Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 150418009
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|150418009 transforming, acidic coiled-coil containing
protein 2 isoform a [Homo sapiens]
(2948 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|150418009 transforming, acidic coiled-coil containing protein... 5934 0.0
gi|45827755 transforming, acidic coiled-coil containing protein ... 2026 0.0
gi|11119414 transforming, acidic coiled-coil containing protein ... 1990 0.0
gi|45827753 transforming, acidic coiled-coil containing protein ... 1920 0.0
gi|170763517 transforming, acidic coiled-coil containing protein... 306 1e-82
gi|226246618 transforming, acidic coiled-coil containing protein... 300 1e-80
gi|170763519 transforming, acidic coiled-coil containing protein... 298 7e-80
gi|5454102 transforming, acidic coiled-coil containing protein 3... 211 9e-54
gi|163965366 nascent polypeptide-associated complex alpha subuni... 103 3e-21
gi|91982772 mucin 17 [Homo sapiens] 92 6e-18
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 91 2e-17
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 91 2e-17
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 90 3e-17
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 90 3e-17
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 90 4e-17
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 89 6e-17
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 89 6e-17
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 89 6e-17
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 89 6e-17
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 89 8e-17
gi|226437579 NAC alpha domain containing [Homo sapiens] 87 3e-16
gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens] 87 3e-16
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 85 9e-16
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 84 2e-15
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 84 3e-15
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 79 5e-14
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 79 5e-14
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 79 5e-14
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 78 1e-13
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 78 1e-13
>gi|150418009 transforming, acidic coiled-coil containing protein 2
isoform a [Homo sapiens]
Length = 2948
Score = 5934 bits (15395), Expect = 0.0
Identities = 2948/2948 (100%), Positives = 2948/2948 (100%)
Query: 1 MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCT 60
MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCT
Sbjct: 1 MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCT 60
Query: 61 ASESSASLDPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEG 120
ASESSASLDPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEG
Sbjct: 61 ASESSASLDPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEG 120
Query: 121 CLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPK 180
CLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPK
Sbjct: 121 CLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPK 180
Query: 181 EEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESR 240
EEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESR
Sbjct: 181 EEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESR 240
Query: 241 QGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYL 300
QGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYL
Sbjct: 241 QGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYL 300
Query: 301 TDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAG 360
TDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAG
Sbjct: 301 TDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAG 360
Query: 361 GSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPAS 420
GSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPAS
Sbjct: 361 GSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPAS 420
Query: 421 SLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGE 480
SLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGE
Sbjct: 421 SLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGE 480
Query: 481 HPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPS 540
HPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPS
Sbjct: 481 HPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPS 540
Query: 541 ESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQ 600
ESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQ
Sbjct: 541 ESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQ 600
Query: 601 AFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLP 660
AFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLP
Sbjct: 601 AFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLP 660
Query: 661 HKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEK 720
HKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEK
Sbjct: 661 HKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEK 720
Query: 721 SDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFHAGVPH 780
SDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFHAGVPH
Sbjct: 721 SDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFHAGVPH 780
Query: 781 PPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPETS 840
PPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPETS
Sbjct: 781 PPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPETS 840
Query: 841 IFDVLKEQAQPPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSE 900
IFDVLKEQAQPPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSE
Sbjct: 841 IFDVLKEQAQPPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSE 900
Query: 901 LQSQLPKGTLSDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRPEGACGDGQSSR 960
LQSQLPKGTLSDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRPEGACGDGQSSR
Sbjct: 901 LQSQLPKGTLSDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRPEGACGDGQSSR 960
Query: 961 VSPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQHEEACQRHPGASEA 1020
VSPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQHEEACQRHPGASEA
Sbjct: 961 VSPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQHEEACQRHPGASEA 1020
Query: 1021 ADGCSPLWGLSKREMASGNTGEAPPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETE 1080
ADGCSPLWGLSKREMASGNTGEAPPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETE
Sbjct: 1021 ADGCSPLWGLSKREMASGNTGEAPPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETE 1080
Query: 1081 ACDETQEGRQQPVPAPQQKMECWATSDAESPKLLASFPSAGEQGGEAGAAETGGSAGAGD 1140
ACDETQEGRQQPVPAPQQKMECWATSDAESPKLLASFPSAGEQGGEAGAAETGGSAGAGD
Sbjct: 1081 ACDETQEGRQQPVPAPQQKMECWATSDAESPKLLASFPSAGEQGGEAGAAETGGSAGAGD 1140
Query: 1141 PGKQQAPEKPGEATLSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDALLPAREL 1200
PGKQQAPEKPGEATLSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDALLPAREL
Sbjct: 1141 PGKQQAPEKPGEATLSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDALLPAREL 1200
Query: 1201 GGIPRSTMDFSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSAD 1260
GGIPRSTMDFSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSAD
Sbjct: 1201 GGIPRSTMDFSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSAD 1260
Query: 1261 PRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTE 1320
PRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTE
Sbjct: 1261 PRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTE 1320
Query: 1321 GPVDSMPCLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEP 1380
GPVDSMPCLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEP
Sbjct: 1321 GPVDSMPCLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEP 1380
Query: 1381 SQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGEKAGAGRSAVGK 1440
SQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGEKAGAGRSAVGK
Sbjct: 1381 SQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGEKAGAGRSAVGK 1440
Query: 1441 DLTRPLGPEKLLDGPPGVDVTLLPAPPARLQVEKKQQLAGEAEISHLALQDPASDKLLGP 1500
DLTRPLGPEKLLDGPPGVDVTLLPAPPARLQVEKKQQLAGEAEISHLALQDPASDKLLGP
Sbjct: 1441 DLTRPLGPEKLLDGPPGVDVTLLPAPPARLQVEKKQQLAGEAEISHLALQDPASDKLLGP 1500
Query: 1501 AGLTWERNLPGAGVGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQLERSRQELASGL 1560
AGLTWERNLPGAGVGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQLERSRQELASGL
Sbjct: 1501 AGLTWERNLPGAGVGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQLERSRQELASGL 1560
Query: 1561 PSPAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSGKQHQETSACDSPHGEDGPGDFAH 1620
PSPAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSGKQHQETSACDSPHGEDGPGDFAH
Sbjct: 1561 PSPAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSGKQHQETSACDSPHGEDGPGDFAH 1620
Query: 1621 TGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQST 1680
TGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQST
Sbjct: 1621 TGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQST 1680
Query: 1681 PAPPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDL 1740
PAPPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDL
Sbjct: 1681 PAPPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDL 1740
Query: 1741 VLPGSCQDPACSDKAPGMEGTAALHGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEP 1800
VLPGSCQDPACSDKAPGMEGTAALHGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEP
Sbjct: 1741 VLPGSCQDPACSDKAPGMEGTAALHGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEP 1800
Query: 1801 DETHDPKLQHLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSP 1860
DETHDPKLQHLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSP
Sbjct: 1801 DETHDPKLQHLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSP 1860
Query: 1861 VADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVS 1920
VADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVS
Sbjct: 1861 VADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVS 1920
Query: 1921 PSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPE 1980
PSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPE
Sbjct: 1921 PSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPE 1980
Query: 1981 VSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDF 2040
VSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDF
Sbjct: 1981 VSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDF 2040
Query: 2041 DNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSS 2100
DNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSS
Sbjct: 2041 DNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSS 2100
Query: 2101 GNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEE 2160
GNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEE
Sbjct: 2101 GNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEE 2160
Query: 2161 SLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGG 2220
SLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGG
Sbjct: 2161 SLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGG 2220
Query: 2221 GRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQ 2280
GRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQ
Sbjct: 2221 GRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQ 2280
Query: 2281 ENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDID 2340
ENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDID
Sbjct: 2281 ENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDID 2340
Query: 2341 KWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEI 2400
KWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEI
Sbjct: 2341 KWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEI 2400
Query: 2401 PASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPP 2460
PASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPP
Sbjct: 2401 PASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPP 2460
Query: 2461 VISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYR 2520
VISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYR
Sbjct: 2461 VISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYR 2520
Query: 2521 NSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEE 2580
NSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEE
Sbjct: 2521 NSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEE 2580
Query: 2581 TEALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFA 2640
TEALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFA
Sbjct: 2581 TEALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFA 2640
Query: 2641 SADALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIAL 2700
SADALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIAL
Sbjct: 2641 SADALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIAL 2700
Query: 2701 ASRSHQDAKREAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIIT 2760
ASRSHQDAKREAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIIT
Sbjct: 2701 ASRSHQDAKREAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIIT 2760
Query: 2761 KEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQ 2820
KEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQ
Sbjct: 2761 KEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQ 2820
Query: 2821 ALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVH 2880
ALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVH
Sbjct: 2821 ALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVH 2880
Query: 2881 AEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDE 2940
AEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDE
Sbjct: 2881 AEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDE 2940
Query: 2941 LIAKMGKS 2948
LIAKMGKS
Sbjct: 2941 LIAKMGKS 2948
>gi|45827755 transforming, acidic coiled-coil containing protein 2
isoform b [Homo sapiens]
Length = 1094
Score = 2026 bits (5248), Expect = 0.0
Identities = 1044/1131 (92%), Positives = 1050/1131 (92%), Gaps = 54/1131 (4%)
Query: 1818 TDRESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADLESP 1877
T R + PG S ++D P D SSPVADDIIQPAAPADLESP
Sbjct: 18 TPRSAQPPGNSQNIKRKQQDTPGSPDH---------RDASSSPVADDIIQPAAPADLESP 68
Query: 1878 TLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEASTPSCP 1937
TLAASSYHG D++ Q + A
Sbjct: 69 TLAASSYHG--------DVVGQVSTDLIAQ------------------------------ 90
Query: 1938 DPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV 1997
RSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV
Sbjct: 91 -------RSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV 143
Query: 1998 PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS 2057
PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS
Sbjct: 144 PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS 203
Query: 2058 DAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGS 2117
DAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGS
Sbjct: 204 DAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGS 263
Query: 2118 SSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTES 2177
SSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTES
Sbjct: 264 SSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTES 323
Query: 2178 AKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLT 2237
AKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLT
Sbjct: 324 AKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLT 383
Query: 2238 TAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKM 2297
TAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKM
Sbjct: 384 TAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKM 443
Query: 2298 PLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQ 2357
PLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQ
Sbjct: 444 PLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQ 503
Query: 2358 ESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNK 2417
ESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNK
Sbjct: 504 ESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNK 563
Query: 2418 PAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVT 2477
PAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVT
Sbjct: 564 PAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVT 623
Query: 2478 NQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQ 2537
NQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQ
Sbjct: 624 NQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQ 683
Query: 2538 DDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPR 2597
DDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPR
Sbjct: 684 DDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPR 743
Query: 2598 GLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCG 2657
GLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCG
Sbjct: 744 GLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCG 803
Query: 2658 ALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTD 2717
ALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTD
Sbjct: 804 ALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTD 863
Query: 2718 VSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRR 2777
VSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRR
Sbjct: 864 VSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRR 923
Query: 2778 EVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFR 2837
EVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFR
Sbjct: 924 EVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFR 983
Query: 2838 RYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG 2897
RYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG
Sbjct: 984 RYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG 1043
Query: 2898 KAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 2948
KAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS
Sbjct: 1044 KAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 1094
Score = 117 bits (293), Expect = 2e-25
Identities = 179/679 (26%), Positives = 244/679 (35%), Gaps = 116/679 (17%)
Query: 1 MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSI---------- 50
MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASS
Sbjct: 1 MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPA 60
Query: 51 -----------------GSVGLGGFCTASESSASLDPCLVSPEVTEPRKDPQGARGPEGS 93
VG ++ S+ + +PE T P K P
Sbjct: 61 APADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAP------ 114
Query: 94 LLPSPPPSQEREHPSSSMPFAECPPE--GCLASPAAAPEDGPQTQSPRREPAPNAPGDIA 151
P PPP E S+ P PPE GC + P DGP++ S P +
Sbjct: 115 --PPPPPEVIPEPEVSTQP----PPEEPGCGSETVPVP-DGPRSDSVEGSPFRPPSHSFS 167
Query: 152 AAFPAERD--SSTPYQ---EIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLR 206
A F ++ SS Y + + + +P+ K+ + +S P+
Sbjct: 168 AVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS 227
Query: 207 EPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVL 266
++ D G S EA V + P+A + S+
Sbjct: 228 TLSRSLSLQASDFDGASSSGNPEA---------------VALAPDAYSTGSSSASSTLKR 272
Query: 267 EKSPLKPMAPIPQ---DPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEA 323
K P P Q P +E Q E + L E L + A E
Sbjct: 273 TKKPRPPSLKKKQTTKKPTETPPVKET-QQEPDEESLVPSGENLAS---ETKTESAKTEG 328
Query: 324 EVNAASQESCQQPVGAYLPHAELPWGLPS-PALVPEAGGSGKEALDTIDVQGHPQTGMRG 382
A +E+ +P A P A P S +VP A G G+ VQ P G R
Sbjct: 329 PSPALLEETPLEP--AVGPKAACPLDSESAEGVVPPASGGGR-------VQNSPPVG-RK 378
Query: 383 TKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSR 442
T P L +PE +TP++ S A + ++ E SS
Sbjct: 379 TLP---------------LTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSE-DKSSW 422
Query: 443 ESVSKAGMPVSADAAKEVVDAGL--VGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEH 500
++ + P K V L +++ L + P P E P P +G +
Sbjct: 423 DNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAE-PNDIPIAKGTY 481
Query: 501 LNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDST 560
+ ++ P P + ++Q PK P +S P D V T
Sbjct: 482 -----TFDIDKWDDPNFNPFSSTSKMQES------PKLPQQSYNFDPDTCD-ESVDPFKT 529
Query: 561 SPAVAKEGSRSPG--DSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKP 618
S S+SP + P EA GD N + + V K P
Sbjct: 530 SSKTPSSPSKSPASFEIPASAMEANGV--DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSP 587
Query: 619 SSDAESRD-HPSSHSAQPP 636
SD S+D P++ PP
Sbjct: 588 LSDPPSQDPTPAATPETPP 606
>gi|11119414 transforming, acidic coiled-coil containing protein 2
isoform d [Homo sapiens]
Length = 1026
Score = 1990 bits (5155), Expect = 0.0
Identities = 1008/1018 (99%), Positives = 1009/1018 (99%), Gaps = 6/1018 (0%)
Query: 1937 PDPAKDLS------RSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEP 1990
P PA DL+ SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEP
Sbjct: 9 PAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEP 68
Query: 1991 GCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQ 2050
GCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQ
Sbjct: 69 GCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQ 128
Query: 2051 TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAP 2110
TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAP
Sbjct: 129 TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAP 188
Query: 2111 DAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLA 2170
DAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLA
Sbjct: 189 DAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLA 248
Query: 2171 SETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVG 2230
SETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVG
Sbjct: 249 SETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVG 308
Query: 2231 RKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIG 2290
RKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIG
Sbjct: 309 RKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIG 368
Query: 2291 KKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPF 2350
KKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPF
Sbjct: 369 KKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPF 428
Query: 2351 SSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGV 2410
SSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGV
Sbjct: 429 SSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGV 488
Query: 2411 DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATD 2470
DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATD
Sbjct: 489 DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATD 548
Query: 2471 EEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEK 2530
EEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEK
Sbjct: 549 EEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEK 608
Query: 2531 IGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAK 2590
IGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAK
Sbjct: 609 IGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAK 668
Query: 2591 NQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLA 2650
NQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLA
Sbjct: 669 NQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLA 728
Query: 2651 HPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKR 2710
HPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKR
Sbjct: 729 HPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKR 788
Query: 2711 EAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKD 2770
EAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKD
Sbjct: 789 EAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKD 848
Query: 2771 KYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEK 2830
KYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEK
Sbjct: 849 KYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEK 908
Query: 2831 SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANA 2890
SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANA
Sbjct: 909 SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANA 968
Query: 2891 EIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 2948
EIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS
Sbjct: 969 EIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 1026
Score = 36.6 bits (83), Expect = 0.38
Identities = 61/264 (23%), Positives = 87/264 (32%), Gaps = 45/264 (17%)
Query: 2278 NQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAK----- 2332
+Q P P + + M + +TPE A P P P IP +
Sbjct: 4 SQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQP 63
Query: 2333 -------GTYTF---DIDKWDDPNFNPFSSTSKM------QESPKLPQQSYNFDPDTCDE 2376
G+ T D + D +PF S ++ P +YN D D E
Sbjct: 64 PPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNI-E 122
Query: 2377 SVDPFKT------------------SSKTPSSP-SKSPASFEIPASAMEANGVDGDGLNK 2417
VD F+T T S P SKS S + A + +G G +
Sbjct: 123 LVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPE 182
Query: 2418 PAKKKKTPLKTDTFRVKKSPKRSPLSDPPS--QDPTPAATPETPPVISAVVHATDEEKLA 2475
T + + KR+ PPS + T ETPPV DEE L
Sbjct: 183 AVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPV-KETQQEPDEESLV 241
Query: 2476 VTNQKWTCMTVDLEADKQDYPQPS 2499
+ + T E+ K + P P+
Sbjct: 242 PSGENLASET-KTESAKTEGPSPA 264
Score = 35.8 bits (81), Expect = 0.64
Identities = 131/593 (22%), Positives = 195/593 (32%), Gaps = 90/593 (15%)
Query: 61 ASES-SASLDPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPE 119
ASE+ S+ + +PE T P K P P PPP E S+ P PPE
Sbjct: 19 ASEAMSSDSEEAFETPESTTPVKAPPAP--------PPPPPEVIPEPEVSTQP----PPE 66
Query: 120 --GCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERD--SSTPYQ---EIAAVPS 172
GC + P DGP++ S P +A F ++ SS Y + +
Sbjct: 67 EPGCGSETVPVP-DGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVD 125
Query: 173 AGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAG 232
+ +P+ K+ + +S P+ ++ D G S EA
Sbjct: 126 TFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEA-- 183
Query: 233 GFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQ---DPAPRASDRE 289
V + P+A + S+ K P P Q P +E
Sbjct: 184 -------------VALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKE 230
Query: 290 RGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWG 349
Q E + L E L + A E A +E+ +P A P A P
Sbjct: 231 T-QQEPDEESLVPSGENLAS---ETKTESAKTEGPSPALLEETPLEP--AVGPKAACPLD 284
Query: 350 LPS-PALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPS 408
S +VP A G G+ VQ P G R T P L +PE
Sbjct: 285 SESAEGVVPPASGGGR-------VQNSPPVG-RKTLP---------------LTTAPEAG 321
Query: 409 LLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGL--V 466
+TP++ S A + ++ E SS ++ + P K V L
Sbjct: 322 EVTPSDSGGQEDSPAKGLSVRLEFDYSE-DKSSWDNQQENPPPTKKIGKKPVAKMPLRRP 380
Query: 467 GLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEV 526
+++ L + P P E P P +G + + ++ P P + ++
Sbjct: 381 KMKKTPEKLDNTPASPPRSPAE-PNDIPIAKGTY-----TFDIDKWDDPNFNPFSSTSKM 434
Query: 527 QPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPG--DSPGGKEEAPE 584
Q PK P +S P D V TS S+SP + P EA
Sbjct: 435 QES------PKLPQQSYNFDPDTCD-ESVDPFKTSSKTPSSPSKSPASFEIPASAMEANG 487
Query: 585 PPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRD-HPSSHSAQPP 636
GD N + + V K P SD S+D P++ PP
Sbjct: 488 V--DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPP 538
>gi|45827753 transforming, acidic coiled-coil containing protein 2
isoform c [Homo sapiens]
Length = 996
Score = 1920 bits (4974), Expect = 0.0
Identities = 978/1018 (96%), Positives = 979/1018 (96%), Gaps = 36/1018 (3%)
Query: 1937 PDPAKDLS------RSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEP 1990
P PA DL+ SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEP
Sbjct: 9 PAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEP 68
Query: 1991 GCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQ 2050
GCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQ
Sbjct: 69 GCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQ 128
Query: 2051 TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAP 2110
TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAP
Sbjct: 129 TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAP 188
Query: 2111 DAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLA 2170
DAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLA
Sbjct: 189 DAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLA 248
Query: 2171 SETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVG 2230
SETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVG
Sbjct: 249 SETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVG 308
Query: 2231 RKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIG 2290
RKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIG
Sbjct: 309 RKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIG 368
Query: 2291 KKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPF 2350
KKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPF
Sbjct: 369 KKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPF 428
Query: 2351 SSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGV 2410
SSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGV
Sbjct: 429 SSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGV 488
Query: 2411 DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATD 2470
DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATD
Sbjct: 489 DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATD 548
Query: 2471 EEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEK 2530
EEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEK
Sbjct: 549 EEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEK 608
Query: 2531 IGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAK 2590
IGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAK
Sbjct: 609 IGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAK 668
Query: 2591 NQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLA 2650
NQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLA
Sbjct: 669 NQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLA 728
Query: 2651 HPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKR 2710
HPVSLCGALDYLEPDLAEKNPPLFAQKLQ R
Sbjct: 729 HPVSLCGALDYLEPDLAEKNPPLFAQKLQ------------------------------R 758
Query: 2711 EAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKD 2770
EAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKD
Sbjct: 759 EAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKD 818
Query: 2771 KYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEK 2830
KYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEK
Sbjct: 819 KYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEK 878
Query: 2831 SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANA 2890
SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANA
Sbjct: 879 SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANA 938
Query: 2891 EIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 2948
EIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS
Sbjct: 939 EIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 996
Score = 36.6 bits (83), Expect = 0.38
Identities = 61/264 (23%), Positives = 87/264 (32%), Gaps = 45/264 (17%)
Query: 2278 NQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAK----- 2332
+Q P P + + M + +TPE A P P P IP +
Sbjct: 4 SQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQP 63
Query: 2333 -------GTYTF---DIDKWDDPNFNPFSSTSKM------QESPKLPQQSYNFDPDTCDE 2376
G+ T D + D +PF S ++ P +YN D D E
Sbjct: 64 PPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNI-E 122
Query: 2377 SVDPFKT------------------SSKTPSSP-SKSPASFEIPASAMEANGVDGDGLNK 2417
VD F+T T S P SKS S + A + +G G +
Sbjct: 123 LVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPE 182
Query: 2418 PAKKKKTPLKTDTFRVKKSPKRSPLSDPPS--QDPTPAATPETPPVISAVVHATDEEKLA 2475
T + + KR+ PPS + T ETPPV DEE L
Sbjct: 183 AVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPV-KETQQEPDEESLV 241
Query: 2476 VTNQKWTCMTVDLEADKQDYPQPS 2499
+ + T E+ K + P P+
Sbjct: 242 PSGENLASET-KTESAKTEGPSPA 264
Score = 35.8 bits (81), Expect = 0.64
Identities = 131/593 (22%), Positives = 195/593 (32%), Gaps = 90/593 (15%)
Query: 61 ASES-SASLDPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPE 119
ASE+ S+ + +PE T P K P P PPP E S+ P PPE
Sbjct: 19 ASEAMSSDSEEAFETPESTTPVKAPPAP--------PPPPPEVIPEPEVSTQP----PPE 66
Query: 120 --GCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERD--SSTPYQ---EIAAVPS 172
GC + P DGP++ S P +A F ++ SS Y + +
Sbjct: 67 EPGCGSETVPVP-DGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVD 125
Query: 173 AGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAG 232
+ +P+ K+ + +S P+ ++ D G S EA
Sbjct: 126 TFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEA-- 183
Query: 233 GFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQ---DPAPRASDRE 289
V + P+A + S+ K P P Q P +E
Sbjct: 184 -------------VALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKE 230
Query: 290 RGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWG 349
Q E + L E L + A E A +E+ +P A P A P
Sbjct: 231 T-QQEPDEESLVPSGENLAS---ETKTESAKTEGPSPALLEETPLEP--AVGPKAACPLD 284
Query: 350 LPS-PALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPS 408
S +VP A G G+ VQ P G R T P L +PE
Sbjct: 285 SESAEGVVPPASGGGR-------VQNSPPVG-RKTLP---------------LTTAPEAG 321
Query: 409 LLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGL--V 466
+TP++ S A + ++ E SS ++ + P K V L
Sbjct: 322 EVTPSDSGGQEDSPAKGLSVRLEFDYSE-DKSSWDNQQENPPPTKKIGKKPVAKMPLRRP 380
Query: 467 GLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEV 526
+++ L + P P E P P +G + + ++ P P + ++
Sbjct: 381 KMKKTPEKLDNTPASPPRSPAE-PNDIPIAKGTY-----TFDIDKWDDPNFNPFSSTSKM 434
Query: 527 QPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPG--DSPGGKEEAPE 584
Q PK P +S P D V TS S+SP + P EA
Sbjct: 435 QES------PKLPQQSYNFDPDTCD-ESVDPFKTSSKTPSSPSKSPASFEIPASAMEANG 487
Query: 585 PPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRD-HPSSHSAQPP 636
GD N + + V K P SD S+D P++ PP
Sbjct: 488 V--DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPP 538
>gi|170763517 transforming, acidic coiled-coil containing protein 1
isoform 1 [Homo sapiens]
Length = 805
Score = 306 bits (785), Expect = 1e-82
Identities = 279/891 (31%), Positives = 410/891 (46%), Gaps = 146/891 (16%)
Query: 2091 ASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPT---ET 2147
A + + G+PE + S SS S T + P + + P+
Sbjct: 27 AGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGNFETPEAETPIRSPFKESCDPSLGLAG 86
Query: 2148 PPVKETQ-QEPDEESLVPSGENLASETKTESAKTEGPSPAL-------LEETPLEPAVGP 2199
P K + QE DE+ + E +S+T ++ ++ E P A+ E P
Sbjct: 87 PGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAIDSHSVKNFREEPEHDFSKI 146
Query: 2200 KAACPLDSESAEGVVPPASGGGRVQNS--PPVGRKTLPLTTAPEAGEVTPSDSGGQEDSP 2257
P E+ + A G + + V K LP + P D+ E
Sbjct: 147 SIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSS---------PPDALQDEAMT 197
Query: 2258 AKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPAS 2317
+ V LE D + ++ E P + +KP +PLR+ K + +T A+
Sbjct: 198 EGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKP-KPVPLRK---KAIGGEFSDTNAA 253
Query: 2318 PPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQSYNFDPDTCDE 2376
+P + K +Y F ++ D+ N +P ++ Q+SP L + DT D
Sbjct: 254 VEGTP-------LPKASYHFSPEELDE-NTSPLLGDARFQKSPPDLKETPGTLSSDTNDS 305
Query: 2377 SVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKS 2436
V+ ++ SSP K F +EA L + TP K + KS
Sbjct: 306 GVE---LGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTP-KIQKDGISKS 361
Query: 2437 P----------KRSPLSDPPSQ-DPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT 2485
+ PLS S+ DP+ +P P S H+ + ++++
Sbjct: 362 AGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGS---HSVLQNSPPLSSEGSYHFD 418
Query: 2486 VDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQ 2545
D + D +P+ T + + F SPT G+ + + ++PKK
Sbjct: 419 PDNFDESMDPFKPT---TTLTSSDFCSPT-----------------GNHVNEILESPKKA 458
Query: 2546 ALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAP--NQ 2603
L+ + C E ++ ++++ V ++ N+
Sbjct: 459 KSRLI-------------------TSGCKVKKHETQSLALDACSRDEGAVISQISDISNR 499
Query: 2604 ESHLQVPEKSS-----QKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGA 2658
+ H EK + QK A G P E +E F ++ +S + H A
Sbjct: 500 DGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEY------FECSNVPVSTINH------A 547
Query: 2659 LDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDV 2718
E + ++ QK++E+ + +E+ +A V
Sbjct: 548 FSSSEAGIEKET----CQKMEEDGSTVLGLLES--------------------SAEKAPV 583
Query: 2719 SISKTALYSRIGTAEVEKPA-GLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRR 2777
S+S E P G+ + D + L + R EIITKE E +EWK KYEE+R+
Sbjct: 584 SVSCGG----------ESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQ 633
Query: 2778 EVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFR 2837
EV+EMRKIVAEYEKTIAQMIEDEQR S ++ QQL +EKEQALADLNSVE+SL+DLFR
Sbjct: 634 EVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFR 693
Query: 2838 RYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG 2897
RYE +K VLEGF+KNEE LK+CAQ+YL+RVK+EEQRYQALK+HAEEKLD+AN EIAQVR
Sbjct: 694 RYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRT 753
Query: 2898 KAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 2948
KA+ E AA A LRKEQ++V++LER L+QKN+EIEELTKICDELIAK+GK+
Sbjct: 754 KAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKT 804
Score = 127 bits (318), Expect = 2e-28
Identities = 172/657 (26%), Positives = 268/657 (40%), Gaps = 123/657 (18%)
Query: 1924 PAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVST 1983
P GD E + + K LS SSDSE FETPE+ TP+++P P + P +
Sbjct: 35 PEGDPEEEDSQA---ETKSLSFSSDSEGNFETPEAETPIRSPFKESCDPSLGLAGPGAKS 91
Query: 1984 QPPPEE---------PGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSG 2034
Q E C S+T P E SHS +E +
Sbjct: 92 QESQEADEQLVAEVVEKCSSKTCSKP-----SENEVPQQAIDSHSVKNFREEPEH----- 141
Query: 2035 TYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSL--SLQAS 2092
DF I +V F D+ + + T+ +S L S +LQ
Sbjct: 142 ----DFSKISIVRPFSI---ETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPPDALQDE 194
Query: 2093 DFDGASSSGNPEAVALAP-DAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVK 2151
S EA A A A ++ S + +KP+P L+KK
Sbjct: 195 AMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKA------------ 242
Query: 2152 ETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAE 2211
+ E +A EG TPL PKA+ E +
Sbjct: 243 -----------------IGGEFSDTNAAVEG--------TPL-----PKASYHFSPEELD 272
Query: 2212 GVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSE 2271
P G R Q SPP ++T P T + + +DSG + ++ ++LEFD++E
Sbjct: 273 ENTSPLLGDARFQKSPPDLKET-PGTLSSDT-----NDSGVELGEESRSSPLKLEFDFTE 326
Query: 2272 DKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEP--NDIP 2329
D + + ++ P +K+G+K + + PK++K + ++ P +P D P
Sbjct: 327 DTGNIEARKALP---RKLGRKLGSTL---TPKIQKD----GISKSAGLEQPTDPVARDGP 376
Query: 2330 IAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQ-SYNFDPDTCDESVDPFKTSSKTP 2388
+++ + D +W+ P+FNPF S S +Q SP L + SY+FDPD DES+DPFK ++
Sbjct: 377 LSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDPFKPTTTLT 436
Query: 2389 SSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQ 2448
SS SP + + L P KK K+ L T +VKK +S D S+
Sbjct: 437 SSDFCSPTGNHV-----------NEILESP-KKAKSRLITSGCKVKKHETQSLALDACSR 484
Query: 2449 DPTPAATPETPPVISAVVHATDEEKLAVTN--QKWTCMTVDLEADKQ-DYPQPSDLSTFV 2505
D A + + + HATDEEKLA T+ QK V E ++ +Y + S++
Sbjct: 485 D-EGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVST 543
Query: 2506 NETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSS 2562
FSS ++ + ME+ GS++ L L+ +++++PV S
Sbjct: 544 INHAFSSSEAGIEKET---CQKMEEDGSTV-----------LGLLESSAEKAPVSVS 586
Score = 37.0 bits (84), Expect = 0.29
Identities = 48/190 (25%), Positives = 78/190 (41%), Gaps = 22/190 (11%)
Query: 1872 ADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEA 1931
A +E L +SYH S + + ++ SP A S + +P + D ++
Sbjct: 252 AAVEGTPLPKASYH------FSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDS 305
Query: 1932 STPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPE---PEVSTQPPPE 1988
+ SRSS + F+ E T ++A A P + P++ +
Sbjct: 306 GVELGEE-----SRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK 360
Query: 1989 EPGCGSETVPVP-DGPRSD-SVEGSPFRPPSHSFS-----AVFDEDKPIASSGTYNLDFD 2041
G T PV DGP S S + P + S SF+ +V P++S G+Y+ D D
Sbjct: 361 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD 420
Query: 2042 NI-ELVDTFQ 2050
N E +D F+
Sbjct: 421 NFDESMDPFK 430
>gi|226246618 transforming, acidic coiled-coil containing protein 1
isoform 3 [Homo sapiens]
Length = 610
Score = 300 bits (769), Expect = 1e-80
Identities = 237/676 (35%), Positives = 336/676 (49%), Gaps = 115/676 (17%)
Query: 2293 PVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSS 2352
P + LR+PK +K S + E +P K +Y F ++ D+ N +P
Sbjct: 29 PSRRSKLRKPKPVPLRKKAIGGEFSDTNAAVEGTPLP--KASYHFSPEELDE-NTSPLLG 85
Query: 2353 TSKMQESPK-LPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVD 2411
++ Q+SP L + DT D V+ ++ SSP K F +EA
Sbjct: 86 DARFQKSPPDLKETPGTLSSDTNDSGVE---LGEESRSSPLKLEFDFTEDTGNIEARKAL 142
Query: 2412 GDGLNKPAKKKKTPLKTDTFRVKKSP----------KRSPLSDPPSQ-DPTPAATPETPP 2460
L + TP K + KS + PLS S+ DP+ +P P
Sbjct: 143 PRKLGRKLGSTLTP-KIQKDGISKSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNP 201
Query: 2461 VISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYR 2520
S H+ + ++++ D + D +P+ T + + F SPT
Sbjct: 202 FGS---HSVLQNSPPLSSEGSYHFDPDNFDESMDPFKPT---TTLTSSDFCSPT------ 249
Query: 2521 NSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEE 2580
G+ + + ++PKK L+ + C E
Sbjct: 250 -----------GNHVNEILESPKKAKSRLI-------------------TSGCKVKKHET 279
Query: 2581 TEALVNTAAKNQHPVPRGLAP--NQESHLQVPEKSS-----QKELEAMGLGTPSEAIEIT 2633
++ ++++ V ++ N++ H EK + QK A G P E +E
Sbjct: 280 QSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEY- 338
Query: 2634 APEGSFASADALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALK 2693
F ++ +S + H A E + ++ QK++E+ + +E+
Sbjct: 339 -----FECSNVPVSTINH------AFSSSEAGIEKET----CQKMEEDGSTVLGLLES-- 381
Query: 2694 LARQIALASRSHQDAKREAAHPTDVSISKTALYSRIGTAEVEKPA-GLLFQQPDLDSALQ 2752
+A VS+S E P G+ + D + L
Sbjct: 382 ------------------SAEKAPVSVSCGG----------ESPLDGICLSESDKTAVLT 413
Query: 2753 IARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQ 2812
+ R EIITKE E +EWK KYEE+R+EV+EMRKIVAEYEKTIAQMIEDEQR S ++ Q
Sbjct: 414 LIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQ 473
Query: 2813 QLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQ 2872
QL +EKEQALADLNSVE+SL+DLFRRYE +K VLEGF+KNEE LK+CAQ+YL+RVK+EEQ
Sbjct: 474 QLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQ 533
Query: 2873 RYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIE 2932
RYQALK+HAEEKLD+AN EIAQVR KA+ E AA A LRKEQ++V++LER L+QKN+EIE
Sbjct: 534 RYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIE 593
Query: 2933 ELTKICDELIAKMGKS 2948
ELTKICDELIAK+GK+
Sbjct: 594 ELTKICDELIAKLGKT 609
Score = 112 bits (279), Expect = 7e-24
Identities = 112/383 (29%), Positives = 183/383 (47%), Gaps = 54/383 (14%)
Query: 2186 ALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEV 2245
A +E TPL PKA+ E + P G R Q SPP ++T P T + +
Sbjct: 57 AAVEGTPL-----PKASYHFSPEELDENTSPLLGDARFQKSPPDLKET-PGTLSSDT--- 107
Query: 2246 TPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMK 2305
+DSG + ++ ++LEFD++ED + + ++ P +K+G+K + + PK++
Sbjct: 108 --NDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALP---RKLGRKLGSTLT---PKIQ 159
Query: 2306 KTPEKLDNTPASPPRSPAEP--NDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLP 2363
K + ++ P +P D P+++ + D +W+ P+FNPF S S +Q SP L
Sbjct: 160 KD----GISKSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLS 215
Query: 2364 QQ-SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKK 2422
+ SY+FDPD DES+DPFK ++ SS SP + + L P KK
Sbjct: 216 SEGSYHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHV-----------NEILESP-KKA 263
Query: 2423 KTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTN--QK 2480
K+ L T +VKK +S D S+D A + + + HATDEEKLA T+ QK
Sbjct: 264 KSRLITSGCKVKKHETQSLALDACSRD-EGAVISQISDISNRDGHATDEEKLASTSCGQK 322
Query: 2481 WTCMTVDLEADKQ-DYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDD 2539
V E ++ +Y + S++ FSS ++ + ME+ GS++
Sbjct: 323 SAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKET---CQKMEEDGSTV---- 375
Query: 2540 DAPKKQALYLMFDTSQESPVKSS 2562
L L+ +++++PV S
Sbjct: 376 -------LGLLESSAEKAPVSVS 391
Score = 37.0 bits (84), Expect = 0.29
Identities = 48/190 (25%), Positives = 78/190 (41%), Gaps = 22/190 (11%)
Query: 1872 ADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEA 1931
A +E L +SYH S + + ++ SP A S + +P + D ++
Sbjct: 57 AAVEGTPLPKASYH------FSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDS 110
Query: 1932 STPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPE---PEVSTQPPPE 1988
+ SRSS + F+ E T ++A A P + P++ +
Sbjct: 111 GVELGEE-----SRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK 165
Query: 1989 EPGCGSETVPVP-DGPRSD-SVEGSPFRPPSHSFS-----AVFDEDKPIASSGTYNLDFD 2041
G T PV DGP S S + P + S SF+ +V P++S G+Y+ D D
Sbjct: 166 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD 225
Query: 2042 NI-ELVDTFQ 2050
N E +D F+
Sbjct: 226 NFDESMDPFK 235
>gi|170763519 transforming, acidic coiled-coil containing protein 1
isoform 2 [Homo sapiens]
Length = 395
Score = 298 bits (762), Expect = 7e-80
Identities = 149/210 (70%), Positives = 179/210 (85%)
Query: 2739 GLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIE 2798
G+ + D + L + R EIITKE E +EWK KYEE+R+EV+EMRKIVAEYEKTIAQMIE
Sbjct: 185 GICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIE 244
Query: 2799 DEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKR 2858
DEQR S ++ QQL +EKEQALADLNSVE+SL+DLFRRYE +K VLEGF+KNEE LK+
Sbjct: 245 DEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKK 304
Query: 2859 CAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVD 2918
CAQ+YL+RVK+EEQRYQALK+HAEEKLD+AN EIAQVR KA+ E AA A LRKEQ++V+
Sbjct: 305 CAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVE 364
Query: 2919 ALERTLEQKNKEIEELTKICDELIAKMGKS 2948
+LER L+QKN+EIEELTKICDELIAK+GK+
Sbjct: 365 SLERALQQKNQEIEELTKICDELIAKLGKT 394
>gi|5454102 transforming, acidic coiled-coil containing protein 3
[Homo sapiens]
Length = 838
Score = 211 bits (537), Expect = 9e-54
Identities = 107/208 (51%), Positives = 151/208 (72%), Gaps = 7/208 (3%)
Query: 2740 LLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIED 2799
L + Q DLD+ ++ + E E + + EE + +E+ KI+ +E+ + Q +E+
Sbjct: 637 LQYSQKDLDAVVKAT-------QEENRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEE 689
Query: 2800 EQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRC 2859
Q++K +S +Q+++ EK+Q DLNS+EKS +DLF+R+EK KEV+EG+RKNEE LK+C
Sbjct: 690 VQKQKELSKAEIQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYRKNEESLKKC 749
Query: 2860 AQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDA 2919
++YL+R+ +E QRYQALK HAEEKL AN EIAQVR KAQ E A QASLRKEQ+R+ +
Sbjct: 750 VEDYLARITQEGQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQS 809
Query: 2920 LERTLEQKNKEIEELTKICDELIAKMGK 2947
LE+T+EQK KE EELT+ICD+LI+KM K
Sbjct: 810 LEKTVEQKTKENEELTRICDDLISKMEK 837
Score = 102 bits (254), Expect = 6e-21
Identities = 192/868 (22%), Positives = 329/868 (37%), Gaps = 177/868 (20%)
Query: 2054 PRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAY 2113
P + +NQ+ K+T + L AS G+ SS ALA
Sbjct: 95 PVWTQKENQQLIKEVDAKTTHGILQKPVEADTDLLGDASPAFGSGSSSESGPGALADLDC 154
Query: 2114 STGSSSASSTLKRTKKPRPPSLKKKQTTKKPTET-------PPVKETQQEP-----DEES 2161
S+ S S S+ + P S +Q ++ + P ET ++P ++
Sbjct: 155 SSSSQSPGSSENQMVSPGKVSGSPEQAVEENLSSYSLDRRVTPASETLEDPCRTESQHKA 214
Query: 2162 LVPSGENLASETKTESAKTEGP------SPALLEETPLEPAVGPKAAC---PLDSESAEG 2212
P G + +T E +PA + +P P PK AC PL E
Sbjct: 215 ETPHGAEEECKAETPHGAEEECRHGGVCAPAAVATSP--PGAIPKEACGGAPLQGLPGEA 272
Query: 2213 VVPPASGGGRVQNSPPVGRKTL-------PLTTAP-------EAGEVTPSD--SGGQEDS 2256
+ PA G V P G +TL P +TAP A ++P + + GQ S
Sbjct: 273 LGCPAGVGTPV---PADGTQTLTCAHTSAPESTAPTNHLVAGRAMTLSPQEEVAAGQMAS 329
Query: 2257 PAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRP--KMKKTPEKLDNT 2314
++ V+LEFD S+ +S + PP +++G++ K PLR+ + +K P++++
Sbjct: 330 SSRSGPVKLEFDVSDGATS-----KRAPPPRRLGERSGLKPPLRKAAVRQQKAPQEVEED 384
Query: 2315 PASPPRSPA-EPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDT 2373
RS A E +P ++G+Y D DK DDPNF PF +K
Sbjct: 385 DG---RSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGGDTK----------------SG 425
Query: 2374 CDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRV 2433
C E+ P ++P + PA+ ++ A PA ++ P
Sbjct: 426 CSEAQPP-----ESPETRLGQPAAEQLHAG--------------PATEEPGPCL------ 460
Query: 2434 KKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLE-ADK 2492
SQ A+ +TP V A T E K N T + ++
Sbjct: 461 -------------SQQLHSASAEDTPVVQLAAETPTAESKERALNSASTSLPTSCPGSEP 507
Query: 2493 QDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFD 2552
Q + + E F P E L E++Y+E+ G+S + A +KQ+LYL FD
Sbjct: 508 VPTHQQGQPALELKEESFRDPAEVLG--TGAEVDYLEQFGTS-SFKESALRKQSLYLKFD 564
Query: 2553 -TSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPE 2611
++SP + PV S + N+ P R P
Sbjct: 565 PLLRDSPGRPVPVATETS----------------SMHGANETPSGR------------PR 596
Query: 2612 KSSQKELEAMG---LGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLEPDLAE 2668
++ E + +G + P + AP G P+S +D L+ ++
Sbjct: 597 EAKLVEFDFLGALDIPVPGPPPGVPAPGGP-------------PLSTGPIVDLLQ--YSQ 641
Query: 2669 KNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTALYSR 2728
K+ + QEE R E L + + L D E + + K
Sbjct: 642 KDLDAVVKATQEENRELRSRCEELH-GKNLELG--KIMDRFEEVVYQAMEEVQK---QKE 695
Query: 2729 IGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAE 2788
+ AE++K +L ++ L + L + + K+ E R+ ++K V +
Sbjct: 696 LSKAEIQK---VLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYRKNEESLKKCVED 752
Query: 2789 YEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQ-------ALADLNSVEKSLADLFRRYEK 2841
Y +A++ ++ QR +++ ++L L E+ A A+ +++ SL R +
Sbjct: 753 Y---LARITQEGQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQS 809
Query: 2842 MKEVLEGFRKNEEVLKRCAQEYLSRVKK 2869
+++ +E K E L R + +S+++K
Sbjct: 810 LEKTVEQKTKENEELTRICDDLISKMEK 837
Score = 42.0 bits (97), Expect = 0.009
Identities = 107/438 (24%), Positives = 153/438 (34%), Gaps = 102/438 (23%)
Query: 1473 EKKQQLAGE--AEISHLALQDP--ASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLRE- 1527
++ QQL E A+ +H LQ P A LLG A P G G P L +
Sbjct: 100 KENQQLIKEVDAKTTHGILQKPVEADTDLLGDAS-------PAFGSGSSSESGPGALADL 152
Query: 1528 --DERPEGPGAAWPGL--EGQAYSQLERSRQELASGLP-----SPAA-TQELPVERAAAF 1577
+ PG++ + G+ E++ +E S +PA+ T E P R +
Sbjct: 153 DCSSSSQSPGSSENQMVSPGKVSGSPEQAVEENLSSYSLDRRVTPASETLEDPC-RTESQ 211
Query: 1578 QVAPHSHGEEAVAQDRIPSGKQHQETSACDSPHGEDGPGDFAHTGVPGHVPRSTCAPSPQ 1637
A HG E + P G + + HG T PG +P+ C +P
Sbjct: 212 HKAETPHGAEEECKAETPHGAEEE------CRHGGVCAPAAVATSPPGAIPKEACGGAP- 264
Query: 1638 REVLTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGEVADTPLEPGK 1697
L L GE G AG+ A G Q+ T T
Sbjct: 265 ---------------LQGLPGEAL-GCPAGVGTPVPADGTQTLTCAHTSAPESTAPTNHL 308
Query: 1698 VAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPG 1757
VAG A +TLS E A+G + A ++R+ G + L D A S +AP
Sbjct: 309 VAGRA------MTLSPQEE--VAAGQM--ASSSRS-----GPVKLEFDVSDGATSKRAPP 353
Query: 1758 MEGTAALHGDSPA----------RPQQAKEQPG-----PERPIPAGDGKVCVS------- 1795
G P PQ+ +E G + P+PA G +
Sbjct: 354 PRRLGERSGLKPPLRKAAVRQQKAPQEVEEDDGRSGAGEDPPMPASRGSYHLDWDKMDDP 413
Query: 1796 -------------SPPEPDETHDPKLQHLAPEELHTDRESPRPGPSM---LPSVPKKDAP 1839
S +P E+ + +L A E+LH + PGP + L S +D P
Sbjct: 414 NFIPFGGDTKSGCSEAQPPESPETRLGQPAAEQLHAGPATEEPGPCLSQQLHSASAEDTP 473
Query: 1840 RVMDKVTSDETRGAEGTE 1857
V + ET AE E
Sbjct: 474 VVQ---LAAETPTAESKE 488
Score = 40.0 bits (92), Expect = 0.034
Identities = 118/542 (21%), Positives = 179/542 (33%), Gaps = 101/542 (18%)
Query: 21 SAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSASLDPCLVSPEVTEP 80
S+Q PG+S+N GSP+ ++ S L T + + DPC TE
Sbjct: 157 SSQSPGSSENQMVSPGKVSGSPEQAVEENLSSYSLDRRVTPASETLE-DPCR-----TES 210
Query: 81 RKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRR 140
+ + G E P E E C G + +PAA
Sbjct: 211 QHKAETPHGAEEECKAETPHGAEEE----------CR-HGGVCAPAAV------------ 247
Query: 141 EPAPNAPGDIAAAFPAERDSSTPYQ----EIAAVPSAGRERQPKEEGQKSSFSFSSGIDQ 196
A + PG A P E P Q E P+ P + Q + + +S +
Sbjct: 248 --ATSPPG----AIPKEACGGAPLQGLPGEALGCPAGVGTPVPADGTQTLTCAHTSAPES 301
Query: 197 SPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAA 256
+ + + M S ++E A G + SR G ++ A +
Sbjct: 302 TAPTNHLVAGRAMTL-------------SPQEEVAAGQMASSSRSGPVKLEFDVSDGATS 348
Query: 257 QQGTESSAVLEKSPLKP---MAPIPQDPAPR---ASDRERGQGEAPPQYLT--------D 302
++ + E+S LKP A + Q AP+ D G GE PP + D
Sbjct: 349 KRAPPPRRLGERSGLKPPLRKAAVRQQKAPQEVEEDDGRSGAGEDPPMPASRGSYHLDWD 408
Query: 303 DLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGS 362
++ EA+ + + QP L HA P P L + +
Sbjct: 409 KMDDPNFIPFGGDTKSGCSEAQPPESPETRLGQPAAEQL-HAGPATEEPGPCLSQQLHSA 467
Query: 363 GKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPT-EEAHPASS 421
E DT VQ +T +K A LP S S PT ++ PA
Sbjct: 468 SAE--DTPVVQLAAETPTAESKER------ALNSASTSLPTSCPGSEPVPTHQQGQPALE 519
Query: 422 L--ASF--PAAQIPIA-----VEEPGSSS--RESVSKAGMPVSADAAKEVVDAGLVGLER 470
L SF PA + +E+ G+SS ++ K + + D V +
Sbjct: 520 LKEESFRDPAEVLGTGAEVDYLEQFGTSSFKESALRKQSLYLKFDPLLRDSPGRPVPVAT 579
Query: 471 QVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGA 530
+ S + E P G P E G + ++ PPP +P PG
Sbjct: 580 ETSSMHGANETPSGRPREAKLVEFDFLG-------ALDIPVPGPPPGVP-------APGG 625
Query: 531 PP 532
PP
Sbjct: 626 PP 627
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 103 bits (256), Expect = 3e-21
Identities = 343/1642 (20%), Positives = 506/1642 (30%), Gaps = 315/1642 (19%)
Query: 1264 PGESPCPVGEPPLALENAASLKLFAG-------SLAPLLQPGAAGG--EIPAVQ-ASSGS 1313
P ES P G P + ++ A SLAP P G +P V AS
Sbjct: 649 PLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENC 708
Query: 1314 PKARTTEGPVDSMPCLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGS 1373
P A + + + L P + K + A T PG D T
Sbjct: 709 PVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKV--------DGISHTSAL 760
Query: 1374 MERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGEKAGA 1433
P + P + + SS+ TLT D + P +K A
Sbjct: 761 APVASSPKECPTEDSGASATASSK--GTLTYLADSPSPLGVSVSPQTK---RPPTKKGSA 815
Query: 1434 GRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPARLQVEKKQQLAGEAEI--SHLALQD 1491
G +L+ P+ P V+ + LP Q K + S
Sbjct: 816 GPDTPIGNLSSPVSP---------VEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT 866
Query: 1492 PASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQLER 1551
P++ L P G+T LP P +E P A P L + S +
Sbjct: 867 PSAVTPLSPKGVT----LPPKETPTPSVVNLPFPKEGPATPAPKQA-PALSMTSSSPKKA 921
Query: 1552 SRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSGKQHQETSACDSPHG 1611
G+P+ + + P AA P G A PS K A P
Sbjct: 922 RATPAPKGIPASPSPKGAPTPPAAT---PPSPKGGPAT-----PSPKWAPTPPAATPPSP 973
Query: 1612 EDGPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAGILEM 1671
+ GP + G P P + PSP+ P T G P VT
Sbjct: 974 KGGPATPSPKGAP--TPPAATPPSPK----------GGPATPSPKGAPTPPAVT------ 1015
Query: 1672 RNALGNQSTPAPPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTR 1731
P P G A TP G A T A+ P+
Sbjct: 1016 ---------PPSPKGSPAATPFPKG-----------------ASTPPAATPPSPKGSPAA 1049
Query: 1732 TFSVVAGDLVLP-GSCQDPACSDKAP-GMEGTAALHGDSPARPQQAKEQP--GPERPIPA 1787
T LP G+ PA + +P G T +L G +P P P GP P P
Sbjct: 1050 T--------PLPKGAPTTPAATLPSPKGGPATPSLKG-APTPPAATPPSPKGGPATPSPK 1100
Query: 1788 GDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTS 1847
G ++PP P AP SP+ G L + P K AP
Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG---LATPPPKGAPTT------ 1151
Query: 1848 DETRGAEGTESSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAH 1907
T SP A P +PT A++ G + +PAA
Sbjct: 1152 -----PAATPPSPKGG----LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT- 1201
Query: 1908 AGLPPSAAEHIVSPSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPA 1967
PPS + +PS A+TP P P L+ + S + T + TP
Sbjct: 1202 ---PPSPKGGLATPSPKGAPTTPAATP--PSPKGGLA--TPSPKGAPTTPAATPPSPKGG 1254
Query: 1968 PPPPPPEVIPEPEVSTQP-------PPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSF 2020
P PPP+ P P +T P P G + V P P+ P P+
Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT--- 1311
Query: 2021 SAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISK 2080
P A+ + +G T P +
Sbjct: 1312 ---------------------------------PPAATPPSPKGSPGTPPPKGAPTPPAV 1338
Query: 2081 STLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQT 2140
+ S G P A P SS T +K+ P
Sbjct: 1339 TP--------------PSPKGTPTLPATTP------SSKGGPTTPSSKEGPTPPAATPSH 1378
Query: 2141 TKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPK 2200
P TPP P +P S K + SPA++ PL P P
Sbjct: 1379 KGGPAMTPP------SPKRGPAIP------------SPKGDPTSPAVI---PLSPKKAP- 1416
Query: 2201 AACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKG 2260
A P+ + EG P+ G PV K P T+AP+ G TPS S G PA
Sbjct: 1417 -ATPV---TREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPS-SKGDPTLPA-- 1469
Query: 2261 LSVRLEFDYSEDKSSWDNQQENPPPTKKIG------KKPVAKMPLRRPKM----KKTPEK 2310
+ PP K++ K P P+ P + +P++
Sbjct: 1470 --------------VTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKE 1515
Query: 2311 LDNTPASPPRSPAEPNDIPIAKGTYTFDIDK------------------WDDPNFNPFSS 2352
+ TP+S R P P ++K T K P P +
Sbjct: 1516 VPATPSS-RRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATP 1574
Query: 2353 TSKMQES-PKLPQQSYNFDPDTCDESVDPFKTS---SKTPSSPSKSPASFEIPASAMEAN 2408
+SK S P + +Y P + + P TS + P+ P+ +P S E +
Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPK 1634
Query: 2409 GVDGDGLNKPAKKKKTPLKTDTFRVK------KSPKRSPLSDPPS--QDPTPAATPETPP 2460
G P+ K +P + K ++ K P P+ ++ A PE+ P
Sbjct: 1635 GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTP 1694
Query: 2461 VISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYR 2520
+I+A + K + C P PS + +P L +
Sbjct: 1695 IITAPTRKGPQTKKSSATSPPIC------------PDPSAKNGSKGPLSTVAPAPLLPVQ 1742
Query: 2521 NSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEE 2580
K S P+ AP + + V P S S P S
Sbjct: 1743 KDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPL 1802
Query: 2581 TEALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKEL------EAMGLGTPSEAIEITA 2634
+ V T Q +P ES + + + EL E + G P +++ +
Sbjct: 1803 APSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNM 1862
Query: 2635 PEGSFASADALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQ-KLQEELEFAIMRIEALK 2693
P A PV+ E D E P L Q Q + A + A
Sbjct: 1863 PTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEI 1922
Query: 2694 LARQIALASRSHQDAKREAAHPTDVSISKTALYSRIGTAEV--EKPAGLLF--QQPDLDS 2749
++ A +S + K A +SK L G V K +LF +PD+
Sbjct: 1923 DEEPVSKAKQSRSEKKARKA------MSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYK 1976
Query: 2750 ALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAE-----YEKTIAQMIEDEQREK 2804
+ + I+ E ++ +D ++++ E K+ E E T +++E E+
Sbjct: 1977 S-PASDTYIVFGEAKI---EDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEE 2032
Query: 2805 SVSHQTVQQLVLEKEQALADLN 2826
V V+ +E + A+++
Sbjct: 2033 EVDETGVEVKDIELVMSQANVS 2054
Score = 100 bits (250), Expect = 2e-20
Identities = 255/1118 (22%), Positives = 364/1118 (32%), Gaps = 175/1118 (15%)
Query: 4 ENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDH-----RDASSIGSVGL--- 55
ENS S S T S PP + + TP SP ++ + V L
Sbjct: 838 ENSLSFQGSKDSPATTHSPTPP-SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFP 896
Query: 56 --GGFCTASESSASLDPCLVSPEVTEPRKDPQG---ARGPEGSLLP--SPPPSQEREHPS 108
G A + + +L SP+ P+G + P+G+ P + PPS + +
Sbjct: 897 KEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT 956
Query: 109 SSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDS-STPYQEI 167
S +A PP A+ +P+ GP T SP+ P P A A P+ + +TP +
Sbjct: 957 PSPKWAPTPP----AATPPSPKGGPATPSPKGAPTPPA-----ATPPSPKGGPATPSPKG 1007
Query: 168 AAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPV-PLREPMKAPLCGEGDQPGGFESQ 226
A P A PK G ++ F G P +P P P PL P G +
Sbjct: 1008 APTPPAVTPPSPK--GSPAATPFPKGASTPPAATPPSPKGSPAATPL------PKGAPTT 1059
Query: 227 EKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPR-- 284
A P + S++ P PAA + PM P P+P+
Sbjct: 1060 P---AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGG 1116
Query: 285 -ASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPH 343
A+ +G P A P G A A + + P
Sbjct: 1117 LATPPHKGAPTTP------------AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1164
Query: 344 AELPWGLPS-PALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLP 402
P G P+ PA P S K L T +G P T P
Sbjct: 1165 TPPPKGAPTTPAATPP---SPKGGLATPSPKGAPTT-------------------PAATP 1202
Query: 403 VSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVD 462
SP+ L TP+ + P + A+ P+ + +A P + + P A
Sbjct: 1203 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP--- 1259
Query: 463 AGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQ 522
P+G P A P +G P V PP PK
Sbjct: 1260 -------------------PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300
Query: 523 SHEVQP-GAPPPPLPKAPSESARGPPG--PTDGAKVHEDSTSPA-------VAKEGSRSP 572
P GAP PP P S +G PG P GA T P+ A S
Sbjct: 1301 PATSPPKGAPTPPAATPP--SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG 1358
Query: 573 GDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHS 632
G + +E P PP P + G S KR P + + P+S A P
Sbjct: 1359 GPTTPSSKEGPTPP-AATPSHKGGPAMTPPSPKRGPAIPSPK-GDPTSPAVIPLSPKKAP 1416
Query: 633 AQP-PRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGS 691
A P R+G A + G + A S P P G+PT+P A+ S
Sbjct: 1417 ATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLP--AVTPPS 1474
Query: 692 GLQPKCPDTLQSREG----------LGRMESFLTLESEKSDFPPTPVAEVAPKAQEGEST 741
+P P + + +G + S + P TP + P A
Sbjct: 1475 PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLL 1534
Query: 742 LEIRKMGSCDGEGL----LTSPDQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTALI 797
+ E L +T P + PA ++ P P + ++ +T
Sbjct: 1535 SKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE-----APATPSSKEASSPPAVT--- 1586
Query: 798 LDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKE 857
+G PS P E I A + E P+ P K A P G
Sbjct: 1587 -PSTYKGAPS-PKELLIPPAVTS--PSPKEAPTPPAVTPPSPE-----KGPATPAPKGTP 1637
Query: 858 TSP--SHPGFKDQGADSSQIHVPV---EPQEDNNLPTHGGQEQALGSELQSQLPKGTLSD 912
TSP + KD + + + PQ LP G AL L + P+ T
Sbjct: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKG-PTALKEVLVAPAPESTPII 1696
Query: 913 TPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRPEGACGDGQSSRVSP-PAADVLKD 971
T + +SS T P+ + G K G S V+P P V KD
Sbjct: 1697 TAPTRKGPQTKKSSATSPPICPDPSAKN----GSK--------GPLSTVAPAPLLPVQKD 1744
Query: 972 FSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQHEEACQRHPGASEAADGCSPLWGLS 1031
S K+ + +GP ++ A + E+ + AS +A P+
Sbjct: 1745 SSKTA--KGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPV---- 1798
Query: 1032 KREMASGNTGEAPPCQ---PDSVALLDAVPCLPALAPA 1066
+A PP Q P S L+ P P LAPA
Sbjct: 1799 SLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKP-LAPA 1835
Score = 97.1 bits (240), Expect = 2e-19
Identities = 317/1383 (22%), Positives = 443/1383 (32%), Gaps = 261/1383 (18%)
Query: 1036 ASGNTGEAPP----CQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQ 1091
AS N AP C P +A L P +P P SP + P P T+ D
Sbjct: 704 ASENCPVAPSPQNTCAP--LATLVLAPEIPKSVP-SPSLPPAGTPPGTKKVDGISH-TSA 759
Query: 1092 PVPAPQQKMEC-----WATSDAESPKLLASFPSAGEQGGEAGAAETG------GSAGAGD 1140
P EC A++ A S L + G + + +T GSAG
Sbjct: 760 LAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDT 819
Query: 1141 P-GKQQAPEKPGEATLSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDALLPARE 1199
P G +P P EA+ L G + S + A A+ P
Sbjct: 820 PIGNLSSPVSPVEASF----LPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSP 875
Query: 1200 LG-GIPRSTMDFSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSS 1258
G +P + +P PKE GP A P L + S++ + A +
Sbjct: 876 KGVTLPPKETPTPSVVNLPFPKE----GPATPAPKQAPALSMTSSSPKKARATPAPKGIP 931
Query: 1259 ADPRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKART 1318
A P G P PP A+ P P + G PA + G+P
Sbjct: 932 ASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGG-PATPSPKGAPTPPA 990
Query: 1319 TEGPVDSMPCLDRMPLLAKGKQATGEEKAATAPGA-------GAKASGEGMAGDAAGETE 1371
P KG AT K A P A G+ A+ G +
Sbjct: 991 ATPP------------SPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAA 1038
Query: 1372 GSMERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGEKA 1431
G P+ P G T + + + G P + P A P K
Sbjct: 1039 TPPSPKGSPAATPL--PKGAPTTPAATLPSPKGGP----ATPSLKGAPTPPAATPPSPKG 1092
Query: 1432 G----AGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPARLQVEKKQQLAGEAEISHL 1487
G + + A P P+ L PP P PA K LA
Sbjct: 1093 GPATPSPKGAPMPPAATPPSPKGGLATPPHKGA---PTTPAATPPSPKGGLATPPPKG-- 1147
Query: 1488 ALQDPASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYS 1547
A PA+ GL P G A PP+ P+G G A P +G +
Sbjct: 1148 APTTPAATPPSPKGGLA---TPPPKGAPTTPAATPPS------PKG-GLATPSPKGAPTT 1197
Query: 1548 QLERSRQELASGLPSPAATQELPVERAAAFQVA---PHSHGEEAVAQDRIPSGKQHQETS 1604
A+ PSP P + A A P G A PS K T
Sbjct: 1198 P--------AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT-----PSPKGAPTTP 1244
Query: 1605 ACDSPHGEDGPGDFAHTGVPGHVPRSTCAPS-------------PQREVLTVPEANSEPW 1651
A P + GP G P P + PS P V+T P P
Sbjct: 1245 AATPPSPKGGPATPPPKGAP--TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA 1302
Query: 1652 TLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGEVADTPLEPGKVAGAAGEAEGDITL 1711
T G P T + G+ TP PP G A TP
Sbjct: 1303 TSPPKGAPTPPAATP-----PSPKGSPGTP-PPKG--APTP------------------- 1335
Query: 1712 STAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAALHGDSPAR 1771
A T G TT + G P S + P P +G A+ SP R
Sbjct: 1336 -PAVTPPSPKGTPTLPATTPSSK---GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKR 1391
