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Search of human proteins with 148762980
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148762980 sialic acid binding Ig-like lectin 14 [Homo
sapiens]
(396 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148762980 sialic acid binding Ig-like lectin 14 [Homo sapiens] 814 0.0
gi|4502659 sialic acid binding Ig-like lectin 5 [Homo sapiens] 570 e-163
gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens] 355 5e-98
gi|23943856 sialic acid binding Ig-like lectin 9 [Homo sapiens] 344 9e-95
gi|7657570 sialic acid binding Ig-like lectin 7 isoform 1 [Homo ... 339 2e-93
gi|193794817 sialic acid binding Ig-like lectin 6 isoform 3 prec... 335 4e-92
gi|16506826 sialic acid binding immunoglobulin-like lectin-like ... 333 1e-91
gi|193794821 sialic acid binding Ig-like lectin 6 isoform 1 prec... 333 2e-91
gi|16506828 sialic acid binding immunoglobulin-like lectin-like ... 332 5e-91
gi|193794819 sialic acid binding Ig-like lectin 6 isoform 2 prec... 305 4e-83
gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Ho... 273 2e-73
gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1 [Ho... 273 2e-73
gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens] 273 3e-73
gi|130979981 CD33 antigen isoform 1 precursor [Homo sapiens] 268 6e-72
gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Hom... 154 2e-37
gi|130980072 CD33 antigen isoform 2 precursor [Homo sapiens] 116 4e-26
gi|11225258 myelin associated glycoprotein isoform a precursor [... 110 3e-24
gi|18104957 myelin associated glycoprotein isoform b precursor [... 110 3e-24
gi|157168355 CD22 molecule [Homo sapiens] 91 1e-18
gi|13489095 sialoadhesin precursor [Homo sapiens] 87 3e-17
gi|21686977 cell adhesion molecule 4 [Homo sapiens] 64 3e-10
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 62 1e-09
gi|47106069 sialic acid binding Ig-like lectin 15 [Homo sapiens] 61 2e-09
gi|18201909 vascular cell adhesion molecule 1 isoform b precurso... 58 1e-08
gi|4507875 vascular cell adhesion molecule 1 isoform a precursor... 58 1e-08
gi|110349719 titin isoform N2-A [Homo sapiens] 57 2e-08
gi|110349717 titin isoform novex-2 [Homo sapiens] 57 2e-08
gi|110349713 titin isoform novex-1 [Homo sapiens] 57 2e-08
gi|110349715 titin isoform N2-B [Homo sapiens] 57 2e-08
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 55 8e-08
>gi|148762980 sialic acid binding Ig-like lectin 14 [Homo sapiens]
Length = 396
Score = 814 bits (2102), Expect = 0.0
Identities = 396/396 (100%), Positives = 396/396 (100%)
Query: 1 MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW 60
MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW
Sbjct: 1 MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW 60
Query: 61 FRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRV 120
FRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRV
Sbjct: 61 FRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRV 120
Query: 121 ERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSW 180
ERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSW
Sbjct: 121 ERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSW 180
Query: 181 TGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLA 240
TGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLA
Sbjct: 181 TGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLA 240
Query: 241 ISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSM 300
ISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSM
Sbjct: 241 ISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSM 300
Query: 301 SGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSSSCICVTEKQQGSWPLVLTL 360
SGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSSSCICVTEKQQGSWPLVLTL
Sbjct: 301 SGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSSSCICVTEKQQGSWPLVLTL 360
Query: 361 IRGALMGAGFLLTYGLTWIYYTRCGGPQQSRAERPG 396
IRGALMGAGFLLTYGLTWIYYTRCGGPQQSRAERPG
Sbjct: 361 IRGALMGAGFLLTYGLTWIYYTRCGGPQQSRAERPG 396
>gi|4502659 sialic acid binding Ig-like lectin 5 [Homo sapiens]
Length = 551
Score = 570 bits (1470), Expect = e-163
Identities = 284/336 (84%), Positives = 295/336 (87%), Gaps = 5/336 (1%)
Query: 1 MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW 60
MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW
Sbjct: 1 MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW 60
Query: 61 FRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRV 120
FRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRV
Sbjct: 61 FRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRV 120
Query: 121 ERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSW 180
ERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSW
Sbjct: 121 ERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSW 180
Query: 181 TGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLA 240
TGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQ+KRQGAQVTTERTVQLNVSYAPQ +
Sbjct: 181 TGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQMKRQGAQVTTERTVQLNVSYAPQTIT 240
Query: 241 ISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSM 300
I FRN G AL IL N +P+ EGQ+L L C SNPPA LSWF+ ALN + S
Sbjct: 241 I---FRN--GIALEILQNTSYLPVLEGQALRLLCDAPSNPPAHLSWFQGSPALNATPISN 295
Query: 301 SGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSV 336
+G LEL + + E G FTCR QHPLG + LSV
Sbjct: 296 TGILELRRVRSAEEGGFTCRAQHPLGFLQIFLNLSV 331
>gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens]
Length = 499
Score = 355 bits (910), Expect = 5e-98
Identities = 191/352 (54%), Positives = 233/352 (66%), Gaps = 14/352 (3%)
Query: 1 MLPLLLLPLLWG-----GSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPP 55
+L LLLLPLLWG G Q Y LQVQ+ VTVQEGLCV VPCSFSYP W S P
Sbjct: 2 LLLLLLLPLLWGTKGMEGDRQYGDGYLLQVQELVTVQEGLCVHVPCSFSYPQDGWTDSDP 61
Query: 56 LYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGS 115
++ YWFR G+ PY VATNNPDR V+ ETQGRF+LLGD+ +CSLSI DAR D GS
Sbjct: 62 VHGYWFRAGDRPYQDAPVATNNPDREVQAETQGRFQLLGDIWSNDCSLSIRDARKRDKGS 121
Query: 116 YFFRVERGRDVKYSYQQ------NKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGS 169
YFFR+ERG +K+SY+ +L++ VTAL +PDI L LESG L+CS+P +
Sbjct: 122 YFFRLERG-SMKWSYKSQLNYKTKQLSVFVTALTHRPDILILGTLESGHSRNLTCSVPWA 180
Query: 170 CEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQ 229
C+ G P SW G ++S P T RSS LTLTP+P+DHGT+LTCQV G VTT TV+
Sbjct: 181 CKQGTPPMISWIGASVSSPGPTTARSSVLTLTPKPQDHGTSLTCQVTLPGTGVTTTSTVR 240
Query: 230 LNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFRE 289
L+VSY P NL +++F G TA L NG S+ + EGQSL L C V+SNPPA LSW R
Sbjct: 241 LDVSYPPWNLTMTVF--QGDATASTALGNGSSLSVLEGQSLRLVCAVNSNPPARLSWTRG 298
Query: 290 GKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSS 341
L PS++S G LELP + R+ GEFTCR Q+ GSQH+S LS+Q +
Sbjct: 299 SLTLCPSRSSNPGLLELPRVHVRDEGEFTCRAQNAQGSQHISLSLSLQNEGT 350
>gi|23943856 sialic acid binding Ig-like lectin 9 [Homo sapiens]
Length = 463
Score = 344 bits (882), Expect = 9e-95
Identities = 186/344 (54%), Positives = 228/344 (66%), Gaps = 8/344 (2%)
Query: 4 LLLLPLLWGGSLQEKPVYEL-QVQKSVTVQEGLCVLVPCSFSYPWRSW-YSSPPLYVYWF 61
LLLLPLLWG E +L +Q SVTVQEGLCV VPCSFSYP W Y P ++ YWF
Sbjct: 3 LLLLPLLWGRERAEGQTSKLLTMQSSVTVQEGLCVHVPCSFSYPSHGWIYPGPVVHGYWF 62
Query: 62 RDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVE 121
R+G VATNNP R V ET+ RF LLGD KNC+LSI DAR D G YFFR+E
Sbjct: 63 REGANTDQDAPVATNNPARAVWEETRDRFHLLGDPHTKNCTLSIRDARRSDAGRYFFRME 122
Query: 122 RGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWT 181
+G +K++Y+ ++L++ VTAL +P+I LESG P L+CS+P +CE G P SW
Sbjct: 123 KG-SIKWNYKHHRLSVNVTALTHRPNILIPGTLESGCPQNLTCSVPWACEQGTPPMISWI 181
Query: 182 GNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAI 241
G ++SPLDP TTRSS LTL P+P+DHGT+LTCQV GA VTT +TV LNVSY PQNL +
Sbjct: 182 GTSVSPLDPSTTRSSVLTLIPQPQDHGTSLTCQVTFPGASVTTNKTVHLNVSYPPQNLTM 241
Query: 242 SIFFRNGTGTALRILSNGMSVPIQEGQSLFLAC---TVDSNPPASLSWFREGKALNPSQT 298
++F G GT +L NG S+ + EGQSL L C VDSNPPA LS G L PSQ
Sbjct: 242 TVF--QGDGTVSTVLGNGSSLSLPEGQSLRLVCAVDAVDSNPPARLSLSWRGLTLCPSQP 299
Query: 299 SMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSSS 342
S G LELP + R+ EFTCR Q+PLGSQ + +S+Q ++S
Sbjct: 300 SNPGVLELPWVHLRDAAEFTCRAQNPLGSQQVYLNVSLQSKATS 343
>gi|7657570 sialic acid binding Ig-like lectin 7 isoform 1 [Homo
sapiens]
Length = 467
Score = 339 bits (870), Expect = 2e-93
Identities = 192/374 (51%), Positives = 238/374 (63%), Gaps = 19/374 (5%)
Query: 1 MLPLLLLPLLWG-----GSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPP 55
ML LLLLPLLWG G + Y L +Q SVTVQEG+CV V CSFSYP S S P
Sbjct: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60
Query: 56 LYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGS 115
++ YWFR G + VATNNP V+ ET+ RF LLGD Q KNC+LSI DARM D G
Sbjct: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120
Query: 116 YFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPP 175
YFFR+E+G ++K++Y+ ++L++ VTAL +P+I LESG L+CS+P +CE G P
Sbjct: 121 YFFRMEKG-NIKWNYKYDQLSVNVTALTHRPNILIPGTLESGCFQNLTCSVPWACEQGTP 179
Query: 176 LTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYA 235
SW G ++SPL P TTRSS LTL P+P+ HGT+LTCQV GA VTT RT+QLNVSY
Sbjct: 180 PMISWMGTSVSPLHPSTTRSSVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVSYP 239
Query: 236 PQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNP 295
PQNL +++F G GTA L N S+ + EGQSL L C VDSNPPA LSW L P
Sbjct: 240 PQNLTVTVF--QGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYP 297
Query: 296 SQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSSSCICVTEKQQGSWP 355
SQ S LEL + + GEFTCR Q+ LGSQH+S LS+Q ++ G
Sbjct: 298 SQPSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSLQ----------QEYTGKMR 346
Query: 356 LVLTLIRGALMGAG 369
V ++ GA+ GAG
Sbjct: 347 PVSGVLLGAVGGAG 360
>gi|193794817 sialic acid binding Ig-like lectin 6 isoform 3
precursor [Homo sapiens]
Length = 353
Score = 335 bits (859), Expect = 4e-92
Identities = 181/342 (52%), Positives = 229/342 (66%), Gaps = 13/342 (3%)
Query: 1 MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW 60
MLPLLL PLLW G+L ++ ++L+ +S+TVQEGLCVLVPC + Y Y YW
Sbjct: 12 MLPLLL-PLLWAGALAQERRFQLEGPESLTVQEGLCVLVPCRLPTTLPASYYG---YGYW 67
Query: 61 FRDG-EIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFR 119
F +G ++P VATN+PD V+ ET+GRF LL D ++KNCSLSI DAR D +YFFR
Sbjct: 68 FLEGADVP-----VATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFR 122
Query: 120 VERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFS 179
+ + + +KY Y +KL++ V AL +P+I LESG P+ L+CS+P CE G P FS
Sbjct: 123 L-KSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFS 181
Query: 180 WTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNL 239
W A + L P TT+SS LT+TPRP+DH TNLTCQV GA VT ERT+QLNVSYAPQ +
Sbjct: 182 WMSAAPTSLGPRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSYAPQKV 241
Query: 240 AISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTS 299
AISIF G A +IL N S+P+ EGQ+L L C D NPPA LSWF+ ALN + S
Sbjct: 242 AISIF--QGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPIS 299
Query: 300 MSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSS 341
+G LELP +G+ E G+FTCR QHPLGS +S L V SS+
Sbjct: 300 NTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWSSA 341
>gi|16506826 sialic acid binding immunoglobulin-like lectin-like
protein 1 isoform b precursor [Homo sapiens]
Length = 477
Score = 333 bits (855), Expect = 1e-91
Identities = 178/350 (50%), Positives = 227/350 (64%), Gaps = 21/350 (6%)
Query: 5 LLLPLLWGGSLQEK----------------PVYELQVQKSVTVQEGLCVLVPCSFSYPWR 48
+LLPLLW ++ Y L+V +SVTVQEGLCV VPCS YP
Sbjct: 1 MLLPLLWANEERDSGGWADPRFSTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHY 60
Query: 49 SWYSSPPLYVYWFRDG-EIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGD 107
+W +S P+Y WF++G +IP+ V ATN P +V+ +T GRF LLGD Q NCSLSI D
Sbjct: 61 NWTASSPVYGSWFKEGADIPWDIPV-ATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRD 119
Query: 108 ARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLP 167
AR D+G Y+F+VERG K++Y +KL++ VTAL P LESG P L+CS+P
Sbjct: 120 ARKGDSGKYYFQVERGSR-KWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVP 178
Query: 168 GSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERT 227
+CE G P T +W G ++S LDP TRSS L+L P+P+DHGT+LTCQV GA VT R
Sbjct: 179 WACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRA 238
Query: 228 VQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWF 287
V+LN+SY PQNL +++F G GTA L NG ++ + EGQSL L C VDSNPPA LSW
Sbjct: 239 VRLNISYPPQNLTMTVF--QGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWT 296
Query: 288 REGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ 337
L+PSQ+S G LELP + ++ GEFTCR Q+PLGSQH+S LS+Q
Sbjct: 297 WGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 346
>gi|193794821 sialic acid binding Ig-like lectin 6 isoform 1
precursor [Homo sapiens]
Length = 453
Score = 333 bits (853), Expect = 2e-91
Identities = 179/337 (53%), Positives = 226/337 (67%), Gaps = 13/337 (3%)
Query: 1 MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW 60
MLPLLL PLLW G+L ++ ++L+ +S+TVQEGLCVLVPC + Y Y YW
Sbjct: 12 MLPLLL-PLLWAGALAQERRFQLEGPESLTVQEGLCVLVPCRLPTTLPASYYG---YGYW 67
Query: 61 FRDG-EIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFR 119
F +G ++P VATN+PD V+ ET+GRF LL D ++KNCSLSI DAR D +YFFR
Sbjct: 68 FLEGADVP-----VATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFR 122
Query: 120 VERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFS 179
+ + + +KY Y +KL++ V AL +P+I LESG P+ L+CS+P CE G P FS
Sbjct: 123 L-KSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFS 181
Query: 180 WTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNL 239
W A + L P TT+SS LT+TPRP+DH TNLTCQV GA VT ERT+QLNVSYAPQ +
Sbjct: 182 WMSAAPTSLGPRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSYAPQKV 241
Query: 240 AISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTS 299
AISIF G A +IL N S+P+ EGQ+L L C D NPPA LSWF+ ALN + S
Sbjct: 242 AISIF--QGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPIS 299
Query: 300 MSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSV 336
+G LELP +G+ E G+FTCR QHPLGS +S L V
Sbjct: 300 NTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFV 336
>gi|16506828 sialic acid binding immunoglobulin-like lectin-like
protein 1 isoform a precursor [Homo sapiens]
Length = 595
Score = 332 bits (850), Expect = 5e-91
Identities = 172/318 (54%), Positives = 218/318 (68%), Gaps = 5/318 (1%)
Query: 21 YELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDG-EIPYYAEVVATNNPD 79
Y L+V +SVTVQEGLCV VPCS YP +W +S P+Y WF++G +IP+ V ATN P
Sbjct: 151 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPV-ATNTPS 209
Query: 80 RRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEV 139
+V+ +T GRF LLGD Q NCSLSI DAR D+G Y+F+VERG K++Y +KL++ V
Sbjct: 210 GKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSR-KWNYIYDKLSVHV 268
Query: 140 TALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELT 199
TAL P LESG P L+CS+P +CE G P T +W G ++S LDP TRSS L+
Sbjct: 269 TALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLS 328
Query: 200 LTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNG 259
L P+P+DHGT+LTCQV GA VT R V+LN+SY PQNL +++F G GTA L NG
Sbjct: 329 LIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVF--QGDGTASTTLRNG 386
Query: 260 MSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTC 319
++ + EGQSL L C VDSNPPA LSW L+PSQ+S G LELP + ++ GEFTC
Sbjct: 387 SALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTC 446
Query: 320 RVQHPLGSQHLSFILSVQ 337
R Q+PLGSQH+S LS+Q
Sbjct: 447 RAQNPLGSQHISLSLSLQ 464
Score = 137 bits (346), Expect = 1e-32
Identities = 80/157 (50%), Positives = 104/157 (66%), Gaps = 2/157 (1%)
Query: 1 MLPLLLLPLLWGG-SLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVY 59
+L LLL PLL G +E+ Y L +QKSVTVQEGLCV V CSFSYP W +S P++ Y
Sbjct: 3 LLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGY 62
Query: 60 WFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFR 119
WFR G+ VATNNP R V+ ET+ RF LLGD Q K+C+LSI D R D G+Y F
Sbjct: 63 WFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFC 122
Query: 120 VERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLES 156
VERG ++K++Y+ ++L++ VTA + + LE ES
Sbjct: 123 VERG-NMKWNYKYDQLSVNVTASQDLLSRYRLEVPES 158
>gi|193794819 sialic acid binding Ig-like lectin 6 isoform 2
precursor [Homo sapiens]
Length = 437
Score = 305 bits (782), Expect = 4e-83
Identities = 168/337 (49%), Positives = 215/337 (63%), Gaps = 29/337 (8%)
Query: 1 MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW 60
MLPLLL PLLW G+L ++ ++L+ +S+TVQEGLCVLVPC + Y Y YW
Sbjct: 12 MLPLLL-PLLWAGALAQERRFQLEGPESLTVQEGLCVLVPCRLPTTLPASYYG---YGYW 67
Query: 61 FRDG-EIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFR 119
