Guide to the Human Genome
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Search of human proteins with 11056048

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11056048 doublesex and mab-3 related transcription factor 3
[Homo sapiens]
         (472 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11056048 doublesex and mab-3 related transcription factor 3 [...   960   0.0  
gi|154146231 DMRT-like family A2 [Homo sapiens]                       149   7e-36
gi|170763515 DMRT-like family A1 [Homo sapiens]                       137   3e-32
gi|195947401 doublesex and mab-3 related transcription factor 2 ...   109   6e-24
gi|5729806 doublesex and mab-3 related transcription factor 2 is...   109   6e-24
gi|153945850 doublesex and mab-3 related transcription factor 2 ...   109   6e-24
gi|94536830 DMRT-like family C2 [Homo sapiens]                        103   3e-22
gi|62241026 doublesex and mab-3 related transcription factor 1 [...   100   5e-21
gi|24308352 DMRT-like family B with proline-rich C-terminal, 1 [...    91   3e-18
gi|66529407 tensin [Homo sapiens]                                      49   8e-06
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    47   5e-05
gi|119943102 CREB binding protein isoform b [Homo sapiens]             45   1e-04
gi|119943104 CREB binding protein isoform a [Homo sapiens]             45   1e-04
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       44   2e-04
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       44   2e-04
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]     43   5e-04
gi|50345997 E1A binding protein p300 [Homo sapiens]                    43   7e-04
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    43   7e-04
gi|32307177 forkhead box G1 [Homo sapiens]                             42   0.001
gi|23503317 coiled-coil domain containing 96 [Homo sapiens]            42   0.001
gi|90903231 huntingtin [Homo sapiens]                                  42   0.001
gi|122937289 kinesin family member 18B [Homo sapiens]                  42   0.001
gi|238859557 regulatory factor X1 [Homo sapiens]                       42   0.002
gi|47578107 delangin isoform B [Homo sapiens]                          42   0.002
gi|47578105 delangin isoform A [Homo sapiens]                          42   0.002
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]       41   0.002
gi|91208420 bassoon protein [Homo sapiens]                             41   0.002
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]                 41   0.002
gi|47132519 Ras association and pleckstrin homology domains 1 is...    41   0.002
gi|27735129 hypothetical protein LOC148345 [Homo sapiens]              41   0.003

>gi|11056048 doublesex and mab-3 related transcription factor 3
           [Homo sapiens]
          Length = 472

 Score =  960 bits (2481), Expect = 0.0
 Identities = 472/472 (100%), Positives = 472/472 (100%)

Query: 1   MNGYGSPYLYMGGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCIL 60
           MNGYGSPYLYMGGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCIL
Sbjct: 1   MNGYGSPYLYMGGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCIL 60

Query: 61  IIERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQP 120
           IIERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQP
Sbjct: 61  IIERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQP 120

Query: 121 PRPAAELAAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSS 180
           PRPAAELAAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSS
Sbjct: 121 PRPAAELAAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSS 180

Query: 181 PDVAKSKGCFTPESPEIVSVEEGGYAVQKNGGNPESRPDSPKCHAEQNHLLIEGPSGTVS 240
           PDVAKSKGCFTPESPEIVSVEEGGYAVQKNGGNPESRPDSPKCHAEQNHLLIEGPSGTVS
Sbjct: 181 PDVAKSKGCFTPESPEIVSVEEGGYAVQKNGGNPESRPDSPKCHAEQNHLLIEGPSGTVS 240

Query: 241 LPFSLKANRPPLEVLKKIFPNQKPTVLELILKGCGGDLVSAVEVLLSSRSSVTGAERTSA 300
           LPFSLKANRPPLEVLKKIFPNQKPTVLELILKGCGGDLVSAVEVLLSSRSSVTGAERTSA
Sbjct: 241 LPFSLKANRPPLEVLKKIFPNQKPTVLELILKGCGGDLVSAVEVLLSSRSSVTGAERTSA 300

Query: 301 EPESLALPSNGHIFEHTLSSYPISSSKWSVGSAFRVPDTLRFSADSSNVVPSPLAGPLQP 360
           EPESLALPSNGHIFEHTLSSYPISSSKWSVGSAFRVPDTLRFSADSSNVVPSPLAGPLQP
Sbjct: 301 EPESLALPSNGHIFEHTLSSYPISSSKWSVGSAFRVPDTLRFSADSSNVVPSPLAGPLQP 360

Query: 361 PFPQPPRYPLMLRNTLARSQSSPFLPNDVTLWNTMTLQQQYQLRSQYVSPFPSNSTSVFR 420
           PFPQPPRYPLMLRNTLARSQSSPFLPNDVTLWNTMTLQQQYQLRSQYVSPFPSNSTSVFR
Sbjct: 361 PFPQPPRYPLMLRNTLARSQSSPFLPNDVTLWNTMTLQQQYQLRSQYVSPFPSNSTSVFR 420

Query: 421 SSPVLPARATEDPRISIPDDGCPFVSKQSIYTEDDYDERSDSSDSRTLNTSS 472
           SSPVLPARATEDPRISIPDDGCPFVSKQSIYTEDDYDERSDSSDSRTLNTSS
Sbjct: 421 SSPVLPARATEDPRISIPDDGCPFVSKQSIYTEDDYDERSDSSDSRTLNTSS 472


>gi|154146231 DMRT-like family A2 [Homo sapiens]
          Length = 542

 Score =  149 bits (375), Expect = 7e-36
 Identities = 141/429 (32%), Positives = 181/429 (42%), Gaps = 84/429 (19%)

Query: 9   LYMGGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVM 68
           L  G P+         RTPKCARCRNHGV+S LKGHKRYCR+KDC C KC LI ERQRVM
Sbjct: 50  LLRGPPLLLRAAEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVM 109

