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Search of human proteins with 15375314
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15375314 LIM homeobox protein 4 [Homo sapiens]
(390 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15375314 LIM homeobox protein 4 [Homo sapiens] 808 0.0
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] 507 e-144
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] 507 e-144
gi|30410785 LIM homeobox protein 1 [Homo sapiens] 245 4e-65
gi|11641283 LIM homeobox protein 5 [Homo sapiens] 245 6e-65
gi|28893581 LIM homeobox transcription factor 1, alpha isoform a... 184 2e-46
gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens] 182 6e-46
gi|21956641 ISL LIM homeobox 2 [Homo sapiens] 160 2e-39
gi|115387114 islet-1 [Homo sapiens] 158 9e-39
gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens] 155 8e-38
gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens] 155 8e-38
gi|50083287 LIM homeobox 8 [Homo sapiens] 152 5e-37
gi|4505005 LIM domain only 1 [Homo sapiens] 126 3e-29
gi|30795196 LIM homeobox protein 2 [Homo sapiens] 126 4e-29
gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens] 124 1e-28
gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens] 124 1e-28
gi|5803072 LIM domain only 4 [Homo sapiens] 121 9e-28
gi|21361802 LIM domain only 3 [Homo sapiens] 121 1e-27
gi|47778935 LIM domain only 3 [Homo sapiens] 121 1e-27
gi|4505001 LIM domain kinase 1 [Homo sapiens] 100 4e-21
gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens] 98 1e-20
gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens] 98 1e-20
gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens] 98 1e-20
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] 88 1e-17
gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens] 88 1e-17
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 87 2e-17
gi|194272207 actin binding LIM protein family, member 2 isoform ... 85 1e-16
gi|153792514 actin binding LIM protein family, member 2 isoform ... 85 1e-16
gi|194272204 actin binding LIM protein family, member 2 isoform ... 85 1e-16
gi|194272202 actin binding LIM protein family, member 2 isoform ... 85 1e-16
>gi|15375314 LIM homeobox protein 4 [Homo sapiens]
Length = 390
Score = 808 bits (2086), Expect = 0.0
Identities = 390/390 (100%), Positives = 390/390 (100%)
Query: 1 MMQSATVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADC 60
MMQSATVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADC
Sbjct: 1 MMQSATVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADC 60
Query: 61 QMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIIC 120
QMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIIC
Sbjct: 61 QMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIIC 120
Query: 121 NRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSP 180
NRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSP
Sbjct: 121 NRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSP 180
Query: 181 KPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQ 240
KPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQ
Sbjct: 181 KPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQ 240
Query: 241 EKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQ 300
EKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQ
Sbjct: 241 EKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQ 300
Query: 301 DLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAGGPT 360
DLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAGGPT
Sbjct: 301 DLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAGGPT 360
Query: 361 SDISTGSSVGYPDFPTSPGSWLDEMDHPPF 390
SDISTGSSVGYPDFPTSPGSWLDEMDHPPF
Sbjct: 361 SDISTGSSVGYPDFPTSPGSWLDEMDHPPF 390
>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
Length = 397
Score = 507 bits (1306), Expect = e-144
Identities = 250/377 (66%), Positives = 299/377 (79%), Gaps = 16/377 (4%)
Query: 25 QQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKR 84
++IP CAGC+QHILD+FILK LDRHWHS CLKC+DC LA+RCFSR SVYCK+DFFKR
Sbjct: 26 REIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKR 85
Query: 85 FGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDY 144
FGTKC ACQ GIPPTQVVR+AQDFVYHLHCFAC++C RQLATGDEFYLMED RLVCK DY
Sbjct: 86 FGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 145
Query: 145 ETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVW 204
ETAKQ ++EA AKRPRTTITAKQLETLK+AY SPKPARHVREQLSSETGLDMRVVQVW
Sbjct: 146 ETAKQR-EAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVW 204
Query: 205 FQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQIL 264
