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Search of human proteins with 15618995
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15618995 keratin 71 [Homo sapiens]
(523 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15618995 keratin 71 [Homo sapiens] 1014 0.0
gi|28173564 keratin 73 [Homo sapiens] 836 0.0
gi|148612803 keratin 6 irs4 [Homo sapiens] 722 0.0
gi|28372503 keratin 72 isoform 1 [Homo sapiens] 701 0.0
gi|226246663 keratin 72 isoform 1 [Homo sapiens] 701 0.0
gi|5031839 keratin 6A [Homo sapiens] 568 e-162
gi|119703753 keratin 6B [Homo sapiens] 568 e-162
gi|119395754 keratin 5 [Homo sapiens] 566 e-161
gi|155969697 keratin 6C [Homo sapiens] 565 e-161
gi|226246665 keratin 72 isoform 2 [Homo sapiens] 563 e-160
gi|109255249 keratin 4 [Homo sapiens] 563 e-160
gi|153791158 keratin 75 [Homo sapiens] 563 e-160
gi|119395750 keratin 1 [Homo sapiens] 559 e-159
gi|153791670 keratin 76 [Homo sapiens] 557 e-159
gi|109148552 keratin 3 [Homo sapiens] 553 e-157
gi|47132620 keratin 2 [Homo sapiens] 539 e-153
gi|194018511 keratin 77 [Homo sapiens] 536 e-152
gi|32567786 keratin 6L [Homo sapiens] 535 e-152
gi|67782365 keratin 7 [Homo sapiens] 459 e-129
gi|89357932 keratin 5b [Homo sapiens] 457 e-128
gi|4504919 keratin 8 [Homo sapiens] 446 e-125
gi|15431316 keratin, hair, basic, 4 [Homo sapiens] 440 e-123
gi|4504935 keratin 85 [Homo sapiens] 416 e-116
gi|27477127 keratin 82 [Homo sapiens] 415 e-116
gi|169790853 keratin, hair, basic, 1 [Homo sapiens] 402 e-112
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap... 402 e-112
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap... 402 e-112
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap... 402 e-112
gi|14318422 keratin 86 [Homo sapiens] 402 e-112
gi|169790841 keratin 83 [Homo sapiens] 399 e-111
>gi|15618995 keratin 71 [Homo sapiens]
Length = 523
Score = 1014 bits (2622), Expect = 0.0
Identities = 523/523 (100%), Positives = 523/523 (100%)
Query: 1 MSRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVA 60
MSRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVA
Sbjct: 1 MSRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVA 60
Query: 61 SGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELD 120
SGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELD
Sbjct: 61 SGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELD 120
Query: 121 PEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPI 180
PEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPI
Sbjct: 121 PEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPI 180
Query: 181 LEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKD 240
LEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKD
Sbjct: 181 LEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKD 240
Query: 241 VDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSI 300
VDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSI
Sbjct: 241 VDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSI 300
Query: 301 IDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRS 360
IDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRS
Sbjct: 301 IDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRS 360
Query: 361 EIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMS 420
EIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMS
Sbjct: 361 EIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMS 420
Query: 421 LKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGSVYGFRPSMVSGGYVANS 480
LKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGSVYGFRPSMVSGGYVANS
Sbjct: 421 LKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGSVYGFRPSMVSGGYVANS 480
Query: 481 SNCISGVCSVRGGEGRSRGSANDYKDTLGKGSSLSAPSKKTSR 523
SNCISGVCSVRGGEGRSRGSANDYKDTLGKGSSLSAPSKKTSR
Sbjct: 481 SNCISGVCSVRGGEGRSRGSANDYKDTLGKGSSLSAPSKKTSR 523
>gi|28173564 keratin 73 [Homo sapiens]
Length = 540
Score = 836 bits (2159), Expect = 0.0
Identities = 439/541 (81%), Positives = 480/541 (88%), Gaps = 19/541 (3%)
Query: 1 MSRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSL--N 58
MSRQFT KSGAAAKGGFSGCSAVLSGGSSSS+RAG KGLSGGF SRSLYSLGG RS+ N
Sbjct: 1 MSRQFTYKSGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFN 60
Query: 59 VASGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVE 118
VASGSG +GGYGFGRGRASGFAGSMFGSVALG VCP++CPPGGIHQVT+N+SLLAPLNVE
Sbjct: 61 VASGSGWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVE 120
Query: 119 LDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLE 178
LDPEIQKVRAQEREQIK LNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLE
Sbjct: 121 LDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLE 180
Query: 179 PILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLK 238
PILEGYISNLRKQLETLSGDRVRLDSELR+VR+VVEDYKKRYEEEINKRT AENEFV+LK
Sbjct: 181 PILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLK 240
Query: 239 KDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLD 298
KDVDAAY +KVELQAKV+++D EIKFF+CL+E E QIQSHISD S+ILSMDNNRNLDLD
Sbjct: 241 KDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLD 300
Query: 299 SIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRI 358
SII EVR QYEEIA KSKAEAEALYQTKFQELQLAAGRHGDDLK+TKNEISELTRLIQR+
Sbjct: 301 SIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRL 360
Query: 359 RSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQEL 418
RSEIE+VKKQ +NLETAIADAEQRGD ALKDARAKLDELEGAL QAKEELARMLREYQEL
Sbjct: 361 RSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQEL 420
Query: 419 MSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGG-------------SVY 465
+S+KL+LD+EIATYRKLLE EECRMSGE+ + VSIS+I+S+ G Y
Sbjct: 421 LSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTY 480
Query: 466 GFRPSMVSGGYVANSSNCI--SGVCSVRGGEGRSR-GSANDYKDTLGKGSSLSAPSKKTS 522
G+ PS VSGGY C+ SG CS R GE R+R GSA++++D+ GK +LS+P+KKT
Sbjct: 481 GYWPSSVSGGYSMLPGGCVTGSGNCSPR-GEARTRLGSASEFRDSQGKTLALSSPTKKTM 539
Query: 523 R 523
R
Sbjct: 540 R 540
>gi|148612803 keratin 6 irs4 [Homo sapiens]
Length = 529
Score = 722 bits (1863), Expect = 0.0
Identities = 393/534 (73%), Positives = 437/534 (81%), Gaps = 16/534 (2%)
Query: 1 MSRQFTCKSGAAAKGGFSGCSAVL---SGGSSSSFRAGSKGLSGGFGSRSLYSLGGVR-- 55
MSRQ KS + KG FS SAV+ + GS +S+ A +G GFGSRSLYSLGG R
Sbjct: 1 MSRQLNIKS-SGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRI 59
Query: 56 SLNVASGSGKSGGYGF------GRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNE 109
S NVA G ++GGYGF G GRASGFAGSMFGSVALGP C +VCPPGGIHQVTVN+
Sbjct: 60 SFNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNK 119
Query: 110 SLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLD 169
SLLAPLNVELDPEIQKVRAQEREQIK LN+KFASFIDKVRFLEQQNQVLETKWELLQQLD
Sbjct: 120 SLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLD 179
Query: 170 LNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTA 229
LNNCK NLEPILEGYISNLRKQLETLSGDRVRLDSELR++RD+VEDYKKRYE EIN+RT
Sbjct: 180 LNNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTT 239
Query: 230 AENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSM 289
AENEFV+LKKD DAAYA KVELQAKV+S+D+EIKF +CL++AEI QIQ+H S+ SVILSM
Sbjct: 240 AENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSM 299
Query: 290 DNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEIS 349
DNNR+LDLDSII EVR YEEIALKSKAEAEALYQTK QELQLAA RHGDDLK+T++E+
Sbjct: 300 DNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMV 359
Query: 350 ELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELA 409
EL RLIQRIR EI NVKKQ ++LETAIADAEQRGDNALKDA+AKLDELEGALHQAKEELA
Sbjct: 360 ELNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELA 419
Query: 410 RMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGSVYGFRP 469
RMLREYQELMSLKLALDMEIATYRKLLE EECRMSGE PS VSIS+ISS+S Y +
Sbjct: 420 RMLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSS----YSYHH 475
Query: 470 SMVSGGYVANSSNCISGVCSVRGGEGRSRGSANDYKDTLGKGSSLSAPSKKTSR 523
+G + S+ S + G + D KDT GK + S P++K +R
Sbjct: 476 PSSAGVDLGASAVAGSSGSTQSGQTKTTEARGGDLKDTQGKSTPASIPARKATR 529
>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 701 bits (1808), Expect = 0.0
Identities = 386/528 (73%), Positives = 432/528 (81%), Gaps = 22/528 (4%)
Query: 1 MSRQFTCKSGAAAKGGFSGCSAVLSGG---SSSSFRAGSKGLSGGFGSRSLYSLGGVRSL 57
MSRQ T + GFSGCSAVLSGG SS+SFRA KG S FGS+SL LGG RSL
Sbjct: 1 MSRQLT-HFPRGERLGFSGCSAVLSGGIGSSSASFRARVKG-SASFGSKSLSCLGGSRSL 58
Query: 58 NVASGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNV 117
+++ + + GG R GF G+ FGS LGP CP+VCPPGGI QVTVN+SLLAPLNV
