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Search of human proteins with 149944516
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149944516 tet oncogene family member 3 [Homo sapiens]
(1660 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149944516 tet oncogene family member 3 [Homo sapiens] 3421 0.0
gi|187761317 tet oncogene family member 2 isoform a [Homo sapiens] 606 e-173
gi|156139122 CXXC finger 6 [Homo sapiens] 507 e-143
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 96 3e-19
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 91 7e-18
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 88 6e-17
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 87 1e-16
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 86 3e-16
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 86 3e-16
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 86 3e-16
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 86 3e-16
gi|163965366 nascent polypeptide-associated complex alpha subuni... 85 7e-16
gi|47132519 Ras association and pleckstrin homology domains 1 is... 79 5e-14
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 77 2e-13
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 77 2e-13
gi|116284392 mucin 2 precursor [Homo sapiens] 76 3e-13
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 75 5e-13
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 75 7e-13
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 75 7e-13
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 74 2e-12
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 73 2e-12
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 71 8e-12
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 71 8e-12
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 71 8e-12
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 70 2e-11
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 69 3e-11
gi|116063558 tet oncogene family member 2 isoform b [Homo sapiens] 68 8e-11
gi|150170670 piccolo isoform 2 [Homo sapiens] 68 8e-11
gi|150378539 piccolo isoform 1 [Homo sapiens] 68 8e-11
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 67 1e-10
>gi|149944516 tet oncogene family member 3 [Homo sapiens]
Length = 1660
Score = 3421 bits (8870), Expect = 0.0
Identities = 1660/1660 (100%), Positives = 1660/1660 (100%)
Query: 1 MDSGPVYHGDSRQLSASGVPVNGAREPAGPSLLGTGGPWRVDQKPDWEAAPGPAHTARLE 60
MDSGPVYHGDSRQLSASGVPVNGAREPAGPSLLGTGGPWRVDQKPDWEAAPGPAHTARLE
Sbjct: 1 MDSGPVYHGDSRQLSASGVPVNGAREPAGPSLLGTGGPWRVDQKPDWEAAPGPAHTARLE 60
Query: 61 DAHDLVAFSAVAEAVSSYGALSTRLYETFNREMSREAGNNSRGPRPGPEGCSAGSEDLDT 120
DAHDLVAFSAVAEAVSSYGALSTRLYETFNREMSREAGNNSRGPRPGPEGCSAGSEDLDT
Sbjct: 61 DAHDLVAFSAVAEAVSSYGALSTRLYETFNREMSREAGNNSRGPRPGPEGCSAGSEDLDT 120
Query: 121 LQTALALARHGMKPPNCNCDGPECPDYLEWLEGKIKSVVMEGGEERPRLPGPLPPGEAGL 180
LQTALALARHGMKPPNCNCDGPECPDYLEWLEGKIKSVVMEGGEERPRLPGPLPPGEAGL
Sbjct: 121 LQTALALARHGMKPPNCNCDGPECPDYLEWLEGKIKSVVMEGGEERPRLPGPLPPGEAGL 180
Query: 181 PAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSH 240
PAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSH
Sbjct: 181 PAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSH 240
Query: 241 STPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPRTEFPE 300
STPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPRTEFPE
Sbjct: 241 STPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPRTEFPE 300
Query: 301 AWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAP 360
AWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAP
Sbjct: 301 AWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAP 360
Query: 361 SSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPS 420
SSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPS
Sbjct: 361 SSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPS 420
Query: 421 APGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPR 480
APGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPR
Sbjct: 421 APGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPR 480
Query: 481 EAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDS 540
EAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDS
Sbjct: 481 EAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDS 540
Query: 541 LLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDP 600
LLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDP
Sbjct: 541 LLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDP 600
Query: 601 ENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPTL 660
ENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPTL
Sbjct: 601 ENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPTL 660
Query: 661 SGFLESPLKYLDTPTKSLLDTPAKRAQAEFPTCDCVEQIVEKDEGPYYTHLGSGPTVASI 720
SGFLESPLKYLDTPTKSLLDTPAKRAQAEFPTCDCVEQIVEKDEGPYYTHLGSGPTVASI
Sbjct: 661 SGFLESPLKYLDTPTKSLLDTPAKRAQAEFPTCDCVEQIVEKDEGPYYTHLGSGPTVASI 720
Query: 721 RELMEERYGEKGKAIRIEKVIYTGKEGKSSRGCPIAKWVIRRHTLEEKLLCLVRHRAGHH 780
RELMEERYGEKGKAIRIEKVIYTGKEGKSSRGCPIAKWVIRRHTLEEKLLCLVRHRAGHH
Sbjct: 721 RELMEERYGEKGKAIRIEKVIYTGKEGKSSRGCPIAKWVIRRHTLEEKLLCLVRHRAGHH 780
Query: 781 CQNAVIVILILAWEGIPRSLGDTLYQELTDTLRKYGNPTSRRCGLNDDRTCACQGKDPNT 840
CQNAVIVILILAWEGIPRSLGDTLYQELTDTLRKYGNPTSRRCGLNDDRTCACQGKDPNT
Sbjct: 781 CQNAVIVILILAWEGIPRSLGDTLYQELTDTLRKYGNPTSRRCGLNDDRTCACQGKDPNT 840
Query: 841 CGASFSFGCSWSMYFNGCKYARSKTPRKFRLAGDNPKEEEVLRKSFQDLATEVAPLYKRL 900
CGASFSFGCSWSMYFNGCKYARSKTPRKFRLAGDNPKEEEVLRKSFQDLATEVAPLYKRL
Sbjct: 841 CGASFSFGCSWSMYFNGCKYARSKTPRKFRLAGDNPKEEEVLRKSFQDLATEVAPLYKRL 900
Query: 901 APQAYQNQVTNEEIAIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTK 960
APQAYQNQVTNEEIAIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTK
Sbjct: 901 APQAYQNQVTNEEIAIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTK 960
Query: 961 EDNRCVGKIPEDEQLHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEP 1020
EDNRCVGKIPEDEQLHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEP
Sbjct: 961 EDNRCVGKIPEDEQLHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEP 1020
Query: 1021 AKSCRQRQLEARKAAAEKKKIQKEKLSTPEKIKQEALELAGITSDPGLSLKGGLSQQGLK 1080
AKSCRQRQLEARKAAAEKKKIQKEKLSTPEKIKQEALELAGITSDPGLSLKGGLSQQGLK
Sbjct: 1021 AKSCRQRQLEARKAAAEKKKIQKEKLSTPEKIKQEALELAGITSDPGLSLKGGLSQQGLK 1080
Query: 1081 PSLKVEPQNHFSSFKYSGNAVVESYSVLGNCRPSDPYSMNSVYSYHSYYAQPSLTSVNGF 1140
PSLKVEPQNHFSSFKYSGNAVVESYSVLGNCRPSDPYSMNSVYSYHSYYAQPSLTSVNGF
Sbjct: 1081 PSLKVEPQNHFSSFKYSGNAVVESYSVLGNCRPSDPYSMNSVYSYHSYYAQPSLTSVNGF 1140
Query: 1141 HSKYALPSFSYYGFPSSNPVFPSQFLGPGAWGHSGSSGSFEKKPDLHALHNSLSPAYGGA 1200
HSKYALPSFSYYGFPSSNPVFPSQFLGPGAWGHSGSSGSFEKKPDLHALHNSLSPAYGGA
Sbjct: 1141 HSKYALPSFSYYGFPSSNPVFPSQFLGPGAWGHSGSSGSFEKKPDLHALHNSLSPAYGGA 1200
Query: 1201 EFAELPSQAVPTDAHHPTPHHQQPAYPGPKEYLLPKAPLLHSVSRDPSPFAQSSNCYNRS 1260
EFAELPSQAVPTDAHHPTPHHQQPAYPGPKEYLLPKAPLLHSVSRDPSPFAQSSNCYNRS
Sbjct: 1201 EFAELPSQAVPTDAHHPTPHHQQPAYPGPKEYLLPKAPLLHSVSRDPSPFAQSSNCYNRS 1260
Query: 1261 IKQEPVDPLTQAEPVPRDAGKMGKTPLSEVSQNGGPSHLWGQYSGGPSMSPKRTNGVGGS 1320
IKQEPVDPLTQAEPVPRDAGKMGKTPLSEVSQNGGPSHLWGQYSGGPSMSPKRTNGVGGS
Sbjct: 1261 IKQEPVDPLTQAEPVPRDAGKMGKTPLSEVSQNGGPSHLWGQYSGGPSMSPKRTNGVGGS 1320
Query: 1321 WGVFSSGESPAIVPDKLSSFGASCLAPSHFTDGQWGLFPGEGQQAASHSGGRLRGKPWSP 1380
WGVFSSGESPAIVPDKLSSFGASCLAPSHFTDGQWGLFPGEGQQAASHSGGRLRGKPWSP
Sbjct: 1321 WGVFSSGESPAIVPDKLSSFGASCLAPSHFTDGQWGLFPGEGQQAASHSGGRLRGKPWSP 1380
Query: 1381 CKFGNSTSALAGPSLTEKPWALGAGDFNSALKGSPGFQDKLWNPMKGEEGRIPAAGASQL 1440
CKFGNSTSALAGPSLTEKPWALGAGDFNSALKGSPGFQDKLWNPMKGEEGRIPAAGASQL
Sbjct: 1381 CKFGNSTSALAGPSLTEKPWALGAGDFNSALKGSPGFQDKLWNPMKGEEGRIPAAGASQL 1440
Query: 1441 DRAWQSFGLPLGSSEKLFGALKSEEKLWDPFSLEEGPAEEPPSKGAVKEEKGGGGAEEEE 1500
DRAWQSFGLPLGSSEKLFGALKSEEKLWDPFSLEEGPAEEPPSKGAVKEEKGGGGAEEEE
Sbjct: 1441 DRAWQSFGLPLGSSEKLFGALKSEEKLWDPFSLEEGPAEEPPSKGAVKEEKGGGGAEEEE 1500
Query: 1501 EELWSDSEHNFLDENIGGVAVAPAHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQ 1560
EELWSDSEHNFLDENIGGVAVAPAHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQ
Sbjct: 1501 EELWSDSEHNFLDENIGGVAVAPAHGSILIECARRELHATTPLKKPNRCHPTRISLVFYQ 1560
Query: 1561 HKNLNQPNHGLALWEAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRKWGGTVVAEPQ 1620
HKNLNQPNHGLALWEAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRKWGGTVVAEPQ
Sbjct: 1561 HKNLNQPNHGLALWEAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRKWGGTVVAEPQ 1620
Query: 1621 QKEKKGVVPTRQALAVPTDSAVTVSSYAYTKVTGPYSRWI 1660
QKEKKGVVPTRQALAVPTDSAVTVSSYAYTKVTGPYSRWI
Sbjct: 1621 QKEKKGVVPTRQALAVPTDSAVTVSSYAYTKVTGPYSRWI 1660
>gi|187761317 tet oncogene family member 2 isoform a [Homo sapiens]
Length = 2002
Score = 606 bits (1562), Expect = e-173
Identities = 332/585 (56%), Positives = 401/585 (68%), Gaps = 55/585 (9%)
Query: 617 RSPKQIKIESSGAVTVLS-----------TTCFHSEEGGQEATPTKAENPLTPTLSGFLE 665
+S KQ+K+E SG VTVL+ T + E TPTK L+ F+E
Sbjct: 1049 KSQKQVKVEMSGPVTVLTRQTTAAELDSHTPALEQQTTSSEKTPTK--RTAASVLNNFIE 1106
Query: 666 SPLKYLDTPTKSLLDTPAKRAQAEFPTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELME 725
SP K LDTP K+LLDTP K Q +FP+C CVEQI+EKDEGP+YTHLG+GP VA+IRE+ME
Sbjct: 1107 SPSKLLDTPIKNLLDTPVK-TQYDFPSCRCVEQIIEKDEGPFYTHLGAGPNVAAIREIME 1165
Query: 726 ERYGEKGKAIRIEKVIYTGKEGKSSRGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAV 785
ER+G+KGKAIRIE+VIYTGKEGKSS+GCPIAKWV+RR + EEKLLCLVR RAGH C+ AV
Sbjct: 1166 ERFGQKGKAIRIERVIYTGKEGKSSQGCPIAKWVVRRSSSEEKLLCLVRERAGHTCEAAV 1225
Query: 786 IVILILAWEGIPRSLGDTLYQELTDTLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASF 845
IVILIL WEGIP SL D LY ELT+TLRKYG T+RRC LN++RTCACQG DP TCGASF
Sbjct: 1226 IVILILVWEGIPLSLADKLYSELTETLRKYGTLTNRRCALNEERTCACQGLDPETCGASF 1285
Query: 846 SFGCSWSMYFNGCKYARSKTPRKFRLAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAY 905
SFGCSWSMY+NGCK+ARSK PRKF+L GD+PKEEE L Q+L+T +AP YK+LAP AY
Sbjct: 1286 SFGCSWSMYYNGCKFARSKIPRKFKLLGDDPKEEEKLESHLQNLSTLMAPTYKKLAPDAY 1345
Query: 906 QNQVTNEEIAIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRC 965
NQ+ E A +CRLGLKEGRPF+GVTAC+DFCAHAH+D HN+ NG T+VCTLT+EDNR
Sbjct: 1346 NNQIEYEHRAPECRLGLKEGRPFSGVTACLDFCAHAHRDLHNMQNGSTLVCTLTREDNRE 1405
Query: 966 VGKIPEDEQLHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCR 1025
G PEDEQLHVLPLYK+++ DEFGS E Q K SGAIQVL++F R+VR L EP K+CR
Sbjct: 1406 FGGKPEDEQLHVLPLYKVSDVDEFGSVEAQEEKKRSGAIQVLSSFRRKVRMLAEPVKTCR 1465
Query: 1026 QRQLEARKAAAEK--------KKIQKEKLSTPEKIKQ-----EALELAGITSDPGLSLKG 1072
QR+LEA+KAAAEK K +KEK S P + KQ +A +LA + L L G
Sbjct: 1466 QRKLEAKKAAAEKLSSLENSSNKNEKEK-SAPSRTKQTENASQAKQLAEL-----LRLSG 1519
Query: 1073 GLSQQGLKPS-LKVEPQNHFSSFK-------YSGNAVVESYSVLGNC-------RPSDPY 1117
+ QQ +P L+ +P + + V SYS G+ P PY
Sbjct: 1520 PVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPNPVSPY 1579
Query: 1118 SMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGFPSSNPVFP 1162
NS ++ Y TS F+S + + SY SSNP+ P
Sbjct: 1580 P-NSSHTSDIY----GSTSPMNFYSTSSQAAGSYLN--SSNPMNP 1617
Score = 189 bits (481), Expect = 1e-47
Identities = 100/175 (57%), Positives = 124/175 (70%), Gaps = 11/175 (6%)
Query: 1491 KGGGGAEEEEEELWSDSEHNFLDENIGGVAVAPAHGSILIECARRELHATTPLKKPNRCH 1550
+G E+ +E+WSDSE +FLD +IGGVAVAP HGSILIECA+RELHATTPLK PNR H
Sbjct: 1834 QGVASGAEDNDEVWSDSEQSFLDPDIGGVAVAPTHGSILIECAKRELHATTPLKNPNRNH 1893
Query: 1551 PTRISLVFYQHKNLNQPNHGLALWEAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRK 1610
PTRISLVFYQHK++N+P HGLALWEAKM AE+AR ++EE + G K +GKK K
Sbjct: 1894 PTRISLVFYQHKSMNEPKHGLALWEAKM---AEKAREKEEECEKYGPDYVPQKSHGKKVK 1950
Query: 1611 WGGTVVAEPQQKEKKGVVPTRQALA-----VPTDSAVTVSSYAYTKVTGPYSRWI 1660
AEP + + + ++LA V TDS VT S YA+T+VTGPY+R+I
Sbjct: 1951 ---REPAEPHETSEPTYLRFIKSLAERTMSVTTDSTVTTSPYAFTRVTGPYNRYI 2002
Score = 32.3 bits (72), Expect = 3.9
Identities = 39/133 (29%), Positives = 54/133 (40%), Gaps = 26/133 (19%)
Query: 138 NCDGPECPDY--LEWLEGKI-----KSVVMEGGEERPRLPGPLPPGEAGLPAPSTR---- 186
NC GPE P+ L EGK K++V+ + L P A + A S
Sbjct: 170 NCSGPENPELQILNEQEGKSANYHDKNIVLLKNK------AVLMPNGATVSASSVEHTHG 223
Query: 187 PLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQA- 245
LL + Q P +SIA +K S AI +A +LS + PSH++ Q
Sbjct: 224 ELLEKTLSQYYPD--------CVSIAVQKTTSHINAINSQATNELSCEITHPSHTSGQIN 275
Query: 246 SCPLPEALSPPAP 258
S + PP P
Sbjct: 276 SAQTSNSELPPKP 288
>gi|156139122 CXXC finger 6 [Homo sapiens]
Length = 2136
Score = 507 bits (1305), Expect = e-143
Identities = 279/644 (43%), Positives = 390/644 (60%), Gaps = 42/644 (6%)
Query: 481 EAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDS 540
+ + +FPP+ QI L+ A ++V+ P L S L E + F
Sbjct: 1231 QPKTVFPPLTQIKLQRYPESAEEKVKVEPLDSL-----SLFHLKTESNGKAFTDKAYNSQ 1285
Query: 541 LLPPTQEMRSPSPMT--ALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQ 598
+ + P+T + P + DD++ +F+ + P++P
Sbjct: 1286 VQLTVNANQKAHPLTQPSSPPNQCANVMAGDDQI-----RFQQVVKEQLMHQRLPTLPGI 1340
Query: 599 DPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTP 658
E P PES R+ + + SG +TV+ST EE + T + +
Sbjct: 1341 SHET-----PLPESALTLRN---VNVVCSGGITVVSTKS--EEEVCSSSFGTSEFSTVDS 1390
Query: 659 TLSGFLESPLKYLDTPTKSLLDTPAKRAQAEFPTCDCVEQIVEKDEGPYYTHLGSGPTVA 718
F + + + PTK+L+ +E PTC C++++++KD+GPYYTHLG+GP+VA
Sbjct: 1391 AQKNFNDYAMNFFTNPTKNLVSITK---DSELPTCSCLDRVIQKDKGPYYTHLGAGPSVA 1447
Query: 719 SIRELMEERYGEKGKAIRIEKVIYTGKEGKSSRGCPIAKWVIRRHTLEEKLLCLVRHRAG 778
++RE+ME RYG+KG AIRIE V+YTGKEGKSS GCPIAKWV+RR + EEK+LCLVR R G
Sbjct: 1448 AVREIMENRYGQKGNAIRIEIVVYTGKEGKSSHGCPIAKWVLRRSSDEEKVLCLVRQRTG 1507
Query: 779 HHCQNAVIVILILAWEGIPRSLGDTLYQELTDTLRKY-GNPTSRRCGLNDDRTCACQGKD 837
HHC AV+V+LI+ W+GIP + D LY ELT+ L+ Y G+PT RRC LN++RTC CQG D
Sbjct: 1508 HHCPTAVMVVLIMVWDGIPLPMADRLYTELTENLKSYNGHPTDRRCTLNENRTCTCQGID 1567
Query: 838 PNTCGASFSFGCSWSMYFNGCKYARSKTPRKFRLAGDNPKEEEVLRKSFQDLATEVAPLY 897
P TCGASFSFGCSWSMYFNGCK+ RS +PR+FR+ +P E+ L + Q LAT +AP+Y
Sbjct: 1568 PETCGASFSFGCSWSMYFNGCKFGRSPSPRRFRIDPSSPLHEKNLEDNLQSLATRLAPIY 1627
Query: 898 KRLAPQAYQNQVTNEEIAIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCT 957
K+ AP AYQNQV E +A +CRLG KEGRPF+GVTAC+DFCAH H+D HN+ NG TVVCT
Sbjct: 1628 KQYAPVAYQNQVEYENVARECRLGSKEGRPFSGVTACLDFCAHPHRDIHNMNNGSTVVCT 1687
Query: 958 LTKEDNRCVGKIPEDEQLHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRL 1017
LT+EDNR +G IP+DEQLHVLPLYK+++TDEFGS+E AK+ SGAI+VL PR +R
Sbjct: 1688 LTREDNRSLGVIPQDEQLHVLPLYKLSDTDEFGSKEGMEAKIKSGAIEVLA--PRRKKRT 1745
Query: 1018 ----PEPAKSCRQRQLEARKAAAEKKKIQKEKLSTPEKIKQEALELAGITSDPGLSLKGG 1073
P P ++ + A + + ++K+ + +IK++ S P G
Sbjct: 1746 CFTQPVPRSGKKRAAMMTEVLAHKIRAVEKKPI---PRIKRKNNSTTTNNSKPSSLPTLG 1802
Query: 1074 LSQQGLKPSLKVEPQNHFSSFKYSGNAVVESYSVLGNCRPSDPY 1117
+ + ++P +K E + HF K S N ++YS++ PS P+
Sbjct: 1803 SNTETVQPEVKSETEPHF-ILKSSDN--TKTYSLM----PSAPH 1839
Score = 162 bits (409), Expect = 3e-39
Identities = 86/189 (45%), Positives = 118/189 (62%), Gaps = 16/189 (8%)
Query: 1474 EEGPAEEPPSKGAVKEEKGGGGAEE--EEEELWSDSEHNFLDENIGGVAVAPAHGSILIE 1531
+ A+EPPS + ++ E+ +E WSDSEH FLD NIGGVA+APAHGS+LIE
Sbjct: 1962 QHSEADEPPSDEPLSDDPLSPAEEKLPHIDEYWSDSEHIFLDANIGGVAIAPAHGSVLIE 2021
Query: 1532 CARRELHATTPLKKPNRCHPTRISLVFYQHKNLNQPNHGLALWEAKMKQLAERARARQEE 1591
CARRELHATTP++ PNR HPTR+SLVFYQHKNLN+P HG L K+K A+ A+ ++ +
Sbjct: 2022 CARRELHATTPVEHPNRNHPTRLSLVFYQHKNLNKPQHGFEL--NKIKFEAKEAKNKKMK 2079
Query: 1592 AARLGLGQQEAKLYGKKRKWGGTVVAEPQQKEKKGVVPTRQALAVPTDSAVTVSSYAYTK 1651
A+ +K + + + + +P+ +AL + D+ VTVS YA T
Sbjct: 2080 ASE------------QKDQAANEGPEQSSEVNELNQIPSHKALTLTHDNVVTVSPYALTH 2127
Query: 1652 VTGPYSRWI 1660
V GPY+ W+
Sbjct: 2128 VAGPYNHWV 2136
Score = 46.2 bits (108), Expect = 3e-04
Identities = 23/61 (37%), Positives = 37/61 (60%), Gaps = 2/61 (3%)
Query: 186 RPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQA 245
+P +P P++G P+ S LS+ K++ ++L+ +AIEALTQLS A +S+P
Sbjct: 855 QPKTPENIPSKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQLSEA--PSENSSPSK 912
Query: 246 S 246
S
Sbjct: 913 S 913
Score = 32.0 bits (71), Expect = 5.1
Identities = 54/269 (20%), Positives = 95/269 (35%), Gaps = 37/269 (13%)
Query: 316 PMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQRE 375
P+PR A + ++L I++V K+P +P + +++ P+ P L
Sbjct: 1750 PVPRSGKKRAAMMTEVLAHK---IRAVEKKP--IPRIKRKNNSTTTNNSKPSSLPTLGSN 1804
Query: 376 APTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGW-WPPPSS---P 431
T E + + L+ + K + S P P + ++PG+ W P ++ P
Sbjct: 1805 TETVQPEVKSETEPHFILKSSDNTKTYSLMP-----SAPHPVKEASPGFSWSPKTASATP 1859
Query: 432 VPRLPDRPPK---EKKKKLP--TPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLF 486
P D ++ P T G + AA P + + ++ A +
Sbjct: 1860 APLKNDATASCGFSERSSTPHCTMPSGRLSGANAAAADGPGISQLGEVAPLPTLSAPVME 1919
Query: 487 PPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQ 546
P + G+ P + H P+ L + Q A E A P D
Sbjct: 1920 PLINSEPSTGVTEPLTPHQPNHQPSFLTSPQDLASSPMEEDEQHSEADEPPSD------- 1972
Query: 547 EMRSPSPMTALQPGSTGPLPPADDKLEEL 575
+P S PL PA++KL +
Sbjct: 1973 -----------EPLSDDPLSPAEEKLPHI 1990
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 95.9 bits (237), Expect = 3e-19
Identities = 172/660 (26%), Positives = 230/660 (34%), Gaps = 105/660 (15%)
Query: 9 GDSRQLSASGVPVNGAREPAGPSLLGTGGPWRVDQKPDWEAAPGPAHTARLE-DAHDLVA 67
G S + AS P +G E A P+ + GP + PGP L A + VA
Sbjct: 84 GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 143
Query: 68 FSAVAEAVSSYGALSTRLYETFNREMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALAL 127
EA +S A ++ GP PG A + T + L
Sbjct: 144 RGKATEAPK-------------RSALSAGARRDTSGPTPGTPS-PAMARRSRAAGTEVGL 189
Query: 128 ARHGMKPPNCNCDGPECPDYLEWLEGKIKSVVMEGGEERPRLPGPL----PPGEAGLPAP 183
R P+ P EG KSV E P P P GL P
Sbjct: 190 PRPA---PSARPRPPT--------EGPRKSV-SSASEHSTTEPSPAARRRPSAGGGLQRP 237
Query: 184 STRPLLSSEVPQISPQE------GLPLSQSALSIAKEKNISL-----------QTAIAIE 226
++R L SS P SP G P + + S K K + A A+
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297
Query: 227 ALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDS 286
L+ A P PS T P P+ + P P P S A P+ PP + + +
Sbjct: 298 PLSSSPLATPSPS-GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT 356
Query: 287 SAFPPATPRTEFPEAWGTDTPPATPRSSWPMP---------------RPSPDPMAELEQL 331
PPATP ++ P + T P P S +P PSP ++ L+
Sbjct: 357 LPSPPATPPSQAPPSM-TTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQAT 415
Query: 332 LGSASDYIQSVFKRPEALPTKPKVKVEAPS-SSPAPAPSPVLQREAPTPSSEPDTHQKAQ 390
S +Q+ P + + + +PS + P SP LQ P+S P Q
Sbjct: 416 TSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP-----LQ 470
Query: 391 TALQQHLHHKRS-LFLEQVHDTSFPAPSEPSAP-------------GWWPPPSSPVPRLP 436
T+L + S L + + S A P AP PP P
Sbjct: 471 TSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL 530
Query: 437 DRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEG 496
PP E LP+ A P+ T +AP P + P P +A P P+ E
Sbjct: 531 TTPPLE---NLPSLAPPPLQT-ASAPLTTPHLETP-PCPAPCPLQAPP--SPLTTPPPET 583
Query: 497 LRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTA 556
S A+ QA P P QG +P PP LA P LPP Q SP
Sbjct: 584 PSSIATPPPQAPPALASPPLQG--LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPP 641
Query: 557 LQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFAT 616
L P +T P P A + L + +A F PPS P+Q P + P SP AT
Sbjct: 642 LSPLAT-PSPQAPNAL--AVHLLQAPFSP------PPSPPVQAPFSPPA--SPPVSPSAT 690
Score = 89.4 bits (220), Expect = 3e-17
Identities = 125/469 (26%), Positives = 165/469 (35%), Gaps = 92/469 (19%)
Query: 170 PGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLS----QSALSIAKEKNISLQTAIAI 225
P PP +A L P++ PL +S P +SP PL+ Q+ S+A + +++ +
Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSS-PLTIHPLQALSSLASHSPQAPLSSLIM 509
Query: 226 EALTQLSSALPQPSHSTPQASCPLPE-----ALSPP------APFRSPQSYLRAPSWPVV 274
L SS P PS TP AS P +L+PP AP +P +L P P
Sbjct: 510 PPLETQSSLAP-PSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTP--HLETPPCPAP 566
Query: 275 PPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWP----MPRPSPDPMAELEQ 330
P + AP S P TP E P + T P A P + P +P P P+A
Sbjct: 567 CPLQ----APPS---PLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLAT--- 616
Query: 331 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ 390
P+A P ++AP S PA P L +P +A
Sbjct: 617 -------------PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP----------QAP 653
Query: 391 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP 450
AL HL F P P + PP+SP PP + L P
Sbjct: 654 NALAVHLLQ-----------APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702
Query: 451 AGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP 510
+ A+P + PS P P+ PL P Q+ SP PP
Sbjct: 703 PLQVPPSPPASPPMSPSATPP-------PQAPPPLAAPPLQVPPSPPASPPMSPSATPPP 755
Query: 511 APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD 570
P + +PP P +L P PP Q P A P P PPA
Sbjct: 756 RVPPLLAAPPLQVPPSPPASL----PMSPLAKPPPQ----APPALATPPLQALPSPPAS- 806
Query: 571 KLEELIRQFEAEFGDSFGLPGPPSV---PIQDPENQQTCLPAPESPFAT 616
+A F S LP P P P L P SP A+
Sbjct: 807 ------FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 849
Score = 57.4 bits (137), Expect = 1e-07
Identities = 87/317 (27%), Positives = 114/317 (35%), Gaps = 62/317 (19%)
Query: 165 ERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIA 224
+ P P P PP +A P++ P +SP P SQ+ S+A LQ +
Sbjct: 662 QAPFSPPPSPPVQAPFSPPAS--------PPVSP-SATPPSQAPPSLAAP---PLQVPPS 709
Query: 225 IEALTQLS-SALPQPSHSTPQASCPLPEALSPPA-PFRSPQS--------YLRAPSWPVV 274
A +S SA P P P A+ PL SPPA P SP + L AP V
Sbjct: 710 PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVP 769
Query: 275 P-PEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPA--------TPRSSWPM-----PRP 320
P P +P + P A P P +PPA +P +S PM P P
Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829
Query: 321 SPDPMAELEQLLGSASDYIQSVFKRPEALPTK-PKVKVEAP--SSSPAPAPSPVLQREAP 377
P+ L S + P PT P V P + + AP P P R
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 889
Query: 378 TPSSEPDT--HQKAQTALQQHLHHKRS-------------LFLEQVHDTSF---PAP--- 416
+ S PD H + T+ + L S L H ++ PAP
Sbjct: 890 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLA 949
Query: 417 --SEPSAPGWWPPPSSP 431
P AP WPP + P
Sbjct: 950 FRGAPGAPLPWPPATGP 966
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 91.3 bits (225), Expect = 7e-18
Identities = 167/678 (24%), Positives = 227/678 (33%), Gaps = 141/678 (20%)
Query: 9 GDSRQLSASGVPVNGAREPAGPSLLGTGGPWRVDQKPDWEAAPGPAHTARLE-DAHDLVA 67
G S + AS P +G E A P+ + GP + PGP L A + VA
Sbjct: 84 GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 143
Query: 68 FSAVAEAVSSYGALSTRLYETFNREMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALAL 127
EA +S A ++ GP PG A + T + L
Sbjct: 144 RGKATEAPK-------------RSALSAGARRDTSGPTPGTPS-PAMARRSRAAGTEVGL 189
Query: 128 ARHGMKPPNCNCDGPECPDYLEWLEGKIKSVVMEGGEERPRLPGPL----PPGEAGLPAP 183
R P+ P EG KSV E P P P GL P
Sbjct: 190 PRPA---PSARPRPPT--------EGPRKSV-SSASEHSTTEPSPAARRRPSAGGGLQRP 237
Query: 184 STRPLLSSEVPQISPQE------GLPLSQSALSIAKEKNISL-----------QTAIAIE 226
++R L SS P SP G P + + S K K + A A+
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297
Query: 227 ALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDS 286
L+ A P PS + + P P P S + A P+ PP + + +
Sbjct: 298 PLSSSPLATPSPSAALQSQAPPT----LPATPHSSSLTCQLATPLPLAPPSPSAPPSLQT 353
Query: 287 SAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRP 346
PPATP ++ + G+ T AT +P P P+A P
Sbjct: 354 LPSPPATPPSQATTSLGSPTLQATHSF---LPSPPLSPLAT----------------PPP 394
Query: 347 EALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLE 406
+A P ++AP S PA P L +P +A AL HL
Sbjct: 395 QAPPALALPPLQAPPSPPASPPLSPLATPSP----------QAPNALAVHLLQ------- 437
Query: 407 QVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKP 466
F P P + PP+SP PP + L P + A+P + P
Sbjct: 438 ----APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493
Query: 467 SVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSP---ASQEVQAHPPAPLPASQGSAVPL 523
S P P+ PL P Q+ ++P A+ +QA P PAS P
Sbjct: 494 SATPP-------PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP--PASFPGQAPF 544
Query: 524 PPEPSL---ALFAPSPSRDSLL--PPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQ 578
P SL L P P +L P Q SP LQ P P D +
Sbjct: 545 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS----- 599
Query: 579 FEAEFGDSFGL---PGPPSVPIQDPENQQTCLPAPE----SPFATRSPKQIKIESSGAVT 631
G L PGPP P + P + L P+ S AT +P++++ SG
Sbjct: 600 -----GPRLTLALAPGPPPPPSRSP---SSTLSGPDLAGHSSSATSTPEELRGYDSG--- 648
Query: 632 VLSTTCFHSEEGGQEATP 649
EGG A+P
Sbjct: 649 ---------PEGGAAASP 657
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 88.2 bits (217), Expect = 6e-17
Identities = 136/501 (27%), Positives = 181/501 (36%), Gaps = 87/501 (17%)
Query: 177 EAGLP--APSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSA 234
E GLP APS RP +E P+ S S + S A + S + A LSS+
Sbjct: 177 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 236
Query: 235 ---LPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFA--PDSSAF 289
L P+ S P A P P LR P V PP + ++ A P SS+
Sbjct: 237 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ--VTPPRKDAAPALGPLSSS- 293
Query: 290 PPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEAL 349
P ATP P + P+ P S +P P P ++ LGS + F L
Sbjct: 294 PLATPSPSAPPS------PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF-----L 342
Query: 350 PTKPKVKVEAPSSSPAPAPS-PVLQREAPTPSSEP-----DTHQKAQTALQQHLHHKRSL 403
P+ P + P PA + P LQ P+S P +A AL HL
Sbjct: 343 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ---- 398
Query: 404 FLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPG 463
F P P + PP+SP PP + L P + A+P
Sbjct: 399 -------APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 451
Query: 464 IKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSP---ASQEVQAHPPAPLPASQGSA 520
+ PS P P+ PL P Q+ ++P A+ +QA P PAS
Sbjct: 452 MSPSATPP-------PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP--PASFPGQ 502
Query: 521 VPLPPEPSL---ALFAPSPSRDSLL--PPTQEMRSPSPMTALQPGSTGPLPPADDKLEEL 575
P P SL L P P +L P Q SP LQ P P D +
Sbjct: 503 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS-- 560
Query: 576 IRQFEAEFGDSFGL---PGPPSVPIQDPENQQTCLPAPE----SPFATRSPKQIKIESSG 628
G L PGPP P + P + L P+ S AT +P++++ SG
Sbjct: 561 --------GPRLTLALAPGPPPPPSRSP---SSTLSGPDLAGHSSSATSTPEELRGYDSG 609
Query: 629 AVTVLSTTCFHSEEGGQEATP 649
EGG A+P
Sbjct: 610 ------------PEGGAAASP 618
Score = 86.7 bits (213), Expect = 2e-16
Identities = 178/696 (25%), Positives = 240/696 (34%), Gaps = 158/696 (22%)
Query: 20 PVNGAREPAGPSLLGTGGPWRVDQKPDWEAAPGPAHTARLE-DAHDLVAFSAVAEAVSSY 78
