Search of human proteins with 157426823

Search of human proteins with 157426823

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157426823 NK2 homeobox 4 [Homo sapiens]
         (354 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157426823 NK2 homeobox 4 [Homo sapiens]                            724   0.0  
gi|118766339 thyroid transcription factor 1 isoform 1 [Homo sapi...   357   9e-99
gi|4507715 thyroid transcription factor 1 isoform 2 [Homo sapiens]    357   9e-99
gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]   144   2e-34
gi|4505401 NK2 transcription factor related, locus 2 [Homo sapiens]   142   5e-34
gi|148746211 NK2 transcription factor related, locus 3 [Homo sap...   142   6e-34
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap...   137   2e-32
gi|31377777 NK2 homeobox 8 [Homo sapiens]                             127   1e-29
gi|4502365 NK3 homeobox 2 [Homo sapiens]                              108   9e-24
gi|116805350 homeo box (H6 family) 1 [Homo sapiens]                    96   6e-20
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]                92   7e-19
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  91   1e-18
gi|89257348 homeo box HB9 [Homo sapiens]                               87   3e-17
gi|169636435 caudal type homeobox 2 [Homo sapiens]                     86   7e-17
gi|19923352 NK3 homeobox 1 [Homo sapiens]                              86   7e-17
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  82   7e-16
gi|84570137 homeobox B3 [Homo sapiens]                                 81   1e-15
gi|4758168 distal-less homeobox 2 [Homo sapiens]                       81   2e-15
gi|111120318 NK6 transcription factor related, locus 1 [Homo sap...    81   2e-15
gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]                   80   2e-15
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]           80   4e-15
gi|157743259 H6 family homeobox 3 [Homo sapiens]                       79   5e-15
gi|23510368 homeobox D11 [Homo sapiens]                                75   7e-14
gi|13375632 homeobox D1 [Homo sapiens]                                 75   7e-14
gi|118582284 msh homeobox 1 [Homo sapiens]                             75   9e-14
gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]                   75   1e-13
gi|4503615 even-skipped homeobox 1 [Homo sapiens]                      74   2e-13
gi|147901462 brain specific homeobox [Homo sapiens]                    74   2e-13
gi|70608170 H6 family homeobox 2 [Homo sapiens]                        73   4e-13
gi|24497515 homeobox A3 isoform b [Homo sapiens]                       72   6e-13

>gi|157426823 NK2 homeobox 4 [Homo sapiens]
          Length = 354

 Score =  724 bits (1870), Expect = 0.0
 Identities = 354/354 (100%), Positives = 354/354 (100%)

Query: 1   MSLSPKHTTPFSVSDILSPIEETYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQAA 60
           MSLSPKHTTPFSVSDILSPIEETYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQAA
Sbjct: 1   MSLSPKHTTPFSVSDILSPIEETYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQAA 60

Query: 61  TVAGMQPSHAMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQFPHGAMGSYCNGGLGNMGE 120
           TVAGMQPSHAMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQFPHGAMGSYCNGGLGNMGE
Sbjct: 61  TVAGMQPSHAMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQFPHGAMGSYCNGGLGNMGE 120

Query: 121 LPAYTDGMRGGAATGWYGANPDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLGPLH 180
           LPAYTDGMRGGAATGWYGANPDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLGPLH
Sbjct: 121 LPAYTDGMRGGAATGWYGANPDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLGPLH 180

Query: 181 AAAAAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNH 240
           AAAAAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNH
Sbjct: 181 AAAAAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNH 240

Query: 241 RYKMKRQAKDKAAQQLQQEGGLGPPPPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAG 300
           RYKMKRQAKDKAAQQLQQEGGLGPPPPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAG
Sbjct: 241 RYKMKRQAKDKAAQQLQQEGGLGPPPPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAG 300

Query: 301 PQPPAPTPAPELEELSPSPPALHGPGGGLAALDAAAGEYSGGVLGANLLYGRTW 354
           PQPPAPTPAPELEELSPSPPALHGPGGGLAALDAAAGEYSGGVLGANLLYGRTW
Sbjct: 301 PQPPAPTPAPELEELSPSPPALHGPGGGLAALDAAAGEYSGGVLGANLLYGRTW 354


>gi|118766339 thyroid transcription factor 1 isoform 1 [Homo
           sapiens]
          Length = 401

 Score =  357 bits (916), Expect = 9e-99
 Identities = 217/404 (53%), Positives = 249/404 (61%), Gaps = 83/404 (20%)

Query: 1   MSLSPKHTTPFSVSDILSPIEETYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQAA 60
           MS+SPKHTTPFSVSDILSP+EE+YKK    M+G   GLGAPL A    +A PP       
Sbjct: 31  MSMSPKHTTPFSVSDILSPLEESYKKVG--MEGG--GLGAPLAAYRQGQAAPP------- 79

Query: 61  TVAGMQPSHAMAGHNAAAAAAAAAAAAAAAATYHMPP-GVSQFPHGAMGSYCNGGLGNMG 119
             A MQ  HA+  H A  AA            YHM   GV Q  H A+G YCNG LGNM 
Sbjct: 80  -TAAMQ-QHAVGHHGAVTAA------------YHMTAAGVPQLSHSAVGGYCNGNLGNMS 125

Query: 120 ELPAYTDGMRGGAA-TGWYGANPDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLGP 178
           ELP Y D MR  A+  GWYGANPDPR+ +ISRFMGP++G+N++GMG L  + D +K++ P
Sbjct: 126 ELPPYQDTMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLGDVSKNMAP 185

Query: 179 LHAAAAAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQ 238
           L      +APRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQ
Sbjct: 186 L-----PSAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQ 240

Query: 239 NHRYKMKRQAKDKAA-QQLQQE-------GGLGPP---PPPPPSPRRVAVPVLVKDGKPC 287
           NHRYKMKRQAKDKAA QQLQQ+       GG G P        SPRRVAVPVLVKDGKPC
Sbjct: 241 NHRYKMKRQAKDKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVLVKDGKPC 300

Query: 288 QNGASTPTPGQA-------------------------------------GPQPPAPTPAP 310
           Q GA  P PG A                                     G QP +   +P
Sbjct: 301 QAGA--PAPGAASLQGHAQQQAQHQAQAAQAAAAAISVGSGGAGLGAHPGHQPGSAGQSP 358

Query: 311 ELEELSPSPPALHGPGGGLAALDAAAGEYSGGVLGANLLYGRTW 354
           +L   + SP AL G    L+ L+++  +Y G +  + LLYGRTW
Sbjct: 359 DLAHHAASPAALQGQVSSLSHLNSSGSDY-GTMSCSTLLYGRTW 401