Query: 1772 PQQAKEQPGPERPIPAGDGKVCVSSPPEPDET-HDPKLQHLAPEELHTDRESPRPGPSML 1830
GP P P GD P P + P + A D P P L
Sbjct: 1392 --------GPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSL 1443
Query: 1831 PSVPKKDAPR------------VMDKVTSDETRGAE-----GTESSPVADDIIQPAAPAD 1873
P AP+ + VT + T SSP PA PA
Sbjct: 1444 KKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKK----APATPAP 1499
Query: 1874 LESPTL------------AASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSP 1921
+ +PTL A S D + +T L ++ + A L P A + SP
Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT-VPSP 1558
Query: 1922 SAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEV 1981
TP+ P P K+ + S+EA +P + TP A P P E++ P V
Sbjct: 1559 K---------KTPAIPTP-KEAPATPSSKEA-SSPPAVTPSTYKGA--PSPKELLIPPAV 1605
Query: 1982 STQPPPEEPGCGSETVPVPD-GPRSDSVEGSPFRPP------------SHSFSAVFDEDK 2028
++ P E P + T P P+ GP + + +G+P PP S +
Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATV 1665
Query: 2029 PIASSGTYNLDFDNIELVDTFQTLEPRAS---DAKNQEGKVNTRRKSTDSVPI------- 2078
P AS G L + P ++ A ++G T++ S S PI
Sbjct: 1666 PQASKG-LPAKKGPTALKEVLVAPAPESTPIITAPTRKGP-QTKKSSATSPPICPDPSAK 1723
Query: 2079 --SKSTLSR-----SLSLQ---ASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTK 2128
SK LS L +Q + G +S +P+ P++ ++ +A++ K
Sbjct: 1724 NGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLP 1783
Query: 2129 KPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALL 2188
KP S+ +PPV +L P + L S SP L+
Sbjct: 1784 KPESASV-------SAAPSPPVSLPLAPSPVPTLPPKQQFLPS------------SPGLV 1824
Query: 2189 EETPLEPAVGPKAACPLDSESAEGVVP--PASGGGRVQ----NSPPVGRKTLPLTTAPEA 2242
E+P +P P D + ++P P SGG Q N P +P+ T
Sbjct: 1825 LESPSKP------LAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAK 1878
Query: 2243 GEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRP 2302
VT ++ G +S + LE +D + QQ +I ++PV+K R
Sbjct: 1879 QPVTKNNKGSGTESDSDESVPELE---EQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRS 1935
Query: 2303 KMK 2305
+ K
Sbjct: 1936 EKK 1938
Score = 80.9 bits (198), Expect = 2e-14
Identities = 353/1667 (21%), Positives = 540/1667 (32%), Gaps = 315/1667 (18%)
Query: 69 DPCLVSPEVTEPRK-----DPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLA 123
+PC ++ T + P + GP ++ P+ P + P A P +A
Sbjct: 445 NPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMA------PVAPKEPSTQVA 498
Query: 124 SPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEG 183
+ P P P E N P + FP ++D T + P + P + G
Sbjct: 499 TTLRIPVSPPL---PDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFS-----PAQAG 550
Query: 184 QKSSFSFSSGIDQSPGMSPVPLREPMKAP----LCGEGDQPGGFESQEKEAAGGFP---- 235
+ + P + P+ P +P + P E+ + + G P
Sbjct: 551 LTTK--------KDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIG 602
Query: 236 -PAESRQGVASVQVTPEA-PAAAQQGTESSAVLEKSPL--KPMAPIP---QDPAPRASDR 288
PA S V + + G +S+ L KS L +A P DPA A
Sbjct: 603 KPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTT 662
Query: 289 ERGQGEAPPQYLTDDLEFLRACH--LPRSNS---------GAAPEAEVN---AASQESCQ 334
+G Y T FL P+++ P A N A S ++
Sbjct: 663 AKGTST----YTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTC 718
Query: 335 QPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTID-------VQGHPQ------TGMR 381
P+ + E+P +PSP+L P G + +D I V P+ +G
Sbjct: 719 APLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGAS 778
Query: 382 GTKPNQVVCVAAGGQPEG-GLPVSPE--------------------PSLLTPTEEAH-PA 419
T ++ P G+ VSP+ S ++P E + P
Sbjct: 779 ATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPE 838
Query: 420 SSLASFPAAQIPIAVEEPGSSSRES--VSKAGMPVSADAA----KEVVDAGLVGL----- 468
+SL+ + P P S + A P+S KE +V L
Sbjct: 839 NSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKE 898
Query: 469 ------ERQVSDLGSKGEHPE-----GDPGEVPAPSPQERG---EHLNTEQSHEVQPGVP 514
+Q L P+ P +PA SP +G T S + P P
Sbjct: 899 GPATPAPKQAPALSMTSSSPKKARATPAPKGIPA-SPSPKGAPTPPAATPPSPKGGPATP 957
Query: 515 PP---PLPKEQSHEVQPGAPPPPLPK-APSESARGPPGPTDGAKVHEDSTSPAVAKEGSR 570
P P P + G P P PK AP+ A PP P G +P
Sbjct: 958 SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017
Query: 571 SPGDSPGGK--EEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAES---R 625
SP SP + P P + +G + K P L P + +
Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLK 1077
Query: 626 DHPSSHSAQPPRKGGAGHTDGPH------SQTAEADASGL---PHKLGEEDP-VLPPVPD 675
P+ +A PP G T P + T + GL PHK P PP P
Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137
Query: 676 GAGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKA 735
G P+GA + P L + G + + PP+P +A +
Sbjct: 1138 GGLATPPPKGAPTTPAATPPSPKGGLATPPPKG-------APTTPAATPPSPKGGLATPS 1190
Query: 736 QEGESTLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLAADLG--L 793
+G T S +G L +P P A A P P G + G
Sbjct: 1191 PKGAPTTPAATPPS--PKGGLATPSPKGAPTTPA------ATPPSPKGGLATPSPKGAPT 1242
Query: 794 TALILDQDQQGIPSC-PGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPP 852
T +G P+ P +G A+ P L P + P ++ P
Sbjct: 1243 TPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV-----TPPSP 1297
Query: 853 ENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGT--- 909
+ G TSP +GA + P P+ P G + PKGT
Sbjct: 1298 KGGPATSP------PKGAPTPPAATPPSPKGSPGTPPPKGAPTP--PAVTPPSPKGTPTL 1349
Query: 910 LSDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRPE------GACGDGQSSRVSP 963
+ TP+S S + P+ + PA+ P+ GD S V P
Sbjct: 1350 PATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIP 1409
Query: 964 ------PAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQHEEACQRHPGA 1017
PA V ++ A S+ + P ++A A + +G + + P
Sbjct: 1410 LSPKKAPATPVTREG--AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDP-T 1466
Query: 1018 SEAADGCSPLWGLSKREMASGNTGEAPPCQPDSVALLDAVPCLPALAPASPGVTPTQDAP 1077
A SP + +++A+ ++ + P P + P LPA+ P+SP P
Sbjct: 1467 LPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM----GAPTLPAVIPSSPKEVPA---- 1518
Query: 1078 ETEACDETQEGRQQPVPAPQQKMECWATSDAESPKLLASFPSAGEQGGEAGAAETGGSAG 1137
T R+ P+ AP + T +PK A P A
Sbjct: 1519 -------TPSSRRDPI-APTATLLSKKTPATLAPK-EALIPPA----------------- 1552
Query: 1138 AGDPGKQQAPEKPGEATLSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDALLPA 1197
P ++ P P T E +T + +E AS A+ P+
Sbjct: 1553 MTVPSPKKTPAIP----------------TPKEAPATPSSKE--------ASSPPAVTPS 1588
Query: 1198 RELGGIPRSTMDFSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVS 1257
G P PKELL+ PP V +P E AV+
Sbjct: 1589 TYKG--------------APSPKELLI--PPAVTSPSP------------KEAPTPPAVT 1620
Query: 1258 SADPRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSP--K 1315
P +P P G P +SLK +P G +P QAS G P K
Sbjct: 1621 PPSPEKGPATPAPKGTPTSPPVTPSSLK--DSPTSPASVTCKMGATVP--QASKGLPAKK 1676
Query: 1316 ARTTEGPVDSMPCLDRMPLLA----KGKQATGEEKAATAPGAGAKASGEGMAGDAAGETE 1371
T V P + P++ KG Q T + A + P ++ G G +
Sbjct: 1677 GPTALKEVLVAPAPESTPIITAPTRKGPQ-TKKSSATSPPICPDPSAKNGSKGPLSTVAP 1735
Query: 1372 GSMERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREH---IAKIFEKPVLGALATPG 1428
+ P Q T+ G D S L P+ + A FEK P
Sbjct: 1736 APL----LPVQKDSSKTAKGKDASHSPKGPLAP-PESKASTPLTAAAFEK------VLPK 1784
Query: 1429 EKAGAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPARLQVEKKQQL--AGEAEISH 1486
++ + +A ++ PL P + PP LP+ P + + L A E E+
Sbjct: 1785 PESASVSAAPSPPVSLPLAPSPVPTLPP--KQQFLPSSPGLVLESPSKPLAPADEDELLP 1842
Query: 1487 LALQDPASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLREDERPEGPGAAWPGLEGQAY 1546
L +P S G+ ++ L K AG+P ++P G E
Sbjct: 1843 LIPPEPIS------GGVPFQSVLVNMPTPKS-AGIPVPTPSAKQPVTKNNKGSGTE---- 1891
Query: 1547 SQLERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEAVAQDR 1593
S + S EL + A TQ+ + AA P S +++ ++ +
Sbjct: 1892 SDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKK 1938
Score = 80.5 bits (197), Expect = 2e-14
Identities = 257/1153 (22%), Positives = 374/1153 (32%), Gaps = 158/1153 (13%)
Query: 1249 EDSGVKAVSSADPRAP--GESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPA 1306
EDSG A +S+ +SP P+G K GS P G +
Sbjct: 773 EDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTK--KGSAGPDTPIGNLSSPVSP 830
Query: 1307 VQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDA 1366
V+AS + + +G DS P P K A P A S +G+
Sbjct: 831 VEASFLPENSLSFQGSKDS-PATTHSP-------TPPSPKGAPTPSAVTPLSPKGVTLPP 882
Query: 1367 AGETEGSMERMGEPSQDP-----KQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVL 1421
S+ + P + P KQ + + +SS + A T P P
Sbjct: 883 KETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP 942
Query: 1422 GALATPGEKAGAGRSAVGKDLTRPLG-PEKLLDGPPGVDVTLLPAPPARLQVEKKQQLAG 1480
A P K G + T P P GP P PPA K G
Sbjct: 943 PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK---GG 999
Query: 1481 EAEISHLALQDPASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLREDERPEGPGAAWPG 1540
A S P + P G P G A PP+ P+G AA P
Sbjct: 1000 PATPSPKGAPTPPAVTPPSPKGSPAATPFP-KGASTPPAATPPS------PKGSPAATPL 1052
Query: 1541 LEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQVA---PHSHGEEAVAQDRIPSG 1597
+G + A+ LPSP P + A A P G A PS
Sbjct: 1053 PKGAPTTP--------AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPAT-----PSP 1099
Query: 1598 KQHQETSACDSPHGEDGPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLG 1657
K A P + G H G P P +T PSP+ + T P G
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPT-TPAAT-PPSPKGGLATPPPK----------G 1147
Query: 1658 GERRPGVTAGILEMRNALGNQSTPAP---PTGEVADTPLEPGKVAGAAGEAEGDITLSTA 1714
P T + G +TP P PT A P G +A + + A
Sbjct: 1148 APTTPAATPP-----SPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKG--------A 1194
Query: 1715 ETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAP-GMEGTAALHGDSPARPQ 1773
T A+ P+ G G+ PA + +P G T + G +P P
Sbjct: 1195 PTTPAATPPSPKGGLATPSP--------KGAPTTPAATPPSPKGGLATPSPKG-APTTPA 1245
Query: 1774 QAKEQP--GPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPSMLP 1831
P GP P P G ++PP AP SP+ GP+
Sbjct: 1246 ATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA--- 1302
Query: 1832 SVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADLESPTLAASSYHGDVVGQ 1891
+ P K AP T +G+ GT A P+ +PTL A++ G
Sbjct: 1303 TSPPKGAP-TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK--GG 1359
Query: 1892 VSTDLIAQSISPAAA---HAG----LPPSAAEHIVSPSAPAGDRVEASTPSCPD--PAKD 1942
+T + +P AA H G PPS PS A P P PA
Sbjct: 1360 PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATP 1419
Query: 1943 LSR--SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVS---------TQPPPEEPG 1991
++R ++ + TP + TPV AP P+ P S T P P+EP
Sbjct: 1420 VTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP 1479
Query: 1992 CGSETVPVPD---GPRSDSVEGSPFRP------PSHSFSAVFDEDKPIASSGTYNLDFDN 2042
+ P + + G+P P P + PIA + T
Sbjct: 1480 APKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP 1539
Query: 2043 IELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGN 2102
L + P + ++ K + P SK S ++ S + GA S
Sbjct: 1540 ATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPP-AVTPSTYKGAPS--- 1595
Query: 2103 PEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPP--------VKETQ 2154
P+ + + P S A + T PPS +K T P TP +K++
Sbjct: 1596 PKELLIPPAVTSPSPKEAPTPPAVT----PPSPEKGPATPAPKGTPTSPPVTPSSLKDSP 1651
Query: 2155 QEPDEESL-----VPSGENLASETKTESAKTE---GPSPALLEETPLEPAVGPKAACPLD 2206
P + VP K +A E P+P E TP+ A K
Sbjct: 1652 TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAP---ESTPIITAPTRKGPQTKK 1708
Query: 2207 SESAEGVV---PPASGGGRVQNSPPVGRKTLPL------TTAPEAGEVTPSDSGGQEDSP 2257
S + + P A G + S LP+ T + +P +S
Sbjct: 1709 SSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESK 1768
Query: 2258 AKGLSVRLEFD--YSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTP 2315
A F+ + +S+ + +PP + + PV +P ++ + +P + +P
Sbjct: 1769 ASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESP 1828
Query: 2316 ASPPRSPAEPNDI 2328
S P +PA+ +++
Sbjct: 1829 -SKPLAPADEDEL 1840
Score = 58.5 bits (140), Expect = 9e-08
Identities = 154/701 (21%), Positives = 230/701 (32%), Gaps = 124/701 (17%)
Query: 1827 PSMLPSVPKKDAPRVMDKVT---SDETRGAEGTESSPVADDIIQPAAPADLESPTLAASS 1883
P + PSV K P + +T S A SP I++ + A P +A
Sbjct: 375 PVVAPSVDK--GPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMP 432
Query: 1884 YHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAG--DRVEASTPSCPDPAK 1941
V V T + + A A VSP +G +E ++P+ A
Sbjct: 433 -----VSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAP 487
Query: 1942 DLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPE--PEVSTQPPPEEPGCGSETVPV 1999
+ ++ A T ++ P +PP P PE + V + P ++ +TVP
Sbjct: 488 VAPKEPSTQVA-------TTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKD---LQTVPA 537
Query: 2000 PDGPRSDSVEGSPFRPPSHSFSAVFDEDK-PIASSGTYNLDFDNIELVDTFQTLEPRASD 2058
S+EG+PF P + D P+ + N L P A+
Sbjct: 538 -------SLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATL 590
Query: 2059 AKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSG----------------- 2101
AK G+ K S+ S + ++ + G S+G
Sbjct: 591 AKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPL 650
Query: 2102 ---NPEAVA-LAPDAYSTGSSSASSTLKRTKK--PRPPSLKKKQTTKKP-----TETPPV 2150
+P VA ST +++AS L+ T P+ +K+ T P +E PV
Sbjct: 651 ESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPV 710
Query: 2151 KETQQE-----------PDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGP 2199
+ Q P+ VPS + T + K +G S + L P
Sbjct: 711 APSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGIS----HTSALAPVASS 766
Query: 2200 KAACPLDSESAEGVVPPASGGGRVQNSP-PVGRKTLPLTTAP--EAGEVTPSDSGGQEDS 2256
CP + A + +SP P+G P T P + G P G S
Sbjct: 767 PKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSS 826
Query: 2257 PAKGLSVRLEFDYSEDKSSWDNQQENP-------PPTKKIGKKPVAKMPLRRPKMKKTPE 2309
P + E+ S+ +++P PP+ K P A PL PK P
Sbjct: 827 PVSPVEASF---LPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLS-PKGVTLPP 882
Query: 2310 KLDNTPAS-----PPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQ 2364
K TP+ P PA P P + SS+ K + P+
Sbjct: 883 KETPTPSVVNLPFPKEGPATPAPKQA--------------PALSMTSSSPKKARATPAPK 928
Query: 2365 QSYNFDPDTCDESVDPFKTSSKTPSSPSKSPAS-----FEIPASAMEANGVDGDGLNKPA 2419
P P + TP SP PA+ P +A + G P
Sbjct: 929 -GIPASPSPKGAPTPP----AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPK 983
Query: 2420 KKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPT-PAATPETP 2459
P T SPK P + P PT PA TP +P
Sbjct: 984 GAPTPPAATPP-----SPKGGPATPSPKGAPTPPAVTPPSP 1019
Score = 47.0 bits (110), Expect = 3e-04
Identities = 207/956 (21%), Positives = 307/956 (32%), Gaps = 152/956 (15%)
Query: 1634 PSPQREVLTVPEANSEPWT--LDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGEVADT 1691
P PQ E +P +++ T L G P + + + NQ++P P +A T
Sbjct: 17 PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIAST 76
Query: 1692 PLEPGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPAC 1751
PLE ++G A + L TA +L + +A ++ P P
Sbjct: 77 PLEVPFPQSSSGTA---LPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTP-- 131
Query: 1752 SDKAPGMEGTAALHG--DSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQ 1809
S AP A H S A P P P + + +S+P P E L
Sbjct: 132 SSSAPLALVALAPHSVQKSSAFPPNLLTSP-PSVAVAESGSVITLSAPIAPSEP-KTNLN 189
Query: 1810 HLAPEELHTDRESPRPGPSMLPSVPK---------KDAPRVMDKVTSDETR--GAEGTES 1858
+ E + + +P P P ++ +VP + + + T T + +
Sbjct: 190 KVPSEVVPNPKGTPSP-PCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKD 248
Query: 1859 SPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSI-----SPAAAHAGLPP- 1912
+ ++ +I P P L S G V + L QS+ S A PP
Sbjct: 249 TTISSVLISPQNPGSL--------SLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPD 300
Query: 1913 ---SAAEHIVSPSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPP 1969
S H+ + V+ + P D + + S + T S ++ P
Sbjct: 301 FPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPL 360
Query: 1970 PPPPEVIPEP----EVSTQPPPEEPGCGSETVPVPDGPR--SDSVEGSPF------RPPS 2017
P EV+P V + P S P G + S SP P+
Sbjct: 361 PSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPN 420
Query: 2018 HSFSAVFDEDKPIASSGTYNLDFDN---IELVDTFQTLEPRASDAKNQEGKVNTRRKSTD 2074
++ P++S GT L N I T G ++ ++
Sbjct: 421 ATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSP 480
Query: 2075 SVPISKSTLSRSLSLQASD---FDGASSSGNPEAVALAPDA----YSTGSSSASSTLKRT 2127
+ + + S Q + + +PE + P + + T +
Sbjct: 481 AALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLE 540
Query: 2128 KKPRPPSLKKKQTTKKPTETPPVKET-QQEPDEESLVPSGENLASETKTESAKTEGP--- 2183
P P+ T K PT P V+ + P +S S E S T + K+ G
Sbjct: 541 GAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLP 600
Query: 2184 --SPALLEETPL-----------EPAVGPK---------------AACPLDSESAEGVVP 2215
PA +PL + GP AA PL+S GV P
Sbjct: 601 IGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAP 660
Query: 2216 PASGG-------------GRVQNSP---PVGRKTL-PLTTAPEAGEVTPSDSGGQED-SP 2257
+ G G V +P PV TL L P A E P Q +P
Sbjct: 661 TTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAP 720
Query: 2258 AKGLSVRLEFDYSEDKSSWDNQQENPPPTKKI-------GKKPVAKMPLRRP-------- 2302
L + E S S PP TKK+ PVA P P
Sbjct: 721 LATLVLAPEIPKSVPSPSLP-PAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASA 779
Query: 2303 --KMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESP 2360
K T L ++P SP + P K T D SS E+
Sbjct: 780 TASSKGTLTYLADSP-----SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEAS 834
Query: 2361 KLPQQSYNF-----DPDTCDESVDPFKTSSKTPSSPSK-SPASFEIPASAMEANGV---- 2410
LP+ S +F P T P + TPS+ + SP +P V
Sbjct: 835 FLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLP 894
Query: 2411 -DGDGLNKPAKKKKTPLKTDTFRVKK-----SPKRSPLSDPPSQDPT-PAATPETP 2459
+G PA K+ L + KK +PK P S P PT PAATP +P
Sbjct: 895 FPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSP 950
Score = 46.2 bits (108), Expect = 5e-04
Identities = 103/419 (24%), Positives = 143/419 (34%), Gaps = 97/419 (23%)
Query: 1970 PPPPEVIPEPEVSTQPPPEEP--------GCGSETVPVPDGPR------SDSVEGSPFRP 2015
P + +P+P+ T P G T+P P P S + + SPF
Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS 69
Query: 2016 PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDS 2075
PS S + P +SSGT L TF N G
Sbjct: 70 PSTIASTPLEVPFPQSSSGT-ALPLGTAPEAPTF---------LPNLIGP---------- 109
Query: 2076 VPISKSTLSRSLSLQASDFDGASSSGNPEA-VALAPDAYSTGSS--------------SA 2120
PIS + L+ + + A G SS P A VALAP + S+ +
Sbjct: 110 -PISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAE 168
Query: 2121 SSTLKRTKKPRPPSLKKKQTTKKPTE-TPPVKETQQEPDEESLVP-----------SG-E 2167
S ++ P PS K K P+E P K T P S VP SG
Sbjct: 169 SGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVA 228
Query: 2168 NLASETKTESAKTEGP------------SPALLEETPLEPAVGPKAACPLDSESAEGVVP 2215
+L T T + P SP L+ V P AA L ++S V
Sbjct: 229 SLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTS 288
Query: 2216 PASGGGRVQNSPP-----VGRKTLPL-----TTAPEAGEVTPSDSGGQEDSPAKGLSVRL 2265
G N+PP +G PL + G+ PS D K +SV
Sbjct: 289 SQKTAG--PNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPS---ALSDPTVKTISV-- 341
Query: 2266 EFDYSEDKSSWDNQQENPPP---TKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRS 2321
D+S +S+ +Q+ PP ++ VA P+ P + K P + + SP S
Sbjct: 342 --DHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGS 398
Score = 33.5 bits (75), Expect = 3.2
Identities = 70/350 (20%), Positives = 116/350 (33%), Gaps = 63/350 (18%)
Query: 36 QDTPGSPDHRDASSIGSVGLGGFCTASESSASLDPCLVSPEVTEPRKDPQGARGPEGSLL 95
++ P +P ++ASS +V + + + S L+ P VT P P+ A P
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTY----KGAPSPKELLIPPAVTSP--SPKEAPTPPAVTP 1621
Query: 96 PSPPPSQEREHPSSSMPFAECPPEGCLASPAAAPE-----DGPQTQSPRREPAPNAPGDI 150
PSP P + P SP + Q+ + PA P +
Sbjct: 1622 PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTAL 1681
Query: 151 AAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPG----MSPVPLR 206
A STP I A G + + S + S G ++P PL
Sbjct: 1682 KEVLVAPAPESTPI--ITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPL- 1738
Query: 207 EPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGV----------------ASVQVTP 250
P+ + + + G P ES+ ASV P
Sbjct: 1739 ----LPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAP 1794
Query: 251 EAPAAA-------------QQGTESS-AVLEKSPLKPMAPIPQDPAPRASDRERGQGEAP 296
P + QQ SS ++ +SP KP+AP +D E G P
Sbjct: 1795 SPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVP 1854
Query: 297 PQYLTDDLEFLRACHLP-----------RSNSGAAPEAEVNAASQESCQQ 335
Q + ++ ++ +P ++N G+ E++ + + E +Q
Sbjct: 1855 FQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQ 1904
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 92.4 bits (228), Expect = 6e-18
Identities = 305/1577 (19%), Positives = 499/1577 (31%), Gaps = 206/1577 (13%)
Query: 1071 TPTQDAPETEACDETQEGRQQPVPAP-QQKMECWATSDAESPKLLASFPSAGEQGGEAGA 1129
TP ++ E + T EG P P + + D+ +P + + + +
Sbjct: 894 TPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTST 953
Query: 1130 AETGGSAGAGDP----GKQQAPEKPGEATLSCGLLQTEHCLTSGEEAST---------SA 1176
T + P G P E T H L + EAST +
Sbjct: 954 PVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTP 1013
Query: 1177 LRESCQAEHPMASCQDALLPAR--ELGGIPRSTMDFSTHQAVPDPKELLLSGPPEVAAPD 1234
L S +A P + + +P G P + M ST L + P + + P
Sbjct: 1014 LTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPV 1073
Query: 1235 TPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPCPVGEPPLALENAASLKLFAGSLAPL 1294
T Y S++ ++AD + S G PL S +L S A
Sbjct: 1074 TTYSQASSSS------------TTADGTSMPTSTYSEGSTPLT-SVPVSTRLVVSSEAST 1120
Query: 1295 LQPGAAGGEIPAVQASSGSPKARTTEG-------PVDSMPCLDRMPLLAKGKQATGEEKA 1347
L IP ++ S T EG P + L MP+ ++
Sbjct: 1121 LSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTL 1180
Query: 1348 ATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPD 1407
+T P D+ + S E P + TS T E+ LT P
Sbjct: 1181 STTP------------VDSKTQVATSTEASSPP--PTAEVTSMPTSTPGERSTPLTSMPV 1226
Query: 1408 FREHIAK-----IFEKPV--LGALATPGEKAGAGRSAVGKDLTRPLGPE--KLLDGPPGV 1458
+A + PV + T E + + +A G L E LL P V
Sbjct: 1227 RHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIP-V 1285
Query: 1459 DVTLLPAPPARLQVEKKQQLAGEAEISHLALQDPASDKLLGPAGLTWERN---LPGAGVG 1515
TL+ +P A + G S+ P + T+ L V
Sbjct: 1286 STTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVN 1345
Query: 1516 KEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVERAA 1575
+ P S + + PS T + +
Sbjct: 1346 TTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVST 1405
Query: 1576 AFQVAPHSHGEEAVAQDRIPSGKQHQETSACDSPHGEDGPGDFAHTGVPGHVPRSTCAPS 1635
V+ + A D G E A SP +G +P P P
Sbjct: 1406 TPVVSSEASTLSATPVDTSTPGTTSAE--ATSSPTTAEG------ISIPTSTPSEGKTPL 1457
Query: 1636 PQREVLTVPEANSEPWTLDTLG-GERRPGVTAGILEMRNALGNQSTPAPPTGEVADTPLE 1694
V P ANSE TL T P VT+ A+ + TPA T TP E
Sbjct: 1458 KSIPVSNTPVANSEASTLSTTPVDSNSPVVTS------TAVSSSPTPAEGTSIAISTPSE 1511
Query: 1695 PGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDK 1754
G A +T T AS ++ TT +V + + +
Sbjct: 1512 -GSTA---------LTSIPVSTTTVASSEINSLSTTP--AVTSTPVTTYSQASSSPTTAD 1559
Query: 1755 APGMEGTAALHGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPE 1814
M+ + G +P P + + + ++P D K Q A
Sbjct: 1560 GTSMQTSTYSEGSTP-----LTSLPVSTMLVVSSEANTLSTTP------IDSKTQVTAST 1608
Query: 1815 ELHTDR---------ESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDI 1865
E + +P G +L S+P P + ++ T + +SPV
Sbjct: 1609 EASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVD--SNSPVITST 1666
Query: 1866 IQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPA 1925
++P E ++ S+Y G+ I +P A+ A S V S P
Sbjct: 1667 EVSSSPTPAEGTSMPTSTY---TEGRTPLTSITVRTTPVASSAISTLSTTP--VDNSTPV 1721
Query: 1926 GDRVEASTPSCPDPAKDLSRSSDSE---EAFETPESTTPVKAPPAPPPPPPEVIPEPEVS 1982
EA + + S+ SE P STTPV + A + V+
Sbjct: 1722 TTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVT 1781
Query: 1983 TQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDN 2042
T +E +P S+ + P SH+ A + ++ T +D ++
Sbjct: 1782 TSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVA----NSEASTLSTTPVDSNS 1837
Query: 2043 IELVDTFQTLEPRASDAKNQEGKVNTRRKST-DSVPISKSTLSRSLSLQASDFDGASSSG 2101
+ T + P ++ + + + S+P+S +T++ S + S +S+
Sbjct: 1838 PVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTP 1897
Query: 2102 NPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEES 2161
++ + SS ++ R +P S+ TT +E + T D +
Sbjct: 1898 VTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTL--ADTRT 1955
Query: 2162 LVPSGENLASETKTESAKTEGPSPALLE-ETPL-----------EPAVGPKAACPLDSE- 2208
V + + AS + T + T P+PA E TPL + P+D+
Sbjct: 1956 PVTT-YSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTST 2014
Query: 2209 ----SAEGVVPPASGGG-RVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSV 2263
S EG P + GG +Q S P +T PL P + + S G
Sbjct: 2015 PATTSTEGSSSPTTAGGTSIQTSTP-SERTTPLAGMPVSTTLVVSSEGN----------- 2062
Query: 2264 RLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLR-RPKMKKTPEKLDNTPASPPRSP 2322
L + K+ N E G P P + P L TP + P
Sbjct: 2063 TLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIP--LSTTPVASPE-- 2118
Query: 2323 AEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFK 2382
A T +D + +P +++++ SP +P + + T + P
Sbjct: 2119 --------ASTLSTTPVD-----SNSPVITSTEVSSSP-IPTEGTSMQTSTYSDRRTPL- 2163
Query: 2383 TSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPL 2442
+ P S + AS+ + L+ TP+ T++ + SP S
Sbjct: 2164 ---------TSMPVSTTVVASSAIST------LSTTPVDTSTPV-TNSTEARSSPTTSEG 2207
Query: 2443 SDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLS 2502
+ P+ P+ +TP T +S + T E T V + P ++ +
Sbjct: 2208 TSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGT 2267
Query: 2503 TFVNETKFSSPTEELDYRNSYEIEYMEKIG--SSLPQDDDAPKKQALYLMFDTSQESPVK 2560
+ T T S+ + ++ S+ P D + P F TS E+
Sbjct: 2268 SIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTP--------FTTSTEA--S 2317
Query: 2561 SSPVRMSESPTPCSGSS 2577
S P + P S SS
Sbjct: 2318 SPPPTAEGTSMPTSTSS 2334
Score = 80.1 bits (196), Expect = 3e-14
Identities = 284/1464 (19%), Positives = 472/1464 (32%), Gaps = 169/1464 (11%)
Query: 1174 TSALRESCQAEHPMASCQDALLP--ARELGGIPRSTMDFSTHQAVPDPKELLLSGPPEVA 1231
++ L S QA + + +P G P ++M ST + LL+ P E++
Sbjct: 185 STPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEIS 244
Query: 1232 APDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPCPVGEPPLALENAASLKLFAGSL 1291
P V +AQ + + + S ++ AP P+ PL S+ L S
Sbjct: 245 TP------VTISAQASSSPTTAEGPSLSNS-APSGGSTPLTRMPL------SVMLVVSSE 291
Query: 1292 APLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATGEEKAATAP 1351
A L A IP + ++ S T EG S+P +G A+T P
Sbjct: 292 ASTLSTTPAATNIPVITSTEASSSPTTAEGT--SIPT----STYTEGSTPLTSTPASTMP 345
Query: 1352 GAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREH 1411
A ++ S + +T + EPS P T++E + LT E
Sbjct: 346 VATSEMSTLSIT---PVDTSTLVTTSTEPSSLP---------TTAEATSMLTS--TLSEG 391
Query: 1412 IAKIFEKPVLGALATPGEKAGAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPARLQ 1471
+ PV L E + V E D ++ + P+
Sbjct: 392 STPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSE-- 449
Query: 1472 VEKKQQLAGEAEISHLALQD-PASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLREDER 1530
G ++ + + P + T + E + PPT +
Sbjct: 450 --------GSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSM 501
Query: 1531 PEGPGAAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEAVA 1590
P + P + + S +AS S +T PV+ + P + EA +
Sbjct: 502 P----TSTPSEGSTPLTSMSVSTMPVASSEASTLSTT--PVDTST-----PVTTSSEASS 550
Query: 1591 QDRIPSGKQHQETSACDSPHGEDGPGDFAHTGVPGHVPRSTCAPSPQRE-VLTVPEANSE 1649
P G ++ + V ++ P+ V T EA+S
Sbjct: 551 SSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSS 610
Query: 1650 PWTLDTLG------GERRPGVTAGILEMRNALGNQSTPAPPTGEVADTPLEPGKVAGAAG 1703
T + ER +T+ + ++++ T ++TP+ A ++
Sbjct: 611 STTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSS 670
Query: 1704 E-AEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDL-VLPGSCQDPACSDKAPGMEGT 1761
AEG ++ T+ TT S A L P P + T
Sbjct: 671 TTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPT 730
Query: 1762 AALHGDSPARPQQAKEQPGPERPIP----AGDGKVCVSSPPEPDETHDPKLQHLAPEELH 1817
A P P P+ +S+ P TH +
Sbjct: 731 TADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTT 790
Query: 1818 TDRES-----PRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGT---ESSPVADDIIQPA 1869
T+ S P G +L S+P P VTS E T +SPV +
Sbjct: 791 TEGTSMPISTPSEGSPLLTSIPVSITP-----VTSPEASTLSTTPVDSNSPVTTSTEVSS 845
Query: 1870 APADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRV 1929
+P E ++ S+Y + T L + +S + + V S P +
Sbjct: 846 SPTPAEGTSMPTSTY-----SEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNST 900
Query: 1930 EASTPSCPDPAKDLSRSSDSEEAF---ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPP 1986
EA + + S+ E + P+STTPV + A V V+T
Sbjct: 901 EARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTE 960
Query: 1987 PEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELV 2046
+E +P S+ P SH+ +A+S L ++
Sbjct: 961 ATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTL---------VANSEASTLSTTPVDSN 1011
Query: 2047 DTFQTLEPRASDAKNQEG-KVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEA 2105
T +S EG + T S S P+++ +S ++ + + ++ S P
Sbjct: 1012 TPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTM---VASSETSTLSTTPAD 1068
Query: 2106 VALAPDAYSTGSSSASSTLKRTKKPRPP-SLKKKQTTKKPTETPPVKETQQEPDEESLVP 2164
+ YS SSS S+T T P S T P T V E S P
Sbjct: 1069 TSTPVTTYSQASSS-STTADGTSMPTSTYSEGSTPLTSVPVSTRLV--VSSEASTLSTTP 1125
Query: 2165 SGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQ 2224
++ T TE++ SP E T + + + PL S + +S +
Sbjct: 1126 VDTSIPVTTSTEASS----SPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTL- 1180
Query: 2225 NSPPVGRKTLPLTTA-----PEAGEVT--PSDSGGQEDSPAKGLSVRLEFDYSEDKSSWD 2277
++ PV KT T+ P EVT P+ + G+ +P + VR S + S+
Sbjct: 1181 STTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLS 1240
Query: 2278 NQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTF 2337
T + T E ++ IP++ T
Sbjct: 1241 --------TSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVT- 1291
Query: 2338 DIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPAS 2397
P + +T + P + + P + + P T S+ + + P +
Sbjct: 1292 ------SPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVN 1345
Query: 2398 FEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPE 2457
+ AS+ + L+ TP+ T T SP S + P+ +P+ TP
Sbjct: 1346 TTLVASSAISI------LSTTPVDNSTPVTTST-EACSSPTTSEGTSMPNSNPSEGTTPL 1398
Query: 2458 TP-PVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLST--FVNETKFSSPT 2514
T PV + V +++ L+ T P D ST + SSPT
Sbjct: 1399 TSIPVSTTPVVSSEASTLSAT--------------------PVDTSTPGTTSAEATSSPT 1438
Query: 2515 --EELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYL-MFDTSQESPVKSSPVRMSESPT 2571
E + S E + S + +A L SPV +S +S SPT
Sbjct: 1439 TAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTS-TAVSSSPT 1497
Query: 2572 PCSGSSFEETEALVNTAAKNQHPV 2595
P G+S + + A PV
Sbjct: 1498 PAEGTSIAISTPSEGSTALTSIPV 1521
Score = 79.0 bits (193), Expect = 7e-14
Identities = 203/1043 (19%), Positives = 347/1043 (33%), Gaps = 143/1043 (13%)
Query: 1608 SPHGEDGPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAG 1667
SP DG + +P PR P V T A+SE TL T + R VT
Sbjct: 1907 SPTTADG------SSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTY 1960
Query: 1668 ILEMRNALGNQSTPAPPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQACASGDLPEA 1727
+Q++ +P T + P +EG ST T S L +
Sbjct: 1961 ---------SQASSSPTTADGTSMP--------TPAYSEG----STPLTSMPLSTTLVVS 1999
Query: 1728 GTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAALHGDSPA-RPQQAKEQPGPERPIP 1786
T S D P + S +P G ++ +P+ R P +
Sbjct: 2000 SEASTLSTTPVDTSTPATTSTEGSS--SPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVV 2057
Query: 1787 AGDGKVCVSSPPEPDE--THDPKLQHLAPEELHTDRES-PRPGPSMLPSVPKKDAPRVMD 1843
+ +G ++P + T+ + A E + S P G +L S+P P
Sbjct: 2058 SSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASP 2117
Query: 1844 KVTSDETRGAEGTESSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISP 1903
+ ++ T + +SPV ++P E ++ S+Y T L + +S
Sbjct: 2118 EASTLSTTPVDS--NSPVITSTEVSSSPIPTEGTSMQTSTY-----SDRRTPLTSMPVST 2170
Query: 1904 AAAHAGLPPSAAEHIVSPSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAF---ETPESTT 1960
+ + + V S P + EA + + S+ SE + P ST
Sbjct: 2171 TVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTM 2230
Query: 1961 PVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSF 2020
PV A V V+T +E +P S+ P SH+
Sbjct: 2231 PVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTL 2290
Query: 2021 SAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEG-KVNTRRKSTDSVPIS 2079
+A+S L ++ F T +S EG + T S + P++
Sbjct: 2291 ---------VANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLT 2341
Query: 2080 KSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQ 2139
+ +S ++ + F+ ++ S P + YS SS ++ + S
Sbjct: 2342 RMPVSTTM---VASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTP 2398
Query: 2140 TTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGP 2199
T P T PV ++ + V + + + T+ S+ T ++ P E P
Sbjct: 2399 LTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTT-P 2457
Query: 2200 KAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAK 2259
A+ P+ + P S ++ PV T P+TT+ EA SP
Sbjct: 2458 LASMPVST------TPVVSSEAGTLSTTPVDTST-PMTTSTEASS-----------SPTT 2499
Query: 2260 GLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPK---MKKTPEK-----L 2311
+ + + + S+ + PV+ P+ P+ + TP +
Sbjct: 2500 AEDIVVPISTASEGSTL------------LTSIPVSTTPVASPEASTLSTTPVDSNSPVV 2547
Query: 2312 DNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDP 2371
+T S + AE +P + TY+ P S + P ++
Sbjct: 2548 TSTEISSSATSAEGTSMPTS--TYS--------EGSTPLRSMP-VSTKPLASSEASTLST 2596
Query: 2372 DTCDESVDPFKTSSKTPSSPSK--------------SPASFEIPASAMEANGVDGDGLNK 2417
D S+ P TS++T SSP+ S + I S M + L+
Sbjct: 2597 TPVDTSI-PVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLST 2655
Query: 2418 PAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVT 2477
+T + T T SP + S P+ P +TP T ++S + A E T
Sbjct: 2656 TPVDTRTLVTTST-GTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLST 2714
Query: 2478 NQKWTCMTVDLEADKQDYP-----------QPSDLSTFVNETKFSS---PTEELDYRNSY 2523
T V A+ P PSD ST + S+ + E ++
Sbjct: 2715 TPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTT 2774
Query: 2524 EIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQES-------PVKSSPVRMSESPTPCSGS 2576
++ + +S + + T E+ PV +PV SE+ T +
Sbjct: 2775 AVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTP 2834
Query: 2577 SFEETEALVNTAAKNQHPVPRGL 2599
T +T A + G+
Sbjct: 2835 VDTSTPVTTSTKASSSPTTAEGI 2857
Score = 79.0 bits (193), Expect = 7e-14
Identities = 215/1042 (20%), Positives = 349/1042 (33%), Gaps = 116/1042 (11%)
Query: 1603 TSACDSPHGEDGPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRP 1662
T A SP +G T +P P P V T P +SE TL T +
Sbjct: 2432 TEASSSPTTAEG------TSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTST 2485
Query: 1663 GVTAGILEMRNALGNQSTPAPPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQACASG 1722
+T +++ +P T E P+ A E +T T AS
Sbjct: 2486 PMTTS---------TEASSSPTTAEDIVVPIS------TASEGSTLLTSIPVSTTPVAS- 2529
Query: 1723 DLPEAGTTRTFSVVAGDLVLPGS-CQDPACSDKAPGMEGTAALHGDSPARPQQAKEQPGP 1781
PEA T T V + V+ + A S + M + G +P R P
Sbjct: 2530 --PEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLR-----SMPVS 2582
Query: 1782 ERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPSMLPSVPKKDAPRV 1841
+P+ + + ++P + + + D P PS + +
Sbjct: 2583 TKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVST 2642
Query: 1842 MDKVTSDETRGAEGTESSPVADDIIQPAAPADLESPTLA-ASSYHGDVVGQ--------- 1891
M +S+ A ++PV + + SPT A SS G+
Sbjct: 2643 MPVASSE----ASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNIL 2698
Query: 1892 VSTDLIAQS----ISPAAAHAGLP-PSAAEHIVSPSAPAGDRVEASTPSCPD-PAKDLSR 1945
VST L+A S +S P ++AE SP+ G + STPS P +
Sbjct: 2699 VSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILV 2758
Query: 1946 SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEP---EVSTQPP--PEEPGCGSETVPVP 2000
S+ + E +T P E P EV++ P P E ++PV
Sbjct: 2759 STLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVN 2818
Query: 2001 DGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYN---LDFDNIELVDTFQTLEPRAS 2057
P + S G+ P + + V K +S T + T T P ++
Sbjct: 2819 HTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVST 2878
Query: 2058 D--AKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYST 2115
A ++ ++T T S+P++ ST S A S+ + + L ST
Sbjct: 2879 TPVASSEASTLSTTPVDT-SIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVST 2937
Query: 2116 ------GSSSASSTLKRTKKPRPPSLKKKQT------TKKPTETPPVKETQQEPDEESLV 2163
+S+ S+T T+ P S + + T P TP + T S +
Sbjct: 2938 VPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTM 2997
Query: 2164 PSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRV 2223
P + AS A T P E + P P+ + S EG P S V
Sbjct: 2998 PVASSEASTLSRTPADTSTPVTTSTEASS-SPTTAEGTGIPISTPS-EGSTPLTSIP--V 3053
Query: 2224 QNSPPVGRKTLPLTTAP--EAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQE 2281
+P + L+T P V S +PA+G S+ + YSE +
Sbjct: 3054 STTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPIS-TYSEGSTPLTGVPV 3112
Query: 2282 NPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPAS------PPRSPAEPNDIPIAKGTY 2335
+ P ++ P+ T + ++P + P +P+E +
Sbjct: 3113 STTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVS 3172
Query: 2336 TFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSP 2395
T + +D S + + S + + T + + P T S+ + + P
Sbjct: 3173 TMLVVSSEDSTL----SATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVP 3228
Query: 2396 ASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAAT 2455
S P ++ EA+ L+ TPL T T SP + + P+ P+ +T
Sbjct: 3229 VS-NTPVASSEASI-----LSTTPVDSNTPLTTST-EASSSPPTAEGTSMPTSTPSEGST 3281
Query: 2456 PETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNET--KFSSP 2513
P T +S A+ E T T V + P +D ++ T + S+P
Sbjct: 3282 PLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTP 3341
Query: 2514 TEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPC 2573
+ + + + S+ P D P TS E+ S SPT
Sbjct: 3342 LTNMSFSTTPVVSSEASTLSTTPVDTSTP--------VTTSTEA---------SLSPTTA 3384
Query: 2574 SGSSFEETEALVNTAAKNQHPV 2595
G+S + T PV
Sbjct: 3385 EGTSIPTSSPSEGTTPLASMPV 3406
Score = 75.1 bits (183), Expect = 1e-12
Identities = 193/901 (21%), Positives = 298/901 (33%), Gaps = 140/901 (15%)
Query: 1608 SPHGEDGPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAG 1667
S G P T +P P P V TVP A SE TL T + R VT
Sbjct: 2903 STEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTS 2962
Query: 1668 ILEMRNALGNQSTPAPPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQACASGDLPEA 1727
+++ +P T E P+ GE +T + T AS +
Sbjct: 2963 A---------EASSSPTTAEGTSMPIS------TPGERRTPLTSMSVSTMPVASSE---- 3003
Query: 1728 GTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAALHGDSPARPQQAKEQPGPERPIPA 1787
T S D P + A S EGT G + P + P IP
Sbjct: 3004 --ASTLSRTPADTSTPVTTSTEASSSPTTA-EGT----GIPISTPSEGST---PLTSIPV 3053
Query: 1788 GDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTS 1847
V + PE + +P T+ S P P+ S+P +T
Sbjct: 3054 STTPVAI---PEASTLSTTPVDSNSPVVTSTEVSSS-PTPAEGTSMPISTYSEGSTPLTG 3109
Query: 1848 DETRGAEGTESSPVADDIIQPAA--PADLESPTLAASSYHGDVVGQVSTDLIAQSISPAA 1905
++PV I + P D +P ++ H T + + S +
Sbjct: 3110 VPV------STTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGS 3163
Query: 1906 AHAGLPPSAAEHIVSPSAPAGDRVEASTP---SCPDPAKDLSRSSDSEEAFETPEST--- 1959
P + +VS D ++TP S P + SS + E P ST
Sbjct: 3164 TPLTYMPVSTMLVVSSE----DSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSE 3219
Query: 1960 --TPVKAPPAPPPP----PPEVIPEPEVSTQPPPEEPGCGSETVPVPDG---PRSDSVEG 2010
TP+ + P P ++ V + P S + P +G P S EG
Sbjct: 3220 GMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEG 3279
Query: 2011 SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEG-KVNTR 2069
S +++ +ASS T L + T +S +G + T
Sbjct: 3280 ST------PLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTS 3333
Query: 2070 RKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKK 2129
S S P++ + S + + + AS+ P ST +S + +T + T
Sbjct: 3334 TYSEGSTPLTNMSFSTTPVVSSE----ASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSI 3389
Query: 2130 PRP-PSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALL 2188
P PS P T PV E + S P N T TE++ SP +
Sbjct: 3390 PTSSPSEGTTPLASMPVSTTPV--VSSEVNTLSTTPVDSNTLVTTSTEASS----SPTIA 3443
Query: 2189 EETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTA------PEA 2242
E T L + + + PL S P AS ++ PV T P+TT+ P
Sbjct: 3444 EGTSLPTSTTSEGSTPL-SIMPLSTTPVASSEASTLSTTPVDTST-PVTTSSPTNSSPTT 3501
Query: 2243 GEVT--PSDSGGQEDSPAKGLSVRLEFDYSEDKSSWD-------------NQQENPPPTK 2287
EVT P+ + G+ +P + V S + S+ +Q + P T
Sbjct: 3502 AEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATL 3561
Query: 2288 KIGKKPVAKMPLRRPK--------MKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDI 2339
+ V M + P M + + ++ AS P +P+ P+ T +
Sbjct: 3562 Q-----VTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNST 3616
Query: 2340 DKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDES-------VD---PFKTSSKTPS 2389
+ P S+ S++ S L + T E+ VD P TS++ S
Sbjct: 3617 PTPPEVITLPMSTPSEV--STPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSS 3674
Query: 2390 SP--------------SKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKK 2435
SP S +P S +G L+ P+ TP+ T T +
Sbjct: 3675 SPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISS 3734
Query: 2436 S 2436
S
Sbjct: 3735 S 3735
Score = 67.0 bits (162), Expect = 3e-10
Identities = 220/1045 (21%), Positives = 342/1045 (32%), Gaps = 159/1045 (15%)
Query: 1603 TSACDSPHGEDGPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRP 1662
T A SP +G T +P P P V ANSE TL T +
Sbjct: 959 TEATSSPTTAEG------TSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNT 1012
Query: 1663 GVTAGILEMRNALGNQSTPAPPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQACASG 1722
+T +++ PPT E P + +EG ST T+ S
Sbjct: 1013 PLTTS---------TEASSPPPTAEGTSMP--------TSTPSEG----STPLTRMPVST 1051
Query: 1723 DLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAALHGDSPARPQQAKEQPGPE 1782
+ + T T S D P + A S +GT+ P
Sbjct: 1052 TMVASSETSTLSTTPADTSTPVTTYSQASSSSTTA-DGTSMPTSTYSEGSTPLTSVPVST 1110
Query: 1783 RPIPAGDGKVCVSSPPEPD----ETHDPKLQHLAPEELHTDRESPRPGPSMLPSVP---- 1834
R + + + ++P + + + E P G + L S+P
Sbjct: 1111 RLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTT 1170
Query: 1835 ---KKDAPRVMDKVTSDETRGAEGTESS---PVADDIIQPAA-PADLESPTLAASSYHGD 1887
+A + +T+ A TE+S P A+ P + P + +P + H
Sbjct: 1171 LVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTP 1230
Query: 1888 VVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEASTPSCPDPAKDLSRSS 1947
V ++ L S SP + SA E SP+ G + ST S + + L+
Sbjct: 1231 VASSEASTL---STSPVDTSTPVTTSA-ETSSSPTTAEGTSLPTSTTS--EGSTLLTSIP 1284
Query: 1948 DSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDS 2007
S +PE++T + P P V+ EVS+ P P E G+ P S
Sbjct: 1285 VSTTLVTSPEASTLLTTPVDTKGP---VVTSNEVSSSPTPAE---GTSM------PTSTY 1332
Query: 2008 VEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVN 2067
EG R P S +ASS L ++ T S EG
Sbjct: 1333 SEG---RTPLTSIPV---NTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSM 1386
Query: 2068 TRRKSTD------SVPISKSTL--SRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSS 2119
++ S+P+S + + S + +L A+ D S+ G A A + + G S
Sbjct: 1387 PNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVD-TSTPGTTSAEATSSPTTAEGISI 1445
Query: 2120 ASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAK 2179
+ST PS K P PV ++ + V S + + T S+
Sbjct: 1446 PTST---------PSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSP 1496
Query: 2180 TEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTA 2239
T PA G A SE + + V +S T P T+
Sbjct: 1497 T--------------PAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTS 1542
Query: 2240 PEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDN----------QQENPPPTKKI 2289
VT + A G S++ YSE + + + N T I
Sbjct: 1543 TP---VTTYSQASSSPTTADGTSMQTS-TYSEGSTPLTSLPVSTMLVVSSEANTLSTTPI 1598
Query: 2290 GKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNP 2349
K T E T ++P IP++ P +
Sbjct: 1599 DSKTQVTASTEASS-STTAEGSSMTISTPSEGSPLLTSIPVSTTPVA-------SPEAST 1650
Query: 2350 FSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKT--SSKTPSSPSKSPASFEIPASAMEA 2407
S+T SP + + P + + P T +TP + S + + + +SA+
Sbjct: 1651 LSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLT-SITVRTTPVASSAIST 1709
Query: 2408 NGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETP-PVISAVV 2466
L+ TP+ T T + SP S + P+ P+ TP T PV + V
Sbjct: 1710 -------LSTTPVDNSTPVTTST-EARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPV 1761
Query: 2467 HATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETK--FSSPT--EELDYRNS 2522
+++ L+ T P D ST V + SSPT E S
Sbjct: 1762 LSSEASTLSAT--------------------PIDTSTPVTTSTEATSSPTTAEGTSIPTS 1801
Query: 2523 YEIEYMEKIGSSLPQDDDAPKKQALYLMFD-TSQESPVKSSPVRMSESPTPCSGSSFEET 2581
E M + S+ +A L SPV +S +S SPTP G+S +
Sbjct: 1802 TLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTA-VSSSPTPAEGTSIATS 1860
Query: 2582 EALVNTAAKNQHPVPRGLAPNQESH 2606
+ A PV + E++
Sbjct: 1861 TPSEGSTALTSIPVSTTTVASSETN 1885
Score = 62.0 bits (149), Expect = 8e-09
Identities = 153/724 (21%), Positives = 249/724 (34%), Gaps = 92/724 (12%)
Query: 1846 TSDETRGAEGTESSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLI---AQSIS 1902
T A GT S+ V + + + + E ++ SS D G ST + +++ S
Sbjct: 61 TGSAANTATGTTSTNVVEPRMYLSCSTNPEMTSIE-SSVTSDTPGVSSTRMTPTESRTTS 119
Query: 1903 PAAAHAG-LPPSAAEHIVSPSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTP 1961
+ + + L PS+ E SP+ P G V STPS S S AF ST P
Sbjct: 120 ESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPS--------EESISSTMAF---VSTAP 168
Query: 1962 VKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDG-PRSDSVEGSPFRPPSHSF 2020
+ + A +V ++ST S T P P+S + EGS P S
Sbjct: 169 LPSFEAYTSLTYKV----DMSTPLTTSTQASSSPTTPESTTIPKSTNSEGS---TPLTSM 221
Query: 2021 SAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEG-KVNTRRKSTDSVPIS 2079
A +ASS L +E+ +S EG ++ S S P++
Sbjct: 222 PA---STMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLT 278
Query: 2080 KSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLK-KK 2138
+ LS L + + AS+ A P ST +SS+ +T + T P +
Sbjct: 279 RMPLSVMLVVSSE----ASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGST 334
Query: 2139 QTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVG 2198
T P T PV ++ + V + + + T+ S T + ++L T L
Sbjct: 335 PLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTST-LSEGST 393
Query: 2199 PKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGE--VTPSDSGGQEDS 2256
P P+ + + AS ++ PV KT +TTA EA T D+ +
Sbjct: 394 PLTNMPVST------ILVASSEASTTSTIPVDSKTF-VTTASEASSSPTTAEDTSIATST 446
Query: 2257 PAKGLSVRLEFDY-------------------SEDKSSWDNQQENPPPTKKIGKKPVA-- 2295
P++G + S+ + + + + PPT ++ P +
Sbjct: 447 PSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTP 506
Query: 2296 ---KMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSS 2352
PL + P + ++ AS + P+ + + P S+
Sbjct: 507 SEGSTPLTSMSVSTMP--VASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTST 564
Query: 2353 TSK-------MQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAM 2405
S+ M S +L S T + F T+S SS S + +P S
Sbjct: 565 PSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTY 624
Query: 2406 EANGV---------------DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDP 2450
G + L+ TP+ T T S S P S
Sbjct: 625 SERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTS-TY 683
Query: 2451 TPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKF 2510
T +TP T ++ + A+ E T T V + P +D ++ T
Sbjct: 684 TEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPS 743
Query: 2511 SSPT 2514
T
Sbjct: 744 EGST 747
Score = 51.2 bits (121), Expect = 1e-05
Identities = 183/954 (19%), Positives = 290/954 (30%), Gaps = 134/954 (14%)
Query: 1587 EAVAQDRIPSGKQHQETSACDSPHGEDGPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEA 1646
EA R P+ T S P TG+P P P V T P A
Sbjct: 3003 EASTLSRTPADTS---TPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVA 3059
Query: 1647 NSEPWTLDTLG-GERRPGVTAGILEMRNALGNQSTPAPPTGEVADTPLEPGKVAGAAGEA 1705
E TL T P VT+ + + TPA T T E +
Sbjct: 3060 IPEASTLSTTPVDSNSPVVTS------TEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVS 3113
Query: 1706 EGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAALH 1765
+T S T + D TT T + + M +
Sbjct: 3114 TTPVTSSAISTLSTTPVDTSTPVTTST------------EAHSSPTTSEGTSMPTSTPSE 3161
Query: 1766 GDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPE---PDETHDPKLQHLAPEELHTDRES 1822
G +P P + + + ++P + P T E +
Sbjct: 3162 GSTP-----LTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTST 3216
Query: 1823 PRPGPSMLPSVPKKDAPRVMDKVT----------SDETRGAEGTESSPVADDIIQPAAPA 1872
P G + L SVP + P + + + T E + S P A+ P +
Sbjct: 3217 PSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTP 3276
Query: 1873 DLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEAS 1932
S L + V T + S +PA P S S P D
Sbjct: 3277 SEGSTPLTSMPVSTTTVASSETSTL--STTPADTST---PVTTYSQASSSPPIADGTSMP 3331
Query: 1933 TPSCPDPAKDLSRSSDSEEAFETPE----STTPV-KAPPAPPPPPPEVIPEPEVSTQPPP 1987
T + + + L+ S S + E STTPV + P + P T P
Sbjct: 3332 TSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPT 3391
Query: 1988 EEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVD 2047
P G T P+ P S + P+ SS L ++
Sbjct: 3392 SSPSEG--TTPLASMPVSTT---------------------PVVSSEVNTLSTTPVDSNT 3428
Query: 2048 TFQTLEPRASDAKNQEG-KVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAV 2106
T +S EG + T S S P+S LS + + AS+
Sbjct: 3429 LVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSE----ASTLSTTPVD 3484
Query: 2107 ALAPDAYSTGSSSASSTLKRTKKPRPPSLK-KKQTTKKPTETPPVKETQQEPDEESLVPS 2165
P S+ ++S+ +T + T P + + T P T PV ++ + V S
Sbjct: 3485 TSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDS 3544
Query: 2166 GENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDS--------ESAEGVVPPA 2217
+ S ++ S SPA L+ T + + + + L + S+E P
Sbjct: 3545 NTFVTSSSQASS------SPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPST 3598
Query: 2218 SGGGR--------VQNSPPVGRK--TLPLTTAPEAG-----------EVTPSDSGGQEDS 2256
R NS P + TLP++T E VT S++G
Sbjct: 3599 PSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTL 3658
Query: 2257 PAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPA 2316
P + + P T G P+ MP+ ++ + +TP+
Sbjct: 3659 PVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPS 3718
Query: 2317 SPPRSPAEPNDIPIAKGTYTFDIDKWD---DPNFNPFSSTSKMQESP--KLPQQSYNFDP 2371
+P + I+ T D + +T + +P + P+ S P
Sbjct: 3719 VVTSTPVTTSTEAISSSA-TLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIP 3777
Query: 2372 DTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTF 2431
T+S+ SSP+ + +P S T +
Sbjct: 3778 SVYTSM--SMTTASEGSSSPTTLEGTTTMPMSTTSERST-----------LLTTVLISPI 3824
Query: 2432 RVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT 2485
V + S LS PP TP T S T ++++T+++ T +T
Sbjct: 3825 SVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVT-TIRISITSERSTPLT 3877
Score = 45.4 bits (106), Expect = 8e-04
Identities = 153/808 (18%), Positives = 251/808 (31%), Gaps = 137/808 (16%)
Query: 666 EDPVLPPVPDGAGEP--TVPEGAIWEGSGLQPKCP----DTLQSREGLGRMESFLTLESE 719
ED P P+G P T E +I P + S M + LT ++
Sbjct: 134 EDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQ 193
Query: 720 KSDFPPTPVAEVAPKAQEGESTLEI-------RKMGSCDGEGLLTSPDQPRGPACDASRQ 772
S P TP + PK+ E + + K+ S + LLT+P + P +++
Sbjct: 194 ASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQA 253
Query: 773 EFHAGVPHPPQGENLAADLGLT---------ALILDQDQQGIPSCPGEGWIRGAASEWPL 823
P N A G T L++ + + + P AA+ P+
Sbjct: 254 SSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTP-------AATNIPV 306
Query: 824 LSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSPSHPGFKDQGADSSQIHVPVEPQE 883
++S + TSI G S P A S + + P +
Sbjct: 307 ITSTEASSSPTTAEGTSI------PTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVD 360
Query: 884 DNNLPTHGGQEQAL----------------GSELQSQLPKGTL----SDTPTSSPTDMVW 923
+ L T + +L GS + +P T+ S+ T+S +
Sbjct: 361 TSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDS 420
Query: 924 ESSLTEESEL-SAPTRQKLPALGEKRPEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKE 982
++ +T SE S+PT + ++ P +G + S P + S A N S
Sbjct: 421 KTFVTTASEASSSPTTAEDTSIATSTP----SEGSTPLTSMPVSTTPVASSEASNLSTT- 475
Query: 983 TCCTGQGPNKSQQALADALEEGSQHEEACQRHPGASEAADGCSPLWGLSKREMASGNTGE 1042
P S+ + + E S A S ++G +PL +S M
Sbjct: 476 -------PVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTM------- 521
Query: 1043 APPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQQKMEC 1102
P + L P + TP + E + T EG P P +
Sbjct: 522 --PVASSEASTLSTTPVDTS--------TPVTTSSEASSSSTTPEGTSIPTSTPSEGSTP 571
Query: 1103 WATSDAESPKLLASFPSA-----GEQGGEAGAAETGGSAGAGDPGKQQAPEKPGEATLSC 1157
+ +++S S + + S+ G E +
Sbjct: 572 LTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTI 631
Query: 1158 GLLQTEHCLTSGEEAST---------SALRESCQAEHPMASCQDALLPAREL--GGIPRS 1206
+ L + EAST + + S +A + + +P G P +
Sbjct: 632 TSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLT 691
Query: 1207 TMDFSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRA-PG 1265
+M +T L + P + + P T A S A ++ P + P
Sbjct: 692 SMPVNTTLVASSEASTLSTTPVDTSTPVT--------TSTEASSSPTTADGASMPTSTPS 743
Query: 1266 ESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTEG---- 1321
E P+ P+ S L S A L ++ S TTEG
Sbjct: 744 EGSTPLTSMPV------SKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMP 797
Query: 1322 ---PVDSMPCLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMG 1378
P + P L +P+ + +T P D+ S E
Sbjct: 798 ISTPSEGSPLLTSIPVSITPVTSPEASTLSTTP------------VDSNSPVTTSTEVSS 845
Query: 1379 EPSQDPKQGTSGGVDTSSEQIATLTGFP 1406
P+ P +GTS T SE LT P
Sbjct: 846 SPT--PAEGTSMPTSTYSEGRTPLTSMP 871
Score = 41.6 bits (96), Expect = 0.012
Identities = 280/1440 (19%), Positives = 442/1440 (30%), Gaps = 201/1440 (13%)
Query: 13 TLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSASLD--- 69
TLS S P S + G+ S GS L ++ + AS +
Sbjct: 1827 TLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNT 1886
Query: 70 ----PCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAE---CPPEGCL 122
P + S VT + +GS +P+ P + R P +S+P + E
Sbjct: 1887 LSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRP-PLTSIPVSTTTVASSEINT 1945
Query: 123 ASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQE-------IAAVPSAGR 175
S A P T + +P + PA + STP + + ++
Sbjct: 1946 LSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTL 2005
Query: 176 ERQPKEEGQKSSFSFS-SGIDQSPGMSPVPLREPMK--APLCGEGDQPGGFESQEKEAAG 232
P + ++ S S + G + + P + PL G S E
Sbjct: 2006 STTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLS 2065
Query: 233 GFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQ 292
P Q S + + A A T SA E SPL + IP P AS
Sbjct: 2066 TTPVDSKTQVTNSTEASSSATAEGSSMT-ISAPSEGSPL--LTSIPLSTTPVASPEASTL 2122
Query: 293 GEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAAS--QESCQQPVGAYLPHAELPWGL 350
P SNS EV+++ E Y +
Sbjct: 2123 STTPVD----------------SNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSM 2166
Query: 351 PSPALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEG-GLPVSPEPSL 409
P V + + +D P T N ++ EG +P S
Sbjct: 2167 PVSTTVVASSAISTLSTTPVDTST-PVT-------NSTEARSSPTTSEGTSMPTS----- 2213
Query: 410 LTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLE 469
TP+E + P +S+ P + +P+ E + S V + PV+ G
Sbjct: 2214 -TPSEGSTPFTSM---PVSTMPVVTSEASTLSATPVDTS-TPVTTSTEATSSPTTAEGTS 2268
Query: 470 RQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPG 529
S L S+G P +P ++T + V P + +
Sbjct: 2269 IPTSTL-SEGTTPLTS---IPVSHTLVANSEVSTLSTTPVDSNTP-------FTTSTEAS 2317
Query: 530 APPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEG--SRSPGDSPGGK---EEAPE 584
+PPP ++ G T ++ +T A + S +P D+ +A
Sbjct: 2318 SPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGS 2377
Query: 585 PPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHT 644
P D ++ + +S P + P +E+ S+HS P T
Sbjct: 2378 SPTTADDTSMP---TSTYSEGSTPLTSVPVSTMPVVSSEA----STHSTTPV------DT 2424
Query: 645 DGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPKCPDTLQSR 704
P + + EA +S P +G PT P G P + +
Sbjct: 2425 STPVTTSTEASSS-------------PTTAEGTSIPTSPPS-----EGTTPLASMPVSTT 2466
Query: 705 EGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPRG 764
+ L+ + P T E + E + S +G LLTS
Sbjct: 2467 PVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTAS-EGSTLLTSIPVSTT 2525
Query: 765 PACDASRQEFHAGVPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEW--P 822
P P D + + S G SE P
Sbjct: 2526 PVAS----------PEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTP 2575
Query: 823 LLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSPSHPGFKDQGADSSQIHVPVEPQ 882
L S +P + +++ + + P ETS S KD S I P E
Sbjct: 2576 LRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDT---SMPISTPSEVS 2632
Query: 883 EDNNLPTHGGQEQALGSELQSQLP-----KGTLSDTPTSSPTDMVWESSLTEESELSAPT 937
+L S L S +P TLS TP + T + T S+PT
Sbjct: 2633 T------------SLTSILVSTMPVASSEASTLSTTPVDTRTLVT-----TSTGTSSSPT 2675
Query: 938 RQKLPALGEKRPEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQAL 997
A G P G+ S P ++L +L N T +
Sbjct: 2676 T----AEGSSMPTSTPGER-----STPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTS 2726
Query: 998 ADALEEGSQHEEACQRHPGASEAADGCSPLWGL--SKREMASGNTGEAPPCQPD-SVALL 1054
A+A + E R S +DG +PL + S +AS D S+ +
Sbjct: 2727 AEASSSPTTAEGTSMR---ISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVT 2783
Query: 1055 DAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQQKMECWATSDAESPKLL 1114
+ + A PT ET + PV + + D +P
Sbjct: 2784 TSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTT 2843
Query: 1115 ASFPSAGEQGGEA-----GAAETGGSAGAGDPGKQQAPEKPGEATLSCGLLQTEHCLTSG 1169
++ S+ E A G + P +TLS + T +T+
Sbjct: 2844 STKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTS 2903
Query: 1170 EEASTSALRESCQAEHPMASCQDALLPARELGGIPRSTMDFSTHQAVPDPKELLLSGPPE 1229
E S+S P+++ + P L I ST+ + +A L + P +
Sbjct: 2904 TEGSSSPTTAE-GTSMPISTPSEVSTP---LTSILVSTVPVAGSEA-----STLSTTPVD 2954
Query: 1230 VAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPCPVGEPPLALENAASLKLFAG 1289
P T S+ AE + + + + R P S V P+A A++L
Sbjct: 2955 TRTPVTTSAEASSSPTT-AEGTSMPISTPGERRTPLTS-MSVSTMPVASSEASTLSRTPA 3012
Query: 1290 SLAPLLQPGAAGGEIPAVQASSGSPKARTTEG--PVDSMPCLDRMPLLAKGKQATGEEKA 1347
+ + P +G P + +EG P+ S+P
Sbjct: 3013 DTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIP-------------------V 3053
Query: 1348 ATAPGAGAKASGEGMAG-DAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTGFP 1406
+T P A +AS D+ S E P+ P +GTS + T SE LTG P
Sbjct: 3054 STTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPT--PAEGTSMPISTYSEGSTPLTGVP 3111
Score = 41.2 bits (95), Expect = 0.015
Identities = 275/1378 (19%), Positives = 436/1378 (31%), Gaps = 205/1378 (14%)
Query: 14 LSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSASLDPCLV 73
+ TP + +S + P S ++ + S+ + AS +++L V
Sbjct: 2481 VDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPV 2540
Query: 74 ---SPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASP-AAAP 129
SP VT A EG+ +P+ S E P SMP + P AS + P
Sbjct: 2541 DSNSPVVTSTEIS-SSATSAEGTSMPTSTYS-EGSTPLRSMPVSTKPLASSEASTLSTTP 2598
Query: 130 EDG--PQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSS 187
D P T S +P D + STP + ++ S P + S+
Sbjct: 2599 VDTSIPVTTSTETSSSPTTAKDTSMPI------STPSEVSTSLTSILVSTMPVASSEAST 2652
Query: 188 FSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQ 247
S +PV R + G S A G P S G S
Sbjct: 2653 LS----------TTPVDTRTLVTTST--------GTSSSPTTAEGSSMPT-STPGERSTP 2693
Query: 248 VTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEA----PPQYLTDD 303
+T + ++ L +P+ P+ A +S +G + P +
Sbjct: 2694 LTNILVSTTLLANSEASTLSTTPVDTSTPVTTS-AEASSSPTTAEGTSMRISTPSDGSTP 2752
Query: 304 LEFLRACHLPRSNSGAAPEAEVNA-------ASQESCQQPVGAYLPHAELPWGLPSPALV 356
L + LP ++S A+ + S E+ P A + +P PS
Sbjct: 2753 LTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEV--TSMPTSTPSETST 2810
Query: 357 P--------------EAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLP 402
P EAG +DT + + V EG
Sbjct: 2811 PLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTL 2870
Query: 403 VSPEPSLLTPTEEAHPASSLASFPA-AQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVV 461
++ P TP + AS+L++ P IP+ GSSS + MP+S + EV
Sbjct: 2871 LTSIPVSTTPVASSE-ASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPS--EVS 2927
Query: 462 DAGLVGLERQVSDLGSKGEHPEGDPGE--VPAPSPQERGEHLNTEQSHEVQPGVPPPPLP 519
L V GS+ P + P + E T + + P
Sbjct: 2928 TPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRT 2987
Query: 520 KEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGK 579
S V +P A SE++ P D ST + E S SP + G
Sbjct: 2988 PLTSMSVS------TMPVASSEASTLSRTPAD------TSTPVTTSTEASSSPTTAEGTG 3035
Query: 580 EEAPEPPDGGDP--------GNLQGEDSQAFSS----KRDPEVGKDELSKPSSDAESRDH 627
P +G P + ++ S+ P V E+S + AE
Sbjct: 3036 IPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSM 3095
Query: 628 P-SSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGA 686
P S++S G + P + +A + S P + PV + PT
Sbjct: 3096 PISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTP--VDTSTPVTTST-EAHSSPTTS--- 3149
Query: 687 IWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRK 746
EG+ + P + + + L + SE S TPV P E+T
Sbjct: 3150 --EGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEAT----S 3203
Query: 747 MGSCDGEGLLTS-PDQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTAL-------IL 798
+ +G + TS P + P V + P + A+ L T +
Sbjct: 3204 STTAEGTSIPTSTPSEGMTPLTSVP-------VSNTPVASSEASILSTTPVDSNTPLTTS 3256
Query: 799 DQDQQGIPSCPGEGWIRGAASEWPL-LSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKE 857
+ P+ G SE L+S + A ETS P
Sbjct: 3257 TEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYS 3316
Query: 858 TSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTLSDTP--T 915
+ S P D + +P + + P + + TLS TP T
Sbjct: 3317 QASSSPPIADGTS------MPTSTYSEGSTPL---TNMSFSTTPVVSSEASTLSTTPVDT 3367
Query: 916 SSPTDMVWESSLTEESELSAPTRQKLPALGEKRPEGACGDGQSSRVSPPAADVLKDFSLA 975
S+P E+SL +PT A G P + +G + S P + S
Sbjct: 3368 STPVTTSTEASL-------SPT----TAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEV 3416
Query: 976 GNFSRKETCCTGQGPNKSQQALADALEEGSQHEEACQRHPGASEAADGCSPL--WGLSKR 1033
S P S + + E S A S ++G +PL LS
Sbjct: 3417 NTLSTT--------PVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTT 3468
Query: 1034 EMASGNTGEAPPCQPD-SVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQP 1092
+AS D S + + P + A PT A E P
Sbjct: 3469 PVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTP 3528
Query: 1093 VPAPQQKMECWATSDAESPKLLASFPSAGEQGGEAGAAETGGSAGAGDPGKQQAPEKPGE 1152
V + + A++ + +P +F ++ Q + A + P + G
Sbjct: 3529 VASSE------ASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSE-------GS 3575
Query: 1153 ATLSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDALLPARELGGIPRSTMDFST 1212
++L+ LL + + +S EAST P D P + ST ST
Sbjct: 3576 SSLTTMLLSSTYVTSS--EAST-----------PSTPSVDRSTP------VTTSTQSNST 3616
Query: 1213 HQAVPDPKELL---LSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPC 1269
P P E++ +S P EV+ P T + S ++G + D P +
Sbjct: 3617 ----PTPPEVITLPMSTPSEVSTPLT--IMPVSTTSVTISEAGTASTLPVDTSTPVITST 3670
Query: 1270 PVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSMP 1327
V P+ E G+ P+ P + G P + + ++EG S P
Sbjct: 3671 QVSSSPVTPE---------GTTMPIWTP--SEGSTPLTTMPVSTTRVTSSEGSTLSTP 3717
Score = 35.4 bits (80), Expect = 0.84
Identities = 89/459 (19%), Positives = 148/459 (32%), Gaps = 45/459 (9%)
Query: 18 TPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSASLD--PCLVSP 75
TP + +S + P S ++ + SV + S +++L P S
Sbjct: 1071 TPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSI 1130
Query: 76 EVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQT 135
VT + EG+ +P+ PPS E P +SMP + A+ + +T
Sbjct: 1131 PVTTSTEASSSPTTAEGTSIPTSPPS-EGTTPLASMPVSTTLVVSSEANTLSTTPVDSKT 1189
Query: 136 QSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGID 195
Q A + P A +STP + + S P + S+ S +S +D
Sbjct: 1190 QVATSTEASSPP---PTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLS-TSPVD 1245
Query: 196 QSPGMSPVPL-REPMKAPLCGEGDQ-PGGFESQEKEAAGGFP-----------------P 236
S +PV E +P EG P S+ P P
Sbjct: 1246 TS---TPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTP 1302
Query: 237 AESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAP 296
+++ V + +P A +GT P+ IP + AS P
Sbjct: 1303 VDTKGPVVTSNEVSSSPTPA-EGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTP 1361
Query: 297 PQYLTDDLEFLRACHLPRSNSGAA-PEAEVNAASQESCQQPVGAYLPHAELPWGLPSPAL 355
T AC P ++ G + P + + + PV +P +
Sbjct: 1362 VDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVST------------TPVV 1409
Query: 356 VPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEE 415
EA +DT + + + EG P+ P TP
Sbjct: 1410 SSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVAN 1469
Query: 416 AHPASSLASFPA-AQIPIAVEEPGSSSRESVSKAGMPVS 453
+ AS+L++ P + P+ SSS + +S
Sbjct: 1470 SE-ASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAIS 1507
Score = 32.7 bits (73), Expect = 5.4
Identities = 264/1453 (18%), Positives = 450/1453 (30%), Gaps = 230/1453 (15%)
Query: 9 DNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSASL 68
D++ ++ T S+ PP N P S ++ + S+ + AS +++L
Sbjct: 478 DSKTQVTTSTEASSSPPTAEVN------SMPTSTPSEGSTPLTSMSVSTMPVASSEASTL 531
Query: 69 D--PCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPA 126
P S VT + + PEG+ +P+ PS E P ++MP +
Sbjct: 532 STTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPS-EGSTPLTNMPVST----------- 579
Query: 127 AAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKS 186
+ + A S+TP V ++ + +
Sbjct: 580 ----------------------RLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGT 617
Query: 187 SFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASV 246
S S+ ++ ++ + + + A S E P + S