P +G E A P+ + GP + PGP L A + VA EA
Sbjct: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPK-- 143
Query: 79 GALSTRLYETFNREMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCN 138
+S A ++ GP PG A + T + L R P+
Sbjct: 144 -----------RSALSAGARRDTSGPTPGTPS-PAMARRSRAAGTEVGLPRPA---PSAR 188
Query: 139 CDGPECPDYLEWLEGKIKSVVMEGGEERPRLPGPL----PPGEAGLPAPSTRPLLSSEVP 194
P EG KSV E P P P GL P++R L SS P
Sbjct: 189 PRPPT--------EGPRKSV-SSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 239
Query: 195 QISPQE------GLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCP 248
SP G P + + S K K + + + ++ P S+P A+
Sbjct: 240 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT-- 297
Query: 249 LPEALSPPAPFRSPQSYLRAPSWPVVPPEEHS------------SFAPDSSAFPPATPRT 296
P +PP+P +P S PS P PP + + SF P P ATP
Sbjct: 298 -PSPSAPPSP-SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355
Query: 297 EFPEAWGTD------TPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALP 350
+ P A +PPA+P S P+ PSP L A +Q+ F P + P
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLS-PLATPSPQAPNAL------AVHLLQAPFSPPPSPP 408
Query: 351 TKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHD 410
V+AP S PA SP + A PS P SL +
Sbjct: 409 ------VQAPFSPPA---SPPVSPSATPPSQAPP-----------------SLAAPPLQV 442
Query: 411 TSFPAPSEPSAPGWWPPPSSPVPRLPD-----RPPKEKKKKLPTPAGGPVGTEKAA-PG- 463
P S P +P PPP +P P +PP + L TP + + A+ PG
Sbjct: 443 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ 502
Query: 464 --IKPSVRKPIQIKKSRPREAQP-LFPPVRQIVLEGLRSPASQEVQA--HPPAPLPASQG 518
PS P+ + P +A P L P+ Q+ PAS +QA PP P P +
Sbjct: 503 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS---PPASPTLQAPRRPPTPGPDTSV 559
Query: 519 SA-------VPLPP-----EPSLALFAP-----------------------------SPS 537
S P PP PS L P SP
Sbjct: 560 SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 619
Query: 538 RDSLLP---PTQEMRSPSPMTALQ--PGSTGPLPPA--DDKLEELIRQFEAEFGDSFGLP 590
D+ L P R P+P A + PG+ P PPA + L +E E G P
Sbjct: 620 PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE-GPESATP 678
Query: 591 GPPSV-PIQDPENQQTCLPAPESPFA-TRSPKQIKI 624
P ++ P P A A +RSPKQ ++
Sbjct: 679 APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL 714
Score = 54.3 bits (129), Expect = 1e-06
Identities = 109/454 (24%), Positives = 144/454 (31%), Gaps = 93/454 (20%)
Query: 292 ATPRTEFPEAWG--TDTPPATPRSSWPMPRPSP--------------DPMAELEQLLGSA 335
A RT A G T PP +PR P P +P P+AE +G A
Sbjct: 12 AAARTPAARAPGLLTPRPPGSPR---PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
Query: 336 SDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEP------------ 383
+ PE+ P + P +S +P + +P P S P
Sbjct: 69 TI--------PESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 120
Query: 384 -------DTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPS--------APGWWPPP 428
+ + +L DTS P P PS A G
Sbjct: 121 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 180
Query: 429 SSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKA-APGIKPSVRKPIQIKKSR--PREAQPL 485
P P RPP E +K + A TE + A +PS +Q SR A PL
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 240
Query: 486 FPPVRQIVLEGLRSPASQEVQAHPPAP-------------LPASQGSAVPLPPEPSLALF 532
P R G + + AHP P P + +A L P S L
Sbjct: 241 SSPAR----SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 296
Query: 533 APSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGP 592
PSPS P PS T P +T P A L Q F LP P
Sbjct: 297 TPSPS-----APPSPSAPPSLQTLPSPPATPP-SQATTSLGSPTLQATHSF-----LPSP 345
Query: 593 PSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKA 652
P P+ P P++P A P S A LS S +
Sbjct: 346 PLSPL--------ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 397
Query: 653 ENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRA 686
+ P +P S +++P +P S TP +A
Sbjct: 398 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 431
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 87.0 bits (214), Expect = 1e-16
Identities = 140/545 (25%), Positives = 197/545 (36%), Gaps = 63/545 (11%)
Query: 164 EERPRLPGP-----LPPGEAGLPAPSTRPLLSSEVPQI----SPQEGLPLS----QSALS 210
EE P P P PP EA +P L +S +P+ P E PLS +S LS
Sbjct: 445 EESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLS 504
Query: 211 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPP---APFRSPQSYLR 267
E S + + L+ + P P+ TP + P LSPP +P P L
Sbjct: 505 PPPES--SPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL- 561
Query: 268 APSWPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAE 327
P PP E S +P P + P E P PP R P P E
Sbjct: 562 ----PTSPPPEASRLSPPPEESPMSPPPEESP----MSPPPEASRLFPPFEESPLSPPPE 613
Query: 328 LEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAP----APSPVLQREAPTPSSEP 383
L S + PE P P + E+P S P +P PV+ R +P P P
Sbjct: 614 ESPL--SPPPEASRLSPPPEDSPMSPPPE-ESPMSPPPEVSRLSPLPVVSRLSPPPEESP 670
Query: 384 DTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSS----PVPRLPDRP 439
+ ++ R + TS P P++P PP S P+ P P
Sbjct: 671 LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP---PPEDSLMSLPLEESPLLP 727
Query: 440 PKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKP-IQIKKSRPR-EAQPLFPPVRQIVLEGL 497
E+ + P G + P + P +P + + P QP P + + E
Sbjct: 728 LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPH 787
Query: 498 RSPASQEVQAHP-PAPLPASQGSAVP-LPPEPSLALFAPSPSRDSLLPPTQE-MRSPSPM 554
SP ++ P P L S + P L P P +P P L P ++E SP P
Sbjct: 788 LSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPE 847
Query: 555 TA-LQPG-STGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPES 612
+ L P PL P +K E Q A + L PP P P + L P
Sbjct: 848 ESHLSPELEKPPLSPRPEKPPEEPGQCPAP--EELPLFPPPGEPSLSPLLGEPALSEPGE 905
Query: 613 PFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLE---SPLK 669
P + P+++ + SG ++ Q P PL+P ++ SPL
Sbjct: 906 PPLSPLPEELPLSPSGEPSL----------SPQLMPPDPLPPPLSPIITAAAPPALSPLG 955
Query: 670 YLDTP 674
L+ P
Sbjct: 956 ELEYP 960
Score = 72.0 bits (175), Expect = 4e-12
Identities = 105/427 (24%), Positives = 140/427 (32%), Gaps = 101/427 (23%)
Query: 272 PVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQL 331
P++PP E S +P PE T PP R S P P+ E L
Sbjct: 439 PLLPPPEESPLSPP-------------PEESPTSPPPEASRLSPPPEELPASPLPEALHL 485
Query: 332 LGSASDYIQSVFKRP-EALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ 390
RP E P P + S P +P L+ +P E +
Sbjct: 486 ------------SRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALE 533
Query: 391 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPR-LPDRPPKEKKKKLPT 449
T L S P + P +P + P SP P LP PP E + P
Sbjct: 534 TPL------------------SPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPP 575
Query: 450 PAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVL-----EGLRSPASQE 504
P P+ P + S P EA LFPP + L E SP +
Sbjct: 576 PEESPMSPP------------PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEA 623
Query: 505 VQAHPP---APL-PASQGSAVPLPPE-------PSLALFAPSPSRDSLLPPTQEM-RSPS 552
+ PP +P+ P + S + PPE P ++ +P P L PP +E SP
Sbjct: 624 SRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPP 683
Query: 553 P------------MTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDP 600
P T+ P + PP +D L S L P +P+ P
Sbjct: 684 PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM------------SLPLEESPLLPL--P 729
Query: 601 ENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPTL 660
E Q C P E P + P++ + LS Q P P P L
Sbjct: 730 EEPQLC-PRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL 788
Query: 661 SGFLESP 667
S E P
Sbjct: 789 SPQAEGP 795
Score = 65.9 bits (159), Expect = 3e-10
Identities = 138/545 (25%), Positives = 186/545 (34%), Gaps = 70/545 (12%)
Query: 164 EERPRLPGP-----LPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNIS 218
EE P P P PP EA +P +S P+ SP P S +S+ E++
Sbjct: 667 EESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPP-EDSLMSLPLEESPL 725
Query: 219 LQTAIAIEALTQLSSALPQPSHSTPQASCPLPEA--LSPPA--PFRSPQSYLRAPSWPVV 274
L + + P P S P PE LSP A P SPQ P V
Sbjct: 726 LPLPEEPQLCPRSEGPHLSPRPEEPHLS-PRPEEPHLSPQAEEPHLSPQP--EEPCLCAV 782
Query: 275 PPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPD-----PMAELE 329
P E H S + P T+ P +P P P P+ P +E
Sbjct: 783 PEEPHLSPQAEGPHLSPQPEELHLSPQ--TEEPHLSPVPEEPCLSPQPEESHLSPQSEEP 840
Query: 330 QLLGSASD-YIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQK 388
L + ++ ++P P +P+ E P PAP P+ P P +
Sbjct: 841 CLSPRPEESHLSPELEKPPLSP-RPEKPPEEPGQCPAPEELPLF----PPPGEPSLSPLL 895
Query: 389 AQTALQQHLHHKRSLFLEQVHDTSFPAPS---EPSAPGWWPPPSSPVPRLPDRPPKEKKK 445
+ AL + S E++ + PS + P PPP SP+ P
Sbjct: 896 GEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLG 955
Query: 446 KLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFP-PVRQIVLE-------GL 497
+L P G ++ +P P + PI S P EA P PV ++L G
Sbjct: 956 ELEYPFGAKGDSDPESPLAAPILETPI----SPPPEANCTDPEPVPPMILPPSPGSPVGP 1011
Query: 498 RSPASQEVQAHPPAPLPASQGSAVP--LPPE----PSLALFAPSP-----------SRDS 540
SP E PP P Q S VP PP P+L L PSP
Sbjct: 1012 ASPILME--PLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAE 1069
Query: 541 LLPPTQEMRSPSPMTALQPGSTGPLPPADDKLE-------ELIRQFEAEFGDSFGLPGPP 593
L E S AL+P +T PLP L + F D+ L G
Sbjct: 1070 LHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDG-I 1128
Query: 594 SVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAE 653
P PE QT P + SP + E VT + + GQ + + E
Sbjct: 1129 DAPGSQPEPGQT--PGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQE 1186
Query: 654 NPLTP 658
P P
Sbjct: 1187 EPRAP 1191
Score = 62.8 bits (151), Expect = 3e-09
Identities = 78/292 (26%), Positives = 106/292 (36%), Gaps = 31/292 (10%)
Query: 415 APSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQI 474
AP P PP SP+ PP E+ P P + P P+ P +
Sbjct: 432 APLNEEMPLLPPPEESPLS-----PPPEESPTSPPPEASRLSPP---PEELPASPLPEAL 483
Query: 475 KKSRPREAQPLFPPVRQIVLEGL--RSPAS--QEVQAHPPAPLPASQGSAVPLPPEPSLA 530
SRP E PL PP + L SP S +E PP P S PL P P +
Sbjct: 484 HLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEAS 543
Query: 531 LFAPSPSRDSLLPPTQEMRSPSPMTALQ---PGSTGPL--PPADDKLE---ELIRQFEAE 582
+P L PP +E+ + P A + P P+ PP + + E R F
Sbjct: 544 PLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLF-PP 602
Query: 583 FGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEE 642
F +S P P P+ P P PE + P++ + V+ LS S
Sbjct: 603 FEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS-- 660
Query: 643 GGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEFPTCD 694
+P E+PL+P ESP P S L P + + P D
Sbjct: 661 ---RLSPPPEESPLSPPPE---ESPTS--PPPEASRLSPPPEDSPTSPPPED 704
Score = 52.4 bits (124), Expect = 4e-06
Identities = 95/394 (24%), Positives = 140/394 (35%), Gaps = 74/394 (18%)
Query: 142 PECPDYLEWLEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEG 201
P PDY L K P P LPP P PS + + V ++P E
Sbjct: 4601 PTGPDYYSQLLTK------NNLSNPPTPPSSLPP----TPPPSVQQKM---VNGVTPSEE 4647
Query: 202 LPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSHS-TPQASCPLPEALSPP---A 257
L + A++ +L+ +++L L +ALP P H+ T E P
Sbjct: 4648 LGEHPKDAASARDSERALRDTSEVKSL-DLLAALPTPPHNQTEDVRMESDEDSDSPDSIV 4706
Query: 258 PFRSPQSYL--RAPSWPVVPP----EEHSSFAPDSSAFP----PATPRTEFPEAWGTDTP 307
P SP+S L AP +P + +E + +P P P P T+ A G + P
Sbjct: 4707 PASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVP 4766
Query: 308 PATPRSSWPMPRPSP----------------DPMAELEQLLGSASDYIQSVF--KRPEAL 349
P ++W + S M + +LL V + P
Sbjct: 4767 GKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARA 4826
Query: 350 PTKPKV-KVEAPSS--------SPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQH---- 396
T+PK + E P SP P + Q +A P + + L+Q
Sbjct: 4827 GTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAP 4886
Query: 397 ---LHHKRSLFLEQ--VHDTSFPAPSEPS------APGWWPPPSSPVPRLPDRPPKEKKK 445
H + + V S P P EPS AP PP+ P+ LP P E
Sbjct: 4887 EPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP-- 4944
Query: 446 KLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRP 479
P P+ P+ + + KP R P + + SRP
Sbjct: 4945 --PVPSPLPLASSPESARPKPRARPPEEGEDSRP 4976
Score = 49.7 bits (117), Expect = 2e-05
Identities = 116/484 (23%), Positives = 155/484 (32%), Gaps = 88/484 (18%)
Query: 165 ERPRLPGPLPP--GEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTA 222
+RP L +PP G G P P+ P + G P + + LS
Sbjct: 2098 DRPALHLRIPPQPGALGSPPPAAAPTIFI---------GSPTTPAGLS------------ 2136
Query: 223 IAIEALTQLSSALPQPSHSTPQASCP----------LPEALSPPAPFRSPQSYLRAPSWP 272
T L P+ S P P +P + PF +Y P +P
Sbjct: 2137 ------TSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFP 2190
Query: 273 VVPPEEHSSFAPDSS-AFPPATPRTEFPEAWGTD----TPPATPRSSWPMPRPSPDPMA- 326
PP +P + A PP + P A TPP TPR P P P
Sbjct: 2191 TAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCP 2250
Query: 327 ELEQLL---------GSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAP 377
L+ L G AS+ + S E+ K E +SSP+ P + ++P
Sbjct: 2251 SLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSP 2310
Query: 378 TPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPD 437
+ + HL LE F AP P A P SP L
Sbjct: 2311 SSGT--------------HLGG-----LELKTPDVFKAPLTPRASQ--VEPQSPGLGLRP 2349
Query: 438 RPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGL 497
+ P + P+P P + PG S P PR P PP
Sbjct: 2350 QEPPPAQALAPSPPSHP---DIFRPG---SYTDPYAQPPLTPR---PQPPPPESCCALPP 2400
Query: 498 RSPASQEVQAHPPAPLPASQGSAVPLPPEP-SLALFAPSPSRDSLLPPTQEMRSPSPMTA 556
RS S P +P S + PL P P S F PSP P R PS +
Sbjct: 2401 RSLPSDPFSRVPASPQSQSSSQS-PLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQS 2459
Query: 557 LQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPG-PPSVPIQDPENQQTCLPAPESPFA 615
P + PP E + S G G P ++P +P+ + P
Sbjct: 2460 RDPFAPLHKPPRPQPPEVAFKAGSLAH-TSLGAGGFPAALPAGPAGELHAKVPSGQPPNF 2518
Query: 616 TRSP 619
RSP
Sbjct: 2519 VRSP 2522
Score = 44.3 bits (103), Expect = 0.001
Identities = 110/491 (22%), Positives = 173/491 (35%), Gaps = 60/491 (12%)
Query: 168 RLPGPLPPGEAGLPAPSTRPLL--SSEVPQISPQEG-LPLSQSALSIAKEKNISLQTAIA 224
RL P PP ++R L+ S Q +P G LPL Q + +++ + T++
Sbjct: 2771 RLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMR 2830
Query: 225 IEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPV----VPPEEHS 280
A++ + P P PL +S P P + P+ P +
Sbjct: 2831 F-AMSARFPSTPGPELGRQALGSPLA-GISTRLP--GPGEPVPGPAGPAQFIELRHNVQK 2886
Query: 281 SFAPDSSAFP----PATPR----TEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLL 332
P + FP P PR +E P + S P +PS P EL L
Sbjct: 2887 GLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSL 2946
Query: 333 GSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEP--DTHQKAQ 390
+ LPT ++ PSS+ P+P+ P +P D A
Sbjct: 2947 HPTPH------TKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAH 3000
Query: 391 TALQ--QHLHH----------KRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDR 438
AL+ + L H L + +T+ P + + + P L
Sbjct: 3001 KALEDDEELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTG 3060
Query: 439 PPKE---KKKKLPTPAGGPVGTEKAAPGIK-----PSVRKPIQIKKSRPREAQPLFPPVR 490
K+ + +L A E G++ P R P S PR A L P V+
Sbjct: 3061 DKKDIFNEHLRLVESANEKAEREALLRGVEPGPLGPEERPPPAADASEPRLASVL-PEVK 3119
Query: 491 QIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRS 550
V EG R P+ + P PA +++ L +P ++ SRD+ + S
Sbjct: 3120 PKVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMG---SRDTRMGTGPFSSS 3176
Query: 551 PSPMTALQPGSTG--------PLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPEN 602
G+TG P P + L+ +FE E G + LPG P+ + +
Sbjct: 3177 GHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFELESG-ALTLPGGPAASGDELDK 3235
Query: 603 QQTCLPAPESP 613
++ L A E P
Sbjct: 3236 MESSLVASELP 3246
Score = 42.7 bits (99), Expect = 0.003
Identities = 45/170 (26%), Positives = 65/170 (38%), Gaps = 19/170 (11%)
Query: 524 PPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPL----PPADDKLEELIRQF 579
PPEP P+ D+L Q +T++QP GPL P +L Q
Sbjct: 374 PPEPG---DTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQL 430
Query: 580 EAEFGDSFG-LPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCF 638
EA + LP P P+ P + P PE+ + P+++ LS
Sbjct: 431 EAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLE 490
Query: 639 HSEEGGQEATPTKAENPLTP-----TLSGFLESPLK-YLDTPTKSLLDTP 682
S +P E+PL+P S ESPL ++P L+TP
Sbjct: 491 ES-----PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETP 535
Score = 41.2 bits (95), Expect = 0.008
Identities = 80/318 (25%), Positives = 108/318 (33%), Gaps = 36/318 (11%)
Query: 162 GGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQT 221
GG+ L P P GE+ + L + P P L S S + L+T
Sbjct: 2265 GGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPN-LGFVDSPSSGTHLGGLELKT 2323
Query: 222 AIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSS 281
+A P+ S PQ+ L P P P + APS P P
Sbjct: 2324 PDVFKA-----PLTPRASQVEPQSP---GLGLRPQEP---PPAQALAPSPPSHPDIFRPG 2372
Query: 282 FAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQS 341
D A PP TPR + P PP + + P PS DP + + S S
Sbjct: 2373 SYTDPYAQPPLTPRPQPP-------PPESCCALPPRSLPS-DPFSRVPASPQSQSSSQSP 2424
Query: 342 VFKRP---EAL---PTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQ 395
+ RP EA P P+ + P S P PS R+ P +P Q + A +
Sbjct: 2425 LTPRPLSAEAFCPSPVTPRFQSPDPYSRP---PSRPQSRDPFAPLHKPPRPQPPEVAFK- 2480
Query: 396 HLHHKRSLFLEQVHDTSFPA--PSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGG 453
SL + FPA P+ P+ PS P P P+P
Sbjct: 2481 ----AGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRF 2536
Query: 454 PVGTEKAAPGIKPSVRKP 471
P +KP V +P
Sbjct: 2537 TFPQAVGEPSLKPPVPQP 2554
Score = 37.7 bits (86), Expect = 0.093
Identities = 58/218 (26%), Positives = 76/218 (34%), Gaps = 44/218 (20%)
Query: 474 IKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFA 533
+ +P+E PL + + G VQ P P ++ +PL P P + +
Sbjct: 401 VTSMQPKEPGPLQCEAKPLGKAG--------VQLEPQLEAPLNE--EMPLLPPPEESPLS 450
Query: 534 PSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPP 593
P P PP + R P L P S PLP A L R E +S P P
Sbjct: 451 PPPEESPTSPPPEASRLSPPPEEL-PAS--PLPEA----LHLSRPLE----ESPLSPPPE 499
Query: 594 SVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAE 653
P+ P P ESP SP + S T LS P
Sbjct: 500 ESPLSPPPESSPFSPLEESPL---SPPEESPPSPALETPLS--------------PPPEA 542
Query: 654 NPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEFP 691
+PL+P F ESP L P + L +P A P
Sbjct: 543 SPLSPP---FEESP---LSPPPEELPTSPPPEASRLSP 574
Score = 35.0 bits (79), Expect = 0.61
Identities = 84/345 (24%), Positives = 123/345 (35%), Gaps = 44/345 (12%)
Query: 170 PGPLPPGEAGLPAPST-RPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEAL 228
PG + G P RP+ ++ PQ P + P+ QS + + + + +
Sbjct: 4145 PGSMTQNLLGPQQPMLERPMQNNTGPQ--PPKPGPVLQSGQGLP---GVGIMPTVG-QLR 4198
Query: 229 TQLSSAL---PQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPD 285
QL L PQ H +PQ L +AL + Q+ + P P P +S
Sbjct: 4199 AQLQGVLAKNPQLRHLSPQQQQQL-QALLMQRQLQQSQAVRQTP--PYQEPGTQTSPLQG 4255
Query: 286 SSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKR 345
P P+ A PR P P+P +LG
Sbjct: 4256 LLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPV---------H 4306
Query: 346 PEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFL 405
P P+ P+ E S P+PS L EA P + P T K Q + + S
Sbjct: 4307 PTPPPSSPQ---EPKRPSQLPSPSSQLPTEAQLPPTHPGT-PKPQGPTLEPPPGRVSPAA 4362
Query: 406 EQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLP---TPAGGPVGTEKAAP 462
Q+ DT F P W PP + L + E+ +P G V E +
Sbjct: 4363 AQLADTLFSKGLGP-----WDPPDN----LAETQKPEQSSLVPGHLDQVNGQVVPEASQL 4413
Query: 463 GIKPSVR-KPIQI-KKSRPREA--QPLFPP--VRQIVLEGLRSPA 501
IK R +P + +S REA +P+ P ++L G RS A
Sbjct: 4414 SIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEA 4458
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 85.9 bits (211), Expect = 3e-16
Identities = 113/472 (23%), Positives = 161/472 (34%), Gaps = 46/472 (9%)
Query: 237 QPSHSTPQASCPLPEALSPPAPFR-SPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPR 295
+P+ +TP+ P +P P +P + AP+ P P + ++ PA
Sbjct: 223 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 282
Query: 296 TEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRP-----EALP 350
T+ P T + P TP+ P P P E + + + K P E P
Sbjct: 283 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 342
Query: 351 TKPKVKVEAPSSSPAPA----PSPVLQRE-APTPSSEPDTHQKAQTALQQHLHHKRSLFL 405
T PK PAP P+P +E APT + EP + A +
Sbjct: 343 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA-PTTTKSAPTTTK 401
Query: 406 EQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRP-PKEKKKKLPTPAGGPVGTEKAAPG- 463
E T+ AP+ P P P P P P P KK PT P T P
Sbjct: 402 EPAPTTTKSAPTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 460
Query: 464 ---IKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAP-LPASQGS 519
KP+ P + + P+E P P +P + E PAP P
Sbjct: 461 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE----KPAPTTPEELAP 516
Query: 520 AVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQF 579
P P P+ P+P+ P + P+P T +P T P PA +E
Sbjct: 517 TTPEEPTPTTP-EEPAPTTPKAAAPNTP-KEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 574
Query: 580 EAEFGDSFGLPGPPSVPIQDPENQQTCLPAPE--SPFATRSPKQIKIESSGAVTVLSTTC 637
G +++P PAP+ +P T+ P + T T
Sbjct: 575 P---------KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT-- 623
Query: 638 FHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAE 689
+ +E PT + P T G + LK PT TP K A E
Sbjct: 624 --APTTPKEPAPTTPKEPAPTTPKGTAPTTLKE-PAPT-----TPKKPAPKE 667
Score = 65.5 bits (158), Expect = 4e-10
Identities = 103/418 (24%), Positives = 147/418 (35%), Gaps = 77/418 (18%)
Query: 167 PRLPGPLPPGEAGLPAPST----RPLLSSEVPQISPQEGLPLS-QSALSIAKEKNISLQT 221
P+ P P P E PAP+T P + E +P+E P + +SA + KE +
Sbjct: 353 PKKPAPTTPKE---PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 409
Query: 222 AIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSS 281
+ + +P+ +TP+ P P PAP + AP+ P P
Sbjct: 410 SAPTTPKEPSPTTTKEPAPTTPKE--PAPTTPKKPAPTTPKEP---APTTPKEP------ 458
Query: 282 FAPDSSAFP-PATPRTEFPEAWGTDTPPATPRSSWPM------PRPSPDPMAELEQLLGS 334
AP ++ P P TP+ P +T P TP+ P P P + L
Sbjct: 459 -APTTTKKPAPTTPKEPAPTT-PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 516
Query: 335 ASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQ 394
+ + E PT PK AP++ PAP+ + APT EP +TA
Sbjct: 517 TTPEEPTPTTPEEPAPTTPKAA--APNTPKEPAPTTP-KEPAPTTPKEPAPTTPKETA-- 571
Query: 395 QHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGP 454
P + +AP P+ P+ P PKE PT P
Sbjct: 572 -------------------PTTPKGTAPTTLKEPAPTTPKKP--APKELA---PTTTKEP 607
Query: 455 VGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPL- 513
T KP+ P + P+E P P + PA + P L
Sbjct: 608 TSTTCD----KPAPTTPKGTAPTTPKEPAPTTP----------KEPAPTTPKGTAPTTLK 653
Query: 514 -PASQGSAVPLPPE--PSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPA 568
PA P P E P+ S + D P T + +P T +P T P PA
Sbjct: 654 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP--KETAPTTPKEPAPTTPKKPA 709
Score = 52.4 bits (124), Expect = 4e-06
Identities = 82/405 (20%), Positives = 127/405 (31%), Gaps = 71/405 (17%)
Query: 272 PVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAE---- 327
P P + + D+ F TP T + T P + PRPS P ++
Sbjct: 80 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 139
Query: 328 ----------LEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAP 377
+E + ++ S + + K +E S+ S VL + P
Sbjct: 140 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--P 197
Query: 378 TPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPD 437
TP +E T A T ++ P P+ P P P P P
Sbjct: 198 TPKAETTTKGPALTTPKE------------------PTPTTPKEPAS-TTPKEPTPTTIK 238
Query: 438 RPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGL 497
P K+ PT T K+AP P P K+ P + P
Sbjct: 239 SAPTTPKEPAPT-------TTKSAP-TTPKEPAPTTTKEPAPTTPKEPAPTTT------- 283
Query: 498 RSPA---SQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPM 554
+ PA ++ P P P + P P+ P+ + P + P+P
Sbjct: 284 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 343
Query: 555 TALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPF 614
T +P T P PA +E P ++P T P+P +P
Sbjct: 344 TPKEPAPTAPKKPAPTTPKE-----------------PAPTTPKEPAPTTTKEPSPTTP- 385
Query: 615 ATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPT 659
+P K + TT + +E +PT + P T
Sbjct: 386 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 430
Score = 47.4 bits (111), Expect = 1e-04
Identities = 67/298 (22%), Positives = 104/298 (34%), Gaps = 50/298 (16%)
Query: 167 PRLPGPLPPGEAGLPAPSTRPLLSSEVPQ----ISPQEGLPLSQSALSIAKEKNISLQTA 222
P P L P PAP+T L+ P+ +P+E P + A + K + T
Sbjct: 492 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 551
Query: 223 IAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVP-PEEHSS 281
T +P+ +TP+ + P + P + P AP+ P P P+E
Sbjct: 552 KEPAPTTP-----KEPAPTTPKETAPTTPKGTAPTTLKEP-----APTTPKKPAPKE--- 598
Query: 282 FAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQS 341
AP ++ P +T + T P TP+ P P P + + +
Sbjct: 599 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 658
Query: 342 VFKRP---EALPTKPK--------------VKVEAPSSSPAPAPSPVLQREAPTPSSEPD 384
K+P E PT K K AP++ PAP+ + TP + P
Sbjct: 659 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 718
Query: 385 THQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKE 442
T + T K + + D S P S + P P+ + PKE
Sbjct: 719 TTSEVSTPTTT----KEPTTIHKSPDESTPELS-----------AEPTPKALENSPKE 761
Score = 41.6 bits (96), Expect = 0.006
Identities = 43/226 (19%), Positives = 77/226 (34%), Gaps = 10/226 (4%)
Query: 167 PRLPGPLPPGEAGLPAPS-TRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAI 225
P+ P P P E P T P E +P++ P + + + + +
Sbjct: 559 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 618
Query: 226 EALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVP-PEEHSSFAP 284
+ +P+ +TP+ P + P + P AP+ P P P+E AP
Sbjct: 619 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP-----APTTPKKPAPKE---LAP 670
Query: 285 DSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFK 344
++ P +T + +T P TP+ P P P ++ + K
Sbjct: 671 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 730
Query: 345 RPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ 390
P + P S+ P P +E P+++ K +
Sbjct: 731 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE 776
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 85.9 bits (211), Expect = 3e-16
Identities = 113/472 (23%), Positives = 161/472 (34%), Gaps = 46/472 (9%)
Query: 237 QPSHSTPQASCPLPEALSPPAPFR-SPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPR 295
+P+ +TP+ P +P P +P + AP+ P P + ++ PA