>gi|4507715 thyroid transcription factor 1 isoform 2 [Homo sapiens]
          Length = 371

 Score =  357 bits (916), Expect = 9e-99
 Identities = 217/404 (53%), Positives = 249/404 (61%), Gaps = 83/404 (20%)

Query: 1   MSLSPKHTTPFSVSDILSPIEETYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQAA 60
           MS+SPKHTTPFSVSDILSP+EE+YKK    M+G   GLGAPL A    +A PP       
Sbjct: 1   MSMSPKHTTPFSVSDILSPLEESYKKVG--MEGG--GLGAPLAAYRQGQAAPP------- 49

Query: 61  TVAGMQPSHAMAGHNAAAAAAAAAAAAAAAATYHMPP-GVSQFPHGAMGSYCNGGLGNMG 119
             A MQ  HA+  H A  AA            YHM   GV Q  H A+G YCNG LGNM 
Sbjct: 50  -TAAMQ-QHAVGHHGAVTAA------------YHMTAAGVPQLSHSAVGGYCNGNLGNMS 95

Query: 120 ELPAYTDGMRGGAA-TGWYGANPDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLGP 178
           ELP Y D MR  A+  GWYGANPDPR+ +ISRFMGP++G+N++GMG L  + D +K++ P
Sbjct: 96  ELPPYQDTMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLGDVSKNMAP 155

Query: 179 LHAAAAAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQ 238
           L      +APRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQ
Sbjct: 156 L-----PSAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQ 210

Query: 239 NHRYKMKRQAKDKAA-QQLQQE-------GGLGPP---PPPPPSPRRVAVPVLVKDGKPC 287
           NHRYKMKRQAKDKAA QQLQQ+       GG G P        SPRRVAVPVLVKDGKPC
Sbjct: 211 NHRYKMKRQAKDKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVLVKDGKPC 270

Query: 288 QNGASTPTPGQA-------------------------------------GPQPPAPTPAP 310
           Q GA  P PG A                                     G QP +   +P
Sbjct: 271 QAGA--PAPGAASLQGHAQQQAQHQAQAAQAAAAAISVGSGGAGLGAHPGHQPGSAGQSP 328

Query: 311 ELEELSPSPPALHGPGGGLAALDAAAGEYSGGVLGANLLYGRTW 354
           +L   + SP AL G    L+ L+++  +Y G +  + LLYGRTW
Sbjct: 329 DLAHHAASPAALQGQVSSLSHLNSSGSDY-GTMSCSTLLYGRTW 371


>gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]
          Length = 324

 Score =  144 bits (362), Expect = 2e-34
 Identities = 73/117 (62%), Positives = 86/117 (73%), Gaps = 6/117 (5%)

Query: 180 HAAAAAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQN 239
           +A    A  RRK RVLFSQAQVYELERRFKQQ+YLSAPER+ LAS++ LT TQVKIWFQN
Sbjct: 129 NAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQN 188

Query: 240 HRYKMKRQAKDKAAQQLQQEGGLGPPPPPPPSPRRVAVPVLVKDGKPCQNGASTPTP 296
            RYK KRQ +D+  +       +G PPPPPP  RR+AVPVLV+DGKPC   ++   P
Sbjct: 189 RRYKCKRQRQDQTLEL------VGLPPPPPPPARRIAVPVLVRDGKPCLGDSAPYAP 239


>gi|4505401 NK2 transcription factor related, locus 2 [Homo sapiens]
          Length = 273

 Score =  142 bits (358), Expect = 5e-34
 Identities = 72/102 (70%), Positives = 79/102 (77%), Gaps = 11/102 (10%)

Query: 186 AAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMK 245
           A  +RKRRVLFS+AQ YELERRF+QQ+YLSAPEREHLAS+I LTPTQVKIWFQNHRYKMK
Sbjct: 125 AGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMK 184

Query: 246 RQAKDKAAQQLQQEGGLGPPPPPPPSPRRVAVPVLVKDGKPC 287
           R   +K           G    P PSPRRVAVPVLV+DGKPC
Sbjct: 185 RARAEK-----------GMEVTPLPSPRRVAVPVLVRDGKPC 215


>gi|148746211 NK2 transcription factor related, locus 3 [Homo
           sapiens]
          Length = 364

 Score =  142 bits (357), Expect = 6e-34
 Identities = 92/167 (55%), Positives = 104/167 (62%), Gaps = 21/167 (12%)

Query: 174 KSLGPLHAAAAAAAP----RRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLT 229
           ++ G   AA  +  P    RRK RVLFSQAQV+ELERRFKQQ+YLSAPEREHLAS + LT
Sbjct: 129 ETAGDCKAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLT 188

Query: 230 PTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGLGPPPPPPPSPRRVAVPVLVKDGKPCQN 289
            TQVKIWFQN RYK KRQ +DK+ +       LG   PPPP PRRVAVPVLV+DGKPC  
Sbjct: 189 STQVKIWFQNRRYKCKRQRQDKSLE-------LGAHAPPPP-PRRVAVPVLVRDGKPC-- 238

Query: 290 GASTPTPGQAGPQPPAPTPAPELEELSPSPPALHGPGGGLAALDAAA 336
              TP+    G    AP           S PA +G G   AA  AAA
Sbjct: 239 --VTPSAQAYG----APYSVGASAYSYNSFPA-YGYGNSAAAAAAAA 278



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 45/138 (32%), Positives = 56/138 (40%), Gaps = 16/138 (11%)

Query: 44  AAAAYRAPPPGPSSQAATVAGMQPSHAMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQFP 103
           +A AY AP     S  A+        A    N+AAAAAAAAAAAAAAA Y    G     
Sbjct: 242 SAQAYGAP----YSVGASAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSSSYGC---- 293

Query: 104 HGAMGSYCNGGLGNMGELPAYTDGMRGGAATGWYGANPDPRYSSISRFMGPSAGVNVAGM 163
                +Y  GG G  G   A T  M+   +    G  P    S++  F G          
Sbjct: 294 -----AYPAGGGGGGGGTSAATTAMQPACSAA--GGGPFVNVSNLGGF-GSGGSAQPLHQ 345

Query: 164 GSLTGIADAAKSLGPLHA 181
           G+  G A A  +L  + A
Sbjct: 346 GTAAGAACAQGTLQGIRA 363



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 36/118 (30%), Positives = 47/118 (39%), Gaps = 29/118 (24%)

