Guide to the Human Genome
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Search of human proteins with 154937340

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154937340 ring finger protein 190 [Homo sapiens]
         (808 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154937342 ring finger protein 190 [Homo sapiens]                  1639   0.0  
gi|154937340 ring finger protein 190 [Homo sapiens]                  1639   0.0  
gi|12383066 axotrophin [Homo sapiens]                                 174   4e-43
gi|33589846 membrane-associated ring finger (C3HC4) 6 [Homo sapi...    62   3e-09
gi|50539414 cellular modulator of immune recognition isoform 7 [...    62   3e-09
gi|50539412 cellular modulator of immune recognition isoform 6 [...    62   3e-09
gi|50539410 cellular modulator of immune recognition isoform 8 [...    62   3e-09
gi|8923613 membrane-associated RING-CH protein I [Homo sapiens]        60   6e-09
gi|53729334 membrane-associated ring finger (C3HC4) 2 isoform 2 ...    54   4e-07
gi|53729332 membrane-associated ring finger (C3HC4) 2 isoform 1 ...    54   4e-07
gi|53729330 membrane-associated ring finger (C3HC4) 2 isoform 1 ...    54   4e-07
gi|30425370 membrane-associated ring finger (C3HC4) 3 [Homo sapi...    49   2e-05
gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo sa...    45   2e-04
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         45   3e-04
gi|148806908 fibronectin type III domain containing 1 [Homo sapi...    44   5e-04
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    44   8e-04
gi|57977325 membrane-associated ring finger (C3HC4) 4 [Homo sapi...    44   8e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        42   0.002
gi|157694494 MYB binding protein 1a isoform 1 [Homo sapiens]           42   0.002
gi|157694492 MYB binding protein 1a isoform 2 [Homo sapiens]           42   0.002
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          40   0.009
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    40   0.009
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre...    40   0.009
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    40   0.009
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    40   0.009
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    40   0.009
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    40   0.009
gi|40255016 membrane-associated RING-CH protein IX [Homo sapiens]      39   0.015
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         39   0.015
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    39   0.025

>gi|154937342 ring finger protein 190 [Homo sapiens]
          Length = 808

 Score = 1639 bits (4243), Expect = 0.0
 Identities = 808/808 (100%), Positives = 808/808 (100%)

Query: 1   MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS 60
           MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
Sbjct: 1   MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS 60

Query: 61  RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV 120
           RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
Sbjct: 61  RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV 120

Query: 121 DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ 180
           DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
Sbjct: 121 DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ 180

Query: 181 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ 240
           VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
Sbjct: 181 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ 240

Query: 241 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC 300
           GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
Sbjct: 241 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC 300

Query: 301 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM 360
           LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
Sbjct: 301 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM 360

Query: 361 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV 420
           EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
Sbjct: 361 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV 420

Query: 421 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA 480
           WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
Sbjct: 421 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA 480

Query: 481 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA 540
           LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
Sbjct: 481 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA 540

Query: 541 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP 600
           VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
Sbjct: 541 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP 600

Query: 601 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR 660
           FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
Sbjct: 601 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR 660

Query: 661 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV 720
           ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
Sbjct: 661 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV 720

Query: 721 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN 780
           DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN
Sbjct: 721 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN 780

Query: 781 YPQPRTEENENSELGDGNEGSISQSQVV 808
           YPQPRTEENENSELGDGNEGSISQSQVV
Sbjct: 781 YPQPRTEENENSELGDGNEGSISQSQVV 808


>gi|154937340 ring finger protein 190 [Homo sapiens]
          Length = 808

 Score = 1639 bits (4243), Expect = 0.0
 Identities = 808/808 (100%), Positives = 808/808 (100%)

Query: 1   MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS 60
           MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS
Sbjct: 1   MLHDARDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS 60

Query: 61  RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV 120
           RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV
Sbjct: 61  RFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKV 120

Query: 121 DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ 180
           DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ
Sbjct: 121 DPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQ 180

Query: 181 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ 240
           VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ
Sbjct: 181 VVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQ 240

Query: 241 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC 300
           GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC
Sbjct: 241 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC 300

Query: 301 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM 360
           LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM
Sbjct: 301 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM 360

Query: 361 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV 420
           EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV
Sbjct: 361 EPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENV 420

Query: 421 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA 480
           WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA
Sbjct: 421 WSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSA 480

Query: 481 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA 540
           LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA
Sbjct: 481 LRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFA 540

Query: 541 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP 600
           VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP
Sbjct: 541 VREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTP 600

Query: 601 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR 660
           FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR
Sbjct: 601 FTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCR 660

Query: 661 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV 720
           ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV
Sbjct: 661 ICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV 720

Query: 721 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN 780
           DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN
Sbjct: 721 DLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERERLSRN 780

Query: 781 YPQPRTEENENSELGDGNEGSISQSQVV 808
           YPQPRTEENENSELGDGNEGSISQSQVV
Sbjct: 781 YPQPRTEENENSELGDGNEGSISQSQVV 808


>gi|12383066 axotrophin [Homo sapiens]
          Length = 704

 Score =  174 bits (440), Expect = 4e-43
 Identities = 91/187 (48%), Positives = 129/187 (68%), Gaps = 9/187 (4%)

Query: 620 AASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEE-GDLCRICQIAGGSPSNPLLEPCG 678
           +A G +D+ +++  + DPE+L+K++ESLL EDSEEE GDLCRICQ+A  S SN L+EPC 
Sbjct: 513 SADGKSDKTKSAPSR-DPERLQKIKESLLLEDSEEEEGDLCRICQMAAASSSNLLIEPCK 571

Query: 679 CVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLVDLGDFNMIEFYQKHQQSQ 738
           C GSLQ+VHQ+C+KKWL+ KI SG+ L AV TCE+CK+ L ++L DF++ E ++ H   Q
Sbjct: 572 CTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELCKEKLELNLEDFDIHELHRAHANEQ 631

Query: 739 AQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERER-------LSRNYPQPRTEENEN 791
           A+ E ++SGLYLV+LLHL EQ F+++M   +    R R       L  +     T E+++
Sbjct: 632 AEYEFISSGLYLVVLLHLCEQSFSDMMGNTNEPSTRVRFINLARTLQAHMEDLETSEDDS 691

Query: 792 SELGDGN 798
            E GD N
Sbjct: 692 EEDGDHN 698


>gi|33589846 membrane-associated ring finger (C3HC4) 6 [Homo
           sapiens]
          Length = 910

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 29/65 (44%), Positives = 41/65 (63%), Gaps = 10/65 (15%)

Query: 651 DSEEEGDLCRICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKT 710
           D+ EE D+CR+C+ + G+P  PL  PC C GS++F+HQECL +WLK            + 
Sbjct: 2   DTAEE-DICRVCR-SEGTPEKPLYHPCVCTGSIKFIHQECLVQWLK--------HSRKEY 51

Query: 711 CEMCK 715
           CE+CK
Sbjct: 52  CELCK 56


>gi|50539414 cellular modulator of immune recognition isoform 7
           [Homo sapiens]
          Length = 291

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 32/98 (32%), Positives = 52/98 (53%), Gaps = 9/98 (9%)

Query: 657 DLCRICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQ 716
           D+CRIC   G   S PL+ PC C GSL FVHQ CL++W+K   T        + CE+CK 
Sbjct: 78  DICRICHCEGDDES-PLITPCHCTGSLHFVHQACLQQWIKSSDT--------RCCELCKY 128