Sbjct: 618 SMPTSTYSERGTTITSMSVSTTLVA-------------SSEASTLSTTPVDSNTPVTTST 664
Query: 247 QVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTDDLEF 306
+ T + A +S E S P+ +P + AS P T
Sbjct: 665 EATSSSTTAEGTSMPTSTYTEGS--TPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTS 722
Query: 307 LRACHLPRSNSGAA-PEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKE 365
A P + GA+ P + + S PV L + L + L +
Sbjct: 723 TEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPL-----DTSTH 777
Query: 366 ALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPV------SPEPSLL--TPTEEAH 417
+ + P T + P + + G +PV SPE S L TP +
Sbjct: 778 ITTSTEASCSPTTTEGTSMP--ISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNS 835
Query: 418 PASSLASFPAAQIPI-AVEEPGSSSRES-VSKAGMPVSADAAKEVVDAGLVGLERQVSDL 475
P ++ ++ P P S+ E MPVS V + + L D
Sbjct: 836 PVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTL---VATSAISTLSTTPVDT 892
Query: 476 GSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPL 535
+ P + E + G + T PG PL P + P +
Sbjct: 893 ST----PVTNSTEARSSPTTSEGTSMPTS-----TPGEGSTPLTS------MPDSTTPVV 937
Query: 536 PKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQ 595
+ P + ++TS EG+ P +P E P +
Sbjct: 938 SSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTP---SEGTTPLTSTPVSHTL 994
Query: 596 GEDSQAFS------SKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHS 649
+S+A + P E S P AE P+S P +G T P S
Sbjct: 995 VANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTS----TPSEGSTPLTRMPVS 1050
Query: 650 QT--AEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGS----GLQPKCPDTLQS 703
T A ++ S L + + + T +G S G P + +
Sbjct: 1051 TTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVST 1110
Query: 704 REGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPR 763
R L + SE S TPV P E++ + +G + TSP
Sbjct: 1111 R---------LVVSSEASTLSTTPVDTSIPVTTSTEAS---SSPTTAEGTSIPTSP---- 1154
Query: 764 GPACDASRQEFHAGVPHPPQGENLAADLGL-TALILDQDQQGIPSCPGEGWIRGAAS--- 819
P +G A + + T L++ + + + P + + A S
Sbjct: 1155 -----------------PSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEA 1197
Query: 820 EWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSPSHPGFKDQG---ADSSQIH 876
P ++E P+ E S P E S D S++
Sbjct: 1198 SSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETS 1257
Query: 877 VPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTL------SDTPTSSPTDMVWESSLTEE 930
E +LPT E GS L + +P T + T ++P D +T
Sbjct: 1258 SSPTTAEGTSLPTSTTSE---GSTLLTSIPVSTTLVTSPEASTLLTTPVD-TKGPVVTSN 1313
Query: 931 SELSAPTRQKLPALGEKRPEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKETCCTGQGP 990
S+PT PA G P +G++ S P L S S +
Sbjct: 1314 EVSSSPT----PAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVT 1369
Query: 991 NKSQQALADALEEGSQHEEACQRHPGASEAADGCSPLWGLSKREMASGNTGEAPPCQPDS 1050
++ + EG+ S ++G +PL + P
Sbjct: 1370 TSTEACSSPTTSEGTSMPN--------SNPSEGTTPLTSIPV---------STTPVVSSE 1412
Query: 1051 VALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQQ-KMECWATSDAE 1109
+ L A P + ++PG T + E + T EG P P + K + +
Sbjct: 1413 ASTLSATP----VDTSTPGTT----SAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSN 1464
Query: 1110 SPKLLASFPSAGEQGGEAGAAETGGSAGAGDP----GKQQAPEKPGEATLSCGLLQTEHC 1165
+P + + ++ + +A + P G A P E + + +
Sbjct: 1465 TPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTT 1524
Query: 1166 LTSGEE----ASTSALRESCQAEHPMASCQDALLPAREL-------GGIPRSTMDFSTHQ 1214
+ E ++T A+ + + AS + G P +++ ST
Sbjct: 1525 TVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTML 1584
Query: 1215 AVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPCPVGEP 1274
V L + P + T ++++ AE S + +S+ +P + PV
Sbjct: 1585 VVSSEANTLSTTPIDSKTQVT--ASTEASSSTTAEGSSM-TISTPSEGSPLLTSIPVSTT 1641
Query: 1275 PLALENAASLKLF-AGSLAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMP 1333
P+A A++L S +P++ P + P + TEG R P
Sbjct: 1642 PVASPEASTLSTTPVDSNSPVITSTEVSSS-PTPAEGTSMPTSTYTEG---------RTP 1691
Query: 1334 LLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGGVD 1393
L T T + A ++ D + S E P+ +GTS
Sbjct: 1692 L-------TSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPT--TSEGTSMPNS 1742
Query: 1394 TSSEQIATLTGFP 1406
T SE LT P
Sbjct: 1743 TPSEGTTPLTSIP 1755
Score = 32.0 bits (71), Expect = 9.3
Identities = 121/647 (18%), Positives = 194/647 (29%), Gaps = 79/647 (12%)
Query: 1 MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCT 60
+ + +++ + + P + +S + P S ++ + S+ +
Sbjct: 2763 VASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPV 2822
Query: 61 ASESSASLD--PCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPP 118
AS + +L P S VT K EG ++P S E +S+P + P
Sbjct: 2823 ASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTAS-EGSTLLTSIPVSTTPV 2881
Query: 119 EGCLASP-AAAPEDG--PQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEI--AAVPSA 173
AS + P D P T S +P + + STP I + VP A
Sbjct: 2882 ASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVA 2941
Query: 174 GRERQPKEEGQ-------KSSFSFSSGIDQSPGMS-PVPLREPMKAPLCGEGDQPGGFES 225
G E +S SS + G S P+ + PL S
Sbjct: 2942 GSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVAS 3001
Query: 226 QEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRA 285
E P S S + + A G S E S P+ IP P A
Sbjct: 3002 SEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGST--PLTSIPVSTTPVA 3059
Query: 286 SDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQ--ESCQQPVGAYLPH 343
P SNS EV+++ E P+ Y
Sbjct: 3060 IPEASTLSTTPVD----------------SNSPVVTSTEVSSSPTPAEGTSMPISTYSEG 3103
Query: 344 AELPWGLP---SPALVPEAGGSGKEALDT-------IDVQGHPQTGMRGTKPNQVVCVAA 393
+ G+P +P +DT + P T + P +
Sbjct: 3104 STPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTP--SE 3161
Query: 394 GGQPEGGLPVSP------EPSLL--------TPTEEAHPASSLASFPAAQIPIAVEEPGS 439
G P +PVS E S L TP + A+S + IP + G
Sbjct: 3162 GSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGM 3221
Query: 440 SSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGE 499
+ SV + PV++ A + + + + P + +P +P E
Sbjct: 3222 TPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGST 3281
Query: 500 HLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAP----SESARGPP---GPTDG 552
L + P S E + P P S+++ PP G +
Sbjct: 3282 PLTS----------MPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMP 3331
Query: 553 AKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDS 599
+ + ++P S +P S + P D P E S
Sbjct: 3332 TSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEAS 3378
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 90.5 bits (223), Expect = 2e-17
Identities = 247/1175 (21%), Positives = 392/1175 (33%), Gaps = 197/1175 (16%)
Query: 1247 GAEDSGVKAVSSADPRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPA 1306
G DS + SS+ E V + + ++ + A AP PG G P
Sbjct: 194 GQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPA--PGKVGDVTPQ 251
Query: 1307 VQASSGSPKART------TEGPVDSMPCLDRMPLLAKGKQATGEE----KAATAPGAGAK 1356
V+ + P R +E + + P + + E+ +AA+AP G
Sbjct: 252 VKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTP 311
Query: 1357 ASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGGVDTSSE--------QIATLTGFPDF 1408
G A S + G+P +D + + D+ E Q
Sbjct: 312 GKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQV 371
Query: 1409 REHIAKIFEKPVLGALATPGEKAG--AGRSAVGK-------------------DLTRPLG 1447
A E P GA P K G ++ GK +P G
Sbjct: 372 GAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSG 431
Query: 1448 --PEKLLDGPPGVDVT---LLPAPP-------ARLQVEKKQQLA------GEAEISHLAL 1489
P+ P + PAPP A++QV K+++ + +++ LA
Sbjct: 432 KAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAA 491
Query: 1490 QDPASDKLLGPAGLTWERNLPGAG-VGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQ 1548
+ A K LG + + G G +GK VPP P W E + S
Sbjct: 492 MNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKW---EEDSESS 548
Query: 1549 LERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSGKQHQETSACDS 1608
E S +P+ A + Q P S + Q P Q + D+
Sbjct: 549 SEESSDSSDGEVPTAVAPAQ-EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDN 607
Query: 1609 PHGEDGPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAGI 1668
+ D A + P + A + + L +P+ + P +T + V G
Sbjct: 608 SESSEESSDSADS---EEAPAAMTA-AQAKPALKIPQTKACPKKTNTTASAKVAPVRVGT 663
Query: 1669 LEMRNALGNQSTPAPPTGEVADTPLEPGKVAGAAGEAEGD-----ITLSTAETQACASGD 1723
R A G ++PA + VA P + + ++ E++ + + ++ + ++ G
Sbjct: 664 QAPRKA-GTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL 722
Query: 1724 LPEAGTTRTFSVVAGDL------VLPGSCQDPACSDKAPGMEGTAALHGDSPA------- 1770
+A + V G L VLPG KA E + + +S +
Sbjct: 723 QVKAASV----PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 778
Query: 1771 -------RPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESP 1823
+ QAK P R P+ G + S P T + + +P ++ +P
Sbjct: 779 AQVKTSVKKTQAKANPAAAR-APSAKGTI---SAPGKVVTAAAQAKQRSPSKVKPPVRNP 834
Query: 1824 R------PGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADLESP 1877
+ GP+ +PSV K A + +E G+ ES ++ E+
Sbjct: 835 QNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESD------------SEEEAE 882
Query: 1878 TLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEASTPSCP 1937
TLA G Q+ L SP A PP + PS
Sbjct: 883 TLAQVKPSGK-THQIRAALAPAKESPRKGAAPTPPG-----------------KTGPSAA 924
Query: 1938 DPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV 1997
K S SEE+ E+ P A PP + +P S P P
Sbjct: 925 QAGKQDDSGSSSEESDSDGEA--PAAVTSAQVIKPPLIFVDPNRS----PAGPAATPAQA 978
Query: 1998 PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDK-PIASSGTYNLDFDNIELVDTFQTLEPRA 2056
PR S R S S DED P T + + + + + P+A
Sbjct: 979 QAASTPRKARASESTARSSS---SESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKA 1035
Query: 2057 --------------SDAKNQEG-KVNTRRKSTDSVPISKSTLSRSLSLQASDFD-----G 2096
SD K QEG +K+ S+P++++ L + L+ +AS+
Sbjct: 1036 SMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAAL-KVLAQKASEAQPPVART 1094
Query: 2097 ASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQE 2156
SSG AV P +T S S K T K R P L + Q K P E
Sbjct: 1095 QPSSGVDSAVGTLP---ATSPQSTSVQAKGTNKLRKPKLPEVQQATK----APESSDDSE 1147
Query: 2157 PDEESLVPSGENLASETKTESAKTEGPSPA----LLEETPLEPA----VGPKAACPLDSE 2208
+S S E+ +SA T GP+P+ L+EET E + V P + L
Sbjct: 1148 DSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSL-LSGY 1206
Query: 2209 SAEGVVPPASGGGRVQ---NSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRL 2265
G+ P S + +S P TL P+ G QE P + +
Sbjct: 1207 MTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPD---------GKQEAKPQQAAGMLS 1257
Query: 2266 EFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLR 2300
++ +S Q++ P K G + + L+
Sbjct: 1258 PKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQ 1292
Score = 81.3 bits (199), Expect = 1e-14
Identities = 296/1419 (20%), Positives = 459/1419 (32%), Gaps = 284/1419 (20%)
Query: 8 SDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSAS 67
S N L A P S + ++ K T S H + L G + S
Sbjct: 107 STNSSVLGADLPSSMKEKAKAET--EKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPS 164
Query: 68 LDPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLA-SPA 126
+ LVS E GA G + S + SSS E EG + PA
Sbjct: 165 ANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSS---DETDVEGKPSVKPA 221
Query: 127 AAPEDGPQT-QSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQK 185
T +SP R+ AP APG + TP + A+P A R ++P+EE +
Sbjct: 222 QVKASSVSTKESPARKAAP-APGKVGDV--------TPQVKGGALPPAKRAKKPEEESES 272
Query: 186 SSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVAS 245
S G ES+E+ AG ++ + +
Sbjct: 273 SE---------------------------------EGSESEEEAPAGTRSQVKASEKILQ 299
Query: 246 VQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTDDLE 305
V+ A +A +GT P K A Q A + + E+ + +D E
Sbjct: 300 VR----AASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEE----DSESSSEESSDSEE 351
Query: 306 FLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKE 365
A + ++V AAS + + P P P G PA+ G +E
Sbjct: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP---APPGKTGPAVAKAQAGKREE 408
Query: 366 ALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLP---VSPEPSLLTPTEEAHPASSL 422
+ + + A +P G P + P+ +P + A PA
Sbjct: 409 DSQSSSEESDSEEE-----------APAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPR 457
Query: 423 ASFP-AAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEH 481
+ P AAQ+ + +E SR S ++ A AA +G QV + G
Sbjct: 458 KTGPAAAQVQVGKQE--EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG 515
Query: 482 PEG------DPGEVPAPSPQ------ERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPG 529
P G PG+V +P E ++E+S + G P + Q +
Sbjct: 516 PLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNI 575
Query: 530 APPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGG 589
P S A+GPP V + P E S DS EEAP
Sbjct: 576 LQAKP----TSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDS-ADSEEAPAAMTA- 629
Query: 590 DPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHS 649
+QA + + P+ K K ++ A ++ P Q PRK G T S
Sbjct: 630 ---------AQAKPALKIPQT-KACPKKTNTTASAKVAPVRVGTQAPRKAGTA-TSPAGS 678
Query: 650 QTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGR 709
A A + P + + G A G GLQ K ++ + LG+
Sbjct: 679 SPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAA-SVPVKGSLGQ 737
Query: 710 MESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPRGPACDA 769
T PT A K ++ ES+ E D E SP Q +
Sbjct: 738 G----TAPVLPGKTGPTVTQVKAEKQEDSESSEE-----ESDSEEAAASPAQVK------ 782
Query: 770 SRQEFHAGVPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKH 829
V N AA +A +G S PG+ + AA++ S K
Sbjct: 783 ------TSVKKTQAKANPAAARAPSA-------KGTISAPGK--VVTAAAQAKQRSPSK- 826
Query: 830 LQPSQAQPETSIFDVLKEQAQPPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPT 889
++P P+ S + + A P GK A ++ P+ED+
Sbjct: 827 VKPPVRNPQNSTV-LARGPASVPSVGK-------------AVATAAQAQTGPEEDS---- 868
Query: 890 HGGQEQALGSELQSQLPKGTLSDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRP 949
G E+ SE +++ TL+ S T + R L E
Sbjct: 869 -GSSEEESDSEEEAE----TLAQVKPSGKTHQI---------------RAALAPAKESPR 908
Query: 950 EGACGDGQSSRVSPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQHEE 1009
+GA +PP GP+ +Q D S+ +
Sbjct: 909 KGAA-------PTPPGK---------------------TGPSAAQAGKQDDSGSSSEESD 940
Query: 1010 ACQRHPGASEAADGCSPLWGLSKREMASGNTGEAPPCQPDSVALLDAVPCLPALAPASPG 1069
+ P A +A P N A P PA A A+
Sbjct: 941 SDGEAPAAVTSAQVIKP-----PLIFVDPNRSPAGPA------------ATPAQAQAAST 983
Query: 1070 VTPTQDAPETEACDETQEGRQQPVPAPQQKMECWATSDAESPKLLASFPSAGEQGGEAGA 1129
+ + T ++ + +PA Q T+ P + P + AGA
Sbjct: 984 PRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMP---TAHPRIAPKASMAGA 1040
Query: 1130 AETGGSAGAGDPGKQQAPEKPGEATLSCGLLQTEHCLTSGEEASTSALRESCQAEHPMAS 1189
+ + S+ D KQ+ P L T+ L +++ +A+ P+A
Sbjct: 1041 SSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAAL-------KVLAQKASEAQPPVAR 1093
Query: 1190 CQDALLPARELGGIPRSTMDFSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAE 1249
Q + +G +P ++ ++ QA G ++ P P + + A ++
Sbjct: 1094 TQPSSGVDSAVGTLPATSPQSTSVQA---------KGTNKLRKPKLPEVQQATKAPESSD 1144
Query: 1250 DSGVKAVSSADPRAPGE-----------SPCPVGEPPLALENAA----------SLKLFA 1288
DS + SS+ GE P P L E AA S L +
Sbjct: 1145 DSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLS 1204
Query: 1289 GSLAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATGEEKAA 1348
G + P L P + QAS +PK +DS P + LA G+++A
Sbjct: 1205 GYMTPGLTPANS-------QASKATPK-------LDSSPSVS--STLAAKDDPDGKQEAK 1248
Query: 1349 TAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQG 1387
AG + G A+G T + S+ PK+G
Sbjct: 1249 PQQAAGMLSPKTGGKEAASGTTP-------QKSRKPKKG 1280
Score = 76.6 bits (187), Expect = 3e-13
Identities = 289/1345 (21%), Positives = 434/1345 (32%), Gaps = 175/1345 (13%)
Query: 251 EAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQ-GEAPPQYLTDD-LEFLR 308
EA A + T A S L P +A + G+ G + P T + L
Sbjct: 93 EAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLL 152
Query: 309 ACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALD 368
+ PR + A P A S+ + V A+ A+ G+ S + + D
Sbjct: 153 SGKSPRKS--AEPSANTTLVSETEEEGSVPAFGAAAKP--GMVSAGQADSSSEDTSSSSD 208
Query: 369 TIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLL---TPTEE--AHPASSLA 423
DV+G P KP QV + + +P P + TP + A P + A
Sbjct: 209 ETDVEGKPSV-----KPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRA 263
Query: 424 SFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPE 483
P + + E GS S E + AG A+++++ + + P
Sbjct: 264 KKPEEESESS--EEGSESEEE-APAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPP 320
Query: 484 GDPGEVP----APSPQERGEHLNTEQS--HEVQPGVPPPPLPKEQSHEVQPGAPPPPLPK 537
G G V A P+E E + E S E P K Q GA P +
Sbjct: 321 GKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKE 380
Query: 538 APSESAR-GPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQG 596
+P + A PPG T PAVAK + GK E
Sbjct: 381 SPRKGAAPAPPG----------KTGPAVAK--------AQAGKRE--------------- 407
Query: 597 EDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADA 656
EDSQ+ S + D E +KPS A S+ + + PRKG A P +T A A
Sbjct: 408 EDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA---PAPPRKTGPAAA 464
Query: 657 SGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWE---GSGLQPKCPDTLQSREGLGRMESF 713
K E+ D E A G Q K T+ G+G +
Sbjct: 465 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM----GMGPLGKG 520
Query: 714 LTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGE-GLLTSPDQPRGPACDASRQ 772
P TP A+V ++ ES+ E S DGE +P Q + +
Sbjct: 521 AGPVPPGKVGPATPSAQVGKWEEDSESSSE-ESSDSSDGEVPTAVAPAQEKSLGNILQAK 579
Query: 773 EFHAGVPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQP 832
+ PPQ A +D + S + E P + +P
Sbjct: 580 PTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDS-----ADSEEAPAAMTAAQAKP 634
Query: 833 SQAQPET-------------SIFDVLKEQAQPPENGKETSP--SHP----GFKDQGADSS 873
+ P+T + V P + G TSP S P G + DSS
Sbjct: 635 ALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS 694
Query: 874 QIHVPVEPQEDNNLPTHGGQEQALGSELQ---------SQLPKGTLSDTP-TSSPTDMVW 923
+E L GQ +++G LQ L +GT P + PT
Sbjct: 695 SSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV 754
Query: 924 ESSLTEESELSAPTRQKLPALGEKRPEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKET 983
++ E+SE S A ++ +P AA + S G S
Sbjct: 755 KAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA---RAPSAKGTIS---- 807
Query: 984 CCTGQGPNKSQQALADALEEGSQHEEACQRHPGASEAADGCSPLWGLSKREMASGNTGEA 1043
P K A A A + + R+P S +A G
Sbjct: 808 -----APGKVVTAAAQAKQRSPSKVKPPVRNPQNSTV--------------LARG----- 843
Query: 1044 PPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQQKMECW 1103
P SV + A A P E+++ +E + Q ++
Sbjct: 844 ----PASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAA 899
Query: 1104 ATSDAESPKLLASFPSAGEQGGEAGAAETGGSAGAGDPGKQQAPEKPGEATLSCGLLQTE 1163
ESP+ A+ G+ G A A +G+ E P T S +++
Sbjct: 900 LAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVT-SAQVIKPP 958
Query: 1164 HCLTSGEEASTSALRESCQAEHPMASCQDALLP--ARELGGIPRSTMDFSTHQAVPDPKE 1221
+ QA Q A P AR RS+ S + V +
Sbjct: 959 LIFVDPNRSPAGPAATPAQA-------QAASTPRKARASESTARSSSSESEDEDVIPATQ 1011
Query: 1222 LLLSG--PPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPCPVGEPPLALE 1279
L G V P A+ GA S + S + G + + P +L
Sbjct: 1012 CLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLP 1071
Query: 1280 -NAASLKLFAGSLAPLLQPGA----------AGGEIPAVQASSGSPKARTTEGPVDSMPC 1328
A+LK+ A + P A A G +PA S S +A+ T P
Sbjct: 1072 LTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKL--RKPK 1129
Query: 1329 LDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQGT 1388
L + K +++ + + ++ +G++ GEG G + T G E +
Sbjct: 1130 LPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAE 1189
Query: 1389 SGGVDTSSEQIATLTGF--PDFREHIAKIFE-KPVLGALATPGEKAGAGRSAVGKDLTRP 1445
S D + + L+G+ P ++ + P L + + A GK +P
Sbjct: 1190 SSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKP 1249
Query: 1446 LGPEKLLDGPPGVDVTLLPAPPARLQVEKKQQLAGEAEISHLALQDPASDKLLGPAGLTW 1505
+L G P + + KK AG + S LALQ + LLG W
Sbjct: 1250 QQAAGMLSPKTGGKEAASGTTPQKSRKPKKG--AGNPQASTLALQSNITQCLLGQ---PW 1304
Query: 1506 ERNLPGAGVGKEMAGVPPTLREDER 1530
N A V + V L E ER
Sbjct: 1305 PLN--EAQVQASVVKVLTELLEQER 1327
Score = 68.2 bits (165), Expect = 1e-10
Identities = 203/962 (21%), Positives = 326/962 (33%), Gaps = 195/962 (20%)
Query: 1529 ERPEGPGAAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEA 1588
E P A PG G Q++ A P E E + + + AP +
Sbjct: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV 291
Query: 1589 VAQDRIPSGKQHQETSACDSPHGEDGPGDF-AHTGVPGHVPRSTCAPSPQREVLTVPEAN 1647
A ++I Q +A G G G A G G V T A P+ + + E +
Sbjct: 292 KASEKIL-----QVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES 346
Query: 1648 SEPWTLDTLGGERRPGVTAGILEMR-----NALGNQSTPAPPTGEVADTPLEPGKVAGAA 1702
S+ E +L+ + + +G S PA + P PGK A
Sbjct: 347 SD--------SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAV 398
Query: 1703 GEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTA 1762
+A+ +++ + S EA P + S KAP + +
Sbjct: 399 AKAQAGKREEDSQSSSEESDSEEEA---------------PAQAKP---SGKAPQVRAAS 440
Query: 1763 ALHGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRES 1822
A +SP + P P R +V V E + + EE +DRE+
Sbjct: 441 APAKESPRKGAA----PAPPRKTGPAAAQVQVGKQEEDSRS--------SSEESDSDREA 488
Query: 1823 PRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPA--------DL 1874
+ P +P+V K S G G + PV + PA P+ D
Sbjct: 489 -LAAMNAAQVKPLGKSPQV--KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDS 545
Query: 1875 ESPTLAAS-SYHGDVVGQV------STDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGD 1927
ES + +S S G+V V S I Q+ P ++ A PP A P
Sbjct: 546 ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQA-KPTSSPAKGPPQKA-------GPVAV 597
Query: 1928 RVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPP 1987
+V+A P D ++ SSDS ++ E P + T +A PA P + P+ +T
Sbjct: 598 QVKAEKPM--DNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTT---- 651
Query: 1988 EEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVD 2047
++ PV G ++ G+ P S P + GT
Sbjct: 652 ----ASAKVAPVRVGTQAPRKAGTATSPAGSS---------PAVAGGT------------ 686
Query: 2048 TFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEAV 2106
+ A D+ + E + K+ +V + ++ ++ + L ++A+ S G A
Sbjct: 687 -----QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP 741
Query: 2107 ALAPDAYSTGSSSASST-LKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPS 2165
L G + + T +K K+ S +++ +++ +P +T + + P+
Sbjct: 742 VL------PGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 795
Query: 2166 GENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQN 2225
S T SA P AA S V PP QN
Sbjct: 796 AARAPSAKGTISA----------------PGKVVTAAAQAKQRSPSKVKPPVR---NPQN 836
Query: 2226 SPPVGRKTLPLTTAPEA-GEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPP 2284
S + R + + +A + +G +EDS + SE++S + + E
Sbjct: 837 STVLARGPASVPSVGKAVATAAQAQTGPEEDSGS-----------SEEESDSEEEAETLA 885
Query: 2285 PTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDD 2344
K GK + L K PR A P P G K DD
Sbjct: 886 QVKPSGKTHQIRAALAPAK-------------ESPRKGAAPTP-PGKTGPSAAQAGKQDD 931
Query: 2345 PNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASA 2404
+ S S E+P + P VDP +++P+ P+ +PA
Sbjct: 932 SGSSSEESDSD-GEAPAAVTSAQVIKPPLI--FVDP----NRSPAGPAATPAQ------- 977
Query: 2405 MEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISA 2464
A+ TP K R +S RS S+ +D PA TP + +
Sbjct: 978 --------------AQAASTPRKA---RASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
Query: 2465 VV 2466
VV
Sbjct: 1021 VV 1022
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 90.5 bits (223), Expect = 2e-17
Identities = 247/1147 (21%), Positives = 384/1147 (33%), Gaps = 196/1147 (17%)
Query: 1265 GESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVD 1324
G+SP EP A S GS+ P A G + A QA S S D
Sbjct: 154 GKSPRKSAEPS-ANTTLVSETEEEGSV-PAFGAAAKPGMVSAGQADSSSE---------D 202
Query: 1325 SMPCLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDP 1384
+ D + K + + +AA+AP G G A S + G+P +D
Sbjct: 203 TSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDS 262
Query: 1385 KQGTSGGVDTSSE--------QIATLTGFPDFREHIAKIFEKPVLGALATPGEKAG--AG 1434
+ + D+ E Q A E P GA P K G
Sbjct: 263 ESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVA 322
Query: 1435 RSAVGK-------------------DLTRPLG--PEKLLDGPPGVDVT---LLPAPP--- 1467
++ GK +P G P+ P + PAPP
Sbjct: 323 KAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKT 382
Query: 1468 ----ARLQVEKKQQLA------GEAEISHLALQDPASDKLLGPAGLTWERNLPGAG-VGK 1516
A++QV K+++ + +++ LA + A K LG + + G G +GK
Sbjct: 383 GPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGK 442
Query: 1517 EMAGVPPTLREDERPEGPGAAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAA 1576
VPP P W E + S E S +P+ A +
Sbjct: 443 GAGPVPPGKVGPATPSAQVGKW---EEDSESSSEESSDSSDGEVPTAVAPAQ-EKSLGNI 498
Query: 1577 FQVAPHSHGEEAVAQDRIPSGKQHQETSACDSPHGEDGPGDFAHTGVPGHVPRSTCAPSP 1636
Q P S + Q P Q + D+ + D A + P + A +
Sbjct: 499 LQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADS---EEAPAAMTA-AQ 554
Query: 1637 QREVLTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGEVADTPLEPG 1696
+ L +P+ + P +T + V G R A G ++PA + VA P
Sbjct: 555 AKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKA-GTATSPAGSSPAVAGGTQRPA 613
Query: 1697 KVAGAAGEAEGD-----ITLSTAETQACASGDLPEAGTTRTFSVVAGDL------VLPGS 1745
+ + ++ E++ + + ++ + ++ G +A + V G L VLPG
Sbjct: 614 EDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASV----PVKGSLGQGTAPVLPGK 669
Query: 1746 CQDPACSDKAPGMEGTAALHGDSPA--------------RPQQAKEQPGPERPIPAGDGK 1791
KA E + + +S + + QAK P R P+ G
Sbjct: 670 TGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAAR-APSAKGT 728
Query: 1792 VCVSSPPEPDETHDPKLQHLAPEELHTDRESPR------PGPSMLPSVPKKDAPRVMDKV 1845
+ S P T + + +P ++ +P+ GP+ +PSV K A +
Sbjct: 729 I---SAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQT 785
Query: 1846 TSDETRGAEGTESSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAA 1905
+E G+ ES ++ E+ TLA G Q+ L SP
Sbjct: 786 GPEEDSGSSEEESD------------SEEEAETLAQVKPSGK-THQIRAALAPAKESPRK 832
Query: 1906 AHAGLPPSAAEHIVSPSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAP 1965
A PP + PS K S SEE+ E+ P
Sbjct: 833 GAAPTPPG-----------------KTGPSAAQAGKQDDSGSSSEESDSDGEA--PAAVT 873
Query: 1966 PAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFD 2025
A PP + +P S P P PR S R S S D
Sbjct: 874 SAQVIKPPLIFVDPNRS----PAGPAATPAQAQAASTPRKARASESTARSSS---SESED 926
Query: 2026 EDK-PIASSGTYNLDFDNIELVDTFQTLEPRA--------------SDAKNQEG-KVNTR 2069
ED P T + + + + + P+A SD K QEG
Sbjct: 927 EDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVS 986
Query: 2070 RKSTDSVPISKSTLSRSLSLQASDFD-----GASSSGNPEAVALAPDAYSTGSSSASSTL 2124
+K+ S+P++++ L + L+ +AS+ SSG AV P +T S S
Sbjct: 987 KKNPASLPLTQAAL-KVLAQKASEAQPPVARTQPSSGVDSAVGTLP---ATSPQSTSVQA 1042
Query: 2125 KRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPS 2184
K T K R P L + Q K P E +S S E+ +SA T GP+
Sbjct: 1043 KGTNKLRKPKLPEVQQATK----APESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPT 1098
Query: 2185 PA----LLEETPLEPA----VGPKAACPLDSESAEGVVPPASGGGRVQ---NSPPVGRKT 2233
P+ L+EET E + V P + L G+ P S + +S P T
Sbjct: 1099 PSRTETLVEETAAESSEDDVVAPSQSL-LSGYMTPGLTPANSQASKATPKLDSSPSVSST 1157
Query: 2234 LPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKP 2293
L P+ G QE P + + ++ +S Q++ P K G
Sbjct: 1158 LAAKDDPD---------GKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQ 1208
Query: 2294 VAKMPLR 2300
+ + L+
Sbjct: 1209 ASTLALQ 1215
Score = 78.2 bits (191), Expect = 1e-13
Identities = 274/1276 (21%), Positives = 420/1276 (32%), Gaps = 169/1276 (13%)
Query: 316 NSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGH 375
++ + E E A ++ + P A + L LPS ++ +A ++A T + H
Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPS-SMKEKAKAETEKAGKTGNSMPH 141
Query: 376 PQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIP--IA 433
P TG V + +G P S +L++ TEE S+ +F AA P ++
Sbjct: 142 PATG------KTVANLLSGKSPRKSAEPSANTTLVSETEEE---GSVPAFGAAAKPGMVS 192
Query: 434 VEEPGSSSRESVSKAG-MPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVP-- 490
+ SSS ++ S + V A+++++ + + P G G V
Sbjct: 193 AGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 252
Query: 491 --APSPQERGEHLNTEQS--HEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESAR-G 545
A P+E E + E S E P K Q GA P ++P + A
Sbjct: 253 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 312
Query: 546 PPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSK 605
PPG T PAVAK + GK E EDSQ+ S +
Sbjct: 313 PPG----------KTGPAVAK--------AQAGKRE---------------EDSQSSSEE 339
Query: 606 RDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGE 665
D E +KPS A S+ + + PRKG A P +T A A K E
Sbjct: 340 SDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA---PAPPRKTGPAAAQVQVGKQEE 396
Query: 666 EDPVLPPVPDGAGEPTVPEGAIWE---GSGLQPKCPDTLQSREGLGRMESFLTLESEKSD 722
+ D E A G Q K T+ G+G +
Sbjct: 397 DSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM----GMGPLGKGAGPVPPGKV 452
Query: 723 FPPTPVAEVAPKAQEGESTLEIRKMGSCDGE-GLLTSPDQPRGPACDASRQEFHAGVPHP 781
P TP A+V ++ ES+ E S DGE +P Q + + + P
Sbjct: 453 GPATPSAQVGKWEEDSESSSE-ESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP 511
Query: 782 PQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPET-- 839
PQ A +D + S + E P + +P+ P+T
Sbjct: 512 PQKAGPVAVQVKAEKPMDNSESSEESSDS-----ADSEEAPAAMTAAQAKPALKIPQTKA 566
Query: 840 -----------SIFDVLKEQAQPPENGKETSP--SHP----GFKDQGADSSQIHVPVEPQ 882
+ V P + G TSP S P G + DSS +
Sbjct: 567 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEE 626
Query: 883 EDNNLPTHGGQEQALGSELQ---------SQLPKGTLSDTP-TSSPTDMVWESSLTEESE 932
E L GQ +++G LQ L +GT P + PT ++ E+SE
Sbjct: 627 EKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSE 686
Query: 933 LSAPTRQKLPALGEKRPEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKETCCTGQGPNK 992
S A ++ +P AA + S G S P K
Sbjct: 687 SSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA---RAPSAKGTIS---------APGK 734
Query: 993 SQQALADALEEGSQHEEACQRHPGASEAADGCSPLWGLSKREMASGNTGEAPPCQPDSVA 1052
A A A + + R+P S +A G P SV
Sbjct: 735 VVTAAAQAKQRSPSKVKPPVRNPQNSTV--------------LARG---------PASVP 771
Query: 1053 LLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQQKMECWATSDAESPK 1112
+ A A P E+++ +E + Q ++ ESP+
Sbjct: 772 SVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPR 831
Query: 1113 LLASFPSAGEQGGEAGAAETGGSAGAGDPGKQQAPEKPGEATLSCGLLQTEHCLTSGEEA 1172
A+ G+ G A A +G+ E P T S +++ +
Sbjct: 832 KGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVT-SAQVIKPPLIFVDPNRS 890
Query: 1173 STSALRESCQAEHPMASCQDALLP--ARELGGIPRSTMDFSTHQAVPDPKELLLSG--PP 1228
QA Q A P AR RS+ S + V + L G
Sbjct: 891 PAGPAATPAQA-------QAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 943
Query: 1229 EVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPCPVGEPPLALE-NAASLKLF 1287
V P A+ GA S + S + G + + P +L A+LK+
Sbjct: 944 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1003
Query: 1288 AGSLAPLLQPGA----------AGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAK 1337
A + P A A G +PA S S +A+ T P L + K
Sbjct: 1004 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKL--RKPKLPEVQQATK 1061
Query: 1338 GKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGGVDTSSE 1397
+++ + + ++ +G++ GEG G + T G E + S D +
Sbjct: 1062 APESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAP 1121
Query: 1398 QIATLTGF--PDFREHIAKIFE-KPVLGALATPGEKAGAGRSAVGKDLTRPLGPEKLLDG 1454
+ L+G+ P ++ + P L + + A GK +P +L
Sbjct: 1122 SQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSP 1181
Query: 1455 PPGVDVTLLPAPPARLQVEKKQQLAGEAEISHLALQDPASDKLLGPAGLTWERNLPGAGV 1514
G P + + KK AG + S LALQ + LLG W N A V
Sbjct: 1182 KTGGKEAASGTTPQKSRKPKKG--AGNPQASTLALQSNITQCLLGQ---PWPLN--EAQV 1234
Query: 1515 GKEMAGVPPTLREDER 1530
+ V L E ER
Sbjct: 1235 QASVVKVLTELLEQER 1250
Score = 75.5 bits (184), Expect = 7e-13
Identities = 269/1287 (20%), Positives = 417/1287 (32%), Gaps = 252/1287 (19%)
Query: 14 LSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASE-SSASLDPCL 72
LS ++PR + P + + + ++ P A+ G V G ++SE +S+S D
Sbjct: 152 LSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD 211
Query: 73 V----SPEVTEPRKDPQGARGPEGS-LLPSPP--------------PSQEREHPS--SSM 111
V S ++ + R A+G G P+PP P ++ E S SS
Sbjct: 212 VEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSD 271
Query: 112 PFAECPPEGCLASPAAAPE-------DGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPY 164
E P L A+ + P +SPR+ AP PG A
Sbjct: 272 SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPA----------- 320
Query: 165 QEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFE 224
A AG+ +EE +SS S +++P + + KAP P E
Sbjct: 321 ---VAKAQAGK----REEDSQSSSEESDSEEEAPAQA----KPSGKAPQVRAASAPAK-E 368
Query: 225 SQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESS------AVLEKSPLKPMAPIP 278
S K AA PP ++ A VQV + + ES A + + +KP+ P
Sbjct: 369 SPRKGAAPA-PPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSP 427
Query: 279 Q-DPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEV-------NAASQ 330
Q PA G+G P P A P A+V ++S+
Sbjct: 428 QVKPASTMGMGPLGKGAGPVP--------------PGKVGPATPSAQVGKWEEDSESSSE 473
Query: 331 ESCQQPVG----AYLPHAELPWG---LPSPALVPEAGGSGKEALDTIDVQGHPQTGMRGT 383
ES G A P E G P P G K + VQ + M +
Sbjct: 474 ESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAG--PVAVQVKAEKPMDNS 531
Query: 384 KPNQVVCVAAGGQ--PEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAV------- 434
+ ++ +A + P +P+L P +A P + + A P+ V
Sbjct: 532 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRK 591
Query: 435 ---------------------EEPGSSSRESVS---KAGMPVSADAAKEVVDAGLVGLER 470
E SSS ES S K G+ V+ AK V GL+
Sbjct: 592 AGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK----GLQV 647
Query: 471 QVSDLGSKGEHPEGD----PGEVPAPSPQERGEHL----NTEQSHEVQPGVPPPPLPKEQ 522
+ + + KG +G PG+ Q + E ++E+ + + P K
Sbjct: 648 KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 707
Query: 523 SHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEA 582
+ Q A P ++ PG A SP+ K R+P +S
Sbjct: 708 VKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGP 767
Query: 583 PEPPDGGDPGNLQG-------EDSQAFSSKRDPEVGKDELS--KPSSD--------AESR 625
P G EDS + + D E + L+ KPS A ++
Sbjct: 768 ASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAK 827
Query: 626 DHPSSHSA-QPPRKGG-----AGHTDGPHSQTAEADASG-LPHKLGEEDPVLPPV--PDG 676
+ P +A PP K G AG D S + E+D+ G P + + PP+ D
Sbjct: 828 ESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDP 887
Query: 677 AGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDF------------- 723
P P A P ++ E R S ESE D
Sbjct: 888 NRSPAGP--AATPAQAQAASTPRKARASESTARSSS---SESEDEDVIPATQCLTPGIRT 942
Query: 724 ----PPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFHAGVP 779
PT +APKA ++ DG+ + GPA S++
Sbjct: 943 NVVTMPTAHPRIAPKASMAGASSSKESSRISDGK-------KQEGPATQVSKK------- 988
Query: 780 HPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPET 839
+P A L + A + Q + + A P S P +
Sbjct: 989 NPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATS------PQSTSVQA 1042
Query: 840 SIFDVLKEQAQPPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGS 899
+ L++ P +P + +DSS +ED P LG
Sbjct: 1043 KGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSS-----GSEEDGEGPQGAKSAHTLG- 1096
Query: 900 ELQSQLPKGTLSDTPTSSPTDMVWESSLTEESE--LSAPTRQKLPALGEKRPEGACGDGQ 957
PT S T+ + E + E SE + AP++ L G P + Q
Sbjct: 1097 --------------PTPSRTETLVEETAAESSEDDVVAPSQSLLS--GYMTPGLTPANSQ 1140
Query: 958 SSRVSPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQHEEACQRHPGA 1017
+S+ +P L + S T P+ Q+A + Q G
Sbjct: 1141 ASKATP---------KLDSSPSVSSTLAAKDDPDGKQEA------KPQQAAGMLSPKTGG 1185
Query: 1018 SEAADGCSPLWGLSKREMASGNTGEAPPCQPDSVALLDAVPCLPALAPASPGV----TPT 1073
EAA G +P ++ A Q + L P A V T
Sbjct: 1186 KEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTEL 1245
Query: 1074 QDAPETEACDETQEGRQQPVPAPQQKMECWATSDAESPKLLASFPSAGEQGGEAG----- 1128
+ + D T+E ++ + ++K+ A +P+ +GGEA
Sbjct: 1246 LEQERKKVVDTTKESSRKGWESRKRKLS-GDQPAARTPRSKKKKKLGAGEGGEASVSPEK 1304
Query: 1129 AAETGGSAGAGDPGKQQAPEKPGEATL 1155
+ T D EK G+ +L
Sbjct: 1305 TSTTSKGKAKRDKASGDVKEKKGKGSL 1331
Score = 59.7 bits (143), Expect = 4e-08
Identities = 243/1219 (19%), Positives = 403/1219 (33%), Gaps = 212/1219 (17%)
Query: 1550 ERSRQELASGLPSPAATQ------ELPVERAAAFQVAPHSHGEEAVAQDRIPSGKQHQET 1603
E + E A P A+T +LP + G+ + +GK
Sbjct: 92 EEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANL 151
Query: 1604 SACDSPHGEDGPGD----FAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGE 1659
+ SP P + T G VP A P +++SE + + +
Sbjct: 152 LSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD 211
Query: 1660 RRPGVTAGILEMRNALGNQSTPAPPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQAC 1719
+ IL++R A S PA T TP PGK A + + +E+ +
Sbjct: 212 VEVKASEKILQVRAA----SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE 267
Query: 1720 ASGDLPE---AGTTRTFSVVAGDLVLPGSCQDPA-------CSDKAPGMEGTAALHGDSP 1769
S D E A + +G G+ PA + PG G A +
Sbjct: 268 ESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAG 327
Query: 1770 ARPQQAK----------EQPGPERP-----------IPAGDGKVCVSSPPEPDETHDPKL 1808
R + ++ E P +P PA + ++P P +T
Sbjct: 328 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAA 387
Query: 1809 QHLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAE-------GTESSPV 1861
Q ++ R S S ++ +A +V S + + A G + PV
Sbjct: 388 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPV 447
Query: 1862 ADDIIQPAAPA--------DLESPTLAAS-SYHGDVVGQV------STDLIAQSISPAAA 1906
+ PA P+ D ES + +S S G+V V S I Q+ P ++
Sbjct: 448 PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQA-KPTSS 506
Query: 1907 HAGLPPSAAEHIVSPSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPP 1966
A PP A P +V+A P D ++ SSDS ++ E P + T +A P
Sbjct: 507 PAKGPPQKA-------GPVAVQVKAEKPM--DNSESSEESSDSADSEEAPAAMTAAQAKP 557
Query: 1967 APPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDE 2026
A P + P+ +T ++ PV G ++ G+ P S +
Sbjct: 558 ALKIPQTKACPKKTNTT--------ASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGT 609
Query: 2027 DKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNT------------------ 2068
+P S + E T+ S K + K +
Sbjct: 610 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGK 669
Query: 2069 RRKSTDSVPISKSTLSRSLSLQASDFDGASSS--------------GNPEAVALAPDAYS 2114
+ V K S S S + SD + A++S NP A A AP A
Sbjct: 670 TGPTVTQVKAEKQEDSES-SEEESDSEEAAASPAQVKTSVKKTQAKANP-AAARAPSAKG 727
Query: 2115 TGSS-------SASSTLKRTKKPRPPSLKKKQTT---KKPTETPPV-------KETQQEP 2157
T S+ +A + + K +PP + +T + P P V + Q P
Sbjct: 728 TISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP 787
Query: 2158 DEESLVPSGENLASETKTESAKTEGPSP---------ALLEETPLEPAV-------GPKA 2201
+E+S S E SE + E+ PS A +E+P + A GP A
Sbjct: 788 EEDS-GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSA 846
Query: 2202 A---------CPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGG 2252
A + ++G P A +V P + P P+ +
Sbjct: 847 AQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI-------FVDPNRSPAGPAATPA 899
Query: 2253 QEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIG---KKPVAKMPLRRPKMKKTPE 2309
Q + + R + SS ++ P T+ + + V MP P++
Sbjct: 900 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAP--- 956
Query: 2310 KLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNF 2369
K AS + + +D +G T K NP S L Q++
Sbjct: 957 KASMAGASSSKESSRISDGKKQEGPATQVSKK------NPASLPLTQAALKVLAQKASEA 1010
Query: 2370 DPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTD 2429
P ++T S A +PA++ ++ V G NK K K ++
Sbjct: 1011 QPPV-----------ARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQA 1059
Query: 2430 TFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVD-- 2487
T K+P+ S S+ S + + P + H L T + + +
Sbjct: 1060 T----KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHT-----LGPTPSRTETLVEETA 1110
Query: 2488 LEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDD------- 2540
E+ + D PS T +P + + +++ + S+L DD
Sbjct: 1111 AESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEA 1170
Query: 2541 APKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVN--TAAKNQHPVPRG 2598
P++ A L T + + + S P +G+ T AL + T P P
Sbjct: 1171 KPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLN 1230
Query: 2599 LAPNQESHLQVPEKSSQKE 2617
A Q S ++V + ++E
Sbjct: 1231 EAQVQASVVKVLTELLEQE 1249
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 90.1 bits (222), Expect = 3e-17
Identities = 213/886 (24%), Positives = 286/886 (32%), Gaps = 169/886 (19%)
Query: 39 PGSPDHR----------DASSIGSVGLGGFCTASESSASLDPCLVSPEVTEP-RKDPQGA 87
PG HR DA G G G + + + P + E P P GA
Sbjct: 262 PGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGA 321
Query: 88 RGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQ-------TQSPRR 140
RG +G+ + PP P P G + A E GPQ Q R
Sbjct: 322 RGNDGATGAAGPPG----------PTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRG 371
Query: 141 EPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGM 200
EP P PG AA PA + G + QP +G + GI +PG
Sbjct: 372 EPGP--PGPAGAAGPAG--------------NPGADGQPGAKGANGA----PGIAGAPGF 411
Query: 201 SPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGT 260
PG + GG P + G P A
Sbjct: 412 -------------------PGARGPSGPQGPGGPPGPKGNSG---------EPGAPGSKG 443
Query: 261 ESSAVLEKSPLKPMAPIPQDPAPRASDRERG-QGEAPPQYLTDDLEFLRACHLPRSNSGA 319
++ A E P+ P P P + +RG +GE P L P G
Sbjct: 444 DTGAKGEPGPVGVQGP----PGPAGEEGKRGARGEPGPTGLPGP---------PGERGGP 490
Query: 320 APEAEVNAASQESCQQPVGAY-LPHAELPWGLPSPALVP-EAGGSGKEALDTIDVQGHPQ 377
A + P G P P G P A P EAG G + L
Sbjct: 491 GSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGL---------- 540
Query: 378 TGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEP 437
TG G+ G + G P P P A + + FP + A EP
Sbjct: 541 TGSPGSPGPDGKTGPPGPAGQDGRPGPPGPP------GARGQAGVMGFPGPKG--AAGEP 592
Query: 438 GSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEH-PEGDPG----EVPAP 492
G + V G P + A + +AG G G +GE P G PG PA
Sbjct: 593 GKAGERGVP--GPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAG 650
Query: 493 SPQERGEHLNTEQSHEVQPGVPPPPLPK-EQSHEVQPGAPPPPLPKAPSESARGPPGPTD 551
P E G+ EQ G P P + E+ + G PP P P A G PG D
Sbjct: 651 PPGEAGKP--GEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGP-RGANGAPG-ND 706
Query: 552 GAKVHEDSTSP-AVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSK----- 605
GAK D+ +P A +G+ PG + A P GD G+ + + K
Sbjct: 707 GAK--GDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRG 764
Query: 606 ------------RDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAE 653
+ G+ S P+ +R P +P G AG GP +
Sbjct: 765 LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRG-EPGPPGPAGFA-GPPGADGQ 822
Query: 654 ADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIW----EGSGLQPKCPDTLQSREGLGR 709
A G P G + PP P G P P G + +G+ P GR
Sbjct: 823 PGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGR 882
Query: 710 MESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPRGPACDA 769
+ + PP P + K GE+ R GE P P GPA +
Sbjct: 883 VGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRP-----GE---VGPPGPPGPAGEK 934
Query: 770 SRQ--EFHAGVPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSE 827
+ AG P P + +A G+ L + ++G P PG G + P +S
Sbjct: 935 GSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPG--KQGPSGASG 992
Query: 828 KHLQPSQAQPETSIFDVLKEQAQPPENGKETSPSHPGFKDQGADSS 873
+ P P P E+G+E +P G G D S
Sbjct: 993 ERGPPGPMGPPGL-------AGPPGESGREGAPGAEG--SPGRDGS 1029
Score = 77.0 bits (188), Expect = 3e-13
Identities = 255/1105 (23%), Positives = 351/1105 (31%), Gaps = 172/1105 (15%)
Query: 71 CLVSPEVTEPRKD--------PQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPP---- 118
C V P+ +E D P+G GP G P+ PP ++ +P PP
Sbjct: 92 CPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPG 151
Query: 119 --------------------EGCLASPAAAPEDGPQ-TQSPRREPAPNA-------PGDI 150
G ++ P GP+ P P P PG+
Sbjct: 152 PPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEP 211
Query: 151 AAAFP-AERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPM 209
A+ P R P + AG+ +P E G + G+ + G+ +
Sbjct: 212 GASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGP-QGARGLPGTAGLPGMKGHRGF 270
Query: 210 KAPLCGEGDQ-PGGFESQE-KEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLE 267
+GD P G + + G P +G+ + P AP A A
Sbjct: 271 SGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGA 330
Query: 268 KSPLKPMAPIPQDPAPRASDRERGQGEAPPQ--YLTDDLEFLRACHLPRSNSGAA-PEAE 324
P P P P A +GEA PQ ++ + +R P +GAA P
Sbjct: 331 AGPPGPTGPAGPPGFPGAVG---AKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGN 387
Query: 325 VNAASQESCQQPVGA-------YLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHP- 376
A Q + GA P A P G P P G+ E G P
Sbjct: 388 PGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGE-------PGAPG 440
Query: 377 ---QTGMRGTKPNQVVCVA----AGGQPEGGLPVSPEPSLL--TPTEEAHPASSLASFPA 427
TG +G +P V AG + + G P P+ L P E P S FP
Sbjct: 441 SKGDTGAKG-EPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGS--RGFPG 497
Query: 428 AQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPG 487
A +A + + R S AG S A +AGL G + GS G P+G G
Sbjct: 498 AD-GVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG--PDGKTG 554
Query: 488 EVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPK----EQSHEVQPGAPPPPLPKAPS--- 540
P P+ Q+ Q GV P PK E + G P PP P+
Sbjct: 555 P-PGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKD 613
Query: 541 --ESARGPPGPTDGA-KVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGE 597
A+GPPGP A + E + + +G P PG EA +P + G PG+L
Sbjct: 614 GEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPG---EAGKPGEQGVPGDLGAP 670
Query: 598 DSQAFSSKR--DPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTA--- 652
+R E G P+ + P + A KG AG P SQ A
Sbjct: 671 GPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGA----KGDAGAPGAPGSQGAPGL 726
Query: 653 -----EADASGLPHKLGEEDPVLPPVPDGAG------------EPTVPEGAIWEGSGLQP 695
E A+GLP G+ P DG+ P P GA + P
Sbjct: 727 QGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGP 786
Query: 696 KCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGL 755
P G PP P P +G+ + + G +G
Sbjct: 787 SGPAGPTGARG--------APGDRGEPGPPGPAGFAGPPGADGQPGAK-GEPGDAGAKG- 836
Query: 756 LTSPDQPRGPA--------CDASRQEFHAGVPHPPQGENLAADLGLTALILDQDQQGIPS 807
P P GPA A + G PP G G P
Sbjct: 837 DAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPG 896
Query: 808 CPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSPSHPGFKD 867
PG G + P + +P + P E+ P +G +P PG +
Sbjct: 897 PPGPAGKEG--GKGPRGETGPAGRPGEVGPPGPP-GPAGEKGSPGADGPAGAPGTPGPQG 953
Query: 868 QGADSSQIHVPVEPQEDN--NLPTHGGQ--EQALGSELQSQLPKGTLSDTPTSSPTDMVW 923
+ +P + E LP G+ +Q + P G + + P
Sbjct: 954 IAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPG--- 1010
Query: 924 ESSLTEESELSAPTRQKLPALGEKRPEGACGD-GQSSRVSPPAA----DVLKDFSLAG-N 977
E AP + P G GA GD G++ PP A AG +
Sbjct: 1011 -----ESGREGAPGAEGSP--GRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKS 1063
Query: 978 FSRKETCCTG----------QGPNKSQQALADALEEGSQHEEACQRHPGASEAADGCSPL 1027
R ET G +GP Q D E G Q + + H G S P
Sbjct: 1064 GDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPP 1123
Query: 1028 WGLSKREMASGNTGEAPPCQPDSVA 1052
G + SG +G A P P A
Sbjct: 1124 -GSPGEQGPSGASGPAGPRGPPGSA 1147
Score = 69.7 bits (169), Expect = 4e-11
Identities = 316/1393 (22%), Positives = 417/1393 (29%), Gaps = 301/1393 (21%)
Query: 107 PSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQE 166
P + +P EC P S + ++ + P+ + P P A P RD
Sbjct: 82 PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAG--PPGRDGIPGQPG 139
Query: 167 IAAVPSAGRERQPKEEGQKSSFSFSSGIDQSP--GMS-PVPLREPMKAPLCGEGDQPG-- 221
+ P P G + S G D+ G+S P P+ L G PG
Sbjct: 140 LPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQ 199
Query: 222 GFESQEKEAAGGFPPAESRQGVASVQVTPEAPAA--AQQGTESSAVLEKSPLKPMAPIPQ 279
GF+ PP E + AS + P P + G + A P +P P
Sbjct: 200 GFQG---------PPGEPGEPGASGPMGPRGPPGPPGKNGDDGEA---GKPGRPGERGP- 246
Query: 280 DPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSG-AAPEAEVNAASQESCQQPVG 338
P P+ + G P L + ++G A P+ E + + +G
Sbjct: 247 -PGPQGARGLPGTAGLPGMKGHRGFSGLDGA---KGDAGPAGPKGEPGSPGENGAPGQMG 302
Query: 339 AYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPE 398
P GLP P A G G RG A G P
Sbjct: 303 --------PRGLPGERGRPGAPGPA---------------GARGNDG----ATGAAGPPG 335
Query: 399 GGLPVSPE--PSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADA 456
P P P + EA P Q P E P E G P A A
Sbjct: 336 PTGPAGPPGFPGAVGAKGEAGP----------QGPRGSEGPQGVRGEP----GPPGPAGA 381
Query: 457 AKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPS-PQERGEHLNTEQSHEVQPGVPP 515
A + G G G+KG + G PG AP P RG S PG PP
Sbjct: 382 AGPAGNPGADGQP------GAKGAN--GAPGIAGAPGFPGARGP------SGPQGPGGPP 427
Query: 516 PPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDS 575
P + + +PGAP A+G PGP V +G P
Sbjct: 428 GP----KGNSGEPGAPG----SKGDTGAKGEPGP--------------VGVQGPPGPAGE 465
Query: 576 PGGKEEAPEP-PDG--GDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHS 632
G + EP P G G PG G S+ F G D ++ P A R P
Sbjct: 466 EGKRGARGEPGPTGLPGPPGERGGPGSRGFP-------GADGVAGPKGPAGERGSPGP-- 516
Query: 633 AQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVP---DGAGEPTVPEGAIWE 689
A P G G +G P G + PP P DG P P GA +
Sbjct: 517 AGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQ 576
Query: 690 GSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGS 749
+ P G P P V P ++GE+ +
Sbjct: 577 AGVMGFPGPKGAAGEPGKAGERGV-----------PGPPGAVGPAGKDGEAGAQ------ 619
Query: 750 CDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTALILDQDQQGIPS-- 807
P P GPA + Q G P + L G +QG+P
Sbjct: 620 --------GPPGPAGPAGERGEQ----GPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDL 667
Query: 808 -CPGEGWIRGAASEWPLLSSEKHLQ--PSQAQPETSIFDVLKEQAQPPENGKETSPSHPG 864
PG RG E+ +Q P A P + P +G + PG
Sbjct: 668 GAPGPSGARGERG----FPGERGVQGPPGPAGPRGA-------NGAPGNDGAKGDAGAPG 716
Query: 865 FK-DQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTLSDTPTSSPTDMVW 923
QGA Q +P G G PKG D + P
Sbjct: 717 APGSQGAPGLQ-----------GMPGERGAAGLPG-------PKGDRGD---AGPKGADG 755
Query: 924 ESSLTEESELSAPTRQKLPALGEKRPEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKET 983
L+ P +G P GA GD S S PA
Sbjct: 756 SPGKDGVRGLTGP-------IGPPGPAGAPGDKGESGPSGPA------------------ 790
Query: 984 CCTGQGPNKSQQALADALEEGSQHEEACQRHPGASEAADGCSPLWGLSKREMASGNTGEA 1043
GP ++ A D E G PGA + G G + + +G G A
Sbjct: 791 -----GPTGARGAPGDRGEPGPPGPAGFAGPPGA-DGQPGAKGEPGDAGAKGDAGPPGPA 844
Query: 1044 PPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQQKMECW 1103
P P P AP + G + P GR P P P
Sbjct: 845 GPAGPPG-------PIGNVGAPGAKGARGSAGPPGATGFPGAA-GRVGP-PGP------- 888
Query: 1104 ATSDAESPKLLASFPSAGEQGGEAGAAETGGSAGAGDPGKQQAPEKPGEATLSCGLLQTE 1163
+ +A P AG++GG+ ETG AG PG+ P PG A
Sbjct: 889 -SGNAGPP---GPPGPAGKEGGKGPRGETGP---AGRPGEVGPPGPPGPA---------- 931
Query: 1164 HCLTSGEEASTSALRESCQAEHPMASCQDALLPARELGGIP--RSTMDFSTHQAVPDPKE 1221
GE+ S A A P + R + G+P R F +P P
Sbjct: 932 -----GEKGSPGA---DGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGF---PGLPGP-- 978
Query: 1222 LLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPCPVGEPPLALENA 1281
SG P P ++ +RG + P G P E + +
Sbjct: 979 ---SGEPGKQGPS------GASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGS 1029
Query: 1282 ASLKLFAGSLAPLLQPGAAGGE-IPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQ 1340
K G P PGA G P +G R GP P P+ A+G
Sbjct: 1030 PGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAG--PAGPVGPVGARG-- 1085
Query: 1341 ATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIA 1400
G + G + G+ G G G P +QG SG + +
Sbjct: 1086 PAGPQGPRGDKGETGEQGDRGIKGHRG--FSGLQGPPGPPGSPGEQGPSGASGPAGPR-- 1141
Query: 1401 TLTGFPDFREHIAKIFEKPVLGALATPGEKAGAGRSA-VGKDLTRPLGPEKLLDGPP--- 1456
G P K + G + PG + G + VG P GP GPP
Sbjct: 1142 ---GPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGP--PGPPGP----PGPPGPP 1192
Query: 1457 --GVDVTLLPAPP 1467
G D + LP PP
Sbjct: 1193 SAGFDFSFLPQPP 1205
Score = 68.9 bits (167), Expect = 7e-11
Identities = 166/691 (24%), Positives = 217/691 (31%), Gaps = 112/691 (16%)
Query: 32 KRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSASLDPCLVSPEVTEPRKDPQGARGPE 91
K ++ PG P ++G G G E+ A P P + P G+ G +
Sbjct: 594 KAGERGVPGPP-----GAVGPAGKDG-----EAGAQGPPGPAGPAGERGEQGPAGSPGFQ 643
Query: 92 GSLLPSPPPSQEREHPSSSMP--FAECPPEGCLASPAAAPEDGPQTQSPRREP--APNAP 147
G P+ PP + + +P P G E G Q P A AP
Sbjct: 644 GLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAP 703
Query: 148 GDIAAAFPAERDSSTPYQEIAAVPSAGRERQ----PKEEGQKSSFSFSSGIDQSPGMSPV 203
G+ A A + Q + ER P +G + G D SPG V
Sbjct: 704 GNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAG-PKGADGSPGKDGV 762
Query: 204 -----PLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGV---ASVQVTPEA--- 252
P+ P A G+ + G A G P G A P A
Sbjct: 763 RGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQ 822
Query: 253 PAAAQQGTESSAVLEKSPLKPMAPI-PQDPAPR--ASDRERGQGEAPPQYLTDDLEFLRA 309
P A + ++ A + P P P P P A + +G A P T
Sbjct: 823 PGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGR 882
Query: 310 CHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDT 369
P + A P A +E + P G P A P + P AG G D
Sbjct: 883 VGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGP-AGRPGEVGPPGPPGPAGEKGSPGAD- 940
Query: 370 IDVQGHPQT-GMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAA 428
G P T G +G + V G + E G P P PS + AS P
Sbjct: 941 -GPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGP 999
Query: 429 QIPIAVE-EPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPG 487
P + PG S RE G G E GS G +GD G
Sbjct: 1000 MGPPGLAGPPGESGRE--------------------GAPGAEGSPGRDGSPGA--KGDRG 1037
Query: 488 EVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPP--PLPKAPSESARG 545
E P PG P P GAP P P K+ G
Sbjct: 1038 ETGPAGP----------------PGAPGAP-----------GAPGPVGPAGKSGDRGETG 1070
Query: 546 PPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSK 605
P GP V G+R P G + + E + GD G ++G + FS
Sbjct: 1071 PAGPAG-----------PVGPVGARGPAGPQGPRGDKGETGEQGDRG-IKGH--RGFSGL 1116
Query: 606 RDPEVGKDELSKPSSDAESRDHPSSHSAQP---PRKGGAGHTDGPHSQTAEADASGLPHK 662
+ P P S E +S A P P GA DG + G +
Sbjct: 1117 QGPP------GPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGR 1170
Query: 663 LGEEDPVLPPVPDGAGEPTVPEGAIWEGSGL 693
G+ PV PP P G P P A ++ S L
Sbjct: 1171 TGDAGPVGPPGPPGPPGPPGPPSAGFDFSFL 1201
Score = 65.9 bits (159), Expect = 6e-10
Identities = 212/858 (24%), Positives = 272/858 (31%), Gaps = 143/858 (16%)
Query: 1225 SGPPEVA-APDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGES--------PCPVGEP- 1274
+G P +A AP P S Q G K +S +P APG P PVG
Sbjct: 400 NGAPGIAGAPGFPGARGPSGPQGPGGPPGPKG-NSGEPGAPGSKGDTGAKGEPGPVGVQG 458
Query: 1275 ---PLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDR 1331
P E + G PG GG S G P A GP P +R
Sbjct: 459 PPGPAGEEGKRGARGEPGPTGLPGPPGERGGP-----GSRGFPGADGVAGPKG--PAGER 511
Query: 1332 -MPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGE-TEGSMERMGEPSQDPKQGTS 1389
P A K + GE A PG +G+ G +G G QD + G
Sbjct: 512 GSPGPAGPKGSPGE---AGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPP 568
Query: 1390 GGVDTSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGEKAGAGRS--AVGKDLTRPLG 1447
G + A + GFP + + + G PG AG+ A + P G
Sbjct: 569 GPPGARGQ--AGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAG 626
Query: 1448 P-----EKLLDGPPGVDVTLLPA-PPARLQVEKKQQLAGEAEI-------------SHLA 1488
P E+ G PG PA PP +Q + G+
Sbjct: 627 PAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERG 686
Query: 1489 LQDPASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQ 1548
+Q P GPAG PG K AG P P GA PGL+G
Sbjct: 687 VQGPP-----GPAGPRGANGAPGNDGAKGDAGAPGA------PGSQGA--PGLQGMPG-- 731
Query: 1549 LERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSG-------KQHQ 1601
ER A+GLP P + + A +P G + P G K
Sbjct: 732 -ERG----AAGLPGPKGDRGDAGPKGA--DGSPGKDGVRGLTGPIGPPGPAGAPGDKGES 784
Query: 1602 ETSACDSPHGEDG-PGDFAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGER 1660
S P G G PGD G PG P P P + P A EP G
Sbjct: 785 GPSGPAGPTGARGAPGDRGEPGPPG--PAGFAGP-PGAD--GQPGAKGEPGDAGAKGDAG 839
Query: 1661 RPGVTAGILEMRNALGNQSTPAPPTGEVADTPLEPGKVAGAAGEA-----EGDITLSTAE 1715
PG AG +GN P + P GAAG G+
Sbjct: 840 PPG-PAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPP 898
Query: 1716 TQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAALHGDSPARPQQA 1775
A G G T G++ PG PA +PG +G A G +P PQ
Sbjct: 899 GPAGKEGGKGPRGETGPAGR-PGEVGPPGP-PGPAGEKGSPGADGPAGAPG-TPG-PQGI 954
Query: 1776 KEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRP-GPSMLPSVP 1834
Q G +P G+ P P + +P Q P +R P P GP L P
Sbjct: 955 AGQRGVVG-LPGQRGER--GFPGLPGPSGEPGKQ--GPSGASGERGPPGPMGPPGLAGPP 1009
Query: 1835 ----KKDAPRVMDKVTSDETRGAEGT--ESSPVADDIIQPAAPADLESPTLAASSYHGDV 1888
++ AP D + GA+G E+ P P AP +P
Sbjct: 1010 GESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGP----PGAPGAPGAP---------GP 1056
Query: 1889 VGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEASTPSCPDPAKDLSRSSD 1948
VG PA + P A P P GD+ E
Sbjct: 1057 VGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETG--------------EQ 1102
Query: 1949 SEEAFETPESTTPVKAPPAPPPPPPEVIPE----PEVSTQPP-----PEEPGCGSETVPV 1999
+ + + ++ PP PP P E P P PP P + G P+
Sbjct: 1103 GDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPI 1162
Query: 2000 -PDGPRSDSVEGSPFRPP 2016
P GPR + + P PP
Sbjct: 1163 GPPGPRGRTGDAGPVGPP 1180
Score = 63.9 bits (154), Expect = 2e-09
Identities = 259/1070 (24%), Positives = 327/1070 (30%), Gaps = 231/1070 (21%)
Query: 1072 PTQDAPETEACDETQEGRQQPVPAPQQKMECWATSDAESPKLLASFPSAGEQGGEAGAAE 1131
P + PE E C +G + P T+ E PK G +G A
Sbjct: 82 PGAEVPEGECCPVCPDGSESPTDQE--------TTGVEGPK-----GDTGPRGPRGPAGP 128
Query: 1132 TGGSAGAGDPGKQQAPEKPGE-ATLSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASC 1190
G G PG P PG G +E ST + PM
Sbjct: 129 PGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGI----SVPGPMGPS 184
Query: 1191 QDALLPARELGGIPRSTMDFSTHQAVP-DPKELLLSGPPEVAAPDTPYLHVDSAAQRGAE 1249
LP P Q P +P E SGP P P + +
Sbjct: 185 GPRGLPG------PPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGP-------PGKNGD 231
Query: 1250 DSGVKAVSSADPRAPGESPCPVGEPPLALENAASL---------------KLFAGSLAPL 1294
D + P PGE P + L A L K AG P
Sbjct: 232 DG-----EAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPK 286
Query: 1295 LQPGAAGGE-IPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATGEEKAATAPGA 1353
+PG+ G P G P R G P A+G G AA PG
Sbjct: 287 GEPGSPGENGAPGQMGPRGLPGERGRPGAPG--------PAGARGND--GATGAAGPPGP 336
Query: 1354 GAKASGEGMAG--DAAGE--------TEGSMERMGEPSQDPKQGTSG-----GVD----- 1393
A G G A GE +EG GEP G +G G D
Sbjct: 337 TGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGA 396
Query: 1394 ---TSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGEKAGAGRSAV--GKDLTRPLGP 1448
+ IA GFP R G PG K +G K T G
Sbjct: 397 KGANGAPGIAGAPGFPGARGPSGP------QGPGGPPGPKGNSGEPGAPGSKGDTGAKGE 450
Query: 1449 EKLLDGPPGVDVTLLPAPPARLQVEKKQQLAGEAEISHL-----------ALQDPASDKL 1497
GP GV PP E K+ GE + L + P +D +
Sbjct: 451 P----GPVGVQ-----GPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGV 501
Query: 1498 LGPAGLTWERNLPG----------------AGV--GKEMAGVPPTLREDERPEGPGAAW- 1538
GP G ER PG AG+ K + G P + D + PG A
Sbjct: 502 AGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQ 561
Query: 1539 ---------PGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEAV 1589
PG GQA + + A+G P A + +P A V P EA
Sbjct: 562 DGRPGPPGPPGARGQA-GVMGFPGPKGAAGEPGKAGERGVPGPPGA---VGPAGKDGEAG 617
Query: 1590 AQ----DRIPSGKQHQETSACDSP--HGEDGP-GDFAHTGVPGH--VPRSTCAPSPQREV 1640
AQ P+G++ ++ A SP G GP G G PG VP AP P
Sbjct: 618 AQGPPGPAGPAGERGEQGPA-GSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPS--- 673
Query: 1641 LTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGEVADTPLEPGKVAG 1700
A E G + PG AG A GN A P PG G
Sbjct: 674 ----GARGERGFPGERGVQGPPG-PAGPRGANGAPGNDGAKGD-----AGAPGAPGS-QG 722
Query: 1701 AAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLV--LPGSCQDPACSDKAPGM 1758
A G +G A GD +AG D V L G P + APG
Sbjct: 723 APG-LQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAG-APGD 780
Query: 1759 EGTAALHGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHT 1818
+G + G PA P A+ PG +R P G + PP D K + P +
Sbjct: 781 KGESGPSG--PAGPTGARGAPG-DRGEPGPPGPAGFAGPPGADGQPGAKGE---PGDAGA 834
Query: 1819 DRESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDI------IQPAAPA 1872
++ PGP+ P+ P P + V + +GA G+ P A + P P+
Sbjct: 835 KGDAGPPGPAG-PAGP----PGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPS 889
Query: 1873 DLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSA--PA----- 1925
P G G+ + P PP A SP A PA
Sbjct: 890 GNAGPP-GPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGT 948
Query: 1926 ----------------GDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPP 1969
G R E P P P+ E + P + + PP P
Sbjct: 949 PGPQGIAGQRGVVGLPGQRGERGFPGLPGPS--------GEPGKQGPSGASGERGPPGPM 1000
Query: 1970 PPPPEVIPEPEVSTQPPPEEPGCGSETVPVPD---GPRSDSVEGSPFRPP 2016
PP P E + P G+E P D G + D E P PP
Sbjct: 1001 GPPGLAGPPGESGREGAP-----GAEGSPGRDGSPGAKGDRGETGPAGPP 1045
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 90.1 bits (222), Expect = 3e-17
Identities = 199/862 (23%), Positives = 286/862 (33%), Gaps = 124/862 (14%)
Query: 1680 TPAPPTGEVADTPLEPG--KVAGAAG--------EAEGDITLSTAETQACASGDLPEAGT 1729
TP PP P+ P +V GAAG E G I +T A +G AGT
Sbjct: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGT 85
Query: 1730 T------------RTFSVVAGDLVLPGSCQDP--ACSDKAPGMEGTAALHGDSPARPQQA 1775
+ R PG P A PG G L + +
Sbjct: 86 SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 145
Query: 1776 KEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPSMLPSVPK 1835
K P+R + + S P T P + + T+ PRP PS P P
Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPG--TPSPAMARRS-RAAGTEVGLPRPAPSARPRPPT 202
Query: 1836 KDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADLESP-TLAASSYHGDVVGQVST 1894
+ + + + T TE SP A +P+A L+ P + + SS + +
Sbjct: 203 EGPRKSVSSASEHST-----TEPSPAARR--RPSAGGGLQRPASRSLSSSATPLSSPARS 255
Query: 1895 DLIAQSISPAAAHAGLPPSAAEHIVSP---------SAPAGDRVEASTPSCPDPAKDLSR 1945
A+ A AH P + P +APA + +S + P P+ +R
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315
Query: 1946 SSDSEEAFETPESTTPVKAPPAPP--------PPPPEVIPEPEVSTQPPPEEPGCGSETV 1997
+ TP P PP+PP PP P P + PP P ++
Sbjct: 316 PVPPPDNAATP---LPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSM 372
Query: 1998 PVPDGPRSDSVEGSPFRPPSHSFSA--VFDEDKPIASSG---TYNLDFDNIELVDTFQTL 2052
P S++ P HS ++ + P+A S T +L ++ +F T+
Sbjct: 373 TTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTM 432
Query: 2053 EPRASDAKNQEGKVNTRRKST--DSVPISKS-TLSRSLSLQASDFDGASSSGNPEAVALA 2109
PR + A +R ST DS P+ +L S LQ S S +P +
Sbjct: 433 SPRQTQASLTSP---SRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL 489
Query: 2110 PDAYSTGSSSASSTLKRTKKP--------RPPSLKKKQTTKKPTETPPVKETQQEPDEES 2161
S S S + L P PPSL QT TPP++ S
Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL---QTPPASLTTPPLENLP------S 540
Query: 2162 LVPSGENLASETKTESAKTEGPSPALLE-ETPLEPAVGPKAACPLDSESAEGVVPPASGG 2220
L P AS T P PA + P P P P + PPA
Sbjct: 541 LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS 600
Query: 2221 GRVQN--SPPVG-----------RKTLPLTTAPEAGEVTPSDSGGQEDSPA--KGLSVRL 2265
+Q SPP+ LP AP + +P S SP L+V L
Sbjct: 601 PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 660
Query: 2266 -EFDYSEDKSSWDNQQENPPPTKKIGKK--PVAKMP--LRRPKMKKTPEKLDNTPASPPR 2320
+ +S S +PP + + P ++ P L P ++ P + P SP
Sbjct: 661 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 720
Query: 2321 SPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDP 2380
+P P+A P +P S+T + P L P + P
Sbjct: 721 TPPPQAPPPLAAPPLQVPPSPPASPPMSP-SATPPPRVPPLLAAPPLQVPPSP--PASLP 777
Query: 2381 FKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRS 2440
+K P P PA P A+ + G + P+ S
Sbjct: 778 MSPLAKPP--PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM-------------S 822
Query: 2441 PLSDPPSQDPTPAATP--ETPP 2460
PL+ PP Q P A P + PP
Sbjct: 823 PLATPPPQAPPVLAAPLLQVPP 844
Score = 64.3 bits (155), Expect = 2e-09
Identities = 143/623 (22%), Positives = 199/623 (31%), Gaps = 132/623 (21%)
Query: 78 TEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQS 137
T P + P P LPSPP S P + P PP SP A+P S
Sbjct: 589 TPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP-----PLS 643
Query: 138 PRREPAPNAPGDIAAAF---PAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGI 194
P P+P AP +A P S P Q + P++ S S +
Sbjct: 644 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS----------PPVSPSATPPS 693
Query: 195 DQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVAS--VQVTPEA 252
P ++ PL+ P P + + PP ++ +A+ +QV P
Sbjct: 694 QAPPSLAAPPLQVPPSPP------------ASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741
Query: 253 PAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRA----SDRERGQGEAPPQYLTDDLEFLR 308
PA+ ++ PL P+ P+P A S + +APP T L+ L
Sbjct: 742 PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801
Query: 309 ACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALD 368
+ P S G AP + P A LP SP P A
Sbjct: 802 S--PPASFPGQAP------------------FSPSASLPM---SPLATPPPQAPPVLAAP 838
Query: 369 TIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAA 428
+ V P P + P +P P T + P +LA P
Sbjct: 839 LLQVPPSPPASPTLQAPRR--------------PPTPGPD----TSVSGPRLTLALAPGP 880
Query: 429 QIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGE 488
P SS+ AG SA + E +L PEG
Sbjct: 881 --PPPPSRSPSSTLSGPDLAGHSSSATSTPE--------------ELRGYDSGPEGGAAA 924
Query: 489 VPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPG 548
P P + H P PPL GAP PLP P+ PG
Sbjct: 925 SPPPDAELAACH------PAAWSRGPAPPLAFR-------GAPGAPLPWPPATG----PG 967
Query: 549 PTDG-AKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRD 607
