Guide to the Human Genome
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Search of human proteins with 110349759

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110349759 NSL1, MIND kinetochore complex component isoform 1
[Homo sapiens]
         (281 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110349759 NSL1, MIND kinetochore complex component isoform 1 ...   571   e-163
gi|110349761 NSL1, MIND kinetochore complex component isoform 2 ...   338   4e-93
gi|95089461 discs large homolog 5 [Homo sapiens]                       35   0.056
gi|21040368 beta-site APP-cleaving enzyme 1 isoform D preproprot...    33   0.21 
gi|21040366 beta-site APP-cleaving enzyme 1 isoform B preproprot...    33   0.21 
gi|21040364 beta-site APP-cleaving enzyme 1 isoform C preproprot...    33   0.21 
gi|6912266 beta-site APP-cleaving enzyme 1 isoform A preproprote...    33   0.21 
gi|38524622 formin binding protein 1 [Homo sapiens]                    32   0.62 
gi|11560152 zinc finger protein 335 [Homo sapiens]                     32   0.62 
gi|223555917 metadherin [Homo sapiens]                                 31   1.1  
gi|93102364 SWAP-70 protein [Homo sapiens]                             31   1.4  
gi|239745983 PREDICTED: similar to Rho-associated, coiled-coil c...    30   1.8  
gi|8922461 transmembrane protein 38B [Homo sapiens]                    30   1.8  
gi|115647981 glutamine and serine rich 1 [Homo sapiens]                30   1.8  
gi|117968420 NUF2, NDC80 kinetochore complex component [Homo sap...    30   2.4  
gi|117968353 NUF2, NDC80 kinetochore complex component [Homo sap...    30   2.4  
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]    30   2.4  
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi...    30   2.4  
gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapi...    30   3.1  
gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapi...    30   3.1  
gi|21264320 NLR family, pyrin domain containing 6 [Homo sapiens]       30   3.1  
gi|28269672 serologically defined colon cancer antigen 8 [Homo s...    29   4.0  
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [...    29   5.3  
gi|115511012 coiled-coil domain containing 136 [Homo sapiens]          28   6.9  
gi|4885583 Rho-associated, coiled-coil containing protein kinase...    28   9.0  
gi|239752561 PREDICTED: similar to Rho-associated, coiled-coil c...    28   9.0  
gi|4759182 syntaxin 1A (brain) [Homo sapiens]                          28   9.0  
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    28   9.0  
gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens]      28   9.0  
gi|24308223 hypothetical protein LOC57577 [Homo sapiens]               28   9.0  

>gi|110349759 NSL1, MIND kinetochore complex component isoform 1
           [Homo sapiens]
          Length = 281

 Score =  571 bits (1471), Expect = e-163
 Identities = 281/281 (100%), Positives = 281/281 (100%)

Query: 1   MAGSPELVVLDPPWDKELAAGTESQALVSATPREDFRVRCTSKRAVTEMLQLCGRFVQKL 60
           MAGSPELVVLDPPWDKELAAGTESQALVSATPREDFRVRCTSKRAVTEMLQLCGRFVQKL
Sbjct: 1   MAGSPELVVLDPPWDKELAAGTESQALVSATPREDFRVRCTSKRAVTEMLQLCGRFVQKL 60

Query: 61  GDALPEEIREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIV 120
           GDALPEEIREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIV
Sbjct: 61  GDALPEEIREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIV 120

Query: 121 DIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPAPHMENLKCRGETV 180
           DIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPAPHMENLKCRGETV
Sbjct: 121 DIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPAPHMENLKCRGETV 180

Query: 181 AKEISEAMKSLPALIEQGEGFSQVLRMQPVIHLQRIHQEVFSSCHRKPDAKPENFITQIE 240
           AKEISEAMKSLPALIEQGEGFSQVLRMQPVIHLQRIHQEVFSSCHRKPDAKPENFITQIE
Sbjct: 181 AKEISEAMKSLPALIEQGEGFSQVLRMQPVIHLQRIHQEVFSSCHRKPDAKPENFITQIE 240