Query: 717 GLLVDLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLL 754
             +++     + ++ +    S  + ++M S  + V+ +
Sbjct: 129 EFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAI 166


>gi|50539412 cellular modulator of immune recognition isoform 6
           [Homo sapiens]
          Length = 291

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 32/98 (32%), Positives = 52/98 (53%), Gaps = 9/98 (9%)

Query: 657 DLCRICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQ 716
           D+CRIC   G   S PL+ PC C GSL FVHQ CL++W+K   T        + CE+CK 
Sbjct: 78  DICRICHCEGDDES-PLITPCHCTGSLHFVHQACLQQWIKSSDT--------RCCELCKY 128

Query: 717 GLLVDLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLL 754
             +++     + ++ +    S  + ++M S  + V+ +
Sbjct: 129 EFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAI 166


>gi|50539410 cellular modulator of immune recognition isoform 8
           [Homo sapiens]
          Length = 291

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 32/98 (32%), Positives = 52/98 (53%), Gaps = 9/98 (9%)

Query: 657 DLCRICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQ 716
           D+CRIC   G   S PL+ PC C GSL FVHQ CL++W+K   T        + CE+CK 
Sbjct: 78  DICRICHCEGDDES-PLITPCHCTGSLHFVHQACLQQWIKSSDT--------RCCELCKY 128

Query: 717 GLLVDLGDFNMIEFYQKHQQSQAQNELMNSGLYLVLLL 754
             +++     + ++ +    S  + ++M S  + V+ +
Sbjct: 129 EFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAI 166


>gi|8923613 membrane-associated RING-CH protein I [Homo sapiens]
          Length = 272

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 27/65 (41%), Positives = 38/65 (58%), Gaps = 9/65 (13%)

Query: 657 DLCRICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQ 716
           D+CRIC   G   S PL+ PC C G+L+FVHQ CL +W+K   T        + CE+CK 
Sbjct: 61  DICRICHCEGDEES-PLITPCRCTGTLRFVHQSCLHQWIKSSDT--------RCCELCKY 111

Query: 717 GLLVD 721
             +++
Sbjct: 112 DFIME 116


>gi|53729334 membrane-associated ring finger (C3HC4) 2 isoform 2
           [Homo sapiens]
          Length = 176

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 10/71 (14%)

Query: 651 DSEEEGDLCRICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKT 710
           D+  +G  CRIC    G+    LL PCGC G+L  VH+ CL+KWL    TS         
Sbjct: 56  DTPSDGPFCRICH--EGANGECLLSPCGCTGTLGAVHKSCLEKWLSSSNTS--------Y 105

Query: 711 CEMCKQGLLVD 721
           CE+C     V+
Sbjct: 106 CELCHTEFAVE 116


>gi|53729332 membrane-associated ring finger (C3HC4) 2 isoform 1
           [Homo sapiens]
          Length = 246

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 10/71 (14%)

Query: 651 DSEEEGDLCRICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKT 710
           D+  +G  CRIC    G+    LL PCGC G+L  VH+ CL+KWL    TS         
Sbjct: 56  DTPSDGPFCRICH--EGANGECLLSPCGCTGTLGAVHKSCLEKWLSSSNTS--------Y 105

Query: 711 CEMCKQGLLVD 721
           CE+C     V+
Sbjct: 106 CELCHTEFAVE 116


>gi|53729330 membrane-associated ring finger (C3HC4) 2 isoform 1
           [Homo sapiens]
          Length = 246

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 10/71 (14%)

Query: 651 DSEEEGDLCRICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKT 710
           D+  +G  CRIC    G+    LL PCGC G+L  VH+ CL+KWL    TS         
Sbjct: 56  DTPSDGPFCRICH--EGANGECLLSPCGCTGTLGAVHKSCLEKWLSSSNTS--------Y 105

Query: 711 CEMCKQGLLVD 721
           CE+C     V+
Sbjct: 106 CELCHTEFAVE 116


>gi|30425370 membrane-associated ring finger (C3HC4) 3 [Homo
           sapiens]
          Length = 253

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 10/79 (12%)

Query: 636 DPEKLKKLQESLLEEDSEEEGDLCRICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWL 695
           D + L  +  +L  +    +  +CRIC    GS    LL PC C G+L  +H+ CL+ WL
Sbjct: 48  DGQLLSTVVRTLATQSPFNDRPMCRICH--EGSSQEDLLSPCECTGTLGTIHRSCLEHWL 105

Query: 696 KVKITSGADLGAVKTCEMC 714
               TS         CE+C
Sbjct: 106 SSSNTS--------YCELC 116


>gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo
           sapiens]
          Length = 402

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 26/99 (26%), Positives = 40/99 (40%), Gaps = 10/99 (10%)

Query: 616 GSRMAASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEEGDLCRICQIAGGSPSNPLLE 675
           G      G  D+ ET  + +         +       +    +C+IC    G+    LL 
Sbjct: 127 GGERERRGAGDQPETRSVCSSRSSSSGGGDQRAGHQHQHHQPICKIC--FQGAEQGELLN 184

Query: 676 PCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMC 714
           PC C GS+++ HQ CL KW+  +           TCE+C
Sbjct: 185 PCRCDGSVRYTHQLCLLKWISER--------GSWTCELC 215


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 87/416 (20%), Positives = 150/416 (36%), Gaps = 60/416 (14%)

Query: 6   RDRQKFFSDVQYLRDMQHKVDSEYQACLRRQEYRR------DPNEKKRDQFWGQETSFER 59
           RDR++     +  R+ +H+ D E Q   R++E+ R      + + + RD+   +E   E+
Sbjct: 423 RDRERERRQREREREREHERDKERQR--RKEEWERERAKRDEKDRQHRDRDREKEREKEK 480

Query: 60  SRFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEK 119
            +   RS    S   E    E  ++        + K P     S K+K   +++  +A +
Sbjct: 481 GKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARR 540

Query: 120 VDPSEPSPADQAPMVLLRKRKPNL--------RRFTVSPESHSPRA------SGDRSRQK 165
              +  S A  +       R  +         R  + S  S+S R+      SG RSR +
Sbjct: 541 RRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSR 600

Query: 166 --QQWPAKVPVPRGADQVVQQEGLMCNTKLKRPNQERRNLVPSSQP-----MTENAPDRA 218
                P+  P P      ++ +G       K   +  +   P   P      T   P+  
Sbjct: 601 SFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPT 660

Query: 219 KKGDPSAPSQSE---LHPALSQAFQGKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDED 275
           K GDP    + E     P   +   G  S    S +SG             +S R R   
Sbjct: 661 KPGDPREARRKERPARTPPRRRTLSGSGSGSG-SSYSG-------------SSSRSRSLS 706

Query: 276 FYSILSLNSRRESDDTEEETQSEECLWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEEN 335
             S+ S++S   S  +     SE+ ++  + SP S +  +      T   + K+K  +  
Sbjct: 707 VSSVSSVSSATSSSSSAHSVDSED-MYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGV 765

Query: 336 AENCRGHSSRRSEPSHGSLRISNAMEPATERPSAGQRLSQDPGLPDRESATEKDRG 391
            E  R              R S+   P + +P AG + SQ P  P +    +  +G
Sbjct: 766 KEEKR-------------KRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQG 808