DG ++E EG S +PG + P P G G + A +S R
Sbjct: 968 SADGLCTIYE--------TEGPESATPAPGALDPGPSP---GTSGGKAAAGAGAGASSRS 1016
Query: 608 PEVGK-DELSKPSSDAESRDH--------PSSHSAQPPRKGGAGHTDGPHSQTAEADASG 658
P+ + EL + A H ++ A GG G +G T A A+
Sbjct: 1017 PKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEG-GGVTGGARAAL 1075
Query: 659 LPHKLGEEDPVLPPVPDGAGEPT 681
+LG +L P+ + T
Sbjct: 1076 SDAELGRWAELLSPLDESRASIT 1098
Score = 63.9 bits (154), Expect = 2e-09
Identities = 216/1019 (21%), Positives = 319/1019 (31%), Gaps = 131/1019 (12%)
Query: 419 ASSLASFPAAQIP--IAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLG 476
A + A PAA+ P + PGS + PV+ A + + AG VG + G
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSP------RPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
Query: 477 SKGEH--PEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPP 534
G PE P P S + P PP + + P P
Sbjct: 64 GIGGATIPESAPRAGPTRSAGTSSRN----------PASRPPASGRGERAPPAKNTSPGP 113
Query: 535 LPKAPSESARGPPGPTD--GAKVH-EDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDP 591
+ S PGP G ++ E++ + A E + S G + + P G
Sbjct: 114 VSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS 173
Query: 592 ----------GNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGA 641
G G A S++ P S S+ S PS + + P GG
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 233
Query: 642 GHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPK--CPD 699
S ++ A P + G P P +P P+G L+P P
Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK-PKGL----QALRPPQVTPP 288
Query: 700 TLQSREGLGRMESFLTLESEKSD-----FPP-----TPVAEVAPKAQEGESTLEIRKMGS 749
+ LG + S S PP TP+ P + + L +
Sbjct: 289 RKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348
Query: 750 CDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTALILDQDQQGIPSCP 809
L T P P P A + PP + + + + + Q PS
Sbjct: 349 SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP-IQVPHSLTSPSLQAPPSPL 407
Query: 810 GEGWIRGAAS--EWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSP-SHPGFK 866
++ S L ++ L S Q + S+ + + PP++ +P S P
Sbjct: 408 ALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP 467
Query: 867 DQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTLSDTPTSSPTDMVWESS 926
S P+ + L H Q + + Q P +L P + + + S
Sbjct: 468 PLQTSLSPAVSPLS----SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Query: 927 LTEESELSAPTRQKLPALGEKRPEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKETCCT 986
T + L+ P + LP+L + A + + P
Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA------------------ 565
Query: 987 GQGPNKSQQALADALEEGSQHEEACQRHPGASEAADGCSPLWGLSKREMASGNTGEAPPC 1046
P Q + + + P + A PL GL ++ T PP
Sbjct: 566 ---PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLAT--PPPQ 620
Query: 1047 QPDSVAL--LDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQQKMECWA 1104
P +AL L A P PA P SP TP+ AP A Q P P Q
Sbjct: 621 APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 680
Query: 1105 TSDAESPKLLASFPSAGEQGGEAGAAETGGSAGAGDPGKQQA-PEKPGEATLSCGLLQTE 1163
S SP A+ PS A + S A P A P L+ LQ
Sbjct: 681 ASPPVSPS--ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP 738
Query: 1164 HCLTSGEEASTSALRESCQAEHPMASCQDALLPARELGGIPRSTMDFSTHQAVPDPKELL 1223
+ S SA P+ + +P +P S + A P P+
Sbjct: 739 PSPPASPPMSPSATPP--PRVPPLLAAPPLQVPPSPPASLPMSPL------AKPPPQ--- 787
Query: 1224 LSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPCPVGEPPLALENAAS 1283
PP +A P L A+ G + S++ P +P +P P P LA
Sbjct: 788 --APPALATPPLQALPSPPASFPG---QAPFSPSASLPMSPLATPPPQAPPVLA------ 836
Query: 1284 LKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATG 1343
APLLQ + P +QA P+ T GP S+ LA G
Sbjct: 837 --------APLLQVPPSPPASPTLQA----PRRPPTPGPDTSVSGPRLTLALAPGPPPPP 884
Query: 1344 EEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIATL 1402
++ SG +AG ++ T E G S G GG S A L
Sbjct: 885 SRSPSST------LSGPDLAGHSSSATSTPEELRGYDS-----GPEGGAAASPPPDAEL 932
Score = 63.9 bits (154), Expect = 2e-09
Identities = 141/621 (22%), Positives = 198/621 (31%), Gaps = 105/621 (16%)
Query: 11 QRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSASLDP 70
QR S SA P + + TP +P H S+
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAH----------------PSQPKPKGLQ 278
Query: 71 CLVSPEVTEPRKDPQGARGP-EGSLLPSPPPSQEREHP-----SSSMPF-AECPPEGCLA 123
L P+VT PRKD A GP S L +P PS + P +++ P A PP LA
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA 338
Query: 124 SP-------AAAPEDGPQTQSPRREPAPNAPGDIAA---AFPAERDSSTPYQEIAAVPSA 173
+P +AP SP P AP + P + P Q ++ S
Sbjct: 339 TPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSP 398
Query: 174 GRERQPKE---EGQKSSFSFSSGIDQSP----GMSPVPLREPMKAPLCGEGDQPGGFESQ 226
+ P +++ S S Q+ MSP + + +P P +S
Sbjct: 399 SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP---DSP 455
Query: 227 EKEAAGGFPPAESRQGVASVQVTP-EAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRA 285
+A P + Q S V+P +P S++ SP P++ + P
Sbjct: 456 PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQ 515
Query: 286 SDRERGQGEAPPQYL-TDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHA 344
S + PP L T LE L + P + +AP PH
Sbjct: 516 SSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP-----------------LTTPHL 558
Query: 345 ELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVS 404
E P P PA P +A + P+T P A P GLP
Sbjct: 559 ETP---PCPAPCP------LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP 609
Query: 405 PEPSLLTPTEEAHPASSLASFPAAQ--------IPIAVEEPGSSSRESVSKAGMPVSADA 456
P L TP +A P +L A P+A P + + +V P S
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669
Query: 457 AKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPP 516
+ V P P P+ +P + +V P P
Sbjct: 670 SPPV----------------QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 713
Query: 517 PLPKEQSHEVQPGAPP----PPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSP 572
P P S P APP PPL PS A P P + P +A + P
Sbjct: 714 P-PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSP---SATPPPRVPPLLAAPPLQVP 769
Query: 573 GDSPGGKEEAP--EPPDGGDP 591
P +P +PP P
Sbjct: 770 PSPPASLPMSPLAKPPPQAPP 790
Score = 60.5 bits (145), Expect = 2e-08
Identities = 193/883 (21%), Positives = 285/883 (32%), Gaps = 143/883 (16%)
Query: 1197 ARELGGIPRSTMDFSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAV 1256
A GGI +T+ S +A P S P P A+ RG K
Sbjct: 59 AERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPP---------ASGRGERAPPAKNT 109
Query: 1257 SSADPRAPGES-----PCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASS 1311
S +PG + P P+G+ L + ++ + AP +AG
Sbjct: 110 SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGAR-------- 161
Query: 1312 GSPKARTTEGPVDSMPCLDRMPLLAKGKQATGEEKAAT--APGAGAKASGEGMAGDAAGE 1369
R T GP P P +A+ +A G E AP A + EG +
Sbjct: 162 -----RDTSGPTPGTPS----PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 212
Query: 1370 TEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGE 1429
+E S P+ + GG+ + + + + P L + A G
Sbjct: 213 SEHSTTEPS-PAARRRPSAGGGLQRPASRSLSSSATP--------------LSSPARSGP 257
Query: 1430 KA-GAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPARLQVEKKQQLAGEAEISHLA 1488
A G R+ +P G + L PP V A PA L LA + A
Sbjct: 258 SARGTPRAPAHPSQPKPKGLQALR--PPQVTPPRKDAAPA-LGPLSSSPLATPSPSGTKA 314
Query: 1489 LQDPASDKLLGPAGLTWERNLPGAG---VGKEMAGVPPTLREDERPEG------------ 1533
P D P T + P A + PP+L+ P
Sbjct: 315 RPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTT 374
Query: 1534 -PGAAWPGLEGQAYSQLERSRQELA-SGLPSPAATQELPVERAAAFQVAPHSHGEEAVAQ 1591
P A P L+ Q+ S + PSP A L + +H ++
Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434
Query: 1592 DRIPSGKQHQETSACDSPHGEDGPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPW 1651
+ + A P D P A +P P T SP L+ P
Sbjct: 435 RQTQASLTSPSRPASTPP---DSPPLQAPLSLPASPPLQTSL-SPAVSPLSSPLTIHPLQ 490
Query: 1652 TLDTLGGERRPGVTAGI----LEMRNALGNQSTPAPPTGEVADTPLE--PGKVAGAAGEA 1705
L +L + + LE +++L S PP + PLE P A
Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPAS-LTTPPLENLPSLAPPPLQTA 549
Query: 1706 EGDITLSTAETQACASG---DLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTA 1762
+T ET C + P + T + P PA + +P ++G
Sbjct: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA--SPPLQGL- 606
Query: 1763 ALHGDSPARPQQAKEQPGPERP----IPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHT 1818
P+ P P P+ P +P + +PP P + P L
Sbjct: 607 ------PSPPLSPLATPPPQAPPXLALPP------LQAPPSPPAS--PPL---------- 642
Query: 1819 DRESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAA-PADLESP 1877
SP PS P P A ++ S SP A + P+A P P
Sbjct: 643 ---SPLATPS--PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 697
Query: 1878 TLAASSYHGDVVGQVSTDLIAQSISP-------AAAHAGLPPSA-AEHIVSPSAPAGDRV 1929
+LAA S + + P AA +PPS A +SPSA RV
Sbjct: 698 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
Query: 1930 E---ASTPSC--PDPAKDLSRSSDSEEAFETPES--TTPVKAPPAPPPP--------PPE 1974
A+ P P P L S ++ + P + T P++A P+PP P
Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 817
Query: 1975 VIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPS 2017
+P ++T PP P + + VP P + +P RPP+
Sbjct: 818 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 860
Score = 56.6 bits (135), Expect = 4e-07
Identities = 239/1049 (22%), Positives = 341/1049 (32%), Gaps = 174/1049 (16%)
Query: 414 EEAHPASSLASFPAAQIPIAVEEPGSSSRES----VSKAGMPVSADAAKEVVDAGLV--G 467
E A PA + + P V PG +S + + + G+ +SA+ E V G
Sbjct: 101 ERAPPAKNTSPGP-------VSSPGRASGTTRPGPLGQKGLRISAE---ETVARGKATEA 150
Query: 468 LERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQ 527
+R G++ + PG P+P+ R TE +P P P +
Sbjct: 151 PKRSALSAGARRDTSGPTPG-TPSPAMARRSRAAGTEVGLP-RPAPSARPRPPTEGPRKS 208
Query: 528 PGAPPPPLPKAPSESARGPPGPTDGAK--VHEDSTSPAVAKEGSRSPGDSPGGKEEAPEP 585
+ PS +AR P G + +S A G S G AP
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268
Query: 586 PDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHS--AQPPRKGGAGH 643
P P LQ + R P+V + P DA P S S A P G
Sbjct: 269 PSQPKPKGLQ--------ALRPPQV-----TPPRKDAAPALGPLSSSPLATPSPSGTKAR 315
Query: 644 TDGPHSQTAEADASGLPHK--LGEEDPVLPPVPDGAGE-PTVPEGAIWEGSGLQP----- 695
P A + LP L P+ PP P T+P S P
Sbjct: 316 PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP 375
Query: 696 --KCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEG------ESTLEIRKM 747
+ P +LQ+ + S L S PP+P+A + +A ++T M
Sbjct: 376 PMQAPPSLQTIPPIQVPHS---LTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTM 432
Query: 748 GSCDGEGLLTSPDQPRGPACDASRQEFHAGVP-HPPQGENLAADLG-LTALILDQDQQGI 805
+ LTSP +P D+ + +P PP +L+ + L++ + Q +
Sbjct: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL 492
Query: 806 PSCPGEGWIRGAASE-WPLLSSEKHLQPSQAQ-PETSI----FDVLKEQAQPPENGKET- 858
S +S P L ++ L P Q P S+ + L A PP
Sbjct: 493 SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP 552
Query: 859 -------SPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQ-ALGSELQSQLPKGTL 910
+P P A S + P P+ +++ T Q AL S LP L
Sbjct: 553 LTTPHLETPPCPAPCPLQAPPSPLTTP-PPETPSSIATPPPQAPPALASPPLQGLPSPPL 611
Query: 911 SDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRPEGACGDGQSSRVSPPAADVLK 970
S T P AP LP L + SPPA+ L
Sbjct: 612 SPLATPPP---------------QAPPXLALPPL-------------QAPPSPPASPPLS 643
Query: 971 DFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQHEEACQRHPGASEAADGCSPLWGL 1030
+ + Q PN L A S + P + A+ SP
Sbjct: 644 PLATP----------SPQAPNALAVHLLQA--PFSPPPSPPVQAPFSPPASPPVSP---- 687
Query: 1031 SKREMASGNTGEAPPCQ-PDSVAL--LDAVPCLPALAPASPGVTPTQDAPETEACDETQE 1087
PP Q P S+A L P PA P SP TP AP A Q
Sbjct: 688 ----------SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQV 737
Query: 1088 GRQQPVPAPQQKMECWATSDAESPKLLASFPSAGEQGGEAGAAETGGSAGAGDPGKQQAP 1147
P P M AT P LLA+ P Q + A S A P QAP
Sbjct: 738 PPSPPASPP---MSPSATPPPRVPPLLAAPPL---QVPPSPPASLPMSPLAKPP--PQAP 789
Query: 1148 EKPGEATLSCGLLQTEHCLTSGEE--ASTSALRESCQAEHPMASCQDALLPARELGGIPR 1205
P AT L + G+ + +++L S A P + P ++ P
Sbjct: 790 --PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 847
Query: 1206 STMDFSTHQAVPDP-KELLLSGPPEVAA----PDTPYLHVDSAAQRGAEDSGVKAVSSAD 1260
++ + P P + +SGP A P P S+ G + +G + +++
Sbjct: 848 ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 907
Query: 1261 PRA-----PGESPCPVGEPPLALENAAS--LKLFAGSLAPLLQPGAAGGEIPAVQASSGS 1313
P G PP E AA G PL GA G +P A
Sbjct: 908 PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA---- 963
Query: 1314 PKARTTEGPVDSMPCLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGS 1373
T G D + + + G E A APGA G +G A G+
Sbjct: 964 ----TGPGSADGLCTI---------YETEGPESATPAPGALDPGPSPGTSGGKAAAGAGA 1010
Query: 1374 MERMGEPSQDPKQGTSGGVDTSSEQIATL 1402
G S+ PKQ G + + Q + +
Sbjct: 1011 ----GASSRSPKQARLGELPLGALQASVV 1035
Score = 54.3 bits (129), Expect = 2e-06
Identities = 90/364 (24%), Positives = 119/364 (32%), Gaps = 52/364 (14%)
Query: 73 VSPEVTEPRKDPQGARGPEGSLLPSPPP----SQEREHPSSSMPFAECPPEGCLASPAAA 128
VSP T P + P P + PSPP S P + P PP SP A+
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744
Query: 129 PEDGPQTQSPRREP----AP--NAPGDIAAAFPAERDSSTPYQ---EIAAVPSAGRERQP 179
P P P R P AP P A+ P + P Q +A P P
Sbjct: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804
Query: 180 KEEGQKSSFSFSSGIDQSPGMSPVPLREP-MKAPLCGEGDQPGGFESQEKEAAGGFPPAE 238
++ FS S+ + SP +P P P + APL P + + P +
Sbjct: 805 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 864
Query: 239 S-----RQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQG 293
+ R +A P P+ + T S L P++ S E G
Sbjct: 865 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL-AGHSSSATSTPEELRGYDSGPEGGAA 923
Query: 294 EAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSP 353
+PP D E L ACH + G AP A P A LPW
Sbjct: 924 ASPP----PDAE-LAACHPAAWSRGPAPPLAFRGA-------------PGAPLPW----- 960
Query: 354 ALVPEAGGSGKEALDTIDVQGHPQTGM-------RGTKPNQVVCVAAGGQPEGGLPVSPE 406
P G + L TI P++ G P AA G G SP+
Sbjct: 961 --PPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPK 1018
Query: 407 PSLL 410
+ L
Sbjct: 1019 QARL 1022
Score = 53.5 bits (127), Expect = 3e-06
Identities = 146/609 (23%), Positives = 197/609 (32%), Gaps = 119/609 (19%)
Query: 124 SPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEG 183
S AA E G +P P P G + A S+T PS R+P G
Sbjct: 180 SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE-------PSPAARRRPSAGG 232
Query: 184 ---QKSSFSFSSGID--QSPGMSPVPLREPMKAPLCGEGDQPGGFES--------QEKEA 230
+ +S S SS SP S R +AP +P G ++ K+A
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292
Query: 231 AGGFPPAESR-------QGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMA-PIPQDPA 282
A P S G + V P AA T A L SP P+A P+P P
Sbjct: 293 APALGPLSSSPLATPSPSGTKARPVPPPDNAA----TPLPATLPPSP--PLATPLPLAP- 345
Query: 283 PRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLP 342
P S APP T LP + +A + + P +P
Sbjct: 346 PSPS--------APPSLQT----------LPSPPATPPSQAPPSMTTPPMQAPPSLQTIP 387
Query: 343 HAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLP 402
++P L SP+L +L G P ++ T L
Sbjct: 388 PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPT--LQAT--------------HSFLT 431
Query: 403 VSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRE-SVSKAGMPVSADAAKEVV 461
+SP + + T + PAS+ P Q P+++ P S + S+S A P+S+ +
Sbjct: 432 MSPRQTQASLTSPSRPASTPPDSPPLQAPLSL--PASPPLQTSLSPAVSPLSSPLTIHPL 489
Query: 462 DA-GLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPL-- 518
A + + L S P + PS Q L T + P + PPPL
Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL-PSLAPPPLQT 548
Query: 519 ---PKEQSHEVQPGAPPP------------PLPKAPSESARGPPGPTDGAKVHEDSTSPA 563
P H P P P P P+ PS A PP PA
Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP-----------QAPPA 597
Query: 564 VAK---EGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSS 620
+A +G SP SP PP P LQ S S P L+ PS
Sbjct: 598 LASPPLQGLPSPPLSPLATPPPQAPPXLALP-PLQAPPSPPASPPLSP------LATPSP 650
Query: 621 DAESR------DHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVP 674
A + P S PP + P + S P L +PP P
Sbjct: 651 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
Query: 675 DGAGEPTVP 683
A P P
Sbjct: 711 P-ASPPMSP 718
Score = 42.4 bits (98), Expect = 0.007
Identities = 118/538 (21%), Positives = 170/538 (31%), Gaps = 107/538 (19%)
Query: 131 DGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIA-----AVPSAGRERQPKEEGQK 185
D + + R PA APG + P P A A + GR+ + G
Sbjct: 6 DKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI 65
Query: 186 SSFSFS-----SGIDQSPGMSPVPLREPM-KAPLCGEGDQ--------PGGFESQEKEAA 231
+ +G +S G S R P + P G G++ PG S + +
Sbjct: 66 GGATIPESAPRAGPTRSAGTSS---RNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG 122
Query: 232 GGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERG 291
P ++G+ A A + + SA+ + P P P+P + R R
Sbjct: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
Query: 292 QGEAPPQYLTDDLEFLRACHLPRSNSGA-------APEAEVNAASQESCQQPVGAYLPHA 344
G LPR A P V++AS+ S +P A
Sbjct: 183 AG--------------TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 228
Query: 345 ELPWGLPSPA---LVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGL 401
GL PA L A A +G P+ ++P +P+G
Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP----------KPKGLQ 278
Query: 402 PVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVV 461
+ P P + P ++A PA P + P+A P S +KA D A +
Sbjct: 279 ALRP-PQVTPPRKDAAPALG----PLSSSPLATPSP------SGTKARPVPPPDNAATPL 327
Query: 462 DAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKE 521
A L + L P P PSP P PP P
Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP----------------PATPPSQAP-- 369
Query: 522 QSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEE 581
P PP+ PS P +V TSP++ ++P SP
Sbjct: 370 ------PSMTTPPMQAPPSLQTIPP------IQVPHSLTSPSL-----QAP-PSPLALSS 411
Query: 582 APEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSS---DAESRDHPSSHSAQPP 636
G P LQ S S R + S+P+S D+ P S A PP
Sbjct: 412 LQATTSLGSP-TLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 89.7 bits (221), Expect = 4e-17
Identities = 282/1229 (22%), Positives = 364/1229 (29%), Gaps = 207/1229 (16%)
Query: 17 QTPRSAQPPGNSQNIKRKQQDT--PGSPDHRDASSI-------GSVGLGGFCTASESSAS 67
Q P + P N Q + + D PG P I GS G G C
Sbjct: 90 QPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGIC-------- 141
Query: 68 LDPCLVSPEVTEPRKDPQ------------GARGPEGSLLPSPPPSQEREHPSSSMPFAE 115
+ C P+ P+ D G GP G P PP S P +
Sbjct: 142 -ESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQ 200
Query: 116 CPPEGCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGR 175
PP P A GP P PG I + PA +D + GR
Sbjct: 201 GPP----GEPGQAGPSGP----------PGPPGAIGPSGPAGKDGES-----------GR 235
Query: 176 ERQPKEEGQKS--SFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGG 233
+P E G +GI PGM + GE PG G
Sbjct: 236 PGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEK-GETGAPGLKGENGLPGENG 294
Query: 234 FPPAESRQGVASVQVTPEAPAAA-QQGTESSAVLEKSPLKPMAP----IPQDPA------ 282
P +G + P P AA +G + + + P P P P P
Sbjct: 295 APGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVG 354
Query: 283 PRASDRERG----QGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVG 338
P S G +GE PQ P N + E+ A +G
Sbjct: 355 PAGSPGSNGAPGQRGEPGPQ---GHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMG 411
Query: 339 AYLPHAELPWGLP-SPALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQP 397
A P P G +P L AG GK +G P G RG + + G +
Sbjct: 412 ARGPPG--PAGANGAPGLRGGAGEPGKNG-----AKGEP--GPRGERGEAGIPGVPGAKG 462
Query: 398 EGGLPVSP----------------EPSLLTPTE------EAHPASSLASFPAAQIPIAVE 435
E G SP P P E PA + A A
Sbjct: 463 EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAG 522
Query: 436 EPGSSSRESV----SKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEH-PEGDPGEVP 490
EPG R+ V GMP S G G + + G G P G PG +
Sbjct: 523 EPG---RDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMG 579
Query: 491 APSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPT 550
P P+ + + PG P P P ++ E P PP P + GPPGP
Sbjct: 580 FPGPKGN-DGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQ 638
Query: 551 -------DGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFS 603
G E+ +G +PGGK +A P + G PG + +
Sbjct: 639 GLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGA 698
Query: 604 SKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAE---ADASGLP 660
PE GK P + P +GG G + GP E A G+P
Sbjct: 699 GPPGPEGGKGAAGPPGPPGAA--GTPGLQGMPGERGGLG-SPGPKGDKGEPGGPGADGVP 755
Query: 661 HKLGEEDPVLPPVPDG-AGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESE 719
K G P P P G AG+P +G G P P R G
Sbjct: 756 GKDGPRGPTGPIGPPGPAGQPGD------KGEGGAPGLPGIAGPRGSPG---------ER 800
Query: 720 KSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQ--PRGPACDASRQEFHAG 777
PP P Q GE G+G +P + GP G
Sbjct: 801 GETGPPGPAGFPGAPGQNGEP----------GGKGERGAPGEKGEGGP----------PG 840
Query: 778 VPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQP 837
V PP G A G + + ++G P PG GA S + P P
Sbjct: 841 VAGPPGGSGPAGPPGPQGV---KGERGSPGGPGAAGFPGARGLPGPPGSNGN--PGPPGP 895
Query: 838 ETSIFDVLKEQAQPPENGKETSPSHPGFKDQGADSSQIHVPVEP--QEDNNLPTHGGQEQ 895
S + P G +P PG D+ Q P Q P G
Sbjct: 896 SGS----PGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAG 951
Query: 896 ALGSELQSQLPKGTLSDTPTSSPTDMVWESSLTEESELSA----PTRQKLPALGEKRPEG 951
G+ + P G + P + ES + LS P Q LP L
Sbjct: 952 ITGARGLAG-PPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGL------- 1003
Query: 952 ACGDGQSSRVSPPAADVL--KDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQHEE 1009
A G+ R P +D L +D S G R E G + + +
Sbjct: 1004 AGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGD 1063
Query: 1010 ACQRHPGASEAADGCSPLWGLSKREMASGNTGEAPPCQPDSVALLDAVPCLPALAPASPG 1069
+ P A G + G + G+ GE + P P AP SPG
Sbjct: 1064 RGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPG-APGSPG 1122
Query: 1070 VTPTQDAPETEACDETQEGRQQPVPAPQQKMECWATSDAESPKLLASFPSAGEQGGEAGA 1129
Q A + G + PV P TS P G G
Sbjct: 1123 PAGQQGAIGSPG----PAGPRGPV-GPSGPPGKDGTSGHPGP--------IGPPGPRGNR 1169
Query: 1130 AETGGSAGAGDPGKQQAPEKPGEATLSCG 1158
E G G PG+ P PG CG
Sbjct: 1170 GERGSEGSPGHPGQPGPPGPPGAPGPCCG 1198
Score = 55.1 bits (131), Expect = 1e-06
Identities = 245/1034 (23%), Positives = 308/1034 (29%), Gaps = 244/1034 (23%)
Query: 1114 LASFPSAGEQGGEAGAAETGGSAGA-GDPGKQQAPEKPGEATLSCGLLQTEHCLTSGEEA 1172
LA +P G G T G G+ G PG Q P +PG+A SG
Sbjct: 169 LAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAG------------PSGPPG 216
Query: 1173 STSALRESCQAEHPMASCQDALLPARELGGIPRSTMDFSTHQAVPDPKELLLSGPPEVAA 1232
A+ S P ++ P R P E L GPP +
Sbjct: 217 PPGAIGPS----GPAGKDGESGRPGR--------------------PGERGLPGPPGIKG 252
Query: 1233 PDTPYLHVDSAAQRGAED-SGVKAVSSAD----------------PRAPGESPCPVGEPP 1275
P RG + +G K + A P P +P G P
Sbjct: 253 PAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRP- 311
Query: 1276 LALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMP-- 1333
L AA + G+ QPG G P GSP A+ GP S P + P
Sbjct: 312 -GLPGAAGARGNDGARGSDGQPGPPGP--PGTAGFPGSPGAKGEVGPAGS-PGSNGAPGQ 367
Query: 1334 ---------LLAKGKQAT----------GEEKAATAPGAGAKASGEGMAGDA-AGETEGS 1373
A+G GE A PGA G G A A G
Sbjct: 368 RGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGL 427
Query: 1374 MERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGEKAGA 1433
GEP ++ +G G E A + G P + K GA PG A
Sbjct: 428 RGGAGEPGKNGAKGEPGPRGERGE--AGIPGVPGAKGEDGKDGSPGEPGANGLPG--AAG 483
Query: 1434 GRSAVGKDLTRPLGPEKLLD--GPPGVDVTLLPAPPARLQVEKKQQLAGEAEISHLALQD 1491
R A G P GP + GP G PA P + AGE
Sbjct: 484 ERGAPG--FRGPAGPNGIPGEKGPAGERGAPGPAGP--------RGAAGE---------- 523
Query: 1492 PASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQLER 1551
P D + G G+ PG G P + E RP PG + P
Sbjct: 524 PGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGP------------ 571
Query: 1552 SRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSGKQHQETSACDSPHG 1611
Q G P P P + + P G + P GK + + P G
Sbjct: 572 RGQPGVMGFPGPKGNDGAPGKNGE--RGGPGGPGPQG------PPGKNGE--TGPQGPPG 621
Query: 1612 EDGP-GDFAHTGVPG-----HVPRSTCAPSPQREVLTVPEANSEPWTLDTLG-------- 1657
GP GD TG PG +P T P + P + G
Sbjct: 622 PTGPGGDKGDTGPPGPQGLQGLP-GTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAP 680
Query: 1658 GERRPGVTAGILEMRNALGNQSTPAPPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQ 1717
GER P AG +R G P P G+ A P P AG G +G
Sbjct: 681 GERGPPGLAGAPGLR---GGAGPPGPEGGKGAAGPPGPPGAAGTPG-LQGMPGERGGLGS 736
Query: 1718 ACASGDLPEAGTTRTFSV--------VAGDLVLPGSCQDPACSDK--APGMEGTAALHGD 1767
GD E G V G + PG P + APG+ G A G
Sbjct: 737 PGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGS 796
Query: 1768 S--------------PARPQQAKEQPGP-ERPIPAGDGK---VCVSSPPEPDETHDPKLQ 1809
P P Q E G ER P G+ V+ PP P
Sbjct: 797 PGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPP-- 854
Query: 1810 HLAPEELHTDRESPR-------PGPSMLPSVPKKDA----PRVMDKVTSDETRGAEGTES 1858
P+ + +R SP PG LP P + P D G G
Sbjct: 855 --GPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTG 912
Query: 1859 SPVADDIIQP----AAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSA 1914
+P + + P P + SP +G I+ A AG PP
Sbjct: 913 APGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLG-------IAGITGARGLAG-PPGM 964
Query: 1915 AEHIVSPSAPAGDRVEASTP----------------------SCPDPAKDLSRSSDSEEA 1952
SP P G + E+ P + +P +D + SD
Sbjct: 965 PGPRGSP-GPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPG 1023
Query: 1953 --------FETPESTTPVKAPPAP--PPPPPEVIP------EPEVSTQPPPEEPG-CGSE 1995
+ E+ +P AP AP P PP V P E P PG GS
Sbjct: 1024 RDGSPGGKGDRGENGSP-GAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSR 1082
Query: 1996 TVPVPDGPRSDSVE 2009
P P GPR D E
Sbjct: 1083 GAPGPQGPRGDKGE 1096
Score = 38.1 bits (87), Expect = 0.13
Identities = 41/173 (23%), Positives = 57/173 (32%), Gaps = 20/173 (11%)
Query: 514 PPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAV-AKEGSRSP 572
P P +P + V P P P + +GP G + + P + + GS
Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGS 134
Query: 573 GDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHS 632
PG E P P P ++ K VG P+
Sbjct: 135 PGPPGICESCPTGPQNYSP------QYDSYDVKSGVAVG---------GLAGYPGPAGPP 179
Query: 633 AQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEG 685
P G +GH P S + G P + G+ P PP P GA P+ P G
Sbjct: 180 GPPGPPGTSGHPGSPGSPGYQ----GPPGEPGQAGPSGPPGPPGAIGPSGPAG 228
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 89.0 bits (219), Expect = 6e-17
Identities = 192/885 (21%), Positives = 301/885 (34%), Gaps = 93/885 (10%)
Query: 1771 RPQQAKEQPGPERPI--PAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPS 1828
+ + K++P P+ P+ AG G +T + ++ T + P PS
Sbjct: 70 KKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 129
Query: 1829 MLP-SVPKKDAPRVMDKVTSDETR---------GAEGTESSPVADDI--IQPAAPADLE- 1875
+ P S K+ ++K T+ ET+ +G E + A + I+ + DL
Sbjct: 130 LPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP 189
Query: 1876 -SPTLAASSYHGDVVGQVSTDLIAQSISPAAAH--AGLPPSAAEHIVSPSAPAGDRVEA- 1931
S LA + + + + +P A P SAP + A
Sbjct: 190 TSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 249
Query: 1932 -STPSCPDPAKDLSRSSDSEEAFETPESTTPV----------KAPPAPPPPPPEVIPEPE 1980
+T S P K+ + ++ E A TP+ P K+ P P P P+
Sbjct: 250 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 309
Query: 1981 VSTQPPPEEPGCGSETVPV-PDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLD 2039
T P P E P P P + E +P P + +A KP ++
Sbjct: 310 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA---PKKPAPTTPKEPAP 366
Query: 2040 FDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASS 2099
E T T EP + K +T P +T S + + ++
Sbjct: 367 TTPKEPAPT-TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS---PTT 422
Query: 2100 SGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDE 2159
+ P A +T A +T K P P TTKKP T P + P E
Sbjct: 423 TKEPAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPAPTTTKKPAPTTPKEPAPTTPKE 481
Query: 2160 ------ESLVPSG-ENLASETKTESAKT--EGPSPALLEE----TPLEPA-VGPKAACPL 2205
+ L P+ E LA T + A T E +P EE TP EPA PKAA P
Sbjct: 482 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN 541
Query: 2206 DSESAEGVVP----PASGGGRVQNSPPVGRKTLPLTTAP----EAGEVTPSDSGGQEDSP 2257
+ P P + +P T P TAP E TP +E +P
Sbjct: 542 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 601
Query: 2258 AKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPAS 2317
+ + + DK + + P T K K P P L +
Sbjct: 602 T---TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 658
Query: 2318 PPRSPAEPNDIPIA-KGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDE 2376
P+ PA P KG + DK + T+ + +P P++ P+T
Sbjct: 659 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 718
Query: 2377 SVDPFKT--SSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPA-KKKKTPLKTDTFRV 2433
+ T ++K P++ KSP SA + +P KTP T
Sbjct: 719 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT 778
Query: 2434 KKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKL-AVTNQKWTCMTVDLEADK 2492
+ ++ D + T A P+ + T E K+ A T Q + T D K
Sbjct: 779 TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFK 838
Query: 2493 QDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFD 2552
+ + L+ V TK + T E+ M K P++ PK +A +
Sbjct: 839 ITTLKTTTLAPKVTTTKKTITTTEI----------MNK-----PEETAKPKDRAT----N 879
Query: 2553 TSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPR 2597
+ +P P + + PT S ++ + + P PR
Sbjct: 880 SKATTPKPQKPTKAPKKPT-----STKKPKTMPRVRKPKTTPTPR 919
Score = 77.8 bits (190), Expect = 1e-13
Identities = 155/732 (21%), Positives = 241/732 (32%), Gaps = 70/732 (9%)
Query: 1628 PRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGE 1687
P +T P+P P EP T P A + A PAP T +
Sbjct: 264 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 323
Query: 1688 VADTPLEPGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQ 1747
TP P + A E +T + A + P T + + P + +
Sbjct: 324 -EPTPTTPKEPAPTTKEPAP----TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTK 378
Query: 1748 DPACS---DKAPGMEGTAALHGDSPARPQQAKEQPG-PERPIPAGDGKVCVSSPPEPDET 1803
+P+ + + AP +A PA P K P P+ P P + ++P EP T
Sbjct: 379 EPSPTTPKEPAPTTTKSAPTTTKEPA-PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 437
Query: 1804 HDPKLQHLAPEE-LHTDRESPRPGPSM--LPSVPKKDAPRVMDKVTSDETRGAEGTESSP 1860
K P+E T + P P + P+ PK+ AP T ET + +P
Sbjct: 438 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP-----TTPKETAPTTPKKLTP 492
Query: 1861 VADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHI-V 1919
+ + P P E P + T + +P A P + E
Sbjct: 493 TTPEKLAPTTP---EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 549
Query: 1920 SPSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEP 1979
+P PA + P+ P + + + P TTP K PAP P EP
Sbjct: 550 TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK--PAPKELAPTTTKEP 607
Query: 1980 EVST--QPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYN 2037
+T +P P P + T P P + E +P P + E P
Sbjct: 608 TSTTCDKPAPTTPKGTAPTTPKEPAPTTPK-EPAP-TTPKGTAPTTLKEPAPTTPKKPAP 665
Query: 2038 LDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDG 2096
+ T + + +E T ++ + P + T + S+
Sbjct: 666 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 725
Query: 2097 ASSSGNPEAVALAPDAYSTGSSSASSTLKRTK-KPRPPSLKKKQTTKKPTETPPVKETQQ 2155
+++ P + +PD ST SA T K + P+ P + TTK P T P T
Sbjct: 726 PTTTKEPTTIHKSPDE-STPELSAEPTPKALENSPKEPGV---PTTKTPAATKPEMTTTA 781
Query: 2156 EPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP 2215
++ ET T + K + E+T +ES
Sbjct: 782 ---KDKTTERDLRTTPETTTAAPKMTKETATTTEKT---------------TESKITATT 823
Query: 2216 PASGGGRVQNSPPVGRKTLPLTT-APEA----GEVTPSDSGGQEDSPAKGLSVRLEFDYS 2270
Q++ P TL TT AP+ +T ++ + + AK +
Sbjct: 824 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT 883
Query: 2271 EDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNT-PASPPRS-------- 2321
K + P + KKP +R+PK TP K+ +T P P S
Sbjct: 884 TPKPQKPTKAPKKPTST---KKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 940
Query: 2322 -PAEPNDIPIAK 2332
PN P +K
Sbjct: 941 TTTRPNQTPNSK 952
Score = 77.0 bits (188), Expect = 3e-13
Identities = 130/630 (20%), Positives = 201/630 (31%), Gaps = 65/630 (10%)
Query: 19 PRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSASLDPCLVSPEVT 78
P S P + + TP P S + T ++ A P +P T
Sbjct: 224 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 283
Query: 79 EPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSP 138
K+P P P + P+ + P P +P E P T+ P
Sbjct: 284 ---KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 340
Query: 139 R----REPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGI 194
+EPAP AP A P E +TP + P+ +E P + + + S
Sbjct: 341 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKE---PAPTTTKEPSPTTPKEPAPTTTKSAP 397
Query: 195 DQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPA 254
+ +P + P +P ++E PA + TP+ PA
Sbjct: 398 TTTKEPAPTTTKSAPTTP-----KEPSPTTTKEPAPTTPKEPAPTTP-KKPAPTTPKEPA 451
Query: 255 AAQQGTESSAVLEK-SPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTDDLEFLRACHLP 313
+ +K +P P P P P A + P+ L A P
Sbjct: 452 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 511
Query: 314 RSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPE-AGGSGKEALDTIDV 372
+ PE +E A P+ P+P E A + KE T
Sbjct: 512 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE---PAPTTPKEPAPTTPKEPAPTTPK 568
Query: 373 QGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPI 432
+ P T +GT P + +P P P P L PT P S+ PA P
Sbjct: 569 ETAPTT-PKGTAPTTL------KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP- 620
Query: 433 AVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHP----EGDPGE 488
+ + K P + ++ + KG P E P
Sbjct: 621 ------KGTAPTTPKEPAPTT---------------PKEPAPTTPKGTAPTTLKEPAPTT 659
Query: 489 VPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPG 548
P+P+E T+ P P PKE + P P P PK P+ + P
Sbjct: 660 PKKPAPKELAP-TTTKGPTSTTSDKPAPTTPKETA-PTTPKEPAPTTPKKPAPTTPETPP 717
Query: 549 PTDGAKVHEDSTSPAVAKEGS---RSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSK 605
PT + ++P KE + +SP +S P P + G + +
Sbjct: 718 PTT-----SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 772
Query: 606 RDPEVGKDELSKPSSDAESRDHPSSHSAQP 635
PE+ K +++ + R P + +A P
Sbjct: 773 TKPEMTTTAKDK-TTERDLRTTPETTTAAP 801
Score = 74.7 bits (182), Expect = 1e-12
Identities = 160/747 (21%), Positives = 249/747 (33%), Gaps = 94/747 (12%)
Query: 1781 PERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESP-----RPGPSML----P 1831
P+ P P + ++P EP T E T +S P P+ P
Sbjct: 213 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 272
Query: 1832 SVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPA-------APADLESPTLAASSY 1884
+ PK+ AP + T+ A T P +PA AP + PT
Sbjct: 273 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 332
Query: 1885 HGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHI-VSPSAPAGDRVEASTPSCP-DPAKD 1942
+ + + +P A P + E +P PA + +P+ P +PA
Sbjct: 333 PAPTTKEPAPTTPKEP-APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 391
Query: 1943 LSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVST--QPPPEEPGCGSETVP-- 1998
++S+ + + P TT AP P P P EP +T +P P P + T P
Sbjct: 392 TTKSAPTTT--KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 449
Query: 1999 -VPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS 2057
P P+ + + P+ K A + L E + T + +
Sbjct: 450 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP--TTPEKPA 507
Query: 2058 DAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTG 2116
+E T + T + P + T ++ + ++ P A +T
Sbjct: 508 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 567
Query: 2117 SSSASSTLKRT-----KKPRPPSLKKKQ-------TTKKPTETPPVKETQQEPDEESLVP 2164
+A +T K T K+P P + KK TTK+PT T K P +
Sbjct: 568 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 627
Query: 2165 SGENLASETKTESAKT-EGPSPALLEE----TPLEPAVGPKAACPLDSESAEGVVP---- 2215
E + K + T +G +P L+E TP +PA PK P ++
Sbjct: 628 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTKGPTSTTSDKPA 685
Query: 2216 PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSS 2275
P + +P T P AP E P + E S S D+S+
Sbjct: 686 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS--EVSTPTTTKEPTTIHKSPDEST 743
Query: 2276 WDNQQENPPPTKKIGKK----PVAKMPLR-RPKM------KKTPEKLDNTPASPPRSPAE 2324
+ E P + K P K P +P+M K T L TP + +P
Sbjct: 744 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK- 802
Query: 2325 PNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTS 2384
+ K T T T++ + + Q + DT + KT+
Sbjct: 803 -----MTKETATTT------------EKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 845
Query: 2385 SKTP--SSPSKSPASFEIPASAMEANGVDGDGLN------KPAKKKKTPLKTDTFRVKKS 2436
+ P ++ K+ + EI E N KP K K P K + K
Sbjct: 846 TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS---TKK 902
Query: 2437 PKRSPLSDPPSQDPTPAATPETPPVIS 2463
PK P P PTP T P ++
Sbjct: 903 PKTMPRVRKPKTTPTPRKMTSTMPELN 929
Score = 68.9 bits (167), Expect = 7e-11
Identities = 174/870 (20%), Positives = 267/870 (30%), Gaps = 117/870 (13%)
Query: 1365 DAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEK---PVL 1421
D + ET ++ + E + + K+ T+ TS++ T + + I K K P
Sbjct: 135 DTSKETSLTVNK--ETTVETKETTTTNKQTSTDGKEKTTSAKE-TQSIEKTSAKDLAPTS 191
Query: 1422 GALATPGEKAGAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPA--RLQVEKKQQLA 1479
LA P KA + G LT P P P P P K+
Sbjct: 192 KVLAKPTPKAET--TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 249
Query: 1480 GEAEISHLALQDPASDKLLGPAGLTWERNLPGAGVGKEMAGVP----PTLREDERPEGPG 1535
+ + ++PA PA T + P KE A PT ++ P P
Sbjct: 250 TTTKSAPTTPKEPAPTTTKEPAPTTPKE--PAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 307
Query: 1536 AAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVER-----AAAFQVAPHSHGEEAVA 1590
P + + P+P + P A + AP + E A
Sbjct: 308 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 367
Query: 1591 QDRIPSGKQHQETSACDSPHGEDGPGDFAHTGVPGHVPRST-CAPSPQREVLTVPEANSE 1649
+ P+ +E S A T P +T AP+ +E P E
Sbjct: 368 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE--PSPTTTKE 425
Query: 1650 PW-TLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGE--VADTPLEPGKVAG--AAGE 1704
P T P A A PAP T + TP EP A
Sbjct: 426 PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 485
Query: 1705 AEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAAL 1764
+T +T E A + + P T + + P + ++PA
Sbjct: 486 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA-------------- 531
Query: 1765 HGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPR 1824
P P+ A P+ P P + ++P EP T + P+ +P
Sbjct: 532 ----PTTPKAAAPNT-PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT-----APT 581
Query: 1825 PGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADLESPTLAASSY 1884
P+ PKK AP+ + T+ E + +P P P + +PT
Sbjct: 582 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE-PAPTTPKEPA 640
Query: 1885 HGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEASTPSCPDPAKDLS 1944
G T L PA P A ++P+ G S P K+ +
Sbjct: 641 PTTPKGTAPTTLK----EPAPT---TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 693
Query: 1945 RSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPR 2004
++ E A TP+ P P PPP + P + +P T + P
Sbjct: 694 PTTPKEPAPTTPKKPAPTT--PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPT 751
Query: 2005 SDSVEGSPFRP---PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTF---QTLEPRASD 2058
++E SP P + + +A E A T D T T E +
Sbjct: 752 PKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT 811
Query: 2059 AKNQEGKVN------TRRKSTDSVP-----ISKSTLSRSLSLQASDFDGASSSGNPEAVA 2107
K E K+ T + D+ P + +TL+ ++ PE A
Sbjct: 812 EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 871
Query: 2108 LAPDAYSTGSSSASSTLKRTKKPRPPSLKKK----------------------------- 2138
D + ++ K TK P+ P+ KK
Sbjct: 872 KPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 931
Query: 2139 --------QTTKKPTETPPVKETQQEPDEE 2160
QTT +P +TP K + P E
Sbjct: 932 SRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 961
Score = 68.2 bits (165), Expect = 1e-10
Identities = 126/605 (20%), Positives = 192/605 (31%), Gaps = 101/605 (16%)
Query: 2031 ASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPIS-------KSTL 2083
A SG N DF + DT T Q KV+T K T + PI+ S
Sbjct: 88 AGSGLDNGDF-KVTTPDTSTT----------QHNKVSTSPKITTAKPINPRPSLPPNSDT 136
Query: 2084 SRSLSL-----------QASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP 2132
S+ SL + + + +S+ E A + S +SA +K
Sbjct: 137 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 196
Query: 2133 PSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETP 2192
P+ K + TTK P T P + T P E + E + K+ + P+P + P
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256
Query: 2193 LEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVT---PSD 2249
PK P ++ P + P K+ P TT E T P+
Sbjct: 257 ----TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP-TTPKEPAPTTPKKPAP 311
Query: 2250 SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 2309
+ +E +P + K + P PT K K P K P
Sbjct: 312 TTPKEPAP------------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP- 358
Query: 2310 KLDNTPASP-PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYN 2368
TP P P +P EP P ++ +PK P +
Sbjct: 359 ---TTPKEPAPTTPKEP----------------------APTTTKEPSPTTPKEPAPTTT 393
Query: 2369 FDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKT 2428
T + P T S + SP + + PA K P T
Sbjct: 394 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 453
Query: 2429 DTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTV-- 2486
+ + P P ++P P ET P + T EKLA T + T
Sbjct: 454 TPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 512
Query: 2487 DLEADKQDYPQPSDLSTFVNET-KFSSPTEELDYRNSYEIEYMEKIGSSLPQD--DDAPK 2543
+L + P P+ T K ++P ++ + P++ PK
Sbjct: 513 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP------------KEPAPTTPKEPAPTTPK 560
Query: 2544 KQALYLMFDTSQESPVKSSPVRMSE-------SPTPCSGSSFEETEALVNTAAKNQHPVP 2596
+ A +T+ +P ++P + E P P + E T K P
Sbjct: 561 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 620
Query: 2597 RGLAP 2601
+G AP
Sbjct: 621 KGTAP 625
Score = 57.0 bits (136), Expect = 3e-07
Identities = 106/514 (20%), Positives = 169/514 (32%), Gaps = 67/514 (13%)
Query: 2136 KKKQTTKKPTETPPVKETQQEPDEESLVPSGENLAS--ETKTESAKTEGPSPALLEETPL 2193
KK +T KKPT PPV + + S + +G+ + +T T SP + P
Sbjct: 70 KKNRTKKKPTPKPPVVD-----EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP- 123
Query: 2194 EPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQ 2253
+ P+ + P +S++++ + S V ++ T E E T ++
Sbjct: 124 ---INPRPSLPPNSDTSK------------ETSLTVNKE-----TTVETKETTTTNKQTS 163
Query: 2254 EDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPV--AKMPLRRPKMKKTPEKL 2311
D K S + E +S ++ PT K+ KP A+ + P + E
Sbjct: 164 TDGKEKTTSAK------ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT 217
Query: 2312 DNTPASP-PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFD 2370
TP P +P EP I T P ++T +PK P + +
Sbjct: 218 PTTPKEPASTTPKEPTPTTIKSAPTT--------PKEPAPTTTKSAPTTPKEPAPTTTKE 269
Query: 2371 P-DTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTD 2429
P T + P T P++ +P + + PA P + T K
Sbjct: 270 PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP----TTPKEPAPTTPKEP 325
Query: 2430 TFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLE 2489
T K P P +++P P E P T ++ A T K T E
Sbjct: 326 TPTTPKEPA------PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 379
Query: 2490 AD--KQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQAL 2547
P P+ + TK +PT + + P P
Sbjct: 380 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 439
Query: 2548 YLMFDTSQESPVKSSPVRMSESPTPCSGSSFEET---EALVNTAAKNQHPVPRGLAPNQE 2604
T+ + P ++P + P P + T E T + P+ L P
Sbjct: 440 KKPAPTTPKEPAPTTP----KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 495
Query: 2605 SHL--QVPEKSSQKELEAMGLGTPSEAIEITAPE 2636
L PEK + E + TP E T E
Sbjct: 496 EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 529
Score = 53.1 bits (126), Expect = 4e-06
Identities = 122/631 (19%), Positives = 194/631 (30%), Gaps = 82/631 (12%)
Query: 137 SPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAV----PSAGRERQPKEEGQKSSFSFSS 192
+PR PN+ + ++++ +E + G+E+ + + S +S
Sbjct: 125 NPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK-ETQSIEKTS 183
Query: 193 GIDQSPGMS----PVPLREPM-KAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQ 247
D +P P P E K P +P + KE A P + + S
Sbjct: 184 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT--PTTPKEPASTTPKEPTPTTIKSAP 241
Query: 248 VTPEAPAAAQQGTESSAVLEKSPL-----KPMAPIPQDPAPRASDRERGQGEAPPQYLTD 302
TP+ PA T+S+ K P +P P++PAP +
Sbjct: 242 TTPKEPAPTT--TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP------------- 286
Query: 303 DLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGS 362
P + A + A + P P P P+P E +
Sbjct: 287 ---------APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPTTPKEPAPT 336
Query: 363 GKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSL 422
KE T + P T P + A P+ P +P+ T T+E P +
Sbjct: 337 TKEPAPTTPKEPAP------TAPKK----PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 386
Query: 423 ASFPAA--QIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGE 480
P P +EP ++ +S S KE + +
Sbjct: 387 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT------TPKEPAPTTPK 440
Query: 481 HPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQS------------HEVQP 528
P + PAP+ + T++ P P P PKE + ++ P
Sbjct: 441 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP 500
Query: 529 GAPPPPLPKAPSESA-RGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPD 587
P P P P E A P PT T+P A + KE AP P
Sbjct: 501 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 560
Query: 588 GGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGP 647
+P +++ + K L +P+ + P + ++ + D P
Sbjct: 561 --EPAPTTPKETAPTTPK---GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 615
Query: 648 HSQTAEADASGLPHKLGEEDP--VLPPVPDGAGEPTVPEGAIWEGSGLQPK--CPDTLQS 703
T + A P + P P P G T+ E A PK P T +
Sbjct: 616 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 675
Query: 704 REGLGRMESFLTLESEKSDFPPTPVAEVAPK 734
+ T E + P A PK
Sbjct: 676 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPK 706
Score = 48.5 bits (114), Expect = 1e-04
Identities = 132/700 (18%), Positives = 207/700 (29%), Gaps = 153/700 (21%)
Query: 266 LEKSPLKPMAPIPQ---DPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPE 322
+EK+ K +AP + P P+A +G P+ T P+ + P+
Sbjct: 179 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT--------PKEPASTTPK 230
Query: 323 AEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQTGMRG 382
+P + A P+P A + KE T + P T
Sbjct: 231 ------------EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 278
Query: 383 T-----KPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEP 437
+P +A P+ P +P+ T +E P + P P +EP
Sbjct: 279 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT-----PKEPTPTTPKEP 333
Query: 438 GSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQER 497
+++E P + PAP+ ++
Sbjct: 334 APTTKE--------------------------------------PAPTTPKEPAPTAPKK 355
Query: 498 GEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHE 557
++ P P P KE S P AP+ + P T A
Sbjct: 356 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 415
Query: 558 DSTSPAVAKE-GSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELS 616
SP KE +P + + P P +P ++ ++K+ E +
Sbjct: 416 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 475
Query: 617 KPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDG 676
+ + P + P K + P T E A P E P P P
Sbjct: 476 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE---EPTPTTPEEP-- 530
Query: 677 AGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQ 736
PT P+ A P+T + E T E + PT E AP
Sbjct: 531 --APTTPKAA----------APNTPKEPAPTTPKEPAPTTPKEPA---PTTPKETAPTTP 575
Query: 737 EGESTLEIRKMG------SCDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLAAD 790
+G + +++ E T+ +P CD P P+G
Sbjct: 576 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP-------APTTPKGT----- 623
Query: 791 LGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQ 850
P+ P E P ++ K +P+ P+ + LKE A
Sbjct: 624 --------------APTTPKE----------PAPTTPK--EPAPTTPKGTAPTTLKEPA- 656
Query: 851 PPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTL 910
T+P P K+ +++ P D PT E PK
Sbjct: 657 ------PTTPKKPAPKELAPTTTK--GPTSTTSDKPAPT-------TPKETAPTTPKEPA 701
Query: 911 SDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRPE 950
TP P E+ SE+S PT K P K P+
Sbjct: 702 PTTP-KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 740
Score = 37.4 bits (85), Expect = 0.22
Identities = 84/379 (22%), Positives = 116/379 (30%), Gaps = 42/379 (11%)
Query: 1040 TGEAPPCQPDSVALLDAVPCLPA-LAPASPG-VTPTQDAPETEACDETQEGRQQPVPAPQ 1097
T E P P A P PA P P TP + AP T ++ PAP
Sbjct: 337 TKEPAPTTPKEPA--PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE---PAPT 391
Query: 1098 QKMECWATSDAESPKLLASFPSAGEQGGEAGAAE---TGGSAGAGDPGKQQAPEKPGEAT 1154
T+ +P S P+ ++ E T A K+ AP P E
Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 451
Query: 1155 LSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDALLPARELGGIPRSTMDFSTHQ 1214
+ T E A T+ + + P P+ T + +
Sbjct: 452 PT----------TPKEPAPTTTKKPA------------PTTPKEPAPTTPKETAPTTPKK 489
Query: 1215 AVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGA----EDSGVKAVSSADPRAPGESPCP 1270
P E L PE AP TP + + E+ +A P P E
Sbjct: 490 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 549
Query: 1271 VGEPPLALENAASLKLFAGSLAPLLQPGAAGGEI--PA-VQASSGSPK--ARTTEGPVDS 1325
+ P AP G A + PA +PK A TT S
Sbjct: 550 TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS 609
Query: 1326 MPCLDRMPLLAKGKQ-ATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDP 1384
C P KG T +E A T P A + +G A E + + P +
Sbjct: 610 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 669
Query: 1385 KQGTSGGVDTSSEQIATLT 1403
T G T+S++ A T
Sbjct: 670 PTTTKGPTSTTSDKPAPTT 688
Score = 32.0 bits (71), Expect = 9.3
Identities = 105/542 (19%), Positives = 166/542 (30%), Gaps = 43/542 (7%)
Query: 831 QPSQAQPETSIFDVLKEQAQ--PPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLP 888
+P+ P+ KE + P E T+ S P + A ++ P P+E +
Sbjct: 363 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 422
Query: 889 THGGQEQALGSELQSQLPKGTLSDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKR 948
T E PK TP E + T E APT K PA +
Sbjct: 423 T---------KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE-PAPTTTKKPAPTTPK 472
Query: 949 PEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQH- 1007
+++ +P LA K P ++ EE +
Sbjct: 473 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA------PTTPEELAPTTPEEPTPTT 526
Query: 1008 -EEACQRHPGASEAADGCSPLWGLSKREMASGNTGEAPPCQPDSVALLDAVPCLPALAPA 1066
EE P A+ P + +E A E P P A P
Sbjct: 527 PEEPAPTTPKAAAPNTPKEPA-PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 585
Query: 1067 SPGVTPTQDAPETEACDETQEGRQQPV--PAPQQKMECWATSDAESPKLLASFPSAGEQG 1124
TP + AP+ A T+E PAP T+ E P+
Sbjct: 586 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP- 644
Query: 1125 GEAGAAETGGSAGAGDPGKQQAPEKPGEATLSCGLLQTEH--CLTSGEEASTSALRESCQ 1182
G A T A K+ AP++ T T T+ +E + + +E
Sbjct: 645 --KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 702
Query: 1183 A--EHPMASCQDALLPARELGGIPRSTMDFSTHQAVPDPKELLLSGPPEVAA-------P 1233
+ P + + P P +T + +T PD LS P A P
Sbjct: 703 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 762
Query: 1234 DTPYLHVDSAAQ----RGAEDSGVKAVSSADPRAPGESPCPVGEPPLALENAASLKLFAG 1289
P +A + A+D + P +P E E K+ A
Sbjct: 763 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 822
Query: 1290 S--LAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATGEEKA 1347
+ + +I ++ ++ +PK TT+ + + +++ AK K KA
Sbjct: 823 TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 882
Query: 1348 AT 1349
T
Sbjct: 883 TT 884
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 89.0 bits (219), Expect = 6e-17
Identities = 192/885 (21%), Positives = 301/885 (34%), Gaps = 93/885 (10%)
Query: 1771 RPQQAKEQPGPERPI--PAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPS 1828
+ + K++P P+ P+ AG G +T + ++ T + P PS
Sbjct: 111 KKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 170
Query: 1829 MLP-SVPKKDAPRVMDKVTSDETR---------GAEGTESSPVADDI--IQPAAPADLE- 1875
+ P S K+ ++K T+ ET+ +G E + A + I+ + DL
Sbjct: 171 LPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP 230
Query: 1876 -SPTLAASSYHGDVVGQVSTDLIAQSISPAAAH--AGLPPSAAEHIVSPSAPAGDRVEA- 1931
S LA + + + + +P A P SAP + A
Sbjct: 231 TSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 290
Query: 1932 -STPSCPDPAKDLSRSSDSEEAFETPESTTPV----------KAPPAPPPPPPEVIPEPE 1980
+T S P K+ + ++ E A TP+ P K+ P P P P+
Sbjct: 291 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 350
Query: 1981 VSTQPPPEEPGCGSETVPV-PDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLD 2039
T P P E P P P + E +P P + +A KP ++
Sbjct: 351 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA---PKKPAPTTPKEPAP 407
Query: 2040 FDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASS 2099
E T T EP + K +T P +T S + + ++
Sbjct: 408 TTPKEPAPT-TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS---PTT 463
Query: 2100 SGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDE 2159
+ P A +T A +T K P P TTKKP T P + P E
Sbjct: 464 TKEPAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPAPTTTKKPAPTTPKEPAPTTPKE 522
Query: 2160 ------ESLVPSG-ENLASETKTESAKT--EGPSPALLEE----TPLEPA-VGPKAACPL 2205
+ L P+ E LA T + A T E +P EE TP EPA PKAA P
Sbjct: 523 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN 582
Query: 2206 DSESAEGVVP----PASGGGRVQNSPPVGRKTLPLTTAP----EAGEVTPSDSGGQEDSP 2257
+ P P + +P T P TAP E TP +E +P
Sbjct: 583 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 642
Query: 2258 AKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPAS 2317
+ + + DK + + P T K K P P L +
Sbjct: 643 T---TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 699
Query: 2318 PPRSPAEPNDIPIA-KGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDE 2376
P+ PA P KG + DK + T+ + +P P++ P+T
Sbjct: 700 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 759
Query: 2377 SVDPFKT--SSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPA-KKKKTPLKTDTFRV 2433
+ T ++K P++ KSP SA + +P KTP T
Sbjct: 760 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT 819
Query: 2434 KKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKL-AVTNQKWTCMTVDLEADK 2492
+ ++ D + T A P+ + T E K+ A T Q + T D K
Sbjct: 820 TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFK 879
Query: 2493 QDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFD 2552
+ + L+ V TK + T E+ M K P++ PK +A +
Sbjct: 880 ITTLKTTTLAPKVTTTKKTITTTEI----------MNK-----PEETAKPKDRAT----N 920
Query: 2553 TSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPR 2597
+ +P P + + PT S ++ + + P PR
Sbjct: 921 SKATTPKPQKPTKAPKKPT-----STKKPKTMPRVRKPKTTPTPR 960
Score = 77.8 bits (190), Expect = 1e-13
Identities = 155/732 (21%), Positives = 241/732 (32%), Gaps = 70/732 (9%)
Query: 1628 PRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGE 1687
P +T P+P P EP T P A + A PAP T +
Sbjct: 305 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 364
Query: 1688 VADTPLEPGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQ 1747
TP P + A E +T + A + P T + + P + +
Sbjct: 365 -EPTPTTPKEPAPTTKEPAP----TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTK 419
Query: 1748 DPACS---DKAPGMEGTAALHGDSPARPQQAKEQPG-PERPIPAGDGKVCVSSPPEPDET 1803
+P+ + + AP +A PA P K P P+ P P + ++P EP T
Sbjct: 420 EPSPTTPKEPAPTTTKSAPTTTKEPA-PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 478
Query: 1804 HDPKLQHLAPEE-LHTDRESPRPGPSM--LPSVPKKDAPRVMDKVTSDETRGAEGTESSP 1860
K P+E T + P P + P+ PK+ AP T ET + +P
Sbjct: 479 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP-----TTPKETAPTTPKKLTP 533
Query: 1861 VADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHI-V 1919
+ + P P E P + T + +P A P + E
Sbjct: 534 TTPEKLAPTTP---EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 590
Query: 1920 SPSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEP 1979
+P PA + P+ P + + + P TTP K PAP P EP
Sbjct: 591 TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK--PAPKELAPTTTKEP 648
Query: 1980 EVST--QPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYN 2037
+T +P P P + T P P + E +P P + E P
Sbjct: 649 TSTTCDKPAPTTPKGTAPTTPKEPAPTTPK-EPAP-TTPKGTAPTTLKEPAPTTPKKPAP 706
Query: 2038 LDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDG 2096
+ T + + +E T ++ + P + T + S+
Sbjct: 707 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 766
Query: 2097 ASSSGNPEAVALAPDAYSTGSSSASSTLKRTK-KPRPPSLKKKQTTKKPTETPPVKETQQ 2155
+++ P + +PD ST SA T K + P+ P + TTK P T P T
Sbjct: 767 PTTTKEPTTIHKSPDE-STPELSAEPTPKALENSPKEPGV---PTTKTPAATKPEMTTTA 822
Query: 2156 EPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP 2215
++ ET T + K + E+T +ES
Sbjct: 823 ---KDKTTERDLRTTPETTTAAPKMTKETATTTEKT---------------TESKITATT 864
Query: 2216 PASGGGRVQNSPPVGRKTLPLTT-APEA----GEVTPSDSGGQEDSPAKGLSVRLEFDYS 2270
Q++ P TL TT AP+ +T ++ + + AK +
Sbjct: 865 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT 924
Query: 2271 EDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNT-PASPPRS-------- 2321
K + P + KKP +R+PK TP K+ +T P P S
Sbjct: 925 TPKPQKPTKAPKKPTST---KKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 981
Query: 2322 -PAEPNDIPIAK 2332
PN P +K
Sbjct: 982 TTTRPNQTPNSK 993
Score = 77.0 bits (188), Expect = 3e-13
Identities = 130/630 (20%), Positives = 201/630 (31%), Gaps = 65/630 (10%)
Query: 19 PRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSASLDPCLVSPEVT 78
P S P + + TP P S + T ++ A P +P T
Sbjct: 265 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 324
Query: 79 EPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSP 138
K+P P P + P+ + P P +P E P T+ P
Sbjct: 325 ---KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 381
Query: 139 R----REPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGI 194
+EPAP AP A P E +TP + P+ +E P + + + S
Sbjct: 382 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKE---PAPTTTKEPSPTTPKEPAPTTTKSAP 438
Query: 195 DQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPA 254
+ +P + P +P ++E PA + TP+ PA
Sbjct: 439 TTTKEPAPTTTKSAPTTP-----KEPSPTTTKEPAPTTPKEPAPTTP-KKPAPTTPKEPA 492
Query: 255 AAQQGTESSAVLEK-SPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTDDLEFLRACHLP 313
+ +K +P P P P P A + P+ L A P
Sbjct: 493 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 552
Query: 314 RSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPE-AGGSGKEALDTIDV 372
+ PE +E A P+ P+P E A + KE T
Sbjct: 553 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE---PAPTTPKEPAPTTPKEPAPTTPK 609
Query: 373 QGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPI 432
+ P T +GT P + +P P P P L PT P S+ PA P
Sbjct: 610 ETAPTT-PKGTAPTTL------KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP- 661
Query: 433 AVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHP----EGDPGE 488
+ + K P + ++ + KG P E P
Sbjct: 662 ------KGTAPTTPKEPAPTT---------------PKEPAPTTPKGTAPTTLKEPAPTT 700
Query: 489 VPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPG 548
P+P+E T+ P P PKE + P P P PK P+ + P
Sbjct: 701 PKKPAPKELAP-TTTKGPTSTTSDKPAPTTPKETA-PTTPKEPAPTTPKKPAPTTPETPP 758
Query: 549 PTDGAKVHEDSTSPAVAKEGS---RSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSK 605
PT + ++P KE + +SP +S P P + G + +
Sbjct: 759 PTT-----SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 813
Query: 606 RDPEVGKDELSKPSSDAESRDHPSSHSAQP 635
PE+ K +++ + R P + +A P
Sbjct: 814 TKPEMTTTAKDK-TTERDLRTTPETTTAAP 842
Score = 74.7 bits (182), Expect = 1e-12
Identities = 160/747 (21%), Positives = 249/747 (33%), Gaps = 94/747 (12%)
Query: 1781 PERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESP-----RPGPSML----P 1831
P+ P P + ++P EP T E T +S P P+ P
Sbjct: 254 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 313
Query: 1832 SVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPA-------APADLESPTLAASSY 1884
+ PK+ AP + T+ A T P +PA AP + PT
Sbjct: 314 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 373
Query: 1885 HGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHI-VSPSAPAGDRVEASTPSCP-DPAKD 1942
+ + + +P A P + E +P PA + +P+ P +PA
Sbjct: 374 PAPTTKEPAPTTPKEP-APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 432
Query: 1943 LSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVST--QPPPEEPGCGSETVP-- 1998
++S+ + + P TT AP P P P EP +T +P P P + T P
Sbjct: 433 TTKSAPTTT--KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 490
Query: 1999 -VPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS 2057
P P+ + + P+ K A + L E + T + +
Sbjct: 491 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP--TTPEKPA 548
Query: 2058 DAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTG 2116
+E T + T + P + T ++ + ++ P A +T
Sbjct: 549 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 608
Query: 2117 SSSASSTLKRT-----KKPRPPSLKKKQ-------TTKKPTETPPVKETQQEPDEESLVP 2164
+A +T K T K+P P + KK TTK+PT T K P +
Sbjct: 609 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 668
Query: 2165 SGENLASETKTESAKT-EGPSPALLEE----TPLEPAVGPKAACPLDSESAEGVVP---- 2215
E + K + T +G +P L+E TP +PA PK P ++
Sbjct: 669 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTKGPTSTTSDKPA 726
Query: 2216 PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSS 2275
P + +P T P AP E P + E S S D+S+
Sbjct: 727 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS--EVSTPTTTKEPTTIHKSPDEST 784
Query: 2276 WDNQQENPPPTKKIGKK----PVAKMPLR-RPKM------KKTPEKLDNTPASPPRSPAE 2324
+ E P + K P K P +P+M K T L TP + +P
Sbjct: 785 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK- 843
Query: 2325 PNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTS 2384
+ K T T T++ + + Q + DT + KT+
Sbjct: 844 -----MTKETATTT------------EKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 886
Query: 2385 SKTP--SSPSKSPASFEIPASAMEANGVDGDGLN------KPAKKKKTPLKTDTFRVKKS 2436
+ P ++ K+ + EI E N KP K K P K + K
Sbjct: 887 TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS---TKK 943
Query: 2437 PKRSPLSDPPSQDPTPAATPETPPVIS 2463
PK P P PTP T P ++
Sbjct: 944 PKTMPRVRKPKTTPTPRKMTSTMPELN 970
Score = 68.9 bits (167), Expect = 7e-11
Identities = 174/870 (20%), Positives = 267/870 (30%), Gaps = 117/870 (13%)
Query: 1365 DAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEK---PVL 1421
D + ET ++ + E + + K+ T+ TS++ T + + I K K P
Sbjct: 176 DTSKETSLTVNK--ETTVETKETTTTNKQTSTDGKEKTTSAKE-TQSIEKTSAKDLAPTS 232
Query: 1422 GALATPGEKAGAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPA--RLQVEKKQQLA 1479
LA P KA + G LT P P P P P K+
Sbjct: 233 KVLAKPTPKAET--TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 290
Query: 1480 GEAEISHLALQDPASDKLLGPAGLTWERNLPGAGVGKEMAGVP----PTLREDERPEGPG 1535
+ + ++PA PA T + P KE A PT ++ P P
Sbjct: 291 TTTKSAPTTPKEPAPTTTKEPAPTTPKE--PAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 348
Query: 1536 AAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVER-----AAAFQVAPHSHGEEAVA 1590
P + + P+P + P A + AP + E A
Sbjct: 349 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 408
Query: 1591 QDRIPSGKQHQETSACDSPHGEDGPGDFAHTGVPGHVPRST-CAPSPQREVLTVPEANSE 1649
+ P+ +E S A T P +T AP+ +E P E
Sbjct: 409 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE--PSPTTTKE 466
Query: 1650 PW-TLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGE--VADTPLEPGKVAG--AAGE 1704
P T P A A PAP T + TP EP A
Sbjct: 467 PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 526
Query: 1705 AEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAAL 1764
+T +T E A + + P T + + P + ++PA
Sbjct: 527 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA-------------- 572
Query: 1765 HGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPR 1824
P P+ A P+ P P + ++P EP T + P+ +P
Sbjct: 573 ----PTTPKAAAPNT-PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT-----APT 622
Query: 1825 PGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADLESPTLAASSY 1884
P+ PKK AP+ + T+ E + +P P P + +PT
Sbjct: 623 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE-PAPTTPKEPA 681
Query: 1885 HGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEASTPSCPDPAKDLS 1944
G T L PA P A ++P+ G S P K+ +
Sbjct: 682 PTTPKGTAPTTLK----EPAPT---TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 734
Query: 1945 RSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPR 2004
++ E A TP+ P P PPP + P + +P T + P
Sbjct: 735 PTTPKEPAPTTPKKPAPTT--PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPT 792
Query: 2005 SDSVEGSPFRP---PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTF---QTLEPRASD 2058
++E SP P + + +A E A T D T T E +
Sbjct: 793 PKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT 852
Query: 2059 AKNQEGKVN------TRRKSTDSVP-----ISKSTLSRSLSLQASDFDGASSSGNPEAVA 2107
K E K+ T + D+ P + +TL+ ++ PE A
Sbjct: 853 EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 912
Query: 2108 LAPDAYSTGSSSASSTLKRTKKPRPPSLKKK----------------------------- 2138
D + ++ K TK P+ P+ KK
Sbjct: 913 KPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 972
Query: 2139 --------QTTKKPTETPPVKETQQEPDEE 2160
QTT +P +TP K + P E
Sbjct: 973 SRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 1002
Score = 68.2 bits (165), Expect = 1e-10
Identities = 126/605 (20%), Positives = 192/605 (31%), Gaps = 101/605 (16%)
Query: 2031 ASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPIS-------KSTL 2083
A SG N DF + DT T Q KV+T K T + PI+ S
Sbjct: 129 AGSGLDNGDF-KVTTPDTSTT----------QHNKVSTSPKITTAKPINPRPSLPPNSDT 177
Query: 2084 SRSLSL-----------QASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP 2132
S+ SL + + + +S+ E A + S +SA +K
Sbjct: 178 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 237
Query: 2133 PSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETP 2192
P+ K + TTK P T P + T P E + E + K+ + P+P + P
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297