Query: 69  AAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAEL- 127
           AAQVALRRQQA E  E+     L+ L G    G A+AA         +   PPRPA E+ 
Sbjct: 110 AAQVALRRQQAQEENEA---RELQLLYG-TAEGLALAA--------ANGIIPPRPAYEVF 157

Query: 128 ------------AAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKSADN-----TEVF 170
                       A A A         G  +A+L K DL  + L       +      +  
Sbjct: 158 GSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPL 217

Query: 171 SDKDTDQ---RSSPDVAKSKG-------CFTPESPEIVSVEEGGY---AVQKNGGNPESR 217
           S    D     SSP+V    G        F+       S E GG    +    GG  E  
Sbjct: 218 SPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDS 277

Query: 218 PDSPKCHAEQNHLLIEGPSGTVSLPFSL-----KANRPPLEVLKKIFPNQKPTVLELILK 272
           P S      ++    +   G  +    L        R PL++L ++FP  +  VLEL+L+
Sbjct: 278 PGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQ 337

Query: 273 GCGGDLVSAVEVLLSSRSSVTGAERTSAEPESLALPSNGHIFEHTLSSYPISSSKWSVGS 332
           GCGGD+V A+E +L+       A    A P                        K +VG+
Sbjct: 338 GCGGDVVQAIEQVLNHHRGGLAAGLGPAAP----------------------PDKAAVGA 375

Query: 333 AFRVPDTLRFSADSSNV---------VPSPL-AGPLQPPFPQP----PRYPLMLRNTLAR 378
           A    D      D++           +P+PL AGP  PP  +P       P  L +  +R
Sbjct: 376 AAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSR 435

Query: 379 SQSSPFLPN 387
           S  SP  PN
Sbjct: 436 SAFSPLQPN 444


>gi|170763515 DMRT-like family A1 [Homo sapiens]
          Length = 504

 Score =  137 bits (344), Expect = 3e-32
 Identities = 100/280 (35%), Positives = 137/280 (48%), Gaps = 20/280 (7%)

Query: 25  RTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLE 84
           RTPKCARCRNHGV+S LKGHKR+CR++DC C KC LI ERQRVMAAQVALRRQQA E  E
Sbjct: 93  RTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEESE 152

Query: 85  SLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAEPQPGAL 144
           +     L       PPG   A+     A  P     P   A L   A  + +    P   
Sbjct: 153 ARGLQRLLCSGLSWPPGGR-ASGGGGRAENPQSTGGPAAGAALGLGALRQASGSATPAFE 211

Query: 145 QAQLAKP-DLTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKGCFTPES--------- 194
             Q   P +  E++    +S  N +      + Q      ++S G    +S         
Sbjct: 212 VFQQDYPEEKQEQKESKCESCQNGQEELISKSHQLYLGSSSRSNGVIGKQSIGSSISEYS 271

Query: 195 ---PEIVSVEEGGYAVQKNGG--NPESRPDSPKCHAEQNHLLIEGPSGTVSLPFSLKANR 249
                I+S   G    +++GG  +P S   S      ++  + +  +   SLP      R
Sbjct: 272 NKPDSILSPHPG----EQSGGEESPRSLSSSDLESGNESEWVKDLTATKASLPTVSSRPR 327

Query: 250 PPLEVLKKIFPNQKPTVLELILKGCGGDLVSAVEVLLSSR 289
            PL++L KIFPN + + LE IL+ C GD+V A+E +L+ +
Sbjct: 328 DPLDILTKIFPNYRRSRLEGILRFCKGDVVQAIEQVLNGK 367


>gi|195947401 doublesex and mab-3 related transcription factor 2
           isoform 1 [Homo sapiens]
          Length = 226

 Score =  109 bits (272), Expect = 6e-24
 Identities = 54/99 (54%), Positives = 63/99 (63%), Gaps = 24/99 (24%)

Query: 12  GGPVSQPPRAP------------------------LQRTPKCARCRNHGVLSWLKGHKRY 47
           GGP  +PP AP                        L RTPKCARCRNHGV+S LKGHKR+
Sbjct: 82  GGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRF 141

Query: 48  CRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESL 86
           CR++DC C  C+L++ERQRVMAAQVALRRQQA E  + L
Sbjct: 142 CRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL 180


>gi|5729806 doublesex and mab-3 related transcription factor 2
           isoform 1 [Homo sapiens]
          Length = 226

 Score =  109 bits (272), Expect = 6e-24
 Identities = 54/99 (54%), Positives = 63/99 (63%), Gaps = 24/99 (24%)

Query: 12  GGPVSQPPRAP------------------------LQRTPKCARCRNHGVLSWLKGHKRY 47
           GGP  +PP AP                        L RTPKCARCRNHGV+S LKGHKR+
Sbjct: 82  GGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRF 141

Query: 48  CRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESL 86
           CR++DC C  C+L++ERQRVMAAQVALRRQQA E  + L
Sbjct: 142 CRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL 180


>gi|153945850 doublesex and mab-3 related transcription factor 2
           isoform 2 [Homo sapiens]
          Length = 561

 Score =  109 bits (272), Expect = 6e-24
 Identities = 54/99 (54%), Positives = 63/99 (63%), Gaps = 24/99 (24%)

Query: 12  GGPVSQPPRAP------------------------LQRTPKCARCRNHGVLSWLKGHKRY 47
           GGP  +PP AP                        L RTPKCARCRNHGV+S LKGHKR+
Sbjct: 82  GGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRF 141

Query: 48  CRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESL 86
           CR++DC C  C+L++ERQRVMAAQVALRRQQA E  + L
Sbjct: 142 CRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGL 180


>gi|94536830 DMRT-like family C2 [Homo sapiens]
          Length = 367

 Score =  103 bits (257), Expect = 3e-22
 Identities = 51/105 (48%), Positives = 63/105 (60%)