Sbjct: 264 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 323
Query: 296 TEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRP-----EALP 350
T+ P T + P TP+ P P P E + + + K P E P
Sbjct: 324 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 383
Query: 351 TKPKVKVEAPSSSPAPA----PSPVLQRE-APTPSSEPDTHQKAQTALQQHLHHKRSLFL 405
T PK PAP P+P +E APT + EP + A +
Sbjct: 384 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA-PTTTKSAPTTTK 442
Query: 406 EQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRP-PKEKKKKLPTPAGGPVGTEKAAPG- 463
E T+ AP+ P P P P P P P KK PT P T P
Sbjct: 443 EPAPTTTKSAPTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 501
Query: 464 ---IKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAP-LPASQGS 519
KP+ P + + P+E P P +P + E PAP P
Sbjct: 502 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE----KPAPTTPEELAP 557
Query: 520 AVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQF 579
P P P+ P+P+ P + P+P T +P T P PA +E
Sbjct: 558 TTPEEPTPTTP-EEPAPTTPKAAAPNTP-KEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 615
Query: 580 EAEFGDSFGLPGPPSVPIQDPENQQTCLPAPE--SPFATRSPKQIKIESSGAVTVLSTTC 637
G +++P PAP+ +P T+ P + T T
Sbjct: 616 P---------KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT-- 664
Query: 638 FHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAE 689
+ +E PT + P T G + LK PT TP K A E
Sbjct: 665 --APTTPKEPAPTTPKEPAPTTPKGTAPTTLKE-PAPT-----TPKKPAPKE 708
Score = 65.5 bits (158), Expect = 4e-10
Identities = 103/418 (24%), Positives = 147/418 (35%), Gaps = 77/418 (18%)
Query: 167 PRLPGPLPPGEAGLPAPST----RPLLSSEVPQISPQEGLPLS-QSALSIAKEKNISLQT 221
P+ P P P E PAP+T P + E +P+E P + +SA + KE +
Sbjct: 394 PKKPAPTTPKE---PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 450
Query: 222 AIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSS 281
+ + +P+ +TP+ P P PAP + AP+ P P
Sbjct: 451 SAPTTPKEPSPTTTKEPAPTTPKE--PAPTTPKKPAPTTPKEP---APTTPKEP------ 499
Query: 282 FAPDSSAFP-PATPRTEFPEAWGTDTPPATPRSSWPM------PRPSPDPMAELEQLLGS 334
AP ++ P P TP+ P +T P TP+ P P P + L
Sbjct: 500 -APTTTKKPAPTTPKEPAPTT-PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 557
Query: 335 ASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQ 394
+ + E PT PK AP++ PAP+ + APT EP +TA
Sbjct: 558 TTPEEPTPTTPEEPAPTTPKAA--APNTPKEPAPTTP-KEPAPTTPKEPAPTTPKETA-- 612
Query: 395 QHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGP 454
P + +AP P+ P+ P PKE PT P
Sbjct: 613 -------------------PTTPKGTAPTTLKEPAPTTPKKP--APKELA---PTTTKEP 648
Query: 455 VGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPL- 513
T KP+ P + P+E P P + PA + P L
Sbjct: 649 TSTTCD----KPAPTTPKGTAPTTPKEPAPTTP----------KEPAPTTPKGTAPTTLK 694
Query: 514 -PASQGSAVPLPPE--PSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPA 568
PA P P E P+ S + D P T + +P T +P T P PA
Sbjct: 695 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP--KETAPTTPKEPAPTTPKKPA 750
Score = 52.4 bits (124), Expect = 4e-06
Identities = 82/405 (20%), Positives = 127/405 (31%), Gaps = 71/405 (17%)
Query: 272 PVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAE---- 327
P P + + D+ F TP T + T P + PRPS P ++
Sbjct: 121 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 180
Query: 328 ----------LEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAP 377
+E + ++ S + + K +E S+ S VL + P
Sbjct: 181 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--P 238
Query: 378 TPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPD 437
TP +E T A T ++ P P+ P P P P P
Sbjct: 239 TPKAETTTKGPALTTPKE------------------PTPTTPKEPAS-TTPKEPTPTTIK 279
Query: 438 RPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGL 497
P K+ PT T K+AP P P K+ P + P
Sbjct: 280 SAPTTPKEPAPT-------TTKSAP-TTPKEPAPTTTKEPAPTTPKEPAPTTT------- 324
Query: 498 RSPA---SQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPM 554
+ PA ++ P P P + P P+ P+ + P + P+P
Sbjct: 325 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 384
Query: 555 TALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPF 614
T +P T P PA +E P ++P T P+P +P
Sbjct: 385 TPKEPAPTAPKKPAPTTPKE-----------------PAPTTPKEPAPTTTKEPSPTTP- 426
Query: 615 ATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPT 659
+P K + TT + +E +PT + P T
Sbjct: 427 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 471
Score = 47.4 bits (111), Expect = 1e-04
Identities = 67/298 (22%), Positives = 104/298 (34%), Gaps = 50/298 (16%)
Query: 167 PRLPGPLPPGEAGLPAPSTRPLLSSEVPQ----ISPQEGLPLSQSALSIAKEKNISLQTA 222
P P L P PAP+T L+ P+ +P+E P + A + K + T
Sbjct: 533 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 592
Query: 223 IAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVP-PEEHSS 281
T +P+ +TP+ + P + P + P AP+ P P P+E
Sbjct: 593 KEPAPTTP-----KEPAPTTPKETAPTTPKGTAPTTLKEP-----APTTPKKPAPKE--- 639
Query: 282 FAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQS 341
AP ++ P +T + T P TP+ P P P + + +
Sbjct: 640 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 699
Query: 342 VFKRP---EALPTKPK--------------VKVEAPSSSPAPAPSPVLQREAPTPSSEPD 384
K+P E PT K K AP++ PAP+ + TP + P
Sbjct: 700 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 759
Query: 385 THQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKE 442
T + T K + + D S P S + P P+ + PKE
Sbjct: 760 TTSEVSTPTTT----KEPTTIHKSPDESTPELS-----------AEPTPKALENSPKE 802
Score = 41.6 bits (96), Expect = 0.006
Identities = 43/226 (19%), Positives = 77/226 (34%), Gaps = 10/226 (4%)
Query: 167 PRLPGPLPPGEAGLPAPS-TRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAI 225
P+ P P P E P T P E +P++ P + + + + +
Sbjct: 600 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 659
Query: 226 EALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVP-PEEHSSFAP 284
+ +P+ +TP+ P + P + P AP+ P P P+E AP
Sbjct: 660 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP-----APTTPKKPAPKE---LAP 711
Query: 285 DSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFK 344
++ P +T + +T P TP+ P P P ++ + K
Sbjct: 712 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 771
Query: 345 RPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ 390
P + P S+ P P +E P+++ K +
Sbjct: 772 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE 817
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 85.9 bits (211), Expect = 3e-16
Identities = 113/472 (23%), Positives = 161/472 (34%), Gaps = 46/472 (9%)
Query: 237 QPSHSTPQASCPLPEALSPPAPFR-SPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPR 295
+P+ +TP+ P +P P +P + AP+ P P + ++ PA
Sbjct: 316 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 375
Query: 296 TEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRP-----EALP 350
T+ P T + P TP+ P P P E + + + K P E P
Sbjct: 376 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 435
Query: 351 TKPKVKVEAPSSSPAPA----PSPVLQRE-APTPSSEPDTHQKAQTALQQHLHHKRSLFL 405
T PK PAP P+P +E APT + EP + A +
Sbjct: 436 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA-PTTTKSAPTTTK 494
Query: 406 EQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRP-PKEKKKKLPTPAGGPVGTEKAAPG- 463
E T+ AP+ P P P P P P P KK PT P T P
Sbjct: 495 EPAPTTTKSAPTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 553
Query: 464 ---IKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAP-LPASQGS 519
KP+ P + + P+E P P +P + E PAP P
Sbjct: 554 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE----KPAPTTPEELAP 609
Query: 520 AVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQF 579
P P P+ P+P+ P + P+P T +P T P PA +E
Sbjct: 610 TTPEEPTPTTP-EEPAPTTPKAAAPNTP-KEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 667
Query: 580 EAEFGDSFGLPGPPSVPIQDPENQQTCLPAPE--SPFATRSPKQIKIESSGAVTVLSTTC 637
G +++P PAP+ +P T+ P + T T
Sbjct: 668 P---------KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT-- 716
Query: 638 FHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAE 689
+ +E PT + P T G + LK PT TP K A E
Sbjct: 717 --APTTPKEPAPTTPKEPAPTTPKGTAPTTLKE-PAPT-----TPKKPAPKE 760
Score = 65.5 bits (158), Expect = 4e-10
Identities = 103/418 (24%), Positives = 147/418 (35%), Gaps = 77/418 (18%)
Query: 167 PRLPGPLPPGEAGLPAPST----RPLLSSEVPQISPQEGLPLS-QSALSIAKEKNISLQT 221
P+ P P P E PAP+T P + E +P+E P + +SA + KE +
Sbjct: 446 PKKPAPTTPKE---PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502
Query: 222 AIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSS 281
+ + +P+ +TP+ P P PAP + AP+ P P
Sbjct: 503 SAPTTPKEPSPTTTKEPAPTTPKE--PAPTTPKKPAPTTPKEP---APTTPKEP------ 551
Query: 282 FAPDSSAFP-PATPRTEFPEAWGTDTPPATPRSSWPM------PRPSPDPMAELEQLLGS 334
AP ++ P P TP+ P +T P TP+ P P P + L
Sbjct: 552 -APTTTKKPAPTTPKEPAPTT-PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 609
Query: 335 ASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQ 394
+ + E PT PK AP++ PAP+ + APT EP +TA
Sbjct: 610 TTPEEPTPTTPEEPAPTTPKAA--APNTPKEPAPTTP-KEPAPTTPKEPAPTTPKETA-- 664
Query: 395 QHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGP 454
P + +AP P+ P+ P PKE PT P
Sbjct: 665 -------------------PTTPKGTAPTTLKEPAPTTPKKP--APKELA---PTTTKEP 700
Query: 455 VGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPL- 513
T KP+ P + P+E P P + PA + P L
Sbjct: 701 TSTTCD----KPAPTTPKGTAPTTPKEPAPTTP----------KEPAPTTPKGTAPTTLK 746
Query: 514 -PASQGSAVPLPPE--PSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPA 568
PA P P E P+ S + D P T + +P T +P T P PA
Sbjct: 747 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP--KETAPTTPKEPAPTTPKKPA 802
Score = 52.4 bits (124), Expect = 4e-06
Identities = 82/405 (20%), Positives = 127/405 (31%), Gaps = 71/405 (17%)
Query: 272 PVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAE---- 327
P P + + D+ F TP T + T P + PRPS P ++
Sbjct: 173 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 232
Query: 328 ----------LEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAP 377
+E + ++ S + + K +E S+ S VL + P
Sbjct: 233 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--P 290
Query: 378 TPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPD 437
TP +E T A T ++ P P+ P P P P P
Sbjct: 291 TPKAETTTKGPALTTPKE------------------PTPTTPKEPAS-TTPKEPTPTTIK 331
Query: 438 RPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGL 497
P K+ PT T K+AP P P K+ P + P
Sbjct: 332 SAPTTPKEPAPT-------TTKSAP-TTPKEPAPTTTKEPAPTTPKEPAPTTT------- 376
Query: 498 RSPA---SQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPM 554
+ PA ++ P P P + P P+ P+ + P + P+P
Sbjct: 377 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 436
Query: 555 TALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPF 614
T +P T P PA +E P ++P T P+P +P
Sbjct: 437 TPKEPAPTAPKKPAPTTPKE-----------------PAPTTPKEPAPTTTKEPSPTTP- 478
Query: 615 ATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPT 659
+P K + TT + +E +PT + P T
Sbjct: 479 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 523
Score = 47.4 bits (111), Expect = 1e-04
Identities = 67/298 (22%), Positives = 104/298 (34%), Gaps = 50/298 (16%)
Query: 167 PRLPGPLPPGEAGLPAPSTRPLLSSEVPQ----ISPQEGLPLSQSALSIAKEKNISLQTA 222
P P L P PAP+T L+ P+ +P+E P + A + K + T
Sbjct: 585 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 644
Query: 223 IAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVP-PEEHSS 281
T +P+ +TP+ + P + P + P AP+ P P P+E
Sbjct: 645 KEPAPTTP-----KEPAPTTPKETAPTTPKGTAPTTLKEP-----APTTPKKPAPKE--- 691
Query: 282 FAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQS 341
AP ++ P +T + T P TP+ P P P + + +
Sbjct: 692 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 751
Query: 342 VFKRP---EALPTKPK--------------VKVEAPSSSPAPAPSPVLQREAPTPSSEPD 384
K+P E PT K K AP++ PAP+ + TP + P
Sbjct: 752 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 811
Query: 385 THQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKE 442
T + T K + + D S P S + P P+ + PKE
Sbjct: 812 TTSEVSTPTTT----KEPTTIHKSPDESTPELS-----------AEPTPKALENSPKE 854
Score = 41.6 bits (96), Expect = 0.006
Identities = 43/226 (19%), Positives = 77/226 (34%), Gaps = 10/226 (4%)
Query: 167 PRLPGPLPPGEAGLPAPS-TRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAI 225
P+ P P P E P T P E +P++ P + + + + +
Sbjct: 652 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 711
Query: 226 EALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVP-PEEHSSFAP 284
+ +P+ +TP+ P + P + P AP+ P P P+E AP
Sbjct: 712 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP-----APTTPKKPAPKE---LAP 763
Query: 285 DSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFK 344
++ P +T + +T P TP+ P P P ++ + K
Sbjct: 764 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 823
Query: 345 RPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ 390
P + P S+ P P +E P+++ K +
Sbjct: 824 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE 869
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 85.9 bits (211), Expect = 3e-16
Identities = 113/472 (23%), Positives = 161/472 (34%), Gaps = 46/472 (9%)
Query: 237 QPSHSTPQASCPLPEALSPPAPFR-SPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPR 295
+P+ +TP+ P +P P +P + AP+ P P + ++ PA
Sbjct: 357 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 416
Query: 296 TEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRP-----EALP 350
T+ P T + P TP+ P P P E + + + K P E P
Sbjct: 417 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 476
Query: 351 TKPKVKVEAPSSSPAPA----PSPVLQRE-APTPSSEPDTHQKAQTALQQHLHHKRSLFL 405
T PK PAP P+P +E APT + EP + A +
Sbjct: 477 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA-PTTTKSAPTTTK 535
Query: 406 EQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRP-PKEKKKKLPTPAGGPVGTEKAAPG- 463
E T+ AP+ P P P P P P P KK PT P T P
Sbjct: 536 EPAPTTTKSAPTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 594
Query: 464 ---IKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAP-LPASQGS 519
KP+ P + + P+E P P +P + E PAP P
Sbjct: 595 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE----KPAPTTPEELAP 650
Query: 520 AVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQF 579
P P P+ P+P+ P + P+P T +P T P PA +E
Sbjct: 651 TTPEEPTPTTP-EEPAPTTPKAAAPNTP-KEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 708
Query: 580 EAEFGDSFGLPGPPSVPIQDPENQQTCLPAPE--SPFATRSPKQIKIESSGAVTVLSTTC 637
G +++P PAP+ +P T+ P + T T
Sbjct: 709 P---------KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT-- 757
Query: 638 FHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAE 689
+ +E PT + P T G + LK PT TP K A E
Sbjct: 758 --APTTPKEPAPTTPKEPAPTTPKGTAPTTLKE-PAPT-----TPKKPAPKE 801
Score = 65.5 bits (158), Expect = 4e-10
Identities = 103/418 (24%), Positives = 147/418 (35%), Gaps = 77/418 (18%)
Query: 167 PRLPGPLPPGEAGLPAPST----RPLLSSEVPQISPQEGLPLS-QSALSIAKEKNISLQT 221
P+ P P P E PAP+T P + E +P+E P + +SA + KE +
Sbjct: 487 PKKPAPTTPKE---PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543
Query: 222 AIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSS 281
+ + +P+ +TP+ P P PAP + AP+ P P
Sbjct: 544 SAPTTPKEPSPTTTKEPAPTTPKE--PAPTTPKKPAPTTPKEP---APTTPKEP------ 592
Query: 282 FAPDSSAFP-PATPRTEFPEAWGTDTPPATPRSSWPM------PRPSPDPMAELEQLLGS 334
AP ++ P P TP+ P +T P TP+ P P P + L
Sbjct: 593 -APTTTKKPAPTTPKEPAPTT-PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 650
Query: 335 ASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQ 394
+ + E PT PK AP++ PAP+ + APT EP +TA
Sbjct: 651 TTPEEPTPTTPEEPAPTTPKAA--APNTPKEPAPTTP-KEPAPTTPKEPAPTTPKETA-- 705
Query: 395 QHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGP 454
P + +AP P+ P+ P PKE PT P
Sbjct: 706 -------------------PTTPKGTAPTTLKEPAPTTPKKP--APKELA---PTTTKEP 741
Query: 455 VGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPL- 513
T KP+ P + P+E P P + PA + P L
Sbjct: 742 TSTTCD----KPAPTTPKGTAPTTPKEPAPTTP----------KEPAPTTPKGTAPTTLK 787
Query: 514 -PASQGSAVPLPPE--PSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPA 568
PA P P E P+ S + D P T + +P T +P T P PA
Sbjct: 788 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP--KETAPTTPKEPAPTTPKKPA 843
Score = 52.4 bits (124), Expect = 4e-06
Identities = 82/405 (20%), Positives = 127/405 (31%), Gaps = 71/405 (17%)
Query: 272 PVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAE---- 327
P P + + D+ F TP T + T P + PRPS P ++
Sbjct: 214 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 273
Query: 328 ----------LEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAP 377
+E + ++ S + + K +E S+ S VL + P
Sbjct: 274 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--P 331
Query: 378 TPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPD 437
TP +E T A T ++ P P+ P P P P P
Sbjct: 332 TPKAETTTKGPALTTPKE------------------PTPTTPKEPAS-TTPKEPTPTTIK 372
Query: 438 RPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGL 497
P K+ PT T K+AP P P K+ P + P
Sbjct: 373 SAPTTPKEPAPT-------TTKSAP-TTPKEPAPTTTKEPAPTTPKEPAPTTT------- 417
Query: 498 RSPA---SQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPM 554
+ PA ++ P P P + P P+ P+ + P + P+P
Sbjct: 418 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 477
Query: 555 TALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPF 614
T +P T P PA +E P ++P T P+P +P
Sbjct: 478 TPKEPAPTAPKKPAPTTPKE-----------------PAPTTPKEPAPTTTKEPSPTTP- 519
Query: 615 ATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPT 659
+P K + TT + +E +PT + P T
Sbjct: 520 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 564
Score = 47.4 bits (111), Expect = 1e-04
Identities = 67/298 (22%), Positives = 104/298 (34%), Gaps = 50/298 (16%)
Query: 167 PRLPGPLPPGEAGLPAPSTRPLLSSEVPQ----ISPQEGLPLSQSALSIAKEKNISLQTA 222
P P L P PAP+T L+ P+ +P+E P + A + K + T
Sbjct: 626 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 685
Query: 223 IAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVP-PEEHSS 281
T +P+ +TP+ + P + P + P AP+ P P P+E
Sbjct: 686 KEPAPTTP-----KEPAPTTPKETAPTTPKGTAPTTLKEP-----APTTPKKPAPKE--- 732
Query: 282 FAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQS 341
AP ++ P +T + T P TP+ P P P + + +
Sbjct: 733 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 792
Query: 342 VFKRP---EALPTKPK--------------VKVEAPSSSPAPAPSPVLQREAPTPSSEPD 384
K+P E PT K K AP++ PAP+ + TP + P
Sbjct: 793 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 852
Query: 385 THQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKE 442
T + T K + + D S P S + P P+ + PKE
Sbjct: 853 TTSEVSTPTTT----KEPTTIHKSPDESTPELS-----------AEPTPKALENSPKE 895
Score = 41.6 bits (96), Expect = 0.006
Identities = 43/226 (19%), Positives = 77/226 (34%), Gaps = 10/226 (4%)
Query: 167 PRLPGPLPPGEAGLPAPS-TRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAI 225
P+ P P P E P T P E +P++ P + + + + +
Sbjct: 693 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 752
Query: 226 EALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVP-PEEHSSFAP 284
+ +P+ +TP+ P + P + P AP+ P P P+E AP
Sbjct: 753 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP-----APTTPKKPAPKE---LAP 804
Query: 285 DSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFK 344
++ P +T + +T P TP+ P P P ++ + K
Sbjct: 805 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 864
Query: 345 RPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ 390
P + P S+ P P +E P+++ K +
Sbjct: 865 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE 910
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 84.7 bits (208), Expect = 7e-16
Identities = 134/557 (24%), Positives = 184/557 (33%), Gaps = 99/557 (17%)
Query: 167 PRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIE 226
P P PP G PA + P +S P +P K T +
Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPS-------------PKGSPAATPLPKG 1055
Query: 227 ALTQLSSALPQPSH--STPQAS-CPLPEALSPPAPFRSPQ--SYLRAPSWPVV-PPEEHS 280
A T ++ LP P +TP P P A +PP+P P S AP P PP
Sbjct: 1056 APTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKG 1115
Query: 281 SFAPDSSAFPPATPRTEFPEAWG----------TDTPPATPRS-----SWPMPRPSPDPM 325
A P TP P G TP ATP S + P P+ +P
Sbjct: 1116 GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175
Query: 326 AELEQLL--GSASDYIQSVFKRPEALPTKPKVKVE------APSSSPAPAPSPVLQREAP 377
A G A+ + P A P PK + AP++ A PSP P
Sbjct: 1176 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1235
Query: 378 TPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPP---------- 427
+P P T + + + P P+ P PP
Sbjct: 1236 SPKGAPTTPAATPPS-------------PKGGPATPPPKGAPTPPAATPPSLKGGLATPP 1282
Query: 428 ------PSSPVPRLP-DRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPR 480
P+ P P P K PTP + K +PG P P + P
Sbjct: 1283 HKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS 1342
Query: 481 -EAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRD 539
+ P P G +P+S+E PPA P+ +G PP P PSP D
Sbjct: 1343 PKGTPTLPATTPSSKGGPTTPSSKEGPT-PPAATPSHKGGPAMTPPSPKRGPAIPSPKGD 1401
Query: 540 SLLP---PTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLP-GPPSV 595
P P ++P+ + +T P D + + + P G P+
Sbjct: 1402 PTSPAVIPLSPKKAPATPVTREGAAT---PSKGDLTPPAVTPVSLKKAPATSAPKGGPAT 1458
Query: 596 PIQ--DPENQQTCLPAPESPFATRSPKQIKIESS-----------GAVTVLSTTCFHSEE 642
P DP P+P+ P A PKQ+ SS GA T+ + +E
Sbjct: 1459 PSSKGDPTLPAVTPPSPKEPPA---PKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKE 1515
Query: 643 GGQEATPTKAENPLTPT 659
ATP+ +P+ PT
Sbjct: 1516 --VPATPSSRRDPIAPT 1530
Score = 83.2 bits (204), Expect = 2e-15
Identities = 131/513 (25%), Positives = 183/513 (35%), Gaps = 92/513 (17%)
Query: 152 EGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGL--PLSQSAL 209
+G + + +G P P P G P+P P + P SP+ GL P + A
Sbjct: 1183 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP-SPKGGLATPSPKGAP 1241
Query: 210 SIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQA-----------SCPLPEALSPPAP 258
+ S + A T P P +TP + P P ++PP+P
Sbjct: 1242 TTPAATPPSPKGGPA----TPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297
Query: 259 FRSPQSY--LRAPSWP-VVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSS- 314
P + AP+ P PP S P P P GT T PAT SS
Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357
Query: 315 ----WPMPRPSPDPMAELEQLLGSASDYIQS-----VFKRPEALPTKPKVKVEAPSSSPA 365
P + P P A G + S P+ PT P V +P +PA
Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA 1417
Query: 366 PAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFP--APSEPSAPG 423
+PV + A TP S+ D A T + L++ TS P P+ PS+ G
Sbjct: 1418 ---TPVTREGAATP-SKGDLTPPAVTPVS----------LKKAPATSAPKGGPATPSSKG 1463
Query: 424 --WWPPPSSPVPRLPDRPPK-------EKKKKLPTPAGGPV------GTEKAAPGIKPSV 468
P + P P+ P P + +K P P G P + K P S
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSR 1523
Query: 469 RKPIQ-----IKKSRPREAQP---LFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSA 520
R PI + K P P L PP V ++PA + P P+S+ ++
Sbjct: 1524 RDPIAPTATLLSKKTPATLAPKEALIPPA-MTVPSPKKTPAIPTPKEAPAT--PSSKEAS 1580
Query: 521 VPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFE 580
P PS APSP ++ L+PP + SPSP A P + PP+ +K
Sbjct: 1581 SPPAVTPSTYKGAPSP-KELLIPPA--VTSPSPKEAPTPPAV--TPPSPEK--------- 1626
Query: 581 AEFGDSFGLPGPPSVPIQDPENQQTCLPAPESP 613
P P P P + +P SP
Sbjct: 1627 -----GPATPAPKGTPTSPPVTPSSLKDSPTSP 1654
Score = 82.4 bits (202), Expect = 3e-15
Identities = 152/626 (24%), Positives = 227/626 (36%), Gaps = 92/626 (14%)
Query: 161 EGGEERPRLP-GPLPPGEAGLPA----PSTRPLLSSEVPQISPQEGLPLSQSALSIAKEK 215
+GG P GP PP A P+ P+ P P I +G P S + + ++ +K
Sbjct: 1357 KGGPTTPSSKEGPTPP--AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK 1414
Query: 216 NISLQTAIAIEALTQLSSALPQPSHSTPQASCP--LPEALSPPAPFRSPQ--SYLRAPSW 271
+T+ +A P TP A P L +A + AP P S P+
Sbjct: 1415 -------APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467
Query: 272 PVV-PPEEHSSFAPD---SSAFPPATPRTEFPEAWGTDTPPA----TPRSSWPMPRPSPD 323
P V PP AP +S+ P P T P G T PA +P+ P D
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSSSPKKAPAT--PAPMGAPTLPAVIPSSPKEVPATPSSRRD 1525
Query: 324 PMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAP-TPSSE 382
P+A LL + + P+ P + V +P +PA P+P +EAP TPSS+
Sbjct: 1526 PIAPTATLLSKKTPATLA----PKEALIPPAMTVPSPKKTPA-IPTP---KEAPATPSSK 1577
Query: 383 PDTHQKAQT-ALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPK 441
+ A T + + + L + PA + PS P +P P P
Sbjct: 1578 EASSPPAVTPSTYKGAPSPKELLIP-------PAVTSPS------PKEAPTPPAVTPPSP 1624
Query: 442 EKKKKLPTPAGGPVGTEKAAPGIKPSVRKPI-----------QIKKSRPREAQPLFPPVR 490
EK P P G P +K S P Q K P + P ++
Sbjct: 1625 EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP--TALK 1682
Query: 491 QIVLEGLRSPASQEVQAHPPAPLPASQGSAV---PLPPEPS--------LALFAPSPSRD 539
++++ +P S + P P ++ S+ P+ P+PS L+ AP+P
Sbjct: 1683 EVLV--APAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP--- 1737
Query: 540 SLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQD 599
LLP ++ + GPL P + K + E LP P S +
Sbjct: 1738 -LLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFE----KVLPKPESASVSA 1792
Query: 600 PENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLT-- 657
+ LP SP T PKQ + SS + + S + + E P P++
Sbjct: 1793 APSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGG 1852
Query: 658 -PTLSGFLESPLKY---LDTPTKSLLDTPAKRAQAEFPTCDCVEQIVEKDEGPYYTHLGS 713
P S + P + PT S K + D E + E +E
Sbjct: 1853 VPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQ 1912
Query: 714 GPTVASIRELMEERYGEKGKAIRIEK 739
+A+ E+ EE K K R EK
Sbjct: 1913 QAQLAAAAEIDEEPV-SKAKQSRSEK 1937
Score = 72.4 bits (176), Expect = 3e-12
Identities = 136/591 (23%), Positives = 196/591 (33%), Gaps = 116/591 (19%)
Query: 104 PRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEWLEGKIKSVVMEGG 163
P P G G++ +D + ALA P C + + + G
Sbjct: 737 PSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTE-----------DSGASATASSKG 785
Query: 164 EERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGL--PLSQSALSIAKEKNISLQT 221
P P G + P P +P L P+S S E ++S Q
Sbjct: 786 TLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQG 845
Query: 222 AIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSS 281
+ A T P+ +P+ + P P A++P +P +PP+E +
Sbjct: 846 SKDSPATTH------SPTPPSPKGA-PTPSAVTP-----------LSPKGVTLPPKETPT 887
Query: 282 FAPDSSAFPPATPRTEFP-EAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQ 340
+ + FP P T P +A ++P+ + P P P +
Sbjct: 888 PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASP------------- 934
Query: 341 SVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHK 400