FQNRRAKEKRLKKDAGR RWGQ+++++KRSRG SK +K+S E SD+E+SF ++ L
Sbjct: 205 FQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQD-SDAEVSFPDEPSL 263
Query: 265 SELGHTNRIYGNVGDVT------GGQLMNGSFSMDGTG----QSYQDLRDGSPYGIPQSP 314
+E+G N +YG++G+ T G L G+FS++ G + Y++LR GSPYG+P SP
Sbjct: 264 AEMGPANGLYGSLGEPTQALGRPSGAL--GNFSLEHGGLAGPEQYRELRPGSPYGVPPSP 321
Query: 315 SSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAG-GPTSDISTGSSVGYPD 373
++ SLP PLL+ L Y D++LG++ G +R +AG GP+SD+STGSS GYPD
Sbjct: 322 AAPQSLPGPQPLLSSLVYP-DTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPD 380
Query: 374 FPTSPGSWLDEMDHPPF 390
FP SP SWLDE+DH F
Sbjct: 381 FPASPASWLDEVDHAQF 397
>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
Length = 402
Score = 507 bits (1306), Expect = e-144
Identities = 250/377 (66%), Positives = 299/377 (79%), Gaps = 16/377 (4%)
Query: 25 QQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKR 84
++IP CAGC+QHILD+FILK LDRHWHS CLKC+DC LA+RCFSR SVYCK+DFFKR
Sbjct: 31 REIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKR 90
Query: 85 FGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDY 144
FGTKC ACQ GIPPTQVVR+AQDFVYHLHCFAC++C RQLATGDEFYLMED RLVCK DY
Sbjct: 91 FGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 150
Query: 145 ETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVW 204
ETAKQ ++EA AKRPRTTITAKQLETLK+AY SPKPARHVREQLSSETGLDMRVVQVW
Sbjct: 151 ETAKQR-EAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVW 209
Query: 205 FQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQIL 264
FQNRRAKEKRLKKDAGR RWGQ+++++KRSRG SK +K+S E SD+E+SF ++ L
Sbjct: 210 FQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQD-SDAEVSFPDEPSL 268
Query: 265 SELGHTNRIYGNVGDVT------GGQLMNGSFSMDGTG----QSYQDLRDGSPYGIPQSP 314
+E+G N +YG++G+ T G L G+FS++ G + Y++LR GSPYG+P SP
Sbjct: 269 AEMGPANGLYGSLGEPTQALGRPSGAL--GNFSLEHGGLAGPEQYRELRPGSPYGVPPSP 326
Query: 315 SSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAG-GPTSDISTGSSVGYPD 373
++ SLP PLL+ L Y D++LG++ G +R +AG GP+SD+STGSS GYPD
Sbjct: 327 AAPQSLPGPQPLLSSLVYP-DTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPD 385
Query: 374 FPTSPGSWLDEMDHPPF 390
FP SP SWLDE+DH F
Sbjct: 386 FPASPASWLDEVDHAQF 402
>gi|30410785 LIM homeobox protein 1 [Homo sapiens]
Length = 406
Score = 245 bits (626), Expect = 4e-65
Identities = 151/429 (35%), Positives = 216/429 (50%), Gaps = 103/429 (24%)
Query: 30 CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKRFGTKC 89
CAGC + ILD+F+L VLDR WH C++C +C+ L ++CFSR G +YCK DFF+ FGTKC
Sbjct: 4 CAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCFGTKC 63
Query: 90 TACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYET--- 146
C QGI P+ +VR+A+ V+HL+CF C++CN+QL+TG+E Y++++ + VCKEDY +
Sbjct: 64 AGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLSNSS 123
Query: 147 --------------------------------------------AKQNDDSEAGAKR--P 160
+ +NDD GAKR P
Sbjct: 124 VAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGAKRRGP 183
Query: 161 RTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK--- 217
RTTI AKQLETLK A+ +PKP RH+REQL+ ETGL+MRV+QVWFQNRR+KE+R+K+
Sbjct: 184 RTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSA 243
Query: 218 -DAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYGN 276
A RH F++S +R R + + + + SF D + + Y
Sbjct: 244 LGARRH---AFFRSPRRMRPLVDRLEPGEL----IPNGPFSFYGD-------YQSEYY-- 287
Query: 277 VGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPL---LNGLDYT 333
G G +Y G P Q+P + +PS P L GL++
Sbjct: 288 -----------------GPGGNYDFFPQGPPSSQAQTPVDLPFVPSSGPSGTPLGGLEHP 330
Query: 334 VDSN---------LGIIAHAGQGVSQTLRAMAGGPTSDIST---GSSVGYPDFPTSPG-S 380
+ + I+AH G S + GP +S G S + + G S
Sbjct: 331 LPGHHPSSEAQRFTDILAHP-PGDSPSPEPSLPGPLHSMSAEVFGPSPPFSSLSVNGGAS 389
Query: 381 WLDEMDHPP 389
+ + + HPP
Sbjct: 390 YGNHLSHPP 398
>gi|11641283 LIM homeobox protein 5 [Homo sapiens]
Length = 402
Score = 245 bits (625), Expect = 6e-65
Identities = 120/258 (46%), Positives = 165/258 (63%), Gaps = 55/258 (21%)
Query: 30 CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKRFGTKC 89
CAGC + ILD+F+L VLDR WH C++C +C+ L+++CFSR G +YCK DFF+RFGTKC
Sbjct: 5 CAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFRRFGTKC 64
Query: 90 TACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDY----- 144
C QGI P+ +VRKA+ V+HL+CF C++CN+QL+TG+E Y++++ + VCK+DY
Sbjct: 65 AGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYLSSSS 124
Query: 145 ----------------------------------------ETA-KQNDDSEAGAKR--PR 161
ETA +N++ +G KR PR
Sbjct: 125 LKEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGTKRRGPR 184
Query: 162 TTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK---- 217