Query: 19  PRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQ 78
           PR  + R+P CARCRNHGV + LKGHKR C F+ C C KC+LI+ER+RVMAAQVALRRQQ
Sbjct: 32  PRRAISRSPTCARCRNHGVTAHLKGHKRLCLFQACECHKCVLILERRRVMAAQVALRRQQ 91

Query: 79  ANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRP 123
             +  + L+     +   P         PQ P   +   PQP  P
Sbjct: 92  EAQLKKHLMRRGEASPKAPNHFRKGTTQPQVPSGKENIAPQPQTP 136


>gi|62241026 doublesex and mab-3 related transcription factor 1
           [Homo sapiens]
          Length = 373

 Score = 99.8 bits (247), Expect = 5e-21
 Identities = 54/104 (51%), Positives = 63/104 (60%), Gaps = 12/104 (11%)

Query: 25  RTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLE 84
           R PKCARCRNHG  S LKGHKR+C ++DC C+KC LI ERQRVMAAQVALRRQQA E   
Sbjct: 72  RLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEEL 131

Query: 85  SL-----IPDSLRAL-------PGPPPPGDAVAAPQPPPASQPS 116
            +     +P +   L         P    +     QPPPAS P+
Sbjct: 132 GISHPIPLPSAAELLVKRENNGSNPCLMTECSGTSQPPPASVPT 175


>gi|24308352 DMRT-like family B with proline-rich C-terminal, 1
           [Homo sapiens]
          Length = 342

 Score = 90.5 bits (223), Expect = 3e-18
 Identities = 64/165 (38%), Positives = 76/165 (46%), Gaps = 29/165 (17%)

Query: 25  RTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLE 84
           RTPKC+RCRNHG L  +KGH   CR+K C CEKC LI ERQ++MAAQ  L+ Q A E  E
Sbjct: 7   RTPKCSRCRNHGFLVPVKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQAAEEEQE 66

Query: 85  SLI----------------------PDSLRALPGPPPPGDAVAAPQPPPAS----QPSQP 118
           + +                        SLR L    P GDA   P+   A+    QP + 
Sbjct: 67  AALCAQGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRG 126

Query: 119 QPPRPAAELAAAAALRWTAEPQPGALQA--QLAKPDLTEERLGDG 161
           + P P A L      R   EP   A  A   LA P    E  G G
Sbjct: 127 RNPGPRA-LQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSG 170


>gi|66529407 tensin [Homo sapiens]
          Length = 1735

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 94/396 (23%), Positives = 146/396 (36%), Gaps = 83/396 (20%)

Query: 80   NESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAEP 139
            N+   S  P S  +LP   P   +   PQ PPAS P     P  + + A +   R T E 
Sbjct: 806  NQDFHSKSPAS-SSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSR-TPEE 863

Query: 140  QP----GALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRS-------SPDVAKSKG 188
            +P    G +  ++A     E++  +  +       SD   + +S       SP V     
Sbjct: 864  EPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVRSPVQ 923

Query: 189  CFTPESPEIVSVEEGGYAVQKN------------GGNPESRPDSPKCHAEQNHLLIEGPS 236
            C +PE    +++  GG   + +            G +P S P S           +  P 
Sbjct: 924  CVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSG----------VRSPP 973

Query: 237  GTVSLPFSLKANRP--PLEVL--------KKIFPNQKPTVLELILKGCGGDLVSAVEVLL 286
            G    P S    +P  P ++L        ++I P +    + + L       V +V    
Sbjct: 974  GLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESV---- 1029

Query: 287  SSRSSVTGAERTSAEPESLALPSN---GH---IFEHTLSSYPISSSKWSVGSAFRVPDTL 340
             +R++V G     +EP+S + P+    GH   +   TL    +S S  S  S        
Sbjct: 1030 -ARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPI------ 1082

Query: 341  RFSADSSNVVPSPLAGPLQPPFPQPPRYPLMLRNTLARSQSSPFLPNDVTLWNTMTLQQQ 400
              SADS++V   P +G      P+ P  PL+     + S   P          + + Q+ 
Sbjct: 1083 -LSADSTSVGSFP-SGESSDQGPRTPTQPLLESGFRSGSLGQP----------SPSAQRN 1130

Query: 401  YQ-------LRSQYVSPFPSNSTSVFRSSPVLPARA 429
            YQ       + S Y S  P  S   F SSP   ARA
Sbjct: 1131 YQSSSPLPTVGSSYSS--PDYSLQHFSSSPESQARA 1164


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
          Length = 2462

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 86/344 (25%), Positives = 119/344 (34%), Gaps = 56/344 (16%)

Query: 88   PDSLRALPGPPPPGDAVAAPQPPPA-SQPSQPQP--PRPAAELAAAAALRWTAEPQPGAL 144
            P+ + A   P P  +A  AP PPPA   PS P P  P+   E   AAA        P   
Sbjct: 770  PEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAA--------PPVE 821

Query: 145  QAQLAKPDLTEERLGD-GKSADNTEVFSDKDTDQRSSPDVAKSKGCFTPESPEIVSVEEG 203
            + +  KP   EE   D GK+ +  +    ++ ++  +          T E       +EG
Sbjct: 822  EGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEG 881

Query: 204  G---YAVQKNGGNPESRPDSPKCHAEQ---------NHLLIEGPS-----------GTVS 240
            G       K+ G P+    S  C A++         N LL   PS            +  
Sbjct: 882  GSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQ 941

Query: 241  LPFSLK------ANRPPLEVLKKIFPNQK---PTVLELILKGCGGDLVSAVEVLLSSRSS 291
             P  LK      A  PP++V K   P ++   PT           +L    +      SS
Sbjct: 942  KPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSS 1001

