Search of human proteins with 15431316

Search of human proteins with 15431316

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
         (600 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                   1191   0.0  
gi|4504935 keratin 85 [Homo sapiens]                                  579   e-165
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   546   e-155
gi|27477127 keratin 82 [Homo sapiens]                                 545   e-155
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   544   e-155
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   544   e-155
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   544   e-155
gi|14318422 keratin 86 [Homo sapiens]                                 544   e-155
gi|169790841 keratin 83 [Homo sapiens]                                540   e-153
gi|119395754 keratin 5 [Homo sapiens]                                 539   e-153
gi|5031839 keratin 6A [Homo sapiens]                                  525   e-149
gi|155969697 keratin 6C [Homo sapiens]                                520   e-147
gi|119703753 keratin 6B [Homo sapiens]                                519   e-147
gi|153791158 keratin 75 [Homo sapiens]                                509   e-144
gi|153791670 keratin 76 [Homo sapiens]                                482   e-136
gi|119395750 keratin 1 [Homo sapiens]                                 472   e-133
gi|109148552 keratin 3 [Homo sapiens]                                 468   e-132
gi|67782365 keratin 7 [Homo sapiens]                                  468   e-132
gi|32567786 keratin 6L [Homo sapiens]                                 458   e-129
gi|4504919 keratin 8 [Homo sapiens]                                   457   e-128
gi|109255249 keratin 4 [Homo sapiens]                                 451   e-127
gi|47132620 keratin 2 [Homo sapiens]                                  444   e-124
gi|15618995 keratin 71 [Homo sapiens]                                 440   e-123
gi|28173564 keratin 73 [Homo sapiens]                                 439   e-123
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       431   e-121
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      431   e-121
gi|148612803 keratin 6 irs4 [Homo sapiens]                            427   e-119
gi|194018511 keratin 77 [Homo sapiens]                                425   e-119
gi|89357932 keratin 5b [Homo sapiens]                                 371   e-103
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      343   3e-94

>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score = 1191 bits (3080), Expect = 0.0
 Identities = 600/600 (100%), Positives = 600/600 (100%)

Query: 1   MSCRSYRVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFGS 60
           MSCRSYRVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFGS
Sbjct: 1   MSCRSYRVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFGS 60

Query: 61  YSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGP 120
           YSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGP
Sbjct: 61  YSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGP 120

Query: 121 GFGYRVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFI 180
           GFGYRVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFI
Sbjct: 121 GFGYRVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFI 180

Query: 181 DKVRFLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERN 240
           DKVRFLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERN
Sbjct: 181 DKVRFLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERN 240

Query: 241 HLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKT 300
           HLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKT
Sbjct: 241 HLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKT 300

Query: 301 LYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKY 360
           LYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKY
Sbjct: 301 LYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKY 360

Query: 361 EEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATL 420
           EEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATL
Sbjct: 361 EEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATL 420

Query: 421 SDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGV 480
           SDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGV
Sbjct: 421 SDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGV 480

Query: 481 GPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSLGGARVA 540
           GPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSLGGARVA
Sbjct: 481 GPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSLGGARVA 540

Query: 541 PATGDLLSTGTRSGSMLISEACVPSVPCPLPTQGGFSSCSGGRSSSVRFVSTTTSCRTKY 600
           PATGDLLSTGTRSGSMLISEACVPSVPCPLPTQGGFSSCSGGRSSSVRFVSTTTSCRTKY
Sbjct: 541 PATGDLLSTGTRSGSMLISEACVPSVPCPLPTQGGFSSCSGGRSSSVRFVSTTTSCRTKY 600


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  579 bits (1492), Expect = e-165
 Identities = 321/535 (60%), Positives = 378/535 (70%), Gaps = 50/535 (9%)

Query: 1   MSCRSYRVSSGHRVG-NFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFG 59
           MSCRSYR+SSG  V  NFSSCSA+ P+  NR   ++        +RGL  FGSRS+   G
Sbjct: 1   MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLG 60

Query: 60  SYSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGG 119
           S  PRIA  G R                           A SC                G
Sbjct: 61  SCGPRIAVGGFR---------------------------AGSC----------------G 77

Query: 120 PGFGYRVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASF 179
             FGYR GGV  P+ P IT V+VN+SLLTPLNLEIDPNAQ VK++EKEQIK+LN++FA+F
Sbjct: 78  RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 137

Query: 180 IDKVRFLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAER 239
           IDKVRFLEQQNKLLETKW F Q Q+C  SNLEPLF  YI  LRR+ E + +D  RL +E 
Sbjct: 138 IDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETLRREAECVEADSGRLASEL 197

Query: 240 NHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLK 299
           NH+Q+VLEG+KKKYEEEV  RA AENEFV LKKDVD A++ KSDLEANV+ L +E  FL+
Sbjct: 198 NHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLR 257

Query: 300 TLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTK 359
            LY EEI++LQ+HIS+TSVIVKMDNSRDLN+D IIAE+KAQY++VA RSRA+AE+WY++K
Sbjct: 258 RLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSK 317

Query: 360 YEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEAT 419
            EEM+ T  +H + LR  + EINEL R+IQRL AEIE+AK QRAKLEAAVAEAEQQGEA 
Sbjct: 318 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAA 377

Query: 420 LSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEG 479
           LSDA+CKLA+LE ALQ+AKQDMA  L EYQE+MN+KLGLDIEIATYRRLLEGEE RLCEG
Sbjct: 378 LSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCEG 437

Query: 480 VGPVNISVSSSRGGLVCG--PEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGP 532
           VG VN+ VSSSRGG+ CG        G  ++ G     GS +V A      SC P
Sbjct: 438 VGSVNVCVSSSRGGVSCGGLSYSTTPGRQITSGPSAIGGSITVVAPD----SCAP 488


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  546 bits (1406), Expect = e-155
 Identities = 300/497 (60%), Positives = 367/497 (73%), Gaps = 28/497 (5%)

Query: 83  CGMGFGDGRGVGL----GPRADSCV-------------GL--GFGAGS---GIGYGFGGP 120
           CG GFG GR        GPR   C              GL  GFG+ S   G   G  G 
Sbjct: 3   CGSGFG-GRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGR 61

Query: 121 GFGYRVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFI 180
            FGYR GGV  P+ P IT V+VN+SLLTPLNLEIDPNAQ VK++EKEQIK+LN++FA+FI
Sbjct: 62  SFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFI 121

Query: 181 DKVRFLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERN 240
           DKVRFLEQQNKLLETK  F Q ++C +SNLEPLFE YI  LRR+ E + +D  RL +E N
Sbjct: 122 DKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELN 181

Query: 241 HLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKT 300
           H+Q+VLEG+KKKYEEEV  RA AENEFVALKKDVD A++ KSDLEANV+ L QEIDFL+ 
Sbjct: 182 HVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRR 241

Query: 301 LYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKY 360
           LY EEI +LQSHIS+TSV+VK+DNSRDLN+D IIAE+KAQY+++  RSRA+AE+WY++K 
Sbjct: 242 LYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKC 301

Query: 361 EEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATL 420
           EEM+ T  +H + LR  + EINEL R+IQRL AE+E+AK Q +KLEAAVA++EQQGEA L
Sbjct: 302 EEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAAL 361

Query: 421 SDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGV 480
           SDA+CKLA+LE ALQ+AKQDMA  + EYQE+MN+KLGLDIEIATYRRLLEGEE RLCEG+
Sbjct: 362 SDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGI 421

Query: 481 GPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSG-SSSVCATSGVLASCG---PSLGG 536
           G VN+ VSSSRGG+VCG +  V+GS    G V  +  + +V  ++G+ A CG    + GG
Sbjct: 422 GAVNVCVSSSRGGVVCG-DLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLNTTCGG 480

Query: 537 ARVAPATGDLLSTGTRS 553
                 +  + S G  S
Sbjct: 481 GSCGVGSCGISSLGVGS 497


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  545 bits (1404), Expect = e-155
 Identities = 308/552 (55%), Positives = 377/552 (68%), Gaps = 60/552 (10%)

Query: 1   MSCRSYRVSSGHRVGNFSSCSAMTPQNLNRFRANSVSC--WSGPGFRGLGSFGSRSVITF 58
           MS  S++  S     +FSS SA+ P+ +  +  +   C    G G R LG  GSRS+   
Sbjct: 1   MSYHSFQPGSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSL--- 57

Query: 59  GSYSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFG 118
                                   C +GFG  R       A  C G              
Sbjct: 58  ------------------------CNVGFGRPRV------ASRCGGTL------------ 75

Query: 119 GPGFGYRVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFAS 178
            PGFGYR+G    P+A  IT VT+N+SLL PL LEIDP  QRVK+DEKEQIK LNN+FAS
Sbjct: 76  -PGFGYRLGATCGPSA-CITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFAS 133

Query: 179 FIDKVRFLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAE 238
           FI+KVRFLEQ+NKLLETKW+F+Q+Q+C ++N+EP+FE YI+ LRRQL+ +  D+ RL++E
Sbjct: 134 FINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCVSGDRVRLESE 193

Query: 239 RNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFL 298
              LQ  LEG+KKKYEEE+  R   ENEFVALKKDVD AF+ K+DLE N + L QEIDFL
Sbjct: 194 LCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEALVQEIDFL 253