Sbjct: 59 ALSAAARRGGG------RLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNV 112
Query: 118 ELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNL 177
E+DPEIQ+VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKW LLQQLDLNNC+ NL
Sbjct: 113 EMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNL 172
Query: 178 EPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLL 237
EPI EGYISNL+KQLE LSGD VRLDSELRN++D+VEDYKKRYE EIN+RTAAENEFV+L
Sbjct: 173 EPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVL 232
Query: 238 KKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDL 297
KKDVDAAY NKVELQAKV+S+ EIKFF+CL+E EITQIQSHISD S++LSMDNNR+LDL
Sbjct: 233 KKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDL 292
Query: 298 DSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQR 357
DSII EVR QYEEIALKSKAEAE LYQTK QELQ+ AG+HGDDLK TK EISEL RLIQR
Sbjct: 293 DSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQR 352
Query: 358 IRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQE 417
IRSEI NVKKQ ++LETAIADAEQRGD ALKDARAKLDELEGALHQAKEELARMLREYQE
Sbjct: 353 IRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQE 412
Query: 418 LMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGS-VYGFRPSMVSGGY 476
L+SLKLALDMEIATYRKLLESEECRMSGE+P+ VSIS+ISST+ G+ GF S G+
Sbjct: 413 LVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGF-----SMGF 467
Query: 477 VANSSNCISGVCSVRGGEGRSRGS-ANDYKDTLGKGSSLSAPSKKTSR 523
A+SS + +++GS ++ KD L K S S +KK SR
Sbjct: 468 GASSSYSY----KTAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR 511
>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 701 bits (1808), Expect = 0.0
Identities = 386/528 (73%), Positives = 432/528 (81%), Gaps = 22/528 (4%)
Query: 1 MSRQFTCKSGAAAKGGFSGCSAVLSGG---SSSSFRAGSKGLSGGFGSRSLYSLGGVRSL 57
MSRQ T + GFSGCSAVLSGG SS+SFRA KG S FGS+SL LGG RSL
Sbjct: 1 MSRQLT-HFPRGERLGFSGCSAVLSGGIGSSSASFRARVKG-SASFGSKSLSCLGGSRSL 58
Query: 58 NVASGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNV 117
+++ + + GG R GF G+ FGS LGP CP+VCPPGGI QVTVN+SLLAPLNV
Sbjct: 59 ALSAAARRGGG------RLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNV 112
Query: 118 ELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNL 177
E+DPEIQ+VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKW LLQQLDLNNC+ NL
Sbjct: 113 EMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNL 172
Query: 178 EPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLL 237
EPI EGYISNL+KQLE LSGD VRLDSELRN++D+VEDYKKRYE EIN+RTAAENEFV+L
Sbjct: 173 EPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVL 232
Query: 238 KKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDL 297
KKDVDAAY NKVELQAKV+S+ EIKFF+CL+E EITQIQSHISD S++LSMDNNR+LDL
Sbjct: 233 KKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDL 292
Query: 298 DSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQR 357
DSII EVR QYEEIALKSKAEAE LYQTK QELQ+ AG+HGDDLK TK EISEL RLIQR
Sbjct: 293 DSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQR 352
Query: 358 IRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQE 417
IRSEI NVKKQ ++LETAIADAEQRGD ALKDARAKLDELEGALHQAKEELARMLREYQE
Sbjct: 353 IRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQE 412
Query: 418 LMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGS-VYGFRPSMVSGGY 476
L+SLKLALDMEIATYRKLLESEECRMSGE+P+ VSIS+ISST+ G+ GF S G+
Sbjct: 413 LVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGF-----SMGF 467
Query: 477 VANSSNCISGVCSVRGGEGRSRGS-ANDYKDTLGKGSSLSAPSKKTSR 523
A+SS + +++GS ++ KD L K S S +KK SR
Sbjct: 468 GASSSYSY----KTAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR 511
>gi|5031839 keratin 6A [Homo sapiens]
Length = 564
Score = 568 bits (1465), Expect = e-162
Identities = 313/550 (56%), Positives = 393/550 (71%), Gaps = 54/550 (9%)
Query: 2 SRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRA-------GSKGLSG-----GFGSRSLY 49
S T +S ++++ GFS SA L G S S F + GS GL G GFGSRSLY
Sbjct: 3 STSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLY 62
Query: 50 SLGGVRSLNVASGS-GKSGGYGFGRGRASGFAGS---------------MFGSVAL---- 89
LGG + +++ GS SGGYG G + GF G+ + G L
Sbjct: 63 GLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGF 122
Query: 90 -GPVCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKV 148
GP P VCPPGGI +VTVN+SLL PLN+++DP IQ+VRA+EREQIK LNNKFASFIDKV
Sbjct: 123 GGPGFP-VCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKV 181
Query: 149 RFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRN 208
RFLEQQN+VLETKW LLQ+ + NLEP+ E YI+NLR+QL+++ G+R RLDSELR
Sbjct: 182 RFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRG 241
Query: 209 VRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCL 268
++D+VED+K +YE+EINKRTAAENEFV LKKDVDAAY NKVELQAK +++ EI F R L
Sbjct: 242 MQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRAL 301
Query: 269 FEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQ 328
++AE++Q+Q+HISD SV+LSMDNNRNLDLDSII EV+ QYEEIA +S+AEAE+ YQTK++
Sbjct: 302 YDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYE 361
Query: 329 ELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALK 388
ELQ+ AGRHGDDL+NTK EI+E+ R+IQR+RSEI++VKKQ +NL+ AIADAEQRG+ ALK
Sbjct: 362 ELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALK 421
Query: 389 DARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFP 448
DA+ KL+ LE AL +AK++LAR+L+EYQELM++KLALD+EIATYRKLLE EECR++GE
Sbjct: 422 DAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGV 481
Query: 449 SPVSISIISSTSGGSVYGFRPSMVSGGYVANSSNCISGVCSVRGGEGRSRGSANDYKDTL 508
V+IS++ ST VS GY G V G G GS+ Y L
Sbjct: 482 GQVNISVVQST------------VSSGY--------GGASGVGSGLGLGGGSSYSYGSGL 521
Query: 509 GKGSSLSAPS 518
G G S+ S
Sbjct: 522 GVGGGFSSSS 531
Score = 32.7 bits (73), Expect = 0.83
Identities = 20/50 (40%), Positives = 22/50 (44%)
Query: 36 SKGLSGGFGSRSLYSLGGVRSLNVASGSGKSGGYGFGRGRASGFAGSMFG 85
S G G G S LGG S + SG G GG+ GRA G S G
Sbjct: 494 SSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVG 543
Score = 32.0 bits (71), Expect = 1.4
Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 7/58 (12%)
Query: 11 AAAKGGFSGCSAV-----LSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASGS 63
+ G+ G S V L GGSS S+ +G G+ GGF S S ++GG S +V GS
Sbjct: 491 STVSSGYGGASGVGSGLGLGGGSSYSYGSGL-GVGGGFSSSSGRAIGGGLS-SVGGGS 546
>gi|119703753 keratin 6B [Homo sapiens]
Length = 564
Score = 568 bits (1465), Expect = e-162
Identities = 313/554 (56%), Positives = 394/554 (71%), Gaps = 54/554 (9%)
Query: 2 SRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRA-------GSKGLSG-----GFGSRSLY 49
S T +S ++++ GFS SA L G S S F + GS GL G GFGSRSLY
Sbjct: 3 STSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLY 62
Query: 50 SLGGVRSLNVASGS-GKSGGYGFGRGRASGFAGS---------------MFGSVAL---- 89
LGG + +++ GS SGGYG G + GF G+ + G L
Sbjct: 63 GLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGF 122
Query: 90 -GPVCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKV 148
GP P VCPPGGI +VTVN+SLL PLN+++DP IQ+VRA+EREQIK LNNKFASFIDKV
Sbjct: 123 GGPGFP-VCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKV 181
Query: 149 RFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRN 208
RFLEQQN+VL+TKW LLQ+ + NLEP+ E YI+NLR+QL+ + G+R RLDSELRN
Sbjct: 182 RFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRN 241
Query: 209 VRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCL 268
++D+VED K +YE+EINKRTAAENEFV LKKDVDAAY NKVELQAK +++ EI F R L
Sbjct: 242 MQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRAL 301
Query: 269 FEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQ 328
++AE++Q+Q+HISD SV+LSMDNNRNLDLDSII EV+ QYEEIA +S+AEAE+ YQTK++
Sbjct: 302 YDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYE 361
Query: 329 ELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALK 388
ELQ+ AGRHGDDL+NTK EI+E+ R+IQR+RSEI++VKKQ +NL+ AIADAEQRG+ ALK
Sbjct: 362 ELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALK 421
Query: 389 DARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFP 448
DA+ KL+ LE AL +AK++LAR+L+EYQELM++KLALD+EIATYRKLLE EECR++GE
Sbjct: 422 DAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGV 481
Query: 449 SPVSISIISSTSGGSVYGFRPSMVSGGYVANSSNCISGVCSVRGGEGRSRGSANDYKDTL 508
V+IS++ ST VS GY G V G G GS+ Y L
Sbjct: 482 GQVNISVVQST------------VSSGY--------GGASGVGSGLGLGGGSSYSYGSGL 521
Query: 509 GKGSSLSAPSKKTS 522
G G S+ S + +
Sbjct: 522 GVGGGFSSSSGRAT 535
Score = 33.9 bits (76), Expect = 0.37
Identities = 20/50 (40%), Positives = 23/50 (46%)
Query: 36 SKGLSGGFGSRSLYSLGGVRSLNVASGSGKSGGYGFGRGRASGFAGSMFG 85