F +G ++P VATN+PD V+ ET+GRF LL D ++KNCSLSI DAR D +YFFR
Sbjct: 68 FLEGADVP-----VATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFR 122
Query: 120 VERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFS 179
+ + + +KY Y +KL++ V AL +P+I LESG P+ L+CS+P CE G P FS
Sbjct: 123 L-KSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFS 181
Query: 180 WTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNL 239
W A + L P TT+SS LT+TPRP+DH TNLTCQV GA VT ERT+QLNVS
Sbjct: 182 WMSAAPTSLGPRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVS------ 235
Query: 240 AISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTS 299
+ +IL N S+P+ EGQ+L L C D NPPA LSWF+ ALN + S
Sbjct: 236 ------------SFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPIS 283
Query: 300 MSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSV 336
+G LELP +G+ E G+FTCR QHPLGS +S L V
Sbjct: 284 NTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFV 320
>gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Homo
sapiens]
Length = 602
Score = 273 bits (699), Expect = 2e-73
Identities = 156/341 (45%), Positives = 206/341 (60%), Gaps = 7/341 (2%)
Query: 1 MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW 60
+LPLLL P+L GSL + P Y LQVQ+ V V EGLCV+V C+ SYP W S Y YW
Sbjct: 15 LLPLLL-PVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYW 73
Query: 61 FRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRV 120
F+ P VATNN R V+ T+ RF+L GD K +CSL I DA+ ED YFFRV
Sbjct: 74 FKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRV 133
Query: 121 ERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSW 180
ERG V++S+ N L+VTAL +KPD++ E LE G+P + C + + P +FSW
Sbjct: 134 ERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSW 193
Query: 181 TGNALSP--LDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQN 238
TG ALSP P T+ S L+ TP P+DH T+LTC V V+ +RTV+L V+YAP++
Sbjct: 194 TGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKD 253
Query: 239 LAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQT 298
L ISI N +AL + N + + +Q+GQ L L C DS PPA+LSW + + L+ S
Sbjct: 254 LIISISHDN--TSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHP 311
Query: 299 SMSGT--LELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ 337
T LEL + A + G +TCR ++ LGSQ + LSVQ
Sbjct: 312 WGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQ 352
Score = 123 bits (309), Expect = 3e-28
Identities = 81/200 (40%), Positives = 109/200 (54%), Gaps = 13/200 (6%)
Query: 140 TALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWT--GNALSPLDPETTRSSE 197
+AL + ++ +LE ++ G+ RL C+ ++ PP T SW LS P R+
Sbjct: 264 SALELQGNVIYLE-VQKGQFLRLLCA----ADSQPPATLSWVLQDRVLSSSHPWGPRTLG 318
Query: 198 LTLTPRPEDHGTNLTCQVK-RQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRIL 256
L L TC+ + R G+Q ++ + L+V Y P+NL + + N T L L
Sbjct: 319 LELRGVRAGDSGRYTCRAENRLGSQ---QQALDLSVQYPPENLRVMVSQANRT--VLENL 373
Query: 257 SNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGE 316
NG S+P+ EGQSL L C S+PPA LSW R G+ + PSQ S G LELP I GE
Sbjct: 374 GNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGE 433
Query: 317 FTCRVQHPLGSQHLSFILSV 336
FTC QHPLGSQH+S LSV
Sbjct: 434 FTCHAQHPLGSQHVSLSLSV 453
>gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1 [Homo
sapiens]
Length = 698
Score = 273 bits (699), Expect = 2e-73
Identities = 156/341 (45%), Positives = 206/341 (60%), Gaps = 7/341 (2%)
Query: 1 MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW 60
+LPLLL P+L GSL + P Y LQVQ+ V V EGLCV+V C+ SYP W S Y YW
Sbjct: 15 LLPLLL-PVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYW 73
Query: 61 FRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRV 120
F+ P VATNN R V+ T+ RF+L GD K +CSL I DA+ ED YFFRV
Sbjct: 74 FKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRV 133
Query: 121 ERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSW 180
ERG V++S+ N L+VTAL +KPD++ E LE G+P + C + + P +FSW
Sbjct: 134 ERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSW 193
Query: 181 TGNALSP--LDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQN 238
TG ALSP P T+ S L+ TP P+DH T+LTC V V+ +RTV+L V+YAP++
Sbjct: 194 TGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKD 253
Query: 239 LAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQT 298
L ISI N +AL + N + + +Q+GQ L L C DS PPA+LSW + + L+ S
Sbjct: 254 LIISISHDN--TSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHP 311
Query: 299 SMSGT--LELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ 337
T LEL + A + G +TCR ++ LGSQ + LSVQ
Sbjct: 312 WGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQ 352
Score = 123 bits (309), Expect = 3e-28
Identities = 81/200 (40%), Positives = 109/200 (54%), Gaps = 13/200 (6%)
Query: 140 TALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWT--GNALSPLDPETTRSSE 197
+AL + ++ +LE ++ G+ RL C+ ++ PP T SW LS P R+
Sbjct: 264 SALELQGNVIYLE-VQKGQFLRLLCA----ADSQPPATLSWVLQDRVLSSSHPWGPRTLG 318
Query: 198 LTLTPRPEDHGTNLTCQVK-RQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRIL 256
L L TC+ + R G+Q ++ + L+V Y P+NL + + N T L L
Sbjct: 319 LELRGVRAGDSGRYTCRAENRLGSQ---QQALDLSVQYPPENLRVMVSQANRT--VLENL 373
Query: 257 SNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGE 316
NG S+P+ EGQSL L C S+PPA LSW R G+ + PSQ S G LELP I GE
Sbjct: 374 GNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGE 433
Query: 317 FTCRVQHPLGSQHLSFILSV 336
FTC QHPLGSQH+S LSV
Sbjct: 434 FTCHAQHPLGSQHVSLSLSV 453
Score = 40.4 bits (93), Expect = 0.003
Identities = 56/225 (24%), Positives = 82/225 (36%), Gaps = 53/225 (23%)
Query: 99 KNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVT-------ALIEKPDIHFL 151
+ L + R D+G Y R E + QQ L+L V ++ + + L
Sbjct: 315 RTLGLELRGVRAGDSGRYTCRAEN----RLGSQQQALDLSVQYPPENLRVMVSQANRTVL 370
Query: 152 E--------PLESGRPTRLSCSLPGSCEAGPPLTFSWT--GNALSPLDPETTRSSELTLT 201
E P+ G+ RL C S PP SWT G + P P L L
Sbjct: 371 ENLGNGTSLPVLEGQSLRLVCVTHSS----PPARLSWTRWGQTVGPSQPSDP--GVLELP 424
Query: 202 PRPEDHGTNLTCQVKRQ-GAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGM 260
P +H TC + G+Q + + L+V Y PQ L S +
Sbjct: 425 PIQMEHEGEFTCHAQHPLGSQHVS---LSLSVHYPPQLLGPSCSW--------------- 466
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKAL--NPSQTSMSGT 303
E + L +C+ ++P SL W+ + L N SQ S T
Sbjct: 467 -----EAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVT 506
>gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens]
Length = 697
Score = 273 bits (697), Expect = 3e-73
Identities = 155/341 (45%), Positives = 204/341 (59%), Gaps = 5/341 (1%)
Query: 1 MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW 60
+LPLLL LL GGS + ++VQ+SV V EGLC+ VPCSFSYP + W S P Y YW
Sbjct: 2 LLPLLLSSLL-GGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYW 60
Query: 61 FRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRV 120
F+ VATN+ R V+ T+GRF+L GD K NCSL I DA+M+D YFFRV
Sbjct: 61 FKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRV 120
Query: 121 ERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSW 180
ERG V+Y++ + L+VTAL +KPD++ E LE G+P + C + E PP +FSW
Sbjct: 121 ERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSW 180
Query: 181 TGNALSP--LDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQN 238
TG ALS P T+ S L+ TPRP+DH T+LTC V V+ +RTV+L V+YAP++
Sbjct: 181 TGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRD 240
Query: 239 LAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQT 298
L ISI N + N + Q+GQ L L C DS PPA+LSW + + L+ S
Sbjct: 241 LVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP 300
Query: 299 --SMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ 337
LELP + A + G +TCR ++ LGSQ + LSVQ
Sbjct: 301 WGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQ 341
Score = 125 bits (314), Expect = 7e-29
Identities = 79/196 (40%), Positives = 105/196 (53%), Gaps = 13/196 (6%)
Query: 147 DIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWT--GNALSPLDPETTRSSELTLTPRP 204
++ +LE + G+ RL C+ ++ PP T SW LS P R L L
Sbjct: 260 NVPYLEA-QKGQFLRLLCA----ADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVK 314
Query: 205 EDHGTNLTCQVK-RQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVP 263
TC+ + R G+Q +R + L+V Y P+NL + + N T L L NG S+P
Sbjct: 315 AGDSGRYTCRAENRLGSQ---QRALDLSVQYPPENLRVMVSQANRT--VLENLGNGTSLP 369
Query: 264 IQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQH 323
+ EGQSL L C S+PPA LSW + G+ L+PSQ S G LELP + GEFTC +H
Sbjct: 370 VLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARH 429
Query: 324 PLGSQHLSFILSVQRS 339
PLGSQH+S LSV S
Sbjct: 430 PLGSQHVSLSLSVHYS 445
Score = 39.3 bits (90), Expect = 0.006
Identities = 57/218 (26%), Positives = 85/218 (38%), Gaps = 47/218 (21%)
Query: 103 LSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVT-------ALIEKPDIHFLEPLE 155
L + + D+G Y R E + QQ L+L V ++ + + LE L
Sbjct: 308 LELPGVKAGDSGRYTCRAEN----RLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLG 363
Query: 156 SGR--PTRLSCSLPGSC--EAGPPLTFSWT--GNALSPLDPETTRSSELTLTPRPE-DHG 208
+G P SL C + PP SWT G LSP P EL PR + +H
Sbjct: 364 NGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLEL---PRVQVEHE 420
Query: 209 TNLTCQVKRQ-GAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEG 267
TC + G+Q + + L+V Y+P+ L S + E
Sbjct: 421 GEFTCHARHPLGSQHVS---LSLSVHYSPKLLGPSCSW--------------------EA 457
Query: 268 QSLFLACTVDSNPPASLSWFREGKAL--NPSQTSMSGT 303
+ L +C+ ++P SL W+ + L N SQ S T
Sbjct: 458 EGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVT 495
>gi|130979981 CD33 antigen isoform 1 precursor [Homo sapiens]
Length = 364
Score = 268 bits (685), Expect = 6e-72
Identities = 140/247 (56%), Positives = 169/247 (68%), Gaps = 1/247 (0%)
Query: 4 LLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRD 63
LLLLPLLW G+L P + LQVQ+SVTVQEGLCVLVPC+F +P + + P++ YWFR+
Sbjct: 4 LLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFRE 63
Query: 64 GEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERG 123
G I VATN D+ V+ ETQGRFRLLGD + NCSLSI DAR D GSYFFR+ERG
Sbjct: 64 GAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMERG 123
Query: 124 RDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGN 183
KYSY+ +L++ VT L +P I LE G L+CS+ +CE G P FSW
Sbjct: 124 -STKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSA 182
Query: 184 ALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISI 243
A + L P TT SS L +TPRP+DHGTNLTCQVK GA VTTERT+QLNV+Y PQN I
Sbjct: 183 APTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGI 242
Query: 244 FFRNGTG 250
F +G+G
Sbjct: 243 FPGDGSG 249
Score = 29.3 bits (64), Expect = 6.5
Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 7/41 (17%)
Query: 261 SVPIQEGQSLFLACTV-------DSNPPASLSWFREGKALN 294
SV +QEG + + CT D N P WFREG ++
Sbjct: 28 SVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAIIS 68
>gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Homo
sapiens]
Length = 374
Score = 154 bits (388), Expect = 2e-37
Identities = 107/285 (37%), Positives = 142/285 (49%), Gaps = 38/285 (13%)
Query: 1 MLPLLLLPLLWG-----GSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPP 55
ML LLLLPLLWG G + Y L +Q SVTVQEG+CV V CSFSYP S S P
Sbjct: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60
Query: 56 LYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGS 115
++ YWFR G + VATNNP V+ ET+ RF LLGD Q KNC+LSI DARM D G
Sbjct: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120
Query: 116 YFFRVERGRDVKYSYQQNKLNLEV-------------------TALIEKPDIHFLEPLES 156
YFFR+E+G ++K++Y+ ++L++ V TAL + LE
Sbjct: 121 YFFRMEKG-NIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLE---- 175
Query: 157 GRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVK 216
G+ RL C++ ++ PP SWT +L+ + + L L D G TC+ +
Sbjct: 176 GQSLRLVCAV----DSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEG-EFTCRAQ 230
Query: 217 RQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTG----TALRILS 257
+ L Y + +S G TAL LS
Sbjct: 231 NSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLS 275
Score = 99.4 bits (246), Expect = 5e-21
Identities = 62/142 (43%), Positives = 80/142 (56%), Gaps = 13/142 (9%)
Query: 228 VQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWF 287
+ +NV+ PQNL +++F G GTA L N S+ + EGQSL L C VDSNPPA LSW
Sbjct: 139 LSVNVTDPPQNLTVTVF--QGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWT 196
Query: 288 REGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSSSCICVT 347
L PSQ S LEL + + GEFTCR Q+ LGSQH+S LS+Q
Sbjct: 197 WRSLTLYPSQPSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSLQ---------- 245
Query: 348 EKQQGSWPLVLTLIRGALMGAG 369
++ G V ++ GA+ GAG
Sbjct: 246 QEYTGKMRPVSGVLLGAVGGAG 267
>gi|130980072 CD33 antigen isoform 2 precursor [Homo sapiens]
Length = 237
Score = 116 bits (290), Expect = 4e-26
Identities = 59/109 (54%), Positives = 70/109 (64%)
Query: 142 LIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLT 201
L +P I LE G L+CS+ +CE G P FSW A + L P TT SS L +T
Sbjct: 14 LTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIIT 73
Query: 202 PRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTG 250
PRP+DHGTNLTCQVK GA VTTERT+QLNV+Y PQN IF +G+G
Sbjct: 74 PRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSG 122
>gi|11225258 myelin associated glycoprotein isoform a precursor
[Homo sapiens]
Length = 626
Score = 110 bits (274), Expect = 3e-24
Identities = 93/348 (26%), Positives = 145/348 (41%), Gaps = 38/348 (10%)
Query: 1 MLPLLLLPLLWGG-SLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVY 59
M+ L LPL W S + + S++ EG CV +PC F +P ++
Sbjct: 1 MIFLTALPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFP--DELRPAVVHGV 58
Query: 60 WFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFR 119
W+ + P V + + V QGR RLLGD+ +NC+L + + E G Y+FR
Sbjct: 59 WYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFR 118
Query: 120 VERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSC-EAGPPLTF 178
+ G +Y++ ++ V ++ P+I + +G +SC +P +C E P L
Sbjct: 119 GDLGGYNQYTFSEH----SVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPEL-- 172
Query: 179 SWTGN----------ALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTV 228
SW G+ L + + S L P E +G L CQ + E
Sbjct: 173 SWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYA 232
Query: 229 QLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFR 288
++V Y P I+ SV EG + L C DSNPP L+W R
Sbjct: 233 SMDVKYPPV-----------------IVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMR 275
Query: 289 EGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSV 336
+G L + + S LEL + E G + C ++ G + + LSV
Sbjct: 276 DGTVLREA-VAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSV 322
Score = 52.4 bits (124), Expect = 7e-07
Identities = 50/200 (25%), Positives = 80/200 (40%), Gaps = 38/200 (19%)
Query: 165 SLPGSCEAGPPLTFSWT--GNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQV 222
SL ++ PP +W G L E+ +TP + L + A
Sbjct: 258 SLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVTPAEDGVYACLA-----ENAYG 312
Query: 223 TTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPA 282
RTV L+V YAP + NGT A+ EG+++ + C+ SNP
Sbjct: 313 QDNRTVGLSVMYAPWKPTV-----NGTMVAV------------EGETVSILCSTQSNPDP 355
Query: 283 SLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ----- 337
L+ F+E + L+ LELP + + GE+ C ++ G + +F LSV+
Sbjct: 356 ILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAPVL 415
Query: 338 ---------RSSSSCICVTE 348
R + C+CV +
Sbjct: 416 LLESHCAAARDTVQCLCVVK 435
>gi|18104957 myelin associated glycoprotein isoform b precursor
[Homo sapiens]
Length = 582
Score = 110 bits (274), Expect = 3e-24
Identities = 93/348 (26%), Positives = 145/348 (41%), Gaps = 38/348 (10%)
Query: 1 MLPLLLLPLLWGG-SLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVY 59
M+ L LPL W S + + S++ EG CV +PC F +P ++
Sbjct: 1 MIFLTALPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFP--DELRPAVVHGV 58
Query: 60 WFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFR 119
W+ + P V + + V QGR RLLGD+ +NC+L + + E G Y+FR
Sbjct: 59 WYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFR 118
Query: 120 VERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSC-EAGPPLTF 178
+ G +Y++ ++ V ++ P+I + +G +SC +P +C E P L
Sbjct: 119 GDLGGYNQYTFSEH----SVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPEL-- 172
Query: 179 SWTGN----------ALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTV 228
SW G+ L + + S L P E +G L CQ + E
Sbjct: 173 SWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYA 232
Query: 229 QLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFR 288
++V Y P I+ SV EG + L C DSNPP L+W R
Sbjct: 233 SMDVKYPPV-----------------IVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMR 275
Query: 289 EGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSV 336
+G L + + S LEL + E G + C ++ G + + LSV
