   G   +  +P   G P  P  + +Q  P     P
Sbjct: 1266 ----TGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP 1317



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 51/221 (23%), Positives = 65/221 (29%), Gaps = 33/221 (14%)

Query: 38  VPGPLNNPDYPGTRS-----NPYSVASRTRPDYPGSLAEPNYPRSLSNP------DYSGT 86
           +PGP  NP YPG         P  +     P  P  L  P  P  L  P      ++ G 
Sbjct: 166 LPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGP 225

Query: 87  RSNAYSAASRTSPDHPTSLPE---PDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSS 143
           +        +  P  P  + E   P   EFQ         R P  P   R P        
Sbjct: 226 KGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEK 285

Query: 144 GNYA-----GSRTHPDHFGSL----------EPDYPGAQSNSDHPGPRANLNHPGSRKNL 188
           G        G R  P   G            +P YPG        G + +   PG    +
Sbjct: 286 GEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLV 345

Query: 189 ---EHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYP 226
                T   I     ++G P  PG   +   P   G P  P
Sbjct: 346 IPRPGTGITIGE-KGNIGLPGLPGEKGERGFPGIQGPPGLP 385



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 49/206 (23%), Positives = 63/206 (30%), Gaps = 13/206 (6%)

Query: 34   GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSA 93
            G+P  PGP      PG    P     +  P  PG    P  P     P  SG + +    
Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG-FGNPGPP---GLPGLSGQKGDGGLP 1210

Query: 94   ASRTSPDHPTSLPEPDYSEFQS--HPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRT 151
                +P  P    EP +  F     P     S  P   G + NP   G        G + 
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQG 1270

Query: 152  HPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYPGAD 211
             P   G      PG   N    G + N   PG    L        P     G P  PG +
Sbjct: 1271 LPGPEGP-----PGLPGNGGIKGEKGNPGQPGL-PGLPGLKGDQGP-PGLQGNPGRPGLN 1323

Query: 212  IQPNSPPFFGEPDYPSAEDNQNLPST 237
                 P   G P +P  +    +P +
Sbjct: 1324 GMKGDPGLPGVPGFPGMKGPSGVPGS 1349



 Score = 37.4 bits (85), Expect = 0.071
 Identities = 66/311 (21%), Positives = 92/311 (29%), Gaps = 37/311 (11%)

Query: 34  GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNP----DYSGTRSN 89
           G P  PG L  P   G +    +   +  P  PG+   P +P S   P     + G + +
Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559

Query: 90  AYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNP---DFAGSSSSGNY 146
                S  +P  P              P        P  PG +  P    F G       
Sbjct: 560 KGELGSPGAPGLP------------GLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGN 607

Query: 147 AGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPD 206
            G    P + G + P   G        G +    +PG +  +              GKP 
Sbjct: 608 PGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPG-QPGIPGPKGDPGQTITQPGKPG 666

Query: 207 YPGADIQPNSPPFFGEPDYPSAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGVLS 266
            PG   +       G+P  P       +P +  EP       G        PK   G+  
Sbjct: 667 LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIP----GIGLPGPPGPKGFPGIPG 722

Query: 267 RTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLPGAPGSGYVNPAYVG 326
              +     R   + P G        P G      E     G +LPG PG   + P + G
Sbjct: 723 PPGAPGTPGRIGLEGPPG--------PPGFPGPKGEP----GFALPGPPGPPGL-PGFKG 769

Query: 327 ESGPVHAYGNP 337
             GP    G P
Sbjct: 770 ALGPKGDRGFP 780



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 77/336 (22%), Positives = 103/336 (30%), Gaps = 64/336 (19%)

Query: 33  QGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAE--PNYPRSLSNPDYSGTRSNA 90
           +G+P + GP   P  PG       +     P +PG   +     P  +S P   G     
Sbjct: 373 RGFPGIQGPPGLPGPPGAA----VMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQP 428

Query: 91  YSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSR 150
             A     P  P     P   E            +P  PG   +P   G        G +
Sbjct: 429 -GAPGLPGPPGPAGPHIPPSDEI----------CEPGPPGPPGSPGDKGLQGEQGVKGDK 477

Query: 151 --THPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYP 208
             T  +  G+     PG       PGP  +L  PG +K  +  +    P     G P  P
Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG-QKGEKGQAGATGP----KGLPGIP 532

Query: 209 GADIQPNSPPFFGEP----DYPSAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGV 264
           GA   P  P   GEP     +P  + ++                  + GS   P +    
Sbjct: 533 GAPGAPGFPGSKGEPGDILTFPGMKGDKG-----------------ELGSPGAPGLPG-- 573

Query: 265 LSRTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLPGAPGS------- 317
           L  T            D +  L G    P GI     E        LPG PG+       
Sbjct: 574 LPGTP---------GQDGLPGLPGPKGEPGGITFKG-ERGPPGNPGLPGLPGNIGPMGPP 623

Query: 318 GYVNPAYVGESGPVHAYGNPPLSECDWHKSPQGQKL 353
           G+  P  VGE G     GNP        K   GQ +
Sbjct: 624 GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTI 659



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 46/208 (22%), Positives = 65/208 (31%), Gaps = 37/208 (17%)

Query: 27  QGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGT 86
           +G+   +G+P +PG      +PG    P     +     PG    P  P+ +  P   G 
Sbjct: 50  RGFPGLEGHPGLPG------FPGPEGPPGPRGQKGDDGIPG----PPGPKGIRGP--PGL 97

Query: 87  RSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNY 146
                +      P H    P P     Q  P    +  +  +PGS   P   G       
Sbjct: 98  PGFPGTPGLPGMPGH-DGAPGP-----QGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGI 151

Query: 147 AGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPD 206
            G +  P     +    PG + N  +PGP      PG                  +G P 
Sbjct: 152 PGMKGEPGSI--IMSSLPGPKGNPGYPGPPGIQGLPGP-----------TGIPGPIGPPG 198

Query: 207 YPGADIQPNSPPFFGEPDYPSAEDNQNL 234
            PG       PP  G P  P  + N  L
Sbjct: 199 PPGL----MGPP--GPPGLPGPKGNMGL 220



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 50/214 (23%), Positives = 61/214 (28%), Gaps = 45/214 (21%)

Query: 27  QGYLKTQGYPDVPGP-------LNNPDYPGTRSNPYS------------VASRTRPDYPG 67
           QG     G P +PGP       +  P  PG   NP                    P  PG
Sbjct: 637 QGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPG 696

Query: 68  SLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHP--TSLPEPDYSEFQSHPYHRASSRQ 125
           S  EP  P  +  P   G +          +P  P    L  P        P        
Sbjct: 697 SKGEPGIP-GIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755

Query: 126 PDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSR 185
           P  PG    P F G+       G R  P       P  PG       PGP+ ++   G  
Sbjct: 756 PGPPGPPGLPGFKGALGP---KGDRGFPG-----PPGPPGRTGLDGLPGPKGDVGPNGQ- 806

Query: 186 KNLEHTSFRINPYADSLGKPDYPGADIQ-PNSPP 218
                           +G P  PG  +Q P  PP
Sbjct: 807 -------------PGPMGPPGLPGIGVQGPPGPP 827



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 57/257 (22%), Positives = 69/257 (26%), Gaps = 37/257 (14%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPN 73
           P+ P     Q    G     G   + GP   P +PGT            P  PG      
Sbjct: 67  PEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGT------------PGLPGMPGHDG 114

Query: 74  YPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQR 133
            P     P  +GT+       S   P        P     +  P    S      PG + 
Sbjct: 115 APGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEP---GSIIMSSLPGPKG 171

Query: 134 NPDFAGSSSSGNYAGSRTHPDHFGSL-EPDYPGAQSNSDHPGPRAN--LNHPGSRKNLEH 190
           NP + G        G    P   G    P   G       PGP+ N  LN  G +     
Sbjct: 172 NPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGE 231

Query: 191 TSFRINP--------------YADSLGKPDYPGADIQPNSPPFFGEPDYPSAE----DNQ 232
              +  P                   G    PG    P  P   G P  P  E      Q
Sbjct: 232 QGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQ 291

Query: 233 NLPSTWREPDYSDAENG 249
             P    +P   D ENG
Sbjct: 292 GEPGKRGKPG-KDGENG 307



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 38/171 (22%), Positives = 50/171 (29%), Gaps = 25/171 (14%)

Query: 33  QGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNY--PRSLSNPDYSGTRSNA 90
           +G+P +PGP   P  PGT            P +PG   EP +  P     P   G +   
Sbjct: 715 KGFPGIPGP---PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL 771

Query: 91  YSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSG------ 144
                R  P  P     P  +     P  +        PG    P   G    G      
Sbjct: 772 GPKGDRGFPGPPGP---PGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828

Query: 145 -----------NYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGS 184
                         G +  P   G   P  PG + +   PG    +  PGS
Sbjct: 829 IPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGS 879


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 57/233 (24%), Positives = 79/233 (33%), Gaps = 17/233 (7%)

Query: 14   PDYPDYSGSQN--RTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPG---- 67
            P  P  +G+     T+G +   G P  PGPL  P   G          + +P  PG    
Sbjct: 880  PGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939

Query: 68   --SLAEPNYPRSLS--NPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASS 123
              S  EP  P      +P+  G++           P  P       Y      P     S
Sbjct: 940  KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL---PGIPGVSGPKGYQGLPGDPGQPGLS 996

Query: 124  RQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSL-EPDYPGAQSNSDHPGPRANLNHP 182
             QP  PG    P   G+       G    P   G++ +  +PG Q     PGP      P
Sbjct: 997  GQPGLPGP---PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQP 1053

Query: 183  GSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLP 235
            GS         + +P   S+G P  PG   +P  P + G P    +  +  LP
Sbjct: 1054 GSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLP 1106



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 53/210 (25%), Positives = 60/210 (28%), Gaps = 16/210 (7%)

Query: 34   GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSA 93
            G P +PGP   P  PG   NP    S   P  PG    P        P + GT       
Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133

Query: 94   ASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHP 153
                 P +P    EP       HP       QP  PG +  P   G        G    P
Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHP------GQPGPPGEKGKPGQDGIPGPAGQKGEPGQP 1187

Query: 154  DHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADS-LGKPDYPGADI 212
                   P  PG        G      +PG         F   P      G P  PG  +
Sbjct: 1188 GFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPAL 1247

Query: 213  Q-------PNSPPFFGEPDYPSAEDNQNLP 235
            +       P  PP  G P  P  E    LP
Sbjct: 1248 EGPKGNPGPQGPP--GRPGLPGPEGPPGLP 1275



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 51/215 (23%), Positives = 71/215 (33%), Gaps = 20/215 (9%)

Query: 17  PDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPR 76
           P  +G++   +G+  + G+P + GP   P  PG +  P S+   + P   G+   P  P 
Sbjct: 122 PGCNGTKGE-RGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG 180

Query: 77  SLSNPDYSGTRS--NAYSAASRTSPDHPTSLPEPDYS---EFQSHPYHRASSRQPDYPGS 131
               P  +G               P  P  LP P  +    FQ     +         G 
Sbjct: 181 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQ------GL 234

Query: 132 QRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHT 191
           Q  P   G  S       R     F   +   PG +     PG R     PG  K  +  
Sbjct: 235 QGPPGPPGQISE----QKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGE 290

Query: 192 SFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYP 226
                      GKP   G + QP  P   G+P YP
Sbjct: 291 QGE----PGKRGKPGKDGENGQPGIPGLPGDPGYP 321



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 51/221 (23%), Positives = 65/221 (29%), Gaps = 33/221 (14%)

Query: 38  VPGPLNNPDYPGTRS-----NPYSVASRTRPDYPGSLAEPNYPRSLSNP------DYSGT 86
           +PGP  NP YPG         P  +     P  P  L  P  P  L  P      ++ G 
Sbjct: 166 LPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGP 225

Query: 87  RSNAYSAASRTSPDHPTSLPE---PDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSS 143
           +        +  P  P  + E   P   EFQ         R P  P   R P        
Sbjct: 226 KGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEK 285

Query: 144 GNYA-----GSRTHPDHFGSL----------EPDYPGAQSNSDHPGPRANLNHPGSRKNL 188
           G        G R  P   G            +P YPG        G + +   PG    +
Sbjct: 286 GEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLV 345

Query: 189 ---EHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYP 226
                T   I     ++G P  PG   +   P   G P  P
Sbjct: 346 IPRPGTGITIGE-KGNIGLPGLPGEKGERGFPGIQGPPGLP 385



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 49/204 (24%), Positives = 63/204 (30%), Gaps = 15/204 (7%)

Query: 34   GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSA 93
            G+P  PGP      PG    P     +  P  PG    P  P     P  SG + +    
Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG-FGNPGPP---GLPGLSGQKGDGGLP 1210

Query: 94   ASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHP 153
                +P  P    EP +  F   P  +     P  PG    P   G   +    G    P
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGF---PGVQGPPGPPGSPG----PALEGPKGNPGPQGPPGRP 1263

Query: 154  DHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYPGADIQ 213
               G   P  PG   N    G + N   PG    L        P     G P  PG +  
Sbjct: 1264 GLPGPEGP--PGLPGNGGIKGEKGNPGQPGL-PGLPGLKGDQGP-PGLQGNPGRPGLNGM 1319

Query: 214  PNSPPFFGEPDYPSAEDNQNLPST 237
               P   G P +P  +    +P +
Sbjct: 1320 KGDPGLPGVPGFPGMKGPSGVPGS 1343



 Score = 38.5 bits (88), Expect = 0.032
 Identities = 49/202 (24%), Positives = 64/202 (31%), Gaps = 25/202 (12%)

Query: 33   QGYPDVPGPLNN---------PDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLS---- 79
            +G P +PG   N         P  PG    P +      P +PG+   P  P+ +S    
Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG-PKGISGPPG 1140

Query: 80   NPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDY--PGSQRNPDF 137
            NP   G             P  P    +P           +    QP +  PG    P  
Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200

Query: 138  AGSSSSGNYAGSRTHPDHFGSL-EPDYPGAQSNSDHPGPRANLNHPGS-RKNLEHTSFRI 195
            +G    G   G   +P   G   EP + G       PGP      PGS    LE      
Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP------PGSPGPALEGPKGNP 1254

Query: 196  NPYADSLGKPDYPGADIQPNSP 217
             P     G+P  PG +  P  P
Sbjct: 1255 GPQGPP-GRPGLPGPEGPPGLP 1275



 Score = 38.1 bits (87), Expect = 0.042
 Identities = 52/229 (22%), Positives = 66/229 (28%), Gaps = 22/229 (9%)

Query: 13   DPDYPDYSGSQNRTQGYLKTQGYPDVPGP------LNNPDYPGTRSNPYSVASRTRPDYP 66
            DP  P   G+    +G     G+P  PGP         P  PG    P  V     P  P
Sbjct: 1102 DPGLPGLPGTPG-AKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQP 1160

Query: 67   GSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQP 126
            G   E   P     P  +G +           P  P     P           +     P
Sbjct: 1161 GPPGEKGKPGQDGIPGPAGQKG---------EPGQP-GFGNPGPPGLPGLSGQKGDGGLP 1210

Query: 127  DYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRK 186
              PG+   P   G      + G +  P   GS  P   G + N   PGP+     PG   
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGN---PGPQGPPGRPGLPG 1267

Query: 187  NLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLP 235
                     N      G+   PG    P  P   G+   P  + N   P
Sbjct: 1268 PEGPPGLPGN--GGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP 1314