>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
          Length = 1894

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 65/277 (23%), Positives = 107/277 (38%), Gaps = 44/277 (15%)

Query: 151  ESHSPRASGDRSRQKQQWPAKVPVPRGADQVVQQEGLMCNTKLKRPNQERRNLVPSSQPM 210
            E HSP+A    S  +   PA+ P  R          +   T  + P Q+    V +SQ  
Sbjct: 961  EGHSPKAQPG-STDRHASPARPPAARSQQHPSVPRRM---TPGRAPQQQPPPPVATSQ-- 1014

Query: 211  TENAPDRAKKGDPSAPSQSELHPALSQAFQGKNSPQVLSEFSGPPLTPTTVGGPRKASFR 270
              + P    +    +PSQ  L  +L+QA + + + Q  S  S  P T ++  G    + +
Sbjct: 1015 --HHPGPQSRDAGRSPSQPRL--SLTQAGRPRPTSQGRSHSSSDPYTASS-RGMLPTALQ 1069

Query: 271  FRDEDFYSILSLNSRRESDDTEEETQSEECLWVGVRSPCSPSHHKRSRFGGTSTPQAKNK 330
             +DED           + D TE E Q             +P+H  R++    S P+ +  
Sbjct: 1070 NQDED------AQGSYDDDSTEVEAQDVR----------APAHAARAKEAAASLPKHQQV 1113

Query: 331  NFEENA------ENCRGHSSRRSEPSHGSLRISNAMEPATERPSAGQRLSQDP-GLPDRE 383
                 A       + RGH++  + PS      S A  P+   P   +  S+ P     ++
Sbjct: 1114 ESPTGAGAGGDHRSQRGHAASPARPSRPGGPQSRARVPSRAAPGKSEPPSKRPLSSKSQQ 1173

Query: 384  SATEKD---------RGGSENAKKSPL-SWDTKSEPR 410
            S + +D         +GG E+   S +  W + S PR
Sbjct: 1174 SVSAEDDEEEDAGFFKGGKEDLLSSSVPKWPSSSTPR 1210



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 57/219 (26%), Positives = 89/219 (40%), Gaps = 40/219 (18%)

Query: 203  LVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQGKNSPQVLSEFSGPPLTPTTVG 262
            L PSS P +   P RA    P  PS S+ HP LS    G        E    PL  T V 
Sbjct: 843  LQPSSSPQS-TVPSRAH---PRVPSHSDSHPKLSSGIHG-------DEEDEKPLPATVVN 891

Query: 263  GPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEECLWVGVRSPCSPSHHKRSRFGGT 322
                +S R      +  L  + +R +    +E   E       +S  + +H +    G  
Sbjct: 892  DHVPSSSRQPISRGWEDLRRSPQRGASLHRKEPIPE-----NPKSTGADTHPQ----GKY 942

Query: 323  STPQAKNKNFEENAE-NCRGHSSRRSEPSHGSLRISNAMEPAT---ERPSAGQRLSQDPG 378
            S+  +K ++ +++ + +  GHS  +++P       S A  PA    + PS  +R++  PG
Sbjct: 943  SSLASKAQDVQQSTDADTEGHSP-KAQPGSTDRHASPARPPAARSQQHPSVPRRMT--PG 999

Query: 379  -----LPDRESATEKDRGG--SENAKKSPLSWDTKSEPR 410
                  P    AT +   G  S +A +SP      S+PR
Sbjct: 1000 RAPQQQPPPPVATSQHHPGPQSRDAGRSP------SQPR 1032


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 95/452 (21%), Positives = 158/452 (34%), Gaps = 28/452 (6%)

Query: 206  SSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQGKNSPQVLSEFSGPPLTPTTVGGPR 265
            SS   + N+ D +   D S  S+S      S +    +S    S  S    + ++     
Sbjct: 678  SSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737

Query: 266  KASFRFRDEDFYSILSLNSRRESDDTEEETQSEECLWVGVRSPCSPSHHKRSRFGGTSTP 325
              S    D    S  S +S  +S D+   + S +       S  S S         + + 
Sbjct: 738  SNSSDSSDSSDSSNSSDSS--DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSS 795

Query: 326  QAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAMEPATERPSAGQRLSQDPGLPDRESA 385
             + N +   N+ +    S      S  S   SN+ + +    S+    S D    D   +
Sbjct: 796  DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS--DGSDS 853

Query: 386  TEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAENVWSDCISVEHRPGTHDSEGYWKDYLN 445
               +R  S N+  S  S D+ +              SD     +   + DS        +
Sbjct: 854  DSSNRSDSSNSSDSSDSSDSSNSSDSSDS-------SDSNESSNSSDSSDSSNSSDSDSS 906

Query: 446  SSQNSLDYFISGRPISPRSSVNSSYNPPASFMHSALRDDIPVDLSMSSTSVHSSDSEGNS 505
             S NS D   S        S NSS N  +S   ++       D S SS S +SSDS  +S
Sbjct: 907  DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966

Query: 506  GFHVCQPLSPIRNRTPFASAENHNYFPVNSAHEFAVREAEDTTLTSQPQGAPLYTDLLLN 565
                    S   N +  + + N +    +S+      ++ D++ +S    +   +D   +
Sbjct: 967  D-------SSDSNSSDSSDSSNSS----DSSDSSDSSDSSDSSDSSNSSDSSDSSD--SS 1013

Query: 566  PQGNLSLVDSSSSSPSRMNSEGHLHVSGSLQENTPFTFFAVSHFPNQNDNGSRMAASGFT 625
               N S  DSS+SS S  NS      S S   +        S   N +D+     +S  +
Sbjct: 1014 DSSNSS--DSSNSSDS-SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070

Query: 626  DEKETSKIKADPEKLKKLQESLLEEDSEEEGD 657
            D  ++S   +D  +     +S    DS +  D
Sbjct: 1071 DSSDSSD-SSDSSESSDSSDSSNSSDSSDSSD 1101



 Score = 38.5 bits (88), Expect = 0.025
 Identities = 104/566 (18%), Positives = 186/566 (32%), Gaps = 32/566 (5%)

Query: 56   SFERSRFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVR 115
            S + S  S  S S  SS+  D+     SS    +        + + +       S+ +  
Sbjct: 746  SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805

Query: 116  KAEKVDPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVP 175
             ++  D S+ S +D +          N    + S +S     S D S             
Sbjct: 806  SSDSSDSSDSSDSDSS----------NSSDSSNSSDSSDSSNSSDSSDSSDS-------S 848

Query: 176  RGADQVVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPAL 235
             G+D          N+     + +  N   SS     N  + +   D S  S S    + 
Sbjct: 849  DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSN--ESSNSSDSSDSSNSSDSDSS 906

Query: 236  SQAFQGKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEET 295
              +    +S    S  S      +       +S      D     + +    S D+   +
Sbjct: 907  DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966

Query: 296  QSEECLWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLR 355
             S +          + S    S     S+  + + N  +++++     S  S  S  S  
Sbjct: 967  DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSD 1026

Query: 356  ISNAMEPATERPSAGQRLSQDPG--LPDRESATEKDRGGSENAKKSPLSWDTKSEPRQEV 413
             SN+ + +    S+    S D         S+   D   S ++  S  S D+        
Sbjct: 1027 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSD 1086

Query: 414  GVNAENVWSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISPRSSVNSSYNPP 473
              ++ N      S +    +  S+       + S NS D   S        S NSS +  
Sbjct: 1087 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSD 1146

