Guide to the Human Genome
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Search of human proteins with 153791158

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153791158 keratin 75 [Homo sapiens]
         (551 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153791158 keratin 75 [Homo sapiens]                               1066   0.0  
gi|119395754 keratin 5 [Homo sapiens]                                 810   0.0  
gi|5031839 keratin 6A [Homo sapiens]                                  778   0.0  
gi|155969697 keratin 6C [Homo sapiens]                                775   0.0  
gi|119703753 keratin 6B [Homo sapiens]                                772   0.0  
gi|109255249 keratin 4 [Homo sapiens]                                 628   e-180
gi|109148552 keratin 3 [Homo sapiens]                                 613   e-175
gi|153791670 keratin 76 [Homo sapiens]                                608   e-174
gi|32567786 keratin 6L [Homo sapiens]                                 600   e-171
gi|119395750 keratin 1 [Homo sapiens]                                 584   e-167
gi|47132620 keratin 2 [Homo sapiens]                                  575   e-164
gi|194018511 keratin 77 [Homo sapiens]                                575   e-164
gi|15618995 keratin 71 [Homo sapiens]                                 563   e-160
gi|28173564 keratin 73 [Homo sapiens]                                 559   e-159
gi|148612803 keratin 6 irs4 [Homo sapiens]                            551   e-157
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       548   e-156
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      548   e-156
gi|67782365 keratin 7 [Homo sapiens]                                  523   e-148
gi|4504919 keratin 8 [Homo sapiens]                                   522   e-148
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    509   e-144
gi|89357932 keratin 5b [Homo sapiens]                                 473   e-133
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      468   e-132
gi|4504935 keratin 85 [Homo sapiens]                                  453   e-127
gi|27477127 keratin 82 [Homo sapiens]                                 451   e-127
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   430   e-120
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   424   e-118
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   424   e-118
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   424   e-118
gi|14318422 keratin 86 [Homo sapiens]                                 424   e-118
gi|169790841 keratin 83 [Homo sapiens]                                420   e-117

>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score = 1066 bits (2757), Expect = 0.0
 Identities = 551/551 (100%), Positives = 551/551 (100%)

Query: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR 60
           MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR
Sbjct: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR 60

Query: 61  SLYNLGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGG 120
           SLYNLGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGG
Sbjct: 61  SLYNLGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGG 120

Query: 121 IQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETK 180
           IQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETK
Sbjct: 121 IQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETK 180

Query: 181 WALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYE 240
           WALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYE
Sbjct: 181 WALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYE 240

Query: 241 DEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVG 300
           DEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVG
Sbjct: 241 DEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVG 300

Query: 301 DTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDL 360
           DTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDL
Sbjct: 301 DTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDL 360

Query: 361 RNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEAL 420
           RNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEAL
Sbjct: 361 RNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEAL 420

Query: 421 QKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLS 480
           QKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLS
Sbjct: 421 QKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLS 480

Query: 481 SGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSSVKFVS 540
           SGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSSVKFVS
Sbjct: 481 SGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSSVKFVS 540

Query: 541 TTSSSQKSYTH 551
           TTSSSQKSYTH
Sbjct: 541 TTSSSQKSYTH 551


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  810 bits (2093), Expect = 0.0
 Identities = 438/589 (74%), Positives = 481/589 (81%), Gaps = 41/589 (6%)

Query: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGA----S 56
           MSRQSS++F+SG  R FST SAITP+  R+ F+SVS +    G GG GR+S AGA     
Sbjct: 1   MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRS-GGGGGGGFGRVSLAGACGVGG 59

Query: 57  FGSRSLYNLGGAKRVSINGCGSSCRSGFGGRASNRFG----VNSGFGYGGGVGGGFS--- 109
           +GSRSLYNLGG+KR+SI+  G S R+ FG  A   +G      SGFG+GGG GGGF    
Sbjct: 60  YGSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGG 119

Query: 110 ---------GPSFPVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKF 160
                    GP FPVCPPGGIQEVTVNQSLLTPL+LQIDP+IQRVR EEREQIKTLNNKF
Sbjct: 120 GAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKF 179

Query: 161 ASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGR 220
           ASFIDKVRFLEQQNKVL+TKW LLQEQG++TVRQNLEPLF+ Y + LRRQL+SI  ERGR
Sbjct: 180 ASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGR 239

Query: 221 LEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEE 280
           L++ELRNMQD+VEDFK +YEDEINKRT AENEFV LKKDVDAAYMNKVELEAKV +L +E
Sbjct: 240 LDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDE 299

Query: 281 INFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAES 340
           INF+   FDAELSQ+QT V DTSVVLSMDNNRNLDLDSIIAEVKAQYE+IANRSR EAES
Sbjct: 300 INFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAES 359

Query: 341 WYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQ 400
           WYQTKYEELQ TAGRHGDDLRNTK EISEMNRMIQRLRAEID+VKKQC++LQ AIADAEQ
Sbjct: 360 WYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQ 419

Query: 401 RGELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEEC 460
           RGELALKDAR KL +LEEALQKAKQDMARLLREYQELMN KLALDVEIATYRKLLEGEEC
Sbjct: 420 RGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEEC 479

Query: 461 RLSGEGVSPVNISVVTSTLSSGYGSGSSIGGG-NLGLGGGSG----------YSFTTSGG 509
           RLSGEGV PVNISVVTS++SSGYGSGS  GGG   GLGGG G          Y  ++SGG
Sbjct: 480 RLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGG 539

Query: 510 HSLGAGL--GGSGFSATSNRGL-------GGSGSSVKFVSTTSSSQKSY 549
             LG GL  GGSGFSA+S RGL       GGS SSVKFVSTTSSS+KS+
Sbjct: 540 VGLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSSRKSF 588


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  778 bits (2008), Expect = 0.0
 Identities = 412/573 (71%), Positives = 467/573 (81%), Gaps = 34/573 (5%)

Query: 2   SRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRS 61
           S  ++I   S SRRGFS  SA  P   RS FSSVSV+RS  GSGGLG  +  GA FGSRS
Sbjct: 3   STSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSR-GSGGLGG-ACGGAGFGSRS 60

Query: 62  LYNLGGAKRVSINGCGSSCRSGFGGRASNRFG---VNSGFGYGGGVG------------G 106
           LY LGG+KR+SI G   +   G+G RA   +G     SGFG+GGG G            G
Sbjct: 61  LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG 120

Query: 107 GFSGPSFPVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDK 166
           GF GP FPVCPPGGIQEVTVNQSLLTPL+LQIDPTIQRVRAEEREQIKTLNNKFASFIDK
Sbjct: 121 GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDK 180

Query: 167 VRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELR 226
           VRFLEQQNKVLETKW LLQEQG++TVRQNLEPLF+ Y + LRRQL+SI  ERGRL++ELR
Sbjct: 181 VRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELR 240

Query: 227 NMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHS 286
            MQD+VEDFK +YEDEINKRTAAENEFV LKKDVDAAYMNKVEL+AK  +L +EINF+ +
Sbjct: 241 GMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRA 300

Query: 287 VFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKY 346
           ++DAELSQ+QT + DTSVVLSMDNNRNLDLDSIIAEVKAQYE+IA RSRAEAESWYQTKY
Sbjct: 301 LYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKY 360

Query: 347 EELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELAL 406
           EELQVTAGRHGDDLRNTKQEI+E+NRMIQRLR+EID VKKQC++LQ AIADAEQRGE+AL
Sbjct: 361 EELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMAL 420

Query: 407 KDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEG 466
           KDA+ KL  LE+ALQKAKQD+ARLL+EYQELMN+KLALDVEIATYRKLLEGEECRL+GEG
Sbjct: 421 KDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG 480

Query: 467 VSPVNISVVTSTLSSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLG-GSGFSATS 525
           V  VNISVV ST+SSGYG  S +G G LGLGGGS YS+        G+GLG G GFS++S
Sbjct: 481 VGQVNISVVQSTVSSGYGGASGVGSG-LGLGGGSSYSY--------GSGLGVGGGFSSSS 531

Query: 526 NRGL-------GGSGSSVKFVSTTSSSQKSYTH 551
            R +       GG  S++K+ +T+SSS+KSY H
Sbjct: 532 GRAIGGGLSSVGGGSSTIKYTTTSSSSRKSYKH 564


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  775 bits (2002), Expect = 0.0
 Identities = 409/573 (71%), Positives = 466/573 (81%), Gaps = 34/573 (5%)

Query: 2   SRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRS 61
           S  ++I   S SRRGFS  SA  P   RS FSS+SV+RS  GSGGLG  +  GA FGSRS
Sbjct: 3   STSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSR-GSGGLGG-ACGGAGFGSRS 60

Query: 62  LYNLGGAKRVSINGCGSSCRSGFGGRASNRFG---VNSGFGYGGGVG------------G 106
           LY LGG+KR+SI G   +   G+G RA   +G     SGFG+GGG G            G
Sbjct: 61  LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG 120

Query: 107 GFSGPSFPVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDK 166
           GF GP FPVCPPGGIQEVTVNQSLLTPL+LQIDP IQRVRAEEREQIKTLNNKFASFIDK
Sbjct: 121 GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDK 180