S G G G S LGG S + SG G GG+ GRA+G S G
Sbjct: 494 SSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRATGGGLSSVG 543
Score = 30.8 bits (68), Expect = 3.2
Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 7/58 (12%)
Query: 11 AAAKGGFSGCSAV-----LSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASGS 63
+ G+ G S V L GGSS S+ +G G+ GGF S S + GG S +V GS
Sbjct: 491 STVSSGYGGASGVGSGLGLGGGSSYSYGSGL-GVGGGFSSSSGRATGGGLS-SVGGGS 546
>gi|119395754 keratin 5 [Homo sapiens]
Length = 590
Score = 567 bits (1460), Expect = e-161
Identities = 315/582 (54%), Positives = 402/582 (69%), Gaps = 63/582 (10%)
Query: 1 MSRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFR------------------AGSKGLSGG 42
MSRQ + + FS SA+ S +SF AG+ G+ GG
Sbjct: 1 MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGV-GG 59
Query: 43 FGSRSLYSLGGVRSLNVAS---------GSGKSGGYGFGRGRASGFA------------- 80
+GSRSLY+LGG + +++++ G+G GGYGFG G SGF
Sbjct: 60 YGSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGG 119
Query: 81 GSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNK 140
G+ FG GP P VCPPGGI +VTVN+SLL PLN+++DP IQ+VR +EREQIK LNNK
Sbjct: 120 GAGFGGGFGGPGFP-VCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNK 178
Query: 141 FASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRV 200
FASFIDKVRFLEQQN+VL+TKW LLQ+ + NLEP+ E YI+NLR+QL+++ G+R
Sbjct: 179 FASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERG 238
Query: 201 RLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQ 260
RLDSELRN++D+VED+K +YE+EINKRT AENEFV+LKKDVDAAY NKVEL+AKV+++
Sbjct: 239 RLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMD 298
Query: 261 EIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAE 320
EI F + F+AE++Q+Q+H+SD SV+LSMDNNRNLDLDSII EV+ QYEEIA +S+ EAE
Sbjct: 299 EINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAE 358
Query: 321 ALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAE 380
+ YQTK++ELQ AGRHGDDL+NTK+EISE+ R+IQR+R+EI+NVKKQ +NL+ AIADAE
Sbjct: 359 SWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAE 418
Query: 381 QRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEE 440
QRG+ ALKDAR KL ELE AL +AK+++AR+LREYQELM+ KLALD+EIATYRKLLE EE
Sbjct: 419 QRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEE 478
Query: 441 CRMSGEFPSPVSISIISST------------------SGGSVYGFRPSMVSGGYVANSSN 482
CR+SGE PV+IS+++S+ GG + G SG Y ++SS
Sbjct: 479 CRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSG 538
Query: 483 CI--SGVCSVRGGEGRSRGSANDYKDTLGKGSSLSAPSKKTS 522
+ G SV GG G S S G G S+ K S
Sbjct: 539 GVGLGGGLSV-GGSGFSASSGRGLGVGFGSGGGSSSSVKFVS 579
>gi|155969697 keratin 6C [Homo sapiens]
Length = 564
Score = 565 bits (1456), Expect = e-161
Identities = 310/550 (56%), Positives = 393/550 (71%), Gaps = 54/550 (9%)
Query: 2 SRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRA-------GSKGLSG-----GFGSRSLY 49
S T +S ++++ GFS SA L G S S F + GS GL G GFGSRSLY
Sbjct: 3 STSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLY 62
Query: 50 SLGGVRSLNVASGS-GKSGGYGFGRGRASGFAGS---------------MFGSVAL---- 89
LGG + +++ GS SGGYG G + GF G+ + G L
Sbjct: 63 GLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGF 122
Query: 90 -GPVCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKV 148
GP P VCPPGGI +VTVN+SLL PLN+++DP IQ+VRA+EREQIK LNNKFASFIDKV
Sbjct: 123 GGPGFP-VCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKV 181
Query: 149 RFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRN 208
RFLEQQN+VL+TKW LLQ+ + NLEP+ E YI+NLR+QL+++ G+R RLDSELRN
Sbjct: 182 RFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRN 241
Query: 209 VRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCL 268
++D+VED K +YE+EINKRTAAENEFV LKKDVDAAY NKVELQAK +++ EI F R L
Sbjct: 242 MQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRAL 301
Query: 269 FEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQ 328
++AE++Q+Q+HISD SV+LSMDNNRNLDLDSII EV+ QYEEIA +S+AEAE+ YQTK++
Sbjct: 302 YDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYE 361
Query: 329 ELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALK 388
ELQ+ AGRHGDDL+NTK EI+E+ R+IQR+RSEI++VKKQ ++L+ AIADAEQRG+ ALK
Sbjct: 362 ELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMALK 421
Query: 389 DARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFP 448
DA+ KL+ LE AL +AK++LAR+L+EYQELM++KLALD+EIATYRKLLE EECR++GE
Sbjct: 422 DAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGV 481
Query: 449 SPVSISIISSTSGGSVYGFRPSMVSGGYVANSSNCISGVCSVRGGEGRSRGSANDYKDTL 508
V++S++ ST +S GY G V G G GS+ Y L
Sbjct: 482 GQVNVSVVQST------------ISSGY--------GGASGVGSGLGLGGGSSYSYGSGL 521
Query: 509 GKGSSLSAPS 518
G G S+ S
Sbjct: 522 GIGGGFSSSS 531
Score = 32.3 bits (72), Expect = 1.1
Identities = 25/60 (41%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
Query: 4 QFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASGS 63
Q T SG G G L GGSS S+ +G G+ GGF S S ++GG S +V GS
Sbjct: 490 QSTISSGYGGASGV-GSGLGLGGGSSYSYGSGL-GIGGGFSSSSGRAIGGGLS-SVGGGS 546
Score = 32.3 bits (72), Expect = 1.1
Identities = 20/50 (40%), Positives = 22/50 (44%)
Query: 36 SKGLSGGFGSRSLYSLGGVRSLNVASGSGKSGGYGFGRGRASGFAGSMFG 85
S G G G S LGG S + SG G GG+ GRA G S G
Sbjct: 494 SSGYGGASGVGSGLGLGGGSSYSYGSGLGIGGGFSSSSGRAIGGGLSSVG 543
>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
Length = 469
Score = 563 bits (1452), Expect = e-160
Identities = 331/532 (62%), Positives = 382/532 (71%), Gaps = 72/532 (13%)
Query: 1 MSRQFTCKSGAAAKGGFSGCSAVLSGG---SSSSFRAGSKGLSGGFGSRSLYSLGGVRSL 57
MSRQ T + GFSGCSAVLSGG SS+SFRA KG S FGS+SL LGG RSL
Sbjct: 1 MSRQLT-HFPRGERLGFSGCSAVLSGGIGSSSASFRARVKG-SASFGSKSLSCLGGSRSL 58
Query: 58 NVASGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNV 117
+++ + + GG R GF G+ FGS LGP CP+VCPPGGI QVTVN+SLLAPLNV
Sbjct: 59 ALSAAARRGGG------RLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNV 112
Query: 118 ELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNL 177
E+DPEIQ+VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKW LLQQLDLNNC+ NL
Sbjct: 113 EMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNL 172
Query: 178 EPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLL 237
EPI EGYISNL+KQLE LSGD VRLDSELRN++D+VEDYKKRYE EIN+RTAAENEFV+L
Sbjct: 173 EPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVL 232
Query: 238 KKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDL 297
KKDVDAAY NKVELQAKV+S+ EIKFF+CL+E EITQIQSHISD S++LSMDNNR+LDL
Sbjct: 233 KKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDL 292
Query: 298 DSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLA---AGRHGD-DLKNTKNEISELTR 353
DSII EVR QYEEIALKSKAEAE LYQTK +L+ A A + GD LK+ + ++ EL
Sbjct: 293 DSIIAEVRAQYEEIALKSKAEAETLYQTKCADLETAIADAEQRGDCALKDARAKLDEL-- 350
Query: 354 LIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLR 413
+ AL A+ EELARMLR
Sbjct: 351 ------------------------------EGALHQAK--------------EELARMLR 366
Query: 414 EYQELMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGS-VYGFRPSMV 472
EYQEL+SLKLALDMEIATYRKLLESEECRMSGE+P+ VSIS+ISST+ G+ GF
Sbjct: 367 EYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGF----- 421
Query: 473 SGGYVANSSNCISGVCSVRGGEGRSRGS-ANDYKDTLGKGSSLSAPSKKTSR 523
S G+ A+SS + +++GS ++ KD L K S S +KK SR
Sbjct: 422 SMGFGASSSYSY----KTAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR 469
>gi|109255249 keratin 4 [Homo sapiens]
Length = 594
Score = 563 bits (1451), Expect = e-160
Identities = 312/501 (62%), Positives = 382/501 (76%), Gaps = 21/501 (4%)
Query: 16 GFSGCSAVLSGGSSSSFRAGSKG------LSGGFGSRSLYSLGGVRSLNVA-SGS----- 63
GFS SA++ GG +F + S SGGFGSRSLY+L G +S++++ +GS
Sbjct: 88 GFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGAC 147
Query: 64 -GKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPE 122
G +GG+G G G GF GS G GP P VCP GGI +VT+N+SLL PL+VE+DPE
Sbjct: 148 FGGAGGFGTG-GFGGGFGGSFSGKG--GPGFP-VCPAGGIQEVTINQSLLTPLHVEIDPE 203
Query: 123 IQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILE 182
IQKVR +EREQIK LNNKFASFIDKV+FLEQQN+VLETKW LLQQ NLEP+ E
Sbjct: 204 IQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFE 263
Query: 183 GYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVD 242
Y+S LRKQL+TL D+ RL SEL+ ++D VED+K +YEEEINKRTAAEN+FV+LKKDVD
Sbjct: 264 TYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVD 323
Query: 243 AAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIID 302
AAY NKVEL+AKV+S++ EI F + L++AE++Q+Q+H+SD SV+LSMDNNRNLDLDSII
Sbjct: 324 AAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIA 383