Query: 474  ASFMHSALRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPFASAENHNYFPV 533
            +S    +       D S SS S  SSDS  +S        S   + +  + + + +    
Sbjct: 1147 SSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS---- 1202

Query: 534  NSAHEFAVREAEDTTLTSQPQGAPLYTDLLLNPQGNLS--LVDSSSSSPSRMNSEGHLHV 591
            +S+      ++ D++ +S    +   +D   +   + S    DSS+SS S  +S+     
Sbjct: 1203 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDST 1262

Query: 592  SGSLQENTPFTFFAVSHFPNQNDNGS 617
            S S  E+      + S   N N+NGS
Sbjct: 1263 SDSNDESD-----SQSKSGNGNNNGS 1283



 Score = 30.8 bits (68), Expect = 5.3
 Identities = 72/375 (19%), Positives = 134/375 (35%), Gaps = 62/375 (16%)

Query: 283 NSRRESDDTEEETQSEECLWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGH 342
           +S  +S D+   + S +       S  S S   +S    + +  + + +  +++++    
Sbjct: 590 SSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSD 649

Query: 343 SSRRSEPSHGSLRISNAMEPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSPLS 402
           SS  S+ S  S   SN+ + +    S+    S D       S+   D   S N+ +S  S
Sbjct: 650 SSDNSDSSDSS-NSSNSSDSSDSSDSSDSSSSSDSS----NSSDSSDSSDSSNSSESSDS 704

Query: 403 WDTKSEPRQEVGVNAENVWSDCISVEHRPGTHDSEGYWKDYLNSSQNSLDYFISGRPISP 462
            D+      +   ++ +  SD                  D  NSS +S            
Sbjct: 705 SDSSDSDSSDSSDSSNSNSSD-----------------SDSSNSSDSS------------ 735

Query: 463 RSSVNSSYNPPASFMHSALRDDIPVDLSMSSTSVHSSDSEGNSGFHVCQPLSPIRNRTPF 522
             S NSS +  +S   ++       D S SS S  SSDS  +S        +   N +  
Sbjct: 736 -DSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS 794

Query: 523 ASAENHNYFPVNSAHEFAVREAEDTTLTSQPQGAPLYTDLLLNPQGNLSLVDSSSSSPSR 582
           + +        NS+      ++ D++ +S    +        N   + +  DSS SS S 
Sbjct: 795 SDSS-------NSSDSSNSSDSSDSSDSSDSDSS--------NSSDSSNSSDSSDSSNSS 839

Query: 583 MNSEGHLHVSGSLQENTPFTFFAVSHFPNQNDNGSRMAASGFTDEKETSKIKADPEKLKK 642
            +S+      GS  +++           N++D+ +   +S  +D   +S   +D     +
Sbjct: 840 DSSDSSDSSDGSDSDSS-----------NRSDSSNSSDSSDSSDSSNSSD-SSDSSDSNE 887

Query: 643 LQESLLEEDSEEEGD 657
              S    DS    D
Sbjct: 888 SSNSSDSSDSSNSSD 902


>gi|57977325 membrane-associated ring finger (C3HC4) 4 [Homo
           sapiens]
          Length = 410

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 24/64 (37%), Positives = 30/64 (46%), Gaps = 10/64 (15%)

Query: 651 DSEEEGDLCRICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKT 710
           DS     LCRIC    G     LL PC C GS++  HQ CL KW+  +           +
Sbjct: 155 DSGMRTPLCRIC--FQGPEQGELLSPCRCDGSVKCTHQPCLIKWISER--------GCWS 204

Query: 711 CEMC 714
           CE+C
Sbjct: 205 CELC 208


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 81/349 (23%), Positives = 119/349 (34%), Gaps = 32/349 (9%)

Query: 65   RSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKVDPSE 124
            RS S  S    +    P+     S    D K  A      + +  S+  +       P E
Sbjct: 1496 RSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQE 1555

Query: 125  PSPADQAPMVLLRKRKP--NLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQVV 182
             S +D +P    + R P     R   SPE  S      R  +    P     PR A +  
Sbjct: 1556 RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRA- 1614

Query: 183  QQEGLMCNTKLKRPNQE---RRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAF 239
             Q G   + + K P      RR+   SS      +P+    G  S  S  E  P    A 
Sbjct: 1615 -QSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE----GSSSTESSPEHPPKSRTAR 1669

Query: 240  QG-KNSPQVLSEFSGPPLTPTTVGGP---RKASFRFRDEDFYSILSLNSRRESDDTEEET 295
            +G ++SP+  ++   PP   ++   P   RKA    R           S   S +T   T
Sbjct: 1670 RGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRS---------RSASSSPETRSRT 1720

Query: 296  QSEECLWVGVRSPCSPSHHKRS--RFGGTSTPQAK--NKNFEENAENCRGHSSRRSEPSH 351
                     V SP  P+   RS  R    S+P+ K  ++     +   RG    RS    
Sbjct: 1721 PPRHRRSPSVSSP-EPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRR 1779

Query: 352  GSLRISNAMEPATERPSAGQRLSQDPGLPDRESATEKDRGGSENAKKSP 400
               R +   + +    S  +R  +      R   T + RGGS    +SP
Sbjct: 1780 EKTRTTRRRDRSGSSQSTSRRRQRS---RSRSRVTRRRRGGSGYHSRSP 1825



 Score = 38.1 bits (87), Expect = 0.033
 Identities = 44/179 (24%), Positives = 66/179 (36%), Gaps = 30/179 (16%)

Query: 42   PNEKKRDQFWGQETSFERSRFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQ 101
            P E  R+    + T  +R R SS SSS  SSS   + +   SS   S+            
Sbjct: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSS------------ 2633

Query: 102  TSVKQKHKSTMTVRKAEKVDPSEPSPADQAPMVLLR----KRKPNLRRFTVSPESHSPRA 157
                    S+ +   +     S PSPA   P  L +    K+ P   R + SP       
Sbjct: 2634 --------SSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSL 2685

Query: 158  SGDRSRQ----KQQWPAKVPVPRGADQVVQQEGLMCNTK--LKRPNQERRNLVPSSQPM 210
               RS      +++ P+  P PR       + G     +   + P+ +RR   PS +PM
Sbjct: 2686 RDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPM 2744



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 71/307 (23%), Positives = 114/307 (37%), Gaps = 43/307 (14%)

Query: 135 LLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQVVQQEGLMCNT--- 191
           L  K+   LR      +S+   +S D  R+ ++     P P     +V++     +    
Sbjct: 127 LNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPK 186

Query: 192 -KLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHPALSQAFQGKNSPQVLSE 250
            K K+  ++R     SS P  E      KK   S  S+S+     S   + K   +    
Sbjct: 187 QKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSE-SESKKRKHRSPTPKSKRKSKDKKR 245

Query: 251 FSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEECLWVGVRSPCS 310
                 TP      R+A      +   S  +  SR  S   +  T +     +  RSP S
Sbjct: 246 KRSRSTTPAPKS--RRAHRSTSADSASSSDTSRSRSRSAAAKTHTTA-----LAGRSP-S 297

Query: 311 PSHHKR-------SRFGGTST-----PQAKNKN----FEENAENCRGHSSRRSEPSHGSL 354
           P+  +R       S  G TST     P+   K     +E+  ++ +  S+ R  PS    
Sbjct: 298 PASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPE-- 355