TTI AKQLETLK A+ +PKP RH+REQL+ ETGL+MRV+QVWFQNRR+KE+R+K+
Sbjct: 185 TTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSAL 244
Query: 218 DAGRHRWGQFYKSVKRSR 235
A RH F++S +R R
Sbjct: 245 GARRH---AFFRSPRRMR 259
>gi|28893581 LIM homeobox transcription factor 1, alpha isoform a
[Homo sapiens]
Length = 382
Score = 184 bits (466), Expect = 2e-46
Identities = 98/233 (42%), Positives = 131/233 (56%), Gaps = 35/233 (15%)
Query: 19 MLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCK 78
+LG + C GC + ILD+F+L++ D WH C++CA C+ L CF R +YCK
Sbjct: 24 LLGRAVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCK 83
Query: 79 EDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRL 138
D+ K F KC C + I P + V +AQ VYHL CF C +C RQL GDEF L E G+L
Sbjct: 84 YDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKE-GQL 142
Query: 139 VCKEDYETAKQ--------------NDDSEA------GA--------------KRPRTTI 164
+CK DYE ++ +DD E+ GA KRPRT +
Sbjct: 143 LCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRPKRPRTIL 202
Query: 165 TAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 217
T +Q K +++ S KP R VRE L++ETGL +RVVQVWFQN+RAK K+L +
Sbjct: 203 TTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLAR 255
>gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens]
Length = 372
Score = 182 bits (461), Expect = 6e-46
Identities = 104/265 (39%), Positives = 144/265 (54%), Gaps = 45/265 (16%)
Query: 10 EGAVKGLPEMLGVPM-QQIPQ---CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLA 65
E A++ P LGV + P C GC + I D+F+++V + WH CL+CA CQ L
Sbjct: 9 EHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALT 68
Query: 66 DRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLA 125
C+ R +YCK+D+ + F KC+ C + I PT+ V +A + VYHL CF C +C RQL
Sbjct: 69 TSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLR 128
Query: 126 TGDEFYLMEDGRLVCKEDYETAK------QNDDSEA------------------------ 155
GDEF L E G+L+CK DYE K D+S++
Sbjct: 129 KGDEFVLKE-GQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSG 187
Query: 156 -------GAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNR 208
KRPRT +T +Q K +++ S KP R VRE L++ETGL +RVVQVWFQN+
Sbjct: 188 DDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQ 247
Query: 209 RAKEKRLKKDAGRHRWGQFYKSVKR 233
RAK K+L A RH+ Q ++ +R
Sbjct: 248 RAKMKKL---ARRHQQQQEQQNSQR 269
>gi|21956641 ISL LIM homeobox 2 [Homo sapiens]
Length = 359
Score = 160 bits (405), Expect = 2e-39
Identities = 88/223 (39%), Positives = 117/223 (52%), Gaps = 39/223 (17%)
Query: 30 CAGCNQHILDKFILKVL-DRHWHSSCLKCADCQMQLADRC--FSRAGSVYCKEDFFKRFG 86
C GC I D+FIL+V D WH++CLKCA+C L + C F R G YCK D+ + FG
Sbjct: 27 CVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFG 86
Query: 87 TKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDY-- 144
KC CQ G + +V +A+D VYH+ CF C +C+RQL GDEF L E L+C+ D+
Sbjct: 87 IKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREH-ELLCRADHGL 145
Query: 145 --ETAKQNDDSEAG-------------------AKRP------------RTTITAKQLET 171
E A G A RP RT + KQL T
Sbjct: 146 LLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQLHT 205
Query: 172 LKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKR 214
L+ Y +P+P ++EQL TGL RV++VWFQN+R K+K+
Sbjct: 206 LRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 248
>gi|115387114 islet-1 [Homo sapiens]
Length = 349
Score = 158 bits (399), Expect = 9e-39
Identities = 84/226 (37%), Positives = 116/226 (51%), Gaps = 39/226 (17%)
Query: 27 IPQCAGCNQHILDKFILKVL-DRHWHSSCLKCADCQMQLADRC--FSRAGSVYCKEDFFK 83
I C GC I D++IL+V D WH++CLKCA+C L + C F R G YCK D+ +
Sbjct: 14 ISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIR 73
Query: 84 RFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKED 143
+G KC C G V +A+ VYH+ CF C+ C+RQL GDEF L EDG L C+ D
Sbjct: 74 LYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDG-LFCRAD 132
Query: 144 YETAK-------------------QNDDSEAGAKRP----------------RTTITAKQ 168
++ + Q A++P RT + KQ
Sbjct: 133 HDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNEKQ 192
Query: 169 LETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKR 214
L TL+ Y +P+P ++EQL TGL RV++VWFQN+R K+K+
Sbjct: 193 LHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 238
>gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens]
Length = 377
Score = 155 bits (391), Expect = 8e-38
Identities = 78/208 (37%), Positives = 118/208 (56%), Gaps = 24/208 (11%)
Query: 30 CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADR--CFSRAGSVYCKEDFFKRFGT 87
C+ C ILD+++LKV + WH CL+C+ C+ L + C+ + ++CK D+F RFGT
Sbjct: 99 CSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGT 158