Sbjct: 276 DGTVLREA-VAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSV 322
Score = 52.4 bits (124), Expect = 7e-07
Identities = 50/200 (25%), Positives = 80/200 (40%), Gaps = 38/200 (19%)
Query: 165 SLPGSCEAGPPLTFSWT--GNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQV 222
SL ++ PP +W G L E+ +TP + L + A
Sbjct: 258 SLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVTPAEDGVYACLA-----ENAYG 312
Query: 223 TTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPA 282
RTV L+V YAP + NGT A+ EG+++ + C+ SNP
Sbjct: 313 QDNRTVGLSVMYAPWKPTV-----NGTMVAV------------EGETVSILCSTQSNPDP 355
Query: 283 SLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ----- 337
L+ F+E + L+ LELP + + GE+ C ++ G + +F LSV+
Sbjct: 356 ILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAPVL 415
Query: 338 ---------RSSSSCICVTE 348
R + C+CV +
Sbjct: 416 LLESHCAAARDTVQCLCVVK 435
>gi|157168355 CD22 molecule [Homo sapiens]
Length = 847
Score = 91.3 bits (225), Expect = 1e-18
Identities = 81/336 (24%), Positives = 141/336 (41%), Gaps = 37/336 (11%)
Query: 3 PLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFR 62
P LLL +L + + + + +++ EG CV +PC++ S + +
Sbjct: 6 PWLLLLVLEYLAFSDSSKWVFEHPETLYAWEGACVWIPCTYRALDGDLESFILFHNPEYN 65
Query: 63 DGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVER 122
+ + + D +V P Q R + LGD + KNC+LSI + D+G R+E
Sbjct: 66 KNTSKFDGTRLYESTKDGKV-PSEQKRVQFLGD-KNKNCTLSIHPVHLNDSGQLGLRMES 123
Query: 123 GRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTG 182
K +++L V+ P I ++ + L+C L SC G P+ W
Sbjct: 124 ----KTEKWMERIHLNVSERPFPPHIQLPPEIQESQEVTLTCLLNFSCY-GYPIQLQWLL 178
Query: 183 NALSPLDPETTRSS----------ELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNV 232
+ T +S EL +P+ HG +TCQ++ + + TVQLNV
Sbjct: 179 EGVPMRQAAVTSTSLTIKSVFTRSELKFSPQWSHHGKIVTCQLQDADGKFLSNDTVQLNV 238
Query: 233 SYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPP--ASLSWFREG 290
+ P+ L I ++EG S+ + C V S+ P ++SW ++G
Sbjct: 239 KHTPK---------------LEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTTVSWLKDG 283
Query: 291 KALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLG 326
+L T TL L + + G++ C+V + +G
Sbjct: 284 TSLKKQNTF---TLNLREVTKDQSGKYCCQVSNDVG 316
Score = 41.2 bits (95), Expect = 0.002
Identities = 48/178 (26%), Positives = 67/178 (37%), Gaps = 29/178 (16%)
Query: 151 LEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTP-RPEDHGT 209
L + SG L C S + G L + S+L PED G+
Sbjct: 516 LSEIHSGNSVSLQCDFSSSHPKEVQFFWEKNGRLLG-------KESQLNFDSISPEDAGS 568
Query: 210 NLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQS 269
+C V Q T + L V YAP+ L +S +S G V EG+S
Sbjct: 569 -YSCWVNNSIGQ-TASKAWTLEVLYAPRRLRVS-------------MSPGDQV--MEGKS 611
Query: 270 LFLACTVDSNPPAS-LSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLG 326
L C D+NPP S +WF N S S L L + + G + C+ + +G
Sbjct: 612 ATLTCESDANPPVSHYTWFDWN---NQSLPYHSQKLRLEPVKVQHSGAYWCQGTNSVG 666
Score = 39.7 bits (91), Expect = 0.005
Identities = 63/318 (19%), Positives = 120/318 (37%), Gaps = 52/318 (16%)
Query: 14 SLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVV 73
++ E+P + +Q +QE V + C ++ + P+ + W +G A V
Sbjct: 135 NVSERP-FPPHIQLPPEIQESQEVTLTCLLNFSCYGY----PIQLQWLLEGVPMRQAAVT 189
Query: 74 ATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQN 133
+T+ + V ++ +F K + + DA G + +VK++
Sbjct: 190 STSLTIKSVFTRSELKFSPQWSHHGKIVTCQLQDA----DGKFLSNDTVQLNVKHT---P 242
Query: 134 KLNLEVT---ALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDP 190
KL ++VT A++ + D ++C + S +++ G +L +
Sbjct: 243 KLEIKVTPSDAIVREGD-----------SVTMTCEVSSSNPEYTTVSWLKDGTSLKKQNT 291
Query: 191 ETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTG 250
T E+T +D CQV +E V L V YAP+ + I
Sbjct: 292 FTLNLREVT-----KDQSGKYCCQVSNDVGPGRSEE-VFLQVQYAPEPSTVQI------- 338
Query: 251 TALRILSNGMSVPIQEGQSLFLACTVDSNP-PASLSWFREGKALNPSQTSMSGTLELPNI 309
+ P EG + C +NP P + +W+ GK + Q + +P I
Sbjct: 339 ---------LHSPAVEGSQVEFLCMSLANPLPTNYTWYHNGKEM---QGRTEEKVHIPKI 386
Query: 310 GAREGGEFTCRVQHPLGS 327
G ++C ++ LG+
Sbjct: 387 LPWHAGTYSCVAENILGT 404
>gi|13489095 sialoadhesin precursor [Homo sapiens]
Length = 1709
Score = 86.7 bits (213), Expect = 3e-17
Identities = 80/308 (25%), Positives = 132/308 (42%), Gaps = 40/308 (12%)
Query: 33 EGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRL 92
+G C+L+PC FS+P + W+ D +VV+ + + V+ +GR
Sbjct: 33 KGSCLLIPCIFSFP-ADVEVPDGITAIWYYD--YSGQRQVVSHSADPKLVEARFRGRTEF 89
Query: 93 LGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLE 152
+G+ + + C+L + D + ED+GSY FR E ++S + L + VT P I
Sbjct: 90 MGNPEHRVCNLLLKDLQPEDSGSYNFRFEISEVNRWSDVKGTL-VTVTEEPRVPTIASPV 148
Query: 153 PLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSE-----------LTLT 201
L G +CS P C + W G P T S + L +
Sbjct: 149 ELLEGTEVDFNCSTPYVC-LQEQVRLQWQGQ--DPARSVTFNSQKFEPTGVGHLETLHMA 205
Query: 202 PRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMS 261
+DHG L CQ+ + +E + L V YAP+ ++IL +
Sbjct: 206 MSWQDHGRILRCQLSVANHRAQSE--IHLQVKYAPK--------------GVKILLSPSG 249
Query: 262 VPIQEGQSLFLACTVDSNPPA--SLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTC 319
I G+ + L C V+S+ PA S+ W ++G L + +G L LP + G +TC
Sbjct: 250 RNILPGELVTLTCQVNSSYPAVSSIKWLKDGVRLQ----TKTGVLHLPQAAWSDAGVYTC 305
Query: 320 RVQHPLGS 327
+ ++ +GS
Sbjct: 306 QAENGVGS 313
Score = 55.8 bits (133), Expect = 6e-08
Identities = 46/165 (27%), Positives = 72/165 (43%), Gaps = 25/165 (15%)
Query: 176 LTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYA 235
LT++W + LD + +T+ T+ C V G R + L+V YA
Sbjct: 1117 LTYTWYQDGQQRLDAHSIPLPNVTVRD-----ATSYRCGVGPPGRAPRLSRPITLDVLYA 1171
Query: 236 PQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKAL-N 294
P+NL ++ S+G GQ + CTVDS PPA L+ G+ L +
Sbjct: 1172 PRNLRLTYLLE----------SHG-------GQLALVLCTVDSRPPAQLALSHAGRLLAS 1214
Query: 295 PSQTSMSGTLELPNIG--AREGGEFTCRVQHPLGSQHLSFILSVQ 337
+ S+ TL L G R+ G ++C + PLG + S L ++
Sbjct: 1215 STAASVPNTLRLELRGPQPRDEGFYSCSARSPLGQANTSLELRLE 1259
Score = 48.5 bits (114), Expect = 1e-05
Identities = 58/218 (26%), Positives = 84/218 (38%), Gaps = 46/218 (21%)
Query: 154 LESGRPTRLSCSLPGSCEAGPPLTFSWTGN----ALSPLDPETTRSSELTLTPRPEDHGT 209
L+ G L+C++ AG P FSW N A PL+ +TL P
Sbjct: 719 LQEGTEANLTCNVSREA-AGSPANFSWFRNGVLWAQGPLET-------VTLLPVARTDAA 770
Query: 210 NLTCQVKRQ-GAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQ 268
C++ + GAQ++T V L+V Y P +S G G
Sbjct: 771 LYACRILTEAGAQLSTP--VLLSVLYPPDRPKLSALLDMGQGH----------------M 812
Query: 269 SLFLACTVDSNPPASLSWFRE----GKALNPSQTSM----------SGTLELPNIGAREG 314
+LF+ CTVDS P A L+ F +L P S S LE+ +G +
Sbjct: 813 ALFI-CTVDSRPLALLALFHGEHLLATSLGPQVPSHGRFQAKAEANSLKLEVRELGLGDS 871
Query: 315 GEFTCRVQHPLGSQHLSFILSVQRSSSSCICVTEKQQG 352
G + C + LGS + S V+ + E Q+G
Sbjct: 872 GSYRCEATNVLGSSNTSLFFQVRGAWVQVSPSPELQEG 909
Score = 45.8 bits (107), Expect = 7e-05
Identities = 57/209 (27%), Positives = 85/209 (40%), Gaps = 45/209 (21%)
Query: 134 KLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETT 193
+L LE +I P+ E G P ++C+ P A P ++W N +
Sbjct: 1255 ELRLEGVRVILAPEAAVPE----GAPITVTCADPA---AHAPTLYTWYHNGRWLQEGPAA 1307
Query: 194 RSSELTLTPRPEDHGTNLTCQVKRQGAQVT-TERTVQLNVSYAPQNLAISIFFRNGTGTA 252
S L T H +CQ Q AQ T + R L V YAPQ+ +S F R+ +
Sbjct: 1308 SLSFLVAT---RAHAGAYSCQA--QDAQGTRSSRPAALQVLYAPQDAVLSSF-RDSRARS 1361
Query: 253 LRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPS---QTSMSGT------ 303
+ ++ CTVDS PPA L+ +GK L S + SGT
Sbjct: 1362 MAVIQ----------------CTVDSEPPAELALSHDGKVLATSSGVHSLASGTGHVQVA 1405
Query: 304 -----LELPNIGAREGGEFTCRVQHPLGS 327
L++ ++ A + + C Q+ LGS
Sbjct: 1406 RNALRLQVQDVPAGD-DTYVCTAQNLLGS 1433
Score = 43.5 bits (101), Expect = 3e-04
Identities = 46/196 (23%), Positives = 71/196 (36%), Gaps = 40/196 (20%)
Query: 154 LESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTC 213
L+ G+ LSC + G + G L T R + +TLT H C
Sbjct: 906 LQEGQAVVLSCQVHTGVPEGTSYRWYRDGQPLQESTSATLRFAAITLTQAGAYH-----C 960
Query: 214 QVKRQGAQVTT-ERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFL 272
Q + G+ T+ + L+VSYAP+++ ++ G G +L
Sbjct: 961 QAQAPGSATTSLAAPISLHVSYAPRHVTLTTLMDTGPGRLGLLL---------------- 1004
Query: 273 ACTVDSNPPASLSWFREGKALNPSQTSMSG---------------TLELPNIGA--REGG 315
C VDS+PPA L + + + + G TL L GA + G
Sbjct: 1005 -CRVDSDPPAQLRLLHGDRLVASTLQGVGGPEGSSPRLHVAVAPNTLRLEIHGAMLEDEG 1063
Query: 316 EFTCRVQHPLGSQHLS 331
+ C + LG S
Sbjct: 1064 VYICEASNTLGQASAS 1079
Score = 43.1 bits (100), Expect = 4e-04
Identities = 24/66 (36%), Positives = 35/66 (53%), Gaps = 5/66 (7%)
Query: 261 SVPIQEGQSLFLACTVDSNPP--ASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFT 318
S +QEGQ++ L+C V + P S W+R+G+ P Q S S TL I + G +
Sbjct: 903 SPELQEGQAVVLSCQVHTGVPEGTSYRWYRDGQ---PLQESTSATLRFAAITLTQAGAYH 959
Query: 319 CRVQHP 324
C+ Q P
Sbjct: 960 CQAQAP 965
Score = 35.0 bits (79), Expect = 0.12
Identities = 21/70 (30%), Positives = 37/70 (52%), Gaps = 7/70 (10%)
Query: 264 IQEGQSLFLACTVDSNPPASL--SWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRV 321
++EGQ + L C V + PA L +W+++G+ Q + ++ LPN+ R+ + C V
Sbjct: 1097 VREGQLVNLTCLVWTTHPAQLTYTWYQDGQ-----QRLDAHSIPLPNVTVRDATSYRCGV 1151
Query: 322 QHPLGSQHLS 331
P + LS
Sbjct: 1152 GPPGRAPRLS 1161
>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
Length = 388
Score = 63.5 bits (153), Expect = 3e-10
Identities = 77/349 (22%), Positives = 128/349 (36%), Gaps = 70/349 (20%)
Query: 7 LPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEI 66
L LLW + E+Q + +VTV EG + C
Sbjct: 11 LLLLWAAAAGPGAGQEVQTE-NVTVAEGGVAEITCRLHQ--------------------- 48
Query: 67 PYYAEVVATNNPDRRV------KPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRV 120
Y +V NP R+ + RF+L + + + + DAR+ED G YF ++
Sbjct: 49 -YDGSIVVIQNPARQTLFFNGTRALKDERFQL-EEFSPRRVRIRLSDARLEDEGGYFCQL 106
Query: 121 ERGRDVKYSYQQNKLNLEVTALI--EKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTF 178
Y+ + +T L+ E P + E G LSC +P S P T
Sbjct: 107 -------YTEDTHHQIATLTVLVAPENPVVEVREQAVEGGEVELSCLVPRS---RPAATL 156
Query: 179 SWTGNALSPLDPETTR--------SSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQ- 229
W + +++ +S + +D G + C+ + Q + Q
Sbjct: 157 RWYRDRKELKGVSSSQENGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQY 216
Query: 230 -LNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNP-PASLSWF 287
L+V Y+P RI + ++EG +L L C V NP P + W
Sbjct: 217 VLDVQYSP---------------TARI--HASQAVVREGDTLVLTCAVTGNPRPNQIRWN 259
Query: 288 REGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSV 336
R ++L ++ TL LP + + + G +TC + G ++L V
Sbjct: 260 RGNESLPERAEAVGETLTLPGLVSADNGTYTCEASNKHGHARALYVLVV 308
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 61.6 bits (148), Expect = 1e-09
Identities = 50/186 (26%), Positives = 83/186 (44%), Gaps = 13/186 (6%)
Query: 157 GRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVK 216
G+ L+C + G A +T+ G +L P + S L P D G C+V
Sbjct: 2451 GQTLDLNCLVAGQAHA--QVTWHKRGGSL-PARHQVHGSRLRLLQVTPADSG-EYVCRVV 2506
Query: 217 RQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTV 276
G+ T E +V + + Q L+ S + G A + S + G +L L C V
Sbjct: 2507 --GSSGTQEASVLVTIQ---QRLSGS----HSQGVAYPVRIESSSASLANGHTLDLNCLV 2557
Query: 277 DSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSV 336
S P +++W++ G +L + L +P + + GE+ C V + GS+ S I+++
Sbjct: 2558 ASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTI 2617
Query: 337 QRSSSS 342
Q S SS
Sbjct: 2618 QGSGSS 2623
Score = 58.2 bits (139), Expect = 1e-08
Identities = 67/252 (26%), Positives = 103/252 (40%), Gaps = 23/252 (9%)
Query: 97 QKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQ---QNKLNLEVTALIEKPDIHFLEP 153
Q + L I A D G Y R G + + NL A +P +EP
Sbjct: 2290 QVRGSRLYIFQASPADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIR--IEP 2347
Query: 154 LES----GRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGT 209
S G+ L+C +PG A +T+ G +L P+ +T S P D G
Sbjct: 2348 SSSQVAEGQTLDLNCVVPGQSHA--QVTWHKRGGSL-PVRHQTHGSLLRLYQASPADSG- 2403
Query: 210 NLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQS 269
C+V G+ V E +V + + A A+ G +RI S+ S + EGQ+
Sbjct: 2404 EYVCRVL--GSSVPLEASVLVTIEPAGSVPAL------GVTPTVRIESS--SSQVAEGQT 2453
Query: 270 LFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQH 329
L L C V A ++W + G +L L L + + GE+ CRV G+Q
Sbjct: 2454 LDLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQE 2513
Query: 330 LSFILSVQRSSS 341
S ++++Q+ S
Sbjct: 2514 ASVLVTIQQRLS 2525
Score = 57.8 bits (138), Expect = 2e-08
Identities = 58/205 (28%), Positives = 79/205 (38%), Gaps = 23/205 (11%)
Query: 154 LESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPR--PEDHGTNL 211
+++G +L C G+ PPLTF W+ S L T +EL R PED G
Sbjct: 3310 VQAGETVQLQCLAHGT----PPLTFQWS-RVGSSLPGRATARNELLHFERAAPEDSG-RY 3363
Query: 212 TCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTA-----LRILSNGMSVPIQE 266
C+V + + E QL V P +L + T T L S G SV
Sbjct: 3364 RCRVTNKVG--SAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFH- 3420
Query: 267 GQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLG 326
C V S+ L WF+EG L P + G L + N+ G + C+ P G
Sbjct: 3421 -------CAVPSDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWG 3473
Query: 327 SQHLSFILSVQRSSSSCICVTEKQQ 351
S L +Q S I + Q
Sbjct: 3474 KAQASAQLVIQALPSVLINIRTSVQ 3498
Score = 57.4 bits (137), Expect = 2e-08
Identities = 52/193 (26%), Positives = 76/193 (39%), Gaps = 23/193 (11%)
Query: 154 LESGRPTRLSCSLPGSCEAGPPLTFSWT--GNALSPLDPETTRSSELTLTPR--PEDHGT 209
+ +GR RL C G P T +W G +L P L P D G
Sbjct: 1967 VHAGRTVRLYCRAAGV----PSATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGF 2022
Query: 210 NLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQS 269
L G + V L+ S A + ++I S+ SV EGQ+
Sbjct: 2023 YLCVATSPAGTAQARIQVVVLSASDA-------------SPPPVKIESSSPSVT--EGQT 2067
Query: 270 LFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQH 329
L L C V + A ++W+R G +L P L LP + + GE+ CRV++ G +
Sbjct: 2068 LDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKE 2127
Query: 330 LSFILSVQRSSSS 342
S +SV + S
Sbjct: 2128 ASITVSVLHGTHS 2140
Score = 53.1 bits (126), Expect = 4e-07
Identities = 38/155 (24%), Positives = 68/155 (43%), Gaps = 10/155 (6%)
Query: 199 TLTPRPEDHGTNLTCQ---VKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGT----GT 251
+L R + HG++L V G V N+ ++ IS+ G+ G+
Sbjct: 2669 SLPSRHQTHGSHLRLHQMSVADSGEYVCRANN---NIDALEASIVISVSPSAGSPSAPGS 2725
Query: 252 ALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGA 311
++ I S + EG++L L C V A ++W + G +L + L L ++
Sbjct: 2726 SMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSP 2785
Query: 312 REGGEFTCRVQHPLGSQHLSFILSVQRSSSSCICV 346
+ GE+ CRV G S +++++ S SS + V
Sbjct: 2786 ADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHV 2820
Score = 50.1 bits (118), Expect = 4e-06
Identities = 24/82 (29%), Positives = 41/82 (50%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCR 320
S + EGQ+L L C V P A ++W++ G +L + L L + + GE+ CR
Sbjct: 2638 SPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGEYVCR 2697
Query: 321 VQHPLGSQHLSFILSVQRSSSS 342
+ + + S ++SV S+ S
Sbjct: 2698 ANNNIDALEASIVISVSPSAGS 2719
Score = 49.3 bits (116), Expect = 6e-06
Identities = 52/199 (26%), Positives = 79/199 (39%), Gaps = 16/199 (8%)
Query: 143 IEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTP 202
IE H E G L+C +PG A +W S TR S L L
Sbjct: 2731 IESSSSHVAE----GETLDLNCVVPGQAHA----QVTWHKRGGSLPSHHQTRGSRLRLHH 2782
Query: 203 -RPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMS 261
P D G C+V G+ E +V + + A + A+ + G A I S
Sbjct: 2783 VSPADSG-EYVCRV--MGSSGPLEASVLVTIE-ASGSSAVHV---PAPGGAPPIRIEPSS 2835
Query: 262 VPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRV 321
+ EGQ+L L C V A ++W + G L L L + + GE++C+V
Sbjct: 2836 SRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQV 2895
Query: 322 QHPLGSQHLSFILSVQRSS 340
G+ S +++++ SS
Sbjct: 2896 TGSSGTLEASVLVTIEPSS 2914
Score = 45.4 bits (106), Expect = 9e-05
Identities = 51/200 (25%), Positives = 81/200 (40%), Gaps = 23/200 (11%)
Query: 151 LEPLES----GRPTRLSCSLPGSCEAGPPLTFSWTGNALSP---LDPETTRSSELTLTPR 203
+EP S G+ L C +PG A +T+ G L + R ++++
Sbjct: 2831 IEPSSSRVAEGQTLDLKCVVPGQAHA--QVTWHKRGGNLPARHQVHGPLLRLNQVS---- 2884
Query: 204 PEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVP 263
P D G +CQV G+ T E +V + + + + G A I S
Sbjct: 2885 PADSG-EYSCQVT--GSSGTLEASVLVTIEPSSPGPIPA------PGLAQPIYIEASSSH 2935
Query: 264 IQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCR-VQ 322
+ EGQ+L L C V A ++W++ G +L + L L + + GE+ CR
Sbjct: 2936 VTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAAS 2995
Query: 323 HPLGSQHLSFILSVQRSSSS 342
P Q SF ++V S S
Sbjct: 2996 GPGPEQEASFTVTVPPSEGS 3015
Score = 45.1 bits (105), Expect = 1e-04
Identities = 33/151 (21%), Positives = 63/151 (41%), Gaps = 12/151 (7%)
Query: 199 TLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGT--------- 249
