Guide to the Human Genome
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Search of human proteins with 148747864

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148747864 JAW1-related protein isoform a [Homo sapiens]
         (903 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148747864 JAW1-related protein isoform a [Homo sapiens]           1803   0.0  
gi|154091332 JAW1-related protein isoform b [Homo sapiens]           1630   0.0  
gi|148728182 JAW1-related protein isoform b [Homo sapiens]           1630   0.0  
gi|154091334 JAW1-related protein isoform c [Homo sapiens]           1183   0.0  
gi|42789729 lymphoid-restricted membrane protein [Homo sapiens]       133   7e-31
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    61   4e-09
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     60   1e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni...    56   1e-07
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    55   4e-07
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   54   5e-07
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   54   5e-07
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   54   5e-07
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    54   5e-07
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       54   5e-07
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    54   5e-07
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     54   9e-07
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     54   9e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    53   1e-06
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    52   2e-06
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    52   2e-06
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    52   2e-06
gi|44662807 hypothetical protein LOC388407 [Homo sapiens]              52   3e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    51   4e-06
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...    51   4e-06
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    51   6e-06
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    51   6e-06
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    51   6e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    50   7e-06
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  50   9e-06
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      50   1e-05

>gi|148747864 JAW1-related protein isoform a [Homo sapiens]
          Length = 903

 Score = 1803 bits (4670), Expect = 0.0
 Identities = 903/903 (100%), Positives = 903/903 (100%)

Query: 1   MGMDLTCPFGVSPACGAQASWSIFGADAAEVPGTRGHSQQEAAMPHIPEDEEPPGEPQAA 60
           MGMDLTCPFGVSPACGAQASWSIFGADAAEVPGTRGHSQQEAAMPHIPEDEEPPGEPQAA
Sbjct: 1   MGMDLTCPFGVSPACGAQASWSIFGADAAEVPGTRGHSQQEAAMPHIPEDEEPPGEPQAA 60

Query: 61  QSPAGQGPPTAGVSCSPTPTIVLTGDATSPEGETDKNLANRVHSPHKRLSHRHLKVSTAS 120
           QSPAGQGPPTAGVSCSPTPTIVLTGDATSPEGETDKNLANRVHSPHKRLSHRHLKVSTAS
Sbjct: 61  QSPAGQGPPTAGVSCSPTPTIVLTGDATSPEGETDKNLANRVHSPHKRLSHRHLKVSTAS 120

Query: 121 LTSVDPAGHIIDLVNDQLPDISISEEDKKKNLALLEEAKLVSERFLTRRGRKSRSSPGDS 180
           LTSVDPAGHIIDLVNDQLPDISISEEDKKKNLALLEEAKLVSERFLTRRGRKSRSSPGDS
Sbjct: 121 LTSVDPAGHIIDLVNDQLPDISISEEDKKKNLALLEEAKLVSERFLTRRGRKSRSSPGDS 180

Query: 181 PSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGE 240
           PSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGE
Sbjct: 181 PSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGE 240

Query: 241 PNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPV 300
           PNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPV
Sbjct: 241 PNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPV 300

Query: 301 TNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEP 360
           TNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEP
Sbjct: 301 TNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEP 360

Query: 361 MGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGK 420
           MGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGK
Sbjct: 361 MGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGK 420

Query: 421 LAKAPGLKDFQIQVQPVRMQKLTKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELS 480
           LAKAPGLKDFQIQVQPVRMQKLTKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELS
Sbjct: 421 LAKAPGLKDFQIQVQPVRMQKLTKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELS 480

Query: 481 PAIEEEESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSY 540
           PAIEEEESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSY
Sbjct: 481 PAIEEEESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSY 540

Query: 541 TLESRINQAERERNLTEENTEKELENFKASITSSASLWHHCEHRETYQKLLEDIAVLHRL 600
           TLESRINQAERERNLTEENTEKELENFKASITSSASLWHHCEHRETYQKLLEDIAVLHRL
Sbjct: 541 TLESRINQAERERNLTEENTEKELENFKASITSSASLWHHCEHRETYQKLLEDIAVLHRL 600

Query: 601 AARLSSRAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSC 660
           AARLSSRAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSC
Sbjct: 601 AARLSSRAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSC 660

Query: 661 GPSEDGVPRTARSMSLTLGKNMPRRRVSVAVVPKFNALNLPGQTPSSSSIPSLPALSESP 720
           GPSEDGVPRTARSMSLTLGKNMPRRRVSVAVVPKFNALNLPGQTPSSSSIPSLPALSESP
Sbjct: 661 GPSEDGVPRTARSMSLTLGKNMPRRRVSVAVVPKFNALNLPGQTPSSSSIPSLPALSESP 720