Query: 355 RISNAMEPATERPSAGQR------------LSQDPGLPDRESATEKDRGGSENAKKSPLS 402
           R S   EP    P   +R            LSQ+P  P  E++  +DR   ++ +K P S
Sbjct: 356 RSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQS 415

Query: 403 WDTKSEP 409
             ++S P
Sbjct: 416 SSSESSP 422



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 33/111 (29%), Positives = 48/111 (43%), Gaps = 8/111 (7%)

Query: 53   QETSFERSRFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTM 112
            Q     RS  SS SSS  SSS   + +   SS   S+    S LP   + ++K+    T 
Sbjct: 2525 QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTP 2584

Query: 113  TVRKAEKVD-PSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRS 162
              ++A +   P EP+PA        RKR+ +    + S  S S  +S   S
Sbjct: 2585 APKEAVREGRPPEPTPAK-------RKRRSSSSSSSSSSSSSSSSSSSSSS 2628



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 63/287 (21%), Positives = 103/287 (35%), Gaps = 34/287 (11%)

Query: 55  TSFERSRFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTV 114
           T   R R  S S  K  S      +   SS ++   +  S+      +S + K KS +++
Sbjct: 717 TPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSR-SLSSPRSKAKSRLSL 775

Query: 115 RKAEKVDPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAK--- 171
           R++       P    Q P    R      +  + +P   S  +S    +QK + P++   
Sbjct: 776 RRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSH 835

Query: 172 ---VPVPRGADQVVQQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPD-RAKKGDPSAPS 227
               P P+       ++G      +  P    +++ P  +   E++PD   K   PS  S
Sbjct: 836 SSSSPHPKVKSGTPPRQG-----SITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHS 890

Query: 228 QS-ELHPALSQAFQGKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRR 286
            S    P +  +   + SP   S  S P      +  PR+ S         S     SR 
Sbjct: 891 CSGSSPPRVKSSTPPRQSP---SRSSSPQPKVKAIISPRQRSHS------GSSSPSPSRV 941

Query: 287 ESDDTEEETQSEECLWVGVRSPCSPSHHK---RSRFGGTSTPQAKNK 330
            S  T   ++S         SPCS    +   R    G+S+P  K K
Sbjct: 942 TSRTTPRRSRSV--------SPCSNVESRLLPRYSHSGSSSPDTKVK 980


>gi|157694494 MYB binding protein 1a isoform 1 [Homo sapiens]
          Length = 1332

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 28/154 (18%)

Query: 116  KAEKVDPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVP 175
            K EK D  E   A Q+P+   RK+K  L      PE+        + R+K+         
Sbjct: 1148 KLEKKDAKEIPSATQSPISKKRKKKGFL------PET--------KKRKKR--------- 1184

Query: 176  RGADQVVQQEGLMCNTKLKRP---NQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELH 232
            +  D    ++G    T   +P    +++RN   +  P   N     K   P AP++S   
Sbjct: 1185 KSEDGTPAEDGTPAATGGSQPPSMGRKKRNRTKAKVPAQANGTPTTKSPAPGAPTRSPST 1244

Query: 233  PALSQAFQGKNSPQVLSEFSGPPLTPTTVGGPRK 266
            PA S   Q KN  Q  S+ +G P +PT   G ++
Sbjct: 1245 PAKSPKLQKKN--QKPSQVNGAPGSPTEPAGQKQ 1276


>gi|157694492 MYB binding protein 1a isoform 2 [Homo sapiens]
          Length = 1328

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 28/154 (18%)

Query: 116  KAEKVDPSEPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVP 175
            K EK D  E   A Q+P+   RK+K  L      PE+        + R+K+         
Sbjct: 1148 KLEKKDAKEIPSATQSPISKKRKKKGFL------PET--------KKRKKR--------- 1184

Query: 176  RGADQVVQQEGLMCNTKLKRP---NQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELH 232
            +  D    ++G    T   +P    +++RN   +  P   N     K   P AP++S   
Sbjct: 1185 KSEDGTPAEDGTPAATGGSQPPSMGRKKRNRTKAKVPAQANGTPTTKSPAPGAPTRSPST 1244

Query: 233  PALSQAFQGKNSPQVLSEFSGPPLTPTTVGGPRK 266
            PA S   Q KN  Q  S+ +G P +PT   G ++
Sbjct: 1245 PAKSPKLQKKN--QKPSQVNGAPGSPTEPAGQKQ 1276


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 84/394 (21%), Positives = 143/394 (36%), Gaps = 42/394 (10%)

Query: 34  RRQEYRRDPNEKKRDQFWGQETSFERSRFSSRSSSKQSSSEEDALTEPRSSIKISAFKCD 93
           + Q   R P  + R   W +  S ERS   SRSSSK+   +    + PR     S     
Sbjct: 339 KSQNQSRTPR-RGRSHNWSRNPSKERSHSHSRSSSKE--RDHRGSSSPRKESGRSQSGSP 395

Query: 94  SKLPAIDQTSVKQKHKSTMTVRKAEKVDPSEPSPADQAPMVLLRKRKPNLRRFTVSPESH 153
           +K     ++    K +     R   K      S +        R R P   R      S 
Sbjct: 396 NKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKAR--DRSRSR 453

Query: 154 SPRASGDRSRQKQQWPAKVPVPRGADQVVQQEGLMCNTKLKRPNQE---RRNLVPSSQPM 210
           SP  + D SR +    A+    R   +   +E    +++L  P++E   RR+  PS +  
Sbjct: 454 SPNKARDHSRSRSPNKAR---DRSRSRSPSKE--RDHSQLGSPSKERDHRRSRSPSKERQ 508

Query: 211 TENAPDRAKKGDPSAPSQSELHPALSQAFQGKNSPQVLSEFSGPPLTPTTVGGPRKASFR 270
              +   +K+ D     +    P+  +  +   SP    + S    +P+     R++   
Sbjct: 509 CRQSRSSSKERD----HRRSRSPSKERQRRQSRSPNKERDRS-QSRSPSEEREHRQSRSP 563

Query: 271 FRDEDFYSILSLNSRRESDDTEEETQSEECLWVGVRSPCSPSHHKRSRFGGTSTPQAKNK 330
            ++ D     S +  RE    +  + SEE      RSP   S + R R        ++++
Sbjct: 564 SKERDRRRWRSPSKERER--RQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSR 621

Query: 331 NFEENAENCRGH-SSRRSEPSHGSL-----------RISNAMEPATER----------PS 368
              +   + +   SS+ S+PS  ++           R S+  +  T            PS
Sbjct: 622 TPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPS 681

Query: 369 AGQRLSQDPGLPDRESATEKDRGGSENAKKSPLS 402
            GQ LSQD    D  ++     G   ++  S L+
Sbjct: 682 GGQTLSQDDSQADATTSKATLPGERSSSSSSKLA 715


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 78/371 (21%), Positives = 131/371 (35%), Gaps = 53/371 (14%)

Query: 40  RDPNEKKRDQFWGQETSFERSRFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAI 99
           +D  E    +    E S +  + S  S+ +   S +D  +E R        + DSK    
Sbjct: 124 KDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNED--RVDSKPEGG 181