Query: 292  VTGAERTSAEP--ESLALPSNGHIFEHTLSSYPISSSKWSVGSAFRVPDTLRFSADSSNV 349
              G  R+ A P  +    P     F       P     W+ G  F VP   R    +S  
Sbjct: 1002 PRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPP--REVIKASPH 1059

Query: 350  VPSPLAGPLQPPFPQPPRYPLMLRNTLARSQSSPFLPNDVTLWN 393
             P P A    PP       PL L +T     + P LP   T+ N
Sbjct: 1060 APDPSAFSYAPP---GHPLPLGLHDT-----ARPVLPRPPTISN 1095


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 84/380 (22%), Positives = 132/380 (34%), Gaps = 71/380 (18%)

Query: 14   PVSQPPRAPLQRTPKCARCRNHG------VLSWLKGHKRYCRFKDCTCEKCILIIERQRV 67
            P  Q  +  +Q T  C R  N G      +++    H ++C+   C    C+ I  + ++
Sbjct: 1755 PSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNI--KHKL 1812

Query: 68   MAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAEL 127
               Q+  R QQA      +   + R +P    P    +AP   P  QPS PQ P+P    
Sbjct: 1813 RQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPT-SAPPGTPTQQPSTPQTPQP---- 1867

Query: 128  AAAAALRWTAEPQPGALQAQLAK-PDLTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKS 186
                     A+PQP  +    A  P +        ++   T V + K T Q  +P     
Sbjct: 1868 --------PAQPQPSPVSMSPAGFPSV-------ARTQPPTTVSTGKPTSQVPAPPPPAQ 1912

Query: 187  KGCFTPESPEIVSVE----EGGYAVQKNGGNPESRPDSPKCHAEQNHLLIEGPSGTVSLP 242
                  E+   +  E    +  Y V  N   P  R                G  G+   P
Sbjct: 1913 PPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGM-------------GTPGSQMAP 1959

Query: 243  FSLKANRPPLEVLKKIFPN-------QKPTVLELILKGCGGDLVSAVEVLLSSRSSVTGA 295
             SL   RP  +V   + P+       Q P   +  + G    ++S     + ++++V G 
Sbjct: 1960 VSLNVPRPN-QVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVIS-----MQAQAAVAGP 2013

Query: 296  ERTSAEPESLALPSNGHIFEHTLSS----------YPISSSKWSVGSAFRVPDTLRFSAD 345
               S +P     PS       TL S            I  S   + +AF    T ++ A+
Sbjct: 2014 RMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVAN 2073

Query: 346  SSNVVPSPLAGPLQPPFPQP 365
               + P P  G    P  QP
Sbjct: 2074 QPGMQPQP--GLQSQPGMQP 2091


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 84/380 (22%), Positives = 132/380 (34%), Gaps = 71/380 (18%)

Query: 14   PVSQPPRAPLQRTPKCARCRNHG------VLSWLKGHKRYCRFKDCTCEKCILIIERQRV 67
            P  Q  +  +Q T  C R  N G      +++    H ++C+   C    C+ I  + ++
Sbjct: 1793 PSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNI--KHKL 1850

Query: 68   MAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAEL 127
               Q+  R QQA      +   + R +P    P    +AP   P  QPS PQ P+P    
Sbjct: 1851 RQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPT-SAPPGTPTQQPSTPQTPQP---- 1905

Query: 128  AAAAALRWTAEPQPGALQAQLAK-PDLTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKS 186
                     A+PQP  +    A  P +        ++   T V + K T Q  +P     
Sbjct: 1906 --------PAQPQPSPVSMSPAGFPSV-------ARTQPPTTVSTGKPTSQVPAPPPPAQ 1950

Query: 187  KGCFTPESPEIVSVE----EGGYAVQKNGGNPESRPDSPKCHAEQNHLLIEGPSGTVSLP 242
                  E+   +  E    +  Y V  N   P  R                G  G+   P
Sbjct: 1951 PPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGM-------------GTPGSQMAP 1997

Query: 243  FSLKANRPPLEVLKKIFPN-------QKPTVLELILKGCGGDLVSAVEVLLSSRSSVTGA 295
             SL   RP  +V   + P+       Q P   +  + G    ++S     + ++++V G 
Sbjct: 1998 VSLNVPRPN-QVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVIS-----MQAQAAVAGP 2051

Query: 296  ERTSAEPESLALPSNGHIFEHTLSS----------YPISSSKWSVGSAFRVPDTLRFSAD 345
               S +P     PS       TL S            I  S   + +AF    T ++ A+
Sbjct: 2052 RMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVAN 2111

Query: 346  SSNVVPSPLAGPLQPPFPQP 365
               + P P  G    P  QP
Sbjct: 2112 QPGMQPQP--GLQSQPGMQP 2129


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 19/102 (18%)

Query: 63   ERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQ----- 117
            ER+ +  A +A     A     + +P      PG  PP  ++  PQP P+S P+Q     
Sbjct: 916  EREPLQTALLAFGVASATPGPAAPLPSPT---PGESPPASSL--PQPEPSSLPAQGVPTP 970

Query: 118  ---------PQPPRPAAELAAAAALRWTAEPQPGALQAQLAK 150
                     P PP P   L ++AA RW  E +P A  A L K
Sbjct: 971  LAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLK 1012


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 19/102 (18%)

Query: 63   ERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQ----- 117
            ER+ +  A +A     A     + +P      PG  PP  ++  PQP P+S P+Q     
Sbjct: 998  EREPLQTALLAFGVASATPGPAAPLPSPT---PGESPPASSL--PQPEPSSLPAQGVPTP 1052

Query: 118  ---------PQPPRPAAELAAAAALRWTAEPQPGALQAQLAK 150
                     P PP P   L ++AA RW  E +P A  A L K
Sbjct: 1053 LAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLK 1094


>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
          Length = 3664

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 17/35 (48%), Positives = 24/35 (68%)