Query: 33  GAPPGLGAPLGAAAAYRAPPPGPSSQAATVAGMQPSHAMAGHNAAAAAAAAAAAAA---- 88
           GAP  +GA   +  ++ A   G S+ AA  A            AAAAAAAAA +++    
Sbjct: 247 GAPYSVGASAYSYNSFPAYGYGNSAAAAAAA------------AAAAAAAAAYSSSYGCA 294

Query: 89  ------------AAATYHMPPGVSQFPHGAMGSYCN-GGLGNMGELPAYTDGMRGGAA 133
                       +AAT  M P  S    G   +  N GG G+ G       G   GAA
Sbjct: 295 YPAGGGGGGGGTSAATTAMQPACSAAGGGPFVNVSNLGGFGSGGSAQPLHQGTAAGAA 352



 Score = 28.5 bits (62), Expect = 9.5
 Identities = 14/27 (51%), Positives = 20/27 (74%), Gaps = 1/27 (3%)

Query: 4  SPKHTTPFSVSDILSPIEETYKKFSGA 30
          SP  +TPFSV DIL+ +E+ ++ F GA
Sbjct: 5  SPVTSTPFSVKDILN-LEQQHQHFHGA 30


>gi|210147470 NK2 transcription factor related, locus 6 [Homo
           sapiens]
          Length = 219

 Score =  137 bits (344), Expect = 2e-32
 Identities = 87/171 (50%), Positives = 103/171 (60%), Gaps = 28/171 (16%)

Query: 154 PSAGVNVAG-MGSLT-----GIADAAKSLGPLHAAAAAAAPRRKRRVLFSQAQVYELERR 207
           P  G+N A  +G  T     G+ ++  S+    +    A  RRK RVLFSQAQV  LERR
Sbjct: 9   PQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERR 68

Query: 208 FKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGLGPPPP 267
           FKQQ+YLSAPEREHLAS + LT TQVKIWFQN RYK KRQ +DK+   L+  G       
Sbjct: 69  FKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKS---LELAG------- 118

Query: 268 PPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPPAPT-PAPELEELSP 317
            P +PRRVAVPVLV+DGKPC            GP P AP  P+P    +SP
Sbjct: 119 HPLTPRRVAVPVLVRDGKPC-----------LGPGPGAPAFPSPYSAAVSP 158


>gi|31377777 NK2 homeobox 8 [Homo sapiens]
          Length = 239

 Score =  127 bits (320), Expect = 1e-29
 Identities = 77/149 (51%), Positives = 88/149 (59%), Gaps = 4/149 (2%)

Query: 186 AAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMK 245
           A  R+KRRVLFS+AQ  ELERRF+QQ+YLSAPERE LAS++ LTPTQVKIWFQNHRYK+K
Sbjct: 81  AEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLK 140

Query: 246 RQAKDKAAQQLQQEGGLGPPPPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPPA 305
           R A+   A +             P   RRV VPVLV+DG+PC  G      G A  Q   
Sbjct: 141 R-ARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEV-GTAAAQEKC 198

Query: 306 PTPAPELEELSPSPPALHGPGGGLAALDA 334
             P P      P  PA  GPG  L    A
Sbjct: 199 GAP-PAAACPLPGYPAF-GPGSALGLFPA 225


>gi|4502365 NK3 homeobox 2 [Homo sapiens]
          Length = 333

 Score =  108 bits (269), Expect = 9e-24
 Identities = 120/361 (33%), Positives = 154/361 (42%), Gaps = 71/361 (19%)

Query: 9   TPFSVSDILSPIEETYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQAATVAGMQPS 68
           T FS+  IL+  EE      G +  AP G  AP G AA+  A    P+     + G + +
Sbjct: 10  TSFSIQAILNKKEER-----GGL-AAPEGRPAPGGTAASVAA---APAVCCWRLFGERDA 60

Query: 69  HAMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQFP---------------HGAMGSYCNG 113
            A+ G   +  A+ A    AA  T   P G                     GA G+   G
Sbjct: 61  GALGGAEDSLLASPAGTRTAAGRTAESPEGWDSDSALSEENESRRRCADARGASGAGLAG 120

Query: 114 GLGNMG----ELPAYTDGMRGGAATGWYGANPDPRYSSISRFMGP-----SAGVNVAGMG 164
           G  ++G    EL A  D     A     G +     +S+S    P       G   A + 
Sbjct: 121 GSLSLGQPVCELAASKDLEEEAA-----GRSDSEMSASVSGDRSPRTEDDGVGPRGAHVS 175

Query: 165 SLTGIADAAKSLGPLHAAA-----AAAAPRRKR-RVLFSQAQVYELERRFKQQKYLSAPE 218
           +L   A      GP   A      AA  PR+KR R  FS AQV+ELERRF  Q+YLS PE
Sbjct: 176 ALCSGAGGGGGSGPAGVAEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPE 235

Query: 219 REHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGLGPPPPPPPSPRRVAVP 278
           R  LA+ + LT TQVKIWFQN RYK KR  +  AA  L             P+ ++VAV 
Sbjct: 236 RADLAASLKLTETQVKIWFQNRRYKTKR--RQMAADLLAS----------APAAKKVAVK 283

Query: 279 VLVKDGKPCQNGASTPTPGQAGPQPPAPTPAPELEELSPS--PPALHGPGGGLAALDAAA 336
           VLV+D +          PG+   +PP+  P      L PS   P    PG  L+   AAA
Sbjct: 284 VLVRDDQ------RQYLPGEV-LRPPSLLP------LQPSYYYPYYCLPGWALSTCAAAA 330

Query: 337 G 337
           G
Sbjct: 331 G 331


>gi|116805350 homeo box (H6 family) 1 [Homo sapiens]
          Length = 348

 Score = 95.5 bits (236), Expect = 6e-20
 Identities = 77/239 (32%), Positives = 106/239 (44%), Gaps = 31/239 (12%)

Query: 98  GVSQFPHGAMGSYCNGGLGNMGELPAYTDGMRGGAATGWYGANPDP----RYSSISRFMG 153
           G +++   A G Y  G   +  +  +   G   G A G +   P P    R ++     G
Sbjct: 112 GAARWYPRAHGGYGGGLSPDTSDRDSPETGEEMGRAEGAWPRGPGPGAVQREAAELAARG 171

Query: 154 PSAGVNVAGMGSLTGIADAAKSLGPLHAAAAAAAPRRKR-RVLFSQAQVYELERRFKQQK 212
           P+AG   A     + +A+   + G           R+K+ R +FS++QV++LE  F  ++
Sbjct: 172 PAAGTEEA-----SELAEVPAAAGETRGGVGVGGGRKKKTRTVFSRSQVFQLESTFDLKR 226