+L P + HG+ L ++ + + E ++ P+ +I++ +GT
Sbjct: 2090 SLPPHTQVHGSRL--RLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPV 2147
Query: 250 -GTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPN 308
G+ I S + EGQ+L L C V A ++W + G +L + L L
Sbjct: 2148 PGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQ 2207
Query: 309 IGAREGGEFTCRVQHPLGSQHLSFILSVQRS 339
+ + GE+ C V G S +++++ S
Sbjct: 2208 VTPADSGEYVCHVVGTSGPLEASVLVTIEAS 2238
Score = 40.8 bits (94), Expect = 0.002
Identities = 54/232 (23%), Positives = 83/232 (35%), Gaps = 47/232 (20%)
Query: 112 DTGSYFFRVERGRDVKYSYQQNKLNLEVTAL--------------------IEKPDIHFL 151
D+G Y RVE G K + ++ V+ L IE H
Sbjct: 2111 DSGEYVCRVENGSGPK------EASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVA 2164
Query: 152 EPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNL 211
E G+ L+C +PG A +T+ G +L P +T S P D G
Sbjct: 2165 E----GQTLDLNCVVPGQAHA--QVTWHKRGGSL-PARHQTHGSLLRLHQVTPADSG-EY 2216
Query: 212 TCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLF 271
C V + V + S P G +RI S+ +V EGQ+L
Sbjct: 2217 VCHVVGTSGPLEASVLVTIEASVIP-----------GPIPPVRIESSSSTVA--EGQTLD 2263
Query: 272 LACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQH 323
L+C V A ++W++ G +L L + + G++ CR +
Sbjct: 2264 LSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRASN 2315
Score = 38.5 bits (88), Expect = 0.011
Identities = 20/87 (22%), Positives = 41/87 (47%), Gaps = 2/87 (2%)
Query: 252 ALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSG-TLELPNIG 310
A ++ + + ++ G + L C+ +P ++ W + L P Q + G TL +P +
Sbjct: 3211 APQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPL-PWQHRLEGDTLIIPRVA 3269
Query: 311 AREGGEFTCRVQHPLGSQHLSFILSVQ 337
++ G++ C P G + IL V+
Sbjct: 3270 QQDSGQYICNATSPAGHAEATIILHVE 3296
Score = 37.7 bits (86), Expect = 0.018
Identities = 63/323 (19%), Positives = 108/323 (33%), Gaps = 47/323 (14%)
Query: 17 EKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGE-IPYYAEVVAT 75
E P Y V + +VQ G V + C + +PPL W R G +P A
Sbjct: 3296 ESPPYATTVPEHASVQAGETVQLQCLA-------HGTPPLTFQWSRVGSSLPGRATARNE 3348
Query: 76 NNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKL 135
R PE GR+R C ++ E + G S
Sbjct: 3349 LLHFERAAPEDSGRYR---------CRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGST 3399
Query: 136 -NLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTR 194
++VT +E I G C++P + G L + G L P + +
Sbjct: 3400 PTVQVTPQLETKSI--------GASVEFHCAVPS--DRGTQLRWFKEGGQLPP--GHSVQ 3447
Query: 195 SSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALR 254
L + + CQ G + + QL + P L +
Sbjct: 3448 DGVLRIQNLDQSCQGTYICQA--HGPWGKAQASAQLVIQALPSVL-------------IN 3492
Query: 255 ILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREG 314
I ++ +V + G ++ C +P ++W + G L P G + + ++ +
Sbjct: 3493 IRTSVQTVVV--GHAVEFECLALGDPKPQVTWSKVGGHLRPGIVQSGGVVRIAHVELADA 3550
Query: 315 GEFTCRVQHPLGSQHLSFILSVQ 337
G++ C + G+ +L VQ
Sbjct: 3551 GQYRCTATNAAGTTQSHVLLLVQ 3573
Score = 36.6 bits (83), Expect = 0.041
Identities = 70/305 (22%), Positives = 100/305 (32%), Gaps = 47/305 (15%)
Query: 38 LVPCSFSYPWRSWYS-SPPLYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDV 96
+VP S+ R S SPP Y YW R+ P V TQ R +
Sbjct: 1687 IVPQGGSHSLRCQVSGSPPHYFYWSREDGRP--------------VPSGTQQRHQ----- 1727
Query: 97 QKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLES 156
L + D G Y + ++ L VT KP +E S
Sbjct: 1728 ---GSELHFPSVQPSDAGVYICTCRN----LHQSNTSRAELLVTEAPSKPITVTVEEQRS 1780
Query: 157 GRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPET-TRSSELTLTPRPEDHGTNLTC-- 213
S G +TF T + SP TR L R D LT
Sbjct: 1781 Q-----------SVRPGADVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRN 1829
Query: 214 -QVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFL 272
Q+ G V T N+ Q A +GT +A + + + +Q GQ
Sbjct: 1830 VQLSDAGTYVCTGS----NMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEF 1885
Query: 273 ACTVDSNPPASLSWFREGKALNPSQTSM-SGTLELPNIGAREGGEFTCRVQHPLGSQHLS 331
C+ +P +L W P++ + G L LP + + ++ CR G Q
Sbjct: 1886 RCSATGSPTPTLEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVAR 1945
Query: 332 FILSV 336
+L V
Sbjct: 1946 AVLHV 1950
Score = 35.0 bits (79), Expect = 0.12
Identities = 26/93 (27%), Positives = 38/93 (40%), Gaps = 3/93 (3%)
Query: 264 IQEGQSLFLACTVDSNPPASLSWFREGKALNPS---QTSMSGTLELPNIGAREGGEFTCR 320
+ +G S L C V +PP W RE PS Q L P++ + G + C
Sbjct: 1688 VPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPSDAGVYICT 1747
Query: 321 VQHPLGSQHLSFILSVQRSSSSCICVTEKQQGS 353
++ S L V + S I VT ++Q S
Sbjct: 1748 CRNLHQSNTSRAELLVTEAPSKPITVTVEEQRS 1780
Score = 33.1 bits (74), Expect = 0.45
Identities = 17/75 (22%), Positives = 30/75 (40%)
Query: 252 ALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGA 311
AL +S V + G + C P +SW + +L P + L LP++
Sbjct: 3574 ALPQISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRLENNMLMLPSVRP 3633
Query: 312 REGGEFTCRVQHPLG 326
++ G + C + G
Sbjct: 3634 QDAGTYVCTATNRQG 3648
>gi|47106069 sialic acid binding Ig-like lectin 15 [Homo sapiens]
Length = 328
Score = 60.8 bits (146), Expect = 2e-09
Identities = 59/201 (29%), Positives = 89/201 (44%), Gaps = 24/201 (11%)
Query: 21 YELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVV-----AT 75
+ +QV V+ + G ++PC+F++P R + PL W R GE PY V A
Sbjct: 44 WSMQVPPEVSAEAGDAAVLPCTFTHPHRHY--DGPLTAIW-RAGE-PYAGPQVFRCAAAR 99
Query: 76 NNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQ-QNK 134
+ + GRFRLLG+ ++ + SL + + D YF RVE DV Y+ ++
Sbjct: 100 GSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALADDRRYFCRVEFAGDVHDRYESRHG 159
Query: 135 LNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTR 194
+ L VTA +I L R C+ G PP +W+G AL
Sbjct: 160 VRLHVTAAPRIVNISVLP--SPAHAFRALCTAEGE----PPPALAWSGPALG-------N 206
Query: 195 SSELTLTPRPEDHGTNLTCQV 215
S +PR E HG +T ++
Sbjct: 207 SLAAVRSPR-EGHGHLVTAEL 226
Score = 30.4 bits (67), Expect = 2.9
Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 13/70 (18%)
Query: 274 CTVDSNPPASLSWFREGKALNPSQTSMSG---------TLELPNIGAREGGEFTCRVQHP 324
CT + PP +L+W G AL S ++ T ELP + G +TC +
Sbjct: 187 CTAEGEPPPALAW--SGPALGNSLAAVRSPREGHGHLVTAELPAL--THDGRYTCTAANS 242
Query: 325 LGSQHLSFIL 334
LG S L
Sbjct: 243 LGRSEASVYL 252
>gi|18201909 vascular cell adhesion molecule 1 isoform b precursor
[Homo sapiens]
Length = 647
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/217 (24%), Positives = 88/217 (40%), Gaps = 29/217 (13%)
Query: 135 LNLEVTALIEKPDIHFLEPLESGRPTRLSCS---------LPGSCEAGPPLTFSWTGNAL 185
+ +E+ + + P+IH PLE+G+P + CS L G L S
Sbjct: 108 IQVEIYSFPKDPEIHLSGPLEAGKPITVKCSVADVYPFDRLEIDLLKGDHLMKSQEFLED 167
Query: 186 SPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTV-----QLNVSYAPQNLA 240
+ T+S E+T TP ED G L C+ K ++ + TV +L V +P+N
Sbjct: 168 ADRKSLETKSLEVTFTPVIEDIGKVLVCRAKLHIDEMDSVPTVRQAVKELQVYISPKNTV 227
Query: 241 ISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSM 300
IS+ S +QEG S+ + C+ + P + W ++ N S
Sbjct: 228 ISV---------------NPSTKLQEGGSVTMTCSSEGLPAPEIFWSKKLDNGNLQHLSG 272
Query: 301 SGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ 337
+ TL L + + G + C + +G L VQ
Sbjct: 273 NATLTLIAMRMEDSGIYVCEGVNLIGKNRKEVELIVQ 309
Score = 44.7 bits (104), Expect = 1e-04
Identities = 57/247 (23%), Positives = 96/247 (38%), Gaps = 23/247 (9%)
Query: 100 NCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRP 159
N +L++ RMED+G Y V G ++ + ++ L V A P+I L +G
Sbjct: 273 NATLTLIAMRMEDSGIY---VCEGVNL-IGKNRKEVELIVQAFPRDPEIEMSGGLVNGSS 328
Query: 160 TRLSCSLPG-------SCEAGPPLTFSWTGNALSPLDPET--TRSSELTLTPRPEDHGTN 210
+SC +P E T L D ++ +S E+T P ED G
Sbjct: 329 VTVSCKVPSVYPLDRLEIELLKGETILENIEFLEDTDMKSLENKSLEMTFIPTIEDTGKA 388
Query: 211 LTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSL 270
L CQ K + + + Q L +++ R+ T +L + S+ ++EG S+
Sbjct: 389 LVCQAKLH----IDDMEFEPKQRQSTQTLYVNVAPRDTT-----VLVSPSSI-LEEGSSV 438
Query: 271 FLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHL 330
+ C P + W R+ S + TL L + + G + C + G
Sbjct: 439 NMTCLSQGFPAPKILWSRQLPNGELQPLSENATLTLISTKMEDSGVYLCEGINQAGRSRK 498
Query: 331 SFILSVQ 337
L +Q
Sbjct: 499 EVELIIQ 505
Score = 39.3 bits (90), Expect = 0.006
Identities = 35/185 (18%), Positives = 76/185 (41%), Gaps = 23/185 (12%)
Query: 154 LESGRPTRLSCSLPGSCEAGPPLTFSWTGNALS-PLDPETTRSSELTLTPRPEDHGTNLT 212
LE G ++C G P W+ + L P + ++ ++ + ED G L
Sbjct: 432 LEEGSSVNMTCLSQGF----PAPKILWSRQLPNGELQPLSENATLTLISTKMEDSGVYLC 487
Query: 213 CQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFL 272
+ + G + + V+L + P+++ ++ F S ++EG ++ +
Sbjct: 488 EGINQAGR---SRKEVELIIQVTPKDIKLTAF---------------PSESVKEGDTVII 529
Query: 273 ACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSF 332
+CT + P + ++ + + S+ G + ++ G + C ++ +GSQ S
Sbjct: 530 SCTCGNVPETWIILKKKAETGDTVLKSIDGAYTIRKAQLKDAGVYECESKNKVGSQLRSL 589
Query: 333 ILSVQ 337
L VQ
Sbjct: 590 TLDVQ 594
>gi|4507875 vascular cell adhesion molecule 1 isoform a precursor
[Homo sapiens]
Length = 739
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/217 (24%), Positives = 88/217 (40%), Gaps = 29/217 (13%)
Query: 135 LNLEVTALIEKPDIHFLEPLESGRPTRLSCS---------LPGSCEAGPPLTFSWTGNAL 185
+ +E+ + + P+IH PLE+G+P + CS L G L S
Sbjct: 108 IQVEIYSFPKDPEIHLSGPLEAGKPITVKCSVADVYPFDRLEIDLLKGDHLMKSQEFLED 167
Query: 186 SPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTV-----QLNVSYAPQNLA 240
+ T+S E+T TP ED G L C+ K ++ + TV +L V +P+N
Sbjct: 168 ADRKSLETKSLEVTFTPVIEDIGKVLVCRAKLHIDEMDSVPTVRQAVKELQVYISPKNTV 227
Query: 241 ISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSM 300
IS+ S +QEG S+ + C+ + P + W ++ N S
Sbjct: 228 ISV---------------NPSTKLQEGGSVTMTCSSEGLPAPEIFWSKKLDNGNLQHLSG 272
Query: 301 SGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ 337
+ TL L + + G + C + +G L VQ
Sbjct: 273 NATLTLIAMRMEDSGIYVCEGVNLIGKNRKEVELIVQ 309
Score = 42.7 bits (99), Expect = 6e-04
Identities = 70/339 (20%), Positives = 118/339 (34%), Gaps = 65/339 (19%)
Query: 15 LQEKP-VYELQVQKSVTVQEGLCVLVPCSF------SYPWRSWYSSPPLYVYWFRDGEIP 67
+QEKP E+ + Q G V++ CS S+ WR+ SP
Sbjct: 308 VQEKPFTVEISPGPRIAAQIGDSVMLTCSVMGCESPSFSWRTQIDSP------------- 354
Query: 68 YYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVK 127
G+ R G N +L++ E+ SY V G
Sbjct: 355 ------------------LSGKVRSEGT----NSTLTLSPVSFENEHSYLCTVTCG---- 388
Query: 128 YSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPG-------SCEAGPPLTFSW 180
+ + + +E+ + P+I L +G +SC +P E T
Sbjct: 389 HKKLEKGIQVELYSFPRDPEIEMSGGLVNGSSVTVSCKVPSVYPLDRLEIELLKGETILE 448
Query: 181 TGNALSPLDPET--TRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQN 238
L D ++ +S E+T P ED G L CQ K + + + Q
Sbjct: 449 NIEFLEDTDMKSLENKSLEMTFIPTIEDTGKALVCQAKLH----IDDMEFEPKQRQSTQT 504
Query: 239 LAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQT 298
L +++ R+ T +L + S+ ++EG S+ + C P + W R+
Sbjct: 505 LYVNVAPRDTT-----VLVSPSSI-LEEGSSVNMTCLSQGFPAPKILWSRQLPNGELQPL 558
Query: 299 SMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ 337
S + TL L + + G + C + G L +Q
Sbjct: 559 SENATLTLISTKMEDSGVYLCEGINQAGRSRKEVELIIQ 597
Score = 39.3 bits (90), Expect = 0.006
Identities = 35/185 (18%), Positives = 76/185 (41%), Gaps = 23/185 (12%)
Query: 154 LESGRPTRLSCSLPGSCEAGPPLTFSWTGNALS-PLDPETTRSSELTLTPRPEDHGTNLT 212
LE G ++C G P W+ + L P + ++ ++ + ED G L
Sbjct: 524 LEEGSSVNMTCLSQGF----PAPKILWSRQLPNGELQPLSENATLTLISTKMEDSGVYLC 579
Query: 213 CQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFL 272
+ + G + + V+L + P+++ ++ F S ++EG ++ +
Sbjct: 580 EGINQAGR---SRKEVELIIQVTPKDIKLTAF---------------PSESVKEGDTVII 621
Query: 273 ACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSF 332
+CT + P + ++ + + S+ G + ++ G + C ++ +GSQ S
Sbjct: 622 SCTCGNVPETWIILKKKAETGDTVLKSIDGAYTIRKAQLKDAGVYECESKNKVGSQLRSL 681
Query: 333 ILSVQ 337
L VQ
Sbjct: 682 TLDVQ 686
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 57.4 bits (137), Expect = 2e-08
Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 11/115 (9%)
Query: 249 TGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPS------QTSMSG 302
T A RIL+ S+ + EG+S +C D P +++W R+G+ L+ S T
Sbjct: 32557 TTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKS 32616
Query: 303 TLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSSSCICVTEKQQGSWPLV 357
T E+ ++ A + G ++ V++ G Q F L++Q++ VTEK S P V
Sbjct: 32617 TFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR-----VTEKAVTSPPRV 32666
Score = 53.5 bits (127), Expect = 3e-07
Identities = 62/300 (20%), Positives = 108/300 (36%), Gaps = 59/300 (19%)
Query: 53 SPPLYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMED 112
S P+ V WF+DG+ E+ A++ R+R+ + SL I M D
Sbjct: 4139 SLPMRVSWFKDGK-----EIAASD------------RYRIA--FVEGTASLEIIRVDMND 4179
Query: 113 TGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEA 172
G++ R K S ++++P +P + L + +
Sbjct: 4180 AGNFTCRATNSVGSKDS--------SGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQG 4231
Query: 173 GPPLTFSW-------TGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTE 225
PLT W + E SS + D GT TC+V V
Sbjct: 4232 STPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGT-YTCKVSNVAGGV--- 4287
Query: 226 RTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLS 285
+ ++F + ++ + + +++G + LAC V PP ++
Sbjct: 4288 ------------ECSANLFVKEPATFVEKLEPSQL---LKKGDATQLACKVTGTPPIKIT 4332
Query: 286 WFREGKALNPSQ------TSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRS 339
WF + + S + L L ++G + GE+ C Q+ GS H S I+ V+ S
Sbjct: 4333 WFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKES 4392
Score = 51.2 bits (121), Expect = 2e-06
Identities = 62/287 (21%), Positives = 112/287 (39%), Gaps = 62/287 (21%)
Query: 73 VATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFF-------------- 118
V+ + D+++KP R D + L I +A ED G+Y F
Sbjct: 3375 VSWYSKDKKIKPSRFFRMTQFEDTYQ----LEIAEAYPEDEGTYTFVASNAVGQVSSTAN 3430
Query: 119 -RVERGRDVKYSYQQNKLNLEVTA--LIEKPDIHFLEPLES--GRPTRLSCSLPGSCEAG 173
+E + + + ++ +E+ A +I++ +EPLE G + +C + ++
Sbjct: 3431 LSLEAPESILHERIEQEIEMEMKAAPVIKRK----IEPLEVALGHLAKFTCEI----QSA 3482
Query: 174 PPLTFSW--TGNALSPLDPETTRSSELT-----LTPRPEDHGTNLTCQVKRQGAQVTTER 226
P + F W G + D + RSS+ L + D G TC+ + V+
Sbjct: 3483 PNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCG-EYTCKASNEYGSVSCTA 3541
Query: 227 TVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSW 286
T+ + +Y P LS S+ G++ CTV P W
Sbjct: 3542 TLTVTEAYPPT-----------------FLSRPKSLTTFVGKAAKFICTVTGTPVIETIW 3584
Query: 287 FREGKALNP------SQTSMSGTLELPNIGAREGGEFTCRVQHPLGS 327
++G AL+P S LEL N+ ++ G ++C+ + G+
Sbjct: 3585 QKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGA 3631
Score = 49.7 bits (117), Expect = 5e-06
Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 19/111 (17%)
Query: 272 LACTVDSNPPASLSWFREGKALNPSQ------TSMSGTLELPNIGAREGGEFTCRVQHPL 325
L C + + P +SWF++GK + S + +LE+ + + G FTCR + +
Sbjct: 4132 LDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSV 4191
Query: 326 GSQHLSFILSVQRSSS-------------SCICVTEKQQGSWPLVLTLIRG 363
GS+ S L VQ S S +C+ QGS PL + +G
Sbjct: 4192 GSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKG 4242
Score = 49.3 bits (116), Expect = 6e-06
Identities = 55/262 (20%), Positives = 101/262 (38%), Gaps = 46/262 (17%)
Query: 98 KKNCSLSIGDARMEDTGSYFFRVER--GRDVKYSYQQNKLNLEVTALIEKPD-IHFLEPL 154
+K C L I ++ D G Y +E GRDV + + + +E P + LEPL
Sbjct: 6038 EKTCILEILNSTKRDAGQYSCEIENEAGRDVCGA---------LVSTLEPPYFVTELEPL 6088
Query: 155 ES--GRPTRLSCSLPGSCEAGPPLTFSW-TGNALSPLDPE-----TTRSSELTLTPRPED 206
E+ G L C + G+ P +T SW G+ PE T + L +
Sbjct: 6089 EAAVGDSVSLQCQVAGT----PEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNIN 6144
Query: 207 HGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQE 266
TC+ + +++ ++ P + A L+ + + +P+
Sbjct: 6145 DSGEYTCKAENSIGTASSKTVFRIQERQLPPSFA----------RQLKDIEQTVGLPVT- 6193
Query: 267 GQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSG------TLELPNIGAREGGEFTCR 320
L C ++ + P + W+R+G L + + TL++ G+++C
Sbjct: 6194 -----LTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCS 6248
Query: 321 VQHPLGSQHLSFILSVQRSSSS 342
+PLG+ S L+ + S
Sbjct: 6249 ASNPLGTASSSARLTAREPKKS 6270
Score = 46.2 bits (108), Expect = 5e-05
Identities = 66/290 (22%), Positives = 111/290 (38%), Gaps = 61/290 (21%)
Query: 53 SPPLYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMED 112
+PP+ V W ++G P +R T +K+ L I + +ED
Sbjct: 7894 TPPISVTWKKNG---------INVTPSQRCNITTT----------EKSAILEIPSSTVED 7934
Query: 113 TGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLES--GRPTRLSCSLPGSC 170
G Y +E K S L LE +++ LEP++ G L C L G+
Sbjct: 7935 AGQYNCYIENASG-KDSCSAQILILEPPYFVKQ-----LEPVKVSVGDSASLQCQLAGTP 7988
Query: 171 EAGPPLTFSWTGNALSPLDPETT-----RSSELTLTPRPEDHGTN--LTCQVKRQGAQVT 223
E G SW + L P TT R++ TL D + C+ + +V+
Sbjct: 7989 EIG----VSWYKGD-TKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVS 8043