P+ PT P +P PA PSP + APTP + K
Sbjct: 935 ----SPKGAPTPPAATPPSPKGGPA-TPSP---KWAPTPPAATPPSPKG----------- 975
Query: 401 RSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKA 460
P+ PS G PP++ P P K PTP + K
Sbjct: 976 --------------GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG 1021
Query: 461 APGIKPSVRKPIQIKKSRPREAQPLFP---PVRQIVLEGLRSPASQEVQAHPPAP-LPAS 516
+P P + S P A P P P + +G + + + + P P+
Sbjct: 1022 SPAATPFPK-----GASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSL 1076
Query: 517 QGSAVP---LPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLE 573
+G+ P PP P PSP + + +PP SP A P P PA
Sbjct: 1077 KGAPTPPAATPPSPKGGPATPSP-KGAPMPPAATPPSPKGGLATPPHKGAPTTPA----- 1130
Query: 574 ELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVL 633
GL PP P P P+P+ AT PK GA T
Sbjct: 1131 ------ATPPSPKGGLATPP--PKGAPTTPAATPPSPKGGLATPPPK-------GAPTTP 1175
Query: 634 STTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPT-KSLLDTPA 683
+ T S +GG ATP+ P TP + SP L TP+ K TPA
Sbjct: 1176 AATP-PSPKGGL-ATPSPKGAPTTPAATP--PSPKGGLATPSPKGAPTTPA 1222
Score = 35.0 bits (79), Expect = 0.61
Identities = 63/260 (24%), Positives = 96/260 (36%), Gaps = 37/260 (14%)
Query: 440 PKEKKKKLPTPAGGPVGTEKAAPGIK---PSVRKPIQIKKSRPREAQPLFPPVRQIVLEG 496
P+ + LP + V PG P P Q S +A P FP I
Sbjct: 19 PQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASP-FPSPSTIASTP 77
Query: 497 LRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTA 556
L P Q +S G+A+PL P F P+ + P + SP
Sbjct: 78 LEVPFPQ-----------SSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPT 126
Query: 557 LQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFAT 616
L+ + P A L Q + F + L PPSV + + + T L AP +P
Sbjct: 127 LKGTPSSSAPLALVALAPHSVQKSSAFPPNL-LTSPPSVAVAESGSVIT-LSAPIAPSEP 184
Query: 617 RS-----PKQIKIESSGAVT---VLSTTCFH------SEEGGQEATPTKAENPLTPTLSG 662
++ P ++ G + ++ST +H S + G + P TPT +
Sbjct: 185 KTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLP-----QTTPTTTL 239
Query: 663 FLESPLKYLDTPTKSLLDTP 682
+ SP + DT S+L +P
Sbjct: 240 AIASP-QVKDTTISSVLISP 258
Score = 35.0 bits (79), Expect = 0.61
Identities = 93/422 (22%), Positives = 140/422 (33%), Gaps = 66/422 (15%)
Query: 169 LPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIA---- 224
L P PG L P + P S Q P + + + ISL + +A
Sbjct: 255 LISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQ 314
Query: 225 -----IEALTQLS-SALPQPS-------HSTPQASCPLPEALSPPAPFRSPQSYLRAPSW 271
++ L Q SAL P+ HS+ AS P ++ PP P R+ ++
Sbjct: 315 SSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAF 374
Query: 272 PVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQL 331
PVV P D P+T S P S + +A L
Sbjct: 375 PVVAPS--------------------------VDKGPSTISSITCSPSGSLN-VATSFSL 407
Query: 332 LGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQT 391
+ S ++S P ++ V + ++P +P APT + E T
Sbjct: 408 SPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPM 467
Query: 392 ALQQHLHHKRSLFLEQVHDTS----FPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKL 447
+ S + + TS AP P P + +P P P E K L
Sbjct: 468 S---------SGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNL 518
Query: 448 PTPAGGPVGTEKAAPGIKPSVR----KPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQ 503
P+ T+K + S+ P Q + ++ P P+ Q + SP+ Q
Sbjct: 519 PSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKD--PTVLPLVQAAPK--NSPSFQ 574
Query: 504 EVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTG 563
+ P PL A EP L + P+ S S L + P S G
Sbjct: 575 STSSSPEIPLSPEATLAKKSLGEP-LPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAG 633
Query: 564 PL 565
PL
Sbjct: 634 PL 635
Score = 31.2 bits (69), Expect = 8.8
Identities = 120/527 (22%), Positives = 170/527 (32%), Gaps = 126/527 (23%)
Query: 157 SVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKN 216
SV G+ P LP P P AP PL S Q SP P + S E
Sbjct: 33 SVTAALGQPGPTLPPPCSP------APQQCPL--SAANQASP---FPSPSTIASTPLEV- 80
Query: 217 ISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPP 276
Q SS P + P+A LP + PP SP + A P++ P
Sbjct: 81 ----------PFPQSSSGTALPLGTAPEAPTFLPNLIGPPI---SPAALALAS--PMIAP 125
Query: 277 E---EHSSFAP------------DSSAFPP----ATPRTEFPEAWGTDT-----PPATPR 312
SS AP SSAFPP + P E+ T P+ P+
Sbjct: 126 TLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK 185
Query: 313 SSW--------PMPRPSPDPMAELEQL----LGSASDYIQSVFKRPEALPT------KPK 354
++ P P+ +P P + + + + V P+ PT P+
Sbjct: 186 TNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQ 245
Query: 355 VK------------------VEAPSSSPAPAPSPVLQREAPTPSSE---PDTHQKAQTAL 393
VK ++ P S PA T S + P+T +L
Sbjct: 246 VKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISL 305
Query: 394 QQH---LHHKRSLFLEQVHDTSFPAPSEP----------SAPGWWPPPSSPVPRLPDRPP 440
H LH ++ + T A S+P S +P S +P LP R
Sbjct: 306 GSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSR-- 363
Query: 441 KEKKKKLP-TPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLF--PPVRQIVLEGL 497
+ +P T A PV G PS I S F P ++L+
Sbjct: 364 ---NEVVPATVAAFPVVAPSVDKG--PSTISSITCSPSGSLNVATSFSLSPTTSLILK-- 416
Query: 498 RSPASQEVQAHPP--APLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMT 555
+S H P A +P S PL + A + + S P++
Sbjct: 417 ---SSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPIS 473
Query: 556 ALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPEN 602
++P S L A +E Q L P S P+ DPE+
Sbjct: 474 NIEPTSPAALVMAPVAPKEPSTQVATT------LRIPVSPPLPDPED 514
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 78.6 bits (192), Expect = 5e-14
Identities = 127/518 (24%), Positives = 176/518 (33%), Gaps = 99/518 (19%)
Query: 199 QEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAP 258
QE L ++SA + S+++ + ++ + S S S + P S
Sbjct: 514 QEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRS---- 569
Query: 259 FRSPQSYLRAPSWPVVPPEEHSSFA-------PDSSAFPPATPRTEFPEAWGTDTP---- 307
+S S + + +W E SS A P +S PP +P+ + + P
Sbjct: 570 -QSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPL 628
Query: 308 PATPRSSWPMPRPSPDPMAELEQ--------------------LLGSASDYIQSVFKRP- 346
P P P P P P P L L +AS + ++FK P
Sbjct: 629 PPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPT 688
Query: 347 ----EALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTA--LQQHLHHK 400
++ KP++ V P P P P PTP S + A A L Q
Sbjct: 689 PPVMQSQSVKPQILVPPNGVVPPPPPPP----PPPTPGSAMAQLKPAPCAPSLPQFSAPP 744
Query: 401 RSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAG----GPVG 456
L + QV + AP P PPP P P P PPK +P P PV
Sbjct: 745 PPLKIHQVQHITQVAPPTPP-----PPPPIPAPLPPQAPPK-PLVTIPAPTSTKTVAPVV 798
Query: 457 TEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP----AP 512
T+ A P P V P + + + P P PP + + P Q A PP +P
Sbjct: 799 TQAAPPTPTPPV-PPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSP 857
Query: 513 LP------ASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSP--SPMTALQPGSTGP 564
+P ASQ P PP P P+ + P P P + P P
Sbjct: 858 VPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFP 917
Query: 565 LPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKI 624
PP + L P PP P+ P P P T SP K
Sbjct: 918 PPPPESSLV---------------FPPPPPSPVPAP---------PPPPPPTASPTPDKS 953
Query: 625 ESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPTLSG 662
S G T + S GG++ PT N + SG
Sbjct: 954 GSPGKKTSKT-----SSPGGKKPPPTPQRNSSIKSSSG 986
Score = 78.6 bits (192), Expect = 5e-14
Identities = 126/499 (25%), Positives = 168/499 (33%), Gaps = 127/499 (25%)
Query: 167 PRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIE 226
P LP P PP P P P P + P + P + SA + + T ++
Sbjct: 626 PPLPPPPPPPPPPPPPPPPPP------PPL-PSQSAPSAGSAAPMF----VKYSTITRLQ 674
Query: 227 ALTQLSSAL-PQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFA-- 283
+Q S AL P+ Q+ P+ L PP P P P PP S+ A
Sbjct: 675 NASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPP------PPPPPPPPTPGSAMAQL 728
Query: 284 ---------PDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGS 334
P SA PP + T P TP P P P P P+
Sbjct: 729 KPAPCAPSLPQFSAPPPPLKIHQVQHI--TQVAPPTP----PPPPPIPAPL--------- 773
Query: 335 ASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQ 394
P P KP V + AP+S+ AP V Q PTP+
Sbjct: 774 -----------PPQAPPKPLVTIPAPTSTKTVAPV-VTQAAPPTPTPPVP---------- 811
Query: 395 QHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKK--LPTPAG 452
PA +P+ P + PPS P P +P PP K++ P
Sbjct: 812 -------------------PAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPP 852
Query: 453 GPVGTEKAAPGIKPSVRKPIQIKKSRP-----REAQPLFPPVRQIVLEGLRSPASQEVQA 507
P+ PSV K I + P E+QPL P + + PA +
Sbjct: 853 SPLSP-------VPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQS--PPAVKAKPK 903
Query: 508 HPPAPLPASQGSAVPLPPEPSLALFAPSPSR-DSLLPPTQEMRSPSPMTALQPGST---- 562
P+ +P P PPE SL P PS + PP SP+P + PG
Sbjct: 904 WQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKT 963
Query: 563 ----GPLPPADDKLEELIRQFEAEFGDSFGLPGPPSV---------PIQDPENQQTCLPA 609
G PP + I+ + G P PSV P + + LP
Sbjct: 964 SSPGGKKPPPTPQRNSSIK---SSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPP 1020
Query: 610 PESPFATRSPKQIKIESSG 628
P +P PK K+ SG
Sbjct: 1021 PAAP-----PKPGKLNLSG 1034
Score = 33.5 bits (75), Expect = 1.8
Identities = 38/156 (24%), Positives = 56/156 (35%), Gaps = 29/156 (18%)
Query: 172 PLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAK------EKNISLQTAIAI 225
P PP P P P +S P S G S+++ K ++N S++++
Sbjct: 929 PPPPSPVPAPPPPPPPT-ASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGA 987
Query: 226 E-------ALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSW------- 271
E ++ L S P+ S + LP +PP P + S + P
Sbjct: 988 EHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVS 1047
Query: 272 ---PVVPPEEHSSFA-----PDSSAFPPATPRTEFP 299
PV+ S P S FPP P TE P
Sbjct: 1048 AKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELP 1083
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 76.6 bits (187), Expect = 2e-13
Identities = 111/448 (24%), Positives = 155/448 (34%), Gaps = 93/448 (20%)
Query: 151 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS 210
L ++++ + GG E LP P + + A S S E P P G P S
Sbjct: 590 LSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDP------S 643
Query: 211 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS 270
+E+N LP+ + P+ LP PP F PQ +PS
Sbjct: 644 PPQERN------------------LPEGTERPPKLCSSLPGQGPPPYVFMYPQG---SPS 682
Query: 271 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSP---DPMAE 327
P P + +A A PPATP PP R S + RP P D E
Sbjct: 683 SPAPGPPPGAPWAFSYLAGPPATP----------PDPPRPKRRSHSLSRPGPTEGDAEGE 732
Query: 328 LEQLLGSASDYIQSVFKRP---EALPTKPKVKVEAPSSSPA-------------PAPSPV 371
E +GS ++ +RP + T P V +P P P P
Sbjct: 733 AEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPK 792
Query: 372 LQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSP 431
PS EP ++ + +R E P+ PS P P
Sbjct: 793 RLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSE---------PAGPSEP--------P 835
Query: 432 VPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQ 491
P P P + +++ P P G P + G+ + + IK+ RP+ A P PP
Sbjct: 836 GPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQ-RPKPAGP--PPRET 892
Query: 492 IVLEGL-----------RSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDS 540
V GL R P +E + A L SA P P P L +P+P
Sbjct: 893 PVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAP---LPSPTPGES- 948
Query: 541 LLPPTQEMRSPSPMTALQPGSTGPLPPA 568
PP + P P + G PL P+
Sbjct: 949 --PPASSLPQPEPSSLPAQGVPTPLAPS 974
Score = 42.7 bits (99), Expect = 0.003
Identities = 58/230 (25%), Positives = 81/230 (35%), Gaps = 23/230 (10%)
Query: 358 EAPSSSPAPA-PSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAP 416
E P+ P+ PSP +R P + P K ++L +F+ S PAP
Sbjct: 631 EQPAPQPSGGDPSPPQERNLPEGTERPP---KLCSSLPGQ-GPPPYVFMYPQGSPSSPAP 686
Query: 417 SEPSAPGW------WPPPSSPVPRLPDRPPKEKKKKLPTP------AGGPVGTEKAAPGI 464
P W PP + P P P R + PT A GPVG+ +
Sbjct: 687 GPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGS--Y 744
Query: 465 KPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLP 524
R+P +S P P +S A + + PP P P S
Sbjct: 745 ATLTRRP---GRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPS 801
Query: 525 PEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEE 574
PEP +P P + P + + P+ + PG P PA D EE
Sbjct: 802 PEPPPLDESPGPKEGATGPRRRTLSEPAGPSE-PPGPPAPAGPASDTEEE 850
Score = 35.0 bits (79), Expect = 0.61
Identities = 76/301 (25%), Positives = 108/301 (35%), Gaps = 61/301 (20%)
Query: 91 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW 150
R +S AG + P P G ++ +E+ + PP+ G P + E
Sbjct: 823 RTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGT--------PPSRGSSGEGLP-FAE- 872
Query: 151 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQ--EGLPLSQSA 208
EG + ++RP+ GP PP E +P L S+ + P+ E PL +
Sbjct: 873 -EGNLTI------KQRPKPAGP-PPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTAL 924
Query: 209 LSIAKEKNISLQTAIAIEALTQLSSA---LPQPSHSTPQASCPLPEALSPPAPFRSPQSY 265
L A + + T +A P P S P +S P PE S PA P
Sbjct: 925 L------------AFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQ-GVPTPL 971
Query: 266 LRAPSW-PVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDT-PPATPRSSWPMP--RPS 321
+P+ P VPP P A R W +T PPA P + +P +
Sbjct: 972 APSPAMQPPVPP------CPGPGLESSAASR------WNGETEPPAAPAALLKVPGAGTA 1019
Query: 322 PDPMA-ELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPS 380
P P++ QL S + RP P P S+ P QR T S
Sbjct: 1020 PKPVSVACTQLAFSGPKLAPRLGPRPVPPP--------RPESTGTVGPGQAQQRLEQTSS 1071
Query: 381 S 381
S
Sbjct: 1072 S 1072
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 76.6 bits (187), Expect = 2e-13
Identities = 111/448 (24%), Positives = 155/448 (34%), Gaps = 93/448 (20%)
Query: 151 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALS 210
L ++++ + GG E LP P + + A S S E P P G P S
Sbjct: 672 LSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDP------S 725
Query: 211 IAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS 270
+E+N LP+ + P+ LP PP F PQ +PS
Sbjct: 726 PPQERN------------------LPEGTERPPKLCSSLPGQGPPPYVFMYPQG---SPS 764
Query: 271 WPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSP---DPMAE 327
P P + +A A PPATP PP R S + RP P D E
Sbjct: 765 SPAPGPPPGAPWAFSYLAGPPATP----------PDPPRPKRRSHSLSRPGPTEGDAEGE 814
Query: 328 LEQLLGSASDYIQSVFKRP---EALPTKPKVKVEAPSSSPA-------------PAPSPV 371
E +GS ++ +RP + T P V +P P P P
Sbjct: 815 AEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPK 874
Query: 372 LQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSP 431
PS EP ++ + +R E P+ PS P P
Sbjct: 875 RLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSE---------PAGPSEP--------P 917
Query: 432 VPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQ 491
P P P + +++ P P G P + G+ + + IK+ RP+ A P PP
Sbjct: 918 GPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQ-RPKPAGP--PPRET 974
Query: 492 IVLEGL-----------RSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDS 540
V GL R P +E + A L SA P P P L +P+P
Sbjct: 975 PVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAP---LPSPTPGES- 1030
Query: 541 LLPPTQEMRSPSPMTALQPGSTGPLPPA 568
PP + P P + G PL P+
Sbjct: 1031 --PPASSLPQPEPSSLPAQGVPTPLAPS 1056
Score = 42.7 bits (99), Expect = 0.003
Identities = 58/230 (25%), Positives = 81/230 (35%), Gaps = 23/230 (10%)
Query: 358 EAPSSSPAPA-PSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAP 416
E P+ P+ PSP +R P + P K ++L +F+ S PAP
Sbjct: 713 EQPAPQPSGGDPSPPQERNLPEGTERPP---KLCSSLPGQ-GPPPYVFMYPQGSPSSPAP 768
Query: 417 SEPSAPGW------WPPPSSPVPRLPDRPPKEKKKKLPTP------AGGPVGTEKAAPGI 464
P W PP + P P P R + PT A GPVG+ +
Sbjct: 769 GPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGS--Y 826
Query: 465 KPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLP 524
R+P +S P P +S A + + PP P P S
Sbjct: 827 ATLTRRP---GRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPS 883
Query: 525 PEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEE 574
PEP +P P + P + + P+ + PG P PA D EE
Sbjct: 884 PEPPPLDESPGPKEGATGPRRRTLSEPAGPSE-PPGPPAPAGPASDTEEE 932
Score = 35.0 bits (79), Expect = 0.61
Identities = 76/301 (25%), Positives = 108/301 (35%), Gaps = 61/301 (20%)
Query: 91 REMSREAGNNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEW 150
R +S AG + P P G ++ +E+ + PP+ G P + E
Sbjct: 905 RTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGT--------PPSRGSSGEGLP-FAE- 954
Query: 151 LEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQ--EGLPLSQSA 208
EG + ++RP+ GP PP E +P L S+ + P+ E PL +
Sbjct: 955 -EGNLTI------KQRPKPAGP-PPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTAL 1006
Query: 209 LSIAKEKNISLQTAIAIEALTQLSSA---LPQPSHSTPQASCPLPEALSPPAPFRSPQSY 265
L A + + T +A P P S P +S P PE S PA P
Sbjct: 1007 L------------AFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQ-GVPTPL 1053
Query: 266 LRAPSW-PVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDT-PPATPRSSWPMP--RPS 321
+P+ P VPP P A R W +T PPA P + +P +
Sbjct: 1054 APSPAMQPPVPP------CPGPGLESSAASR------WNGETEPPAAPAALLKVPGAGTA 1101
Query: 322 PDPMA-ELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPS 380
P P++ QL S + RP P P S+ P QR T S
Sbjct: 1102 PKPVSVACTQLAFSGPKLAPRLGPRPVPPP--------RPESTGTVGPGQAQQRLEQTSS 1153
Query: 381 S 381
S
Sbjct: 1154 S 1154
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 75.9 bits (185), Expect = 3e-13
Identities = 93/409 (22%), Positives = 130/409 (31%), Gaps = 60/409 (14%)
Query: 170 PGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALT 229
P P P LP P+T P + P P + + I+ T
Sbjct: 1406 PSPPPTSTTTLP-PTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTT-T 1463
Query: 230 QLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPS----WPVVPPEEHSSFAPD 285
+ P P +TP P SPP + PS P+ PP ++ P
Sbjct: 1464 PPPTTTPSPPTTTPSPPTTTP---SPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPT 1520
Query: 286 SSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKR 345
++ PP T T TPP T S P P P + + +
Sbjct: 1521 TTPSPPTTT---------TTTPPPTTTPSPPTTTPITPPTST------TTLPPTTTPSPP 1565
Query: 346 PEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFL 405
P T P +P ++ P+P P + P P++ P
Sbjct: 1566 PTTTTTPPPTTTPSPPTTTTPSP-PTITTTTPPPTTTPSP-------------------- 1604
Query: 406 EQVHDTSFPAPSEPSAPGWWP--PPSS----PVPRLPDRPPKEKKKKLPTPAGGPVGTEK 459
T+ P + PS P P PP+S P P PP PT P T
Sbjct: 1605 PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT 1664
Query: 460 AAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGS 519
+P I + P S P P P +P+S P S
Sbjct: 1665 PSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTP--------S 1716
Query: 520 AVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPA 568
+ P P + PSP+ + PPT M + P T P +T PLPP+
Sbjct: 1717 STTTPSPPPTTMTTPSPT-TTPSPPTTTMTTLPPTTTSSPLTTTPLPPS 1764
Score = 75.1 bits (183), Expect = 5e-13
Identities = 104/477 (21%), Positives = 146/477 (30%), Gaps = 91/477 (19%)
Query: 248 PLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTP 307
P+ + ++ P+P + P PP ++ P ++ PP T T P T +P
Sbjct: 1391 PMDKCITTPSP---------PTTTPSPPPTSTTTLPPTTTPSPPTTTTTT-PPPTTTPSP 1440
Query: 308 PATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPA 367
P T ++ P P +P P + P P+ P P+++P+P
Sbjct: 1441 PITTTTT-PPPTTTPSPPIS------------TTTTPPPTTTPSPPTTTPSPPTTTPSP- 1486
Query: 368 PSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFP---APSEPSAPGW 424
P+ PT + P T + T+ P PS P+
Sbjct: 1487 PTTTTTTPPPTTTPSPPT---------------TTPITPPASTTTLPPTTTPSPPTTTTT 1531
Query: 425 WPPPS---SPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPRE 481
PPP+ SP P PP PT P T P + P S P
Sbjct: 1532 TPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTI 1591
Query: 482 AQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSL 541
PP SP + PP P S + P+ P P+ +
Sbjct: 1592 TTTTPPPTT------TPSPPTTTTTTPPPTTTP-SPPTTTPITP----------PTSTTT 1634
Query: 542 LPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPE 601
LPPT P T P +T P PP P PP P
Sbjct: 1635 LPPTTTPSPPPTTTTTPPPTTTPSPPTTT------------------TPSPPITTTTTPP 1676
Query: 602 NQQTCLPAPESPFATR-SPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPTL 660
T P SP T SP + +T S T S TP+ P P
Sbjct: 1677 PTTT----PSSPITTTPSP------PTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPT 1726
Query: 661 SGFLESPLKYLDTPTKSLLDTPAKRAQAEFPTCDCVEQIVEKDEGPYYTHLGSGPTV 717
+ SP PT ++ P + T I P+ T + P V
Sbjct: 1727 TMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCV 1783
Score = 52.8 bits (125), Expect = 3e-06
Identities = 63/270 (23%), Positives = 86/270 (31%), Gaps = 36/270 (13%)
Query: 167 PRLPGPLPPGEAGLPAP-STRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAI 225
P P PP + P ST L + P SP + + + + I
Sbjct: 1534 PPTTTPSPPTTTPITPPTSTTTLPPTTTP--SPPPTTTTTPPPTTTPSPPTTTTPSPPTI 1591
Query: 226 EALTQLSSALPQPSHST----PQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSS 281
T + P P +T P + P P +P P S + L + P PP ++
Sbjct: 1592 TTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT-LPPTTTPSPPPTTTTT 1650
Query: 282 FAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQS 341
P ++ PP T P T PP T SS PSP
Sbjct: 1651 PPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTT--------------M 1696
Query: 342 VFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKR 401
P P+ P PSS+ P+P P P+P++ P T L
Sbjct: 1697 TTPSPTTTPSSPITTTTTPSSTTTPSPPPTTM-TTPSPTTTPSPPTTTMTTLPP------ 1749
Query: 402 SLFLEQVHDTSFPAPSEPSAPGWWPPPSSP 431
TS P + P P PP SP
Sbjct: 1750 -------TTTSSPLTTTPLPPSITPPTFSP 1772
Score = 48.5 bits (114), Expect = 5e-05
Identities = 94/512 (18%), Positives = 155/512 (30%), Gaps = 55/512 (10%)
Query: 175 PGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSA 234
P G P+T P+ ++ +P P + + T TQ +
Sbjct: 2141 PTPTGTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2197
Query: 235 LPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATP 294
P + +T P P P +P + + P + P ++ T
Sbjct: 2198 TPITTTTTVT---PTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTT 2251
Query: 295 RTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPK 354
T P GT TP TP ++ P+P P G+ + + PT
Sbjct: 2252 VTPTPTPTGTQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTP 2304
Query: 355 VKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFP 414
+ P+++P + V PT + P T + T+
Sbjct: 2305 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--------------------TPITTTTTV 2344
Query: 415 APSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPV-GTEKAAPGIKPS-VRKPI 472
P+ P+ G P ++P+ P TP P+ T P P+ + P
Sbjct: 2345 TPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2403
Query: 473 QIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP-APLPASQGSAVP-LPPEPSLA 530
+ P P G ++P + + P P G+ P P +
Sbjct: 2404 TTPITTTTTVTPTPTPT------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2457
Query: 531 LFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLP 590
P+P+ PT + + P TG P + P
Sbjct: 2458 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TP 2511
Query: 591 GPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPT 650
P P T + +P T++P I ++ VT T T T
Sbjct: 2512 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2571
Query: 651 KAENPLTPTLSGFLESPLKYLDTPTKSLLDTP 682
P TPT +G ++P T T ++ TP
Sbjct: 2572 TTVTP-TPTPTG-TQTPTTTPITTTTTVTPTP 2601
Score = 48.5 bits (114), Expect = 5e-05
Identities = 94/512 (18%), Positives = 155/512 (30%), Gaps = 55/512 (10%)
Query: 175 PGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSA 234
P G P+T P+ ++ +P P + + T TQ +
Sbjct: 2463 PTPTGTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2519
Query: 235 LPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATP 294
P + +T P P P +P + + P + P ++ T
Sbjct: 2520 TPITTTTTVT---PTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTT 2573
Query: 295 RTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPK 354
T P GT TP TP ++ P+P P G+ + + PT
Sbjct: 2574 VTPTPTPTGTQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTP 2626
Query: 355 VKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFP 414
+ P+++P + V PT + P T + T+
Sbjct: 2627 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--------------------TPITTTTTV 2666
Query: 415 APSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPV-GTEKAAPGIKPS-VRKPI 472
P+ P+ G P ++P+ P TP P+ T P P+ + P
Sbjct: 2667 TPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2725
Query: 473 QIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP-APLPASQGSAVP-LPPEPSLA 530
+ P P G ++P + + P P G+ P P +
Sbjct: 2726 TTPITTTTTVTPTPTPT------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2779
Query: 531 LFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLP 590
P+P+ PT + + P TG P + P
Sbjct: 2780 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TP 2833
Query: 591 GPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPT 650
P P T + +P T++P I ++ VT T T T
Sbjct: 2834 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2893
Query: 651 KAENPLTPTLSGFLESPLKYLDTPTKSLLDTP 682
P TPT +G ++P T T ++ TP
Sbjct: 2894 TTVTP-TPTPTG-TQTPTTTPITTTTTVTPTP 2923
Score = 48.5 bits (114), Expect = 5e-05
Identities = 94/512 (18%), Positives = 155/512 (30%), Gaps = 55/512 (10%)
Query: 175 PGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSA 234
P G P+T P+ ++ +P P + + T TQ +
Sbjct: 2785 PTPTGTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2841
Query: 235 LPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATP 294
P + +T P P P +P + + P + P ++ T
Sbjct: 2842 TPITTTTTVT---PTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTT 2895
Query: 295 RTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPK 354
T P GT TP TP ++ P+P P G+ + + PT
Sbjct: 2896 VTPTPTPTGTQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTP 2948
Query: 355 VKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFP 414
+ P+++P + V PT + P T + T+
Sbjct: 2949 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--------------------TPITTTTTV 2988
Query: 415 APSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPV-GTEKAAPGIKPS-VRKPI 472
P+ P+ G P ++P+ P TP P+ T P P+ + P
Sbjct: 2989 TPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3047
Query: 473 QIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP-APLPASQGSAVP-LPPEPSLA 530
+ P P G ++P + + P P G+ P P +
Sbjct: 3048 TTPITTTTTVTPTPTPT------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3101
Query: 531 LFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLP 590
P+P+ PT + + P TG P + P