Query: 213 YLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQ-AKDKAAQQLQQEGGLGPPPPPPPS 271
           YLS+ ER  LA+ + LT TQVKIWFQN R K KRQ A +  A  L           PP +
Sbjct: 227 YLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLAAELEAASLS----------PPGA 276

Query: 272 PRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPPAPTPAPELEELSPSPPALHGPGGGLA 330
            R V VPVL  +  P    A           PPA  P P        PP L G  G LA
Sbjct: 277 QRLVRVPVLYHESPPAAAAAG----------PPATLPFPLAPAAPAPPPPLLGFSGALA 325



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 33/111 (29%), Positives = 39/111 (35%), Gaps = 35/111 (31%)

Query: 261 GLGPPPPPPPSPRRVAVPVLVKDG-----------------KPCQNGASTPTPGQ----- 298
           GLGP PPP P P     P  +  G                  P  +   +P  G+     
Sbjct: 93  GLGPRPPPGPGP-----PFALGCGGAARWYPRAHGGYGGGLSPDTSDRDSPETGEEMGRA 147

Query: 299 AGPQPPAPTPAPELEELSPSPPALHGPGGG------LAALDAAAGEYSGGV 343
            G  P  P P     E +    A  GP  G      LA + AAAGE  GGV
Sbjct: 148 EGAWPRGPGPGAVQREAAEL--AARGPAAGTEEASELAEVPAAAGETRGGV 196


>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
          Length = 411

 Score = 92.0 bits (227), Expect = 7e-19
 Identities = 104/365 (28%), Positives = 132/365 (36%), Gaps = 60/365 (16%)

Query: 4   SPKHTTPFSVSDILSPIEETYKKFSGAMDG--AP----PGLGAPLGAAAAYRAPPPGPS- 56
           +P   T FSV DIL P +   ++    + G  AP    P   AP   A A    PP    
Sbjct: 38  APLRPTSFSVLDILDPNKFNSRRRRCVLLGPVAPAACAPCASAPCAPAPAASGRPPRAEE 97

Query: 57  --------SQAATVAGMQPSHAMAGHNAAAAAAAAAAAAAAAATYHMPPGVS-------- 100
                   +     AG +P +A     A  A        ++    H P   S        
Sbjct: 98  LERRALAGAGGVGAAGAEPPNAGDPFKAGEAETNDTNGYSSGGGGHSPSADSGDEVPDDE 157

Query: 101 -----QFPHGAMGSYCNGGLGNMGELPAYTDGMRGGA-------ATGWYGANPDPRYSSI 148
                + P            G  G L A   G +G A       AT    A P PR +S 
Sbjct: 158 DDDEDEAPETEAARGAEEARGGGGGLGARGSGCQGAAETDASPGATVDEAAAPGPRENSP 217

Query: 149 SRFMGPSAGVNVAGMGSLT--GIADAAKSLGPLHAAAAAAAPRRKRRVLFSQAQVYELER 206
               GP  G    G    T  G A AAK       + + +   R+ R  F+  Q+  LE 
Sbjct: 218 VA-QGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALEN 276

Query: 207 RFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGLGPPP 266
           +FK  +YLS  ER +LA  + LT TQVKIWFQN R K K+Q  +  A      GG G P 
Sbjct: 277 KFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQ--NPGADTSAPTGGGGGPG 334

Query: 267 PPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPPAPTPAPELEELSPSPPALHGPG 326
           P                      G  T  PG   P  P+P     L    P+    HGPG
Sbjct: 335 PGA--------------------GPGTGLPGGLSPLSPSPPMGAPLGMHGPAGYPAHGPG 374

Query: 327 GGLAA 331
           G + A
Sbjct: 375 GLVCA 379


>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 814

 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 104/365 (28%), Positives = 132/365 (36%), Gaps = 60/365 (16%)

Query: 4   SPKHTTPFSVSDILSPIEETYKKFSGAMDG--AP----PGLGAPLGAAAAYRAPPPGPS- 56
           +P   T FSV DIL P +   ++    + G  AP    P   AP   A A    PP    
Sbjct: 441 APLRPTSFSVLDILDPNKFNSRRRRCVLLGPVAPAACAPCASAPCAPAPAASGRPPRAEE 500

Query: 57  --------SQAATVAGMQPSHAMAGHNAAAAAAAAAAAAAAAATYHMPPGVS-------- 100
                   +     AG +P +A     A  A        ++    H P   S        
Sbjct: 501 LERRALAGAGGVGAAGAEPPNAGDPFKAGEAETNDTNGYSSGGGGHSPSADSGDEVPDDE 560

Query: 101 -----QFPHGAMGSYCNGGLGNMGELPAYTDGMRGGA-------ATGWYGANPDPRYSSI 148
                + P            G  G L A   G +G A       AT    A P PR +S 
Sbjct: 561 DDDEDEAPETEAARGAEEARGGGGGLGARGSGCQGAAETDASPGATVDEAAAPGPRENSP 620

Query: 149 SRFMGPSAGVNVAGMGSLT--GIADAAKSLGPLHAAAAAAAPRRKRRVLFSQAQVYELER 206
               GP  G    G    T  G A AAK       + + +   R+ R  F+  Q+  LE 
Sbjct: 621 VA-PGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALEN 679

Query: 207 RFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGLGPPP 266
           +FK  +YLS  ER +LA  + LT TQVKIWFQN R K K+Q  +  A      GG G P 
Sbjct: 680 KFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQ--NPGADTSAPTGGGGGPG 737

Query: 267 PPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPPAPTPAPELEELSPSPPALHGPG 326
           P                      G  T  PG   P  P+P     L    P+    HGPG
Sbjct: 738 PGA--------------------GPGTGLPGGLSPLSPSPPMGAPLGMHGPAGYPAHGPG 777

Query: 327 GGLAA 331
           G + A
Sbjct: 778 GLVCA 782


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 99/325 (30%), Positives = 134/325 (41%), Gaps = 65/325 (20%)

Query: 44  AAAAYRAPPPGPSSQAATVAGMQPSHAMAGHNA-AAAAAAAAAAAAAAATYHMPPGVSQF 102
           AA     P PG         G    H    H+A   AAAAAAAAAAAAA   +  G+   
Sbjct: 85  AAHCALLPKPGFLGAGGGGGGTGGGHGGPHHHAHPGAAAAAAAAAAAAAAGGLALGLH-- 142

Query: 103 PHGAMGSYCNGGLGNMGELPAYTDGMRG----GAATGWYGANPDPRYSSISRFMG--PSA 156
           P GA G     G G   +   Y   + G     AA    G +P   YS   +  G  P+ 
Sbjct: 143 PGGAQG-----GAGLPAQAALYGHPVYGYSAAAAAAALAGQHPALSYS-YPQVQGAHPAH 196