Query: 100 DQTSVKQKHKSTMTVRKAEKVDPSEPSPADQAPMVL-----LRKRKPNLRRFTVSPESHS 154
           D T   +  +  +      +    + S  D   M       +R  + N R  +   +S  
Sbjct: 182 DSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKS-- 239

Query: 155 PRASGDRSRQKQQWPAKVPVPRGADQVVQQEGLMCNTKLKRPNQERRNLVPSSQPM---- 210
            + SG+ S Q     +      G  Q+++        K +   ++ R+ +  +  M    
Sbjct: 240 -KESGENSEQANTQDS------GGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVK 292

Query: 211 ---TENA---------PDRAKKGDPSAPSQSELHPALSQAFQGKNSP------------- 245
              TEN+         P R  KGD    S+  L    SQ   G +S              
Sbjct: 293 SDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENS 352

Query: 246 -----QVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC 300
                +V+SE  G    PTT     +      +ED    LS +S+ ES + + +++S E 
Sbjct: 353 SESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLS-HSKSESREEQADSESSES 411

Query: 301 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM 360
           L     SP SP     S   G  +  +  ++  E + +    S   S+ S  S   SN+ 
Sbjct: 412 LNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSD--SQDSSRSKEDSNST 469

Query: 361 EPATERPSAGQ 371
           E  +     GQ
Sbjct: 470 ESKSSSEEDGQ 480


>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
           precursor [Homo sapiens]
          Length = 497

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 78/371 (21%), Positives = 131/371 (35%), Gaps = 53/371 (14%)

Query: 40  RDPNEKKRDQFWGQETSFERSRFSSRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAI 99
           +D  E    +    E S +  + S  S+ +   S +D  +E R        + DSK    
Sbjct: 108 KDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNED--RVDSKPEGG 165

Query: 100 DQTSVKQKHKSTMTVRKAEKVDPSEPSPADQAPMVL-----LRKRKPNLRRFTVSPESHS 154
           D T   +  +  +      +    + S  D   M       +R  + N R  +   +S  
Sbjct: 166 DSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKS-- 223

Query: 155 PRASGDRSRQKQQWPAKVPVPRGADQVVQQEGLMCNTKLKRPNQERRNLVPSSQPM---- 210
            + SG+ S Q     +      G  Q+++        K +   ++ R+ +  +  M    
Sbjct: 224 -KESGENSEQANTQDS------GGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVK 276

Query: 211 ---TENA---------PDRAKKGDPSAPSQSELHPALSQAFQGKNSP------------- 245
              TEN+         P R  KGD    S+  L    SQ   G +S              
Sbjct: 277 SDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENS 336

Query: 246 -----QVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC 300
                +V+SE  G    PTT     +      +ED    LS +S+ ES + + +++S E 
Sbjct: 337 SESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLS-HSKSESREEQADSESSES 395

Query: 301 LWVGVRSPCSPSHHKRSRFGGTSTPQAKNKNFEENAENCRGHSSRRSEPSHGSLRISNAM 360
           L     SP SP     S   G  +  +  ++  E + +    S   S+ S  S   SN+ 
Sbjct: 396 LNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSD--SQDSSRSKEDSNST 453

Query: 361 EPATERPSAGQ 371
           E  +     GQ
Sbjct: 454 ESKSSSEEDGQ 464


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 96/400 (24%), Positives = 143/400 (35%), Gaps = 81/400 (20%)

Query: 64  SRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKVDPS 123
           S SS + S SEE+A    RS +K S      K+  +   S   K     T  K      +
Sbjct: 270 SESSEEGSESEEEAPAGTRSQVKAS-----EKILQVRAASAPAKG----TPGKG-----A 315

Query: 124 EPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPA-KVPVPRGADQVV 182
            P+P  +A  V  + +          PE  S  +S + S  +++ PA K  +   A    
Sbjct: 316 TPAPPGKAGAVASQTKAGK-------PEEDSESSSEESSDSEEETPAAKALLQAKASGKT 368

Query: 183 QQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHP------ALS 236
            Q G       + P   R+   P+    T  A  +A+ G     SQS          A +
Sbjct: 369 SQVGAASAPAKESP---RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA 425

Query: 237 QAFQGKNSPQVL--------SEFSGPPLTPTTVGGPRKASFRF--RDEDFYSILSLNSRR 286
           QA     +PQV         S   G    P    GP  A  +   ++ED     S +S  
Sbjct: 426 QAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEED-----SRSSSE 480

Query: 287 ESDDTEEETQSEECLWVGVRSPCSPSHHKRSRFG----------------GTSTPQAKNK 330
           ESD   E   +     V      SP     S  G                G +TP A+  
Sbjct: 481 ESDSDREALAAMNAAQVKPLGK-SPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 539

Query: 331 NFEENAENCRGHSSRRSEPSHGSLRISNAMEPATERPSAGQRLSQDP------GLPDR-- 382
            +EE++E+    SS  S+       +  A+ PA E+ S G  L   P      G P +  
Sbjct: 540 KWEEDSESSSEESSDSSDG-----EVPTAVAPAQEK-SLGNILQAKPTSSPAKGPPQKAG 593

Query: 383 ----ESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAE 418
               +   EK    SE++++S  S D++  P       A+
Sbjct: 594 PVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAK 633



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 59/252 (23%), Positives = 91/252 (36%), Gaps = 45/252 (17%)

Query: 66  SSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKVDPSEP 125
           S+S+ S  EE+A  E   +    A    S L A   +S+K+K K+     KA K   S P
Sbjct: 83  STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKA--ETEKAGKTGNSMP 140

Query: 126 SPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQVVQQE 185
            PA    +  L   K             SPR S + S                 +  ++ 
Sbjct: 141 HPATGKTVANLLSGK-------------SPRKSAEPSANTTL----------VSETEEEG 177

Query: 186 GLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAK-KGDPSA-PSQ---SELHPALSQAFQ 240
            +       +P         SS   T ++ D    +G PS  P+Q   S +    S A +
Sbjct: 178 SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARK 237

Query: 241 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC 300
              +P  + +     +TP   GG    + R +  +           ES+ +EE ++SEE 
Sbjct: 238 AAPAPGKVGD-----VTPQVKGGALPPAKRAKKPE----------EESESSEEGSESEEE 282

Query: 301 LWVGVRSPCSPS 312
              G RS    S
Sbjct: 283 APAGTRSQVKAS 294


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 96/400 (24%), Positives = 143/400 (35%), Gaps = 81/400 (20%)

Query: 64  SRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKVDPS 123
           S SS + S SEE+A    RS +K S      K+  +   S   K     T  K      +
Sbjct: 270 SESSEEGSESEEEAPAGTRSQVKAS-----EKILQVRAASAPAKG----TPGKG-----A 315

Query: 124 EPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPA-KVPVPRGADQVV 182
            P+P  +A  V  + +          PE  S  +S + S  +++ PA K  +   A    
Sbjct: 316 TPAPPGKAGAVASQTKAGK-------PEEDSESSSEESSDSEEETPAAKALLQAKASGKT 368

Query: 183 QQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHP------ALS 236
            Q G       + P   R+   P+    T  A  +A+ G     SQS          A +
Sbjct: 369 SQVGAASAPAKESP---RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA 425

Query: 237 QAFQGKNSPQVL--------SEFSGPPLTPTTVGGPRKASFRF--RDEDFYSILSLNSRR 286
           QA     +PQV         S   G    P    GP  A  +   ++ED     S +S  
Sbjct: 426 QAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEED-----SRSSSE 480