Query: 93   ALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAEL 127
            A  GPPP G+ +  PQP  ++QP+QP PP P ++L
Sbjct: 3340 AAQGPPPEGEPLQPPQPVQSTQPAQPAPPCPPSQL 3374



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 74/343 (21%), Positives = 122/343 (35%), Gaps = 41/343 (11%)

Query: 95   PGPPP-PGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAEPQPGALQAQLAKPDL 153
            P PPP PG++    QPP  +Q  QP       + A +  L   A  +          P  
Sbjct: 2234 PAPPPYPGESQTDLQPPAGAQALQPSEEGMETDEAVSGILETEAATESSRPPVNAPDP-- 2291

Query: 154  TEERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKGCFTPESPEIVSVEEGGYAVQKNGGN 213
                     SA  T+    +     +S  V ++KG    E    V++       QK   +
Sbjct: 2292 ---------SAGPTDTKEARGNSSETSHSVPEAKGSKEVE----VTLVRKDKGRQKTTRS 2338

Query: 214  PESRPDSPKCHAE-QNHL----LIEGPSGTVSLPFSLKANRPPLEVLKKIFPNQKPTVLE 268
               R  + K  A  ++H+      +G S   +   +++    P E  +   P+  P    
Sbjct: 2339 RRKRNTNKKVVAPVESHVPESNQAQGESPAANEGTTVQHPEAPQEEKQSEKPHSTPP--- 2395

Query: 269  LILKGCGGDLVSAVEVLLSSRSSVTGAERT----SAEPESLALPSNGHIFEHTLSSYP-- 322
               + C  DL S +    +S   ++  ERT    S  P+    P    + E   + +   
Sbjct: 2396 ---QSCTSDL-SKIPSTENSSQEISVEERTPTKASVPPDLPPPPQPAPVDEEPQARFRVH 2451

Query: 323  --ISSSKWSVGSAFRVPDTLRFSADSSNVVPSPLAG--PLQPPFPQPPRYPLMLRNTLAR 378
              I S   +  S   +P     S  ++ + P   +G  P Q P  +   +        A+
Sbjct: 2452 SIIESDPVTPPSDPSIPIPTLPSVTAAKLSPPVASGGIPHQSPPTKVTEWITRQEEPRAQ 2511

Query: 379  SQSSPFLPNDVTLWNTMTLQ---QQYQLRSQYVSPFPSNSTSV 418
            S  SP LP D    +  T     ++  +  +YVS     STSV
Sbjct: 2512 STPSPALPPDTKASDVDTSSSTLRKILMDPKYVSATSVTSTSV 2554


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 37/141 (26%), Positives = 59/141 (41%), Gaps = 32/141 (22%)

Query: 14   PVSQPPRAPLQRTPKCARCRNHG------VLSWLKGHKRYCRFKDCTCEKCILIIER--- 64
            P  Q  +  +Q T  C R  N G      +++    H ++C+   C    C+ I ++   
Sbjct: 1756 PSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQ 1815

Query: 65   ----QRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQP 120
                 R+  AQ+ LRR+ A+     ++    + LP P P     A P  P   QP+ PQ 
Sbjct: 1816 QQLQHRLQQAQM-LRRRMASMQRTGVVGQQ-QGLPSPTP-----ATPTTPTGQQPTTPQT 1868

Query: 121  PRPAAELAAAAALRWTAEPQP 141
            P+P            T++PQP
Sbjct: 1869 PQP------------TSQPQP 1877



 Score = 33.1 bits (74), Expect = 0.56
 Identities = 36/127 (28%), Positives = 53/127 (41%), Gaps = 25/127 (19%)

Query: 94  LPGPP--PPGDAVAAPQPPPASQPSQP--------QPPRPAAELA-------------AA 130
           +P PP  PPG    A  PPP   P+ P        QP  PAA  A             AA
Sbjct: 863 VPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAA 922

Query: 131 AALRWTAEPQPGALQAQLAKPDLT-EERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKGC 189
           +    TA   P      L++P ++ E ++ +  S  +TEV S    +++ S +V K +  
Sbjct: 923 SVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEV-KMEAK 981

Query: 190 FTPESPE 196
              + PE
Sbjct: 982 MEVDQPE 988



 Score = 30.4 bits (67), Expect = 3.6
 Identities = 16/36 (44%), Positives = 18/36 (50%), Gaps = 3/36 (8%)

Query: 96   GPPPPGDA---VAAPQPPPASQPSQPQPPRPAAELA 128
            GP   G A   V  P PP  +QP  P PP  A E+A
Sbjct: 1894 GPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMA 1929



 Score = 30.4 bits (67), Expect = 3.6
 Identities = 19/61 (31%), Positives = 26/61 (42%), Gaps = 4/61 (6%)

Query: 87   IPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAEPQPGALQA 146
            IP+SL      P P  +      PP S PS    P+P+    +      T+ P PG + A
Sbjct: 2299 IPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQ----TSSPHPGLVAA 2354

Query: 147  Q 147
            Q
Sbjct: 2355 Q 2355



 Score = 29.3 bits (64), Expect = 8.1
 Identities = 44/180 (24%), Positives = 59/180 (32%), Gaps = 21/180 (11%)

Query: 95   PGPPPPGDAVAAPQPPPASQPSQPQP-------PRPAAELAAAAALRWTAEPQPGALQAQ 147
            PG  P G      Q PP SQ   PQP       PRPA    A         PQPG  Q  
Sbjct: 1982 PGMGPTG----MQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVG 2037

Query: 148  LAKPDLTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKGCFTPESPEIVSVEEGGYAV 207
            ++        L  G  +        +     SSP   +        +P++++      A 
Sbjct: 2038 ISP-------LKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAA 2090