Sbjct: 3102 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TP 3155
Query: 591 GPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPT 650
P P T + +P T++P I ++ VT T T T
Sbjct: 3156 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3215
Query: 651 KAENPLTPTLSGFLESPLKYLDTPTKSLLDTP 682
P TPT +G ++P T T ++ TP
Sbjct: 3216 TTVTP-TPTPTG-TQTPTTTPITTTTTVTPTP 3245
Score = 48.5 bits (114), Expect = 5e-05
Identities = 94/512 (18%), Positives = 155/512 (30%), Gaps = 55/512 (10%)
Query: 175 PGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSA 234
P G P+T P+ ++ +P P + + T TQ +
Sbjct: 3107 PTPTGTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3163
Query: 235 LPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATP 294
P + +T P P P +P + + P + P ++ T
Sbjct: 3164 TPITTTTTVT---PTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTT 3217
Query: 295 RTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPK 354
T P GT TP TP ++ P+P P G+ + + PT
Sbjct: 3218 VTPTPTPTGTQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTP 3270
Query: 355 VKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFP 414
+ P+++P + V PT + P T + T+
Sbjct: 3271 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--------------------TPITTTTTV 3310
Query: 415 APSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPV-GTEKAAPGIKPS-VRKPI 472
P+ P+ G P ++P+ P TP P+ T P P+ + P
Sbjct: 3311 TPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3369
Query: 473 QIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP-APLPASQGSAVP-LPPEPSLA 530
+ P P G ++P + + P P G+ P P +
Sbjct: 3370 TTPITTTTTVTPTPTPT------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3423
Query: 531 LFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLP 590
P+P+ PT + + P TG P + P
Sbjct: 3424 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TP 3477
Query: 591 GPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPT 650
P P T + +P T++P I ++ VT T T T
Sbjct: 3478 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3537
Query: 651 KAENPLTPTLSGFLESPLKYLDTPTKSLLDTP 682
P TPT +G ++P T T ++ TP
Sbjct: 3538 TTVTP-TPTPTG-TQTPTTTPITTTTTVTPTP 3567
Score = 48.5 bits (114), Expect = 5e-05
Identities = 94/512 (18%), Positives = 155/512 (30%), Gaps = 55/512 (10%)
Query: 175 PGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSA 234
P G P+T P+ ++ +P P + + T TQ +
Sbjct: 3429 PTPTGTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3485
Query: 235 LPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATP 294
P + +T P P P +P + + P + P ++ T
Sbjct: 3486 TPITTTTTVT---PTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTT 3539
Query: 295 RTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPK 354
T P GT TP TP ++ P+P P G+ + + PT
Sbjct: 3540 VTPTPTPTGTQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTP 3592
Query: 355 VKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFP 414
+ P+++P + V PT + P T + T+
Sbjct: 3593 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--------------------TPITTTTTV 3632
Query: 415 APSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPV-GTEKAAPGIKPS-VRKPI 472
P+ P+ G P ++P+ P TP P+ T P P+ + P
Sbjct: 3633 TPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3691
Query: 473 QIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP-APLPASQGSAVP-LPPEPSLA 530
+ P P G ++P + + P P G+ P P +
Sbjct: 3692 TTPITTTTTVTPTPTPT------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3745
Query: 531 LFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLP 590
P+P+ PT + + P TG P + P
Sbjct: 3746 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TP 3799
Query: 591 GPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPT 650
P P T + +P T++P I ++ VT T T T
Sbjct: 3800 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3859
Query: 651 KAENPLTPTLSGFLESPLKYLDTPTKSLLDTP 682
P TPT +G ++P T T ++ TP
Sbjct: 3860 TTVTP-TPTPTG-TQTPTTTPITTTTTVTPTP 3889
Score = 48.1 bits (113), Expect = 7e-05
Identities = 94/521 (18%), Positives = 155/521 (29%), Gaps = 54/521 (10%)
Query: 175 PGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSA 234
P G P+T P+ ++ +P P + + T TQ +
Sbjct: 3751 PTPTGTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3807
Query: 235 LPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATP 294
P + +T P P P +P + + P + P ++ T
Sbjct: 3808 TPITTTTTVT---PTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTT 3861
Query: 295 RTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPK 354
T P GT TP TP ++ P+P P G+ + + PT
Sbjct: 3862 VTPTPTPTGTQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTP 3914
Query: 355 VKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFP 414
+ P+++P + V PT + P T + T+
Sbjct: 3915 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--------------------TPITTTTTV 3954
Query: 415 APSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPV-GTEKAAPGIKPS-VRKPI 472
P+ P+ G P ++P+ P TP P+ T P P+ + P
Sbjct: 3955 TPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4013
Query: 473 QIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP-APLPASQGSAVP-LPPEPSLA 530
+ P P G ++P + + P P G+ P P +
Sbjct: 4014 TTPITTTTTVTPTPTPT------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4067
Query: 531 LFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLP 590
P+P+ PT + + P TG P + P
Sbjct: 4068 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TP 4121
Query: 591 GPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPT 650
P P T + +P T++P I ++ VT T T T
Sbjct: 4122 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4181
Query: 651 KAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEFP 691
P TPT +G P + T + L T ++ P
Sbjct: 4182 TTVTP-TPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTP 4221
Score = 46.6 bits (109), Expect = 2e-04
Identities = 78/411 (18%), Positives = 126/411 (30%), Gaps = 46/411 (11%)
Query: 276 PEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSA 335
P + P ++ T T P GT TP TP ++ P+P P G+
Sbjct: 1911 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-------TGTQ 1963
Query: 336 SDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQ 395
+ + PT + P+++P + V PT + P T
Sbjct: 1964 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT---------- 2013
Query: 396 HLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPV 455
+ T+ P+ P+ G P ++P+ P TP P+
Sbjct: 2014 ----------TPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2062
Query: 456 -GTEKAAPGIKPS-VRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP-AP 512
T P P+ + P + P P G ++P + + P
Sbjct: 2063 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT------GTQTPTTTPITTTTTVTP 2116
Query: 513 LPASQGSAVP-LPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDK 571
P G+ P P + P+P+ PT + + P TG P
Sbjct: 2117 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2176
Query: 572 LEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVT 631
+ P P P T + +P T++P I ++ VT
Sbjct: 2177 ITTTTTVTPTP------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2230
Query: 632 VLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTP 682
T T T P TPT +G ++P T T ++ TP
Sbjct: 2231 PTPTPTGTQTPTTTPITTTTTVTP-TPTPTG-TQTPTTTPITTTTTVTPTP 2279
Score = 46.2 bits (108), Expect = 3e-04
Identities = 77/403 (19%), Positives = 124/403 (30%), Gaps = 46/403 (11%)
Query: 284 PDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVF 343
P ++ T T P GT TP TP ++ P+P P G+ + +
Sbjct: 1896 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPIT 1948
Query: 344 KRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSL 403
PT + P+++P + V PT + P T
Sbjct: 1949 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT------------------ 1990
Query: 404 FLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPV-GTEKAAP 462
+ T+ P+ P+ G P ++P+ P TP P+ T P
Sbjct: 1991 --TPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2047
Query: 463 GIKPS-VRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPP-APLPASQGSA 520
P+ + P + P P G ++P + + P P G+
Sbjct: 2048 TPTPTGTQTPTTTPITTTTTVTPTPTPT------GTQTPTTTPITTTTTVTPTPTPTGTQ 2101
Query: 521 VP-LPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQF 579
P P + P+P+ PT + + P TG P +
Sbjct: 2102 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2161
Query: 580 EAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFH 639
P P P T + +P T++P I ++ VT T
Sbjct: 2162 PTP------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2215
Query: 640 SEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTP 682
T T P TPT +G ++P T T ++ TP
Sbjct: 2216 QTPTTTPITTTTTVTP-TPTPTG-TQTPTTTPITTTTTVTPTP 2256
Score = 40.0 bits (92), Expect = 0.019
Identities = 73/352 (20%), Positives = 107/352 (30%), Gaps = 75/352 (21%)
Query: 175 PGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSA 234
P G P+T P+ ++ +P P + + T TQ +
Sbjct: 4073 PTPTGTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4129
Query: 235 LPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATP 294
P + +T P P P +P + + P + P ++ T
Sbjct: 4130 TPITTTTTVT---PTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTT 4183
Query: 295 RTEFPEAWGTDTPPAT----------------PRSSWPMP-RPSPDPMAELEQLLGSASD 337
T P GT T P T P SS P R + P+ E LL +
Sbjct: 4184 VTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPP 4243
Query: 338 YIQSVFKRPEALPTKPKVK------VEAPSSSPAPAPSPVL-----QREAPTPSSEPDTH 386
I+ P + PT P PS++ +P +P APTPS+ T
Sbjct: 4244 AIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTT 4303
Query: 387 QKAQTALQQHLH------------HKRSLFLEQVHDTSFPAPSEPSAPGW---------- 424
A T L + S+ + V + ++ AP E G
Sbjct: 4304 TSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNC 4363
Query: 425 ----------WPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKP 466
W PS+P P K PTP+ K PG KP
Sbjct: 4364 SLSCTLEFYNWSCPSTP------SPTPTPSKSTPTPSKPSSTPSKPTPGTKP 4409
Score = 36.2 bits (82), Expect = 0.27
Identities = 37/154 (24%), Positives = 56/154 (36%), Gaps = 11/154 (7%)
Query: 173 LPPGEAGLPAPSTR---PLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALT 229
LPP P P+T P ++ P + P++ + S T T
Sbjct: 1635 LPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTT 1694
Query: 230 QLSSALPQPSHSTPQASCPLPEAL---SPPAPFRSPQSYLRAPSWPV-----VPPEEHSS 281
+++ P + S+P + P + SPP + S PS P +PP SS
Sbjct: 1695 TMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSS 1754
Query: 282 FAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSW 315
+ P TP T P + T T P P +W
Sbjct: 1755 PLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNW 1788
Score = 35.4 bits (80), Expect = 0.46
Identities = 60/236 (25%), Positives = 84/236 (35%), Gaps = 36/236 (15%)
Query: 170 PGPLPPG-EAGLPA-PSTRPLLSSEVPQISPQEGLP-LSQSALSIAKEKNISLQTAIAIE 226
P P P G + G P ST P+ P+ P S+S S E L T +
Sbjct: 4186 PTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST---LP 4242
Query: 227 ALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDS 286
+++S P + + P + PP+ SP P P SS AP
Sbjct: 4243 PAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSP------PGTPTRGTTTGSSSAP-- 4294
Query: 287 SAFPPATPRTEFPEAW-GTDTPPATP---RSSWPMPRPSPDPMAEL----------EQLL 332
P+T +T AW T TP +TP R++ P PS + + E
Sbjct: 4295 ---TPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYN 4351
Query: 333 GSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQK 388
G+ D F T PS+ P+P+P + PTPS T K
Sbjct: 4352 GTYGD--TCYFVNCSLSCTLEFYNWSCPST---PSPTPTPSKSTPTPSKPSSTPSK 4402
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 75.1 bits (183), Expect = 5e-13
Identities = 132/546 (24%), Positives = 190/546 (34%), Gaps = 78/546 (14%)
Query: 134 PPNCNCDGPECPDYLEWLEGKIKSVVMEGGEERPR-LPGPLPPGEAGLPAPSTRPLLSSE 192
PP GP C E +G+I + G E PR P PLP E L P++R + ++
Sbjct: 481 PPPAWLKGPACRAARE--DGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQ 538
Query: 193 VPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEA 252
P P + S+ S + + S ++ L+ ++ PLP
Sbjct: 539 DSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSID-----------PLPR- 586
Query: 253 LSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAF----PPATPRTEFPEAWGTDT-P 307
PP+P ++PQ P +PP SS ++S PR FP+ P
Sbjct: 587 --PPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGP 644
Query: 308 PATPRSSWPMPRPSPDPMAELEQLLGSASDY----IQSVFKRPEALPTKP---------- 353
P P S P+P P + EL D+ ++ F+ P P
Sbjct: 645 PPGPLSK--APQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKML 702
Query: 354 ---------KVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLF 404
+ + EA + P P ++P P+ T A+ +
Sbjct: 703 DESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTT 762
Query: 405 LEQVHDTSFPAPSEPSAP-GWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPG 463
Q + P P P +PPPS P P P PP P+PA G
Sbjct: 763 ATQEEEKKPPPALPPPPPLAKFPPPSQPQP--PPPPP-------PSPASLLKSLASVLEG 813
Query: 464 IKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPL 523
K R +RP PL P Q P S P + P++QGS P
Sbjct: 814 QKYCYRGTGAAVSTRPG---PL--PTTQYS----PGPPSGATALPPTSAAPSAQGS--PQ 862
Query: 524 PPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPA---DDKLEELIRQFE 580
P S + F+ S + E P PMT QP LPPA + LEE+ R E
Sbjct: 863 PSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACE 922
Query: 581 AEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHS 640
P+ P+ E PA P Q K E +G V +S +C
Sbjct: 923 TLVERVGRSATDPADPVDTAE------PADSGTERLLPPAQAK-EEAGGVAAVSGSCKRR 975
Query: 641 EEGGQE 646
++ Q+
Sbjct: 976 QKEHQK 981
Score = 55.8 bits (133), Expect = 3e-07
Identities = 131/576 (22%), Positives = 190/576 (32%), Gaps = 105/576 (18%)
Query: 167 PRLPGPLPPG-EAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAI 225
P PGP PPG E+ P+TRP P L S+ S T +
Sbjct: 334 PPGPGPRPPGAESHGCLPATRP----------PGSDLRESRVQRSRMDSSVSPAATTACV 383
Query: 226 EALTQLSSALPQPSHSTPQASCPLPEALS-PPAPFRSPQSYLRAPSWPV-----VPPEEH 279
LP + S+ +S P P + + P+ V + P H
Sbjct: 384 PYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAH 443
Query: 280 SSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPS----PDPMAELEQLLGSA 335
SS P A P ATP P + PP PR P P P+ P A E
Sbjct: 444 SSRKPFLGA-PAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAARED----- 497
Query: 336 SDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQRE---APTPSSEPDTHQKAQTA 392
+ ++ +F E P PAP P+ RE P S Q + T
Sbjct: 498 GEILEELFFGTE--------------GPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTP 543
Query: 393 LQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPS------SPVPRLPD--RPPKEKK 444
S + S S P+ P +PPP P+PR P + P++
Sbjct: 544 PTPPTPTTSS-----SNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPP 598
Query: 445 KKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQE 504
T A P S R+P + RPR + P P V G S A
Sbjct: 599 LVPLTLALPPAPPSSCHQNTSGSFRRP---ESPRPRVSFPKTPEVGPGPPPGPLSKA--- 652
Query: 505 VQAHPPAPLPASQGSAVPLPPE-PSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTG 563
P P+P G LP P L F P+P D + P+ L G
Sbjct: 653 -----PQPVPPGVGE---LPARGPRLFDFPPTPLED-------QFEEPAEFKILPDGLAN 697
Query: 564 PLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIK 623
+ D+ + + Q + E G + P P+++P + +SPF T +
Sbjct: 698 IMKMLDESIRKEEEQQQHEAGVA------PQPPLKEP------FASLQSPFPTDTAPTTT 745
Query: 624 IESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPA 683
+ T +TT + +E P A P PL P++ P
Sbjct: 746 APAVAVTTTTTTTTTTTATQEEEKKPPPALPP---------PPPLAKFPPPSQPQPPPPP 796
Query: 684 KRAQAEFPTCDCVEQIVEKDEGPYYTHLGSGPTVAS 719
+ A ++ + EG Y + G+G V++
Sbjct: 797 PPSPASL-----LKSLASVLEGQKYCYRGTGAAVST 827
Score = 45.4 bits (106), Expect = 4e-04
Identities = 108/493 (21%), Positives = 154/493 (31%), Gaps = 104/493 (21%)
Query: 168 RLPGPLPPGEAGLPAPSTR----PLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAI 223
+ P P+PPG LPA R P E P E L +I K + S++
Sbjct: 651 KAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEE 710
Query: 224 AIEALTQLSSALPQPSHSTPQASC--PLPEALSPP--APFRSPQSYLRAPSWPVVPPEEH 279
E + PQP P AS P P +P AP + + + EE
Sbjct: 711 --EQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEE 768
Query: 280 SSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYI 339
P A PP P +FP PP+ P+ P P P P P + L+ L
Sbjct: 769 KKPPP---ALPPPPPLAKFP-------PPSQPQ---PPPPPPPSPASLLKSLASVLEGQK 815
Query: 340 QSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHH 399
A+ T+P S P+ + L + PS++ A ++ Q
Sbjct: 816 YCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSG 875
Query: 400 KRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKL-----------P 448
+ + P P P+ P PPP S P + E+ +
Sbjct: 876 GPWARERRAGEEPVPGPMTPTQP---PPPLSLPPARSESEVLEEISRACETLVERVGRSA 932
Query: 449 TPAGGPVGTEKAAPGIKPSVRKPIQIKKS------------------------------- 477
T PV T + A + P Q K+
Sbjct: 933 TDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKD 992
Query: 478 ----RPRE----AQPLFPPVRQIVLEGLRSPASQEVQAHP-----------------PAP 512
RPRE A+ P + + G S+E+Q PAP
Sbjct: 993 SVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAP 1052
Query: 513 LPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKL 572
A SA P PP S+ ++ PP + +L G PP + K
Sbjct: 1053 PSAPAPSAQPTPPSASVP--GKKAREEAPGPPGVSRADMLKLRSLSEG-----PPKELK- 1104
Query: 573 EELIRQFEAEFGD 585
IR + E GD
Sbjct: 1105 ---IRLIKVESGD 1114
Score = 39.3 bits (90), Expect = 0.032
Identities = 83/344 (24%), Positives = 113/344 (32%), Gaps = 40/344 (11%)
Query: 367 APSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVH---DTSFPAPSEPSAPG 423
A PV+Q P S P + L +R EQ P P P P
Sbjct: 201 AEPPVVQPVPPAALSGPS----GEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPP 256
Query: 424 WWPPPSSPVPRLPDRPPKEKKKK--LPTPAGGPVGTEK--AAPGIKPSVRKPIQIKKSRP 479
PPP P+P L PP + K T G G E+ +AP + R + P
Sbjct: 257 PPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYP 316
Query: 480 REAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQ--GSAV------------PLPP 525
A PP ++V P + A LPA++ GS + + P
Sbjct: 317 APAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSP 376
Query: 526 EPSLALFAPSPSRDSLLP--PTQEMRSPSPMTALQPGSTGP-LPPADD-KLEELIRQFEA 581
+ A +PSR LP T S S T L+ P +P AD + L
Sbjct: 377 AATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHG 436
Query: 582 EFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSE 641
G S P + + P P SP P+ ++ A + C +
Sbjct: 437 RLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPA-WLKGPACRAAR 495
Query: 642 EGGQ---------EATPTKAENPLTPTLSGFLESPLKYLDTPTK 676
E G+ E P A PL P GFL P T+
Sbjct: 496 EDGEILEELFFGTEGPPRPAPPPL-PHREGFLGPPASRFSVGTQ 538
Score = 37.7 bits (86), Expect = 0.093
Identities = 42/120 (35%), Positives = 53/120 (44%), Gaps = 17/120 (14%)
Query: 484 PLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSP-----SR 538
P PP R L G R AS Q PAPLP S GS+ P +P A AP+P
Sbjct: 32 PPHPPPRSAWLPGGRCSASIG-QPPLPAPLPPSHGSSSGHPSKPYYAPGAPTPRPLHGKL 90
Query: 539 DSLLPPTQE-MRSPSPMTALQPG---STGPLPPADDKLEELIRQFEA--EFGDSFGLPGP 592
+SL Q +R P+ QPG G L ++ EE R + + +G SF GP
Sbjct: 91 ESLHGCVQALLREPA-----QPGLWEQLGQLYESEHDSEEATRCYHSALRYGGSFAELGP 145
Score = 37.4 bits (85), Expect = 0.12
Identities = 102/462 (22%), Positives = 147/462 (31%), Gaps = 108/462 (23%)
Query: 267 RAPSWPVVPPEEHSSFAPDSS--AFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDP 324
RA PVV P ++ + S P R + T PP P P+P P P P
Sbjct: 199 RAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPP 258
Query: 325 MAELEQLLGSASDYIQSVFK------------RPEALPTKPKVKVEAPSSSPAPAPSPVL 372
L G A+ + K PE + P + E S P P P P
Sbjct: 259 PPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYP-- 316
Query: 373 QREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSA------PGWWP 426
AP ++ P H+ A P P P A P P
Sbjct: 317 ---APAYTAHPPGHRLVPAA------------------PPGPGPRPPGAESHGCLPATRP 355
Query: 427 PPS----------------SP------VPRLPDRPPKEKKKKLP---TPAGGPVGTEKAA 461
P S SP VP P RPP LP T + +
Sbjct: 356 PGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPP-----GLPGTTTSSSSSSSSNTGL 410
Query: 462 PGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAV 521
G++P+ P A P ++ G P++ P PA+ +
Sbjct: 411 RGVEPNPGIP---------GADHYQTPALEVSHHGRLGPSAHS-SRKPFLGAPAAT-PHL 459
Query: 522 PLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEA 581
LPP PS P P PP ++ P+ A + G + LEEL
Sbjct: 460 SLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDG---------EILEELF----- 505
Query: 582 EFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSE 641
FG GPP +++ L P S F+ + + +T+ +S
Sbjct: 506 -----FGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS---HTPPTPPTPTTSSSNSN 557
Query: 642 EGGQEATPT-KAENPLTPTLSGFLESPLKYLDTPTKSLLDTP 682
G ++P P P L+ ++ PL +P ++ D P
Sbjct: 558 SGSHSSSPAGPVSFPPPPYLARSID-PLPRPPSPAQNPQDPP 598
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 74.7 bits (182), Expect = 7e-13
Identities = 91/349 (26%), Positives = 125/349 (35%), Gaps = 63/349 (18%)
Query: 272 PVVPPEEHSSFAPDSSAFPPATP-RTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ 330
P++PP S+ A S PP+ P R P PP R+ P PRP
Sbjct: 127 PLLPPGGRSTSAKPFS--PPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPD--------- 175
Query: 331 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ 390
+GS D I P +P+ P+ +P + +P ++ +P P+ P +
Sbjct: 176 -VGSKPDSI------PPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRG- 227
Query: 391 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP 450
TAL + L +S P + P P P +P L D+PP P P
Sbjct: 228 TALGGGSIRQSPL------SSSSPFSNRP------PLPPTPSRALDDKPPPP-----PPP 270
Query: 451 AGG-PVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHP 509
G P +A P P KP RP + PP P P
Sbjct: 271 VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP-----------PPPPSRPGPP 319
Query: 510 PAPLPASQGSAVPLPPEPSLALFA-----PSPSRDSLLPPTQEMRSPSPMTALQPGSTGP 564
P P +S P P+ +L+L + PSP R LPP R P P+ PG +GP
Sbjct: 320 PLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRD-PPGRSGP 378
Query: 565 LPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESP 613
LPP S LP P +P + + P P P
Sbjct: 379 LPPPP--------PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLP 419
Score = 64.3 bits (155), Expect = 9e-10
Identities = 90/350 (25%), Positives = 112/350 (32%), Gaps = 83/350 (23%)
Query: 235 LPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFP-PAT 293
+P P H + PP P R+ R P PP PDS P P+T
Sbjct: 152 VPSPGHRS-----------GPPEPQRN-----RMP-----PPRPDVGSKPDSIPPPVPST 190
Query: 294 PRT--EFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLG-----SASDYIQSVFKRP 346
PR P G+ P PR P P P P P L G S RP
Sbjct: 191 PRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRP 250
Query: 347 EALPTKPKVKVEAPSSSPAPAPS-PVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFL 405
PT + + P P P + P + REA P P + K S
Sbjct: 251 PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPP--PPQNNKPPVP---------STPR 299
Query: 406 EQVHDTSFPAPSEPSAPGWWPPPSSP-------VPRLPDRPPKEKKKKLPTPAGGPVGTE 458
+ P P PS PG PPP P PRLP R P P+ G G
Sbjct: 300 PSASSQAPPPPPPPSRPG--PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG-- 355
Query: 459 KAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQG 518
PL PP + +R P + PP P+ +
Sbjct: 356 -------------------------PLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGS 390
Query: 519 SAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPA 568
++ LP P L PSR + P R P P G+ P PP+
Sbjct: 391 TSRALPATPQL------PSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434
Score = 51.2 bits (121), Expect = 8e-06
Identities = 103/405 (25%), Positives = 131/405 (32%), Gaps = 118/405 (29%)
Query: 165 ERPRLPGPLP-----PGEAGLPAPST-RPLLSSEVPQISPQ-EGLPLSQSALSIAKEKNI 217
+R R+P P P P P PST RP+ SS + SP G P S
Sbjct: 165 QRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPG 224
Query: 218 SLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPE 277
+ TA+ ++ Q + P + P PLP P P R+ P PP
Sbjct: 225 NRGTALGGGSIRQSPLSSSSPFSNRP----PLP-----PTPSRALDDKPPPP-----PPP 270
Query: 278 EHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASD 337
+ + A PP P+ P P+TPR S P P P
Sbjct: 271 VGNRPSIHREAVPPPPPQNNKPPV------PSTPRPSASSQAPPPPP------------- 311
Query: 338 YIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHL 397
P S P P P P P+ S +T + Q
Sbjct: 312 ----------------------PPSRPGPPPLP------PSSSGNDETPRLPQ------- 336
Query: 398 HHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGT 457
R+L L +S P P G PPP S P P R P + LP P PV
Sbjct: 337 ---RNLSL----SSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPP--PVSR 387
Query: 458 EKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQ 517
+ SR A P P G+ SP S P PLP +
Sbjct: 388 NGST---------------SRALPATPQLPS-----RSGVDSPRS-----GPRPPLPPDR 422
Query: 518 GSA-VPLPPEPSLAL---FAPSPSRDS-----LLPPTQEMRSPSP 553
SA P PP PS ++ F SP D P ++ P P
Sbjct: 423 PSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEP 467
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 74.7 bits (182), Expect = 7e-13
Identities = 91/349 (26%), Positives = 125/349 (35%), Gaps = 63/349 (18%)
Query: 272 PVVPPEEHSSFAPDSSAFPPATP-RTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ 330
P++PP S+ A S PP+ P R P PP R+ P PRP
Sbjct: 127 PLLPPGGRSTSAKPFS--PPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPD--------- 175
Query: 331 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ 390
+GS D I P +P+ P+ +P + +P ++ +P P+ P +
Sbjct: 176 -VGSKPDSI------PPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRG- 227
Query: 391 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTP 450
TAL + L +S P + P P P +P L D+PP P P
Sbjct: 228 TALGGGSIRQSPL------SSSSPFSNRP------PLPPTPSRALDDKPPPP-----PPP 270
Query: 451 AGG-PVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHP 509
G P +A P P KP RP + PP P P
Sbjct: 271 VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP-----------PPPPSRPGPP 319
Query: 510 PAPLPASQGSAVPLPPEPSLALFA-----PSPSRDSLLPPTQEMRSPSPMTALQPGSTGP 564
P P +S P P+ +L+L + PSP R LPP R P P+ PG +GP
Sbjct: 320 PLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRD-PPGRSGP 378
Query: 565 LPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESP 613
LPP S LP P +P + + P P P
Sbjct: 379 LPPPP--------PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLP 419
Score = 64.3 bits (155), Expect = 9e-10
Identities = 90/350 (25%), Positives = 112/350 (32%), Gaps = 83/350 (23%)
Query: 235 LPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFP-PAT 293
+P P H + PP P R+ R P PP PDS P P+T
Sbjct: 152 VPSPGHRS-----------GPPEPQRN-----RMP-----PPRPDVGSKPDSIPPPVPST 190
