BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|153791466 AMIGO protein [Homo sapiens] (493 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|153791466 AMIGO protein [Homo sapiens] 1011 0.0 gi|219521831 adhesion molecule with Ig-like domain 2 [Homo sapiens] 348 6e-96 gi|32469517 adhesion molecule with Ig-like domain 2 [Homo sapiens] 348 6e-96 gi|38454322 adhesion molecule with Ig-like domain 3 [Homo sapiens] 276 3e-74 gi|31542244 leucine rich repeat and fibronectin type III domain ... 105 9e-23 gi|126517478 peroxidasin homolog-like [Homo sapiens] 103 4e-22 gi|109150416 peroxidasin [Homo sapiens] 100 4e-21 gi|229089140 leucine rich repeat containing 24 [Homo sapiens] 99 1e-20 gi|157694513 leucine-rich repeat-containing G protein-coupled re... 96 1e-19 gi|11321571 slit homolog 3 [Homo sapiens] 95 1e-19 gi|153791330 leucine rich repeat neuronal 1 [Homo sapiens] 93 5e-19 gi|122937309 leucine rich repeat containing 4B [Homo sapiens] 93 6e-19 gi|4759146 slit homolog 2 [Homo sapiens] 89 7e-18 gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens] 89 7e-18 gi|62912470 leucine-rich repeat-containing G protein-coupled rec... 89 9e-18 gi|52138725 leucine rich repeat and Ig domain containing 4 [Homo... 88 2e-17 gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 88 2e-17 gi|188528675 slit homolog 1 [Homo sapiens] 87 3e-17 gi|15029530 leucine rich repeat containing 4 [Homo sapiens] 87 5e-17 gi|4504379 leucine-rich repeat-containing G protein-coupled rece... 86 6e-17 gi|88702793 slit-like 2 [Homo sapiens] 85 2e-16 gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens] 84 2e-16 gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens] 84 2e-16 gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens] 84 2e-16 gi|13375646 leucine rich repeat and fibronectin type III domain ... 84 3e-16 gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 81 2e-15 gi|139948432 adlican [Homo sapiens] 81 2e-15 gi|5729718 trophoblast glycoprotein [Homo sapiens] 80 4e-15 gi|113423021 PREDICTED: similar to hCG1820409 [Homo sapiens] 79 9e-15 gi|113422497 PREDICTED: similar to hCG1820409 [Homo sapiens] 79 9e-15 >gi|153791466 AMIGO protein [Homo sapiens] Length = 493 Score = 1011 bits (2615), Expect = 0.0 Identities = 493/493 (100%), Positives = 493/493 (100%) Query: 1 MHPHRDPRGLWLLLPSLSLLLFEVARAGRAVVSCPAACLCASNILSCSKQQLPNVPHSLP 60 MHPHRDPRGLWLLLPSLSLLLFEVARAGRAVVSCPAACLCASNILSCSKQQLPNVPHSLP Sbjct: 1 MHPHRDPRGLWLLLPSLSLLLFEVARAGRAVVSCPAACLCASNILSCSKQQLPNVPHSLP 60 Query: 61 SYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSN 120 SYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSN Sbjct: 61 SYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSN 120 Query: 121 QLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKE 180 QLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKE Sbjct: 121 QLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKE 180 Query: 181 GAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIKNGLYLHNNPLNCDCELYQLFSHWQYRQ 240 GAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIKNGLYLHNNPLNCDCELYQLFSHWQYRQ Sbjct: 181 GAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIKNGLYLHNNPLNCDCELYQLFSHWQYRQ 240 Query: 241 LSSVMDFQEDLYCMNSKKLHNVFNLSFLNCGEYKERAWEAHLGDTLIIKCDTKQQGMTKV 300 LSSVMDFQEDLYCMNSKKLHNVFNLSFLNCGEYKERAWEAHLGDTLIIKCDTKQQGMTKV Sbjct: 241 LSSVMDFQEDLYCMNSKKLHNVFNLSFLNCGEYKERAWEAHLGDTLIIKCDTKQQGMTKV 300 Query: 301 WVTPSNERVLDEVTNGTVSVSKDGSLLFQQVQVEDGGVYTCYAMGETFNETLSVELKVHN 360 WVTPSNERVLDEVTNGTVSVSKDGSLLFQQVQVEDGGVYTCYAMGETFNETLSVELKVHN Sbjct: 301 WVTPSNERVLDEVTNGTVSVSKDGSLLFQQVQVEDGGVYTCYAMGETFNETLSVELKVHN 360 Query: 361 FTLHGHHDTLNTAYTTLVGCILSVVLVLIYLYLTPCRCWCRGVEKPSSHQGDSLSSSMLS 420 FTLHGHHDTLNTAYTTLVGCILSVVLVLIYLYLTPCRCWCRGVEKPSSHQGDSLSSSMLS Sbjct: 361 FTLHGHHDTLNTAYTTLVGCILSVVLVLIYLYLTPCRCWCRGVEKPSSHQGDSLSSSMLS 420 Query: 421 TTPNHDPMAGGDKDDGFDRRVAFLEPAGPGQGQNGKLKPGNTLPVPEATGKGQRRMSDPE 480 TTPNHDPMAGGDKDDGFDRRVAFLEPAGPGQGQNGKLKPGNTLPVPEATGKGQRRMSDPE Sbjct: 421 TTPNHDPMAGGDKDDGFDRRVAFLEPAGPGQGQNGKLKPGNTLPVPEATGKGQRRMSDPE 480 Query: 481 SVSSVFSDTPIVV 493 SVSSVFSDTPIVV Sbjct: 481 SVSSVFSDTPIVV 493 >gi|219521831 adhesion molecule with Ig-like domain 2 [Homo sapiens] Length = 522 Score = 348 bits (893), Expect = 6e-96 Identities = 204/498 (40%), Positives = 291/498 (58%), Gaps = 24/498 (4%) Query: 17 LSLLLFEVARAGRAVVSCPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRL 76 L LL+ V A CP AC+CA++I+SC+ + L VP +L LDLS+N + L Sbjct: 24 LCLLMITVTVGPGASGVCPTACICATDIVSCTNKNLSKVPGNLFRLIKRLDLSYNRIGLL 83 Query: 77 RAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVL 136 +EW P +L++L+L HN++ IS+ +FS PNL+ LDLSSN+L+T+ +F +L+VL Sbjct: 84 DSEWIPVSFAKLNTLILRHNNITSISTGSFSTTPNLKCLDLSSNKLKTVKNAVFQELKVL 143 Query: 137 EVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNK 196 EVLLLYNNHI +D AF ++QLQKLYLS N +++FP++L KL +L LD+S N+ Sbjct: 144 EVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQFPMDLYVGRFKLAELMFLDVSYNR 203 Query: 197 LKNLPLPDLQKLPAWIKNGLYLHNNPLNCDCELYQLFSHWQYRQLSSVMDFQEDLYC--- 253 + ++P+ + +P G+YLH NP CDC LY L W R SSVMDF+ D C Sbjct: 204 IPSMPMHHINLVPGKQLRGIYLHGNPFVCDCSLYSLLVFWYRRHFSSVMDFKNDYTCRLW 263 Query: 254 MNSKKLHNVFNL--SFLNC------GEYKERAW--EAHLGDTLIIKCDTKQQGMTK--VW 301 +S+ V L SF+NC G ++ + EA +G+ L++ CD+K +W Sbjct: 264 SDSRHSRQVLLLQDSFMNCSDSIINGSFRALGFIHEAQVGERLMVHCDSKTGNANTDFIW 323 Query: 302 VTPSNERVLDEVTNGTVSVSKDGSLLFQQVQVEDGGVYTCYAMGE--TFNETLSVELKVH 359 V P N + + V +GSL+ + + ED GVY+C AM + NET+ V + V Sbjct: 324 VGPDNRLLEPDKEMENFYVFHNGSLVIESPRFEDAGVYSCIAMNKQRLLNETVDVTINVS 383 Query: 360 NFTL-HGH-HDTLNTAYTTLVGCILSVVLVLIYLYLTPCRCWCRGVEKPSSHQGDSLSSS 417 NFT+ H H+ NTA+TTL C+ S+VLVL+YLYLTPC C C+ + + + SS Sbjct: 384 NFTVSRSHAHEAFNTAFTTLAACVASIVLVLLYLYLTPCPCKCKTKRQKNMLHQSNAHSS 443 Query: 418 MLSTTPNHDPMAGGDKDDGFDRRVAFLEP-AGPGQGQNGKLK--PGNTLPVPEATGKGQR 474 +LS P D A ++ G +RV FLEP GQNGK++ P + + E K R Sbjct: 444 ILSPGPASDASA-DERKAGAGKRVVFLEPLKDTAAGQNGKVRLFPSEAV-IAEGILKSTR 501 Query: 475 RMSDPESVSSVFSDTPIV 492 SD +SV+SVFSDTP V Sbjct: 502 GKSDSDSVNSVFSDTPFV 519 >gi|32469517 adhesion molecule with Ig-like domain 2 [Homo sapiens] Length = 522 Score = 348 bits (893), Expect = 6e-96 Identities = 204/498 (40%), Positives = 291/498 (58%), Gaps = 24/498 (4%) Query: 17 LSLLLFEVARAGRAVVSCPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRL 76 L LL+ V A CP AC+CA++I+SC+ + L VP +L LDLS+N + L Sbjct: 24 LCLLMITVTVGPGASGVCPTACICATDIVSCTNKNLSKVPGNLFRLIKRLDLSYNRIGLL 83 Query: 77 RAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVL 136 +EW P +L++L+L HN++ IS+ +FS PNL+ LDLSSN+L+T+ +F +L+VL Sbjct: 84 DSEWIPVSFAKLNTLILRHNNITSISTGSFSTTPNLKCLDLSSNKLKTVKNAVFQELKVL 143 Query: 137 EVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNK 196 EVLLLYNNHI +D AF ++QLQKLYLS N +++FP++L KL +L LD+S N+ Sbjct: 144 EVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQFPMDLYVGRFKLAELMFLDVSYNR 203 Query: 197 LKNLPLPDLQKLPAWIKNGLYLHNNPLNCDCELYQLFSHWQYRQLSSVMDFQEDLYC--- 253 + ++P+ + +P G+YLH NP CDC LY L W R SSVMDF+ D C Sbjct: 204 IPSMPMHHINLVPGKQLRGIYLHGNPFVCDCSLYSLLVFWYRRHFSSVMDFKNDYTCRLW 263 Query: 254 MNSKKLHNVFNL--SFLNC------GEYKERAW--EAHLGDTLIIKCDTKQQGMTK--VW 301 +S+ V L SF+NC G ++ + EA +G+ L++ CD+K +W Sbjct: 264 SDSRHSRQVLLLQDSFMNCSDSIINGSFRALGFIHEAQVGERLMVHCDSKTGNANTDFIW 323 Query: 302 VTPSNERVLDEVTNGTVSVSKDGSLLFQQVQVEDGGVYTCYAMGE--TFNETLSVELKVH 359 V P N + + V +GSL+ + + ED GVY+C AM + NET+ V + V Sbjct: 324 VGPDNRLLEPDKEMENFYVFHNGSLVIESPRFEDAGVYSCIAMNKQRLLNETVDVTINVS 383 Query: 360 NFTL-HGH-HDTLNTAYTTLVGCILSVVLVLIYLYLTPCRCWCRGVEKPSSHQGDSLSSS 417 NFT+ H H+ NTA+TTL C+ S+VLVL+YLYLTPC C C+ + + + SS Sbjct: 384 NFTVSRSHAHEAFNTAFTTLAACVASIVLVLLYLYLTPCPCKCKTKRQKNMLHQSNAHSS 443 Query: 418 MLSTTPNHDPMAGGDKDDGFDRRVAFLEP-AGPGQGQNGKLK--PGNTLPVPEATGKGQR 474 +LS P D A ++ G +RV FLEP GQNGK++ P + + E K R Sbjct: 444 ILSPGPASDASA-DERKAGAGKRVVFLEPLKDTAAGQNGKVRLFPSEAV-IAEGILKSTR 501 Query: 475 RMSDPESVSSVFSDTPIV 492 SD +SV+SVFSDTP V Sbjct: 502 GKSDSDSVNSVFSDTPFV 519 >gi|38454322 adhesion molecule with Ig-like domain 3 [Homo sapiens] Length = 504 Score = 276 bits (706), Expect = 3e-74 Identities = 182/483 (37%), Positives = 249/483 (51%), Gaps = 29/483 (6%) Query: 29 RAVVSCPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQL 88 RA+ +CP C+CA+++LSC+ L +VP LP+ TA LDLSHN L RLR W L QL Sbjct: 29 RALHNCPYKCICAADLLSCTGLGLQDVPAELPAATADLDLSHNALQRLRPGWLAP-LFQL 87 Query: 89 HSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMA 148 +L L HN L+ + F LR LDLSSN LR L L LE LLL+NN ++ Sbjct: 88 RALHLDHNELDALGRGVFVNASGLRLLDLSSNTLRALGRHDLDGLGALEKLLLFNNRLVH 147 Query: 149 VDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDLQKL 208 +D AF + L LYL N+++ F + + G L LDLSSN+L ++ +P+L L Sbjct: 148 LDEHAFHGLRALSHLYLGCNELASFSFDHL-HGLSATHLLTLDLSSNRLGHISVPELAAL 206 Query: 209 PAWIKNGLYLHNNPLNCDCELYQLFSHWQYRQLSSVMDFQEDLYCMNSK---KLHNVFNL 265 PA++KNGLYLHNNPL CDC LY L W R