Query: 208  QKNGGNPESRPDSPKCHAEQNHL---LIEGPSGTVSLPFSLKANRPPLEVLKKIFPNQKP 264
            +    NP+  P  P     Q  L    + G  G  S P     N     V +   P Q+P
Sbjct: 2091 KYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQP 2150


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 39/147 (26%), Positives = 58/147 (39%), Gaps = 15/147 (10%)

Query: 88  PDSLRALPGPPPPGDAVAAPQPPPA-SQPSQPQP--PRPAAELAAAAALRWTAEPQPGAL 144
           P+ + A   P P  +A  AP PPPA   PS P P  P+   E   AAA        P   
Sbjct: 787 PEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAA--------PPVE 838

Query: 145 QAQLAKPDLTEERLGD-GKSADNTEVFSDKDTDQRSSPDVAKSKGCFTPESPEIVSVEEG 203
           + +  KP   EE   D GK+ +  +    ++ ++  +          T E       +EG
Sbjct: 839 EGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEG 898

Query: 204 G---YAVQKNGGNPESRPDSPKCHAEQ 227
           G       K+ G P+    S  C A++
Sbjct: 899 GSGRATTAKSSGAPQDSDSSATCSADE 925



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 24/67 (35%), Positives = 28/67 (41%), Gaps = 8/67 (11%)

Query: 96  GPPPPGDAVA------APQPPPASQPSQPQPPRPAAELAAAAALRWTAEPQPGALQAQLA 149
           GP PP    A       P PPP   P+ P  P PA+E A  A     A P P A    + 
Sbjct: 766 GPKPPATLGADGPPPGPPTPPPEDIPA-PTEPTPASE-ATGAPTPPPAPPSPSAPPPVVP 823

Query: 150 KPDLTEE 156
           K +  EE
Sbjct: 824 KEEKEEE 830


>gi|32307177 forkhead box G1 [Homo sapiens]
          Length = 489

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/112 (27%), Positives = 39/112 (34%), Gaps = 20/112 (17%)

Query: 97  PPPPGDAVAAPQPPPASQPSQ--------------------PQPPRPAAELAAAAALRWT 136
           PPPP      P PPPA QP Q                    P PP PAA L  A A    
Sbjct: 66  PPPPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQLLLPPPPPPPPAAALDGAKADGLG 125

Query: 137 AEPQPGALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKG 188
            + +PG    +LA     E+  G G   +  +   +   D     +  K  G
Sbjct: 126 GKGEPGGGPGELAPVGPDEKEKGAGAGGEEKKGAGEGGKDGEGGKEGEKKNG 177



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 22/55 (40%), Positives = 23/55 (41%), Gaps = 5/55 (9%)

Query: 97  PPPPGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAEPQPGALQAQLAKP 151
           PPPP     APQPPP  Q  QP PP P A           A+   G  Q  L  P
Sbjct: 58  PPPP-----APQPPPPPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQLLLPPP 107


>gi|23503317 coiled-coil domain containing 96 [Homo sapiens]
          Length = 555

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 37/135 (27%), Positives = 54/135 (40%), Gaps = 11/135 (8%)

Query: 63  ERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPP-------ASQP 115
           E +   A+Q      +  E+ + L         GP  PG   A PQP P       A +P
Sbjct: 50  EEEEQAASQGGTAADEQAEAPKGLTAAEAAGEEGPGEPGRP-AEPQPEPEEPAEVGAEEP 108

Query: 116 SQPQPPRPAAELAAAAA---LRWTAEPQPGALQAQLAKPDLTEERLGDGKSADNTEVFSD 172
           +QP+P     EL A A    L   AE +    QA L    + EE       A+   V  +
Sbjct: 109 AQPEPGAGPEELEAEAGAEELEQAAEGKEVRFQASLPLTRIDEEEAAAAPEAETERVEGE 168

Query: 173 KDTDQRSSPDVAKSK 187
           ++  + +  D A+SK
Sbjct: 169 EEDKEETQRDGAESK 183


>gi|90903231 huntingtin [Homo sapiens]
          Length = 3144

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 4/72 (5%)

Query: 54  TCEKCILIIERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPAS 113
           T EK +   E  +    Q   ++QQ  +  +       +  P PPPP      PQPPP +
Sbjct: 3   TLEKLMKAFESLKSFQQQQQQQQQQQQQQQQQ--QQQQQQPPPPPPPPPPPQLPQPPPQA 60

Query: 114 QP--SQPQPPRP 123
           QP   QPQPP P
Sbjct: 61  QPLLPQPQPPPP 72



 Score = 32.7 bits (73), Expect = 0.73
 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 4/63 (6%)

Query: 63  ERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGD-AVAAPQPPPASQPSQPQPP 121
           ++Q+    Q   ++QQ  +      P     LP PPP     +  PQPPP   P  P PP
Sbjct: 22  QQQQQQQQQQQQQQQQQQQPPPPPPPPPPPQLPQPPPQAQPLLPQPQPPP---PPPPPPP 78

Query: 122 RPA 124
            PA
Sbjct: 79  GPA 81


>gi|122937289 kinesin family member 18B [Homo sapiens]
          Length = 855

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 14/109 (12%)

Query: 96  GPPPPGDAVAAPQ--PPPASQPSQPQPPRPAAELAAAAALRWTAEPQPGALQAQLAKPDL 153
           G PPP D   +P+  PPP   PS P PP P ++              P ALQ +    + 
Sbjct: 394 GQPPPQDLPGSPKSGPPPEHLPSSPLPPHPPSQPCTP-----ELPAGPRALQEESLGMEA 448

Query: 154 TEERLGDGKSADNTEVFSDKDTDQRSSPDV-----AKSKGCFTPESPEI 197
             ER  +G S+D  +  S +D D+  + +V      ++     PESP +
Sbjct: 449 QVERAMEGNSSDQEQ--SPEDEDEGPAEEVPTQMPEQNPTHALPESPRL 495