Query: 303 EVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEI 362
EVR QYEEIA +SKAEAEALYQTK Q+LQ++ +HGD+LKNTK+EI+EL R+IQR+R+EI
Sbjct: 384 EVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEI 443
Query: 363 ENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLK 422
EN+KKQ L+ ++ADAEQRG+NALKDA +K ELE AL QAKEELARMLREYQELMS+K
Sbjct: 444 ENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVK 503
Query: 423 LALDMEIATYRKLLESEECRMSGEFPSPVSISIIS-STSGGSVYGFRPSMVSGGYVANSS 481
LALD+EIATYRKLLE EE RMSGE S VSIS++S STS G + G + SG SS
Sbjct: 504 LALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISG---GLGSGSGFGLSS 560
Query: 482 NCISGVCSVRGGEGRSRGSAN 502
SG S G G GS++
Sbjct: 561 GFGSGSGSGFGFGGSVSGSSS 581
Score = 33.1 bits (74), Expect = 0.64
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 13/61 (21%)
Query: 22 AVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASGSGKSGGYGFGRGRASGFAG 81
+V+SG +S+ G+SGG GS S + L GSG G+GFG G SG +
Sbjct: 535 SVVSGSTSTG------GISGGLGSGSGFGLSS------GFGSGSGSGFGFG-GSVSGSSS 581
Query: 82 S 82
S
Sbjct: 582 S 582
>gi|153791158 keratin 75 [Homo sapiens]
Length = 551
Score = 563 bits (1450), Expect = e-160
Identities = 316/552 (57%), Positives = 404/552 (73%), Gaps = 38/552 (6%)
Query: 1 MSRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFR--------AGSKGLS------GGFGSR 46
MSRQ + + ++ GFS SA+ S F AGS GL FGSR
Sbjct: 1 MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR 60
Query: 47 SLYSLGGVRSLNVASGSGKSGGYGFGRGRAS---------GFAGSMFGSVALGPVCPTVC 97
SLY+LGG + +++ +G G S GFG GRAS G+ G + G + GP P VC
Sbjct: 61 SLYNLGGAKRVSI-NGCGSSCRSGFG-GRASNRFGVNSGFGYGGGVGGGFS-GPSFP-VC 116
Query: 98 PPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQV 157
PPGGI +VTVN+SLL PL++++DP IQ+VRA+EREQIK LNNKFASFIDKVRFLEQQN+V
Sbjct: 117 PPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKV 176
Query: 158 LETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYK 217
LETKW LLQ+ + NLEP+ + Y S LR+QLE+++ +R RL++ELRN++DVVED+K
Sbjct: 177 LETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFK 236
Query: 218 KRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQ 277
RYE+EINKRTAAENEFV LKKDVDAAY NKVEL+AKV+S+ +EI F +F+AE++Q+Q
Sbjct: 237 VRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQ 296
Query: 278 SHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRH 337
+ + D SV+LSMDNNRNLDLDSII EV+ QYE+IA +S+AEAE+ YQTK++ELQ+ AGRH
Sbjct: 297 TQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRH 356
Query: 338 GDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDEL 397
GDDL+NTK EISE+ R+IQR+R+EI++VKKQ S+L+TAIADAEQRG+ ALKDARAKL +L
Sbjct: 357 GDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDL 416
Query: 398 EGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISIIS 457
E AL +AK+++AR+LREYQELM++KLALD+EIATYRKLLE EECR+SGE SPV+IS+++
Sbjct: 417 EEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVT 476
Query: 458 ST------SGGSVYGFRPSMVSG-GYVANSSNCISGVCSVRGGEGRSRGSANDYKDTLGK 510
ST SG S+ G + G GY S SG S+ G G S SA + G
Sbjct: 477 STLSSGYGSGSSIGGGNLGLGGGSGY----SFTTSGGHSLGAGLGGSGFSATSNRGLGGS 532
Query: 511 GSSLSAPSKKTS 522
GSS+ S +S
Sbjct: 533 GSSVKFVSTTSS 544
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 559 bits (1441), Expect = e-159
Identities = 313/568 (55%), Positives = 398/568 (70%), Gaps = 63/568 (11%)
Query: 1 MSRQFTCKSGAAAKGGFSGCSAVL--------------SGGSSSSFRA-----GSKGLSG 41
MSRQF+ +SG + GGFS SA + SGG F + GS G G
Sbjct: 1 MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGG 60
Query: 42 GFGSRSLYSLGGVRSLNVA------SGSGKSGGYG------------------------- 70
GFGSRSL +LGG +S++++ GSG GGYG
Sbjct: 61 GFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFG 120
Query: 71 -FGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQ 129
FG G GF G FG G VCPPGGI +VT+N+SLL PLNVE+DPEIQKV+++
Sbjct: 121 GFGSG-GGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSR 179
Query: 130 EREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLR 189
EREQIK+LNN+FASFIDKVRFLEQQNQVL+TKWELLQQ+D + +NLEP E +I+NLR
Sbjct: 180 EREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLR 239
Query: 190 KQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKV 249
++++ L D+ RLDSEL+N++D+VEDY+ +YE+EINKRT AENEFV +KKDVD AY KV
Sbjct: 240 RRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKV 299
Query: 250 ELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYE 309
+LQAK++++ QEI F L++AE++Q+Q+ IS+ +VILSMDNNR+LDLDSII EV+ QYE
Sbjct: 300 DLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYE 359
Query: 310 EIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQA 369
+IA KSKAEAE+LYQ+K++ELQ+ AGRHGD ++N+K EISEL R+IQR+RSEI+NVKKQ
Sbjct: 360 DIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQI 419
Query: 370 SNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEI 429
SNL+ +I+DAEQRG+NALKDA+ KL++LE AL QAKE+LAR+LR+YQELM+ KLALD+EI
Sbjct: 420 SNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEI 479
Query: 430 ATYRKLLESEECRMSGEFPSPVSISIISS----TSGGSVYGFRPSMVSGGYVANSSNCIS 485
ATYR LLE EE RMSGE VS+S+ +S + GGS G GGY + S+ S
Sbjct: 480 ATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGG-----GGGGYGSGGSSYGS 534
Query: 486 GVCSV--RGGEGRSRGSANDYKDTLGKG 511
G S GG G RGS + G G
Sbjct: 535 GGGSYGSGGGGGGGRGSYGSGGSSYGSG 562
Score = 44.7 bits (104), Expect = 2e-04
Identities = 29/71 (40%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
Query: 15 GGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLY----SLGGVRSLNVASGSGKSGGYG 70
GG G + SGGSS GS G GG G Y S GG R + G G SGG G
Sbjct: 544 GGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRG 603
Query: 71 FGRGRASGFAG 81
G G + G G
Sbjct: 604 SGGGSSGGSIG 614
Score = 37.7 bits (86), Expect = 0.026
Identities = 35/103 (33%), Positives = 39/103 (37%), Gaps = 15/103 (14%)
Query: 1 MSRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGS-RSLYSLGGVR---- 55
+S T SG ++GG G SGGSS GS G GG G R Y GG
Sbjct: 505 VSTSHTTISGGGSRGGGGGGYG--SGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSG 562
Query: 56 --SLNVASGSGKSGGYGFG------RGRASGFAGSMFGSVALG 90
S G G G YG G RG + G G G G
Sbjct: 563 GGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSG 605
Score = 35.8 bits (81), Expect = 0.098
Identities = 32/81 (39%), Positives = 37/81 (45%), Gaps = 12/81 (14%)
Query: 15 GGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASGSGKSGGYGFGRG 74
GG G + SG SS +R GS G GG S GG SG G SGG GRG
Sbjct: 570 GGGGGHGSYGSGSSSGGYRGGSGG-GGGGSS------GG-----RGSGGGSSGGSIGGRG 617
Query: 75 RASGFAGSMFGSVALGPVCPT 95
+SG S GS ++ V T
Sbjct: 618 SSSGGVKSSGGSSSVKFVSTT 638
>gi|153791670 keratin 76 [Homo sapiens]
Length = 638
Score = 557 bits (1436), Expect = e-159
Identities = 329/582 (56%), Positives = 400/582 (68%), Gaps = 62/582 (10%)
Query: 1 MSRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGG----------FGSRSLYS 50
M+RQ KS + GFSG SAV+SG S S A S G GG FGSRSLY+
Sbjct: 1 MNRQVCKKSFSGRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYN 60
Query: 51 LGGVRSLN--VASGSGKSGGYGFGR---GRASGFAGSMFGSV------------------ 87
LG +S++ VA+GS ++GG+G GR G A G+ G GS
Sbjct: 61 LGSNKSISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAG 120
Query: 88 ----ALGPVCPTVCP----------------PGGIHQVTVNESLLAPLNVELDPEIQKVR 127
A G P V PGGI +V VN+SLL PLNVE+DP+I +V+
Sbjct: 121 GFGGAGGFGGPGVFGGPGSFGGPGGFGPGGFPGGIQEVIVNQSLLQPLNVEIDPQIGQVK 180
Query: 128 AQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISN 187
AQEREQIK LNNKFASFIDKVRFLEQQN+VLETKWELLQQ + ++LEP E YIS
Sbjct: 181 AQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFESYISF 240
Query: 188 LRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYAN 247
L KQL++L G+R L+ EL++++D+VED+KK+YE+EINKRTAAENEFV LKKDVDAA+ N
Sbjct: 241 LCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDAAFMN 300
Query: 248 KVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQ 307
KVELQAKV+S+ E+ F R L+E E++Q+QSH SD SV+LSMDNNR LDL SII EVR Q
Sbjct: 301 KVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAEVRAQ 360
Query: 308 YEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKK 367
YEEIA +SK+EAEALYQTK ELQ AGRHGDDL+NTK+EI EL R+IQR+R+EIENVKK
Sbjct: 361 YEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIENVKK 420
Query: 368 QASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDM 427
Q +NL+TAIA+AEQRG+ ALKDA AKL +L+ AL +AK++LAR+LR+YQELM++KLALD+
Sbjct: 421 QNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKLALDV 480
Query: 428 EIATYRKLLESEECRMSGEFPSPVSISIIS---STSGGS-----VYGFRPSMVSGGYVAN 479
EIATYRKLLE EECRMSGE S V IS++S STSG S V+G SGGY