LS+V DF + C+ K F Sbjct: 207 PAFLKNGLYLHNNPLPCDCRLYHLLQRWHQRGLSAVRDFAREYVCLAFKVPASRVRFFQH 266 Query: 266 S--FLNCG-------EYKERAWEAHLGDTLIIKCDTKQQGMTKVWVTPSNERV-LDEVTN 315 S F NC E E A +G +L + C+T M WV+P E + + Sbjct: 267 SRVFENCSSAPALGLERPEEHLYALVGRSLRLYCNTSVPAMRIAWVSPQQELLRAPGSRD 326 Query: 316 GTVSVSKDGSLLFQQVQVEDGGVYTCYAMGETFNETLSVELKVHNFTLHGHHDTLNTAYT 375 G+++V DGSL VQ + G++ C A G + + E V + NT +T Sbjct: 327 GSIAVLADGSLAIGNVQEQHAGLFVCLATGPRLHHNQTHEYNVSVHFPRPEPEAFNTGFT 386 Query: 376 TLVGCILSVVLVLIYLYLTPCRCWCRGV-------EKPSSHQGDSLSSSMLSTTPNHDPM 428 TL+GC + +VLVL+YL+ PCRC CR + PS Q S SS+LSTTP P Sbjct: 387 TLLGCAVGLVLVLLYLFAPPCRC-CRRACRCRRWPQTPSPLQELSAQSSVLSTTPPDAP- 444 Query: 429 AGGDKDDGFDRRVAFLEPAGPGQGQNGKLKPGNTLPVPEATGKGQRRMSDPESVSSVFSD 488 + + V FLEP +G NG+++ G + + ES SS+ S+ Sbjct: 445 ---SRKASVHKHVVFLEPG--RRGLNGRVQLAVAEEFDLYNPGGLQLKAGSESASSIGSE 499 Query: 489 TPI 491 P+ Sbjct: 500 GPM 502 >gi|31542244 leucine rich repeat and fibronectin type III domain containing 5 [Homo sapiens] Length = 719 Score = 105 bits (262), Expect = 9e-23 Identities = 106/384 (27%), Positives = 172/384 (44%), Gaps = 63/384 (16%) Query: 21 LFEVARAGRAVVSCPAACLCASNILS------CSKQQLPNVPHSLPSYTALLDLSHNNLS 74 LF + A +A + CP C+C ILS C+K+ L VP ++ T L L+ N ++ Sbjct: 8 LFLIGIAVKAQI-CPKRCVC--QILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVT 64 Query: 75 RLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQ 134 ++ + +T L L LS N ++FI+ AF+ + NLR L L+SN+L + +FS L Sbjct: 65 NIKRK-DFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLS 123 Query: 135 VLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKE-------------- 180 L L+L NN + + AFDD+ L++L LS N + P + V++ Sbjct: 124 NLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMI 183 Query: 181 -------GAKLPKLTLLDLSSNKLKNLPL-PDLQKLPAWIKNG--------LYLHNNPLN 224 + L K+T LD++SNKL+ LP P Q+ +G L NPL+ Sbjct: 184 DNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLH 243 Query: 225 CDCELYQLFSHWQYRQLSSVMDFQ--------EDLYCMNSKKLHNVFNLSFLNCGEYKER 276 C+CEL L R+LS D + Y + + + + ++ R Sbjct: 244 CNCELLWL------RRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMR 297 Query: 277 AWEAHLGDTLIIKCDTKQQGMTKV-WVTPSNERVLDEVTNGTVSVSKD-GSLLFQQVQVE 334 E G ++C + + W++P + ++N T S+ D G+L V+ Sbjct: 298 VLE---GQRATLRCKARGDPEPAIHWISPEGKL----ISNATRSLVYDNGTLDILITTVK 350 Query: 335 DGGVYTCYAMGETFNETLSVELKV 358 D G +TC A T V+L + Sbjct: 351 DTGAFTCIASNPAGEATQIVDLHI 374 >gi|126517478 peroxidasin homolog-like [Homo sapiens] Length = 1463 Score = 103 bits (257), Expect = 4e-22 Identities = 87/323 (26%), Positives = 148/323 (45%), Gaps = 52/323 (16%) Query: 34 CPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLL 93 CP+ CLC + + C L ++P +P T +LDL N + + +L L++LLL Sbjct: 24 CPSRCLCFKSTVRCMHLMLDHIPQ-VPQQTTVLDLRFNRIREIPGS-AFKKLKNLNTLLL 81 Query: 94 SHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCA 153 ++NH+ IS AF + NL YL L N++ LD+ F L LE L ++ N + + Sbjct: 82 NNNHIRKISRNAFEGLENLLYLYLYKNEIHALDKQTFKGLISLEHLYIHFNQLEMLQPET 141 Query: 154 FDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIK 213 F D+ +L++L+L N++S K+P + +L S K Sbjct: 142 FGDLLRLERLFLHNNKLS-----------KIPAGSFSNLDSLK----------------- 173 Query: 214 NGLYLHNNPLNCDC------ELYQLFSHWQYRQLSSVMDFQEDLYCMNSKKLHNVFNLSF 267 L L +N L CDC EL Q F+ + Q ++ ++ L+ + + +V + Sbjct: 174 -RLRLDSNALVCDCDLMWLGELLQGFAQHGHTQAAATCEYPRRLH---GRAVASV-TVEE 228 Query: 268 LNCGE----YKERAWEAHLGDTLIIKCDTKQQGMTK---VWVTPSNERVLDEVTNGTVSV 320 NC ++ + E G+T+ C + +G K +W+ N LD + ++V Sbjct: 229 FNCQSPRITFEPQDVEVPSGNTVYFTC--RAEGNPKPEIIWI--HNNHSLDLEDDTRLNV 284 Query: 321 SKDGSLLFQQVQVEDGGVYTCYA 343 DG+L+ + + D GVY C A Sbjct: 285 FDDGTLMIRNTRESDQGVYQCMA 307 >gi|109150416 peroxidasin [Homo sapiens] Length = 1479 Score = 100 bits (248), Expect = 4e-21 Identities = 92/341 (26%), Positives = 148/341 (43%), Gaps = 54/341 (15%) Query: 34 CPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLL 93 CP+ CLC + C L VP P T++LDL N + Sbjct: 36 CPSRCLCFRTTVRCMHLLLEAVPAVAPQ-TSILDLRFNRIRE------------------ 76 Query: 94 SHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCA 153 I AF + NL L L++NQ++ + F DL+ L+ L LY N I ++DR A Sbjct: 77 -------IQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQA 129 Query: 154 FDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIK 213 F +A L++LYL NQI + + LPKL L L +N++ +L L + + Sbjct: 130 FKGLASLEQLYLHFNQIETLDPDSFQH---LPKLERLFLHNNRITHLVPGTFNHLESMKR 186 Query: 214 NGLYLHNNPLNCDCELYQLFSHWQYRQLSSVMDFQEDLYCMNSKKLHN----VFNLSFLN 269 L L +N L+CDCE+ L + + + Q C +++ LN Sbjct: 187 --LRLDSNTLHCDCEILWLAD--LLKTYAESGNAQAAAICEYPRRIQGRSVATITPEELN 242 Query: 270 CGEYK----ERAWEAHLGDTLIIKCDTKQQGMTK---VWVTPSNERVLDEVTNGTVSVSK 322 C + + + G+T+ C + +G K +W+ +NE L T+ +++ Sbjct: 243 CERPRITSEPQDADVTSGNTVYFTC--RAEGNPKPEIIWLRNNNE--LSMKTDSRLNLLD 298 Query: 323 DGSLLFQQVQVEDGGVYTCYAMGETFNETLSVELKVHNFTL 363 DG+L+ Q Q D G+Y C A + ++ E+K TL Sbjct: 299 DGTLMIQNTQETDQGIYQCMA------KNVAGEVKTQEVTL 333 >gi|229089140 leucine rich repeat containing 24 [Homo sapiens] Length = 513 Score = 98.6 bits (244), Expect = 1e-20 Identities = 83/222 (37%), Positives = 108/222 (48%), Gaps = 16/222 (7%) Query: 13 LLPSLSLLLFEVARAGRAVVSCPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNN 72 LLP L LLL + AG CPAAC C S + C +L VP +P T L L NN Sbjct: 8 LLPLL-LLLLPLRAAG-----CPAACRCYSATVECGALRLRVVPLGIPPGTQTLFLQDNN 61 Query: 73 LSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSD 132 ++RL L L L L +N L + + AF P L L L+SN+LR L F Sbjct: 62 IARLEPG-ALAPLAALRRLYLHNNSLRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVG 120 Query: 133 LQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAK--LPKLTLL 190 L L VL L N + + F + +LQ+L+L +N I EL+++ A L L LL Sbjct: 121 LAQLRVLYLAGNQLARLLDFTFLHLPRLQELHLQENSI-----ELLEDQALAGLSSLALL 175 Query: 191 DLSSNKLKNLPLPDLQKLPAWIKNGLYLHNNPLNCDCELYQL 232 DLS N+L + LQ L + L L NP CDC L+ L Sbjct: 176 DLSRNQLGTISREALQPLASL--QVLRLTENPWRCDCALHWL 215 >gi|157694513 leucine-rich repeat-containing G protein-coupled receptor 4 [Homo sapiens] Length = 951 Score = 95.5 bits (236), Expect = 1e-19 Identities = 67/205 (32%), Positives = 104/205 (50%), Gaps = 7/205 (3%) Query: 20 LLFEVARAGRAVVSCPAACLC-ASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRA 78 LL +G A C A C C + CS + L VP L ++T LD+S NN+++L Sbjct: 15 LLGSAGPSGAAPPLCAAPCSCDGDRRVDCSGKGLTAVPEGLSAFTQALDISMNNITQL-P 73 Query: 79 EWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEV 138 E L L L+ N L+FI +A S + L+ L L +NQL+T+ L L+ Sbjct: 74 EDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQS 133 Query: 139 LLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLK 198 L L NHI +V +F+ + QL+ L+L N ++ P+ + + LP L L L+ NK+ Sbjct: 134 LRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPL---SNLPTLQALTLALNKIS 190 Query: 199 NLPLPDLQKLPAWIKNGLYLHNNPL 223 ++P L + + L+LHNN + Sbjct: 191 SIPDFAFTNLSSLVV--LHLHNNKI 213 Score = 67.8 bits (164), Expect = 2e-11 Identities = 54/184 (29%), Positives = 92/184 (50%), Gaps = 10/184 (5%) Query: 44 ILSCSKQQLPNVP-HSLPSYTAL--LDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNF 100 +L+ QL VP ++ +AL L L N+++ + E + L QL L L N L Sbjct: 109 VLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSV-PEDSFEGLVQLRHLWLDDNSLTE 167 Query: 101 ISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQL 160 + S +P L+ L L+ N++ ++ +F F++L L VL L+NN I ++ + FD + L Sbjct: 168 VPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNL 227 Query: 161 QKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIKNGLYLHN 220 + L L+ N + FP + LP L L SN + +P P + ++L++ Sbjct: 228 ETLDLNYNNLGEFPQAI----KALPSLKELGFHSNSISVIPDGAFDGNP--LLRTIHLYD 281 Query: 221 NPLN 224 NPL+ Sbjct: 282 NPLS 285 Score = 46.6 bits (109), Expect = 5e-05 Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 21/152 (13%) Query: 70 HNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFL 129 HNN R ++ L L +L L++N+L +A +P+L+ L SN + + + Sbjct: 209 HNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFP-QAIKALPSLKELGFHSNSISVIPDGA 267 Query: 130 FSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYL-SQNQISRFP-------LE-LVKE 180 F +L + LY+N + V AF +++ L L + + + +FP LE L Sbjct: 268 FDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLT 327 Query: 181 GAKLPK-----------LTLLDLSSNKLKNLP 201 G K+ L LDLS N +++LP Sbjct: 328 GTKISSIPNNLCQEQKMLRTLDLSYNNIRDLP 359 Score = 45.1 bits (105), Expect = 2e-04 Identities = 39/126 (30%), Positives = 54/126 (42%), Gaps = 5/126 (3%) Query: 83 TRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLY 142 T L SL L+ ++ I + LR LDLS N +R L F + LE + L Sbjct: 316 TGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSF--NGCHALEEISLQ 373 Query: 143 NNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPL 202 N I + F + L+ L LS+N I A L +T LD+S N+L + P Sbjct: 374 RNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAF---ATLGPITNLDVSFNELTSFPT 430 Query: 203 PDLQKL 208 L L Sbjct: 431 