Query: 721 NGKGSLPVTSALPALLENGKTNGDPDCEASAPALTLSCLEELSQETKARMEEEAYSKGFQ 780
           NGKGSLPVTSALPALLENGKTNGDPDCEASAPALTLSCLEELSQETKARMEEEAYSKGFQ
Sbjct: 721 NGKGSLPVTSALPALLENGKTNGDPDCEASAPALTLSCLEELSQETKARMEEEAYSKGFQ 780

Query: 781 EGLKKTKELQDLKEEEEEQKSESPEEPEEVEETEEEEKGPRSSKLEELVHFLQVMYPKLC 840
           EGLKKTKELQDLKEEEEEQKSESPEEPEEVEETEEEEKGPRSSKLEELVHFLQVMYPKLC
Sbjct: 781 EGLKKTKELQDLKEEEEEQKSESPEEPEEVEETEEEEKGPRSSKLEELVHFLQVMYPKLC 840

Query: 841 QHWQVIWMMAAVMLVLTVVLGLYNSYNSCAEQADGPLGRSTCSAAQRDSWWSSGLQHEQP 900
           QHWQVIWMMAAVMLVLTVVLGLYNSYNSCAEQADGPLGRSTCSAAQRDSWWSSGLQHEQP
Sbjct: 841 QHWQVIWMMAAVMLVLTVVLGLYNSYNSCAEQADGPLGRSTCSAAQRDSWWSSGLQHEQP 900

Query: 901 TEQ 903
           TEQ
Sbjct: 901 TEQ 903


>gi|154091332 JAW1-related protein isoform b [Homo sapiens]
          Length = 821

 Score = 1630 bits (4220), Expect = 0.0
 Identities = 820/821 (99%), Positives = 821/821 (100%)

Query: 83  LTGDATSPEGETDKNLANRVHSPHKRLSHRHLKVSTASLTSVDPAGHIIDLVNDQLPDIS 142
           +TGDATSPEGETDKNLANRVHSPHKRLSHRHLKVSTASLTSVDPAGHIIDLVNDQLPDIS
Sbjct: 1   MTGDATSPEGETDKNLANRVHSPHKRLSHRHLKVSTASLTSVDPAGHIIDLVNDQLPDIS 60

Query: 143 ISEEDKKKNLALLEEAKLVSERFLTRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSL 202
           ISEEDKKKNLALLEEAKLVSERFLTRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSL
Sbjct: 61  ISEEDKKKNLALLEEAKLVSERFLTRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSL 120

Query: 203 TVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGR 262
           TVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGR
Sbjct: 121 TVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGR 180

Query: 263 LAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELG 322
           LAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELG
Sbjct: 181 LAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELG 240

Query: 323 KQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLR 382
           KQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLR
Sbjct: 241 KQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLR 300

Query: 383 GLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKAPGLKDFQIQVQPVRMQKL 442
           GLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKAPGLKDFQIQVQPVRMQKL
Sbjct: 301 GLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKAPGLKDFQIQVQPVRMQKL 360

Query: 443 TKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELSPAIEEEESKSGLDVMPNISDVL 502
           TKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELSPAIEEEESKSGLDVMPNISDVL
Sbjct: 361 TKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELSPAIEEEESKSGLDVMPNISDVL 420

Query: 503 LRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSYTLESRINQAERERNLTEENTEK 562
           LRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSYTLESRINQAERERNLTEENTEK
Sbjct: 421 LRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSYTLESRINQAERERNLTEENTEK 480

Query: 563 ELENFKASITSSASLWHHCEHRETYQKLLEDIAVLHRLAARLSSRAEVVGAVRQEKRMSK 622
           ELENFKASITSSASLWHHCEHRETYQKLLEDIAVLHRLAARLSSRAEVVGAVRQEKRMSK
Sbjct: 481 ELENFKASITSSASLWHHCEHRETYQKLLEDIAVLHRLAARLSSRAEVVGAVRQEKRMSK 540

Query: 623 ATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSCGPSEDGVPRTARSMSLTLGKNM 682
           ATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSCGPSEDGVPRTARSMSLTLGKNM
Sbjct: 541 ATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSCGPSEDGVPRTARSMSLTLGKNM 600

Query: 683 PRRRVSVAVVPKFNALNLPGQTPSSSSIPSLPALSESPNGKGSLPVTSALPALLENGKTN 742
           PRRRVSVAVVPKFNALNLPGQTPSSSSIPSLPALSESPNGKGSLPVTSALPALLENGKTN
Sbjct: 601 PRRRVSVAVVPKFNALNLPGQTPSSSSIPSLPALSESPNGKGSLPVTSALPALLENGKTN 660