Query: 294 PRT--EFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLG-----SASDYIQSVFKRP 346
PR P G+ P PR P P P P P L G S RP
Sbjct: 191 PRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRP 250
Query: 347 EALPTKPKVKVEAPSSSPAPAPS-PVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFL 405
PT + + P P P + P + REA P P + K S
Sbjct: 251 PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPP--PPQNNKPPVP---------STPR 299
Query: 406 EQVHDTSFPAPSEPSAPGWWPPPSSP-------VPRLPDRPPKEKKKKLPTPAGGPVGTE 458
+ P P PS PG PPP P PRLP R P P+ G G
Sbjct: 300 PSASSQAPPPPPPPSRPG--PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG-- 355
Query: 459 KAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQG 518
PL PP + +R P + PP P+ +
Sbjct: 356 -------------------------PLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGS 390
Query: 519 SAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPA 568
++ LP P L PSR + P R P P G+ P PP+
Sbjct: 391 TSRALPATPQL------PSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434
Score = 51.2 bits (121), Expect = 8e-06
Identities = 103/405 (25%), Positives = 131/405 (32%), Gaps = 118/405 (29%)
Query: 165 ERPRLPGPLP-----PGEAGLPAPST-RPLLSSEVPQISPQ-EGLPLSQSALSIAKEKNI 217
+R R+P P P P P PST RP+ SS + SP G P S
Sbjct: 165 QRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPG 224
Query: 218 SLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPE 277
+ TA+ ++ Q + P + P PLP P P R+ P PP
Sbjct: 225 NRGTALGGGSIRQSPLSSSSPFSNRP----PLP-----PTPSRALDDKPPPP-----PPP 270
Query: 278 EHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASD 337
+ + A PP P+ P P+TPR S P P P
Sbjct: 271 VGNRPSIHREAVPPPPPQNNKPPV------PSTPRPSASSQAPPPPP------------- 311
Query: 338 YIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHL 397
P S P P P P P+ S +T + Q
Sbjct: 312 ----------------------PPSRPGPPPLP------PSSSGNDETPRLPQ------- 336
Query: 398 HHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGT 457
R+L L +S P P G PPP S P P R P + LP P PV
Sbjct: 337 ---RNLSL----SSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPP--PVSR 387
Query: 458 EKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQ 517
+ SR A P P G+ SP S P PLP +
Sbjct: 388 NGST---------------SRALPATPQLPS-----RSGVDSPRS-----GPRPPLPPDR 422
Query: 518 GSA-VPLPPEPSLAL---FAPSPSRDS-----LLPPTQEMRSPSP 553
SA P PP PS ++ F SP D P ++ P P
Sbjct: 423 PSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEP 467
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 73.6 bits (179), Expect = 2e-12
Identities = 129/537 (24%), Positives = 186/537 (34%), Gaps = 100/537 (18%)
Query: 178 AGLPAPSTRPLLSSEVPQISPQE---GLPLSQSALSIAKEKNISLQTAIAIEALTQLSSA 234
A P P+ +L S P +P LPL+ + + N + + +A +
Sbjct: 1264 APTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTP 1323
Query: 235 LPQPSHSTPQASCPLPEALSPP---APFRSPQSYLRAPSWPVVPPE--------EHSSFA 283
+P + + S LP L+P P R P L P+ P HS
Sbjct: 1324 VPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSP 1383
Query: 284 PDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVF 343
S++ P A P T +P P SS P P SP P+ L S +
Sbjct: 1384 EVSASAPGAAPLT-------ISSPLHVP-SSLPGPASSPMPIPNSSPLASPVSSTV---- 1431
Query: 344 KRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSL 403
++P + + P++ PAPA +P+ P S P T + AL +
Sbjct: 1432 ----SVPLSSSLPISVPTTLPAPASAPLT-----IPISAPLTVSASGPALLTSV------ 1476
Query: 404 FLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRP---------PKEKKKKLPTPAGGP 454
T AP P+APG PP +P P P + P
Sbjct: 1477 -------TPPLAPVVPAAPG--PPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLL 1527
Query: 455 VGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLP 514
T PG+ +V P+ P + +P QA AP
Sbjct: 1528 APTSSHVPGLNSTVAPA----------CSPVLVPASALASPFPSAPNPAPAQASLLAPAS 1577
Query: 515 -ASQGSAVPLPP--EPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDK 571
ASQ A PL P P A+ APSP+ PP +P P+ A PG+ L +
Sbjct: 1578 SASQALATPLAPMAAPQTAILAPSPA-----PPL----APLPVLAPSPGAAPVLASSQTP 1628
Query: 572 LEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAP-ESPFATRSPKQIKIESSGAV 630
+ + + P P P+ P + QT LPAP SP P ++
Sbjct: 1629 VPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPL----PSPASTQTLALA 1684
Query: 631 TVLSTTCFHSEEGGQEATPTKA---ENPLTPTLSGFLESPLKYLDTPTKSLLDTPAK 684
L+ T GG + T + NP P + L TP SL+ TPA+
Sbjct: 1685 PALAPTL-----GGSSPSQTLSLGTGNPQGPFPTQTLSL------TPASSLVPTPAQ 1730
Score = 72.0 bits (175), Expect = 4e-12
Identities = 110/428 (25%), Positives = 154/428 (35%), Gaps = 66/428 (15%)
Query: 169 LPGPLP-PGEAGLPAPSTRPL-----------LSSEVPQISPQEGLPLSQSA-LSIAKEK 215
+P LP P + +P P++ PL LSS +P IS LP SA L+I
Sbjct: 1403 VPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLP-ISVPTTLPAPASAPLTIP--- 1458
Query: 216 NISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSP----PAPFRSPQSYLRAPSW 271
IS ++ L+S P + P A P P +L+P P+ APS
Sbjct: 1459 -ISAPLTVSASGPALLTSVTPPLAPVVPAA--PGPPSLAPSGASPSASALTLGLATAPSL 1515
Query: 272 PVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPS-PDPMAELEQ 330
H +S+ P T P +P P S+ P PS P+P
Sbjct: 1516 SSSQTPGHPLLLAPTSSHVPGLNSTVAPAC----SPVLVPASALASPFPSAPNPAPAQAS 1571
Query: 331 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQ 390
LL AS Q++ P A P+ + APS +P AP PVL AP+P + P
Sbjct: 1572 LLAPASSASQAL-ATPLAPMAAPQTAILAPSPAPPLAPLPVL---APSPGAAPVLASS-- 1625
Query: 391 TALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPR-LPDRPPKEKKKKLPT 449
T P + S PG +SPVP P P + LP
Sbjct: 1626 -------------------QTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPA 1666
Query: 450 PAGGPVGTEKA------APGIKPSV--RKPIQIKKSRPREAQPLFPP--VRQIVLEGLRS 499
P P+ + + AP + P++ P Q Q FP + L
Sbjct: 1667 PVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVP 1726
Query: 500 PASQEVQAHPPAPL-PASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQ 558
+Q + P PL P S P PP + P+P+ L P S ++Q
Sbjct: 1727 TPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQ 1786
Query: 559 PGSTGPLP 566
+ P P
Sbjct: 1787 TLTLSPAP 1794
Score = 61.2 bits (147), Expect = 8e-09
Identities = 132/490 (26%), Positives = 179/490 (36%), Gaps = 70/490 (14%)
Query: 167 PRLPGP--LPPGEAGLPAPSTRPLLSSEVPQISPQE--GLPLSQSALSIAKEKNISLQTA 222
P PGP L P A P+ S L + P +S + G PL + S + ++ A
Sbjct: 1485 PAAPGPPSLAPSGAS-PSASALTLGLATAPSLSSSQTPGHPLLLAPTS-SHVPGLNSTVA 1542
Query: 223 IAIEALTQLSSALPQPSHSTP-----QASCPLP-----EALSPP-APFRSPQSYLRAPSW 271
A + +SAL P S P QAS P +AL+ P AP +PQ+ + APS
Sbjct: 1543 PACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPS- 1601
Query: 272 PVVPPEEHSSFAPDSSAFPP-ATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQ 330
P P AP A P A+ +T P + TP + S+ P+P P+P
Sbjct: 1602 PAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTP-------- 1653
Query: 331 LLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPT-PSSEPDTHQKA 389
+L +S P LP+ P+S+ A +P L APT S P
Sbjct: 1654 VLAPSSTQTMLPAPVPSPLPS--------PASTQTLALAPAL---APTLGGSSPSQTLSL 1702
Query: 390 QTALQQHLHHKRSLFLEQVHD-TSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLP 448
T Q ++L L PA + APG PP P L P P
Sbjct: 1703 GTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPG---PPLGPTQTLSLAPAPPLAPASP 1759
Query: 449 TPAGGPVGTEKAAPGIKP-SVRKP--IQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEV 505
P T AP S+ P +Q P L P Q + +PAS +
Sbjct: 1760 V-GPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLA---LAPASTQS 1815
Query: 506 QAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTAL---QPGST 562
A + L S A PLP L D+L + PS T+ +P
Sbjct: 1816 PASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQ 1875
Query: 563 GPLPPAD----DKLEELIRQFEAE-------FGDSFGLPGPPSVPIQDPENQQTC-LPAP 610
P PP D LEE ++ +E ++ G P+ E C LP P
Sbjct: 1876 PPPPPRSPFYLDSLEEKRKRQRSERLERIFQLSEAHG----ALAPVYGTEVLDFCTLPQP 1931
Query: 611 -ESPFATRSP 619
SP RSP
Sbjct: 1932 VASPIGPRSP 1941
Score = 58.2 bits (139), Expect = 7e-08
Identities = 151/669 (22%), Positives = 221/669 (33%), Gaps = 127/669 (18%)
Query: 35 TGGPWRVDQKPDWEA---APGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFNR 91
TG V DW A R+ D+ + ++E L +
Sbjct: 2128 TGADTVVFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLISERTVEENILKKANQKRMLG 2187
Query: 92 EMSREAGNNSRG-------------PRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCN 138
+M+ E GN + P P S S + +T + H ++ C
Sbjct: 2188 DMAIEGGNFTTAYFKQQTIRELFDMPLEEPSSSSVPSAPEEEEETVASKQTHILEQALCR 2247
Query: 139 CDGPECPDYLEWLEGKIKSVVMEGGEERPRLPGPLPPGE-AGLPAPSTRPLLSSE----- 192
+ E D + K + V E E P GE AG P + +E
Sbjct: 2248 AEDEE--DIRAATQAKAEQVA-ELAEFNENDGFPAGEGEEAGRPGAEDEEMSRAEQEIAA 2304
Query: 193 -VPQISPQEG-----LPLSQSALSIAKEKNISLQTAIAIEALTQLSSA---LPQPSHSTP 243
V Q++P E L S +S + K Q A + L Q LPQ P
Sbjct: 2305 LVEQLTPIERYAMKFLEASLEEVSREELKQAEEQVEAARKDLDQAKEEVFRLPQEEEEGP 2364
Query: 244 QASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWG 303
A RS ++ +AP P E A + TP +
Sbjct: 2365 GAGDESSCGTGGGTHRRSKKA--KAPERPGTRVSERLRGARAETQGANHTPVISAHQTRS 2422
Query: 304 TDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSS 363
T TPP + +PRP+P RP P AP++
Sbjct: 2423 TTTPPRCSPARERVPRPAP----------------------RPRPTP------ASAPAAI 2454
Query: 364 PAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEP---- 419
PA P PV AP P S P+ T L H+ P+P P
Sbjct: 2455 PALVPVPV---SAPVPISAPN----PITILPVHI---------------LPSPPPPSQIP 2492
Query: 420 --SAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKS 477
S+P PPP+ P P P + L TP+ + + P P+ ++
Sbjct: 2493 PCSSPACTPPPACTPP--PAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPE 2550
Query: 478 RPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAP--------LPASQGSAVPLPPEPSL 529
AQ L P + L + S + + PP LP S+ + P PSL
Sbjct: 2551 AELCAQALASP-ESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSL 2609
Query: 530 ALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGL 589
L A S +P QE +P G+T + P ++L + +S GL
Sbjct: 2610 TLEAGS------IPNGQEQEAPDS----AEGTTLTVLPEGEELPLCV-------SESNGL 2652
Query: 590 PGPPSV----PIQDP-ENQQTCLPAPESPFATRSPK--QIKIESSGAVTVLSTTCFHSEE 642
PPS P+Q+P E +T E+ T SP+ Q + + A S++ S E
Sbjct: 2653 ELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPE 2712
Query: 643 GGQEATPTK 651
G A P +
Sbjct: 2713 GPSPARPPR 2721
Score = 56.2 bits (134), Expect = 3e-07
Identities = 129/561 (22%), Positives = 193/561 (34%), Gaps = 90/561 (16%)
Query: 170 PGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSA----LSIAKEKNISLQTAIAI 225
P P A P P+ L++ P + +P+S S L + E + Q +
Sbjct: 2502 PPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASP 2561
Query: 226 EALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVP---------P 276
E+L S A S T S P+ L P A P S P P P
Sbjct: 2562 ESLELASVA----SSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIP 2617
Query: 277 EEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSW---PMPRPSPDPMAELEQLLG 333
APDS+ T T PE G + P S+ P S +P+ E +
Sbjct: 2618 NGQEQEAPDSAE---GTTLTVLPE--GEELPLCVSESNGLELPPSAASDEPLQEPLEADR 2672
Query: 334 SASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTAL 393
++ + ++ K P + P KP+ V A ++P+ + S E P+P+ P A
Sbjct: 2673 TSEELTEA--KTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADV-- 2728
Query: 394 QQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDR-----PPKEKKKKLP 448
++ P +P P + +LP R KE ++
Sbjct: 2729 -------------EIRGQGTGRPGQPPGP-------KVLRKLPGRLVTVVEEKELVRRRR 2768
Query: 449 TPAGGP------VGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPAS 502
G V A+PG PSVR S P + P+ P L +P
Sbjct: 2769 QQRGAASTLVPGVSETSASPG-SPSVR-----SMSGPESSPPIGGPCEAAPSSSLPTPPQ 2822
Query: 503 QEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSP---------SP 553
Q A L + G + LA+ P+ R PP ++ RSP +P
Sbjct: 2823 QPFIARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPP-KKNRSPADAGRGVDEAP 2881
Query: 554 MTALQPGSTGPLP-PADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPES 612
+ L+ + G P P + L E + +PGP + Q L E
Sbjct: 2882 SSTLKGKTNGADPVPGPETLIVADPVLEPQL-----IPGPQPLGPQPVHRPNPLLSPVEK 2936
Query: 613 PFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYL- 671
R PK + G T+ S +SE Q P +PLTP L L P +
Sbjct: 2937 RRRGRPPKARDLPIPG--TISSAGDGNSESRTQ---PPPHPSPLTP-LPPLLVCPTATVA 2990
Query: 672 -DTPTKSLLDTPAKRAQAEFP 691
T ++ +P KR + P
Sbjct: 2991 NTVTTVTISTSPPKRKRGRPP 3011
Score = 50.4 bits (119), Expect = 1e-05
Identities = 108/479 (22%), Positives = 151/479 (31%), Gaps = 81/479 (16%)
Query: 238 PSHSTPQASCPLPEALSPPAPFRSPQ---SYLRAPSWPVVPPEEHSSFAPDSSAFPPATP 294
P P P PE + P P PQ + L + P PP +S P PP P
Sbjct: 1018 PLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQP 1077
Query: 295 RT-EFPEAW--------GTDTPPATPRSSWPMP----RPSPDPMAELEQLLGSASDYIQS 341
+ P+ GT PP S P P R SP P LL + +
Sbjct: 1078 NSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLT--VPP 1135
Query: 342 VFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQR-------EAPTPSSEPDTHQKAQTALQ 394
+ P A T +++ PAP+P QR +A PS E + + + Q
Sbjct: 1136 GYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQ 1195
Query: 395 --------------QHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPP 440
Q +K +L QV + P + L +P
Sbjct: 1196 RPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPA 1255
Query: 441 KEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPP------VRQIVL 494
+ P GP P PS P S P A + P V +IV+
Sbjct: 1256 HVALIQAVAPTPGPTPV-SVLPSSTPST-TPAPTGLSLPLAANQVPPTMVNNTGVVKIVV 1313
Query: 495 EGLRSPASQEVQAHPPAPLPASQGSAVPLPPEPSL-----------ALFAPSPSRDSLLP 543
V PAP P S G L P P+L AP P+ + P
Sbjct: 1314 RQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRP 1373
Query: 544 PTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQ 603
+ + SPSP + PL + LPGP S P+ P +
Sbjct: 1374 LLKLVHSPSPEVSASAPGAAPL------------TISSPLHVPSSLPGPASSPMPIPNS- 1420
Query: 604 QTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPTLSG 662
SP A+ + + S ++ + T + P A PLT + SG
Sbjct: 1421 --------SPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISA--PLTVSASG 1469
Score = 36.2 bits (82), Expect = 0.27
Identities = 46/210 (21%), Positives = 76/210 (36%), Gaps = 21/210 (10%)
Query: 466 PSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPP 525
P KP+++K +R + P +V+ R+P PP P ++Q + P+P
Sbjct: 984 PPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQ 1043
Query: 526 E-PSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFG 584
P+ + + SP+ L+P + R P P+ LPP L + + G
Sbjct: 1044 VLPASLMVSASPAGPPLIPAS---RPPGPVL---------LPPLQPNSGSLPQVLPSPLG 1091
Query: 585 DSFGLPGPPSVPIQ---DPENQQTCLPAPESPFAT-----RSPKQIKIESSGAVTVLSTT 636
G PP+ + P PAP ++ P + A T +TT
Sbjct: 1092 VLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTT 1151
Query: 637 CFHSEEGGQEATPTKAENPLTPTLSGFLES 666
+ TP L+P + L S
Sbjct: 1152 ATATTTAVPAPTPAPQRLILSPDMQARLPS 1181
Score = 34.3 bits (77), Expect = 1.0
Identities = 84/393 (21%), Positives = 125/393 (31%), Gaps = 88/393 (22%)
Query: 160 MEGGEERPRLPGPLPPG-EAGLPAPSTRP-----------------------LLSSEVPQ 195
M G E P + GP + LP P +P LL+ P
Sbjct: 2796 MSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALLAITPPA 2855
Query: 196 ISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSP 255
+ + G P ++ + + + ++ T + +P P P+ +
Sbjct: 2856 VKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPG 2915
Query: 256 PAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRS-S 314
P P PQ R P++ P E PP P GT + S S
Sbjct: 2916 PQPL-GPQPVHRPN--PLLSPVEKRR-----RGRPPKARDLPIP---GTISSAGDGNSES 2964
Query: 315 WPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVK-VEAPSSSPAPAPS--PV 371
P P P P+ L LL + + + + PK K P + P+P PS PV
Sbjct: 2965 RTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGRPPKNPPSPRPSQLPV 3024
Query: 372 LQR---------------------EAPTPSSEPDTHQKAQTALQQHLHHK--------RS 402
L R E+ SS+ D + + L + S
Sbjct: 3025 LDRDSTSVLESCGLGRRRQPQGQGESEGSSSDEDGSRPLTRLARLRLEAEGMRGRKSGGS 3084
Query: 403 LFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDR--------PPKEKKKKLPTPAGGP 454
+ + + D A S P PP S P+L PP E +K AG P
Sbjct: 3085 MVVAVIQDDLDLADSGPGGLELTPPVVSLTPKLRSTRLRPGSLVPPLETEKLPRKRAGAP 3144
Query: 455 VGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFP 487
VG +PG+ K+ R + PL P
Sbjct: 3145 VG---GSPGL---------AKRGRLQPPSPLGP 3165
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 73.2 bits (178), Expect = 2e-12
Identities = 126/478 (26%), Positives = 161/478 (33%), Gaps = 86/478 (17%)
Query: 235 LPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATP 294
LP PS S P CP P P P SP PP + PP TP
Sbjct: 417 LPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTP 476
Query: 295 ----RTEFPEAWGTDTPPATPRSSWPM---PRPSPDPMAELEQLLGSASDYI-------- 339
E A T P TP S P SP + L + +I
Sbjct: 477 SQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARS 536
Query: 340 QSVFKRP-----EALPTKPKVKVE-----------APSSSPAPAPSPVLQREAPTPSSEP 383
V K P E P PKV+V PAP PSP APTP S P
Sbjct: 537 SRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSP---PRAPTPPSTP 593
Query: 384 -DTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPP----SSPVP---RL 435
+K ++ L++ SL E PAP P AP PPP SS P R
Sbjct: 594 VPLPEKRRSILREPTFRWTSLTRELPPPP--PAPPPPPAPS--PPPAPATSSRRPLLLRA 649
Query: 436 PDRPPKEKKKKL------PTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPRE-AQPLFPP 488
P P E K+ P P G P E P S +P R + P F P
Sbjct: 650 PQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAP 709
Query: 489 VRQIVLEGLRSPASQEVQAH-PPAPLPASQGSAVPLPP----EPSLALFAPSPSRDSLLP 543
V + +P EV H PA Q A L P + L A P + L P
Sbjct: 710 V-------VTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQP 762
Query: 544 PTQEMRSPSPMTALQPGSTG--PLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPE 601
P + P P+ + G PL ++K+ L+++ + + I +
Sbjct: 763 PPSPQQMP-PLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQL-----------FKIDQQQ 810
Query: 602 NQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTT-CFHSEEGGQEATPTKAENPLTP 658
Q+ P SP E +GAV +S SE+ EA + P +P
Sbjct: 811 QQKVAASMPLSPGGQME------EVAGAVKQISDRGPVRSEDESVEAKRERPSGPESP 862
Score = 47.0 bits (110), Expect = 2e-04
Identities = 68/287 (23%), Positives = 98/287 (34%), Gaps = 47/287 (16%)
Query: 416 PSEPSAPGWWPPPSS--PVPRLPDRPPKEKKKKLPTPAGGPVGTE--------------- 458
P PS P PPPS+ P P P PP LP+P P E
Sbjct: 408 PPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSR 467
Query: 459 -KAAPGIKPSVRKPIQIKKSRPR-----------------EAQPLFPPVRQIVLEGLRSP 500
+ P + PS R + ++ P E P P L+ +R
Sbjct: 468 KRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQF 527
Query: 501 ASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAP---SPSRDSLLPPTQEMRSPSPMTAL 557
V A + + PP+P +P P S P + PSP A
Sbjct: 528 IMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAP 587
Query: 558 QPGSTG-PLPPADDKLEELIRQFEAEFGD-SFGLPGPPSVPIQDPENQQTCLPAPES--P 613
P ST PLP +K ++R+ + + LP PP P P PA S P
Sbjct: 588 TPPSTPVPLP---EKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRP 644
Query: 614 FATRSPKQIKIESSGAV--TVLSTTCFHSEEGGQEATPTKAENPLTP 658
R+P+ E+ + +VL+ + E + P ++P P
Sbjct: 645 LLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEP 691
Score = 43.1 bits (100), Expect = 0.002
Identities = 160/742 (21%), Positives = 243/742 (32%), Gaps = 164/742 (22%)
Query: 103 GPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEWLEGKIKSVVMEG 162
GPR P A E+ QT + +PP D P D V++ G
Sbjct: 1787 GPREEPAHLEAAEEN----QTIVHSPAPSSEPPGGE-DPPLDTD-----------VLVPG 1830
Query: 163 GEER----PRLPGPLPPGEAGLPAPSTRPLLSS--EVPQISPQEGLPLSQSALSIAKEKN 216
ER L PL P P P+ R + +VP SP PL +
Sbjct: 1831 APERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRR-PLGGVSFG------ 1883
Query: 217 ISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPP 276
L + + +LT + P P P L+P P PS PP
Sbjct: 1884 -PLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPP----------PSRWASPP 1932
Query: 277 EEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSAS 336
+ S P PP + T G PP P S P P ++E + G ++
Sbjct: 1933 LKTS---PQLRVPPPTSVVTALTPTSGELAPPG-PAPSPPPPEDLGPDFEDMEVVSGLSA 1988
Query: 337 ---DYIQSVF-------------------------KRPEALPTK-----PKVKVEAPSSS 363
D+ S+ E+ PT P V AP +
Sbjct: 1989 ADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLA 2048
Query: 364 PAPAP-SPVLQR-----EAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPA-- 415
P+ P +P +++ + +E + Q R+ L D + P
Sbjct: 2049 PSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPED 2108
Query: 416 -PSE-----------PSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEK---A 460
PSE P G P S P P + + L P T
Sbjct: 2109 LPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPG 2168
Query: 461 APGI------------KPSVRKPIQIKK------SRPREAQPLFPPVRQIVLEGLRSPAS 502
APG+ KP+ K I + K E +P+ PPV+Q L SP +
Sbjct: 2169 APGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTA 2228
Query: 503 QEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGST 562
PP PL L P + + P+P PP P P+T + S+
Sbjct: 2229 PTSWTLPPGPL---------LGVLPVVGVVRPAP------PP-----PPPPLTLVL--SS 2266
Query: 563 GPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESP-FATRSPKQ 621
GP P + +++ G S P P P D E+ + P+ P + +
Sbjct: 2267 GPASPPRQAIR--VKRVSTFSGRSPPAPPPYKAPRLD-EDGEASEDTPQVPGLGSGGFSR 2323
Query: 622 IKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDT 681
+++++ VL G + P + +PL P + P + D P LL++
Sbjct: 2324 VRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPE---DGPPQVPDGPPDLLLES 2380
Query: 682 -------PAKRAQAEFPTCDCVEQIVEKDEGPYYTHLGSGPTVASI---------RELME 725
A ++ E P+ D E K GP+ S S+ R L+E
Sbjct: 2381 QWHHYSGEASSSEEEPPSPDDKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIE 2440
Query: 726 ERYGEKGKAIRIEKVIYTGKEG 747
+ +G A R+ + ++G G
Sbjct: 2441 KVQEARGHA-RLRHLSFSGMSG 2461
Score = 34.3 bits (77), Expect = 1.0
Identities = 46/183 (25%), Positives = 67/183 (36%), Gaps = 15/183 (8%)
Query: 509 PPAPLPASQGSAVP--LPPEPSLALFAPSPSRDSLLPPTQEMRSPS-----PMTALQPGS 561
PP PLP S P PP P P PS PP QE + S P T +
Sbjct: 413 PPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPP--PPAQEEQEESPPPVVPATCSRKRG 470
Query: 562 TGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQ 621
PL P+ E R G S P P + PE+ T AP+S ++ +Q
Sbjct: 471 RPPLTPSQRAEREAAR--AGPEGTSPPTPTPSTATGGPPEDSPTV--APKSTTFLKNIRQ 526
Query: 622 --IKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLL 679
+ + S+ + V+ T +E + + L P ++ P + P+
Sbjct: 527 FIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRA 586
Query: 680 DTP 682
TP
Sbjct: 587 PTP 589
Score = 33.1 bits (74), Expect = 2.3
Identities = 46/153 (30%), Positives = 54/153 (35%), Gaps = 28/153 (18%)
Query: 493 VLEGLRSPASQEVQAHPPAPL-PASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSP 551
V E + A +E PP PL P + PLPP PS S PP P
Sbjct: 386 VAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPP--------PSTS-----PPPPLCPPP 432
Query: 552 SPMTALQPGSTGPLPPADDKLEELIRQ-FEAEFGDSFGLPGPPSVPIQDPENQQ------ 604
P + P + P PPA ++ EE A G PP P Q E +
Sbjct: 433 PPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRG--RPPLTPSQRAEREAARAGPE 490
Query: 605 -TCLPAPESPFATRSPKQIKIESSGAVTVLSTT 636
T P P AT P E S V STT
Sbjct: 491 GTSPPTPTPSTATGGPP----EDSPTVAPKSTT 519
Score = 32.3 bits (72), Expect = 3.9
Identities = 50/184 (27%), Positives = 65/184 (35%), Gaps = 63/184 (34%)
Query: 503 QEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGST 562
+E +A +PA++ LPP P L PP +PSP L P ST
Sbjct: 381 KEERAVAEEMMPAAEKEEAKLPPPP-------------LTPP-----APSPPPPLPPPST 422
Query: 563 GPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQI 622
P PP L PP P+ P LP+P P P Q
Sbjct: 423 SPPPP---------------------LCPPPPPPVSPPP-----LPSPPPP-----PAQE 451
Query: 623 KIESSGAVTVLSTTCFH---------SEEGGQEATPTKAE--NPLTPTLSGFLESPLKYL 671
+ E S V+ TC S+ +EA E +P TPT S P +
Sbjct: 452 EQEES-PPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPE-- 508
Query: 672 DTPT 675
D+PT
Sbjct: 509 DSPT 512
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 71.2 bits (173), Expect = 8e-12
Identities = 121/459 (26%), Positives = 165/459 (35%), Gaps = 88/459 (19%)
Query: 197 SPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPP 256
SPQ+ S S+ A+++ + Q A++A T ++ A TPQ P P +
Sbjct: 163 SPQDNESDSDSS---AQQQMLQAQPP-ALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATA 218
Query: 257 APFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWP 316
P + + +AP+ P P AP P T +A P P S P
Sbjct: 219 VPPQGSPTASQAPNQPQAPT------AP--------VPHTHIQQA--PALHPQRPPSPHP 262
Query: 317 MPRPSPDPMAELEQLLGSASDYIQSVFKR----------PEALPTKPKVKVEAPSSSPAP 366
P PSP P L+ L GSA + P +L P ++ P P
Sbjct: 263 PPHPSPHP--PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP-PQPFG 319
Query: 367 APSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSA-PGWW 425
P Q +AP +S + T+LQ L +S Q P P P A P
Sbjct: 320 LPPQASQGQAPLGTSPAAAY--PHTSLQ--LPASQSALQSQQPPREQPLPPAPLAMPHIK 375
Query: 426 PPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPI-QIKKSRPREAQP 484
PPP++P+P+L P + K P GP A P KP+ + P A P
Sbjct: 376 PPPTTPIPQL----PAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHP 431
Query: 485 LFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPP--EPSLAL--------FAP 534
PP++ + P SQ + + P P +Q +P PP P L FA
Sbjct: 432 --PPLQLM-------PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 482
Query: 535 SPSRDSLLPPTQEMRSPS-------PMTALQP--------------GSTGPLPPADDKLE 573
P PP PS P T+ QP GS+ PLP K E
Sbjct: 483 HPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEE 542
Query: 574 ELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPES 612
L E E P PP P +P T A +S
Sbjct: 543 ALDDAEEPE-----SPPPPPRSPSPEPTVVDTPSHASQS 576
Score = 66.6 bits (161), Expect = 2e-10
Identities = 103/440 (23%), Positives = 158/440 (35%), Gaps = 60/440 (13%)
Query: 299 PEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVE 358
P+ D +P P S + +Q+L + +Q+ A + P +
Sbjct: 147 PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQ 206
Query: 359 APSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLE-----QVHDTSF 413
P+ P P+ + V + +PT S P+ Q A TA H H +++ L H
Sbjct: 207 LPTPGPTPSATAVPPQGSPTASQAPNQPQ-APTAPVPHTHIQQAPALHPQRPPSPHPPPH 265
Query: 414 PAP-----------SEPSAPGWWPPP----SSPVPRLPDRPPKEKKKKLPTPAG------ 452
P+P +PSAP PP P P P + P P G
Sbjct: 266 PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQAS 325
Query: 453 ---GPVGTEKAAPGIKPSVRKPIQ---IKKSRPREAQPLFP---------PVRQIVLEGL 497
P+GT AA S++ P ++ +P QPL P P + L
Sbjct: 326 QGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQL 385
Query: 498 RSPASQEVQAHPPAPLPASQGSAVPLPPE----PSLALFAP---SPSRDSLLPPTQEM-R 549