 Score = 37.4 bits (85), Expect = 0.071
 Identities = 66/311 (21%), Positives = 92/311 (29%), Gaps = 37/311 (11%)

Query: 34  GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNP----DYSGTRSN 89
           G P  PG L  P   G +    +   +  P  PG+   P +P S   P     + G + +
Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559

Query: 90  AYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNP---DFAGSSSSGNY 146
                S  +P  P              P        P  PG +  P    F G       
Sbjct: 560 KGELGSPGAPGLP------------GLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGN 607

Query: 147 AGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPD 206
            G    P + G + P   G        G +    +PG +  +              GKP 
Sbjct: 608 PGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPG-QPGIPGPKGDPGQTITQPGKPG 666

Query: 207 YPGADIQPNSPPFFGEPDYPSAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGVLS 266
            PG   +       G+P  P       +P +  EP       G        PK   G+  
Sbjct: 667 LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIP----GIGLPGPPGPKGFPGIPG 722

Query: 267 RTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLPGAPGSGYVNPAYVG 326
              +     R   + P G        P G      E     G +LPG PG   + P + G
Sbjct: 723 PPGAPGTPGRIGLEGPPG--------PPGFPGPKGEP----GFALPGPPGPPGL-PGFKG 769

Query: 327 ESGPVHAYGNP 337
             GP    G P
Sbjct: 770 ALGPKGDRGFP 780



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 77/336 (22%), Positives = 103/336 (30%), Gaps = 64/336 (19%)

Query: 33  QGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAE--PNYPRSLSNPDYSGTRSNA 90
           +G+P + GP   P  PG       +     P +PG   +     P  +S P   G     
Sbjct: 373 RGFPGIQGPPGLPGPPGAA----VMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQP 428

Query: 91  YSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSR 150
             A     P  P     P   E            +P  PG   +P   G        G +
Sbjct: 429 -GAPGLPGPPGPAGPHIPPSDEI----------CEPGPPGPPGSPGDKGLQGEQGVKGDK 477

Query: 151 --THPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYP 208
             T  +  G+     PG       PGP  +L  PG +K  +  +    P     G P  P
Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG-QKGEKGQAGATGP----KGLPGIP 532

Query: 209 GADIQPNSPPFFGEP----DYPSAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGV 264
           GA   P  P   GEP     +P  + ++                  + GS   P +    
Sbjct: 533 GAPGAPGFPGSKGEPGDILTFPGMKGDKG-----------------ELGSPGAPGLPG-- 573

Query: 265 LSRTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLPGAPGS------- 317
           L  T            D +  L G    P GI     E        LPG PG+       
Sbjct: 574 LPGTP---------GQDGLPGLPGPKGEPGGITFKG-ERGPPGNPGLPGLPGNIGPMGPP 623

Query: 318 GYVNPAYVGESGPVHAYGNPPLSECDWHKSPQGQKL 353
           G+  P  VGE G     GNP        K   GQ +
Sbjct: 624 GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTI 659



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 46/208 (22%), Positives = 65/208 (31%), Gaps = 37/208 (17%)

Query: 27  QGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGT 86
           +G+   +G+P +PG      +PG    P     +     PG    P  P+ +  P   G 
Sbjct: 50  RGFPGLEGHPGLPG------FPGPEGPPGPRGQKGDDGIPG----PPGPKGIRGP--PGL 97

Query: 87  RSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNY 146
                +      P H    P P     Q  P    +  +  +PGS   P   G       
Sbjct: 98  PGFPGTPGLPGMPGH-DGAPGP-----QGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGI 151

Query: 147 AGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPD 206
            G +  P     +    PG + N  +PGP      PG                  +G P 
Sbjct: 152 PGMKGEPGSI--IMSSLPGPKGNPGYPGPPGIQGLPGP-----------TGIPGPIGPPG 198

Query: 207 YPGADIQPNSPPFFGEPDYPSAEDNQNL 234
            PG       PP  G P  P  + N  L
Sbjct: 199 PPGL----MGPP--GPPGLPGPKGNMGL 220



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 50/214 (23%), Positives = 61/214 (28%), Gaps = 45/214 (21%)

Query: 27  QGYLKTQGYPDVPGP-------LNNPDYPGTRSNPYS------------VASRTRPDYPG 67
           QG     G P +PGP       +  P  PG   NP                    P  PG
Sbjct: 637 QGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPG 696

Query: 68  SLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHP--TSLPEPDYSEFQSHPYHRASSRQ 125
           S  EP  P  +  P   G +          +P  P    L  P        P        
Sbjct: 697 SKGEPGIP-GIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755

Query: 126 PDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSR 185
           P  PG    P F G+       G R  P       P  PG       PGP+ ++   G  
Sbjct: 756 PGPPGPPGLPGFKGALGP---KGDRGFPG-----PPGPPGRTGLDGLPGPKGDVGPNGQ- 806

Query: 186 KNLEHTSFRINPYADSLGKPDYPGADIQ-PNSPP 218
                           +G P  PG  +Q P  PP
Sbjct: 807 -------------PGPMGPPGLPGIGVQGPPGPP 827



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 57/257 (22%), Positives = 69/257 (26%), Gaps = 37/257 (14%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPN 73
           P+ P     Q    G     G   + GP   P +PGT            P  PG      
Sbjct: 67  PEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGT------------PGLPGMPGHDG 114

Query: 74  YPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQR 133
            P     P  +GT+       S   P        P     +  P    S      PG + 
Sbjct: 115 APGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEP---GSIIMSSLPGPKG 171

Query: 134 NPDFAGSSSSGNYAGSRTHPDHFGSL-EPDYPGAQSNSDHPGPRAN--LNHPGSRKNLEH 190
           NP + G        G    P   G    P   G       PGP+ N  LN  G +     
Sbjct: 172 NPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGE 231

Query: 191 TSFRINP--------------YADSLGKPDYPGADIQPNSPPFFGEPDYPSAE----DNQ 232
              +  P                   G    PG    P  P   G P  P  E      Q
Sbjct: 232 QGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQ 291

Query: 233 NLPSTWREPDYSDAENG 249
             P    +P   D ENG
Sbjct: 292 GEPGKRGKPG-KDGENG 307



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 38/171 (22%), Positives = 50/171 (29%), Gaps = 25/171 (14%)

Query: 33  QGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNY--PRSLSNPDYSGTRSNA 90
           +G+P +PGP   P  PGT            P +PG   EP +  P     P   G +   
Sbjct: 715 KGFPGIPGP---PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL 771

Query: 91  YSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSG------ 144
                R  P  P     P  +     P  +        PG    P   G    G      
Sbjct: 772 GPKGDRGFPGPPGP---PGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828

Query: 145 -----------NYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGS 184
                         G +  P   G   P  PG + +   PG    +  PGS
Sbjct: 829 IPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGS 879


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 57/233 (24%), Positives = 79/233 (33%), Gaps = 17/233 (7%)

Query: 14   PDYPDYSGSQN--RTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPG---- 67
            P  P  +G+     T+G +   G P  PGPL  P   G          + +P  PG    
Sbjct: 880  PGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939

Query: 68   --SLAEPNYPRSLS--NPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASS 123
              S  EP  P      +P+  G++           P  P       Y      P     S
Sbjct: 940  KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL---PGIPGVSGPKGYQGLPGDPGQPGLS 996

Query: 124  RQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSL-EPDYPGAQSNSDHPGPRANLNHP 182
             QP  PG    P   G+       G    P   G++ +  +PG Q     PGP      P
Sbjct: 997  GQPGLPGP---PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQP 1053

Query: 183  GSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLP 235
            GS         + +P   S+G P  PG   +P  P + G P    +  +  LP
Sbjct: 1054 GSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLP 1106



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 53/213 (24%), Positives = 61/213 (28%), Gaps = 19/213 (8%)

Query: 34   GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSA 93
            G P +PGP   P  PG   NP    S   P  PG    P        P + GT       
Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133

Query: 94   ASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHP 153
                 P +P    EP       HP       QP  PG +  P   G        G    P
Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHP------GQPGPPGEKGKPGQDGIPGPAGQKGEPGQP 1187

Query: 154  DHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADS-LGKPDYPGADI 212
                   P  PG        G      +PG         F   P      G P  PG  +
Sbjct: 1188 GFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPAL 1247

Query: 213  Q-------PNSPPFFGEPDY---PSAEDNQNLP 235
            +       P  PP  G P +   P  E    LP
Sbjct: 1248 EGPKGNPGPQGPP--GRPGFQGLPGPEGPPGLP 1278



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 51/215 (23%), Positives = 71/215 (33%), Gaps = 20/215 (9%)

Query: 17  PDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPR 76
           P  +G++   +G+  + G+P + GP   P  PG +  P S+   + P   G+   P  P 
Sbjct: 122 PGCNGTKGE-RGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG 180

Query: 77  SLSNPDYSGTRS--NAYSAASRTSPDHPTSLPEPDYS---EFQSHPYHRASSRQPDYPGS 131
               P  +G               P  P  LP P  +    FQ     +         G 
Sbjct: 181 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQ------GL 234

Query: 132 QRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHT 191
           Q  P   G  S       R     F   +   PG +     PG R     PG  K  +  
Sbjct: 235 QGPPGPPGQISE----QKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGE 290

Query: 192 SFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYP 226
                      GKP   G + QP  P   G+P YP
Sbjct: 291 QGE----PGKRGKPGKDGENGQPGIPGLPGDPGYP 321



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 51/221 (23%), Positives = 65/221 (29%), Gaps = 33/221 (14%)

Query: 38  VPGPLNNPDYPGTRS-----NPYSVASRTRPDYPGSLAEPNYPRSLSNP------DYSGT 86
           +PGP  NP YPG         P  +     P  P  L  P  P  L  P      ++ G 
Sbjct: 166 LPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGP 225

Query: 87  RSNAYSAASRTSPDHPTSLPE---PDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSS 143
           +        +  P  P  + E   P   EFQ         R P  P   R P        
Sbjct: 226 KGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEK 285

Query: 144 GNYA-----GSRTHPDHFGSL----------EPDYPGAQSNSDHPGPRANLNHPGSRKNL 188
           G        G R  P   G            +P YPG        G + +   PG    +
Sbjct: 286 GEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLV 345

Query: 189 ---EHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYP 226
                T   I     ++G P  PG   +   P   G P  P
Sbjct: 346 IPRPGTGITIGE-KGNIGLPGLPGEKGERGFPGIQGPPGLP 385



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 49/205 (23%), Positives = 64/205 (31%), Gaps = 14/205 (6%)

Query: 34   GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSA 93
            G+P  PGP      PG    P     +  P  PG    P  P     P  SG + +    
Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG-FGNPGPP---GLPGLSGQKGDGGLP 1210

Query: 94   ASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHP 153
                +P  P    EP +  F   P  +     P  PG    P   G   +    G    P
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGF---PGVQGPPGPPGSPG----PALEGPKGNPGPQGPPGRP 1263

Query: 154  DHFGSLEPDYP-GAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYPGADI 212
               G   P+ P G   N    G + N   PG    L        P     G P  PG + 
Sbjct: 1264 GFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGL-PGLPGLKGDQGP-PGLQGNPGRPGLNG 1321

Query: 213  QPNSPPFFGEPDYPSAEDNQNLPST 237
                P   G P +P  +    +P +
Sbjct: 1322 MKGDPGLPGVPGFPGMKGPSGVPGS 1346



 Score = 38.5 bits (88), Expect = 0.032
 Identities = 54/236 (22%), Positives = 71/236 (30%), Gaps = 30/236 (12%)

Query: 13   DPDYPDYSGSQNRTQGYLKTQGYPDVPGP------LNNPDYPGTRSNPYSVASRTRPDYP 66
            DP  P   G+    +G     G+P  PGP         P  PG    P  V     P  P
Sbjct: 1102 DPGLPGLPGTPG-AKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQP 1160

Query: 67   GSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQP 126
            G   E   P     P  +G +           P  P     P           +     P
Sbjct: 1161 GPPGEKGKPGQDGIPGPAGQKG---------EPGQP-GFGNPGPPGLPGLSGQKGDGGLP 1210

Query: 127  DYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRK 186
              PG+   P   G      + G +  P   GS  P   G + N   PGP+     PG   
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGN---PGPQGPPGRPG--- 1264

Query: 187  NLEHTSFRINPYADS-LGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLPSTWREP 241
                  F+  P  +   G P   G   +  +P   G P  P  + +Q  P     P
Sbjct: 1265 ------FQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP 1314



 Score = 37.4 bits (85), Expect = 0.071
 Identities = 66/311 (21%), Positives = 92/311 (29%), Gaps = 37/311 (11%)

Query: 34  GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNP----DYSGTRSN 89
           G P  PG L  P   G +    +   +  P  PG+   P +P S   P     + G + +
Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559

Query: 90  AYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNP---DFAGSSSSGNY 146
                S  +P  P              P        P  PG +  P    F G       
Sbjct: 560 KGELGSPGAPGLP------------GLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGN 607

Query: 147 AGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPD 206
            G    P + G + P   G        G +    +PG +  +              GKP 
Sbjct: 608 PGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPG-QPGIPGPKGDPGQTITQPGKPG 666

Query: 207 YPGADIQPNSPPFFGEPDYPSAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGVLS 266
            PG   +       G+P  P       +P +  EP       G        PK   G+  
Sbjct: 667 LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIP----GIGLPGPPGPKGFPGIPG 722

Query: 267 RTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLPGAPGSGYVNPAYVG 326
              +     R   + P G        P G      E     G +LPG PG   + P + G
Sbjct: 723 PPGAPGTPGRIGLEGPPG--------PPGFPGPKGEP----GFALPGPPGPPGL-PGFKG 769

Query: 327 ESGPVHAYGNP 337
             GP    G P
Sbjct: 770 ALGPKGDRGFP 780



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 49/207 (23%), Positives = 62/207 (29%), Gaps = 35/207 (16%)

Query: 33   QGYPDVPGPLNN---------PDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLS---- 79
            +G P +PG   N         P  PG    P +      P +PG+   P  P+ +S    
Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG-PKGISGPPG 1140

Query: 80   NPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDY--PGSQRNPDF 137
            NP   G             P  P    +P           +    QP +  PG    P  
Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200

Query: 138  AGSSSSGNYAGSRTHPDHFGSL-EPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRIN 196
            +G    G   G   +P   G   EP + G       PGP      PGS            
Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP------PGS------------ 1242

Query: 197  PYADSLGKPDYPGADIQPNSPPFFGEP 223
            P     G    PG    P  P F G P
Sbjct: 1243 PGPALEGPKGNPGPQGPPGRPGFQGLP 1269



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 77/336 (22%), Positives = 103/336 (30%), Gaps = 64/336 (19%)

Query: 33  QGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAE--PNYPRSLSNPDYSGTRSNA 90
           +G+P + GP   P  PG       +     P +PG   +     P  +S P   G     
Sbjct: 373 RGFPGIQGPPGLPGPPGAA----VMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQP 428

Query: 91  YSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSR 150
             A     P  P     P   E            +P  PG   +P   G        G +
Sbjct: 429 -GAPGLPGPPGPAGPHIPPSDEI----------CEPGPPGPPGSPGDKGLQGEQGVKGDK 477

Query: 151 --THPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYP 208
             T  +  G+     PG       PGP  +L  PG +K  +  +    P     G P  P
Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG-QKGEKGQAGATGP----KGLPGIP 532

Query: 209 GADIQPNSPPFFGEP----DYPSAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGV 264
           GA   P  P   GEP     +P  + ++                  + GS   P +    
Sbjct: 533 GAPGAPGFPGSKGEPGDILTFPGMKGDKG-----------------ELGSPGAPGLPG-- 573