Query: 88 KCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETA 147
KC C + I + VR+A+ YHL CFAC C RQL+TG+EF L+E+ +++C+ Y+T
Sbjct: 159 KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEE-KVLCRIHYDTM 217
Query: 148 KQN---------------------DDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHV 186
+N D AKR RT+ TA+QL+ ++ + P
Sbjct: 218 IENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQT 277
Query: 187 REQLSSETGLDMRVVQVWFQNRRAKEKR 214
++L+ TGL RV+QVWFQN RA+ K+
Sbjct: 278 LQKLADMTGLSRRVIQVWFQNCRARHKK 305
>gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]
Length = 392
Score = 155 bits (391), Expect = 8e-38
Identities = 78/208 (37%), Positives = 118/208 (56%), Gaps = 24/208 (11%)
Query: 30 CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADR--CFSRAGSVYCKEDFFKRFGT 87
C+ C ILD+++LKV + WH CL+C+ C+ L + C+ + ++CK D+F RFGT
Sbjct: 99 CSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGT 158
Query: 88 KCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETA 147
KC C + I + VR+A+ YHL CFAC C RQL+TG+EF L+E+ +++C+ Y+T
Sbjct: 159 KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEE-KVLCRIHYDTM 217
Query: 148 KQN---------------------DDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHV 186
+N D AKR RT+ TA+QL+ ++ + P
Sbjct: 218 IENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQT 277
Query: 187 REQLSSETGLDMRVVQVWFQNRRAKEKR 214
++L+ TGL RV+QVWFQN RA+ K+
Sbjct: 278 LQKLADMTGLSRRVIQVWFQNCRARHKK 305
>gi|50083287 LIM homeobox 8 [Homo sapiens]
Length = 356
Score = 152 bits (384), Expect = 5e-37
Identities = 77/209 (36%), Positives = 117/209 (55%), Gaps = 25/209 (11%)
Query: 30 CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADR--CFSRAGSVYCKEDFFKRFGT 87
C C I+DK++LKV D WH CL C+ C+ L C+ + ++CK D+F+R+GT
Sbjct: 75 CNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGT 134
Query: 88 KCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYE-- 145
+C+ C + I T VR+A+ VYHL CFAC C RQL+TG+EF L+E+ +++C+ Y+
Sbjct: 135 RCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEE-KVLCRVHYDCM 193
Query: 146 --------------------TAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARH 185
+Q+ + AKR RT+ TA QL+ ++ + P
Sbjct: 194 LDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQ 253
Query: 186 VREQLSSETGLDMRVVQVWFQNRRAKEKR 214
++L+ TGL RV+QVWFQN RA+ K+
Sbjct: 254 TLQKLAERTGLSRRVIQVWFQNCRARHKK 282
>gi|4505005 LIM domain only 1 [Homo sapiens]
Length = 156
Score = 126 bits (317), Expect = 3e-29
Identities = 57/146 (39%), Positives = 92/146 (63%), Gaps = 6/146 (4%)
Query: 15 GLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLAD---RCFSR 71
G+P + P + CAGCN+ I D+++LK LD++WH CLKCA C +L + +++
Sbjct: 9 GVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTK 68
Query: 72 AGSVYCKEDFFKRFGT--KCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDE 129
A + C+ D+ + FGT C AC + IP ++V +A+D VYHL CFAC +CN++ GD+
Sbjct: 69 ANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDK 128
Query: 130 FYLMEDGRLVCKEDYETAKQNDDSEA 155
F+L ++ ++C+ DYE + N E+
Sbjct: 129 FFL-KNNMILCQMDYEEGQLNGTFES 153
>gi|30795196 LIM homeobox protein 2 [Homo sapiens]
Length = 406
Score = 126 bits (316), Expect = 4e-29
Identities = 54/125 (43%), Positives = 79/125 (63%), Gaps = 4/125 (3%)
Query: 30 CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADR--CFSRAGSVYCKEDFFKRFGT 87
CAGC I D++ L +D+ WH CLKC +C++ L CFS+ GS+YCKED+++RF
Sbjct: 53 CAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSV 112
Query: 88 -KCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYET 146
+C C GI +++V +A+D VYHL+CF C CN+ L TGD F M+D + C+ +E
Sbjct: 113 QRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFG-MKDSLVYCRLHFEA 171
Query: 147 AKQND 151
Q +
Sbjct: 172 LLQGE 176
Score = 51.2 bits (121), Expect = 2e-06
Identities = 27/62 (43%), Positives = 37/62 (59%)
Query: 153 SEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKE 212
S KR RT+ QL T+K+ + + P +QL+ +TGL RV+QVWFQN RAK
Sbjct: 262 SSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKF 321
Query: 213 KR 214
+R
Sbjct: 322 RR 323
>gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens]
Length = 397
Score = 124 bits (312), Expect = 1e-28
Identities = 54/125 (43%), Positives = 79/125 (63%), Gaps = 4/125 (3%)
Query: 30 CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADR--CFSRAGSVYCKEDFFKRFGT 87
CAGC I D++ L +D+ WH CLKC +C++ L CF++ GS+YCKED+++RF
Sbjct: 71 CAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSV 130
Query: 88 -KCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYET 146
+C C GI +++V +A+D VYHL CF C CN+ L TGD F M+D + C+ +ET
Sbjct: 131 QRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFG-MKDSLVYCRAHFET 189