Query: 743 GDPDCEASAPALTLSCLEELSQETKARMEEEAYSKGFQEGLKKTKELQDLKEEEEEQKSE 802
           GDPDCEASAPALTLSCLEELSQETKARMEEEAYSKGFQEGLKKTKELQDLKEEEEEQKSE
Sbjct: 661 GDPDCEASAPALTLSCLEELSQETKARMEEEAYSKGFQEGLKKTKELQDLKEEEEEQKSE 720

Query: 803 SPEEPEEVEETEEEEKGPRSSKLEELVHFLQVMYPKLCQHWQVIWMMAAVMLVLTVVLGL 862
           SPEEPEEVEETEEEEKGPRSSKLEELVHFLQVMYPKLCQHWQVIWMMAAVMLVLTVVLGL
Sbjct: 721 SPEEPEEVEETEEEEKGPRSSKLEELVHFLQVMYPKLCQHWQVIWMMAAVMLVLTVVLGL 780

Query: 863 YNSYNSCAEQADGPLGRSTCSAAQRDSWWSSGLQHEQPTEQ 903
           YNSYNSCAEQADGPLGRSTCSAAQRDSWWSSGLQHEQPTEQ
Sbjct: 781 YNSYNSCAEQADGPLGRSTCSAAQRDSWWSSGLQHEQPTEQ 821


>gi|148728182 JAW1-related protein isoform b [Homo sapiens]
          Length = 821

 Score = 1630 bits (4220), Expect = 0.0
 Identities = 820/821 (99%), Positives = 821/821 (100%)

Query: 83  LTGDATSPEGETDKNLANRVHSPHKRLSHRHLKVSTASLTSVDPAGHIIDLVNDQLPDIS 142
           +TGDATSPEGETDKNLANRVHSPHKRLSHRHLKVSTASLTSVDPAGHIIDLVNDQLPDIS
Sbjct: 1   MTGDATSPEGETDKNLANRVHSPHKRLSHRHLKVSTASLTSVDPAGHIIDLVNDQLPDIS 60

Query: 143 ISEEDKKKNLALLEEAKLVSERFLTRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSL 202
           ISEEDKKKNLALLEEAKLVSERFLTRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSL
Sbjct: 61  ISEEDKKKNLALLEEAKLVSERFLTRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSL 120

Query: 203 TVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGR 262
           TVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGR
Sbjct: 121 TVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGR 180

Query: 263 LAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELG 322
           LAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELG
Sbjct: 181 LAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELG 240

Query: 323 KQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLR 382
           KQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLR
Sbjct: 241 KQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLR 300

Query: 383 GLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKAPGLKDFQIQVQPVRMQKL 442
           GLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKAPGLKDFQIQVQPVRMQKL
Sbjct: 301 GLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKAPGLKDFQIQVQPVRMQKL 360

Query: 443 TKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELSPAIEEEESKSGLDVMPNISDVL 502
           TKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELSPAIEEEESKSGLDVMPNISDVL
Sbjct: 361 TKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELSPAIEEEESKSGLDVMPNISDVL 420

Query: 503 LRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSYTLESRINQAERERNLTEENTEK 562
           LRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSYTLESRINQAERERNLTEENTEK
Sbjct: 421 LRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSYTLESRINQAERERNLTEENTEK 480

Query: 563 ELENFKASITSSASLWHHCEHRETYQKLLEDIAVLHRLAARLSSRAEVVGAVRQEKRMSK 622
           ELENFKASITSSASLWHHCEHRETYQKLLEDIAVLHRLAARLSSRAEVVGAVRQEKRMSK
Sbjct: 481 ELENFKASITSSASLWHHCEHRETYQKLLEDIAVLHRLAARLSSRAEVVGAVRQEKRMSK 540

Query: 623 ATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSCGPSEDGVPRTARSMSLTLGKNM 682
           ATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSCGPSEDGVPRTARSMSLTLGKNM
Sbjct: 541 ATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSCGPSEDGVPRTARSMSLTLGKNM 600

Query: 683 PRRRVSVAVVPKFNALNLPGQTPSSSSIPSLPALSESPNGKGSLPVTSALPALLENGKTN 742
           PRRRVSVAVVPKFNALNLPGQTPSSSSIPSLPALSESPNGKGSLPVTSALPALLENGKTN
Sbjct: 601 PRRRVSVAVVPKFNALNLPGQTPSSSSIPSLPALSESPNGKGSLPVTSALPALLENGKTN 660