Query: 265 LSRTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLPGAPGS------- 317
           L  T            D +  L G    P GI     E        LPG PG+       
Sbjct: 574 LPGTP---------GQDGLPGLPGPKGEPGGITFKG-ERGPPGNPGLPGLPGNIGPMGPP 623

Query: 318 GYVNPAYVGESGPVHAYGNPPLSECDWHKSPQGQKL 353
           G+  P  VGE G     GNP        K   GQ +
Sbjct: 624 GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTI 659



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 46/208 (22%), Positives = 65/208 (31%), Gaps = 37/208 (17%)

Query: 27  QGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGT 86
           +G+   +G+P +PG      +PG    P     +     PG    P  P+ +  P   G 
Sbjct: 50  RGFPGLEGHPGLPG------FPGPEGPPGPRGQKGDDGIPG----PPGPKGIRGP--PGL 97

Query: 87  RSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNY 146
                +      P H    P P     Q  P    +  +  +PGS   P   G       
Sbjct: 98  PGFPGTPGLPGMPGH-DGAPGP-----QGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGI 151

Query: 147 AGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPD 206
            G +  P     +    PG + N  +PGP      PG                  +G P 
Sbjct: 152 PGMKGEPGSI--IMSSLPGPKGNPGYPGPPGIQGLPGP-----------TGIPGPIGPPG 198

Query: 207 YPGADIQPNSPPFFGEPDYPSAEDNQNL 234
            PG       PP  G P  P  + N  L
Sbjct: 199 PPGL----MGPP--GPPGLPGPKGNMGL 220



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 50/214 (23%), Positives = 61/214 (28%), Gaps = 45/214 (21%)

Query: 27  QGYLKTQGYPDVPGP-------LNNPDYPGTRSNPYS------------VASRTRPDYPG 67
           QG     G P +PGP       +  P  PG   NP                    P  PG
Sbjct: 637 QGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPG 696

Query: 68  SLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHP--TSLPEPDYSEFQSHPYHRASSRQ 125
           S  EP  P  +  P   G +          +P  P    L  P        P        
Sbjct: 697 SKGEPGIP-GIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755

Query: 126 PDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSR 185
           P  PG    P F G+       G R  P       P  PG       PGP+ ++   G  
Sbjct: 756 PGPPGPPGLPGFKGALGP---KGDRGFPG-----PPGPPGRTGLDGLPGPKGDVGPNGQ- 806

Query: 186 KNLEHTSFRINPYADSLGKPDYPGADIQ-PNSPP 218
                           +G P  PG  +Q P  PP
Sbjct: 807 -------------PGPMGPPGLPGIGVQGPPGPP 827



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 57/257 (22%), Positives = 69/257 (26%), Gaps = 37/257 (14%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPN 73
           P+ P     Q    G     G   + GP   P +PGT            P  PG      
Sbjct: 67  PEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGT------------PGLPGMPGHDG 114

Query: 74  YPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQR 133
            P     P  +GT+       S   P        P     +  P    S      PG + 
Sbjct: 115 APGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEP---GSIIMSSLPGPKG 171

Query: 134 NPDFAGSSSSGNYAGSRTHPDHFGSL-EPDYPGAQSNSDHPGPRAN--LNHPGSRKNLEH 190
           NP + G        G    P   G    P   G       PGP+ N  LN  G +     
Sbjct: 172 NPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGE 231

Query: 191 TSFRINP--------------YADSLGKPDYPGADIQPNSPPFFGEPDYPSAE----DNQ 232
              +  P                   G    PG    P  P   G P  P  E      Q
Sbjct: 232 QGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQ 291

Query: 233 NLPSTWREPDYSDAENG 249
             P    +P   D ENG
Sbjct: 292 GEPGKRGKPG-KDGENG 307



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 38/171 (22%), Positives = 50/171 (29%), Gaps = 25/171 (14%)

Query: 33  QGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNY--PRSLSNPDYSGTRSNA 90
           +G+P +PGP   P  PGT            P +PG   EP +  P     P   G +   
Sbjct: 715 KGFPGIPGP---PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL 771

Query: 91  YSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSG------ 144
                R  P  P     P  +     P  +        PG    P   G    G      
Sbjct: 772 GPKGDRGFPGPPGP---PGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828

Query: 145 -----------NYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGS 184
                         G +  P   G   P  PG + +   PG    +  PGS
Sbjct: 829 IPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGS 879


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
           sapiens]
          Length = 1424

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 42/176 (23%), Positives = 60/176 (34%), Gaps = 19/176 (10%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPN 73
           P  P  +G +          G P  PGP  +P   G    P S+     P  PG   EP 
Sbjct: 636 PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 74  YPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQR 133
            P  +  P   G + +     ++ S   P  + EP                +P  PG++ 
Sbjct: 696 IP-GIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP------------GLPGKPGLPGAKG 742

Query: 134 NPDFA--GSSSSGNYAGSRTHPDHFGSLE----PDYPGAQSNSDHPGPRANLNHPG 183
            P  A  G   +  + G R +    G +     P  PG   N    GPR +   PG
Sbjct: 743 EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG 798



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 66/297 (22%), Positives = 90/297 (30%), Gaps = 36/297 (12%)

Query: 39   PGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSAASRTS 98
            PG   +P  PG +     +  R  P  PG L  P     +    + G         +  +
Sbjct: 852  PGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGT 911

Query: 99   PDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGS 158
            P    S   P     +  P  +        PG        G        G   +P   G+
Sbjct: 912  PGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGN 971

Query: 159  L-EPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINP----YADSLGKPDYPGADIQ 213
               P  PG +     PGP      PG R +L  T     P       S+G    PG+  +
Sbjct: 972  RGVPGMPGLKGLKGLPGP---AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGK 1028

Query: 214  PNSPPFFGEPDYPSAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGVLSRTSSIQP 273
              +  F G    P       L     EP YS+       G +  P +   +  +    QP
Sbjct: 1029 RGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP 1088

Query: 274  SFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLPGAPGSGYVNPAYVGESGP 330
                    P G L      P G E A            PG+PGS    P   G+ GP
Sbjct: 1089 G-------PPGHLG-----PAGPEGA------------PGSPGS----PGLPGKPGP 1117



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 53/220 (24%), Positives = 67/220 (30%), Gaps = 50/220 (22%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPN 73
           P +P   G+     G +   G P +PG   N    G R +P           PG   E  
Sbjct: 755 PGFPGERGNSGE-HGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG- 812

Query: 74  YPRSLSN-PDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQ 132
            PR     P  +G +        +T P     +P  D S F               PG  
Sbjct: 813 -PRGAQGLPGLNGLKGQQ-GRRGKTGPKGDPGIPGLDRSGF---------------PGET 855

Query: 133 RNPDFAGSSSSGNYAGSRTHPDHFGSLEP----------DYPGAQSNSDHPGPRANLNHP 182
            +P   G        G R +P + G L P           +PGA      PGP  N   P
Sbjct: 856 GSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGA---IGPPGPPGNPGTP 912

Query: 183 GSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGE 222
           G R                 G P  PG   Q  +P   GE
Sbjct: 913 GQR-----------------GSPGIPGVKGQRGTPGAKGE 935



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 45/188 (23%), Positives = 56/188 (29%), Gaps = 40/188 (21%)

Query: 27   QGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGT 86
            +G L + G P  PG    P   G    P S   R    +PG    P  P         G 
Sbjct: 996  RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKG- 1054

Query: 87   RSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNY 146
                                EP YSE            +P  PG   +P   G       
Sbjct: 1055 --------------------EPGYSE----------GTRPGPPGPTGDPGLPGDMGKKGE 1084

Query: 147  AGSRTHPDHFGSLEPD----YPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSL 202
             G    P H G   P+     PG+      PGP  +L   G +  L     R  P     
Sbjct: 1085 MGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP----- 1139

Query: 203  GKPDYPGA 210
            G P +PG+
Sbjct: 1140 GLPGFPGS 1147



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 53/220 (24%), Positives = 70/220 (31%), Gaps = 38/220 (17%)

Query: 14   PDYPDYSGSQNRT--QGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAE 71
            P  P   G+      +G    +G+P  PG L     PG   N     SR  P  PG    
Sbjct: 1200 PGLPGRKGAMGDAGPRGPTGIEGFPGPPG-LPGAIIPGQTGNRGPPGSRGSPGAPGPPGP 1258

Query: 72   PNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGS 131
            P            G + +      + S  HP     P  +     P    +   P  PG 
Sbjct: 1259 PG-------SHVIGIKGD------KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGP 1305

Query: 132  QRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHT 191
            + +P F G        G + +P   GS+ P  PG       PG R +   PG+ K     
Sbjct: 1306 RGDPGFQGFPG---VKGEKGNPGFLGSIGP--PGPIGPKGPPGVRGD---PGTLK----- 1352

Query: 192  SFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDN 231
                      +  P  PG    P  P   GEP  P    N
Sbjct: 1353 ---------IISLPGSPGPPGTPGEPGMQGEPGPPGPPGN 1383



 Score = 37.7 bits (86), Expect = 0.055
 Identities = 64/260 (24%), Positives = 81/260 (31%), Gaps = 39/260 (15%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRS------NPYSVASRTRPDYPG 67
           P  P   G +    G L TQ  P +PGP   P  PG            +   +  P  PG
Sbjct: 460 PGIPGVDGPKGEP-GLLCTQ-CPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPG 517

Query: 68  SLAEPNYPR---SLSNPDYSGTRSNAYSAASRTS-PDHPTSLPEPDYSEFQSHPYHRASS 123
           +   P +P    +  +P   G +        +   P  P    +P        P      
Sbjct: 518 NTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVK 577

Query: 124 RQPD---------YPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHP- 173
             P            G Q  P   GS  S   AG    P +    EP   G Q     P 
Sbjct: 578 GLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG 637

Query: 174 -----GPRANLN-------HPGSRKNLEHTSFRINP-YADSLGK---PDYPGADIQPNSP 217
                GPR  L+        PG      H   +  P    SLGK   P  PG D +P  P
Sbjct: 638 PPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIP 697

Query: 218 PFFGEPDYPSAEDNQNLPST 237
              G P  P  + +Q  P T
Sbjct: 698 G-IGFPGPPGPKGDQGFPGT 716



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 51/218 (23%), Positives = 66/218 (30%), Gaps = 49/218 (22%)

Query: 28  GYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTR 87
           GYL + G P V GP   P    T+  PY       P  PG       P            
Sbjct: 455 GYLGSPGIPGVDGPKGEPGLLCTQC-PYIPGPPGLPGLPGLHGVKGIP------------ 501

Query: 88  SNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSS---- 143
               +A  + SP  P +   P +               P +PG+Q +P   G        
Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPGF---------------PGFPGAQGDPGLKGEKGETLQP 546

Query: 144 ------GNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINP 197
                     G R  P   G      PG       PGP+  L   G + +         P
Sbjct: 547 EGQVGVPGDPGLRGQPGRKGL--DGIPGTPGVKGLPGPKGELALSGEKGDQ-------GP 597

Query: 198 YADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLP 235
             D  G P  PG    P  PP +G    P  +  Q +P
Sbjct: 598 PGDP-GSPGSPG-PAGPAGPPGYGPQGEPGLQGTQGVP 633



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 54/211 (25%), Positives = 71/211 (33%), Gaps = 35/211 (16%)

Query: 28   GYLKTQGYPDV---PGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYS 84
            G +   G+P     PGP  NP  PG R +P     + +   PG+  E             
Sbjct: 889  GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGE------------Q 936

Query: 85   GTRSN-AYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYP---GSQRNPDFAGS 140
            G + N   S  S    D      EP    F  +P  + +   P  P   G +  P  AG 
Sbjct: 937  GDKGNPGPSEISHVIGDK----GEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 141  SSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHP---GPRANLNHPG--SRKNLEHTSFRI 195
                   GS  +P   G      PG+  N   P   G R  L  PG   R  L      I
Sbjct: 993  PGPRGDLGSTGNPGEPGL--RGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLP----GI 1046

Query: 196  NPYADSLGKPDYPGADIQPNSPPFFGEPDYP 226
            +      G+P Y     +P  P   G+P  P
Sbjct: 1047 HGLQGDKGEPGY-SEGTRPGPPGPTGDPGLP 1076



 Score = 35.4 bits (80), Expect = 0.27
 Identities = 48/200 (24%), Positives = 65/200 (32%), Gaps = 9/200 (4%)

Query: 34   GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSA 93
            G P + GP   P +PG+         + R   PG   E      L  P   G R N  + 
Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP--PGPRGNPGAQ 1188

Query: 94   ASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYA--GSRT 151
             ++     P     P           R  +    +PG    P       +GN    GSR 
Sbjct: 1189 GAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRG 1248

Query: 152  HPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYPGAD 211
             P   G+  P  P         G + ++ HPG  K    T+  + P    LG P  PG  
Sbjct: 1249 SP---GAPGPPGPPGSHVIGIKGDKGSMGHPGP-KGPPGTAGDMGP-PGRLGAPGTPGLP 1303

Query: 212  IQPNSPPFFGEPDYPSAEDN 231
                 P F G P     + N
Sbjct: 1304 GPRGDPGFQGFPGVKGEKGN 1323



 Score = 34.7 bits (78), Expect = 0.46
 Identities = 50/213 (23%), Positives = 67/213 (31%), Gaps = 17/213 (7%)

Query: 13  DPDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAE- 71
           +P  P  SG    + G  K  G P  PG    P   G    P S   +    +PG + E 
Sbjct: 269 EPGPPGPSGLPGESYGSEK--GAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGED 326

Query: 72  --PNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYP 129
                   +  P + G  +  Y        +     P P  +     P        P  P
Sbjct: 327 GIKGQKGDIGPPGFRGP-TEYYDTYQEKGDEGTPGPPGPRGARGPQGP--SGPPGVPGSP 383

Query: 130 GSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLE 189
           GS R P   G+       GS+      G      PG+   +  PG   +   PG   ++ 
Sbjct: 384 GSSR-PGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI- 441

Query: 190 HTSFRINPYADS-----LGKPDYPGADIQPNSP 217
              FR  P  D      LG P  PG D     P
Sbjct: 442 --VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 23/89 (25%), Positives = 33/89 (37%), Gaps = 5/89 (5%)

Query: 13   DPDYPDYSG--SQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLA 70
            DP +  + G   +    G+L + G    PGP+     PG R +P ++   + P  PG   
Sbjct: 1308 DPGFQGFPGVKGEKGNPGFLGSIG---PPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPG 1364

Query: 71   EPNYPRSLSNPDYSGTRSNAYSAASRTSP 99
             P  P     P   G   N      R  P
Sbjct: 1365 TPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 75/351 (21%), Positives = 103/351 (29%), Gaps = 49/351 (13%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSN--PYSVASRTRPDYPGSLAE 71
           P  P  +GS+         +G   +PG   +P  PGT  N  PY +     P   GS  E
Sbjct: 81  PGLPGLTGSKG-------VRGISGLPGFSGSPGLPGTPGNTGPYGLVGV--PGCSGSKGE 131

Query: 72  PNYPRSLSNPDYSGTRSNAYSAASRTSP--DHPTSLPEPDYSEFQSHPYHRASSRQPDYP 129
             +P       Y G    A     + +P  +    L           P  +     P +P
Sbjct: 132 QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP 191

Query: 130 GSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRA-------NLNHP 182
           G    P   G        G R    H G     + G +      GP          L  P
Sbjct: 192 GPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGP 251