Sbjct: 481 EIATYRKLLEGEECRMSGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGG 540
Query: 480 SSNCISGVCSVRGGEGRSRGSANDYKDTLGKGSSLSAPSKKT 521
SS+ S V GG G G + T G+GSS S S +
Sbjct: 541 SSSSSSSGYGVSGGSGSGYGGVSS-GSTGGRGSSGSYQSSSS 581
Score = 38.9 bits (89), Expect = 0.012
Identities = 33/83 (39%), Positives = 40/83 (48%), Gaps = 14/83 (16%)
Query: 14 KGGFSGCSAV---LSGGSSSSFRAGSKGLSGGFGSRSLYS-------LGGVRSLNVA-SG 62
KGG S S+ +SGGS S + S G +GG GS Y LGG S++V+ SG
Sbjct: 538 KGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGGAGSISVSHSG 597
Query: 63 SGKSGG---YGFGRGRASGFAGS 82
G S G G G SG GS
Sbjct: 598 MGSSSGSIQTSGGSGYKSGGGGS 620
Score = 36.6 bits (83), Expect = 0.057
Identities = 30/83 (36%), Positives = 37/83 (44%), Gaps = 14/83 (16%)
Query: 6 TCKSGAAAKGGFSGCSAVLSGG---SSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASG 62
T S +++G F G S SGG SSS + G+SGG GS GGV
Sbjct: 515 TSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGS----GYGGV-------S 563
Query: 63 SGKSGGYGFGRGRASGFAGSMFG 85
SG +GG G S +GS G
Sbjct: 564 SGSTGGRGSSGSYQSSSSGSRLG 586
>gi|109148552 keratin 3 [Homo sapiens]
Length = 628
Score = 553 bits (1424), Expect = e-157
Identities = 326/587 (55%), Positives = 397/587 (67%), Gaps = 80/587 (13%)
Query: 1 MSRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGL----------SGGFGSRSLYS 50
MSRQ + SG ++G FSG SAV+SG S S A S G +GGFGSRSLY+
Sbjct: 1 MSRQASKTSGGGSQG-FSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYN 59
Query: 51 LGGVRSLN--VASGSGKSGGYG---------------------------FGRGR------ 75
LGG +S++ VA+G ++GG+G FG GR
Sbjct: 60 LGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGF 119
Query: 76 --ASGFAGS--------------MFGSVALGPVCPTVCP--------PGGIHQVTVNESL 111
A GF G+ GS G P PGGI +VT+N+SL
Sbjct: 120 GGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSL 179
Query: 112 LAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLN 171
L PLNVE+DP+I +V+AQEREQIK LNNKFASFIDKVRFLEQQN+VLETKW LLQQ +
Sbjct: 180 LQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTS 239
Query: 172 NCK--NNLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTA 229
+ NNLEP+ E +I+ LR L+ + G+R RLDSEL+N+ D+VED+KK+YE+EINKRTA
Sbjct: 240 SISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTA 299
Query: 230 AENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSM 289
AENEFV LKKDVD+AY NKVELQAKV+++ EI F R L++AE++Q+QSHISD SV+LSM
Sbjct: 300 AENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSM 359
Query: 290 DNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEIS 349
DNNR+LDLDSII EVR QYE+IA +SKAEAEALYQTK ELQ AGRHGDDL+NTK+EI
Sbjct: 360 DNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEII 419
Query: 350 ELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELA 409
EL R+IQR+R+EIE VKKQ +NL+TAIA+AEQ G+ ALKDA AKL EL+ AL QAK++LA
Sbjct: 420 ELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLA 479
Query: 410 RMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISII-SSTSGGSVYGFR 468
R+LR+YQELM++KLALD+EIATYRKLLE EE RMSGE PS VSIS++ SST+ S G+
Sbjct: 480 RLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGY- 538
Query: 469 PSMVSGGYVANSSNCISGVCSVRGGEGR--SRGSANDYKDTLGKGSS 513
GGY + G S GG G RG G GSS
Sbjct: 539 ----GGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSS 581
Score = 39.3 bits (90), Expect = 0.009
Identities = 29/67 (43%), Positives = 37/67 (55%), Gaps = 6/67 (8%)
Query: 28 SSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASGS--GKSGGYGFG---RGRASGFA-G 81
SSS+ A + G GG+G LGG S SGS G+ GG G G G +SGF+ G
Sbjct: 527 SSSTTSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGG 586
Query: 82 SMFGSVA 88
S FGS++
Sbjct: 587 SGFGSIS 593
Score = 38.1 bits (87), Expect = 0.020
Identities = 31/82 (37%), Positives = 34/82 (41%), Gaps = 23/82 (28%)
Query: 10 GAAAKGGFSGCSAVLSGGSSSSF-RAGSKGLSGGFGSRSLYSLGGVRSLNVASGSGKSGG 68
G GGFS GGS S F R G G+ GGFG S SG SGG
Sbjct: 547 GGGLGGGFSA-----GGGSGSGFGRGGGGGIGGGFGGGS---------------SGFSGG 586
Query: 69 YGFG--RGRASGFAGSMFGSVA 88
GFG G G +G F S +
Sbjct: 587 SGFGSISGARYGVSGGGFSSAS 608
Score = 29.6 bits (65), Expect = 7.0
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 10 GAAAKGGFSGCSAVLSGGSSSSFRAGSK-GLSGGFGSRSLYSLGGVRSLNVASGSGK 65
G GGF G S+ SGGS +G++ G+SGG G S + GG + +S S +
Sbjct: 569 GGGIGGGFGGGSSGFSGGSGFGSISGARYGVSGG-GFSSASNRGGSIKFSQSSQSSQ 624
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 539 bits (1389), Expect = e-153
Identities = 312/563 (55%), Positives = 392/563 (69%), Gaps = 52/563 (9%)
Query: 1 MSRQFTCKSGAAAKGG-----FSGCSAVLSGGS---SSSFRA------GSKGLSGG-FGS 45
MS Q +CKS GG FS SAV+SGGS +SSF G G GG FGS
Sbjct: 1 MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGS 60
Query: 46 RSLYSLGGVRSLNVA-----SGSGKSGGYG-----FGRGRA----SGFAGSMFGSVALGP 91
RSL LGG +S++++ G G +GG+G FG G + SGF+G FG G
Sbjct: 61 RSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGG 120
Query: 92 -----------VCPTVCP--------PGGIHQVTVNESLLAPLNVELDPEIQKVRAQERE 132
V P PGGIH+V+VN+SLL PLNV++DPEIQ V+AQERE
Sbjct: 121 GRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQERE 180
Query: 133 QIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQL 192
QIK LNNKFASFIDKVRFLEQQNQVL+TKWELLQQ+++ NLEPI +GYI +L++ L
Sbjct: 181 QIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYL 240
Query: 193 ETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQ 252
+ L+ +R +SEL N++D+VEDYKK+YE+EINKRTAAEN+FV LKKDVD AY KVELQ
Sbjct: 241 DGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQ 300
Query: 253 AKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIA 312
+KV+ ++QEI+F + L++AEI+QI ++D +VILSMDN+RNLDLDSII EV+ QYEEIA
Sbjct: 301 SKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIA 360
Query: 313 LKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNL 372
+SK EAEALY +K++ELQ+ GRHGD LK K EISEL R+IQR++ EI +VKKQ N+
Sbjct: 361 QRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNV 420
Query: 373 ETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATY 432
+ AIADAEQRG++ALKDAR KL++LE AL QAKE+LAR+LR+YQELM++KLALD+EIATY
Sbjct: 421 QDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATY 480
Query: 433 RKLLESEECRMSGEFPSPVSISIISSTSGGSVYGFRPSMVSGGYVANSSNCISGVCSVRG 492
RKLLE EECRMSG+ S V++S+ SST +V SGG ++S S S G
Sbjct: 481 RKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYG 540
Query: 493 GEGRSRGSANDYKDTLGKGSSLS 515
GR GS + G G S+S
Sbjct: 541 SGGRQSGS----RGGSGGGGSIS 559
Score = 43.9 bits (102), Expect = 4e-04
Identities = 37/90 (41%), Positives = 45/90 (50%), Gaps = 13/90 (14%)
Query: 10 GAAAKGGFS-GCSAVLSGGSSSSFRAGSKGLSGGFGSRS--LYSLGGVRSLNVASGSG-- 64
G+++ GG+S G S+ SGG S GS+G SGG GS S Y GG SG G
Sbjct: 525 GSSSGGGYSSGSSSYGSGGRQS----GSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSK 580
Query: 65 ----KSGGYGFGRGRASGFAGSMFGSVALG 90
GGYG G G+ S GS GS + G
Sbjct: 581 GGSISGGGYGSGGGKHSSGGGSRGGSSSGG 610
Score = 41.2 bits (95), Expect = 0.002
Identities = 30/89 (33%), Positives = 36/89 (40%), Gaps = 5/89 (5%)
Query: 3 RQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVAS- 61
RQ + G+ G SG GGS + +G G S GG S S
Sbjct: 544 RQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSR 603
Query: 62 -GSGKSGGYGFGRGRAS---GFAGSMFGS 86
GS GGYG G G +S G +G FGS
Sbjct: 604 GGSSSGGGYGSGGGGSSSVKGSSGEAFGS 632
>gi|194018511 keratin 77 [Homo sapiens]
Length = 578
Score = 536 bits (1381), Expect = e-152
Identities = 299/564 (53%), Positives = 392/564 (69%), Gaps = 48/564 (8%)
Query: 1 MSRQFTCKSG--AAAKGGFSGCSAVLSGGSSSSFRA----------GSKGLSG-GFGSRS 47
MS QF+ +S + ++ +S S+ SGG S + + G G+ G GFGSRS
Sbjct: 1 MSHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRS 60
Query: 48 LYSLGGVRSLNV------ASG---SGKSGGYGFGRG------RASGFAGSMFGSVALGPV 92
LY+LGG RS+++ SG G GG+G GRG A GF G FG G
Sbjct: 61 LYNLGGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTS 120
Query: 93 ------CPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFID 146
CPPGGI +VT+N+SLL PL++E+DPEIQ+++ QEREQI LNNKFASFID
Sbjct: 121 NFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFID 180
Query: 147 KVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSEL 206
KVRFLEQQNQVL+TKWELLQQ++ + NNLEP+LE YI +LR+Q++ LS +++R ++E+
Sbjct: 181 KVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEV 240
Query: 207 RNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFR 266
R+++DVVEDYK +YE+EINKRT +EN+FV+LKKDVDAAY +KV+L+++V+++ E+ F +
Sbjct: 241 RSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLK 300
Query: 267 CLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTK 326