EGLNGL 436 >gi|11321571 slit homolog 3 [Homo sapiens] Length = 1523 Score = 95.1 bits (235), Expect = 1e-19 Identities = 82/260 (31%), Positives = 119/260 (45%), Gaps = 17/260 (6%) Query: 16 SLSLLLFEVARAGRAVVSCPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSR 75 +L+L L V +G V+CP C C++ + C L VP +P LDL NN++R Sbjct: 17 ALALALASVL-SGPPAVACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITR 75 Query: 76 LRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQV 135 + + L L L L N ++ I AF + L L L+ N+L+ L E LF Sbjct: 76 I-TKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPK 134 Query: 136 LEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGA--KLPKLTLLDLS 193 L L L N I + R AF + ++ L L N IS +++GA L L +L L+ Sbjct: 135 LTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHIS-----CIEDGAFRALRDLEILTLN 189 Query: 194 SNKLKNLPLPDLQKLPAWIKNGLYLHNNPLNCDCELYQLFSHWQYRQLSSVMDFQEDLYC 253 +N + + + +P L LH+N L CDC L L S W RQ +V F C Sbjct: 190 NNNISRILVTSFNHMPKI--RTLRLHSNHLYCDCHLAWL-SDW-LRQRRTVGQF---TLC 242 Query: 254 MNSKKLHNVFNLSFLNCGEY 273 M L FN++ + EY Sbjct: 243 MAPVHLRG-FNVADVQKKEY 261 Score = 82.0 bits (201), Expect = 1e-15 Identities = 59/212 (27%), Positives = 93/212 (43%), Gaps = 42/212 (19%) Query: 32 VSCPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSL 91 +SCP+ C C++NI+ C + L +P +LP + + Sbjct: 278 ISCPSPCTCSNNIVDCRGKGLMEIPANLPE-------------------------GIVEI 312 Query: 92 LLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDR 151 L N + I + AF+ L+ +D+S NQ+ + F L+ L L+LY N I + + Sbjct: 313 RLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAK 372 Query: 152 CAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNL------PLPDL 205 FD + LQ L L+ N+I+ + ++ L L LL L NKL+ + PL + Sbjct: 373 GLFDGLVSLQLLLLNANKINCLRVNTFQD---LQNLNLLSLYDNKLQTISKGLFAPLQSI 429 Query: 206 QKLPAWIKNGLYLHNNPLNCDCELYQLFSHWQ 237 Q L+L NP CDC L L + Q Sbjct: 430 QT--------LHLAQNPFVCDCHLKWLADYLQ 453 Score = 80.1 bits (196), Expect = 4e-15 Identities = 61/210 (29%), Positives = 95/210 (45%), Gaps = 29/210 (13%) Query: 34 CPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLL 93 CP C C I+ CS Q+L +P LP Y L L+ N +S L A +L L + L Sbjct: 505 CPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINL 564 Query: 94 SHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCA 153 S+N + + AF +++ L L+ NQL T+ +F L L+ L+L +N I V Sbjct: 565 SNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDT 624 Query: 154 FDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIK 213 F ++ ++ L L N+I+ + GA TL+ LS+ Sbjct: 625 FAGLSSVRLLSLYDNRIT-----TITPGA---FTTLVSLST------------------- 657 Query: 214 NGLYLHNNPLNCDCELYQLFSHWQYRQLSS 243 + L +NP NC+C L L + R++ S Sbjct: 658 --INLLSNPFNCNCHLAWLGKWLRKRRIVS 685 Score = 74.7 bits (182), Expect = 2e-13 Identities = 50/157 (31%), Positives = 79/157 (50%), Gaps = 7/157 (4%) Query: 34 CPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLL 93 CP C C ++ CS + L +P +P L L N+L+ + E + R L + L Sbjct: 725 CPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRELSALR--HLTLIDL 782 Query: 94 SHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCA 153 S+N ++ +++ FS + +L L LS N+LR + F+ L+ L VL L+ N I +V + Sbjct: 783 SNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGS 842 Query: 154 FDDMAQLQKLYLSQNQIS-----RFPLELVKEGAKLP 185 F+D+ L L L N + R+ E VK G K P Sbjct: 843 FNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEP 879 >gi|153791330 leucine rich repeat neuronal 1 [Homo sapiens] Length = 716 Score = 93.2 bits (230), Expect = 5e-19 Identities = 80/297 (26%), Positives = 133/297 (44%), Gaps = 27/297 (9%) Query: 85 LTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYN- 143 L L SL N L + A VPNL++LDL+ N + + E F ++ L+ L + N Sbjct: 238 LDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNM 297 Query: 144 NHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLP 203 +++VDR A D++ +L KL + N + L +P L L L++N L + Sbjct: 298 GELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRS--VPALESLMLNNNALNAIYQK 355 Query: 204 DLQKLPAWIKNGLYLHNNPLNCDCELYQLFSHWQYRQLSSVMDFQEDL--YCMNSK--KL 259 ++ LP + + +H+NPL CDC + HW +++ F E L +C K Sbjct: 356 TVESLPNLRE--ISIHSNPLRCDCVI-----HWINSNKTNIR-FMEPLSMFCAMPPEYKG 407 Query: 260 HNVFNLSFLNCGE----------YKERAWEAHLGDTLIIKCDTKQQGMTKV-WVTPSNER 308 H V + + E + R +G T+ + C + ++ WVTP + Sbjct: 408 HQVKEVLIQDSSEQCLPMISHDSFPNRL-NVDIGTTVFLDCRAMAEPEPEIYWVTPIGNK 466 Query: 309 VLDEVTNGTVSVSKDGSLLFQQVQVEDGGVYTCYAMGETFNETLSVELKVHNFTLHG 365 + E + +S +G+L +Q+ED G YTC A +T +KV+ L G Sbjct: 467 ITVETLSDKYKLSSEGTLEISNIQIEDSGRYTCVAQNVQGADTRVATIKVNGTLLDG 523 Score = 66.2 bits (160), Expect = 6e-11 Identities = 64/267 (23%), Positives = 107/267 (40%), Gaps = 64/267 (23%) Query: 17 LSLLLFEVARAGRAVVSCPAACLCA-------------SNILSCSKQQLPNVPHSLPSYT 63 L LL+ + + CP C+C + + C+ +L +P +L S T Sbjct: 15 LGLLMTSLTESSIQNSECPQLCVCEIRPWFTPQSTYREATTVDCNDLRLTRIPSNLSSDT 74 Query: 64 ALLDLSHNNLSRLRAEWTP-------------------------TRLTQLH--------- 89 +L L NN+++ E T+LT LH Sbjct: 75 QVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEM 134 Query: 90 ------------SLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLE 137 L ++HN ++ IS+ AF+ + NL L L+SN+L+ +D F LE Sbjct: 135 TDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLE 194 Query: 138 VLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKL 197 +L++ N ++ + F +A L+ L L+ ++ P + L L L NKL Sbjct: 195 ILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNAL---VGLDSLESLSFYDNKL 251 Query: 198 KNLPLPDLQKLPAWIKNGLYLHNNPLN 224 +P LQK+P L L+ NP++ Sbjct: 252 VKVPQLALQKVPN--LKFLDLNKNPIH 276 >gi|122937309 leucine rich repeat containing 4B [Homo sapiens] Length = 713 Score = 92.8 bits (229), Expect = 6e-19 Identities = 115/444 (25%), Positives = 173/444 (38%), Gaps = 98/444 (22%) Query: 3 PHRDPRGLWLLLPSLSLLLFEVARAGRA------VVSCPAACLCASNI--LSCSKQQLPN 54 PH LWL P L VA A SCP AC C++ + C+++ L Sbjct: 20 PHGALLFLWLFSPPLGAGGGGVAVTSAAGGGSPPATSCPVACSCSNQASRVICTRRDLAE 79 Query: 55 VPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRY 114 VP S+P T L+L N + +R + T L L L LS N + I AF+ +P+L Sbjct: 80 VPASIPVNTRYLNLQENGIQVIRTD-TFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNT 138 Query: 115 LDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFD--------DMAQLQKL-YL 165 L+L N+L T+ F L L L L NN I ++ AF+ D+ +L++L Y+ Sbjct: 139 LELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYI 198 Query: 166 SQN---------------------------------QISRFPLELVKEGA-----KLPKL 187 S+ ++S L+L++ G+ L KL Sbjct: 199 SEAAFEGLVNLRYLNLGMCNLKDIPNLTALVRLEELELSGNRLDLIRPGSFQGLTSLRKL 258 Query: 188 TLL-------------DLSSNKLKNLPLPDLQKLPAWIKNGLY------LHNNPLNCDCE 228 L+ DL S + NL +L LP + L+ L++NP +C+C+ Sbjct: 259 WLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCNCD 318 Query: 229 LYQLFSHWQYRQLSSVMDFQEDLYCMNSKKLHNVFNLSFLNCGEYKERAWEAHL------ 282 + L S W + S + C + H L GE + + + Sbjct: 319 VLWL-SWWLKETVPS------NTTCC--ARCHAPAGLKGRYIGELDQSHFTCYAPVIVEP 369 Query: 283 --------GDTLIIKCDTKQQGMTKVWVTPSNERVLDEVTNGTVSVSKDGSLLFQQVQVE 334 G +KC T + W+TP+ + +SV DG+L F V V+ Sbjct: 370 PTDLNVTEGMAAELKCRTGTSMTSVNWLTPNGTLMTHGSYRVRISVLHDGTLNFTNVTVQ 429 Query: 335 DGGVYTCYAMGETFNETLSVELKV 358 D G YTC N T S L V Sbjct: 430 DTGQYTCMVTNSAGNTTASATLNV 453 >gi|4759146 slit homolog 2 [Homo sapiens] Length = 1529 Score = 89.4 bits (220), Expect = 7e-18 Identities = 61/200 (30%), Positives = 92/200 (46%), Gaps = 30/200 (15%) Query: 30 AVVSCPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLH 89 +V+ CPAAC C++NI+ C + L +P +LP + Sbjct: 269 SVLHCPAACTCSNNIVDCRGKGLTEIPTNLPE-------------------------TIT 303 Query: 90 SLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAV 149 + L N + I AFSP LR +DLS+NQ+ L F L+ L L+LY N I + Sbjct: 304 EIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITEL 363 Query: 150 DRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDLQKLP 209 + F+ + LQ L L+ N+I+ ++ ++ L L LL L NKL+ + L Sbjct: 364 PKSLFEGLFSLQLLLLNANKINCLRVDAFQD---LHNLNLLSLYDNKLQTIAKGTFSPLR 420 Query: 210 AWIKNGLYLHNNPLNCDCEL 229 A ++L NP CDC L Sbjct: 421 A--IQTMHLAQNPFICDCHL 438 Score = 87.8 bits (216), Expect = 2e-17 Identities = 81/278 (29%), Positives = 119/278 (42%), Gaps = 55/278 (19%) Query: 8 RGLWLLLPSLSLLLFEVARAGRAVVSCPAACLCASNILSCSKQQLPNVPHSLPSYTALLD 67 RG+ + SLSL L A +CPA C C+ + + C L +VP ++P T LD Sbjct: 2 RGVGWQMLSLSLGLVLAILNKVAPQACPAQCSCSGSTVDCHGLALRSVPRNIPRNTERLD 61 Query: 68 LSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDE 127 L+ NN++R I+ F+ + +LR L L N++ T++ Sbjct: 62 LNGNNITR-------------------------ITKTDFAGLRHLRVLQLMENKISTIER 96 Query: 128 FLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFP------------- 174 F DL+ LE L L NH+ F A+L +L LS+NQI P Sbjct: 97 GAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNL 156 Query: 175 ------LELVKEGA--KLPKLTLLDLSSNKLKNLPLPDLQKLPAWIKNGLYLHNNPLNCD 226 + +++GA L L +L L++N + L + +P LH+N L CD Sbjct: 157 QLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPK--LRTFRLHSNNLYCD 214 Query: 227 CELYQLFSHWQYRQLSSVMDFQEDLYCMNSKKL--HNV 262 C L L S W RQ V + + CM L HNV Sbjct: 215 CHLAWL-SDW-LRQRPRVGLYTQ---CMGPSHLRGHNV 247 Score = 82.4 bits (202), Expect = 9e-16 Identities = 53/168 (31%), Positives = 85/168 (50%), Gaps = 7/168 (4%) Query: 30 AVVSCPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLH 89 A ++CP C C + CS Q+L +P +P YTA L L++N + L A +L QL Sbjct: 502 ADLACPEKCRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLR 561 Query: 90 SLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAV 149 + S+N + I AF + + L+SN+L + +F L+ L+ L+L +N I V Sbjct: 562 KINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCV 621 Query: 150 DRCAFDDMAQLQKLYLSQNQISRFPLELVKEGA--KLPKLTLLDLSSN 195 +F ++ ++ L L NQI+ V GA L L+ L+L +N Sbjct: 622 GNDSFIGLSSVRLLSLYDNQIT-----TVAPGAFDTLHSLSTLNLLAN 664 Score = 66.6 bits (161), Expect = 5e-11 Identities = 41/137 (29%), Positives = 69/137 (50%), Gaps = 2/137 (1%) Query: 34 CPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLL 93 CP C C ++ CS + L +P +P L L N + + E + + L + L Sbjct: 727 CPTECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKELSNYK--HLTLIDL 784 Query: 94 SHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCA 153 S+N ++ +S+++FS + L L LS N+LR + F L+ L +L L+ N I V A Sbjct: 785 SNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGA 844 Query: 154 FDDMAQLQKLYLSQNQI 170 F+D++ L L + N + Sbjct: 845 FNDLSALSHLAIGANPL 861 >gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens] Length = 2623 Score = 89.4 bits (220), Expect = 7e-18 Identities = 72/235 (30%), Positives = 119/235 (50%), Gaps = 13/235 (5%) Query: 8 RGLWLLLPSLSLLLFEVARAGRAVVSCPAACLC-ASNILSCSKQQLPNVPHSLPSYTALL 66 RG+ LL S +++ G+A CP C C + C+ + L ++P S+P + Sbjct: 6 RGITCLLVSFAVICLVATPGGKA---CPRRCACYMPTEVHCTFRYLTSIPDSIPPNVERI 62 Query: 67 DLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLD 126 +L +N+L RL E + LT+L L+L N ++ I + FS + L+ L +S N++R L Sbjct: 63 NLGYNSLVRLM-ETDFSGLTKLELLMLHSNGIHTIPDKTFSDLQALQVLKMSYNKVRKLQ 121 Query: 127 EFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRF-PLELVK----EG 181 + F L+ L L + +N+I ++ F + L+ ++L NQ+++ P V + Sbjct: 122 KDTFYGLRSLTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGNQLTKLHPDTFVSLSYLQI 181 Query: 182 AKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIKNGLYLHNNPLNCDCELYQLFSHW 236 K+ + L LS N L +LP + +P + LYLH NP CDC L L S W Sbjct: 182 FKISFIKFLYLSDNFLTSLPQEMVSYMPD--LDSLYLHGNPWTCDCHLKWL-SDW 233 Score = 39.7 bits (91), Expect = 0.006 Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 3/77 (3%) Query: 283 GDTLIIKCDTKQQGMTKV-WVTPSNERVLDEVTNGTVSVSKDGSLLFQQVQVEDGGVYTC 341 GDT ++ C+ K+ W+ PSN+ + + T + GSL +V++ D G Y C Sbjct: 2156 GDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHAN--GSLTINKVKLLDSGEYVC 2213 Query: 342 YAMGETFNETLSVELKV 358 A + ++T +L V Sbjct: 2214 VARNPSGDDTKMYKLDV 2230 Score = 39.3 bits (90), Expect = 0.008 Identities = 24/90 (26%), Positives = 46/90 (51%), Gaps = 4/90 (4%) Query: 272 EYKERAWEAHLGDTLIIKCDTK-QQGMTKVWVTPSNERVLDEVTNGT--VSVSKDGSLLF 328 E + + H G T+ +KC + + T W+ +N+ V+ E + G+ V+ DG+L+ Sbjct: 1749 ERRTKEITVHSGSTVELKCRAEGRPSPTVTWIL-ANQTVVSESSQGSRQAVVTVDGTLVL 1807 Query: 329 QQVQVEDGGVYTCYAMGETFNETLSVELKV 358 + + D G Y C A ++L V+++V Sbjct: 1808 HNLSIYDRGFYKCVASNPGGQDSLLVKIQV 1837 Score = 35.0 bits (79), Expect = 0.16 Identities = 21/86 (24%), Positives = 41/86 (47%), Gaps = 2/86 (2%) Query: 275 ERAWEAHLGDTLIIKCDTKQQGMTKV-WVTPSNERVLDEVTNGT-VSVSKDGSLLFQQVQ 332 ++ E + GD L++ C + ++ W PS V + G+ + V +GSL V Sbjct: 1948 QKRTEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVT 2007 Query: 333 VEDGGVYTCYAMGETFNETLSVELKV 358 +D GVY C A + ++ + + + + Sbjct: 2008 EKDSGVYLCVARNKMGDDLILMHVSL 2033 Score = 33.5 bits (75), Expect = 0.45 Identities = 16/59 (27%), Positives = 29/59 (49%) Query: 300 VWVTPSNERVLDEVTNGTVSVSKDGSLLFQQVQVEDGGVYTCYAMGETFNETLSVELKV 358 +W+ P N + ++V K+G+L + V++ D + C A E L V+L+V Sbjct: 2272 MWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEV 2330 Score = 31.2 bits (69), Expect = 2.3 Identities = 18/58 (31%), Positives = 28/58 (48%) Query: 304 PSNERVLDEVTNGTVSVSKDGSLLFQQVQVEDGGVYTCYAMGETFNETLSVELKVHNF 361 PS + N V V +G+L Q+V+++D G Y C A + L V L V ++ Sbjct: 1686 PSGLDLSKRKQNSRVQVLPNGTLSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVVSY 1743 Score = 30.4 bits (67), Expect = 3.8 Identities = 14/36 (38%), Positives = 20/36 (55%) Query: 323 DGSLLFQQVQVEDGGVYTCYAMGETFNETLSVELKV 358 +G+L F +V V + G YTCYA + + V L V Sbjct: 2101 NGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTV 2136 Score = 30.4 bits (67), Expect = 3.8 Identities = 47/212 (22%), Positives = 82/212 (38%), Gaps = 23/212 (10%) Query: 157 MAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWI-KNG 215 + QL+ L + + R P K A+L K T L+ S + P P++ WI NG Sbjct: 2325 VVQLEVLEMLRRPTFRNPFN-EKIVAQLGKSTALNCS---VDGNPPPEI----IWILPNG 2376 Query: 216 LYLHNNPLNCDCELYQLFSHWQYRQLSSVMDFQEDLYCMNSKKLHNVFNLSFLNCGE--- 272 N P + Y + S+ + + + C K+ + L L G+ Sbjct: 2377 TRFSNGPQSYQ---YLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPV 2433 Query: 273 ---YKERAWEAHLGDTLIIKCDTKQQGMTKV---WVTPSNERVLDEVTNGTVSVSKDGSL 326 Y + G++L + C + G+ K W PS V NG + +G+L Sbjct: 2434 ILTYAPGTVKGISGESLSLHCVS--DGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTL 2491 Query: 327 LFQQVQVEDGGVYTCYAMGETFNETLSVELKV 358 + ++ D G Y C A + ++V + + Sbjct: 2492 VIKEATAYDRGNYICKAQNSVGHTLITVPVMI 2523 Score = 30.0 bits (66), Expect = 5.0 Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 2/76 (2%) Query: 283 GDTLIIKCDTKQQGMTKV-WVTPSNERVLD-EVTNGTVSVSKDGSLLFQQVQVEDGGVYT 340 G++L + C K V WV V + TN + + +G+L + + D G Y Sbjct: 1857 GESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYE 1916 Query: 341 CYAMGETFNETLSVEL 356 C A T +E V L Sbjct: 1917 CIATSSTGSERRVVML 1932 >gi|62912470 leucine-rich repeat-containing G protein-coupled receptor 6 isoform 1 [Homo sapiens] Length = 967 Score = 89.0 bits (219), Expect = 9e-18 Identities = 66/198 (33%), Positives = 100/198 (50%), Gaps = 10/198 (5%) Query: 28 GRAVVSCPAACLCASNIL----SCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPT 83 G +CPA C C + + CS+ L VP L TA LDLS NNL+ L+ Sbjct: 29 GPGPTACPAPCHCQEDGIMLSADCSELGLSAVPGDLDPLTAYLDLSMNNLTELQPGLFH- 87 Query: 84 RLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYN 143 L L L LS NHL+ I +AFS + +L+ L L +NQL + +L L+ L L Sbjct: 88 HLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDA 147 Query: 144 NHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLP 203 N I V +F+ ++ L+ L+L N ++ P+ + LP L + L+ N++ ++P Sbjct: 148 NLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALN---NLPALQAMTLALNRISHIPDY 204 Query: 204 DLQKLPAWIKNGLYLHNN 221 Q L + + L+LHNN Sbjct: 205 AFQNLTSLVV--LHLHNN 220 Score = 62.4 bits (150), Expect = 9e-10 Identities = 59/217 (27%), Positives = 98/217 (45%), Gaps = 15/217 (6%) Query: 39 LCASNILSCSKQQLPNVPHS----LPSYTAL-LDLSHNNLSRLRAEWTPTRLTQLHSLLL 93 L + IL QL +P LPS +L LD NL L E + L+ L L L Sbjct: 113 LYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDA---NLISLVPERSFEGLSSLRHLWL 169 Query: 94 SHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCA 153 N L I A + +P L+ + L+ N++ + ++ F +L L VL L+NN I + + Sbjct: 170 DDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHS 229 Query: 154 FDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIK 213 F+ + L+ L L+ N++ FP+ + L +L L +N +K +P P + Sbjct: 230 FEGLHNLETLDLNYNKLQEFPVAI----RTLGRLQELGFHNNNIKAIPEKAFMGNP--LL 283 Query: 214 NGLYLHNNPLN-CDCELYQLFSHWQYRQLSSVMDFQE 249 ++ ++NP+ +Q L+ MD QE Sbjct: 284 QTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQE 320 Score = 50.1 bits (118), Expect = 5e-06 Identities = 40/120 (33%), Positives = 54/120 (45%), Gaps = 5/120 (4%) Query: 86 TQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNH 145 T L L L+ + + S +P LR L+LS NQ+ L Q LE + L +N Sbjct: 328 TSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNR 385 Query: 146 IMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDL 205 I + F ++ LQ L LS N I E + L L LDL+ N+L LPL L Sbjct: 386 IWEIGADTFSQLSSLQALDLSWNAIRSIHPEAF---STLHSLVKLDLTDNQLTTLPLAGL 442 Score = 44.7 bits (104), Expect = 2e-04 Identities = 37/121 (30%), Positives = 58/121 (47%), Gaps = 14/121 (11%) Query: 50 QQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPV 109 QQLP + +L+LSHN + L + R +L + L HN + I ++ FS + Sbjct: 349 QQLPRL--------RVLELSHNQIEELPSLH---RCQKLEEIGLQHNRIWEIGADTFSQL 397 Query: 110 PNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQ---KLYLS 166 +L+ LDLS N +R++ FS L L L L +N + + + L+ L LS Sbjct: 398 SSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALS 457 Query: 167 Q 167 Q Sbjct: 458 Q 458 >gi|52138725 leucine rich repeat and Ig domain containing 4 [Homo sapiens] Length = 593 Score = 88.2 bits (217), Expect = 2e-17 Identities = 76/210 (36%), Positives = 102/210 (48%), Gaps = 13/210 (6%) Query: 