Query: 167 VRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELR 226
           VRFLEQQNKVL+TKW LLQEQG++TVRQNLEPLF+ Y + LRRQL+SI  ERGRL++ELR
Sbjct: 181 VRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELR 240

Query: 227 NMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHS 286
           NMQD+VED K +YEDEINKRTAAENEFV LKKDVDAAYMNKVEL+AK  +L +EINF+ +
Sbjct: 241 NMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRA 300

Query: 287 VFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKY 346
           ++DAELSQ+QT + DTSVVLSMDNNRNLDLDSIIAEVKAQYE+IA RSRAEAESWYQTKY
Sbjct: 301 LYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKY 360

Query: 347 EELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELAL 406
           EELQVTAGRHGDDLRNTKQEI+E+NRMIQRLR+EID VKKQC+SLQ AIADAEQRGE+AL
Sbjct: 361 EELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMAL 420

Query: 407 KDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEG 466
           KDA+ KL  LE+ALQKAKQD+ARLL+EYQELMN+KLALDVEIATYRKLLEGEECRL+GEG
Sbjct: 421 KDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG 480

Query: 467 VSPVNISVVTSTLSSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLG-GSGFSATS 525
           V  VN+SVV ST+SSGYG  S +G G LGLGGGS YS+        G+GLG G GFS++S
Sbjct: 481 VGQVNVSVVQSTISSGYGGASGVGSG-LGLGGGSSYSY--------GSGLGIGGGFSSSS 531

Query: 526 NRGL-------GGSGSSVKFVSTTSSSQKSYTH 551
            R +       GG  S++K+ +T+SSS+KSY H
Sbjct: 532 GRAIGGGLSSVGGGSSTIKYTTTSSSSRKSYKH 564


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  772 bits (1994), Expect = 0.0
 Identities = 407/573 (71%), Positives = 466/573 (81%), Gaps = 34/573 (5%)

Query: 2   SRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRS 61
           S  ++I   S SRRGFS  SA  P   RS FSS+SV+RS  GSGGLG  +  GA FGSRS
Sbjct: 3   STSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSR-GSGGLGG-ACGGAGFGSRS 60

Query: 62  LYNLGGAKRVSINGCGSSCRSGFGGRASNRFG---VNSGFGYGGGVG------------G 106
           LY LGG+KR+SI G   +   G+G RA   +G     SGFG+GGG G            G
Sbjct: 61  LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG 120

Query: 107 GFSGPSFPVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDK 166
           GF GP FPVCPPGGIQEVTVNQSLLTPL+LQIDP IQRVRAEEREQIKTLNNKFASFIDK
Sbjct: 121 GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDK 180

Query: 167 VRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELR 226
           VRFLEQQNKVL+TKW LLQEQG++TVRQNLEPLF+ Y + LRRQL++I  ERGRL++ELR
Sbjct: 181 VRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELR 240

Query: 227 NMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHS 286
           NMQD+VED K +YEDEINKRTAAENEFV LKKDVDAAYMNKVEL+AK  +L +EINF+ +
Sbjct: 241 NMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRA 300

Query: 287 VFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKY 346
           ++DAELSQ+QT + DTSVVLSMDNNRNLDLDSIIAEVKAQYE+IA RSRAEAESWYQTKY
Sbjct: 301 LYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKY 360

Query: 347 EELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELAL 406
           EELQ+TAGRHGDDLRNTKQEI+E+NRMIQRLR+EID VKKQC++LQ AIADAEQRGE+AL
Sbjct: 361 EELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMAL 420

Query: 407 KDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEG 466
           KDA+ KL  LE+ALQKAKQD+ARLL+EYQELMN+KLALDVEIATYRKLLEGEECRL+GEG
Sbjct: 421 KDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG 480

Query: 467 VSPVNISVVTSTLSSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLG-GSGFSATS 525
           V  VNISVV ST+SSGYG  S +G G LGLGGGS YS+        G+GLG G GFS++S
Sbjct: 481 VGQVNISVVQSTVSSGYGGASGVGSG-LGLGGGSSYSY--------GSGLGVGGGFSSSS 531

Query: 526 NR-------GLGGSGSSVKFVSTTSSSQKSYTH 551
            R        +GG  S++K+ +T+SSS+KSY H
Sbjct: 532 GRATGGGLSSVGGGSSTIKYTTTSSSSRKSYKH 564


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  628 bits (1619), Expect = e-180
 Identities = 339/539 (62%), Positives = 417/539 (77%), Gaps = 32/539 (5%)

Query: 12  GSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLYNLGGAKRV 71
           G  RGFS  SAI     R  FSSVS+      SGG GR SS G  FGSRSLYNL G K +
Sbjct: 84  GGPRGFSCGSAIVGGGKRGAFSSVSM------SGGAGRCSSGG--FGSRSLYNLRGNKSI 135

Query: 72  SINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSG---PSFPVCPPGGIQEVTVNQ 128
           S++  GS   + FGG     FG     G+GGG GG FSG   P FPVCP GGIQEVT+NQ
Sbjct: 136 SMSVAGSRQGACFGGAGG--FGTG---GFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQ 190

Query: 129 SLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQG 188
           SLLTPLH++IDP IQ+VR EEREQIK LNNKFASFIDKV+FLEQQNKVLETKW LLQ+Q 
Sbjct: 191 SLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQT 250

Query: 189 SRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTA 248
           + T  +NLEPLF++Y S LR+QL+++  ++GRL++EL+ MQD VEDFK +YE+EINKRTA
Sbjct: 251 TTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTA 310

Query: 249 AENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSM 308
           AEN+FV LKKDVDAAY+NKVELEAKV SL +EINF+  ++DAELSQ+QT V DTSVVLSM
Sbjct: 311 AENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSM 370

Query: 309 DNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIS 368
           DNNRNLDLDSIIAEV+AQYE+IA RS+AEAE+ YQTK ++LQ++  +HGD+L+NTK EI+
Sbjct: 371 DNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIA 430

Query: 369 EMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMA 428
           E+NRMIQRLRAEI+++KKQC +LQ ++ADAEQRGE ALKDA +K V+LE ALQ+AK+++A
Sbjct: 431 ELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELA 490

Query: 429 RLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYGSGSS 488
           R+LREYQELM++KLALD+EIATYRKLLEGEE R+SGE  S V+ISVV+ + S+G  SG  
Sbjct: 491 RMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISG-- 548

Query: 489 IGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSSVKFVSTTSSSQK 547
                 GLG GSG+  ++  G   G+G G  G        + GS SS K +STT+ +++
Sbjct: 549 ------GLGSGSGFGLSSGFGSGSGSGFGFGG-------SVSGSSSS-KIISTTTLNKR 593


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  613 bits (1580), Expect = e-175
 Identities = 362/630 (57%), Positives = 432/630 (68%), Gaps = 88/630 (13%)

Query: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR 60
           MSRQ+S T   GS+ GFS  SA+   +G SR S V+ +   AG G  G  S AG  FGSR
Sbjct: 1   MSRQASKTSGGGSQ-GFSGRSAVV--SGSSRMSCVAHS-GGAGGGAYGFRSGAGG-FGSR 55

Query: 61  SLYNLGGAKRVSIN--------------------------GCGSSCRSGFGGRASNRFGV 94
           SLYNLGG K +SI+                          G GS    GFGG      G+
Sbjct: 56  SLYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGM 115

Query: 95  NSGFGYGGGVGG--------------------GFSGPSFPVCP--------PGGIQEVTV 126
             GFG  GG GG                    GF GP     P        PGGIQEVT+
Sbjct: 116 GGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTI 175

Query: 127 NQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQE 186
           NQSLL PL+++IDP I +V+A+EREQIKTLNNKFASFIDKVRFLEQQNKVLETKW LLQ+
Sbjct: 176 NQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQ 235

Query: 187 QGSRTVR--QNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEIN 244
           QG+ ++    NLEPLF+++ + LR  L++I  ERGRL++EL+NM+D+VEDFK +YEDEIN
Sbjct: 236 QGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEIN 295

Query: 245 KRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSV 304
           KRTAAENEFV LKKDVD+AYMNKVEL+AKV +L +EI+F+ +++DAELSQ+Q+ + DTSV
Sbjct: 296 KRTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSV 355

Query: 305 VLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTK 364
           VLSMDNNR+LDLDSIIAEV+AQYEDIA RS+AEAE+ YQTK  ELQ TAGRHGDDLRNTK
Sbjct: 356 VLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTK 415

Query: 365 QEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAK 424
            EI E+NRMIQRLRAEI+ VKKQ ++LQTAIA+AEQ GE+ALKDA AKL +L+ ALQ+AK
Sbjct: 416 SEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAK 475

Query: 425 QDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSS--- 481
            D+ARLLR+YQELMN+KLALDVEIATYRKLLEGEE R+SGE  S V+ISVV+S+ +S   
Sbjct: 476 DDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASA 535

Query: 482 -----GYGSGSSIG-GGNLGLGGGSGYSFTTSGGHSLGAGLGG--SGFSATSNRG----- 528
                GYG G   G GG    GGGSG  F   GG  +G G GG  SGFS  S  G     
Sbjct: 536 GGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGA 595