>gi|238859557 regulatory factor X1 [Homo sapiens]
          Length = 979

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 25/59 (42%), Positives = 30/59 (50%), Gaps = 3/59 (5%)

Query: 91  LRALPGP--PPPGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAEPQPGALQAQ 147
           L+A P P  PP     A PQPPP   P+ PQPP+P    AA    ++  E Q    QAQ
Sbjct: 9   LQAAPPPSQPPQAPPQAQPQPPPPPPPAAPQPPQPPT-AAATPQPQYVTELQSPQPQAQ 66



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 6/45 (13%)

Query: 88  PDSLRALPGPPPPGDAVAAPQPPPASQPSQP------QPPRPAAE 126
           P   +  P PPPP  A   PQPP A+   QP      Q P+P A+
Sbjct: 22  PPQAQPQPPPPPPPAAPQPPQPPTAAATPQPQYVTELQSPQPQAQ 66


>gi|47578107 delangin isoform B [Homo sapiens]
          Length = 2697

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 8/85 (9%)

Query: 145 QAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKGCFTPESPEIVSVEEGG 204
           ++ + +P   E RL D K  DN +     +T  +S P+  K KG   PE+P+  S     
Sbjct: 665 ESTIVEPKQNENRLSDTKPNDNKQNNGRSETT-KSRPETPKQKGESRPETPKQKSDGHPE 723

Query: 205 YAVQKNGGNP-------ESRPDSPK 222
              QK  G P       ESRP++PK
Sbjct: 724 TPKQKGDGRPETPKQKGESRPETPK 748


>gi|47578105 delangin isoform A [Homo sapiens]
          Length = 2804

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 8/85 (9%)

Query: 145 QAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKGCFTPESPEIVSVEEGG 204
           ++ + +P   E RL D K  DN +     +T  +S P+  K KG   PE+P+  S     
Sbjct: 665 ESTIVEPKQNENRLSDTKPNDNKQNNGRSETT-KSRPETPKQKGESRPETPKQKSDGHPE 723

Query: 205 YAVQKNGGNP-------ESRPDSPK 222
              QK  G P       ESRP++PK
Sbjct: 724 TPKQKGDGRPETPKQKGESRPETPK 748


>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
          Length = 1243

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 46/155 (29%), Positives = 69/155 (44%), Gaps = 18/155 (11%)

Query: 68   MAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAEL 127
            +A+  +L      +SL S  P  L   P P PP    + P PPP +   Q  P    AE+
Sbjct: 926  LASAFSLAVMTVAQSLLSPSPGLLSQSP-PAPPSPLPSLPLPPPVAPGGQESPSPHTAEV 984

Query: 128  AAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTD-----QRSSPD 182
             + A+    A P PG  +A+LA   ++EE  G  +     +V S K+       Q +SP 
Sbjct: 985  ESEASPP-PARPLPG--EARLA--PISEE--GKPQLVGRFQVTSSKEPAEPLPLQPTSPT 1037

Query: 183  VAKSKGCFTPESPEIVSVEEGGYAVQKNGGNPESR 217
            ++   G   P +P++ S  E        GG PE+R
Sbjct: 1038 LS---GSPKPSTPQLTS--ESSDTEDSAGGGPETR 1067



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 12/73 (16%)

Query: 90  SLRALPGPPPPGDA-VAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAEPQPGALQAQL 148
           SL A P P PP     A P P  +  PS  +PP             WT E  P       
Sbjct: 74  SLPASPAPDPPDPPDSAGPGPARSPPPSSKEPPEGT----------WT-EGAPVKAAEDS 122

Query: 149 AKPDLTEERLGDG 161
           A+P+L +  +G G
Sbjct: 123 ARPELPDSAVGPG 135



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 42/160 (26%), Positives = 55/160 (34%), Gaps = 52/160 (32%)

Query: 64  RQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRP 123
           R+RV A Q    + +    LE+L          PP PG       PPPA+ P  P PP  
Sbjct: 511 RERVAAIQRKREKLRKARELEAL----------PPEPG-------PPPATVPMAPGPPS- 552

Query: 124 AAELAAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSSPDV 183
                          P+P   +A   +P L        + A  +   SD +TD   S   
Sbjct: 553 ------------VFPPEPEEPEADQHQPFLF-------RHASYSSTTSDCETDGYLS--- 590

Query: 184 AKSKGCFTPESPEIVSVEEGGYAVQKNGGNPESRPDSPKC 223
             S G      P          A+Q  GG P S  +S  C
Sbjct: 591 --SSGFLDASDP----------ALQPPGGVPSSLAESHLC 618


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 38/136 (27%), Positives = 55/136 (40%), Gaps = 14/136 (10%)

Query: 96  GPPPPGDAVAAPQP---PPASQPSQPQPPRPAAELAAAAALRWTAEPQ---------PGA 143
           GP PPG A   P P   P A +P  P  P    +L AA A R TA P          PG 
Sbjct: 14  GPLPPGGAGPGPGPGPGPGAGKP--PSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGP 71

Query: 144 LQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKGCFTPESPEIVSVEEG 203
                ++    +E LG+ ++A  T   +   T    SP   +++G    E+       + 
Sbjct: 72  GPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQV 131

Query: 204 GYAVQKNGGNPESRPD 219
               Q++G +P   PD
Sbjct: 132 DSRTQRSGRSPSVSPD 147



 Score = 37.4 bits (85), Expect = 0.030
 Identities = 46/157 (29%), Positives = 67/157 (42%), Gaps = 19/157 (12%)

Query: 93  ALPGPP----PPGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAEPQPGALQAQL 148
           ++PGP     PP     +PQPP  ++PS  +P  PA E  A +A   TA P  G    + 
Sbjct: 286 SVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSA---TAVP-AGLGATEQ 341