Query: 157 GVNVAGMGSLTGIADA---AKSLGPL---------HAAAAAAAPRRKRRVLFSQAQVYEL 204
             +   +G+ T   D    A + G +          A +      R+ R  F+  Q+ EL
Sbjct: 197 PADPIKLGAGTFQLDQWLRASTAGMILPKMPDFNSQAQSNLLGKCRRPRTAFTSQQLLEL 256

Query: 205 ERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKR--QAKDKAAQQLQQEGG- 261
           E +FK  KYLS P+R  +A+ + LT TQVKIWFQN R K KR  +AK++AAQ+ +++ G 
Sbjct: 257 EHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQAAQEAEKQKGG 316

Query: 262 -----------------LGPPPPPPPSPRRVAVPVLVKDGK-----------PCQNGAST 293
                            LGPP P      R    +   D +           P  NGAS 
Sbjct: 317 GGGAGKGGAEEPGAEELLGPPAPGDKGSGRRLRDLRDSDPEEDEDEDDEDHFPYSNGASV 376

Query: 294 -------PTPGQAGPQPPAPTPAPE 311
                   +   + P  P+  PAP+
Sbjct: 377 HAASSDCSSEDDSPPPRPSHQPAPQ 401



 Score = 29.3 bits (64), Expect = 5.6
 Identities = 22/56 (39%), Positives = 23/56 (41%), Gaps = 4/56 (7%)

Query: 290 GASTPTPGQAGP---QPPAPTPAPELEELSPSPPALHGPGGGLAALDAAAGEYSGG 342
           GAS  T G   P   +PPA  PA  L   SPSPP L      L       G   GG
Sbjct: 49  GASGGTSGSCSPASSEPPA-APADRLRAESPSPPRLLAAHCALLPKPGFLGAGGGG 103


>gi|169636435 caudal type homeobox 2 [Homo sapiens]
          Length = 313

 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 92/305 (30%), Positives = 122/305 (40%), Gaps = 61/305 (20%)

Query: 40  APLGAAAAYRAPPPGPSSQAATVA-------GMQPSHAMAGHNAAA-----AAAAAAAAA 87
           A   AA    A  PGPS  AA  A       G  P  A A  NA A      + AAA   
Sbjct: 48  AAAAAANLDSAQSPGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGY 107

Query: 88  AAAATYHMPPGVSQFPHG-AMGSYCNGGLGNMGELPAYTDGMRGGAATGWYGA-NPDPRY 145
           ++ A YH        PH  A    C  GL     L     G  G AAT      +P  + 
Sbjct: 108 SSPADYHPHHHPHHHPHHPAAAPSCASGL-----LQTLNPGPPGPAATAAAEQLSPGGQR 162

Query: 146 SSISRFMGPSAGVNVAGMGSLTGIADAAKSLGPLHAAAAAAAPRRKRRVLFSQAQVYELE 205
            ++  +M   A                 +SLG    +      + K RV+++  Q  ELE
Sbjct: 163 RNLCEWMRKPA----------------QQSLG----SQVKTRTKDKYRVVYTDHQRLELE 202

Query: 206 RRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGLGPP 265
           + F   +Y++   +  LA+ + L+  QVKIWFQN R K ++  K K  QQ QQ+    PP
Sbjct: 203 KEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKKKLQQQQQQQ----PP 258

Query: 266 PPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPPAPTPAPELEELSP-SPPALHG 324
            PPPP P            +P Q     P PG     P   +P   L+   P S P + G
Sbjct: 259 QPPPPPP------------QPPQ-----PQPGPLRSVPEPLSPVSSLQASVPGSVPGVLG 301

Query: 325 PGGGL 329
           P GG+
Sbjct: 302 PTGGV 306


>gi|19923352 NK3 homeobox 1 [Homo sapiens]
          Length = 234

 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 41/75 (54%), Positives = 49/75 (65%)

Query: 188 PRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQ 247
           P+++ R  FS  QV ELER+F  QKYLSAPER HLA  + LT TQVKIWFQN RYK KR+
Sbjct: 123 PQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRK 182

Query: 248 AKDKAAQQLQQEGGL 262
                   L++   L
Sbjct: 183 QLSSELGDLEKHSSL 197


>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 653

 Score = 82.0 bits (201), Expect = 7e-16
 Identities = 65/193 (33%), Positives = 81/193 (41%), Gaps = 25/193 (12%)

Query: 141 PDPRYSSISRFMGPSAGVNVAGMGSLT--GIADAAKSLGPLHAAAAAAAPRRKRRVLFSQ 198
           P PR +S     GP  G    G    T  G A AAK       + + +   R+ R  F+ 
Sbjct: 48  PGPRENSPVA-PGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTY 106

Query: 199 AQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQ 258
            Q+  LE +FK  +YLS  ER +LA  + LT TQVKIWFQN R K K+Q  +  A     
Sbjct: 107 EQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQ--NPGADTSAP 164

Query: 259 EGGLGPPPPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPPAPTPAPELEELSPS 318
            GG G P P                      G  T  PG   P  P+P     L    P+
Sbjct: 165 TGGGGGPGPGA--------------------GPGTGLPGGLSPLSPSPPMGAPLGMHGPA 204

Query: 319 PPALHGPGGGLAA 331
               HGPGG + A
Sbjct: 205 GYPAHGPGGLVCA 217


>gi|84570137 homeobox B3 [Homo sapiens]
          Length = 431

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 86/317 (27%), Positives = 118/317 (37%), Gaps = 32/317 (10%)

Query: 52  PPGPSSQAAT-VAGMQPSHAMAGHNAAAAAAAAAAA---------AAAAATYHMPPGV-- 99
           PP P  QAAT + G     A +  +   AA  A +            A      PPG   
Sbjct: 32  PPQPPFQAATHLEGDYQRSACSLQSLGNAAPHAKSKELNGSCMRPGLAPEPLSAPPGSPP 91

Query: 100 -SQFPHGAMGSYCNGGLGNMGELPAYTDGMRGGAATGWYGANPDPRYSSISRFMGPSA-- 156
            S  P  A  +  NGG  +    P    G         +    + R +S  +   P    
Sbjct: 92  PSAAPTSATSNSSNGGGPSKSGPPKCGPGTNSTLTKQIFPWMKESRQTSKLKNNSPGTAE 151

Query: 157 ----GVNVAGMGSLTGIADAAKSLGPLHAAAAAAAPRRKRRVLFSQAQVYELERRFKQQK 212
               G    G G   G        G    +   +A  ++ R  ++ AQ+ ELE+ F   +
Sbjct: 152 GCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNR 211

