NKX2-1 2227

Name: NKX2-1	Sequence: fasta or formatted (401aa)		NCBI GI: 118766339
Description: thyroid transcription factor 1 isoform 1		Referenced in: Homeobox and Related Proteins Lung Thyroid and Thyroid Hormone Receptor
Other entries for this name: alt prot [371aa] thyroid transcription factor 1 isoform 2
Composition: Amino acid Percentage Count Longest homopolymer A alanine 13.7 55 5 C cysteine 1.0 4 1 D aspartate 2.2 9 1 E glutamate 2.2 9 2 F phenylalanine 1.5 6 1 G glycine 13.7 55 8 H histidine 4.0 16 2 I isoleucine 1.5 6 1 K lysine 3.7 15 2 L leucine 6.5 26 2 M methionine 4.0 16 1 N asparagine 2.2 9 1 P proline 7.5 30 2 Q glutamine 9.5 38 4 R arginine 5.5 22 3 S serine 10.2 41 2 T threonine 3.0 12 2 V valine 4.0 16 1 W tryptophan 1.2 5 1 Y tyrosine 2.7 11 1			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 thyroid transcription factor 1 isoform 1 NKX2-1 0.923 thyroid transcription factor 1 isoform 2 NKX2-4 0.418 NK2 homeobox 4 NKX2-3 0.150 NK2 transcription factor related, locus 3 NKX2-2 0.141 NK2 transcription factor related, locus 2 NKX2-6 0.137 NK2 transcription factor related, locus 6 NKX2-5 0.132 NK2 transcription factor related, locus 5 NKX2-8 0.128 NK2 homeobox 8 NKX3-2 0.083 NK3 homeobox 2 NKX3-1 0.077 NK3 homeobox 1 MNX1 0.074 homeo box HB9 TLX2 0.067 T-cell leukemia homeobox 2 PHOX2B 0.067 paired-like homeobox 2b HLX 0.065 H2.0-like homeobox LBX1 0.065 ladybird homeobox 1 NKX1-2 0.063 NK1 homeobox 2 NKX1-2 0.063 PREDICTED: NK1 homeobox 2 NKX1-2 0.063 PREDICTED: NK1 homeobox 2 NKX1-2 0.063 PREDICTED: NK1 homeobox 2 HMX1 0.063 homeo box (H6 family) 1 HMX3 0.063 H6 family homeobox 3 HOXB3 0.062 homeobox B3 NKX1-1 0.062 PREDICTED: NK1 homeobox 1 NKX1-1 0.062 PREDICTED: NK1 homeobox 1 NKX1-1 0.062 PREDICTED: HPX-153 homeobox BSX 0.060 brain specific homeobox HMX2 0.059 H6 family homeobox 2 EMX1 0.059 empty spiracles homolog 1 PDX1 0.058 pancreatic and duodenal homeobox 1 DLX1 0.058 distal-less homeobox 1 isoform 1 Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.