Query: 147 AKQND 151
Q +
Sbjct: 190 LLQGE 194
Score = 57.8 bits (138), Expect = 2e-08
Identities = 54/205 (26%), Positives = 82/205 (40%), Gaps = 27/205 (13%)
Query: 27 IPQCAGCNQHI-LDKFILKVLDRHWHSSCLKCADCQMQLA--DRCFSRAGSVYCKEDFFK 83
+ +CA C+ I + +++ D +H SC C+ C L D + VYC+ F
Sbjct: 130 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFE- 188
Query: 84 RFGTKCTACQQGIPP----TQVVRKAQDFVYHLHCFACIICN------RQLATGDEFYLM 133
T Q PP T++ K+ + + A G +
Sbjct: 189 ------TLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNY 242
Query: 134 EDGRLVCKEDYETAKQNDDS----EAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQ 189
G C E+ D KR RT+ QL T+K+ + + P +Q
Sbjct: 243 NSG---CNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQ 299
Query: 190 LSSETGLDMRVVQVWFQNRRAKEKR 214
L+ +TGL RV+QVWFQN RAK +R
Sbjct: 300 LAQKTGLTKRVLQVWFQNARAKFRR 324
>gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens]
Length = 388
Score = 124 bits (312), Expect = 1e-28
Identities = 54/125 (43%), Positives = 79/125 (63%), Gaps = 4/125 (3%)
Query: 30 CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADR--CFSRAGSVYCKEDFFKRFGT 87
CAGC I D++ L +D+ WH CLKC +C++ L CF++ GS+YCKED+++RF
Sbjct: 62 CAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSV 121
Query: 88 -KCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYET 146
+C C GI +++V +A+D VYHL CF C CN+ L TGD F M+D + C+ +ET
Sbjct: 122 QRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFG-MKDSLVYCRAHFET 180
Query: 147 AKQND 151
Q +
Sbjct: 181 LLQGE 185
Score = 57.8 bits (138), Expect = 2e-08
Identities = 54/205 (26%), Positives = 82/205 (40%), Gaps = 27/205 (13%)
Query: 27 IPQCAGCNQHI-LDKFILKVLDRHWHSSCLKCADCQMQLA--DRCFSRAGSVYCKEDFFK 83
+ +CA C+ I + +++ D +H SC C+ C L D + VYC+ F
Sbjct: 121 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFE- 179
Query: 84 RFGTKCTACQQGIPP----TQVVRKAQDFVYHLHCFACIICN------RQLATGDEFYLM 133
T Q PP T++ K+ + + A G +
Sbjct: 180 ------TLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNY 233
Query: 134 EDGRLVCKEDYETAKQNDDS----EAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQ 189
G C E+ D KR RT+ QL T+K+ + + P +Q
Sbjct: 234 NSG---CNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQ 290
Query: 190 LSSETGLDMRVVQVWFQNRRAKEKR 214
L+ +TGL RV+QVWFQN RAK +R
Sbjct: 291 LAQKTGLTKRVLQVWFQNARAKFRR 315
>gi|5803072 LIM domain only 4 [Homo sapiens]
Length = 165
Score = 121 bits (304), Expect = 9e-28
Identities = 55/127 (43%), Positives = 79/127 (62%), Gaps = 6/127 (4%)
Query: 29 QCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLAD---RCFSRAGSVYCKEDFFKRF 85
+CAGC I D+F+L +D +WHS CLKC+ CQ QL D C++++G + C+ D+ + F
Sbjct: 22 RCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDIGTSCYTKSGMILCRNDYIRLF 81
Query: 86 GTK--CTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKED 143
G C+AC Q IP +++V +AQ VYHL CF C C +L GD F+ + +G L C+ D
Sbjct: 82 GNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRNRLVPGDRFHYI-NGSLFCEHD 140
Query: 144 YETAKQN 150
TA N
Sbjct: 141 RPTALIN 147
>gi|21361802 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 121 bits (303), Expect = 1e-27
Identities = 55/133 (41%), Positives = 86/133 (64%), Gaps = 7/133 (5%)
Query: 19 MLGVPMQQIPQ-CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLAD---RCFSRAGS 74
ML V P+ CAGCN+ I D+++LK LD++WH CLKCA C +L + +++A
Sbjct: 1 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL 60
Query: 75 VYCKEDFFKRFGT--KCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYL 132
+ C+ D+ + FG C AC + IP ++V +A+D VYHL CFAC +CN++ GD+F+L
Sbjct: 61 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL 120
Query: 133 MEDGRLVCKEDYE 145
++ ++C+ DYE
Sbjct: 121 -KNNMILCQTDYE 132
>gi|47778935 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 121 bits (303), Expect = 1e-27
Identities = 55/133 (41%), Positives = 86/133 (64%), Gaps = 7/133 (5%)
Query: 19 MLGVPMQQIPQ-CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLAD---RCFSRAGS 74
ML V P+ CAGCN+ I D+++LK LD++WH CLKCA C +L + +++A
Sbjct: 1 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL 60
Query: 75 VYCKEDFFKRFGT--KCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYL 132
+ C+ D+ + FG C AC + IP ++V +A+D VYHL CFAC +CN++ GD+F+L
Sbjct: 61 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL 120
Query: 133 MEDGRLVCKEDYE 145
++ ++C+ DYE
Sbjct: 121 -KNNMILCQTDYE 132
>gi|4505001 LIM domain kinase 1 [Homo sapiens]
Length = 647
Score = 99.8 bits (247), Expect = 4e-21
Identities = 42/127 (33%), Positives = 67/127 (52%), Gaps = 1/127 (0%)
Query: 18 EMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYC 77
E +G ++P CA C Q I D L+ L+ WH+ C +C DC L+ + + + G ++C