Query: 2193 LEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVT---PSD 2249
PK P ++ P + P K+ P TT E T P+
Sbjct: 298 ----TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP-TTPKEPAPTTPKKPAP 352
Query: 2250 SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 2309
+ +E +P + K + P PT K K P K P
Sbjct: 353 TTPKEPAP------------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP- 399
Query: 2310 KLDNTPASP-PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYN 2368
TP P P +P EP P ++ +PK P +
Sbjct: 400 ---TTPKEPAPTTPKEP----------------------APTTTKEPSPTTPKEPAPTTT 434
Query: 2369 FDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKT 2428
T + P T S + SP + + PA K P T
Sbjct: 435 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 494
Query: 2429 DTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTV-- 2486
+ + P P ++P P ET P + T EKLA T + T
Sbjct: 495 TPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 553
Query: 2487 DLEADKQDYPQPSDLSTFVNET-KFSSPTEELDYRNSYEIEYMEKIGSSLPQD--DDAPK 2543
+L + P P+ T K ++P ++ + P++ PK
Sbjct: 554 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP------------KEPAPTTPKEPAPTTPK 601
Query: 2544 KQALYLMFDTSQESPVKSSPVRMSE-------SPTPCSGSSFEETEALVNTAAKNQHPVP 2596
+ A +T+ +P ++P + E P P + E T K P
Sbjct: 602 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 661
Query: 2597 RGLAP 2601
+G AP
Sbjct: 662 KGTAP 666
Score = 57.0 bits (136), Expect = 3e-07
Identities = 106/514 (20%), Positives = 169/514 (32%), Gaps = 67/514 (13%)
Query: 2136 KKKQTTKKPTETPPVKETQQEPDEESLVPSGENLAS--ETKTESAKTEGPSPALLEETPL 2193
KK +T KKPT PPV + + S + +G+ + +T T SP + P
Sbjct: 111 KKNRTKKKPTPKPPVVD-----EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP- 164
Query: 2194 EPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQ 2253
+ P+ + P +S++++ + S V ++ T E E T ++
Sbjct: 165 ---INPRPSLPPNSDTSK------------ETSLTVNKE-----TTVETKETTTTNKQTS 204
Query: 2254 EDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPV--AKMPLRRPKMKKTPEKL 2311
D K S + E +S ++ PT K+ KP A+ + P + E
Sbjct: 205 TDGKEKTTSAK------ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT 258
Query: 2312 DNTPASP-PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFD 2370
TP P +P EP I T P ++T +PK P + +
Sbjct: 259 PTTPKEPASTTPKEPTPTTIKSAPTT--------PKEPAPTTTKSAPTTPKEPAPTTTKE 310
Query: 2371 P-DTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTD 2429
P T + P T P++ +P + + PA P + T K
Sbjct: 311 PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP----TTPKEPAPTTPKEP 366
Query: 2430 TFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLE 2489
T K P P +++P P E P T ++ A T K T E
Sbjct: 367 TPTTPKEPA------PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 420
Query: 2490 AD--KQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQAL 2547
P P+ + TK +PT + + P P
Sbjct: 421 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 480
Query: 2548 YLMFDTSQESPVKSSPVRMSESPTPCSGSSFEET---EALVNTAAKNQHPVPRGLAPNQE 2604
T+ + P ++P + P P + T E T + P+ L P
Sbjct: 481 KKPAPTTPKEPAPTTP----KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 536
Query: 2605 SHL--QVPEKSSQKELEAMGLGTPSEAIEITAPE 2636
L PEK + E + TP E T E
Sbjct: 537 EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 570
Score = 53.1 bits (126), Expect = 4e-06
Identities = 122/631 (19%), Positives = 194/631 (30%), Gaps = 82/631 (12%)
Query: 137 SPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAV----PSAGRERQPKEEGQKSSFSFSS 192
+PR PN+ + ++++ +E + G+E+ + + S +S
Sbjct: 166 NPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK-ETQSIEKTS 224
Query: 193 GIDQSPGMS----PVPLREPM-KAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQ 247
D +P P P E K P +P + KE A P + + S
Sbjct: 225 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT--PTTPKEPASTTPKEPTPTTIKSAP 282
Query: 248 VTPEAPAAAQQGTESSAVLEKSPL-----KPMAPIPQDPAPRASDRERGQGEAPPQYLTD 302
TP+ PA T+S+ K P +P P++PAP +
Sbjct: 283 TTPKEPAPTT--TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP------------- 327
Query: 303 DLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGS 362
P + A + A + P P P P+P E +
Sbjct: 328 ---------APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPTTPKEPAPT 377
Query: 363 GKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSL 422
KE T + P T P + A P+ P +P+ T T+E P +
Sbjct: 378 TKEPAPTTPKEPAP------TAPKK----PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 427
Query: 423 ASFPAA--QIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGE 480
P P +EP ++ +S S KE + +
Sbjct: 428 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT------TPKEPAPTTPK 481
Query: 481 HPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQS------------HEVQP 528
P + PAP+ + T++ P P P PKE + ++ P
Sbjct: 482 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP 541
Query: 529 GAPPPPLPKAPSESA-RGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPD 587
P P P P E A P PT T+P A + KE AP P
Sbjct: 542 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 601
Query: 588 GGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGP 647
+P +++ + K L +P+ + P + ++ + D P
Sbjct: 602 --EPAPTTPKETAPTTPK---GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 656
Query: 648 HSQTAEADASGLPHKLGEEDP--VLPPVPDGAGEPTVPEGAIWEGSGLQPK--CPDTLQS 703
T + A P + P P P G T+ E A PK P T +
Sbjct: 657 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 716
Query: 704 REGLGRMESFLTLESEKSDFPPTPVAEVAPK 734
+ T E + P A PK
Sbjct: 717 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPK 747
Score = 48.5 bits (114), Expect = 1e-04
Identities = 132/700 (18%), Positives = 207/700 (29%), Gaps = 153/700 (21%)
Query: 266 LEKSPLKPMAPIPQ---DPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPE 322
+EK+ K +AP + P P+A +G P+ T P+ + P+
Sbjct: 220 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT--------PKEPASTTPK 271
Query: 323 AEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQTGMRG 382
+P + A P+P A + KE T + P T
Sbjct: 272 ------------EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 319
Query: 383 T-----KPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEP 437
+P +A P+ P +P+ T +E P + P P +EP
Sbjct: 320 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT-----PKEPTPTTPKEP 374
Query: 438 GSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQER 497
+++E P + PAP+ ++
Sbjct: 375 APTTKE--------------------------------------PAPTTPKEPAPTAPKK 396
Query: 498 GEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHE 557
++ P P P KE S P AP+ + P T A
Sbjct: 397 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 456
Query: 558 DSTSPAVAKE-GSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELS 616
SP KE +P + + P P +P ++ ++K+ E +
Sbjct: 457 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 516
Query: 617 KPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDG 676
+ + P + P K + P T E A P E P P P
Sbjct: 517 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE---EPTPTTPEEP-- 571
Query: 677 AGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQ 736
PT P+ A P+T + E T E + PT E AP
Sbjct: 572 --APTTPKAA----------APNTPKEPAPTTPKEPAPTTPKEPA---PTTPKETAPTTP 616
Query: 737 EGESTLEIRKMG------SCDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLAAD 790
+G + +++ E T+ +P CD P P+G
Sbjct: 617 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP-------APTTPKGT----- 664
Query: 791 LGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQ 850
P+ P E P ++ K +P+ P+ + LKE A
Sbjct: 665 --------------APTTPKE----------PAPTTPK--EPAPTTPKGTAPTTLKEPA- 697
Query: 851 PPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTL 910
T+P P K+ +++ P D PT E PK
Sbjct: 698 ------PTTPKKPAPKELAPTTTK--GPTSTTSDKPAPT-------TPKETAPTTPKEPA 742
Query: 911 SDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRPE 950
TP P E+ SE+S PT K P K P+
Sbjct: 743 PTTP-KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 781
Score = 37.4 bits (85), Expect = 0.22
Identities = 84/379 (22%), Positives = 116/379 (30%), Gaps = 42/379 (11%)
Query: 1040 TGEAPPCQPDSVALLDAVPCLPA-LAPASPG-VTPTQDAPETEACDETQEGRQQPVPAPQ 1097
T E P P A P PA P P TP + AP T ++ PAP
Sbjct: 378 TKEPAPTTPKEPA--PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE---PAPT 432
Query: 1098 QKMECWATSDAESPKLLASFPSAGEQGGEAGAAE---TGGSAGAGDPGKQQAPEKPGEAT 1154
T+ +P S P+ ++ E T A K+ AP P E
Sbjct: 433 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 492
Query: 1155 LSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDALLPARELGGIPRSTMDFSTHQ 1214
+ T E A T+ + + P P+ T + +
Sbjct: 493 PT----------TPKEPAPTTTKKPA------------PTTPKEPAPTTPKETAPTTPKK 530
Query: 1215 AVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGA----EDSGVKAVSSADPRAPGESPCP 1270
P E L PE AP TP + + E+ +A P P E
Sbjct: 531 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 590
Query: 1271 VGEPPLALENAASLKLFAGSLAPLLQPGAAGGEI--PA-VQASSGSPK--ARTTEGPVDS 1325
+ P AP G A + PA +PK A TT S
Sbjct: 591 TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS 650
Query: 1326 MPCLDRMPLLAKGKQ-ATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDP 1384
C P KG T +E A T P A + +G A E + + P +
Sbjct: 651 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 710
Query: 1385 KQGTSGGVDTSSEQIATLT 1403
T G T+S++ A T
Sbjct: 711 PTTTKGPTSTTSDKPAPTT 729
Score = 32.0 bits (71), Expect = 9.3
Identities = 105/542 (19%), Positives = 166/542 (30%), Gaps = 43/542 (7%)
Query: 831 QPSQAQPETSIFDVLKEQAQ--PPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLP 888
+P+ P+ KE + P E T+ S P + A ++ P P+E +
Sbjct: 404 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 463
Query: 889 THGGQEQALGSELQSQLPKGTLSDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKR 948
T E PK TP E + T E APT K PA +
Sbjct: 464 T---------KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE-PAPTTTKKPAPTTPK 513
Query: 949 PEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQH- 1007
+++ +P LA K P ++ EE +
Sbjct: 514 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA------PTTPEELAPTTPEEPTPTT 567
Query: 1008 -EEACQRHPGASEAADGCSPLWGLSKREMASGNTGEAPPCQPDSVALLDAVPCLPALAPA 1066
EE P A+ P + +E A E P P A P
Sbjct: 568 PEEPAPTTPKAAAPNTPKEPA-PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 626
Query: 1067 SPGVTPTQDAPETEACDETQEGRQQPV--PAPQQKMECWATSDAESPKLLASFPSAGEQG 1124
TP + AP+ A T+E PAP T+ E P+
Sbjct: 627 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP- 685
Query: 1125 GEAGAAETGGSAGAGDPGKQQAPEKPGEATLSCGLLQTEH--CLTSGEEASTSALRESCQ 1182
G A T A K+ AP++ T T T+ +E + + +E
Sbjct: 686 --KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 743
Query: 1183 A--EHPMASCQDALLPARELGGIPRSTMDFSTHQAVPDPKELLLSGPPEVAA-------P 1233
+ P + + P P +T + +T PD LS P A P
Sbjct: 744 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 803
Query: 1234 DTPYLHVDSAAQ----RGAEDSGVKAVSSADPRAPGESPCPVGEPPLALENAASLKLFAG 1289
P +A + A+D + P +P E E K+ A
Sbjct: 804 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 863
Query: 1290 S--LAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATGEEKA 1347
+ + +I ++ ++ +PK TT+ + + +++ AK K KA
Sbjct: 864 TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 923
Query: 1348 AT 1349
T
Sbjct: 924 TT 925
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 89.0 bits (219), Expect = 6e-17
Identities = 192/885 (21%), Positives = 301/885 (34%), Gaps = 93/885 (10%)
Query: 1771 RPQQAKEQPGPERPI--PAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPS 1828
+ + K++P P+ P+ AG G +T + ++ T + P PS
Sbjct: 163 KKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 222
Query: 1829 MLP-SVPKKDAPRVMDKVTSDETR---------GAEGTESSPVADDI--IQPAAPADLE- 1875
+ P S K+ ++K T+ ET+ +G E + A + I+ + DL
Sbjct: 223 LPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP 282
Query: 1876 -SPTLAASSYHGDVVGQVSTDLIAQSISPAAAH--AGLPPSAAEHIVSPSAPAGDRVEA- 1931
S LA + + + + +P A P SAP + A
Sbjct: 283 TSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 342
Query: 1932 -STPSCPDPAKDLSRSSDSEEAFETPESTTPV----------KAPPAPPPPPPEVIPEPE 1980
+T S P K+ + ++ E A TP+ P K+ P P P P+
Sbjct: 343 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 402
Query: 1981 VSTQPPPEEPGCGSETVPV-PDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLD 2039
T P P E P P P + E +P P + +A KP ++
Sbjct: 403 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA---PKKPAPTTPKEPAP 459
Query: 2040 FDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASS 2099
E T T EP + K +T P +T S + + ++
Sbjct: 460 TTPKEPAPT-TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS---PTT 515
Query: 2100 SGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDE 2159
+ P A +T A +T K P P TTKKP T P + P E
Sbjct: 516 TKEPAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPAPTTTKKPAPTTPKEPAPTTPKE 574
Query: 2160 ------ESLVPSG-ENLASETKTESAKT--EGPSPALLEE----TPLEPA-VGPKAACPL 2205
+ L P+ E LA T + A T E +P EE TP EPA PKAA P
Sbjct: 575 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN 634
Query: 2206 DSESAEGVVP----PASGGGRVQNSPPVGRKTLPLTTAP----EAGEVTPSDSGGQEDSP 2257
+ P P + +P T P TAP E TP +E +P
Sbjct: 635 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 694
Query: 2258 AKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPAS 2317
+ + + DK + + P T K K P P L +
Sbjct: 695 T---TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 751
Query: 2318 PPRSPAEPNDIPIA-KGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDE 2376
P+ PA P KG + DK + T+ + +P P++ P+T
Sbjct: 752 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 811
Query: 2377 SVDPFKT--SSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPA-KKKKTPLKTDTFRV 2433
+ T ++K P++ KSP SA + +P KTP T
Sbjct: 812 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT 871
Query: 2434 KKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKL-AVTNQKWTCMTVDLEADK 2492
+ ++ D + T A P+ + T E K+ A T Q + T D K
Sbjct: 872 TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFK 931
Query: 2493 QDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFD 2552
+ + L+ V TK + T E+ M K P++ PK +A +
Sbjct: 932 ITTLKTTTLAPKVTTTKKTITTTEI----------MNK-----PEETAKPKDRAT----N 972
Query: 2553 TSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPR 2597
+ +P P + + PT S ++ + + P PR
Sbjct: 973 SKATTPKPQKPTKAPKKPT-----STKKPKTMPRVRKPKTTPTPR 1012
Score = 77.8 bits (190), Expect = 1e-13
Identities = 155/732 (21%), Positives = 241/732 (32%), Gaps = 70/732 (9%)
Query: 1628 PRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGE 1687
P +T P+P P EP T P A + A PAP T +
Sbjct: 357 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 416
Query: 1688 VADTPLEPGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQ 1747
TP P + A E +T + A + P T + + P + +
Sbjct: 417 -EPTPTTPKEPAPTTKEPAP----TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTK 471
Query: 1748 DPACS---DKAPGMEGTAALHGDSPARPQQAKEQPG-PERPIPAGDGKVCVSSPPEPDET 1803
+P+ + + AP +A PA P K P P+ P P + ++P EP T
Sbjct: 472 EPSPTTPKEPAPTTTKSAPTTTKEPA-PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 530
Query: 1804 HDPKLQHLAPEE-LHTDRESPRPGPSM--LPSVPKKDAPRVMDKVTSDETRGAEGTESSP 1860
K P+E T + P P + P+ PK+ AP T ET + +P
Sbjct: 531 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP-----TTPKETAPTTPKKLTP 585
Query: 1861 VADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHI-V 1919
+ + P P E P + T + +P A P + E
Sbjct: 586 TTPEKLAPTTP---EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 642
Query: 1920 SPSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEP 1979
+P PA + P+ P + + + P TTP K PAP P EP
Sbjct: 643 TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK--PAPKELAPTTTKEP 700
Query: 1980 EVST--QPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYN 2037
+T +P P P + T P P + E +P P + E P
Sbjct: 701 TSTTCDKPAPTTPKGTAPTTPKEPAPTTPK-EPAP-TTPKGTAPTTLKEPAPTTPKKPAP 758
Query: 2038 LDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDG 2096
+ T + + +E T ++ + P + T + S+
Sbjct: 759 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 818
Query: 2097 ASSSGNPEAVALAPDAYSTGSSSASSTLKRTK-KPRPPSLKKKQTTKKPTETPPVKETQQ 2155
+++ P + +PD ST SA T K + P+ P + TTK P T P T
Sbjct: 819 PTTTKEPTTIHKSPDE-STPELSAEPTPKALENSPKEPGV---PTTKTPAATKPEMTTTA 874
Query: 2156 EPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP 2215
++ ET T + K + E+T +ES
Sbjct: 875 ---KDKTTERDLRTTPETTTAAPKMTKETATTTEKT---------------TESKITATT 916
Query: 2216 PASGGGRVQNSPPVGRKTLPLTT-APEA----GEVTPSDSGGQEDSPAKGLSVRLEFDYS 2270
Q++ P TL TT AP+ +T ++ + + AK +
Sbjct: 917 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT 976
Query: 2271 EDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNT-PASPPRS-------- 2321
K + P + KKP +R+PK TP K+ +T P P S
Sbjct: 977 TPKPQKPTKAPKKPTST---KKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 1033
Query: 2322 -PAEPNDIPIAK 2332
PN P +K
Sbjct: 1034 TTTRPNQTPNSK 1045
Score = 77.0 bits (188), Expect = 3e-13
Identities = 130/630 (20%), Positives = 201/630 (31%), Gaps = 65/630 (10%)
Query: 19 PRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSASLDPCLVSPEVT 78
P S P + + TP P S + T ++ A P +P T
Sbjct: 317 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 376
Query: 79 EPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSP 138
K+P P P + P+ + P P +P E P T+ P
Sbjct: 377 ---KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 433
Query: 139 R----REPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGI 194
+EPAP AP A P E +TP + P+ +E P + + + S
Sbjct: 434 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKE---PAPTTTKEPSPTTPKEPAPTTTKSAP 490
Query: 195 DQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPA 254
+ +P + P +P ++E PA + TP+ PA
Sbjct: 491 TTTKEPAPTTTKSAPTTP-----KEPSPTTTKEPAPTTPKEPAPTTP-KKPAPTTPKEPA 544
Query: 255 AAQQGTESSAVLEK-SPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTDDLEFLRACHLP 313
+ +K +P P P P P A + P+ L A P
Sbjct: 545 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 604
Query: 314 RSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPE-AGGSGKEALDTIDV 372
+ PE +E A P+ P+P E A + KE T
Sbjct: 605 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE---PAPTTPKEPAPTTPKEPAPTTPK 661
Query: 373 QGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPI 432
+ P T +GT P + +P P P P L PT P S+ PA P
Sbjct: 662 ETAPTT-PKGTAPTTL------KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP- 713
Query: 433 AVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHP----EGDPGE 488
+ + K P + ++ + KG P E P
Sbjct: 714 ------KGTAPTTPKEPAPTT---------------PKEPAPTTPKGTAPTTLKEPAPTT 752
Query: 489 VPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPG 548
P+P+E T+ P P PKE + P P P PK P+ + P
Sbjct: 753 PKKPAPKELAP-TTTKGPTSTTSDKPAPTTPKETA-PTTPKEPAPTTPKKPAPTTPETPP 810
Query: 549 PTDGAKVHEDSTSPAVAKEGS---RSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSK 605
PT + ++P KE + +SP +S P P + G + +
Sbjct: 811 PTT-----SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 865
Query: 606 RDPEVGKDELSKPSSDAESRDHPSSHSAQP 635
PE+ K +++ + R P + +A P
Sbjct: 866 TKPEMTTTAKDK-TTERDLRTTPETTTAAP 894
Score = 74.7 bits (182), Expect = 1e-12
Identities = 160/747 (21%), Positives = 249/747 (33%), Gaps = 94/747 (12%)
Query: 1781 PERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESP-----RPGPSML----P 1831
P+ P P + ++P EP T E T +S P P+ P
Sbjct: 306 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 365
Query: 1832 SVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPA-------APADLESPTLAASSY 1884
+ PK+ AP + T+ A T P +PA AP + PT
Sbjct: 366 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 425
Query: 1885 HGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHI-VSPSAPAGDRVEASTPSCP-DPAKD 1942
+ + + +P A P + E +P PA + +P+ P +PA
Sbjct: 426 PAPTTKEPAPTTPKEP-APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 484
Query: 1943 LSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVST--QPPPEEPGCGSETVP-- 1998
++S+ + + P TT AP P P P EP +T +P P P + T P
Sbjct: 485 TTKSAPTTT--KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 542
Query: 1999 -VPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS 2057
P P+ + + P+ K A + L E + T + +
Sbjct: 543 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP--TTPEKPA 600
Query: 2058 DAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTG 2116
+E T + T + P + T ++ + ++ P A +T
Sbjct: 601 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 660
Query: 2117 SSSASSTLKRT-----KKPRPPSLKKKQ-------TTKKPTETPPVKETQQEPDEESLVP 2164
+A +T K T K+P P + KK TTK+PT T K P +
Sbjct: 661 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 720
Query: 2165 SGENLASETKTESAKT-EGPSPALLEE----TPLEPAVGPKAACPLDSESAEGVVP---- 2215
E + K + T +G +P L+E TP +PA PK P ++
Sbjct: 721 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTKGPTSTTSDKPA 778
Query: 2216 PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSS 2275
P + +P T P AP E P + E S S D+S+
Sbjct: 779 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS--EVSTPTTTKEPTTIHKSPDEST 836
Query: 2276 WDNQQENPPPTKKIGKK----PVAKMPLR-RPKM------KKTPEKLDNTPASPPRSPAE 2324
+ E P + K P K P +P+M K T L TP + +P
Sbjct: 837 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK- 895
Query: 2325 PNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTS 2384
+ K T T T++ + + Q + DT + KT+
Sbjct: 896 -----MTKETATTT------------EKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 938
Query: 2385 SKTP--SSPSKSPASFEIPASAMEANGVDGDGLN------KPAKKKKTPLKTDTFRVKKS 2436
+ P ++ K+ + EI E N KP K K P K + K
Sbjct: 939 TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS---TKK 995
Query: 2437 PKRSPLSDPPSQDPTPAATPETPPVIS 2463
PK P P PTP T P ++
Sbjct: 996 PKTMPRVRKPKTTPTPRKMTSTMPELN 1022
Score = 68.9 bits (167), Expect = 7e-11
Identities = 174/870 (20%), Positives = 267/870 (30%), Gaps = 117/870 (13%)
Query: 1365 DAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEK---PVL 1421
D + ET ++ + E + + K+ T+ TS++ T + + I K K P
Sbjct: 228 DTSKETSLTVNK--ETTVETKETTTTNKQTSTDGKEKTTSAKE-TQSIEKTSAKDLAPTS 284
Query: 1422 GALATPGEKAGAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPA--RLQVEKKQQLA 1479
LA P KA + G LT P P P P P K+
Sbjct: 285 KVLAKPTPKAET--TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 342
Query: 1480 GEAEISHLALQDPASDKLLGPAGLTWERNLPGAGVGKEMAGVP----PTLREDERPEGPG 1535
+ + ++PA PA T + P KE A PT ++ P P
Sbjct: 343 TTTKSAPTTPKEPAPTTTKEPAPTTPKE--PAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 400
Query: 1536 AAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVER-----AAAFQVAPHSHGEEAVA 1590
P + + P+P + P A + AP + E A
Sbjct: 401 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 460
Query: 1591 QDRIPSGKQHQETSACDSPHGEDGPGDFAHTGVPGHVPRST-CAPSPQREVLTVPEANSE 1649
+ P+ +E S A T P +T AP+ +E P E
Sbjct: 461 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE--PSPTTTKE 518
Query: 1650 PW-TLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGE--VADTPLEPGKVAG--AAGE 1704
P T P A A PAP T + TP EP A
Sbjct: 519 PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 578
Query: 1705 AEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAAL 1764
+T +T E A + + P T + + P + ++PA
Sbjct: 579 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA-------------- 624
Query: 1765 HGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPR 1824
P P+ A P+ P P + ++P EP T + P+ +P
Sbjct: 625 ----PTTPKAAAPNT-PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT-----APT 674
Query: 1825 PGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADLESPTLAASSY 1884
P+ PKK AP+ + T+ E + +P P P + +PT
Sbjct: 675 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE-PAPTTPKEPA 733
Query: 1885 HGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEASTPSCPDPAKDLS 1944
G T L PA P A ++P+ G S P K+ +
Sbjct: 734 PTTPKGTAPTTLK----EPAPT---TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 786
Query: 1945 RSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPR 2004
++ E A TP+ P P PPP + P + +P T + P
Sbjct: 787 PTTPKEPAPTTPKKPAPTT--PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPT 844
Query: 2005 SDSVEGSPFRP---PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTF---QTLEPRASD 2058
++E SP P + + +A E A T D T T E +
Sbjct: 845 PKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT 904
Query: 2059 AKNQEGKVN------TRRKSTDSVP-----ISKSTLSRSLSLQASDFDGASSSGNPEAVA 2107
K E K+ T + D+ P + +TL+ ++ PE A
Sbjct: 905 EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 964
Query: 2108 LAPDAYSTGSSSASSTLKRTKKPRPPSLKKK----------------------------- 2138
D + ++ K TK P+ P+ KK
Sbjct: 965 KPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 1024
Query: 2139 --------QTTKKPTETPPVKETQQEPDEE 2160
QTT +P +TP K + P E
Sbjct: 1025 SRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 1054
Score = 68.2 bits (165), Expect = 1e-10
Identities = 126/605 (20%), Positives = 192/605 (31%), Gaps = 101/605 (16%)
Query: 2031 ASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPIS-------KSTL 2083
A SG N DF + DT T Q KV+T K T + PI+ S
Sbjct: 181 AGSGLDNGDF-KVTTPDTSTT----------QHNKVSTSPKITTAKPINPRPSLPPNSDT 229
Query: 2084 SRSLSL-----------QASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP 2132
S+ SL + + + +S+ E A + S +SA +K
Sbjct: 230 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 289
Query: 2133 PSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETP 2192
P+ K + TTK P T P + T P E + E + K+ + P+P + P
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349
Query: 2193 LEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVT---PSD 2249
PK P ++ P + P K+ P TT E T P+
Sbjct: 350 ----TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP-TTPKEPAPTTPKKPAP 404
Query: 2250 SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 2309
+ +E +P + K + P PT K K P K P
Sbjct: 405 TTPKEPAP------------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP- 451
Query: 2310 KLDNTPASP-PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYN 2368
TP P P +P EP P ++ +PK P +
Sbjct: 452 ---TTPKEPAPTTPKEP----------------------APTTTKEPSPTTPKEPAPTTT 486
Query: 2369 FDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKT 2428
T + P T S + SP + + PA K P T
Sbjct: 487 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 546
Query: 2429 DTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTV-- 2486
+ + P P ++P P ET P + T EKLA T + T
Sbjct: 547 TPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 605
Query: 2487 DLEADKQDYPQPSDLSTFVNET-KFSSPTEELDYRNSYEIEYMEKIGSSLPQD--DDAPK 2543
+L + P P+ T K ++P ++ + P++ PK
Sbjct: 606 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP------------KEPAPTTPKEPAPTTPK 653
Query: 2544 KQALYLMFDTSQESPVKSSPVRMSE-------SPTPCSGSSFEETEALVNTAAKNQHPVP 2596
+ A +T+ +P ++P + E P P + E T K P
Sbjct: 654 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 713
Query: 2597 RGLAP 2601
+G AP
Sbjct: 714 KGTAP 718
Score = 63.5 bits (153), Expect = 3e-09
Identities = 125/613 (20%), Positives = 206/613 (33%), Gaps = 87/613 (14%)
Query: 2051 TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDF-DGASSSGNPEAVALA 2109
T P + A G T + +T P + +++ + + S S N E+ +
Sbjct: 70 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS-- 127
Query: 2110 PDAYSTGSSSASSTLKRTKKPRPPSL-------------KKKQTTKKPTETPPVKETQQE 2156
S+ SSS+SST+++ K + + KK +T KKPT PPV +
Sbjct: 128 ----SSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD---- 179
Query: 2157 PDEESLVPSGENLAS--ETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVV 2214
+ S + +G+ + +T T SP + P + P+ + P +S++++
Sbjct: 180 -EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP----INPRPSLPPNSDTSK--- 231
Query: 2215 PPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKS 2274
+ S V ++ T E E T ++ D K S + E +S
Sbjct: 232 ---------ETSLTVNKE-----TTVETKETTTTNKQTSTDGKEKTTSAK------ETQS 271
Query: 2275 SWDNQQENPPPTKKIGKKPV--AKMPLRRPKMKKTPEKLDNTPASP-PRSPAEPNDIPIA 2331
++ PT K+ KP A+ + P + E TP P +P EP I
Sbjct: 272 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 331
Query: 2332 KGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDP-DTCDESVDPFKTSSKTPSS 2390
T P ++T +PK P + +P T + P T P++
Sbjct: 332 SAPTT--------PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 383
Query: 2391 PSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDP 2450
+P + + PA P + T K T K P P +++P
Sbjct: 384 TKSAPTTPKEPAPTTPKKPAP----TTPKEPAPTTPKEPTPTTPKEPA------PTTKEP 433
Query: 2451 TPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEAD--KQDYPQPSDLSTFVNET 2508
P E P T ++ A T K T E P P+ + T
Sbjct: 434 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 493
Query: 2509 KFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSE 2568
K +PT + + P P T+ + P ++P +
Sbjct: 494 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP----K 549
Query: 2569 SPTPCSGSSFEET---EALVNTAAKNQHPVPRGLAPNQESHL--QVPEKSSQKELEAMGL 2623
P P + T E T + P+ L P L PEK + E +
Sbjct: 550 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 609
Query: 2624 GTPSEAIEITAPE 2636
TP E T E
Sbjct: 610 TTPEEPTPTTPEE 622
Score = 53.9 bits (128), Expect = 2e-06
Identities = 146/772 (18%), Positives = 237/772 (30%), Gaps = 99/772 (12%)
Query: 8 SDNQRTLSAQTPRSAQPPGN--------SQNIKRKQQDTPGSPDHRDASSIGSVGLGGFC 59
S +T+ + T RS +PP S+ I + + +SS S
Sbjct: 82 SGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKI 141
Query: 60 TASESSASLDPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPE 119
+S++SA+ +V + +K+ + P PP E + F P+
Sbjct: 142 KSSKNSAANRELQKKLKVKDNKKNRTKKKPT-----PKPPVVDEAGSGLDNGDFKVTTPD 196
Query: 120 GCLASPAAAPEDGPQTQS----PRREPAPNAPGDIAAAFPAERDSSTPYQEIAAV----P 171
T + PR PN+ + ++++ +E
Sbjct: 197 TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 256
Query: 172 SAGRERQPKEEGQKSSFSFSSGIDQSPGMS----PVPLREPM-KAPLCGEGDQPGGFESQ 226
+ G+E+ + + S +S D +P P P E K P +P +
Sbjct: 257 TDGKEKTTSAK-ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT--PTT 313
Query: 227 EKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPL-----KPMAPIPQDP 281
KE A P + + S TP+ PA T+S+ K P +P P++P
Sbjct: 314 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTT--TKSAPTTPKEPAPTTTKEPAPTTPKEP 371
Query: 282 APRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYL 341
AP + P + A + A + P
Sbjct: 372 APTTTKEP----------------------APTTTKSAPTTPKEPAPTTPKKPAPTTPKE 409
Query: 342 PHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGL 401
P P P+P E + KE T + P T P + A P+
Sbjct: 410 PAPTTP-KEPTPTTPKEPAPTTKEPAPTTPKEPAP------TAPKK----PAPTTPKEPA 458
Query: 402 PVSPEPSLLTPTEEAHPASSLASFPAA--QIPIAVEEPGSSSRESVSKAGMPVSADAAKE 459
P +P+ T T+E P + P P +EP ++ +S S KE
Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 518
Query: 460 VVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLP 519
+ + P + PAP+ + T++ P P P P
Sbjct: 519 PAPT------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 572
Query: 520 KEQS------------HEVQPGAPPPPLPKAPSESA-RGPPGPTDGAKVHEDSTSPAVAK 566
KE + ++ P P P P P E A P PT T+P A
Sbjct: 573 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 632
Query: 567 EGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRD 626
+ KE AP P +P +++ + K L +P+ +
Sbjct: 633 PNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPK---GTAPTTLKEPAPTTPKKP 687
Query: 627 HPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDP--VLPPVPDGAGEPTVPE 684
P + ++ + D P T + A P + P P P G T+ E
Sbjct: 688 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 747
Query: 685 GAIWEGSGLQPK--CPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPK 734
A PK P T + + T E + P A PK
Sbjct: 748 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK 799
Score = 48.5 bits (114), Expect = 1e-04
Identities = 132/700 (18%), Positives = 207/700 (29%), Gaps = 153/700 (21%)
Query: 266 LEKSPLKPMAPIPQ---DPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPE 322
+EK+ K +AP + P P+A +G P+ T P+ + P+
Sbjct: 272 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT--------PKEPASTTPK 323
Query: 323 AEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQTGMRG 382
+P + A P+P A + KE T + P T
Sbjct: 324 ------------EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 371
Query: 383 T-----KPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEP 437
+P +A P+ P +P+ T +E P + P P +EP
Sbjct: 372 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT-----PKEPTPTTPKEP 426
Query: 438 GSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQER 497
+++E P + PAP+ ++
Sbjct: 427 APTTKE--------------------------------------PAPTTPKEPAPTAPKK 448
Query: 498 GEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHE 557
++ P P P KE S P AP+ + P T A
Sbjct: 449 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 508
Query: 558 DSTSPAVAKE-GSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELS 616
SP KE +P + + P P +P ++ ++K+ E +
Sbjct: 509 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 568
Query: 617 KPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDG 676
+ + P + P K + P T E A P E P P P
Sbjct: 569 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE---EPTPTTPEEP-- 623
Query: 677 AGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQ 736
PT P+ A P+T + E T E + PT E AP
Sbjct: 624 --APTTPKAA----------APNTPKEPAPTTPKEPAPTTPKEPA---PTTPKETAPTTP 668
Query: 737 EGESTLEIRKMG------SCDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLAAD 790
+G + +++ E T+ +P CD P P+G
Sbjct: 669 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP-------APTTPKGT----- 716
Query: 791 LGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQ 850
P+ P E P ++ K +P+ P+ + LKE A
Sbjct: 717 --------------APTTPKE----------PAPTTPK--EPAPTTPKGTAPTTLKEPA- 749
Query: 851 PPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTL 910
T+P P K+ +++ P D PT E PK
Sbjct: 750 ------PTTPKKPAPKELAPTTTK--GPTSTTSDKPAPT-------TPKETAPTTPKEPA 794
Query: 911 SDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRPE 950
TP P E+ SE+S PT K P K P+
Sbjct: 795 PTTP-KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 833
Score = 37.4 bits (85), Expect = 0.22
Identities = 84/379 (22%), Positives = 116/379 (30%), Gaps = 42/379 (11%)
Query: 1040 TGEAPPCQPDSVALLDAVPCLPA-LAPASPG-VTPTQDAPETEACDETQEGRQQPVPAPQ 1097
T E P P A P PA P P TP + AP T ++ PAP
Sbjct: 430 TKEPAPTTPKEPA--PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE---PAPT 484
Query: 1098 QKMECWATSDAESPKLLASFPSAGEQGGEAGAAE---TGGSAGAGDPGKQQAPEKPGEAT 1154
T+ +P S P+ ++ E T A K+ AP P E
Sbjct: 485 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 544
Query: 1155 LSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDALLPARELGGIPRSTMDFSTHQ 1214
+ T E A T+ + + P P+ T + +
Sbjct: 545 PT----------TPKEPAPTTTKKPA------------PTTPKEPAPTTPKETAPTTPKK 582
Query: 1215 AVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGA----EDSGVKAVSSADPRAPGESPCP 1270
P E L PE AP TP + + E+ +A P P E
Sbjct: 583 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 642
Query: 1271 VGEPPLALENAASLKLFAGSLAPLLQPGAAGGEI--PA-VQASSGSPK--ARTTEGPVDS 1325
+ P AP G A + PA +PK A TT S
Sbjct: 643 TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS 702
Query: 1326 MPCLDRMPLLAKGKQ-ATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDP 1384
C P KG T +E A T P A + +G A E + + P +
Sbjct: 703 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 762
Query: 1385 KQGTSGGVDTSSEQIATLT 1403
T G T+S++ A T
Sbjct: 763 PTTTKGPTSTTSDKPAPTT 781
Score = 33.1 bits (74), Expect = 4.2
Identities = 179/964 (18%), Positives = 308/964 (31%), Gaps = 80/964 (8%)
Query: 415 EAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSD 474
E H +S S A P + + + + ++ P + K+V+++ + E VS+
Sbjct: 65 EVHNPTSPPSSKKAPPPSGASQ---TIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSE 121
Query: 475 LGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPP 534
E + + ++ N+ + E+Q + K ++ + +P PP
Sbjct: 122 ---NQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKK-KPTPKPPV 177
Query: 535 LPKAPSESARGP----PGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGD 590
+ +A S G T + ++ STSP + +P S + +
Sbjct: 178 VDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTV 237
Query: 591 PGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQ 650
E + ++ + E + + + +S + S+ P K A T P ++
Sbjct: 238 NKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT--PKAE 295
Query: 651 TAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPK--CPDTLQSREGLG 708
T + K E P P P + P P + + PK P T +S
Sbjct: 296 TTTKGPALTTPK--EPTPTTPKEP-ASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 352
Query: 709 RMESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPRGPACD 768
+ + T K P TP E AP + + + + E T+P +P
Sbjct: 353 KEPAPTTT---KEPAPTTP-KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP----AP 404
Query: 769 ASRQEFHAGVPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEK 828
+ +E P P T ++ P+ P E A + P ++ K
Sbjct: 405 TTPKEPAPTTPKEPTPTTPKEPAPTT-------KEPAPTTPKEP--APTAPKKPAPTTPK 455
Query: 829 HLQPSQAQPETSIFDVLKEQAQ--PPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNN 886
+P+ P+ KE + P E T+ S P + A ++ P P+E +
Sbjct: 456 --EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 513
Query: 887 LPTHGGQEQALGSELQSQLPKGTLSDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGE 946
T E PK TP E + T E APT K PA
Sbjct: 514 TTT---------KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE-PAPTTTKKPAPTT 563
Query: 947 KRPEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQ 1006
+ +++ +P LA K P ++ EE +
Sbjct: 564 PKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA------PTTPEELAPTTPEEPTP 617
Query: 1007 H--EEACQRHPGASEAADGCSPLWGLSKREMASGNTGEAPPCQPDSVALLDAVPCLPALA 1064
EE P A+ P + +E A E P P A P
Sbjct: 618 TTPEEPAPTTPKAAAPNTPKEPA-PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 676
Query: 1065 PASPGVTPTQDAPETEACDETQEGRQQPV--PAPQQKMECWATSDAESPKLLASFPSAGE 1122
TP + AP+ A T+E PAP T+ E P+
Sbjct: 677 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT 736
Query: 1123 QGGEAGAAETGGSAGAGDPGKQQAPEKPGEATLSCGLLQTEH--CLTSGEEASTSALRES 1180
G A T A K+ AP++ T T T+ +E + + +E
Sbjct: 737 P---KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 793
Query: 1181 CQA--EHPMASCQDALLPARELGGIPRSTMDFSTHQAVPDPKELLLSGPPEVAA------ 1232
+ P + + P P +T + +T PD LS P A
Sbjct: 794 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 853
Query: 1233 -PDTPYLHVDSAAQ----RGAEDSGVKAVSSADPRAPGESPCPVGEPPLALENAASLKLF 1287
P P +A + A+D + P +P E E K+
Sbjct: 854 EPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKIT 913
Query: 1288 AGS--LAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATGEE 1345
A + + +I ++ ++ +PK TT+ + + +++ AK K
Sbjct: 914 ATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS 973
Query: 1346 KAAT 1349
KA T
Sbjct: 974 KATT 977
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 89.0 bits (219), Expect = 6e-17
Identities = 192/885 (21%), Positives = 301/885 (34%), Gaps = 93/885 (10%)
Query: 1771 RPQQAKEQPGPERPI--PAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPS 1828
+ + K++P P+ P+ AG G +T + ++ T + P PS
Sbjct: 204 KKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 263
Query: 1829 MLP-SVPKKDAPRVMDKVTSDETR---------GAEGTESSPVADDI--IQPAAPADLE- 1875
+ P S K+ ++K T+ ET+ +G E + A + I+ + DL
Sbjct: 264 LPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP 323
Query: 1876 -SPTLAASSYHGDVVGQVSTDLIAQSISPAAAH--AGLPPSAAEHIVSPSAPAGDRVEA- 1931
S LA + + + + +P A P SAP + A
Sbjct: 324 TSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 383
Query: 1932 -STPSCPDPAKDLSRSSDSEEAFETPESTTPV----------KAPPAPPPPPPEVIPEPE 1980
+T S P K+ + ++ E A TP+ P K+ P P P P+
Sbjct: 384 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 443
Query: 1981 VSTQPPPEEPGCGSETVPV-PDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLD 2039
T P P E P P P + E +P P + +A KP ++
Sbjct: 444 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA---PKKPAPTTPKEPAP 500
Query: 2040 FDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASS 2099
E T T EP + K +T P +T S + + ++
Sbjct: 501 TTPKEPAPT-TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS---PTT 556
Query: 2100 SGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDE 2159
+ P A +T A +T K P P TTKKP T P + P E
Sbjct: 557 TKEPAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPAPTTTKKPAPTTPKEPAPTTPKE 615
Query: 2160 ------ESLVPSG-ENLASETKTESAKT--EGPSPALLEE----TPLEPA-VGPKAACPL 2205
+ L P+ E LA T + A T E +P EE TP EPA PKAA P
Sbjct: 616 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN 675
Query: 2206 DSESAEGVVP----PASGGGRVQNSPPVGRKTLPLTTAP----EAGEVTPSDSGGQEDSP 2257
+ P P + +P T P TAP E TP +E +P
Sbjct: 676 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 735
Query: 2258 AKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPAS 2317
+ + + DK + + P T K K P P L +
Sbjct: 736 T---TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 792
Query: 2318 PPRSPAEPNDIPIA-KGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDE 2376
P+ PA P KG + DK + T+ + +P P++ P+T
Sbjct: 793 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 852
Query: 2377 SVDPFKT--SSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPA-KKKKTPLKTDTFRV 2433
+ T ++K P++ KSP SA + +P KTP T
Sbjct: 853 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT 912
Query: 2434 KKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKL-AVTNQKWTCMTVDLEADK 2492
+ ++ D + T A P+ + T E K+ A T Q + T D K
Sbjct: 913 TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFK 972
Query: 2493 QDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFD 2552
+ + L+ V TK + T E+ M K P++ PK +A +
Sbjct: 973 ITTLKTTTLAPKVTTTKKTITTTEI----------MNK-----PEETAKPKDRAT----N 1013
Query: 2553 TSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPR 2597
+ +P P + + PT S ++ + + P PR
Sbjct: 1014 SKATTPKPQKPTKAPKKPT-----STKKPKTMPRVRKPKTTPTPR 1053
Score = 77.8 bits (190), Expect = 1e-13
Identities = 155/732 (21%), Positives = 241/732 (32%), Gaps = 70/732 (9%)
Query: 1628 PRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGE 1687
P +T P+P P EP T P A + A PAP T +
Sbjct: 398 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 457
Query: 1688 VADTPLEPGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQ 1747
TP P + A E +T + A + P T + + P + +
Sbjct: 458 -EPTPTTPKEPAPTTKEPAP----TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTK 512
Query: 1748 DPACS---DKAPGMEGTAALHGDSPARPQQAKEQPG-PERPIPAGDGKVCVSSPPEPDET 1803
+P+ + + AP +A PA P K P P+ P P + ++P EP T
Sbjct: 513 EPSPTTPKEPAPTTTKSAPTTTKEPA-PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 571
Query: 1804 HDPKLQHLAPEE-LHTDRESPRPGPSM--LPSVPKKDAPRVMDKVTSDETRGAEGTESSP 1860
K P+E T + P P + P+ PK+ AP T ET + +P
Sbjct: 572 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP-----TTPKETAPTTPKKLTP 626
Query: 1861 VADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHI-V 1919
+ + P P E P + T + +P A P + E
Sbjct: 627 TTPEKLAPTTP---EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 683
Query: 1920 SPSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEP 1979
+P PA + P+ P + + + P TTP K PAP P EP
Sbjct: 684 TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK--PAPKELAPTTTKEP 741
Query: 1980 EVST--QPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYN 2037
+T +P P P + T P P + E +P P + E P
Sbjct: 742 TSTTCDKPAPTTPKGTAPTTPKEPAPTTPK-EPAP-TTPKGTAPTTLKEPAPTTPKKPAP 799
Query: 2038 LDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDG 2096
+ T + + +E T ++ + P + T + S+
Sbjct: 800 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 859
Query: 2097 ASSSGNPEAVALAPDAYSTGSSSASSTLKRTK-KPRPPSLKKKQTTKKPTETPPVKETQQ 2155
+++ P + +PD ST SA T K + P+ P + TTK P T P T
Sbjct: 860 PTTTKEPTTIHKSPDE-STPELSAEPTPKALENSPKEPGV---PTTKTPAATKPEMTTTA 915
Query: 2156 EPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP 2215
++ ET T + K + E+T +ES
Sbjct: 916 ---KDKTTERDLRTTPETTTAAPKMTKETATTTEKT---------------TESKITATT 957
Query: 2216 PASGGGRVQNSPPVGRKTLPLTT-APEA----GEVTPSDSGGQEDSPAKGLSVRLEFDYS 2270
Q++ P TL TT AP+ +T ++ + + AK +
Sbjct: 958 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT 1017
Query: 2271 EDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNT-PASPPRS-------- 2321
K + P + KKP +R+PK TP K+ +T P P S
Sbjct: 1018 TPKPQKPTKAPKKPTST---KKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 1074
Query: 2322 -PAEPNDIPIAK 2332
PN P +K
Sbjct: 1075 TTTRPNQTPNSK 1086
Score = 77.0 bits (188), Expect = 3e-13
Identities = 130/630 (20%), Positives = 201/630 (31%), Gaps = 65/630 (10%)
Query: 19 PRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSASLDPCLVSPEVT 78
P S P + + TP P S + T ++ A P +P T
Sbjct: 358 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 417
Query: 79 EPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSP 138
K+P P P + P+ + P P +P E P T+ P
Sbjct: 418 ---KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 474
Query: 139 R----REPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGI 194
+EPAP AP A P E +TP + P+ +E P + + + S
Sbjct: 475 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKE---PAPTTTKEPSPTTPKEPAPTTTKSAP 531
Query: 195 DQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPA 254
+ +P + P +P ++E PA + TP+ PA
Sbjct: 532 TTTKEPAPTTTKSAPTTP-----KEPSPTTTKEPAPTTPKEPAPTTP-KKPAPTTPKEPA 585
Query: 255 AAQQGTESSAVLEK-SPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTDDLEFLRACHLP 313
+ +K +P P P P P A + P+ L A P
Sbjct: 586 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 645
Query: 314 RSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPE-AGGSGKEALDTIDV 372
+ PE +E A P+ P+P E A + KE T
Sbjct: 646 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE---PAPTTPKEPAPTTPKEPAPTTPK 702
Query: 373 QGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPI 432
+ P T +GT P + +P P P P L PT P S+ PA P
Sbjct: 703 ETAPTT-PKGTAPTTL------KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP- 754
Query: 433 AVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHP----EGDPGE 488
+ + K P + ++ + KG P E P
Sbjct: 755 ------KGTAPTTPKEPAPTT---------------PKEPAPTTPKGTAPTTLKEPAPTT 793
Query: 489 VPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPG 548
P+P+E T+ P P PKE + P P P PK P+ + P
Sbjct: 794 PKKPAPKELAP-TTTKGPTSTTSDKPAPTTPKETA-PTTPKEPAPTTPKKPAPTTPETPP 851
Query: 549 PTDGAKVHEDSTSPAVAKEGS---RSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSK 605
PT + ++P KE + +SP +S P P + G + +
Sbjct: 852 PTT-----SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 906
Query: 606 RDPEVGKDELSKPSSDAESRDHPSSHSAQP 635
PE+ K +++ + R P + +A P
Sbjct: 907 TKPEMTTTAKDK-TTERDLRTTPETTTAAP 935
Score = 74.7 bits (182), Expect = 1e-12
Identities = 160/747 (21%), Positives = 249/747 (33%), Gaps = 94/747 (12%)
Query: 1781 PERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESP-----RPGPSML----P 1831
P+ P P + ++P EP T E T +S P P+ P
Sbjct: 347 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 406
Query: 1832 SVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPA-------APADLESPTLAASSY 1884
+ PK+ AP + T+ A T P +PA AP + PT
Sbjct: 407 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 466
Query: 1885 HGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHI-VSPSAPAGDRVEASTPSCP-DPAKD 1942
+ + + +P A P + E +P PA + +P+ P +PA
Sbjct: 467 PAPTTKEPAPTTPKEP-APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 525
Query: 1943 LSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVST--QPPPEEPGCGSETVP-- 1998
++S+ + + P TT AP P P P EP +T +P P P + T P
Sbjct: 526 TTKSAPTTT--KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 583
Query: 1999 -VPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS 2057
P P+ + + P+ K A + L E + T + +
Sbjct: 584 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP--TTPEKPA 641
Query: 2058 DAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTG 2116
+E T + T + P + T ++ + ++ P A +T
Sbjct: 642 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 701
Query: 2117 SSSASSTLKRT-----KKPRPPSLKKKQ-------TTKKPTETPPVKETQQEPDEESLVP 2164
+A +T K T K+P P + KK TTK+PT T K P +
Sbjct: 702 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 761
Query: 2165 SGENLASETKTESAKT-EGPSPALLEE----TPLEPAVGPKAACPLDSESAEGVVP---- 2215
E + K + T +G +P L+E TP +PA PK P ++
Sbjct: 762 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTKGPTSTTSDKPA 819
Query: 2216 PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSS 2275
P + +P T P AP E P + E S S D+S+
Sbjct: 820 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS--EVSTPTTTKEPTTIHKSPDEST 877
Query: 2276 WDNQQENPPPTKKIGKK----PVAKMPLR-RPKM------KKTPEKLDNTPASPPRSPAE 2324
+ E P + K P K P +P+M K T L TP + +P
Sbjct: 878 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK- 936
Query: 2325 PNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTS 2384
+ K T T T++ + + Q + DT + KT+
Sbjct: 937 -----MTKETATTT------------EKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 979
Query: 2385 SKTP--SSPSKSPASFEIPASAMEANGVDGDGLN------KPAKKKKTPLKTDTFRVKKS 2436
+ P ++ K+ + EI E N KP K K P K + K
Sbjct: 980 TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS---TKK 1036
Query: 2437 PKRSPLSDPPSQDPTPAATPETPPVIS 2463
PK P P PTP T P ++
Sbjct: 1037 PKTMPRVRKPKTTPTPRKMTSTMPELN 1063
Score = 68.9 bits (167), Expect = 7e-11
Identities = 174/870 (20%), Positives = 267/870 (30%), Gaps = 117/870 (13%)
Query: 1365 DAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEK---PVL 1421
D + ET ++ + E + + K+ T+ TS++ T + + I K K P
Sbjct: 269 DTSKETSLTVNK--ETTVETKETTTTNKQTSTDGKEKTTSAKE-TQSIEKTSAKDLAPTS 325
Query: 1422 GALATPGEKAGAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPA--RLQVEKKQQLA 1479
LA P KA + G LT P P P P P K+
Sbjct: 326 KVLAKPTPKAET--TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 383
Query: 1480 GEAEISHLALQDPASDKLLGPAGLTWERNLPGAGVGKEMAGVP----PTLREDERPEGPG 1535
+ + ++PA PA T + P KE A PT ++ P P
Sbjct: 384 TTTKSAPTTPKEPAPTTTKEPAPTTPKE--PAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 441
Query: 1536 AAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVER-----AAAFQVAPHSHGEEAVA 1590
P + + P+P + P A + AP + E A
Sbjct: 442 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 501
Query: 1591 QDRIPSGKQHQETSACDSPHGEDGPGDFAHTGVPGHVPRST-CAPSPQREVLTVPEANSE 1649
+ P+ +E S A T P +T AP+ +E P E
Sbjct: 502 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE--PSPTTTKE 559
Query: 1650 PW-TLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGE--VADTPLEPGKVAG--AAGE 1704
P T P A A PAP T + TP EP A
Sbjct: 560 PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 619
Query: 1705 AEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAAL 1764
+T +T E A + + P T + + P + ++PA
Sbjct: 620 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA-------------- 665
Query: 1765 HGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPR 1824
P P+ A P+ P P + ++P EP T + P+ +P
Sbjct: 666 ----PTTPKAAAPNT-PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT-----APT 715
Query: 1825 PGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADLESPTLAASSY 1884
P+ PKK AP+ + T+ E + +P P P + +PT
Sbjct: 716 TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE-PAPTTPKEPA 774
Query: 1885 HGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEASTPSCPDPAKDLS 1944
G T L PA P A ++P+ G S P K+ +
Sbjct: 775 PTTPKGTAPTTLK----EPAPT---TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 827
Query: 1945 RSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPR 2004
++ E A TP+ P P PPP + P + +P T + P
Sbjct: 828 PTTPKEPAPTTPKKPAPTT--PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPT 885
Query: 2005 SDSVEGSPFRP---PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTF---QTLEPRASD 2058
++E SP P + + +A E A T D T T E +
Sbjct: 886 PKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT 945
Query: 2059 AKNQEGKVN------TRRKSTDSVP-----ISKSTLSRSLSLQASDFDGASSSGNPEAVA 2107
K E K+ T + D+ P + +TL+ ++ PE A
Sbjct: 946 EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 1005
Query: 2108 LAPDAYSTGSSSASSTLKRTKKPRPPSLKKK----------------------------- 2138
D + ++ K TK P+ P+ KK
Sbjct: 1006 KPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 1065
Query: 2139 --------QTTKKPTETPPVKETQQEPDEE 2160
QTT +P +TP K + P E
Sbjct: 1066 SRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 1095
Score = 68.2 bits (165), Expect = 1e-10
Identities = 126/605 (20%), Positives = 192/605 (31%), Gaps = 101/605 (16%)
Query: 2031 ASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPIS-------KSTL 2083
A SG N DF + DT T Q KV+T K T + PI+ S
Sbjct: 222 AGSGLDNGDF-KVTTPDTSTT----------QHNKVSTSPKITTAKPINPRPSLPPNSDT 270
Query: 2084 SRSLSL-----------QASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP 2132
S+ SL + + + +S+ E A + S +SA +K
Sbjct: 271 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 330
Query: 2133 PSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETP 2192
P+ K + TTK P T P + T P E + E + K+ + P+P + P
Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 390
Query: 2193 LEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVT---PSD 2249
PK P ++ P + P K+ P TT E T P+
Sbjct: 391 ----TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP-TTPKEPAPTTPKKPAP 445
Query: 2250 SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 2309
+ +E +P + K + P PT K K P K P
Sbjct: 446 TTPKEPAP------------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP- 492
Query: 2310 KLDNTPASP-PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYN 2368
TP P P +P EP P ++ +PK P +
Sbjct: 493 ---TTPKEPAPTTPKEP----------------------APTTTKEPSPTTPKEPAPTTT 527
Query: 2369 FDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKT 2428
T + P T S + SP + + PA K P T
Sbjct: 528 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 587
Query: 2429 DTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTV-- 2486
+ + P P ++P P ET P + T EKLA T + T
Sbjct: 588 TPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 646
Query: 2487 DLEADKQDYPQPSDLSTFVNET-KFSSPTEELDYRNSYEIEYMEKIGSSLPQD--DDAPK 2543
+L + P P+ T K ++P ++ + P++ PK
Sbjct: 647 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP------------KEPAPTTPKEPAPTTPK 694
Query: 2544 KQALYLMFDTSQESPVKSSPVRMSE-------SPTPCSGSSFEETEALVNTAAKNQHPVP 2596
+ A +T+ +P ++P + E P P + E T K P
Sbjct: 695 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 754
Query: 2597 RGLAP 2601
+G AP
Sbjct: 755 KGTAP 759
Score = 63.5 bits (153), Expect = 3e-09
Identities = 125/613 (20%), Positives = 206/613 (33%), Gaps = 87/613 (14%)
Query: 2051 TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDF-DGASSSGNPEAVALA 2109
T P + A G T + +T P + +++ + + S S N E+ +
Sbjct: 111 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS-- 168
Query: 2110 PDAYSTGSSSASSTLKRTKKPRPPSL-------------KKKQTTKKPTETPPVKETQQE 2156
S+ SSS+SST+++ K + + KK +T KKPT PPV +
Sbjct: 169 ----SSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD---- 220
Query: 2157 PDEESLVPSGENLAS--ETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVV 2214
+ S + +G+ + +T T SP + P + P+ + P +S++++
Sbjct: 221 -EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP----INPRPSLPPNSDTSK--- 272
Query: 2215 PPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKS 2274
+ S V ++ T E E T ++ D K S + E +S
Sbjct: 273 ---------ETSLTVNKE-----TTVETKETTTTNKQTSTDGKEKTTSAK------ETQS 312
Query: 2275 SWDNQQENPPPTKKIGKKPV--AKMPLRRPKMKKTPEKLDNTPASP-PRSPAEPNDIPIA 2331
++ PT K+ KP A+ + P + E TP P +P EP I
Sbjct: 313 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 372
Query: 2332 KGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDP-DTCDESVDPFKTSSKTPSS 2390
T P ++T +PK P + +P T + P T P++
Sbjct: 373 SAPTT--------PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 424
Query: 2391 PSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDP 2450
+P + + PA P + T K T K P P +++P
Sbjct: 425 TKSAPTTPKEPAPTTPKKPAP----TTPKEPAPTTPKEPTPTTPKEPA------PTTKEP 474
Query: 2451 TPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEAD--KQDYPQPSDLSTFVNET 2508
P E P T ++ A T K T E P P+ + T
Sbjct: 475 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 534
Query: 2509 KFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSE 2568
K +PT + + P P T+ + P ++P +
Sbjct: 535 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP----K 590
Query: 2569 SPTPCSGSSFEET---EALVNTAAKNQHPVPRGLAPNQESHL--QVPEKSSQKELEAMGL 2623
P P + T E T + P+ L P L PEK + E +
Sbjct: 591 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 650
Query: 2624 GTPSEAIEITAPE 2636
TP E T E
Sbjct: 651 TTPEEPTPTTPEE 663
Score = 53.9 bits (128), Expect = 2e-06
Identities = 146/772 (18%), Positives = 237/772 (30%), Gaps = 99/772 (12%)
Query: 8 SDNQRTLSAQTPRSAQPPGN--------SQNIKRKQQDTPGSPDHRDASSIGSVGLGGFC 59
S +T+ + T RS +PP S+ I + + +SS S
Sbjct: 123 SGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKI 182
Query: 60 TASESSASLDPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPE 119
+S++SA+ +V + +K+ + P PP E + F P+
Sbjct: 183 KSSKNSAANRELQKKLKVKDNKKNRTKKKPT-----PKPPVVDEAGSGLDNGDFKVTTPD 237
Query: 120 GCLASPAAAPEDGPQTQS----PRREPAPNAPGDIAAAFPAERDSSTPYQEIAAV----P 171
T + PR PN+ + ++++ +E
Sbjct: 238 TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 297
Query: 172 SAGRERQPKEEGQKSSFSFSSGIDQSPGMS----PVPLREPM-KAPLCGEGDQPGGFESQ 226
+ G+E+ + + S +S D +P P P E K P +P +
Sbjct: 298 TDGKEKTTSAK-ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT--PTT 354
Query: 227 EKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPL-----KPMAPIPQDP 281
KE A P + + S TP+ PA T+S+ K P +P P++P
Sbjct: 355 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTT--TKSAPTTPKEPAPTTTKEPAPTTPKEP 412
Query: 282 APRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYL 341
AP + P + A + A + P
Sbjct: 413 APTTTKEP----------------------APTTTKSAPTTPKEPAPTTPKKPAPTTPKE 450
Query: 342 PHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGL 401
P P P+P E + KE T + P T P + A P+
Sbjct: 451 PAPTTP-KEPTPTTPKEPAPTTKEPAPTTPKEPAP------TAPKK----PAPTTPKEPA 499
Query: 402 PVSPEPSLLTPTEEAHPASSLASFPAA--QIPIAVEEPGSSSRESVSKAGMPVSADAAKE 459
P +P+ T T+E P + P P +EP ++ +S S KE
Sbjct: 500 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 559
Query: 460 VVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLP 519
+ + P + PAP+ + T++ P P P P
Sbjct: 560 PAPT------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 613
Query: 520 KEQS------------HEVQPGAPPPPLPKAPSESA-RGPPGPTDGAKVHEDSTSPAVAK 566
KE + ++ P P P P P E A P PT T+P A
Sbjct: 614 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 673
Query: 567 EGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRD 626
+ KE AP P +P +++ + K L +P+ +
Sbjct: 674 PNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPK---GTAPTTLKEPAPTTPKKP 728
Query: 627 HPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDP--VLPPVPDGAGEPTVPE 684
P + ++ + D P T + A P + P P P G T+ E
Sbjct: 729 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 788
Query: 685 GAIWEGSGLQPK--CPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPK 734
A PK P T + + T E + P A PK
Sbjct: 789 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK 840
Score = 48.5 bits (114), Expect = 1e-04
Identities = 132/700 (18%), Positives = 207/700 (29%), Gaps = 153/700 (21%)
Query: 266 LEKSPLKPMAPIPQ---DPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPE 322
+EK+ K +AP + P P+A +G P+ T P+ + P+
Sbjct: 313 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT--------PKEPASTTPK 364
Query: 323 AEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQTGMRG 382
+P + A P+P A + KE T + P T
Sbjct: 365 ------------EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 412
Query: 383 T-----KPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEP 437
+P +A P+ P +P+ T +E P + P P +EP
Sbjct: 413 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT-----PKEPTPTTPKEP 467
Query: 438 GSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQER 497
+++E P + PAP+ ++
Sbjct: 468 APTTKE--------------------------------------PAPTTPKEPAPTAPKK 489
Query: 498 GEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHE 557
++ P P P KE S P AP+ + P T A
Sbjct: 490 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 549
Query: 558 DSTSPAVAKE-GSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELS 616
SP KE +P + + P P +P ++ ++K+ E +
Sbjct: 550 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 609
Query: 617 KPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDG 676
+ + P + P K + P T E A P E P P P
Sbjct: 610 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE---EPTPTTPEEP-- 664
Query: 677 AGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQ 736
PT P+ A P+T + E T E + PT E AP
Sbjct: 665 --APTTPKAA----------APNTPKEPAPTTPKEPAPTTPKEPA---PTTPKETAPTTP 709
Query: 737 EGESTLEIRKMG------SCDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLAAD 790
+G + +++ E T+ +P CD P P+G
Sbjct: 710 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP-------APTTPKGT----- 757
Query: 791 LGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQ 850
P+ P E P ++ K +P+ P+ + LKE A
Sbjct: 758 --------------APTTPKE----------PAPTTPK--EPAPTTPKGTAPTTLKEPA- 790
Query: 851 PPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTL 910
T+P P K+ +++ P D PT E PK
Sbjct: 791 ------PTTPKKPAPKELAPTTTK--GPTSTTSDKPAPT-------TPKETAPTTPKEPA 835
Query: 911 SDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRPE 950
TP P E+ SE+S PT K P K P+
Sbjct: 836 PTTP-KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 874
Score = 37.4 bits (85), Expect = 0.22
Identities = 84/379 (22%), Positives = 116/379 (30%), Gaps = 42/379 (11%)
Query: 1040 TGEAPPCQPDSVALLDAVPCLPA-LAPASPG-VTPTQDAPETEACDETQEGRQQPVPAPQ 1097
T E P P A P PA P P TP + AP T ++ PAP
Sbjct: 471 TKEPAPTTPKEPA--PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE---PAPT 525
Query: 1098 QKMECWATSDAESPKLLASFPSAGEQGGEAGAAE---TGGSAGAGDPGKQQAPEKPGEAT 1154
T+ +P S P+ ++ E T A K+ AP P E
Sbjct: 526 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 585
Query: 1155 LSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDALLPARELGGIPRSTMDFSTHQ 1214
+ T E A T+ + + P P+ T + +
Sbjct: 586 PT----------TPKEPAPTTTKKPA------------PTTPKEPAPTTPKETAPTTPKK 623
Query: 1215 AVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGA----EDSGVKAVSSADPRAPGESPCP 1270
P E L PE AP TP + + E+ +A P P E
Sbjct: 624 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 683
Query: 1271 VGEPPLALENAASLKLFAGSLAPLLQPGAAGGEI--PA-VQASSGSPK--ARTTEGPVDS 1325
+ P AP G A + PA +PK A TT S
Sbjct: 684 TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS 743
Query: 1326 MPCLDRMPLLAKGKQ-ATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDP 1384
C P KG T +E A T P A + +G A E + + P +
Sbjct: 744 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 803
Query: 1385 KQGTSGGVDTSSEQIATLT 1403
T G T+S++ A T
Sbjct: 804 PTTTKGPTSTTSDKPAPTT 822
Score = 33.1 bits (74), Expect = 4.2
Identities = 179/964 (18%), Positives = 308/964 (31%), Gaps = 80/964 (8%)
Query: 415 EAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSD 474
E H +S S A P + + + + ++ P + K+V+++ + E VS+
Sbjct: 106 EVHNPTSPPSSKKAPPPSGASQ---TIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSE 162
Query: 475 LGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPP 534
E + + ++ N+ + E+Q + K ++ + +P PP
Sbjct: 163 ---NQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKK-KPTPKPPV 218
Query: 535 LPKAPSESARGP----PGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGD 590
+ +A S G T + ++ STSP + +P S + +
Sbjct: 219 VDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTV 278
Query: 591 PGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQ 650
E + ++ + E + + + +S + S+ P K A T P ++
Sbjct: 279 NKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT--PKAE 336
Query: 651 TAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPK--CPDTLQSREGLG 708
T + K E P P P + P P + + PK P T +S
Sbjct: 337 TTTKGPALTTPK--EPTPTTPKEP-ASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 393
Query: 709 RMESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPRGPACD 768
+ + T K P TP E AP + + + + E T+P +P
Sbjct: 394 KEPAPTTT---KEPAPTTP-KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP----AP 445
Query: 769 ASRQEFHAGVPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEK 828
+ +E P P T ++ P+ P E A + P ++ K
Sbjct: 446 TTPKEPAPTTPKEPTPTTPKEPAPTT-------KEPAPTTPKEP--APTAPKKPAPTTPK 496
Query: 829 HLQPSQAQPETSIFDVLKEQAQ--PPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNN 886
+P+ P+ KE + P E T+ S P + A ++ P P+E +
Sbjct: 497 --EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 554
Query: 887 LPTHGGQEQALGSELQSQLPKGTLSDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGE 946
T E PK TP E + T E APT K PA
Sbjct: 555 TTT---------KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE-PAPTTTKKPAPTT 604
Query: 947 KRPEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQ 1006
+ +++ +P LA K P ++ EE +
Sbjct: 605 PKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA------PTTPEELAPTTPEEPTP 658
Query: 1007 H--EEACQRHPGASEAADGCSPLWGLSKREMASGNTGEAPPCQPDSVALLDAVPCLPALA 1064
EE P A+ P + +E A E P P A P
Sbjct: 659 TTPEEPAPTTPKAAAPNTPKEPA-PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 717
Query: 1065 PASPGVTPTQDAPETEACDETQEGRQQPV--PAPQQKMECWATSDAESPKLLASFPSAGE 1122
TP + AP+ A T+E PAP T+ E P+
Sbjct: 718 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT 777
Query: 1123 QGGEAGAAETGGSAGAGDPGKQQAPEKPGEATLSCGLLQTEH--CLTSGEEASTSALRES 1180
G A T A K+ AP++ T T T+ +E + + +E
Sbjct: 778 P---KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 834
Query: 1181 CQA--EHPMASCQDALLPARELGGIPRSTMDFSTHQAVPDPKELLLSGPPEVAA------ 1232
+ P + + P P +T + +T PD LS P A
Sbjct: 835 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 894
Query: 1233 -PDTPYLHVDSAAQ----RGAEDSGVKAVSSADPRAPGESPCPVGEPPLALENAASLKLF 1287