7 PRGLWLLLPSLSLLLFEVARAGRAVVSCPAACLCASN--ILSCSKQQLPNVPHSLPSYTA 64 P+ W P LLF + G + SCPA C C S + C +QL VP LP T Sbjct: 7 PKQAW---PPWPPLLFLLLLPGGSGGSCPAVCDCTSQPQAVLCGHRQLEAVPGGLPLDTE 63 Query: 65 LLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRT 124 LLDLS N L L+ + +RL+ L L LS+N L+ + AF + +L L L N+LR Sbjct: 64 LLDLSGNRLWGLQ-QGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRI 122 Query: 125 LDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEG--A 182 + +FS L L +L L N I+ AF ++ LQKL + N L V G A Sbjct: 123 MGPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNH-----LVFVAPGAFA 177 Query: 183 KLPKLTLLDLSSNKLKNLPLPDLQKLPAWI 212 L KL+ L L L +P L +LPA + Sbjct: 178 GLAKLSTLTLERCNLSTVPGLALARLPALV 207 Score = 52.8 bits (125), Expect = 7e-07 Identities = 98/423 (23%), Positives = 156/423 (36%), Gaps = 88/423 (20%) Query: 85 LTQLHSLLLSHNHLNFISSEAFSPVP-----NLRYLDLSS---------NQLRTLDEFLF 130 L +L +L L +L+ + A + +P LR LD+ QL+ L+ L+ Sbjct: 179 LAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGLGQLKELEIHLW 238 Query: 131 SDLQVLEV--LLLYNNHIMAVDRC--------AFDDMAQLQKLYLSQNQISRFPL----- 175 L+ L+ L+ N +A+ RC A ++ L+ L LSQN IS P Sbjct: 239 PSLEALDPGSLVGLNLSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSP 298 Query: 176 -----ELVKEGAKLPKLT-----------LLDLSSNKLKNLP---LPDLQKLPAWIKNGL 216 EL GA L + LLD++ N L+ L P KL L Sbjct: 299 LVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVT-----L 353 Query: 217 YLHNNPLNCDCE---LYQLFSHWQYRQLSSVMDFQEDLYCMNSKKLHNVFNLSFLNCGEY 273 L NPL CDC L +L H + + + K+ ++ C Sbjct: 354 RLSGNPLTCDCRLLWLLRLRRHLDFGMSPPACAGPHHVQGKSLKEFSDILPPGHFTCKPA 413 Query: 274 KER----AWE-AHLGDTLIIKCD-TKQQGMTKVWVTPSNERVLDEVTNGTVSVSKDGSLL 327 R W A G + C T W+ P + G V V +DG+L Sbjct: 414 LIRKSGPRWVIAEEGGHAVFSCSGDGDPAPTVSWMRPHGAWL---GRAGRVRVLEDGTLE 470 Query: 328 FQQVQVEDGGVYTCYAMGETFNETLSVELKVHNFTLHGHHDTLNTAYTTL---------- 377 + VQ+ D G Y C N++L L+V + + TL+ T+ Sbjct: 471 IRSVQLRDRGAYVCVVSNVAGNDSLRTWLEV--IQVEPPNGTLSDPNITVPGIPGPFFLD 528 Query: 378 ---VGCILSVVLVLIYLYLTPC----RCWCRGVEKPSSHQGDSLSSSMLSTTPNHDPMAG 430 V +L+V + +T C W +G + H ++ ++ P+ D +G Sbjct: 529 SRGVAMVLAVGFLPFLTSVTLCFGLIALWSKGKGRVKHH----MTFDFVAPRPSGDKNSG 584 Query: 431 GDK 433 G++ Sbjct: 585 GNR 587 Score = 40.0 bits (92), Expect = 0.005 Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Query: 44 ILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISS 103 I C+ +P S+ +LDLS N +S + A + L +L L LS L I++ Sbjct: 259 ITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRL-SPLVRLQELRLSGACLTSIAA 317 Query: 104 EAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNN 144 AF + LD++ N L+TL+E F L L L N Sbjct: 318 HAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGN 358 >gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3 isoform 2 [Homo sapiens] Length = 1119 Score = 87.8 bits (216), Expect = 2e-17 Identities = 64/191 (33%), Positives = 100/191 (52%), Gaps = 31/191 (16%) Query: 34 CPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLL 93 CP C C ++L CS+++L +P LPS+ A LDLSHN LS ++A + + L L + L Sbjct: 47 CPTTCRCLGDLLDCSRKRLARLPEPLPSWVARLDLSHNRLSFIKAS-SMSHLQSLREVKL 105 Query: 94 SHNHLNFISS-----------------------EAFSPVPNLRYLDLSSNQLRTLDEFLF 130 ++N L I + E +L LDLSSN + L + F Sbjct: 106 NNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISEL-QTAF 164 Query: 131 SDLQVLEVLLLYNNHIMAVDRCAFDDMAQ-LQKLYLSQNQISRFPLELVKEGAKLPKLTL 189 LQ L+ L L +N + +++ FD++A L L L++N+IS P ++ KLP+L Sbjct: 165 PALQ-LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMF----KLPQLQH 219 Query: 190 LDLSSNKLKNL 200 L+L+ NK+KN+ Sbjct: 220 LELNRNKIKNV 230 Score = 70.9 bits (172), Expect = 3e-12 Identities = 59/193 (30%), Positives = 90/193 (46%), Gaps = 35/193 (18%) Query: 65 LLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRT 124 +L L HNNL+ + W L L L LS N +N IS +A+ L LDL+ N L Sbjct: 267 ILQLDHNNLTEITKGWL-YGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSR 325 Query: 125 LDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLE-------- 176 LD+ F L +L L + NN + + CAF ++ L+ L L N+IS + +E Sbjct: 326 LDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEIS-WTIEDMNGAFSG 384 Query: 177 ------LVKEGAKLPKLTL-----------LDLSSNKLKNLP---LPDLQKLPAWIKNGL 216 L+ +G ++ +T LDLS N + +L ++KL L Sbjct: 385 LDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQ-----L 439 Query: 217 YLHNNPLNCDCEL 229 +L+ + L CDC+L Sbjct: 440 HLNTSSLLCDCQL 452 Score = 51.6 bits (122), Expect = 2e-06 Identities = 50/184 (27%), Positives = 86/184 (46%), Gaps = 9/184 (4%) Query: 53 PNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNL 112 P +L + +L L+ N +S + + +L QL L L+ N + + F + L Sbjct: 184 PGYFDNLANTLLVLKLNRNRISAIPPKMF--KLPQLQHLELNRNKIKNVDGLTFQGLGAL 241 Query: 113 RYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISR 172 + L + N + L + F L +E+L L +N++ + + + LQ+L+LSQN I+R Sbjct: 242 KSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINR 301 Query: 173 FPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIKNGLYLHNNPLN--CDCELY 230 + + KL+ LDL+ N L L D L + N L++ NN ++ DC Sbjct: 302 ISPDAWE---FCQKLSELDLTFNHLSR--LDDSSFLGLSLLNTLHIGNNRVSYIADCAFR 356 Query: 231 QLFS 234 L S Sbjct: 357 GLSS 360 >gi|188528675 slit homolog 1 [Homo sapiens] Length = 1534 Score = 87.0 bits (214), Expect = 3e-17 Identities = 61/194 (31%), Positives = 95/194 (48%), Gaps = 11/194 (5%) Query: 32 VSCPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSL 91 V CP C C +N++ CS +L +P +P TA L L++N +S L A +LT L + Sbjct: 511 VVCPHKCRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKI 570 Query: 92 LLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDR 151 LS+N ++ I AF ++ L L++NQL ++ +F L L L+L NN I + Sbjct: 571 NLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHN 630 Query: 152 CAFDDMAQLQKLYLSQNQISRFPLELVKEGA--KLPKLTLLDLSSNKLK-NLPLPDLQKL 208 +F + ++ L L NQI+ V GA L L+ L+L +N N L L Sbjct: 631 DSFTGLRNVRLLSLYDNQIT-----TVSPGAFDTLQSLSTLNLLANPFNCNC---QLAWL 682 Query: 209 PAWIKNGLYLHNNP 222 W++ + NP Sbjct: 683 GGWLRKRKIVTGNP 696 Score = 80.9 bits (198), Expect = 2e-15 Identities = 61/197 (30%), Positives = 90/197 (45%), Gaps = 30/197 (15%) Query: 33 SCPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLL 92 SCPA C C++ I+ C + L +P +LP ++ +R E Sbjct: 281 SCPAMCTCSNGIVDCRGKGLTAIPANLPE----------TMTEIRLEL------------ 318 Query: 93 LSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRC 152 N + I AFSP LR +DLS+NQ+ + F L+ L L+LY N I + R Sbjct: 319 ---NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRG 375 Query: 153 AFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWI 212 F + LQ L L+ N+I+ + ++ L L+LL L NK+++L L A Sbjct: 376 VFGGLYTLQLLLLNANKINCIRPDAFQD---LQNLSLLSLYDNKIQSLAKGTFTSLRA-- 430 Query: 213 KNGLYLHNNPLNCDCEL 229 L+L NP CDC L Sbjct: 431 IQTLHLAQNPFICDCNL 447 Score = 79.7 bits (195), Expect = 6e-15 Identities = 68/244 (27%), Positives = 103/244 (42%), Gaps = 52/244 (21%) Query: 15 PSLSLLLFEVA-RAGRAVVSCPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNL 73 P L LLL+ A R G + +CPA C C + C L +P ++P T L+L+ NN+ Sbjct: 16 PELWLLLWAAAWRLGAS--ACPALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNI 73 Query: 74 SRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDL 133 +R+ H N F+ + LR L L NQ+ ++ F D+ Sbjct: 74 TRI--------------------HKN-----DFAGLKQLRVLQLMENQIGAVERGAFDDM 108 Query: 134 QVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFP------------------- 174 + LE L L N + + F + L +L LS+N I P Sbjct: 109 KELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQ 168 Query: 175 LELVKEGA--KLPKLTLLDLSSNKLKNLPLPDLQKLPAWIKNGLYLHNNPLNCDCELYQL 232 + ++EGA L L +L L++N + +P+ +P LH+N L CDC L L Sbjct: 169 ISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPK--LRTFRLHSNHLFCDCHLAWL 226 Query: 233 FSHW 236 S W Sbjct: 227 -SQW 229 Score = 62.4 bits (150), Expect = 9e-10 Identities = 41/134 (30%), Positives = 63/134 (47%), Gaps = 24/134 (17%) Query: 34 CPAACLCASNILSCSKQQLPNVPHSLPS-----------------------YTALLDLSH 70 CP C C ++ CS + L +P +P Y L+DLS+ Sbjct: 734 CPQECACLDTVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDLSN 793 Query: 71 NNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLF 130 N +S L + + T ++QL +L+LS+N L I AF + +LR L L N + TL E +F Sbjct: 794 NKISSL-SNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIF 852 Query: 131 SDLQVLEVLLLYNN 144 +D+ L L + N Sbjct: 853 ADVTSLSHLAIGAN 866 >gi|15029530 leucine rich repeat containing 4 [Homo sapiens] Length = 653 Score = 86.7 bits (213), Expect = 5e-17 Identities = 108/447 (24%), Positives = 171/447 (38%), Gaps = 97/447 (21%) Query: 10 LWLLLPSLSLLLFEVARAGRAVVSCPAACLCASNI--LSCSKQQLPNVPHSLPSYTALLD 67 +W+L +++ A A +CP+ C C++ + C+++ L VP +PS T L+ Sbjct: 28 VWILCAAIA------AAASAGPQNCPSVCSCSNQFSKVVCTRRGLSEVPQGIPSNTRYLN 81 Query: 68 L-----------------------------------SHNNLSRLRA-----EWTPT---- 83 L + N L+ L W Sbjct: 82 LMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSG 141 Query: 