LF E++Q+Q+HISD +VILSMDNNR+LDLDSIID VRTQYE IA +SK EAEALYQTK
Sbjct: 301 YLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTK 360
Query: 327 FQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNA 386
+QELQ+ AGRHGDDLKN+K EI+EL R +QR+++EI NVKKQ +++ I+DAE+RG+ A
Sbjct: 361 YQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQA 420
Query: 387 LKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGE 446
L+DA KL +LE AL Q+KEELAR+LR+YQ ++ +KL+LD+EIATYR+LLE EE RMSGE
Sbjct: 421 LQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGE 480
Query: 447 FPSPVSISIISS-------TSGGSVYGFRPSMVSGGYVANSSNCISGVCSVRGGEGRSRG 499
S VSIS+ +S GG YG SGGY S G S RGG R R
Sbjct: 481 LQSHVSISVQNSQVSVNGGAGGGGSYG------SGGYGGGSGGGYGGGRSYRGGGARGR- 533
Query: 500 SANDYKDTLGKGSSLSAPSKKTSR 523
S Y G G S ++ R
Sbjct: 534 SGGGYGSGCGGGGGSYGGSGRSGR 557
>gi|32567786 keratin 6L [Homo sapiens]
Length = 535
Score = 535 bits (1379), Expect = e-152
Identities = 294/518 (56%), Positives = 377/518 (72%), Gaps = 23/518 (4%)
Query: 9 SGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASGSG---- 64
SG+ A+ FS + S GS G +GGFGSRSLY+LGG +S++V+ G
Sbjct: 25 SGSQARTSFSSVTVSRSSGSGGGAHCGPG--TGGFGSRSLYNLGGHKSISVSVAGGALLG 82
Query: 65 -KSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPEI 123
GG+GFG + F G G GP CPPGGI +VTVN+SLL PL+VE+DPEI
Sbjct: 83 RALGGFGFG---SRAFMGQGAGRQTFGP----ACPPGGIQEVTVNQSLLTPLHVEIDPEI 135
Query: 124 QKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQ--LDLNNCKNNLEPIL 181
Q+VR QEREQIK LNNKFASFIDKVRFLEQQN+VLETKW LLQ+ +L +NNLEP+
Sbjct: 136 QRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLF 195
Query: 182 EGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDV 241
E Y+ ++R L+ L +R RLDSELRNV+D+VED+K +YE+EINK TAAENEFV+LKKDV
Sbjct: 196 EAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDV 255
Query: 242 DAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSII 301
DAAY +++L KV ++ QEI F + L+E E++Q+Q+H+S+ +V+LSMDNNRNLDLDSII
Sbjct: 256 DAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSII 315
Query: 302 DEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSE 361
EV+ QYE IA +S+AEAEA YQTK++ELQ+ AG+HGD+L++TKNEI+ELTR IQR++ E
Sbjct: 316 AEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGE 375
Query: 362 IENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSL 421
+ KKQ L+TAIA+AEQRG+ ALKDA+ KL +L+ ALHQAKE+L R+LR+YQELM++
Sbjct: 376 ADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNV 435
Query: 422 KLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTS---GGSVYGFRPSMV---SGG 475
KLALD+EIATYRKLLESEE RMSGE PS VSIS+ +++ GG F + SGG
Sbjct: 436 KLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTTVCGGGAASFGGGISLGGSGG 495
Query: 476 YVANSSNCISGVCSVRGGEGRSRGSANDYKDTLGKGSS 513
+ G +V+GG S G++ K T K SS
Sbjct: 496 ATKGGFSTNVGYSTVKGGP-VSAGTSILRKTTTVKTSS 532
>gi|67782365 keratin 7 [Homo sapiens]
Length = 469
Score = 459 bits (1182), Expect = e-129
Identities = 252/443 (56%), Positives = 327/443 (73%), Gaps = 16/443 (3%)
Query: 43 FGSRSLYSLGGVRSLNVAS----GSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCP 98
F SRS G + ++S G G S YG G R S +G GPV
Sbjct: 10 FTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYG----GPV------ 59
Query: 99 PGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVL 158
GI +VT+N+SLLAPL ++ DP +Q+VR +E EQIK LNNKFASFIDKVRFLEQQN++L
Sbjct: 60 GAGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLL 119
Query: 159 ETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKK 218
ETKW LLQ+ + + L I E I+ LR QLE L D RL++ELR+++DVVED+K
Sbjct: 120 ETKWTLLQE-QKSAKSSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKN 178
Query: 219 RYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQS 278
+YE+EIN RTAAENEFV+LKKDVDAAY +KVEL+AKV++++ EI F R L E E+T++QS
Sbjct: 179 KYEDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQS 238
Query: 279 HISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHG 338
ISD SV+LSMDN+R+LDLD II EV+ QYEE+A S+AEAEA YQTKF+ LQ AG+HG
Sbjct: 239 QISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHG 298
Query: 339 DDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELE 398
DDL+NT+NEISE+ R IQR+++EI+N+K Q + LE AIA+AE+RG+ ALKDARAK +ELE
Sbjct: 299 DDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELE 358
Query: 399 GALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISS 458
AL + K+++AR LREYQELMS+KLALD+EIATYRKLLE EE R++G+ V+IS+++S
Sbjct: 359 AALQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNS 418
Query: 459 TSGGSVYGFRPSMVSGGYVANSS 481
T GGS G + GG + +++
Sbjct: 419 T-GGSSSGGGIGLTLGGTMGSNA 440
>gi|89357932 keratin 5b [Homo sapiens]
Length = 520
Score = 457 bits (1175), Expect = e-128
Identities = 257/501 (51%), Positives = 333/501 (66%), Gaps = 25/501 (4%)
Query: 9 SGAAAKGGFSG---CSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASGSGK 65
S A+ GFS CSA G S F + GGF SRSL S GG + S G
Sbjct: 4 SPCRAQRGFSARSACSARSRGRSRGGFSS-----RGGFSSRSLNSFGGCLEGSRGSTWGS 58
Query: 66 SGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQK 125
G G G SG G ++CPPGGI +VT+N++LL PL +E+DP+ Q
Sbjct: 59 GGRLGVRFGEWSGGPGL------------SLCPPGGIQEVTINQNLLTPLKIEIDPQFQV 106
Query: 126 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYI 185
VR QE ++I+ LNN+FASFIDKVRFLEQQN+VLETKW LLQQ L+ + LEP+ E +
Sbjct: 107 VRTQETQEIRTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACL 166
Query: 186 SNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAY 245
LRKQLE L G+R LD+EL+ RD E+YK +YEEE ++R EN+FV+LKKDVD +
Sbjct: 167 DQLRKQLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVF 226
Query: 246 ANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVR 305
+K+EL+ K+E++ + + F + L E E+ Q+Q+ SD SV+LSMDNNR LD SII EVR
Sbjct: 227 LSKMELEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVR 286
Query: 306 TQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENV 365
+YEEIA SKAEAEALYQTK+QELQ++A HGD ++ TK +IS+L + IQR++S+ EN+
Sbjct: 287 ARYEEIARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENL 346
Query: 366 KKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLAL 425
KKQ ++L+ AI DAEQRG+ ALKDA+AK+DELE AL AK+ LAR+L EYQEL S KL+L
Sbjct: 347 KKQNASLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSL 406
Query: 426 DMEIATYRKLLESEECRMSGEFPSPVSISIISST---SGGSVYGFRPSMVSGGYVANSSN 482
D+EIATYR+LLE EECRMSGE S V+IS + + SGG G + G + +
Sbjct: 407 DVEIATYRRLLEGEECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGS 466
Query: 483 CISGVCSVRGGEGRSRGSAND 503
C + + V GG GS D
Sbjct: 467 CCTSI--VTGGSNIILGSGKD 485
>gi|4504919 keratin 8 [Homo sapiens]
Length = 483
Score = 446 bits (1148), Expect = e-125
Identities = 246/446 (55%), Positives = 319/446 (71%), Gaps = 30/446 (6%)
Query: 28 SSSSFRAGSKGLSGGFGSRSLYSLGGVR----SLNVASGSGKSGGYGFGRGRASGFAGSM 83
+ S++ + G F SRS S G R S + S GG G G G ASG
Sbjct: 6 TQKSYKVSTSG-PRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGM---- 60
Query: 84 FGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFAS 143
GGI VTVN+SLL+PL +E+DP IQ VR QE+EQIK LNNKFAS
Sbjct: 61 ----------------GGITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFAS 104
Query: 144 FIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLD 203
FIDKVRFLEQQN++LETKW LLQQ ++N++ + E YI+NLR+QLETL ++++L+
Sbjct: 105 FIDKVRFLEQQNKMLETKWSLLQQQ--KTARSNMDNMFESYINNLRRQLETLGQEKLKLE 162
Query: 204 SELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIK 263
+EL N++ +VED+K +YE+EINKRT ENEFVL+KKDVD AY NKVEL++++E + EI
Sbjct: 163 AELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEIN 222
Query: 264 FFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALY 323
F R L+E EI ++QS ISD SV+LSMDN+R+LD+DSII EV+ QYE+IA +S+AEAE++Y
Sbjct: 223 FLRQLYEEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMY 282
Query: 324 QTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRG 383
Q K++ELQ AG+HGDDL+ TK EISE+ R I R+++EIE +K Q ++LE AIADAEQRG
Sbjct: 283 QIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRG 342
Query: 384 DNALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRM 443
+ A+KDA AKL ELE AL +AK+++AR LREYQELM++KLALD+EIATYRKLLE EE R+
Sbjct: 343 ELAIKDANAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRL 402
Query: 444 -SGEFPSPVSISIISSTSGG--SVYG 466
SG + S +GG S YG
Sbjct: 403 ESGMQNMSIHTKTTSGYAGGLSSAYG 428
>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
Length = 600
Score = 440 bits (1131), Expect = e-123
Identities = 262/531 (49%), Positives = 346/531 (65%), Gaps = 47/531 (8%)
Query: 3 RQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGS---------KGLSGGFGSRSLYSLGG 53