Query: 743 GDPDCEASAPALTLSCLEELSQETKARMEEEAYSKGFQEGLKKTKELQDLKEEEEEQKSE 802
           GDPDCEASAPALTLSCLEELSQETKARMEEEAYSKGFQEGLKKTKELQDLKEEEEEQKSE
Sbjct: 661 GDPDCEASAPALTLSCLEELSQETKARMEEEAYSKGFQEGLKKTKELQDLKEEEEEQKSE 720

Query: 803 SPEEPEEVEETEEEEKGPRSSKLEELVHFLQVMYPKLCQHWQVIWMMAAVMLVLTVVLGL 862
           SPEEPEEVEETEEEEKGPRSSKLEELVHFLQVMYPKLCQHWQVIWMMAAVMLVLTVVLGL
Sbjct: 721 SPEEPEEVEETEEEEKGPRSSKLEELVHFLQVMYPKLCQHWQVIWMMAAVMLVLTVVLGL 780

Query: 863 YNSYNSCAEQADGPLGRSTCSAAQRDSWWSSGLQHEQPTEQ 903
           YNSYNSCAEQADGPLGRSTCSAAQRDSWWSSGLQHEQPTEQ
Sbjct: 781 YNSYNSCAEQADGPLGRSTCSAAQRDSWWSSGLQHEQPTEQ 821


>gi|154091334 JAW1-related protein isoform c [Homo sapiens]
          Length = 597

 Score = 1183 bits (3061), Expect = 0.0
 Identities = 597/597 (100%), Positives = 597/597 (100%)

Query: 307 MALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAG 366
           MALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAG
Sbjct: 1   MALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAG 60

Query: 367 SKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKAPG 426
           SKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKAPG
Sbjct: 61  SKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKAPG 120

Query: 427 LKDFQIQVQPVRMQKLTKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELSPAIEEE 486
           LKDFQIQVQPVRMQKLTKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELSPAIEEE
Sbjct: 121 LKDFQIQVQPVRMQKLTKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELSPAIEEE 180

Query: 487 ESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSYTLESRI 546
           ESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSYTLESRI
Sbjct: 181 ESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSYTLESRI 240

Query: 547 NQAERERNLTEENTEKELENFKASITSSASLWHHCEHRETYQKLLEDIAVLHRLAARLSS 606
           NQAERERNLTEENTEKELENFKASITSSASLWHHCEHRETYQKLLEDIAVLHRLAARLSS
Sbjct: 241 NQAERERNLTEENTEKELENFKASITSSASLWHHCEHRETYQKLLEDIAVLHRLAARLSS 300

Query: 607 RAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSCGPSEDG 666
           RAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSCGPSEDG
Sbjct: 301 RAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSCGPSEDG 360

Query: 667 VPRTARSMSLTLGKNMPRRRVSVAVVPKFNALNLPGQTPSSSSIPSLPALSESPNGKGSL 726
           VPRTARSMSLTLGKNMPRRRVSVAVVPKFNALNLPGQTPSSSSIPSLPALSESPNGKGSL
Sbjct: 361 VPRTARSMSLTLGKNMPRRRVSVAVVPKFNALNLPGQTPSSSSIPSLPALSESPNGKGSL 420

Query: 727 PVTSALPALLENGKTNGDPDCEASAPALTLSCLEELSQETKARMEEEAYSKGFQEGLKKT 786
           PVTSALPALLENGKTNGDPDCEASAPALTLSCLEELSQETKARMEEEAYSKGFQEGLKKT
Sbjct: 421 PVTSALPALLENGKTNGDPDCEASAPALTLSCLEELSQETKARMEEEAYSKGFQEGLKKT 480

Query: 787 KELQDLKEEEEEQKSESPEEPEEVEETEEEEKGPRSSKLEELVHFLQVMYPKLCQHWQVI 846
           KELQDLKEEEEEQKSESPEEPEEVEETEEEEKGPRSSKLEELVHFLQVMYPKLCQHWQVI
Sbjct: 481 KELQDLKEEEEEQKSESPEEPEEVEETEEEEKGPRSSKLEELVHFLQVMYPKLCQHWQVI 540

Query: 847 WMMAAVMLVLTVVLGLYNSYNSCAEQADGPLGRSTCSAAQRDSWWSSGLQHEQPTEQ 903
           WMMAAVMLVLTVVLGLYNSYNSCAEQADGPLGRSTCSAAQRDSWWSSGLQHEQPTEQ
Sbjct: 541 WMMAAVMLVLTVVLGLYNSYNSCAEQADGPLGRSTCSAAQRDSWWSSGLQHEQPTEQ 597


>gi|42789729 lymphoid-restricted membrane protein [Homo sapiens]
          Length = 499