Query: 183 GSRKNLEH----------------TSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYP 226
            +R +L+                 +      Y    G P  PG   +P      G P   
Sbjct: 252 DNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSE 311

Query: 227 SAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGVLSRTSSIQPSFRHRSDDPVGSL 286
             + N+  P    E D    + G D G    P   RG      + Q      +  P G  
Sbjct: 312 GVKGNRGFPGLMGE-DGIKGQKG-DIG----PPGFRGPTEYYDTYQEKGDEGTPGPPGPR 365

Query: 287 WGENDYPEGIEMASMEMANSYGHSLPGAPGSGYVNPAYVGESGPVHAYGNP 337
                 P+G       +  S G S PG  G+    P + G  G     G P
Sbjct: 366 GARG--PQG-PSGPPGVPGSPGSSRPGLRGA----PGWPGLKGSKGERGRP 409


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
           sapiens]
          Length = 1494

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 42/176 (23%), Positives = 60/176 (34%), Gaps = 19/176 (10%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPN 73
           P  P  +G +          G P  PGP  +P   G    P S+     P  PG   EP 
Sbjct: 636 PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 74  YPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQR 133
            P  +  P   G + +     ++ S   P  + EP                +P  PG++ 
Sbjct: 696 IP-GIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP------------GLPGKPGLPGAKG 742

Query: 134 NPDFA--GSSSSGNYAGSRTHPDHFGSLE----PDYPGAQSNSDHPGPRANLNHPG 183
            P  A  G   +  + G R +    G +     P  PG   N    GPR +   PG
Sbjct: 743 EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG 798



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 66/297 (22%), Positives = 90/297 (30%), Gaps = 36/297 (12%)

Query: 39   PGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSAASRTS 98
            PG   +P  PG +     +  R  P  PG L  P     +    + G         +  +
Sbjct: 852  PGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGT 911

Query: 99   PDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGS 158
            P    S   P     +  P  +        PG        G        G   +P   G+
Sbjct: 912  PGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGN 971

Query: 159  L-EPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINP----YADSLGKPDYPGADIQ 213
               P  PG +     PGP      PG R +L  T     P       S+G    PG+  +
Sbjct: 972  RGVPGMPGLKGLKGLPGP---AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGK 1028

Query: 214  PNSPPFFGEPDYPSAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGVLSRTSSIQP 273
              +  F G    P       L     EP YS+       G +  P +   +  +    QP
Sbjct: 1029 RGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP 1088

Query: 274  SFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLPGAPGSGYVNPAYVGESGP 330
                    P G L      P G E A            PG+PGS    P   G+ GP
Sbjct: 1089 G-------PPGHLG-----PAGPEGA------------PGSPGS----PGLPGKPGP 1117



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 53/220 (24%), Positives = 67/220 (30%), Gaps = 50/220 (22%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPN 73
           P +P   G+     G +   G P +PG   N    G R +P           PG   E  
Sbjct: 755 PGFPGERGNSGE-HGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG- 812

Query: 74  YPRSLSN-PDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQ 132
            PR     P  +G +        +T P     +P  D S F               PG  
Sbjct: 813 -PRGAQGLPGLNGLKGQQ-GRRGKTGPKGDPGIPGLDRSGF---------------PGET 855

Query: 133 RNPDFAGSSSSGNYAGSRTHPDHFGSLEP----------DYPGAQSNSDHPGPRANLNHP 182
            +P   G        G R +P + G L P           +PGA      PGP  N   P
Sbjct: 856 GSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGA---IGPPGPPGNPGTP 912

Query: 183 GSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGE 222
           G R                 G P  PG   Q  +P   GE
Sbjct: 913 GQR-----------------GSPGIPGVKGQRGTPGAKGE 935



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 45/188 (23%), Positives = 56/188 (29%), Gaps = 40/188 (21%)

Query: 27   QGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGT 86
            +G L + G P  PG    P   G    P S   R    +PG    P  P         G 
Sbjct: 996  RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKG- 1054

Query: 87   RSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNY 146
                                EP YSE            +P  PG   +P   G       
Sbjct: 1055 --------------------EPGYSE----------GTRPGPPGPTGDPGLPGDMGKKGE 1084

Query: 147  AGSRTHPDHFGSLEPD----YPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSL 202
             G    P H G   P+     PG+      PGP  +L   G +  L     R  P     
Sbjct: 1085 MGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP----- 1139

Query: 203  GKPDYPGA 210
            G P +PG+
Sbjct: 1140 GLPGFPGS 1147



 Score = 37.7 bits (86), Expect = 0.055
 Identities = 64/260 (24%), Positives = 81/260 (31%), Gaps = 39/260 (15%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRS------NPYSVASRTRPDYPG 67
           P  P   G +    G L TQ  P +PGP   P  PG            +   +  P  PG
Sbjct: 460 PGIPGVDGPKGEP-GLLCTQ-CPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPG 517

Query: 68  SLAEPNYPR---SLSNPDYSGTRSNAYSAASRTS-PDHPTSLPEPDYSEFQSHPYHRASS 123
           +   P +P    +  +P   G +        +   P  P    +P        P      
Sbjct: 518 NTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVK 577

Query: 124 RQPD---------YPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHP- 173
             P            G Q  P   GS  S   AG    P +    EP   G Q     P 
Sbjct: 578 GLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG 637

Query: 174 -----GPRANLN-------HPGSRKNLEHTSFRINP-YADSLGK---PDYPGADIQPNSP 217
                GPR  L+        PG      H   +  P    SLGK   P  PG D +P  P
Sbjct: 638 PPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIP 697

Query: 218 PFFGEPDYPSAEDNQNLPST 237
              G P  P  + +Q  P T
Sbjct: 698 G-IGFPGPPGPKGDQGFPGT 716



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 51/218 (23%), Positives = 66/218 (30%), Gaps = 49/218 (22%)

Query: 28  GYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTR 87
           GYL + G P V GP   P    T+  PY       P  PG       P            
Sbjct: 455 GYLGSPGIPGVDGPKGEPGLLCTQC-PYIPGPPGLPGLPGLHGVKGIP------------ 501

Query: 88  SNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSS---- 143
               +A  + SP  P +   P +               P +PG+Q +P   G        
Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPGF---------------PGFPGAQGDPGLKGEKGETLQP 546

Query: 144 ------GNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINP 197
                     G R  P   G      PG       PGP+  L   G + +         P
Sbjct: 547 EGQVGVPGDPGLRGQPGRKGL--DGIPGTPGVKGLPGPKGELALSGEKGDQ-------GP 597

Query: 198 YADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLP 235
             D  G P  PG    P  PP +G    P  +  Q +P
Sbjct: 598 PGDP-GSPGSPG-PAGPAGPPGYGPQGEPGLQGTQGVP 633



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 61/267 (22%), Positives = 78/267 (29%), Gaps = 67/267 (25%)

Query: 14   PDYPDYSGSQNRT--QGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAE 71
            P  P   G+      +G    +G+P  PG L     PG   N     SR  P  PG    
Sbjct: 1200 PGLPGRKGAMGDAGPRGPTGIEGFPGPPG-LPGAIIPGQTGNRGPPGSRGSPGAPGPPGP 1258

Query: 72   PN--------------YPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHP 117
            P               +P     P  +G         +  +P  P    +P +  F    
Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGF---- 1314

Query: 118  YHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSL----------------EP 161
                    P   G + NP F GS       G +  P   G                   P
Sbjct: 1315 --------PGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTP 1366

Query: 162  DYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFG 221
              PG Q     PGP  NL   G R           P  D  GKP  PG   +  +    G
Sbjct: 1367 GEPGMQGEPGPPGPPGNLGPCGPRG---------KPGKD--GKPGTPGPAGEKGNKGSKG 1415

Query: 222  EPDYPSAED----------NQNLPSTW 238
            EP  P+  D          +   P+TW
Sbjct: 1416 EPG-PAGSDGLPGLKGKRGDSGSPATW 1441



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 54/211 (25%), Positives = 71/211 (33%), Gaps = 35/211 (16%)

Query: 28   GYLKTQGYPDV---PGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYS 84
            G +   G+P     PGP  NP  PG R +P     + +   PG+  E             
Sbjct: 889  GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGE------------Q 936

Query: 85   GTRSN-AYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYP---GSQRNPDFAGS 140
            G + N   S  S    D      EP    F  +P  + +   P  P   G +  P  AG 
Sbjct: 937  GDKGNPGPSEISHVIGDK----GEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 141  SSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHP---GPRANLNHPG--SRKNLEHTSFRI 195
                   GS  +P   G      PG+  N   P   G R  L  PG   R  L      I
Sbjct: 993  PGPRGDLGSTGNPGEPGL--RGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLP----GI 1046

Query: 196  NPYADSLGKPDYPGADIQPNSPPFFGEPDYP 226
            +      G+P Y     +P  P   G+P  P
Sbjct: 1047 HGLQGDKGEPGY-SEGTRPGPPGPTGDPGLP 1076



 Score = 35.4 bits (80), Expect = 0.27
 Identities = 48/200 (24%), Positives = 65/200 (32%), Gaps = 9/200 (4%)

Query: 34   GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSA 93
            G P + GP   P +PG+         + R   PG   E      L  P   G R N  + 
Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP--PGPRGNPGAQ 1188

Query: 94   ASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYA--GSRT 151
             ++     P     P           R  +    +PG    P       +GN    GSR 
Sbjct: 1189 GAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRG 1248

Query: 152  HPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYPGAD 211
             P   G+  P  P         G + ++ HPG  K    T+  + P    LG P  PG  
Sbjct: 1249 SP---GAPGPPGPPGSHVIGIKGDKGSMGHPGP-KGPPGTAGDMGP-PGRLGAPGTPGLP 1303

Query: 212  IQPNSPPFFGEPDYPSAEDN 231
                 P F G P     + N
Sbjct: 1304 GPRGDPGFQGFPGVKGEKGN 1323



 Score = 34.7 bits (78), Expect = 0.46
 Identities = 50/213 (23%), Positives = 67/213 (31%), Gaps = 17/213 (7%)

Query: 13  DPDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAE- 71
           +P  P  SG    + G  K  G P  PG    P   G    P S   +    +PG + E 
Sbjct: 269 EPGPPGPSGLPGESYGSEK--GAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGED 326

Query: 72  --PNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYP 129
                   +  P + G  +  Y        +     P P  +     P        P  P
Sbjct: 327 GIKGQKGDIGPPGFRGP-TEYYDTYQEKGDEGTPGPPGPRGARGPQGP--SGPPGVPGSP 383

Query: 130 GSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLE 189
           GS R P   G+       GS+      G      PG+   +  PG   +   PG   ++ 
Sbjct: 384 GSSR-PGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI- 441

Query: 190 HTSFRINPYADS-----LGKPDYPGADIQPNSP 217
              FR  P  D      LG P  PG D     P
Sbjct: 442 --VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472



 Score = 34.3 bits (77), Expect = 0.61
 Identities = 32/131 (24%), Positives = 45/131 (34%), Gaps = 12/131 (9%)

Query: 13   DPDYPDYSG--SQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLA 70
            DP +  + G   +    G+L + G    PGP+     PG R +P ++   + P  PG   
Sbjct: 1308 DPGFQGFPGVKGEKGNPGFLGSIG---PPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPG 1364

Query: 71   EPNYPRSLSNPDYSGTRSNAYSAASRTSP--DHPTSLPEPDYSEFQSHPYHRASSRQPDY 128
             P  P     P   G   N      R  P  D     P P          ++ S  +P  
Sbjct: 1365 TPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP-----AGEKGNKGSKGEPGP 1419

Query: 129  PGSQRNPDFAG 139
             GS   P   G
Sbjct: 1420 AGSDGLPGLKG 1430



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 75/351 (21%), Positives = 103/351 (29%), Gaps = 49/351 (13%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSN--PYSVASRTRPDYPGSLAE 71
           P  P  +GS+         +G   +PG   +P  PGT  N  PY +     P   GS  E
Sbjct: 81  PGLPGLTGSKG-------VRGISGLPGFSGSPGLPGTPGNTGPYGLVGV--PGCSGSKGE 131

Query: 72  PNYPRSLSNPDYSGTRSNAYSAASRTSP--DHPTSLPEPDYSEFQSHPYHRASSRQPDYP 129
             +P       Y G    A     + +P  +    L           P  +     P +P
Sbjct: 132 QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP 191

Query: 130 GSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRA-------NLNHP 182
           G    P   G        G R    H G     + G +      GP          L  P
Sbjct: 192 GPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGP 251

Query: 183 GSRKNLEH----------------TSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYP 226
            +R +L+                 +      Y    G P  PG   +P      G P   
Sbjct: 252 DNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSE 311

Query: 227 SAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGVLSRTSSIQPSFRHRSDDPVGSL 286
             + N+  P    E D    + G D G    P   RG      + Q      +  P G  
Sbjct: 312 GVKGNRGFPGLMGE-DGIKGQKG-DIG----PPGFRGPTEYYDTYQEKGDEGTPGPPGPR 365

Query: 287 WGENDYPEGIEMASMEMANSYGHSLPGAPGSGYVNPAYVGESGPVHAYGNP 337
                 P+G       +  S G S PG  G+    P + G  G     G P
Sbjct: 366 GARG--PQG-PSGPPGVPGSPGSSRPGLRGA----PGWPGLKGSKGERGRP 409


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1637

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 42/176 (23%), Positives = 60/176 (34%), Gaps = 19/176 (10%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPN 73
           P  P  +G +          G P  PGP  +P   G    P S+     P  PG   EP 
Sbjct: 636 PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 74  YPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQR 133
            P  +  P   G + +     ++ S   P  + EP                +P  PG++ 
Sbjct: 696 IP-GIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP------------GLPGKPGLPGAKG 742

Query: 134 NPDFA--GSSSSGNYAGSRTHPDHFGSLE----PDYPGAQSNSDHPGPRANLNHPG 183
            P  A  G   +  + G R +    G +     P  PG   N    GPR +   PG
Sbjct: 743 EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG 798



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 66/297 (22%), Positives = 90/297 (30%), Gaps = 36/297 (12%)

Query: 39   PGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSAASRTS 98
            PG   +P  PG +     +  R  P  PG L  P     +    + G         +  +
Sbjct: 852  PGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGT 911

Query: 99   PDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGS 158
            P    S   P     +  P  +        PG        G        G   +P   G+
Sbjct: 912  PGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGN 971

Query: 159  L-EPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINP----YADSLGKPDYPGADIQ 213
               P  PG +     PGP      PG R +L  T     P       S+G    PG+  +
Sbjct: 972  RGVPGMPGLKGLKGLPGP---AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGK 1028

Query: 214  PNSPPFFGEPDYPSAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGVLSRTSSIQP 273
              +  F G    P       L     EP YS+       G +  P +   +  +    QP
Sbjct: 1029 RGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP 1088

Query: 274  SFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLPGAPGSGYVNPAYVGESGP 330
                    P G L      P G E A            PG+PGS    P   G+ GP
Sbjct: 1089 G-------PPGHLG-----PAGPEGA------------PGSPGS----PGLPGKPGP 1117



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 53/220 (24%), Positives = 67/220 (30%), Gaps = 50/220 (22%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPN 73
           P +P   G+     G +   G P +PG   N    G R +P           PG   E  
Sbjct: 755 PGFPGERGNSGE-HGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG- 812

Query: 74  YPRSLSN-PDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQ 132
            PR     P  +G +        +T P     +P  D S F               PG  
Sbjct: 813 -PRGAQGLPGLNGLKGQQ-GRRGKTGPKGDPGIPGLDRSGF---------------PGET 855