P P +A + A+D + P +P E E K+
Sbjct: 895 EPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKIT 954
Query: 1288 AGS--LAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATGEE 1345
A + + +I ++ ++ +PK TT+ + + +++ AK K
Sbjct: 955 ATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS 1014
Query: 1346 KAAT 1349
KA T
Sbjct: 1015 KATT 1018
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 88.6 bits (218), Expect = 8e-17
Identities = 282/1341 (21%), Positives = 441/1341 (32%), Gaps = 272/1341 (20%)
Query: 1265 GESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVD 1324
G+SP EP A S GS+ P A G + A QA S S D
Sbjct: 154 GKSPRKSAEPS-ANTTLVSETEEEGSV-PAFGAAAKPGMVSAGQADSSSE---------D 202
Query: 1325 SMPCLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDP 1384
+ D + K + + +AA+AP G G A S + G+P +D
Sbjct: 203 TSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDS 262
Query: 1385 KQGTSGGVDTSSE--------QIATLTGFPDFREHIAKIFEKPVLGALATPGEKAG--AG 1434
+ + D+ E Q A E P GA P K G
Sbjct: 263 ESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVA 322
Query: 1435 RSAVGK-------------------DLTRPLG--PEKLLDGPPGVDVT---LLPAPP--- 1467
++ GK +P G P+ P + PAPP
Sbjct: 323 KAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKT 382
Query: 1468 ----ARLQVEKKQQLA------GEAEISHLALQDPASDKLLGPAGLTWERNLPGAG-VGK 1516
A++QV K+++ + +++ LA + A K LG + + G G +GK
Sbjct: 383 GPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGK 442
Query: 1517 EMAGVPPTLREDERPEGPGAAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAA 1576
VPP P W E + S E S +P+ A +
Sbjct: 443 GAGPVPPGKVGPATPSAQVGKW---EEDSESSSEESSDSSDGEVPTAVAPAQ-EKSLGNI 498
Query: 1577 FQVAPHSHGEEAVAQDRIPSGKQHQETSACDSPHGEDGPGDFAHTGVPGHVPRSTCAPSP 1636
Q P S + Q P Q + D+ + D A + P + A +
Sbjct: 499 LQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADS---EEAPAAMTA-AQ 554
Query: 1637 QREVLTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGEVADTPLEPG 1696
+ L +P+ + P +T + V G R A G ++PA + VA P
Sbjct: 555 AKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKA-GTATSPAGSSPAVAGGTQRPA 613
Query: 1697 KVAGAAGEAEGD-----ITLSTAETQACASGDLPEAGTTRTFSVVAGDL------VLPGS 1745
+ + ++ E++ + + ++ + ++ G +A + V G L VLPG
Sbjct: 614 EDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASV----PVKGSLGQGTAPVLPGK 669
Query: 1746 CQDPACSDKAPGMEGTAALHGDSPA--------------RPQQAKEQPGPERPIPAGDGK 1791
KA E + + +S + + QAK P R P+ G
Sbjct: 670 TGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAAR-APSAKGT 728
Query: 1792 VCVSSPPEPDETHDPKLQHLAPEELHTDRESPR------PGPSMLPSVPKKDAPRVMDKV 1845
+ S P T + + +P ++ +P+ GP+ +PSV K A +
Sbjct: 729 I---SAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQT 785
Query: 1846 TSDETRGAEGTESSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAA 1905
+E G+ ES ++ E+ TLA G Q+ L SP
Sbjct: 786 GPEEDSGSSEEESD------------SEEEAETLAQVKPSGK-THQIRAALAPAKESPRK 832
Query: 1906 AHAGLPPSAAEHIVSPSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAP 1965
A PP + PS K S SEE+ E+ P
Sbjct: 833 GAAPTPPG-----------------KTGPSAAQAGKQDDSGSSSEESDSDGEA--PAAVT 873
Query: 1966 PAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFD 2025
A PP + +P S P P PR S R S S D
Sbjct: 874 SAQVIKPPLIFVDPNRS----PAGPAATPAQAQAASTPRKARASESTARSSS---SESED 926
Query: 2026 EDK-PIASSGTYNLDFDNIELVDTFQTLEPRA--------------SDAKNQEG-KVNTR 2069
ED P T + + + + + P+A SD K QEG
Sbjct: 927 EDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVS 986
Query: 2070 RKSTDSVPISKSTLSRSLSLQASDFD-----GASSSGNPEAVALAPDAYSTGSSSASSTL 2124
+K+ S+P++++ L + L+ +AS+ SSG AV P +T S S
Sbjct: 987 KKNPASLPLTQAAL-KVLAQKASEAQPPVARTQPSSGVDSAVGTLP---ATSPQSTSVQA 1042
Query: 2125 KRTKKPRPPSLKKKQTTKKPTETPPVKETQQE----PDEESLVPSG-------------- 2166
K T K R P L + Q K E+ E + +E+ P G
Sbjct: 1043 KGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSR 1102
Query: 2167 -ENLASETKTESAKTE--GPSPALLE--ETP-LEPA--VGPKAACPLDS----------- 2207
E L ET ES++ + PS +LL TP L PA KA LDS
Sbjct: 1103 TETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAK 1162
Query: 2208 -----------ESAEGVVPPASGGGRVQN--SPPVGRKTLPLTTAPEA------------ 2242
+ A G++ P +GG + +P RK P+A
Sbjct: 1163 DDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQC 1222
Query: 2243 --GEVTPSDSGGQEDSPAKGLSVRLEFDYSE--------DKSSWDNQQENPPPTKKIGKK 2292
G+ P + + S K L+ LE + + + W++++ K G +
Sbjct: 1223 LLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKR-----KLSGDQ 1277
Query: 2293 PVAKMPLRRPKMK----------KTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKW 2342
P A+ P + K K +PEK T + D+ KG +
Sbjct: 1278 PAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSL----- 1332
Query: 2343 DDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPA 2402
+ ++ P+ Q + D+S K K K E
Sbjct: 1333 ---------GSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKK 1383
Query: 2403 SAMEANGVDGDGLNKPAKKKK 2423
A +A+ D + ++ KKKK
Sbjct: 1384 KAKKASTKDSESPSQKKKKKK 1404
Score = 75.5 bits (184), Expect = 7e-13
Identities = 262/1220 (21%), Positives = 408/1220 (33%), Gaps = 246/1220 (20%)
Query: 316 NSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGH 375
++ + E E A ++ + P A + L LPS ++ +A ++A T + H
Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPS-SMKEKAKAETEKAGKTGNSMPH 141
Query: 376 PQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIP--IA 433
P TG V + +G P S +L++ TEE S+ +F AA P ++
Sbjct: 142 PATG------KTVANLLSGKSPRKSAEPSANTTLVSETEEE---GSVPAFGAAAKPGMVS 192
Query: 434 VEEPGSSSRESVSKAG-MPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVP-- 490
+ SSS ++ S + V A+++++ + + P G G V
Sbjct: 193 AGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 252
Query: 491 --APSPQERGEHLNTEQS--HEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESAR-G 545
A P+E E + E S E P K Q GA P ++P + A
Sbjct: 253 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 312
Query: 546 PPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSK 605
PPG T PAVAK + GK E EDSQ+ S +
Sbjct: 313 PPG----------KTGPAVAK--------AQAGKRE---------------EDSQSSSEE 339
Query: 606 RDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGE 665
D E +KPS A S+ + + PRKG A P +T A A K E
Sbjct: 340 SDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA---PAPPRKTGPAAAQVQVGKQEE 396
Query: 666 EDPVLPPVPDGAGEPTVPEGAIWE---GSGLQPKCPDTLQSREGLGRMESFLTLESEKSD 722
+ D E A G Q K T+ G+G +
Sbjct: 397 DSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM----GMGPLGKGAGPVPPGKV 452
Query: 723 FPPTPVAEVAPKAQEGESTLEIRKMGSCDGE-GLLTSPDQPRGPACDASRQEFHAGVPHP 781
P TP A+V ++ ES+ E S DGE +P Q + + + P
Sbjct: 453 GPATPSAQVGKWEEDSESSSE-ESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP 511
Query: 782 PQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPET-- 839
PQ A +D + S + E P + +P+ P+T
Sbjct: 512 PQKAGPVAVQVKAEKPMDNSESSEESSDS-----ADSEEAPAAMTAAQAKPALKIPQTKA 566
Query: 840 -----------SIFDVLKEQAQPPENGKETSP--SHP----GFKDQGADSSQIHVPVEPQ 882
+ V P + G TSP S P G + DSS +
Sbjct: 567 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEE 626
Query: 883 EDNNLPTHGGQEQALGSELQ---------SQLPKGTLSDTP-TSSPTDMVWESSLTEESE 932
E L GQ +++G LQ L +GT P + PT ++ E+SE
Sbjct: 627 EKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSE 686
Query: 933 LS-----------APTRQK-----------------------LPALGEKRPEGACGDGQS 958
S +P + K + A G+ A +S
Sbjct: 687 SSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRS 746
Query: 959 -SRVSPPAADVLKDFSLAGNFSR-----KETCCTGQGPNKSQQALADALEEGSQHEEA-- 1010
S+V PP + LA + K Q ++ + EE EEA
Sbjct: 747 PSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAET 806
Query: 1011 -CQRHP--------------------GASEAADG-CSPLWGLSKREMASGNTGEAPPCQP 1048
Q P GA+ G P + ++ SG++ E
Sbjct: 807 LAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDG 866
Query: 1049 DSVALLDAVPCL--------PALAPASPGVTPTQ----------DAPETEACDETQEGRQ 1090
++ A + + + P +PA P TP Q A E+ A + E
Sbjct: 867 EAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESED 926
Query: 1091 QPV-PAPQQKMECWATSDAESPKLLASFPSAGEQGGEAGAAETGGSAGAGDPGKQQAPEK 1149
+ V PA Q T+ P + P + AGA+ + S+ D KQ+ P
Sbjct: 927 EDVIPATQCLTPGIRTNVVTMP---TAHPRIAPKASMAGASSSKESSRISDGKKQEGPAT 983
Query: 1150 PGEATLSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDALLPARELGGIPRSTMD 1209
L T+ L +++ +A+ P+A Q + +G +P ++
Sbjct: 984 QVSKKNPASLPLTQAAL-------KVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQ 1036
Query: 1210 FSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESP- 1268
++ QA G ++ P P + + A ++DS + SS+ GE P
Sbjct: 1037 STSVQA---------KGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQ 1087
Query: 1269 ------CPVGEPPLALEN---------------AASLKLFAGSLAPLLQPGAAGGEIPAV 1307
VG P E A S L +G + P L P +
Sbjct: 1088 GAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS------- 1140
Query: 1308 QASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAA 1367
QAS +PK +DS P + LA G+++A AG + G A+
Sbjct: 1141 QASKATPK-------LDSSPSVS--STLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAAS 1191
Query: 1368 GETEGSMERMGEPSQDPKQG 1387
G T + S+ PK+G
Sbjct: 1192 GTTP-------QKSRKPKKG 1204
Score = 74.7 bits (182), Expect = 1e-12
Identities = 270/1291 (20%), Positives = 419/1291 (32%), Gaps = 259/1291 (20%)
Query: 14 LSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASE-SSASLDPCL 72
LS ++PR + P + + + ++ P A+ G V G ++SE +S+S D
Sbjct: 152 LSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD 211
Query: 73 V----SPEVTEPRKDPQGARGPEGS-LLPSPP--------------PSQEREHPS--SSM 111
V S ++ + R A+G G P+PP P ++ E S SS
Sbjct: 212 VEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSD 271
Query: 112 PFAECPPEGCLASPAAAPE-------DGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPY 164
E P L A+ + P +SPR+ AP PG A
Sbjct: 272 SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPA----------- 320
Query: 165 QEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFE 224
A AG+ +EE +SS S +++P + + KAP P E
Sbjct: 321 ---VAKAQAGK----REEDSQSSSEESDSEEEAPAQA----KPSGKAPQVRAASAPAK-E 368
Query: 225 SQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESS------AVLEKSPLKPMAPIP 278
S K AA PP ++ A VQV + + ES A + + +KP+ P
Sbjct: 369 SPRKGAAPA-PPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSP 427
Query: 279 Q-DPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEV-------NAASQ 330
Q PA G+G P P A P A+V ++S+
Sbjct: 428 QVKPASTMGMGPLGKGAGPVP--------------PGKVGPATPSAQVGKWEEDSESSSE 473
Query: 331 ESCQQPVG----AYLPHAELPWG---LPSPALVPEAGGSGKEALDTIDVQGHPQTGMRGT 383
ES G A P E G P P G K + VQ + M +
Sbjct: 474 ESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAG--PVAVQVKAEKPMDNS 531
Query: 384 KPNQVVCVAAGGQ--PEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAV------- 434
+ ++ +A + P +P+L P +A P + + A P+ V
Sbjct: 532 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRK 591
Query: 435 ---------------------EEPGSSSRESVS---KAGMPVSADAAKEVVDAGLVGLER 470
E SSS ES S K G+ V+ AK V GL+
Sbjct: 592 AGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK----GLQV 647
Query: 471 QVSDLGSKGEHPEGD----PGEVPAPSPQERGEHL----NTEQSHEVQPGVPPPPLPKEQ 522
+ + + KG +G PG+ Q + E ++E+ + + P K
Sbjct: 648 KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 707
Query: 523 SHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEA 582
+ Q A P ++ PG A SP+ K R+P +S
Sbjct: 708 VKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGP 767
Query: 583 PEPPDGGDPGNLQG-------EDSQAFSSKRDPEVGKDELS--KPSSD--------AESR 625
P G EDS + + D E + L+ KPS A ++
Sbjct: 768 ASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAK 827
Query: 626 DHPSSHSA-QPPRKGG-----AGHTDGPHSQTAEADASG-LPHKLGEEDPVLPPV--PDG 676
+ P +A PP K G AG D S + E+D+ G P + + PP+ D
Sbjct: 828 ESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDP 887
Query: 677 AGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDF------------- 723
P P A P ++ E R S ESE D
Sbjct: 888 NRSPAGP--AATPAQAQAASTPRKARASESTARSSS---SESEDEDVIPATQCLTPGIRT 942
Query: 724 ----PPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFHAGVP 779
PT +APKA ++ DG+ + GPA S++
Sbjct: 943 NVVTMPTAHPRIAPKASMAGASSSKESSRISDGK-------KQEGPATQVSKK------- 988
Query: 780 HPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPET 839
+P A L + A + Q + + A P S P +
Sbjct: 989 NPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATS------PQSTSVQA 1042
Query: 840 SIFDVLKEQAQPPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGS 899
+ L++ P +P + +DSS GS
Sbjct: 1043 KGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSS-----------------------GS 1079
Query: 900 ELQSQLPKGTLSD----TPTSSPTDMVWESSLTEESE--LSAPTRQKLPALGEKRPEGAC 953
E + P+G S PT S T+ + E + E SE + AP++ L G P
Sbjct: 1080 EEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLS--GYMTPGLTP 1137
Query: 954 GDGQSSRVSPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQHEEACQR 1013
+ Q+S+ +P L + S T P+ Q+A + Q
Sbjct: 1138 ANSQASKATP---------KLDSSPSVSSTLAAKDDPDGKQEA------KPQQAAGMLSP 1182
Query: 1014 HPGASEAADGCSPLWGLSKREMASGNTGEAPPCQPDSVALLDAVPCLPALAPASPGV--- 1070
G EAA G +P ++ A Q + L P A V
Sbjct: 1183 KTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKV 1242
Query: 1071 -TPTQDAPETEACDETQEGRQQPVPAPQQKMECWATSDAESPKLLASFPSAGEQGGEAG- 1128
T + + D T+E ++ + ++K+ A +P+ +GGEA
Sbjct: 1243 LTELLEQERKKVVDTTKESSRKGWESRKRKLS-GDQPAARTPRSKKKKKLGAGEGGEASV 1301
Query: 1129 ----AAETGGSAGAGDPGKQQAPEKPGEATL 1155
+ T D EK G+ +L
Sbjct: 1302 SPEKTSTTSKGKAKRDKASGDVKEKKGKGSL 1332
Score = 61.6 bits (148), Expect = 1e-08
Identities = 241/1217 (19%), Positives = 397/1217 (32%), Gaps = 207/1217 (17%)
Query: 1550 ERSRQELASGLPSPAATQ------ELPVERAAAFQVAPHSHGEEAVAQDRIPSGKQHQET 1603
E + E A P A+T +LP + G+ + +GK
Sbjct: 92 EEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANL 151
Query: 1604 SACDSPHGEDGPGD----FAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGE 1659
+ SP P + T G VP A P +++SE + + +
Sbjct: 152 LSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD 211
Query: 1660 RRPGVTAGILEMRNALGNQSTPAPPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQAC 1719
+ IL++R A S PA T TP PGK A + + +E+ +
Sbjct: 212 VEVKASEKILQVRAA----SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE 267
Query: 1720 ASGDLPE---AGTTRTFSVVAGDLVLPGSCQDPA-------CSDKAPGMEGTAALHGDSP 1769
S D E A + +G G+ PA + PG G A +
Sbjct: 268 ESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAG 327
Query: 1770 ARPQQAK----------EQPGPERP-----------IPAGDGKVCVSSPPEPDETHDPKL 1808
R + ++ E P +P PA + ++P P +T
Sbjct: 328 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAA 387
Query: 1809 QHLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAE-------GTESSPV 1861
Q ++ R S S ++ +A +V S + + A G + PV
Sbjct: 388 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPV 447
Query: 1862 ADDIIQPAAPA--------DLESPTLAAS-SYHGDVVGQV------STDLIAQSISPAAA 1906
+ PA P+ D ES + +S S G+V V S I Q+ P ++
Sbjct: 448 PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQA-KPTSS 506
Query: 1907 HAGLPPSAAEHIVSPSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPP 1966
A PP A P +V+A P D ++ SSDS ++ E P + T +A P
Sbjct: 507 PAKGPPQKA-------GPVAVQVKAEKPM--DNSESSEESSDSADSEEAPAAMTAAQAKP 557
Query: 1967 APPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDE 2026
A P + P+ +T ++ PV G ++ G+ P S +
Sbjct: 558 ALKIPQTKACPKKTNTT--------ASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGT 609
Query: 2027 DKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNT------------------ 2068
+P S + E T+ S K + K +
Sbjct: 610 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGK 669
Query: 2069 RRKSTDSVPISKSTLSRSLSLQASDFDGASSS--------------GNPEAVALAPDAYS 2114
+ V K S S S + SD + A++S NP A A AP A
Sbjct: 670 TGPTVTQVKAEKQEDSES-SEEESDSEEAAASPAQVKTSVKKTQAKANP-AAARAPSAKG 727
Query: 2115 TGSS-------SASSTLKRTKKPRPPSLKKKQTT---KKPTETPPV-------KETQQEP 2157
T S+ +A + + K +PP + +T + P P V + Q P
Sbjct: 728 TISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP 787
Query: 2158 DEESLVPSGENLASETKTESAKTEGPSP---------ALLEETPLEPAV-------GPKA 2201
+E+S S E SE + E+ PS A +E+P + A GP A
Sbjct: 788 EEDS-GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSA 846
Query: 2202 A---------CPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGG 2252
A + ++G P A +V P + P P+ +
Sbjct: 847 AQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI-------FVDPNRSPAGPAATPA 899
Query: 2253 QEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIG---KKPVAKMPLRRPKMKKTPE 2309
Q + + R + SS ++ P T+ + + V MP P++
Sbjct: 900 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAP--- 956
Query: 2310 KLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNF 2369
K AS + + +D +G T K NP S L Q++
Sbjct: 957 KASMAGASSSKESSRISDGKKQEGPATQVSKK------NPASLPLTQAALKVLAQKASEA 1010
Query: 2370 DPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTD 2429
P ++T S A +PA++ ++ V G NK K K ++
Sbjct: 1011 QPPV-----------ARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQA 1059
Query: 2430 TFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLE 2489
T + S SD S P+ +V T + + E
Sbjct: 1060 TKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEE------TAAE 1113
Query: 2490 ADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDD-------AP 2542
+ + D PS T +P + + +++ + S+L DD P
Sbjct: 1114 SSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKP 1173
Query: 2543 KKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVN--TAAKNQHPVPRGLA 2600
++ A L T + + + S P +G+ T AL + T P P A
Sbjct: 1174 QQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEA 1233
Query: 2601 PNQESHLQVPEKSSQKE 2617
Q S ++V + ++E
Sbjct: 1234 QVQASVVKVLTELLEQE 1250
Score = 48.1 bits (113), Expect = 1e-04
Identities = 149/749 (19%), Positives = 252/749 (33%), Gaps = 141/749 (18%)
Query: 4 ENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGG-FCTAS 62
E+S S + + S + +A P + +K Q R S+ G++ G TA+
Sbjct: 683 EDSESSEEESDSEE---AAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAA 739
Query: 63 ESSASLDPCLVSPEVTEPRKDPQGARGP-----------------EGSLLPSPPPSQERE 105
+ P V P V P+ ARGP G S +E +
Sbjct: 740 AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESD 799
Query: 106 HPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPG------------DIAAA 153
+ A+ P G AA P +SPR+ AP PG D + +
Sbjct: 800 SEEEAETLAQVKPSGKTHQIRAAL--APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGS 857
Query: 154 FPAERDS-------------------------------STPYQEIAAVPSAGRERQPKEE 182
E DS +TP Q AA S R+ + E
Sbjct: 858 SSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAA--STPRKARASES 915
Query: 183 GQKSSFSFSSGIDQSPG---MSP--------VPLREPM---KAPLCGEGDQPGGFESQEK 228
+SS S S D P ++P +P P KA + G +
Sbjct: 916 TARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDG 975
Query: 229 EAAGGFPPAESRQGVASVQVTPEA-PAAAQQGTESSAVLEKSPL-----KPMAPIPQDPA 282
+ G S++ AS+ +T A AQ+ +E+ + ++ + +P
Sbjct: 976 KKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSP 1035
Query: 283 PRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLP 342
S + +G + L E +A P S+ + ++ ++ S+E + P GA
Sbjct: 1036 QSTSVQAKGTNKLRKPKLP---EVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSA 1092
Query: 343 HAEL-PWGLPSPALVPEAGGSGKE-----------------ALDTIDVQGHPQTGMRGTK 384
H + P + LV E E L + Q T +
Sbjct: 1093 HTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSS 1152
Query: 385 PNQVVCVAAGGQPEGGLPVSPEPS--LLTPTEEAHPASSLASFPAAQIP-IAVEEPGSSS 441
P+ +AA P+G P+ + +L+P A+S + ++ P P +S+
Sbjct: 1153 PSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQAST 1212
Query: 442 RESVSK-----AGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQE 496
S G P + A+ V A +V + ++ L + + E +
Sbjct: 1213 LALQSNITQCLLGQPWPLNEAQ--VQASVVKVLTEL--LEQERKKVVDTTKESSRKGWES 1268
Query: 497 RGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVH 556
R L+ +Q P P K++ G P+ S +++G K
Sbjct: 1269 RKRKLSGDQ-----PAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKG--------KAK 1315
Query: 557 EDSTSPAVAKEGSRSPGDSPGGKEEAPE-------PPDGGDPGNLQGEDSQAFSSKRDPE 609
D S V ++ + S G K+E E +GGD N + + + S KR +
Sbjct: 1316 RDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKD 1375
Query: 610 VGKDELSKPSSDAESRDHPSSHSAQPPRK 638
K E K + A ++D S + +K
Sbjct: 1376 KEKKEKKKKAKKASTKDSESPSQKKKKKK 1404
>gi|226437579 NAC alpha domain containing [Homo sapiens]
Length = 1562
Score = 86.7 bits (213), Expect = 3e-16
Identities = 314/1426 (22%), Positives = 471/1426 (33%), Gaps = 211/1426 (14%)
Query: 60 TASESSASLDPCLVSPEVT-----EPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFA 114
T + A+L+P +V E T PR R EG PP + S+P
Sbjct: 107 TEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSP 166
Query: 115 ECPPEGCLASP--------AAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSS---TP 163
P+ P A P GP + R+ ++ + PA S
Sbjct: 167 PPDPDSFFTPPSTPTKTTYALLPACGPHGDA--RDSEAELRDELLDSPPASPSGSYITAD 224
Query: 164 YQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGF 223
A+ PS EG F SG SP S V RE A G + P
Sbjct: 225 GDSWASSPSCSLSLLAPAEG----LDFPSGWGLSPQGSMVDERELHPA---GTPEPPSSE 277
Query: 224 ESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQ--QGT-----ESSAVLEKSPLKPMAP 276
S +++ + + + P PAA QG+ E+ V SP +
Sbjct: 278 SSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEE 337
Query: 277 IPQDPAPRASDRERGQGEAPPQYLTDDL------EFLRACHLPRSNSGAAPEAEVNAASQ 330
DP P G+ ++ L E + R ++ AA +A+
Sbjct: 338 AVADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYA 397
Query: 331 ESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTID------VQGHPQTGMRGTK 384
E+ + + + PHA+ S E G G + L D V+ PQT RG
Sbjct: 398 EADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAY 457
Query: 385 PNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVE-EPGSSSRE 443
+Q + + EG + +TP +L P Q+ +A P + E
Sbjct: 458 LSQRQELISEVTEEGLALGQESTATVTP-------HTLQVAPGLQVEVATRVTPQAGEEE 510
Query: 444 SVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAP-SPQERGEHLN 502
+ S AG +A A + G+ + Q S K P+ + P SPQ E
Sbjct: 511 TDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGG 570
Query: 503 TEQSHEVQPGVPPPPLPKEQSHEV---QPGAPPPPLPKAPSESARGPPGPTDGAKVHEDS 559
+ +P +P++ ++ Q A PPLP ++ + P P A +
Sbjct: 571 LDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPK-PVAAATIVSQQ 629
Query: 560 TSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPS 619
A+EG P DS PP L +D++ SS P +S+ +
Sbjct: 630 -----AEEGLTLPQDS------VMTPP-------LPLQDTE-LSSAPKPVAAATLVSQQA 670
Query: 620 SDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGE 679
+ + S+ + P + TD + A A+ L + EE LP D A
Sbjct: 671 EEGLTLPQDSAMTPPLPLQD----TDLSSAPKPVAAAT-LVSQQAEEGLTLPQ--DSAMT 723
Query: 680 PTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEV----APKA 735
P +P S +P TL S++ E LTL + + PP P+ + APK
Sbjct: 724 PPLPLQDTDLSSAPKPVAAATLVSQQA----EEGLTLPQDSAMTPPLPLQDTDLSSAPKP 779
Query: 736 QEGESTLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTA 795
+ + + EGL D P + + P P + +
Sbjct: 780 VAAATIVSQQAE-----EGLTLPQDSAMTPPLPLQDTDL-SSAPKPVAAATIVSQQAEEG 833
Query: 796 LILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENG 855
L L QD P P L ++ P T + +E P++
Sbjct: 834 LTLPQDSAMTPPLP-------------LQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDS 880
Query: 856 KETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTLSDT-P 914
T P Q D S PV + G S + + LP L DT P
Sbjct: 881 AMTPP----LPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLP---LQDTGP 933
Query: 915 TSSPTDMVWESSLTEESELS-APTRQKLPALGEKRPEGACGDGQSSRVSPPAADVLKDFS 973
TS P + + T ++E AP + + + ++ A G P A K+ +
Sbjct: 934 TSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALG--------PRPAPEEKNAA 985
Query: 974 LAGNFSRKETCCTGQGPNKSQQALADALEEGSQHEEACQRHP-GASEAADGCSPLWGLSK 1032
L P + A D +++ A P A E AD + LS
Sbjct: 986 L---------------PTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSL 1030
Query: 1033 REMASGNTGEAPPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQP 1092
E ASG E ++++ CL A A G P ET + QEG +P
Sbjct: 1031 PEPASGAGEEIA----EALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKP 1086
Query: 1093 VPAPQQKMECWATSDAESPKLLASFPSAGEQGGEAGAAETGGSAGAGDPGKQQAPEKPGE 1152
+ + A+ P + + A E G +G P E
Sbjct: 1087 LAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTP----------E 1136
Query: 1153 ATLSCGLLQTEHCLTSGEEAS---TSALRESCQAEHPMASCQDALLPARELGGIPRSTMD 1209
TL + TE L S E+S S+L C S + P LG
Sbjct: 1137 PTLP-SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLG-----LGS 1190
Query: 1210 FSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPC 1269
VP L PPE A P VD G A ++ P P +PC
Sbjct: 1191 VEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEP-PAPC 1249
Query: 1270 PVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSG-------------SPKA 1316
+P E++ + GSL L P AG + PA A SG SP +
Sbjct: 1250 LCQDPQ---EDSVEDEEPPGSLG--LPPPQAGVQ-PAAAAVSGTTQPLGTGPRVSLSPHS 1303
Query: 1317 RTTEGPVDSMPCLD-RMPLL-------AKGKQATGEEKAATAPGA----------GAKAS 1358
V SM D + +L G Q+ + +AP +A
Sbjct: 1304 PLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRAL 1363
Query: 1359 GEGMAGDAAGETEGSMERMG----EPSQDPKQGTSGGVDTSSEQIA 1400
G G D+ GE+ ++ + Q P Q +GG S E IA
Sbjct: 1364 GSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGG---SEETIA 1406
Score = 53.9 bits (128), Expect = 2e-06
Identities = 328/1550 (21%), Positives = 524/1550 (33%), Gaps = 269/1550 (17%)
Query: 547 PGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNL---QGEDSQAFS 603
PGP+ A S A + S PGG A P G P + +G SQA S
Sbjct: 47 PGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALS 106
Query: 604 SKRD-PEVGKDELSKPSSDAESRDHP-SSHSAQPPRKGGAGHTDGPHSQTAEADASGLPH 661
++ P + + ++ P ++ +A ++GG D P ++ D S
Sbjct: 107 TEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSV--- 163
Query: 662 KLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKS 721
P PP PD P P L P C +R+ S L E
Sbjct: 164 ------PSPPPDPDSFFTP--PSTPTKTTYALLPACGPHGDARD------SEAELRDELL 209
Query: 722 DFPPTPVAEVAPKAQEGES-----TLEIRKMGSCDGEGLLTSPD----QPRGPACDASRQ 772
D PP + A +G+S + + + +G L P P+G D +
Sbjct: 210 DSPPASPSGSYITA-DGDSWASSPSCSLSLLAPAEG---LDFPSGWGLSPQGSMVD--ER 263
Query: 773 EFH-AGVPHPPQGEN-LAADL----GLTALILDQD----QQGIPSC--PGEGWI--RGAA 818
E H AG P PP E+ L+AD G D D IP+ P +G + + A
Sbjct: 264 ELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEA 323
Query: 819 SEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGK-----------ETSPSHPGFKD 867
E LS E+ + + A P+ D+ E + + E F+D
Sbjct: 324 VEVTPLSPEEEEEEAVADPDPG-GDLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRD 382
Query: 868 QGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPK----------------GTLS 911
+ +S E ++ + G+ A + LQ + K GT+S
Sbjct: 383 DTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVS 442
Query: 912 DTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRPEGACGDGQ----------SSRV 961
++P + L++ EL + ++ ALG++ ++RV
Sbjct: 443 WAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRV 502
Query: 962 SPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQHEEAC---QRHPGAS 1018
+P A + D S AG S P SQ+ +++ L + S E Q +
Sbjct: 503 TPQAGEEETD-STAGQESAAMAM-----PQPSQEGISEILGQESVTAEKLPTPQEETSLT 556
Query: 1019 EAADGCSPLWGLSKREMASGNTGEAPPCQPDSVALLD-AVPCLPALAPASP------GVT 1071
D L ++ SG A A D +P A+ P P
Sbjct: 557 LCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSA 616
Query: 1072 PTQDAPETEACDETQEGRQQP---VPAPQQKMECWATSDAESPKLLASFPSAGEQGG--- 1125
P A T + +EG P V P ++ S A P A+ S + G
Sbjct: 617 PKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTL 676
Query: 1126 -------------EAGAAETGGSAGAGDPGKQQAPEK---PGEATLSCGLLQTEHCLTSG 1169
+ + A QQA E P ++ ++ L + L+S
Sbjct: 677 PQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA 736
Query: 1170 EEASTSALRESCQAEHPMASCQDAL------LPARELGGIPR-----STMDFSTHQAVPD 1218
+ +A S QAE + QD+ L +L P+ + + + +
Sbjct: 737 PKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTL 796
Query: 1219 PKELLLSGP-----PEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAP------GES 1267
P++ ++ P ++++ P +Q+ E + S+ P P +
Sbjct: 797 PQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA 856
Query: 1268 PCPVGEP-PLALENAASLKLFAGSLA----PLLQPGAAGGEIPAVQASSGSPKARTTEG- 1321
P PV P++ + L L S PL + P A+ S +A EG
Sbjct: 857 PKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAE--EGL 914
Query: 1322 --PVDS-----MPCLDRMPL-----LAKGKQATGEEKAATAPGAGAKAS-GEGMAGDAAG 1368
P DS +P D P LA T + +A APG A+ + G+A G
Sbjct: 915 TLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALG 974
Query: 1369 ETEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVLG--ALAT 1426
E+ P+ V Q A G P + A LG AL+
Sbjct: 975 PRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD----STLGMEALSL 1030
Query: 1427 PGEKAGAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPAR--LQVEKKQQ------- 1477
P +GAG + + L+RP G E L+ P P + L+VE +Q+
Sbjct: 1031 PEPASGAGEE-IAEALSRP-GREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLA 1088
Query: 1478 --------LAGEAEISHL---ALQDPASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLR 1526
L G E+ A + + +LL PA ER L G + PTL
Sbjct: 1089 QEHGPRSALGGAREVPDAPPAACPEVSQARLLSPA--REERGLSGKSTPE------PTLP 1140
Query: 1527 EDERPEGPGAAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGE 1586
E + P A S L+R + + +P + Q PV + + H
Sbjct: 1141 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVE---QPHEV 1197
Query: 1587 EAVAQDRIPSGKQH----QETSACDSPHGED--GPGDFAHTGVPGHVPRSTC-APSPQRE 1639
+V + ++ Q ++ D P G D PG A +P P + C PQ +
Sbjct: 1198 PSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQED 1257
Query: 1640 VLTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGEVADTPLEPGKVA 1699
+ E P +L P AG+ A+ + P V+ +P P
Sbjct: 1258 SV---EDEEPPGSLGL------PPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSP 1308
Query: 1700 GAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGME 1759
A D+ L +LP CQ P S G +
Sbjct: 1309 KVASMDAKDLALQ----------------------------ILP-PCQVPPPS----GPQ 1335
Query: 1760 GTAALHGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTD 1819
A G S Q+ ++ + P G G+ S E + + LAP+ +
Sbjct: 1336 SPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDI--LAPQTVQCP 1393
Query: 1820 RESPRPGPSMLPSVPK-----KDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADL 1874
++P G + K K A + M K+ + +G + + A P
Sbjct: 1394 AQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVF 1453
Query: 1875 ESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAP 1924
+SP A+ +Y V G+ + ++Q + AAA PS +V SAP
Sbjct: 1454 KSP--ASDTYV--VFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAP 1499
Score = 43.9 bits (102), Expect = 0.002
Identities = 156/706 (22%), Positives = 252/706 (35%), Gaps = 99/706 (14%)
Query: 1660 RRPGVTAGILEMRNALGNQSTPA--PPTGEVADTPLEPG-------KVAGAAGEAEGDIT 1710
+R + + + E ALG +ST P T +VA PG +V AGE E D T
Sbjct: 460 QRQELISEVTEEGLALGQESTATVTPHTLQVA-----PGLQVEVATRVTPQAGEEETDST 514
Query: 1711 LSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAALHGDSPA 1770
E+ A A + G + Q+ ++K P + +L P
Sbjct: 515 AGQ-ESAAMAMPQPSQEGISEILG------------QESVTAEKLPTPQEETSLTL-CPD 560
Query: 1771 RPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPSML 1830
PQ KE+ G + +P+G V ++ + A E+L ++S P L
Sbjct: 561 SPQNLKEEGGLD--LPSGRKPVAAATI----------VPRQAKEDLTLPQDSAMTPPLPL 608
Query: 1831 PSVPKKDAPRVMDKVTSDETRGAEG---------TESSPVADDIIQPAAPADLESPTLAA 1881
AP+ + T + EG T P+ D + +AP + + TL +
Sbjct: 609 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELS-SAPKPVAAATLVS 667
Query: 1882 S-SYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAG---DRVEASTPSCP 1937
+ G + Q S + + P AA +VS A G + A TP P
Sbjct: 668 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLP 727
Query: 1938 DPAKDLSR-----------SSDSEEAFETPES---TTPVKAPPAPPPPPPEVIPEPEVST 1983
DLS S +EE P+ T P+ P+ + + +
Sbjct: 728 LQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVS 787
Query: 1984 QPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHS--FSAVFDEDKPIASSGTYNLDFD 2041
Q E ++ P P D+ S +P + + S +E +
Sbjct: 788 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMT---P 844
Query: 2042 NIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSG 2101
+ L DT + P+ A V+ + + ++P S ++ L LQ +D A
Sbjct: 845 PLPLQDTDLSSAPKPVAAATP---VSQQAEEGLTLP-QDSAMTPPLPLQDTDLSSA---- 896
Query: 2102 NPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEES 2161
P+ VA A S + + + + P L+ T P E V Q E
Sbjct: 897 -PKPVAAATPV-SQQAEEGLTLPQDSAMTAPLPLQDTGPTSGP-EPLAVATPQTLQAEAG 953
Query: 2162 LVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGG 2221
P E +A+ + E + GP PA E+ P V AA LD + P A G
Sbjct: 954 CAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAA--LDQVQQDDPQPAAEAG- 1010
Query: 2222 RVQNSPPVGRKTLPLTTAPEAGEV-TPSDSGGQEDSPA---KGLSVRLEF-DYSEDKSSW 2276
+P ++ T EA + P+ G+E + A G LE ++ D +
Sbjct: 1011 ----TPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKP 1066
Query: 2277 DNQQENP---PPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPP 2319
D+ Q+ ++ G KP+A+ R + E D PA+ P
Sbjct: 1067 DSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACP 1112
Score = 42.4 bits (98), Expect = 0.007
Identities = 225/1104 (20%), Positives = 368/1104 (33%), Gaps = 174/1104 (15%)
Query: 1634 PSPQREVLTVPEANSEPW-------TLDTLGGERRPGVTAGILEMRNAL-----GNQSTP 1681
P P ++ +S W LD L + P + A +L + +L + TP
Sbjct: 271 PEPPSSESSLSADSSSSWGQEGHFFDLDFLAND--PMIPAALLPFQGSLIFQVEAVEVTP 328
Query: 1682 APPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLV 1741
P E + +P AGE E D T S + Q+ + + E G F+ D
Sbjct: 329 LSPEEEEEEAVADPDPGGDLAGEGEEDST-SASFLQSLSDLSITE-GMDEAFA-FRDDTS 385
Query: 1742 LPGSCQDPACSDKAPG-------MEGTAALHGDSPARPQQAKEQPGPERPIPAGDGKV-- 1792
S D A +A A L DS + ++ E G + + A DG V
Sbjct: 386 AASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEE--ESGGGAKGLQAQDGTVSW 443
Query: 1793 CVSSPPEPDE------THDPKLQHLAPEELHTDRESPRPGP----SMLPSVPKKDAPRVM 1842
V + P+ + + + E L +ES + P + + A RV
Sbjct: 444 AVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVT 503
Query: 1843 DKVTSDETRGAEGTESSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSIS 1902
+ +ET G ES+ +A + P+ S +++GQ S
Sbjct: 504 PQAGEEETDSTAGQESAAMA-----------MPQPSQEGIS---EILGQESVTAEKLPTP 549
Query: 1903 PAAAHAGLPPSAAEHIVSPSA---PAGDRVEASTPSCPDPAK-DLSRSSDSEEAFETPES 1958
L P + +++ P+G + A+ P AK DL+ DS P
Sbjct: 550 QEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQ 609
Query: 1959 TTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSH 2018
T + + P P + + +Q E ++V P P D+ S +P +
Sbjct: 610 DTDLSSAPKP-------VAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAA 662
Query: 2019 S--FSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSV 2076
+ S +E + + L DT + P+ A V+ + + ++
Sbjct: 663 ATLVSQQAEEGLTLPQDSAMT---PPLPLQDTDLSSAPKPVAAAT---LVSQQAEEGLTL 716
Query: 2077 PISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPP-SL 2135
P S ++ L LQ +D A P+ VA A + + TL + PP L
Sbjct: 717 P-QDSAMTPPLPLQDTDLSSA-----PKPVAAA--TLVSQQAEEGLTLPQDSAMTPPLPL 768
Query: 2136 KKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEP 2195
+ + P Q+ +E +P +SA T P L++T L
Sbjct: 769 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQ----------DSAMT---PPLPLQDTDLSS 815
Query: 2196 AVGPKAACPLDSESA-EGVVPPASGGGRVQNSPPVGRKTLPLTTAP-------------E 2241
A P AA + S+ A EG+ P +PP+ + L++AP E
Sbjct: 816 APKPVAAATIVSQQAEEGLTLPQDSA----MTPPLPLQDTDLSSAPKPVAAATPVSQQAE 871
Query: 2242 AGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRR 2301
G P DS P + + ++ +QQ T A +PL+
Sbjct: 872 EGLTLPQDSAMTPPLPLQDTDLS-SAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQD 930
Query: 2302 PKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTF---DIDKWDDPNFNPFSSTSKMQ- 2357
PE L A+P AE P + T ++ + P P + +
Sbjct: 931 TGPTSGPEPL--AVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPT 988
Query: 2358 -ESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLN 2416
P Q DP E+ P+ S+ S PAS A + L+
Sbjct: 989 VPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASG--AGEEIAEALS 1046
Query: 2417 KPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAV 2476
+P ++ + T A P++P + V E L
Sbjct: 1047 RPGREACLEARAHT--------------------GDGAKPDSPQKETLEVENQQEGGLKP 1086
Query: 2477 TNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLP 2536
Q+ + L ++ P V++ + SP E G S P
Sbjct: 1087 LAQEHGPRSA-LGGAREVPDAPPAACPEVSQARLLSPAR----------EERGLSGKSTP 1135
Query: 2537 QDDDAPKKQALYLMFDTSQES---PVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQ- 2592
+ P A D+ ES V S ++P P S + ++ E ++ + Q
Sbjct: 1136 -EPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQP 1194
Query: 2593 HPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLA-- 2650
H VP L LQ PE + G PS ++ P G SA L+ A
Sbjct: 1195 HEVPSVLG---TPLLQPPEN--------LAKGQPSTPVD--RPLGPDPSAPGTLAGAALP 1241
Query: 2651 --HPVSLCGALDYLEPDLAEKNPP 2672
P + C D E + ++ PP
Sbjct: 1242 PLEPPAPCLCQDPQEDSVEDEEPP 1265
>gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1562
Score = 86.7 bits (213), Expect = 3e-16
Identities = 314/1426 (22%), Positives = 471/1426 (33%), Gaps = 211/1426 (14%)
Query: 60 TASESSASLDPCLVSPEVT-----EPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFA 114
T + A+L+P +V E T PR R EG PP + S+P
Sbjct: 107 TEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSP 166
Query: 115 ECPPEGCLASP--------AAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSS---TP 163
P+ P A P GP + R+ ++ + PA S
Sbjct: 167 PPDPDSFFTPPSTPTKTTYALLPACGPHGDA--RDSEAELRDELLDSPPASPSGSYITAD 224
Query: 164 YQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGF 223
A+ PS EG F SG SP S V RE A G + P
Sbjct: 225 GDSWASSPSCSLSLLAPAEG----LDFPSGWGLSPQGSMVDERELHPA---GTPEPPSSE 277
Query: 224 ESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQ--QGT-----ESSAVLEKSPLKPMAP 276
S +++ + + + P PAA QG+ E+ V SP +
Sbjct: 278 SSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEE 337
Query: 277 IPQDPAPRASDRERGQGEAPPQYLTDDL------EFLRACHLPRSNSGAAPEAEVNAASQ 330
DP P G+ ++ L E + R ++ AA +A+
Sbjct: 338 AVADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYA 397
Query: 331 ESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTID------VQGHPQTGMRGTK 384
E+ + + + PHA+ S E G G + L D V+ PQT RG
Sbjct: 398 EADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAY 457
Query: 385 PNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVE-EPGSSSRE 443
+Q + + EG + +TP +L P Q+ +A P + E
Sbjct: 458 LSQRQELISEVTEEGLALGQESTATVTP-------HTLQVAPGLQVEVATRVTPQAGEEE 510
Query: 444 SVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAP-SPQERGEHLN 502
+ S AG +A A + G+ + Q S K P+ + P SPQ E
Sbjct: 511 TDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGG 570
Query: 503 TEQSHEVQPGVPPPPLPKEQSHEV---QPGAPPPPLPKAPSESARGPPGPTDGAKVHEDS 559
+ +P +P++ ++ Q A PPLP ++ + P P A +
Sbjct: 571 LDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPK-PVAAATIVSQQ 629
Query: 560 TSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPS 619
A+EG P DS PP L +D++ SS P +S+ +
Sbjct: 630 -----AEEGLTLPQDS------VMTPP-------LPLQDTE-LSSAPKPVAAATLVSQQA 670
Query: 620 SDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGE 679
+ + S+ + P + TD + A A+ L + EE LP D A
Sbjct: 671 EEGLTLPQDSAMTPPLPLQD----TDLSSAPKPVAAAT-LVSQQAEEGLTLPQ--DSAMT 723
Query: 680 PTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEV----APKA 735
P +P S +P TL S++ E LTL + + PP P+ + APK
Sbjct: 724 PPLPLQDTDLSSAPKPVAAATLVSQQA----EEGLTLPQDSAMTPPLPLQDTDLSSAPKP 779
Query: 736 QEGESTLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTA 795
+ + + EGL D P + + P P + +
Sbjct: 780 VAAATIVSQQAE-----EGLTLPQDSAMTPPLPLQDTDL-SSAPKPVAAATIVSQQAEEG 833
Query: 796 LILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENG 855
L L QD P P L ++ P T + +E P++
Sbjct: 834 LTLPQDSAMTPPLP-------------LQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDS 880
Query: 856 KETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTLSDT-P 914
T P Q D S PV + G S + + LP L DT P
Sbjct: 881 AMTPP----LPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLP---LQDTGP 933
Query: 915 TSSPTDMVWESSLTEESELS-APTRQKLPALGEKRPEGACGDGQSSRVSPPAADVLKDFS 973
TS P + + T ++E AP + + + ++ A G P A K+ +
Sbjct: 934 TSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALG--------PRPAPEEKNAA 985
Query: 974 LAGNFSRKETCCTGQGPNKSQQALADALEEGSQHEEACQRHP-GASEAADGCSPLWGLSK 1032
L P + A D +++ A P A E AD + LS
Sbjct: 986 L---------------PTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSL 1030
Query: 1033 REMASGNTGEAPPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQP 1092
E ASG E ++++ CL A A G P ET + QEG +P
Sbjct: 1031 PEPASGAGEEIA----EALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKP 1086
Query: 1093 VPAPQQKMECWATSDAESPKLLASFPSAGEQGGEAGAAETGGSAGAGDPGKQQAPEKPGE 1152
+ + A+ P + + A E G +G P E
Sbjct: 1087 LAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTP----------E 1136
Query: 1153 ATLSCGLLQTEHCLTSGEEAS---TSALRESCQAEHPMASCQDALLPARELGGIPRSTMD 1209
TL + TE L S E+S S+L C S + P LG
Sbjct: 1137 PTLP-SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLG-----LGS 1190
Query: 1210 FSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPC 1269
VP L PPE A P VD G A ++ P P +PC
Sbjct: 1191 VEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEP-PAPC 1249
Query: 1270 PVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSG-------------SPKA 1316
+P E++ + GSL L P AG + PA A SG SP +
Sbjct: 1250 LCQDPQ---EDSVEDEEPPGSLG--LPPPQAGVQ-PAAAAVSGTTQPLGTGPRVSLSPHS 1303
Query: 1317 RTTEGPVDSMPCLD-RMPLL-------AKGKQATGEEKAATAPGA----------GAKAS 1358
V SM D + +L G Q+ + +AP +A
Sbjct: 1304 PLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRAL 1363
Query: 1359 GEGMAGDAAGETEGSMERMG----EPSQDPKQGTSGGVDTSSEQIA 1400
G G D+ GE+ ++ + Q P Q +GG S E IA
Sbjct: 1364 GSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGG---SEETIA 1406
Score = 53.9 bits (128), Expect = 2e-06
Identities = 328/1550 (21%), Positives = 524/1550 (33%), Gaps = 269/1550 (17%)
Query: 547 PGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNL---QGEDSQAFS 603
PGP+ A S A + S PGG A P G P + +G SQA S
Sbjct: 47 PGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALS 106
Query: 604 SKRD-PEVGKDELSKPSSDAESRDHP-SSHSAQPPRKGGAGHTDGPHSQTAEADASGLPH 661
++ P + + ++ P ++ +A ++GG D P ++ D S
Sbjct: 107 TEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSV--- 163
Query: 662 KLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKS 721
P PP PD P P L P C +R+ S L E
Sbjct: 164 ------PSPPPDPDSFFTP--PSTPTKTTYALLPACGPHGDARD------SEAELRDELL 209
Query: 722 DFPPTPVAEVAPKAQEGES-----TLEIRKMGSCDGEGLLTSPD----QPRGPACDASRQ 772
D PP + A +G+S + + + +G L P P+G D +
Sbjct: 210 DSPPASPSGSYITA-DGDSWASSPSCSLSLLAPAEG---LDFPSGWGLSPQGSMVD--ER 263
Query: 773 EFH-AGVPHPPQGEN-LAADL----GLTALILDQD----QQGIPSC--PGEGWI--RGAA 818
E H AG P PP E+ L+AD G D D IP+ P +G + + A
Sbjct: 264 ELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEA 323
Query: 819 SEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGK-----------ETSPSHPGFKD 867
E LS E+ + + A P+ D+ E + + E F+D
Sbjct: 324 VEVTPLSPEEEEEEAVADPDPG-GDLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRD 382
Query: 868 QGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPK----------------GTLS 911
+ +S E ++ + G+ A + LQ + K GT+S
Sbjct: 383 DTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVS 442
Query: 912 DTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRPEGACGDGQ----------SSRV 961
++P + L++ EL + ++ ALG++ ++RV
Sbjct: 443 WAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRV 502
Query: 962 SPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQHEEAC---QRHPGAS 1018
+P A + D S AG S P SQ+ +++ L + S E Q +
Sbjct: 503 TPQAGEEETD-STAGQESAAMAM-----PQPSQEGISEILGQESVTAEKLPTPQEETSLT 556
Query: 1019 EAADGCSPLWGLSKREMASGNTGEAPPCQPDSVALLD-AVPCLPALAPASP------GVT 1071
D L ++ SG A A D +P A+ P P
Sbjct: 557 LCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSA 616
Query: 1072 PTQDAPETEACDETQEGRQQP---VPAPQQKMECWATSDAESPKLLASFPSAGEQGG--- 1125
P A T + +EG P V P ++ S A P A+ S + G
Sbjct: 617 PKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTL 676
Query: 1126 -------------EAGAAETGGSAGAGDPGKQQAPEK---PGEATLSCGLLQTEHCLTSG 1169
+ + A QQA E P ++ ++ L + L+S
Sbjct: 677 PQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA 736
Query: 1170 EEASTSALRESCQAEHPMASCQDAL------LPARELGGIPR-----STMDFSTHQAVPD 1218
+ +A S QAE + QD+ L +L P+ + + + +
Sbjct: 737 PKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTL 796
Query: 1219 PKELLLSGP-----PEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAP------GES 1267
P++ ++ P ++++ P +Q+ E + S+ P P +
Sbjct: 797 PQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA 856
Query: 1268 PCPVGEP-PLALENAASLKLFAGSLA----PLLQPGAAGGEIPAVQASSGSPKARTTEG- 1321
P PV P++ + L L S PL + P A+ S +A EG
Sbjct: 857 PKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAE--EGL 914
Query: 1322 --PVDS-----MPCLDRMPL-----LAKGKQATGEEKAATAPGAGAKAS-GEGMAGDAAG 1368
P DS +P D P LA T + +A APG A+ + G+A G
Sbjct: 915 TLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALG 974
Query: 1369 ETEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVLG--ALAT 1426
E+ P+ V Q A G P + A LG AL+
Sbjct: 975 PRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD----STLGMEALSL 1030
Query: 1427 PGEKAGAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPAR--LQVEKKQQ------- 1477
P +GAG + + L+RP G E L+ P P + L+VE +Q+
Sbjct: 1031 PEPASGAGEE-IAEALSRP-GREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLA 1088
Query: 1478 --------LAGEAEISHL---ALQDPASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLR 1526
L G E+ A + + +LL PA ER L G + PTL
Sbjct: 1089 QEHGPRSALGGAREVPDAPPAACPEVSQARLLSPA--REERGLSGKSTPE------PTLP 1140
Query: 1527 EDERPEGPGAAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGE 1586
E + P A S L+R + + +P + Q PV + + H
Sbjct: 1141 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVE---QPHEV 1197
Query: 1587 EAVAQDRIPSGKQH----QETSACDSPHGED--GPGDFAHTGVPGHVPRSTC-APSPQRE 1639
+V + ++ Q ++ D P G D PG A +P P + C PQ +
Sbjct: 1198 PSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQED 1257
Query: 1640 VLTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGEVADTPLEPGKVA 1699
+ E P +L P AG+ A+ + P V+ +P P
Sbjct: 1258 SV---EDEEPPGSLGL------PPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSP 1308
Query: 1700 GAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGME 1759
A D+ L +LP CQ P S G +
Sbjct: 1309 KVASMDAKDLALQ----------------------------ILP-PCQVPPPS----GPQ 1335
Query: 1760 GTAALHGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTD 1819
A G S Q+ ++ + P G G+ S E + + LAP+ +
Sbjct: 1336 SPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDI--LAPQTVQCP 1393
Query: 1820 RESPRPGPSMLPSVPK-----KDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADL 1874
++P G + K K A + M K+ + +G + + A P
Sbjct: 1394 AQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVF 1453
Query: 1875 ESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAP 1924
+SP A+ +Y V G+ + ++Q + AAA PS +V SAP
Sbjct: 1454 KSP--ASDTYV--VFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAP 1499
Score = 43.9 bits (102), Expect = 0.002
Identities = 156/706 (22%), Positives = 252/706 (35%), Gaps = 99/706 (14%)
Query: 1660 RRPGVTAGILEMRNALGNQSTPA--PPTGEVADTPLEPG-------KVAGAAGEAEGDIT 1710
+R + + + E ALG +ST P T +VA PG +V AGE E D T
Sbjct: 460 QRQELISEVTEEGLALGQESTATVTPHTLQVA-----PGLQVEVATRVTPQAGEEETDST 514
Query: 1711 LSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAALHGDSPA 1770
E+ A A + G + Q+ ++K P + +L P
Sbjct: 515 AGQ-ESAAMAMPQPSQEGISEILG------------QESVTAEKLPTPQEETSLTL-CPD 560
Query: 1771 RPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPSML 1830
PQ KE+ G + +P+G V ++ + A E+L ++S P L
Sbjct: 561 SPQNLKEEGGLD--LPSGRKPVAAATI----------VPRQAKEDLTLPQDSAMTPPLPL 608
Query: 1831 PSVPKKDAPRVMDKVTSDETRGAEG---------TESSPVADDIIQPAAPADLESPTLAA 1881
AP+ + T + EG T P+ D + +AP + + TL +
Sbjct: 609 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELS-SAPKPVAAATLVS 667
Query: 1882 S-SYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAG---DRVEASTPSCP 1937
+ G + Q S + + P AA +VS A G + A TP P
Sbjct: 668 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLP 727
Query: 1938 DPAKDLSR-----------SSDSEEAFETPES---TTPVKAPPAPPPPPPEVIPEPEVST 1983
DLS S +EE P+ T P+ P+ + + +
Sbjct: 728 LQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVS 787
Query: 1984 QPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHS--FSAVFDEDKPIASSGTYNLDFD 2041
Q E ++ P P D+ S +P + + S +E +
Sbjct: 788 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMT---P 844
Query: 2042 NIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSG 2101
+ L DT + P+ A V+ + + ++P S ++ L LQ +D A
Sbjct: 845 PLPLQDTDLSSAPKPVAAATP---VSQQAEEGLTLP-QDSAMTPPLPLQDTDLSSA---- 896
Query: 2102 NPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEES 2161
P+ VA A S + + + + P L+ T P E V Q E
Sbjct: 897 -PKPVAAATPV-SQQAEEGLTLPQDSAMTAPLPLQDTGPTSGP-EPLAVATPQTLQAEAG 953
Query: 2162 LVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGG 2221
P E +A+ + E + GP PA E+ P V AA LD + P A G
Sbjct: 954 CAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAA--LDQVQQDDPQPAAEAG- 1010
Query: 2222 RVQNSPPVGRKTLPLTTAPEAGEV-TPSDSGGQEDSPA---KGLSVRLEF-DYSEDKSSW 2276
+P ++ T EA + P+ G+E + A G LE ++ D +
Sbjct: 1011 ----TPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKP 1066
Query: 2277 DNQQENP---PPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPP 2319
D+ Q+ ++ G KP+A+ R + E D PA+ P
Sbjct: 1067 DSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACP 1112
Score = 42.4 bits (98), Expect = 0.007
Identities = 225/1104 (20%), Positives = 368/1104 (33%), Gaps = 174/1104 (15%)
Query: 1634 PSPQREVLTVPEANSEPW-------TLDTLGGERRPGVTAGILEMRNAL-----GNQSTP 1681
P P ++ +S W LD L + P + A +L + +L + TP
Sbjct: 271 PEPPSSESSLSADSSSSWGQEGHFFDLDFLAND--PMIPAALLPFQGSLIFQVEAVEVTP 328
Query: 1682 APPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLV 1741
P E + +P AGE E D T S + Q+ + + E G F+ D
Sbjct: 329 LSPEEEEEEAVADPDPGGDLAGEGEEDST-SASFLQSLSDLSITE-GMDEAFA-FRDDTS 385
Query: 1742 LPGSCQDPACSDKAPG-------MEGTAALHGDSPARPQQAKEQPGPERPIPAGDGKV-- 1792
S D A +A A L DS + ++ E G + + A DG V
Sbjct: 386 AASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEE--ESGGGAKGLQAQDGTVSW 443
Query: 1793 CVSSPPEPDE------THDPKLQHLAPEELHTDRESPRPGP----SMLPSVPKKDAPRVM 1842
V + P+ + + + E L +ES + P + + A RV
Sbjct: 444 AVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVT 503
Query: 1843 DKVTSDETRGAEGTESSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSIS 1902
+ +ET G ES+ +A + P+ S +++GQ S
Sbjct: 504 PQAGEEETDSTAGQESAAMA-----------MPQPSQEGIS---EILGQESVTAEKLPTP 549
Query: 1903 PAAAHAGLPPSAAEHIVSPSA---PAGDRVEASTPSCPDPAK-DLSRSSDSEEAFETPES 1958
L P + +++ P+G + A+ P AK DL+ DS P
Sbjct: 550 QEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQ 609
Query: 1959 TTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSH 2018
T + + P P + + +Q E ++V P P D+ S +P +
Sbjct: 610 DTDLSSAPKP-------VAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAA 662
Query: 2019 S--FSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSV 2076
+ S +E + + L DT + P+ A V+ + + ++
Sbjct: 663 ATLVSQQAEEGLTLPQDSAMT---PPLPLQDTDLSSAPKPVAAAT---LVSQQAEEGLTL 716
Query: 2077 PISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPP-SL 2135
P S ++ L LQ +D A P+ VA A + + TL + PP L
Sbjct: 717 P-QDSAMTPPLPLQDTDLSSA-----PKPVAAA--TLVSQQAEEGLTLPQDSAMTPPLPL 768
Query: 2136 KKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEP 2195
+ + P Q+ +E +P +SA T P L++T L
Sbjct: 769 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQ----------DSAMT---PPLPLQDTDLSS 815
Query: 2196 AVGPKAACPLDSESA-EGVVPPASGGGRVQNSPPVGRKTLPLTTAP-------------E 2241
A P AA + S+ A EG+ P +PP+ + L++AP E
Sbjct: 816 APKPVAAATIVSQQAEEGLTLPQDSA----MTPPLPLQDTDLSSAPKPVAAATPVSQQAE 871
Query: 2242 AGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRR 2301
G P DS P + + ++ +QQ T A +PL+
Sbjct: 872 EGLTLPQDSAMTPPLPLQDTDLS-SAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQD 930
Query: 2302 PKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTF---DIDKWDDPNFNPFSSTSKMQ- 2357
PE L A+P AE P + T ++ + P P + +
Sbjct: 931 TGPTSGPEPL--AVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPT 988
Query: 2358 -ESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLN 2416
P Q DP E+ P+ S+ S PAS A + L+
Sbjct: 989 VPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASG--AGEEIAEALS 1046
Query: 2417 KPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAV 2476
+P ++ + T A P++P + V E L
Sbjct: 1047 RPGREACLEARAHT--------------------GDGAKPDSPQKETLEVENQQEGGLKP 1086
Query: 2477 TNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLP 2536
Q+ + L ++ P V++ + SP E G S P
Sbjct: 1087 LAQEHGPRSA-LGGAREVPDAPPAACPEVSQARLLSPAR----------EERGLSGKSTP 1135
Query: 2537 QDDDAPKKQALYLMFDTSQES---PVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQ- 2592
+ P A D+ ES V S ++P P S + ++ E ++ + Q
Sbjct: 1136 -EPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQP 1194
Query: 2593 HPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLA-- 2650
H VP L LQ PE + G PS ++ P G SA L+ A
Sbjct: 1195 HEVPSVLG---TPLLQPPEN--------LAKGQPSTPVD--RPLGPDPSAPGTLAGAALP 1241
Query: 2651 --HPVSLCGALDYLEPDLAEKNPP 2672
P + C D E + ++ PP
Sbjct: 1242 PLEPPAPCLCQDPQEDSVEDEEPP 1265
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 85.1 bits (209), Expect = 9e-16
Identities = 267/1330 (20%), Positives = 433/1330 (32%), Gaps = 234/1330 (17%)
Query: 1247 GAEDSGVKAVSSADPRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPA 1306
G DS + SS+ E V + + ++ + A AP PG G P
Sbjct: 194 GQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPA--PGKVGDVTPQ 251
Query: 1307 VQASSGSPKART------TEGPVDSMPCLDRMPLLAKGKQATGEE----KAATAPGAGAK 1356
V+ + P R +E + + P + + E+ +AA+AP G
Sbjct: 252 VKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTP 311
Query: 1357 ASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGGVDTSSE--------QIATLTGFPDF 1408
G A S + G+P +D + + D+ E Q
Sbjct: 312 GKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQV 371
Query: 1409 REHIAKIFEKPVLGALATPGEKAG--AGRSAVGK-------------------DLTRPLG 1447
A E P GA P K G ++ GK +P G
Sbjct: 372 GAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSG 431
Query: 1448 --PEKLLDGPPGVDVT---LLPAPP-------ARLQVEKKQQLA------GEAEISHLAL 1489
P+ P + PAPP A++QV K+++ + +++ LA
Sbjct: 432 KAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAA 491
Query: 1490 QDPASDKLLGPAGLTWERNLPGAG-VGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQ 1548
+ A K LG + + G G +GK VPP P W E + S
Sbjct: 492 MNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKW---EEDSESS 548
Query: 1549 LERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSGKQHQETSACDS 1608
E S +P+ A + Q P S + Q P Q + D+
Sbjct: 549 SEESSDSSDGEVPTAVAPAQ-EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDN 607
Query: 1609 PHGEDGPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAGI 1668
+ D A + P + A + + L +P+ + P +T + V G
Sbjct: 608 SESSEESSDSADS---EEAPAAMTA-AQAKPALKIPQTKACPKKTNTTASAKVAPVRVGT 663
Query: 1669 LEMRNALGNQSTPAPPTGEVADTPLEPGKVAGAAGEAEGD-----ITLSTAETQACASGD 1723
R A G ++PA + VA P + + ++ E++ + + ++ + ++ G
Sbjct: 664 QAPRKA-GTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL 722
Query: 1724 LPEAGTTRTFSVVAGDL------VLPGSCQDPACSDKAPGMEGTAALHGDSPA------- 1770
+A + V G L VLPG KA E + + +S +
Sbjct: 723 QVKAASV----PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 778
Query: 1771 -------RPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESP 1823
+ QAK P R P+ G + S P T + + +P ++ +P
Sbjct: 779 AQVKTSVKKTQAKANPAAAR-APSAKGTI---SAPGKVVTAAAQAKQRSPSKVKPPVRNP 834
Query: 1824 R------PGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADLESP 1877
+ GP+ +PSV K A + +E G+ ES ++ E+
Sbjct: 835 QNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESD------------SEEEAE 882
Query: 1878 TLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEASTPSCP 1937
TLA G Q+ L SP A PP + PS
Sbjct: 883 TLAQVKPSGK-THQIRAALAPAKESPRKGAAPTPPG-----------------KTGPSAA 924
Query: 1938 DPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV 1997
K S SEE+ E+ P A PP + +P S P P
Sbjct: 925 QAGKQDDSGSSSEESDSDGEA--PAAVTSAQVIKPPLIFVDPNRS----PAGPAATPAQA 978
Query: 1998 PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDK-PIASSGTYNLDFDNIELVDTFQTLEPRA 2056
PR S R S S DED P T + + + + + P+A
Sbjct: 979 QAASTPRKARASESTARSSS---SESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKA 1035
Query: 2057 --------------SDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGN 2102
SD K QEG + ++P +T +S S+QA +
Sbjct: 1036 SMAGASSSKESSRISDGKKQEGPATQVDSAVGTLP---ATSPQSTSVQAKGTNKLRKPKL 1092
Query: 2103 PEA--VALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPP---VKETQQEP 2157
PE AP++ S+ S+ + P K T PT + V+ET E
Sbjct: 1093 PEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAES 1152
Query: 2158 DEESLVPSGENLASETKTESAKTEGPSPALLEETPLE--PAVGPKAACPLD--------S 2207
E+ +V ++L S T T S A L+ P+V A D
Sbjct: 1153 SEDDVVAPSQSLLSGYMTPGL-TPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKP 1211
Query: 2208 ESAEGVVPPASGGGRVQN--SPPVGRKTLPLTTAPEA--------------GEVTPSDSG 2251
+ A G++ P +GG + +P RK P+A G+ P +
Sbjct: 1212 QQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEA 1271
Query: 2252 GQEDSPAKGLSVRLEFDYSE--------DKSSWDNQQENPPPTKKIGKKPVAKMPLRRPK 2303
+ S K L+ LE + + + W++++ K G +P A+ P + K
Sbjct: 1272 QVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKR-----KLSGDQPAARTPRSKKK 1326
Query: 2304 MK----------KTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSST 2353
K +PEK T + D+ KG + +
Sbjct: 1327 KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSL--------------GS 1372
Query: 2354 SKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGD 2413
++ P+ Q + D+S K K K E A +A+ D +
Sbjct: 1373 QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSE 1432
Query: 2414 GLNKPAKKKK 2423
++ KKKK
Sbjct: 1433 SPSQKKKKKK 1442
Score = 76.6 bits (187), Expect = 3e-13
Identities = 277/1250 (22%), Positives = 413/1250 (33%), Gaps = 213/1250 (17%)
Query: 251 EAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQ-GEAPPQYLTDD-LEFLR 308
EA A + T A S L P +A + G+ G + P T + L
Sbjct: 93 EAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLL 152
Query: 309 ACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALD 368
+ PR + A P A S+ + V A+ A+ G+ S + + D
Sbjct: 153 SGKSPRKS--AEPSANTTLVSETEEEGSVPAFGAAAKP--GMVSAGQADSSSEDTSSSSD 208
Query: 369 TIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLL---TPTEE--AHPASSLA 423
DV+G P KP QV + + +P P + TP + A P + A
Sbjct: 209 ETDVEGKPSV-----KPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRA 263
Query: 424 SFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPE 483
P + + E GS S E + AG A+++++ + + P
Sbjct: 264 KKPEEESESS--EEGSESEEE-APAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPP 320
Query: 484 GDPGEVP----APSPQERGEHLNTEQS--HEVQPGVPPPPLPKEQSHEVQPGAPPPPLPK 537
G G V A P+E E + E S E P K Q GA P +
Sbjct: 321 GKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKE 380
Query: 538 APSESAR-GPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQG 596
+P + A PPG T PAVAK + GK E
Sbjct: 381 SPRKGAAPAPPG----------KTGPAVAK--------AQAGKRE--------------- 407
Query: 597 EDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADA 656
EDSQ+ S + D E +KPS A S+ + + PRKG A P +T A A
Sbjct: 408 EDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA---PAPPRKTGPAAA 464
Query: 657 SGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWE---GSGLQPKCPDTLQSREGLGRMESF 713
K E+ D E A G Q K T+ G+G +
Sbjct: 465 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM----GMGPLGKG 520
Query: 714 LTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGE-GLLTSPDQPRGPACDASRQ 772
P TP A+V ++ ES+ E S DGE +P Q + +
Sbjct: 521 AGPVPPGKVGPATPSAQVGKWEEDSESSSE-ESSDSSDGEVPTAVAPAQEKSLGNILQAK 579
Query: 773 EFHAGVPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQP 832
+ PPQ A +D + S + E P + +P
Sbjct: 580 PTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDS-----ADSEEAPAAMTAAQAKP 634
Query: 833 SQAQPET-------------SIFDVLKEQAQPPENGKETSP--SHP----GFKDQGADSS 873
+ P+T + V P + G TSP S P G + DSS
Sbjct: 635 ALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS 694
Query: 874 QIHVPVEPQEDNNLPTHGGQEQALGSELQ---------SQLPKGTLSDTP-TSSPTDMVW 923
+E L GQ +++G LQ L +GT P + PT
Sbjct: 695 SSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV 754
Query: 924 ESSLTEESELSAPTRQKLPALGEKRPEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKET 983
++ E+SE S A ++ +P AA + S G S
Sbjct: 755 KAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA---RAPSAKGTIS---- 807
Query: 984 CCTGQGPNKSQQALADALEEGSQHEEACQRHP-GASEAADGCSPLWGLSKR--------- 1033
P K A A A + + R+P ++ A G + + + K
Sbjct: 808 -----APGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQT 862
Query: 1034 --EMASGNTGEAPPCQPDSVALLDAVP------CLPALAPA--SP--GVTPTQDAPETEA 1081
E SG++ E + ++ L P ALAPA SP G PT P
Sbjct: 863 GPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT--PPGKTG 920
Query: 1082 CDETQEGRQQPVPAPQQKMECWATSDAESPKLLAS-------FPSAGEQGGEAGAAETGG 1134
Q G+Q + ++ + SD E+P + S AG A T
Sbjct: 921 PSAAQAGKQDDSGSSSEESD----SDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 976
Query: 1135 SA-GAGDPGKQQAPEKPGEATLSCG----LLQTEHCLTSGEEASTSALRESCQAEHPMAS 1189
A A P K +A E ++ S ++ CLT G + + + P AS
Sbjct: 977 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 1036
Query: 1190 CQDALLPARELGGI--------PRSTMDFST---HQAVPDPKELLLSGPPEVAAPDTPYL 1238
A ++E I P + +D + P + G ++ P P +
Sbjct: 1037 MAGA-SSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEV 1095
Query: 1239 HVDSAAQRGAEDSGVKAVSSADPRAPGE-----------SPCPVGEPPLALENAA----- 1282
+ A ++DS + SS+ GE P P L E AA
Sbjct: 1096 QQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSED 1155
Query: 1283 -----SLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAK 1337
S L +G + P L P + QAS +PK +DS P + LA
Sbjct: 1156 DVVAPSQSLLSGYMTPGLTPANS-------QASKATPK-------LDSSPSVS--STLAA 1199
Query: 1338 GKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQG 1387
G+++A AG + G A+G T + S+ PK+G
Sbjct: 1200 KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTP-------QKSRKPKKG 1242
Score = 74.3 bits (181), Expect = 2e-12
Identities = 246/1169 (21%), Positives = 376/1169 (32%), Gaps = 194/1169 (16%)
Query: 8 SDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSAS 67
S N L A P S + ++ K T S H + L G + S
Sbjct: 107 STNSSVLGADLPSSMKEKAKAET--EKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPS 164
Query: 68 LDPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLA-SPA 126
+ LVS E GA G + S + SSS E EG + PA
Sbjct: 165 ANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSS---DETDVEGKPSVKPA 221
Query: 127 AAPEDGPQT-QSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQK 185
T +SP R+ AP APG + TP + A+P A R ++P+EE +
Sbjct: 222 QVKASSVSTKESPARKAAP-APGKVGDV--------TPQVKGGALPPAKRAKKPEEESES 272
Query: 186 SSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVAS 245
S G ES+E+ AG ++ + +
Sbjct: 273 SE---------------------------------EGSESEEEAPAGTRSQVKASEKILQ 299
Query: 246 VQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTDDLE 305
V+ A +A +GT P K A Q A + + E+ + +D E
Sbjct: 300 VR----AASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEE----DSESSSEESSDSEE 351
Query: 306 FLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKE 365
A + ++V AAS + + P P P G PA+ G +E
Sbjct: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP---APPGKTGPAVAKAQAGKREE 408
Query: 366 ALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLP---VSPEPSLLTPTEEAHPASSL 422
+ + + A +P G P + P+ +P + A PA
Sbjct: 409 DSQSSSEESDSEEE-----------APAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPR 457
Query: 423 ASFP-AAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEH 481
+ P AAQ+ + +E SR S ++ A AA +G QV + G
Sbjct: 458 KTGPAAAQVQVGKQE--EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG 515
Query: 482 PEG------DPGEVPAPSPQ------ERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPG 529
P G PG+V +P E ++E+S + G P + Q +
Sbjct: 516 PLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNI 575
Query: 530 APPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGG 589
P S A+GPP V + P E S DS EEAP
Sbjct: 576 LQAKP----TSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDS-ADSEEAPAAMTA- 629
Query: 590 DPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHS 649
+QA + + P+ K K ++ A ++ P Q PRK G T S
Sbjct: 630 ---------AQAKPALKIPQT-KACPKKTNTTASAKVAPVRVGTQAPRKAGTA-TSPAGS 678
Query: 650 QTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGR 709
A A + P + + G A G GLQ K ++ + LG+
Sbjct: 679 SPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAA-SVPVKGSLGQ 737
Query: 710 MESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPRGPACDA 769
T PT A K ++ ES+ E D E SP Q + +
Sbjct: 738 G----TAPVLPGKTGPTVTQVKAEKQEDSESSEE-----ESDSEEAAASPAQVK-TSVKK 787
Query: 770 SRQEFHAGVPHPPQGENLAADLGLTALILDQDQQGIPS-------CPGEGWI--RGAASE 820
++ + + P + + G Q +Q PS P + RG AS
Sbjct: 788 TQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV 847
Query: 821 WPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSPSHPGFKDQGADSSQIHVPVE 880
+ + +Q PE +E++ E + + P K + QI +
Sbjct: 848 PSVGKAVATAAQAQTGPEED-SGSSEEESDSEEEAETLAQVKPSGK-----THQIRAALA 901
Query: 881 PQEDNNLPTHGGQEQALGSELQSQLPKGTLSDTPTSSPTDMVWESSLTEESELSAPTRQK 940
P +++ P G G S G D+ +SS EES+
Sbjct: 902 PAKES--PRKGAAPTPPGKTGPSAAQAGKQDDSGSSS-----------EESDSDG----- 943
Query: 941 LPALGEKRPEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADA 1000
E + + PP V + S AG + P K++ + + A
Sbjct: 944 ---------EAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTA 994
Query: 1001 LEEGSQHEE-----ACQ---------------RHPGASEAADGCSPLWGLSKREMASGNT 1040
S+ E+ A Q HP + A ++ G