Query: 287 ESDDTEEETQSEECLWVGVRSPCSPSHHKRSRFG----------------GTSTPQAKNK 330
           ESD   E   +     V      SP     S  G                G +TP A+  
Sbjct: 481 ESDSDREALAAMNAAQVKPLGK-SPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 539

Query: 331 NFEENAENCRGHSSRRSEPSHGSLRISNAMEPATERPSAGQRLSQDP------GLPDR-- 382
            +EE++E+    SS  S+       +  A+ PA E+ S G  L   P      G P +  
Sbjct: 540 KWEEDSESSSEESSDSSDG-----EVPTAVAPAQEK-SLGNILQAKPTSSPAKGPPQKAG 593

Query: 383 ----ESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAE 418
               +   EK    SE++++S  S D++  P       A+
Sbjct: 594 PVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAK 633



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 59/252 (23%), Positives = 91/252 (36%), Gaps = 45/252 (17%)

Query: 66  SSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKVDPSEP 125
           S+S+ S  EE+A  E   +    A    S L A   +S+K+K K+     KA K   S P
Sbjct: 83  STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKA--ETEKAGKTGNSMP 140

Query: 126 SPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQVVQQE 185
            PA    +  L   K             SPR S + S                 +  ++ 
Sbjct: 141 HPATGKTVANLLSGK-------------SPRKSAEPSANTTL----------VSETEEEG 177

Query: 186 GLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAK-KGDPSA-PSQ---SELHPALSQAFQ 240
            +       +P         SS   T ++ D    +G PS  P+Q   S +    S A +
Sbjct: 178 SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARK 237

Query: 241 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC 300
              +P  + +     +TP   GG    + R +  +           ES+ +EE ++SEE 
Sbjct: 238 AAPAPGKVGD-----VTPQVKGGALPPAKRAKKPE----------EESESSEEGSESEEE 282

Query: 301 LWVGVRSPCSPS 312
              G RS    S
Sbjct: 283 APAGTRSQVKAS 294


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
           [Homo sapiens]
          Length = 1450

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 96/400 (24%), Positives = 143/400 (35%), Gaps = 81/400 (20%)

Query: 64  SRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKVDPS 123
           S SS + S SEE+A    RS +K S      K+  +   S   K     T  K      +
Sbjct: 270 SESSEEGSESEEEAPAGTRSQVKAS-----EKILQVRAASAPAKG----TPGKG-----A 315

Query: 124 EPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPA-KVPVPRGADQVV 182
            P+P  +A  V  + +          PE  S  +S + S  +++ PA K  +   A    
Sbjct: 316 TPAPPGKAGAVASQTKAGK-------PEEDSESSSEESSDSEEETPAAKALLQAKASGKT 368

Query: 183 QQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHP------ALS 236
            Q G       + P   R+   P+    T  A  +A+ G     SQS          A +
Sbjct: 369 SQVGAASAPAKESP---RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA 425

Query: 237 QAFQGKNSPQVL--------SEFSGPPLTPTTVGGPRKASFRF--RDEDFYSILSLNSRR 286
           QA     +PQV         S   G    P    GP  A  +   ++ED     S +S  
Sbjct: 426 QAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEED-----SRSSSE 480

Query: 287 ESDDTEEETQSEECLWVGVRSPCSPSHHKRSRFG----------------GTSTPQAKNK 330
           ESD   E   +     V      SP     S  G                G +TP A+  
Sbjct: 481 ESDSDREALAAMNAAQVKPLGK-SPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 539

Query: 331 NFEENAENCRGHSSRRSEPSHGSLRISNAMEPATERPSAGQRLSQDP------GLPDR-- 382
            +EE++E+    SS  S+       +  A+ PA E+ S G  L   P      G P +  
Sbjct: 540 KWEEDSESSSEESSDSSDG-----EVPTAVAPAQEK-SLGNILQAKPTSSPAKGPPQKAG 593

Query: 383 ----ESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAE 418
               +   EK    SE++++S  S D++  P       A+
Sbjct: 594 PVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAK 633



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 59/252 (23%), Positives = 91/252 (36%), Gaps = 45/252 (17%)

Query: 66  SSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKVDPSEP 125
           S+S+ S  EE+A  E   +    A    S L A   +S+K+K K+     KA K   S P
Sbjct: 83  STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKA--ETEKAGKTGNSMP 140

Query: 126 SPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQVVQQE 185
            PA    +  L   K             SPR S + S                 +  ++ 
Sbjct: 141 HPATGKTVANLLSGK-------------SPRKSAEPSANTTL----------VSETEEEG 177

Query: 186 GLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAK-KGDPSA-PSQ---SELHPALSQAFQ 240
            +       +P         SS   T ++ D    +G PS  P+Q   S +    S A +
Sbjct: 178 SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARK 237

Query: 241 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC 300
              +P  + +     +TP   GG    + R +  +           ES+ +EE ++SEE 
Sbjct: 238 AAPAPGKVGD-----VTPQVKGGALPPAKRAKKPE----------EESESSEEGSESEEE 282

Query: 301 LWVGVRSPCSPS 312
              G RS    S
Sbjct: 283 APAGTRSQVKAS 294


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
           [Homo sapiens]
          Length = 958

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 96/400 (24%), Positives = 143/400 (35%), Gaps = 81/400 (20%)

Query: 64  SRSSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKVDPS 123
           S SS + S SEE+A    RS +K S      K+  +   S   K     T  K      +
Sbjct: 270 SESSEEGSESEEEAPAGTRSQVKAS-----EKILQVRAASAPAKG----TPGKG-----A 315

Query: 124 EPSPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPA-KVPVPRGADQVV 182
            P+P  +A  V  + +          PE  S  +S + S  +++ PA K  +   A    
Sbjct: 316 TPAPPGKAGAVASQTKAGK-------PEEDSESSSEESSDSEEETPAAKALLQAKASGKT 368

Query: 183 QQEGLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAKKGDPSAPSQSELHP------ALS 236
            Q G       + P   R+   P+    T  A  +A+ G     SQS          A +
Sbjct: 369 SQVGAASAPAKESP---RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA 425

Query: 237 QAFQGKNSPQVL--------SEFSGPPLTPTTVGGPRKASFRF--RDEDFYSILSLNSRR 286
           QA     +PQV         S   G    P    GP  A  +   ++ED     S +S  
Sbjct: 426 QAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEED-----SRSSSE 480

Query: 287 ESDDTEEETQSEECLWVGVRSPCSPSHHKRSRFG----------------GTSTPQAKNK 330
           ESD   E   +     V      SP     S  G                G +TP A+  
Sbjct: 481 ESDSDREALAAMNAAQVKPLGK-SPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 539

Query: 331 NFEENAENCRGHSSRRSEPSHGSLRISNAMEPATERPSAGQRLSQDP------GLPDR-- 382
            +EE++E+    SS  S+       +  A+ PA E+ S G  L   P      G P +  
Sbjct: 540 KWEEDSESSSEESSDSSDG-----EVPTAVAPAQEK-SLGNILQAKPTSSPAKGPPQKAG 593

Query: 383 ----ESATEKDRGGSENAKKSPLSWDTKSEPRQEVGVNAE 418
               +   EK    SE++++S  S D++  P       A+
Sbjct: 594 PVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAK 633



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 59/252 (23%), Positives = 91/252 (36%), Gaps = 45/252 (17%)