Query: 213 YLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGLGPPPPPPPSP 272
           YL  P R  +A++++L+  Q+KIWFQN R K K   KD+ A+ L    G   P   PP P
Sbjct: 212 YLCRPRRVEMANLLNLSERQIKIWFQNRRMKYK---KDQKAKGLASSSGGPSPAGSPPQP 268

Query: 273 RRVAVPVLVKDGKPCQNGASTPTPGQAGPQPPAPTPAPELEELSPS--PPALHGPGGGLA 330
            +     +        N   + TP    P PPA   A +     PS   P L G G    
Sbjct: 269 MQSTAGFM--------NALHSMTPSYESPSPPAFGKAHQNAYALPSNYQPPLKGCGAPQK 320

Query: 331 ALDAAAGEYSGGVLGAN 347
                A EY   VL AN
Sbjct: 321 YPPTPAPEYEPHVLQAN 337


>gi|4758168 distal-less homeobox 2 [Homo sapiens]
          Length = 328

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 75/315 (23%), Positives = 114/315 (36%), Gaps = 40/315 (12%)

Query: 23  TYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQAATVAGMQPSHAMAGHNAAAAAAA 82
           TY +      G   G G    ++++   P   P+   +T       +    H A      
Sbjct: 22  TYHQHQQPPSGGGAGPGGNSSSSSSLHKPQESPTLPVSTATDSS-YYTNQQHPAGGGGGG 80

Query: 83  AAAAAAAAATYHMPPGVSQFPHGAMGSYCNGGLGNMGELPAYTDGMRGGAATGWYGANPD 142
            +  A   +  +   G++  P+ A  SY      ++G   AYT     G ++    AN +
Sbjct: 81  GSPYAHMGSYQYQASGLNNVPYSAKSSY------DLGYTAAYTSYAPYGTSSS--PANNE 132

Query: 143 PRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLGPLHAAAAAAAPRRKRRVLFSQAQVY 202
           P    +                              +          RK R ++S  Q+ 
Sbjct: 133 PEKEDLEP---------------------------EIRIVNGKPKKVRKPRTIYSSFQLA 165

Query: 203 ELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGL 262
            L+RRF++ +YL+ PER  LA+ + LT TQVKIWFQN R K K+  K       Q  G  
Sbjct: 166 ALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPSEQHPGAS 225

Query: 263 GPPPPPPPSPRRVAVPVLVKDGKPCQ-NGASTPTPGQAGPQPPAPTPAPELEELSPSPPA 321
             PP   P    V+ P     G P +  G   P  G +G      +P+        + P 
Sbjct: 226 ASPPCASPP---VSAPASWDFGVPQRMAGGGGPGSGGSGAGSSGSSPSSAASAFLGNYPW 282

Query: 322 LHGPGGGLAALDAAA 336
            H   G  + L A A
Sbjct: 283 YHQTSGSASHLQATA 297


>gi|111120318 NK6 transcription factor related, locus 1 [Homo
           sapiens]
          Length = 367

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 77/260 (29%), Positives = 109/260 (41%), Gaps = 55/260 (21%)

Query: 9   TPFSVSDILSPIEETYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQAATVAGMQPS 68
           TP  ++DILS                P   GA L +A+     P G SS ++       S
Sbjct: 94  TPHGINDILS------------RPSMPVASGAALPSAS-----PSGSSSSSS-------S 129

Query: 69  HAMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQF--------PHGAMGSYCNGGLGNMGE 120
            A A   +AAAAAAAAAAAAA++   +  G+ +F        P G   S     +  +G 
Sbjct: 130 SASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGR 189

Query: 121 LPAYTDGMRGGAATGWYGANPDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLGPLH 180
            P     + G     W G    P +        P         GS+    D         
Sbjct: 190 YPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPH-------QGSILLDKDGK------- 235

Query: 181 AAAAAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNH 240
                   R+  R  FS  Q++ LE+ F+Q KYL+ PER  LA  + +T +QVK+WFQN 
Sbjct: 236 --------RKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNR 287

Query: 241 RYK-MKRQAKDKAAQQLQQE 259
           R K  K+ A + A  + +Q+
Sbjct: 288 RTKWRKKHAAEMATAKKKQD 307


>gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]
          Length = 330

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 86/301 (28%), Positives = 127/301 (42%), Gaps = 47/301 (15%)

Query: 3   LSPKHTTP--FSVSDIL-SPIEETYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQA 59
           L P H  P  F +  IL SP +      +  +     GLG  +G A  Y     G  S A
Sbjct: 9   LHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYG----GGGSAA 64

Query: 60  ATVAGMQPSHAMAGHNAAAAAAAAAAAAAAA---ATYHMPPGVSQFPHGAMGSYCNGGLG 116
           AT AG   ++   G       A    A +      +Y++   ++  P    G   +GG G
Sbjct: 65  ATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSSGGAG 124

Query: 117 NMG-----ELPAYTDGMRGGAATGWYGANPDPRYSSISRFMGPSAGVNVAGMGSLTGIAD 171
            +       +PA+      GA      A+P P  + +       A   + G+ +LTG+  
Sbjct: 125 ALSAAGVIRVPAHRP--LAGAV-----AHPQPLATGLPTVPSVPA---MPGVNNLTGLTF 174

Query: 172 A--------AKSLGPLHAAAAAAAPRRKR-RVLFSQAQVYELERRFKQQKYLSAPEREHL 222
                     K     H       P++K+ R  F++ Q+ ELE+RF +QKYL++ ER  L
Sbjct: 175 PWMESNRRYTKDRFTGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAAL 234

Query: 223 ASMIHLTPTQVKIWFQNHRYKMKRQ-AKDKAAQ---------QLQQEG---GLGPPPPPP 269
           A  + +T  QVK WFQN R K +RQ A+++ A+         QLQQE     L  P P  
Sbjct: 235 AKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLAQPLPAD 294

Query: 270 P 270
           P
Sbjct: 295 P 295


>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
          Length = 283

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 48/143 (33%), Positives = 69/143 (48%), Gaps = 20/143 (13%)

Query: 181 AAAAAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNH 240
           A AA     ++ R  +++AQ+ ELE+ F   KY+S P R  LA M++LT   +KIWFQN 
Sbjct: 138 AYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNR 197

Query: 241 RYKMKRQAKDKAAQQLQQEGGLG-------------------PPPPPPPSPRRVAVPVLV 281
           R K K++ +DK        GG G                   PPPPPP      A PV  
Sbjct: 198 RMKWKKE-EDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLALPPPPPPGGAVPPAAPVAA 256