R + SG G FS CSA ++ + + FRA S +GL G FGSRS+ + G
Sbjct: 4 RSYRVSSGHRV-GNFSSCSA-MTPQNLNRFRANSVSCWSGPGFRGL-GSFGSRSVITFGS 60
Query: 54 VRSLNVASGS---------GKSGGYGFGRGRASGFA-----------------GSMFGSV 87
A GS G G GFG GR G G FG
Sbjct: 61 YSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGP 120
Query: 88 ALGPVCPTVCPPGG--IHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFI 145
G V P I VTVN+SLL PLN+E+DP Q+V+ E+EQIK LNNKFASFI
Sbjct: 121 GFGYRVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFI 180
Query: 146 DKVRFLEQQNQVLETKWELLQQLDLNNC-KNNLEPILEGYISNLRKQLETLSGDRVRLDS 204
DKVRFLEQQN++LETKW LQ+ C ++NLEP+ E YI+NLR+QLE L D+ RL +
Sbjct: 181 DKVRFLEQQNKLLETKWSFLQE---QKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQA 237
Query: 205 ELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKF 264
E +++DV+E +KK+YEEE+ R AENEFV LKKDVDAA+ NK +L+A V+++ QEI F
Sbjct: 238 ERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDF 297
Query: 265 FRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQ 324
+ L+ EI +QSHIS+ SVI+ MDN+R+L+LD II EV+ QYEE+A +S+A+AEA YQ
Sbjct: 298 LKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQ 357
Query: 325 TKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGD 384
TK++E+Q+ AG+H D+L+N +NEI+ELTRLIQR+++EIE+ K Q + LE A+A+AEQ+G+
Sbjct: 358 TKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGE 417
Query: 385 NALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMS 444
L DA+ KL +LE AL QAK+++AR L EYQELM+ KL LD+EIATYR+LLE EE R+
Sbjct: 418 ATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLC 477
Query: 445 GEFPSPVSISIISSTSGGSVYGFRPSMVSGGYVANSSNCISGVCSVRGGEG 495
E PV+IS +SS+ GG V G P +V+G ++ SG SV G
Sbjct: 478 -EGVGPVNIS-VSSSRGGLVCGPEP-LVAGSTLSRGGVTFSGSSSVCATSG 525
>gi|4504935 keratin 85 [Homo sapiens]
Length = 507
Score = 416 bits (1070), Expect = e-116
Identities = 235/495 (47%), Positives = 325/495 (65%), Gaps = 25/495 (5%)
Query: 3 RQFTCKSGAAAKGGFSGCSAVL--SGGSSSSFRAGSKGLS-----GGFGSRSLYSLGGVR 55
R + SG FS CSAV +G A +G+S GFGSRSL +LG
Sbjct: 4 RSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLGSCG 63
Query: 56 SLNVASGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPL 115
+A G ++G G G SG G P C T V+VNESLL PL
Sbjct: 64 P-RIAVGGFRAGSCGRSFGYRSG------GVCGPSPPCITT--------VSVNESLLTPL 108
Query: 116 NVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKN 175
N+E+DP Q V+ +E+EQIK+LN++FA+FIDKVRFLEQQN++LETKW+ Q + C++
Sbjct: 109 NLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ--NQRCCES 166
Query: 176 NLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFV 235
NLEP+ GYI LR++ E + D RL SEL +V++V+E YKK+YEEE+ R AENEFV
Sbjct: 167 NLEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFV 226
Query: 236 LLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNL 295
+LKKDVD AY K +L+A VE++ +E F R L+E EI +Q+HISD SVI+ MDN+R+L
Sbjct: 227 VLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDL 286
Query: 296 DLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLI 355
++D II E++ QY+++A +S+AEAE+ Y++K +E++ RHG+ L+ TK EI+EL R+I
Sbjct: 287 NMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMI 346
Query: 356 QRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREY 415
QR+ +EIEN K Q + LE A+A+AEQ+G+ AL DAR KL ELEGAL +AK+++A +L+EY
Sbjct: 347 QRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEY 406
Query: 416 QELMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGSVYGFRPSMVSGG 475
QE+M+ KL LD+EIATYR+LLE EE R+ E V++ + SS G S G S G
Sbjct: 407 QEVMNSKLGLDIEIATYRRLLEGEEHRLC-EGVGSVNVCVSSSRGGVSCGGLSYSTTPGR 465
Query: 476 YVANSSNCISGVCSV 490
+ + + I G +V
Sbjct: 466 QITSGPSAIGGSITV 480
>gi|27477127 keratin 82 [Homo sapiens]
Length = 513
Score = 415 bits (1067), Expect = e-116
Identities = 253/517 (48%), Positives = 343/517 (66%), Gaps = 34/517 (6%)
Query: 17 FSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASGSGKSGGYGFGRGR- 75
FS SAV+ + A SKG G R L +LG + S ++ + GFGR R
Sbjct: 17 FSSYSAVMP--RMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCN-------VGFGRPRV 67
Query: 76 ASGFAGSMFG-SVALGPVC-PTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQ 133
AS G++ G LG C P+ C I VT+NESLL PL +E+DP +Q+V+ E+EQ
Sbjct: 68 ASRCGGTLPGFGYRLGATCGPSAC----ITPVTINESLLVPLALEIDPTVQRVKRDEKEQ 123
Query: 134 IKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLE 193
IK LNN+FASFI+KVRFLEQ+N++LETKW +QQ C+ N+EPI EGYIS LR+QL+
Sbjct: 124 IKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRC--CQTNIEPIFEGYISALRRQLD 181
Query: 194 TLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQA 253
+SGDRVRL+SEL +++ +E YKK+YEEE++ R ENEFV LKKDVD A+ K +L+
Sbjct: 182 CVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLET 241
Query: 254 KVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIAL 313
E++ QEI F + L+E EI +QS IS+ SVI+ MDN+R LD+D II E++ QY++IA
Sbjct: 242 NAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIAS 301
Query: 314 KSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLE 373
+SKAEAEA YQ +++EL++ AG H D+L+N KNEI E+ +LIQR++ E ENVK Q LE
Sbjct: 302 RSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLE 361
Query: 374 TAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYR 433
AIA+AEQ+G+ AL DA+ KL LE AL +AK+++A +L+EYQE+M+ KL LD+EIATYR
Sbjct: 362 GAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYR 421
Query: 434 KLLESEECRMSGEFPSPVSISIISSTSGGSVY---GFRPSMVSGGYVANSSNC-ISGV-- 487
+LLE EE R+ E PV+IS +SS+ G +Y G ++S G + ++ C I G
Sbjct: 422 RLLEGEEHRLC-EGIGPVNIS-VSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGE 479
Query: 488 ----CSVRGGEGRSRGSANDYKDTLGKGSSLSAPSKK 520
C +G S GS TLG G S+PS K
Sbjct: 480 LYVPCEPQG--LLSCGSGRKSSMTLGAGG--SSPSHK 512
>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
Length = 505
Score = 402 bits (1034), Expect = e-112
Identities = 233/481 (48%), Positives = 319/481 (66%), Gaps = 37/481 (7%)
Query: 3 RQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASG 62
R F+C S + G +A G S +GL+GGFGS S+ GG R A
Sbjct: 10 RAFSCISACGPRPGRCCITAAPYRGISCY-----RGLTGGFGSHSV--CGGFR----AGS 58
Query: 63 SGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPE 122
G+S GY R+ G G P C T V+VNESLL PLN+E+DP
Sbjct: 59 CGRSFGY-----RSGGVCGP-------SPPCITT--------VSVNESLLTPLNLEIDPN 98
Query: 123 IQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILE 182
Q V+ +E+EQIK+LN++FA+FIDKVRFLEQQN++LETK + Q + C++NLEP+ E
Sbjct: 99 AQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFE 156
Query: 183 GYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVD 242
GYI LR++ E + D RL SEL +V++V+E YKK+YEEE++ R AENEFV LKKDVD
Sbjct: 157 GYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVD 216
Query: 243 AAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIID 302
AY K +L+A VE++ QEI F R L+E EI +QSHISD SV++ +DN+R+L++D II
Sbjct: 217 CAYLRKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIA 276
Query: 303 EVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEI 362
E++ QY++I +S+AEAE+ Y++K +E++ RHG+ L+ TK EI+EL R+IQR+ +E+
Sbjct: 277 EIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEV 336
Query: 363 ENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLK 422
EN K Q S LE A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+M+ K
Sbjct: 337 ENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSK 396
Query: 423 LALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGSVYGFRPSMVSGGYVANSSN 482
L LD+EIATYR+LLE EE R+ E V++ +SS+ GG V G VSG S
Sbjct: 397 LGLDIEIATYRRLLEGEEQRLC-EGIGAVNV-CVSSSRGGVVCG--DLCVSGSRPVTGSV 452
Query: 483 C 483
C
Sbjct: 453 C 453
>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 486
Score = 402 bits (1033), Expect = e-112
Identities = 228/464 (49%), Positives = 314/464 (67%), Gaps = 35/464 (7%)
Query: 3 RQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASG 62
R F+C S + G +A G S +GL+GGFGS S+ GG R A
Sbjct: 10 RAFSCISACGPRPGRCCITAAPYRGISCY-----RGLTGGFGSHSV--CGGFR----AGS 58
Query: 63 SGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPE 122
G+S GY R+ G G P C T V+VNESLL PLN+E+DP
Sbjct: 59 CGRSFGY-----RSGGVCGP-------SPPCITT--------VSVNESLLTPLNLEIDPN 98
Query: 123 IQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILE 182
Q V+ +E+EQIK+LN++FA+FIDKVRFLEQQN++LETK + Q + C++NLEP+ E
Sbjct: 99 AQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFE 156
Query: 183 GYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVD 242
GYI LR++ E + D RL SEL +V++V+E YKK+YEEE++ R AENEFV LKKDVD
Sbjct: 157 GYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVD 216