Query: 66  SSSKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKVDPSEP 125
           S+S+ S  EE+A  E   +    A    S L A   +S+K+K K+     KA K   S P
Sbjct: 83  STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKA--ETEKAGKTGNSMP 140

Query: 126 SPADQAPMVLLRKRKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGADQVVQQE 185
            PA    +  L   K             SPR S + S                 +  ++ 
Sbjct: 141 HPATGKTVANLLSGK-------------SPRKSAEPSANTTL----------VSETEEEG 177

Query: 186 GLMCNTKLKRPNQERRNLVPSSQPMTENAPDRAK-KGDPSA-PSQ---SELHPALSQAFQ 240
            +       +P         SS   T ++ D    +G PS  P+Q   S +    S A +
Sbjct: 178 SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARK 237

Query: 241 GKNSPQVLSEFSGPPLTPTTVGGPRKASFRFRDEDFYSILSLNSRRESDDTEEETQSEEC 300
              +P  + +     +TP   GG    + R +  +           ES+ +EE ++SEE 
Sbjct: 238 AAPAPGKVGD-----VTPQVKGGALPPAKRAKKPE----------EESESSEEGSESEEE 282

Query: 301 LWVGVRSPCSPS 312
              G RS    S
Sbjct: 283 APAGTRSQVKAS 294


>gi|40255016 membrane-associated RING-CH protein IX [Homo sapiens]
          Length = 346

 Score = 39.3 bits (90), Expect = 0.015
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 10/56 (17%)

Query: 659 CRICQIAGGSPSNPLLEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMC 714
           CRIC    G     LL PC C GS++  HQ CL +W+  +           +CE+C
Sbjct: 110 CRIC--FQGPEQGELLSPCRCDGSVRCTHQPCLIRWISER--------GSWSCELC 155


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 39.3 bits (90), Expect = 0.015
 Identities = 59/279 (21%), Positives = 102/279 (36%), Gaps = 46/279 (16%)

Query: 22  QHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERS--RFSSRSSSKQSSSEEDALT 79
           Q +++ E  A +++Q+  +D  +K+  +   ++    RS  R  SRS S +  S      
Sbjct: 133 QRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRE 192

Query: 80  EPRSSIKISAFKCDS-----------KLPAIDQTSVKQKHKST---------MTVRKAEK 119
             RS  +    +  S           K P + + SVK K  S          + V K E 
Sbjct: 193 RKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEP 252

Query: 120 V-DPSEPSPADQAPMVLLRKR---------KPNLRRFTVSPESHSPRASGDRSRQKQQWP 169
           + +P EPSP   +     +++         K   R  + SP    PR    RSR +   P
Sbjct: 253 IPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRR-HRSRSRSYSP 311

Query: 170 AKVPVPRGADQVVQQEGLMCNTKLKRPNQERRNLVPS----------SQPMTENAPDRAK 219
            + P PR      ++       ++  P + RR+  P           S   + ++  R++
Sbjct: 312 RRRPSPRRRPSPRRRTP---PRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSR 368

Query: 220 KGDPSAPSQSELHPALSQAFQGKNSPQVLSEFSGPPLTP 258
                 P ++   P  ++      SP        PP TP
Sbjct: 369 SPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATP 407



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 41/210 (19%), Positives = 80/210 (38%), Gaps = 13/210 (6%)

Query: 22  QHKVDSEYQACLRRQEYRRDPNEKKRD--QFWGQETSFERSRFSSRSSSKQSSSEEDALT 79
           +H+  S   +  RR   RR P+ ++R   +         RSR   R   + S+S   + +
Sbjct: 301 RHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSS 360

Query: 80  EPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKVDP-SEPSPADQAPMVLLRK 138
              SS   S  K   K  +      ++   S    R+  +  P + P P  +      + 
Sbjct: 361 SSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQS 420

Query: 139 RKPNLRRFTVSPESHSPRASGDRSRQKQQWPAKVPVPRGAD----------QVVQQEGLM 188
            +    R +VSP   S + +  +  +K++ P+  P PR  +          ++   + + 
Sbjct: 421 NRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQ 480

Query: 189 CNTKLKRPNQERRNLVPSSQPMTENAPDRA 218
              + +R NQ+  +   SS    +  P R+
Sbjct: 481 QRRQYRRQNQQSSSDSGSSSSSEDERPKRS 510



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 79/377 (20%), Positives = 132/377 (35%), Gaps = 67/377 (17%)

Query: 68  SKQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKVDPSEPSP 127
           ++ S + + +    +S + +S  +   K+     T  ++        RK E  +  E   
Sbjct: 411 TRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKG 470

Query: 128 ADQAPMVLLRKRKPNLRR---------FTVSPESHSPRAS----GDRSRQKQQWPAKV-- 172
              A    +++R+   R+          + S E   P+ S    G+  R+++  P++   
Sbjct: 471 GKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSAS 530

Query: 173 PVPRGADQVVQQEGLMCNTKLKRPNQERRNLVPSSQP---MTENAPDRAKKGDP----SA 225
           P PR   +     G    +    P + RR+  P+  P    T   P R +   P     +
Sbjct: 531 PSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRS 590

Query: 226 PSQSELHPALSQAFQGKNSPQVLSEFSGPPLTPTTVGGP-----RKASFRFRDEDFYSIL 280
           PS     P + + +    SP      + PP  P     P     R+ S     +   S +
Sbjct: 591 PSPRRYSPPIQRRY--SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPV 648

Query: 281 ------SLNSRRESDDTEEETQSEECLWVGVRSP-----CSPSHHKRSRFGGTSTPQAKN 329
                 SL+S+     +   +  E       RSP      SPS   R+    +S P  + 
Sbjct: 649 TKRRSPSLSSKHRKGSSPSRSTRE------ARSPQPNKRHSPSPRPRAPQTSSSPPPVR- 701

Query: 330 KNFEENAENCRGHSS---RRSEPSHGS---LRISNAMEPATERPSAGQRLSQDPGLPDRE 383
                     RG SS   RR  PS  +    R+S   EP   + +A    S  P    R 
Sbjct: 702 ----------RGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAA----SPSPQSVRRV 747

Query: 384 SATEKDRGGSENAKKSP 400
           S++    G  E A K P
Sbjct: 748 SSSRSVSGSPEPAAKKP 764


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 38.5 bits (88), Expect = 0.025
 Identities = 20/116 (17%), Positives = 48/116 (41%)

Query: 9   QKFFSDVQYLRDMQHKVDSEYQACLRRQEYRRDPNEKKRDQFWGQETSFERSRFSSRSSS 68
           +K +   + +R+   K+  + +   R++E  R+  EK++++ W QE          R   
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426

Query: 69  KQSSSEEDALTEPRSSIKISAFKCDSKLPAIDQTSVKQKHKSTMTVRKAEKVDPSE 124
           ++   +E+ + E    ++    K       + +   K + +     R+ EK+   E
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQE 482


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.126    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,690,380
Number of Sequences: 37866
Number of extensions: 1779861
Number of successful extensions: 7202
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 200
Number of HSP's that attempted gapping in prelim test: 6773
Number of HSP's gapped (non-prelim): 590
length of query: 808
length of database: 18,247,518
effective HSP length: 110
effective length of query: 698
effective length of database: 14,082,258
effective search space: 9829416084
effective search space used: 9829416084
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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