Query: 282 KDGKPCQNGASTPTPGQAGPQPP 304
           ++G+     +++P P    P+ P
Sbjct: 257 REGRLPPGLSASPQPSSVAPRRP 279


>gi|157743259 H6 family homeobox 3 [Homo sapiens]
          Length = 357

 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 57/159 (35%), Positives = 78/159 (49%), Gaps = 16/159 (10%)

Query: 155 SAGVNVAGMGSLTGIADAAKSLGPLHAAAAAAAPRRKRRVLFSQAQVYELERRFKQQKYL 214
           +AG +V    +  G  D  K  G        A  ++K R +FS++QV++LE  F  ++YL
Sbjct: 195 AAGASVGAAAATPGAEDWKK--GAESPEKKPACRKKKTRTVFSRSQVFQLESTFDMKRYL 252

Query: 215 SAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQ-AKDKAAQQLQQEGGLGPPPPPPPSPR 273
           S+ ER  LA+ +HLT TQVKIWFQN R K KRQ A +  A  L              + R
Sbjct: 253 SSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAA----------AQR 302

Query: 274 RVAVPVLVKDGKPCQNGASTPTPGQAGP--QPPAPTPAP 310
            V VP+L  +    + GA+    G   P  QP    P P
Sbjct: 303 IVRVPILYHENSAAE-GAAAAAAGAPVPVSQPLLTFPHP 340



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 21/81 (25%)

Query: 264 PPPPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPPAPTPAPELEELSPSPPALH 323
           PPPPPPP+P+     +     K   NG     P +  PQPP              P  L 
Sbjct: 18  PPPPPPPAPKESPFSI-----KNLLNGDHHRPPPK--PQPP--------------PRTLF 56

Query: 324 GPGGGLAALDAAAGEYSGGVL 344
            P    AA  AAA   + G L
Sbjct: 57  APASAAAAAAAAAAAAAKGAL 77



 Score = 29.3 bits (64), Expect = 5.6
 Identities = 21/56 (37%), Positives = 24/56 (42%), Gaps = 2/56 (3%)

Query: 48  YRAPPPGPSSQAATVAGMQPSHAMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQFP 103
           +  PPP P     T+    P+ A A   AAAAAAA  A   AA       G   FP
Sbjct: 41  HHRPPPKPQPPPRTL--FAPASAAAAAAAAAAAAAKGALEGAAGFALSQVGDLAFP 94


>gi|23510368 homeobox D11 [Homo sapiens]
          Length = 338

 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 85/296 (28%), Positives = 118/296 (39%), Gaps = 63/296 (21%)

Query: 8   TTPFS--VSDILSPIEETYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQAATVAGM 65
           T P+S  ++  + P+ E   +  G      P  G   G +A   +   GP        G 
Sbjct: 44  TFPYSSNLAPHVQPVREVAFRDYGLERAKWPYRGGGGGGSAGGGSSGGGPGGGGGGAGGY 103

Query: 66  QPSHAMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQF----------------PHGAMGS 109
            P +A A   AAAAAAAAAA  AA     +PP   +                 PHG  G+
Sbjct: 104 APYYAAA---AAAAAAAAAAEEAAMQRELLPPAGRRPDVLFKAPEPVCAAPGPPHGPAGA 160

Query: 110 YCN--GGLGNMGELPAYTDGM--------------------------------RGGAATG 135
             N    +G  G LP   D                                  R GA  G
Sbjct: 161 ASNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQPPPPPAPPQPEGAADKGDPRTGAGGG 220

Query: 136 WYGANPDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLGPLHAAAAAAAPRRKRRVL 195
             G +P  + +  S   G + G    G G   G A A KS     ++A A    RK+R  
Sbjct: 221 --GGSPCTKATPGSEPKGAAEGSGGDGEGP-PGEAGAEKS-----SSAVAPQRSRKKRCP 272

Query: 196 FSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDK 251
           +++ Q+ ELER F    Y++  +R  L+ M++LT  QVKIWFQN R K K+  +D+
Sbjct: 273 YTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDR 328



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 15/37 (40%), Positives = 18/37 (48%)

Query: 292 STPTPGQAGPQPPAPTPAPELEELSPSPPALHGPGGG 328
           + P P  AGPQPP P   P+ E  +       G GGG
Sbjct: 184 AAPGPPFAGPQPPPPPAPPQPEGAADKGDPRTGAGGG 220


>gi|13375632 homeobox D1 [Homo sapiens]
          Length = 328

 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 70/240 (29%), Positives = 96/240 (40%), Gaps = 34/240 (14%)

Query: 41  PLGAAAAYRAPPPGPSSQAATVAGMQPSHAMAGHNAAAAAAAAAAAAAAAATYHMP---- 96
           PL AA    +PP  P+  +       P +A      A    AA AAAA  A Y       
Sbjct: 55  PLAAARPSPSPPAAPARPSVPPPAA-PQYAQCTLEGAYEPGAAPAAAAGGADYGFLGSGP 113

Query: 97  ----PGV--------SQFPHGAMGSYCNGG-------------LGNMGELPAYTDGMRGG 131
               PGV            H A  +  +GG              G  G  PA       G
Sbjct: 114 AYDFPGVLGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAAFGEPGPFPACLKASADG 173

Query: 132 AATGWYGANPDPRYSSISRFMGPSAGVNVA-GMGSLTGIADAAKSLGPLHAAAAAAAPRR 190
               +  A+P P   +  + + P++G+  A        +   A   G L A   AA+P  
Sbjct: 174 HPGAFQTASPAP--GTYPKSVSPASGLPAAFSTFEWMKVKRNASKKGKL-AEYGAASPSS 230

Query: 191 KRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKD 250
             R  FS  Q+ ELE+ F   KYL+   R  +A+ +HL  TQVKIWFQN R K K++ ++
Sbjct: 231 AIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKKRERE 290


>gi|118582284 msh homeobox 1 [Homo sapiens]
          Length = 303

 Score = 75.1 bits (183), Expect = 9e-14
 Identities = 76/288 (26%), Positives = 110/288 (38%), Gaps = 39/288 (13%)

Query: 28  SGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQAATVAGMQPSHAMAG--HNAAAAAAAAAA 85
           +G    A     A +GA      P   PS    +V  +   H   G   +A A +    A
Sbjct: 29  AGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESALAPSEGVQA 88

Query: 86  AAAAAATYHMPPGVSQFPHGA-----MGSYCNGGLGNMGELPAYTDGMRGGAATGWYGAN 140
           A  +A    +PPG    P        +G +  GGL  + E                    
Sbjct: 89  AGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPE-------------------- 128