Query: 224 TERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPAS 283
+ + P + + LR + + +P+ C + + P S
Sbjct: 8044 ASTFLTVQEQKLPPSFS----------RQLRDVQETVGLPV------VFDCAISGSEPIS 8087
Query: 284 LSWFREGKALNPS---QTSM---SGTLELPNIGAREGGEFTCRVQHPLGS 327
+SW+++GK L S QTS + TL + G+++C +P+GS
Sbjct: 8088 VSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGS 8137
Score = 44.7 bits (104), Expect = 1e-04
Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 267 GQSLFLACTVDSNPPASLSWFREGKALNPSQT------SMSGTLELPNIGAREGGEFTCR 320
G S+ + C V + P S WF++GK ++ S S +LE+ N+ + +TC+
Sbjct: 5251 GSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCK 5310
Query: 321 VQHPLGSQHLSFILSVQRSSS 341
V + G S IL+V+ S
Sbjct: 5311 VSNVAGDDACSGILTVKEPPS 5331
Score = 44.7 bits (104), Expect = 1e-04
Identities = 55/255 (21%), Positives = 98/255 (38%), Gaps = 42/255 (16%)
Query: 102 SLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLE--SGRP 159
+L +G ++G Y +++ ++ + LE +IEKP EP+ +G P
Sbjct: 6608 TLQLGSPEASNSGKYICQIKNDAGMRECSAVLTV-LEPARIIEKP-----EPMTVTTGNP 6661
Query: 160 TRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQG 219
L C + G+ P L+ W + EL+ + N +K
Sbjct: 6662 FALECVVTGT----PELSAKWFKDG-----------RELSADSKHHITFINKVASLKIPC 6706
Query: 220 AQVTTERTVQLNV--SYAPQNLAISIFFRNGTGTALRILSNGMSVPIQE-----GQSLFL 272
A+++ + V S N +S+ + RI+ +++ G S+ L
Sbjct: 6707 AEMSDKGLYSFEVKNSVGKSNCTVSVHVSD------RIVPPSFIRKLKDVNAILGASVVL 6760
Query: 273 ACTVDSNPPASLSWFREGKALNPSQTSMSG------TLELPNIGAREGGEFTCRVQHPLG 326
C V + P S+ WF++G + S TL L + + G +TC + G
Sbjct: 6761 ECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAG 6820
Query: 327 SQHLSFILSVQRSSS 341
S S +L+VQ S
Sbjct: 6821 SDECSAVLTVQEPPS 6835
Score = 44.7 bits (104), Expect = 1e-04
Identities = 47/212 (22%), Positives = 81/212 (38%), Gaps = 28/212 (13%)
Query: 148 IHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDP-ETTRSSELTLTPRPED 206
++ LE +SG T ++ ++ GS E PLT + + DP + + +T T +
Sbjct: 7741 VNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKG 7800
Query: 207 HGTNLTCQVKRQGAQVTTER-TVQLNVSYAPQNLAISIFFRNGTGTAL------------ 253
K V +R V L S A L ++G T +
Sbjct: 7801 TPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTT 7860
Query: 254 --------RILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ------TS 299
+ + I++G+ L L T PP S++W + G + PSQ T
Sbjct: 7861 HLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTE 7920
Query: 300 MSGTLELPNIGAREGGEFTCRVQHPLGSQHLS 331
S LE+P+ + G++ C +++ G S
Sbjct: 7921 KSAILEIPSSTVEDAGQYNCYIENASGKDSCS 7952
Score = 44.7 bits (104), Expect = 1e-04
Identities = 36/171 (21%), Positives = 68/171 (39%), Gaps = 16/171 (9%)
Query: 163 SCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQV 222
S L G P+T +W N + + + T + E+T L QV++ G
Sbjct: 8266 SFKLEGRVAGSQPITVAWYKNNI---EIQPTSNCEITFK------NNTLVLQVRKAGMND 8316
Query: 223 TTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPA 282
T +++ SI + + + V + EG+ + L+C V + P
Sbjct: 8317 AGLYTCKVSNDAGSALCTSSIVIKEPKKPPV-FDQHLTPVTVSEGEYVQLSCHVQGSEPI 8375
Query: 283 SLSWFREGKALNPSQ------TSMSGTLELPNIGAREGGEFTCRVQHPLGS 327
+ W + G+ + PS S + LEL ++ + G++ C+ + GS
Sbjct: 8376 RIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGS 8426
Score = 43.1 bits (100), Expect = 4e-04
Identities = 51/210 (24%), Positives = 85/210 (40%), Gaps = 36/210 (17%)
Query: 141 ALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAG-PPLTFSWTGNALSPLDPETTR----- 194
AL E P F++ +E+ S + S AG PP++ +W + LD +
Sbjct: 5043 ALKEPPS--FIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDD-QILDEDDNVYISFV 5099
Query: 195 SSELTLTPRPEDHGTN--LTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTA 252
S TL R D+G + TCQ K + ER + P
Sbjct: 5100 DSVATLQIRSVDNGHSGRYTCQAKNESG---VERCYAFLLVQEPA--------------- 5141
Query: 253 LRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ-TSMS-----GTLEL 306
+I+ SV + E + L C V P + W ++GK + PS+ SMS + +
Sbjct: 5142 -QIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRI 5200
Query: 307 PNIGAREGGEFTCRVQHPLGSQHLSFILSV 336
++ ++ G++T +V++ GS L V
Sbjct: 5201 QSVMKQDSGQYTFKVENDFGSSSCDAYLRV 5230
Score = 43.1 bits (100), Expect = 4e-04
Identities = 58/298 (19%), Positives = 111/298 (37%), Gaps = 69/298 (23%)
Query: 49 SWYSSPPLYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDA 108
++ +PP+ V W +D + +E R + +K+ L I ++
Sbjct: 6949 TYTGTPPISVSWIKDEYLISQSE-------------------RCSITMTEKSTILEILES 6989
Query: 109 RMEDTGSYFFRVER--GRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLES-----GRPTR 161
+ED Y +E G+D+ + + +++E P +F+EPLE G P
Sbjct: 6990 TIEDYAQYSCLIENEAGQDICEA---------LVSVLEPP--YFIEPLEHVEAVIGEPAT 7038
Query: 162 LSCSLPGSCEAGPPLTFSW----TGNALSPLDPETTRSSELTLTPRPEDHGT--NLTCQV 215
L C + G+ P + SW T +P +++ +L DH +C+
Sbjct: 7039 LQCKVDGT----PEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKA 7094
Query: 216 KRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACT 275
V + + + P A L+ + + P+ C
Sbjct: 7095 DNSVGAVASSAVLVIKARKLPPFFA----------RKLKDVHETLGFPVA------FECR 7138
Query: 276 VDSNPPASLSWFREGKALNPS---QTSM---SGTLELPNIGAREGGEFTCRVQHPLGS 327
++ + P +SW+++G L QTS TL++ G++ C +PLG+
Sbjct: 7139 INGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGT 7196
Score = 43.1 bits (100), Expect = 4e-04
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 8/89 (8%)
Query: 255 ILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ-------TSMSGTLELP 307
I+ S+ + G + L CTV P S WF++GK L +SG L++
Sbjct: 7588 IVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSG-LKII 7646
Query: 308 NIGAREGGEFTCRVQHPLGSQHLSFILSV 336
N+ + G ++ VQ+P+G + L V
Sbjct: 7647 NVAPSDSGVYSFEVQNPVGKDSCTASLQV 7675
Score = 42.7 bits (99), Expect = 6e-04
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 11/91 (12%)
Query: 257 SNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ------TSMSGTLELPNIG 310
+NG+S G S+ + C V +PP S+SWF EG ++ + T + L + +
Sbjct: 7691 TNGLS-----GSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLE 7745
Query: 311 AREGGEFTCRVQHPLGSQHLSFILSVQRSSS 341
+ G++TC + GS S L+V+ S
Sbjct: 7746 ESDSGDYTCIATNMAGSDECSAPLTVREPPS 7776
Score = 42.0 bits (97), Expect = 0.001
Identities = 38/197 (19%), Positives = 73/197 (37%), Gaps = 37/197 (18%)
Query: 154 LESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPE------TTRSSELTLTPRPEDH 207
+E G+P L + G+ PP++ +W N ++ + T +S+ L + +
Sbjct: 7879 IEKGKPLILEGTFTGT----PPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVED 7934
Query: 208 GTNLTCQVKR-QGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQE 266
C ++ G + + + L Y + L V +
Sbjct: 7935 AGQYNCYIENASGKDSCSAQILILEPPYFVKQLE--------------------PVKVSV 7974
Query: 267 GQSLFLACTVDSNPPASLSWFREGKALNPSQT------SMSGTLELPNIGAREGGEFTCR 320
G S L C + P +SW++ L P+ T + TL + + GE+ C+
Sbjct: 7975 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICK 8034
Query: 321 VQHPLGSQHLSFILSVQ 337
++ +G S L+VQ
Sbjct: 8035 AENSVGEVSASTFLTVQ 8051
Score = 41.6 bits (96), Expect = 0.001
Identities = 39/133 (29%), Positives = 59/133 (44%), Gaps = 10/133 (7%)
Query: 215 VKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLAC 274
V+RQ A T + VQ NV + + + R + R L N V G S L C
Sbjct: 5766 VERQDAGTYTFQ-VQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVL---GASCILEC 5821
Query: 275 TVDSNPPASLSWFREGKALNPS---QTSMSG---TLELPNIGAREGGEFTCRVQHPLGSQ 328
V + P S++WF E + QT+ S TL+L ++ + + G +TC + GS
Sbjct: 5822 KVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSD 5881
Query: 329 HLSFILSVQRSSS 341
+L+VQ S
Sbjct: 5882 ECRAVLTVQEPPS 5894
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 9/104 (8%)
Query: 255 ILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPS----QTSMSG--TLELPN 308
++S +V + EG+S+ L C + P +++W+RE + S T SG L +
Sbjct: 945 LVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIRE 1004
Query: 309 IGAREGGEFTCRVQHPLGSQHLSFILSVQRS---SSSCICVTEK 349
A + G FTC + G+ S L+VQ S VTEK
Sbjct: 1005 AFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEK 1048
Score = 40.8 bits (94), Expect = 0.002
Identities = 70/328 (21%), Positives = 117/328 (35%), Gaps = 76/328 (23%)
Query: 18 KPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVVATNN 77
+P ++ +S+ V G + C+ + +P L WF+DG+ E+ + N
Sbjct: 7584 EPATIVEKPESIKVTTGDTCTLECTVA-------GTPELSTKWFKDGK-----ELTSDN- 7630
Query: 78 PDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVER--GRDVKYSYQQNKL 135
++++ K L I + D+G Y F V+ G+D
Sbjct: 7631 -----------KYKI--SFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKD------SCTA 7671
Query: 136 NLEVTALIEKPDIHFLEPLE-----SGRPTRLSCSLPGSCEAGPPLTFSW--TGNALSP- 187
+L+V+ P F L+ SG + C + GS PP++ SW GN +S
Sbjct: 7672 SLQVSDRTVPPS--FTRKLKETNGLSGSSVVMECKVYGS----PPISVSWFHEGNEISSG 7725
Query: 188 ---LDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIF 244
T + LT+ E + TC + E + L V P
Sbjct: 7726 RKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAG--SDECSAPLTVREPPS------- 7776
Query: 245 FRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFR------EGKALNPSQT 298
+ + + G ++ V PP S+SWF+ G N S
Sbjct: 7777 ----------FVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLE 7826
Query: 299 SMSGTLELPNIGAREGGEFTCRVQHPLG 326
LEL ++ + GE+TC V + G
Sbjct: 7827 DSVAELELFDVDTSQSGEYTCIVSNEAG 7854
Score = 40.4 bits (93), Expect = 0.003
Identities = 60/273 (21%), Positives = 98/273 (35%), Gaps = 60/273 (21%)
Query: 102 SLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGR--P 159
+ I AR+E++G+Y + K+ T + E L+P+E +
Sbjct: 4918 TFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRE------LKPVEVVKYSD 4971
Query: 160 TRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPR------------PEDH 207
L C + G+ PP +W N + E S + TLT R P D
Sbjct: 4972 VELECEVTGT----PPFEVTWLKN-----NREIRSSKKYTLTDRVSVFNLHITKCDPSDT 5022
Query: 208 GTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEG 267
G C V +G + V L P + I T T L+
Sbjct: 5023 G-EYQCIVSNEGGSCSCSTRVALK---EPPSFIKKI---ENTTTVLK------------- 5062
Query: 268 QSLFLACTVDSNPPASLSWFREGKALNP------SQTSMSGTLELPNIGAREGGEFTCRV 321
S TV +PP S++W ++ + L+ S TL++ ++ G +TC+
Sbjct: 5063 SSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQA 5122
Query: 322 QHPLGSQHLSFILSVQR-----SSSSCICVTEK 349
++ G + L VQ + + VTEK
Sbjct: 5123 KNESGVERCYAFLLVQEPAQIVEKAKSVDVTEK 5155
Score = 39.3 bits (90), Expect = 0.006
Identities = 20/88 (22%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 255 ILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQT------SMSGTLELPN 308
I+ + + G++ L C V P S+ W+++GK L SQ + +L + +
Sbjct: 5706 IVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILS 5765
Query: 309 IGAREGGEFTCRVQHPLGSQHLSFILSV 336
+ ++ G +T +VQ+ +G + ++ V
Sbjct: 5766 VERQDAGTYTFQVQNNVGKSSCTAVVDV 5793
Score = 39.3 bits (90), Expect = 0.006
Identities = 69/299 (23%), Positives = 102/299 (34%), Gaps = 55/299 (18%)
Query: 67 PYYAEVVATNNPDRRVKPETQGRFRLLGDVQ------KKNCSLSIGDARMEDTGSYFFRV 120
P+ E V T P+ K GR L D + K SL I A M D G Y F V
Sbjct: 6661 PFALECVVTGTPELSAKWFKDGR-ELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEV 6719
Query: 121 ERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLES-----GRPTRLSCSLPGSCEAGPP 175
+ +++ V+ I P F+ L+ G L C + GS P
Sbjct: 6720 KNS----VGKSNCTVSVHVSDRIVPPS--FIRKLKDVNAILGASVVLECRVSGSA----P 6769
Query: 176 LTFSW--TGNAL--SPLDPETTRSSELTLTP---RPEDHGTNLTCQVKRQGAQVTTERTV 228
++ W GN + P + + TL P D G G+ E +
Sbjct: 6770 ISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSD---ECSA 6826
Query: 229 QLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFR 288
L V P SV + G SL + PP + WF+
Sbjct: 6827 VLTVQEPPS-----------------FEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFK 6869
Query: 289 ------EGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSS 341
G++ N S LEL + E G+++C V + GS + L V+ ++
Sbjct: 6870 GSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPAT 6928
Score = 38.5 bits (88), Expect = 0.011
Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Query: 265 QEGQSLFLACTVDSNPPASLSWFREGKAL------NPSQTSMSGTLELPNIGAREGGEFT 318
++G+S+ L C + +P +SWFR L N S + L + A + G++
Sbjct: 6377 KQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYI 6436
Query: 319 CRVQHPLGSQHLSFILSVQ 337
C + +G S L+V+
Sbjct: 6437 CEAHNGVGDASCSTALTVK 6455
Score = 38.1 bits (87), Expect = 0.014
Identities = 44/201 (21%), Positives = 79/201 (39%), Gaps = 48/201 (23%)
Query: 157 GRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVK 216
G P L+C L GS P+ W + + D E ++S +
Sbjct: 6189 GLPVTLTCRLNGSA----PIQVCWYRDGVLLRDDENLQTSFVD----------------- 6227
Query: 217 RQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTA---LRILSNG-----------MSV 262
V T + +Q ++S++ Q S N GTA R+ + +S+
Sbjct: 6228 ----NVATLKILQTDLSHSGQ---YSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSI 6280
Query: 263 PIQEGQSLFLACTVDSNPPASLSWFREGKALNP----SQTSMSGT--LELPNIGAREGGE 316
+ G+S C V P ++W ++ K + P + T + T L + +G + G+
Sbjct: 6281 DVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQ 6340
Query: 317 FTCRVQHPLGSQHLSFILSVQ 337
+TC+ + +G S LSV+
Sbjct: 6341 YTCQATNDVGKDMCSAQLSVK 6361
Score = 38.1 bits (87), Expect = 0.014
Identities = 57/334 (17%), Positives = 117/334 (35%), Gaps = 62/334 (18%)
Query: 14 SLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVV 73
S++E P + +++ S ++G + + C S SP + V WFR+
Sbjct: 6359 SVKEPPKFVKKLEASKVAKQGESIQLECKIS-------GSPEIKVSWFRN---------- 6401
Query: 74 ATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQN 133
D + + + V L+I +A ED+G Y G
Sbjct: 6402 -----DSELHESWKYNMSFINSV----ALLTINEASAEDSGDYICEAHNG--------VG 6444
Query: 134 KLNLEVTALIEKPDIHFLEPLE----SGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLD 189
+ ++ P + +P G L C + G+ PP W +
Sbjct: 6445 DASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGT----PPFEVVWVKDR----- 6495
Query: 190 PETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGT 249
+ S + +T + D + + A E + + S+ F+
Sbjct: 6496 KQVRNSKKFKITSKHFD----TSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPP 6551
Query: 250 GTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFRE-GKALNPSQTSMSG------ 302
++ + G ++ L V+ P S+ W ++ G+ + S+ +
Sbjct: 6552 RFVKKLSDTSTLI----GDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIA 6607
Query: 303 TLELPNIGAREGGEFTCRVQHPLGSQHLSFILSV 336
TL+L + A G++ C++++ G + S +L+V
Sbjct: 6608 TLQLGSPEASNSGKYICQIKNDAGMRECSAVLTV 6641
Score = 37.7 bits (86), Expect = 0.018
Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 8/87 (9%)
Query: 263 PIQEG--QSLFLACTVDSNPPASLSWFREGKALNPSQT------SMSGTLELPNIGAREG 314
P+Q + + L C VD + +++W ++G+ L P + TLE+P ++
Sbjct: 3652 PVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDS 3711
Query: 315 GEFTCRVQHPLGSQHLSFILSVQRSSS 341
G + C + GS S ++V+ S
Sbjct: 3712 GTYVCTASNEAGSSSCSATVTVREPPS 3738
Score = 37.4 bits (85), Expect = 0.024
Identities = 18/81 (22%), Positives = 38/81 (46%), Gaps = 6/81 (7%)
Query: 267 GQSLFLACTVDSNPPASLSWFREGKALNPSQT------SMSGTLELPNIGAREGGEFTCR 320
G+S L C + +P ++WF+ K L+ S T + L++ ++ + G ++C
Sbjct: 3752 GESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCE 3811
Query: 321 VQHPLGSQHLSFILSVQRSSS 341
+ +GS S + ++ S
Sbjct: 3812 AVNDVGSDSCSTEIVIKEPPS 3832
Score = 37.4 bits (85), Expect = 0.024
Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 6/74 (8%)
Query: 264 IQEGQSLFLACTVDSNPPASLSWFREGKALNPSQT------SMSGTLELPNIGAREGGEF 317
++ G S L C + +P + WFR L S +++ N+ + G+F
Sbjct: 5435 VKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDF 5494
Query: 318 TCRVQHPLGSQHLS 331
C Q+P GS S
Sbjct: 5495 ICEAQNPAGSTSCS 5508
Score = 37.0 bits (84), Expect = 0.031
Identities = 63/302 (20%), Positives = 105/302 (34%), Gaps = 67/302 (22%)
Query: 53 SPPLYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMED 112
S P+ + WF+D D+ + + +F L I D
Sbjct: 4701 SHPISIQWFKD---------------DQEISASEKYKFSF----HDNTAFLEISQLEGTD 4741
Query: 113 TGSYFFRVERGRDVKYSYQQNKLNLEVTA---LIEKPDIHFLEPLESGRPTRLSCSLPGS 169
+G+Y K + Q +L V +EKP + P +L + G+
Sbjct: 4742 SGTYTCSATN----KAGHNQCSGHLTVKEPPYFVEKPQSQDVNP---NTRVQLKALVGGT 4794
Query: 170 CEAGPPLTFSW--------TGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQ 221
P+T W +G A S +T+ S EL + D GT + CQ+
Sbjct: 4795 A----PMTIKWFKDNKELHSGAARSVWKDDTSTSLEL-FAAKATDSGTYI-CQLSNDVGT 4848
Query: 222 VTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPP 281
T++ T L V PQ F + + + ++ GQS C + P
Sbjct: 4849 ATSKAT--LFVKEPPQ------FIKKPSPVLV----------LRNGQSTTFECQITGTPK 4890
Query: 282 ASLSWFREGKALNPSQ----TSMSGTLELPNIGAR--EGGEFTCRVQHPLGSQHLSFILS 335
+SW+ +G + Q + + G GAR G + C ++ G+ S L
Sbjct: 4891 IRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELK 4950
Query: 336 VQ 337
V+
Sbjct: 4951 VK 4952
Score = 36.6 bits (83), Expect = 0.041
Identities = 60/291 (20%), Positives = 108/291 (37%), Gaps = 61/291 (20%)
Query: 102 SLSIGDARMEDTGSYFFRVER-GRDVKYSYQQNKLNLEVTALIEKPDIHFLEP---LESG 157