Sbjct: 13 ERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYYEKDGQLFC 72
Query: 78 KEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGR 137
K+D++ R+G C C + I +V A + YH CF C+ C + GD + L+E +
Sbjct: 73 KKDYWARYGESCHGCSEQI-TKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSK 131
Query: 138 LVCKEDY 144
L C Y
Sbjct: 132 LYCGHCY 138
>gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 97.8 bits (242), Expect = 1e-20
Identities = 48/139 (34%), Positives = 76/139 (54%), Gaps = 8/139 (5%)
Query: 18 EMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLAD---RCFSRAGS 74
E+L +P + C GC Q+I D++ LK +D++WH CL C C +L + R + + G
Sbjct: 19 EVLQIPPSLLT-CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGR 77
Query: 75 VYCKEDFFKRFGTK--CTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYL 132
C+ D+ + FG C +C + I ++ + +D VYHL CF C C + GD YL
Sbjct: 78 KLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDR-YL 136
Query: 133 MEDGRLVCKED-YETAKQN 150
+ + +VC++D YE K N
Sbjct: 137 LINSDIVCEQDIYEWTKIN 155
>gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 97.8 bits (242), Expect = 1e-20
Identities = 48/139 (34%), Positives = 76/139 (54%), Gaps = 8/139 (5%)
Query: 18 EMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLAD---RCFSRAGS 74
E+L +P + C GC Q+I D++ LK +D++WH CL C C +L + R + + G
Sbjct: 19 EVLQIPPSLLT-CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGR 77
Query: 75 VYCKEDFFKRFGTK--CTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYL 132
C+ D+ + FG C +C + I ++ + +D VYHL CF C C + GD YL
Sbjct: 78 KLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDR-YL 136
Query: 133 MEDGRLVCKED-YETAKQN 150
+ + +VC++D YE K N
Sbjct: 137 LINSDIVCEQDIYEWTKIN 155
>gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens]
Length = 227
Score = 97.8 bits (242), Expect = 1e-20
Identities = 48/139 (34%), Positives = 76/139 (54%), Gaps = 8/139 (5%)
Query: 18 EMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLAD---RCFSRAGS 74
E+L +P + C GC Q+I D++ LK +D++WH CL C C +L + R + + G
Sbjct: 88 EVLQIPPSLLT-CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGR 146
Query: 75 VYCKEDFFKRFGTK--CTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYL 132
C+ D+ + FG C +C + I ++ + +D VYHL CF C C + GD YL
Sbjct: 147 KLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDR-YL 205
Query: 133 MEDGRLVCKED-YETAKQN 150
+ + +VC++D YE K N
Sbjct: 206 LINSDIVCEQDIYEWTKIN 224
>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
Length = 718
Score = 88.2 bits (217), Expect = 1e-17
Identities = 57/172 (33%), Positives = 79/172 (45%), Gaps = 19/172 (11%)
Query: 16 LPEMLGVPMQQIPQ-------CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRC 68
L ++ PM P+ CAGC + I + L LD+ WH C KC C L
Sbjct: 145 LCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEY 204
Query: 69 FSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGD 128
S+ G+ YC++D+ FG KC AC Q I T V +A D YH C C CN+ G+
Sbjct: 205 ISKDGAPYCEKDYQGLFGVKCEACHQFI--TGKVLEAGDKHYHPSCARCSRCNQMFTEGE 262
Query: 129 EFYLMEDGRLV----CKEDYETAKQ----NDDSEAGAKRPRTTITAKQLETL 172
E YL G V CK+ +T ++ SE+ RP ++I T+
Sbjct: 263 EMYL--QGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTI 312
Score = 58.5 bits (140), Expect = 1e-08
Identities = 29/88 (32%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 42 ILKVLDRHWHSSCLKCADCQMQLADR-CFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQ 100
+L+V +H+H C C C LA F + G C D+ + +GT+C C + +
Sbjct: 50 VLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEV 109
Query: 101 VVRKAQDFVYHLHCFACIICNRQLATGD 128
V + YH +CFAC IC R GD
Sbjct: 110 VTALGK--TYHPNCFACTICKRPFPPGD 135
Score = 35.0 bits (79), Expect = 0.12
Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 4/57 (7%)
Query: 89 CTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYE 145
C C G P V + Q +H+ CF C +C LA G + +++G +C DY+
Sbjct: 39 CHKC--GEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGG--FFIKNGEYLCTLDYQ 91
>gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]
Length = 778
Score = 88.2 bits (217), Expect = 1e-17
Identities = 57/172 (33%), Positives = 79/172 (45%), Gaps = 19/172 (11%)
Query: 16 LPEMLGVPMQQIPQ-------CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRC 68
L ++ PM P+ CAGC + I + L LD+ WH C KC C L
Sbjct: 205 LCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEY 264
Query: 69 FSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGD 128
S+ G+ YC++D+ FG KC AC Q I T V +A D YH C C CN+ G+
Sbjct: 265 ISKDGAPYCEKDYQGLFGVKCEACHQFI--TGKVLEAGDKHYHPSCARCSRCNQMFTEGE 322
Query: 129 EFYLMEDGRLV----CKEDYETAKQ----NDDSEAGAKRPRTTITAKQLETL 172
E YL G V CK+ +T ++ SE+ RP ++I T+