Query: 529 ----LGGS-------GSSVKFVSTTSSSQK 547
                GG        G S+KF  ++ SSQ+
Sbjct: 596 RYGVSGGGFSSASNRGGSIKFSQSSQSSQR 625


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  608 bits (1569), Expect = e-174
 Identities = 354/589 (60%), Positives = 421/589 (71%), Gaps = 48/589 (8%)

Query: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR 60
           M+RQ      SG  +GFS  SA+   +G SR S V  ARS    GG     S   SFGSR
Sbjct: 1   MNRQVCKKSFSGRSQGFSGRSAVV--SGSSRMSCV--ARSGGAGGGACGFRSGAGSFGSR 56

Query: 61  SLYNLGGAKRVSIN-GCGSSCRSGFGG-RASNRF--------------------GVNSGF 98
           SLYNLG  K +SI+   GSS   GFGG R+S  F                    GV SGF
Sbjct: 57  SLYNLGSNKSISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGF 116

Query: 99  GYGGGVGG--GFSGPSFPVCP--------------PGGIQEVTVNQSLLTPLHLQIDPTI 142
           G  GG GG  GF GP     P              PGGIQEV VNQSLL PL+++IDP I
Sbjct: 117 GGAGGFGGAGGFGGPGVFGGPGSFGGPGGFGPGGFPGGIQEVIVNQSLLQPLNVEIDPQI 176

Query: 143 QRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDS 202
            +V+A+EREQIKTLNNKFASFIDKVRFLEQQNKVLETKW LLQ+Q + +   +LEP F+S
Sbjct: 177 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFES 236

Query: 203 YTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDA 262
           Y S L +QL+S+  ERG LE EL++MQD+VEDFK +YEDEINKRTAAENEFV LKKDVDA
Sbjct: 237 YISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDA 296

Query: 263 AYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAE 322
           A+MNKVEL+AKV SL +E++F+ ++++ ELSQ+Q+   DTSVVLSMDNNR LDL SIIAE
Sbjct: 297 AFMNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAE 356

Query: 323 VKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEID 382
           V+AQYE+IA RS++EAE+ YQTK  ELQ TAGRHGDDLRNTK EI E+NRMIQRLRAEI+
Sbjct: 357 VRAQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIE 416

Query: 383 SVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKL 442
           +VKKQ ++LQTAIA+AEQRGE+ALKDA AKL DL+ ALQKAK D+ARLLR+YQELMN+KL
Sbjct: 417 NVKKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKL 476

Query: 443 ALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYGSGSSIG--GGNLGLGGG- 499
           ALDVEIATYRKLLEGEECR+SGE  S V ISVV++  S+   SGSS G  GG  G G G 
Sbjct: 477 ALDVEIATYRKLLEGEECRMSGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGG 536

Query: 500 --SGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSSVKFVSTTSSSQ 546
              G S ++S G+ +  G  GSG+   S+   GG GSS  + S++S S+
Sbjct: 537 YKGGSSSSSSSGYGVSGG-SGSGYGGVSSGSTGGRGSSGSYQSSSSGSR 584


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  600 bits (1546), Expect = e-171
 Identities = 336/551 (60%), Positives = 410/551 (74%), Gaps = 25/551 (4%)

Query: 4   QSSITFQSGSRRG-FSTTSAITPAAGRSR--FSSVSVARSAAGSGGLGRISSAGASFGSR 60
           +SS++ Q+ S +G FS+ SA   +  ++R  FSSV+V+RS +GSGG          FGSR
Sbjct: 2   RSSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRS-SGSGGGAHCGPGTGGFGSR 60

Query: 61  SLYNLGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGG 120
           SLYNLGG K +S++  G +      GRA   FG  S    G G G    GP+   CPPGG
Sbjct: 61  SLYNLGGHKSISVSVAGGALL----GRALGGFGFGSRAFMGQGAGRQTFGPA---CPPGG 113

Query: 121 IQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETK 180
           IQEVTVNQSLLTPLH++IDP IQRVR +EREQIKTLNNKFASFIDKVRFLEQQNKVLETK
Sbjct: 114 IQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETK 173

Query: 181 WALLQEQGSR--TVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVR 238
           WALLQEQG      R NLEPLF++Y   +R  L+ + +ERGRL++ELRN+QD+VEDFK +
Sbjct: 174 WALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNK 233

Query: 239 YEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQ 298
           YEDEINK TAAENEFV LKKDVDAAYM +++L  KV +L +EI+F+  +++ ELSQ+QT 
Sbjct: 234 YEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTH 293

Query: 299 VGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGD 358
           V +T+VVLSMDNNRNLDLDSIIAEVKAQYE IA RSRAEAE+WYQTKYEELQVTAG+HGD
Sbjct: 294 VSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGD 353

Query: 359 DLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEE 418
           +LR+TK EI+E+ R IQRL+ E D+ KKQC  LQTAIA+AEQRGELALKDA+ KL DL+ 
Sbjct: 354 NLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDV 413

Query: 419 ALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTST 478
           AL +AK+D+ RLLR+YQELMN+KLALDVEIATYRKLLE EE R+SGE  S V+IS VT  
Sbjct: 414 ALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSIS-VTGN 472

Query: 479 LSSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSSVKF 538
            ++  G G++  GG + LGG  G    T GG S   G       +T   G   +G+S+  
Sbjct: 473 STTVCGGGAASFGGGISLGGSGG---ATKGGFSTNVGY------STVKGGPVSAGTSILR 523

Query: 539 VSTT--SSSQK 547
            +TT  +SSQ+
Sbjct: 524 KTTTVKTSSQR 534


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  584 bits (1506), Expect = e-167
 Identities = 336/590 (56%), Positives = 416/590 (70%), Gaps = 62/590 (10%)

Query: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSG------GLGRISSAG 54
           MSRQ S      S  GFS+ SA      R R +S S  RS  G G      G G    AG
Sbjct: 1   MSRQFSSRSGYRSGGGFSSGSAGIINYQR-RTTSSSTRRSGGGGGRFSSCGGGGGSFGAG 59

Query: 55  ASFGSRSLYNLGGAKRVSIN---------------GCGSSCRSGFGGRASNRFGVNSG-- 97
             FGSRSL NLGG+K +SI+               G G     GFGG      G+  G  
Sbjct: 60  GGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGF 119

Query: 98  ---------FGYGGGVGGGFSGPSFPVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAE 148
                    FG GG  GGG+ G   PVCPPGGIQEVT+NQSLL PL+++IDP IQ+V++ 
Sbjct: 120 GGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSR 179

Query: 149 EREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELR 208
           EREQIK+LNN+FASFIDKVRFLEQQN+VL+TKW LLQ+  + T   NLEP F+S+ + LR
Sbjct: 180 EREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLR 239

Query: 209 RQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKV 268
           R+++ + +++ RL++EL+NMQD+VED++ +YEDEINKRT AENEFV +KKDVD AYM KV
Sbjct: 240 RRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKV 299

Query: 269 ELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYE 328
           +L+AK+ +L +EI+F+ +++ AELSQ+QTQ+ +T+V+LSMDNNR+LDLDSIIAEVKAQYE
Sbjct: 300 DLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYE 359

Query: 329 DIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQC 388
           DIA +S+AEAES YQ+KYEELQ+TAGRHGD +RN+K EISE+NR+IQRLR+EID+VKKQ 
Sbjct: 360 DIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQI 419

Query: 389 SSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEI 448
           S+LQ +I+DAEQRGE ALKDA+ KL DLE+ALQ+AK+D+ARLLR+YQELMN KLALD+EI
Sbjct: 420 SNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEI 479

Query: 449 ATYRKLLEGEECRLSGEGVSPVNISVVTS--TLS---------SGYGSGSS---IGGGNL 494
           ATYR LLEGEE R+SGE    V++SV TS  T+S          GYGSG S    GGG+ 
Sbjct: 480 ATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSY 539

Query: 495 GLGG---------GSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSS 535
           G GG         GSG S   SGG S G+G GG G       G  GSGSS
Sbjct: 540 GSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGG------HGSYGSGSS 583


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  575 bits (1483), Expect = e-164
 Identities = 323/554 (58%), Positives = 388/554 (70%), Gaps = 41/554 (7%)

Query: 12  GSRRGFSTTSAITPAAGRSRFSSVS-VARSAAGSGGLGRISSAGASFGSRSLYNLGGAKR 70
           G  RGFS+ SA+     R   SS S ++R   G GG G     G  FGSRSL  LGG K 
Sbjct: 17  GGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFG-----GGGFGSRSLVGLGGTKS 71

Query: 71  VSIN----GCGSSCRSGFGGRAS-----NRFGVNSGF--------GYGGGVGGGFSGPSF 113
           +SI+    G G     GFGGR       + FG  SGF        G+GGG  GGF GP  
Sbjct: 72  ISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGG 131

Query: 114 -----------PVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFAS 162
                      P   PGGI EV+VNQSLL PL++++DP IQ V+A+EREQIKTLNNKFAS
Sbjct: 132 VGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFAS 191