Query: 241 TTPTETASRKTSDMVLKRKQTKDCPQRKWYPLRPKKINLDT 281
           TTPTETASRKTSDMVLKRKQTKDCPQRKWYPLRPKKINLDT
Sbjct: 241 TTPTETASRKTSDMVLKRKQTKDCPQRKWYPLRPKKINLDT 281


>gi|110349761 NSL1, MIND kinetochore complex component isoform 2
           [Homo sapiens]
          Length = 213

 Score =  338 bits (866), Expect = 4e-93
 Identities = 166/166 (100%), Positives = 166/166 (100%)

Query: 1   MAGSPELVVLDPPWDKELAAGTESQALVSATPREDFRVRCTSKRAVTEMLQLCGRFVQKL 60
           MAGSPELVVLDPPWDKELAAGTESQALVSATPREDFRVRCTSKRAVTEMLQLCGRFVQKL
Sbjct: 1   MAGSPELVVLDPPWDKELAAGTESQALVSATPREDFRVRCTSKRAVTEMLQLCGRFVQKL 60

Query: 61  GDALPEEIREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIV 120
           GDALPEEIREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIV
Sbjct: 61  GDALPEEIREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIV 120

Query: 121 DIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDP 166
           DIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDP
Sbjct: 121 DIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDP 166


>gi|95089461 discs large homolog 5 [Homo sapiens]
          Length = 1919

 Score = 35.4 bits (80), Expect = 0.056
 Identities = 44/181 (24%), Positives = 81/181 (44%), Gaps = 13/181 (7%)

Query: 91  NGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPR-----KILECVIKTIKAKQ 145
           NGQ  +E +       D+K L ++  + I D+  +++Q  +     +IL  +  T   K 
Sbjct: 251 NGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKL 310

Query: 146 EILKQYHPVVHPLDLKYDPDPAPHMENLKCRGETVAKEISEAMKSLPALIEQGEGFSQVL 205
           E++K+ +  +     +Y    A H  +L  R E + +E    +K    L +Q +   Q L
Sbjct: 311 EVVKKDYDALRK---RYSEKVAIHNADLS-RLEQLGEENQRLLKQTEMLTQQRDTAIQ-L 365

Query: 206 RMQPVIHLQR---IHQEVFSSCHRKPDAKPENFITQIETTPTETASRKTSDMVLKRKQTK 262
           + Q  + L+R   IH E+  +  +  D + E  + Q E T   T   KT+    K ++ +
Sbjct: 366 QHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREER 425

Query: 263 D 263
           D
Sbjct: 426 D 426


>gi|21040368 beta-site APP-cleaving enzyme 1 isoform D preproprotein
           [Homo sapiens]
          Length = 432

 Score = 33.5 bits (75), Expect = 0.21
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 12/67 (17%)

Query: 77  QWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILEC 136
           +W +E  +   + INGQ           D  +   E  +D+ IVD  T   + P+K+ E 
Sbjct: 188 EWYYEVIIVR-VEINGQ-----------DLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEA 235

Query: 137 VIKTIKA 143
            +K+IKA
Sbjct: 236 AVKSIKA 242


>gi|21040366 beta-site APP-cleaving enzyme 1 isoform B preproprotein
           [Homo sapiens]
          Length = 476

 Score = 33.5 bits (75), Expect = 0.21
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 12/67 (17%)

Query: 77  QWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILEC 136
           +W +E  +   + INGQ           D  +   E  +D+ IVD  T   + P+K+ E 
Sbjct: 232 EWYYEVIIVR-VEINGQ-----------DLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEA 279

Query: 137 VIKTIKA 143
            +K+IKA
Sbjct: 280 AVKSIKA 286


>gi|21040364 beta-site APP-cleaving enzyme 1 isoform C preproprotein
           [Homo sapiens]
          Length = 457

 Score = 33.5 bits (75), Expect = 0.21
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 12/67 (17%)

Query: 77  QWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILEC 136
           +W +E  +   + INGQ           D  +   E  +D+ IVD  T   + P+K+ E 
Sbjct: 213 EWYYEVIIVR-VEINGQ-----------DLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEA 260