Sbjct: 323 EMYL--QGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTI 372
Score = 58.5 bits (140), Expect = 1e-08
Identities = 29/88 (32%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 42 ILKVLDRHWHSSCLKCADCQMQLADR-CFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQ 100
+L+V +H+H C C C LA F + G C D+ + +GT+C C + +
Sbjct: 110 VLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEV 169
Query: 101 VVRKAQDFVYHLHCFACIICNRQLATGD 128
V + YH +CFAC IC R GD
Sbjct: 170 VTALGK--TYHPNCFACTICKRPFPPGD 195
Score = 35.0 bits (79), Expect = 0.12
Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 4/57 (7%)
Query: 89 CTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYE 145
C C G P V + Q +H+ CF C +C LA G + +++G +C DY+
Sbjct: 99 CHKC--GEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGG--FFIKNGEYLCTLDYQ 151
>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
Length = 746
Score = 87.4 bits (215), Expect = 2e-17
Identities = 60/192 (31%), Positives = 83/192 (43%), Gaps = 19/192 (9%)
Query: 16 LPEMLGVPMQQIPQ-------CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRC 68
L ++ PM P+ CAGC + I + L LD+ WH C KC C L
Sbjct: 145 LCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEY 204
Query: 69 FSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGD 128
S+ G+ YC++D+ FG KC AC Q I T V +A D YH C C CN+ G+
Sbjct: 205 ISKDGAPYCEKDYQGLFGVKCEACHQFI--TGKVLEAGDKHYHPSCARCSRCNQMFTEGE 262
Query: 129 EFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKN-----SPKPA 183
E YL G V D KQ+ +E + P ++ K+ + S +P
Sbjct: 263 EMYL--QGSTVWHPD---CKQSTKTEEKLRLPNIRRSSSDFFYSKSLIRRTGRSPSLQPT 317
Query: 184 RHVREQLSSETG 195
R E + S G
Sbjct: 318 RTSSESIYSRPG 329
Score = 58.5 bits (140), Expect = 1e-08
Identities = 29/88 (32%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 42 ILKVLDRHWHSSCLKCADCQMQLADR-CFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQ 100
+L+V +H+H C C C LA F + G C D+ + +GT+C C + +
Sbjct: 50 VLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEV 109
Query: 101 VVRKAQDFVYHLHCFACIICNRQLATGD 128
V + YH +CFAC IC R GD
Sbjct: 110 VTALGK--TYHPNCFACTICKRPFPPGD 135
Score = 35.0 bits (79), Expect = 0.12
Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 4/57 (7%)
Query: 89 CTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYE 145
C C G P V + Q +H+ CF C +C LA G + +++G +C DY+
Sbjct: 39 CHKC--GEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGG--FFIKNGEYLCTLDYQ 91
>gi|194272207 actin binding LIM protein family, member 2 isoform 7
[Homo sapiens]
Length = 470
Score = 85.1 bits (209), Expect = 1e-16
Identities = 54/175 (30%), Positives = 79/175 (45%), Gaps = 11/175 (6%)
Query: 25 QQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKR 84
Q + C GC I + L LD+HWH C KC C L S+ G YC+ D+ +
Sbjct: 148 QGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAK 207
Query: 85 FGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDY 144
FG +C +C++ I T V +A + YH C C+ C + A G+E YL G +
Sbjct: 208 FGIRCDSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYL--QGSSIWHPAC 263
Query: 145 ETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMR 199
A + +D R + T T+ + A S P+R + +L E LD R
Sbjct: 264 RQAARTED------RNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYR 311
Score = 60.1 bits (144), Expect = 3e-09
Identities = 36/116 (31%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 17 PEMLGVPMQQIPQCAG-CNQ--HILDKFILKVLDRHWHSSCLKCADCQMQLADR-CFSRA 72
P+ P+++ P A CN ++ +L+V D+++H C C C LA+ F R
Sbjct: 7 PQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQ 66
Query: 73 GSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGD 128
G C D+ + +GT+C +C Q I V A YH CF C +C GD
Sbjct: 67 GEYICTLDYQRLYGTRCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.4 bits (80), Expect = 0.089
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 2/44 (4%)
Query: 102 VRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYE 145
V + QD +H+ CF C C LA G + + G +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
>gi|153792514 actin binding LIM protein family, member 2 isoform 6
[Homo sapiens]
Length = 521
Score = 85.1 bits (209), Expect = 1e-16
Identities = 54/175 (30%), Positives = 79/175 (45%), Gaps = 11/175 (6%)
Query: 25 QQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKR 84
Q + C GC I + L LD+HWH C KC C L S+ G YC+ D+ +
Sbjct: 148 QGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAK 207
Query: 85 FGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDY 144
FG +C +C++ I T V +A + YH C C+ C + A G+E YL G +
Sbjct: 208 FGIRCDSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYL--QGSSIWHPAC 263