Query: 163 FIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLE 222
           FIDKVRFLEQQN+VL+TKW LLQ+    T   NLEP+F  Y   L+R L+ +T ER    
Sbjct: 192 FIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQN 251

Query: 223 AELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEIN 282
           +EL NMQD+VED+K +YEDEINKRTAAEN+FV LKKDVD AYM KVEL++KV  L +EI 
Sbjct: 252 SELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIE 311

Query: 283 FIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWY 342
           F+  ++DAE+SQ+   V DT+V+LSMDN+RNLDLDSIIAEVKAQYE+IA RS+ EAE+ Y
Sbjct: 312 FLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALY 371

Query: 343 QTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRG 402
            +KYEELQVT GRHGD L+  K EISE+NR+IQRL+ EI  VKKQC ++Q AIADAEQRG
Sbjct: 372 HSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRG 431

Query: 403 ELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRL 462
           E ALKDAR KL DLEEALQ+AK+D+ARLLR+YQELMN+KLALDVEIATYRKLLEGEECR+
Sbjct: 432 EHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRM 491

Query: 463 SGEGVSPVNISVVTSTLSSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFS 522
           SG+  S V +SV +ST+SS   S ++ GG   G G  SG      GG+S G+   GSG  
Sbjct: 492 SGDLSSNVTVSVTSSTISSNVASKAAFGGSG-GRGSSSG------GGYSSGSSSYGSGGR 544

Query: 523 ATSNRGLGGSGSSV 536
            + +RG  G G S+
Sbjct: 545 QSGSRGGSGGGGSI 558



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 44/114 (38%), Positives = 56/114 (49%), Gaps = 20/114 (17%)

Query: 11  SGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAG--ASFGSRSLYNLGG- 67
           S S  G+S+ S+   + GR        + S  GSGG G IS  G  +  GS   Y  GG 
Sbjct: 526 SSSGGGYSSGSSSYGSGGRQ-------SGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGG 578

Query: 68  AKRVSINGCGSSCRSGFGGRAS---NRFGVNSGFGYGGGVGG-----GFSGPSF 113
           +K  SI+G G    SG G  +S   +R G +SG GYG G GG     G SG +F
Sbjct: 579 SKGGSISGGGYG--SGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEAF 630


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  575 bits (1481), Expect = e-164
 Identities = 318/578 (55%), Positives = 402/578 (69%), Gaps = 34/578 (5%)

Query: 1   MSRQ--SSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFG 58
           MS Q  S   F S SRR +ST+S+     G     SV  AR   G GG G     G  FG
Sbjct: 1   MSHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYG---IHGRGFG 57

Query: 59  SRSLYNLGGAKRVSINGCGSS----CRSG-FGGRASNR-FGVNS----GFGYGGGVGGGF 108
           SRSLYNLGG++ +SIN  G S    C+ G  GG    R FGV S    GFG GG  G GF
Sbjct: 58  SRSLYNLGGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGF 117

Query: 109 SGPSF------PVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFAS 162
              +F      P CPPGGIQEVT+NQSLL PLHL++DP IQR++ +EREQI  LNNKFAS
Sbjct: 118 GTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFAS 177

Query: 163 FIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLE 222
           FIDKVRFLEQQN+VL+TKW LLQ+  + T   NLEPL ++Y  +LRRQ++ ++ E+ R  
Sbjct: 178 FIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQN 237

Query: 223 AELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEIN 282
           AE+R+MQDVVED+K +YEDEINKRT +EN+FV LKKDVDAAY++KV+LE++V +L  E+N
Sbjct: 238 AEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVN 297

Query: 283 FIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWY 342
           F+  +F  ELSQ+QT + DT+V+LSMDNNR+LDLDSII  V+ QYE IA RS+ EAE+ Y
Sbjct: 298 FLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALY 357

Query: 343 QTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRG 402
           QTKY+ELQ+TAGRHGDDL+N+K EI+E+NR +QRL+AEI +VKKQ   +Q+ I+DAE+RG
Sbjct: 358 QTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERG 417

Query: 403 ELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRL 462
           E AL+DA  KL DLEEALQ++K+++ARLLR+YQ ++ +KL+LDVEIATYR+LLEGEE R+
Sbjct: 418 EQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRM 477

Query: 463 SGEGVSPVNISVVTSTLS--SGYGSGSSIGGGNLGLGGGSGYSFTTS-----------GG 509
           SGE  S V+ISV  S +S   G G G S G G  G G G GY    S           GG
Sbjct: 478 SGELQSHVSISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGG 537

Query: 510 HSLGAGLGGSGFSATSNRGLGGSGSSVKFVSTTSSSQK 547
           +  G G GG  +  +   G G S   +   ST +S ++
Sbjct: 538 YGSGCGGGGGSYGGSGRSGRGSSRVQIIQTSTNTSHRR 575


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  563 bits (1450), Expect = e-160
 Identities = 316/552 (57%), Positives = 404/552 (73%), Gaps = 38/552 (6%)

Query: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR 60
           MSRQ +    + ++ GFS  SA+      S F         AGS GL         FGSR
Sbjct: 1   MSRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFR--------AGSKGLS------GGFGSR 46

Query: 61  SLYNLGGAKRVSI-NGCGSSCRSGFG-GRASNRFGVNSGFGYGGGVGGGFS-GPSFP-VC 116
           SLY+LGG + +++ +G G S   GFG GRAS         G+ G + G  + GP  P VC
Sbjct: 47  SLYSLGGVRSLNVASGSGKSGGYGFGRGRAS---------GFAGSMFGSVALGPVCPTVC 97

Query: 117 PPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKV 176
           PPGGI +VTVN+SLL PL++++DP IQ+VRA+EREQIK LNNKFASFIDKVRFLEQQN+V
Sbjct: 98  PPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQV 157

Query: 177 LETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFK 236
           LETKW LLQ+      + NLEP+ + Y S LR+QLE+++ +R RL++ELRN++DVVED+K
Sbjct: 158 LETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYK 217

Query: 237 VRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQ 296
            RYE+EINKRTAAENEFV LKKDVDAAY NKVEL+AKV+S+ +EI F   +F+AE++Q+Q
Sbjct: 218 KRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQ 277

Query: 297 TQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRH 356
           + + D SV+LSMDNNRNLDLDSII EV+ QYE+IA +S+AEAE+ YQTK++ELQ+ AGRH
Sbjct: 278 SHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRH 337

Query: 357 GDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDL 416
           GDDL+NTK EISE+ R+IQR+R+EI++VKKQ S+L+TAIADAEQRG+ ALKDARAKL +L
Sbjct: 338 GDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDEL 397

Query: 417 EEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVT 476
           E AL +AK+++AR+LREYQELM++KLALD+EIATYRKLLE EECR+SGE  SPV+IS+++
Sbjct: 398 EGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISIIS 457

Query: 477 STLSSGYGSGSSIGGGNLGLGGGSGY----SFTTSGGHSLGAGLGGSGFSATSNRGLGGS 532
           ST      SG S+ G    +  G GY    S   SG  S+  G G S  SA   +   G 
Sbjct: 458 ST------SGGSVYGFRPSMVSG-GYVANSSNCISGVCSVRGGEGRSRGSANDYKDTLGK 510

Query: 533 GSSVKFVSTTSS 544
           GSS+   S  +S
Sbjct: 511 GSSLSAPSKKTS 522


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score =  559 bits (1440), Expect = e-159
 Identities = 299/550 (54%), Positives = 398/550 (72%), Gaps = 41/550 (7%)

Query: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR 60
           MSRQ +    + ++ GFS  SA+      S +         AG  GL         F SR
Sbjct: 1   MSRQFTYKSGAAAKGGFSGCSAVLSGGSSSSYR--------AGGKGLS------GGFSSR 46

Query: 61  SLYNLGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSF------- 113
           SLY+LGGA+ +S N    S   G+ G          G+G+G G   GF+G  F       
Sbjct: 47  SLYSLGGARSISFNVASGS---GWAG----------GYGFGRGRASGFAGSMFGSVALGS 93

Query: 114 ---PVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFL 170
               +CPPGGI +VT+N+SLL PL++++DP IQ+VRA+EREQIK LNNKFASFIDKVRFL
Sbjct: 94  VCPSLCPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFL 153

Query: 171 EQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQD 230
           EQQN+VLETKW LLQ+      + NLEP+ + Y S LR+QLE+++ +R RL++ELR++++
Sbjct: 154 EQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRSVRE 213

Query: 231 VVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDA 290
           VVED+K RYE+EINKRT AENEFV LKKDVDAAY +KVEL+AKV +L  EI F   +++ 
Sbjct: 214 VVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEG 273

Query: 291 ELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQ 350
           E +Q+Q+ + DTS++LSMDNNRNLDLDSIIAEV+AQYE+IA +S+AEAE+ YQTK++ELQ
Sbjct: 274 ETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQ 333

Query: 351 VTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDAR 410
           + AGRHGDDL++TK EISE+ R+IQRLR+EI+SVKKQC++L+TAIADAEQRG+ ALKDAR
Sbjct: 334 LAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALKDAR 393