Query: 137 VIKTIKA 143
            +K+IKA
Sbjct: 261 AVKSIKA 267


>gi|6912266 beta-site APP-cleaving enzyme 1 isoform A preproprotein
           [Homo sapiens]
          Length = 501

 Score = 33.5 bits (75), Expect = 0.21
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 12/67 (17%)

Query: 77  QWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILEC 136
           +W +E  +   + INGQ           D  +   E  +D+ IVD  T   + P+K+ E 
Sbjct: 257 EWYYEVIIVR-VEINGQ-----------DLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEA 304

Query: 137 VIKTIKA 143
            +K+IKA
Sbjct: 305 AVKSIKA 311


>gi|38524622 formin binding protein 1 [Homo sapiens]
          Length = 617

 Score = 32.0 bits (71), Expect = 0.62
 Identities = 33/113 (29%), Positives = 46/113 (40%), Gaps = 13/113 (11%)

Query: 111 LEDQFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPAPHM 170
           L DQFD +      K  Q+   ILE  IK +K + EI   Y   +  L  KY P      
Sbjct: 7   LWDQFDNL-----EKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQP-----K 56

Query: 171 ENLKCRGE---TVAKEISEAMKSLPALIEQGEGFSQVLRMQPVIHLQRIHQEV 220
           +N K   E   T  K     +  +     Q E  S+ +  Q ++ L R  QE+
Sbjct: 57  KNSKEEEEYKYTSCKAFISNLNEMNDYAGQHEVISENMASQIIVDLARYVQEL 109


>gi|11560152 zinc finger protein 335 [Homo sapiens]
          Length = 1342

 Score = 32.0 bits (71), Expect = 0.62
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 14/103 (13%)

Query: 130 PRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPAPHMENLKC----RGETVAKEIS 185
           P K  EC   ++  K  I    H  VH  D K  PDP P + +  C    R   + K ++
Sbjct: 522 PYKCDECSYTSVYRKDVIR---HAAVHSRDRKKRPDPTPKLSSFPCPVCGRVYPMQKRLT 578

Query: 186 EAMKS----LPALIEQ-GEGFSQ--VLRMQPVIHLQRIHQEVF 221
           + MK+     P + ++ G+ F +    +M  + H+Q +    F
Sbjct: 579 QHMKTHSTEKPHMCDKCGKSFKKRYTFKMHLLTHIQAVANRRF 621


>gi|223555917 metadherin [Homo sapiens]
          Length = 582

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 2/56 (3%)

Query: 75  DAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYP 130
           D+     S + EN+++NG  W E S    + S I   E++++ +    A KRK  P
Sbjct: 266 DSTLQVSSGLNENLTVNGGGWNEKSVK--LSSQISAGEEKWNSVSPASAGKRKTEP 319


>gi|93102364 SWAP-70 protein [Homo sapiens]
          Length = 585

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 35/150 (23%), Positives = 62/150 (41%), Gaps = 34/150 (22%)

Query: 111 LEDQFDEIIVDIATKRKQYPRK-------ILECVIKTI-------KAKQEILKQYHPVVH 156
           L+D+  +I++D     +  P K       +++C  KT        K KQE ++  H  +H
Sbjct: 247 LKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKKKQEWIQAIHSTIH 306

Query: 157 PLDLKYDPDPAPHMENLKCRGETVAKEISE------AMKSLPALIEQGEGFSQVLRMQPV 210
            L L     P PH E  + R E   K+++E       MK L A  E  +           
Sbjct: 307 LLKL---GSPPPHKEARQRRKELRKKQLAEQEELERQMKELQAANESKQQ---------- 353

Query: 211 IHLQRIHQEVFSSCHRKPDAKPENFITQIE 240
             L+ + +++  +  R  + + +   TQ+E
Sbjct: 354 -ELEAVRKKLEEAASRAAEEEKKRLQTQVE 382


>gi|239745983 PREDICTED: similar to Rho-associated, coiled-coil
           containing protein kinase 1 [Homo sapiens]
          Length = 118

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 16/63 (25%), Positives = 29/63 (46%)