Query: 299 KTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQT 358
           K+LY EEI LLQS ISETSVIVKMDNSR+L++DGIIAE+KAQY+++A RS+A+AEAWYQ 
Sbjct: 254 KSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQC 313

Query: 359 KYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEA 418
           +YEE++VTAG HCDNLRN +NEI E+ +LIQRL+ E E+ KAQR KLE A+AEAEQQGEA
Sbjct: 314 RYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEA 373

Query: 419 TLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCE 478
            L+DAKCKLA LE ALQ+AKQDMA  L EYQE+MN+KLGLDIEIATYRRLLEGEE RLCE
Sbjct: 374 ALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCE 433

Query: 479 GVGPVNISVSSSRGGLV---CGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGP--- 532
           G+GPVNISVSSS+G  +   CG    V+   LS G +  +G  S+  T  +   C P   
Sbjct: 434 GIGPVNISVSSSKGAFLYEPCG----VSTPVLSTGVLRSNGGCSIVGTGELYVPCEPQGL 489

Query: 533 -SLGGARVAPAT 543
            S G  R +  T
Sbjct: 490 LSCGSGRKSSMT 501


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  544 bits (1402), Expect = e-155
 Identities = 295/477 (61%), Positives = 362/477 (75%), Gaps = 17/477 (3%)

Query: 65  IAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGY 124
           I+A G RP  C +   A    G    RG+  G  + S  G GF AGS       G  FGY
Sbjct: 15  ISACGPRPGRCCIT--AAPYRGISCYRGLTGGFGSHSVCG-GFRAGSC------GRSFGY 65

Query: 125 RVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVR 184
           R GGV  P+ P IT V+VN+SLLTPLNLEIDPNAQ VK++EKEQIK+LN++FA+FIDKVR
Sbjct: 66  RSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVR 125

Query: 185 FLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQD 244
           FLEQQNKLLETK  F Q ++C +SNLEPLFE YI  LRR+ E + +D  RL +E NH+Q+
Sbjct: 126 FLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQE 185

Query: 245 VLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYME 304
           VLEG+KKKYEEEV  RA AENEFVALKKDVD A++ KSDLEANV+ L QEIDFL+ LY E
Sbjct: 186 VLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 245

Query: 305 EIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQ 364
           EI++LQSHIS+TSV+VK+DNSRDLN+D IIAE+KAQY+++  RSRA+AE+WY++K EEM+
Sbjct: 246 EIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMK 305

Query: 365 VTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAK 424
            T  +H + LR  + EINEL R+IQRL AE+E+AK Q +KLEAAVA++EQQGEA LSDA+
Sbjct: 306 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 365

Query: 425 CKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVN 484
           CKLA+LE ALQ+AKQDMA  + EYQE+MN+KLGLDIEIATYRRLLEGEE RLCEGVG VN
Sbjct: 366 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGSVN 425

Query: 485 ISVSSSRGGLVCG------PEPLVAG--STLSRGGVTFSGSSSVCATSGVLASCGPS 533
           + VSSSRGG+VCG        P+V+   S++        G+++ CA S  +  CG S
Sbjct: 426 VCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCGGS 482


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  544 bits (1402), Expect = e-155
 Identities = 295/477 (61%), Positives = 362/477 (75%), Gaps = 17/477 (3%)

Query: 65  IAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGY 124
           I+A G RP  C +   A    G    RG+  G  + S  G GF AGS       G  FGY
Sbjct: 15  ISACGPRPGRCCIT--AAPYRGISCYRGLTGGFGSHSVCG-GFRAGSC------GRSFGY 65

Query: 125 RVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVR 184
           R GGV  P+ P IT V+VN+SLLTPLNLEIDPNAQ VK++EKEQIK+LN++FA+FIDKVR
Sbjct: 66  RSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVR 125

Query: 185 FLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQD 244
           FLEQQNKLLETK  F Q ++C +SNLEPLFE YI  LRR+ E + +D  RL +E NH+Q+
Sbjct: 126 FLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQE 185

Query: 245 VLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYME 304
           VLEG+KKKYEEEV  RA AENEFVALKKDVD A++ KSDLEANV+ L QEIDFL+ LY E
Sbjct: 186 VLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 245

Query: 305 EIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQ 364
           EI++LQSHIS+TSV+VK+DNSRDLN+D IIAE+KAQY+++  RSRA+AE+WY++K EEM+
Sbjct: 246 EIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMK 305

Query: 365 VTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAK 424
            T  +H + LR  + EINEL R+IQRL AE+E+AK Q +KLEAAVA++EQQGEA LSDA+
Sbjct: 306 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 365

Query: 425 CKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVN 484
           CKLA+LE ALQ+AKQDMA  + EYQE+MN+KLGLDIEIATYRRLLEGEE RLCEGVG VN
Sbjct: 366 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGSVN 425

Query: 485 ISVSSSRGGLVCG------PEPLVAG--STLSRGGVTFSGSSSVCATSGVLASCGPS 533
           + VSSSRGG+VCG        P+V+   S++        G+++ CA S  +  CG S
Sbjct: 426 VCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCGGS 482


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  544 bits (1402), Expect = e-155
 Identities = 295/477 (61%), Positives = 362/477 (75%), Gaps = 17/477 (3%)

Query: 65  IAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGY 124
           I+A G RP  C +   A    G    RG+  G  + S  G GF AGS       G  FGY
Sbjct: 15  ISACGPRPGRCCIT--AAPYRGISCYRGLTGGFGSHSVCG-GFRAGSC------GRSFGY 65

Query: 125 RVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVR 184
           R GGV  P+ P IT V+VN+SLLTPLNLEIDPNAQ VK++EKEQIK+LN++FA+FIDKVR
Sbjct: 66  RSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVR 125

Query: 185 FLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQD 244
           FLEQQNKLLETK  F Q ++C +SNLEPLFE YI  LRR+ E + +D  RL +E NH+Q+
Sbjct: 126 FLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQE 185

Query: 245 VLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYME 304
           VLEG+KKKYEEEV  RA AENEFVALKKDVD A++ KSDLEANV+ L QEIDFL+ LY E
Sbjct: 186 VLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 245

Query: 305 EIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQ 364
           EI++LQSHIS+TSV+VK+DNSRDLN+D IIAE+KAQY+++  RSRA+AE+WY++K EEM+
Sbjct: 246 EIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMK 305

Query: 365 VTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAK 424
            T  +H + LR  + EINEL R+IQRL AE+E+AK Q +KLEAAVA++EQQGEA LSDA+
Sbjct: 306 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 365

Query: 425 CKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVN 484
           CKLA+LE ALQ+AKQDMA  + EYQE+MN+KLGLDIEIATYRRLLEGEE RLCEGVG VN
Sbjct: 366 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGSVN 425

Query: 485 ISVSSSRGGLVCG------PEPLVAG--STLSRGGVTFSGSSSVCATSGVLASCGPS 533
           + VSSSRGG+VCG        P+V+   S++        G+++ CA S  +  CG S
Sbjct: 426 VCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCGGS 482


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  544 bits (1402), Expect = e-155
 Identities = 295/477 (61%), Positives = 362/477 (75%), Gaps = 17/477 (3%)

Query: 65  IAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGY 124
           I+A G RP  C +   A    G    RG+  G  + S  G GF AGS       G  FGY
Sbjct: 15  ISACGPRPGRCCIT--AAPYRGISCYRGLTGGFGSHSVCG-GFRAGSC------GRSFGY 65

Query: 125 RVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVR 184
           R GGV  P+ P IT V+VN+SLLTPLNLEIDPNAQ VK++EKEQIK+LN++FA+FIDKVR
Sbjct: 66  RSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVR 125

Query: 185 FLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQD 244
           FLEQQNKLLETK  F Q ++C +SNLEPLFE YI  LRR+ E + +D  RL +E NH+Q+
Sbjct: 126 FLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQE 185

Query: 245 VLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYME 304
           VLEG+KKKYEEEV  RA AENEFVALKKDVD A++ KSDLEANV+ L QEIDFL+ LY E
Sbjct: 186 VLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 245

Query: 305 EIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQ 364
           EI++LQSHIS+TSV+VK+DNSRDLN+D IIAE+KAQY+++  RSRA+AE+WY++K EEM+
Sbjct: 246 EIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMK 305

Query: 365 VTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAK 424
            T  +H + LR  + EINEL R+IQRL AE+E+AK Q +KLEAAVA++EQQGEA LSDA+
Sbjct: 306 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 365

Query: 425 CKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVN 484
           CKLA+LE ALQ+AKQDMA  + EYQE+MN+KLGLDIEIATYRRLLEGEE RLCEGVG VN
Sbjct: 366 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGSVN 425

Query: 485 ISVSSSRGGLVCG------PEPLVAG--STLSRGGVTFSGSSSVCATSGVLASCGPS 533
           + VSSSRGG+VCG        P+V+   S++        G+++ CA S  +  CG S
Sbjct: 426 VCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCGGS 482


>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  540 bits (1391), Expect = e-153
 Identities = 290/468 (61%), Positives = 360/468 (76%), Gaps = 11/468 (2%)

Query: 65  IAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGY 124
           ++A G RP  C +   A    G    RG+  G  + S  G GF AGS       G  FGY
Sbjct: 20  VSACGPRPSRCCIT--AAPYRGISCYRGLTGGFGSHSVCG-GFRAGSC------GRSFGY 70