SL + + D+G+Y +V V+ S N E +EK LEP L+ G
Sbjct: 4262 SLELYLVKTSDSGTYTCKVSNVAGGVECS--ANLFVKEPATFVEK-----LEPSQLLKKG 4314
Query: 158 RPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSS--ELTLTPRPEDHGTN----L 211
T+L+C + G+ PP+ +W N + R S E T R D G
Sbjct: 4315 DATQLACKVTGT----PPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEY 4370
Query: 212 TCQVKRQ-GAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSL 270
C+ + + G+ + + Y + + + + +
Sbjct: 4371 MCEAQNEAGSDHCSSIVIVKESPYFTKEFK--------------------PIEVLKEYDV 4410
Query: 271 FLACTVDSNPPASLSWFREGKALNPSQTSMSG------TLELPNIGAREGGEFTCRVQHP 324
L V PP ++WF++ L + + +L++ A + GE+ CRV +
Sbjct: 4411 MLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNE 4470
Query: 325 LGS----------QHLSFILSVQRSSS---SCICVTEKQQGSWPLVLTLIR 362
+GS + SFI ++ +SS +GS P+ +T ++
Sbjct: 4471 VGSSICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLK 4521
Score = 36.6 bits (83), Expect = 0.041
Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
Query: 260 MSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNP------SQTSMSGTLELPNIGARE 313
+SV + G+S C V P ++W ++ + + P + + TL + +G +
Sbjct: 7219 VSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGD 7278
Query: 314 GGEFTCRVQHPLGSQHLSFILSVQ 337
G++TC + G S L VQ
Sbjct: 7279 AGQYTCYASNIAGKDSCSAQLGVQ 7302
Score = 36.6 bits (83), Expect = 0.041
Identities = 32/104 (30%), Positives = 46/104 (44%), Gaps = 28/104 (26%)
Query: 18 KPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVVATNN 77
+P +E +Q VT++EG + C FS P + WFR+G I
Sbjct: 8744 EPAWERHLQ-DVTLKEGQTCTMTCQFSVP--------NVKSEWFRNGRI----------- 8783
Query: 78 PDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVE 121
+KP QGR + +V+ K L+I D R ED G Y + E
Sbjct: 8784 ----LKP--QGRHKT--EVEHKVHKLTIADVRAEDQGQYTCKYE 8819
Score = 36.6 bits (83), Expect = 0.041
Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 6/79 (7%)
Query: 264 IQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSG------TLELPNIGAREGGEF 317
++ G ++ L TV P ++SW ++G L P++ TLEL ++ ++ G++
Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 19366
Query: 318 TCRVQHPLGSQHLSFILSV 336
T ++ GS+ + L V
Sbjct: 19367 TITAENSSGSKSATIKLKV 19385
Score = 36.2 bits (82), Expect = 0.053
Identities = 17/69 (24%), Positives = 36/69 (52%), Gaps = 6/69 (8%)
Query: 264 IQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ------TSMSGTLELPNIGAREGGEF 317
++ G+S+ L T P S++W ++G + S+ T + LE+ N R+ G++
Sbjct: 5997 VEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQY 6056
Query: 318 TCRVQHPLG 326
+C +++ G
Sbjct: 6057 SCEIENEAG 6065
Score = 36.2 bits (82), Expect = 0.053
Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 266 EGQSLFLACTVDSNPPASLSWF------REGKALNPSQTSMSGTLELPNIGAREGGEFTC 319
+G + L C + PP +SW+ R GK + ++ + N+ A + GE+ C
Sbjct: 7412 KGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQC 7471
Query: 320 RVQHPLGS 327
+ + +GS
Sbjct: 7472 KATNDVGS 7479
Score = 35.0 bits (79), Expect = 0.12
Identities = 55/245 (22%), Positives = 92/245 (37%), Gaps = 44/245 (17%)
Query: 97 QKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLES 156
+ K +L I A+++D+G+Y S E + ++K D +L +
Sbjct: 3695 EDKIATLEIPLAKLKDSGTYVCTASNEAGSS-SCSATVTVREPPSFVKKVDPSYL--MLP 3751
Query: 157 GRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTR----SSELTLT---PRPEDHGT 209
G RL C L GS P + +W N + T R +SE L + ED G+
Sbjct: 3752 GESARLHCKLKGS----PVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGS 3807
Query: 210 NLTCQVKRQGAQ-VTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQ 268
V G+ +TE ++ S+ + I G
Sbjct: 3808 YSCEAVNDVGSDSCSTEIVIKEPPSF---------------------IKTLEPADIVRGT 3846
Query: 269 SLFLACTVDSNPPASLSWFREGKALNP-------SQTSMSGTLELPNIGAREGGEFTCRV 321
+ L C V P +SWF++ K + SQ S+ LE+ + + + GE+ C V
Sbjct: 3847 NALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLV-CLEIFSFNSADVGEYECVV 3905
Query: 322 QHPLG 326
+ +G
Sbjct: 3906 ANEVG 3910
Score = 35.0 bits (79), Expect = 0.12
Identities = 27/108 (25%), Positives = 45/108 (41%), Gaps = 6/108 (5%)
Query: 236 PQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKAL-- 293
P+ A+SI + +G A I V + G++ L+C + P + W+R GK L
Sbjct: 30516 PRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ 30575
Query: 294 ----NPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ 337
S + TL + + G +TC + +G S L +Q
Sbjct: 30576 SRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 30623
Score = 34.7 bits (78), Expect = 0.15
Identities = 56/260 (21%), Positives = 95/260 (36%), Gaps = 54/260 (20%)
Query: 103 LSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDI--HFLEPLES---- 156
L A + D+G Y F + S + + E T + DI F +PL +
Sbjct: 4074 LKFYSAELHDSGQYTFEI--------SNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSV 4125
Query: 157 -GRPTRLSCSLPGSCEAGPPLTFSW--TGNALSPLDP------ETTRSSELTLTPRPEDH 207
RL C + GS P+ SW G ++ D E T S E+ D
Sbjct: 4126 VNGTCRLDCKIAGSL----PMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDM-NDA 4180
Query: 208 GTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEG 267
G N TC+ + + + L V P ++ S + G
Sbjct: 4181 G-NFTCRATNSVG--SKDSSGALIVQEPPS-----------------FVTKPGSKDVLPG 4220
Query: 268 QSLFLACTVDSNPPASLSWFREGKALNP------SQTSMSGTLELPNIGAREGGEFTCRV 321
++ L T + P ++ WF+ K L ++ ++ +LEL + + G +TC+V
Sbjct: 4221 SAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKV 4280
Query: 322 QHPLGSQHLSFILSVQRSSS 341
+ G S L V+ ++
Sbjct: 4281 SNVAGGVECSANLFVKEPAT 4300
Score = 34.7 bits (78), Expect = 0.15
Identities = 62/306 (20%), Positives = 102/306 (33%), Gaps = 65/306 (21%)
Query: 53 SPPLYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMED 112
+P L V W++DG++ + + +F + SL I +D
Sbjct: 5730 TPELSVEWYKDGKL---------------LTSSQKHKFSFYNKIS----SLRILSVERQD 5770
Query: 113 TGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDI----HFLEPLES-GRPTRLSCSLP 167
G+Y F+V Q N TA+++ D F L++ G SC L
Sbjct: 5771 AGTYTFQV----------QNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILE 5820
Query: 168 GSCEAGPPLTFSW---TGNALSPLDPETTRSSE---LTLTPRPEDHGTNLTCQVKRQGAQ 221
P++ +W +S +TT S L L N TC
Sbjct: 5821 CKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAG- 5879
Query: 222 VTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPP 281
+ E L V P + + + G+++ + PP
Sbjct: 5880 -SDECRAVLTVQEPPS-----------------FVKEPEPLEVLPGKNVTFTSVIRGTPP 5921
Query: 282 ASLSWFR------EGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILS 335
++WFR +G N LEL NI + GE+TC V + G + L
Sbjct: 5922 FKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLF 5981
Query: 336 VQRSSS 341
V+ ++
Sbjct: 5982 VKEPAA 5987
Score = 34.7 bits (78), Expect = 0.15
Identities = 18/74 (24%), Positives = 35/74 (47%), Gaps = 6/74 (8%)
Query: 256 LSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALN-PSQTSMSG-----TLELPNI 309
+S S I EGQ++ C + P + WF+ ++ S S+S +LE+ N
Sbjct: 33137 ISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNA 33196
Query: 310 GAREGGEFTCRVQH 323
+ G++T + ++
Sbjct: 33197 SVSDSGKYTIKAKN 33210
Score = 34.3 bits (77), Expect = 0.20
Identities = 59/267 (22%), Positives = 99/267 (37%), Gaps = 47/267 (17%)
Query: 96 VQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEP-- 153
V+++ + I + R D G Y F R R + + L V A + L+P
Sbjct: 3198 VERRIHRMFISETRQSDAGEYTFVAGRNR--------SSVTLYVNAPEPPQVLQELQPVT 3249
Query: 154 LESGRPTRLSCSLPGSCEAGPPLTFSW--------TGNALSPLDPETTRSSELTLTPRPE 205
++SG+P R + G P SW TG L + + L + PE
Sbjct: 3250 VQSGKPARFCAVISGR----PQPKISWYKEEQLLSTGFKCKFLH-DGQEYTLLLIEAFPE 3304
Query: 206 DHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQ 265
D TC+ K TT ++ + V P+ ++ + + + P+Q
Sbjct: 3305 DAAV-YTCEAKNDYGVATTSASLSVEV---PEVVS--------PDQEMPVYPPAIITPLQ 3352
Query: 266 -----EGQSLFLACTVDSNPPASLSWFREGKALNPSQ----TSMSGT--LELPNIGAREG 314
EGQ C V S +SW+ + K + PS+ T T LE+ +
Sbjct: 3353 DTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDE 3411
Query: 315 GEFTCRVQHPLGSQHLSFILSVQRSSS 341
G +T + +G + LS++ S
Sbjct: 3412 GTYTFVASNAVGQVSSTANLSLEAPES 3438
Score = 34.3 bits (77), Expect = 0.20
Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 267 GQSLFLACTVDSNPPASLSWF------REGKALNPSQTSMSGTLELPNIGAREGGEFTCR 320
GQ++ L V + P S++W RE + S ++ L +P++ GG++TC
Sbjct: 3938 GQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCL 3997
Query: 321 VQHPLGSQ 328
++ GSQ
Sbjct: 3998 AENEAGSQ 4005
Score = 34.3 bits (77), Expect = 0.20
Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
Query: 266 EGQSLFLACTVDSNPPASLSWFREGKALNPSQT------SMSGTLELPNIGAREGGEFTC 319
+G + L C V + P S+ WF++ + ++ S+ + LE+ + + G +TC
Sbjct: 4688 KGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTC 4747
Query: 320 RVQHPLGSQHLSFILSVQ 337
+ G S L+V+
Sbjct: 4748 SATNKAGHNQCSGHLTVK 4765
Score = 34.3 bits (77), Expect = 0.20
Identities = 61/289 (21%), Positives = 111/289 (38%), Gaps = 57/289 (19%)
Query: 102 SLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNL-EVTALIEKPDIHFLEPLESGRPT 160
SL + A+ D+G+Y ++ DV + + L + E I+KP + L +G+ T
Sbjct: 4824 SLELFAAKATDSGTYICQLSN--DVGTATSKATLFVKEPPQFIKKPSPVLV--LRNGQST 4879
Query: 161 RLSCSLPGSCEAGPPLTFSW--TGNALSPLDPETTRSSELTLT-----PRPEDHGTNLTC 213
C + G+ P + SW GN ++ + + T R E+ GT + C
Sbjct: 4880 TFECQITGT----PKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYV-C 4934
Query: 214 QVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLA 273
+ + T +++L V P T +R L V + + + L
Sbjct: 4935 EARNDAG--TASCSIELKVKEPP--------------TFIRELK---PVEVVKYSDVELE 4975
Query: 274 CTVDSNPPASLSWFREGKALNPS-----------------QTSMSGTLELPNIGAREGGE 316
C V PP ++W + + + S + S T E I + EGG
Sbjct: 4976 CEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGS 5035
Query: 317 FTCRVQHPLGSQHLSFILSVQRSSS---SCICVTEKQQGSWPLVLTLIR 362
+C + L + SFI ++ +++ S GS P+ +T ++
Sbjct: 5036 CSCSTRVAL-KEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLK 5083
Score = 34.3 bits (77), Expect = 0.20
Identities = 20/77 (25%), Positives = 35/77 (45%), Gaps = 7/77 (9%)
Query: 267 GQSLFLACTVDSNPPASLSWF-------REGKALNPSQTSMSGTLELPNIGAREGGEFTC 319
G+ + L T++ P S+ WF RE + S + TL+ + G++TC
Sbjct: 7506 GKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTC 7565
Query: 320 RVQHPLGSQHLSFILSV 336
++++ G Q LSV
Sbjct: 7566 QIKNDAGMQECFATLSV 7582
Score = 34.3 bits (77), Expect = 0.20
Identities = 21/94 (22%), Positives = 41/94 (43%), Gaps = 4/94 (4%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKALNP----SQTSMSGTLELPNIGAREGGE 316
+V I+ G SL L +V PP ++W ++G L T L + + + G+
Sbjct: 29455 TVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGK 29514
Query: 317 FTCRVQHPLGSQHLSFILSVQRSSSSCICVTEKQ 350
+T ++ G + + ++ V + C V K+
Sbjct: 29515 YTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKE 29548
Score = 33.9 bits (76), Expect = 0.26
Identities = 18/67 (26%), Positives = 32/67 (47%), Gaps = 7/67 (10%)
Query: 262 VPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGT------LELPNIGAREGG 315
V ++EGQ+ + C S P WFR G+ L P + L + ++ A + G
Sbjct: 8754 VTLKEGQTCTMTCQF-SVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQG 8812
Query: 316 EFTCRVQ 322
++TC+ +
Sbjct: 8813 QYTCKYE 8819
Score = 33.5 bits (75), Expect = 0.34
Identities = 17/77 (22%), Positives = 36/77 (46%), Gaps = 6/77 (7%)
Query: 267 GQSLFLACTVDSNPPASLSWFREGKALNPSQT------SMSGTLELPNIGAREGGEFTCR 320
G+ L C VD P +SW++E L + + +L + + + GE++C+
Sbjct: 7034 GEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCK 7093
Query: 321 VQHPLGSQHLSFILSVQ 337
+ +G+ S +L ++
Sbjct: 7094 ADNSVGAVASSAVLVIK 7110
Score = 33.1 bits (74), Expect = 0.45
Identities = 14/62 (22%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 272 LACTVDSNPPASLSWFREGKALNPSQT------SMSGTLELPNIGAREGGEFTCRVQHPL 325
L C + PP + W+++ + L S+ + ++ + N+ + GE+ C+ Q+ +
Sbjct: 5536 LECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEV 5595
Query: 326 GS 327
GS
Sbjct: 5596 GS 5597
Score = 33.1 bits (74), Expect = 0.45
Identities = 17/79 (21%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Query: 264 IQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ------TSMSGTLELPNIGAREGGEF 317
++ G + L T PP S+SW ++ ++ S+ T S LE+ + ++
Sbjct: 6938 VETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQY 6997
Query: 318 TCRVQHPLGSQHLSFILSV 336
+C +++ G ++SV
Sbjct: 6998 SCLIENEAGQDICEALVSV 7016
Score = 32.7 bits (73), Expect = 0.59
Identities = 40/193 (20%), Positives = 66/193 (34%), Gaps = 19/193 (9%)
Query: 157 GRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPR-------PEDHGT 209
G+P R C + G+ L SW R ++ T + PED GT
Sbjct: 3359 GQPARFQCRVSGT-----DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGT 3413
Query: 210 NLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQS 269
T QV++ + L + + I A I + + G
Sbjct: 3414 -YTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHL 3472
Query: 270 LFLACTVDSNPPASLSWFREGKALNPSQ------TSMSGTLELPNIGAREGGEFTCRVQH 323
C + S P WF+ G+ + S + +LE+ + GE+TC+ +
Sbjct: 3473 AKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASN 3532
Query: 324 PLGSQHLSFILSV 336
GS + L+V
Sbjct: 3533 EYGSVSCTATLTV 3545
Score = 32.3 bits (72), Expect = 0.77
Identities = 15/70 (21%), Positives = 29/70 (41%), Gaps = 6/70 (8%)
Query: 274 CTVDSNPPASLSWFREGKALNPSQ------TSMSGTLELPNIGAREGGEFTCRVQHPLGS 327
C + +P + W+++ + S LE+ N+ + G++TC + GS
Sbjct: 7327 CKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGS 7386
Query: 328 QHLSFILSVQ 337
S L V+
Sbjct: 7387 ASSSTSLKVK 7396
Score = 32.0 bits (71), Expect = 1.0
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 6/77 (7%)
Query: 266 EGQSLFLACTVDSNPPASLSWFREGKALNPS------QTSMSGTLELPNIGAREGGEFTC 319
EG+ L + + P ++SW ++GK + S +S LE+P + G +T
Sbjct: 14400 EGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTI 14459
Query: 320 RVQHPLGSQHLSFILSV 336
+++ LGS S + V
Sbjct: 14460 TLENKLGSATASINVKV 14476
Score = 31.6 bits (70), Expect = 1.3
Identities = 31/147 (21%), Positives = 54/147 (36%), Gaps = 17/147 (11%)
Query: 208 GTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFF---RNGTGTAL--------RIL 256
G + QV+ + V R ++ +S Q+ A F RN + L ++L
Sbjct: 3183 GIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVL 3242
Query: 257 SNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPS------QTSMSGTLELPNIG 310
V +Q G+ + P +SW++E + L+ TL L
Sbjct: 3243 QELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAF 3302
Query: 311 AREGGEFTCRVQHPLGSQHLSFILSVQ 337
+ +TC ++ G S LSV+
Sbjct: 3303 PEDAAVYTCEAKNDYGVATTSASLSVE 3329
Score = 31.6 bits (70), Expect = 1.3
Identities = 61/333 (18%), Positives = 119/333 (35%), Gaps = 60/333 (18%)
Query: 15 LQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVVA 74
L ++P ++ KSV V E + + C + +P L V W +DG
Sbjct: 5136 LVQEPAQIVEKAKSVDVTEKDPMTLECVVA-------GTPELKVKWLKDG---------- 5178
Query: 75 TNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNK 134
+++ P +V S I +D+G Y F+VE + +
Sbjct: 5179 -----KQIVPSRYFSMSFENNV----ASFRIQSVMKQDSGQYTFKVEN------DFGSSS 5223
Query: 135 LNLEVTALIEKPDIHFLEPLES-----GRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLD 189
+ + L + F + L G + C + GS P++ W +
Sbjct: 5224 CDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSL----PISAQWFKDG----- 5274
Query: 190 PETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGT 249
E + S++ L H +++ +V + T T +++ + A + I
Sbjct: 5275 KEISTSAKYRLVC----HERSVSLEVNNLELEDTANYTCKVS-NVAGDDACSGILTVKEP 5329
Query: 250 GTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGT------ 303
+ L ++P ++ + PP + WF++ L G
Sbjct: 5330 PSFLVKPGRQQAIP---DSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSF 5386
Query: 304 LELPNIGAREGGEFTCRVQHPLGSQHLSFILSV 336
L L ++ A + G++TC V + +GS + +L V
Sbjct: 5387 LNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLV 5419
Score = 31.6 bits (70), Expect = 1.3
Identities = 18/68 (26%), Positives = 33/68 (48%), Gaps = 6/68 (8%)
Query: 266 EGQSLFLACTVDSNPPASLSWFREGKALNPSQ----TSMSGT--LELPNIGAREGGEFTC 319
EG S L V + P +++W++ + P+ T + T L++ G + G +TC
Sbjct: 8263 EGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTC 8322
Query: 320 RVQHPLGS 327
+V + GS
Sbjct: 8323 KVSNDAGS 8330
Score = 31.2 bits (69), Expect = 1.7
Identities = 27/128 (21%), Positives = 53/128 (41%), Gaps = 17/128 (13%)
Query: 174 PPLTFSWTGNALSPLDPETTRSSE-------LTLTPRPEDHGTNLTCQVKRQGAQVTTER 226
P +T+ +G + P D + + E LT+ D T + + + + +
Sbjct: 31719 PHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKA 31778
Query: 227 TVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSW 286
+ + + P + + F+ R+L+N QEGQS+ V PP +L W
Sbjct: 31779 KLTVTLHPPPTDSTLRPMFK-------RLLANA---ECQEGQSVCFEIRVSGIPPPTLKW 31828
Query: 287 FREGKALN 294
++G+ L+
Sbjct: 31829 EKDGQPLS 31836
Score = 30.8 bits (68), Expect = 2.2
Identities = 18/72 (25%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 264 IQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ----TSMSGTLELPNIGAREGGEFTC 319