Query: 130 PRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPAPHMENLKCRGETVAKEISEAMK 189
           P   LEC  + +K  ++ L +   ++ P  + YD   A  M  L C  +   K ++  +K
Sbjct: 44  PPPALECQRRHVKCHRDHLDKKEDLICPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVK 103

Query: 190 SLP 192
            +P
Sbjct: 104 KIP 106


>gi|8922461 transmembrane protein 38B [Homo sapiens]
          Length = 291

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 6/46 (13%)

Query: 218 QEVFSSCHRKPDAK-PENFITQIETTPTETASRKTSDMVLKRKQTK 262
           Q+ FSSC +K +AK P N +  + + P + AS       +K+K TK
Sbjct: 248 QQPFSSCEKKSEAKSPSNGVGSLASKPVDVASDN-----VKKKHTK 288


>gi|115647981 glutamine and serine rich 1 [Homo sapiens]
          Length = 1735

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 18/58 (31%), Positives = 27/58 (46%), Gaps = 2/58 (3%)

Query: 218  QEVFSSCHRKPDAKPENFITQIETTPTETASRKTSDMVLKRKQTKDCPQRKWYPLRPK 275
            +E    C +KP  KP   I  ++  P  ++S KTSD +  +  T   P  K    +PK
Sbjct: 1436 KEYVRVCSKKPRNKPSQTIRTVQAKP--SSSSKTSDPLASKTTTTKAPSVKPKVKQPK 1491


>gi|117968420 NUF2, NDC80 kinetochore complex component [Homo
           sapiens]
          Length = 464

 Score = 30.0 bits (66), Expect = 2.4
 Identities = 14/44 (31%), Positives = 25/44 (56%)

Query: 108 IKVLEDQFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQY 151
           +K +++     IVD   K K Y  K+ + V K   A+QE++++Y
Sbjct: 233 LKEIQESLKTKIVDSPEKLKNYKEKMKDTVQKLKNARQEVVEKY 276


>gi|117968353 NUF2, NDC80 kinetochore complex component [Homo
           sapiens]
          Length = 464

 Score = 30.0 bits (66), Expect = 2.4
 Identities = 14/44 (31%), Positives = 25/44 (56%)

Query: 108 IKVLEDQFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQY 151
           +K +++     IVD   K K Y  K+ + V K   A+QE++++Y
Sbjct: 233 LKEIQESLKTKIVDSPEKLKNYKEKMKDTVQKLKNARQEVVEKY 276


>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
          Length = 936

 Score = 30.0 bits (66), Expect = 2.4
 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 6/106 (5%)

Query: 68  IREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQ--FDEIIVDIATK 125
           I E  + D+++  E A   +I  N Q     + N + D D+K  E++  F E+++  +  
Sbjct: 141 ILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNFLELVLRKSLD 200

Query: 126 RKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPAPHME 171
           R++     L  VI T   K E+      +++ LD     D AP  +
Sbjct: 201 REETQEHRL-LVIATDGGKPELTGTVQLLINVLDAN---DNAPEFD 242


>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 816

 Score = 30.0 bits (66), Expect = 2.4
 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 6/106 (5%)

Query: 68  IREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQ--FDEIIVDIATK 125
           I E  + D+++  E A   +I  N Q     + N + D D+K  E++  F E+++  +  
Sbjct: 141 ILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNFLELVLRKSLD 200

Query: 126 RKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPAPHME 171
           R++     L  VI T   K E+      +++ LD     D AP  +
Sbjct: 201 REETQEHRL-LVIATDGGKPELTGTVQLLINVLDAN---DNAPEFD 242


>gi|71834863 Rho GTPase activating protein 5 isoform a [Homo
           sapiens]
          Length = 1502

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 9/73 (12%)

Query: 92  GQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQY 151
           GQ W+E    CF      V+ED+  + I + A  ++ Y R   E V K  +  QE+L ++
Sbjct: 447 GQPWEEVM--CF------VMEDEAYKYITE-ADSKEVYGRHQREIVEKAKEEFQEMLFEH 497