Query: 125 RVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVR 184
           R GGV  P+ P IT V+VN+SLLTPLNLEIDPNAQ VK++EKEQIK+LN++FA+FIDKVR
Sbjct: 71  RSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVR 130

Query: 185 FLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQD 244
           FLEQQNKLLETK  F Q ++C +SNLEPLF  YI  LRR+ E + +D  RL +E NH+Q+
Sbjct: 131 FLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQE 190

Query: 245 VLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYME 304
           VLEG+KKKYEEEV  RA AENEFVALKKDVD A++ KSDLEANV+ L QEIDFL+ LY E
Sbjct: 191 VLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 250

Query: 305 EIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQ 364
           EI++LQSHIS+TSV+VK+DNSRDLN+D I+AE+KAQY+++A RSRA+AE+WY++K EEM+
Sbjct: 251 EIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMK 310

Query: 365 VTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAK 424
            T  +H + LR  + EINEL R+IQRL AE+E+AK Q +KLEAAVA++EQQGEA LSDA+
Sbjct: 311 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 370

Query: 425 CKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVN 484
           CKLA+LE ALQ+AKQDMA  + EYQE+MN+KLGLDIEIATYRRLLEGEE RLCEGV  VN
Sbjct: 371 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVEAVN 430

Query: 485 ISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSG-SSSVCATSGVLASCG 531
           + VSSSRGG+VCG +  V+GS    G V  +  + ++  ++G+   CG
Sbjct: 431 VCVSSSRGGVVCG-DLCVSGSRPVTGSVCSAPCNGNLVVSTGLCKPCG 477


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  539 bits (1389), Expect = e-153
 Identities = 325/619 (52%), Positives = 407/619 (65%), Gaps = 68/619 (10%)

Query: 9   SSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSG-----------PGFRGLGSFGSRSVIT 57
           S G R  +FS+ SA+TP +++R    SVS   G            G  G+G +GSRS+  
Sbjct: 11  SGGSR--SFSTASAITP-SVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRSLYN 67

Query: 58  FGSYSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGF 117
            G  S RI+   S       RFGAG G G+G G G G G       G G GAG G G G 
Sbjct: 68  LGG-SKRISISTSGGSFRN-RFGAGAGGGYGFGGGAGSG------FGFGGGAGGGFGLG- 118

Query: 118 GGPGFGYRVGGVGVPAAP--SITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNK 175
           GG GFG   GG G P  P   I  VTVN+SLLTPLNL+IDP+ QRV+ +E+EQIKTLNNK
Sbjct: 119 GGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNK 178

Query: 176 FASFIDKVRFLEQQNKLLETKWSFLQEQ--KCIRSNLEPLFESYITNLRRQLEVLVSDQA 233
           FASFIDKVRFLEQQNK+L+TKW+ LQEQ  K +R NLEPLFE YI NLRRQL+ +V ++ 
Sbjct: 179 FASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERG 238

Query: 234 RLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQ 293
           RL +E  ++QD++E FK KYE+E+  R  AENEFV LKKDVDAA+MNK +LEA VD L  
Sbjct: 239 RLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMD 298

Query: 294 EIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAE 353
           EI+F+K  +  E+  +Q+H+S+TSV++ MDN+R+L+LD IIAEVKAQYEE+A RSR +AE
Sbjct: 299 EINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAE 358

Query: 354 AWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAE 413
           +WYQTKYEE+Q TAG+H D+LRN ++EI+E+ R+IQRL+AEI++ K Q A L+ A+A+AE
Sbjct: 359 SWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAE 418

Query: 414 QQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEE 473
           Q+GE  L DA+ KLA+LE ALQ+AKQDMAR L EYQELMN KL LD+EIATYR+LLEGEE
Sbjct: 419 QRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEE 478

Query: 474 SRLC-EGVGPVNISV-----------SSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVC 521
            RL  EGVGPVNISV            S  GG + G      G  L+ G    SGS    
Sbjct: 479 CRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGS---SGSYYSS 535

Query: 522 ATSGVLASCGPSLGGARVAPATGDLLSTGTRSGSMLISEACVPSVPCPLPTQGGFSSCSG 581
           ++ GV    G S+GG+  + ++G  L  G  SG                          G
Sbjct: 536 SSGGVGLGGGLSVGGSGFSASSGRGLGVGFGSG--------------------------G 569

Query: 582 GRSSSVRFVSTTTSCRTKY 600
           G SSSV+FVSTT+S R  +
Sbjct: 570 GSSSSVKFVSTTSSSRKSF 588


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  525 bits (1351), Expect = e-149
 Identities = 313/605 (51%), Positives = 388/605 (64%), Gaps = 62/605 (10%)

Query: 7   RVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGS------FGSRSVITFGS 60
           R  S  R G FS+ SA  P  ++R   +SVS     G  GLG       FGSRS+   G 
Sbjct: 9   RSHSSSRRG-FSANSARLP-GVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGG 66

Query: 61  YSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGP 120
                   GS  I  G    AG   GFG G G G G    + +G G G G+G+  GFGGP
Sbjct: 67  SKRISIGGGSCAISGGYGSRAGGSYGFG-GAGSGFGFGGGAGIGFGLGGGAGLAGGFGGP 125

Query: 121 GFGYRVGGVGVPAAP--SITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFAS 178
           GF         P  P   I  VTVN+SLLTPLNL+IDP  QRV+ +E+EQIKTLNNKFAS
Sbjct: 126 GF---------PVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFAS 176

Query: 179 FIDKVRFLEQQNKLLETKWSFLQEQ--KCIRSNLEPLFESYITNLRRQLEVLVSDQARLQ 236
           FIDKVRFLEQQNK+LETKW+ LQEQ  K +R NLEPLFE YI NLRRQL+ +V ++ RL 
Sbjct: 177 FIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 236

Query: 237 AERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEID 296
           +E   +QD++E FK KYE+E+  R  AENEFV LKKDVDAA+MNK +L+A  DTLT EI+
Sbjct: 237 SELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEIN 296

Query: 297 FLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWY 356
           FL+ LY  E+  +Q+HIS+TSV++ MDN+R+L+LD IIAEVKAQYEE+A+RSRA+AE+WY
Sbjct: 297 FLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWY 356

Query: 357 QTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQG 416
           QTKYEE+QVTAG+H D+LRN + EI E+ R+IQRL++EI+H K Q A L+AA+A+AEQ+G
Sbjct: 357 QTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRG 416

Query: 417 EATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRL 476
           E  L DAK KL  LE ALQ+AKQD+AR L EYQELMN KL LD+EIATYR+LLEGEE RL
Sbjct: 417 EMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRL 476

Query: 477 -CEGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSLG 535
             EGVG VNISV  S      G    V       GG ++S  S +    G  +S G ++G
Sbjct: 477 NGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIG 536

Query: 536 GARVAPATGDLLSTGTRSGSMLISEACVPSVPCPLPTQGGFSSCSGGRSSSVRFVSTTTS 595
                                                 GG SS  GG SS++++ +T++S
Sbjct: 537 --------------------------------------GGLSSVGGG-SSTIKYTTTSSS 557

Query: 596 CRTKY 600
            R  Y
Sbjct: 558 SRKSY 562


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  520 bits (1339), Expect = e-147
 Identities = 309/605 (51%), Positives = 388/605 (64%), Gaps = 62/605 (10%)

Query: 7   RVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGS------FGSRSVITFGS 60
           R  S  R G FS+ SA  P  ++R   +S+S     G  GLG       FGSRS+   G 
Sbjct: 9   RSHSSSRRG-FSANSARLP-GVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGG 66

Query: 61  YSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGP 120
                   GS  I  G    AG   GFG G G G G    + +G G G G+G+  GFGGP
Sbjct: 67  SKRISIGGGSCAISGGYGSRAGGSYGFG-GAGSGFGFGGGAGIGFGLGGGAGLAGGFGGP 125

Query: 121 GFGYRVGGVGVPAAP--SITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFAS 178
           GF         P  P   I  VTVN+SLLTPLNL+IDP  QRV+ +E+EQIKTLNNKFAS
Sbjct: 126 GF---------PVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFAS 176

Query: 179 FIDKVRFLEQQNKLLETKWSFLQEQ--KCIRSNLEPLFESYITNLRRQLEVLVSDQARLQ 236
           FIDKVRFLEQQNK+L+TKW+ LQEQ  K +R NLEPLFE YI NLRRQL+ +V ++ RL 
Sbjct: 177 FIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 236

Query: 237 AERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEID 296
           +E  ++QD++E  K KYE+E+  R  AENEFV LKKDVDAA+MNK +L+A  DTLT EI+
Sbjct: 237 SELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEIN 296

Query: 297 FLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWY 356
           FL+ LY  E+  +Q+HIS+TSV++ MDN+R+L+LD IIAEVKAQYEE+A+RSRA+AE+WY
Sbjct: 297 FLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWY 356

Query: 357 QTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQG 416
           QTKYEE+QVTAG+H D+LRN + EI E+ R+IQRL++EI+H K Q A L+AA+A+AEQ+G
Sbjct: 357 QTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRG 416

Query: 417 EATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRL 476
           E  L DAK KL  LE ALQ+AKQD+AR L EYQELMN KL LD+EIATYR+LLEGEE RL
Sbjct: 417 EMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRL 476