Sbjct: 995 RSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKK 1054
Query: 1041 GEAPPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQQKM 1100
E P Q DS AV LPA +P S V T + R+ +P QQ
Sbjct: 1055 QEGPATQVDS-----AVGTLPATSPQSTSV----------QAKGTNKLRKPKLPEVQQAT 1099
Query: 1101 ECWATSDAESPKLLASFPSAGEQGGEAGA 1129
+ +SD +S S + G GA
Sbjct: 1100 KAPESSDDSEDSSDSSSGSEEDGEGPQGA 1128
Score = 68.2 bits (165), Expect = 1e-10
Identities = 203/962 (21%), Positives = 326/962 (33%), Gaps = 195/962 (20%)
Query: 1529 ERPEGPGAAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEA 1588
E P A PG G Q++ A P E E + + + AP +
Sbjct: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV 291
Query: 1589 VAQDRIPSGKQHQETSACDSPHGEDGPGDF-AHTGVPGHVPRSTCAPSPQREVLTVPEAN 1647
A ++I Q +A G G G A G G V T A P+ + + E +
Sbjct: 292 KASEKIL-----QVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES 346
Query: 1648 SEPWTLDTLGGERRPGVTAGILEMR-----NALGNQSTPAPPTGEVADTPLEPGKVAGAA 1702
S+ E +L+ + + +G S PA + P PGK A
Sbjct: 347 SD--------SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAV 398
Query: 1703 GEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTA 1762
+A+ +++ + S EA P + S KAP + +
Sbjct: 399 AKAQAGKREEDSQSSSEESDSEEEA---------------PAQAKP---SGKAPQVRAAS 440
Query: 1763 ALHGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRES 1822
A +SP + P P R +V V E + + EE +DRE+
Sbjct: 441 APAKESPRKGAA----PAPPRKTGPAAAQVQVGKQEEDSRS--------SSEESDSDREA 488
Query: 1823 PRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPA--------DL 1874
+ P +P+V K S G G + PV + PA P+ D
Sbjct: 489 -LAAMNAAQVKPLGKSPQV--KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDS 545
Query: 1875 ESPTLAAS-SYHGDVVGQV------STDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGD 1927
ES + +S S G+V V S I Q+ P ++ A PP A P
Sbjct: 546 ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQA-KPTSSPAKGPPQKA-------GPVAV 597
Query: 1928 RVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPP 1987
+V+A P D ++ SSDS ++ E P + T +A PA P + P+ +T
Sbjct: 598 QVKAEKPM--DNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTT---- 651
Query: 1988 EEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVD 2047
++ PV G ++ G+ P S P + GT
Sbjct: 652 ----ASAKVAPVRVGTQAPRKAGTATSPAGSS---------PAVAGGT------------ 686
Query: 2048 TFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEAV 2106
+ A D+ + E + K+ +V + ++ ++ + L ++A+ S G A
Sbjct: 687 -----QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP 741
Query: 2107 ALAPDAYSTGSSSASST-LKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPS 2165
L G + + T +K K+ S +++ +++ +P +T + + P+
Sbjct: 742 VL------PGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 795
Query: 2166 GENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQN 2225
S T SA P AA S V PP QN
Sbjct: 796 AARAPSAKGTISA----------------PGKVVTAAAQAKQRSPSKVKPPVR---NPQN 836
Query: 2226 SPPVGRKTLPLTTAPEA-GEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPP 2284
S + R + + +A + +G +EDS + SE++S + + E
Sbjct: 837 STVLARGPASVPSVGKAVATAAQAQTGPEEDSGS-----------SEEESDSEEEAETLA 885
Query: 2285 PTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDD 2344
K GK + L K PR A P P G K DD
Sbjct: 886 QVKPSGKTHQIRAALAPAK-------------ESPRKGAAPTP-PGKTGPSAAQAGKQDD 931
Query: 2345 PNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASA 2404
+ S S E+P + P VDP +++P+ P+ +PA
Sbjct: 932 SGSSSEESDSD-GEAPAAVTSAQVIKPPLI--FVDP----NRSPAGPAATPAQ------- 977
Query: 2405 MEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISA 2464
A+ TP K R +S RS S+ +D PA TP + +
Sbjct: 978 --------------AQAASTPRKA---RASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
Query: 2465 VV 2466
VV
Sbjct: 1021 VV 1022
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 84.3 bits (207), Expect = 2e-15
Identities = 192/806 (23%), Positives = 251/806 (31%), Gaps = 144/806 (17%)
Query: 75 PEVTEPRKDPQGARGPEGSLLPSPPPSQE-------------REHPSSSMPFAECP---- 117
P + + P+G GP G P PP ++ R+ P S+ F P
Sbjct: 836 PRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANG 895
Query: 118 ------------PEGCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQ 165
P G E GP+ + + P N+ GD A P ER + P Q
Sbjct: 896 EKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGP-Q 954
Query: 166 EIAAVPS-------AGRERQPKEEGQK--SSFSFSSGIDQSPGM----SPVPLREPMKAP 212
P G++ P GQ+ + F +G PG+ P PM
Sbjct: 955 GPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPM--- 1011
Query: 213 LCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPA-AAQQGTESSAVLEKSP- 270
GE PG G P + G+A + T P A G + L P
Sbjct: 1012 --GERGHPG---------PPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPG 1060
Query: 271 ------------LKPMAPIPQDPAPRASDRERG-QGEAPPQYLTDDLEFLRACHLPRSNS 317
LK P P P S ERG G A P + P
Sbjct: 1061 DRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGP---------IGIPGRPGPQG 1111
Query: 318 GAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQ 377
P E A ++ Q P G + P GLP PA G G++ D ++ Q
Sbjct: 1112 PPGPAGEKGAPGEKGPQGPAGR--DGLQGPVGLPGPA--GPVGPPGEDG-DKGEIGEPGQ 1166
Query: 378 TGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEP 437
G +G K Q G Q G P PS L + P P
Sbjct: 1167 KGSKGDKGEQGPPGPTGPQGPIG---QPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGP 1223
Query: 438 GSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKG----EHPEGDPGEVPAP- 492
V G+P E D G +G G G + P+G PG + P
Sbjct: 1224 PG----PVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPG 1279
Query: 493 SPQERGEHLNTEQSHEVQPGVPPPPLPK----EQSHEVQPGAPPPPLPKAP--SESARGP 546
+ E+GE E PG PP PK E+ GA PP PK P + +G
Sbjct: 1280 AVGEKGE--PGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGS 1337
Query: 547 PGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKR 606
PGP D P + G PG K + EP G PG KR
Sbjct: 1338 PGPVG---FPGDPGPP--GEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKR 1392
Query: 607 DPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEE 666
P E + PP K G G + G+P +GE+
Sbjct: 1393 GP---PGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQ 1449
Query: 667 DPVLPPVPDGAGEPTVPEGAIWEGSGLQ-PKCPDTLQSREGLGRMESFLTLESEKSDFP- 724
P PDG P P G GL+ P + GL + + EK D
Sbjct: 1450 GLPGSPGPDGPPGPMGPPGL----PGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGL 1505
Query: 725 PTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQG 784
P P PK ++G +T P P GP G+P PP
Sbjct: 1506 PGPQGSSGPKGEQG-----------------ITGPSGPIGPPGP-------PGLPGPPGP 1541
Query: 785 ENLAADLGLTALILDQDQQGIPSCPG 810
+ G T + G P PG
Sbjct: 1542 KGAKGSSGPTGPKGEAGHPGPPGPPG 1567
Score = 59.3 bits (142), Expect = 5e-08
Identities = 152/637 (23%), Positives = 202/637 (31%), Gaps = 98/637 (15%)
Query: 86 GARGPEGSLLPSPP-----PSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRR 140
G GP G + P P P ER HP P E G + GP P +
Sbjct: 991 GPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGP-AGLPGK 1049
Query: 141 EPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGM 200
+ P G FP +R P + A+ G E P G S G + G
Sbjct: 1050 DGPPGLRG-----FPGDRGLPGP---VGALGLKGNEGPPGPPGPAGSPG-ERGPAGAAGP 1100
Query: 201 SPVPLREPMKAPL--CGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTP-------E 251
+P R + P GE PG Q G G A P E
Sbjct: 1101 IGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGE 1160
Query: 252 APAAAQQGTESSAVLE--KSPLKPMAPIPQDPAPRASDRERG----------QGEAPPQY 299
Q+G++ + P P PI Q P P +D E G +G+ P+
Sbjct: 1161 IGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ-PGPSGADGEPGPRGQQGLFGQKGDEGPRG 1219
Query: 300 LTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVG-AYLPHAELPWGLP----SPA 354
+ LP +V P G + P A+ P G P +P
Sbjct: 1220 FPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPG 1279
Query: 355 LVPEAGGSGKEALDTIDVQGHPQ--TGMRGTKPNQVVCVAAG-----GQPEGGLPVSPEP 407
V E G G+ + +G P G RG K AAG G P P
Sbjct: 1280 AVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPG 1339
Query: 408 SLLTPTEEAHPASSLASFPAAQIPIAVE-----EPGSSSRESVSKAGMPVSADAAKEVVD 462
+ P + P PA Q + EPG + S G P + +
Sbjct: 1340 PVGFPGDPGPPGEP---GPAGQDGPPGDKGDDGEPGQTG--SPGPTGEPGPSGPPGKRGP 1394
Query: 463 AGLVGLERQVSDLGSKGEHP-EGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPP---- 517
G G E + + G+KGE EG PG+ PQ PG P P
Sbjct: 1395 PGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGA-------------PGKPGPDGLRG 1441
Query: 518 LPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPG 577
+P + PG+P P P P GPPG G K G + PG
Sbjct: 1442 IPGPVGEQGLPGSPGPDGPPGPM----GPPG-LPGLK----------GDSGPKGEKGHPG 1486
Query: 578 GKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPR 637
P + G+ G+ Q S + G+ ++ PS P PP
Sbjct: 1487 LIGLIGPPGEQGEKGDRGLPGPQGSSGPK----GEQGITGPSGPIGPPGPPGLPG--PPG 1540
Query: 638 KGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVP 674
GA + GP EA G P G V+ P+P
Sbjct: 1541 PKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLP 1577
Score = 58.9 bits (141), Expect = 7e-08
Identities = 163/744 (21%), Positives = 233/744 (31%), Gaps = 163/744 (21%)
Query: 464 GLVGLERQVSDLGSKGEHPE-------GDPGEVPAPSPQERGEHLNTEQSHEVQPGVP-- 514
G+ G++ Q G+ G E G+PG P PQ E+ +PG+P
Sbjct: 697 GVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPG-EKGPLGKPGLPGM 755
Query: 515 -----PPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGP--------------TDGAKV 555
PP P ++ + G PP P+ P G PGP T G K
Sbjct: 756 PGADGPPGHPGKEGPPGEKGGQGPPGPQGPI----GYPGPRGVKGADGIRGLKGTKGEKG 811
Query: 556 HED--STSPAVAKEGSRSPGDSPGGK-EEAPEPPDG-----GDPGNL--QGEDSQ----- 600
+ + +G R PG + E+ PE P G GDPG L GE +
Sbjct: 812 EDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPG 871
Query: 601 --AFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASG 658
+ ++ P+ P ++ E + +P +G G T GP + +G
Sbjct: 872 LPGYPGRQGPKGSIGFPGFPGANGEKGGRGTP--GKPGPRGQRGPT-GPRGERGPRGITG 928
Query: 659 LPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQ-PKCPDTLQSREGL-GRMESFLTL 716
P G P P G P P+G +G PK P ++GL G
Sbjct: 929 KPGPKGNSGGDGPAGPPGERGPNGPQGP----TGFPGPKGPPGPPGKDGLPGHPGQRGET 984
Query: 717 ESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFHA 776
+ PP P V P+ GE T P RG H
Sbjct: 985 GFQGKTGPPGPPGVVGPQGPTGE-----------------TGPMGERG----------HP 1017
Query: 777 GVPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQ 836
G P PP + L G D G+P G +RG + L L
Sbjct: 1018 GPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALG----- 1072
Query: 837 PETSIFDVLKEQAQPPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQA 896
LK PP G PG + + I +P P P G++ A
Sbjct: 1073 --------LKGNEGPP--GPPGPAGSPGERGPAGAAGPIGIPGRPGPQGP-PGPAGEKGA 1121
Query: 897 LGSELQSQLPKGTLSDTPTSSPTDMVWESSLT-------EESELSAPTRQKLPA-LGEKR 948
G + P+G P + + ++ E+ P ++ GE+
Sbjct: 1122 PGEKG----PQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQG 1177
Query: 949 PEGACG-DGQSSRVSPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQH 1007
P G G G + P AD G+ + QQ L G +
Sbjct: 1178 PPGPTGPQGPIGQPGPSGAD-------------------GEPGPRGQQGLF-----GQKG 1213
Query: 1008 EEACQRHPGASEAADGCSPLWGLSKREMASGNTGEAPPCQPDSVALLDAVPCLPALAPAS 1067
+E + PG G L G + +G+ G+ P P P
Sbjct: 1214 DEGPRGFPGPPGPV-GLQGLPGPPGEKGETGDVGQMGPPGPPG--------------PRG 1258
Query: 1068 PGVTPTQDAPETEACDETQEGRQQPVPAPQQKMECWATSDAESPKLLASFPSAGEQGGEA 1127
P P D P+ G + P E +A P L G +G
Sbjct: 1259 PSGAPGADGPQ---------GPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERG 1309
Query: 1128 GAAETGGSAGAGDPGKQQAPEKPG 1151
E+G S AG PG + P G
Sbjct: 1310 EKGESGPSGAAGPPGPKGPPGDDG 1333
Score = 57.0 bits (136), Expect = 3e-07
Identities = 263/1127 (23%), Positives = 350/1127 (31%), Gaps = 220/1127 (19%)
Query: 437 PGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHP-EGDPGEVPAPSPQ 495
P S++ES ++A + + A + AG +GL + +G G +G+PG+V P+
Sbjct: 537 PMVSAQESQAQAILQQARLALRG--PAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPR 594
Query: 496 ERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKV 555
GV PP P P +A S+ ARG PG T G K
Sbjct: 595 ----------------GVQGPP---------GPAGKPGRRGRAGSDGARGMPGQT-GPKG 628
Query: 556 HE--DSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKD 613
D + ++G R GD G P PP GD G +G+D + E G
Sbjct: 629 DRGFDGLAGLPGEKGHR--GDP--GPSGPPGPP--GDDGE-RGDDGEVGPRGLPGEPGPR 681
Query: 614 ELSKPSSDAESRDHP--SSHSAQPPRKGGAG--HTDGPHSQTAEADASGLPHKL------ 663
L P P + QP KG G GP Q A GLP
Sbjct: 682 GLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPP 741
Query: 664 GEEDPV----LPPVPDGAGEPTVP--EGAIWEGSGLQPKCPD---TLQSREGLGRMESFL 714
GE+ P+ LP +P G P P EG E G P P G+ +
Sbjct: 742 GEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIR 801
Query: 715 TLESEKSD-----FP--------PTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQ 761
L+ K + FP E+ P GE E K G G
Sbjct: 802 GLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPK-----GRGGPNGDPG 856
Query: 762 PRGPACDASRQEFHAGVPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEW 821
P GP + + G+P P + +G ++G PG+ RG
Sbjct: 857 PLGPPGEKGKLGV-PGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPT 915
Query: 822 PLLSSEKHLQPSQAQPETSIFDVLKEQAQPP----ENGKETSPSHPGFKDQGADSSQIHV 877
E+ + +P A PP NG + PG K
Sbjct: 916 G-PRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKG---------- 964
Query: 878 PVEPQEDNNLPTHGGQEQALGSELQS--QLPKGTLSDTPTSSPTDMVWESSLTEESELSA 935
P P + LP H GQ G + ++ P G + + T + E
Sbjct: 965 PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERG--HPGPPGP 1022
Query: 936 PTRQKLPALGEKRPEGACGD----GQSSRVSPPAADVLKDFSLAGNFSRKETCCTGQGPN 991
P Q LP L K EG GD G + PP L+ F +G
Sbjct: 1023 PGEQGLPGLAGK--EGTKGDPGPAGLPGKDGPPG---LRGFP------------GDRGLP 1065
Query: 992 KSQQALADALEEGSQHEEACQRHPGASEAADGCSPLW-----------GLSKREMASGNT 1040
AL EG PG A P+ G + + A G
Sbjct: 1066 GPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEK 1125
Query: 1041 GEAPPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGR-----QQPVPA 1095
G P D + +P PA P P +D + E + Q+G +Q P
Sbjct: 1126 GPQGPAGRDGLQGPVGLP-----GPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPG 1180
Query: 1096 PQQKMECWATSDAESPKLLASFPSAGEQGGEAGAAETGGSAG-AGDPGKQQAPEKPGEAT 1154
P P+ P GE G G G GD G + P PG
Sbjct: 1181 P------------TGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVG 1228
Query: 1155 LSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDALLPARELGGIPRSTMDFSTHQ 1214
L GL GE+ T + + P A G P +
Sbjct: 1229 LQ-GLPG-----PPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVG 1282
Query: 1215 AVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRG--AEDSGVKAVSSADPRAPGESPCPVG 1272
+P E G P P P +RG E A P+ P P G
Sbjct: 1283 EKGEPGEAGEPGLPGEGGPPGP------KGERGEKGESGPSGAAGPPGPKGPPGDDGPKG 1336
Query: 1273 EP-PLALENAASLKLFAGSLAPLLQPGAAGGE-IPAVQASSGSPKARTTEGPV----DSM 1326
P P+ F G P +PG AG + P + G P + GP S
Sbjct: 1337 SPGPVG---------FPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSG 1387
Query: 1327 PCLDRMPLLAKGKQATGEEKAA------------TAP----GAGAKASGEGMAG--DAAG 1368
P R P G + EK A T P GA K +G+ G G
Sbjct: 1388 PPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVG 1447
Query: 1369 E--------TEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEKPV 1420
E +G MG P +G SG G P I E+
Sbjct: 1448 EQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEK--------GHPGLIGLIGPPGEQGE 1499
Query: 1421 LGALATPGEKAGAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPP 1467
G PG + +G + +T P GP GPPG LP PP
Sbjct: 1500 KGDRGLPGPQGSSGPKG-EQGITGPSGPIG-PPGPPG-----LPGPP 1539
Score = 53.5 bits (127), Expect = 3e-06
Identities = 182/741 (24%), Positives = 231/741 (31%), Gaps = 119/741 (16%)
Query: 1297 PGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQA----TGEEKAATAPG 1352
PGA G + + + G P R GP P +R P GK +G + A PG
Sbjct: 891 PGANGEK--GGRGTPGKPGPRGQRGPTG--PRGERGPRGITGKPGPKGNSGGDGPAGPPG 946
Query: 1353 AGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIAT-LTGFPDFREH 1411
+G G G G P +D G G + Q T G P
Sbjct: 947 ERGPNGPQGPTG-----FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGP 1001
Query: 1412 IAKIFEKPVLGALATPGEKAGAGRSAV----GKDLTR-PLGPEKL--LDGPPGV----DV 1460
E +G PG G + GK+ T+ GP L DGPPG+
Sbjct: 1002 QGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGD 1061
Query: 1461 TLLPAPPARLQVEKKQQLAGEAEISHLALQDPASDKLLGPAGLTWERNLPGAGVGKEMAG 1520
LP P L ++ + G GPAG ER GA + G
Sbjct: 1062 RGLPGPVGALGLKGNEGPPGPP----------------GPAGSPGERGPAGAAGPIGIPG 1105
Query: 1521 VPPTLREDERPEGPGAAWPGLEGQAYSQLERSRQELAS--GLPSPAATQELPVERAAAFQ 1578
P + P GP A G G+ Q R L GLP PA P E +
Sbjct: 1106 RPGP----QGPPGP-AGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGE 1160
Query: 1579 VA-PHSHGEEAVAQDRIPSGKQH-QETSACDSPHGEDG-PGDFAHTGVPGHV----PRST 1631
+ P G + ++ P G Q P G DG PG G+ G PR
Sbjct: 1161 IGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGF 1220
Query: 1632 CAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGEVADT 1691
P + +P E +G PG G A G PP G
Sbjct: 1221 PGPPGPVGLQGLPGPPGEKGETGDVGQMGPPG-PPGPRGPSGAPGADGPQGPPGGIG--- 1276
Query: 1692 PLEPGKVA--GAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDP 1749
PG V G GEA G+ L G+ E G + S AG P + P
Sbjct: 1277 --NPGAVGEKGEPGEA-GEPGLPGEGGPPGPKGERGEKGESGP-SGAAG----PPGPKGP 1328
Query: 1750 ACSDKAPGMEGTAALHGDS--PARPQQAKEQ-----------------PGPE-RPIPAGD 1789
D G G GD P P A + PGP P P+G
Sbjct: 1329 PGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGP 1388
Query: 1790 -GKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSD 1848
GK PP P + + A E + + GP P K P + +
Sbjct: 1389 PGK---RGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGP 1445
Query: 1849 ETRGAEGTESSPVADDIIQPAAPADLESPTLAASSY------HGDVVGQVSTDLIAQSIS 1902
G +G SP D P P L P L S H ++G +
Sbjct: 1446 V--GEQGLPGSPGPDGPPGPMGPPGL--PGLKGDSGPKGEKGHPGLIGLIGPP----GEQ 1497
Query: 1903 PAAAHAGLP-------PSAAEHIVSPSAPAGDRVEASTPSCPDPAKDLSRSSDSEEAFET 1955
GLP P + I PS P G P P P + +
Sbjct: 1498 GEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGP-----KGAKGSSGPTG 1552
Query: 1956 PESTTPVKAPPAPPPPPPEVI 1976
P+ PP PP PP EVI
Sbjct: 1553 PKGEAGHPGPPGPPGPPGEVI 1573
Score = 48.9 bits (115), Expect = 7e-05
Identities = 325/1427 (22%), Positives = 422/1427 (29%), Gaps = 227/1427 (15%)
Query: 480 EHPEGDPGEVPAPS--PQERGEHLNTEQSHEVQP----GVPPPPLPKEQSHEVQPGAPPP 533
E PE D G+ P PS P E + TE E+ P P P + E G
Sbjct: 281 EDPE-DLGKEPTPSKKPVEAAKE-TTEVPEELTPTPTEAAPMPETSEGAGKEEDVGIGD- 337
Query: 534 PLPKAPSESARGPPGPTD-----GAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDG 588
PSE P D G + + T P E S D+ AP P +G
Sbjct: 338 -YDYVPSEDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEG 396
Query: 589 GDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPH 648
D +L+GE ++ D E D P+S + S P + Q G G G
Sbjct: 397 AD--DLEGEFTEETIRNLD-ENYYDPYYDPTS-SPSEIGPGMPANQDTIYEGIGGPRGEK 452
Query: 649 SQTAEAD-------ASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWE-GSGLQPKCP-- 698
Q E G P G E P P P G PT G E G +P P
Sbjct: 453 GQKGEPAIIEPGMLIEGPP---GPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGA 509
Query: 699 DTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTS 758
D L G M F + V+ +AQ + G GL
Sbjct: 510 DGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGR 569
Query: 759 PDQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAA 818
P P + E P P+G QG P G+ RG A
Sbjct: 570 PGPVGPPGSGGLKGEPGDVGPQGPRG-----------------VQGPPGPAGKPGRRGRA 612
Query: 819 SEWPLLSSEKHLQPSQAQPETSI-FDVLK----EQAQPPENGKETSPSHPGFKDQGADSS 873
S P Q P+ FD L E+ + G P PG + D
Sbjct: 613 G-----SDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDG 667
Query: 874 QIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTLSDTPTSSPTDMVWE----SSLTE 929
++ LP G LG PKG T M + ++
Sbjct: 668 EV-------GPRGLPGEPGPRGLLG-------PKGPPGPPGPPGVTGMDGQPGPKGNVGP 713
Query: 930 ESELSAPTRQKLP-ALGEKRPEGACG-DGQSSRVSPPAADVLKDFSLAGNFSRKETC--- 984
+ E P +Q P A G P+GA G G+ + P + KE
Sbjct: 714 QGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGE 773
Query: 985 CTGQGPNKSQQALADALEEGSQHEEACQRHPGASEAADGCSPLWGLSKREMASGNTGEAP 1044
GQGP Q + G + + + G ++ G G G+ GE
Sbjct: 774 KGGQGPPGPQGPIGYPGPRGVKGADGIRGLKG-TKGEKGEDGFPGFKGDMGIKGDRGEIG 832
Query: 1045 PCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQQKMECWA 1104
P P +D PE G P+ P +K +
Sbjct: 833 PPGPRG-----------------------EDGPEGPKGRGGPNGDPGPLGPPGEKGKLGV 869
Query: 1105 TS-----DAESPKLLASFPSAGEQGGEAGAAETGGSAG----------AGDPGKQQAPEK 1149
+ PK FP GE G T G G G+ G + K
Sbjct: 870 PGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGK 929
Query: 1150 PGEATLSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDALLPARELGGIP--RST 1207
PG S G G P +D L G P R
Sbjct: 930 PGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDG------LPGHPGQRGE 983
Query: 1208 MDFSTHQAVPDPKELL-LSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGE 1266
F P P ++ GP P H G + A PG
Sbjct: 984 TGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGP 1043
Query: 1267 SPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTEGP---- 1322
+ P + P L + G + L G G P +GSP R G
Sbjct: 1044 AGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGP--PGPPGPAGSPGERGPAGAAGPI 1101
Query: 1323 -VDSMPCLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAA-----GETEGSMER 1376
+ P P A K A GE+ G G+ G A GE +G
Sbjct: 1102 GIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGE-DGDKGE 1160
Query: 1377 MGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGEKAGAGRS 1436
+GEP Q +G G EQ G P I + GA PG + G
Sbjct: 1161 IGEPGQKGSKGDKG------EQ-----GPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLF 1209
Query: 1437 AVGKDLTRPLGPEKLLDGPPG-VDVTLLPAPPARLQVEKKQQLAGEAEISHLALQDPASD 1495
D GP + GPPG V + LP PP + E + P
Sbjct: 1210 GQKGD----EGP-RGFPGPPGPVGLQGLPGPPGE-----------KGETGDVGQMGPP-- 1251
Query: 1496 KLLGPAGLTWERNLPGA-GVGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQLER-SR 1553
GP G PGA G G+ E+ E A PGL G+ + R
Sbjct: 1252 ---GPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGER 1308
Query: 1554 QELASGLPSPAATQELPVERAAAFQVAPH-SHGEEAVAQDRIPSGKQHQETSACDSPHGE 1612
E PS AA P + P S G D P G+ P G+
Sbjct: 1309 GEKGESGPSGAAGP--PGPKGPPGDDGPKGSPGPVGFPGDPGPPGE--------PGPAGQ 1358
Query: 1613 DG-PGDFAHTGVPGHV--PRSTCAPSP------------------QREVLTVPEANSE-- 1649
DG PGD G PG P T P P Q E EA E
Sbjct: 1359 DGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGP 1418
Query: 1650 PWTLDTLGGERRPGVTA--GILEMRNALGNQSTPAPPTGEVADTPLEPGKVAGAAGEA-- 1705
P +G + PG G+ + +G Q P P + P+ P + G G++
Sbjct: 1419 PGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGP 1478
Query: 1706 ------EGDITLSTAETQACASGDLPEAGTTRTFSVVAGD--LVLPGSCQDPACSDKAPG 1757
G I L + GD G + S G+ + P P PG
Sbjct: 1479 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS-SGPKGEQGITGPSGPIGPPGPPGLPG 1537
Query: 1758 MEGTAALHGDS-PARPQQAKEQPGPERPIPAGDGKVCVSSPPEPDET 1803
G G S P P+ PGP P P G+V P + T
Sbjct: 1538 PPGPKGAKGSSGPTGPKGEAGHPGPPGP-PGPPGEVIQPLPIQASRT 1583
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 83.6 bits (205), Expect = 3e-15
Identities = 269/1331 (20%), Positives = 434/1331 (32%), Gaps = 235/1331 (17%)
Query: 1247 GAEDSGVKAVSSADPRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPA 1306
G DS + SS+ E V + + ++ + A AP PG G P
Sbjct: 194 GQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPA--PGKVGDVTPQ 251
Query: 1307 VQASSGSPKART------TEGPVDSMPCLDRMPLLAKGKQATGEE----KAATAPGAGAK 1356
V+ + P R +E + + P + + E+ +AA+AP G
Sbjct: 252 VKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTP 311
Query: 1357 ASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGGVDTSSE--------QIATLTGFPDF 1408
G A S + G+P +D + + D+ E Q
Sbjct: 312 GKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQV 371
Query: 1409 REHIAKIFEKPVLGALATPGEKAG--AGRSAVGK-------------------DLTRPLG 1447
A E P GA P K G ++ GK +P G
Sbjct: 372 GAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSG 431
Query: 1448 --PEKLLDGPPGVDVT---LLPAPP-------ARLQVEKKQQLA------GEAEISHLAL 1489
P+ P + PAPP A++QV K+++ + +++ LA
Sbjct: 432 KAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAA 491
Query: 1490 QDPASDKLLGPAGLTWERNLPGAG-VGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQ 1548
+ A K LG + + G G +GK VPP P W E + S
Sbjct: 492 MNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKW---EEDSESS 548
Query: 1549 LERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSGKQHQETSACDS 1608
E S +P+ A + Q P S + Q P Q + D+
Sbjct: 549 SEESSDSSDGEVPTAVAPAQ-EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDN 607
Query: 1609 PHGEDGPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAGI 1668
+ D A + P + A + + L +P+ + P +T + V G
Sbjct: 608 SESSEESSDSADS---EEAPAAMTA-AQAKPALKIPQTKACPKKTNTTASAKVAPVRVGT 663
Query: 1669 LEMRNALGNQSTPAPPTGEVADTPLEPGKVAGAAGEAEGD-----ITLSTAETQACASGD 1723
R A G ++PA + VA P + + ++ E++ + + ++ + ++ G
Sbjct: 664 QAPRKA-GTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL 722
Query: 1724 LPEAGTTRTFSVVAGDL------VLPGSCQDPACSDKAPGMEGTAALHGDSPA------- 1770
+A + V G L VLPG KA E + + +S +
Sbjct: 723 QVKAASV----PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 778
Query: 1771 -------RPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESP 1823
+ QAK P R P+ G + S P T + + +P ++ +P
Sbjct: 779 AQVKTSVKKTQAKANPAAAR-APSAKGTI---SAPGKVVTAAAQAKQRSPSKVKPPVRNP 834
Query: 1824 R------PGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADLESP 1877
+ GP+ +PSV K A + +E G+ ES ++ E+
Sbjct: 835 QNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESD------------SEEEAE 882
Query: 1878 TLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEASTPSCP 1937
TLA G Q+ L SP A PP + PS
Sbjct: 883 TLAQVKPSGK-THQIRAALAPAKESPRKGAAPTPPG-----------------KTGPSAA 924
Query: 1938 DPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV 1997
K S SEE+ E+ P A PP + +P S P P
Sbjct: 925 QAGKQDDSGSSSEESDSDGEA--PAAVTSAQVIKPPLIFVDPNRS----PAGPAATPAQA 978
Query: 1998 PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDK-PIASSGTYNLDFDNIELVDTFQTLEPRA 2056
PR S R S S DED P T + + + + + P+A
Sbjct: 979 QAASTPRKARASESTARSSS---SESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKA 1035
Query: 2057 --------------SDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGN 2102
SD K QEG + ++P +T +S S+QA +
Sbjct: 1036 SMAGASSSKESSRISDGKKQEGPATQVDSAVGTLP---ATSPQSTSVQAKGTNKLRKPKL 1092
Query: 2103 PEA--VALAPDAY-STGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPP---VKETQQE 2156
PE AP++ + SS SS+ P K T PT + V+ET E
Sbjct: 1093 PEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAE 1152
Query: 2157 PDEESLVPSGENLASETKTESAKTEGPSPALLEETPLE--PAVGPKAACPLD-------- 2206
E+ +V ++L S T T S A L+ P+V A D
Sbjct: 1153 SSEDDVVAPSQSLLSGYMTPGL-TPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAK 1211
Query: 2207 SESAEGVVPPASGGGRVQN--SPPVGRKTLPLTTAPEA--------------GEVTPSDS 2250
+ A G++ P +GG + +P RK P+A G+ P +
Sbjct: 1212 PQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNE 1271
Query: 2251 GGQEDSPAKGLSVRLEFDYSE--------DKSSWDNQQENPPPTKKIGKKPVAKMPLRRP 2302
+ S K L+ LE + + + W++++ K G +P A+ P +
Sbjct: 1272 AQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKR-----KLSGDQPAARTPRSKK 1326
Query: 2303 KMK----------KTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSS 2352
K K +PEK T + D+ KG +
Sbjct: 1327 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSL--------------G 1372
Query: 2353 TSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDG 2412
+ ++ P+ Q + D+S K K K E A +A+ D
Sbjct: 1373 SQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDS 1432
Query: 2413 DGLNKPAKKKK 2423
+ ++ KKKK
Sbjct: 1433 ESPSQKKKKKK 1443
Score = 78.6 bits (192), Expect = 9e-14
Identities = 301/1443 (20%), Positives = 471/1443 (32%), Gaps = 252/1443 (17%)
Query: 8 SDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSAS 67
S N L A P S + ++ K T S H + L G + S
Sbjct: 107 STNSSVLGADLPSSMKEKAKAET--EKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPS 164
Query: 68 LDPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLA-SPA 126
+ LVS E GA G + S + SSS E EG + PA
Sbjct: 165 ANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSS---DETDVEGKPSVKPA 221
Query: 127 AAPEDGPQT-QSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQK 185
T +SP R+ AP APG + TP + A+P A R ++P+EE +
Sbjct: 222 QVKASSVSTKESPARKAAP-APGKVGDV--------TPQVKGGALPPAKRAKKPEEESES 272
Query: 186 SSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVAS 245
S G ES+E+ AG ++ + +
Sbjct: 273 SE---------------------------------EGSESEEEAPAGTRSQVKASEKILQ 299
Query: 246 VQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTDDLE 305
V+ A +A +GT P K A Q A + + E+ + +D E
Sbjct: 300 VR----AASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEE----DSESSSEESSDSEE 351
Query: 306 FLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKE 365
A + ++V AAS + + P P P G PA+ G +E
Sbjct: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP---APPGKTGPAVAKAQAGKREE 408
Query: 366 ALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLP---VSPEPSLLTPTEEAHPASSL 422
+ + + A +P G P + P+ +P + A PA
Sbjct: 409 DSQSSSEESDSEEE-----------APAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPR 457
Query: 423 ASFP-AAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEH 481
+ P AAQ+ + +E SR S ++ A AA +G QV + G
Sbjct: 458 KTGPAAAQVQVGKQE--EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG 515
Query: 482 PEG------DPGEVPAPSPQ------ERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPG 529
P G PG+V +P E ++E+S + G P + Q +
Sbjct: 516 PLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNI 575
Query: 530 APPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGG 589
P S A+GPP V + P E S DS EEAP
Sbjct: 576 LQAKP----TSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDS-ADSEEAPAAMTA- 629
Query: 590 DPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHS 649
+QA + + P+ K K ++ A ++ P Q PRK G T S
Sbjct: 630 ---------AQAKPALKIPQT-KACPKKTNTTASAKVAPVRVGTQAPRKAGTA-TSPAGS 678
Query: 650 QTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGR 709
A A + P + + G A G GLQ K ++ + LG+
Sbjct: 679 SPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAA-SVPVKGSLGQ 737
Query: 710 MESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPRGPACDA 769
T PT A K ++ ES+ E D E SP Q + +
Sbjct: 738 G----TAPVLPGKTGPTVTQVKAEKQEDSESSEE-----ESDSEEAAASPAQVK-TSVKK 787
Query: 770 SRQEFHAGVPHPPQGENLAADLGLTALILDQDQQGIPS-------CPGEGWI--RGAASE 820
++ + + P + + G Q +Q PS P + RG AS
Sbjct: 788 TQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV 847
Query: 821 WPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSPSHPGFKDQGADSSQIHVPVE 880
+ + +Q PE +E++ E + + P K + QI +
Sbjct: 848 PSVGKAVATAAQAQTGPEED-SGSSEEESDSEEEAETLAQVKPSGK-----THQIRAALA 901
Query: 881 PQEDNNLPTHGGQEQALGSELQSQLPKGTLSDTPTSSPTDMVWESSLTEESELSAPTRQK 940
P +++ P G G S G D+ +SS EES+
Sbjct: 902 PAKES--PRKGAAPTPPGKTGPSAAQAGKQDDSGSSS-----------EESDSDG----- 943
Query: 941 LPALGEKRPEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADA 1000
E + + PP V + S AG + P K++ + + A
Sbjct: 944 ---------EAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTA 994
Query: 1001 LEEGSQHEE-----ACQ---------------RHPGASEAADGCSPLWGLSKREMASGNT 1040
S+ E+ A Q HP + A ++ G
Sbjct: 995 RSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKK 1054
Query: 1041 GEAPPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQQKM 1100
E P Q DS AV LPA +P S V T + R+ +P QQ
Sbjct: 1055 QEGPATQVDS-----AVGTLPATSPQSTSV----------QAKGTNKLRKPKLPEVQQAT 1099
Query: 1101 ECWATSDAESPKLLASFPSAGEQGGEAGAAETGGSAGAGDPGKQQAPEKPGEATLSCGLL 1160
+ +SD +S S E+ GE G GA
Sbjct: 1100 KAPESSDDSEDSSDSS--SGSEEDGE-------GPQGA---------------------- 1128
Query: 1161 QTEHCLTSGEEASTSALRESCQAEHPMASCQDALLPAREL--GGIPRSTMDFSTHQAVPD 1218
++ H L + T L E AE +S D + P++ L G + ++ +
Sbjct: 1129 KSAHTLVGPTPSRTETLVEETAAE---SSEDDVVAPSQSLLSGYMTPGLTPANSQASKAT 1185
Query: 1219 PKELLLSGPPEV----AAPDTPYLHVDSAAQRGA-----EDSGVKAVSSADPRAPGESPC 1269
PK L P V AA D P ++ Q+ A + G +A S P+ +
Sbjct: 1186 PK---LDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKK 1242
Query: 1270 PVGEP---PLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSM 1326
G P LAL++ + + G PL + + + + + VD+
Sbjct: 1243 GAGNPQASTLALQSNIT-QCLLGQPWPLNEAQVQASVVKVLTELLEQERKKV----VDTT 1297
Query: 1327 PCLDRMPLLAKGKQATGEEKAATAPGAGAKAS-GEGMAGDAAGETE-GSMERMGEPSQDP 1384
R ++ ++ +G++ AA P + K G G G+A+ E S G+ +D
Sbjct: 1298 KESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDK 1357
Query: 1385 KQG 1387
G
Sbjct: 1358 ASG 1360
Score = 77.0 bits (188), Expect = 3e-13
Identities = 277/1251 (22%), Positives = 413/1251 (33%), Gaps = 214/1251 (17%)
Query: 251 EAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQ-GEAPPQYLTDD-LEFLR 308
EA A + T A S L P +A + G+ G + P T + L
Sbjct: 93 EAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLL 152
Query: 309 ACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALD 368
+ PR + A P A S+ + V A+ A+ G+ S + + D
Sbjct: 153 SGKSPRKS--AEPSANTTLVSETEEEGSVPAFGAAAKP--GMVSAGQADSSSEDTSSSSD 208
Query: 369 TIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLL---TPTEE--AHPASSLA 423
DV+G P KP QV + + +P P + TP + A P + A
Sbjct: 209 ETDVEGKPSV-----KPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRA 263
Query: 424 SFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPE 483
P + + E GS S E + AG A+++++ + + P
Sbjct: 264 KKPEEESESS--EEGSESEEE-APAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPP 320
Query: 484 GDPGEVP----APSPQERGEHLNTEQS--HEVQPGVPPPPLPKEQSHEVQPGAPPPPLPK 537
G G V A P+E E + E S E P K Q GA P +
Sbjct: 321 GKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKE 380
Query: 538 APSESAR-GPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQG 596
+P + A PPG T PAVAK + GK E
Sbjct: 381 SPRKGAAPAPPG----------KTGPAVAK--------AQAGKRE--------------- 407
Query: 597 EDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADA 656
EDSQ+ S + D E +KPS A S+ + + PRKG A P +T A A
Sbjct: 408 EDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA---PAPPRKTGPAAA 464
Query: 657 SGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWE---GSGLQPKCPDTLQSREGLGRMESF 713
K E+ D E A G Q K T+ G+G +
Sbjct: 465 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM----GMGPLGKG 520
Query: 714 LTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGE-GLLTSPDQPRGPACDASRQ 772
P TP A+V ++ ES+ E S DGE +P Q + +
Sbjct: 521 AGPVPPGKVGPATPSAQVGKWEEDSESSSE-ESSDSSDGEVPTAVAPAQEKSLGNILQAK 579
Query: 773 EFHAGVPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQP 832
+ PPQ A +D + S + E P + +P
Sbjct: 580 PTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDS-----ADSEEAPAAMTAAQAKP 634
Query: 833 SQAQPET-------------SIFDVLKEQAQPPENGKETSP--SHP----GFKDQGADSS 873
+ P+T + V P + G TSP S P G + DSS
Sbjct: 635 ALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS 694
Query: 874 QIHVPVEPQEDNNLPTHGGQEQALGSELQ---------SQLPKGTLSDTP-TSSPTDMVW 923
+E L GQ +++G LQ L +GT P + PT
Sbjct: 695 SSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV 754
Query: 924 ESSLTEESELSAPTRQKLPALGEKRPEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKET 983
++ E+SE S A ++ +P AA + S G S
Sbjct: 755 KAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA---RAPSAKGTIS---- 807
Query: 984 CCTGQGPNKSQQALADALEEGSQHEEACQRHP-GASEAADGCSPLWGLSKR--------- 1033
P K A A A + + R+P ++ A G + + + K
Sbjct: 808 -----APGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQT 862
Query: 1034 --EMASGNTGEAPPCQPDSVALLDAVP------CLPALAPA--SP--GVTPTQDAPETEA 1081
E SG++ E + ++ L P ALAPA SP G PT P
Sbjct: 863 GPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT--PPGKTG 920
Query: 1082 CDETQEGRQQPVPAPQQKMECWATSDAESPKLLAS-------FPSAGEQGGEAGAAETGG 1134
Q G+Q + ++ + SD E+P + S AG A T
Sbjct: 921 PSAAQAGKQDDSGSSSEESD----SDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 976
Query: 1135 SA-GAGDPGKQQAPEKPGEATLSCG----LLQTEHCLTSGEEASTSALRESCQAEHPMAS 1189
A A P K +A E ++ S ++ CLT G + + + P AS
Sbjct: 977 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 1036
Query: 1190 CQDALLPARELGGI--------PRSTMDFST---HQAVPDPKELLLSGPPEVAAPDTPYL 1238
A ++E I P + +D + P + G ++ P P +
Sbjct: 1037 MAGA-SSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEV 1095
Query: 1239 HVDSAAQRGAEDSGVKAVSSADPRAPGESP-------CPVGEPPLALEN----------- 1280
+ A ++DS + SS+ GE P VG P E
Sbjct: 1096 QQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSE 1155
Query: 1281 ----AASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMPLLA 1336
A S L +G + P L P + QAS +PK +DS P + LA
Sbjct: 1156 DDVVAPSQSLLSGYMTPGLTPANS-------QASKATPK-------LDSSPSVS--STLA 1199
Query: 1337 KGKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQG 1387
G+++A AG + G A+G T + S+ PK+G
Sbjct: 1200 AKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTP-------QKSRKPKKG 1243
Score = 70.1 bits (170), Expect = 3e-11
Identities = 225/1144 (19%), Positives = 374/1144 (32%), Gaps = 141/1144 (12%)
Query: 1529 ERPEGPGAAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEA 1588
E P A PG G Q++ A P E E + + + AP +
Sbjct: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV 291
Query: 1589 VAQDRIPSGKQHQETSACDSPHGEDGPGDF-AHTGVPGHVPRSTCAPSPQREVLTVPEAN 1647
A ++I Q +A G G G A G G V T A P+ + + E +
Sbjct: 292 KASEKIL-----QVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES 346
Query: 1648 SEPWTLDTLGGERRPGVTAGILEMR-----NALGNQSTPAPPTGEVADTPLEPGKVAGAA 1702
S+ E +L+ + + +G S PA + P PGK A
Sbjct: 347 SD--------SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAV 398
Query: 1703 GEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTA 1762
+A+ +++ + S EA P + S KAP + +
Sbjct: 399 AKAQAGKREEDSQSSSEESDSEEEA---------------PAQAKP---SGKAPQVRAAS 440
Query: 1763 ALHGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRES 1822
A +SP + P P R +V V E + + EE +DRE+
Sbjct: 441 APAKESPRKGAA----PAPPRKTGPAAAQVQVGKQEEDSRS--------SSEESDSDREA 488
Query: 1823 PRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPA--------DL 1874
+ P +P+V K S G G + PV + PA P+ D
Sbjct: 489 -LAAMNAAQVKPLGKSPQV--KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDS 545
Query: 1875 ESPTLAAS-SYHGDVVGQV------STDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGD 1927
ES + +S S G+V V S I Q+ P ++ A PP A P
Sbjct: 546 ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQA-KPTSSPAKGPPQKA-------GPVAV 597
Query: 1928 RVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPP 1987
+V+A P D ++ SSDS ++ E P + T +A PA P + P+ +T
Sbjct: 598 QVKAEKPM--DNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTT---- 651
Query: 1988 EEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVD 2047
++ PV G ++ G+ P S + +P S + E
Sbjct: 652 ----ASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTG 707
Query: 2048 TFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS---------------TLSRSLSLQAS 2092
T+ S K + K SVP+ S T+++ + +
Sbjct: 708 LAVTVGQAKSVGKGLQVK-------AASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQE 760
Query: 2093 DFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKE 2152
D + + + E A +P T S + R PS K + T +
Sbjct: 761 DSESSEEESDSEEAAASPAQVKT-SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQA 819
Query: 2153 TQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEG 2212
Q+ P + + P N + T PS T + GP+ DS S+E
Sbjct: 820 KQRSPSK--VKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEE----DSGSSEE 873
Query: 2213 VVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSED 2272
+ P G KT + A + +P G S +
Sbjct: 874 ESDSEEEAETLAQVKPSG-KTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDS 932
Query: 2273 KSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAK 2332
SS + + + V K PL ++P TPA ++ + P ++
Sbjct: 933 GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ-AQAASTPRKARASE 991
Query: 2333 GTYTFDIDKWDDPNFNPFS---STSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSK-TP 2388
T + +D + P + + +P P K SS+ +
Sbjct: 992 STARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISD 1051
Query: 2389 SSPSKSPAS------FEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPL 2442
+ PA+ +PA++ ++ V G NK K K ++ T + S
Sbjct: 1052 GKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDS 1111
Query: 2443 SDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLS 2502
SD S P+ +V T + + E+ + D PS
Sbjct: 1112 SDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEE------TAAESSEDDVVAPSQSL 1165
Query: 2503 TFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDD-------APKKQALYLMFDTSQ 2555
T +P + + +++ + S+L DD P++ A L T
Sbjct: 1166 LSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGG 1225
Query: 2556 ESPVKSSPVRMSESPTPCSGSSFEETEALVN--TAAKNQHPVPRGLAPNQESHLQVPEKS 2613
+ + + S P +G+ T AL + T P P A Q S ++V +
Sbjct: 1226 KEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTEL 1285
Query: 2614 SQKE 2617
++E
Sbjct: 1286 LEQE 1289
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 79.3 bits (194), Expect = 5e-14
Identities = 202/840 (24%), Positives = 273/840 (32%), Gaps = 192/840 (22%)
Query: 82 KDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPP--EGCLASPAAAPEDGPQTQSPR 139
+ PQG +GP G P PP PP +G P E G Q ++
Sbjct: 930 RGPQGPQGPVGFPGPKGPPG---------------PPGKDGLPGHPGQRGETGFQGKT-- 972
Query: 140 REPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPG 199
P PG + P E + G P G++ ++G + + G
Sbjct: 973 ---GPPGPGGVVG-------PQGPTGETGPIGERGHPGPPGPPGEQ-GLPGAAGKEGAKG 1021
Query: 200 MSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQG 259
+P + G+ D P G GFP +G+ Q P +G
Sbjct: 1022 -------DPGPQGISGK-DGPAGLR--------GFP---GERGLPGAQGAP-----GLKG 1057
Query: 260 TESSAVLEKSPLKPMAPIPQDPAPRASDRERGQ-GEAPPQYLTDDLEFLRACHLPRSNSG 318
E P P P P S ERG G A P L P
Sbjct: 1058 GEG----------PQGP----PGPVGSPGERGSAGTAGPIGLPG---------RPGPQGP 1094
Query: 319 AAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQT 378
P E A ++ Q P G + P GLP PA AG G++ D ++ Q
Sbjct: 1095 PGPAGEKGAPGEKGPQGPAGR--DGVQGPVGLPGPA--GPAGSPGEDG-DKGEIGEPGQK 1149
Query: 379 GMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPG 438
G +G K G P PV P + E P F A PG
Sbjct: 1150 GSKGDKGEN----GPPGPPGLQGPVG-APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1204
Query: 439 SSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKG----EHPEGDPGEV-PAPS 493
+ G+P E D G +G G +G + P+G PG V
Sbjct: 1205 PPG--PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGG 1262
Query: 494 PQERGEHLNTEQSHEVQPGVPPPPLPK----EQSHEVQPGAPPPPLPKAPSESARGPPGP 549
E+GE E + PG PK E+ PGA PP A+GPPG
Sbjct: 1263 VGEKGE--PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP-------GAKGPPG- 1312
Query: 550 TDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPE 609
DG K G+ P PG P PP G+PG G+D D +
Sbjct: 1313 DDGPK-------------GNPGPVGFPGD----PGPP--GEPGP-AGQDGVGGDKGEDGD 1352
Query: 610 VGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHK---LGEE 666
G+ PS +A P PP GA G EA A G P K +G +
Sbjct: 1353 PGQPGPPGPSGEAGPPGPPGKRG--PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1410
Query: 667 DPVLPPVPDG-------AGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESE 719
P P P+G GE +P A +G P GL ++ + E
Sbjct: 1411 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG-------PPGPMGPPGLPGLKGDPGSKGE 1463
Query: 720 KSDFPPTPVAEVAPKAQEGE----STLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFH 775
K P + + P ++GE + G+G + P P GP
Sbjct: 1464 KGH--PGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP---------- 1511
Query: 776 AGVPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASE-WPLLSSEK---HLQ 831
G P P + + G T + G+P PG G + P+LSS+K H +
Sbjct: 1512 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTE 1571
Query: 832 PSQAQPETSIFDV-------------LKE-----------QAQPPENGKETSPSHPGFKD 867
QA + +I D LK+ Q P K+ SHP F D
Sbjct: 1572 GMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPD 1631
Score = 70.9 bits (172), Expect = 2e-11
Identities = 183/793 (23%), Positives = 247/793 (31%), Gaps = 126/793 (15%)
Query: 38 TPGSPDHRDASSIGSVGLGGFCTASESSASLDPC-LVSPEVTEPRKDPQGARGPEGSLLP 96
TPG+P G G+ G ++ P P + PQG GP+G + P
Sbjct: 671 TPGAP--------GQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGP 722
Query: 97 SPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPA 156
+ + + +P A+ PP P + G + P P P +P
Sbjct: 723 PGEKGPQGKPGLAGLPGADGPP----GHPGKEGQSGEK--GALGPPGPQGP----IGYPG 772
Query: 157 ERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPV----PLREPMKAP 212
R S G + + G K + + P P +A
Sbjct: 773 PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAG 832
Query: 213 LCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLK 272
G+ G + K G P RQG P P A + + P
Sbjct: 833 PTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRG 892
Query: 273 PMAPIPQDPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQES 332
P PR S RG P P+ SG + +
Sbjct: 893 QRGPT----GPRGSRGARGPTGKPG---------------PKGTSGG--DGPPGPPGERG 931
Query: 333 CQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVA 392
Q P G P G P P P G GK+ L GHP G RG Q
Sbjct: 932 PQGPQG--------PVGFPGPKGPP--GPPGKDGLP-----GHP--GQRGETGFQ----G 970
Query: 393 AGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPV 452
G P G V P+ PT E P P PG++ +E G P
Sbjct: 971 KTGPPGPGGVVGPQG----PTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAK--GDPG 1024
Query: 453 SADAAKEVVDAGLVGLERQVSDLGSKG-------EHPEGDPGEVPAPSPQERGEHLNTEQ 505
+ + AGL G + G++G E P+G PG P SP ERG
Sbjct: 1025 PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG--PVGSPGERGS------ 1076
Query: 506 SHEVQP-GVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAV 564
+ P G+P P P+ PP P + + +GP GP D V
Sbjct: 1077 AGTAGPIGLPGRPGPQ---------GPPGPAGEKGAPGEKGPQGPAG-----RDGVQGPV 1122
Query: 565 AKEGSRSPGDSP---GGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSD 621
G P SP G K E EP G G+ +GE+ VG + +
Sbjct: 1123 GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD-KGENGPPGPPGLQGPVGAPGI----AG 1177
Query: 622 AESRDHPSSHSAQPPRKG--GAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGE 679
+ P +KG GA GP G P + GE V P P G
Sbjct: 1178 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1237
Query: 680 PTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGE 739
P P+G G+ P ++ S G+G + PP PK + GE
Sbjct: 1238 PRGPQGP--NGADGPQGPPGSVGSVGGVGEKGE---PGEAGNPGPPGEAGVGGPKGERGE 1292
Query: 740 STLEIRKMGSCDGEGLLTSP--DQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTALI 797
E G+ G P D P+G G P PP A G+
Sbjct: 1293 KG-EAGPPGAAGPPGAKGPPGDDGPKGNPGPVG----FPGDPGPPGEPGPAGQDGVGG-- 1345
Query: 798 LDQDQQGIPSCPG 810
D+ + G P PG
Sbjct: 1346 -DKGEDGDPGQPG 1357
Score = 62.4 bits (150), Expect = 6e-09
Identities = 169/717 (23%), Positives = 230/717 (32%), Gaps = 104/717 (14%)
Query: 463 AGLVGLERQVSDLGSKGEH----PEGDPGEVPAPSPQ-------ERGEHLNTEQSHEVQP 511
AG+ G ++G +GE +G+PG P PQ E+G Q
Sbjct: 681 AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP-----QGKPGLA 735
Query: 512 GVP----PPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKE 567
G+P PP P ++ + GA PP P+ P G PGP G K D +
Sbjct: 736 GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPI----GYPGPR-GVK-GADGVRGLKGSK 789
Query: 568 GSRSPGDSPGGKEEAPEPPDGGDPGNL--QGEDSQAFSSKRDPEVGKDELSKPSSDAESR 625
G + PG K + D G+ G + +GED R G S + +
Sbjct: 790 GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 849
Query: 626 DHPSSHSAQPPRKGGAGHTD-----GPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEP 680
P P R+G G T G + + +G P G+ P P GA P
Sbjct: 850 GVPGL-PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 908
Query: 681 TVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGES 740
T G G P P + +G F + PP Q GE+
Sbjct: 909 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPG--PPGKDGLPGHPGQRGET 966
Query: 741 TLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTALILDQ 800
+ K G G G + P P G + H G P PP + L G D
Sbjct: 967 GFQ-GKTGP-PGPGGVVGPQGPTGETGPIGERG-HPGPPGPPGEQGLPGAAGKEGAKGDP 1023
Query: 801 DQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSP 860
QGI G +RG E+ L +Q P LK P G
Sbjct: 1024 GPQGISGKDGPAGLRG-------FPGERGLPGAQGAPG------LKGGEGP--QGPPGPV 1068
Query: 861 SHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTLS-DTPTSSPT 919
PG + + I +P P P G++ A G E Q P G P P
Sbjct: 1069 GSPGERGSAGTAGPIGLPGRPGPQGP-PGPAGEKGAPG-EKGPQGPAGRDGVQGPVGLPG 1126
Query: 920 DMVWESSLTEESELSAPTRQKLPALGEKRPEGACGD-GQSSRVSPPAAD-VLKDFSLAGN 977
S E+ + +GE +G+ GD G++ PP + +AG
Sbjct: 1127 PAGPAGSPGEDGDKG--------EIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1178
Query: 978 FSRKETCCTGQGPNKSQQALADALEEGSQHEEACQRHPGASEAADGCSPLWGLSKREMAS 1037
G+ + QQ + G + +E + PG G L GL
Sbjct: 1179 --------DGEPGPRGQQGMF-----GQKGDEGARGFPG----PPGPIGLQGLPGPPGEK 1221
Query: 1038 GNTGEAPPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQ 1097
G G+ P P P PG Q P + G V
Sbjct: 1222 GENGDVGPMGP----------------PGPPGPRGPQ-GPNGADGPQGPPGSVGSVGGVG 1264
Query: 1098 QKMECWATSDAESPKLLASFPSAGEQG--GEAGAAETGGSAGA-GDPGKQQAPEKPG 1151
+K E + P GE+G GEAG G GA G PG PG
Sbjct: 1265 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG 1321
Score = 47.4 bits (111), Expect = 2e-04
Identities = 176/795 (22%), Positives = 234/795 (29%), Gaps = 177/795 (22%)
Query: 1261 PRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTE 1320
PR + P G+P K +G P PG G + P Q G P +
Sbjct: 899 PRGSRGARGPTGKP--------GPKGTSGGDGPPGPPGERGPQGP--QGPVGFPGPKGPP 948
Query: 1321 GPVDSMPCLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETE-------GS 1373
GP P D +P + TG + PG G +G G+ E G
Sbjct: 949 GP----PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGP 1004
Query: 1374 MERMGEPSQDPKQGTSGGVD----TSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGE 1429
G P K+G G + + A L GFP E+ + GA PG
Sbjct: 1005 PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPG---------ERGLPGAQGAPGL 1055
Query: 1430 KAGAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPARLQVEKKQQLAGEAEISHLAL 1489
K G G P GP G PG + A P L
Sbjct: 1056 KGGEGPQG-------PPGPV----GSPGERGSAGTAGPIGL------------------- 1085
Query: 1490 QDPASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQL 1549
P GP G E+ PG ++ P+GP A G++G
Sbjct: 1086 --PGRPGPQGPPGPAGEKGAPG----------------EKGPQGP-AGRDGVQGPV---- 1122
Query: 1550 ERSRQELASGLPSPAATQELPVERAAAFQVA-PHSHGEEAVAQDRIPSGKQHQETSACDS 1608
GLP PA P E ++ P G + + P G
Sbjct: 1123 ---------GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG----------- 1162
Query: 1609 PHGEDGPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAGI 1668
P G GP G PG + P P+ + + E G PG I
Sbjct: 1163 PPGLQGP-----VGAPG-IAGGDGEPGPRGQQGMFGQKGDE-------GARGFPGPPGPI 1209
Query: 1669 LEMRNALGNQSTPAPP--TGEVADT-PLEPGKVAGAAGEAEGDITLSTAETQACASGDLP 1725
G Q P PP GE D P+ P G G Q D P
Sbjct: 1210 -------GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP------------QGPNGADGP 1250
Query: 1726 EAGTTRTFSVVA-GDLVLPGSCQDPACSDKAP--GMEGTAALHGDS----PARPQQAKEQ 1778
+ SV G+ PG +P +A G +G G++ A P AK
Sbjct: 1251 QGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGP 1310
Query: 1779 PGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGP------SMLPS 1832
PG + P G V P P P Q + D + +PGP + P
Sbjct: 1311 PGDDGP-KGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1369
Query: 1833 VPKKDAPR----VMDKVTSDETRGAEGTESSPVADDIIQPAAPADLESPTLAASSYHGDV 1888
P K P + +G G E P + P PA P G V
Sbjct: 1370 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPE-GLRGIPGPV 1428
Query: 1889 VGQVSTDLIAQSISPAAAHA-------GLPPSAAEH----IVSPSAPAGDRVEASTPSCP 1937
Q Q P G P S E ++ P G++ E P
Sbjct: 1429 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1488
Query: 1938 DPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV 1997
D P P+ P P P P+ + ST P ++ G
Sbjct: 1489 GTQGSPGAKGDGG----IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1544
Query: 1998 PVPDGPRSDSVEGSP 2012
P GP + ++ P
Sbjct: 1545 PGSPGPPGEVIQPLP 1559
Score = 38.9 bits (89), Expect = 0.076
Identities = 149/644 (23%), Positives = 198/644 (30%), Gaps = 108/644 (16%)
Query: 1345 EKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTG 1404
E P A +G+ AGE +G + G P +QG G TG
Sbjct: 821 EDGPEGPKGRAGPTGDPGPSGQAGE-KGKLGVPGLPGYPGRQGPKGS-----------TG 868
Query: 1405 FPDFREHIAKIFEKPVLGALATPGEKAGAGR--SAVGKDLTRPLGPEKLL--DGPPGVDV 1460
FP F + + V G G++ G S + T GP+ DGPPG
Sbjct: 869 FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPG--- 925
Query: 1461 TLLPAPPARLQVEKKQQLAGEAEISHLALQDPASDKLLGPAGLTWERNLPGAGVGKEMAG 1520
PP + Q G P GP G + LPG + G
Sbjct: 926 -----PPGERGPQGPQGPVG--------FPGPK-----GPPGPPGKDGLPGHPGQRGETG 967
Query: 1521 VPPTLREDERPEGPGAAW--PGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQ 1578
+ P GPG G G+ ER G P P Q LP
Sbjct: 968 ----FQGKTGPPGPGGVVGPQGPTGETGPIGERGHP----GPPGPPGEQGLP-------- 1011
Query: 1579 VAPHSHGEEAVAQDRIPSGKQHQETSACDSPHGEDG-PGDFAHTGVPGHVPRSTCAPSPQ 1637
+ G+E D P G S D P G G PG+ G G P PQ
Sbjct: 1012 ---GAAGKEGAKGDPGPQG-----ISGKDGPAGLRGFPGERGLPGAQG-APGLKGGEGPQ 1062
Query: 1638 REVLTV--PEANSEPWTLDTLGGERRPGVTA--GILEMRNALGNQSTPAPPTGEVADTPL 1693
V P T +G RPG G + A G + P + P+
Sbjct: 1063 GPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV 1122
Query: 1694 E---PGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPA 1750
P AG+ GE +GD Q + GD E G + G + PG A
Sbjct: 1123 GLPGPAGPAGSPGE-DGDKGEIGEPGQKGSKGDKGENGPPGPPGL-QGPVGAPGI----A 1176
Query: 1751 CSDKAPGMEGTAALHGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPP-EPDETHDPKLQ 1809
D PG G + G + A+ PGP PI G + PP E E D
Sbjct: 1177 GGDGEPGPRGQQGMFGQKG--DEGARGFPGPPGPI----GLQGLPGPPGEKGENGDV--- 1227
Query: 1810 HLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPA 1869
GP P P P+ + +D +G G+ S + +
Sbjct: 1228 ----------------GPMGPPGPPGPRGPQGPNG--ADGPQGPPGSVGS--VGGVGEKG 1267
Query: 1870 APADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRV 1929
P + +P + G G+ A A P + P G
Sbjct: 1268 EPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1327
Query: 1930 EASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPP 1973
+ P P PA D E + + P + A PP PP
Sbjct: 1328 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1371
Score = 33.1 bits (74), Expect = 4.2
Identities = 94/370 (25%), Positives = 124/370 (33%), Gaps = 98/370 (26%)
Query: 1215 AVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPCPVGEP 1274
AV +P +L+ GPP A P A G G++ + P PG+ P G P
Sbjct: 444 AVVEPG-MLVEGPPGPAGP---------AGIMGPP--GLQG-PTGPPGDPGDRG-PPGRP 489
Query: 1275 PLALENAASLKLFAGSLAPL-LQPGAAGGEIPAVQASSGSPKARTTE------GPVDSMP 1327
L A L G++ L + G G + P + A +A + GP M
Sbjct: 490 --GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMG 547
Query: 1328 CLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQG 1387
R P G ++G + + PG +G G G + G P D +G
Sbjct: 548 LTGR-PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPT-----GKPGKRGRPGADGGRG 601
Query: 1388 TSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGEKAGAGRSAVGKDLTRPLG 1447
G ++ GF G PG+K G P G
Sbjct: 602 MPGEPGAKGDR-----GFD---------------GLPGLPGDKGHRGERG-------PQG 634
Query: 1448 PEKLLDGPPGVDVTLLPAPPARLQVEKKQQLAGE-AEISHLALQDPASDKLLGPAGLTWE 1506
P GPPG D + GE EI L A GP GL
Sbjct: 635 PP----GPPGDD-----------------GMRGEDGEIGPRGLPGEA-----GPRGLLGP 668
Query: 1507 RNLPGAGVGKEMAGV--PPTLREDERPEG-PGAAWPGLEGQAYSQLERSRQELASGLPSP 1563
R PGA MAGV PP + + P+G PG PG +G Q GLP P
Sbjct: 669 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP--PGQQGNPGPQ----------GLPGP 716
Query: 1564 AATQELPVER 1573
P E+
Sbjct: 717 QGPIGPPGEK 726
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 79.3 bits (194), Expect = 5e-14
Identities = 202/840 (24%), Positives = 273/840 (32%), Gaps = 192/840 (22%)
Query: 82 KDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPP--EGCLASPAAAPEDGPQTQSPR 139
+ PQG +GP G P PP PP +G P E G Q ++
Sbjct: 879 RGPQGPQGPVGFPGPKGPPG---------------PPGKDGLPGHPGQRGETGFQGKT-- 921
Query: 140 REPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPG 199
P PG + P E + G P G++ ++G + + G
Sbjct: 922 ---GPPGPGGVVG-------PQGPTGETGPIGERGHPGPPGPPGEQ-GLPGAAGKEGAKG 970
Query: 200 MSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQG 259
+P + G+ D P G GFP +G+ Q P +G
Sbjct: 971 -------DPGPQGISGK-DGPAGLR--------GFP---GERGLPGAQGAP-----GLKG 1006
Query: 260 TESSAVLEKSPLKPMAPIPQDPAPRASDRERGQ-GEAPPQYLTDDLEFLRACHLPRSNSG 318
E P P P P S ERG G A P L P
Sbjct: 1007 GEG----------PQGP----PGPVGSPGERGSAGTAGPIGLPG---------RPGPQGP 1043
Query: 319 AAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQT 378
P E A ++ Q P G + P GLP PA AG G++ D ++ Q
Sbjct: 1044 PGPAGEKGAPGEKGPQGPAGR--DGVQGPVGLPGPA--GPAGSPGEDG-DKGEIGEPGQK 1098
Query: 379 GMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPG 438
G +G K G P PV P + E P F A PG
Sbjct: 1099 GSKGDKGEN----GPPGPPGLQGPVG-APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1153
Query: 439 SSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKG----EHPEGDPGEV-PAPS 493
+ G+P E D G +G G +G + P+G PG V
Sbjct: 1154 PPG--PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGG 1211
Query: 494 PQERGEHLNTEQSHEVQPGVPPPPLPK----EQSHEVQPGAPPPPLPKAPSESARGPPGP 549
E+GE E + PG PK E+ PGA PP A+GPPG
Sbjct: 1212 VGEKGE--PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP-------GAKGPPG- 1261
Query: 550 TDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPE 609
DG K G+ P PG P PP G+PG G+D D +
Sbjct: 1262 DDGPK-------------GNPGPVGFPGD----PGPP--GEPGP-AGQDGVGGDKGEDGD 1301
Query: 610 VGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHK---LGEE 666
G+ PS +A P PP GA G EA A G P K +G +
Sbjct: 1302 PGQPGPPGPSGEAGPPGPPGKRG--PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1359
Query: 667 DPVLPPVPDG-------AGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESE 719
P P P+G GE +P A +G P GL ++ + E
Sbjct: 1360 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG-------PPGPMGPPGLPGLKGDPGSKGE 1412
Query: 720 KSDFPPTPVAEVAPKAQEGE----STLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFH 775
K P + + P ++GE + G+G + P P GP
Sbjct: 1413 KGH--PGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP---------- 1460
Query: 776 AGVPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASE-WPLLSSEK---HLQ 831
G P P + + G T + G+P PG G + P+LSS+K H +
Sbjct: 1461 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTE 1520
Query: 832 PSQAQPETSIFDV-------------LKE-----------QAQPPENGKETSPSHPGFKD 867
QA + +I D LK+ Q P K+ SHP F D
Sbjct: 1521 GMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPD 1580
Score = 70.9 bits (172), Expect = 2e-11
Identities = 183/793 (23%), Positives = 247/793 (31%), Gaps = 126/793 (15%)
Query: 38 TPGSPDHRDASSIGSVGLGGFCTASESSASLDPC-LVSPEVTEPRKDPQGARGPEGSLLP 96
TPG+P G G+ G ++ P P + PQG GP+G + P
Sbjct: 620 TPGAP--------GQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGP 671
Query: 97 SPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPA 156
+ + + +P A+ PP P + G + P P P +P
Sbjct: 672 PGEKGPQGKPGLAGLPGADGPP----GHPGKEGQSGEK--GALGPPGPQGP----IGYPG 721
Query: 157 ERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPV----PLREPMKAP 212
R S G + + G K + + P P +A
Sbjct: 722 PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAG 781
Query: 213 LCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLK 272
G+ G + K G P RQG P P A + + P
Sbjct: 782 PTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRG 841
Query: 273 PMAPIPQDPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQES 332
P PR S RG P P+ SG + +
Sbjct: 842 QRGPT----GPRGSRGARGPTGKPG---------------PKGTSGG--DGPPGPPGERG 880
Query: 333 CQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVA 392
Q P G P G P P P G GK+ L GHP G RG Q
Sbjct: 881 PQGPQG--------PVGFPGPKGPP--GPPGKDGLP-----GHP--GQRGETGFQ----G 919
Query: 393 AGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPV 452
G P G V P+ PT E P P PG++ +E G P
Sbjct: 920 KTGPPGPGGVVGPQG----PTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAK--GDPG 973
Query: 453 SADAAKEVVDAGLVGLERQVSDLGSKG-------EHPEGDPGEVPAPSPQERGEHLNTEQ 505
+ + AGL G + G++G E P+G PG P SP ERG
Sbjct: 974 PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG--PVGSPGERGS------ 1025
Query: 506 SHEVQP-GVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAV 564
+ P G+P P P+ PP P + + +GP GP D V
Sbjct: 1026 AGTAGPIGLPGRPGPQ---------GPPGPAGEKGAPGEKGPQGPAG-----RDGVQGPV 1071
Query: 565 AKEGSRSPGDSP---GGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSD 621
G P SP G K E EP G G+ +GE+ VG + +
Sbjct: 1072 GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD-KGENGPPGPPGLQGPVGAPGI----AG 1126
Query: 622 AESRDHPSSHSAQPPRKG--GAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGE 679
+ P +KG GA GP G P + GE V P P G
Sbjct: 1127 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1186
Query: 680 PTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGE 739
P P+G G+ P ++ S G+G + PP PK + GE
Sbjct: 1187 PRGPQGP--NGADGPQGPPGSVGSVGGVGEKGE---PGEAGNPGPPGEAGVGGPKGERGE 1241
Query: 740 STLEIRKMGSCDGEGLLTSP--DQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTALI 797
E G+ G P D P+G G P PP A G+
Sbjct: 1242 KG-EAGPPGAAGPPGAKGPPGDDGPKGNPGPVG----FPGDPGPPGEPGPAGQDGVGG-- 1294
Query: 798 LDQDQQGIPSCPG 810
D+ + G P PG
Sbjct: 1295 -DKGEDGDPGQPG 1306
Score = 62.4 bits (150), Expect = 6e-09
Identities = 169/717 (23%), Positives = 230/717 (32%), Gaps = 104/717 (14%)
Query: 463 AGLVGLERQVSDLGSKGEH----PEGDPGEVPAPSPQ-------ERGEHLNTEQSHEVQP 511
AG+ G ++G +GE +G+PG P PQ E+G Q
Sbjct: 630 AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP-----QGKPGLA 684
Query: 512 GVP----PPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKE 567
G+P PP P ++ + GA PP P+ P G PGP G K D +
Sbjct: 685 GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPI----GYPGPR-GVK-GADGVRGLKGSK 738
Query: 568 GSRSPGDSPGGKEEAPEPPDGGDPGNL--QGEDSQAFSSKRDPEVGKDELSKPSSDAESR 625
G + PG K + D G+ G + +GED R G S + +
Sbjct: 739 GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 798
Query: 626 DHPSSHSAQPPRKGGAGHTD-----GPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEP 680
P P R+G G T G + + +G P G+ P P GA P
Sbjct: 799 GVPGL-PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 857
Query: 681 TVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGES 740
T G G P P + +G F + PP Q GE+
Sbjct: 858 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPG--PPGKDGLPGHPGQRGET 915
Query: 741 TLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTALILDQ 800
+ K G G G + P P G + H G P PP + L G D
Sbjct: 916 GFQ-GKTGP-PGPGGVVGPQGPTGETGPIGERG-HPGPPGPPGEQGLPGAAGKEGAKGDP 972
Query: 801 DQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSP 860
QGI G +RG E+ L +Q P LK P G
Sbjct: 973 GPQGISGKDGPAGLRG-------FPGERGLPGAQGAPG------LKGGEGP--QGPPGPV 1017
Query: 861 SHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTLS-DTPTSSPT 919
PG + + I +P P P G++ A G E Q P G P P
Sbjct: 1018 GSPGERGSAGTAGPIGLPGRPGPQGP-PGPAGEKGAPG-EKGPQGPAGRDGVQGPVGLPG 1075
Query: 920 DMVWESSLTEESELSAPTRQKLPALGEKRPEGACGD-GQSSRVSPPAAD-VLKDFSLAGN 977
S E+ + +GE +G+ GD G++ PP + +AG
Sbjct: 1076 PAGPAGSPGEDGDKG--------EIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1127
Query: 978 FSRKETCCTGQGPNKSQQALADALEEGSQHEEACQRHPGASEAADGCSPLWGLSKREMAS 1037
G+ + QQ + G + +E + PG G L GL
Sbjct: 1128 --------DGEPGPRGQQGMF-----GQKGDEGARGFPG----PPGPIGLQGLPGPPGEK 1170
Query: 1038 GNTGEAPPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQ 1097
G G+ P P P PG Q P + G V
Sbjct: 1171 GENGDVGPMGP----------------PGPPGPRGPQ-GPNGADGPQGPPGSVGSVGGVG 1213
Query: 1098 QKMECWATSDAESPKLLASFPSAGEQG--GEAGAAETGGSAGA-GDPGKQQAPEKPG 1151
+K E + P GE+G GEAG G GA G PG PG
Sbjct: 1214 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG 1270
Score = 47.4 bits (111), Expect = 2e-04
Identities = 176/795 (22%), Positives = 234/795 (29%), Gaps = 177/795 (22%)
Query: 1261 PRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTE 1320
PR + P G+P K +G P PG G + P Q G P +
Sbjct: 848 PRGSRGARGPTGKP--------GPKGTSGGDGPPGPPGERGPQGP--QGPVGFPGPKGPP 897
Query: 1321 GPVDSMPCLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETE-------GS 1373
GP P D +P + TG + PG G +G G+ E G
Sbjct: 898 GP----PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGP 953
Query: 1374 MERMGEPSQDPKQGTSGGVD----TSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGE 1429
G P K+G G + + A L GFP E+ + GA PG
Sbjct: 954 PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPG---------ERGLPGAQGAPGL 1004
Query: 1430 KAGAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPARLQVEKKQQLAGEAEISHLAL 1489
K G G P GP G PG + A P L
Sbjct: 1005 KGGEGPQG-------PPGPV----GSPGERGSAGTAGPIGL------------------- 1034
Query: 1490 QDPASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQL 1549
P GP G E+ PG ++ P+GP A G++G
Sbjct: 1035 --PGRPGPQGPPGPAGEKGAPG----------------EKGPQGP-AGRDGVQGPV---- 1071
Query: 1550 ERSRQELASGLPSPAATQELPVERAAAFQVA-PHSHGEEAVAQDRIPSGKQHQETSACDS 1608
GLP PA P E ++ P G + + P G
Sbjct: 1072 ---------GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG----------- 1111
Query: 1609 PHGEDGPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAGI 1668
P G GP G PG + P P+ + + E G PG I
Sbjct: 1112 PPGLQGP-----VGAPG-IAGGDGEPGPRGQQGMFGQKGDE-------GARGFPGPPGPI 1158
Query: 1669 LEMRNALGNQSTPAPP--TGEVADT-PLEPGKVAGAAGEAEGDITLSTAETQACASGDLP 1725
G Q P PP GE D P+ P G G Q D P
Sbjct: 1159 -------GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP------------QGPNGADGP 1199
Query: 1726 EAGTTRTFSVVA-GDLVLPGSCQDPACSDKAP--GMEGTAALHGDS----PARPQQAKEQ 1778
+ SV G+ PG +P +A G +G G++ A P AK
Sbjct: 1200 QGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGP 1259
Query: 1779 PGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGP------SMLPS 1832
PG + P G V P P P Q + D + +PGP + P
Sbjct: 1260 PGDDGP-KGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1318
Query: 1833 VPKKDAPR----VMDKVTSDETRGAEGTESSPVADDIIQPAAPADLESPTLAASSYHGDV 1888
P K P + +G G E P + P PA P G V
Sbjct: 1319 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPE-GLRGIPGPV 1377
Query: 1889 VGQVSTDLIAQSISPAAAHA-------GLPPSAAEH----IVSPSAPAGDRVEASTPSCP 1937