I+ G +L L+ + P ++W +E + T + LE+ N +GG ++
Sbjct: 17230 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSL 17289
Query: 320 RVQHPLGSQHLS 331
V++P GS+ +S
Sbjct: 17290 TVENPAGSKTVS 17301
Score = 30.4 bits (67), Expect = 2.9
Identities = 64/347 (18%), Positives = 115/347 (33%), Gaps = 89/347 (25%)
Query: 18 KPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVVATNN 77
+P Y ++ + V V G + C + +P + V W++
Sbjct: 7959 EPPYFVKQLEPVKVSVGDSASLQCQLA-------GTPEIGVSWYKG-------------- 7997
Query: 78 PDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNL 137
D +++P T + +V +L + D+G Y + E S + +
Sbjct: 7998 -DTKLRPTTTYKMHFRNNV----ATLVFNQVDINDSGEYICKAEN------SVGEVSAST 8046
Query: 138 EVTALIEKPDIHFLEPLES-----GRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPET 192
+T +K F L G P C++ GS P++ SW + D
Sbjct: 8047 FLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGS----EPISVSWYKDGKPLKDSPN 8102
Query: 193 TRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLA--ISIFFRNGTG 250
++S L + T LN+ ++LA S N G
Sbjct: 8103 VQTSFL--------------------------DNTATLNIFKTDRSLAGQYSCTATNPIG 8136
Query: 251 TALR----ILSNGMSVPIQE----------GQSLFLACTVDSNPPASLSW------FREG 290
+A IL+ G + P + G+S C V P +SW R G
Sbjct: 8137 SASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSG 8196
Query: 291 KALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ 337
S S L + + + G++TC + +G + L+++
Sbjct: 8197 GKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIK 8243
Score = 30.4 bits (67), Expect = 2.9
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 7/72 (9%)
Query: 264 IQEGQSLFL-ACTVDSNPPASLSWFREGKALNPSQ------TSMSGTLELPNIGAREGGE 316
I+ G ++ L A ++ P SW + GK + PS T S L + ++ GE
Sbjct: 20390 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 20449
Query: 317 FTCRVQHPLGSQ 328
+T +P G++
Sbjct: 20450 YTITATNPFGTK 20461
Score = 30.4 bits (67), Expect = 2.9
Identities = 17/77 (22%), Positives = 39/77 (50%), Gaps = 6/77 (7%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKAL-NPSQTSMSGTLELPNIGARE-----G 314
S +Q GQ L + + P +++W ++G L ++ +++ +L+L + +E G
Sbjct: 23238 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDG 23297
Query: 315 GEFTCRVQHPLGSQHLS 331
G++ V + +G + S
Sbjct: 23298 GQYGITVANVVGQKTAS 23314
Score = 29.6 bits (65), Expect = 5.0
Identities = 17/74 (22%), Positives = 34/74 (45%), Gaps = 8/74 (10%)
Query: 262 VPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ--------TSMSGTLELPNIGARE 313
+ I EG+ L +AC P ++W G+ ++ + T TL + ++ ++
Sbjct: 33338 ISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQD 33397
Query: 314 GGEFTCRVQHPLGS 327
GG +T + + GS
Sbjct: 33398 GGLYTLSLGNEFGS 33411
Score = 28.9 bits (63), Expect = 8.5
Identities = 17/84 (20%), Positives = 40/84 (47%), Gaps = 7/84 (8%)
Query: 264 IQEGQSLFLACTVDSNPPASLSWFREGKALNPSQT------SMSGTLELPNIGAREGGEF 317
++ G + F A T+ + P +++W ++ + + +L L I + G++
Sbjct: 4498 LRGGTAAFQA-TLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKY 4556
Query: 318 TCRVQHPLGSQHLSFILSVQRSSS 341
C+ ++ G Q S +LSV+ ++
Sbjct: 4557 VCQAKNDAGIQRCSALLSVKEPAT 4580
Score = 28.9 bits (63), Expect = 8.5
Identities = 17/72 (23%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ------TSMSGTLELPNIGAREG 314
+V ++ G++ L V PP ++ W ++GK L + S L + R+
Sbjct: 21470 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDS 21529
Query: 315 GEFTCRVQHPLG 326
G +T +P G
Sbjct: 21530 GAYTLTATNPGG 21541
Score = 28.9 bits (63), Expect = 8.5
Identities = 17/73 (23%), Positives = 32/73 (43%), Gaps = 6/73 (8%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGT------LELPNIGAREG 314
++ + G+ + L + PP + SWF G L S+ T L + R+
Sbjct: 29747 TIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDT 29806
Query: 315 GEFTCRVQHPLGS 327
GE+T +++ G+
Sbjct: 29807 GEYTLELKNVTGT 29819
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 57.4 bits (137), Expect = 2e-08
Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 11/115 (9%)
Query: 249 TGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPS------QTSMSG 302
T A RIL+ S+ + EG+S +C D P +++W R+G+ L+ S T
Sbjct: 26252 TTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKS 26311
Query: 303 TLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSSSCICVTEKQQGSWPLV 357
T E+ ++ A + G ++ V++ G Q F L++Q++ VTEK S P V
Sbjct: 26312 TFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR-----VTEKAVTSPPRV 26361
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 9/104 (8%)
Query: 255 ILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPS----QTSMSG--TLELPN 308
++S +V + EG+S+ L C + P +++W+RE + S T SG L +
Sbjct: 899 LVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIRE 958
Query: 309 IGAREGGEFTCRVQHPLGSQHLSFILSVQRS---SSSCICVTEK 349
A + G FTC + G+ S L+VQ S VTEK
Sbjct: 959 AFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEK 1002
Score = 36.6 bits (83), Expect = 0.041
Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 6/79 (7%)
Query: 264 IQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSG------TLELPNIGAREGGEF 317
++ G ++ L TV P ++SW ++G L P++ TLEL ++ ++ G++
Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 13061
Query: 318 TCRVQHPLGSQHLSFILSV 336
T ++ GS+ + L V
Sbjct: 13062 TITAENSSGSKSATIKLKV 13080
Score = 35.8 bits (81), Expect = 0.069
Identities = 54/278 (19%), Positives = 107/278 (38%), Gaps = 26/278 (9%)
Query: 73 VATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQ 132
V+ + D+++KP R D + L I +A ED G+Y F V
Sbjct: 3329 VSWYSKDKKIKPSRFFRMTQFEDTYQ----LEIAEAYPEDEGTYTFVASNA--VGQVSST 3382
Query: 133 NKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPET 192
L+LEV AL + SG+ R S ++ +F+ + +S + ++
Sbjct: 3383 ANLSLEVQALDRQ---------SSGKDVRESAKSQAVADS----SFTKEESKISQKEIKS 3429
Query: 193 TRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTA 252
+ S + + + + T L+ L+ + TG A
Sbjct: 3430 FQGSSYEYEVQVFESVSQSSIHTAASVQDTQLCHTASLSQIAESTELSKECA-KESTGEA 3488
Query: 253 LRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQT---SMSGTLE---L 306
+I + V ++ G + C + + ++W EG + S+ S +G ++ +
Sbjct: 3489 PKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTI 3548
Query: 307 PNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSSSCI 344
N+ + G ++C V + G + S +LSV+ + S +
Sbjct: 3549 CNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESIL 3586
Score = 35.0 bits (79), Expect = 0.12
Identities = 27/108 (25%), Positives = 45/108 (41%), Gaps = 6/108 (5%)
Query: 236 PQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKAL-- 293
P+ A+SI + +G A I V + G++ L+C + P + W+R GK L
Sbjct: 24211 PRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ 24270
Query: 294 ----NPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ 337
S + TL + + G +TC + +G S L +Q
Sbjct: 24271 SRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24318
Score = 34.7 bits (78), Expect = 0.15
Identities = 18/74 (24%), Positives = 35/74 (47%), Gaps = 6/74 (8%)
Query: 256 LSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALN-PSQTSMSG-----TLELPNI 309
+S S I EGQ++ C + P + WF+ ++ S S+S +LE+ N
Sbjct: 26832 ISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNA 26891
Query: 310 GAREGGEFTCRVQH 323
+ G++T + ++
Sbjct: 26892 SVSDSGKYTIKAKN 26905
Score = 34.3 bits (77), Expect = 0.20
Identities = 21/94 (22%), Positives = 41/94 (43%), Gaps = 4/94 (4%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKALNP----SQTSMSGTLELPNIGAREGGE 316
+V I+ G SL L +V PP ++W ++G L T L + + + G+
Sbjct: 23150 TVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGK 23209
Query: 317 FTCRVQHPLGSQHLSFILSVQRSSSSCICVTEKQ 350
+T ++ G + + ++ V + C V K+
Sbjct: 23210 YTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKE 23243
Score = 33.5 bits (75), Expect = 0.34
Identities = 58/263 (22%), Positives = 98/263 (37%), Gaps = 47/263 (17%)
Query: 96 VQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEP-- 153
V+++ + I + R D G Y F R R + + L V A + L+P
Sbjct: 3152 VERRIHRMFISETRQSDAGEYTFVAGRNR--------SSVTLYVNAPEPPQVLQELQPVT 3203
Query: 154 LESGRPTRLSCSLPGSCEAGPPLTFSW--------TGNALSPLDPETTRSSELTLTPRPE 205
++SG+P R + G P SW TG L + + L + PE
Sbjct: 3204 VQSGKPARFCAVISGR----PQPKISWYKEEQLLSTGFKCKFLH-DGQEYTLLLIEAFPE 3258
Query: 206 DHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQ 265
D TC+ K TT ++ + V P+ ++ + + + P+Q
Sbjct: 3259 DAAV-YTCEAKNDYGVATTSASLSVEV---PEVVS--------PDQEMPVYPPAIITPLQ 3306
Query: 266 -----EGQSLFLACTVDSNPPASLSWFREGKALNPSQ----TSMSGT--LELPNIGAREG 314
EGQ C V S +SW+ + K + PS+ T T LE+ +
Sbjct: 3307 DTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDE 3365
Query: 315 GEFTCRVQHPLGSQHLSFILSVQ 337
G +T + +G + LS++
Sbjct: 3366 GTYTFVASNAVGQVSSTANLSLE 3388
Score = 32.0 bits (71), Expect = 1.0
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 6/77 (7%)
Query: 266 EGQSLFLACTVDSNPPASLSWFREGKALNPS------QTSMSGTLELPNIGAREGGEFTC 319
EG+ L + + P ++SW ++GK + S +S LE+P + G +T
Sbjct: 8095 EGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTI 8154
Query: 320 RVQHPLGSQHLSFILSV 336
+++ LGS S + V
Sbjct: 8155 TLENKLGSATASINVKV 8171
Score = 31.6 bits (70), Expect = 1.3
Identities = 31/147 (21%), Positives = 54/147 (36%), Gaps = 17/147 (11%)
Query: 208 GTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFF---RNGTGTAL--------RIL 256
G + QV+ + V R ++ +S Q+ A F RN + L ++L
Sbjct: 3137 GIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVL 3196
Query: 257 SNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPS------QTSMSGTLELPNIG 310
V +Q G+ + P +SW++E + L+ TL L
Sbjct: 3197 QELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAF 3256
Query: 311 AREGGEFTCRVQHPLGSQHLSFILSVQ 337
+ +TC ++ G S LSV+
Sbjct: 3257 PEDAAVYTCEAKNDYGVATTSASLSVE 3283
Score = 31.6 bits (70), Expect = 1.3
Identities = 17/69 (24%), Positives = 30/69 (43%), Gaps = 6/69 (8%)
Query: 274 CTVDSNPPASLSWFREGKALNPS------QTSMSGTLELPNIGAREGGEFTCRVQHPLGS 327
C + S P WF+ G+ + S + +LE+ + GE+TC+ + GS
Sbjct: 4550 CEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGS 4609
Query: 328 QHLSFILSV 336
+ L+V
Sbjct: 4610 VSCTATLTV 4618
Score = 31.2 bits (69), Expect = 1.7
Identities = 27/128 (21%), Positives = 53/128 (41%), Gaps = 17/128 (13%)
Query: 174 PPLTFSWTGNALSPLDPETTRSSE-------LTLTPRPEDHGTNLTCQVKRQGAQVTTER 226
P +T+ +G + P D + + E LT+ D T + + + + +
Sbjct: 25414 PHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKA 25473
Query: 227 TVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSW 286
+ + + P + + F+ R+L+N QEGQS+ V PP +L W
Sbjct: 25474 KLTVTLHPPPTDSTLRPMFK-------RLLANA---ECQEGQSVCFEIRVSGIPPPTLKW 25523
Query: 287 FREGKALN 294
++G+ L+
Sbjct: 25524 EKDGQPLS 25531
Score = 30.8 bits (68), Expect = 2.2
Identities = 18/72 (25%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 264 IQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ----TSMSGTLELPNIGAREGGEFTC 319
I+ G +L L+ + P ++W +E + T + LE+ N +GG ++
Sbjct: 10925 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSL 10984
Query: 320 RVQHPLGSQHLS 331
V++P GS+ +S
Sbjct: 10985 TVENPAGSKTVS 10996
Score = 30.4 bits (67), Expect = 2.9
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 7/72 (9%)
Query: 264 IQEGQSLFL-ACTVDSNPPASLSWFREGKALNPSQ------TSMSGTLELPNIGAREGGE 316
I+ G ++ L A ++ P SW + GK + PS T S L + ++ GE
Sbjct: 14085 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 14144
Query: 317 FTCRVQHPLGSQ 328
+T +P G++
Sbjct: 14145 YTITATNPFGTK 14156
Score = 30.4 bits (67), Expect = 2.9
Identities = 17/77 (22%), Positives = 39/77 (50%), Gaps = 6/77 (7%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKAL-NPSQTSMSGTLELPNIGARE-----G 314
S +Q GQ L + + P +++W ++G L ++ +++ +L+L + +E G
Sbjct: 16933 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDG 16992
Query: 315 GEFTCRVQHPLGSQHLS 331
G++ V + +G + S
Sbjct: 16993 GQYGITVANVVGQKTAS 17009
Score = 29.6 bits (65), Expect = 5.0
Identities = 17/74 (22%), Positives = 34/74 (45%), Gaps = 8/74 (10%)
Query: 262 VPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ--------TSMSGTLELPNIGARE 313
+ I EG+ L +AC P ++W G+ ++ + T TL + ++ ++
Sbjct: 27033 ISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQD 27092
Query: 314 GGEFTCRVQHPLGS 327
GG +T + + GS
Sbjct: 27093 GGLYTLSLGNEFGS 27106
Score = 28.9 bits (63), Expect = 8.5
Identities = 17/72 (23%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ------TSMSGTLELPNIGAREG 314
+V ++ G++ L V PP ++ W ++GK L + S L + R+
Sbjct: 15165 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDS 15224
Query: 315 GEFTCRVQHPLG 326
G +T +P G
Sbjct: 15225 GAYTLTATNPGG 15236
Score = 28.9 bits (63), Expect = 8.5
Identities = 17/73 (23%), Positives = 32/73 (43%), Gaps = 6/73 (8%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGT------LELPNIGAREG 314
++ + G+ + L + PP + SWF G L S+ T L + R+
Sbjct: 23442 TIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDT 23501
Query: 315 GEFTCRVQHPLGS 327
GE+T +++ G+
Sbjct: 23502 GEYTLELKNVTGT 23514
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 57.4 bits (137), Expect = 2e-08
Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 11/115 (9%)
Query: 249 TGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPS------QTSMSG 302
T A RIL+ S+ + EG+S +C D P +++W R+G+ L+ S T
Sbjct: 26185 TTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKS 26244
Query: 303 TLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSSSCICVTEKQQGSWPLV 357
T E+ ++ A + G ++ V++ G Q F L++Q++ VTEK S P V
Sbjct: 26245 TFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR-----VTEKAVTSPPRV 26294
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 9/104 (8%)
Query: 255 ILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPS----QTSMSG--TLELPN 308
++S +V + EG+S+ L C + P +++W+RE + S T SG L +
Sbjct: 899 LVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIRE 958
Query: 309 IGAREGGEFTCRVQHPLGSQHLSFILSVQRS---SSSCICVTEK 349
A + G FTC + G+ S L+VQ S VTEK
Sbjct: 959 AFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEK 1002
Score = 36.6 bits (83), Expect = 0.041
Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 6/79 (7%)
Query: 264 IQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSG------TLELPNIGAREGGEF 317
++ G ++ L TV P ++SW ++G L P++ TLEL ++ ++ G++
Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12994
Query: 318 TCRVQHPLGSQHLSFILSV 336
T ++ GS+ + L V
Sbjct: 12995 TITAENSSGSKSATIKLKV 13013
Score = 35.0 bits (79), Expect = 0.12
Identities = 27/108 (25%), Positives = 45/108 (41%), Gaps = 6/108 (5%)
Query: 236 PQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKAL-- 293
P+ A+SI + +G A I V + G++ L+C + P + W+R GK L
Sbjct: 24144 PRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ 24203
Query: 294 ----NPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ 337
S + TL + + G +TC + +G S L +Q
Sbjct: 24204 SRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24251
Score = 34.7 bits (78), Expect = 0.15
Identities = 18/74 (24%), Positives = 35/74 (47%), Gaps = 6/74 (8%)
Query: 256 LSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALN-PSQTSMSG-----TLELPNI 309
+S S I EGQ++ C + P + WF+ ++ S S+S +LE+ N
Sbjct: 26765 ISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNA 26824
Query: 310 GAREGGEFTCRVQH 323
+ G++T + ++
Sbjct: 26825 SVSDSGKYTIKAKN 26838
Score = 34.3 bits (77), Expect = 0.20
Identities = 21/94 (22%), Positives = 41/94 (43%), Gaps = 4/94 (4%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKALNP----SQTSMSGTLELPNIGAREGGE 316
+V I+ G SL L +V PP ++W ++G L T L + + + G+
Sbjct: 23083 TVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGK 23142
Query: 317 FTCRVQHPLGSQHLSFILSVQRSSSSCICVTEKQ 350
+T ++ G + + ++ V + C V K+
Sbjct: 23143 YTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKE 23176
Score = 33.5 bits (75), Expect = 0.34
Identities = 58/263 (22%), Positives = 98/263 (37%), Gaps = 47/263 (17%)
Query: 96 VQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEP-- 153
V+++ + I + R D G Y F R R + + L V A + L+P
Sbjct: 3152 VERRIHRMFISETRQSDAGEYTFVAGRNR--------SSVTLYVNAPEPPQVLQELQPVT 3203
Query: 154 LESGRPTRLSCSLPGSCEAGPPLTFSW--------TGNALSPLDPETTRSSELTLTPRPE 205
++SG+P R + G P SW TG L + + L + PE
Sbjct: 3204 VQSGKPARFCAVISGR----PQPKISWYKEEQLLSTGFKCKFLH-DGQEYTLLLIEAFPE 3258
Query: 206 DHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQ 265
D TC+ K TT ++ + V P+ ++ + + + P+Q
Sbjct: 3259 DAAV-YTCEAKNDYGVATTSASLSVEV---PEVVS--------PDQEMPVYPPAIITPLQ 3306
Query: 266 -----EGQSLFLACTVDSNPPASLSWFREGKALNPSQ----TSMSGT--LELPNIGAREG 314
EGQ C V S +SW+ + K + PS+ T T LE+ +
Sbjct: 3307 DTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDE 3365
Query: 315 GEFTCRVQHPLGSQHLSFILSVQ 337
G +T + +G + LS++
Sbjct: 3366 GTYTFVASNAVGQVSSTANLSLE 3388
Score = 32.0 bits (71), Expect = 1.0
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 6/77 (7%)
Query: 266 EGQSLFLACTVDSNPPASLSWFREGKALNPS------QTSMSGTLELPNIGAREGGEFTC 319