Query: 477 -CEGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSLG 535
             EGVG VN+SV  S      G    V       GG ++S  S +    G  +S G ++G
Sbjct: 477 NGEGVGQVNVSVVQSTISSGYGGASGVGSGLGLGGGSSYSYGSGLGIGGGFSSSSGRAIG 536

Query: 536 GARVAPATGDLLSTGTRSGSMLISEACVPSVPCPLPTQGGFSSCSGGRSSSVRFVSTTTS 595
                                                 GG SS  GG SS++++ +T++S
Sbjct: 537 --------------------------------------GGLSSVGGG-SSTIKYTTTSSS 557

Query: 596 CRTKY 600
            R  Y
Sbjct: 558 SRKSY 562


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  519 bits (1337), Expect = e-147
 Identities = 309/605 (51%), Positives = 387/605 (63%), Gaps = 62/605 (10%)

Query: 7   RVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGS------FGSRSVITFGS 60
           R  S  R G FS+ SA  P  ++R   +S+S     G  GLG       FGSRS+   G 
Sbjct: 9   RSHSSSRRG-FSANSARLP-GVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGG 66

Query: 61  YSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGP 120
                   GS  I  G    AG   GFG G G G G    + +G G G G+G+  GFGGP
Sbjct: 67  SKRISIGGGSCAISGGYGSRAGGSYGFG-GAGSGFGFGGGAGIGFGLGGGAGLAGGFGGP 125

Query: 121 GFGYRVGGVGVPAAP--SITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFAS 178
           GF         P  P   I  VTVN+SLLTPLNL+IDP  QRV+ +E+EQIKTLNNKFAS
Sbjct: 126 GF---------PVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFAS 176

Query: 179 FIDKVRFLEQQNKLLETKWSFLQEQ--KCIRSNLEPLFESYITNLRRQLEVLVSDQARLQ 236
           FIDKVRFLEQQNK+L+TKW+ LQEQ  K +R NLEPLFE YI NLRRQL+ +V ++ RL 
Sbjct: 177 FIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLD 236

Query: 237 AERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEID 296
           +E  ++QD++E  K KYE+E+  R  AENEFV LKKDVDAA+MNK +L+A  DTLT EI+
Sbjct: 237 SELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEIN 296

Query: 297 FLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWY 356
           FL+ LY  E+  +Q+HIS+TSV++ MDN+R+L+LD IIAEVKAQYEE+A+RSRA+AE+WY
Sbjct: 297 FLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWY 356

Query: 357 QTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQG 416
           QTKYEE+Q+TAG+H D+LRN + EI E+ R+IQRL++EI+H K Q A L+AA+A+AEQ+G
Sbjct: 357 QTKYEELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRG 416

Query: 417 EATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRL 476
           E  L DAK KL  LE ALQ+AKQD+AR L EYQELMN KL LD+EIATYR+LLEGEE RL
Sbjct: 417 EMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRL 476

Query: 477 -CEGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSLG 535
             EGVG VNISV  S      G    V       GG ++S  S +    G  +S G + G
Sbjct: 477 NGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRATG 536

Query: 536 GARVAPATGDLLSTGTRSGSMLISEACVPSVPCPLPTQGGFSSCSGGRSSSVRFVSTTTS 595
                                                 GG SS  GG SS++++ +T++S
Sbjct: 537 --------------------------------------GGLSSVGGG-SSTIKYTTTSSS 557

Query: 596 CRTKY 600
            R  Y
Sbjct: 558 SRKSY 562


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  509 bits (1310), Expect = e-144
 Identities = 309/613 (50%), Positives = 392/613 (63%), Gaps = 86/613 (14%)

Query: 5   SYRVSSGHRVGNFSSCSAMTPQNLNRFRANSVS-CWSGPGFRGLG-------SFGSRSVI 56
           S    SG R G FS+ SA+TP    R R +SVS   S  G  GLG       SFGSRS+ 
Sbjct: 6   SITFQSGSRRG-FSTTSAITPA-AGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLY 63

Query: 57  TFGSYSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYG 116
             G  + R++  G          G+ C  GFG       G      V  GFG G G+G G
Sbjct: 64  NLGG-AKRVSINGC---------GSSCRSGFGGRASNRFG------VNSGFGYGGGVGGG 107

Query: 117 FGGPGFGYRVGGVGVPAAP--SITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNN 174
           F GP F         P  P   I  VTVN+SLLTPL+L+IDP  QRV+ +E+EQIKTLNN
Sbjct: 108 FSGPSF---------PVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNN 158

Query: 175 KFASFIDKVRFLEQQNKLLETKWSFLQEQ--KCIRSNLEPLFESYITNLRRQLEVLVSDQ 232
           KFASFIDKVRFLEQQNK+LETKW+ LQEQ  + +R NLEPLF+SY + LRRQLE + +++
Sbjct: 159 KFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTER 218

Query: 233 ARLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLT 292
            RL+AE  ++QDV+E FK +YE+E+  R  AENEFVALKKDVDAA+MNK +LEA V +L 
Sbjct: 219 GRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLP 278

Query: 293 QEIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADA 352
           +EI+F+ +++  E+  LQ+ + +TSV++ MDN+R+L+LD IIAEVKAQYE++A RSRA+A
Sbjct: 279 EEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEA 338

Query: 353 EAWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEA 412
           E+WYQTKYEE+QVTAG+H D+LRN + EI+E+ R+IQRL+AEI+  K Q + L+ A+A+A
Sbjct: 339 ESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADA 398

Query: 413 EQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGE 472
           EQ+GE  L DA+ KL DLE ALQ+AKQDMAR L EYQELMN KL LD+EIATYR+LLEGE
Sbjct: 399 EQRGELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGE 458

Query: 473 ESRLC-EGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCG 531
           E RL  EGV PVNISV +S      G     +GS++  G +   G S    T+    S G
Sbjct: 459 ECRLSGEGVSPVNISVVTSTLSSGYG-----SGSSIGGGNLGLGGGSGYSFTTSGGHSLG 513

Query: 532 PSLGGARVAPATGDLLSTGTRSGSMLISEACVPSVPCPLPTQGGFSSCS----GGRSSSV 587
             LGG+                                     GFS+ S    GG  SSV
Sbjct: 514 AGLGGS-------------------------------------GFSATSNRGLGGSGSSV 536

Query: 588 RFVSTTTSCRTKY 600
           +FVSTT+S +  Y
Sbjct: 537 KFVSTTSSSQKSY 549


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  482 bits (1240), Expect = e-136
 Identities = 295/593 (49%), Positives = 374/593 (63%), Gaps = 46/593 (7%)

Query: 43  GFR-GLGSFGSRSVITFGSY----------SPRIAAVGSRPIHCGVR------FGAGCGM 85
           GFR G GSFGSRS+   GS           S R    G     CG        FG   G 
Sbjct: 45  GFRSGAGSFGSRSLYNLGSNKSISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGG 104

Query: 86  GFGDGRGVGLGPRADSCVGLGFGAGSGIGYG--FGGPGFGYRVGGVGVPAAPS-ITAVTV 142
           GFG GRGVG G         GFG   G G    FGGPG     GG G    P  I  V V
Sbjct: 105 GFGGGRGVGSGFGGAG----GFGGAGGFGGPGVFGGPGSFGGPGGFGPGGFPGGIQEVIV 160

Query: 143 NKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQE 202
           N+SLL PLN+EIDP   +VK  E+EQIKTLNNKFASFIDKVRFLEQQNK+LETKW  LQ+
Sbjct: 161 NQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQ 220

Query: 203 QKCIR--SNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCR 260
           Q      S+LEP FESYI+ L +QL+ L+ ++  L+ E   +QD++E FKKKYE+E+  R
Sbjct: 221 QTTGSGPSSLEPCFESYISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKR 280

Query: 261 ANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIV 320
             AENEFV LKKDVDAAFMNK +L+A VD+LT E+ FL+TLY  E+  +QSH S+TSV++
Sbjct: 281 TAAENEFVGLKKDVDAAFMNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVL 340

Query: 321 KMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNE 380
            MDN+R L+L  IIAEV+AQYEE+A+RS+++AEA YQTK  E+Q TAG+H D+LRN ++E
Sbjct: 341 SMDNNRCLDLGSIIAEVRAQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSE 400

Query: 381 INELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQD 440
           I EL R+IQRL+AEIE+ K Q A L+ A+AEAEQ+GE  L DA  KL DL+ ALQ+AK D
Sbjct: 401 IMELNRMIQRLRAEIENVKKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDD 460

Query: 441 MARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRL---CEGVGPVNI--SVSSSRGGLV 495
           +AR L +YQELMN KL LD+EIATYR+LLEGEE R+   C+    +++  +V+S+ G   
Sbjct: 461 LARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGECQSAVCISVVSNVTSTSGS-- 518

Query: 496 CGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSLG---------GARVAPATGDL 546
            G    V G     G   + G SS  ++SG   S G   G         G R +  +   
Sbjct: 519 SGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQS 578

Query: 547 LSTGTR---SGSMLISEACVPSVPCPLPTQGGFS-SCSGGRSSSVRFVSTTTS 595
            S+G+R   +GS+ +S + + S    + T GG      GG S+S+RF  TT+S
Sbjct: 579 SSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKSGGGGSTSIRFSQTTSS 631


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  472 bits (1214), Expect = e-133
 Identities = 304/655 (46%), Positives = 392/655 (59%), Gaps = 72/655 (10%)