Query: 243 AAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIID 302
AY K +L+A VE++ QEI F R L+E EI +QSHISD SV++ +DN+R+L++D II
Sbjct: 217 CAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIA 276
Query: 303 EVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEI 362
E++ QY++I +S+AEAE+ Y++K +E++ RHG+ L+ TK EI+EL R+IQR+ +E+
Sbjct: 277 EIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEV 336
Query: 363 ENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLK 422
EN K Q S LE A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+M+ K
Sbjct: 337 ENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSK 396
Query: 423 LALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGSVYG 466
L LD+EIATYR+LLE EE R+ E V++ +SS+ GG V G
Sbjct: 397 LGLDIEIATYRRLLEGEEQRLC-EGVGSVNV-CVSSSRGGVVCG 438
>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 486
Score = 402 bits (1033), Expect = e-112
Identities = 228/464 (49%), Positives = 314/464 (67%), Gaps = 35/464 (7%)
Query: 3 RQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASG 62
R F+C S + G +A G S +GL+GGFGS S+ GG R A
Sbjct: 10 RAFSCISACGPRPGRCCITAAPYRGISCY-----RGLTGGFGSHSV--CGGFR----AGS 58
Query: 63 SGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPE 122
G+S GY R+ G G P C T V+VNESLL PLN+E+DP
Sbjct: 59 CGRSFGY-----RSGGVCGP-------SPPCITT--------VSVNESLLTPLNLEIDPN 98
Query: 123 IQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILE 182
Q V+ +E+EQIK+LN++FA+FIDKVRFLEQQN++LETK + Q + C++NLEP+ E
Sbjct: 99 AQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFE 156
Query: 183 GYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVD 242
GYI LR++ E + D RL SEL +V++V+E YKK+YEEE++ R AENEFV LKKDVD
Sbjct: 157 GYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVD 216
Query: 243 AAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIID 302
AY K +L+A VE++ QEI F R L+E EI +QSHISD SV++ +DN+R+L++D II
Sbjct: 217 CAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIA 276
Query: 303 EVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEI 362
E++ QY++I +S+AEAE+ Y++K +E++ RHG+ L+ TK EI+EL R+IQR+ +E+
Sbjct: 277 EIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEV 336
Query: 363 ENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLK 422
EN K Q S LE A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+M+ K
Sbjct: 337 ENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSK 396
Query: 423 LALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGSVYG 466
L LD+EIATYR+LLE EE R+ E V++ +SS+ GG V G
Sbjct: 397 LGLDIEIATYRRLLEGEEQRLC-EGVGSVNV-CVSSSRGGVVCG 438
>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
sapiens]
Length = 486
Score = 402 bits (1033), Expect = e-112
Identities = 228/464 (49%), Positives = 314/464 (67%), Gaps = 35/464 (7%)
Query: 3 RQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASG 62
R F+C S + G +A G S +GL+GGFGS S+ GG R A
Sbjct: 10 RAFSCISACGPRPGRCCITAAPYRGISCY-----RGLTGGFGSHSV--CGGFR----AGS 58
Query: 63 SGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPE 122
G+S GY R+ G G P C T V+VNESLL PLN+E+DP
Sbjct: 59 CGRSFGY-----RSGGVCGP-------SPPCITT--------VSVNESLLTPLNLEIDPN 98
Query: 123 IQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILE 182
Q V+ +E+EQIK+LN++FA+FIDKVRFLEQQN++LETK + Q + C++NLEP+ E
Sbjct: 99 AQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFE 156
Query: 183 GYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVD 242
GYI LR++ E + D RL SEL +V++V+E YKK+YEEE++ R AENEFV LKKDVD
Sbjct: 157 GYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVD 216
Query: 243 AAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIID 302
AY K +L+A VE++ QEI F R L+E EI +QSHISD SV++ +DN+R+L++D II
Sbjct: 217 CAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIA 276
Query: 303 EVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEI 362
E++ QY++I +S+AEAE+ Y++K +E++ RHG+ L+ TK EI+EL R+IQR+ +E+
Sbjct: 277 EIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEV 336
Query: 363 ENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLK 422
EN K Q S LE A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+M+ K
Sbjct: 337 ENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSK 396
Query: 423 LALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGSVYG 466
L LD+EIATYR+LLE EE R+ E V++ +SS+ GG V G
Sbjct: 397 LGLDIEIATYRRLLEGEEQRLC-EGVGSVNV-CVSSSRGGVVCG 438
>gi|14318422 keratin 86 [Homo sapiens]
Length = 486
Score = 402 bits (1033), Expect = e-112
Identities = 228/464 (49%), Positives = 314/464 (67%), Gaps = 35/464 (7%)
Query: 3 RQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASG 62
R F+C S + G +A G S +GL+GGFGS S+ GG R A
Sbjct: 10 RAFSCISACGPRPGRCCITAAPYRGISCY-----RGLTGGFGSHSV--CGGFR----AGS 58
Query: 63 SGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPE 122
G+S GY R+ G G P C T V+VNESLL PLN+E+DP
Sbjct: 59 CGRSFGY-----RSGGVCGP-------SPPCITT--------VSVNESLLTPLNLEIDPN 98
Query: 123 IQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILE 182
Q V+ +E+EQIK+LN++FA+FIDKVRFLEQQN++LETK + Q + C++NLEP+ E
Sbjct: 99 AQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFE 156
Query: 183 GYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVD 242
GYI LR++ E + D RL SEL +V++V+E YKK+YEEE++ R AENEFV LKKDVD
Sbjct: 157 GYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVD 216
Query: 243 AAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIID 302
AY K +L+A VE++ QEI F R L+E EI +QSHISD SV++ +DN+R+L++D II
Sbjct: 217 CAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIA 276
Query: 303 EVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEI 362
E++ QY++I +S+AEAE+ Y++K +E++ RHG+ L+ TK EI+EL R+IQR+ +E+
Sbjct: 277 EIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEV 336
Query: 363 ENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLK 422
EN K Q S LE A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+M+ K
Sbjct: 337 ENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSK 396
Query: 423 LALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGSVYG 466
L LD+EIATYR+LLE EE R+ E V++ +SS+ GG V G
Sbjct: 397 LGLDIEIATYRRLLEGEEQRLC-EGVGSVNV-CVSSSRGGVVCG 438
>gi|169790841 keratin 83 [Homo sapiens]
Length = 493
Score = 399 bits (1024), Expect = e-111
Identities = 224/447 (50%), Positives = 307/447 (68%), Gaps = 32/447 (7%)
Query: 37 KGLSGGFGSRSLYSLGGVRSLNVASGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTV 96
+GL+GGFGS S+ GG R A G+S GY R+ G G P C T
Sbjct: 44 RGLTGGFGSHSV--CGGFR----AGSCGRSFGY-----RSGGVCGP-------SPPCITT 85
Query: 97 CPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQ 156
V+VNESLL PLN+E+DP Q V+ +E+EQIK+LN++FA+FIDKVRFLEQQN+
Sbjct: 86 --------VSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNK 137
Query: 157 VLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDY 216
+LETK + Q + C++NLEP+ GYI LR++ E + D RL SEL +V++V+E Y
Sbjct: 138 LLETKLQFYQNREC--CQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGY 195
Query: 217 KKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQI 276
KK+YEEE+ R AENEFV LKKDVD AY K +L+A VE++ QEI F R L+E EI +
Sbjct: 196 KKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRIL 255
Query: 277 QSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGR 336
QSHISD SV++ +DN+R+L++D I+ E++ QY++IA +S+AEAE+ Y++K +E++ R
Sbjct: 256 QSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIR 315
Query: 337 HGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDE 396
HG+ L+ TK EI+EL R+IQR+ +E+EN K Q S LE A+A +EQ+G+ AL DAR KL E
Sbjct: 316 HGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAE 375
Query: 397 LEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISII 456
LEGAL +AK+++A ++REYQE+M+ KL LD+EIATYR+LLE EE R+ E V++ +
Sbjct: 376 LEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNV-CV 433
Query: 457 SSTSGGSVYGFRPSMVSGGYVANSSNC 483
SS+ GG V G VSG S C
Sbjct: 434 SSSRGGVVCG--DLCVSGSRPVTGSVC 458
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,808,577
Number of Sequences: 37866
Number of extensions: 803077
Number of successful extensions: 7503
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 251
Number of HSP's successfully gapped in prelim test: 612
Number of HSP's that attempted gapping in prelim test: 4123
Number of HSP's gapped (non-prelim): 2508
length of query: 523
length of database: 18,247,518
effective HSP length: 107
effective length of query: 416
effective length of database: 14,195,856
effective search space: 5905476096
effective search space used: 5905476096
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.