Query: 152 HPVVHPLDLKYDP 164
             + + LDL   P
Sbjct: 498 SELFYDLDLNATP 510


>gi|71834861 Rho GTPase activating protein 5 isoform b [Homo
           sapiens]
          Length = 1501

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 9/73 (12%)

Query: 92  GQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQY 151
           GQ W+E    CF      V+ED+  + I + A  ++ Y R   E V K  +  QE+L ++
Sbjct: 447 GQPWEEVM--CF------VMEDEAYKYITE-ADSKEVYGRHQREIVEKAKEEFQEMLFEH 497

Query: 152 HPVVHPLDLKYDP 164
             + + LDL   P
Sbjct: 498 SELFYDLDLNATP 510


>gi|21264320 NLR family, pyrin domain containing 6 [Homo sapiens]
          Length = 892

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 25/85 (29%), Positives = 44/85 (51%), Gaps = 6/85 (7%)

Query: 119 IVDIATKRKQYPRKILECVIKTIKAKQEILKQYHP-VVHPLDLKYDPDPAPHMENLK--- 174
           +V    K+K+   K L+  +    + Q   KQ    ++HPL  +   DP  H+ +L    
Sbjct: 679 LVAAQEKKKKSLGKRLQASLGGGSSSQGTTKQLPASLLHPL-FQAMTDPLCHLSSLTLSH 737

Query: 175 CR-GETVAKEISEAMKSLPALIEQG 198
           C+  + V +++SEA+++ PAL E G
Sbjct: 738 CKLPDAVCRDLSEALRAAPALTELG 762


>gi|28269672 serologically defined colon cancer antigen 8 [Homo
           sapiens]
          Length = 713

 Score = 29.3 bits (64), Expect = 4.0
 Identities = 23/116 (19%), Positives = 53/116 (45%), Gaps = 13/116 (11%)

Query: 94  AWQEASDNCFMDSDIKVLEDQFD-EIIVDIATKRKQYPRKILECVIKTIKAKQEILKQYH 152
           AW E   +  ++    +L  Q D E  V  + +RK  P       +++++ ++  +   H
Sbjct: 64  AWPELQQSHAVNQLKDLLRQQADKESEVSPSRRRKMSP-------LRSLEHEETNMPTMH 116

Query: 153 PVVHPLDLKYDPDPAPHMENLKCRGETVAKEISEAMKSLPALIEQGEGFSQVLRMQ 208
            +VH ++     D + ++ +L+   +   +E+S     +  ++ + EG  Q L+ Q
Sbjct: 117 DLVHTIN-----DQSQYIHHLEAEVKFCKEELSGMKNKIQVVVLENEGLQQQLKSQ 167


>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
            sapiens]
          Length = 1584

 Score = 28.9 bits (63), Expect = 5.3
 Identities = 19/88 (21%), Positives = 39/88 (44%), Gaps = 22/88 (25%)

Query: 205  LRMQPVIHLQRIHQEVFSSCHRK-------------PDAKPENFITQIETTPTETASRKT 251
            L  + ++H ++ HQ++F   +RK             PD+KPE           +T +++ 
Sbjct: 1480 LDFEKIMHTRKRHQDMFQDLNRKLQHAAEKDKEVLGPDSKPEK---------QQTPNKRP 1530

Query: 252  SDMVLKRKQTKDCPQRKWYPLRPKKINL 279
             + + K   T    +++  PL+P  + L
Sbjct: 1531 WESLRKAHGTPTWVKKELEPLQPSPLEL 1558


>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
          Length = 1154

 Score = 28.5 bits (62), Expect = 6.9
 Identities = 16/74 (21%), Positives = 38/74 (51%), Gaps = 1/74 (1%)

Query: 135 ECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPAPHMENLKCRGETVAKEISEAMKSLPAL 194
           +CV+K      E L+++    H  ++  +PD +   ++ KC     +K + E M++L  +
Sbjct: 633 DCVLKEQLEIHEELRRFKES-HFQEVLENPDDSKLAKSSKCNRNKQSKLLMEQMQALQVM 691

Query: 195 IEQGEGFSQVLRMQ 208
            + G+   ++L+ +
Sbjct: 692 YDAGQAKQELLQQE 705