Query: 4   RSYRVSSGHRVGN-FSSCSAMTPQNLNRFRANSV-----------SCWSGPGFRGLGS-F 50
           R +   SG+R G  FSS SA       R  ++S            SC  G G  G G  F
Sbjct: 3   RQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGF 62

Query: 51  GSRSVITFG---SYSPRIAAVGSRPIHCGVRFGAGC--GMGFGDGRGVGLGPRADSCVGL 105
           GSRS++  G   S S  +A  G R    G  +G G   G GFG G   G G       G 
Sbjct: 63  GSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGF 122

Query: 106 GFGAGSGIGYGFGGPGFGYRVGGVGVPAAPS-ITAVTVNKSLLTPLNLEIDPNAQRVKKD 164
           G G G   G GFGG G+G   GG G    P  I  VT+N+SLL PLN+EIDP  Q+VK  
Sbjct: 123 GSGGGGFGGGGFGGGGYG---GGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSR 179

Query: 165 EKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQE--QKCIRSNLEPLFESYITNLR 222
           E+EQIK+LNN+FASFIDKVRFLEQQN++L+TKW  LQ+        NLEP FES+I NLR
Sbjct: 180 EREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLR 239

Query: 223 RQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKS 282
           R+++ L SDQ+RL +E  ++QD++E ++ KYE+E+  R NAENEFV +KKDVD A+M K 
Sbjct: 240 RRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKV 299

Query: 283 DLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYE 342
           DL+A +D L QEIDFL  LY  E+  +Q+ ISET+VI+ MDN+R L+LD IIAEVKAQYE
Sbjct: 300 DLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYE 359

Query: 343 EVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQR 402
           ++A++S+A+AE+ YQ+KYEE+Q+TAG+H D++RN + EI+EL R+IQRL++EI++ K Q 
Sbjct: 360 DIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQI 419

Query: 403 AKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEI 462
           + L+ ++++AEQ+GE  L DAK KL DLE ALQQAK+D+AR L +YQELMN KL LD+EI
Sbjct: 420 SNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEI 479

Query: 463 ATYRRLLEGEESRLCEGVGP-VNISVSSSRGGLVCGPEPLVAGSTLSRGGVTF------- 514
           ATYR LLEGEESR+     P V++SVS+S   +  G      G     GG ++       
Sbjct: 480 ATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSY 539

Query: 515 --------------SGSSSVCATSGVLAS-----------CGPSLGGARVAPATGDLLST 549
                         SG SS  +  G   S            G S GG R     G   S+
Sbjct: 540 GSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSS 599

Query: 550 GTRSGSMLISEACVPSVPCPLPTQGGFSSCSGG-----RSSSVRFVSTTTSCRTK 599
           G R      S   +          GG  S SGG      SSSV+FVSTT S  T+
Sbjct: 600 GGRGSGGGSSGGSI----------GGRGSSSGGVKSSGGSSSVKFVSTTYSGVTR 644


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  468 bits (1205), Expect = e-132
 Identities = 297/622 (47%), Positives = 375/622 (60%), Gaps = 64/622 (10%)

Query: 1   MSCRSYRVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSGP-GFR-GLGSFGSRSVITF 58
           MS ++ + S G   G     + ++  +     A+S     G  GFR G G FGSRS+   
Sbjct: 1   MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNL 60

Query: 59  G---SYSPRIAAVGSRP-------IHC----------GVRFGAGCGMGFGDGRGVGLGPR 98
           G   S S  +AA GSR          C          G  +G G G GFG GRG+G G  
Sbjct: 61  GGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFG 120

Query: 99  ADSCVGL--GFGAGSGIGY--------GFGGPGFGYRVGGVGVPAAPS-ITAVTVNKSLL 147
                G   GFG   G G         GFGGPG     GG G    P  I  VT+N+SLL
Sbjct: 121 GAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLL 180

Query: 148 TPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQEQKCIR 207
            PLN+EIDP   +VK  E+EQIKTLNNKFASFIDKVRFLEQQNK+LETKW+ LQ+Q    
Sbjct: 181 QPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSS 240

Query: 208 ----SNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANA 263
               +NLEPLFE++I  LR  L+ ++ ++ RL +E  +++D++E FKKKYE+E+  R  A
Sbjct: 241 ISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAA 300

Query: 264 ENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIVKMD 323
           ENEFV LKKDVD+A+MNK +L+A VD L  EIDFL+TLY  E+  +QSHIS+TSV++ MD
Sbjct: 301 ENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMD 360

Query: 324 NSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINE 383
           N+R L+LD IIAEV+AQYE++A+RS+A+AEA YQTK  E+Q TAG+H D+LRN ++EI E
Sbjct: 361 NNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIE 420

Query: 384 LTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMAR 443
           L R+IQRL+AEIE  K Q A L+ A+AEAEQ GE  L DA  KL +L+ ALQQAK D+AR
Sbjct: 421 LNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLAR 480

Query: 444 QLCEYQELMNAKLGLDIEIATYRRLLEGEESRLC-EGVGPVNISVSSSR----------- 491
            L +YQELMN KL LD+EIATYR+LLEGEE R+  E    V+ISV SS            
Sbjct: 481 LLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGG 540

Query: 492 -----------GGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCG-PSLGGARV 539
                      GG   G     +GS   RGG    G      +SG     G  S+ GAR 
Sbjct: 541 GYGGGMGGGLGGGFSAGGG---SGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGARY 597

Query: 540 APATGDLLSTGTRSGSMLISEA 561
             + G   S   R GS+  S++
Sbjct: 598 GVSGGGFSSASNRGGSIKFSQS 619


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  468 bits (1203), Expect = e-132
 Identities = 259/430 (60%), Positives = 313/430 (72%), Gaps = 4/430 (0%)

Query: 92  GVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGYRVGGVGVPAAPSITAVTVNKSLLTPLN 151
           G G   R  S    G G+ S  G G   P    R    G P    I  VT+N+SLL PL 
Sbjct: 19  GRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVR-SAYGGPVGAGIREVTINQSLLAPLR 77

Query: 152 LEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQEQKCIRSNLE 211
           L+ DP+ QRV+++E EQIKTLNNKFASFIDKVRFLEQQNKLLETKW+ LQEQK  +S+  
Sbjct: 78  LDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRL 137

Query: 212 P-LFESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVAL 270
           P +FE+ I  LR QLE L  D  RL+AE   +QDV+E FK KYE+E+  R  AENEFV L
Sbjct: 138 PDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVL 197

Query: 271 KKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNL 330
           KKDVDAA+M+K +LEA VD L  EI+FL+TL   E+  LQS IS+TSV++ MDNSR L+L
Sbjct: 198 KKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDL 257

Query: 331 DGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQR 390
           DGIIAEVKAQYEE+A+ SRA+AEAWYQTK+E +Q  AG+H D+LRN RNEI+E+ R IQR
Sbjct: 258 DGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQR 317

Query: 391 LKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQE 450
           L+AEI++ K QRAKLEAA+AEAE++GE  L DA+ K  +LE ALQ+ KQDMARQL EYQE
Sbjct: 318 LQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQE 377

Query: 451 LMNAKLGLDIEIATYRRLLEGEESRLC-EGVGPVNISVSSSRGGLVCGPE-PLVAGSTLS 508
           LM+ KL LDIEIATYR+LLEGEESRL  +GVG VNISV +S GG   G    L  G T+ 
Sbjct: 378 LMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGIGLTLGGTMG 437

Query: 509 RGGVTFSGSS 518
              ++FS S+
Sbjct: 438 SNALSFSSSA 447


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  458 bits (1179), Expect = e-129
 Identities = 280/553 (50%), Positives = 349/553 (63%), Gaps = 55/553 (9%)

Query: 15  GNFSSCSAMT---PQNLNRFRANSVSCWSGPGFR-----GLGSFGSRSVITFGSYSPRIA 66
           G FSS SA      Q    F + +VS  SG G       G G FGSRS+   G       
Sbjct: 14  GGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSLYNLG------- 66

Query: 67  AVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGYRV 126
             G + I   V  GA  G   G               G GFG+ + +G G G   FG   
Sbjct: 67  --GHKSISVSVAGGALLGRALG---------------GFGFGSRAFMGQGAGRQTFG--- 106

Query: 127 GGVGVPAAP--SITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVR 184
                PA P   I  VTVN+SLLTPL++EIDP  QRV+  E+EQIKTLNNKFASFIDKVR
Sbjct: 107 -----PACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVR 161

Query: 185 FLEQQNKLLETKWSFLQEQK----CIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERN 240
           FLEQQNK+LETKW+ LQEQ       R+NLEPLFE+Y+ ++R  L+ L S++ RL +E  
Sbjct: 162 FLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELR 221

Query: 241 HLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKT 300
           ++QD++E FK KYE+E+     AENEFV LKKDVDAA+M + DL   V TLTQEIDFL+ 
Sbjct: 222 NVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQ 281

Query: 301 LYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKY 360
           LY  E+  +Q+H+S T+V++ MDN+R+L+LD IIAEVKAQYE +A+RSRA+AEAWYQTKY
Sbjct: 282 LYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKY 341

Query: 361 EEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATL 420
           EE+QVTAG+H DNLR+ +NEI ELTR IQRL+ E + AK Q  +L+ A+AEAEQ+GE  L
Sbjct: 342 EELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELAL 401