Query: 133 RNPDFAGSSSSGNYAGSRTHPDHFGSLEP----------DYPGAQSNSDHPGPRANLNHP 182
            +P   G        G R +P + G L P           +PGA      PGP  N   P
Sbjct: 856 GSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGA---IGPPGPPGNPGTP 912

Query: 183 GSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGE 222
           G R                 G P  PG   Q  +P   GE
Sbjct: 913 GQR-----------------GSPGIPGVKGQRGTPGAKGE 935



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 45/188 (23%), Positives = 56/188 (29%), Gaps = 40/188 (21%)

Query: 27   QGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGT 86
            +G L + G P  PG    P   G    P S   R    +PG    P  P         G 
Sbjct: 996  RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKG- 1054

Query: 87   RSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNY 146
                                EP YSE            +P  PG   +P   G       
Sbjct: 1055 --------------------EPGYSE----------GTRPGPPGPTGDPGLPGDMGKKGE 1084

Query: 147  AGSRTHPDHFGSLEPD----YPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSL 202
             G    P H G   P+     PG+      PGP  +L   G +  L     R  P     
Sbjct: 1085 MGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP----- 1139

Query: 203  GKPDYPGA 210
            G P +PG+
Sbjct: 1140 GLPGFPGS 1147



 Score = 37.7 bits (86), Expect = 0.055
 Identities = 64/260 (24%), Positives = 81/260 (31%), Gaps = 39/260 (15%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRS------NPYSVASRTRPDYPG 67
           P  P   G +    G L TQ  P +PGP   P  PG            +   +  P  PG
Sbjct: 460 PGIPGVDGPKGEP-GLLCTQ-CPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPG 517

Query: 68  SLAEPNYPR---SLSNPDYSGTRSNAYSAASRTS-PDHPTSLPEPDYSEFQSHPYHRASS 123
           +   P +P    +  +P   G +        +   P  P    +P        P      
Sbjct: 518 NTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVK 577

Query: 124 RQPD---------YPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHP- 173
             P            G Q  P   GS  S   AG    P +    EP   G Q     P 
Sbjct: 578 GLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG 637

Query: 174 -----GPRANLN-------HPGSRKNLEHTSFRINP-YADSLGK---PDYPGADIQPNSP 217
                GPR  L+        PG      H   +  P    SLGK   P  PG D +P  P
Sbjct: 638 PPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIP 697

Query: 218 PFFGEPDYPSAEDNQNLPST 237
              G P  P  + +Q  P T
Sbjct: 698 G-IGFPGPPGPKGDQGFPGT 716



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 51/218 (23%), Positives = 66/218 (30%), Gaps = 49/218 (22%)

Query: 28  GYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTR 87
           GYL + G P V GP   P    T+  PY       P  PG       P            
Sbjct: 455 GYLGSPGIPGVDGPKGEPGLLCTQC-PYIPGPPGLPGLPGLHGVKGIP------------ 501

Query: 88  SNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSS---- 143
               +A  + SP  P +   P +               P +PG+Q +P   G        
Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPGF---------------PGFPGAQGDPGLKGEKGETLQP 546

Query: 144 ------GNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINP 197
                     G R  P   G      PG       PGP+  L   G + +         P
Sbjct: 547 EGQVGVPGDPGLRGQPGRKGL--DGIPGTPGVKGLPGPKGELALSGEKGDQ-------GP 597

Query: 198 YADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLP 235
             D  G P  PG    P  PP +G    P  +  Q +P
Sbjct: 598 PGDP-GSPGSPG-PAGPAGPPGYGPQGEPGLQGTQGVP 633



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 61/267 (22%), Positives = 78/267 (29%), Gaps = 67/267 (25%)

Query: 14   PDYPDYSGSQNRT--QGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAE 71
            P  P   G+      +G    +G+P  PG L     PG   N     SR  P  PG    
Sbjct: 1200 PGLPGRKGAMGDAGPRGPTGIEGFPGPPG-LPGAIIPGQTGNRGPPGSRGSPGAPGPPGP 1258

Query: 72   PN--------------YPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHP 117
            P               +P     P  +G         +  +P  P    +P +  F    
Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGF---- 1314

Query: 118  YHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSL----------------EP 161
                    P   G + NP F GS       G +  P   G                   P
Sbjct: 1315 --------PGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTP 1366

Query: 162  DYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFG 221
              PG Q     PGP  NL   G R           P  D  GKP  PG   +  +    G
Sbjct: 1367 GEPGMQGEPGPPGPPGNLGPCGPRG---------KPGKD--GKPGTPGPAGEKGNKGSKG 1415

Query: 222  EPDYPSAED----------NQNLPSTW 238
            EP  P+  D          +   P+TW
Sbjct: 1416 EPG-PAGSDGLPGLKGKRGDSGSPATW 1441



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 54/211 (25%), Positives = 71/211 (33%), Gaps = 35/211 (16%)

Query: 28   GYLKTQGYPDV---PGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYS 84
            G +   G+P     PGP  NP  PG R +P     + +   PG+  E             
Sbjct: 889  GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGE------------Q 936

Query: 85   GTRSN-AYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYP---GSQRNPDFAGS 140
            G + N   S  S    D      EP    F  +P  + +   P  P   G +  P  AG 
Sbjct: 937  GDKGNPGPSEISHVIGDK----GEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 141  SSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHP---GPRANLNHPG--SRKNLEHTSFRI 195
                   GS  +P   G      PG+  N   P   G R  L  PG   R  L      I
Sbjct: 993  PGPRGDLGSTGNPGEPGL--RGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLP----GI 1046

Query: 196  NPYADSLGKPDYPGADIQPNSPPFFGEPDYP 226
            +      G+P Y     +P  P   G+P  P
Sbjct: 1047 HGLQGDKGEPGY-SEGTRPGPPGPTGDPGLP 1076



 Score = 35.4 bits (80), Expect = 0.27
 Identities = 48/200 (24%), Positives = 65/200 (32%), Gaps = 9/200 (4%)

Query: 34   GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSA 93
            G P + GP   P +PG+         + R   PG   E      L  P   G R N  + 
Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP--PGPRGNPGAQ 1188

Query: 94   ASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYA--GSRT 151
             ++     P     P           R  +    +PG    P       +GN    GSR 
Sbjct: 1189 GAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRG 1248

Query: 152  HPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYPGAD 211
             P   G+  P  P         G + ++ HPG  K    T+  + P    LG P  PG  
Sbjct: 1249 SP---GAPGPPGPPGSHVIGIKGDKGSMGHPGP-KGPPGTAGDMGP-PGRLGAPGTPGLP 1303

Query: 212  IQPNSPPFFGEPDYPSAEDN 231
                 P F G P     + N
Sbjct: 1304 GPRGDPGFQGFPGVKGEKGN 1323



 Score = 34.7 bits (78), Expect = 0.46
 Identities = 50/213 (23%), Positives = 67/213 (31%), Gaps = 17/213 (7%)

Query: 13  DPDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAE- 71
           +P  P  SG    + G  K  G P  PG    P   G    P S   +    +PG + E 
Sbjct: 269 EPGPPGPSGLPGESYGSEK--GAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGED 326

Query: 72  --PNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYP 129
                   +  P + G  +  Y        +     P P  +     P        P  P
Sbjct: 327 GIKGQKGDIGPPGFRGP-TEYYDTYQEKGDEGTPGPPGPRGARGPQGP--SGPPGVPGSP 383

Query: 130 GSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLE 189
           GS R P   G+       GS+      G      PG+   +  PG   +   PG   ++ 
Sbjct: 384 GSSR-PGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI- 441

Query: 190 HTSFRINPYADS-----LGKPDYPGADIQPNSP 217
              FR  P  D      LG P  PG D     P
Sbjct: 442 --VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472



 Score = 34.3 bits (77), Expect = 0.61
 Identities = 32/131 (24%), Positives = 45/131 (34%), Gaps = 12/131 (9%)

Query: 13   DPDYPDYSG--SQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLA 70
            DP +  + G   +    G+L + G    PGP+     PG R +P ++   + P  PG   
Sbjct: 1308 DPGFQGFPGVKGEKGNPGFLGSIG---PPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPG 1364

Query: 71   EPNYPRSLSNPDYSGTRSNAYSAASRTSP--DHPTSLPEPDYSEFQSHPYHRASSRQPDY 128
             P  P     P   G   N      R  P  D     P P          ++ S  +P  
Sbjct: 1365 TPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP-----AGEKGNKGSKGEPGP 1419

Query: 129  PGSQRNPDFAG 139
             GS   P   G
Sbjct: 1420 AGSDGLPGLKG 1430



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 75/351 (21%), Positives = 103/351 (29%), Gaps = 49/351 (13%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSN--PYSVASRTRPDYPGSLAE 71
           P  P  +GS+         +G   +PG   +P  PGT  N  PY +     P   GS  E
Sbjct: 81  PGLPGLTGSKG-------VRGISGLPGFSGSPGLPGTPGNTGPYGLVGV--PGCSGSKGE 131

Query: 72  PNYPRSLSNPDYSGTRSNAYSAASRTSP--DHPTSLPEPDYSEFQSHPYHRASSRQPDYP 129
             +P       Y G    A     + +P  +    L           P  +     P +P
Sbjct: 132 QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP 191

Query: 130 GSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRA-------NLNHP 182
           G    P   G        G R    H G     + G +      GP          L  P
Sbjct: 192 GPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGP 251

Query: 183 GSRKNLEH----------------TSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYP 226
            +R +L+                 +      Y    G P  PG   +P      G P   
Sbjct: 252 DNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSE 311

Query: 227 SAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGVLSRTSSIQPSFRHRSDDPVGSL 286
             + N+  P    E D    + G D G    P   RG      + Q      +  P G  
Sbjct: 312 GVKGNRGFPGLMGE-DGIKGQKG-DIG----PPGFRGPTEYYDTYQEKGDEGTPGPPGPR 365

Query: 287 WGENDYPEGIEMASMEMANSYGHSLPGAPGSGYVNPAYVGESGPVHAYGNP 337
                 P+G       +  S G S PG  G+    P + G  G     G P
Sbjct: 366 GARG--PQG-PSGPPGVPGSPGSSRPGLRGA----PGWPGLKGSKGERGRP 409


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1670

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 42/176 (23%), Positives = 60/176 (34%), Gaps = 19/176 (10%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPN 73
           P  P  +G +          G P  PGP  +P   G    P S+     P  PG   EP 
Sbjct: 636 PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 74  YPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQR 133
            P  +  P   G + +     ++ S   P  + EP                +P  PG++ 
Sbjct: 696 IP-GIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP------------GLPGKPGLPGAKG 742

Query: 134 NPDFA--GSSSSGNYAGSRTHPDHFGSLE----PDYPGAQSNSDHPGPRANLNHPG 183
            P  A  G   +  + G R +    G +     P  PG   N    GPR +   PG
Sbjct: 743 EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG 798



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 66/297 (22%), Positives = 90/297 (30%), Gaps = 36/297 (12%)

Query: 39   PGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSAASRTS 98
            PG   +P  PG +     +  R  P  PG L  P     +    + G         +  +
Sbjct: 852  PGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGT 911

Query: 99   PDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGS 158
            P    S   P     +  P  +        PG        G        G   +P   G+
Sbjct: 912  PGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGN 971

Query: 159  L-EPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINP----YADSLGKPDYPGADIQ 213
               P  PG +     PGP      PG R +L  T     P       S+G    PG+  +
Sbjct: 972  RGVPGMPGLKGLKGLPGP---AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGK 1028

Query: 214  PNSPPFFGEPDYPSAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGVLSRTSSIQP 273
              +  F G    P       L     EP YS+       G +  P +   +  +    QP
Sbjct: 1029 RGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP 1088

Query: 274  SFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLPGAPGSGYVNPAYVGESGP 330
                    P G L      P G E A            PG+PGS    P   G+ GP
Sbjct: 1089 G-------PPGHLG-----PAGPEGA------------PGSPGS----PGLPGKPGP 1117



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 53/220 (24%), Positives = 67/220 (30%), Gaps = 50/220 (22%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPN 73
           P +P   G+     G +   G P +PG   N    G R +P           PG   E  
Sbjct: 755 PGFPGERGNSGE-HGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG- 812

Query: 74  YPRSLSN-PDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQ 132
            PR     P  +G +        +T P     +P  D S F               PG  
Sbjct: 813 -PRGAQGLPGLNGLKGQQ-GRRGKTGPKGDPGIPGLDRSGF---------------PGET 855

Query: 133 RNPDFAGSSSSGNYAGSRTHPDHFGSLEP----------DYPGAQSNSDHPGPRANLNHP 182
            +P   G        G R +P + G L P           +PGA      PGP  N   P
Sbjct: 856 GSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGA---IGPPGPPGNPGTP 912

Query: 183 GSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGE 222
           G R                 G P  PG   Q  +P   GE
Sbjct: 913 GQR-----------------GSPGIPGVKGQRGTPGAKGE 935



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 45/188 (23%), Positives = 56/188 (29%), Gaps = 40/188 (21%)

Query: 27   QGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGT 86
            +G L + G P  PG    P   G    P S   R    +PG    P  P         G 
Sbjct: 996  RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKG- 1054

Query: 87   RSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNY 146
                                EP YSE            +P  PG   +P   G       
Sbjct: 1055 --------------------EPGYSE----------GTRPGPPGPTGDPGLPGDMGKKGE 1084

Query: 147  AGSRTHPDHFGSLEPD----YPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSL 202
             G    P H G   P+     PG+      PGP  +L   G +  L     R  P     
Sbjct: 1085 MGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP----- 1139

Query: 203  GKPDYPGA 210
            G P +PG+
Sbjct: 1140 GLPGFPGS 1147



 Score = 37.7 bits (86), Expect = 0.055
 Identities = 64/260 (24%), Positives = 81/260 (31%), Gaps = 39/260 (15%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRS------NPYSVASRTRPDYPG 67
           P  P   G +    G L TQ  P +PGP   P  PG            +   +  P  PG
Sbjct: 460 PGIPGVDGPKGEP-GLLCTQ-CPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPG 517

Query: 68  SLAEPNYPR---SLSNPDYSGTRSNAYSAASRTS-PDHPTSLPEPDYSEFQSHPYHRASS 123
           +   P +P    +  +P   G +        +   P  P    +P        P      
Sbjct: 518 NTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVK 577

Query: 124 RQPD---------YPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHP- 173
             P            G Q  P   GS  S   AG    P +    EP   G Q     P 
Sbjct: 578 GLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG 637

Query: 174 -----GPRANLN-------HPGSRKNLEHTSFRINP-YADSLGK---PDYPGADIQPNSP 217
                GPR  L+        PG      H   +  P    SLGK   P  PG D +P  P
Sbjct: 638 PPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIP 697

Query: 218 PFFGEPDYPSAEDNQNLPST 237
              G P  P  + +Q  P T
Sbjct: 698 G-IGFPGPPGPKGDQGFPGT 716



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 51/218 (23%), Positives = 66/218 (30%), Gaps = 49/218 (22%)

Query: 28  GYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTR 87
           GYL + G P V GP   P    T+  PY       P  PG       P            
Sbjct: 455 GYLGSPGIPGVDGPKGEPGLLCTQC-PYIPGPPGLPGLPGLHGVKGIP------------ 501

Query: 88  SNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSS---- 143
               +A  + SP  P +   P +               P +PG+Q +P   G        
Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPGF---------------PGFPGAQGDPGLKGEKGETLQP 546