Query: 411 AKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPV 470
           AKL +LE ALQ+AK+++AR+LREYQEL+++KL+LD+EIATYRKLLEGEECR+SGE  + V
Sbjct: 394 AKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSV 453

Query: 471 NISVVTSTLSSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSL--GAGLGGSGFSATSNRG 528
           +ISV+ S+++   G+G+  G  N G  G   +  + SGG+S+  G  + GSG  +     
Sbjct: 454 SISVINSSMAGMAGTGAGFGFSNAGTYG--YWPSSVSGGYSMLPGGCVTGSGNCSPRGEA 511

Query: 529 LGGSGSSVKF 538
               GS+ +F
Sbjct: 512 RTRLGSASEF 521


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  551 bits (1421), Expect = e-157
 Identities = 303/542 (55%), Positives = 389/542 (71%), Gaps = 31/542 (5%)

Query: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR 60
           MSRQ +I   SG +  FS  SA+ P       +S      AAG G       AGA FGSR
Sbjct: 1   MSRQLNIK-SSGDKGNFSVHSAVVPRKAVGSLASYC----AAGRG-------AGAGFGSR 48

Query: 61  SLYNLGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSF------- 113
           SLY+LGG +R+S N  G   R+G        +G   G GYGGG   GF+G  F       
Sbjct: 49  SLYSLGGNRRISFNVAGGGVRAG-------GYGFRPGSGYGGGRASGFAGSMFGSVALGP 101

Query: 114 ---PVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFL 170
               VCPPGGI +VTVN+SLL PL++++DP IQ+VRA+EREQIK LN+KFASFIDKVRFL
Sbjct: 102 ACLSVCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFL 161

Query: 171 EQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQD 230
           EQQN+VLETKW LLQ+      ++NLEP+ + Y S LR+QLE+++ +R RL++ELR+M+D
Sbjct: 162 EQQNQVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRD 221

Query: 231 VVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDA 290
           +VED+K RYE EIN+RT AENEFV LKKD DAAY  KVEL+AKV SL +EI F+  ++DA
Sbjct: 222 LVEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDA 281

Query: 291 ELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQ 350
           E++Q+QT   +TSV+LSMDNNR+LDLDSIIAEV+  YE+IA +S+AEAE+ YQTK +ELQ
Sbjct: 282 EIAQIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQ 341

Query: 351 VTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDAR 410
           + A RHGDDL++T+ E+ E+NR+IQR+R EI +VKKQ +SL+TAIADAEQRG+ ALKDA+
Sbjct: 342 LAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQ 401

Query: 411 AKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPV 470
           AKL +LE AL +AK+++AR+LREYQELM++KLALD+EIATYRKLLEGEECR+SGE  S V
Sbjct: 402 AKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSV 461

Query: 471 NISVVTSTLSSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLG 530
           +ISV++S+ S  Y   SS  G +LG    +G S +T  G +      G     T  +   
Sbjct: 462 SISVISSS-SYSYHHPSS-AGVDLGASAVAGSSGSTQSGQTKTTEARGGDLKDTQGKSTP 519

Query: 531 GS 532
            S
Sbjct: 520 AS 521


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  548 bits (1413), Expect = e-156
 Identities = 308/538 (57%), Positives = 395/538 (73%), Gaps = 31/538 (5%)

Query: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR 60
           MSRQ +  F  G R GFS  SA+   +G    SS S      GS          ASFGS+
Sbjct: 1   MSRQLT-HFPRGERLGFSGCSAVL--SGGIGSSSASFRARVKGS----------ASFGSK 47

Query: 61  SLYNLGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFP-VCPPG 119
           SL  LGG++ ++++   ++ R G GGR     G  + FG  G       GP  P VCPPG
Sbjct: 48  SLSCLGGSRSLALS---AAARRG-GGRLGGFVG--TAFGSAG------LGPKCPSVCPPG 95

Query: 120 GIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLET 179
           GI +VTVN+SLL PL++++DP IQRVRA+EREQIK LNNKFASFIDKVRFLEQQN+VLET
Sbjct: 96  GIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLET 155

Query: 180 KWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRY 239
           KW LLQ+      R+NLEP+++ Y S L++QLE ++ +  RL++ELRNMQD+VED+K RY
Sbjct: 156 KWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRY 215

Query: 240 EDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQV 299
           E EIN+RTAAENEFV LKKDVDAAYMNKVEL+AKV SL +EI F   +++ E++Q+Q+ +
Sbjct: 216 EVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHI 275

Query: 300 GDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDD 359
            DTS+VLSMDNNR+LDLDSIIAEV+AQYE+IA +S+AEAE+ YQTK +ELQVTAG+HGDD
Sbjct: 276 SDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDD 335

Query: 360 LRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEA 419
           L+ TK EISE+NR+IQR+R+EI +VKKQC+ L+TAIADAEQRG+ ALKDARAKL +LE A
Sbjct: 336 LKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGA 395

Query: 420 LQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTL 479
           L +AK+++AR+LREYQEL+++KLALD+EIATYRKLLE EECR+SGE  + V+ISV++ST 
Sbjct: 396 LHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTN 455

Query: 480 SSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSSVK 537
           +   G+G S     +G G  S YS+ T+       G  GS       +  G S ++ K
Sbjct: 456 AGAGGAGFS-----MGFGASSSYSYKTAAADVKTKGSCGSELKDPLAKTSGSSCATKK 508


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  548 bits (1413), Expect = e-156
 Identities = 308/538 (57%), Positives = 395/538 (73%), Gaps = 31/538 (5%)

Query: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR 60
           MSRQ +  F  G R GFS  SA+   +G    SS S      GS          ASFGS+
Sbjct: 1   MSRQLT-HFPRGERLGFSGCSAVL--SGGIGSSSASFRARVKGS----------ASFGSK 47

Query: 61  SLYNLGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFP-VCPPG 119
           SL  LGG++ ++++   ++ R G GGR     G  + FG  G       GP  P VCPPG
Sbjct: 48  SLSCLGGSRSLALS---AAARRG-GGRLGGFVG--TAFGSAG------LGPKCPSVCPPG 95

Query: 120 GIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLET 179
           GI +VTVN+SLL PL++++DP IQRVRA+EREQIK LNNKFASFIDKVRFLEQQN+VLET
Sbjct: 96  GIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLET 155

Query: 180 KWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRY 239
           KW LLQ+      R+NLEP+++ Y S L++QLE ++ +  RL++ELRNMQD+VED+K RY
Sbjct: 156 KWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRY 215

Query: 240 EDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQV 299
           E EIN+RTAAENEFV LKKDVDAAYMNKVEL+AKV SL +EI F   +++ E++Q+Q+ +
Sbjct: 216 EVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHI 275

Query: 300 GDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDD 359
            DTS+VLSMDNNR+LDLDSIIAEV+AQYE+IA +S+AEAE+ YQTK +ELQVTAG+HGDD
Sbjct: 276 SDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDD 335

Query: 360 LRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEA 419
           L+ TK EISE+NR+IQR+R+EI +VKKQC+ L+TAIADAEQRG+ ALKDARAKL +LE A
Sbjct: 336 LKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGA 395

Query: 420 LQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTL 479
           L +AK+++AR+LREYQEL+++KLALD+EIATYRKLLE EECR+SGE  + V+ISV++ST 
Sbjct: 396 LHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTN 455

Query: 480 SSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSSVK 537
           +   G+G S     +G G  S YS+ T+       G  GS       +  G S ++ K
Sbjct: 456 AGAGGAGFS-----MGFGASSSYSYKTAAADVKTKGSCGSELKDPLAKTSGSSCATKK 508


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  523 bits (1346), Expect = e-148
 Identities = 299/487 (61%), Positives = 355/487 (72%), Gaps = 49/487 (10%)

Query: 33  SSVSVARSAA--GSGGLGRISSAG-ASFGSRSLYNLGGAK-RVSINGCGSSCRSGFGGRA 88
           S V  +RSAA  G G   R+SSA     GS SLY LG ++ RV++               
Sbjct: 7   SPVFTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSA------------ 54

Query: 89  SNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAE 148
                      YGG VG G             I+EVT+NQSLL PL L  DP++QRVR E
Sbjct: 55  -----------YGGPVGAG-------------IREVTINQSLLAPLRLDADPSLQRVRQE 90

Query: 149 EREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELR 208
           E EQIKTLNNKFASFIDKVRFLEQQNK+LETKW LLQEQ S      L  +F++  + LR
Sbjct: 91  ESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAK-SSRLPDIFEAQIAGLR 149

Query: 209 RQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKV 268
            QLE++  + GRLEAELR+MQDVVEDFK +YEDEIN RTAAENEFV LKKDVDAAYM+KV
Sbjct: 150 GQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMSKV 209

Query: 269 ELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYE 328
           ELEAKV +L +EINF+ ++ + EL++LQ+Q+ DTSVVLSMDN+R+LDLD IIAEVKAQYE
Sbjct: 210 ELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYE 269

Query: 329 DIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQC 388
           ++A  SRAEAE+WYQTK+E LQ  AG+HGDDLRNT+ EISEMNR IQRL+AEID++K Q 
Sbjct: 270 EMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQR 329