>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
            [Homo sapiens]
          Length = 1354

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 16/63 (25%), Positives = 28/63 (44%)

Query: 130  PRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPAPHMENLKCRGETVAKEISEAMK 189
            P   LEC    +K  ++ L +   ++ P  + YD   A  M  L C  +   K ++  +K
Sbjct: 1255 PPPALECRRCHVKCHRDHLDKKEDLICPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVK 1314

Query: 190  SLP 192
             +P
Sbjct: 1315 KIP 1317


>gi|239752561 PREDICTED: similar to Rho-associated, coiled-coil
           containing protein kinase 1 [Homo sapiens]
          Length = 143

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 16/63 (25%), Positives = 28/63 (44%)

Query: 130 PRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPAPHMENLKCRGETVAKEISEAMK 189
           P   LEC    +K  ++ L +   ++ P  + YD   A  M  L C  +   K ++  +K
Sbjct: 44  PPPALECRRCHVKCHRDHLDKKEDLICPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVK 103

Query: 190 SLP 192
            +P
Sbjct: 104 KIP 106


>gi|4759182 syntaxin 1A (brain) [Homo sapiens]
          Length = 288

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 39/164 (23%), Positives = 63/164 (38%), Gaps = 16/164 (9%)

Query: 107 DIKVLEDQFDEIIVDIATKRKQYPRKILECV------IKTIKAKQEILKQYHPVVHPLDL 160
           +++  +D  D+  V +   R ++  +  E V      I  I    E +K+ H  +     
Sbjct: 7   ELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASP- 65

Query: 161 KYDPDPAPHMENLKCRGETVAKEISEAMKSLPALIEQGEGF---SQVLRMQPVIH--LQR 215
             D      +E L    +  A ++   +KS+   IEQ EG    S  LR++   H  L R
Sbjct: 66  NPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSR 125

Query: 216 IHQEVFSSCHRKPDAKPE----NFITQIETTPTETASRKTSDMV 255
              EV S  +       E        Q+E T   T S +  DM+
Sbjct: 126 KFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDML 169


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 36/154 (23%), Positives = 63/154 (40%), Gaps = 13/154 (8%)

Query: 57   VQKLGDALPEEIREP--ALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQ 114
            V++    L EE+ E   AL   + T   + QE +  + +     S N  + +  K LE  
Sbjct: 1678 VERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLE-- 1735

Query: 115  FDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPAPHMENLK 174
                  DIA  + +    I E      KAK+ I       +   +LK + D + H+E +K
Sbjct: 1736 -----ADIAQCQAEVENSIQESRNAEEKAKKAITDA---AMMAEELKKEQDTSAHLERMK 1787

Query: 175  CRGETVAKEISEAMKSLPALIEQGEGFSQVLRMQ 208
               E   K++   +     L  +G G  Q+ +++
Sbjct: 1788 KNLEQTVKDLQHRLDEAEQLALKG-GKKQIQKLE 1820


>gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens]
          Length = 822

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 15/59 (25%), Positives = 28/59 (47%)

Query: 141 IKAKQEILKQYHPVVHPLDLKYDPDPAPHMENLKCRGETVAKEISEAMKSLPALIEQGE 199
           IK KQ++ K Y  V   ++ +        +E LKC    + KE++ A +     + +G+
Sbjct: 104 IKDKQQVKKSYIGVHQQIEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGK 162


>gi|24308223 hypothetical protein LOC57577 [Homo sapiens]
          Length = 936

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 16/49 (32%), Positives = 24/49 (48%)

Query: 114 QFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKY 162
           Q   I+ D     K+  RK+ E +I+T K  Q+  K+Y    H L L +
Sbjct: 292 QSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDH 340


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,283,740
Number of Sequences: 37866
Number of extensions: 485872
Number of successful extensions: 1348
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1334
Number of HSP's gapped (non-prelim): 31
length of query: 281
length of database: 18,247,518
effective HSP length: 101
effective length of query: 180
effective length of database: 14,423,052
effective search space: 2596149360
effective search space used: 2596149360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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