+P + + H P P S + +P PP SL+ P P L+P +Q +
Sbjct: 386 PAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS 445
Query: 550 SPSPMTALQPGSTGPLPPADDKLEELIRQF-EAEFGDSFGLPGPPSVPIQDPENQQTCLP 608
SP+ L P PPA L + + F +PG P PI P T P
Sbjct: 446 SPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP-PITPPTCPSTSTP 504
Query: 609 APESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPL 668
P P + P +SG ++C +E AE P +P P
Sbjct: 505 -PAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESP-------PPP 556
Query: 669 KYLDTPTKSLLDTPAKRAQA 688
+P +++DTP+ +Q+
Sbjct: 557 PRSPSPEPTVVDTPSHASQS 576
Score = 64.3 bits (155), Expect = 9e-10
Identities = 102/417 (24%), Positives = 142/417 (34%), Gaps = 61/417 (14%)
Query: 170 PGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALT 229
P PPG LP P P ++ PQ SP +Q A + +Q A A+
Sbjct: 197 PSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH--P 254
Query: 230 QLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFA------ 283
Q + P H +P P + L+ A S S+ + P PP HS A
Sbjct: 255 QRPPSPHPPPHPSPH---PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH 311
Query: 284 ---PDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQ 340
P PP + + P GT A P +S +P A L Q
Sbjct: 312 PGPPQPFGLPPQASQGQAP--LGTSPAAAYPHTSLQLP-------ASQSALQSQQPPREQ 362
Query: 341 SVFKRPEALPTKPKVKVEAPSSSPAP-APSPVLQREAPTPSSEPDTHQKAQTALQQHLHH 399
+ P A+P ++ P ++P P P+P + P S A L
Sbjct: 363 PLPPAPLAMP-----HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP 417
Query: 400 KRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPP-KEKKKKLPTPAGG--PVG 456
SL T P PS P P S P+P P +PP + + LP P P G
Sbjct: 418 LSSL------STHHP-PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTG 470
Query: 457 TEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPAS 516
+ AP + P P P+ PP PA A PP A+
Sbjct: 471 LHQVAP------QPPFAQHPFVPGGPPPITPPT---CPSTSTPPAGPGTSAQPPCSGAAA 521
Query: 517 QGSAV---PLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD 570
G ++ P P++ + ++ L +E SP P P S P P D
Sbjct: 522 SGGSIAGGSSCPLPTVQI------KEEALDDAEEPESPPP----PPRSPSPEPTVVD 568
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 71.2 bits (173), Expect = 8e-12
Identities = 121/459 (26%), Positives = 165/459 (35%), Gaps = 88/459 (19%)
Query: 197 SPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPP 256
SPQ+ S S+ A+++ + Q A++A T ++ A TPQ P P +
Sbjct: 717 SPQDNESDSDSS---AQQQMLQAQPP-ALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATA 772
Query: 257 APFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWP 316
P + + +AP+ P P AP P T +A P P S P
Sbjct: 773 VPPQGSPTASQAPNQPQAPT------AP--------VPHTHIQQA--PALHPQRPPSPHP 816
Query: 317 MPRPSPDPMAELEQLLGSASDYIQSVFKR----------PEALPTKPKVKVEAPSSSPAP 366
P PSP P L+ L GSA + P +L P ++ P P
Sbjct: 817 PPHPSPHP--PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP-PQPFG 873
Query: 367 APSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSA-PGWW 425
P Q +AP +S + T+LQ L +S Q P P P A P
Sbjct: 874 LPPQASQGQAPLGTSPAAAY--PHTSLQ--LPASQSALQSQQPPREQPLPPAPLAMPHIK 929
Query: 426 PPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPI-QIKKSRPREAQP 484
PPP++P+P+L P + K P GP A P KP+ + P A P
Sbjct: 930 PPPTTPIPQL----PAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHP 985
Query: 485 LFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPP--EPSLAL--------FAP 534
PP++ + P SQ + + P P +Q +P PP P L FA
Sbjct: 986 --PPLQLM-------PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 1036
Query: 535 SPSRDSLLPPTQEMRSPS-------PMTALQP--------------GSTGPLPPADDKLE 573
P PP PS P T+ QP GS+ PLP K E
Sbjct: 1037 HPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEE 1096
Query: 574 ELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPES 612
L E E P PP P +P T A +S
Sbjct: 1097 ALDDAEEPE-----SPPPPPRSPSPEPTVVDTPSHASQS 1130
Score = 66.6 bits (161), Expect = 2e-10
Identities = 103/440 (23%), Positives = 158/440 (35%), Gaps = 60/440 (13%)
Query: 299 PEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVE 358
P+ D +P P S + +Q+L + +Q+ A + P +
Sbjct: 701 PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQ 760
Query: 359 APSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLE-----QVHDTSF 413
P+ P P+ + V + +PT S P+ Q A TA H H +++ L H
Sbjct: 761 LPTPGPTPSATAVPPQGSPTASQAPNQPQ-APTAPVPHTHIQQAPALHPQRPPSPHPPPH 819
Query: 414 PAP-----------SEPSAPGWWPPP----SSPVPRLPDRPPKEKKKKLPTPAG------ 452
P+P +PSAP PP P P P + P P G
Sbjct: 820 PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQAS 879
Query: 453 ---GPVGTEKAAPGIKPSVRKPIQ---IKKSRPREAQPLFP---------PVRQIVLEGL 497
P+GT AA S++ P ++ +P QPL P P + L
Sbjct: 880 QGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQL 939
Query: 498 RSPASQEVQAHPPAPLPASQGSAVPLPPE----PSLALFAP---SPSRDSLLPPTQEM-R 549
+P + + H P P S + +P PP SL+ P P L+P +Q +
Sbjct: 940 PAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS 999
Query: 550 SPSPMTALQPGSTGPLPPADDKLEELIRQF-EAEFGDSFGLPGPPSVPIQDPENQQTCLP 608
SP+ L P PPA L + + F +PG P PI P T P
Sbjct: 1000 SPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP-PITPPTCPSTSTP 1058
Query: 609 APESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPL 668
P P + P +SG ++C +E AE P +P P
Sbjct: 1059 -PAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESP-------PPP 1110
Query: 669 KYLDTPTKSLLDTPAKRAQA 688
+P +++DTP+ +Q+
Sbjct: 1111 PRSPSPEPTVVDTPSHASQS 1130
Score = 64.3 bits (155), Expect = 9e-10
Identities = 102/417 (24%), Positives = 142/417 (34%), Gaps = 61/417 (14%)
Query: 170 PGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALT 229
P PPG LP P P ++ PQ SP +Q A + +Q A A+
Sbjct: 751 PSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH--P 808
Query: 230 QLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFA------ 283
Q + P H +P P + L+ A S S+ + P PP HS A
Sbjct: 809 QRPPSPHPPPHPSPH---PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH 865
Query: 284 ---PDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQ 340
P PP + + P GT A P +S +P A L Q
Sbjct: 866 PGPPQPFGLPPQASQGQAP--LGTSPAAAYPHTSLQLP-------ASQSALQSQQPPREQ 916
Query: 341 SVFKRPEALPTKPKVKVEAPSSSPAP-APSPVLQREAPTPSSEPDTHQKAQTALQQHLHH 399
+ P A+P ++ P ++P P P+P + P S A L
Sbjct: 917 PLPPAPLAMP-----HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP 971
Query: 400 KRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPP-KEKKKKLPTPAGG--PVG 456
SL T P PS P P S P+P P +PP + + LP P P G
Sbjct: 972 LSSL------STHHP-PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTG 1024
Query: 457 TEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPAS 516
+ AP + P P P+ PP PA A PP A+
Sbjct: 1025 LHQVAP------QPPFAQHPFVPGGPPPITPPT---CPSTSTPPAGPGTSAQPPCSGAAA 1075
Query: 517 QGSAV---PLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD 570
G ++ P P++ + ++ L +E SP P P S P P D
Sbjct: 1076 SGGSIAGGSSCPLPTVQI------KEEALDDAEEPESPPP----PPRSPSPEPTVVD 1122
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 71.2 bits (173), Expect = 8e-12
Identities = 121/459 (26%), Positives = 165/459 (35%), Gaps = 88/459 (19%)
Query: 197 SPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPP 256
SPQ+ S S+ A+++ + Q A++A T ++ A TPQ P P +
Sbjct: 717 SPQDNESDSDSS---AQQQMLQAQPP-ALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATA 772
Query: 257 APFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWP 316
P + + +AP+ P P AP P T +A P P S P
Sbjct: 773 VPPQGSPTASQAPNQPQAPT------AP--------VPHTHIQQA--PALHPQRPPSPHP 816
Query: 317 MPRPSPDPMAELEQLLGSASDYIQSVFKR----------PEALPTKPKVKVEAPSSSPAP 366
P PSP P L+ L GSA + P +L P ++ P P
Sbjct: 817 PPHPSPHP--PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP-PQPFG 873
Query: 367 APSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSA-PGWW 425
P Q +AP +S + T+LQ L +S Q P P P A P
Sbjct: 874 LPPQASQGQAPLGTSPAAAY--PHTSLQ--LPASQSALQSQQPPREQPLPPAPLAMPHIK 929
Query: 426 PPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPI-QIKKSRPREAQP 484
PPP++P+P+L P + K P GP A P KP+ + P A P
Sbjct: 930 PPPTTPIPQL----PAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHP 985
Query: 485 LFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPP--EPSLAL--------FAP 534
PP++ + P SQ + + P P +Q +P PP P L FA
Sbjct: 986 --PPLQLM-------PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 1036
Query: 535 SPSRDSLLPPTQEMRSPS-------PMTALQP--------------GSTGPLPPADDKLE 573
P PP PS P T+ QP GS+ PLP K E
Sbjct: 1037 HPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEE 1096
Query: 574 ELIRQFEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPES 612
L E E P PP P +P T A +S
Sbjct: 1097 ALDDAEEPE-----SPPPPPRSPSPEPTVVDTPSHASQS 1130
Score = 66.6 bits (161), Expect = 2e-10
Identities = 103/440 (23%), Positives = 158/440 (35%), Gaps = 60/440 (13%)
Query: 299 PEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVE 358
P+ D +P P S + +Q+L + +Q+ A + P +
Sbjct: 701 PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQ 760
Query: 359 APSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLE-----QVHDTSF 413
P+ P P+ + V + +PT S P+ Q A TA H H +++ L H
Sbjct: 761 LPTPGPTPSATAVPPQGSPTASQAPNQPQ-APTAPVPHTHIQQAPALHPQRPPSPHPPPH 819
Query: 414 PAP-----------SEPSAPGWWPPP----SSPVPRLPDRPPKEKKKKLPTPAG------ 452
P+P +PSAP PP P P P + P P G
Sbjct: 820 PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQAS 879
Query: 453 ---GPVGTEKAAPGIKPSVRKPIQ---IKKSRPREAQPLFP---------PVRQIVLEGL 497
P+GT AA S++ P ++ +P QPL P P + L
Sbjct: 880 QGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQL 939
Query: 498 RSPASQEVQAHPPAPLPASQGSAVPLPPE----PSLALFAP---SPSRDSLLPPTQEM-R 549
+P + + H P P S + +P PP SL+ P P L+P +Q +
Sbjct: 940 PAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS 999
Query: 550 SPSPMTALQPGSTGPLPPADDKLEELIRQF-EAEFGDSFGLPGPPSVPIQDPENQQTCLP 608
SP+ L P PPA L + + F +PG P PI P T P
Sbjct: 1000 SPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP-PITPPTCPSTSTP 1058
Query: 609 APESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAENPLTPTLSGFLESPL 668
P P + P +SG ++C +E AE P +P P
Sbjct: 1059 -PAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESP-------PPP 1110
Query: 669 KYLDTPTKSLLDTPAKRAQA 688
+P +++DTP+ +Q+
Sbjct: 1111 PRSPSPEPTVVDTPSHASQS 1130
Score = 64.3 bits (155), Expect = 9e-10
Identities = 102/417 (24%), Positives = 142/417 (34%), Gaps = 61/417 (14%)
Query: 170 PGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALT 229
P PPG LP P P ++ PQ SP +Q A + +Q A A+
Sbjct: 751 PSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH--P 808
Query: 230 QLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFA------ 283
Q + P H +P P + L+ A S S+ + P PP HS A
Sbjct: 809 QRPPSPHPPPHPSPH---PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH 865
Query: 284 ---PDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQ 340
P PP + + P GT A P +S +P A L Q
Sbjct: 866 PGPPQPFGLPPQASQGQAP--LGTSPAAAYPHTSLQLP-------ASQSALQSQQPPREQ 916
Query: 341 SVFKRPEALPTKPKVKVEAPSSSPAP-APSPVLQREAPTPSSEPDTHQKAQTALQQHLHH 399
+ P A+P ++ P ++P P P+P + P S A L
Sbjct: 917 PLPPAPLAMP-----HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP 971
Query: 400 KRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPP-KEKKKKLPTPAGG--PVG 456
SL T P PS P P S P+P P +PP + + LP P P G
Sbjct: 972 LSSL------STHHP-PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTG 1024
Query: 457 TEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPAS 516
+ AP + P P P+ PP PA A PP A+
Sbjct: 1025 LHQVAP------QPPFAQHPFVPGGPPPITPPT---CPSTSTPPAGPGTSAQPPCSGAAA 1075
Query: 517 QGSAV---PLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADD 570
G ++ P P++ + ++ L +E SP P P S P P D
Sbjct: 1076 SGGSIAGGSSCPLPTVQI------KEEALDDAEEPESPPP----PPRSPSPEPTVVD 1122
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 70.1 bits (170), Expect = 2e-11
Identities = 130/517 (25%), Positives = 182/517 (35%), Gaps = 97/517 (18%)
Query: 162 GGEERP-RLPGPLPPGEAGLPAPSTRPLLSSEV---PQISPQEGLPLSQSALSIAKEKNI 217
GG RP R P +G + S P L + P SP + P ++ +
Sbjct: 565 GGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGA 624
Query: 218 SLQTAIAIEALTQL--SSALPQPS-HSTPQASCPL------PEALSPPAPFRSPQSYLRA 268
S+ ++ LT L SS+ P PS S PQ PL P PAPF P S R+
Sbjct: 625 SVSSS-----LTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRS 679
Query: 269 PSWPVVPPEEHSSFAP------DSSAFPPATPRT------EFPEAWGTDTPPATPRSSW- 315
P+ P P + P D+S P TP+T E P +PP +P S+
Sbjct: 680 PN-PAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYH 738
Query: 316 PMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSS---PAP------ 366
P P P+ P +E SAS+ + + P P P E S P P
Sbjct: 739 PPPPPTKKPEVVVE--APSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFS 796
Query: 367 --APSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGW 424
+P P +P S P + TAL Q+ P P P+ P
Sbjct: 797 VASPEPAGPSGSPELVSSPAASSSSATAL-------------QIQPPGSPDP-PPAPPAP 842
Query: 425 WPPPSSP--VPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREA 482
P S+P V +LP + P K GGP + AP + PS+ + ++++
Sbjct: 843 APASSAPGHVAKLPQKEPVGCSK-----GGGPPREDVGAPLVTPSLLQMVRLRS----VG 893
Query: 483 QPLFPPVRQIVLEGLRSPASQEVQAH-PPAPLPASQGSAVPLPPEPSLALFAPSPSRDSL 541
P P + + P + + P P P+S A SLA S
Sbjct: 894 APGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPN 953
Query: 542 LPPTQEMRSPSPMTALQPGSTGPL-------------PPADDKLEELIRQFEAEFGDSFG 588
PP E R P P ST P + + +L R AE S
Sbjct: 954 GPPEAEPRPPQ-----SPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAEL-RSIS 1007
Query: 589 LPGPPSVPIQDPE-------NQQTCLPAPESPFATRS 618
PP P + P+ +P P SP R+
Sbjct: 1008 EQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRA 1044
Score = 68.6 bits (166), Expect = 5e-11
Identities = 101/378 (26%), Positives = 137/378 (36%), Gaps = 68/378 (17%)
Query: 255 PPAPFRSP---QSYLRAPSWPV-VPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPAT 310
PP P R+ Q L P P+ +PP+ P P P T E G P
Sbjct: 498 PPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQL----PRPPTTGGSEGAGAAPCPPN 553
Query: 311 PRSSWP---MPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPA 367
P +SW P S P E+ L +S Y PT P + P +SP A
Sbjct: 554 PANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQ-----SGTPTLPPKGLAGPPASPGKA 608
Query: 368 PSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPP 427
P +R T+L+ S +S PAPS+ S P P
Sbjct: 609 QPPKPERV---------------TSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTP 653
Query: 428 -------PSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPR 480
P P P PP K + P PA + AAP + P P+
Sbjct: 654 LGDRFVIPPHPKVPAPFSPPPSKPRS-PNPAAPAL----AAPAVVPG---PVSTT----- 700
Query: 481 EAQPLFPPVRQIVLEGLR-SPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRD 539
+A P PP Q L L+ SP + Q+ PP+P P S P +P + + APS S +
Sbjct: 701 DASPQSPPTPQTTLTPLQESPVISKDQSPPPSP-PPSYHPPPPPTKKPEVVVEAPSAS-E 758
Query: 540 SLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGP-PSVPIQ 598
+ P Q+ P P PPA ++ + + F F + P P+ P
Sbjct: 759 TAEEPLQDPNWPPPP-----------PPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSG 807
Query: 599 DPENQQTCLPAPESPFAT 616
PE + PA S AT
Sbjct: 808 SPELVSS--PAASSSSAT 823
Score = 50.8 bits (120), Expect = 1e-05
Identities = 108/451 (23%), Positives = 162/451 (35%), Gaps = 72/451 (15%)
Query: 166 RPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAI 225
+PR P P P A PA P+ +++ SP P Q+ L+ +E + +
Sbjct: 676 KPRSPNPAAPALAA-PAVVPGPVSTTDASPQSP----PTPQTTLTPLQESPVISKD---- 726
Query: 226 EALTQLSSALPQPSHSTPQASCPLPEAL-SPPAPFRSPQSYLRAPSWPVVPPEEHSSFAP 284
Q P PS+ P PE + P+ + + L+ P+WP PP AP
Sbjct: 727 ----QSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPP-----AP 777
Query: 285 DSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPS-PDPMAELEQLLGSASDYIQSVF 343
+ A +FP PP S P P+ P EL ++S
Sbjct: 778 EEQDLSMA----DFP-------PPEEAFFSVASPEPAGPSGSPELVSSPAASS------- 819
Query: 344 KRPEALPTKPKVKVEAPSSSPAPAP-SPVLQREAPTPSSEPDTHQKAQTALQQHLHHK-- 400
AL +P + P + PAPAP S A P EP K ++ +
Sbjct: 820 SSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLV 879
Query: 401 RSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKA 460
L+ V S APG P P+ P P +P + +P P A
Sbjct: 880 TPSLLQMVRLRSV------GAPGGAPTPALG-PSAPQKPLRRALSGRASPVPAPSSGLHA 932
Query: 461 APGIKP-SVRKPIQIKKSRPR---EAQPLFPP-------------VRQIVLEGLRSPASQ 503
A +K S+ + ++P EA+P P R++ LE SP +Q
Sbjct: 933 AVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQ 992
Query: 504 -EVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSL-LPPTQEMRSPSPMTALQPGS 561
++Q + A L + P P+ S P + S+ +PP P P +
Sbjct: 993 ADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPT 1052
Query: 562 TGPLPPADDKLEELIRQFEAEFGDSFGLPGP 592
G LP D+ + + AE G L GP
Sbjct: 1053 NG-LPHTQDRTKREL----AENGGVLQLVGP 1078
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 69.3 bits (168), Expect = 3e-11
Identities = 92/428 (21%), Positives = 138/428 (32%), Gaps = 85/428 (19%)
Query: 181 PAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSH 240
P+P+ P L E ++ P ++LS E+ T ++ T SS + + S
Sbjct: 1086 PSPTPLPTLPKE---LTSDPSTPSEVTSLSPTSEQVPESDTTPDLDT-TPYSSTVSEYSR 1141
Query: 241 STPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAF--------PPA 292
S + P P P P + L P P H + P + P
Sbjct: 1142 SPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTT 1201
Query: 293 TPR--------------TEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDY 338
TP+ T P+ + T P TP S+ P P +P P + S
Sbjct: 1202 TPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTI------THSTM 1255
Query: 339 IQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLH 398
I P+ T + P+++P P +P PT + P T
Sbjct: 1256 IPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTP-----HPTTTPHPTT------------- 1297
Query: 399 HKRSLFLEQVHDTSFPAPSEPSAPGWWP-PPSSPVPRLPD--RPPKEKKKKLPTPAGGPV 455
H T P P+ P P P ++P P PD P LPT G +
Sbjct: 1298 --------TPHPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTEL 1349
Query: 456 GTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVR-------------------QIVLEG 496
+ AP +KPS+ + P + P + + E
Sbjct: 1350 SSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTED 1409
Query: 497 LRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTA 556
+ P SQ PP S + + P+P L SP+ L P + + P
Sbjct: 1410 FKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLL-----SPTAHPLDHPPLDPLTLGPTPG 1464
Query: 557 LQPGSTGP 564
PG GP
Sbjct: 1465 QSPGPHGP 1472
Score = 45.8 bits (107), Expect = 3e-04
Identities = 113/556 (20%), Positives = 169/556 (30%), Gaps = 125/556 (22%)
Query: 98 GNNSRGPRPGP-----EGCSAGSEDLDTLQTALALARHGM---KPPNCNCDG-PECPDYL 148
G GP GP GC L + A +H + C G + DY
Sbjct: 823 GKTHYGPGTGPIWLDDMGCKGSEASLSDCPSG-AWGKHNCDHEEDVGLTCTGYTDYDDYP 881
Query: 149 EWLEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPL---- 204
W + G +PG P S+ P + +P ++G L
Sbjct: 882 PWTWDPTSREDLAKGTTTAGVPGHTLPWRTTRRPGSSSPAIR-RLPDTGSKDGYKLPWTW 940
Query: 205 -SQSALSIAKEKNISLQTAIAIEALTQLSSALP----------QPSHSTPQASCPLPEAL 253
+ S +A+ + + + A T S P P P+ P P A
Sbjct: 941 DTPSGRGLAEGTPTAGKLGPTLGAGTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAAT 1000
Query: 254 --SPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATP 311
+PP P P S P P + + P S+ AT +D P +P
Sbjct: 1001 RTAPPTPSPGP-SASPGPPGPALTSDSSRELTPHSALTSEAT----------SDAPDTSP 1049
Query: 312 RSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPV 371
+ P R +PD L+ ++ D+ AL T V A + P+P P P
Sbjct: 1050 PTPDPASRTNPD-------LILTSPDF---------ALSTPDSSVVPALTPEPSPTPLPT 1093
Query: 372 LQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSP 431
L +E + S P + + TS P + P P S
Sbjct: 1094 LPKELTSDPSTPSE-------------------VTSLSPTSEQVPESDTTPDLDTTPYSS 1134
Query: 432 VPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQ 491
R P PT P + P+V P FP
Sbjct: 1135 TVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTV--------------TPHFP---- 1176
Query: 492 IVLEGLRSPASQEVQAHP---PAPLPASQGSAVPLP---PEPSLALFAPSPSRDSLLP-P 544
HP P P + + +P P P+P + + +++P P
Sbjct: 1177 -------------TTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTI-----THSTMIPDP 1218
Query: 545 TQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPSVPIQDPENQQ 604
T +P P T +QP +T P S +P P + P Q
Sbjct: 1219 T---TTPQPFTTMQPTTT----PHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQP 1271
Query: 605 TCLPAP-ESPFATRSP 619
T +P P +P T +P
Sbjct: 1272 TTMPHPTTTPHPTTTP 1287
Score = 34.7 bits (78), Expect = 0.79
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 272 PVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQL 331
P P + ++S ++++ PP+T ++ P G PPA+P W P P A QL
Sbjct: 413 PTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLW-----EPGPEAGSPQL 467
>gi|116063558 tet oncogene family member 2 isoform b [Homo sapiens]
Length = 1165
Score = 67.8 bits (164), Expect = 8e-11
Identities = 40/91 (43%), Positives = 50/91 (54%), Gaps = 14/91 (15%)
Query: 617 RSPKQIKIESSGAVTVLS-----------TTCFHSEEGGQEATPTKAENPLTPTLSGFLE 665
+S KQ+K+E SG VTVL+ T + E TPTK L+ F+E
Sbjct: 1049 KSQKQVKVEMSGPVTVLTRQTTAAELDSHTPALEQQTTSSEKTPTK--RTAASVLNNFIE 1106
Query: 666 SPLKYLDTPTKSLLDTPAKRAQAEFPTCDCV 696
SP K LDTP K+LLDTP K Q +FP+C CV
Sbjct: 1107 SPSKLLDTPIKNLLDTPVK-TQYDFPSCRCV 1136
Score = 32.3 bits (72), Expect = 3.9
Identities = 39/133 (29%), Positives = 54/133 (40%), Gaps = 26/133 (19%)
Query: 138 NCDGPECPDY--LEWLEGKI-----KSVVMEGGEERPRLPGPLPPGEAGLPAPSTR---- 186
NC GPE P+ L EGK K++V+ + L P A + A S
Sbjct: 170 NCSGPENPELQILNEQEGKSANYHDKNIVLLKNK------AVLMPNGATVSASSVEHTHG 223
Query: 187 PLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQA- 245
LL + Q P +SIA +K S AI +A +LS + PSH++ Q
Sbjct: 224 ELLEKTLSQYYPD--------CVSIAVQKTTSHINAINSQATNELSCEITHPSHTSGQIN 275
Query: 246 SCPLPEALSPPAP 258
S + PP P
Sbjct: 276 SAQTSNSELPPKP 288
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 67.8 bits (164), Expect = 8e-11
Identities = 139/555 (25%), Positives = 193/555 (34%), Gaps = 101/555 (18%)
Query: 168 RLPGPLPPGEAGLPAPSTRPLLSSE--VPQISPQE-GLPLSQSALSIAKEKNISLQTAIA 224
R P P P + GL T SE +P SP L S+S + +E S+
Sbjct: 98 RPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFL 157
Query: 225 IE--ALTQLSSALP-------------------------QPSHSTPQASCPLPEALSPPA 257
E AL+ +SS + Q P+ P PP
Sbjct: 158 SEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPK 217
Query: 258 PFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPM 317
P Q R P P+ SS P+ P P T P T TP T + P+
Sbjct: 218 PIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQP--PGTGKPIQGPTQTPQ-TDHAKLPL 274
Query: 318 PRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAP 377
R + P + +D ++ +P +LP+ K ++ P+ PA P ++ P
Sbjct: 275 QRDASRPQTK-------QADIVRGESVKP-SLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326
Query: 378 TPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPP-------PSS 430
P+ P L Q + Q T+ P P++P P P PSS
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPV--QPPGTTKP-PAQPLGPAKPPAQQTGSEKPSS 383
Query: 431 --PVPRLPDRPPKEKKK--KLPTPAGGP---VGTEKAA---PGIKPSVRKP----IQIKK 476
P P+ +PP K + P PA P VGT K PG++ + P +++
Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ 443
Query: 477 SRPRE--AQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAP 534
P + AQ P G P SQ P P P G A P P +P A P
Sbjct: 444 PGPGKIPAQQAGPGKTSAQQTGPTKPPSQ--LPGPAKPPPQQPGPAKPPPQQPGSAK-PP 500
Query: 535 SPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPS 594
S S PP Q+ P+ + QPGST PP+ PG
Sbjct: 501 SQQPGSTKPPPQQ-PGPAKPSPQQPGST--KPPSQQ-------------------PGSAK 538
Query: 595 VPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAEN 654
P QQ P+P P A +S K + SG T +++ + P K
Sbjct: 539 -----PSAQQ---PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP-KTIC 589
Query: 655 PLTPTLSGFLESPLK 669
PL T L P K
Sbjct: 590 PLCNTTELLLHVPEK 604
Score = 56.6 bits (135), Expect = 2e-07
Identities = 133/578 (23%), Positives = 196/578 (33%), Gaps = 121/578 (20%)
Query: 142 PECPDYLEWLEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAP-STRPLLSSEVPQISPQE 200
P + EWL + GG+ P P P + AP +T +S PQ PQ+
Sbjct: 627 PHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT---APVTTTSAVSKSSPQ--PQQ 681
Query: 201 GLPLSQSA----LSIAKEKNISLQTAIAIEALTQLSSALPQPS-HSTPQASCPLP---EA 252
P +A LS A E + + QP+ H +P A P ++
Sbjct: 682 TSPKKDAAPKQDLSKAPEPK-------------KPPPLVKQPTLHGSPSAKAKQPPEADS 728
Query: 253 LSPPAPFRSPQSYLRAPSWPVVP--PEEHSSFAP--DSSAFPPATPRTEFP------EAW 302
LS PAP + P PV P++ P D + AT + + P +A
Sbjct: 729 LSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE 788
Query: 303 GTDTPP-----ATPRSSWP-------------MPRPSPD------PMAELEQLLGSASDY 338
TPP A P S+P +PRP+ D P E D
Sbjct: 789 EKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDP 848
Query: 339 IQSVFKRPEALPTKPKVKVEA---PSSSPAP-APSPVLQREAPTPSSEP----------- 383
+Q + P+ TK K +A P SP P P P + PTP P
Sbjct: 849 VQKK-EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSL 907
Query: 384 ------DTHQKAQTALQQHLHHK-----RSLFLEQ---VHDTSFPAPSEPSAPGWWPPPS 429
D + T Q+ + K S+F + + P P S PG P
Sbjct: 908 NLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG-APMKQ 966
Query: 430 SPVPRLP---DRPPKEKKKKLPTPAGG-PVGTEKAAPGIKPSVRKPIQIKKSRPREAQPL 485
+P P P PPK + P PA PV E AP + K Q + E +
Sbjct: 967 APAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKK 1026
Query: 486 FPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPT 545
PP++ S+ + A P + ++ P PE + L + S PP
Sbjct: 1027 PPPIKD----------SKSLTAEPQKAVLPTKLEKSP-KPESTCPLCKTELNIGSKDPPN 1075
Query: 546 QEMRSPSPMTALQPGSTGPLPPADDKLEELI------RQFEAEFGDSFGLPGPPSVPIQD 599
+ P P + E L R + GD +P PS P
Sbjct: 1076 FNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKAS 1135
Query: 600 P-------ENQQTCLPAPESPFATRSPKQIKIESSGAV 630
P +Q+T +P P+ + +++K E+ +
Sbjct: 1136 PMPVPTESSSQKTAVP-PQVKLVKKQEQEVKTEAEKVI 1172
Score = 48.9 bits (115), Expect = 4e-05
Identities = 111/570 (19%), Positives = 174/570 (30%), Gaps = 130/570 (22%)
Query: 159 VMEGGEERPRLPGPL-PPGEAGLPAPSTRPLLSSEVPQISPQE------GL--PLSQSAL 209
++ G +P LP P PP + P E Q P + GL PL+Q
Sbjct: 288 IVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPG 347
Query: 210 SIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAP 269
++ T + L Q P + P P+AL+ P P
Sbjct: 348 TVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP------------P 395
Query: 270 SWPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPR-SSWPMPRPSPDPMAEL 328
P ++ P + P + P G +P P + P+ +P P +
Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQP---GLQSPAKAPGPTKTPVQQPGPGKIPAQ 452