Query: 144 ------GNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINP 197
                     G R  P   G      PG       PGP+  L   G + +         P
Sbjct: 547 EGQVGVPGDPGLRGQPGRKGL--DGIPGTPGVKGLPGPKGELALSGEKGDQ-------GP 597

Query: 198 YADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLP 235
             D  G P  PG    P  PP +G    P  +  Q +P
Sbjct: 598 PGDP-GSPGSPG-PAGPAGPPGYGPQGEPGLQGTQGVP 633



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 61/267 (22%), Positives = 78/267 (29%), Gaps = 67/267 (25%)

Query: 14   PDYPDYSGSQNRT--QGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAE 71
            P  P   G+      +G    +G+P  PG L     PG   N     SR  P  PG    
Sbjct: 1200 PGLPGRKGAMGDAGPRGPTGIEGFPGPPG-LPGAIIPGQTGNRGPPGSRGSPGAPGPPGP 1258

Query: 72   PN--------------YPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHP 117
            P               +P     P  +G         +  +P  P    +P +  F    
Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGF---- 1314

Query: 118  YHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSL----------------EP 161
                    P   G + NP F GS       G +  P   G                   P
Sbjct: 1315 --------PGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTP 1366

Query: 162  DYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFG 221
              PG Q     PGP  NL   G R           P  D  GKP  PG   +  +    G
Sbjct: 1367 GEPGMQGEPGPPGPPGNLGPCGPRG---------KPGKD--GKPGTPGPAGEKGNKGSKG 1415

Query: 222  EPDYPSAED----------NQNLPSTW 238
            EP  P+  D          +   P+TW
Sbjct: 1416 EPG-PAGSDGLPGLKGKRGDSGSPATW 1441



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 54/211 (25%), Positives = 71/211 (33%), Gaps = 35/211 (16%)

Query: 28   GYLKTQGYPDV---PGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYS 84
            G +   G+P     PGP  NP  PG R +P     + +   PG+  E             
Sbjct: 889  GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGE------------Q 936

Query: 85   GTRSN-AYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYP---GSQRNPDFAGS 140
            G + N   S  S    D      EP    F  +P  + +   P  P   G +  P  AG 
Sbjct: 937  GDKGNPGPSEISHVIGDK----GEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 141  SSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHP---GPRANLNHPG--SRKNLEHTSFRI 195
                   GS  +P   G      PG+  N   P   G R  L  PG   R  L      I
Sbjct: 993  PGPRGDLGSTGNPGEPGL--RGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLP----GI 1046

Query: 196  NPYADSLGKPDYPGADIQPNSPPFFGEPDYP 226
            +      G+P Y     +P  P   G+P  P
Sbjct: 1047 HGLQGDKGEPGY-SEGTRPGPPGPTGDPGLP 1076



 Score = 35.4 bits (80), Expect = 0.27
 Identities = 48/200 (24%), Positives = 65/200 (32%), Gaps = 9/200 (4%)

Query: 34   GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSA 93
            G P + GP   P +PG+         + R   PG   E      L  P   G R N  + 
Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP--PGPRGNPGAQ 1188

Query: 94   ASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYA--GSRT 151
             ++     P     P           R  +    +PG    P       +GN    GSR 
Sbjct: 1189 GAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRG 1248

Query: 152  HPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYPGAD 211
             P   G+  P  P         G + ++ HPG  K    T+  + P    LG P  PG  
Sbjct: 1249 SP---GAPGPPGPPGSHVIGIKGDKGSMGHPGP-KGPPGTAGDMGP-PGRLGAPGTPGLP 1303

Query: 212  IQPNSPPFFGEPDYPSAEDN 231
                 P F G P     + N
Sbjct: 1304 GPRGDPGFQGFPGVKGEKGN 1323



 Score = 34.7 bits (78), Expect = 0.46
 Identities = 50/213 (23%), Positives = 67/213 (31%), Gaps = 17/213 (7%)

Query: 13  DPDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAE- 71
           +P  P  SG    + G  K  G P  PG    P   G    P S   +    +PG + E 
Sbjct: 269 EPGPPGPSGLPGESYGSEK--GAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGED 326

Query: 72  --PNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYP 129
                   +  P + G  +  Y        +     P P  +     P        P  P
Sbjct: 327 GIKGQKGDIGPPGFRGP-TEYYDTYQEKGDEGTPGPPGPRGARGPQGP--SGPPGVPGSP 383

Query: 130 GSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLE 189
           GS R P   G+       GS+      G      PG+   +  PG   +   PG   ++ 
Sbjct: 384 GSSR-PGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDI- 441

Query: 190 HTSFRINPYADS-----LGKPDYPGADIQPNSP 217
              FR  P  D      LG P  PG D     P
Sbjct: 442 --VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472



 Score = 34.3 bits (77), Expect = 0.61
 Identities = 32/131 (24%), Positives = 45/131 (34%), Gaps = 12/131 (9%)

Query: 13   DPDYPDYSG--SQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLA 70
            DP +  + G   +    G+L + G    PGP+     PG R +P ++   + P  PG   
Sbjct: 1308 DPGFQGFPGVKGEKGNPGFLGSIG---PPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPG 1364

Query: 71   EPNYPRSLSNPDYSGTRSNAYSAASRTSP--DHPTSLPEPDYSEFQSHPYHRASSRQPDY 128
             P  P     P   G   N      R  P  D     P P          ++ S  +P  
Sbjct: 1365 TPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP-----AGEKGNKGSKGEPGP 1419

Query: 129  PGSQRNPDFAG 139
             GS   P   G
Sbjct: 1420 AGSDGLPGLKG 1430



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 75/351 (21%), Positives = 103/351 (29%), Gaps = 49/351 (13%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSN--PYSVASRTRPDYPGSLAE 71
           P  P  +GS+         +G   +PG   +P  PGT  N  PY +     P   GS  E
Sbjct: 81  PGLPGLTGSKG-------VRGISGLPGFSGSPGLPGTPGNTGPYGLVGV--PGCSGSKGE 131

Query: 72  PNYPRSLSNPDYSGTRSNAYSAASRTSP--DHPTSLPEPDYSEFQSHPYHRASSRQPDYP 129
             +P       Y G    A     + +P  +    L           P  +     P +P
Sbjct: 132 QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP 191

Query: 130 GSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRA-------NLNHP 182
           G    P   G        G R    H G     + G +      GP          L  P
Sbjct: 192 GPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGP 251

Query: 183 GSRKNLEH----------------TSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYP 226
            +R +L+                 +      Y    G P  PG   +P      G P   
Sbjct: 252 DNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSE 311

Query: 227 SAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGVLSRTSSIQPSFRHRSDDPVGSL 286
             + N+  P    E D    + G D G    P   RG      + Q      +  P G  
Sbjct: 312 GVKGNRGFPGLMGE-DGIKGQKG-DIG----PPGFRGPTEYYDTYQEKGDEGTPGPPGPR 365

Query: 287 WGENDYPEGIEMASMEMANSYGHSLPGAPGSGYVNPAYVGESGPVHAYGNP 337
                 P+G       +  S G S PG  G+    P + G  G     G P
Sbjct: 366 GARG--PQG-PSGPPGVPGSPGSSRPGLRGA----PGWPGLKGSKGERGRP 409


>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
            sapiens]
          Length = 1751

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 76/326 (23%), Positives = 108/326 (33%), Gaps = 42/326 (12%)

Query: 34   GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSA 93
            G P  PGP      PG      S+     P + GS   P    +      +G    A   
Sbjct: 950  GLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAG----APGP 1005

Query: 94   ASRTSPDHPTSLPEP------DYSEFQSHPYHRASSRQPDYP-GSQRNPDFAGSSSSGNY 146
            A    P  P   P P      D  E    P+  +++R  D P G    P   G       
Sbjct: 1006 AGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFW-STARSADGPQGPPGLPGLKGDPGVPGL 1064

Query: 147  AGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPD 206
             G++      G   P +PG        GP+      GSR        + +P  D +G+P 
Sbjct: 1065 PGAKGEVGADG--VPGFPGLPGREGIAGPQGPKGDRGSRGE------KGDPGKDGVGQPG 1116

Query: 207  YPGADIQPNSPPFFGEPDYPSAEDNQ--NLPSTWREPDYSDAENGHDYGSSETPKMTRGV 264
             PG    P  PP  G   Y S +D    ++P     P ++       +     PK   G 
Sbjct: 1117 LPG----PPGPP--GPVVYVSEQDGSVLSVPGPEGRPGFA------GFPGPAGPKGNLG- 1163

Query: 265  LSRTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLPGAPGSGYVNPAY 324
             S+     P  +    +P GS++     P+G  +   +          G PG  Y  P Y
Sbjct: 1164 -SKGERGSPGPKGEKGEP-GSIFS----PDGGALGPAQKGAKGEPGFRGPPGP-YGRPGY 1216

Query: 325  VGESGPVHAYGNPPLSECDWHKSPQG 350
             GE G     G P ++     K   G
Sbjct: 1217 KGEIGFPGRPGRPGMNGLKGEKGEPG 1242



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 40/170 (23%), Positives = 50/170 (29%), Gaps = 15/170 (8%)

Query: 17   PDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPR 76
            PD        +G     G+   PGP   P Y G    P       RP   G   E   P 
Sbjct: 1186 PDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFP---GRPGRPGMNGLKGEKGEP- 1241

Query: 77   SLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSR--QPDYPGSQRN 134
                    G  S  +       P  P   P P  +          SSR   P  PG+Q  
Sbjct: 1242 --------GDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGP 1293

Query: 135  PDFAGSSSS-GNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPG 183
            P   G+    G        P  F  LE +  G + +    G +     PG
Sbjct: 1294 PGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPG 1343



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 52/200 (26%), Positives = 63/200 (31%), Gaps = 46/200 (23%)

Query: 33   QGYPDVPGPLNNPDYPGT---RSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSN 89
            +G P  PGP   P  PGT    SN ++ +SR  P        P  P +   P   G    
Sbjct: 1251 RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGP--------PGLPGNQGPPGPKG---- 1298

Query: 90   AYSAASRTSPDHPTSLPEPDY----SEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSG- 144
               A     P  P      D+    +E +     R  + Q    G      F GSS  G 
Sbjct: 1299 ---AKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGP 1355

Query: 145  -NYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLG 203
                G R +P   G      P  +S    PGP      PG              Y    G
Sbjct: 1356 PGPPGPRGYPGIPG------PKGESIRGQPGPPGPQGPPGI------------GYEGRQG 1397

Query: 204  KPDYPGADIQPNSPPFFGEP 223
             P  PG    P  PP F  P
Sbjct: 1398 PPGPPG----PPGPPSFPGP 1413



 Score = 30.8 bits (68), Expect = 6.7
 Identities = 18/51 (35%), Positives = 21/51 (41%), Gaps = 5/51 (9%)

Query: 28   GYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSL 78
            GY   QG P  PGP   P +PG      SV     P  PG    P  P ++
Sbjct: 1391 GYEGRQGPPGPPGPPGPPSFPGPHRQTISV-----PGPPGPPGPPGPPGTM 1436


>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1336

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 76/326 (23%), Positives = 108/326 (33%), Gaps = 42/326 (12%)

Query: 34  GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSA 93
           G P  PGP      PG      S+     P + GS   P    +      +G    A   
Sbjct: 535 GLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAG----APGP 590

Query: 94  ASRTSPDHPTSLPEP------DYSEFQSHPYHRASSRQPDYP-GSQRNPDFAGSSSSGNY 146
           A    P  P   P P      D  E    P+  +++R  D P G    P   G       
Sbjct: 591 AGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFW-STARSADGPQGPPGLPGLKGDPGVPGL 649

Query: 147 AGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPD 206
            G++      G   P +PG        GP+      GSR        + +P  D +G+P 
Sbjct: 650 PGAKGEVGADG--VPGFPGLPGREGIAGPQGPKGDRGSRGE------KGDPGKDGVGQPG 701

Query: 207 YPGADIQPNSPPFFGEPDYPSAEDNQ--NLPSTWREPDYSDAENGHDYGSSETPKMTRGV 264
            PG    P  PP  G   Y S +D    ++P     P ++       +     PK   G 
Sbjct: 702 LPG----PPGPP--GPVVYVSEQDGSVLSVPGPEGRPGFA------GFPGPAGPKGNLG- 748

Query: 265 LSRTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLPGAPGSGYVNPAY 324
            S+     P  +    +P GS++     P+G  +   +          G PG  Y  P Y
Sbjct: 749 -SKGERGSPGPKGEKGEP-GSIFS----PDGGALGPAQKGAKGEPGFRGPPGP-YGRPGY 801

Query: 325 VGESGPVHAYGNPPLSECDWHKSPQG 350
            GE G     G P ++     K   G
Sbjct: 802 KGEIGFPGRPGRPGMNGLKGEKGEPG 827



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 40/170 (23%), Positives = 50/170 (29%), Gaps = 15/170 (8%)

Query: 17  PDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPR 76
           PD        +G     G+   PGP   P Y G    P       RP   G   E   P 
Sbjct: 771 PDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFP---GRPGRPGMNGLKGEKGEP- 826

Query: 77  SLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSR--QPDYPGSQRN 134
                   G  S  +       P  P   P P  +          SSR   P  PG+Q  
Sbjct: 827 --------GDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGP 878

Query: 135 PDFAGSSSS-GNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPG 183
           P   G+    G        P  F  LE +  G + +    G +     PG
Sbjct: 879 PGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPG 928



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 52/200 (26%), Positives = 63/200 (31%), Gaps = 46/200 (23%)

Query: 33  QGYPDVPGPLNNPDYPGT---RSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSN 89
           +G P  PGP   P  PGT    SN ++ +SR  P        P  P +   P   G    
Sbjct: 836 RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGP--------PGLPGNQGPPGPKG---- 883

Query: 90  AYSAASRTSPDHPTSLPEPDY----SEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSG- 144
              A     P  P      D+    +E +     R  + Q    G      F GSS  G 
Sbjct: 884 ---AKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGP 940

Query: 145 -NYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLG 203
               G R +P   G      P  +S    PGP      PG              Y    G
Sbjct: 941 PGPPGPRGYPGIPG------PKGESIRGQPGPPGPQGPPGI------------GYEGRQG 982

Query: 204 KPDYPGADIQPNSPPFFGEP 223
            P  PG    P  PP F  P
Sbjct: 983 PPGPPG----PPGPPSFPGP 998



 Score = 30.8 bits (68), Expect = 6.7
 Identities = 18/51 (35%), Positives = 21/51 (41%), Gaps = 5/51 (9%)

Query: 28   GYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSL 78
            GY   QG P  PGP   P +PG      SV     P  PG    P  P ++
Sbjct: 976  GYEGRQGPPGPPGPPGPPSFPGPHRQTISV-----PGPPGPPGPPGPPGTM 1021


>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1516

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 76/326 (23%), Positives = 108/326 (33%), Gaps = 42/326 (12%)

Query: 34   GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSA 93
            G P  PGP      PG      S+     P + GS   P    +      +G    A   
Sbjct: 715  GLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAG----APGP 770

Query: 94   ASRTSPDHPTSLPEP------DYSEFQSHPYHRASSRQPDYP-GSQRNPDFAGSSSSGNY 146
            A    P  P   P P      D  E    P+  +++R  D P G    P   G       
Sbjct: 771  AGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFW-STARSADGPQGPPGLPGLKGDPGVPGL 829