Query: 389 SSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEI 448
           + L+ AIA+AE+RGELALKDARAK  +LE ALQ+ KQDMAR LREYQELM++KLALD+EI
Sbjct: 330 AKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDIEI 389

Query: 449 ATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYGSGSSIGGGNLGLGGGSG---YSFT 505
           ATYRKLLEGEE RL+G+GV  VNISV+ ST     G  SS GG  L LGG  G    SF+
Sbjct: 390 ATYRKLLEGEESRLAGDGVGAVNISVMNST-----GGSSSGGGIGLTLGGTMGSNALSFS 444

Query: 506 TSGGHSL 512
           +S G  L
Sbjct: 445 SSAGPGL 451


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  522 bits (1344), Expect = e-148
 Identities = 287/449 (63%), Positives = 345/449 (76%), Gaps = 16/449 (3%)

Query: 79  SCRSGFGGR-ASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEVTVNQSLLTPLHLQ 137
           S  SG G R +S+ F       + GG+GGG+ G S      GGI  VTVNQSLL+PL L+
Sbjct: 24  SYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGAS----GMGGITAVTVNQSLLSPLVLE 79

Query: 138 IDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLE 197
           +DP IQ VR +E+EQIKTLNNKFASFIDKVRFLEQQNK+LETKW+LLQ+Q  +T R N++
Sbjct: 80  VDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQ--KTARSNMD 137

Query: 198 PLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVALK 257
            +F+SY + LRRQLE++  E+ +LEAEL NMQ +VEDFK +YEDEINKRT  ENEFV +K
Sbjct: 138 NMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIK 197

Query: 258 KDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLD 317
           KDVD AYMNKVELE++++ L +EINF+  +++ E+ +LQ+Q+ DTSVVLSMDN+R+LD+D
Sbjct: 198 KDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDNSRSLDMD 257

Query: 318 SIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRL 377
           SIIAEVKAQYEDIANRSRAEAES YQ KYEELQ  AG+HGDDLR TK EISEMNR I RL
Sbjct: 258 SIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRL 317

Query: 378 RAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREYQEL 437
           +AEI+ +K Q +SL+ AIADAEQRGELA+KDA AKL +LE ALQ+AKQDMAR LREYQEL
Sbjct: 318 QAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLREYQEL 377

Query: 438 MNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYGSGSSIGGGNLGLG 497
           MN+KLALD+EIATYRKLLEGEE RL        N+S+ T T +SGY  G S   G L   
Sbjct: 378 MNVKLALDIEIATYRKLLEGEESRLES---GMQNMSIHTKT-TSGYAGGLSSAYGGL-TS 432

Query: 498 GGSGYSFTTSGGHSLGAGLGGSGFSATSN 526
            G  YS     G S G+G G S FS TS+
Sbjct: 433 PGLSYSL----GSSFGSGAGSSSFSRTSS 457


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  509 bits (1310), Expect = e-144
 Identities = 312/613 (50%), Positives = 391/613 (63%), Gaps = 86/613 (14%)

Query: 6   SITFQSGSRRG-FSTTSAITPA-AGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLY 63
           S    SG R G FS+ SA+TP    R R +SVS   S  G  GLG       SFGSRS+ 
Sbjct: 5   SYRVSSGHRVGNFSSCSAMTPQNLNRFRANSVS-CWSGPGFRGLG-------SFGSRSVI 56

Query: 64  NLGG-AKRVSINGC---------GSSCRSGFGGRASNRFG------VNSGFGYGGGVGGG 107
             G  + R++  G          G+ C  GFG       G      V  GFG G G+G G
Sbjct: 57  TFGSYSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYG 116

Query: 108 FSGPSF---------PVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNN 158
           F GP F         P  P   I  VTVN+SLLTPL+L+IDP  QRV+ +E+EQIKTLNN
Sbjct: 117 FGGPGFGYRVGGVGVPAAP--SITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNN 174

Query: 159 KFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTER 218
           KFASFIDKVRFLEQQNK+LETKW+ LQEQ  + +R NLEPLF+SY + LRRQLE + +++
Sbjct: 175 KFASFIDKVRFLEQQNKLLETKWSFLQEQ--KCIRSNLEPLFESYITNLRRQLEVLVSDQ 232

Query: 219 GRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLP 278
            RL+AE  ++QDV+E FK +YE+E+  R  AENEFVALKKDVDAA+MNK +LEA V +L 
Sbjct: 233 ARLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLT 292

Query: 279 EEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEA 338
           +EI+F+ +++  E+  LQ+ + +TSV++ MDN+R+L+LD IIAEVKAQYE++A RSRA+A
Sbjct: 293 QEIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADA 352

Query: 339 ESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADA 398
           E+WYQTKYEE+QVTAG+H D+LRN + EI+E+ R+IQRL+AEI+  K Q + L+ A+A+A
Sbjct: 353 EAWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEA 412

Query: 399 EQRGELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGE 458
           EQ+GE  L DA+ KL DLE ALQ+AKQDMAR L EYQELMN KL LD+EIATYR+LLEGE
Sbjct: 413 EQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGE 472

Query: 459 ECRLSGEGVSPVNISVVTSTLSSGYGSGSSIGGGNLGLGG----GSGYSFTTSGG-HSLG 513
           E RL  EGV PVNISV +S      G    + G  L  GG    GS     TSG   S G
Sbjct: 473 ESRLC-EGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCG 531

Query: 514 AGLGGS-------------------------------------GFSATSNRGLGGSGSSV 536
             LGG+                                     GFS+ S    GG  SSV
Sbjct: 532 PSLGGARVAPATGDLLSTGTRSGSMLISEACVPSVPCPLPTQGGFSSCS----GGRSSSV 587

Query: 537 KFVSTTSSSQKSY 549
           +FVSTT+S +  Y
Sbjct: 588 RFVSTTTSCRTKY 600


>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score =  473 bits (1217), Expect = e-133
 Identities = 273/536 (50%), Positives = 360/536 (67%), Gaps = 30/536 (5%)

Query: 22  AITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLYNLGGAKRVSINGCGSSCR 81
           +++P   +  FS+ S   + +     G  SS G  F SRSL + GG    S    GS+  
Sbjct: 2   SLSPCRAQRGFSARSACSARSRGRSRGGFSSRGG-FSSRSLNSFGGCLEGSR---GSTW- 56

Query: 82  SGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEVTVNQSLLTPLHLQIDPT 141
            G GGR   RFG  SG            GP   +CPPGGIQEVT+NQ+LLTPL ++IDP 
Sbjct: 57  -GSGGRLGVRFGEWSG------------GPGLSLCPPGGIQEVTINQNLLTPLKIEIDPQ 103

Query: 142 IQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFD 201
            Q VR +E ++I+TLNN+FASFIDKVRFLEQQNKVLETKW LLQ+QG    +Q LEP+F+
Sbjct: 104 FQVVRTQETQEIRTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFE 163

Query: 202 SYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVD 261
           +   +LR+QLE +  ERG L+AEL+  +D  E++K +YE+E ++R   EN+FV LKKDVD
Sbjct: 164 ACLDQLRKQLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVD 223

Query: 262 AAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIA 321
             +++K+ELE K+++L E + F+  + + EL QLQTQ  DTSVVLSMDNNR LD  SII 
Sbjct: 224 GVFLSKMELEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIIT 283

Query: 322 EVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEI 381
           EV+A+YE+IA  S+AEAE+ YQTKY+ELQV+A  HGD ++ TK +IS++++ IQRL+++ 
Sbjct: 284 EVRARYEEIARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQT 343

Query: 382 DSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIK 441
           +++KKQ +SLQ AI DAEQRGELALKDA+AK+ +LE AL+ AKQ++ARLL EYQEL + K
Sbjct: 344 ENLKKQNASLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTK 403

Query: 442 LALDVEIATYRKLLEGEECRLSGEGVSPVNISVV--TSTLSSGYGSGSSIGGGNLGLGGG 499
           L+LDVEIATYR+LLEGEECR+SGE  S V IS V  ++ +S G G G    G   GLG G
Sbjct: 404 LSLDVEIATYRRLLEGEECRMSGECTSQVTISSVGGSAVMSGGVGGGL---GSTCGLGSG 460

Query: 500 SG------YSFTTSGGH-SLGAGLGGSGFSATSNRGLGGSGSSVKFVSTTSSSQKS 548
            G       S  T G +  LG+G      S + +    GS        T  SS K+
Sbjct: 461 KGSPGSCCTSIVTGGSNIILGSGKDPVLDSCSVSGSSAGSSCHTILKKTVESSLKT 516


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  468 bits (1204), Expect = e-132
 Identities = 278/538 (51%), Positives = 357/538 (66%), Gaps = 73/538 (13%)

Query: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR 60
           MSRQ +  F  G R GFS  SA+   +G    SS S      GS          ASFGS+
Sbjct: 1   MSRQLT-HFPRGERLGFSGCSAVL--SGGIGSSSASFRARVKGS----------ASFGSK 47