 Score =  133 bits (335), Expect = 7e-31
 Identities = 89/215 (41%), Positives = 128/215 (59%), Gaps = 12/215 (5%)

Query: 485 EEESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSYTLES 544
           ++E  SG  V+  +    ++ + + +S   SA    EKEVE  F++LSL F+ D +TLE 
Sbjct: 118 KKEHASGDSVVSPLPVTTVKSVNLRQSENTSA---NEKEVEAEFLRLSLGFKCDWFTLEK 174

Query: 545 RINQAERERNLTEENTEKELENFKASITSSASLWHHCEH----RETYQKLLEDIAVLHRL 600
           R+   ER R+L EEN +KE+ N    + S   L   CE     +E  +KL + I  L + 
Sbjct: 175 RVKLEERSRDLAEENLKKEITNCLKLLESLTPL---CEDDNQAQEIIKKLEKSIKFLSQC 231

Query: 601 AARLSSRAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSC 660
           AAR++SRAE++GA+ QE R+SKA EVM+Q+VENLKR Y K+HAEL E K++  QN  RS 
Sbjct: 232 AARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAELEELKQVLLQN-ERSF 290

Query: 661 GPSEDGVPRTARSMSLTL-GKNMPRRRVSVAVVPK 694
            P ED      +  S +L  K    RRV++A +P+
Sbjct: 291 NPLEDDDDCQIKKRSASLNSKPSSLRRVTIASLPR 325


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 54/191 (28%), Positives = 73/191 (38%), Gaps = 29/191 (15%)

Query: 205 PTPPGLDVCSGPPSPL---PGAPPQKGDEADVSSPHPGEPNVP--------KGLADRKQN 253
           P P G +   GPP P     G PPQ G+++    PHPG+P  P        +G       
Sbjct: 60  PPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGK 119

Query: 254 DQRKVSQG---RLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALN 310
            +R   QG      P PPP +  +       ++  P  +P   P+G  P   +  + A +
Sbjct: 120 PERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHP-GKPEGPPPQEGNKSRSARS 178

Query: 311 SP--QPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSK 368
            P    GP + E  K       +G P P  P       G P      PAG+P GP     
Sbjct: 179 PPGKPQGPPQQEGNKP------QGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPP--- 229

Query: 369 AELPPTVSRPP 379
              PP   RPP
Sbjct: 230 ---PPQGGRPP 237



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 45/171 (26%), Positives = 59/171 (34%), Gaps = 28/171 (16%)

Query: 216 PPSPLPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKE 275
           PP    G PPQ G+++    P PG+P            + R    G  +  PPP     E
Sbjct: 53  PPGKPQGPPPQGGNQSQGPPPPPGKP------------EGRPPQGGNQSQGPPPHPGKPE 100

Query: 276 IAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPL 335
               Q  N      P   P G        G    + P P P     GK        G+  
Sbjct: 101 RPPPQGGNQSQGTPP---PPGKPERPPPQGGNQSHRPPPPP-----GKPERPPPQGGNQS 152

Query: 336 PRSPTQDAAGVGPPASQG------RGPAGEPMGP--EAGSKAELPPTVSRP 378
              P       GPP  +G      R P G+P GP  + G+K + PP   +P
Sbjct: 153 QGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKP 203


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 65/234 (27%), Positives = 84/234 (35%), Gaps = 23/234 (9%)

Query: 177 PGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSP--LPGAPPQKGDEADVS 234
           P   P    P    S SP S        P P G +   GPP P   P  PP +G      
Sbjct: 94  PPGKPQGPPPQGDKSRSPRSPPGKPQG-PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 152

Query: 235 SPHPGEPNVPKGLADRKQNDQRKVS--------QGRLAPR-PPPVEKSKEIAIEQKENFD 285
            P PG+P  P    D K    R           QG   P+ PPP     +    Q  N  
Sbjct: 153 PPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 212

Query: 286 PLQYPETTPKGLAPVTNSSGKMALNSP-QPGPVESELGKQLLKTGWEGSPLPRSPTQDAA 344
               P   P+G  P  ++  + A + P +P     + G Q      +G P P    Q   
Sbjct: 213 QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQP-----QGPPPPPGKPQGPP 267

Query: 345 GVGPPASQGRGPAGEPMG--PEAGSK---AELPPTVSRPPLLRGLSWDSGPEEP 393
             G    QG  P G+P G  P+ GSK   +  PP   + P  +G +   GP  P
Sbjct: 268 PQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPP 321



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 71/275 (25%), Positives = 97/275 (35%), Gaps = 33/275 (12%)

Query: 178 GDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGL---------DVCSGPPSP--LPGAPPQ 226
           G+ P    P   P   P    + S +  +PPG          +   GPP P   P  PP 
Sbjct: 147 GNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206