Query: 147  AGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPD 206
             G++      G   P +PG        GP+      GSR        + +P  D +G+P 
Sbjct: 830  PGAKGEVGADG--VPGFPGLPGREGIAGPQGPKGDRGSRGE------KGDPGKDGVGQPG 881

Query: 207  YPGADIQPNSPPFFGEPDYPSAEDNQ--NLPSTWREPDYSDAENGHDYGSSETPKMTRGV 264
             PG    P  PP  G   Y S +D    ++P     P ++       +     PK   G 
Sbjct: 882  LPG----PPGPP--GPVVYVSEQDGSVLSVPGPEGRPGFA------GFPGPAGPKGNLG- 928

Query: 265  LSRTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLPGAPGSGYVNPAY 324
             S+     P  +    +P GS++     P+G  +   +          G PG  Y  P Y
Sbjct: 929  -SKGERGSPGPKGEKGEP-GSIFS----PDGGALGPAQKGAKGEPGFRGPPGP-YGRPGY 981

Query: 325  VGESGPVHAYGNPPLSECDWHKSPQG 350
             GE G     G P ++     K   G
Sbjct: 982  KGEIGFPGRPGRPGMNGLKGEKGEPG 1007



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 40/170 (23%), Positives = 50/170 (29%), Gaps = 15/170 (8%)

Query: 17   PDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPR 76
            PD        +G     G+   PGP   P Y G    P       RP   G   E   P 
Sbjct: 951  PDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFP---GRPGRPGMNGLKGEKGEP- 1006

Query: 77   SLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSR--QPDYPGSQRN 134
                    G  S  +       P  P   P P  +          SSR   P  PG+Q  
Sbjct: 1007 --------GDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGP 1058

Query: 135  PDFAGSSSS-GNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPG 183
            P   G+    G        P  F  LE +  G + +    G +     PG
Sbjct: 1059 PGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPG 1108



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 52/200 (26%), Positives = 63/200 (31%), Gaps = 46/200 (23%)

Query: 33   QGYPDVPGPLNNPDYPGT---RSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSN 89
            +G P  PGP   P  PGT    SN ++ +SR  P        P  P +   P   G    
Sbjct: 1016 RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGP--------PGLPGNQGPPGPKG---- 1063

Query: 90   AYSAASRTSPDHPTSLPEPDY----SEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSG- 144
               A     P  P      D+    +E +     R  + Q    G      F GSS  G 
Sbjct: 1064 ---AKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGP 1120

Query: 145  -NYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLG 203
                G R +P   G      P  +S    PGP      PG              Y    G
Sbjct: 1121 PGPPGPRGYPGIPG------PKGESIRGQPGPPGPQGPPGI------------GYEGRQG 1162

Query: 204  KPDYPGADIQPNSPPFFGEP 223
             P  PG    P  PP F  P
Sbjct: 1163 PPGPPG----PPGPPSFPGP 1178



 Score = 30.8 bits (68), Expect = 6.7
 Identities = 18/51 (35%), Positives = 21/51 (41%), Gaps = 5/51 (9%)

Query: 28   GYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSL 78
            GY   QG P  PGP   P +PG      SV     P  PG    P  P ++
Sbjct: 1156 GYEGRQGPPGPPGPPGPPSFPGPHRQTISV-----PGPPGPPGPPGPPGTM 1201


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 45/190 (23%), Positives = 66/190 (34%), Gaps = 33/190 (17%)

Query: 14   PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSN---PYSVASRTRPDYPGSLA 70
            P  P + GS+    G + T G P  PGP+  P  PG + +   P S   R  P   G   
Sbjct: 869  PGIPGFPGSKGE-MGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKG 927

Query: 71   E---PNYPRSLSNPDYSGTRSN------------AYSAASRTSPDHPTSLPEPDYSEFQS 115
            +   P  P S+   D    +                   SR  P  P  +P  D      
Sbjct: 928  DVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTP-GVPGKD------ 980

Query: 116  HPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGP 175
                   + QP  PG + +P  +G+  +    G +      G   P  PG +     PGP
Sbjct: 981  -----GQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGL--PGTPGEKGVPGIPGP 1033

Query: 176  RANLNHPGSR 185
            + +   PG +
Sbjct: 1034 QGSPGLPGDK 1043



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 71/327 (21%), Positives = 99/327 (30%), Gaps = 27/327 (8%)

Query: 34   GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSA 93
            G P +PG       PG + +P SV     P  PG   +   P     P   G  +     
Sbjct: 1088 GIPGMPGS------PGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKG-EAGLPGT 1140

Query: 94   ASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHP 153
               T P      P  D       P       +P  PG +  P F G+       G    P
Sbjct: 1141 PGPTGPAGQKGEPGSD-----GIPGSAGEKGEPGLPG-RGFPGFPGAKGDKGSKGEVGFP 1194

Query: 154  DHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYPGADIQ 213
               GS  P  PG++      GP      PG   +  H +          G+P  PG    
Sbjct: 1195 GLAGS--PGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLP-G 1251

Query: 214  PNSPPFFGEPDYPSAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGVLSRTSSIQP 273
            P  PP  G P     + ++  P     P     +    +        + G+      + P
Sbjct: 1252 PMGPP--GLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGP 1309

Query: 274  SFRHRSDDPVGSLWGENDYP--EGIEMASMEMANSYGHSLPGAPGSGYVNPAYVGESGPV 331
                     V    G    P  +GI+    +        LPG PG         GE G  
Sbjct: 1310 P-------GVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLP 1362

Query: 332  HAYGNPPLSECDWHKSPQGQKLIASLI 358
               G P L        P+GQ+ +  L+
Sbjct: 1363 GPEGPPGLKGLQGLPGPKGQQGVTGLV 1389



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 45/195 (23%), Positives = 56/195 (28%), Gaps = 12/195 (6%)

Query: 33  QGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYS 92
           QG P V G    P  PG R  P     +     PG   EP YP  +      G +  A  
Sbjct: 269 QGMPGV-GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGP 327

Query: 93  AASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNP-----DFAGSSSSGNYA 147
                       L E     +   P  R       +PG    P        G + +  + 
Sbjct: 328 PGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFP 387

Query: 148 GSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDY 207
           G R      G      PG       PGP  +   PG +    +      P     G P  
Sbjct: 388 GERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPG-QPGYTNGIVECQP-----GPPGD 441

Query: 208 PGADIQPNSPPFFGE 222
            G    P  P F GE
Sbjct: 442 QGPPGIPGQPGFIGE 456



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 53/232 (22%), Positives = 70/232 (30%), Gaps = 22/232 (9%)

Query: 13  DPDYPDYSGSQNR--TQGYLKTQGYPDVPGPLNNPDYPG------TRSNPYSVASRTRPD 64
           +P  P   G++      GY    G P +PG    P  PG      T+     +     P 
Sbjct: 83  EPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPG 142

Query: 65  YPGSLAEPNYPRSLSNP-DYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASS 123
           + G+   P  P    +P +  G          R  P  P +   P     Q        +
Sbjct: 143 FAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFT 202

Query: 124 RQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPG 183
             P  PG    P   G              D   S  P  PG Q+     G  A     G
Sbjct: 203 GPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPG-QAQVQEKGDFATKGEKG 261

Query: 184 SRKNLEHTSFRINPYADSLGKPDYPGADIQPN---------SPPFFGEPDYP 226
            +       F+  P     G+P  PG   +P          SP F GEP YP
Sbjct: 262 QKGE---PGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYP 310



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 91/392 (23%), Positives = 115/392 (29%), Gaps = 76/392 (19%)

Query: 11  EEDPDYPDYSGSQNRTQGYLKTQGYPDVPGPLNN---PDYPGTRSNPYSVASRTRPDYPG 67
           ++ P  P      N T+G     G P +PG   N   P  PG + +P  +        PG
Sbjct: 113 QDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHV----PG 168

Query: 68  SLAE-----PNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQ-------- 114
            L +     P  P +   P   G +         T P  P   P P   + Q        
Sbjct: 169 MLLKGERGFPGIPGTPGPPGLPGLQ-GPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGP 227

Query: 115 -SHPYHRASSRQPDYPGS---QRNPDFAGSSSSGNYA-------------------GSRT 151
                 +  S  P  PG    Q   DFA     G                      G R 
Sbjct: 228 KGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRG 287

Query: 152 HPDHFGSL----------EPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADS 201
            P   G            EP YPG        G +     PG    +  T     P  + 
Sbjct: 288 KPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGT----GPLGEK 343

Query: 202 LGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMT 261
            G+  YPG       P   G P  P       LP     P  + A     +      K  
Sbjct: 344 -GERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLP----VPGQAGAPG---FPGERGEKGD 395

Query: 262 RGVLSRTSSIQPSFRHRSDDPVGSLW--GENDYPEGIEMASMEMANSYGHSLPGAPGSGY 319
           RG    TS   PS R     P GS    G+  Y  GI           G   PG PG   
Sbjct: 396 RG-FPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGP--PGIPG--- 449

Query: 320 VNPAYVGESGPVHAYGNPPL-SECDWHKSPQG 350
             P ++GE G     G   L  + D ++ P G
Sbjct: 450 -QPGFIGEIGEKGQKGESCLICDIDGYRGPPG 480



 Score = 35.4 bits (80), Expect = 0.27
 Identities = 69/321 (21%), Positives = 98/321 (30%), Gaps = 45/321 (14%)

Query: 34  GYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEP---NYPRSLSNPDYSGTRSNA 90
           GY   PGP   P   G    P +   R  P   G    P     P  +  P   G     
Sbjct: 474 GYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEF 533

Query: 91  YSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSR 150
           Y              P          P     +  P   G    P   GS  S    G R
Sbjct: 534 YFDLRLKGDKGDPGFP--------GQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGER 585

Query: 151 THPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSL-GKPDYPG 209
             P   G     +PG++ ++  PGP       G   +     F   P +  L G    PG
Sbjct: 586 GPPGGVG-----FPGSRGDTGPPGP-PGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPG 639

Query: 210 ADIQPNSPP----FFGEPDYPSAEDNQNLPSTWREPDY-----SDAENGHDYGSSETPKM 260
             +    PP      G P +P  + ++  P T   P       +  + G  +     PK 
Sbjct: 640 KIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKG 699

Query: 261 TRGVLSRT----SSIQPSFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLPGAPG 316
             G+        +  +P F     +P   + G+   P G+ +  ++        LPG PG
Sbjct: 700 VDGLPGDMGPPGTPGRPGFNGLPGNP--GVQGQKGEP-GVGLPGLK-------GLPGLPG 749

Query: 317 SGYVNPAYVGESGPVHAYGNP 337
                P   GE G +   G P
Sbjct: 750 I----PGTPGEKGSIGVPGVP 766



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 40/180 (22%), Positives = 52/180 (28%), Gaps = 19/180 (10%)

Query: 13  DPDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEP 72
           DP +P   G   R             PG   +P  PG + +P SV  +     PG +  P
Sbjct: 545 DPGFPGQPGMTGRAGS----------PGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFP 594

Query: 73  NY--------PRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEP-DYSEFQSHPYHRASS 123
                     P         G +  A       SP  P    EP         P      
Sbjct: 595 GSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLP 654

Query: 124 RQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPG 183
             P +PG Q +  F G+       G +      G   P  PG +     PG       PG
Sbjct: 655 GSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPG 714



 Score = 31.2 bits (69), Expect = 5.1
 Identities = 49/216 (22%), Positives = 66/216 (30%), Gaps = 24/216 (11%)

Query: 25  RTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYS 84
           R +G     G+P  PG       PG   +P     +  P   G   E   P  +  P   
Sbjct: 538 RLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFP--- 594

Query: 85  GTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSG 144
           G+R +       T P  P     P Y    + P       Q  +PG   +P   G     
Sbjct: 595 GSRGD-------TGPPGP-----PGYG--PAGPI--GDKGQAGFPGGPGSPGLPGPKGEP 638

Query: 145 NYAGSRTHPDHFGSL--EPDYPGAQSNSDHPGPRANLNHPGSRKNLEH--TSFRINPYAD 200
                   P     L   P +PG Q +   PG       PG +  +      F   P   
Sbjct: 639 GKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPK 698

Query: 201 SL-GKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLP 235
            + G P   G    P  P F G P  P  +  +  P
Sbjct: 699 GVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEP 734


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 43/193 (22%), Positives = 62/193 (32%), Gaps = 19/193 (9%)

Query: 20  SGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLS 79
           S  +N   G +  +G P   G    P   G R N  +  +   P   G    P +P    
Sbjct: 291 SPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFP---- 346

Query: 80  NPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQP-DYPGSQRNPDFA 138
                     A  A     P  P     P     +  P   A +  P   PG+   P   
Sbjct: 347 ---------GAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAK 397

Query: 139 GSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPY 198
           G++ +   AG+   P   G   P  PG       PGP+ N   PG+  +   T  +  P 
Sbjct: 398 GANGAPGIAGAPGFPGARGPSGPQGPGGP-----PGPKGNSGEPGAPGSKGDTGAKGEPG 452

Query: 199 ADSLGKPDYPGAD 211
              +  P  P  +
Sbjct: 453 PVGVQGPPGPAGE 465



 Score = 38.1 bits (87), Expect = 0.042
 Identities = 45/195 (23%), Positives = 63/195 (32%), Gaps = 19/195 (9%)

Query: 40  GPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSP 99
           G    P  PG R  P    +R     PG+   P            G + +A  A  +  P
Sbjct: 233 GEAGKPGRPGERGPPGPQGAR---GLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEP 289

Query: 100 DHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSL 159
             P     P     +  P  R     P   G++ N    G++      G    P   G++
Sbjct: 290 GSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAV 349

Query: 160 EPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYPGADIQP----- 214
                GA+  +   GPR +    G R             A + G    PGAD QP     
Sbjct: 350 -----GAKGEAGPQGPRGSEGPQGVRGEPGPPG-----PAGAAGPAGNPGADGQPGAKGA 399

Query: 215 -NSPPFFGEPDYPSA 228
             +P   G P +P A
Sbjct: 400 NGAPGIAGAPGFPGA 414



 Score = 36.2 bits (82), Expect = 0.16
 Identities = 52/233 (22%), Positives = 72/233 (30%), Gaps = 19/233 (8%)

Query: 12  EDPDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPD---------YPGTRSNPYSVASRTR 62
           + P  P     +   QG   + G+  +PGP   P           PG    P    +R  
Sbjct: 619 QGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGE 678

Query: 63  PDYPGSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRAS 122
             +PG       P        +G   N  +     +P  P S   P     Q  P  R +
Sbjct: 679 RGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPG---LQGMPGERGA 735

Query: 123 SRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHP 182
           +  P   G + +    G+  S    G R      G   P   GA  +    GP       
Sbjct: 736 AGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIG--PPGPAGAPGDKGESGPSGPAGPT 793

Query: 183 GSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLP 235
           G+R           P       P  PGAD QP +    GEP    A+ +   P
Sbjct: 794 GARGAPGDRGEPGPPGPAGFAGP--PGADGQPGAK---GEPGDAGAKGDAGPP 841



 Score = 34.3 bits (77), Expect = 0.61
 Identities = 53/249 (21%), Positives = 76/249 (30%), Gaps = 23/249 (9%)

Query: 7   NNWSEEDPDYPDYSGSQNRT--QGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPD 64
           N+ ++ D   P   GSQ     QG    +G   +PGP  +    G +    S        
Sbjct: 705 NDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRG 764

Query: 65  YPGSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSR 124
             G +  P    +  +   SG    A    +R +P        P  + F   P    +  
Sbjct: 765 LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPP---GADG 821