EG+ L + + P ++SW ++GK + S +S LE+P + G +T
Sbjct: 8028 EGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTI 8087
Query: 320 RVQHPLGSQHLSFILSV 336
+++ LGS S + V
Sbjct: 8088 TLENKLGSATASINVKV 8104
Score = 31.6 bits (70), Expect = 1.3
Identities = 31/147 (21%), Positives = 54/147 (36%), Gaps = 17/147 (11%)
Query: 208 GTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFF---RNGTGTAL--------RIL 256
G + QV+ + V R ++ +S Q+ A F RN + L ++L
Sbjct: 3137 GIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVL 3196
Query: 257 SNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPS------QTSMSGTLELPNIG 310
V +Q G+ + P +SW++E + L+ TL L
Sbjct: 3197 QELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAF 3256
Query: 311 AREGGEFTCRVQHPLGSQHLSFILSVQ 337
+ +TC ++ G S LSV+
Sbjct: 3257 PEDAAVYTCEAKNDYGVATTSASLSVE 3283
Score = 31.6 bits (70), Expect = 1.3
Identities = 17/69 (24%), Positives = 30/69 (43%), Gaps = 6/69 (8%)
Query: 274 CTVDSNPPASLSWFREGKALNPS------QTSMSGTLELPNIGAREGGEFTCRVQHPLGS 327
C + S P WF+ G+ + S + +LE+ + GE+TC+ + GS
Sbjct: 4483 CEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGS 4542
Query: 328 QHLSFILSV 336
+ L+V
Sbjct: 4543 VSCTATLTV 4551
Score = 31.2 bits (69), Expect = 1.7
Identities = 27/128 (21%), Positives = 53/128 (41%), Gaps = 17/128 (13%)
Query: 174 PPLTFSWTGNALSPLDPETTRSSE-------LTLTPRPEDHGTNLTCQVKRQGAQVTTER 226
P +T+ +G + P D + + E LT+ D T + + + + +
Sbjct: 25347 PHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKA 25406
Query: 227 TVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSW 286
+ + + P + + F+ R+L+N QEGQS+ V PP +L W
Sbjct: 25407 KLTVTLHPPPTDSTLRPMFK-------RLLANA---ECQEGQSVCFEIRVSGIPPPTLKW 25456
Query: 287 FREGKALN 294
++G+ L+
Sbjct: 25457 EKDGQPLS 25464
Score = 30.8 bits (68), Expect = 2.2
Identities = 18/72 (25%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 264 IQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ----TSMSGTLELPNIGAREGGEFTC 319
I+ G +L L+ + P ++W +E + T + LE+ N +GG ++
Sbjct: 10858 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSL 10917
Query: 320 RVQHPLGSQHLS 331
V++P GS+ +S
Sbjct: 10918 TVENPAGSKTVS 10929
Score = 30.4 bits (67), Expect = 2.9
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 7/72 (9%)
Query: 264 IQEGQSLFL-ACTVDSNPPASLSWFREGKALNPSQ------TSMSGTLELPNIGAREGGE 316
I+ G ++ L A ++ P SW + GK + PS T S L + ++ GE
Sbjct: 14018 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 14077
Query: 317 FTCRVQHPLGSQ 328
+T +P G++
Sbjct: 14078 YTITATNPFGTK 14089
Score = 30.4 bits (67), Expect = 2.9
Identities = 17/77 (22%), Positives = 39/77 (50%), Gaps = 6/77 (7%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKAL-NPSQTSMSGTLELPNIGARE-----G 314
S +Q GQ L + + P +++W ++G L ++ +++ +L+L + +E G
Sbjct: 16866 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDG 16925
Query: 315 GEFTCRVQHPLGSQHLS 331
G++ V + +G + S
Sbjct: 16926 GQYGITVANVVGQKTAS 16942
Score = 29.6 bits (65), Expect = 5.0
Identities = 17/74 (22%), Positives = 34/74 (45%), Gaps = 8/74 (10%)
Query: 262 VPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ--------TSMSGTLELPNIGARE 313
+ I EG+ L +AC P ++W G+ ++ + T TL + ++ ++
Sbjct: 26966 ISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQD 27025
Query: 314 GGEFTCRVQHPLGS 327
GG +T + + GS
Sbjct: 27026 GGLYTLSLGNEFGS 27039
Score = 28.9 bits (63), Expect = 8.5
Identities = 17/72 (23%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ------TSMSGTLELPNIGAREG 314
+V ++ G++ L V PP ++ W ++GK L + S L + R+
Sbjct: 15098 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDS 15157
Query: 315 GEFTCRVQHPLG 326
G +T +P G
Sbjct: 15158 GAYTLTATNPGG 15169
Score = 28.9 bits (63), Expect = 8.5
Identities = 17/73 (23%), Positives = 32/73 (43%), Gaps = 6/73 (8%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGT------LELPNIGAREG 314
++ + G+ + L + PP + SWF G L S+ T L + R+
Sbjct: 23375 TIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDT 23434
Query: 315 GEFTCRVQHPLGS 327
GE+T +++ G+
Sbjct: 23435 GEYTLELKNVTGT 23447
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 57.4 bits (137), Expect = 2e-08
Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 11/115 (9%)
Query: 249 TGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPS------QTSMSG 302
T A RIL+ S+ + EG+S +C D P +++W R+G+ L+ S T
Sbjct: 26060 TTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKS 26119
Query: 303 TLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSSSCICVTEKQQGSWPLV 357
T E+ ++ A + G ++ V++ G Q F L++Q++ VTEK S P V
Sbjct: 26120 TFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR-----VTEKAVTSPPRV 26169
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 9/104 (8%)
Query: 255 ILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPS----QTSMSG--TLELPN 308
++S +V + EG+S+ L C + P +++W+RE + S T SG L +
Sbjct: 899 LVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIRE 958
Query: 309 IGAREGGEFTCRVQHPLGSQHLSFILSVQRS---SSSCICVTEK 349
A + G FTC + G+ S L+VQ S VTEK
Sbjct: 959 AFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEK 1002
Score = 36.6 bits (83), Expect = 0.041
Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 6/79 (7%)
Query: 264 IQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSG------TLELPNIGAREGGEF 317
++ G ++ L TV P ++SW ++G L P++ TLEL ++ ++ G++
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12869
Query: 318 TCRVQHPLGSQHLSFILSV 336
T ++ GS+ + L V
Sbjct: 12870 TITAENSSGSKSATIKLKV 12888
Score = 35.0 bits (79), Expect = 0.12
Identities = 27/108 (25%), Positives = 45/108 (41%), Gaps = 6/108 (5%)
Query: 236 PQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKAL-- 293
P+ A+SI + +G A I V + G++ L+C + P + W+R GK L
Sbjct: 24019 PRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ 24078
Query: 294 ----NPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ 337
S + TL + + G +TC + +G S L +Q
Sbjct: 24079 SRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24126
Score = 34.7 bits (78), Expect = 0.15
Identities = 18/74 (24%), Positives = 35/74 (47%), Gaps = 6/74 (8%)
Query: 256 LSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALN-PSQTSMSG-----TLELPNI 309
+S S I EGQ++ C + P + WF+ ++ S S+S +LE+ N
Sbjct: 26640 ISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNA 26699
Query: 310 GAREGGEFTCRVQH 323
+ G++T + ++
Sbjct: 26700 SVSDSGKYTIKAKN 26713
Score = 34.3 bits (77), Expect = 0.20
Identities = 59/267 (22%), Positives = 99/267 (37%), Gaps = 47/267 (17%)
Query: 96 VQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEP-- 153
V+++ + I + R D G Y F R R + + L V A + L+P
Sbjct: 3152 VERRIHRMFISETRQSDAGEYTFVAGRNR--------SSVTLYVNAPEPPQVLQELQPVT 3203
Query: 154 LESGRPTRLSCSLPGSCEAGPPLTFSW--------TGNALSPLDPETTRSSELTLTPRPE 205
++SG+P R + G P SW TG L + + L + PE
Sbjct: 3204 VQSGKPARFCAVISGR----PQPKISWYKEEQLLSTGFKCKFLH-DGQEYTLLLIEAFPE 3258
Query: 206 DHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQ 265
D TC+ K TT ++ + V P+ ++ + + + P+Q
Sbjct: 3259 DAAV-YTCEAKNDYGVATTSASLSVEV---PEVVS--------PDQEMPVYPPAIITPLQ 3306
Query: 266 -----EGQSLFLACTVDSNPPASLSWFREGKALNPSQ----TSMSGT--LELPNIGAREG 314
EGQ C V S +SW+ + K + PS+ T T LE+ +
Sbjct: 3307 DTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDE 3365
Query: 315 GEFTCRVQHPLGSQHLSFILSVQRSSS 341
G +T + +G + LS++ S
Sbjct: 3366 GTYTFVASNAVGQVSSTANLSLEAPES 3392
Score = 34.3 bits (77), Expect = 0.20
Identities = 21/94 (22%), Positives = 41/94 (43%), Gaps = 4/94 (4%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKALNP----SQTSMSGTLELPNIGAREGGE 316
+V I+ G SL L +V PP ++W ++G L T L + + + G+
Sbjct: 22958 TVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGK 23017
Query: 317 FTCRVQHPLGSQHLSFILSVQRSSSSCICVTEKQ 350
+T ++ G + + ++ V + C V K+
Sbjct: 23018 YTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKE 23051
Score = 32.0 bits (71), Expect = 1.0
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 6/77 (7%)
Query: 266 EGQSLFLACTVDSNPPASLSWFREGKALNPS------QTSMSGTLELPNIGAREGGEFTC 319
EG+ L + + P ++SW ++GK + S +S LE+P + G +T
Sbjct: 7903 EGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTI 7962
Query: 320 RVQHPLGSQHLSFILSV 336
+++ LGS S + V
Sbjct: 7963 TLENKLGSATASINVKV 7979
Score = 31.6 bits (70), Expect = 1.3
Identities = 31/147 (21%), Positives = 54/147 (36%), Gaps = 17/147 (11%)
Query: 208 GTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFF---RNGTGTAL--------RIL 256
G + QV+ + V R ++ +S Q+ A F RN + L ++L
Sbjct: 3137 GIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVL 3196
Query: 257 SNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPS------QTSMSGTLELPNIG 310
V +Q G+ + P +SW++E + L+ TL L
Sbjct: 3197 QELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAF 3256
Query: 311 AREGGEFTCRVQHPLGSQHLSFILSVQ 337
+ +TC ++ G S LSV+
Sbjct: 3257 PEDAAVYTCEAKNDYGVATTSASLSVE 3283
Score = 31.6 bits (70), Expect = 1.3
Identities = 17/69 (24%), Positives = 30/69 (43%), Gaps = 6/69 (8%)
Query: 274 CTVDSNPPASLSWFREGKALNPS------QTSMSGTLELPNIGAREGGEFTCRVQHPLGS 327
C + S P WF+ G+ + S + +LE+ + GE+TC+ + GS
Sbjct: 4358 CEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGS 4417
Query: 328 QHLSFILSV 336
+ L+V
Sbjct: 4418 VSCTATLTV 4426
Score = 31.2 bits (69), Expect = 1.7
Identities = 27/128 (21%), Positives = 53/128 (41%), Gaps = 17/128 (13%)
Query: 174 PPLTFSWTGNALSPLDPETTRSSE-------LTLTPRPEDHGTNLTCQVKRQGAQVTTER 226
P +T+ +G + P D + + E LT+ D T + + + + +
Sbjct: 25222 PHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKA 25281
Query: 227 TVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSW 286
+ + + P + + F+ R+L+N QEGQS+ V PP +L W
Sbjct: 25282 KLTVTLHPPPTDSTLRPMFK-------RLLANA---ECQEGQSVCFEIRVSGIPPPTLKW 25331
Query: 287 FREGKALN 294
++G+ L+
Sbjct: 25332 EKDGQPLS 25339
Score = 30.8 bits (68), Expect = 2.2
Identities = 18/72 (25%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 264 IQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ----TSMSGTLELPNIGAREGGEFTC 319
I+ G +L L+ + P ++W +E + T + LE+ N +GG ++
Sbjct: 10733 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSL 10792
Query: 320 RVQHPLGSQHLS 331
V++P GS+ +S
Sbjct: 10793 TVENPAGSKTVS 10804
Score = 30.4 bits (67), Expect = 2.9
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 7/72 (9%)
Query: 264 IQEGQSLFL-ACTVDSNPPASLSWFREGKALNPSQ------TSMSGTLELPNIGAREGGE 316
I+ G ++ L A ++ P SW + GK + PS T S L + ++ GE
Sbjct: 13893 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 13952
Query: 317 FTCRVQHPLGSQ 328
+T +P G++
Sbjct: 13953 YTITATNPFGTK 13964
Score = 30.4 bits (67), Expect = 2.9
Identities = 17/77 (22%), Positives = 39/77 (50%), Gaps = 6/77 (7%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKAL-NPSQTSMSGTLELPNIGARE-----G 314
S +Q GQ L + + P +++W ++G L ++ +++ +L+L + +E G
Sbjct: 16741 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDG 16800
Query: 315 GEFTCRVQHPLGSQHLS 331
G++ V + +G + S
Sbjct: 16801 GQYGITVANVVGQKTAS 16817
Score = 29.6 bits (65), Expect = 5.0
Identities = 17/74 (22%), Positives = 34/74 (45%), Gaps = 8/74 (10%)
Query: 262 VPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ--------TSMSGTLELPNIGARE 313
+ I EG+ L +AC P ++W G+ ++ + T TL + ++ ++
Sbjct: 26841 ISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQD 26900
Query: 314 GGEFTCRVQHPLGS 327
GG +T + + GS
Sbjct: 26901 GGLYTLSLGNEFGS 26914
Score = 28.9 bits (63), Expect = 8.5
Identities = 17/72 (23%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQ------TSMSGTLELPNIGAREG 314
+V ++ G++ L V PP ++ W ++GK L + S L + R+
Sbjct: 14973 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDS 15032
Query: 315 GEFTCRVQHPLG 326
G +T +P G
Sbjct: 15033 GAYTLTATNPGG 15044
Score = 28.9 bits (63), Expect = 8.5
Identities = 17/73 (23%), Positives = 32/73 (43%), Gaps = 6/73 (8%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGT------LELPNIGAREG 314
++ + G+ + L + PP + SWF G L S+ T L + R+
Sbjct: 23250 TIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDT 23309
Query: 315 GEFTCRVQHPLGS 327
GE+T +++ G+
Sbjct: 23310 GEYTLELKNVTGT 23322
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 55.5 bits (132), Expect = 8e-08
Identities = 53/192 (27%), Positives = 79/192 (41%), Gaps = 34/192 (17%)
Query: 165 SLPGSCEAGPPLTFSWTG--NALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQ--GA 220
SLP P T +WT NAL+ P S E GT L Q Q GA
Sbjct: 877 SLPCVASGVPAPTITWTKETNALTSRGPHYNVSKE----------GTLLIAQPSAQDAGA 926
Query: 221 QVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGM---SVPIQ----EGQSLFLA 273
V T V ++ Q + +S+ T RI NG +VP+Q G+ + L
Sbjct: 927 YVCTATNT---VGFSSQEMRLSV------NTKPRIHMNGSRNANVPLQVTAKAGEEVTLD 977
Query: 274 CTVDSNPPASLSWFREGKALNPSQTSM----SGTLELPNIGAREGGEFTCRVQHPLGSQH 329
C +PP ++W ++ + + P SG+L L + + G + C +P GS
Sbjct: 978 CEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSAS 1037
Query: 330 LSFILSVQRSSS 341
++L VQ +S
Sbjct: 1038 HRYVLGVQGRTS 1049
Score = 45.4 bits (106), Expect = 9e-05
Identities = 75/345 (21%), Positives = 122/345 (35%), Gaps = 76/345 (22%)
Query: 33 EGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRL 92
+G+ V V CS S Y +P ++ W R+ + D R+ + QG
Sbjct: 504 QGVEVKVSCS-----ASGYPTP--HISWSRESQ---------ALQEDSRIHVDAQG---- 543
Query: 93 LGDVQKKNCSLSIGDARMEDTGSYFFRV--ERGRDVKYSYQQNKLNLEVTALIEKPDIHF 150
+L I ED G+Y + E G D Q + L T ++
Sbjct: 544 ---------TLIIQGVAPEDAGNYSCQATNEVGTD------QETVTLYYTDPPSVSAVNA 588
Query: 151 LEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTN 210
+ + G L C G PP + G L PE + S +L + E
Sbjct: 589 VVLVAVGEEAVLVCEASG---VPPPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGT 645
Query: 211 LTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSL 270
TC+ + + E +QL V +APQ + V ++ G+S
Sbjct: 646 YTCRAVNELGDASAE--IQLAVGHAPQLTELP-----------------RDVTVELGRSA 686
Query: 271 FLACTVDSNPPASLSWFR-EGKAL---------NPSQTSMSGTLELPNIGAREGGEFTCR 320
LAC PP +++W R +G+ L + S+ SG L ++ + + C
Sbjct: 687 LLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCE 746
Query: 321 VQHPLGSQHLSFILSVQ-------RSSSSCICVTEKQQGSWPLVL 358
++ G L V SS+ + V E Q S P ++
Sbjct: 747 ARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIV 791
Score = 40.0 bits (92), Expect = 0.004
Identities = 48/199 (24%), Positives = 72/199 (36%), Gaps = 37/199 (18%)
Query: 154 LESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPET-----TRSSE------LTLTP 202
+E GR L+C G PP T +W PL +RS + +
Sbjct: 680 VELGRSALLACRATGR----PPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESV 735
Query: 203 RPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSV 262
PED + C+ + +V E + + PQ I S+ +V
Sbjct: 736 APEDQAPYV-CEARNVFGKVQAEARLIVTGHAPPQ-----------------IASSAPTV 777
Query: 263 PIQEGQSLFLACTVDSNPPA-SLSWFREGKALNPSQTSM---SGTLELPNIGAREGGEFT 318
+ EGQ + L C V + P W ++G+ L P G+L L G ++
Sbjct: 778 RVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYS 837
Query: 319 CRVQHPLGSQHLSFILSVQ 337
C + GSQH L VQ
Sbjct: 838 CVATNTAGSQHRDVELVVQ 856
Score = 34.3 bits (77), Expect = 0.20
Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Query: 261 SVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSG-----TLELPNIGAREGG 315
+V + G++ L+C V P +L+W R+ + L P+ T +LE+ I +GG
Sbjct: 408 NVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVL-PASTGRVAQLADLSLEISGIIPTDGG 466
Query: 316 EFTCRVQHPLGSQHLSFILSVQRS 339
+ C + G S L V+ +
Sbjct: 467 RYQCVASNANGVTRASVWLLVREA 490
Score = 33.5 bits (75), Expect = 0.34
Identities = 47/199 (23%), Positives = 69/199 (34%), Gaps = 35/199 (17%)
Query: 146 PDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRS----SELTLT 201
P + LE G+P L C + AG PL PL P + S L L
Sbjct: 775 PTVRVLE----GQPVSLPCIVL----AGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLD 826
Query: 202 PRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMS 261
++H +C + R V+L V P+ TA ++N
Sbjct: 827 RALQEHAGRYSCVATNTAG--SQHRDVELVVQVPPRIHP----------TATHHITN--- 871
Query: 262 VPIQEGQSLFLACTVDSNPPASLSWFREGKALNPS----QTSMSGTLELPNIGAREGGEF 317
EG L C P +++W +E AL S GTL + A++ G +
Sbjct: 872 ----EGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAY 927
Query: 318 TCRVQHPLGSQHLSFILSV 336
C + +G LSV
Sbjct: 928 VCTATNTVGFSSQEMRLSV 946
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,246,129
Number of Sequences: 37866
Number of extensions: 841113
Number of successful extensions: 3768
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 125
Number of HSP's successfully gapped in prelim test: 237
Number of HSP's that attempted gapping in prelim test: 2320
Number of HSP's gapped (non-prelim): 1298
length of query: 396
length of database: 18,247,518
effective HSP length: 104
effective length of query: 292
effective length of database: 14,309,454
effective search space: 4178360568
effective search space used: 4178360568
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.