Query: 421 SDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGV 480
            DA+ KL DL+ AL QAK+D+ R L +YQELMN KL LD+EIATYR+LLE EESR+  G 
Sbjct: 402 KDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRM-SGE 460

Query: 481 GPVNISVS-SSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPS-LGGAR 538
            P  +S+S +     VCG      G   S GG    G S      G   + G S + G  
Sbjct: 461 CPSAVSISVTGNSTTVCG------GGAASFGGGISLGGSGGATKGGFSTNVGYSTVKGGP 514

Query: 539 VAPATGDLLSTGT 551
           V+  T  L  T T
Sbjct: 515 VSAGTSILRKTTT 527


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  457 bits (1176), Expect = e-128
 Identities = 257/449 (57%), Positives = 316/449 (70%), Gaps = 28/449 (6%)

Query: 96  GPRADSCVGLGFGAGSGIGYGF----------GGPGFGYRVGGVGVPAAPSITAVTVNKS 145
           GPRA S      G GS I              GG G GY     G      ITAVTVN+S
Sbjct: 16  GPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYG----GASGMGGITAVTVNQS 71

Query: 146 LLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQEQKC 205
           LL+PL LE+DPN Q V+  EKEQIKTLNNKFASFIDKVRFLEQQNK+LETKWS LQ+QK 
Sbjct: 72  LLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKT 131

Query: 206 IRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANAEN 265
            RSN++ +FESYI NLRRQLE L  ++ +L+AE  ++Q ++E FK KYE+E+  R   EN
Sbjct: 132 ARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMEN 191

Query: 266 EFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIVKMDNS 325
           EFV +KKDVD A+MNK +LE+ ++ LT EI+FL+ LY EEI+ LQS IS+TSV++ MDNS
Sbjct: 192 EFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDNS 251

Query: 326 RDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINELT 385
           R L++D IIAEVKAQYE++A RSRA+AE+ YQ KYEE+Q  AG+H D+LR  + EI+E+ 
Sbjct: 252 RSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMN 311

Query: 386 RLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMARQL 445
           R I RL+AEIE  K QRA LEAA+A+AEQ+GE  + DA  KL++LE ALQ+AKQDMARQL
Sbjct: 312 RNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQL 371

Query: 446 CEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVNI----------SVSSSRGGLV 495
            EYQELMN KL LDIEIATYR+LLEGEESRL  G+  ++I           +SS+ GGL 
Sbjct: 372 REYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSGYAGGLSSAYGGLT 431

Query: 496 CGPEPLVAGSTLSRGGVTFSGSSSVCATS 524
                   GS+   G    +GSSS   TS
Sbjct: 432 SPGLSYSLGSSFGSG----AGSSSFSRTS 456


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  451 bits (1161), Expect = e-127
 Identities = 262/525 (49%), Positives = 348/525 (66%), Gaps = 41/525 (7%)

Query: 19  SCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITF-GSYSPRIAAVGSRPIHCGV 77
           SC +       R   +SVS   G G    G FGSRS+    G+ S  ++  GSR   C  
Sbjct: 90  SCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGAC-- 147

Query: 78  RFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGY-GFGGPGFGYRVGGVGVPAAPS 136
                    FG   G G G         GFG G G  + G GGPGF        V  A  
Sbjct: 148 ---------FGGAGGFGTG---------GFGGGFGGSFSGKGGPGFP-------VCPAGG 182

Query: 137 ITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETK 196
           I  VT+N+SLLTPL++EIDP  Q+V+ +E+EQIK LNNKFASFIDKV+FLEQQNK+LETK
Sbjct: 183 IQEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETK 242

Query: 197 WSFLQEQKCIRS--NLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYE 254
           W+ LQ+Q    S  NLEPLFE+Y++ LR+QL+ L +D+ RLQ+E   +QD +E FK KYE
Sbjct: 243 WNLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYE 302

Query: 255 EEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHIS 314
           EE+  R  AEN+FV LKKDVDAA++NK +LEA VD+L  EI+FLK LY  E+  +Q+H+S
Sbjct: 303 EEINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVS 362

Query: 315 ETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNL 374
           +TSV++ MDN+R+L+LD IIAEV+AQYEE+A+RS+A+AEA YQTK +++Q++  QH DNL
Sbjct: 363 DTSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNL 422

Query: 375 RNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECAL 434
           +N ++EI EL R+IQRL+AEIE+ K Q   L+ +VA+AEQ+GE  L DA  K  +LE AL
Sbjct: 423 KNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAAL 482

Query: 435 QQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRL---CEGVGPVNISVSSSR 491
           QQAK+++AR L EYQELM+ KL LDIEIATYR+LLEGEE R+   C+    +++   S+ 
Sbjct: 483 QQAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTS 542

Query: 492 GGLVCGPEPLVAGSTLSRG-------GVTFSGSSSVCATSGVLAS 529
            G + G     +G  LS G       G  F GS S  ++S ++++
Sbjct: 543 TGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGSSSSKIIST 587


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  444 bits (1141), Expect = e-124
 Identities = 276/565 (48%), Positives = 358/565 (63%), Gaps = 35/565 (6%)

Query: 1   MSCRSY-RVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWS-----GPGFRGLGSFGSRS 54
           +SC+S  R   G     FSS SA+      R   +S SC S     G GF G G FGSRS
Sbjct: 5   ISCKSRGRGGGGGGFRGFSSGSAVVSGGSRR-STSSFSCLSRHGGGGGGFGG-GGFGSRS 62

Query: 55  VITFG-SYSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGI 113
           ++  G + S  I+  G      G  FGA  G G   GRG G G  +    G GF  G   
Sbjct: 63  LVGLGGTKSISISVAGG-----GGGFGAAGGFG---GRGGGFGGGSSFGGGSGFSGGGFG 114

Query: 114 GYGFGGPGFGY-----RVGGVGVPAA-------PSITAVTVNKSLLTPLNLEIDPNAQRV 161
           G GFGG  FG       VGG+G P           I  V+VN+SLL PLN+++DP  Q V
Sbjct: 115 GGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNV 174

Query: 162 KKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQEQKCIRS--NLEPLFESYIT 219
           K  E+EQIKTLNNKFASFIDKVRFLEQQN++L+TKW  LQ+        NLEP+F+ YI 
Sbjct: 175 KAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYID 234

Query: 220 NLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFM 279
           +L+R L+ L +++    +E N++QD++E +KKKYE+E+  R  AEN+FV LKKDVD A+M
Sbjct: 235 SLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYM 294

Query: 280 NKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKA 339
            K +L++ VD L QEI+FLK LY  EI  +   +++T+VI+ MDNSR+L+LD IIAEVKA
Sbjct: 295 IKVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKA 354

Query: 340 QYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAK 399
           QYEE+A+RS+ +AEA Y +KYEE+QVT G+H D+L+ I+ EI+EL R+IQRL+ EI H K
Sbjct: 355 QYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVK 414

Query: 400 AQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLD 459
            Q   ++ A+A+AEQ+GE  L DA+ KL DLE ALQQAK+D+AR L +YQELMN KL LD
Sbjct: 415 KQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALD 474

Query: 460 IEIATYRRLLEGEESRLCEGVGP-VNISVSSSRGGLVCGPEPLVAGS---TLSRGGVTFS 515
           +EIATYR+LLEGEE R+   +   V +SV+SS        +    GS     S GG   S
Sbjct: 475 VEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSS 534

Query: 516 GSSSVCATSGVLASCGPSLGGARVA 540
           GSSS  +      S G S GG  ++
Sbjct: 535 GSSSYGSGGRQSGSRGGSGGGGSIS 559



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 36/100 (36%), Positives = 41/100 (41%), Gaps = 17/100 (17%)

Query: 48  GSFGSRSVITFGSYSPRIAAVGSRPIHCGVRFGAGCG---MGFGDGRGVGLGPRADSCVG 104
           G  G R   + G YS   ++ GS     G R G+G G    G G G G G G R  S  G
Sbjct: 519 GGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGG 578

Query: 105 LGFGAGSGIGYGFGG--------------PGFGYRVGGVG 130
              G+ SG GYG GG               G GY  GG G
Sbjct: 579 SKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGG 618


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  440 bits (1131), Expect = e-123
 Identities = 262/531 (49%), Positives = 346/531 (65%), Gaps = 47/531 (8%)

Query: 4   RSYRVSSGHRV-GNFSSCSA-MTPQNLNRFRANSVSCWSGPGFRGL-GSFGSRSVITFGS 60
           R +   SG    G FS CSA ++  + + FRA S         +GL G FGSRS+ + G 
Sbjct: 3   RQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGS---------KGLSGGFGSRSLYSLGG 53

Query: 61  YSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGP 120
                 A GS         G   G GFG GR  G                   G  FG  
Sbjct: 54  VRSLNVASGS---------GKSGGYGFGRGRASGFA-----------------GSMFGSV 87

Query: 121 GFGYRVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFI 180
             G     V  P    I  VTVN+SLL PLN+E+DP  Q+V+  E+EQIK LNNKFASFI
Sbjct: 88  ALGPVCPTVCPPGG--IHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFI 145

Query: 181 DKVRFLEQQNKLLETKWSFLQE---QKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQA 237
           DKVRFLEQQN++LETKW  LQ+     C ++NLEP+ E YI+NLR+QLE L  D+ RL +
Sbjct: 146 DKVRFLEQQNQVLETKWELLQQLDLNNC-KNNLEPILEGYISNLRKQLETLSGDRVRLDS 204