Query: 329 EQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQK 388
+ G S + PTKP ++ P+ P P P S++P + Q
Sbjct: 453 QAGPGKTS--------AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504
Query: 389 AQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLP--DRPPKEKKKK 446
T P P +P P+ P P+ P +PP ++
Sbjct: 505 GSTK---------------------PPPQQPG-------PAKPSPQQPGSTKPPSQQPGS 536
Query: 447 LPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPA----- 501
A P A P + S + Q +P + + P +Q +GL
Sbjct: 537 AKPSAQQP---SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCN 593
Query: 502 SQEVQAHPPA---------------------PLP-----------------ASQGSAVPL 523
+ E+ H P P P A G P+
Sbjct: 594 TTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPV 653
Query: 524 P--PEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQ--- 578
P P+P L AP + ++ + + + SP P P K L++Q
Sbjct: 654 PSSPQPKLKT-APVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712
Query: 579 --------FEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV 630
+ DS P PP P E ++P A PKQ K+
Sbjct: 713 HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQD-------KAPVADDKPKQPKMVKPTTD 765
Query: 631 TVLSTTCFHSEEGGQEATPTKAENPLTPTL 660
V S++ + ++AE TP L
Sbjct: 766 LVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795
Score = 43.5 bits (101), Expect = 0.002
Identities = 80/353 (22%), Positives = 130/353 (36%), Gaps = 63/353 (17%)
Query: 219 LQTAIAIEALTQLSSALPQPSHSTPQASCP-LPEALSP------PAPFRSPQSYLRAPSW 271
+Q IA E+L S + + S P + P L ++S +P + S +
Sbjct: 2153 IQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTE 2212
Query: 272 PV--VPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELE 329
PV + E S S+ FP + ++PE P PD A +
Sbjct: 2213 PVDMITKFEDSEEISSSTYFPGSI--IDYPEEISVSLDRTAP----------PDGRASAD 2260
Query: 330 QLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKA 389
++ S SD S+ E++ KP+ V S+ ++ + P ++ +T
Sbjct: 2261 HIVISLSDMASSII---ESVVPKPEGPVADTVSTDL-----LISEKDPVKKAKKETGNGI 2312
Query: 390 QTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPT 449
+ + K+ L E+ S S + PPSS + P KE+
Sbjct: 2313 ILEVLEAYRDKKELEAERTK-------SSLSETVFDHPPSSVIAL----PMKEQLSTTYF 2361
Query: 450 PAGGPVGTEKAA---PGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQ 506
+G G EK A P PSV S P + +P F +S ++
Sbjct: 2362 TSGETFGQEKPASQLPSGSPSV-------SSLPAKPRPFF------------RSSSLDIS 2402
Query: 507 AHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQP 559
A PP P P P PP P L P+ + ++L P +++ SP+T P
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTIL-PKKKLTVASPVTTATP 2454
Score = 40.8 bits (94), Expect = 0.011
Identities = 56/204 (27%), Positives = 67/204 (32%), Gaps = 36/204 (17%)
Query: 426 PPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPL 485
PPP P P P PP LP P P T P K +V P+ A PL
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPPLPPPTS-PKPT--ILPKKKLTVASPVTT-------ATPL 2455
Query: 486 FPPVRQI----VLEGLRSPASQEVQAHPPA--PLPASQGSAVPLP--PEPSLALFAPSPS 537
F V + VL P ++ PP P P+S S + PEPS AP P
Sbjct: 2456 FDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPV 2515
Query: 538 RDSLLPPTQEMRSPSPM-TALQ-----------------PGSTGPLPPADDKLEELIRQF 579
L TQ+ P T L P T PL P +K +
Sbjct: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
Query: 580 EAEFGDSFGLPGPPSVPIQDPENQ 603
E LP P P +Q
Sbjct: 2576 LTETYVVITLPSEPGTPTDSSASQ 2599
Score = 37.4 bits (85), Expect = 0.12
Identities = 37/136 (27%), Positives = 65/136 (47%), Gaps = 13/136 (9%)
Query: 959 TKEDNRCVGKIPEDEQLHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLP 1018
T+ + + K+ E + +P M TD+ EE++ K + A+Q P E + +P
Sbjct: 1166 TEAEKVILEKVKETLSMEKIP--PMVTTDQ-KQEESKLEKDKASALQEKKPLPEEKKLIP 1222
Query: 1019 EPAKSCRQRQ---LEARKAAAEKKKIQKE-KLSTPEKIKQEALELAGITSDPGLSLKGGL 1074
E K + + LE +K E KK+ E K S PE+ K + L+ ++ L+G +
Sbjct: 1223 EEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEE--KLEGRV 1280
Query: 1075 S----QQGLKPSLKVE 1086
+ Q+G +P K+E
Sbjct: 1281 APKTVQEGKQPQTKME 1296
Score = 37.4 bits (85), Expect = 0.12
Identities = 62/253 (24%), Positives = 84/253 (33%), Gaps = 25/253 (9%)
Query: 180 LPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPS 239
L A T+ LS V P S +++ ++ +S + E Q A PS
Sbjct: 2326 LEAERTKSSLSETVFDHPPS-------SVIALPMKEQLSTTYFTSGETFGQEKPASQLPS 2378
Query: 240 HSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPRTEFP 299
S +S P + P PF S + P PP P PP P P
Sbjct: 2379 GSPSVSSLP-----AKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433
Query: 300 EAWGTDTPPATPRSSWPMPRPSPDPMAELEQ---LLGSASDYIQSVFKRPEALPTKPK-- 354
+ T S P D + LE L + + P +P KP
Sbjct: 2434 KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI 2493
Query: 355 ----VKVEAPSSSPAP-APSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVH 409
V P S P AP PV+ + T D H K T L L +L L
Sbjct: 2494 PSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPK-PTGLS--LTSSMTLNLVTSA 2550
Query: 410 DTSFPAPSEPSAP 422
D P+P+ P +P
Sbjct: 2551 DYKLPSPTSPLSP 2563
Score = 33.9 bits (76), Expect = 1.4
Identities = 93/419 (22%), Positives = 132/419 (31%), Gaps = 83/419 (19%)
Query: 291 PATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALP 350
P+ T P + DTP T S S P+ L D I +V+ P +
Sbjct: 2169 PSESATSVPPS---DTPSLTSSVSSVCTTDSSSPITTL--------DSITTVYTEPVDMI 2217
Query: 351 TKPKVKVEAPSSSPAPAP--------SPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRS 402
TK + E SS+ P S L R AP PD A H+ S
Sbjct: 2218 TKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAP-----PDGRASAD-----HIVISLS 2267
Query: 403 LFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAP 462
+ ++ P P P A S + ++ P +K KK +
Sbjct: 2268 DMASSIIESVVPKPEGPVAD-----TVSTDLLISEKDPVKKAKK------------ETGN 2310
Query: 463 GIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVP 522
GI V + + KK ++ E +S S+ V HPP+ + A+P
Sbjct: 2311 GIILEVLEAYRDKK--------------ELEAERTKSSLSETVFDHPPSSV-----IALP 2351
Query: 523 LPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAE 582
+ + S F + P +Q + S SP + P P + +
Sbjct: 2352 MKEQLSTTYFTSGETFGQEKPASQ-LPSGSPSVSSLPAKPRPFFRSSS--------LDIS 2402
Query: 583 FGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESS---------GAVTVL 633
P PP P P LP P SP T PK+ +S AVT L
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTL 2462
Query: 634 STTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEFPT 692
TT G P P + S L + P S K + PT
Sbjct: 2463 ETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPT 2521
Score = 32.3 bits (72), Expect = 3.9
Identities = 70/290 (24%), Positives = 106/290 (36%), Gaps = 48/290 (16%)
Query: 167 PRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAK--EKNISLQTAIA 224
P P P PP P P P +S P I P++ L ++ + + +L+T
Sbjct: 2408 PPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAV 2467
Query: 225 IEA----LTQLSSALPQPSHSTPQASCP-------LPEALSPPA---------------- 257
+ + +T++ + P P P +S P PE PP
Sbjct: 2468 LRSNGLPVTRICTTAPPPVPPKP-SSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKP 2526
Query: 258 ----PFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFP---PATPR--TEFPEAWGTDTPP 308
P + S + + +V ++ +P S P ++PR E + T P
Sbjct: 2527 TDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLP 2586
Query: 309 ATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAP-SSSPAPA 367
+ P + P S A LGS S + SV P P VE P SS
Sbjct: 2587 SEPGT----PTDSSASQAITSWPLGSPSKDLVSV--EPVFSVVPPVTAVEIPISSEQTFY 2640
Query: 368 PSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPS 417
S LQ + TP + P + Q A T++ Q L + S +V T APS
Sbjct: 2641 ISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVS--KTEVSATRSTAPS 2688
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 67.8 bits (164), Expect = 8e-11
Identities = 139/555 (25%), Positives = 193/555 (34%), Gaps = 101/555 (18%)
Query: 168 RLPGPLPPGEAGLPAPSTRPLLSSE--VPQISPQE-GLPLSQSALSIAKEKNISLQTAIA 224
R P P P + GL T SE +P SP L S+S + +E S+
Sbjct: 98 RPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFL 157
Query: 225 IE--ALTQLSSALP-------------------------QPSHSTPQASCPLPEALSPPA 257
E AL+ +SS + Q P+ P PP
Sbjct: 158 SEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPK 217
Query: 258 PFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPM 317
P Q R P P+ SS P+ P P T P T TP T + P+
Sbjct: 218 PIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQP--PGTGKPIQGPTQTPQ-TDHAKLPL 274
Query: 318 PRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAP 377
R + P + +D ++ +P +LP+ K ++ P+ PA P ++ P
Sbjct: 275 QRDASRPQTK-------QADIVRGESVKP-SLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326
Query: 378 TPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPP-------PSS 430
P+ P L Q + Q T+ P P++P P P PSS
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPV--QPPGTTKP-PAQPLGPAKPPAQQTGSEKPSS 383
Query: 431 --PVPRLPDRPPKEKKK--KLPTPAGGP---VGTEKAA---PGIKPSVRKP----IQIKK 476
P P+ +PP K + P PA P VGT K PG++ + P +++
Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ 443
Query: 477 SRPRE--AQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAP 534
P + AQ P G P SQ P P P G A P P +P A P
Sbjct: 444 PGPGKIPAQQAGPGKTSAQQTGPTKPPSQ--LPGPAKPPPQQPGPAKPPPQQPGSAK-PP 500
Query: 535 SPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAEFGDSFGLPGPPS 594
S S PP Q+ P+ + QPGST PP+ PG
Sbjct: 501 SQQPGSTKPPPQQ-PGPAKPSPQQPGST--KPPSQQ-------------------PGSAK 538
Query: 595 VPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAVTVLSTTCFHSEEGGQEATPTKAEN 654
P QQ P+P P A +S K + SG T +++ + P K
Sbjct: 539 -----PSAQQ---PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP-KTIC 589
Query: 655 PLTPTLSGFLESPLK 669
PL T L P K
Sbjct: 590 PLCNTTELLLHVPEK 604
Score = 56.6 bits (135), Expect = 2e-07
Identities = 133/578 (23%), Positives = 196/578 (33%), Gaps = 121/578 (20%)
Query: 142 PECPDYLEWLEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAP-STRPLLSSEVPQISPQE 200
P + EWL + GG+ P P P + AP +T +S PQ PQ+
Sbjct: 627 PHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT---APVTTTSAVSKSSPQ--PQQ 681
Query: 201 GLPLSQSA----LSIAKEKNISLQTAIAIEALTQLSSALPQPS-HSTPQASCPLP---EA 252
P +A LS A E + + QP+ H +P A P ++
Sbjct: 682 TSPKKDAAPKQDLSKAPEPK-------------KPPPLVKQPTLHGSPSAKAKQPPEADS 728
Query: 253 LSPPAPFRSPQSYLRAPSWPVVP--PEEHSSFAP--DSSAFPPATPRTEFP------EAW 302
LS PAP + P PV P++ P D + AT + + P +A
Sbjct: 729 LSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE 788
Query: 303 GTDTPP-----ATPRSSWP-------------MPRPSPD------PMAELEQLLGSASDY 338
TPP A P S+P +PRP+ D P E D
Sbjct: 789 EKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDP 848
Query: 339 IQSVFKRPEALPTKPKVKVEA---PSSSPAP-APSPVLQREAPTPSSEP----------- 383
+Q + P+ TK K +A P SP P P P + PTP P
Sbjct: 849 VQKK-EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSL 907
Query: 384 ------DTHQKAQTALQQHLHHK-----RSLFLEQ---VHDTSFPAPSEPSAPGWWPPPS 429
D + T Q+ + K S+F + + P P S PG P
Sbjct: 908 NLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG-APMKQ 966
Query: 430 SPVPRLP---DRPPKEKKKKLPTPAGG-PVGTEKAAPGIKPSVRKPIQIKKSRPREAQPL 485
+P P P PPK + P PA PV E AP + K Q + E +
Sbjct: 967 APAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKK 1026
Query: 486 FPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPT 545
PP++ S+ + A P + ++ P PE + L + S PP
Sbjct: 1027 PPPIKD----------SKSLTAEPQKAVLPTKLEKSP-KPESTCPLCKTELNIGSKDPPN 1075
Query: 546 QEMRSPSPMTALQPGSTGPLPPADDKLEELI------RQFEAEFGDSFGLPGPPSVPIQD 599
+ P P + E L R + GD +P PS P
Sbjct: 1076 FNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKAS 1135
Query: 600 P-------ENQQTCLPAPESPFATRSPKQIKIESSGAV 630
P +Q+T +P P+ + +++K E+ +
Sbjct: 1136 PMPVPTESSSQKTAVP-PQVKLVKKQEQEVKTEAEKVI 1172
Score = 48.9 bits (115), Expect = 4e-05
Identities = 111/570 (19%), Positives = 174/570 (30%), Gaps = 130/570 (22%)
Query: 159 VMEGGEERPRLPGPL-PPGEAGLPAPSTRPLLSSEVPQISPQE------GL--PLSQSAL 209
++ G +P LP P PP + P E Q P + GL PL+Q
Sbjct: 288 IVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPG 347
Query: 210 SIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPLPEALSPPAPFRSPQSYLRAP 269
++ T + L Q P + P P+AL+ P P
Sbjct: 348 TVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP------------P 395
Query: 270 SWPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPR-SSWPMPRPSPDPMAEL 328
P ++ P + P + P G +P P + P+ +P P +
Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQP---GLQSPAKAPGPTKTPVQQPGPGKIPAQ 452
Query: 329 EQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQK 388
+ G S + PTKP ++ P+ P P P S++P + Q
Sbjct: 453 QAGPGKTS--------AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504
Query: 389 AQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLP--DRPPKEKKKK 446
T P P +P P+ P P+ P +PP ++
Sbjct: 505 GSTK---------------------PPPQQPG-------PAKPSPQQPGSTKPPSQQPGS 536
Query: 447 LPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPA----- 501
A P A P + S + Q +P + + P +Q +GL
Sbjct: 537 AKPSAQQP---SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCN 593
Query: 502 SQEVQAHPPA---------------------PLP-----------------ASQGSAVPL 523
+ E+ H P P P A G P+
Sbjct: 594 TTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPV 653
Query: 524 P--PEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQ--- 578
P P+P L AP + ++ + + + SP P P K L++Q
Sbjct: 654 PSSPQPKLKT-APVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712
Query: 579 --------FEAEFGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESSGAV 630
+ DS P PP P E ++P A PKQ K+
Sbjct: 713 HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQD-------KAPVADDKPKQPKMVKPTTD 765
Query: 631 TVLSTTCFHSEEGGQEATPTKAENPLTPTL 660
V S++ + ++AE TP L
Sbjct: 766 LVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795
Score = 43.5 bits (101), Expect = 0.002
Identities = 80/353 (22%), Positives = 130/353 (36%), Gaps = 63/353 (17%)
Query: 219 LQTAIAIEALTQLSSALPQPSHSTPQASCP-LPEALSP------PAPFRSPQSYLRAPSW 271
+Q IA E+L S + + S P + P L ++S +P + S +
Sbjct: 2153 IQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTE 2212
Query: 272 PV--VPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELE 329
PV + E S S+ FP + ++PE P PD A +
Sbjct: 2213 PVDMITKFEDSEEISSSTYFPGSI--IDYPEEISVSLDRTAP----------PDGRASAD 2260
Query: 330 QLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKA 389
++ S SD S+ E++ KP+ V S+ ++ + P ++ +T
Sbjct: 2261 HIVISLSDMASSII---ESVVPKPEGPVADTVSTDL-----LISEKDPVKKAKKETGNGI 2312
Query: 390 QTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPT 449
+ + K+ L E+ S S + PPSS + P KE+
Sbjct: 2313 ILEVLEAYRDKKELEAERTK-------SSLSETVFDHPPSSVIAL----PMKEQLSTTYF 2361
Query: 450 PAGGPVGTEKAA---PGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQ 506
+G G EK A P PSV S P + +P F +S ++
Sbjct: 2362 TSGETFGQEKPASQLPSGSPSV-------SSLPAKPRPFF------------RSSSLDIS 2402
Query: 507 AHPPAPLPASQGSAVPLPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQP 559
A PP P P P PP P L P+ + ++L P +++ SP+T P
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTIL-PKKKLTVASPVTTATP 2454
Score = 40.8 bits (94), Expect = 0.011
Identities = 56/204 (27%), Positives = 67/204 (32%), Gaps = 36/204 (17%)
Query: 426 PPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQPL 485
PPP P P P PP LP P P T P K +V P+ A PL
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPPLPPPTS-PKPT--ILPKKKLTVASPVTT-------ATPL 2455
Query: 486 FPPVRQI----VLEGLRSPASQEVQAHPPA--PLPASQGSAVPLP--PEPSLALFAPSPS 537
F V + VL P ++ PP P P+S S + PEPS AP P
Sbjct: 2456 FDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPV 2515
Query: 538 RDSLLPPTQEMRSPSPM-TALQ-----------------PGSTGPLPPADDKLEELIRQF 579
L TQ+ P T L P T PL P +K +
Sbjct: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
Query: 580 EAEFGDSFGLPGPPSVPIQDPENQ 603
E LP P P +Q
Sbjct: 2576 LTETYVVITLPSEPGTPTDSSASQ 2599
Score = 37.4 bits (85), Expect = 0.12
Identities = 37/136 (27%), Positives = 65/136 (47%), Gaps = 13/136 (9%)
Query: 959 TKEDNRCVGKIPEDEQLHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLP 1018
T+ + + K+ E + +P M TD+ EE++ K + A+Q P E + +P
Sbjct: 1166 TEAEKVILEKVKETLSMEKIP--PMVTTDQ-KQEESKLEKDKASALQEKKPLPEEKKLIP 1222
Query: 1019 EPAKSCRQRQ---LEARKAAAEKKKIQKE-KLSTPEKIKQEALELAGITSDPGLSLKGGL 1074
E K + + LE +K E KK+ E K S PE+ K + L+ ++ L+G +
Sbjct: 1223 EEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEE--KLEGRV 1280
Query: 1075 S----QQGLKPSLKVE 1086
+ Q+G +P K+E
Sbjct: 1281 APKTVQEGKQPQTKME 1296
Score = 37.4 bits (85), Expect = 0.12
Identities = 62/253 (24%), Positives = 84/253 (33%), Gaps = 25/253 (9%)
Query: 180 LPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPS 239
L A T+ LS V P S +++ ++ +S + E Q A PS
Sbjct: 2326 LEAERTKSSLSETVFDHPPS-------SVIALPMKEQLSTTYFTSGETFGQEKPASQLPS 2378
Query: 240 HSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPRTEFP 299
S +S P + P PF S + P PP P PP P P
Sbjct: 2379 GSPSVSSLP-----AKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433
Query: 300 EAWGTDTPPATPRSSWPMPRPSPDPMAELEQ---LLGSASDYIQSVFKRPEALPTKPK-- 354
+ T S P D + LE L + + P +P KP
Sbjct: 2434 KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI 2493
Query: 355 ----VKVEAPSSSPAP-APSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVH 409
V P S P AP PV+ + T D H K T L L +L L
Sbjct: 2494 PSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPK-PTGLS--LTSSMTLNLVTSA 2550
Query: 410 DTSFPAPSEPSAP 422
D P+P+ P +P
Sbjct: 2551 DYKLPSPTSPLSP 2563
Score = 33.9 bits (76), Expect = 1.4
Identities = 93/419 (22%), Positives = 132/419 (31%), Gaps = 83/419 (19%)
Query: 291 PATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALP 350
P+ T P + DTP T S S P+ L D I +V+ P +
Sbjct: 2169 PSESATSVPPS---DTPSLTSSVSSVCTTDSSSPITTL--------DSITTVYTEPVDMI 2217
Query: 351 TKPKVKVEAPSSSPAPAP--------SPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRS 402
TK + E SS+ P S L R AP PD A H+ S
Sbjct: 2218 TKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAP-----PDGRASAD-----HIVISLS 2267
Query: 403 LFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAP 462
+ ++ P P P A S + ++ P +K KK +
Sbjct: 2268 DMASSIIESVVPKPEGPVAD-----TVSTDLLISEKDPVKKAKK------------ETGN 2310
Query: 463 GIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPASQGSAVP 522
GI V + + KK ++ E +S S+ V HPP+ + A+P
Sbjct: 2311 GIILEVLEAYRDKK--------------ELEAERTKSSLSETVFDHPPSSV-----IALP 2351
Query: 523 LPPEPSLALFAPSPSRDSLLPPTQEMRSPSPMTALQPGSTGPLPPADDKLEELIRQFEAE 582
+ + S F + P +Q + S SP + P P + +
Sbjct: 2352 MKEQLSTTYFTSGETFGQEKPASQ-LPSGSPSVSSLPAKPRPFFRSSS--------LDIS 2402
Query: 583 FGDSFGLPGPPSVPIQDPENQQTCLPAPESPFATRSPKQIKIESS---------GAVTVL 633
P PP P P LP P SP T PK+ +S AVT L
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTL 2462
Query: 634 STTCFHSEEGGQEATPTKAENPLTPTLSGFLESPLKYLDTPTKSLLDTPAKRAQAEFPT 692
TT G P P + S L + P S K + PT
Sbjct: 2463 ETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPT 2521
Score = 32.3 bits (72), Expect = 3.9
Identities = 70/290 (24%), Positives = 106/290 (36%), Gaps = 48/290 (16%)
Query: 167 PRLPGPLPPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSALSIAK--EKNISLQTAIA 224
P P P PP P P P +S P I P++ L ++ + + +L+T
Sbjct: 2408 PPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAV 2467
Query: 225 IEA----LTQLSSALPQPSHSTPQASCP-------LPEALSPPA---------------- 257
+ + +T++ + P P P +S P PE PP
Sbjct: 2468 LRSNGLPVTRICTTAPPPVPPKP-SSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKP 2526
Query: 258 ----PFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFP---PATPR--TEFPEAWGTDTPP 308
P + S + + +V ++ +P S P ++PR E + T P
Sbjct: 2527 TDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLP 2586
Query: 309 ATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAP-SSSPAPA 367
+ P + P S A LGS S + SV P P VE P SS
Sbjct: 2587 SEPGT----PTDSSASQAITSWPLGSPSKDLVSV--EPVFSVVPPVTAVEIPISSEQTFY 2640
Query: 368 PSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPS 417
S LQ + TP + P + Q A T++ Q L + S +V T APS
Sbjct: 2641 ISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVS--KTEVSATRSTAPS 2688
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 67.0 bits (162), Expect = 1e-10
Identities = 122/534 (22%), Positives = 183/534 (34%), Gaps = 69/534 (12%)
Query: 194 PQISPQEGLP----LSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQASCPL 249
P ++P G LS + + + + + ++A +L S QP+ + P A+ L
Sbjct: 528 PVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS----QPAPAGPAATTVL 583
Query: 250 PEALSPP---APFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAFPPATPRTEFPEAWGTDT 306
PP A +P ++ P+ P E + A P A P P G
Sbjct: 584 QGVTLPPSAVAMLNTPDGLVQ-PATPAAATGEAAPVLTVQPA-PQAPPAVSTPLPLGLQQ 641
Query: 307 PPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAP 366
P A P P+ + P A Q P + K+ + P P+
Sbjct: 642 PQAQQPPQAPTPQAAAPPQATTPQ-------------PSPGLASSPEKIVLGQP---PSA 685
Query: 367 APSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWP 426
P+ +L +++ + Q+ +A HL S+ + PAP+ P A G
Sbjct: 686 TPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGL 745
Query: 427 PPSSPVPRLPDRP----PKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREA 482
P +P + P P K P P+ P +A G P + P +RP
Sbjct: 746 GPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSP---HPTRP--- 799
Query: 483 QPLFPPVRQIVLEGLRSPASQEVQAHPPAPLPAS-------QGSAVPLPPEPSLALFAPS 535
P PP R + R P+ + PP P + Q PP + A AP
Sbjct: 800 -PSRPPSRPQSVS--RPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPG 856
Query: 536 PSRDSLLPPTQEMRSP-SPMTALQPGSTGPLPPADDKLEELI-----RQFEAEFGDSFG- 588
P + L P +Q P P L P ST + + + F+ +F S G
Sbjct: 857 PPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGP 916
Query: 589 --LPGPPSVPIQDPENQQTCLPAPE------SPFATRSPKQIKIESSGAVTVLSTTCFHS 640
P PP PE P P +PF + +E V S +
Sbjct: 917 HKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVP--SGIILQN 974
Query: 641 EEGGQEATPTKAEN--PLTPTLSGFLESPLKYLDTPT-KSLLDTPAKRAQAEFP 691
+ GG A P + + PLT + L S TPT S PA A P
Sbjct: 975 KAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLP 1028
Score = 66.6 bits (161), Expect = 2e-10
Identities = 110/444 (24%), Positives = 157/444 (35%), Gaps = 101/444 (22%)
Query: 167 PRLPGPLPPGEAGLPAPSTRPLLSSEVPQIS--PQEGLPLSQSALSIAKEKNISLQ---- 220
P + PLP GL P + + PQ + PQ P L+ + EK + Q
Sbjct: 629 PAVSTPLP---LGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSA 685
Query: 221 TAIAIEALTQLSSALPQP------SHSTPQASCPLPEALSPPAPFRSPQSYLRAPSWPVV 274
T AI L LPQ S P S P +S P P + P AP+ PV
Sbjct: 686 TPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDP-----APATPVA 740
Query: 275 PPEEHSSFAPDSSAFP---PATPRTEFPEAWGTDTPPATPRSS-------WPMP---RPS 321
APDS A P P P + G + P+ P + P P RP
Sbjct: 741 KGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPP 800
Query: 322 PDPMAELEQLLGSASDYIQSVFKRPEALPTKP-------KVKVEAPSSSPAPA----PSP 370
P + + + S+ P+A PT P ++ V P+S+PAP P P
Sbjct: 801 SRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQP 860
Query: 371 VLQREAPTP---------------------SSEPDTHQKAQTALQQHLHHKRSLFLEQVH 409
L+ ++ P SSE + A T L S + H
Sbjct: 861 PLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPS---QGPH 917
Query: 410 DTSFPAPS-----EPSAPGWWPPP-------SSPVPRLPDRPPKEKKKKLPTPAG----G 453
+ P P+ EP+AP PPP ++P P LP +P ++ P+G
Sbjct: 918 KSPTPPPTLHLVPEPAAPP--PPPPRTFQMVTTPFPALP-QPKALLERFHQVPSGIILQN 974
Query: 454 PVGTEKAAPGIKPSVRKPIQIKKSRPREAQPLFPPVRQIVLEGLRSPASQEVQAHPPAPL 513
G AAP S+ PL P +++ G + +H PAP
Sbjct: 975 KAGGAPAAPQTSTSLG--------------PLTSPAASVLVSGQAPSGTPTAPSHAPAPA 1020
Query: 514 PASQGSAVPLPPEPSLALFAPSPS 537
P + PL P + A + P+
Sbjct: 1021 PMAATGLPPLLPAENKAFASNLPT 1044
Score = 45.8 bits (107), Expect = 3e-04
Identities = 70/316 (22%), Positives = 110/316 (34%), Gaps = 44/316 (13%)
Query: 126 ALARHGMKPPNCNCDGPECPDYLEWLEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAPST 185
+++R +PP C P+ P L + V+ P P P G P P
Sbjct: 809 SVSRPPSEPPLHPCPPPQAPPTLPGI-----FVIQNQLGVPPPASNPAPTAP-GPPQPPL 862
Query: 186 RPLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQA 245
RP + P LP S ++ ++A S + + QL Q H +P
Sbjct: 863 RPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTP 922
Query: 246 SCPL---PEALSPPAPFRSPQSYLRAPSWPVVPPEE----------HSSFAPDSSAFPPA 292
L PE +PP P + P +P +P + + + PA
Sbjct: 923 PPTLHLVPEPAAPPPPPPRTFQMVTTP-FPALPQPKALLERFHQVPSGIILQNKAGGAPA 981
Query: 293 TPRTEFPEAWGTDTPPA------------TPRSSWPMPRPSPDPMAELEQLLGSASDYIQ 340
P+T + G T PA TP + P P+P L LL + +
Sbjct: 982 APQTS--TSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFA 1039
Query: 341 SVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTA-LQQHLHH 399
S P + V +SS PS + + +P T Q ++ A +HLH
Sbjct: 1040 S---------NLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHK 1090
Query: 400 KRSLFLEQVHDTSFPA 415
+ L + T+FP+
Sbjct: 1091 HQGSVLHPDYKTAFPS 1106
Score = 32.3 bits (72), Expect = 3.9
Identities = 66/287 (22%), Positives = 102/287 (35%), Gaps = 42/287 (14%)
Query: 187 PLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIE----------ALTQLSSALP 236
P+ +S P G PLS SA + + L T + I + SS+L
Sbjct: 1211 PIAASSEGHRLPGHG-PLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLS 1269
Query: 237 QPSHSTPQASC-------PLPEALSPPAPFRSPQSYLRAPSWPVVPPEEHSSFAPDSSAF 289
S S+ AS P+P PP ++ ++ R + E S ++A
Sbjct: 1270 SSSSSSSAASSLDADEDGPMPSRNRPP--IKTYEARSRIGLKLKIKQEAGLSKVVHNTAL 1327
Query: 290 PPATPRTEFPEAWGTDTPPATPRSSWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEAL 349
P PPAT + + P PRP P P Q+ G+ D+ + L
Sbjct: 1328 DPVHQ---------PPPPPATLKVAEPPPRPPPPP-PPTGQMNGTV-DHPPPAAPERKPL 1376
Query: 350 PTKP--------KVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKR 401
T P K E AP +P + +P+ P +A + L + L
Sbjct: 1377 GTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVE 1436
Query: 402 SLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEKKKKLP 448
+++ P P+ +A G P P LP P K +K + P
Sbjct: 1437 DELYQRMLKGPPPEPAASAAQG-TGDPDWEAPGLP--PAKRRKSESP 1480
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.131 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,498,143
Number of Sequences: 37866
Number of extensions: 5226647
Number of successful extensions: 35569
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 1578
Number of HSP's that attempted gapping in prelim test: 21463
Number of HSP's gapped (non-prelim): 9740
length of query: 1660
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1544
effective length of database: 13,855,062
effective search space: 21392215728
effective search space used: 21392215728
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.