84 ---RLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSS-NQLRTLDEFLF--------- 130 L++L L L +N + I S AF+ VP+L LDL +L + E F Sbjct: 142 AFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYL 201 Query: 131 -------------SDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLEL 177 + L LE L + NH + +F ++ L+KL++ +Q+S L Sbjct: 202 NLGMCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVS-----L 256 Query: 178 VKEGA--KLPKLTLLDLSSNKLKNLPLPDLQKLPAWIKNGLYLHNNPLNCDCELYQLFSH 235 ++ A L L L+L+ N L +LP L ++ L+LH+NP NCDC++ L+ Sbjct: 257 IERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVE--LHLHHNPWNCDCDI--LWLA 312 Query: 236 WQYRQL----SSVMDFQEDLYCMNSKKLHNVFNLSFLNCGEY---KERAWEAHLGDTLII 288 W R+ S+ M + L V SF + R G + Sbjct: 313 WWLREYIPTNSTCCGRCHAPMHMRGRYLVEVDQASFQCSAPFIMDAPRDLNISEGRMAEL 372 Query: 289 KCDTKQQGMTKVWVTPSNERVLDEVTNGTVSVSKDGSLLFQQVQVEDGGVYTCYAMGETF 348 KC T K W+ P+ + + +SV DG+L F V + D GVYTC Sbjct: 373 KCRTPPMSSVK-WLLPNGTVLSHASRHPRISVLNDGTLNFSHVLLSDTGVYTCMVTNVAG 431 Query: 349 NETLSVELKVHNFTLHGHHDTLNTAYT 375 N S L V L+ + + T T Sbjct: 432 NSNASAYLNVSTAELNTSNYSFFTTVT 458 >gi|4504379 leucine-rich repeat-containing G protein-coupled receptor 5 [Homo sapiens] Length = 907 Score = 86.3 bits (212), Expect = 6e-17 Identities = 69/223 (30%), Positives = 110/223 (49%), Gaps = 13/223 (5%) Query: 9 GLWLLLPSLSLLLF--EVARAGRAVVSCPAACLCASN-----ILSCSKQQLPNVPHSLPS 61 G+ L LP L L R+G + CP C C + + CS L +P +L Sbjct: 7 GVLLSLPVLLQLATGGSSPRSGVLLRGCPTHCHCEPDGRMLLRVDCSDLGLSELPSNLSV 66 Query: 62 YTALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQ 121 +T+ LDLS NN+S+L P+ L L L L+ N L +I AF+ + +L+ L L +NQ Sbjct: 67 FTSYLDLSMNNISQLLPNPLPS-LRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQ 125 Query: 122 LRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEG 181 LR + +L+ L+ L L NHI V F + L+ L+L N ++ P++ + Sbjct: 126 LRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFR-- 183 Query: 182 AKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIKNGLYLHNNPLN 224 L L + L+ NK+ ++P L + + L+LHNN ++ Sbjct: 184 -SLSALQAMTLALNKIHHIPDYAFGNLSSLVV--LHLHNNRIH 223 Score = 66.6 bits (161), Expect = 5e-11 Identities = 63/219 (28%), Positives = 106/219 (48%), Gaps = 20/219 (9%) Query: 14 LPSLSLLLFEVARAGRAVVSCPAAC---LCASNILSCSKQQLPNVP-HSLPSYTAL--LD 67 LPSL L E+ AG A+ P L + +L QL +VP +L + +L L Sbjct: 86 LPSLRFLE-ELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLR 144 Query: 68 LSHNNLSRLRAEWTPTRLTQLHSLL---LSHNHLNFISSEAFSPVPNLRYLDLSSNQLRT 124 L N++S + P+ + LHSL L N L I +AF + L+ + L+ N++ Sbjct: 145 LDANHISYV----PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHH 200 Query: 125 LDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKL 184 + ++ F +L L VL L+NN I ++ + FD + L+ L L+ N + FP + L Sbjct: 201 IPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAI----RTL 256 Query: 185 PKLTLLDLSSNKLKNLPLPDLQKLPAWIKNGLYLHNNPL 223 L L SN ++++P P+ I ++ ++NP+ Sbjct: 257 SNLKELGFHSNNIRSIPEKAFVGNPSLIT--IHFYDNPI 293 Score = 53.1 bits (126), Expect = 6e-07 Identities = 46/146 (31%), Positives = 69/146 (47%), Gaps = 9/146 (6%) Query: 65 LLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRT 124 L L+ N S++ T L SL L+ ++ + + +PNL+ LDLS N L Sbjct: 307 LRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLED 366 Query: 125 LDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGA-- 182 L FS Q L+ + L +N I + F + L+ L L+ N+I+ ++ A Sbjct: 367 LPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIA-----IIHPNAFS 419 Query: 183 KLPKLTLLDLSSNKLKNLPLPDLQKL 208 LP L LDLSSN L + P+ L L Sbjct: 420 TLPSLIKLDLSSNLLSSFPITGLHGL 445 Score = 52.0 bits (123), Expect = 1e-06 Identities = 56/175 (32%), Positives = 82/175 (46%), Gaps = 29/175 (16%) Query: 54 NVPHSLPSYTALLDLS-------HNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAF 106 N H +P Y A +LS HNN + L L +L L++N+L+ + A Sbjct: 196 NKIHHIPDY-AFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT-AI 253 Query: 107 SPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLS 166 + NL+ L SN +R++ E F L + Y+N I V R AF + +L+ L L+ Sbjct: 254 RTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLN 313 Query: 167 -QNQISRFP-------LE-LVKEGA-----------KLPKLTLLDLSSNKLKNLP 201 +QI+ FP LE L GA +LP L +LDLS N L++LP Sbjct: 314 GASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLP 368 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/112 (33%), Positives = 51/112 (45%), Gaps = 8/112 (7%) Query: 84 RLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYN 143 +L L L LS+N L + S FS L+ +DL N++ + F L L L L Sbjct: 350 QLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAW 407 Query: 144 NHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSN 195 N I + AF + L KL LS N +S FP+ L LT L L+ N Sbjct: 408 NKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPI------TGLHGLTHLKLTGN 453 >gi|88702793 slit-like 2 [Homo sapiens] Length = 673 Score = 84.7 bits (208), Expect = 2e-16 Identities = 65/187 (34%), Positives = 91/187 (48%), Gaps = 13/187 (6%) Query: 12 LLLPSLSLLLFEVARAGRAVVSCPAACLCAS-NILSCSKQQLPNVPHSLPSYTALLDLSH 70 LLLP L LL G V CP+ C C+ + C+ +Q VP +P T L + Sbjct: 7 LLLPLLLLLAL-----GPGVQGCPSGCQCSQPQTVFCTARQGTTVPRDVPPDTVGLYVFE 61 Query: 71 NNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLF 130 N ++ L A + L L L LS N + + S F P+ NL LDL++N+L + F Sbjct: 62 NGITMLDAG-SFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETF 120 Query: 131 SDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLL 190 L+ LE L L N I + AFD + +L +L L N++ P +LP+L LL Sbjct: 121 RGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALP------PLRLPRLLLL 174 Query: 191 DLSSNKL 197 DLS N L Sbjct: 175 DLSHNSL 181 Score = 34.7 bits (78), Expect = 0.20 Identities = 22/62 (35%), Positives = 35/62 (56%), Gaps = 3/62 (4%) Query: 139 LLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLK 198 L ++ N I +D +F + LQ L LSQNQI+ P + + L L+ LDL++N+L Sbjct: 57 LYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQ---PLANLSNLDLTANRLH 113 Query: 199 NL 200 + Sbjct: 114 EI 115 >gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens] Length = 708 Score = 84.3 bits (207), Expect = 2e-16 Identities = 76/303 (25%), Positives = 139/303 (45%), Gaps = 27/303 (8%) Query: 85 LTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNN 144 L L S+ N L + A V NL++LDL+ N + + FS++ L+ L + N Sbjct: 235 LENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNM 294 Query: 145 -HIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGA--KLPKLTLLDLSSNKLKNLP 201 ++++D A D++ L+K+ + N L + A +LPKL L L+SN L L Sbjct: 295 PELISIDSLAVDNLPDLRKIEATNNP----RLSYIHPNAFFRLPKLESLMLNSNALSALY 350 Query: 202 LPDLQKLPAWIKNGLYLHNNPLNCDCELYQLFSHWQYRQLSSVMDFQED-LYCMNSKKLH 260 ++ LP + + +H+NP+ CDC + W +++ + D L+C++ + Sbjct: 351 HGTIESLPNLKE--ISIHSNPIRCDCVI-----RWMNMNKTNIRFMEPDSLFCVDPPEFQ 403 Query: 261 --NVFNLSFLNCGEY-----KERAWEAHL----GDTLIIKCDTKQQGMTKV-WVTPSNER 308 NV + F + E ++ ++L G + C + ++ W+TPS ++ Sbjct: 404 GQNVRQVHFRDMMEICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQK 463 Query: 309 VLDEVTNGTVSVSKDGSLLFQQVQVEDGGVYTCYAMGETFNETLSVELKVHNFTLHGHHD 368 +L V +G+L V ++GG+YTC A + SV +KV ++ Sbjct: 464 LLPNTLTDKFYVHSEGTLDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNG 523 Query: 369 TLN 371 +LN Sbjct: 524 SLN 526 Score = 64.3 bits (155), Expect = 2e-10 Identities = 67/269 (24%), Positives = 114/269 (42%), Gaps = 30/269 (11%) Query: 17 LSLLLFEVARAGRAVVSCPAACLCA-------------SNILSCSKQQLPNVPHSLPSYT 63 L L + + +A V CP C C ++ + C+ L P LP+ T Sbjct: 12 LGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANT 71 Query: 64 ALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLR 123 +L L NN++++ E++ L L LS N+L+ +++ +P L + L N+L Sbjct: 72 QILLLQTNNIAKI--EYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLT 129 Query: 124 TLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAK 183 L E S+L L+ L + +N + + AF + L +L+L+ N R + K Sbjct: 130 ELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSN---RLQMINSKWFDA 186 Query: 184 LPKLTLLDLSSN---KLKNLPLPDLQKLPAWIKNGLYLHNNPLNCDCELYQLFSHWQYRQ 240 LP L +L + N ++K++ L L + + G+ L P N L Sbjct: 187 LPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGL---------EN 237 Query: 241 LSSVMDFQEDLYCMNSKKLHNVFNLSFLN 269 L S+ + L + L V NL FL+ Sbjct: 238 LESISFYDNRLIKVPHVALQKVVNLKFLD 266 Score = 58.5 bits (140), Expect = 1e-08 Identities = 52/186 (27%), Positives = 87/186 (46%), Gaps = 11/186 (5%) Query: 39 LCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHL 98 L +N+ S + + +P L Y L N L+ L E + L+ L L ++HN L Sbjct: 99 LSQNNLSSVTNINVKKMPQLLSVY-----LEENKLTEL-PEKCLSELSNLQELYINHNLL 152 Query: 99 NFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMA 158 + IS AF + NL L L+SN+L+ ++ F L LE+L++ N I+ + F + Sbjct: 153 STISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLI 212 Query: 159 QLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIKNGLYL 218 L+ L ++ ++ P + L L + N+L +P LQK+ L L Sbjct: 213 NLRSLVIAGINLTEIPDNAL---VGLENLESISFYDNRLIKVPHVALQKVVN--LKFLDL 267 Query: 219 HNNPLN 224 + NP+N Sbjct: 268 NKNPIN 273 >gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens] Length = 708 Score = 84.3 bits (207), Expect = 2e-16 Identities = 76/303 (25%), Positives = 139/303 (45%), Gaps = 27/303 (8%) Query: 85 LTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNN 144 L L S+ N L + A V NL++LDL+ N + + FS++ L+ L + N Sbjct: 235 LENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNM 294 Query: 145 -HIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGA--KLPKLTLLDLSSNKLKNLP 201 ++++D A D++ L+K+ + N L + A +LPKL L L+SN L L Sbjct: 295 PELISIDSLAVDNLPDLRKIEATNNP----RLSYIHPNAFFRLPKLESLMLNSNALSALY 350 Query: 202 LPDLQKLPAWIKNGLYLHNNPLNCDCELYQLFSHWQYRQLSSVMDFQED-LYCMNSKKLH 260 ++ LP + + +H+NP+ CDC + W +++ + D L+C++ + Sbjct: 351 HGTIESLPNLKE--ISIHSNPIRCDCVI-----RWMNMNKTNIRFMEPDSLFCVDPPEFQ 403 Query: 261 --NVFNLSFLNCGEY-----KERAWEAHL----GDTLIIKCDTKQQGMTKV-WVTPSNER 308 NV + F + E ++ ++L G + C + ++ W+TPS ++ Sbjct: 404 GQNVRQVHFRDMMEICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQK 463 Query: 309 VLDEVTNGTVSVSKDGSLLFQQVQVEDGGVYTCYAMGETFNETLSVELKVHNFTLHGHHD 368 +L V +G+L V ++GG+YTC A + SV +KV ++ Sbjct: 464 LLPNTLTDKFYVHSEGTLDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNG 523 Query: 369 TLN 371 +LN Sbjct: 524 SLN 526 Score = 64.3 bits (155), Expect = 2e-10 Identities = 67/269 (24%), Positives = 114/269 (42%), Gaps = 30/269 (11%) Query: 17 LSLLLFEVARAGRAVVSCPAACLCA-------------SNILSCSKQQLPNVPHSLPSYT 63 L L + + +A V CP C C ++ + C+ L P LP+ T Sbjct: 12 LGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANT 71 Query: 64 ALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLR 123 +L L NN++++ E++ L L LS N+L+ +++ +P L + L N+L Sbjct: 72 QILLLQTNNIAKI--EYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLT 129 Query: 124 TLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAK 183 L E S+L L+ L + +N + + AF + L +L+L+ N R + K Sbjct: 130 ELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSN---RLQMINSKWFDA 186 Query: 184 LPKLTLLDLSSN---KLKNLPLPDLQKLPAWIKNGLYLHNNPLNCDCELYQLFSHWQYRQ 240 LP L +L + N ++K++ L L + + G+ L P N L Sbjct: 187 LPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGL---------EN 237 Query: 241 LSSVMDFQEDLYCMNSKKLHNVFNLSFLN 269 L S+ + L + L V NL FL+ Sbjct: 238 LESISFYDNRLIKVPHVALQKVVNLKFLD 266 Score = 58.5 bits (140), Expect = 1e-08 Identities = 52/186 (27%), Positives = 87/186 (46%), Gaps = 11/186 (5%) Query: 39 LCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHL 98 L +N+ S + + +P L Y L N L+ L E + L+ L L ++HN L Sbjct: 99 LSQNNLSSVTNINVKKMPQLLSVY-----LEENKLTEL-PEKCLSELSNLQELYINHNLL 152 Query: 99 NFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMA 158 + IS AF + NL L L+SN+L+ ++ F L LE+L++ N I+ + F + Sbjct: 153 STISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLI 212 Query: 159 QLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIKNGLYL 218 L+ L ++ ++ P + L L + N+L +P LQK+ L L Sbjct: 213 NLRSLVIAGINLTEIPDNAL---VGLENLESISFYDNRLIKVPHVALQKVVN--LKFLDL 267 Query: 219 HNNPLN 224 + NP+N Sbjct: 268 NKNPIN 273 >gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens] Length = 708 Score = 84.3 bits (207), Expect = 2e-16 Identities = 76/303 (25%), Positives = 139/303 (45%), Gaps = 27/303 (8%) Query: 85 LTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNN 144 L L S+ N L + A V NL++LDL+ N + + FS++ L+ L + N Sbjct: 235 LENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNM 294 Query: 145 -HIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGA--KLPKLTLLDLSSNKLKNLP 201 ++++D A D++ L+K+ + N L + A +LPKL L L+SN L L Sbjct: 295 PELISIDSLAVDNLPDLRKIEATNNP----RLSYIHPNAFFRLPKLESLMLNSNALSALY 350 Query: 202 LPDLQKLPAWIKNGLYLHNNPLNCDCELYQLFSHWQYRQLSSVMDFQED-LYCMNSKKLH 260 ++ LP + + +H+NP+ CDC + W +++ + D L+C++ + Sbjct: 351 HGTIESLPNLKE--ISIHSNPIRCDCVI-----RWMNMNKTNIRFMEPDSLFCVDPPEFQ 403 Query: 261 --NVFNLSFLNCGEY-----KERAWEAHL----GDTLIIKCDTKQQGMTKV-WVTPSNER 308 NV + F + E ++ ++L G + C + ++ W+TPS ++ Sbjct: 404 GQNVRQVHFRDMMEICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQK 463 Query: 309 VLDEVTNGTVSVSKDGSLLFQQVQVEDGGVYTCYAMGETFNETLSVELKVHNFTLHGHHD 368 +L V +G+L V ++GG+YTC A + SV +KV ++ Sbjct: 464 LLPNTLTDKFYVHSEGTLDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNG 523 Query: 369 TLN 371 +LN Sbjct: 524 SLN 526 Score = 64.3 bits (155), Expect = 2e-10 Identities = 67/269 (24%), Positives = 114/269 (42%), Gaps = 30/269 (11%) Query: 17 LSLLLFEVARAGRAVVSCPAACLCA-------------SNILSCSKQQLPNVPHSLPSYT 63 L L + + +A V CP C C ++ + C+ L P LP+ T Sbjct: 12 LGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANT 71 Query: 64 ALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLR 123 +L L NN++++ E++ L L LS N+L+ +++ +P L + L N+L Sbjct: 72 QILLLQTNNIAKI--EYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLT 129 Query: 124 TLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAK 183 L E S+L L+ L + +N + + AF + L +L+L+ N R + K Sbjct: 130 ELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSN---RLQMINSKWFDA 186 Query: 184 LPKLTLLDLSSN---KLKNLPLPDLQKLPAWIKNGLYLHNNPLNCDCELYQLFSHWQYRQ 240 LP L +L + N ++K++ L L + + G+ L P N L Sbjct: 187 LPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGL---------EN 237 Query: 241 LSSVMDFQEDLYCMNSKKLHNVFNLSFLN 269 L S+ + L + L V NL FL+ Sbjct: 238 LESISFYDNRLIKVPHVALQKVVNLKFLD 266 Score = 58.5 bits (140), Expect = 1e-08 Identities = 52/186 (27%), Positives = 87/186 (46%), Gaps = 11/186 (5%) Query: 39 LCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHL 98 L +N+ S + + +P L Y L N L+ L E + L+ L L ++HN L Sbjct: 99 LSQNNLSSVTNINVKKMPQLLSVY-----LEENKLTEL-PEKCLSELSNLQELYINHNLL 152 Query: 99 NFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMA 158 + IS AF + NL L L+SN+L+ ++ F L LE+L++ N I+ + F + Sbjct: 153 STISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLI 212 Query: 159 QLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIKNGLYL 218 L+ L ++ ++ P + L L + N+L +P LQK+ L L Sbjct: 213 NLRSLVIAGINLTEIPDNAL---VGLENLESISFYDNRLIKVPHVALQKVVN--LKFLDL 267 Query: 219 HNNPLN 224 + NP+N Sbjct: 268 NKNPIN 273 >gi|13375646 leucine rich repeat and fibronectin type III domain containing 3 [Homo sapiens] Length = 628 Score = 84.0 bits (206), Expect = 3e-16 Identities = 103/372 (27%), Positives = 152/372 (40%), Gaps = 63/372 (16%) Query: 34 CPAACLCASNILS----CSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLH 89 CP C C + L C L VP SL A L L+ N ++ +R +T L Sbjct: 28 CPRRCRCQTQSLPLSVLCPGAGLLFVPPSLDRRAAELRLADNFIASVRRR-DLANMTGLL 86 Query: 90 SLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAV 149 L LS N + +++ AF+ + LR L L N+L +L E L L L+L NN + A+ Sbjct: 87 HLSLSRNTIRHVAAGAFADLRALRALHLDGNRLTSLGEGQLRGLVNLRHLILSNNQLAAL 146 Query: 150 DRCAFDDMAQ-LQKLYLSQNQISRFPLEL-------------------VKEGA--KLPKL 187 A DD A+ L+ L LS N + + P E V GA +L KL Sbjct: 147 AAGALDDCAETLEDLDLSYNNLEQLPWEALGRLGNVNTLGLDHNLLASVPAGAFSRLHKL 206 Query: 188 TLLDLSSNKLKNLPL-PDLQKLPAWIKNG--------LYLHNNPLNCDCELYQLFSHWQY 238 LD++SN+L +P P +LP + L NPL+C+CEL L Sbjct: 207 ARLDMTSNRLTTIPPDPLFSRLPLLARPRGSPASALVLAFGGNPLHCNCELVWL------ 260 Query: 239 RQLSSVMDFQEDLYCMNSKKLHNVFNLSFLNCGE-----------YKERAWEAHLGDTLI 287 R+L+ D + C + L + F GE ++ G Sbjct: 261 RRLAREDDLEA---CASPPALGGRY---FWAVGEEEFVCEPPVVTHRSPPLAVPAGRPAA 314 Query: 288 IKCDTKQQGMTKV-WVTPSNERVLDEVTNGTVSVSKDGSLLFQQVQVEDGGVYTCYAMGE 346 ++C +V WV+P R+L + +G+L + DGG++TC A Sbjct: 315 LRCRAVGDPEPRVRWVSPQG-RLLG--NSSRARAFPNGTLELLVTEPGDGGIFTCIAANA 371 Query: 347 TFNETLSVELKV 358 T +VEL V Sbjct: 372 AGEATAAVELTV 383 >gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1 [Homo sapiens] Length = 1093 Score = 80.9 bits (198), Expect = 2e-15 Identities = 66/212 (31%), Positives = 97/212 (45%), Gaps = 31/212 (14%) Query: 10 LWLLLPSLSLLLFEVARAGRAVVSCPAACLCASNILSCSKQQLPNVPHSLPSYTALLDLS 69 LWLLL L L V A C AAC CA + L C + L +P LPS+T L+LS Sbjct: 21 LWLLL----LRLEPVTAAAGPRAPCAAACTCAGDSLDCGGRGLAALPGDLPSWTRSLNLS 76 Query: 70 HNNLSRL-----------------RAEWTP-----TRLTQLHSLLLSHNHLNFISSEAFS 107 +N LS + E T + + SL L HN + + Sbjct: 77 YNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLQHNKIRSVEGSQLK 136 Query: 108 PVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQ-LQKLYLS 166 +L LDLS N + + F ++ L L N I ++ AFD +++ L L LS Sbjct: 137 AYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLS 196 Query: 167 QNQISRFPLELVKEGAKLPKLTLLDLSSNKLK 198 +N+I++ P+ KLP+LT LDL+ N+++ Sbjct: 197 KNRITQLPV----RAFKLPRLTQLDLNRNRIR 224 Score = 54.7 bits (130), Expect = 2e-07 Identities = 45/136 (33%), Positives = 68/136 (50%), Gaps = 1/136 (0%) Query: 65 LLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRT 124 +L L +N+L + + + LT LH L LS+N + I + +S L L LS N L Sbjct: 263 VLHLEYNSLVEVNSG-SLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTR 321 Query: 125 LDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKL 184 LDE ++L L VL L +N I + AF + L+ L L N+IS + + L Sbjct: 322 LDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGL 381 Query: 185 PKLTLLDLSSNKLKNL 200 L+ L L NK+K++ Sbjct: 382 DSLSKLTLFGNKIKSV 397 Score = 50.1 bits (118), Expect = 5e-06 Identities = 43/137 (31%), Positives = 70/137 (51%), Gaps = 12/137 (8%) Query: 65 LLDLSHNNLSRLR--AEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQL 122 +L L NN+S+L A W L+++H L L +N L ++S + + L L LS+N + Sbjct: 239 VLKLQRNNISKLTDGAFWG---LSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSI 295 Query: 123 RTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGA 182 + +S Q L L+L N++ +D + +++ L L LS N IS + EGA Sbjct: 296 ARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISH-----IAEGA 350 Query: 183 --KLPKLTLLDLSSNKL 197 L L +LDL N++ Sbjct: 351 FKGLRSLRVLDLDHNEI 367 Score = 47.4 bits (111), Expect = 3e-05 Identities = 43/147 (29%), Positives = 67/147 (45%), Gaps = 10/147 (6%) Query: 56 PHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYL 115 PH P L+L+ N + L L +L LS N + + AF +P L L Sbjct: 160 PHGPPIKE--LNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQL 216 Query: 116 DLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPL 175 DL+ N++R ++ F L LEVL L N+I + AF ++++ L+L N + Sbjct: 217 DLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVE--- 273 Query: 176 ELVKEGA--KLPKLTLLDLSSNKLKNL 200 V G+ L L L LS+N + + Sbjct: 274 --VNSGSLYGLTALHQLHLSNNSIARI 298 >gi|139948432 adlican [Homo sapiens] Length = 2828 Score = 80.9 bits (198), Expect = 2e-15 Identities = 68/271 (25%), Positives = 122/271 (45%), Gaps = 20/271 (7%) Query: 16 SLSLLLFEVARAGRAVVSCPAACLC-ASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLS 74 +LS++L + R ++CP C C + + C+ + L +VP + + ++L N++ Sbjct: 9 ALSVVLILLWGHPRVALACPHPCACYVPSEVHCTFRSLASVPAGIAKHVERINLGFNSIQ 68 Query: 75 RLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQ 134 L +E + LT+L L++ N + I A + +L+ S N+LR + L Sbjct: 69 AL-SETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLRVITGQTLQGLS 127 Query: 135 VLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQI-----SRFPLELVKEGAKLPKLTL 189 L L + +N I + AF+ + L+ L+L N + S F + +L + Sbjct: 128 NLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTFLDYFRLSTIRH 187 Query: 190 LDLSSNKLKNLPLPDLQKLPAWIKNGLYLHNNPLNCDCELYQLFSHWQYRQLSSVMDFQE 249 L L+ N ++ LP L+ +P + LYL NP CDCE+ + F W + + ++ Sbjct: 188 LYLAENMVRTLPASMLRNMP--LLENLYLQGNPWTCDCEM-RWFLEWDAKSRGILKCKKD 244 Query: 250 DLY--------CMNSKKL--HNVFNLSFLNC 270 Y C + KKL H + L + C Sbjct: 245 KAYEGGQLCAMCFSPKKLYKHEIHKLKDMTC 275 Score = 47.4 bits (111), Expect = 3e-05 Identities = 35/139 (25%), Positives = 67/139 (48%), Gaps = 9/139 (6%) Query: 283 GDTLIIKCDTKQQGMTKV-WVTPSNERVLDEVTNGTVSVSKDGSLLFQQVQVEDGGVYTC 341 GD + + C+ K + M KV W++P+N+ + ++ + +DG+LL Q+ Q D G YTC Sbjct: 2361 GDVVTVACEAKGEPMPKVTWLSPTNKVI--PTSSEKYQIYQDGTLLIQKAQRSDSGNYTC 2418 Query: 342 Y---AMGETFNETLSVELKVHNFTLHGHHDTLNTAYTTLVGCILSVVLVLIYLYLTPCRC 398 + GE +T+ + + V ++G+ + + T G ++ TP Sbjct: 2419 LVRNSAGED-RKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVL 2477 Query: 399 WC--RGVEKPSSHQGDSLS 415 W GV P+ + G+ ++ Sbjct: 2478 WAFPEGVVLPAPYYGNRIT 2496 Score = 37.0 bits (84), Expect = 0.041 Identities = 22/81 (27%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Query: 281 HLGDTLIIKCDTKQQGMTKV-WVTPSNERVLDEVT--NGTVSVSKDGSLLFQQVQVEDGG 337 +LGDT+ ++C K ++ W+ P + RV V+ G +++ ++ +L ++ D G Sbjct: 1963 YLGDTIAMECLAKGTPAPQISWIFP-DRRVWQTVSPVEGRITLHENRTLSIKEASFSDRG 2021 Query: 338 VYTCYAMGETFNETLSVELKV 358 VY C A ++L++ L V Sbjct: 2022 VYKCVASNAAGADSLAIRLHV 2042 Score = 34.7 bits (78), Expect = 0.20 Identities = 18/59 (30%), Positives = 34/59 (57%), Gaps = 2/59 (3%) Query: 301 WVTPSNERVLDEVTNGT-VSVSKDGSLLFQQVQVEDGGVYTCYAMGETFNETLSVELKV 358 W+ P N R+++++ N + V + +G+L +VQV D G Y C A+ + + +V + V Sbjct: 611 WILP-NRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQGADHFTVGITV 668 Score = 33.1 bits (74), Expect = 0.59 Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 1/60 (1%) Query: 283 GDTLIIKCDTKQQGMTKV-WVTPSNERVLDEVTNGTVSVSKDGSLLFQQVQVEDGGVYTC 341 G+TL + C G + W P+ + T G VS+ +G+L ++ V D G Y C Sbjct: 2652 GETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVC 2711 Score = 30.8 bits (68), Expect = 2.9 Identities = 13/39 (33%), Positives = 23/39 (58%) Query: 320 VSKDGSLLFQQVQVEDGGVYTCYAMGETFNETLSVELKV 358 V +G+L F +V + + G YTC+A + + + V +KV Sbjct: 2303 VFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKV 2341 Score = 29.6 bits (65), Expect = 6.6 Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 4/86 (4%) Query: 276 RAWEAHLGDTLIIKCDTKQQGMTKV-WVTPSNERVLDEVTN--GTVSVSKDGSLLFQQVQ 332 R + G TL + C ++ W PS +R++D + + + V +G+L+ + V Sbjct: 2154 RRTDVRYGGTLKLDCSASGDPWPRILWRLPS-KRMIDALFSFDSRIKVFANGTLVVKSVT 2212 Query: 333 VEDGGVYTCYAMGETFNETLSVELKV 358 +D G Y C A + ++ + +++ V Sbjct: 2213 DKDAGDYLCVARNKVGDDYVVLKVDV 2238 >gi|5729718 trophoblast glycoprotein [Homo sapiens] Length = 420 Score = 80.1 bits (196), Expect = 4e-15 Identities = 77/276 (27%), Positives = 113/276 (40%), Gaps = 54/276 (19%) Query: 34 CPAACLC--ASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTR--LTQLH 89 CPA C C A+ + C + L VP LP+Y L L+ N L+ L A R L +L Sbjct: 62 CPALCECSEAARTVKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARRPPLAELA 121 Query: 90 SLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSD----------------- 132 +L LS + L+ + + AF +P+LR LDLS N L L F FS Sbjct: 122 ALNLSGSRLDEVRAGAFEHLPSLRQLDLSHNPLADLSPFAFSGSNASVSAPSPLVELILN 181 Query: 133 ---------------------------LQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYL 165 LQ L L L +NH + + R + L+ L L Sbjct: 182 HIVPPEDERQNRSFEGMVVAALLAGRALQGLRRLELASNHFLYLPRDVLAQLPSLRHLDL 241 Query: 166 SQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIKNGLYLHNNPLNC 225 S N + + L L L D + L N L +LQ LP ++L NNP C Sbjct: 242 SNNSLVSLTYVSFRNLTHLESLHLEDNALKVLHNGTLAELQGLP---HIRVFLDNNPWVC 298 Query: 226 DCELYQLFSHWQYRQLSSVMDFQEDLYCMNSKKLHN 261 DC + + + + + + V+ ++ L C +K+ N Sbjct: 299 DCHMADMVT---WLKETEVVQGKDRLTCAYPEKMRN 331 >gi|113423021 PREDICTED: similar to hCG1820409 [Homo sapiens] Length = 578 Score = 79.0 bits (193), Expect = 9e-15 Identities = 76/242 (31%), Positives = 103/242 (42%), Gaps = 38/242 (15%) Query: 15 PSLSLLLFEVARAGRAVVSCPAACLCASN---ILSC-SKQQLPNVPHSLPSYTALLDLSH 70 P L LL A + CP C C +L C S +L P +P L + Sbjct: 204 PGLQGLLLVAAALSQPAAPCPFQCYCFGGPKLLLRCASGAELRQPPRDVPPDARNLTIVG 263 Query: 71 NNLSRLRA-----------EWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSS 119 NL+ LRA + RL L +L L+HNH+ + AF +P+L LDLS Sbjct: 264 ANLTVLRAAAFAGGDGDGDQAAGVRLPLLSALRLTHNHIEVVEDGAFDGLPSLAALDLSH 323 Query: 120 NQLRTLDEFLFSDLQVLEVLLLYNNH--------IMAVDRCAFDDMAQLQKLYLSQNQIS 171 N LR L F L L L L NH ++A A +A+L+ L L+ N +S Sbjct: 324 NPLRALGGGAFRGLPALRSLQL--NHALVRGGPALLAALDAALAPLAELRLLGLAGNALS 381 Query: 172 RFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIKNG------LYLHNNPLNC 225 R P +L +L LD+ N L L D +L A ++G L L +NPL C Sbjct: 382 RLP----PAALRLARLEQLDVRLNALAGL---DPDELRALERDGGLPGPRLLLADNPLRC 434 Query: 226 DC 227 C Sbjct: 435 GC 436 >gi|113422497 PREDICTED: similar to hCG1820409 [Homo sapiens] Length = 578 Score = 79.0 bits (193), Expect = 9e-15 Identities = 76/242 (31%), Positives = 103/242 (42%), Gaps = 38/242 (15%) Query: 15 PSLSLLLFEVARAGRAVVSCPAACLCASN---ILSC-SKQQLPNVPHSLPSYTALLDLSH 70 P L LL A + CP C C +L C S +L P +P L + Sbjct: 204 PGLQGLLLVAAALSQPAAPCPFQCYCFGGPKLLLRCASGAELRQPPRDVPPDARNLTIVG 263 Query: 71 NNLSRLRA-----------EWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSS 119 NL+ LRA + RL L +L L+HNH+ + AF +P+L LDLS Sbjct: 264 ANLTVLRAAAFAGGDGDGDQAAGVRLPLLSALRLTHNHIEVVEDGAFDGLPSLAALDLSH 323 Query: 120 NQLRTLDEFLFSDLQVLEVLLLYNNH--------IMAVDRCAFDDMAQLQKLYLSQNQIS 171 N LR L F L L L L NH ++A A +A+L+ L L+ N +S Sbjct: 324 NPLRALGGGAFRGLPALRSLQL--NHALVRGGPALLAALDAALAPLAELRLLGLAGNALS 381 Query: 172 RFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPDLQKLPAWIKNG------LYLHNNPLNC 225 R P +L +L LD+ N L L D +L A ++G L L +NPL C Sbjct: 382 RLP----PAALRLARLEQLDVRLNALAGL---DPDELRALERDGGLPGPRLLLADNPLRC 434 Query: 226 DC 227 C Sbjct: 435 GC 436 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.135 0.415 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,126,494 Number of Sequences: 37866 Number of extensions: 957403 Number of successful extensions: 5234 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 243 Number of HSP's successfully gapped in prelim test: 151 Number of HSP's that attempted gapping in prelim test: 3045 Number of HSP's gapped (non-prelim): 1311 length of query: 493 length of database: 18,247,518 effective HSP length: 106 effective length of query: 387 effective length of database: 14,233,722 effective search space: 5508450414 effective search space used: 5508450414 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.