Query: 238 ERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDF 297
           E  +++DV+E +KK+YEEE+  R  AENEFV LKKDVDAA+ NK +L+A V+++ QEI F
Sbjct: 205 ELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKF 264

Query: 298 LKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQ 357
            + L+  EI  +QSHIS+ SVI+ MDN+R+L+LD II EV+ QYEE+A +S+A+AEA YQ
Sbjct: 265 FRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQ 324

Query: 358 TKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGE 417
           TK++E+Q+ AG+H D+L+N +NEI+ELTRLIQR+++EIE+ K Q + LE A+A+AEQ+G+
Sbjct: 325 TKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGD 384

Query: 418 ATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLC 477
             L DA+ KL +LE AL QAK+++AR L EYQELM+ KL LD+EIATYR+LLE EE R+ 
Sbjct: 385 NALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMS 444

Query: 478 -EGVGPVNIS-VSSSRGGLVCGPEP-LVAGSTLSRGGVTFSGSSSVCATSG 525
            E   PV+IS +SS+ GG V G  P +V+G  ++      SG  SV    G
Sbjct: 445 GEFPSPVSISIISSTSGGSVYGFRPSMVSGGYVANSSNCISGVCSVRGGEG 495


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score =  439 bits (1130), Expect = e-123
 Identities = 257/500 (51%), Positives = 333/500 (66%), Gaps = 46/500 (9%)

Query: 4   RSYRVSSGHRV-GNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFGSYS 62
           R +   SG    G FS CSA+           S S +   G    G F SRS+ + G   
Sbjct: 3   RQFTYKSGAAAKGGFSGCSAV-------LSGGSSSSYRAGGKGLSGGFSSRSLYSLG--- 52

Query: 63  PRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGF 122
                 G+R I   V  G+G   G+G GRG     RA                GF G  F
Sbjct: 53  ------GARSISFNVASGSGWAGGYGFGRG-----RAS---------------GFAGSMF 86

Query: 123 G-YRVGGVGVPAAP--SITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASF 179
           G   +G V     P   I  VT+NKSLL PLN+E+DP  Q+V+  E+EQIK LNNKFASF
Sbjct: 87  GSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASF 146

Query: 180 IDKVRFLEQQNKLLETKWSFLQE---QKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQ 236
           IDKVRFLEQQN++LETKW  LQ+     C ++NLEP+ E YI+NLR+QLE L  D+ RL 
Sbjct: 147 IDKVRFLEQQNQVLETKWELLQQLDLNNC-KNNLEPILEGYISNLRKQLETLSGDRVRLD 205

Query: 237 AERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEID 296
           +E   +++V+E +KK+YEEE+  R  AENEFV LKKDVDAA+ +K +L+A VD L  EI 
Sbjct: 206 SELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIK 265

Query: 297 FLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWY 356
           F K LY  E   +QSHIS+TS+I+ MDN+R+L+LD IIAEV+AQYEE+AR+S+A+AEA Y
Sbjct: 266 FFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALY 325

Query: 357 QTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQG 416
           QTK++E+Q+ AG+H D+L++ +NEI+ELTRLIQRL++EIE  K Q A LE A+A+AEQ+G
Sbjct: 326 QTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQRG 385

Query: 417 EATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRL 476
           +  L DA+ KL +LE ALQQAK+++AR L EYQEL++ KL LDIEIATYR+LLEGEE R+
Sbjct: 386 DCALKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRM 445

Query: 477 C-EGVGPVNISV-SSSRGGL 494
             E    V+ISV +SS  G+
Sbjct: 446 SGEYTNSVSISVINSSMAGM 465


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  431 bits (1108), Expect = e-121
 Identities = 258/528 (48%), Positives = 335/528 (63%), Gaps = 50/528 (9%)

Query: 11  GHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFGSYSPRIAAVGS 70
           G R+G FS CSA+    +      S S       +G  SFGS+S+   G    R  A+ +
Sbjct: 11  GERLG-FSGCSAVLSGGIG-----SSSASFRARVKGSASFGSKSLSCLGG--SRSLALSA 62

Query: 71  RPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGYRVGGVG 130
                G R G   G  FG     GLGP+  S    G                       G
Sbjct: 63  AARRGGGRLGGFVGTAFGSA---GLGPKCPSVCPPG-----------------------G 96

Query: 131 VPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQN 190
           +P       VTVNKSLL PLN+E+DP  QRV+  E+EQIK LNNKFASFIDKVRFLEQQN
Sbjct: 97  IPQ------VTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQN 150

Query: 191 KLLETKWSFLQE---QKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLE 247
           ++LETKW+ LQ+     C R NLEP++E YI+NL++QLE+L  D  RL +E  ++QD++E
Sbjct: 151 QVLETKWNLLQQLDLNNC-RKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVE 209

Query: 248 GFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQ 307
            +KK+YE E+  R  AENEFV LKKDVDAA+MNK +L+A VD+LT EI F K LY  EI 
Sbjct: 210 DYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEIT 269

Query: 308 LLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTA 367
            +QSHIS+TS+++ MDN+RDL+LD IIAEV+AQYEE+A +S+A+AE  YQTK +E+QVTA
Sbjct: 270 QIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTA 329

Query: 368 GQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKL 427
           GQH D+L+  + EI+EL RLIQR+++EI + K Q A LE A+A+AEQ+G+  L DA+ KL
Sbjct: 330 GQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKL 389

Query: 428 ADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLC-EGVGPVNIS 486
            +LE AL QAK+++AR L EYQEL++ KL LD+EIATYR+LLE EE R+  E    V+IS
Sbjct: 390 DELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSIS 449

Query: 487 VSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSL 534
           V SS      G     AG ++  G  +     +  A      SCG  L
Sbjct: 450 VISSTNAGAGG-----AGFSMGFGASSSYSYKTAAADVKTKGSCGSEL 492


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  431 bits (1108), Expect = e-121
 Identities = 258/528 (48%), Positives = 335/528 (63%), Gaps = 50/528 (9%)

Query: 11  GHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFGSYSPRIAAVGS 70
           G R+G FS CSA+    +      S S       +G  SFGS+S+   G    R  A+ +
Sbjct: 11  GERLG-FSGCSAVLSGGIG-----SSSASFRARVKGSASFGSKSLSCLGG--SRSLALSA 62

Query: 71  RPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGYRVGGVG 130
                G R G   G  FG     GLGP+  S    G                       G
Sbjct: 63  AARRGGGRLGGFVGTAFGSA---GLGPKCPSVCPPG-----------------------G 96

Query: 131 VPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQN 190
           +P       VTVNKSLL PLN+E+DP  QRV+  E+EQIK LNNKFASFIDKVRFLEQQN
Sbjct: 97  IPQ------VTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQN 150

Query: 191 KLLETKWSFLQE---QKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLE 247
           ++LETKW+ LQ+     C R NLEP++E YI+NL++QLE+L  D  RL +E  ++QD++E
Sbjct: 151 QVLETKWNLLQQLDLNNC-RKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVE 209

Query: 248 GFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQ 307
            +KK+YE E+  R  AENEFV LKKDVDAA+MNK +L+A VD+LT EI F K LY  EI 
Sbjct: 210 DYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEIT 269

Query: 308 LLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTA 367
            +QSHIS+TS+++ MDN+RDL+LD IIAEV+AQYEE+A +S+A+AE  YQTK +E+QVTA
Sbjct: 270 QIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTA 329

Query: 368 GQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKL 427
           GQH D+L+  + EI+EL RLIQR+++EI + K Q A LE A+A+AEQ+G+  L DA+ KL
Sbjct: 330 GQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKL 389

Query: 428 ADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLC-EGVGPVNIS 486
            +LE AL QAK+++AR L EYQEL++ KL LD+EIATYR+LLE EE R+  E    V+IS
Sbjct: 390 DELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSIS 449

Query: 487 VSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSL 534
           V SS      G     AG ++  G  +     +  A      SCG  L
Sbjct: 450 VISSTNAGAGG-----AGFSMGFGASSSYSYKTAAADVKTKGSCGSEL 492


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  427 bits (1098), Expect = e-119
 Identities = 267/557 (47%), Positives = 348/557 (62%), Gaps = 49/557 (8%)

Query: 4   RSYRVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGS-FGSRSVITFGSYS 62
           R   + S    GNFS  SA+ P    R    S++ +   G RG G+ FGSRS+ + G   
Sbjct: 3   RQLNIKSSGDKGNFSVHSAVVP----RKAVGSLASYCAAG-RGAGAGFGSRSLYSLG--- 54

Query: 63  PRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGF 122
                 G+R I   V   AG G+  G   G G  P        G G G G   GF G  F
Sbjct: 55  ------GNRRISFNV---AGGGVRAG---GYGFRP--------GSGYGGGRASGFAGSMF 94

Query: 123 G-YRVGGVGVPAAP--SITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASF 179
           G   +G   +   P   I  VTVNKSLL PLN+E+DP  Q+V+  E+EQIK LN+KFASF
Sbjct: 95  GSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASF 154

Query: 180 IDKVRFLEQQNKLLETKWSFLQE---QKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQ 236
           IDKVRFLEQQN++LETKW  LQ+     C + NLEP+ E YI+NLR+QLE L  D+ RL 
Sbjct: 155 IDKVRFLEQQNQVLETKWELLQQLDLNNC-KKNLEPILEGYISNLRKQLETLSGDRVRLD 213