Query: 227 KGDEADVSSPHPGEPNVPKGLADRKQNDQRKVS--------QGRLAPR-PPPVEKSKEIA 277
           +G       P PG+P  P    D K    R           QG   P+ PPP     +  
Sbjct: 207 QGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 266

Query: 278 IEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSP-QPGPVESELGKQLLKTGWEGSPLP 336
             Q  N      P   P+G  P   S  + + + P +P     + G Q      +G P P
Sbjct: 267 PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQP-----QGPPPP 321

Query: 337 RSPTQDAAGVGPPASQGRGPAGEPMG--PEAGSK---AELPPTVSR-PPLLRGLSWDSGP 390
               Q     G    QG  P G+P G  P+ GSK   A  PP   + PP   G +    P
Sbjct: 322 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPP 381

Query: 391 EEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKAP 425
              G   Q+  A  P  + +       GG+ ++ P
Sbjct: 382 PPAGGNPQQPQAP-PAGQPQGPPRPPQGGRPSRPP 415



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 59/229 (25%), Positives = 86/229 (37%), Gaps = 38/229 (16%)

Query: 180 SPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPL---PGAPPQKGDEADVSSP 236
           S   ++ ++S   SP+    N    P P G +   GPPSP     G PPQ G++     P
Sbjct: 15  SAQNLNEDVSQEESPSLIAGNPQGAP-PQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPP 73

Query: 237 HPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKG 296
            PG+P  P               QG   P+ PP     +    Q +     + P   P+G
Sbjct: 74  PPGKPQGPP-------------PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 120

Query: 297 LAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPP------A 350
             P     G      P P P + +          +G   P+ P       GPP      +
Sbjct: 121 PPP----QGGNQPQGPPPPPGKPQGPPP------QGGNKPQGPPPPGKPQGPPPQGDNKS 170

Query: 351 SQGRGPAGEPMG--PEAGSKAE-LPPTVSRP--PLLRGLSWDSGPEEPG 394
              R P G+P G  P+ G++ +  PP   +P  P  +G +   GP  PG
Sbjct: 171 RSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 219


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 93/415 (22%), Positives = 127/415 (30%), Gaps = 37/415 (8%)

Query: 48   PEDEEPPGEPQAAQSPAGQGPPTAGVSCSPTPTIVLTGDATSPE---GETDKNLANRVHS 104
            P    PP    +  +P  +G PT      P+P    T  AT+P    G T  +       
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP 1371

Query: 105  PHKRLSHRHLKVSTASLTSVDPAGHIIDLVNDQLPDISISEEDKKKNLALLEEAKLVSER 164
            P    SH+     T       PA             I   + D      +    K     
Sbjct: 1372 PAATPSHKGGPAMTPPSPKRGPA-------------IPSPKGDPTSPAVIPLSPKKAPAT 1418

Query: 165  FLTRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAP 224
             +TR G  + S    +P AV+P     A  TS+       P+  G         P P  P
Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP 1478

Query: 225  PQKGDEADVSSPHP--------GEPNVPKGLADRKQNDQRKVSQGR--LAPRPPPVEKSK 274
            P     A  SSP          G P +P  +    +      S  R  +AP    + K  
Sbjct: 1479 PAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKT 1538

Query: 275  EIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSP 334
               +  KE   P      +PK    +       A     P   E+     +  + ++G+P
Sbjct: 1539 PATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA----TPSSKEASSPPAVTPSTYKGAP 1594

Query: 335  LPRSPTQDAAGVGP-PASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEP 393
             P+      A   P P      PA  P  PE G     P      P +   S    P  P
Sbjct: 1595 SPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSP 1654

Query: 394  GPRLQKVLAKLPLAEEEKRFAGKAGGKLAK----APGLKDFQIQVQPVRMQKLTK 444
                 K+ A +P A   K    K G    K    AP  +   I   P R    TK
Sbjct: 1655 ASVTCKMGATVPQA--SKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTK 1707



 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 61/241 (25%), Positives = 87/241 (36%), Gaps = 49/241 (20%)

Query: 179  DSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGA--PPQ----KGDEAD 232
            DSPS +  ++SP      ++  S    TP G    S P SP+  +  P      +G +  
Sbjct: 792  DSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGN--LSSPVSPVEASFLPENSLSFQGSKDS 849

Query: 233  VSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVE--KSKEIAIEQKENFDP---- 286
             ++ H   P  PKG                 AP P  V     K + +  KE   P    
Sbjct: 850  PATTHSPTPPSPKG-----------------APTPSAVTPLSPKGVTLPPKETPTPSVVN 892