Q Q P G P S E ++ P G++ E P
Sbjct: 1378 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1437
Query: 1938 DPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV 1997
D P P+ P P P P+ + ST P ++ G
Sbjct: 1438 GTQGSPGAKGDGG----IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1493
Query: 1998 PVPDGPRSDSVEGSP 2012
P GP + ++ P
Sbjct: 1494 PGSPGPPGEVIQPLP 1508
Score = 38.9 bits (89), Expect = 0.076
Identities = 149/644 (23%), Positives = 198/644 (30%), Gaps = 108/644 (16%)
Query: 1345 EKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTG 1404
E P A +G+ AGE +G + G P +QG G TG
Sbjct: 770 EDGPEGPKGRAGPTGDPGPSGQAGE-KGKLGVPGLPGYPGRQGPKGS-----------TG 817
Query: 1405 FPDFREHIAKIFEKPVLGALATPGEKAGAGR--SAVGKDLTRPLGPEKLL--DGPPGVDV 1460
FP F + + V G G++ G S + T GP+ DGPPG
Sbjct: 818 FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPG--- 874
Query: 1461 TLLPAPPARLQVEKKQQLAGEAEISHLALQDPASDKLLGPAGLTWERNLPGAGVGKEMAG 1520
PP + Q G P GP G + LPG + G
Sbjct: 875 -----PPGERGPQGPQGPVG--------FPGPK-----GPPGPPGKDGLPGHPGQRGETG 916
Query: 1521 VPPTLREDERPEGPGAAW--PGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQ 1578
+ P GPG G G+ ER G P P Q LP
Sbjct: 917 ----FQGKTGPPGPGGVVGPQGPTGETGPIGERGHP----GPPGPPGEQGLP-------- 960
Query: 1579 VAPHSHGEEAVAQDRIPSGKQHQETSACDSPHGEDG-PGDFAHTGVPGHVPRSTCAPSPQ 1637
+ G+E D P G S D P G G PG+ G G P PQ
Sbjct: 961 ---GAAGKEGAKGDPGPQG-----ISGKDGPAGLRGFPGERGLPGAQG-APGLKGGEGPQ 1011
Query: 1638 REVLTV--PEANSEPWTLDTLGGERRPGVTA--GILEMRNALGNQSTPAPPTGEVADTPL 1693
V P T +G RPG G + A G + P + P+
Sbjct: 1012 GPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV 1071
Query: 1694 E---PGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPA 1750
P AG+ GE +GD Q + GD E G + G + PG A
Sbjct: 1072 GLPGPAGPAGSPGE-DGDKGEIGEPGQKGSKGDKGENGPPGPPGL-QGPVGAPGI----A 1125
Query: 1751 CSDKAPGMEGTAALHGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPP-EPDETHDPKLQ 1809
D PG G + G + A+ PGP PI G + PP E E D
Sbjct: 1126 GGDGEPGPRGQQGMFGQKG--DEGARGFPGPPGPI----GLQGLPGPPGEKGENGDV--- 1176
Query: 1810 HLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPA 1869
GP P P P+ + +D +G G+ S + +
Sbjct: 1177 ----------------GPMGPPGPPGPRGPQGPNG--ADGPQGPPGSVGS--VGGVGEKG 1216
Query: 1870 APADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRV 1929
P + +P + G G+ A A P + P G
Sbjct: 1217 EPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1276
Query: 1930 EASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPP 1973
+ P P PA D E + + P + A PP PP
Sbjct: 1277 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1320
Score = 33.1 bits (74), Expect = 4.2
Identities = 94/370 (25%), Positives = 124/370 (33%), Gaps = 98/370 (26%)
Query: 1215 AVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPCPVGEP 1274
AV +P +L+ GPP A P A G G++ + P PG+ P G P
Sbjct: 393 AVVEPG-MLVEGPPGPAGP---------AGIMGPP--GLQG-PTGPPGDPGDRG-PPGRP 438
Query: 1275 PLALENAASLKLFAGSLAPL-LQPGAAGGEIPAVQASSGSPKARTTE------GPVDSMP 1327
L A L G++ L + G G + P + A +A + GP M
Sbjct: 439 --GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMG 496
Query: 1328 CLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQG 1387
R P G ++G + + PG +G G G + G P D +G
Sbjct: 497 LTGR-PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPT-----GKPGKRGRPGADGGRG 550
Query: 1388 TSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGEKAGAGRSAVGKDLTRPLG 1447
G ++ GF G PG+K G P G
Sbjct: 551 MPGEPGAKGDR-----GFD---------------GLPGLPGDKGHRGERG-------PQG 583
Query: 1448 PEKLLDGPPGVDVTLLPAPPARLQVEKKQQLAGE-AEISHLALQDPASDKLLGPAGLTWE 1506
P GPPG D + GE EI L A GP GL
Sbjct: 584 PP----GPPGDD-----------------GMRGEDGEIGPRGLPGEA-----GPRGLLGP 617
Query: 1507 RNLPGAGVGKEMAGV--PPTLREDERPEG-PGAAWPGLEGQAYSQLERSRQELASGLPSP 1563
R PGA MAGV PP + + P+G PG PG +G Q GLP P
Sbjct: 618 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP--PGQQGNPGPQ----------GLPGP 665
Query: 1564 AATQELPVER 1573
P E+
Sbjct: 666 QGPIGPPGEK 675
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 79.3 bits (194), Expect = 5e-14
Identities = 202/840 (24%), Positives = 273/840 (32%), Gaps = 192/840 (22%)
Query: 82 KDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPP--EGCLASPAAAPEDGPQTQSPR 139
+ PQG +GP G P PP PP +G P E G Q ++
Sbjct: 918 RGPQGPQGPVGFPGPKGPPG---------------PPGKDGLPGHPGQRGETGFQGKT-- 960
Query: 140 REPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPG 199
P PG + P E + G P G++ ++G + + G
Sbjct: 961 ---GPPGPGGVVG-------PQGPTGETGPIGERGHPGPPGPPGEQ-GLPGAAGKEGAKG 1009
Query: 200 MSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQG 259
+P + G+ D P G GFP +G+ Q P +G
Sbjct: 1010 -------DPGPQGISGK-DGPAGLR--------GFP---GERGLPGAQGAP-----GLKG 1045
Query: 260 TESSAVLEKSPLKPMAPIPQDPAPRASDRERGQ-GEAPPQYLTDDLEFLRACHLPRSNSG 318
E P P P P S ERG G A P L P
Sbjct: 1046 GEG----------PQGP----PGPVGSPGERGSAGTAGPIGLPG---------RPGPQGP 1082
Query: 319 AAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQT 378
P E A ++ Q P G + P GLP PA AG G++ D ++ Q
Sbjct: 1083 PGPAGEKGAPGEKGPQGPAGR--DGVQGPVGLPGPA--GPAGSPGEDG-DKGEIGEPGQK 1137
Query: 379 GMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPG 438
G +G K G P PV P + E P F A PG
Sbjct: 1138 GSKGDKGEN----GPPGPPGLQGPVG-APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1192
Query: 439 SSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKG----EHPEGDPGEV-PAPS 493
+ G+P E D G +G G +G + P+G PG V
Sbjct: 1193 PPG--PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGG 1250
Query: 494 PQERGEHLNTEQSHEVQPGVPPPPLPK----EQSHEVQPGAPPPPLPKAPSESARGPPGP 549
E+GE E + PG PK E+ PGA PP A+GPPG
Sbjct: 1251 VGEKGE--PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP-------GAKGPPG- 1300
Query: 550 TDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPE 609
DG K G+ P PG P PP G+PG G+D D +
Sbjct: 1301 DDGPK-------------GNPGPVGFPGD----PGPP--GEPGP-AGQDGVGGDKGEDGD 1340
Query: 610 VGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHK---LGEE 666
G+ PS +A P PP GA G EA A G P K +G +
Sbjct: 1341 PGQPGPPGPSGEAGPPGPPGKRG--PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1398
Query: 667 DPVLPPVPDG-------AGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESE 719
P P P+G GE +P A +G P GL ++ + E
Sbjct: 1399 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG-------PPGPMGPPGLPGLKGDPGSKGE 1451
Query: 720 KSDFPPTPVAEVAPKAQEGE----STLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFH 775
K P + + P ++GE + G+G + P P GP
Sbjct: 1452 KGH--PGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP---------- 1499
Query: 776 AGVPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASE-WPLLSSEK---HLQ 831
G P P + + G T + G+P PG G + P+LSS+K H +
Sbjct: 1500 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTE 1559
Query: 832 PSQAQPETSIFDV-------------LKE-----------QAQPPENGKETSPSHPGFKD 867
QA + +I D LK+ Q P K+ SHP F D
Sbjct: 1560 GMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPD 1619
Score = 70.9 bits (172), Expect = 2e-11
Identities = 183/793 (23%), Positives = 247/793 (31%), Gaps = 126/793 (15%)
Query: 38 TPGSPDHRDASSIGSVGLGGFCTASESSASLDPC-LVSPEVTEPRKDPQGARGPEGSLLP 96
TPG+P G G+ G ++ P P + PQG GP+G + P
Sbjct: 659 TPGAP--------GQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGP 710
Query: 97 SPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPA 156
+ + + +P A+ PP P + G + P P P +P
Sbjct: 711 PGEKGPQGKPGLAGLPGADGPP----GHPGKEGQSGEK--GALGPPGPQGP----IGYPG 760
Query: 157 ERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPV----PLREPMKAP 212
R S G + + G K + + P P +A
Sbjct: 761 PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAG 820
Query: 213 LCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLK 272
G+ G + K G P RQG P P A + + P
Sbjct: 821 PTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRG 880
Query: 273 PMAPIPQDPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQES 332
P PR S RG P P+ SG + +
Sbjct: 881 QRGPT----GPRGSRGARGPTGKPG---------------PKGTSGG--DGPPGPPGERG 919
Query: 333 CQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVA 392
Q P G P G P P P G GK+ L GHP G RG Q
Sbjct: 920 PQGPQG--------PVGFPGPKGPP--GPPGKDGLP-----GHP--GQRGETGFQ----G 958
Query: 393 AGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPV 452
G P G V P+ PT E P P PG++ +E G P
Sbjct: 959 KTGPPGPGGVVGPQG----PTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAK--GDPG 1012
Query: 453 SADAAKEVVDAGLVGLERQVSDLGSKG-------EHPEGDPGEVPAPSPQERGEHLNTEQ 505
+ + AGL G + G++G E P+G PG P SP ERG
Sbjct: 1013 PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG--PVGSPGERGS------ 1064
Query: 506 SHEVQP-GVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAV 564
+ P G+P P P+ PP P + + +GP GP D V
Sbjct: 1065 AGTAGPIGLPGRPGPQ---------GPPGPAGEKGAPGEKGPQGPAG-----RDGVQGPV 1110
Query: 565 AKEGSRSPGDSP---GGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSD 621
G P SP G K E EP G G+ +GE+ VG + +
Sbjct: 1111 GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD-KGENGPPGPPGLQGPVGAPGI----AG 1165
Query: 622 AESRDHPSSHSAQPPRKG--GAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGE 679
+ P +KG GA GP G P + GE V P P G
Sbjct: 1166 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1225
Query: 680 PTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGE 739
P P+G G+ P ++ S G+G + PP PK + GE
Sbjct: 1226 PRGPQGP--NGADGPQGPPGSVGSVGGVGEKGE---PGEAGNPGPPGEAGVGGPKGERGE 1280
Query: 740 STLEIRKMGSCDGEGLLTSP--DQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTALI 797
E G+ G P D P+G G P PP A G+
Sbjct: 1281 KG-EAGPPGAAGPPGAKGPPGDDGPKGNPGPVG----FPGDPGPPGEPGPAGQDGVGG-- 1333
Query: 798 LDQDQQGIPSCPG 810
D+ + G P PG
Sbjct: 1334 -DKGEDGDPGQPG 1345
Score = 62.4 bits (150), Expect = 6e-09
Identities = 169/717 (23%), Positives = 230/717 (32%), Gaps = 104/717 (14%)
Query: 463 AGLVGLERQVSDLGSKGEH----PEGDPGEVPAPSPQ-------ERGEHLNTEQSHEVQP 511
AG+ G ++G +GE +G+PG P PQ E+G Q
Sbjct: 669 AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP-----QGKPGLA 723
Query: 512 GVP----PPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKE 567
G+P PP P ++ + GA PP P+ P G PGP G K D +
Sbjct: 724 GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPI----GYPGPR-GVK-GADGVRGLKGSK 777
Query: 568 GSRSPGDSPGGKEEAPEPPDGGDPGNL--QGEDSQAFSSKRDPEVGKDELSKPSSDAESR 625
G + PG K + D G+ G + +GED R G S + +
Sbjct: 778 GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 837
Query: 626 DHPSSHSAQPPRKGGAGHTD-----GPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEP 680
P P R+G G T G + + +G P G+ P P GA P
Sbjct: 838 GVPGL-PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 896
Query: 681 TVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGES 740
T G G P P + +G F + PP Q GE+
Sbjct: 897 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPG--PPGKDGLPGHPGQRGET 954
Query: 741 TLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTALILDQ 800
+ K G G G + P P G + H G P PP + L G D
Sbjct: 955 GFQ-GKTGP-PGPGGVVGPQGPTGETGPIGERG-HPGPPGPPGEQGLPGAAGKEGAKGDP 1011
Query: 801 DQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSP 860
QGI G +RG E+ L +Q P LK P G
Sbjct: 1012 GPQGISGKDGPAGLRG-------FPGERGLPGAQGAPG------LKGGEGP--QGPPGPV 1056
Query: 861 SHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTLS-DTPTSSPT 919
PG + + I +P P P G++ A G E Q P G P P
Sbjct: 1057 GSPGERGSAGTAGPIGLPGRPGPQGP-PGPAGEKGAPG-EKGPQGPAGRDGVQGPVGLPG 1114
Query: 920 DMVWESSLTEESELSAPTRQKLPALGEKRPEGACGD-GQSSRVSPPAAD-VLKDFSLAGN 977
S E+ + +GE +G+ GD G++ PP + +AG
Sbjct: 1115 PAGPAGSPGEDGDKG--------EIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1166
Query: 978 FSRKETCCTGQGPNKSQQALADALEEGSQHEEACQRHPGASEAADGCSPLWGLSKREMAS 1037
G+ + QQ + G + +E + PG G L GL
Sbjct: 1167 --------DGEPGPRGQQGMF-----GQKGDEGARGFPG----PPGPIGLQGLPGPPGEK 1209
Query: 1038 GNTGEAPPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQ 1097
G G+ P P P PG Q P + G V
Sbjct: 1210 GENGDVGPMGP----------------PGPPGPRGPQ-GPNGADGPQGPPGSVGSVGGVG 1252
Query: 1098 QKMECWATSDAESPKLLASFPSAGEQG--GEAGAAETGGSAGA-GDPGKQQAPEKPG 1151
+K E + P GE+G GEAG G GA G PG PG
Sbjct: 1253 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG 1309
Score = 47.4 bits (111), Expect = 2e-04
Identities = 176/795 (22%), Positives = 234/795 (29%), Gaps = 177/795 (22%)
Query: 1261 PRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTE 1320
PR + P G+P K +G P PG G + P Q G P +
Sbjct: 887 PRGSRGARGPTGKP--------GPKGTSGGDGPPGPPGERGPQGP--QGPVGFPGPKGPP 936
Query: 1321 GPVDSMPCLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETE-------GS 1373
GP P D +P + TG + PG G +G G+ E G
Sbjct: 937 GP----PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGP 992
Query: 1374 MERMGEPSQDPKQGTSGGVD----TSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGE 1429
G P K+G G + + A L GFP E+ + GA PG
Sbjct: 993 PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPG---------ERGLPGAQGAPGL 1043
Query: 1430 KAGAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPARLQVEKKQQLAGEAEISHLAL 1489
K G G P GP G PG + A P L
Sbjct: 1044 KGGEGPQG-------PPGPV----GSPGERGSAGTAGPIGL------------------- 1073
Query: 1490 QDPASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQL 1549
P GP G E+ PG ++ P+GP A G++G
Sbjct: 1074 --PGRPGPQGPPGPAGEKGAPG----------------EKGPQGP-AGRDGVQGPV---- 1110
Query: 1550 ERSRQELASGLPSPAATQELPVERAAAFQVA-PHSHGEEAVAQDRIPSGKQHQETSACDS 1608
GLP PA P E ++ P G + + P G
Sbjct: 1111 ---------GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG----------- 1150
Query: 1609 PHGEDGPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPGVTAGI 1668
P G GP G PG + P P+ + + E G PG I
Sbjct: 1151 PPGLQGP-----VGAPG-IAGGDGEPGPRGQQGMFGQKGDE-------GARGFPGPPGPI 1197
Query: 1669 LEMRNALGNQSTPAPP--TGEVADT-PLEPGKVAGAAGEAEGDITLSTAETQACASGDLP 1725
G Q P PP GE D P+ P G G Q D P
Sbjct: 1198 -------GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP------------QGPNGADGP 1238
Query: 1726 EAGTTRTFSVVA-GDLVLPGSCQDPACSDKAP--GMEGTAALHGDS----PARPQQAKEQ 1778
+ SV G+ PG +P +A G +G G++ A P AK
Sbjct: 1239 QGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGP 1298
Query: 1779 PGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGP------SMLPS 1832
PG + P G V P P P Q + D + +PGP + P
Sbjct: 1299 PGDDGP-KGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1357
Query: 1833 VPKKDAPR----VMDKVTSDETRGAEGTESSPVADDIIQPAAPADLESPTLAASSYHGDV 1888
P K P + +G G E P + P PA P G V
Sbjct: 1358 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPE-GLRGIPGPV 1416
Query: 1889 VGQVSTDLIAQSISPAAAHA-------GLPPSAAEH----IVSPSAPAGDRVEASTPSCP 1937
Q Q P G P S E ++ P G++ E P
Sbjct: 1417 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1476
Query: 1938 DPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV 1997
D P P+ P P P P+ + ST P ++ G
Sbjct: 1477 GTQGSPGAKGDGG----IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1532
Query: 1998 PVPDGPRSDSVEGSP 2012
P GP + ++ P
Sbjct: 1533 PGSPGPPGEVIQPLP 1547
Score = 38.9 bits (89), Expect = 0.076
Identities = 149/644 (23%), Positives = 198/644 (30%), Gaps = 108/644 (16%)
Query: 1345 EKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTG 1404
E P A +G+ AGE +G + G P +QG G TG
Sbjct: 809 EDGPEGPKGRAGPTGDPGPSGQAGE-KGKLGVPGLPGYPGRQGPKGS-----------TG 856
Query: 1405 FPDFREHIAKIFEKPVLGALATPGEKAGAGR--SAVGKDLTRPLGPEKLL--DGPPGVDV 1460
FP F + + V G G++ G S + T GP+ DGPPG
Sbjct: 857 FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPG--- 913
Query: 1461 TLLPAPPARLQVEKKQQLAGEAEISHLALQDPASDKLLGPAGLTWERNLPGAGVGKEMAG 1520
PP + Q G P GP G + LPG + G
Sbjct: 914 -----PPGERGPQGPQGPVG--------FPGPK-----GPPGPPGKDGLPGHPGQRGETG 955
Query: 1521 VPPTLREDERPEGPGAAW--PGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQ 1578
+ P GPG G G+ ER G P P Q LP
Sbjct: 956 ----FQGKTGPPGPGGVVGPQGPTGETGPIGERGHP----GPPGPPGEQGLP-------- 999
Query: 1579 VAPHSHGEEAVAQDRIPSGKQHQETSACDSPHGEDG-PGDFAHTGVPGHVPRSTCAPSPQ 1637
+ G+E D P G S D P G G PG+ G G P PQ
Sbjct: 1000 ---GAAGKEGAKGDPGPQG-----ISGKDGPAGLRGFPGERGLPGAQG-APGLKGGEGPQ 1050
Query: 1638 REVLTV--PEANSEPWTLDTLGGERRPGVTA--GILEMRNALGNQSTPAPPTGEVADTPL 1693
V P T +G RPG G + A G + P + P+
Sbjct: 1051 GPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV 1110
Query: 1694 E---PGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPA 1750
P AG+ GE +GD Q + GD E G + G + PG A
Sbjct: 1111 GLPGPAGPAGSPGE-DGDKGEIGEPGQKGSKGDKGENGPPGPPGL-QGPVGAPGI----A 1164
Query: 1751 CSDKAPGMEGTAALHGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPP-EPDETHDPKLQ 1809
D PG G + G + A+ PGP PI G + PP E E D
Sbjct: 1165 GGDGEPGPRGQQGMFGQKG--DEGARGFPGPPGPI----GLQGLPGPPGEKGENGDV--- 1215
Query: 1810 HLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPA 1869
GP P P P+ + +D +G G+ S + +
Sbjct: 1216 ----------------GPMGPPGPPGPRGPQGPNG--ADGPQGPPGSVGS--VGGVGEKG 1255
Query: 1870 APADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRV 1929
P + +P + G G+ A A P + P G
Sbjct: 1256 EPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1315
Query: 1930 EASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPP 1973
+ P P PA D E + + P + A PP PP
Sbjct: 1316 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1359
Score = 33.1 bits (74), Expect = 4.2
Identities = 94/370 (25%), Positives = 124/370 (33%), Gaps = 98/370 (26%)
Query: 1215 AVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPCPVGEP 1274
AV +P +L+ GPP A P A G G++ + P PG+ P G P
Sbjct: 432 AVVEPG-MLVEGPPGPAGP---------AGIMGPP--GLQG-PTGPPGDPGDRG-PPGRP 477
Query: 1275 PLALENAASLKLFAGSLAPL-LQPGAAGGEIPAVQASSGSPKARTTE------GPVDSMP 1327
L A L G++ L + G G + P + A +A + GP M
Sbjct: 478 --GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMG 535
Query: 1328 CLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQG 1387
R P G ++G + + PG +G G G + G P D +G
Sbjct: 536 LTGR-PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPT-----GKPGKRGRPGADGGRG 589
Query: 1388 TSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGEKAGAGRSAVGKDLTRPLG 1447
G ++ GF G PG+K G P G
Sbjct: 590 MPGEPGAKGDR-----GFD---------------GLPGLPGDKGHRGERG-------PQG 622
Query: 1448 PEKLLDGPPGVDVTLLPAPPARLQVEKKQQLAGE-AEISHLALQDPASDKLLGPAGLTWE 1506
P GPPG D + GE EI L A GP GL
Sbjct: 623 PP----GPPGDD-----------------GMRGEDGEIGPRGLPGEA-----GPRGLLGP 656
Query: 1507 RNLPGAGVGKEMAGV--PPTLREDERPEG-PGAAWPGLEGQAYSQLERSRQELASGLPSP 1563
R PGA MAGV PP + + P+G PG PG +G Q GLP P
Sbjct: 657 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP--PGQQGNPGPQ----------GLPGP 704
Query: 1564 AATQELPVER 1573
P E+
Sbjct: 705 QGPIGPPGEK 714
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 78.2 bits (191), Expect = 1e-13
Identities = 446/2123 (21%), Positives = 680/2123 (32%), Gaps = 354/2123 (16%)
Query: 40 GSPDHRDASSIGSVGLGGFCTASESSASLDPCLVSPEVTEPRKDPQGARGPEGSLLPSPP 99
G H S + G G S+ SAS PE +EP R PE + + P
Sbjct: 427 GLAQHVRCSGLWGHGTAGRERCSQDSASPASSTGLPEGSEPESSCC-PRTPEDGVDSASP 485
Query: 100 PSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERD 159
+Q + E P + PE G + +PR A D +A+ +
Sbjct: 486 SAQIGAERKAGGSLGEDPGLCIDGAGLGGPEQGGRL-TPRARSEEGASSDSSASTGSHEG 544
Query: 160 SSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLR-EPMKAPLCGEG- 217
SS P R ++E + G SP +S LR + ++A G+G
Sbjct: 545 SSEWGGRPQGCPGKARAETSQQEASEG------GDPASPALSLSSLRSDDLQAETQGQGT 598
Query: 218 DQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPI 277
+Q G + G + +G +S TP ++QQG + P +P
Sbjct: 599 EQATGAAVTREPLVLGLSCSWDSEGASS---TPSTCTSSQQGQRRHRSRASAMSSPSSPG 655
Query: 278 PQDPAPRASDRERGQGEAPPQYLTDDL--------EFLRACH---LPRSNSGAAPEAEVN 326
APR R + L + E RAC +PR SG++
Sbjct: 656 LGRVAPRGHPRHSHYRKDTHSPLDSSVTKQVPRPPERRRACQDGSVPRY-SGSSSSTRTQ 714
Query: 327 AASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPN 386
A+ + + P LP +L G S + P + + + P G G
Sbjct: 715 ASG--NLRPPSSGSLPSQDL-LGTSSATVTPAVHS---DFVSGVSPHNAPSAGWAGD--- 765
Query: 387 QVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVS 446
AG + P+ P H + S + AA + + S V
Sbjct: 766 ------AGSRTCSPAPIPP-----------HTSDSCSKSGAASLGEEARDTPQPSSPLVL 808
Query: 447 KAGMPVSADAAKEVVDAGLVGLER---------QVSDLGSKGEHPE-----GDPGEVPA- 491
+ G P + G VG R Q + +G PE G P
Sbjct: 809 QVGRP----------EQGAVGPHRSHCCSQPGTQPAQEAQRGPSPEASWLCGRYCPTPPR 858
Query: 492 --PSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGP 549
P PQ R + S P P+E + QPG P P GP
Sbjct: 859 GRPCPQRRSSSCGSTGSSHQSTARGPGGSPQEGTR--QPGPTPSP-------------GP 903
Query: 550 TDGA----KVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSK 605
GA + + S +++E + G P G+EEA G P +L +A +
Sbjct: 904 NSGASRRSSASQGAGSRGLSEEKTLRSGGGPQGQEEA----SGVSPSSLPRSSPEAVVRE 959
Query: 606 RDPEVGKDELSKPSSDAESRDHPSSHSAQPPR-KGGAGHTDGPHSQTAEADASGLPHKLG 664
+ ++ + A+ + + P G H+ + A+A L
Sbjct: 960 WLDNIPEEPILMTYELADETTGAAGGGLRGPEVDPGDDHSLEGLGEPAQAGQQSL----- 1014
Query: 665 EEDPVLPPVPDGA-----------GEPTVPEGAIWEGSGLQPKCPDTLQSREG-LGRMES 712
E DP P P+GA GE VP+GA EG P + RE G S
Sbjct: 1015 EGDPGQDPEPEGALLGSSDTGPQSGE-GVPQGAAPEGVSEAP--AEAGADREAPAGCRVS 1071
Query: 713 FLTLESEKSDFPPTPVAEVAPKAQEGESTLEI-RKMG---SCDGEGLLTSPDQPRGPACD 768
L S A + K S E+ R M SC L+T C
Sbjct: 1072 LRALPGRVSASTQIMRALMGSKQGRPSSVPEVSRPMARRLSCSAGALIT---------CL 1122
Query: 769 ASRQEFHAGVPHPPQGENLAADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEK 828
AS Q F E+L + Q + S + W E L S
Sbjct: 1123 ASLQLFE---------EDLGSPASKVRFKDSPRYQELLSISKDLWPGCDVGEDQLDSGLW 1173
Query: 829 HLQPSQAQPETSIFDVLKEQAQPPENGKETSPSHPG------------------------ 864
L SQA P+ + + +G + S G
Sbjct: 1174 ELTWSQALPDLGSHAMTENFTPTSSSGVDISSGSGGSGESSVPCAMDGTLVTQGTELPLK 1233
Query: 865 FKDQGADSSQIHVP--VEPQEDNNLPTHGGQEQALGSELQSQLPKGTLSDTPTSSPTDMV 922
+Q DS P +E Q+ PT + + + + + + SS + +
Sbjct: 1234 TSNQRPDSRTYESPGDLENQQQCCFPTFLNARACACATNEDEAERDS-EEQRASSNLEQL 1292
Query: 923 WESSLTEESELSAPTRQKLPALGEKRPEGACGDG-QSSRVSPPAADVLKDFSLAGNFSRK 981
E+++ EE +L E+ EG G+G Q V + G +
Sbjct: 1293 AENTVQEEVQL------------EETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEE 1340
Query: 982 ETCCTGQGPNKSQQALADALEEGSQ--HEEACQRHPGASEAADGCSPLWGLSKREMASGN 1039
G+G + + L + E G + EE Q E +G P GL + G
Sbjct: 1341 TKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQ----LEEVKEG--PEGGLQGEALEEGL 1394
Query: 1040 TGEAPPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQQK 1099
E P + SV + + A + G +D P E +E P P +
Sbjct: 1395 KEEGLP-EEGSVHGQEL-----SEASSPDGKGSQEDDPVQE--EEAGRASASAEPCPAEG 1446
Query: 1100 MECWATSDAESPKLLA-SFPSAGE-QGG---EAGAAETGGSAGAGDPGKQQAPEKPG--- 1151
E E P L+ + PSA E Q G E G + G+ G Q P +
Sbjct: 1447 TE----EPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAAER 1502
Query: 1152 ------EATLSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDALL---PARELGG 1202
A L C + L E+A + L + QD L A EL
Sbjct: 1503 SSSVACSAALDCDPIWVSVLLKKTEKAFLAHLASAVAELRARWGLQDNDLLDQMAAELQQ 1562
Query: 1203 IPRSTMDFSTH---QAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSA 1259
+ ST Q + ++ PP A L QR G++ +S+
Sbjct: 1563 DVAQRLQDSTKRELQKLQGRAGRMVLEPPREALTGELLLQTQ---QRRHRLRGLRNLSAF 1619
Query: 1260 DPRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQA------SSGS 1313
R G +G LE+ +L GS L A G E +A S S
Sbjct: 1620 SERTLG-----LGPLSFTLEDEPALSTALGS---QLGEEAEGEEFCPCEACVRKKVSPMS 1671
Query: 1314 PKAR--TTEGPVDSMPCLDRMPLLAKGKQATGEE------KAATAPGAGAKASG-EGMAG 1364
PKA T GP+ L ++ +G+ GE K T P + G EG G
Sbjct: 1672 PKATMGATRGPIKEAFDLQQILQRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLG 1731
Query: 1365 DAAGETEGSME-RMGEPSQ------DPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFE 1417
+ G E GE SQ DPK G + G + E+ + + H ++
Sbjct: 1732 PGLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQER--------EGKTHNSETSA 1783
Query: 1418 KPVLGALATPGEKAGAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPARLQVEKKQQ 1477
LG E+ G G S G+ + G E L G P + + +
Sbjct: 1784 GSELG----EAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPE 1839
Query: 1478 LAGEAEISHLALQDPASDKLLGPAGLTWERNLPGAGVGKEMAG-VPPTLREDERPEGPGA 1536
GEA+ ++ P ++ G +E G P + E PE G
Sbjct: 1840 AEGEAQPESEGVEAPEAE-----------------GDAQEAEGEAQPESEDVEAPEAEGE 1882
Query: 1537 AWPGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQV------APHSHGEEAVA 1590
A P E + E Q + G +P A +E E + + P S G EA
Sbjct: 1883 AQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQE 1942
Query: 1591 QDRI---PSGKQHQETSACDSPHGED----GPGDFAHTGVPGHVPRSTCAPSPQREVLTV 1643
+ G+ E+ +S E+ D V + P+ E +
Sbjct: 1943 AEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEA 2002
Query: 1644 PEANSEPWTLDTLGGERRPGVTA-------GILEMRNALGNQSTPAPPTGEVADTP---L 1693
PEA E + GV A E+ A P + + P
Sbjct: 2003 PEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEE 2062
Query: 1694 EPGKVAGAAGEAEGDITLSTAETQAC-ASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACS 1752
E + G EAEG+ + + A A G+ G+ + P
Sbjct: 2063 EAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETE 2122
Query: 1753 DKA-PGMEGTAALHGDSPARPQ----QAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPK 1807
+A P EG A + A+P+ +A++ G +P G E +E P+
Sbjct: 2123 GEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEG------IEAQEAEEEAQPE 2176
Query: 1808 LQHLAPEELHTDR-------ESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSP 1860
L+ + E + E+P P + +AP ++ + EG E +P
Sbjct: 2177 LEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPE----PEGVE-TP 2231
Query: 1861 VADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVS 1920
A+ QP + + + + +G ++ ++S SP P
Sbjct: 2232 EAEGEAQPESEGETQGEKKGSPQVS---LGDGQSEEASESSSPVPEDRPTP--------- 2279
Query: 1921 PSAPAGDRVEASTPSCPDPAKDLSRS------SDSEEAFETPESTTP-VKAPPAPPPPPP 1973
P +P GD S P+ + S DSE ++ +P K+ P
Sbjct: 2280 PPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHAERK 2339
Query: 1974 EVIPEPEVSTQPPPEEPGCGSET 1996
PE ST E P GS T
Sbjct: 2340 ATRMYPESSTSEQEEAP-LGSRT 2361
Score = 67.0 bits (162), Expect = 3e-10
Identities = 134/574 (23%), Positives = 197/574 (34%), Gaps = 73/574 (12%)
Query: 122 LASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKE 181
+ +P A E P+++ AP A GD A + P E P A E QP+
Sbjct: 1835 IEAPEAEGEAQPESEGVE---APEAEGDAQEA----EGEAQPESEDVEAPEAEGEAQPES 1887
Query: 182 EGQKSSFSFSSGIDQSPGM-SPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESR 240
E ++ + +S G +P +E E + G + E E A E+
Sbjct: 1888 EDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAA 1947
Query: 241 QGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMA-------------PIPQDPAPRASD 287
Q A Q PE+ Q E A E ++ + P +D ++
Sbjct: 1948 QE-AEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAE 2006
Query: 288 RERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPV--GAYLPHAE 345
E + E Q +D +E P+S A E E E QP G P AE
Sbjct: 2007 GEMQEAEEEAQPESDGVEAQ-----PKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAE 2061
Query: 346 LPWGLPSPALVPEAGGSG---KEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLP 402
+ V EA G E +D + +G Q G + + A G +
Sbjct: 2062 EE-AQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPE----AEGEAQKAEGI 2116
Query: 403 VSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKA---GMPVSADAAKE 459
+PE EA P S P A+ E G ++++ +A + A A+E
Sbjct: 2117 EAPETE-----GEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEE 2171
Query: 460 VVDAGLVGLERQVSDLGSKGE-HPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPL 518
L G+E ++ GE PE + E P E E QP +
Sbjct: 2172 EAQPELEGVEAPEAE----GEAQPESEGIEAP-------------EAEGEAQPELEGVEA 2214
Query: 519 PKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGG 578
P E E QP P+A E+ G T G K S + S SP
Sbjct: 2215 P-EAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVP 2273
Query: 579 KEEAPEPPD-GGD-----PGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHS 632
++ PP GGD PG+ G S SS + E D S D S+ +
Sbjct: 2274 EDRPTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGT 2333
Query: 633 AQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEE 666
RK + P S T+E + + L + E+
Sbjct: 2334 PHAERKATRMY---PESSTSEQEEAPLGSRTPEQ 2364
Score = 64.3 bits (155), Expect = 2e-09
Identities = 384/1817 (21%), Positives = 587/1817 (32%), Gaps = 318/1817 (17%)
Query: 64 SSASLDPCLVSPEVT--EPRKDPQ-GARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEG 120
SSA++ P + S V+ P P G G GS SP P H S S
Sbjct: 736 SSATVTPAVHSDFVSGVSPHNAPSAGWAGDAGSRTCSPAPIPP--HTSDS---------- 783
Query: 121 CLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPK 180
C S AA+ + R P P++P + P E+ + P++ + Q
Sbjct: 784 CSKSGAAS-----LGEEARDTPQPSSPLVLQVGRP-EQGAVGPHRSHCCSQPGTQPAQEA 837
Query: 181 EEGQKSSFSFSSG--IDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAE 238
+ G S+ G P P P R ++ CG G GG P
Sbjct: 838 QRGPSPEASWLCGRYCPTPPRGRPCPQR---RSSSCGS---TGSSHQSTARGPGGSPQEG 891
Query: 239 SRQGVASVQVTPEAPAA----AQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGE 294
+RQ + P + A+ A QG S + E+ L R+ +GQ E
Sbjct: 892 TRQPGPTPSPGPNSGASRRSSASQGAGSRGLSEEKTL------------RSGGGPQGQEE 939
Query: 295 APPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPA 354
A + LPRS+ PEA V ++P+ A+ G
Sbjct: 940 ASG---------VSPSSLPRSS----PEAVVREWLDNIPEEPILMTYELADETTG----- 981
Query: 355 LVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTE 414
A G G + H G+ +P Q + G P G PE +LL ++
Sbjct: 982 ----AAGGGLRGPEVDPGDDHSLEGLG--EPAQAGQQSLEGDP--GQDPEPEGALLGSSD 1033
Query: 415 EAHPASSLASFPAAQIPIAVEE-PGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVS 473
+ P P V E P + + + AG VS A G V Q+
Sbjct: 1034 TGPQSGE--GVPQGAAPEGVSEAPAEAGADREAPAGCRVSLRALP-----GRVSASTQIM 1086
Query: 474 D--LGSKGEHPEGDPGEVPAPSPQERG-------EHLNTEQSHEVQPGVPPPPL-----P 519
+GSK P P EV P + L + Q E G P + P
Sbjct: 1087 RALMGSKQGRPSSVP-EVSRPMARRLSCSAGALITCLASLQLFEEDLGSPASKVRFKDSP 1145
Query: 520 KEQ-----SHEVQPGAP--PPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSP 572
+ Q S ++ PG L E P G+ ++ +P + S
Sbjct: 1146 RYQELLSISKDLWPGCDVGEDQLDSGLWELTWSQALPDLGSHAMTENFTPTSSSGVDISS 1205
Query: 573 GDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHS 632
G G+ P DG QG + +S + P+ E + + P+ +
Sbjct: 1206 GSGGSGESSVPCAMDGTLV--TQGTELPLKTSNQRPDSRTYESPGDLENQQQCCFPTFLN 1263
Query: 633 AQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSG 692
A+ A + D + E AS +L E V + EG EG G
Sbjct: 1264 ARAC--ACATNEDEAERDSEEQRASSNLEQLAENT-----VQEEVQLEETKEGT--EGEG 1314
Query: 693 LQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDG 752
LQ + +++ G E + LE K E + Q+ E ++ ++ G
Sbjct: 1315 LQEEAVQLEETKTEEGLQEEGVQLEETK---------ETEGEGQQEEEA-QLEEIEETGG 1364
Query: 753 EGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTAL-----ILDQDQQGIPS 807
EGL Q G + ++ G+ QGE L L L + Q+ S
Sbjct: 1365 EGL-----QEEGVQLEEVKEGPEGGL----QGEALEEGLKEEGLPEEGSVHGQELSEASS 1415
Query: 808 CPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSPSHPGFKD 867
G +G+ + P+ E + A+P + + +E +PP + ET PS
Sbjct: 1416 PDG----KGSQEDDPVQEEEAGRASASAEPCPA--EGTEEPTEPPSHLSETDPS----AS 1465
Query: 868 QGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTLSDTPTSSPTDMVWESSL 927
+ SQ+ +E T GQE Q + + + D +W S L
Sbjct: 1466 ERQSGSQLEPGLEKPPG---ATMMGQEHTQAQPTQGAAERSSSVACSAALDCDPIWVSVL 1522
Query: 928 TEES--------------------------------ELSAPTRQKLPALGEKRPEGACGD 955
+++ EL Q+L ++ + G
Sbjct: 1523 LKKTEKAFLAHLASAVAELRARWGLQDNDLLDQMAAELQQDVAQRLQDSTKRELQKLQGR 1582
Query: 956 GQSSRVSPPAADVLKDFSLAG-----------NFSRKETCCTGQGPN----KSQQALADA 1000
+ PP + + L N S G GP + + AL+ A
Sbjct: 1583 AGRMVLEPPREALTGELLLQTQQRRHRLRGLRNLSAFSERTLGLGPLSFTLEDEPALSTA 1642
Query: 1001 L-----EEGSQHE----EACQRH---PGASEAADGCS--------PLWGLSKREMASGNT 1040
L EE E EAC R P + +A G + L + +R+
Sbjct: 1643 LGSQLGEEAEGEEFCPCEACVRKKVSPMSPKATMGATRGPIKEAFDLQQILQRKRGEHTD 1702
Query: 1041 GEAPPCQP-----DSVALLDAVPCLPALAPA---SPGVTPTQDAPETEACDETQE---GR 1089
GEA P D + L P PGV +D ++ + ++ G
Sbjct: 1703 GEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGVDEGEDGEGSQRLNRDKDPKLGE 1762
Query: 1090 QQPVPAPQQKMECWATSDAESPKLLASFPSAGE---QGGEAGAAETG------GSAGAG- 1139
+ Q++ S+ + L GE + GE G +G G A AG
Sbjct: 1763 AEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGG 1822
Query: 1140 --DPGKQ------QAPEKPGEATLSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQ 1191
DPG+ +APE GEA ++ +EA A ES E P A +
Sbjct: 1823 DQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEA--E 1880
Query: 1192 DALLPARELGGIPRSTMDFSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDS 1251
P E P + + + E PE + + L + + +E +
Sbjct: 1881 GEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEA--LETEGEDEPESEGA 1938
Query: 1252 GVKAVSSADPRAPGESP--CPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQA 1309
+ A A G++ V E A E A +L ++ A GE
Sbjct: 1939 EAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGE------ 1992
Query: 1310 SSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATGEEKAAT-APGAGAKASGEGM-AGDAA 1367
P++ E P A+G+ EE+A + G A+ EG A +
Sbjct: 1993 --AQPESEDVEAPE------------AEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVE 2038
Query: 1368 GET---EGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFE---KPVL 1421
GET EG + + + P+ Q A P+ + A+ E +P
Sbjct: 2039 GETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPES 2098
Query: 1422 GALATPGEKAGAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPARLQVEKK----QQ 1477
+ P E G + A G + PE + P + P Q E + Q
Sbjct: 2099 EGVEAP-EAEGEAQKAEGIE-----APETEGEAQPESEGIEAPEAEGEAQPESEGVEAQD 2152
Query: 1478 LAGEAEISHLALQDPASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLREDERPEGPGAA 1537
GEA+ ++ +++ P L G + P E PE G A
Sbjct: 2153 AEGEAQPESEGIEAQEAEEEAQP-------ELEGVEAPEAEGEAQPESEGIEAPEAEGEA 2205
Query: 1538 WPGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSG 1597
P LEG + E Q G+ +P A E E Q GE+ +
Sbjct: 2206 QPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQ------GEKKGSPQVSLGD 2259
Query: 1598 KQHQETSACDSPHGEDGPGDFAHTG--VPGHVPRSTCAPSPQREVLTVPEANSEPWTLDT 1655
Q +E S SP ED P G P P S PS R + W D+
Sbjct: 2260 GQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSR-----ASSWGNCWQKDS 2314
Query: 1656 -----LGGERRPGVTAGILEMRNALGNQSTPAPPTGEVADTPL---EPGKVAGAAGEAEG 1707
LG R P + + P T E + PL P + A + +
Sbjct: 2315 ENDHVLGDTRSPDAKSTGTPHAERKATRMYPESSTSEQEEAPLGSRTPEQGASEGYDLQE 2374
Query: 1708 DITL-STAETQACASGD 1723
D L S A T+A D
Sbjct: 2375 DQALGSLAPTEAVGRAD 2391
Score = 60.5 bits (145), Expect = 2e-08
Identities = 139/659 (21%), Positives = 218/659 (33%), Gaps = 118/659 (17%)
Query: 1744 GSCQDPACSDKAPGMEGTAALHGDSPARPQQAKEQPGPERPIPAGDGKVCV-SSPPEPDE 1802
G QDP SD G EG A + A+P E G E P GD + + PE ++
Sbjct: 1821 GGDQDPGQSD---GAEGIEAPEAEGEAQP----ESEGVEAPEAEGDAQEAEGEAQPESED 1873
Query: 1803 THDPKLQHLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVA 1862
P+ + A E D E+P + P E+ GAE +P A
Sbjct: 1874 VEAPEAEGEAQPE-SEDVETPEAEWEVQP-----------------ESEGAE----APEA 1911
Query: 1863 DDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPS 1922
+ QP E+ ++ A G+ A A AA+ +
Sbjct: 1912 EKEAQP------ETESVEALETEGE-----------DEPESEGAEAQEAEEAAQEAEGQT 1954
Query: 1923 APAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVS 1982
P + +E+ + ++ S+ EA E T + P E PE E
Sbjct: 1955 QPESEVIESQ-----EAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEA-PEAEGE 2008
Query: 1983 TQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDN 2042
Q EE P SD VE +P S A E + + G + D
Sbjct: 2009 MQEAEEEA-----------QPESDGVEA---QPKSEGEEAQEVEGETQKTEGDAQPESDG 2054
Query: 2043 IELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGN 2102
+E + + + + + EG+ + + D+ A
Sbjct: 2055 VEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDA-------------------QEAEGEAQ 2095
Query: 2103 PEAVAL-APDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEE- 2160
PE+ + AP+A + T+ P + + + E P E + D E
Sbjct: 2096 PESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEG 2155
Query: 2161 SLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGG 2220
P E + ++ E A+ P +E E P++ +++ AEG P G
Sbjct: 2156 EAQPESEGIEAQEAEEEAQ---PELEGVEAPEAEGEAQPESE-GIEAPEAEGEAQPELEG 2211
Query: 2221 GRVQNSPPVGRKTLPLTTAPEA-GEVTPSD----SGGQEDSPAKGLSVRLEFDYSEDKSS 2275
+ + PEA GE P G ++ SP L + SE S
Sbjct: 2212 VEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSP 2271
Query: 2276 WDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPND-------I 2328
+ PPP+ P P +RP + P + ND
Sbjct: 2272 VPEDRPTPPPS------PGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRS 2325
Query: 2329 PIAKGTYTFDIDKWDDPNFNPFSSTSKMQESP---KLPQQ----SYNFDPDTCDESVDP 2380
P AK T T ++ P SSTS+ +E+P + P+Q Y+ D S+ P
Sbjct: 2326 PDAKSTGTPHAER-KATRMYPESSTSEQEEAPLGSRTPEQGASEGYDLQEDQALGSLAP 2383
Score = 56.2 bits (134), Expect = 5e-07
Identities = 109/523 (20%), Positives = 180/523 (34%), Gaps = 82/523 (15%)
Query: 1802 ETHDPKLQHLAPEELHTDRESPR----------PGPSMLPSVPKKDAPRVMDKVTSDETR 1851
E D + +AP + HTD S R PG S P V + + ++ D+
Sbjct: 1699 EHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGVDEGEDGEGSQRLNRDKDP 1758
Query: 1852 GAEGTESSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLP 1911
E +A + E T + + G +G+ + + IS G
Sbjct: 1759 KLGEAEGDAMAQE---------REGKTHNSETSAGSELGEAEQE--GEGISERGETGGQG 1807
Query: 1912 PSAAEHIVSPSAPAGDRVEASTPSC-----PDPAKDLSRSSDSEEAFET----------- 1955
+++ +A GD+ + P+ + S+ EA E
Sbjct: 1808 SGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEA 1867
Query: 1956 -PESTTPVKAPPAPPPPPPEV--IPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEG-- 2010
PES V+AP A PE + PE + PE G + P ++SVE
Sbjct: 1868 QPESED-VEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALE 1926
Query: 2011 --SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNT 2068
P S A E+ + G + + IE + + +P + D + E +V T
Sbjct: 1927 TEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVET 1986
Query: 2069 RRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTK 2128
+ ++ P S+ + + A PE+ + S G A T+
Sbjct: 1987 QEAEGEAQPESEDVEAPEAE---GEMQEAEEEAQPESDGVEAQPKSEGEE-AQEVEGETQ 2042
Query: 2129 KPRPPSLKKKQTTKKPTETPPVKETQQE---------PDEESL---------VPSGENL- 2169
K + + + P +E + E P+ E + P E +
Sbjct: 2043 KTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVE 2102
Query: 2170 ASETKTESAKTEG-----------PSPALLEETPLEPAVGPKAACPLDSESAEGVVPPAS 2218
A E + E+ K EG P +E E P++ ++++ AEG P S
Sbjct: 2103 APEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESE-GVEAQDAEGEAQPES 2161
Query: 2219 GGGRVQNSPPVGRKTLPLTTAPEA-GEVTPSDSGGQEDSPAKG 2260
G Q + + L APEA GE P +S G E A+G
Sbjct: 2162 EGIEAQEAEEEAQPELEGVEAPEAEGEAQP-ESEGIEAPEAEG 2203
Score = 32.3 bits (72), Expect = 7.1
Identities = 100/515 (19%), Positives = 161/515 (31%), Gaps = 77/515 (14%)
Query: 2182 GPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAP- 2240
GP LE+ EPA+ L E+ P R + SP + T+ T P
Sbjct: 1627 GPLSFTLED---EPALSTALGSQLGEEAEGEEFCPCEACVRKKVSPMSPKATMGATRGPI 1683
Query: 2241 --------------------EAGEVTPSDSG----------GQEDSPAKGLSVRLEFDYS 2270
EA EV P + G E GLS D
Sbjct: 1684 KEAFDLQQILQRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGVDEG 1743
Query: 2271 EDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPI 2330
ED +Q+ N K+G+ M R E T A AE I
Sbjct: 1744 EDGEG--SQRLNRDKDPKLGEAEGDAMAQEREGKTHNSE----TSAGSELGEAEQEGEGI 1797
Query: 2331 AKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSS 2390
++ T + N ++ Q+ P QS + E+ + S+ +
Sbjct: 1798 SERGETGGQGSGHEDNLQGEAAAGGDQD----PGQSDGAEGIEAPEAEGEAQPESEGVEA 1853
Query: 2391 PSKSPASFEIPASAM-EANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQD 2449
P + E A E+ V+ A+ + ++T + P+ P ++
Sbjct: 1854 PEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEK 1913
Query: 2450 PTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETK 2509
A PET V + DE + + EA+ Q P+ + + E +
Sbjct: 1914 E---AQPETESVEALETEGEDEPESEGAEAQ-EAEEAAQEAEGQTQPESEVIESQEAEEE 1969
Query: 2510 FSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESP-----VKSSPV 2564
+E+++ E+E E G + P+ +D +A M + +E+ V++ P
Sbjct: 1970 AQPESEDVEALE-VEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPK 2028
Query: 2565 RMSESPTPCSGSS----------------------FEETEALVNTAAKNQHPVPRGLAPN 2602
E G + +E E V A HP +
Sbjct: 2029 SEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQ 2088
Query: 2603 QESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEG 2637
+ PE + EA G +E IE EG
Sbjct: 2089 EAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEG 2123
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 77.8 bits (190), Expect = 1e-13
Identities = 356/1568 (22%), Positives = 492/1568 (31%), Gaps = 279/1568 (17%)
Query: 484 GDPG-EVPAPSPQERGEHLNTEQSHEVQPGVPPPP-LPKEQSHEVQPGAPPP-------- 533
G PG + P P ++GE ++E PG+P P P EQ PGA P
Sbjct: 1430 GSPGPQGPVGPPGKKGEKGDSEDG---APGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPG 1486
Query: 534 PLPKAPSESARGPPGPT-----------DGAKVHEDSTSPAVAKEGSRSPGDSPG----- 577
PL +A + RGPPGP GAK E P ++G + PG
Sbjct: 1487 PLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGP-TGRQGEKGEPGRPGDPAVV 1545
Query: 578 GKEEAPEPPDGGDPGNLQGEDSQAFSSKR---------DPEVGKDELSKPSSDAESRDHP 628
G A + GD G + +R DP D + R P
Sbjct: 1546 GPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGP 1605
Query: 629 SSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPP-VPDGAGEPTVPEGAI 687
S P KG G GP G + G+E P P +P AGE + GA
Sbjct: 1606 PGDSGPPGEKGDPGR-PGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGL-RGAP 1663
Query: 688 WEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKM 747
+ K +G + ++ + P P G E +
Sbjct: 1664 GVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGE--PGPPGPPGRLVDTGPGAREKGEP 1721
Query: 748 GSCDGEGLLTSPDQPRGPACDASRQ-EFHAGVPHP--------PQGENLAADLGLTALIL 798
G EG P P R E G P P P GE D G L
Sbjct: 1722 GDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEK--GDRGPPGLDG 1779
Query: 799 DQDQQGIPSCPGEGWIRGAASE--------WPLLSSEKHLQPSQAQPETSIFDVLKEQAQ 850
G P G GAA + P L E+ L P + E +
Sbjct: 1780 RSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPP--GLPGKPGEDGK 1837
Query: 851 PPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPT-HGGQEQALGSELQSQLPKGT 909
P NGK P PG + G + +E + P G LG + LP G
Sbjct: 1838 PGLNGKNGEPGDPG--EDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLP-GP 1894
Query: 910 LSDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRPEGACGDGQSSRVSPPAAD-V 968
+ P + E + Q LP GE+ G G S P D +
Sbjct: 1895 VGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLP--GERGLRGEPG-------SVPNVDRL 1945
Query: 969 LKDFSLAGNFSRK--ETCCTGQG-----PNKSQQALADALEEGSQHEEACQRHPGASEAA 1021
L+ + + R+ ET G P + + D+ E+G +E PG
Sbjct: 1946 LETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLK 2005
Query: 1022 DGCSPLWGLSKREMASGNTGEAPPCQPDSVALLDAVPCLPALAPASPGV----TPTQDAP 1077
+A G G P P +A P +P L + GV P +
Sbjct: 2006 GDRGDPGPQGPPGLALGERG---PPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGE 2062
Query: 1078 ETEACDETQEGRQQP-----VPAPQQKMECWATSDAESPKLLASFPSAGEQG--GEAGA- 1129
E + ++GR P P P + D P L +GEQG G GA
Sbjct: 2063 RGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGL------SGEQGPPGLKGAK 2116
Query: 1130 AETGGSAGAGDPGKQQAPEKPGEATLSCGLLQTEHCLTSGEEASTSALRESCQAEHPMAS 1189
E G + G G + P G+ Q + GE
Sbjct: 2117 GEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMA--------GPEGKPG 2168
Query: 1190 CQDALLPARELGGIPRSTMDFSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAE 1249
Q P +GG H P L+GP A P P + G
Sbjct: 2169 LQGPRGPPGPVGG----------HGDPGPPGAPGLAGP---AGPQGPSGLKGEPGETGPP 2215
Query: 1250 DSGVK----AVSSADPRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGE-- 1303
G+ AV P P P G P L G + +PGA G +
Sbjct: 2216 GRGLTGPTGAVGLPGPPGPSGLVGPQGSPGL-----------PGQVGETGKPGAPGRDGA 2264
Query: 1304 --IPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATGEEKAATAPGA-GAKASGE 1360
+ S G P + GPV P + P A G+ G PGA G K +
Sbjct: 2265 SGKDGDRGSPGVPGSPGLPGPVG--PKGEPGPTGAPGQAVVG------LPGAKGEKGAPG 2316
Query: 1361 GMAGDAAGETEGSMER-----------------MGEPSQDPKQGTSGGVDTSSEQIATLT 1403
G+AGD GE +R G+P +D ++G G + +
Sbjct: 2317 GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVP 2376
Query: 1404 GFPDFREHIAKIFEKPVLGALATPGEKAGAGRSAVGKDLTRPLGP--EKLLDGPPGVD-- 1459
G P + + G PG G++ ++ +P GP E+ L GPPG +
Sbjct: 2377 GSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQP-GPSGERGLAGPPGREGI 2435
Query: 1460 --VTLLPAPPARLQVEKKQQLAGEAEISHLALQDPASDKLLGPAGLTWERNLPGAGVGKE 1517
P PP + L G+ + L P ++ G G+ E PG +
Sbjct: 2436 PGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGER--GEPGIRGEDGRPGQEGPRG 2493
Query: 1518 MAGVPPTLREDERPEGPGAAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAF 1577
+ G P + ER E GL+G ++ + G P P + ER
Sbjct: 2494 LTGPPGS--RGERGEKGDVGSAGLKG------DKGDSAVILGPPGPRGAKGDMGER---- 2541
Query: 1578 QVAPHSHGEEAVAQDRIPSGKQHQETSACDSPHGEDG-PGDFAHTGVPGHVPRSTCAPSP 1636
G + D+ P G + G G PGD G+PG R P
Sbjct: 2542 -------GPRGLDGDKGPRG-----DNGDPGDKGSKGEPGDKGSAGLPG--LRGLLGPQG 2587
Query: 1637 QREVLTVPEANSEPWTLDTLG-----------------GERRPGVTAGILEMRNALGNQS 1679
Q +P P G GER G+ + G
Sbjct: 2588 QPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAG 2647
Query: 1680 TPAPP-----TGEVADTPLEPGKVAGAAGE-----AEGDITLSTAETQACASGDLPEAGT 1729
P P GE+ + P PG+ +GA G+ +GD + Q GD E G
Sbjct: 2648 PPGRPGLAGHKGEMGE-PGVPGQ-SGAPGKEGLIGPKGD---RGFDGQPGPKGDQGEKGE 2702
Query: 1730 TRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAALHGDSPARPQQAKEQPGPERPIPAGD 1789
T + G P+ +D + G G G P P+ + Q G P
Sbjct: 2703 RGTPGI--------GGFPGPSGNDGSAGPPGPPGSVG--PRGPEGLQGQKGERGP----P 2748
Query: 1790 GKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSDE 1849
G+ V +P P AP E E RPGP+ P K +A +T D+
Sbjct: 2749 GERVVGAPGVPG----------APGE---RGEQGRPGPAG-PRGEKGEA-----ALTEDD 2789
Query: 1850 TRGAEGTESSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAG 1909
RG E S Q A P SY D G + +S A
Sbjct: 2790 IRGFVRQEMSQHCACQGQFIASGSRPLP-----SYAADTAGSQLHAVPVLRVSHAEEEER 2844
Query: 1910 LPPSAAEH 1917
+PP E+
Sbjct: 2845 VPPEDDEY 2852
Score = 67.0 bits (162), Expect = 3e-10
Identities = 227/1001 (22%), Positives = 314/1001 (31%), Gaps = 183/1001 (18%)
Query: 69 DPCLVSPEVTEPRKDP--------------QGARGPEGSLLPSPPPSQEREHPSSSMPFA 114
DP +V P V P+ + QG RGP G +LP P + P P
Sbjct: 1541 DPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGP--KGDPGDRGPIG 1598
Query: 115 ECPPEGCLASPAAAPED-GPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSA 173
L A P D GP P + P PG P RD V
Sbjct: 1599 -------LTGRAGPPGDSGP----PGEKGDPGRPGPPGPVGPRGRDGE--------VGEK 1639
Query: 174 GRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQ--PG--------GF 223
G E P + G G+ +PG+ + P+ +GDQ PG G
Sbjct: 1640 GDEGPPGDPGLPGKAG-ERGLRGAPGV---------RGPVGEKGDQGDPGEDGRNGSPGS 1689
Query: 224 ESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPI------ 277
+ + PP + V + E +G E + P P AP
Sbjct: 1690 SGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEG 1749
Query: 278 ------PQ-DPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQ 330
PQ DP R E+G P L+ P +GAA +A
Sbjct: 1750 FRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAG------ 1803
Query: 331 ESCQQPVGAYLPHAELPWGLPSPALVP----EAGGSGKEALDTIDVQ-GHP-QTGMRGTK 384
P LP GLP P+ P + G GK L+ + + G P + G +G K
Sbjct: 1804 ----DPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEK 1859
Query: 385 PNQVVCVAAGGQ-PEG--GLP--VSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGS 439
+ G P+G G P + P+ P P P P
Sbjct: 1860 GDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGT------GPKG 1913
Query: 440 SSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEH--------PEGDPGEVPA 491
E+ SK + + + ++R + G K E +P
Sbjct: 1914 DRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPV 1973
Query: 492 PSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTD 551
P + + + EQ + G P P E+ + G P P P + RGPPGP+
Sbjct: 1974 PERRRGPKGDSGEQGPPGKEG--PIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSG 2031
Query: 552 GAKVHEDSTSPAV-------------------AKEGSRSP--GDSPGGKEEAPEPPDGGD 590
A P + ++G R D P G P PP
Sbjct: 2032 LAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPG 2091
Query: 591 PGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGH-----TD 645
P E S ++ P K +P S+ + P P KG G D
Sbjct: 2092 PKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGD--QGPKGDRGVPGIKGDRGEPGPRGQD 2149
Query: 646 GPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPKCPDTLQSRE 705
G E +G K G + P PP P G P GA P+ P L+
Sbjct: 2150 GNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEP 2209
Query: 706 G-LGRMESFLTLESEKSDF--PPTPVAEVAPKAQEG--ESTLEIRKMGSCDGEGLLTSPD 760
G G LT + PP P V P+ G E K G+ +G
Sbjct: 2210 GETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDG 2269
Query: 761 QPRGPACDASRQEFHAGVPHP--PQGENLAADLGLTALILDQDQQGIPSCPGE----GWI 814
P S G+P P P+GE A++ G+P GE G +
Sbjct: 2270 DRGSPGVPGS-----PGLPGPVGPKGEPGPTGAPGQAVV------GLPGAKGEKGAPGGL 2318
Query: 815 RGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSPSHPGFK-DQGADSS 873
G P ++ L + E E P E+G++ +P GFK D G
Sbjct: 2319 AGDLVGEPGAKGDRGLPGPRG--EKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVP 2376
Query: 874 QIHVPVEP---QEDNNLPTHGGQEQALGSELQSQLPKGTLSDTPTSSPTDMVWESSLTEE 930
P P + D LP G +G Q+ P+G + S E
Sbjct: 2377 GSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTG-PRGEMGQPGPSG-----------ER 2424
Query: 931 SELSAPTRQKLPA-LGEKRPEGACGDGQSSRVSPPAADVLK 970
P R+ +P LG P G+ G PP A LK
Sbjct: 2425 GLAGPPGREGIPGPLGPPGPPGSVG--------PPGASGLK 2457
Score = 58.5 bits (140), Expect = 9e-08
Identities = 247/1044 (23%), Positives = 319/1044 (30%), Gaps = 231/1044 (22%)
Query: 1038 GNTGEAPPCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQ 1097
G+ GE P P + P LP L P SPG Q PV P
Sbjct: 1403 GDRGERGPPGPGEGGIAPGEPGLPGL-PGSPGP-------------------QGPVGPPG 1442
Query: 1098 QKMECWATSDAESPKLLASFPSAGEQG--GEAGAAETGGSAG-------AGDPGKQQAPE 1148
+K E + D +P L S GEQG G GA G G AG+ G++ P
Sbjct: 1443 KKGEKGDSEDG-APGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPG 1501
Query: 1149 KPGEATLSCGLLQTEHCLTSGEEASTSALRESCQAEHP--MASCQDALL-PARELGGI-P 1204
G L + G T E + P A A+ P E G + P
Sbjct: 1502 PAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGP 1561
Query: 1205 RSTMDFSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAP 1264
+ Q P L+L G P + + G DP P
Sbjct: 1562 AGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRP 1621
Query: 1265 GESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGEIPAVQASSGSPKARTTEGPVD 1324
G P PVG P + K G P PG +P G A GPV
Sbjct: 1622 GP-PGPVG--PRGRDGEVGEK---GDEGPPGDPG-----LPGKAGERGLRGAPGVRGPVG 1670
Query: 1325 SMPCLDRMPLLAKGKQAT-GEEKAATAPGAGAKASGEGMAGDAAG-----ETEGSMERMG 1378
KG Q GE+ +PG+ G G +T G
Sbjct: 1671 E-----------KGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKG 1719
Query: 1379 EPSQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGEKAGAGRSAV 1438
EP ++G G L G P E+ + G PG + G
Sbjct: 1720 EPGDRGQEGPRGPKGDPG-----LPGAPG---------ERGIEGFRGPPGPQGDPG---- 1761
Query: 1439 GKDLTRPLGPEKLLDGPPGVDVTLLPAPPARLQVEKKQQLAGEAEISHLALQ--DPASDK 1496
+ P G EK GPPG+D R ++ K AG + + A + DP D
Sbjct: 1762 ---VRGPAG-EKGDRGPPGLD--------GRSGLDGKPGAAGPSGPNGAAGKAGDPGRD- 1808
Query: 1497 LLGPAGLTWERNLPGAGVGKEMAGVP-----PTLR-EDERPEGPG----------AAWPG 1540
G GL E+ LPG + G P P L ++ P PG + G
Sbjct: 1809 --GLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASG 1866
Query: 1541 LEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSGKQH 1600
EG+ + ER A G+ P LP V P G V P G +
Sbjct: 1867 REGRDGPKGERG----APGILGPQGPPGLPGP------VGPPGQGFPGVPGGTGPKGDRG 1916
Query: 1601 QETSACDSPHGEDG-PGDFAHTGVPGHVPR-------STCAPSPQREV-----------L 1641
+ S GE G PG+ G PG VP + S RE+ L
Sbjct: 1917 ETGSK-----GEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFL 1971
Query: 1642 TVPEANSEPWTLDTLGGERRPGVTA--GILEMRNALGNQSTPAP--PTGEVADTPLEPGK 1697
VPE P G + PG G R G++ P P P G PG
Sbjct: 1972 PVPERRRGP--KGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGP 2029
Query: 1698 VAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPG 1757
+G AGE G + +A G+ G G+ G + D PG
Sbjct: 2030 -SGLAGEP-GKPGIPGLPGRAGGVGEAGRPGER-------GERGEKGERGEQG-RDGPPG 2079
Query: 1758 MEGTAALHGDSPARPQQAKEQPGPERPIPAGD-GKVCVSSPPEPDETHDPKLQHLAPEEL 1816
+ GT G P P+ + ++PGP G G P + PK P +
Sbjct: 2080 LPGTPGPPG--PPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPG-I 2136
Query: 1817 HTDRESPRP-GPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADLE 1875
DR P P G P +P + RG G E P + P P
Sbjct: 2137 KGDRGEPGPRGQDGNPGLPGE--------------RGMAGPEGKP---GLQGPRGPP--- 2176
Query: 1876 SPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEASTPS 1935
P H P A + P+ P G P
Sbjct: 2177 --------------------------GPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPG 2210
Query: 1936 -CPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGS 1994
P + L T P A P PP P + P+ S P + G
Sbjct: 2211 ETGPPGRGL---------------TGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGK 2255
Query: 1995 ETVPVPDGPR-SDSVEGSPFRPPS 2017
P DG D GSP P S
Sbjct: 2256 PGAPGRDGASGKDGDRGSPGVPGS 2279
Score = 52.8 bits (125), Expect = 5e-06
Identities = 157/664 (23%), Positives = 216/664 (32%), Gaps = 88/664 (13%)
Query: 1260 DPRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQPGAAGGE----IPAVQASSGSPK 1315
DP PG + P + P A + F G+ PG AG P ++ S G P
Sbjct: 1273 DPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPG 1332
Query: 1316 ARTTEGPVDSMPCLDRMPLLAKGKQ-ATGEEKAATAPGAGAKASGEGMAGDAAGETEGSM 1374
R G +R P KG+ A G+ PG + G +G G
Sbjct: 1333 PRGDPG--------ERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSG-----PPGPR 1379
Query: 1375 ERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGEKAGAG 1434
+G+P G G + G P E E + G +PG + G
Sbjct: 1380 GPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVG 1439
Query: 1435 RSAVGKDLTRPLGPEKLLDGPPGVDVTLLP-APPARLQVEKKQQLAGEAEISHLALQDPA 1493
+ L G PG P PP + + + G L +
Sbjct: 1440 PPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPG-------PLGEAG 1492
Query: 1494 SDKLLGPAGLTWERNLPGAGVGKEMAGVP-----PTLREDERPEGPGAAWPGLEGQAYSQ 1548
GP G R LPG G+ A P PT R+ E+ E P + G A +
Sbjct: 1493 EKGERGPPGPAGSRGLPGV-AGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAG 1551
Query: 1549 LERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSGKQHQETSACDS 1608
+ + ++ G P + ER V P G + DR P G +
Sbjct: 1552 PKGEKGDV--GPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIG-----LTGRAG 1604
Query: 1609 PHGEDGP----GDFAHTGVPGHV-PRSTCAPSPQREVLTVPEANSEPWTLDTLGGERRPG 1663
P G+ GP GD G PG V PR ++ P P G PG
Sbjct: 1605 PPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPG 1664
Query: 1664 VTAGILEM----------RNALGNQSTPAPPTGEVADTPLEPGKV--AGAAGEAEGDITL 1711
V + E RN S P GE P PG++ G +G+
Sbjct: 1665 VRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGE-PGPPGPPGRLVDTGPGAREKGEPGD 1723
Query: 1712 STAETQACASGD--LPEAGTTRTFSVVAGDLVLPGSCQDPACSDKA--------PGMEGT 1761
E GD LP A R G PG DP A PG++G
Sbjct: 1724 RGQEGPRGPKGDPGLPGAPGERGIEGFRGP---PGPQGDPGVRGPAGEKGDRGPPGLDGR 1780
Query: 1762 AALHGD----SPARPQQAKEQPG-PERP-IPAGDGKVCVSSPPEPDETHDPKLQHLAPEE 1815
+ L G P+ P A + G P R +P G+ + P P P L P +
Sbjct: 1781 SGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGP-----PGL----PGK 1831
Query: 1816 LHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSDET--RGAEGTESSPVADDIIQPAAPAD 1873
D + G + P P +D R +K S + G +G + A I+ P P
Sbjct: 1832 PGEDGKPGLNGKNGEPGDPGEDG-RKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPG 1890
Query: 1874 LESP 1877
L P
Sbjct: 1891 LPGP 1894
Score = 52.8 bits (125), Expect = 5e-06
Identities = 182/791 (23%), Positives = 243/791 (30%), Gaps = 152/791 (19%)
Query: 60 TASESSASLDPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPE 119
T ESS S P PE K G +GP G P P + P + PP
Sbjct: 1962 TWDESSGSFLPV---PERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPP- 2017
Query: 120 GCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQP 179
G P P + P PG V AGR +
Sbjct: 2018 GLALGERGPPGPSGLAGEPGKPGIPGLPG-----------------RAGGVGEAGRPGER 2060
Query: 180 KEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAP----------LCGEGDQPGGFESQEKE 229
E G+K G D PG+ P P L GE PG ++ +
Sbjct: 2061 GERGEKGERG-EQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEP 2119
Query: 230 AAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPL----KPMAPIPQDP-APR 284
+ G + +GV ++ P Q E+ KP P+ P P
Sbjct: 2120 GSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPV 2179
Query: 285 ASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAY-LPH 343
+ G AP L P+ SG E P GA LP
Sbjct: 2180 GGHGDPGPPGAPG---------LAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPG 2230
Query: 344 AELPWGLP----SPALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEG 399
P GL SP L + G +GK D + G RG+ G P
Sbjct: 2231 PPGPSGLVGPQGSPGLPGQVGETGKPGAPGRD-GASGKDGDRGSP-------GVPGSPGL 2282
Query: 400 GLPVSPEPSLLTPTEEAHPASSLASFPAAQ---------IPIAVEEPGSSSRESV-SKAG 449
PV P+ P P ++ P A+ V EPG+ + G
Sbjct: 2283 PGPVGPKGE---PGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRG 2339
Query: 450 MPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEV 509
A A E D G G + G KG+ G PG P P L
Sbjct: 2340 EKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGL------ 2393
Query: 510 QPGVPPPP----LPKEQSHEVQPGAPPP---------------PLPKAPSESARGPPG-- 548
PG+P P P + + G P P P P P GPPG
Sbjct: 2394 -PGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPP----GPPGSV 2448
Query: 549 -PTDGAKVHEDSTSPAVAKEGSRSPGDSPG--GKEEAP--EPPDG--GDPGN-------- 593
P + + D P V G R PG G++ P E P G G PG+
Sbjct: 2449 GPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKG 2508
Query: 594 ------LQGE--DSQAFSSKRDPEVGKDELSKPSSDAESRDH-PSSHSAQPPRKGGAGHT 644
L+G+ DS P K ++ + D P + P KG G
Sbjct: 2509 DVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKG-- 2566
Query: 645 DGPHSQTAEADASGLPHKLGEEDPV-------LPPVPDGAGEPTVPEGAIWEGSGLQPKC 697
+ + ++GLP G P +P P G+ VP G E +
Sbjct: 2567 -----EPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVP-GIRGEKGDVGFMG 2620
Query: 698 PDTLQSREGLGRMESFLTLESEKSD----FPPTPVAEVAPKAQEGESTLEIRKMGSCDGE 753
P L+ G ++ L+ EK D PP K + GE + + G+ E
Sbjct: 2621 PRGLKGERG---VKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVP-GQSGAPGKE 2676
Query: 754 GLLTSPDQPRG 764
GL+ P RG
Sbjct: 2677 GLI-GPKGDRG 2686
Score = 50.1 bits (118), Expect = 3e-05
Identities = 304/1385 (21%), Positives = 418/1385 (30%), Gaps = 266/1385 (19%)
Query: 504 EQSHEVQPGVPPPPLPKEQSHEVQPG-------APPPPLPKAPSES-ARGPPGPTDGAKV 555
+ S QP P P+ + + +PG PP P P + A GP GP A
Sbjct: 1235 QASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSAT- 1293
Query: 556 HEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDEL 615
A + G PG A P G PG L+G L
Sbjct: 1294 -------AKGERGFPGADGRPGSPGRAGNPGTPGAPG-LKGSPG---------------L 1330
Query: 616 SKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPD 675
P D R P +P G +GP GLP + G+ P PP P
Sbjct: 1331 PGPRGDPGERG-PRGPKGEPGAPGQVIGGEGP----------GLPGRKGDPGPSGPPGPR 1379
Query: 676 G-------AGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPV 728
G G P +P A+ G + + G+ E L S P PV
Sbjct: 1380 GPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLP-GLPGSPGPQGPV 1438
Query: 729 AEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLA 788
K ++G+S +G P QP P G PP
Sbjct: 1439 GPPGKKGEKGDSE-----------DGAPGLPGQPGSPG--------EQGPRGPPGAIGPK 1479
Query: 789 ADLGLTALILDQDQQGIPSCPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQ 848
D G + + ++G PG RG P ++ + + P + K +
Sbjct: 1480 GDRGFPGPLGEAGEKGERGPPGPAGSRGL----PGVAGRPGAKGPEGPPGPTGRQGEKGE 1535
Query: 849 AQPPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKG 908
P + P+ G K + D V P G+ G L G
Sbjct: 1536 PGRPGDPAVVGPAVAGPKGEKGD-------VGPAGPRGATGVQGERGPPGLVLPGD--PG 1586
Query: 909 TLSDTPTSSPTDMVWESSLTEES----ELSAPTRQKLPALGEKRPEGACGD-GQSSRVSP 963
D P + + +S E P R P G P G G+ G+ P
Sbjct: 1587 PKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPP--GPVGPRGRDGEVGEKGDEGP 1644
Query: 964 PAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQHEEACQRHPGASEAADG 1023
P D L G + +G + + + ++G E+ PG+S
Sbjct: 1645 PG-----DPGLPGKAGERGL----RGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSG---- 1691
Query: 1024 CSPLWGLSKREMASGNTGEAPPCQPDSVALLDAVPCLPAL---------APASPGVTPTQ 1074
G+ GE P P L+D P P P P
Sbjct: 1692 ------------PKGDRGEPGPPGPPG-RLVDTGPGAREKGEPGDRGQEGPRGPKGDPGL 1738
Query: 1075 DAPETEACDETQEGRQQPVPAPQQKMECWATSDAESPKLLASFPSAGEQGGEAGAAETGG 1134
E E G P P + D P L G+ G + G
Sbjct: 1739 PGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGA 1798
Query: 1135 SAGAGDPGKQQAPEKPGEATLSCGLLQTEHCLTSGEEASTSALRESCQAEHPMASCQDAL 1194
+ AGDPG+ P GE L GE+ ++ + P +
Sbjct: 1799 AGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKG- 1857
Query: 1195 LPARELGGIPRSTMDFSTHQAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVK 1254
+ G R D + P L GPP + P P G G +
Sbjct: 1858 -EKGDSGASGREGRDGPKGER-GAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDR 1915
Query: 1255 AV--SSADPRAPGESPCPVGEPPLALENAASLKLFAGSLAPLLQ------PGAAGGEIPA 1306
S + PGE GEP ++ N L AG A L+ ++G +P
Sbjct: 1916 GETGSKGEQGLPGERGLR-GEPG-SVPNVDRLLETAGIKASALREIVETWDESSGSFLPV 1973
Query: 1307 VQ------ASSGSPKARTTEGPVD-----------SMPCLDRMPLLAKGKQA-------T 1342
+ SG EGP+ P P LA G++
Sbjct: 1974 PERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLA 2033
Query: 1343 GEEKAATAPGAGAKASGEGMAGDAAGETE-GSMERMGEPSQDPKQGTSG----------- 1390
GE PG +A G G AG E G GE +D G G
Sbjct: 2034 GEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPK 2093
Query: 1391 -GVDTSSEQIATLTGFPDFREHIAKIFEKPVLGALATPGEKAGAGRSAVGKDLTRPLGPE 1449
VD ++ G P + K G+ G K G + D P GP
Sbjct: 2094 VSVDEPGPGLSGEQGPPGLKG------AKGEPGSNGDQGPKGDRGVPGIKGDRGEP-GP- 2145
Query: 1450 KLLDGPPGVDVTLLPAPPARLQVEKKQQLAGEAEISHLALQDPASDKLLGPAGLTWERNL 1509
+ DG PG LP E K L G + P GP G +
Sbjct: 2146 RGQDGNPG-----LPGERGMAGPEGKPGLQGP--------RGPP-----GPVGGHGDPGP 2187
Query: 1510 PGAGVGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQLERSRQELASGLPSPAATQEL 1569
PGA P L P+GP GL+G+ R GL P L
Sbjct: 2188 PGA----------PGLAGPAGPQGPS----GLKGEPGETGPPGR-----GLTGPTGAVGL 2228
Query: 1570 PVERAAAFQVAPHSHGEEAVAQDRIPSGKQHQETSACDSPHGEDG----PGDFAHTGVPG 1625
P + V P G + +GK D G+DG PG G+PG
Sbjct: 2229 PGPPGPSGLVGP--QGSPGLPGQVGETGK--PGAPGRDGASGKDGDRGSPGVPGSPGLPG 2284
Query: 1626 HV-PRSTCAP--SPQREVLTVPEANSEPWTLDTLGGERRPGVTAG-ILEMRNALGNQSTP 1681
V P+ P +P + V+ +P A E + PG AG ++ A G++ P
Sbjct: 2285 PVGPKGEPGPTGAPGQAVVGLPGAKGE---------KGAPGGLAGDLVGEPGAKGDRGLP 2335
Query: 1682 APPTGEVADTPLEPGKVAGAAGEA--EGDITLSTAETQACASGD----LPEAGTTRTFSV 1735
P GE + AG AGE G+ A GD +P +
Sbjct: 2336 G-PRGEKGE--------AGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPG 2386
Query: 1736 VAGDLVLPGSCQDPACSDKAPGMEGTAALHGDSPARPQQAKEQPGPERPIPAGDGKVCVS 1795
V GDL LPG PG G G + R + + P ER + G+ +
Sbjct: 2387 VKGDLGLPG----------LPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIP 2436
Query: 1796 SPPEP 1800
P P
Sbjct: 2437 GPLGP 2441
Score = 45.8 bits (107), Expect = 6e-04
Identities = 170/710 (23%), Positives = 221/710 (31%), Gaps = 151/710 (21%)
Query: 81 RKDPQGARGPEGSLLPSPP-PSQEREHPSSSMPFAECPP--EGCLASPAAAPEDGPQ--- 134
R P G G G P PP P + P + + PP +G P + + GP+
Sbjct: 2074 RDGPPGLPGTPGP--PGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDR 2131
Query: 135 ----TQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKS---- 186
+ R EP P D P ER AG E +P +G +
Sbjct: 2132 GVPGIKGDRGEPGPRGQ-DGNPGLPGERGM------------AGPEGKPGLQGPRGPPGP 2178
Query: 187 -SFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPG--GFESQEKEAAGGFPPAESRQGV 243
G +PG++ P + L GE + G G A G P G+
Sbjct: 2179 VGGHGDPGPPGAPGLAG-PAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGL 2237
Query: 244 ASVQVTPEAPAAAQQ-------GTESSAVLEKSPLKPMAP-IPQDPAPRASDRERGQGEA 295
Q +P P + G + ++ + P P P P P E G A
Sbjct: 2238 VGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGA 2297
Query: 296 PPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSP-A 354
P Q + LP GA E A VG P A+ GLP P
Sbjct: 2298 PGQAVVG---------LP----GAKGE---KGAPGGLAGDLVGE--PGAKGDRGLPGPRG 2339
Query: 355 LVPEAGGSGKEALDTIDVQ-GHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPT 413
EAG +G+ D Q G P G +G K + V V P G P + L P
Sbjct: 2340 EKGEAGRAGEPGDPGEDGQKGAP--GPKGFKGDPGVGVPGSPGPPG--PPGVKGDLGLPG 2395
Query: 414 EEAHPASSLASFPAAQIPIA-VEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQV 472
P + FP P + +PG S + AG P + G G
Sbjct: 2396 LPGAPG--VVGFPGQTGPRGEMGQPGPSGERGL--AGPPGREGIPGPLGPPGPPGSVGPP 2451
Query: 473 SDLGSKGEHPEGDPGEVPAPSPQ-ERGEH-LNTEQSHEVQPG----VPPPPLPKEQSHEV 526
G KG+ +GDPG V P P+ ERGE + E Q G PP E+ +
Sbjct: 2452 GASGLKGD--KGDPG-VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKG 2508
Query: 527 QPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAV--AKEGSRSPGDSPGGKEEAPE 584
G+ K S GPPGP GAK P +G R PG K E
Sbjct: 2509 DVGSAGLKGDKGDSAVILGPPGPR-GAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGE 2567
Query: 585 PPDGG------------------------DPGN-----------------------LQGE 597
P D G DPG+ L+GE
Sbjct: 2568 PGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGE 2627
Query: 598 DSQAFSSKRDPEVG----------------KDELSKPSSDAESRDHPSSHSAQPPRKGGA 641
+ D E G K E+ +P +S P G
Sbjct: 2628 RGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGF 2687
Query: 642 GHTDGPHSQTAEADA------SGLPHKLGEEDPVLPPVPDGAGEPTVPEG 685
GP E G P G + PP P G+ P PEG
Sbjct: 2688 DGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEG 2737
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.126 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 150,170,986
Number of Sequences: 37866
Number of extensions: 9745946
Number of successful extensions: 78125
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 409
Number of HSP's successfully gapped in prelim test: 2770
Number of HSP's that attempted gapping in prelim test: 35573
Number of HSP's gapped (non-prelim): 30249
length of query: 2948
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2828
effective length of database: 13,703,598
effective search space: 38753775144
effective search space used: 38753775144
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.