Query: 125 QPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSL----------------EPDYPGAQS 168
           QP   G   +    G +     AG    P   G++                   +PGA  
Sbjct: 822 QPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAG 881

Query: 169 NSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSA 228
               PGP  N   PG          +  P  ++ G    PG    P  P   GE   P A
Sbjct: 882 RVGPPGPSGNAGPPGPPGPAGKEGGK-GPRGET-GPAGRPGEVGPPGPPGPAGEKGSPGA 939

Query: 229 EDNQNLPST 237
           +     P T
Sbjct: 940 DGPAGAPGT 948



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 60/244 (24%), Positives = 76/244 (31%), Gaps = 47/244 (19%)

Query: 33   QGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYS 92
            +G P   G       PG + +         P  PG+   P  P  +     SG R     
Sbjct: 1015 EGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGA---PGAPGPVGPAGKSGDRGET-G 1070

Query: 93   AASRTSPDHPTSL--------PEPDYSEFQSH-----PYHRASSRQPDYPGSQRNPDFAG 139
             A    P  P           P  D  E           HR  S     PG   +P   G
Sbjct: 1071 PAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQG 1130

Query: 140  SSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYA 199
             S +   AG R  P   G+     PG    +  PGP   +  PG R             A
Sbjct: 1131 PSGASGPAGPRGPPGSAGA-----PGKDGLNGLPGP---IGPPGPRGRTGD--------A 1174

Query: 200  DSLGKPDYPGADIQPNSPPFFGEPDYPSAE-DNQNLPSTWREPDYSDAENGHDYGSSETP 258
              +G P  PG       PP  G P  PSA  D   LP    +P    A +G  Y  ++  
Sbjct: 1175 GPVGPPGPPG-------PP--GPPGPPSAGFDFSFLP----QPPQEKAHDGGRYYRADDA 1221

Query: 259  KMTR 262
             + R
Sbjct: 1222 NVVR 1225



 Score = 30.8 bits (68), Expect = 6.7
 Identities = 44/183 (24%), Positives = 56/183 (30%), Gaps = 39/183 (21%)

Query: 24  NRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNY-----PRSL 78
           N   G     G+P   GP + P  PG    P   +    P  PGS  +        P  +
Sbjct: 400 NGAPGIAGAPGFPGARGP-SGPQGPGGPPGPKGNSGE--PGAPGSKGDTGAKGEPGPVGV 456

Query: 79  SNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQ-----R 133
             P   G         +R  P  PT LP P        P  R       +PG+      +
Sbjct: 457 QGPP--GPAGEEGKRGARGEPG-PTGLPGP--------PGERGGPGSRGFPGADGVAGPK 505

Query: 134 NPDFAGSSSSGNYAGSRTHPDHFG-------------SLEPDYPGAQSNSDHPGPRANLN 180
            P  AG   S   AG +  P   G             +  P  PG    +  PGP     
Sbjct: 506 GP--AGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDG 563

Query: 181 HPG 183
            PG
Sbjct: 564 RPG 566



 Score = 30.8 bits (68), Expect = 6.7
 Identities = 42/194 (21%), Positives = 60/194 (30%), Gaps = 26/194 (13%)

Query: 17  PDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGS-------- 68
           P  SG++   +G+   +G    PGP       G   N  +      P  PGS        
Sbjct: 670 PGPSGARGE-RGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQG 728

Query: 69  ---------LAEPNYPRSLSNP---DYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSH 116
                    L  P   R  + P   D S  +           P  P   P        S 
Sbjct: 729 MPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSG 788

Query: 117 PYHRASSR----QPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSL-EPDYPGAQSNSD 171
           P     +R        PG      FAG   +    G++  P   G+  +   PG    + 
Sbjct: 789 PAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAG 848

Query: 172 HPGPRANLNHPGSR 185
            PGP  N+  PG++
Sbjct: 849 PPGPIGNVGAPGAK 862


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 75/321 (23%), Positives = 96/321 (29%), Gaps = 48/321 (14%)

Query: 33  QGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLA---EPNYPRSLSNPDYSGTRSN 89
           QG P  PGP      PG +  P        P   G L    E   P     P  +G    
Sbjct: 677 QGLPGPPGPPGEGGKPGDQGVPGD------PGAVGPLGPRGERGNPGERGEPGITGLPGE 730

Query: 90  AYSAASRTSPDHPTSLPEPDYSE-------FQSHPYHRASSRQPDYPGSQRNPDFAGSSS 142
              A     PD P   P P  +         Q  P  R  +  P   G +      G+  
Sbjct: 731 KGMAGGH-GPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEG 789

Query: 143 SGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNL----EHTSFRINPY 198
           +    G+R  P   G   P   G       PGPR  +  PGSR N     E+       +
Sbjct: 790 TAGNDGARGLPGPLGP--PGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGF 847

Query: 199 ADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLPSTWREPDYSDAENGHDYGSSETP 258
           A   G    PG   +P  P   G+   P  +     P           + G     ++ P
Sbjct: 848 AGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGR---GTQGP 904

Query: 259 KMTRGVLSRTSSIQPSFRHRSDDPVGSLWGE--NDYPEGIEMASMEMANSYGHSLPGAPG 316
               G       + P     +  P G L GE   + P G               L G PG
Sbjct: 905 PGATGFPGSAGRVGPPGPAGAPGPAGPL-GEPGKEGPPG---------------LRGDPG 948

Query: 317 SGYVNPAYVGESGPVHAYGNP 337
           S       VG+ GP    G P
Sbjct: 949 S----HGRVGDRGPAGPPGGP 965



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 74/323 (22%), Positives = 95/323 (29%), Gaps = 40/323 (12%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPN 73
           P  P   G++  T G    QG     GPL  P   G    P S+  R +P   GS+  P 
Sbjct: 563 PGEPGLPGARGLT-GNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQP---GSMGLPG 618

Query: 74  YPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQR 133
              S  +P   G   NA     R +P     +              R     P   G Q 
Sbjct: 619 PKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQG 678

Query: 134 NPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSF 193
            P   G    G   G +  P   G++ P            GPR    +PG R        
Sbjct: 679 LPGPPGPPGEGGKPGDQGVPGDPGAVGP-----------LGPRGERGNPGER-------- 719

Query: 194 RINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDN-QNLPSTWREPDYSDAENGHDY 252
                    G+P   G   +       G PD P         P     P           
Sbjct: 720 ---------GEPGITGLPGEKGMAGGHG-PDGPKGSPGPSGTPGDTGPPGLQGMPGERGI 769

Query: 253 GSSETPKMTRGVLSRTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLP 312
             +  PK  RG +    +   +    +    G L      P G    + E        L 
Sbjct: 770 AGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLG-----PPGPAGPTGEKGEPGPRGLV 824

Query: 313 GAPGSGYVNPAYVGESGPVHAYG 335
           G PGS   NP   GE+GP  A G
Sbjct: 825 GPPGS-RGNPGSRGENGPTGAVG 846



 Score = 38.5 bits (88), Expect = 0.032
 Identities = 82/332 (24%), Positives = 99/332 (29%), Gaps = 25/332 (7%)

Query: 33  QGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYS 92
           QG     GP   P  PG       + SR     PG   E   P    NP   G    A S
Sbjct: 227 QGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNP---GEVGFAGS 283

Query: 93  AASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTH 152
             +R  P  P     P     + H        +   PGS+      G   +    G R  
Sbjct: 284 PGARGFPGAPGL---PGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGM 340

Query: 153 PDHFGSL----EPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYP 208
           P   G L     P   GA      PGP   L  PGS     +   +          P+ P
Sbjct: 341 PGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGP 400

Query: 209 GADIQPNSPPF-FGEPDYPSAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGVLSR 267
                   PP   G P  P A      P   + P  S   +G   GS+  P    G    
Sbjct: 401 QGQRGETGPPGPVGSPGLPGAIGTDGTPGA-KGPTGSPGTSGPP-GSAGPP----GSPGP 454

Query: 268 TSSIQP-SFRHRSDDP-VGSLWGE-----NDYPEGIEMASMEMANSYGHSLPGAPGSGYV 320
             S  P   R +  DP V    GE        P GI+               G PG+   
Sbjct: 455 QGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGT-VG 513

Query: 321 NPAYVGESGPVHAYGNPPLSECDWHKSPQGQK 352
            P  VGE G     G P        K  QG++
Sbjct: 514 PPGPVGERGAPGNRGFPGSDGLPGPKGAQGER 545



 Score = 35.4 bits (80), Expect = 0.27
 Identities = 77/340 (22%), Positives = 107/340 (31%), Gaps = 69/340 (20%)

Query: 34  GYPDVPGPLNNPDYPGT--RSNPYSVASRTRPD----------YPGSLAE--PNYPRSLS 79
           G P  PGP  +P +PG    S P+S       +           PGS+    P  P+ L 
Sbjct: 168 GQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGL- 226

Query: 80  NPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAG 139
                G +  A        P  P  +        +  P       +P   G+     FAG
Sbjct: 227 ----QGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAG 282

Query: 140 SSSSGNYAGS------RTHPDHFGSLEP----DYPGAQSNSDHPGPRANLNHPGSRKNLE 189
           S  +  + G+      + H  H G   P      PG++  +   GP   +   G R  + 
Sbjct: 283 SPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPR-GMP 341

Query: 190 HTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAE--------DNQNLPSTWREP 241
               R+ P     G P   GA   P  P   G    P +           +  P+  R P
Sbjct: 342 GERGRLGPQ----GAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGP 397

Query: 242 DYSDAENGH-----DYGSSETPKM-----TRGVLSRTSSIQPSFRHRSDDPVGSLWGEND 291
           +    + G        GS   P       T G    T S   S    S  P GS   +  
Sbjct: 398 EGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGS 457

Query: 292 Y-PEGIEMASMEMANSYGHSLPGAPGSGYVNPAYVGESGP 330
             P+GI               PG PG     P + GE+GP
Sbjct: 458 TGPQGI------------RGQPGDPGV----PGFKGEAGP 481



 Score = 30.8 bits (68), Expect = 6.7
 Identities = 44/186 (23%), Positives = 59/186 (31%), Gaps = 24/186 (12%)

Query: 21  GSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPG--SLAEPNYPRSL 78
           GSQ   +G    +G P   GP      PG    P +      P +PG   L+ P   +  
Sbjct: 138 GSQG-PRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMA 196

Query: 79  SNPDYSGTRSNAYSAASRTSP---------------DHPTSLP-EPDYSEFQSHPYHRAS 122
              + SG  S          P                 PT  P EP           R  
Sbjct: 197 GLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGP 256

Query: 123 SRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDH---PGPRANL 179
              P  PG    P   G+     +AGS       G+  P  PG + +  H    GP+  +
Sbjct: 257 EGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGA--PGLPGLKGHRGHKGLEGPKGEV 314

Query: 180 NHPGSR 185
             PGS+
Sbjct: 315 GAPGSK 320



 Score = 30.4 bits (67), Expect = 8.7
 Identities = 35/144 (24%), Positives = 45/144 (31%), Gaps = 23/144 (15%)

Query: 33   QGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYS 92
            +G P +PGP   P   G    P        P  PG +  P     +  P   G   N   
Sbjct: 1004 RGMPGLPGPAGTPGKVG----PTGATGDKGP--PGPVGPPGSNGPVGEPGPEGPAGND-- 1055

Query: 93   AASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTH 152
                 +P    ++ E            R        PGSQ  P   G   +   AG R  
Sbjct: 1056 ----GTPGRDGAVGERG---------DRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGD 1102

Query: 153  PDHFGSLEPDYPGAQSNSDHPGPR 176
            P   G + P  PG       PGP+
Sbjct: 1103 PGSRGPIGP--PGRAGKRGLPGPQ 1124


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 80/363 (22%), Positives = 123/363 (33%), Gaps = 63/363 (17%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPD----YPGTRSNPYSVASRTRPDYP--- 66
           P  P     + R Q Y  T  Y    GP + P     YPG    PY   S+T   YP   
Sbjct: 380 PSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPG---QPYG--SQTPQRYPMTM 434

Query: 67  -----GSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSE--FQSHPYH 119
                 ++   +Y + +  P Y     + Y    +T P +    P P   +  +   P  
Sbjct: 435 QGRAQSAMGGLSYTQQI--PPYGQQGPSGYGQQGQT-PYYNQQSPHPQQQQPPYSQQPPS 491

Query: 120 RASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANL 179
           +    QP Y    ++      SS   Y+   + P H  S  P YP  QS +         
Sbjct: 492 QTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAP-YPSQQSTTQ-------- 542

Query: 180 NHPGSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFG-EPDYPSAEDNQNLPSTW 238
            HP S+           PY+    +  Y     Q  +P     +  YP  +  Q+  + +
Sbjct: 543 QHPQSQP----------PYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAY 592

Query: 239 RE----PDYSDAENGHDYGSSETPKMTR----------GVLSRTSSIQPSFRHRSDDPVG 284
            +    P    +++     +S  P MT            + SR SS+        D P+G
Sbjct: 593 SQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMG 652

Query: 285 S--LWGENDYPEGIEMASMEMANS-----YGHSLPGAPGSGYVNPAYVGESGPVHAYGNP 337
           +           GI  +  E +N        H+ P  PG    +P+ VG    V    + 
Sbjct: 653 TEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSG 712

Query: 338 PLS 340
           PLS
Sbjct: 713 PLS 715


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 80/363 (22%), Positives = 123/363 (33%), Gaps = 63/363 (17%)

Query: 14  PDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPD----YPGTRSNPYSVASRTRPDYP--- 66
           P  P     + R Q Y  T  Y    GP + P     YPG    PY   S+T   YP   
Sbjct: 380 PSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPG---QPYG--SQTPQRYPMTM 434

Query: 67  -----GSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSE--FQSHPYH 119
                 ++   +Y + +  P Y     + Y    +T P +    P P   +  +   P  
Sbjct: 435 QGRAQSAMGGLSYTQQI--PPYGQQGPSGYGQQGQT-PYYNQQSPHPQQQQPPYSQQPPS 491

Query: 120 RASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANL 179
           +    QP Y    ++      SS   Y+   + P H  S  P YP  QS +         
Sbjct: 492 QTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAP-YPSQQSTTQ-------- 542

Query: 180 NHPGSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFG-EPDYPSAEDNQNLPSTW 238
            HP S+           PY+    +  Y     Q  +P     +  YP  +  Q+  + +
Sbjct: 543 QHPQSQP----------PYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAY 592

Query: 239 RE----PDYSDAENGHDYGSSETPKMTR----------GVLSRTSSIQPSFRHRSDDPVG 284
            +    P    +++     +S  P MT            + SR SS+        D P+G
Sbjct: 593 SQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMG 652

Query: 285 S--LWGENDYPEGIEMASMEMANS-----YGHSLPGAPGSGYVNPAYVGESGPVHAYGNP 337
           +           GI  +  E +N        H+ P  PG    +P+ VG    V    + 
Sbjct: 653 TEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSG 712

Query: 338 PLS 340
           PLS
Sbjct: 713 PLS 715


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,089,732
Number of Sequences: 37866
Number of extensions: 2124981
Number of successful extensions: 9016
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 217
Number of HSP's that attempted gapping in prelim test: 6659
Number of HSP's gapped (non-prelim): 1424
length of query: 1006
length of database: 18,247,518
effective HSP length: 112
effective length of query: 894
effective length of database: 14,006,526
effective search space: 12521834244
effective search space used: 12521834244
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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