Query: 287  LQYPETTPKGLAP-------VTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSP 339
            L +P+  P   AP       +T+SS K A  +P P  + +    +       G+P P + 
Sbjct: 893  LPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPK-------GAPTPPAA 945

Query: 340  TQDAAGVGP----PASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGP 395
            T  +   GP    P      PA  P  P+ G     P     PP     S   GP  P P
Sbjct: 946  TPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005

Query: 396  R 396
            +
Sbjct: 1006 K 1006



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 54/235 (22%), Positives = 74/235 (31%), Gaps = 28/235 (11%)

Query: 174  RSSPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADV 233
            + SP  +P     +  P+A+P S + +    P P G         P P   P        
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079

Query: 234  SSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPP---PVEKSKEIAIEQKENFDPLQYP 290
             +P    P  PKG               + AP PP   P      +A        P +  
Sbjct: 1080 PTPPAATPPSPKG--------GPATPSPKGAPMPPAATPPSPKGGLAT------PPHKGA 1125

Query: 291  ETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAA------ 344
             TTP    P  +  G +A   P+  P          K G    P   +PT  AA      
Sbjct: 1126 PTTPAATPP--SPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1183

Query: 345  -GVGPPASQG--RGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPR 396
             G+  P+ +G    PA  P  P+ G     P      P     S   G   P P+
Sbjct: 1184 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1238



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 100/407 (24%), Positives = 131/407 (32%), Gaps = 79/407 (19%)

Query: 16   GAQASWSIFGAD---AAEVPGTRGHSQQEAAM-PHIPEDEEPPGEPQAAQSPAGQGPPTA 71
            G  A+ S+ GA    AA  P  +G     +     +P    PP       +P  +G PT 
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128

Query: 72   GVSCSPTPTIVLTGDATSPEGETDKNLANRVHSPHKRLSHRHLK--VSTASLTSVDPAGH 129
              +  P+P     G AT P        A    SP   L+    K   +T + T   P G 
Sbjct: 1129 PAATPPSPK---GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1185

Query: 130  IIDLVNDQLPDISISEEDKKKNLALLEEAKLVSERFLTRRGRKSRSSPGDSPSAVSPNLS 189
            +        P    +     K                   G  +  SP  +P+      +
Sbjct: 1186 LATPSPKGAPTTPAATPPSPK-------------------GGLATPSPKGAPT------T 1220

Query: 190  PSASPTSSRSNSLTVPTPPGLDV--CSGPPSPL--PGAPPQKGDEAD------------V 233
            P+A+P S +   L  P+P G      + PPSP   P  PP KG                 
Sbjct: 1221 PAATPPSPK-GGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLA 1279

Query: 234  SSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETT 293
            + PH G PN P  +           S  + AP PP                 P   P T 
Sbjct: 1280 TPPHKGAPN-PAVVTPPSPKGGPATSPPKGAPTPPAATPP-----------SPKGSPGTP 1327

Query: 294  PKGLAP----VTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPP 349
            P   AP    VT  S K     P   P  S  G     +  EG      PT  AA    P
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPATTP--SSKGGPTTPSSKEG------PTPPAA---TP 1376

Query: 350  ASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPR 396
            + +G GPA  P  P+ G     P      P +  LS    P  P  R
Sbjct: 1377 SHKG-GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTR 1422



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 93/388 (23%), Positives = 126/388 (32%), Gaps = 67/388 (17%)

Query: 51   EEPPGEPQAAQSPAGQGPPTAGVSCSPTPTIVLTGDATSP-EGETDKNLANRVHSPHKRL 109
            E P   P  +  PAG  P T  V    + T  L   A+SP E  T+ + A+   S    L
Sbjct: 729  EIPKSVPSPSLPPAGTPPGTKKVD-GISHTSALAPVASSPKECPTEDSGASATASSKGTL 787

Query: 110  SH-----RHLKVSTASLTSVDPAGHIIDLVNDQLPDISISEEDKKKNLALLEEAKLVSER 164
            ++       L VS +  T   P            PD  I       +     EA  + E 
Sbjct: 788  TYLADSPSPLGVSVSPQTKRPPTKK-----GSAGPDTPIGNLSSPVSPV---EASFLPEN 839

Query: 165  FLTRRGRKSRSSPGDSPSAVSPNLSPSAS---PTSSRSNSL---TVPTP----------- 207
             L+ +G K   +   SP+  SP  +P+ S   P S +  +L     PTP           
Sbjct: 840  SLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG 899

Query: 208  ---------PGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKV 258
                     P L + S  P      P  KG  A   SP P     P              
Sbjct: 900  PATPAPKQAPALSMTSSSPKKARATPAPKGIPA---SPSPKGAPTPPAATPPSPKGGPAT 956