Query: 145 ETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMR 199
A + +D R + T T+ + A S P+R + +L E LD R
Sbjct: 264 RQAARTED------RNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYR 311
Score = 60.1 bits (144), Expect = 3e-09
Identities = 36/116 (31%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 17 PEMLGVPMQQIPQCAG-CNQ--HILDKFILKVLDRHWHSSCLKCADCQMQLADR-CFSRA 72
P+ P+++ P A CN ++ +L+V D+++H C C C LA+ F R
Sbjct: 7 PQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQ 66
Query: 73 GSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGD 128
G C D+ + +GT+C +C Q I V A YH CF C +C GD
Sbjct: 67 GEYICTLDYQRLYGTRCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.4 bits (80), Expect = 0.089
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 2/44 (4%)
Query: 102 VRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYE 145
V + QD +H+ CF C C LA G + + G +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
>gi|194272204 actin binding LIM protein family, member 2 isoform 5
[Homo sapiens]
Length = 531
Score = 85.1 bits (209), Expect = 1e-16
Identities = 54/175 (30%), Positives = 79/175 (45%), Gaps = 11/175 (6%)
Query: 25 QQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKR 84
Q + C GC I + L LD+HWH C KC C L S+ G YC+ D+ +
Sbjct: 148 QGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAK 207
Query: 85 FGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDY 144
FG +C +C++ I T V +A + YH C C+ C + A G+E YL G +
Sbjct: 208 FGIRCDSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYL--QGSSIWHPAC 263
Query: 145 ETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMR 199
A + +D R + T T+ + A S P+R + +L E LD R
Sbjct: 264 RQAARTED------RNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYR 311
Score = 60.1 bits (144), Expect = 3e-09
Identities = 36/116 (31%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 17 PEMLGVPMQQIPQCAG-CNQ--HILDKFILKVLDRHWHSSCLKCADCQMQLADR-CFSRA 72
P+ P+++ P A CN ++ +L+V D+++H C C C LA+ F R
Sbjct: 7 PQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQ 66
Query: 73 GSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGD 128
G C D+ + +GT+C +C Q I V A YH CF C +C GD
Sbjct: 67 GEYICTLDYQRLYGTRCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.4 bits (80), Expect = 0.089
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 2/44 (4%)
Query: 102 VRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYE 145
V + QD +H+ CF C C LA G + + G +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
>gi|194272202 actin binding LIM protein family, member 2 isoform 4
[Homo sapiens]
Length = 559
Score = 85.1 bits (209), Expect = 1e-16
Identities = 54/175 (30%), Positives = 79/175 (45%), Gaps = 11/175 (6%)
Query: 25 QQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKR 84
Q + C GC I + L LD+HWH C KC C L S+ G YC+ D+ +
Sbjct: 148 QGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAK 207
Query: 85 FGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDY 144
FG +C +C++ I T V +A + YH C C+ C + A G+E YL G +
Sbjct: 208 FGIRCDSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYL--QGSSIWHPAC 263
Query: 145 ETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMR 199
A + +D R + T T+ + A S P+R + +L E LD R
Sbjct: 264 RQAARTED------RNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYR 311
Score = 60.1 bits (144), Expect = 3e-09
Identities = 36/116 (31%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 17 PEMLGVPMQQIPQCAG-CNQ--HILDKFILKVLDRHWHSSCLKCADCQMQLADR-CFSRA 72
P+ P+++ P A CN ++ +L+V D+++H C C C LA+ F R
Sbjct: 7 PQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQ 66
Query: 73 GSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGD 128
G C D+ + +GT+C +C Q I V A YH CF C +C GD
Sbjct: 67 GEYICTLDYQRLYGTRCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.4 bits (80), Expect = 0.089
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 2/44 (4%)
Query: 102 VRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYE 145
V + QD +H+ CF C C LA G + + G +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,599,175
Number of Sequences: 37866
Number of extensions: 807864
Number of successful extensions: 3606
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 378
Number of HSP's successfully gapped in prelim test: 68
Number of HSP's that attempted gapping in prelim test: 2643
Number of HSP's gapped (non-prelim): 743
length of query: 390
length of database: 18,247,518
effective HSP length: 104
effective length of query: 286
effective length of database: 14,309,454
effective search space: 4092503844
effective search space used: 4092503844
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.