Query: 237 AERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEID 296
           +E   ++D++E +KK+YE E+  R  AENEFV LKKD DAA+  K +L+A VD+L +EI 
Sbjct: 214 SELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLDKEIK 273

Query: 297 FLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWY 356
           FLK LY  EI  +Q+H SETSVI+ MDN+RDL+LD IIAEV+  YEE+A +S+A+AEA Y
Sbjct: 274 FLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALY 333

Query: 357 QTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQG 416
           QTK +E+Q+ A +H D+L++ R+E+ EL RLIQR++ EI + K QRA LE A+A+AEQ+G
Sbjct: 334 QTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADAEQRG 393

Query: 417 EATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRL 476
           +  L DA+ KL +LE AL QAK+++AR L EYQELM+ KL LD+EIATYR+LLEGEE R+
Sbjct: 394 DNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGEECRM 453

Query: 477 CEGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSLGG 536
             G  P ++S+S           P  AG  L        G+S+V  +SG   S       
Sbjct: 454 -SGENPSSVSISVISSSSYSYHHPSSAGVDL--------GASAVAGSSGSTQSGQTKTTE 504

Query: 537 ARVAPATGDLLSTGTRS 553
           AR     GDL  T  +S
Sbjct: 505 AR----GGDLKDTQGKS 517


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  425 bits (1093), Expect = e-119
 Identities = 264/563 (46%), Positives = 353/563 (62%), Gaps = 48/563 (8%)

Query: 41  GPGFRGLGSFGSRSVITFG-SYSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRA 99
           G G  G G FGSRS+   G S S  I  +G      G   G G G GFG GRG G+G   
Sbjct: 48  GYGIHGRG-FGSRSLYNLGGSRSISINLMGRST--SGFCQGGGVG-GFGGGRGFGVGST- 102

Query: 100 DSCVGLGFGAGSGIGYGFGGPGFG---YRVGGVGVPAAPS-ITAVTVNKSLLTPLNLEID 155
                   GAG   G GFGG GFG   + +GG G    P  I  VT+N+SLL PL+LE+D
Sbjct: 103 --------GAGGFGGGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVD 154

Query: 156 PNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQEQKCIR--SNLEPL 213
           P  QR+K  E+EQI  LNNKFASFIDKVRFLEQQN++L+TKW  LQ+       +NLEPL
Sbjct: 155 PEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPL 214

Query: 214 FESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKD 273
            E+YI +LRRQ+++L ++Q R  AE   +QDV+E +K KYE+E+  R  +EN+FV LKKD
Sbjct: 215 LENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKD 274

Query: 274 VDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGI 333
           VDAA+++K DLE+ VDTLT E++FLK L++ E+  +Q+HIS+T+VI+ MDN+R L+LD I
Sbjct: 275 VDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSI 334

Query: 334 IAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKA 393
           I  V+ QYE +A+RS+ +AEA YQTKY+E+Q+TAG+H D+L+N + EI EL R +QRL+A
Sbjct: 335 IDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQA 394

Query: 394 EIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELMN 453
           EI + K Q  ++++ +++AE++GE  L DA  KL DLE ALQQ+K+++AR L +YQ ++ 
Sbjct: 395 EISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLG 454

Query: 454 AKLGLDIEIATYRRLLEGEESRLC-EGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRGGV 512
            KL LD+EIATYR+LLEGEESR+  E    V+ISV +S+  +  G     AG   S G  
Sbjct: 455 VKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSVNGG-----AGGGGSYGSG 509

Query: 513 TFSGSSSVCATSGVLASCGPSLGGARVAPATGDLLSTGTRSGSMLISEACVPSVPCPLPT 572
            + G S      G         GGAR     G     G   GS                 
Sbjct: 510 GYGGGSG----GGYGGGRSYRGGGARGRSGGGYGSGCGGGGGSY---------------- 549

Query: 573 QGGFSSCSGGRSSSVRFVSTTTS 595
             G S  SG  SS V+ + T+T+
Sbjct: 550 --GGSGRSGRGSSRVQIIQTSTN 570


>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score =  371 bits (953), Expect = e-103
 Identities = 238/542 (43%), Positives = 322/542 (59%), Gaps = 56/542 (10%)

Query: 17  FSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFGSYSPRIAAVGSRPIHCG 76
           FS+ SA + ++  R R          GF   G F SRS+ +FG         GSR    G
Sbjct: 12  FSARSACSARSRGRSRG---------GFSSRGGFSSRSLNSFGG-----CLEGSR----G 53

Query: 77  VRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGYRVGGVGVPAAPS 136
             +G+G       GR           +G+ FG  SG      GPG      G        
Sbjct: 54  STWGSG-------GR-----------LGVRFGEWSG------GPGLSLCPPG-------G 82

Query: 137 ITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETK 196
           I  VT+N++LLTPL +EIDP  Q V+  E ++I+TLNN+FASFIDKVRFLEQQNK+LETK
Sbjct: 83  IQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRFLEQQNKVLETK 142

Query: 197 WSFLQEQKCIRSN--LEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYE 254
           W  LQ+Q    S   LEP+FE+ +  LR+QLE L  ++  L AE    +D  E +K KYE
Sbjct: 143 WHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACRDQEEEYKSKYE 202

Query: 255 EEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHIS 314
           EE   RA  EN+FV LKKDVD  F++K +LE  ++ L + + FLK L  EE+  LQ+  S
Sbjct: 203 EEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNEEELGQLQTQAS 262

Query: 315 ETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNL 374
           +TSV++ MDN+R L+   II EV+A+YEE+AR S+A+AEA YQTKY+E+QV+A  H D +
Sbjct: 263 DTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQELQVSAQLHGDRM 322

Query: 375 RNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECAL 434
           +  + +I++L + IQRL+++ E+ K Q A L+AA+ +AEQ+GE  L DA+ K+ +LE AL
Sbjct: 323 QETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDAQAKVDELEAAL 382

Query: 435 QQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVNISVSSSRGGL 494
           + AKQ++AR LCEYQEL + KL LD+EIATYRRLLEGEE R+  G     +++SS  G  
Sbjct: 383 RMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRM-SGECTSQVTISSVGGSA 441

Query: 495 V-CGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSLGGARVAPATGDLLSTGTRS 553
           V  G      GST   G  +  GS   C TS V       LG  +  P       +G+ +
Sbjct: 442 VMSGGVGGGLGSTCGLG--SGKGSPGSCCTSIVTGGSNIILGSGK-DPVLDSCSVSGSSA 498

Query: 554 GS 555
           GS
Sbjct: 499 GS 500


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  343 bits (879), Expect = 3e-94
 Identities = 226/528 (42%), Positives = 296/528 (56%), Gaps = 92/528 (17%)

Query: 11  GHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFGSYSPRIAAVGS 70
           G R+G FS CSA+    +      S S       +G  SFGS+S+   G    R  A+ +
Sbjct: 11  GERLG-FSGCSAVLSGGIG-----SSSASFRARVKGSASFGSKSLSCLGG--SRSLALSA 62

Query: 71  RPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGYRVGGVG 130
                G R G   G  FG     GLGP+  S    G                       G
Sbjct: 63  AARRGGGRLGGFVGTAFGSA---GLGPKCPSVCPPG-----------------------G 96

Query: 131 VPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQN 190
           +P       VTVNKSLL PLN+E+DP  QRV+  E+EQIK LNNKFASFIDKVRFLEQQN
Sbjct: 97  IPQ------VTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQN 150

Query: 191 KLLETKWSFLQE---QKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLE 247
           ++LETKW+ LQ+     C R NLEP++E YI+NL++QLE+L  D  RL +E  ++QD++E
Sbjct: 151 QVLETKWNLLQQLDLNNC-RKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVE 209

Query: 248 GFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQ 307
            +KK+YE E+  R  AENEFV LKKDVDAA+MNK +L+A VD+LT EI F K LY  EI 
Sbjct: 210 DYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEIT 269

Query: 308 LLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTA 367
            +QSHIS+TS+++ MDN+RDL+LD IIAEV+AQYEE+A +S+A+AE  YQTK  +++   
Sbjct: 270 QIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKCADLETA- 328

Query: 368 GQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKL 427
                           +    QR    ++ A+A+                         L
Sbjct: 329 ----------------IADAEQRGDCALKDARAK-------------------------L 347

Query: 428 ADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLC-EGVGPVNIS 486
            +LE AL QAK+++AR L EYQEL++ KL LD+EIATYR+LLE EE R+  E    V+IS
Sbjct: 348 DELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSIS 407

Query: 487 VSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSL 534
           V SS      G     AG ++  G  +     +  A      SCG  L
Sbjct: 408 VISSTNAGAGG-----AGFSMGFGASSSYSYKTAAADVKTKGSCGSEL 450


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,368,517
Number of Sequences: 37866
Number of extensions: 1131471
Number of successful extensions: 9009
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 197
Number of HSP's successfully gapped in prelim test: 463
Number of HSP's that attempted gapping in prelim test: 5738
Number of HSP's gapped (non-prelim): 1992
length of query: 600
length of database: 18,247,518
effective HSP length: 108
effective length of query: 492
effective length of database: 14,157,990
effective search space: 6965731080
effective search space used: 6965731080
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.