Query: 61  SLYNLGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFP-VCPPG 119
           SL  LGG++ ++++   ++ R G GGR     G  + FG  G       GP  P VCPPG
Sbjct: 48  SLSCLGGSRSLALS---AAARRG-GGRLGGFVG--TAFGSAG------LGPKCPSVCPPG 95

Query: 120 GIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLET 179
           GI +VTVN+SLL PL++++DP IQRVRA+EREQIK LNNKFASFIDKVRFLEQQN+VLET
Sbjct: 96  GIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLET 155

Query: 180 KWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRY 239
           KW LLQ+      R+NLEP+++ Y S L++QLE ++ +  RL++ELRNMQD+VED+K RY
Sbjct: 156 KWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRY 215

Query: 240 EDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQV 299
           E EIN+RTAAENEFV LKKDVDAAYMNKVEL+AKV SL +EI F   +++ E++Q+Q+ +
Sbjct: 216 EVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHI 275

Query: 300 GDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDD 359
            DTS+VLSMDNNR+LDLDSIIAEV+AQYE+IA +S+AEAE+ YQTK              
Sbjct: 276 SDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTK-------------- 321

Query: 360 LRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEA 419
                                       C+ L+TAIADAEQRG+ ALKDARAKL +LE A
Sbjct: 322 ----------------------------CADLETAIADAEQRGDCALKDARAKLDELEGA 353

Query: 420 LQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTL 479
           L +AK+++AR+LREYQEL+++KLALD+EIATYRKLLE EECR+SGE  + V+ISV++ST 
Sbjct: 354 LHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTN 413

Query: 480 SSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSSVK 537
           +   G+G S     +G G  S YS+ T+       G  GS       +  G S ++ K
Sbjct: 414 AGAGGAGFS-----MGFGASSSYSYKTAAADVKTKGSCGSELKDPLAKTSGSSCATKK 466


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  453 bits (1166), Expect = e-127
 Identities = 264/523 (50%), Positives = 345/523 (65%), Gaps = 48/523 (9%)

Query: 3   RQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSL 62
           R   I+   G  R FS+ SA+ P  G     S +  R  +   GL         FGSRSL
Sbjct: 4   RSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGL-------TGFGSRSL 56

Query: 63  YNLGGA-KRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGI 121
            NLG    R+++ G     R+G  GR+         FGY  G   G  GPS P C    I
Sbjct: 57  CNLGSCGPRIAVGGF----RAGSCGRS---------FGYRSG---GVCGPS-PPC----I 95

Query: 122 QEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKW 181
             V+VN+SLLTPL+L+IDP  Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETKW
Sbjct: 96  TTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKW 155

Query: 182 ALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYED 241
              Q Q  R    NLEPLF  Y   LRR+ E +  + GRL +EL ++Q+V+E +K +YE+
Sbjct: 156 QFYQNQ--RCCESNLEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEE 213

Query: 242 EINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGD 301
           E+  R  AENEFV LKKDVD AY+ K +LEA V++L EE +F+  +++ E+  LQ  + D
Sbjct: 214 EVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISD 273

Query: 302 TSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLR 361
           TSV++ MDN+R+L++D IIAE+KAQY+D+A+RSRAEAESWY++K EE++ T  RHG+ LR
Sbjct: 274 TSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLR 333

Query: 362 NTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQ 421
            TK+EI+E+NRMIQRL AEI++ K Q + L+ A+A+AEQ+GE AL DAR KL +LE ALQ
Sbjct: 334 RTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQ 393

Query: 422 KAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSS 481
           KAKQDMA LL+EYQE+MN KL LD+EIATYR+LLEGEE RL  EGV  VN+ V       
Sbjct: 394 KAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLC-EGVGSVNVCV------- 445

Query: 482 GYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSAT 524
                SS GG + G     G S++T+ G  + +G    G S T
Sbjct: 446 ----SSSRGGVSCG-----GLSYSTTPGRQITSGPSAIGGSIT 479


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  451 bits (1161), Expect = e-127
 Identities = 268/540 (49%), Positives = 355/540 (65%), Gaps = 42/540 (7%)

Query: 8   TFQSGSRRG---FSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLYN 64
           +FQ GSR G   FS+ SA+ P       +  +V++     GG GR   A    GSRSL N
Sbjct: 5   SFQPGSRCGSQSFSSYSAVMPRM----VTHYAVSKGPCRPGG-GRGLRALGCLGSRSLCN 59

Query: 65  LGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEV 124
           +G  +    + CG               G   GFGY  G      GPS  + P      V
Sbjct: 60  VGFGRPRVASRCG---------------GTLPGFGYRLGAT---CGPSACITP------V 95

Query: 125 TVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALL 184
           T+N+SLL PL L+IDPT+QRV+ +E+EQIK LNN+FASFI+KVRFLEQ+NK+LETKW  +
Sbjct: 96  TINESLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFM 155

Query: 185 QEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEIN 244
           Q+Q  R  + N+EP+F+ Y S LRRQL+ ++ +R RLE+EL ++Q  +E +K +YE+E++
Sbjct: 156 QQQ--RCCQTNIEPIFEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELS 213

Query: 245 KRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSV 304
            R   ENEFVALKKDVD A++ K +LE   ++L +EI+F+ S+++ E+  LQ+Q+ +TSV
Sbjct: 214 LRPCVENEFVALKKDVDTAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSV 273

Query: 305 VLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTK 364
           ++ MDN+R LD+D IIAE+KAQY+DIA+RS+AEAE+WYQ +YEEL+VTAG H D+LRN K
Sbjct: 274 IVKMDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRK 333

Query: 365 QEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAK 424
            EI EMN++IQRL+ E ++VK Q   L+ AIA+AEQ+GE AL DA+ KL  LEEALQKAK
Sbjct: 334 NEILEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAK 393

Query: 425 QDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYG 484
           QDMA LL+EYQE+MN KL LD+EIATYR+LLEGEE RL  EG+ PVNISV +S  +  Y 
Sbjct: 394 QDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLC-EGIGPVNISVSSSKGAFLYE 452

Query: 485 ----SGSSIGGGNLGLGGGSGYSFTTS---GGHSLGAGLGGSGFSATSNRGLGGSGSSVK 537
               S   +  G L   GG     T          G    GSG  ++   G GGS  S K
Sbjct: 453 PCGVSTPVLSTGVLRSNGGCSIVGTGELYVPCEPQGLLSCGSGRKSSMTLGAGGSSPSHK 512


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  430 bits (1106), Expect = e-120
 Identities = 262/540 (48%), Positives = 343/540 (63%), Gaps = 63/540 (11%)

Query: 15  RGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLYNLGGAKRVSIN 74
           R FS  SA  P  GR   +       AA   G+         FGS S+            
Sbjct: 10  RAFSCISACGPRPGRCCIT-------AAPYRGISCYRGLTGGFGSHSV------------ 50

Query: 75  GCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEVTVNQSLLTPL 134
            CG   R+G  GR+         FGY  G   G  GPS P C    I  V+VN+SLLTPL
Sbjct: 51  -CGGF-RAGSCGRS---------FGYRSG---GVCGPS-PPC----ITTVSVNESLLTPL 91

Query: 135 HLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQ 194
           +L+IDP  Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +     + 
Sbjct: 92  NLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQS 149

Query: 195 NLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFV 254
           NLEPLF+ Y   LRR+ E +  + GRL +EL ++Q+V+E +K +YE+E++ R  AENEFV
Sbjct: 150 NLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFV 209

Query: 255 ALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNL 314
           ALKKDVD AY+ K +LEA V++L +EI+F+  +++ E+  LQ+ + DTSVV+ +DN+R+L
Sbjct: 210 ALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDL 269

Query: 315 DLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMI 374
           ++D IIAE+KAQY+DI  RSRAEAESWY++K EE++ T  RHG+ LR TK+EI+E+NRMI
Sbjct: 270 NMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMI 329

Query: 375 QRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREY 434
           QRL AE+++ K Q S L+ A+A +EQ+GE AL DAR KL +LE ALQKAKQDMA L+REY
Sbjct: 330 QRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREY 389

Query: 435 QELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYG----SGSSIG 490
           QE+MN KL LD+EIATYR+LLEGEE RL  EG+  VN+ V +S      G    SGS   
Sbjct: 390 QEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGIGAVNVCVSSSRGGVVCGDLCVSGSRPV 448

Query: 491 GGNL-------------GLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSSVK 537
            G++             GL    G   TT GG S G G  G      S+ G+G  GSS +
Sbjct: 449 TGSVCSAPCNGNVAVSTGLCAPCGQLNTTCGGGSCGVGSCG-----ISSLGVGSCGSSCR 503


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  424 bits (1089), Expect = e-118
 Identities = 241/463 (52%), Positives = 316/463 (68%), Gaps = 41/463 (8%)

Query: 15  RGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLYNLGGAKRVSIN 74
           R FS  SA  P  GR   +       AA   G+         FGS S+            
Sbjct: 10  RAFSCISACGPRPGRCCIT-------AAPYRGISCYRGLTGGFGSHSV------------ 50

Query: 75  GCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEVTVNQSLLTPL 134
            CG   R+G  GR+         FGY  G   G  GPS P C    I  V+VN+SLLTPL
Sbjct: 51  -CGGF-RAGSCGRS---------FGYRSG---GVCGPS-PPC----ITTVSVNESLLTPL 91