Query: 149 AKPDLTEERLGDGKS---ADNTEVFSDKDTDQRSSPDVAKSKGCFTPESPEIVSVEEGGY 205
            +  LT +  G G S     +T +    + D +  P  A SKG     +P+IV  +    
Sbjct: 342 TQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQP--APSKG-----TPKIVFNDASKE 394

Query: 206 AVQKNGGNPESRPDSPKCHAEQNHLLIEGPSGTVSLP 242
           A  K  G+      +P    E    +  G SG  +LP
Sbjct: 395 AGPKPLGSGPGPGPAPGAKTEPGARMGPG-SGPGALP 430



 Score = 33.1 bits (74), Expect = 0.56
 Identities = 41/148 (27%), Positives = 51/148 (34%), Gaps = 16/148 (10%)

Query: 95   PGPPPPGDAVAAPQPPPASQPSQPQPP-----RPAAELAAAAALRWTAE---PQPGALQA 146
            P  P P    A   PP AS P++P  P     RP    A    +  T     P P   +A
Sbjct: 3081 PTYPGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRA 3140

Query: 147  QLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSSPD------VAKSKGCFTPESPEIVSV 200
             L KP  T     + K   N EV +       S+P        A S G    + PE+   
Sbjct: 3141 PLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRA 3200

Query: 201  EEGGYAVQKNGGNPESRPDSPKCHAEQN 228
             + G   Q     P    DS     EQN
Sbjct: 3201 GDRGSVSQSPA--PTYPSDSHYTSLEQN 3226


>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
          Length = 548

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 6/66 (9%)

Query: 88  PDSLRALPGPPPPGDAVAAPQP----PPASQPSQ--PQPPRPAAELAAAAALRWTAEPQP 141
           P  +  +P PPPP      P P    PP  Q  Q  P PP P++ +A++  L W     P
Sbjct: 472 PPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQRSLP 531

Query: 142 GALQAQ 147
            A  A+
Sbjct: 532 AAAMAR 537


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 31/100 (31%), Positives = 43/100 (43%), Gaps = 15/100 (15%)

Query: 97   PPPPGDAVAAPQPPPASQPSQPQPPRPAA----ELAAAAALRWTAEPQPGALQAQLAKPD 152
            PPPP  ++  P PPP+  P+ P PP P A    + + +   + +    PG       KP 
Sbjct: 918  PPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGG-----KKPP 972

Query: 153  LTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKGCFTP 192
             T +R    KS+   E        +R S D   SK  FTP
Sbjct: 973  PTPQRNSSIKSSSGAE----HPEPKRPSVDSLVSK--FTP 1006



 Score = 35.8 bits (81), Expect = 0.087
 Identities = 21/75 (28%), Positives = 29/75 (38%), Gaps = 16/75 (21%)

Query: 95  PGPPPPGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTA----------------E 138
           P PPPP      P PPP   P  P    P+A  AA   ++++                  
Sbjct: 627 PLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKP 686

Query: 139 PQPGALQAQLAKPDL 153
           P P  +Q+Q  KP +
Sbjct: 687 PTPPVMQSQSVKPQI 701



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 3/49 (6%)

Query: 95  PGPPPPGDAVAAPQPPPASQPSQPQ--PPRPAAELAAAAALRWTAEPQP 141
           P PP PG A+A  +P P + PS PQ   P P  ++     +   A P P
Sbjct: 716 PPPPTPGSAMAQLKPAPCA-PSLPQFSAPPPPLKIHQVQHITQVAPPTP 763



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 19/64 (29%), Positives = 25/64 (39%), Gaps = 11/64 (17%)

Query: 95  PGPPPPGDAVAAPQPPPASQPSQ-------PQPPRPAAELAAAAALRWTAEPQPGALQAQ 147
           P PP P      P PPP     Q       P P  P   +    A ++   P P A+++Q
Sbjct: 826 PSPPTP----PVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQ 881

Query: 148 LAKP 151
             KP
Sbjct: 882 PLKP 885



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 15/47 (31%), Positives = 18/47 (38%)

Query: 95  PGPPPPGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAEPQP 141
           P  PPP   + AP PP A        P P +    A  +   A P P
Sbjct: 760 PPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTP 806



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 3/69 (4%)

Query: 79  ANESLESLIPDSLRALPGPPPPGDAVAAPQPP-PASQ--PSQPQPPRPAAELAAAAALRW 135
           A  S +++ P   +A P  P P    A  QP  PAS   PS P PP P           +
Sbjct: 787 APTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSF 846

Query: 136 TAEPQPGAL 144
            A+P P  L
Sbjct: 847 CAKPPPSPL 855


>gi|27735129 hypothetical protein LOC148345 [Homo sapiens]
          Length = 656

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 36/112 (32%), Positives = 47/112 (41%), Gaps = 12/112 (10%)

Query: 85  SLIPDSLRALPGP-PPPGDAVAAPQP-PPASQPSQP------QPPRPAAELAAAAALRWT 136
           S++P  ++A  GP PPPG+A     P PPA+ PS+P       P RP   L    AL   
Sbjct: 284 SILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLP 343

Query: 137 AEPQPGALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKG 188
                 +      +P+  E  L  G S   TE       +Q    D AKS G
Sbjct: 344 VSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQ----DPAKSPG 391


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.130    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,511,998
Number of Sequences: 37866
Number of extensions: 1373972
Number of successful extensions: 20893
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 381
Number of HSP's successfully gapped in prelim test: 617
Number of HSP's that attempted gapping in prelim test: 11842
Number of HSP's gapped (non-prelim): 6533
length of query: 472
length of database: 18,247,518
effective HSP length: 106
effective length of query: 366
effective length of database: 14,233,722
effective search space: 5209542252
effective search space used: 5209542252
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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