Query: 141 PDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLGPLHAAAAAAAPRRKRRVLFSQAQ 200
                 ++ +   P        M S       A+ L P           RK R  F+ AQ
Sbjct: 129 -----DALVKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQ 183

Query: 201 VYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEG 260
           +  LER+F+Q++YLS  ER   +S + LT TQVKIWFQN R K KR  ++   ++L+   
Sbjct: 184 LLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKR-LQEAELEKLK--- 239

Query: 261 GLGPPPPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPPAPTP 308
            +   P  PP+   ++ P+          GAS    G +GP   A  P
Sbjct: 240 -MAAKPMLPPAAFGLSFPLGGPAAVAAAAGAS--LYGASGPFQRAALP 284


>gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]
          Length = 284

 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 44/95 (46%), Positives = 59/95 (62%), Gaps = 13/95 (13%)

Query: 189 RRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQ- 247
           R+K R  FS++QV ELERRF +QKYL++ ER  LA  + +T  QVK WFQN R K +RQ 
Sbjct: 157 RKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQT 216

Query: 248 AKDKAAQQ---------LQQEG---GLGPPPPPPP 270
           A+++ A++         LQQ+     L PP PP P
Sbjct: 217 AEEREAERHRAGRLLLHLQQDALPRPLRPPLPPDP 251


>gi|4503615 even-skipped homeobox 1 [Homo sapiens]
          Length = 407

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 86/317 (27%), Positives = 115/317 (36%), Gaps = 33/317 (10%)

Query: 35  PPGLGAPLGAAAAYRAPPPGPSSQAATVAGMQPSHAMAGHNAAAAAAAAAAAAAAAATYH 94
           PP    P G  +  RA PP    +       +P   +AG  A   A    A AA      
Sbjct: 38  PPEKMVPRGCLSP-RAVPPATRERGGGGPEEEPVDGLAGSAAGPGAEPQVAGAAMLGPGP 96

Query: 95  MPPGVSQFPHGAMGSYCNGGLGNMGELPAYTDGMRGGAATGWYGANPDPRYSSISRFMGP 154
             P V         S  +       E+           ATG    N + ++S  S   G 
Sbjct: 97  PAPSVDSLSGQGQPSSSDTESDFYEEIEV---SCTPDCATG----NAEYQHSKGS---GS 146

Query: 155 SAGVNVAGMGSLT----GIADAAKSLGPLHAAAAAAAPRRKRRVLFSQAQVYELERRFKQ 210
            A V     GS T    G +    S G L  A +A+   R+ R  F++ Q+  LE+ F +
Sbjct: 147 EALVGSPNGGSETPKSNGGSGGGGSQGTL--ACSASDQMRRYRTAFTREQIARLEKEFYR 204

Query: 211 QKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQ--------AKDKAAQQLQQEGGL 262
           + Y+S P R  LA+ ++L  T +K+WFQN R K KRQ          D A          
Sbjct: 205 ENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAA 264

Query: 263 GPPPPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPP--------APTPAPELEE 314
                P P P  + +P     G    + AS      +G   P         P P PEL  
Sbjct: 265 AAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGSLRPLDTFRVLSQPYPRPELLC 324

Query: 315 LSPSPPALHGPGGGLAA 331
               PP   GP  GL A
Sbjct: 325 AFRHPPLYPGPAHGLGA 341


>gi|147901462 brain specific homeobox [Homo sapiens]
          Length = 233

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 39/85 (45%), Positives = 52/85 (61%), Gaps = 4/85 (4%)

Query: 189 RRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQA 248
           RRK R +FS +Q+  LE+RF+ Q+YLS PER  LA+ + L+ TQVK WFQN R K K+Q 
Sbjct: 110 RRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQL 169

Query: 249 KDKAAQQLQQEGGLGPPPPPPPSPR 273
           +    +    +G    P  P  SPR
Sbjct: 170 RKSQDEPKAPDG----PESPEGSPR 190


>gi|70608170 H6 family homeobox 2 [Homo sapiens]
          Length = 273

 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 36/67 (53%), Positives = 46/67 (68%)

Query: 181 AAAAAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNH 240
           A   A A ++K R +FS++QVY+LE  F  ++YLS+ ER  LAS + LT TQVK WFQN 
Sbjct: 141 AERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNR 200

Query: 241 RYKMKRQ 247
           R K KRQ
Sbjct: 201 RNKWKRQ 207


>gi|24497515 homeobox A3 isoform b [Homo sapiens]
          Length = 285

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 53/158 (33%), Positives = 74/158 (46%), Gaps = 16/158 (10%)

Query: 187 APRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKR 246
           A  ++ R  ++ AQ+ ELE+ F   +YL  P R  +A++++LT  Q+KIWFQN R K K+
Sbjct: 31  ASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 90

Query: 247 QAKDKAAQQLQQEGGLGP--PPPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQ-- 302
             K K    L   GG  P   P PP +   +     + +  P +    +P P    PQ  
Sbjct: 91  DQKGKG--MLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYE--PQSPPPFSKPPQGT 146

Query: 303 ---PPAPTPAPELEELSPSPPALHGPGGGLAALDAAAG 337
              PPA  PA  L   +P PP    P     A  A AG
Sbjct: 147 YGLPPASYPA-SLPSCAPPPP----PQKRYTAAGAGAG 179



 Score = 32.3 bits (72), Expect = 0.66
 Identities = 40/161 (24%), Positives = 57/161 (35%), Gaps = 42/161 (26%)

Query: 5   PKHTTPFSVSDILSPIEETYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQ---AAT 61
           P+   PFS      P + TY        G PP   A   A+    APPP P  +   A  
Sbjct: 133 PQSPPPFS-----KPPQGTY--------GLPP---ASYPASLPSCAPPPPPQKRYTAAGA 176

Query: 62  VAGMQP-----SHAMAGHNAAAAAAAAAAAAAAAATYHMPP--------GVSQFPHGAMG 108
            AG  P     +H + G+ +        +      +Y  P         G++  PH A G
Sbjct: 177 GAGGTPDYDPHAHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASG 236

Query: 109 SYCNGGLGNMGELPAYTDGMRGGAATGWYGANPDPRYSSIS 149
           +   GG G +G       G   G   G     P P Y+ ++
Sbjct: 237 AMDYGGAGPLG------SGHHHGPGPG----EPHPTYTDLT 267


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,427,478
Number of Sequences: 37866
Number of extensions: 1337963
Number of successful extensions: 27003
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 777
Number of HSP's successfully gapped in prelim test: 1108
Number of HSP's that attempted gapping in prelim test: 11869
Number of HSP's gapped (non-prelim): 10031
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.