Query: 135 HLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQ 194
           +L+IDP  Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +     + 
Sbjct: 92  NLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQS 149

Query: 195 NLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFV 254
           NLEPLF+ Y   LRR+ E +  + GRL +EL ++Q+V+E +K +YE+E++ R  AENEFV
Sbjct: 150 NLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFV 209

Query: 255 ALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNL 314
           ALKKDVD AY+ K +LEA V++L +EI+F+  +++ E+  LQ+ + DTSVV+ +DN+R+L
Sbjct: 210 ALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDL 269

Query: 315 DLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMI 374
           ++D IIAE+KAQY+DI  RSRAEAESWY++K EE++ T  RHG+ LR TK+EI+E+NRMI
Sbjct: 270 NMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMI 329

Query: 375 QRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREY 434
           QRL AE+++ K Q S L+ A+A +EQ+GE AL DAR KL +LE ALQKAKQDMA L+REY
Sbjct: 330 QRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREY 389

Query: 435 QELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTS 477
           QE+MN KL LD+EIATYR+LLEGEE RL  EGV  VN+ V +S
Sbjct: 390 QEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  424 bits (1089), Expect = e-118
 Identities = 241/463 (52%), Positives = 316/463 (68%), Gaps = 41/463 (8%)

Query: 15  RGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLYNLGGAKRVSIN 74
           R FS  SA  P  GR   +       AA   G+         FGS S+            
Sbjct: 10  RAFSCISACGPRPGRCCIT-------AAPYRGISCYRGLTGGFGSHSV------------ 50

Query: 75  GCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEVTVNQSLLTPL 134
            CG   R+G  GR+         FGY  G   G  GPS P C    I  V+VN+SLLTPL
Sbjct: 51  -CGGF-RAGSCGRS---------FGYRSG---GVCGPS-PPC----ITTVSVNESLLTPL 91

Query: 135 HLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQ 194
           +L+IDP  Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +     + 
Sbjct: 92  NLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQS 149

Query: 195 NLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFV 254
           NLEPLF+ Y   LRR+ E +  + GRL +EL ++Q+V+E +K +YE+E++ R  AENEFV
Sbjct: 150 NLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFV 209

Query: 255 ALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNL 314
           ALKKDVD AY+ K +LEA V++L +EI+F+  +++ E+  LQ+ + DTSVV+ +DN+R+L
Sbjct: 210 ALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDL 269

Query: 315 DLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMI 374
           ++D IIAE+KAQY+DI  RSRAEAESWY++K EE++ T  RHG+ LR TK+EI+E+NRMI
Sbjct: 270 NMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMI 329

Query: 375 QRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREY 434
           QRL AE+++ K Q S L+ A+A +EQ+GE AL DAR KL +LE ALQKAKQDMA L+REY
Sbjct: 330 QRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREY 389

Query: 435 QELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTS 477
           QE+MN KL LD+EIATYR+LLEGEE RL  EGV  VN+ V +S
Sbjct: 390 QEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  424 bits (1089), Expect = e-118
 Identities = 241/463 (52%), Positives = 316/463 (68%), Gaps = 41/463 (8%)

Query: 15  RGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLYNLGGAKRVSIN 74
           R FS  SA  P  GR   +       AA   G+         FGS S+            
Sbjct: 10  RAFSCISACGPRPGRCCIT-------AAPYRGISCYRGLTGGFGSHSV------------ 50

Query: 75  GCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEVTVNQSLLTPL 134
            CG   R+G  GR+         FGY  G   G  GPS P C    I  V+VN+SLLTPL
Sbjct: 51  -CGGF-RAGSCGRS---------FGYRSG---GVCGPS-PPC----ITTVSVNESLLTPL 91

Query: 135 HLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQ 194
           +L+IDP  Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +     + 
Sbjct: 92  NLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQS 149

Query: 195 NLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFV 254
           NLEPLF+ Y   LRR+ E +  + GRL +EL ++Q+V+E +K +YE+E++ R  AENEFV
Sbjct: 150 NLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFV 209

Query: 255 ALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNL 314
           ALKKDVD AY+ K +LEA V++L +EI+F+  +++ E+  LQ+ + DTSVV+ +DN+R+L
Sbjct: 210 ALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDL 269

Query: 315 DLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMI 374
           ++D IIAE+KAQY+DI  RSRAEAESWY++K EE++ T  RHG+ LR TK+EI+E+NRMI
Sbjct: 270 NMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMI 329

Query: 375 QRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREY 434
           QRL AE+++ K Q S L+ A+A +EQ+GE AL DAR KL +LE ALQKAKQDMA L+REY
Sbjct: 330 QRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREY 389

Query: 435 QELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTS 477
           QE+MN KL LD+EIATYR+LLEGEE RL  EGV  VN+ V +S
Sbjct: 390 QEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  424 bits (1089), Expect = e-118
 Identities = 241/463 (52%), Positives = 316/463 (68%), Gaps = 41/463 (8%)

Query: 15  RGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLYNLGGAKRVSIN 74
           R FS  SA  P  GR   +       AA   G+         FGS S+            
Sbjct: 10  RAFSCISACGPRPGRCCIT-------AAPYRGISCYRGLTGGFGSHSV------------ 50

Query: 75  GCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEVTVNQSLLTPL 134
            CG   R+G  GR+         FGY  G   G  GPS P C    I  V+VN+SLLTPL
Sbjct: 51  -CGGF-RAGSCGRS---------FGYRSG---GVCGPS-PPC----ITTVSVNESLLTPL 91

Query: 135 HLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQ 194
           +L+IDP  Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +     + 
Sbjct: 92  NLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQS 149

Query: 195 NLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFV 254
           NLEPLF+ Y   LRR+ E +  + GRL +EL ++Q+V+E +K +YE+E++ R  AENEFV
Sbjct: 150 NLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFV 209

Query: 255 ALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNL 314
           ALKKDVD AY+ K +LEA V++L +EI+F+  +++ E+  LQ+ + DTSVV+ +DN+R+L
Sbjct: 210 ALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDL 269

Query: 315 DLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMI 374
           ++D IIAE+KAQY+DI  RSRAEAESWY++K EE++ T  RHG+ LR TK+EI+E+NRMI
Sbjct: 270 NMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMI 329

Query: 375 QRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREY 434
           QRL AE+++ K Q S L+ A+A +EQ+GE AL DAR KL +LE ALQKAKQDMA L+REY
Sbjct: 330 QRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREY 389

Query: 435 QELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTS 477
           QE+MN KL LD+EIATYR+LLEGEE RL  EGV  VN+ V +S
Sbjct: 390 QEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  420 bits (1080), Expect = e-117
 Identities = 244/462 (52%), Positives = 315/462 (68%), Gaps = 32/462 (6%)

Query: 77  GSSCRSGFGGRASNRFGVNSGFGYG------GGVGGGFSGPSFPVCPPGGIQEVTVNQSL 130
           G SC  G  G   +   V  GF  G      G   GG  GPS P C    I  V+VN+SL
Sbjct: 39  GISCYRGLTGGFGSH-SVCGGFRAGSCGRSFGYRSGGVCGPS-PPC----ITTVSVNESL 92

Query: 131 LTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSR 190
           LTPL+L+IDP  Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +   
Sbjct: 93  LTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--E 150

Query: 191 TVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAE 250
             + NLEPLF  Y   LRR+ E +  + GRL +EL ++Q+V+E +K +YE+E+  R  AE
Sbjct: 151 CCQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAE 210

Query: 251 NEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDN 310
           NEFVALKKDVD AY+ K +LEA V++L +EI+F+  +++ E+  LQ+ + DTSVV+ +DN
Sbjct: 211 NEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDN 270

Query: 311 NRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEM 370
           +R+L++D I+AE+KAQY+DIA RSRAEAESWY++K EE++ T  RHG+ LR TK+EI+E+
Sbjct: 271 SRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINEL 330

Query: 371 NRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARL 430
           NRMIQRL AE+++ K Q S L+ A+A +EQ+GE AL DAR KL +LE ALQKAKQDMA L
Sbjct: 331 NRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACL 390

Query: 431 LREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYG----SG 486
           +REYQE+MN KL LD+EIATYR+LLEGEE RL  EGV  VN+ V +S      G    SG
Sbjct: 391 IREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSSSRGGVVCGDLCVSG 449

Query: 487 ---------SSIGGGNL----GLGGGSGYSFTTSGGHSLGAG 515
                    S+   GNL    GL    G   TT GG S G G
Sbjct: 450 SRPVTGSVCSAPCNGNLVVSTGLCKPCGQLNTTCGGGSCGQG 491


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,401,354
Number of Sequences: 37866
Number of extensions: 877557
Number of successful extensions: 12484
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 281
Number of HSP's successfully gapped in prelim test: 677
Number of HSP's that attempted gapping in prelim test: 5413
Number of HSP's gapped (non-prelim): 4259
length of query: 551
length of database: 18,247,518
effective HSP length: 107
effective length of query: 444
effective length of database: 14,195,856
effective search space: 6302960064
effective search space used: 6302960064
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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