Query: 259  SQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPET-TPKG-----LAPVTNSSGKMALNSP 312
               + AP PP                 P   P T +PKG      A   +  G  A  SP
Sbjct: 957  PSPKWAPTPPAATPP-----------SPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005

Query: 313  QPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPM--GPEAGSKAE 370
            +  P    +     K     +P P+  +   A   PP+ +G  PA  P+  G      A 
Sbjct: 1006 KGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT-PPSPKG-SPAATPLPKGAPTTPAAT 1063

Query: 371  LPPTVSRP--PLLRGLSWDSGPEEPGPR 396
            LP     P  P L+G         P P+
Sbjct: 1064 LPSPKGGPATPSLKGAPTPPAATPPSPK 1091


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 97/401 (24%), Positives = 133/401 (33%), Gaps = 59/401 (14%)

Query: 27  DAAEVPGTRGHSQQEAA--MPHIPEDEEPPGE----PQAAQSPAGQGPPTAGVSCSPTPT 80
           D    P T   +  EAA  +   P  + PP      P   Q P  Q PP A     PTP 
Sbjct: 600 DGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQA-----PTPQ 654

Query: 81  IVLTGDATSPEGETDKNLANRVHSPHKRLSHRHLKVSTASLTSVDPAGHIIDLVNDQLPD 140
                 AT+P+             P   L+    K+      S  P      L  D L  
Sbjct: 655 AAAPPQATTPQ-------------PSPGLASSPEKIVLGQPPSATPTAI---LTQDSL-Q 697

Query: 141 ISISEEDKKKNLALLEEAKLVSERFLTRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSN 200
           + + +E  ++ L+       V    +      ++     +P A    L P A    S+++
Sbjct: 698 MFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAP--DSQAS 755

Query: 201 SLTVPTPPGLDVCSGP-PSPLPGAPPQK--GDEADVSSPHPGEPNVPKGLADRKQNDQRK 257
               P  P      GP PS  P  P Q   GD   + SPHP  P  P     R Q+  R 
Sbjct: 756 PAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRP--PSRPPSRPQSVSRP 813

Query: 258 VSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPV 317
            S+  L P PPP        I   +N   +  P + P   AP          + P  GP+
Sbjct: 814 PSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPL 873

Query: 318 ESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPP---- 373
                            LP S T  A       S  R PA  P    +  + + PP    
Sbjct: 874 P------------PAPHLPPSSTSSAVASSSETS-SRLPAPTP----SDFQLQFPPSQGP 916

Query: 374 --TVSRPPLLRGLSWDSGPEEPGPR-LQKVLAKLPLAEEEK 411
             + + PP L  +   + P  P PR  Q V    P   + K
Sbjct: 917 HKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPK 957



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 103/460 (22%), Positives = 154/460 (33%), Gaps = 103/460 (22%)

Query: 48   PEDEEPPGEP--QAAQSPAGQGP-PTAGVSCSP-----------TPTIVLTGDATS---P 90
            P+ ++PP  P  QAA  P    P P+ G++ SP           TPT +LT D+     P
Sbjct: 642  PQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLP 701

Query: 91   EGETDKNLANRVHSPHKRLSHRHLKVSTASLTSVDPAGHIIDL----VNDQLPDISISEE 146
            +  + + L+     PH  LS     + +A   + DPA          +  Q PD   S  
Sbjct: 702  QERSQQPLS--AEGPH--LSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPA 757

Query: 147  DKKKNLALLEEAKLVSERFLTRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSLT--- 203
               +  A    A L      +      ++  GDSP   SP+ +   S   SR  S++   
Sbjct: 758  PAPQIPAA---APLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPP 814

Query: 204  -------------VPTPPGLDVCSG------------PPSPLPGAPPQKGDEADVSSPHP 238
                          PT PG+ V               P +P P  PP +        P P
Sbjct: 815  SEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLP 874

Query: 239  GEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLA 298
              P++P            + S    AP P   +            F P Q P  +P    
Sbjct: 875  PAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQL----------QFPPSQGPHKSPTP-P 923

Query: 299  PVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRS--------PT----QDAAGV 346
            P  +   + A  +P P P  +    Q++ T +   P P++        P+    Q+ AG 
Sbjct: 924  PTLHLVPEPA--APPPPPPRT---FQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGG 978

Query: 347  GPPASQ------------------GRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDS 388
             P A Q                  G+ P+G P  P              PPLL   +   
Sbjct: 979  APAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAF 1038

Query: 389  GPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKAPGLK 428
                P   + K  +  P      ++  K  G L K P L+
Sbjct: 1039 ASNLPTLNVAKAASSGPGKPSGLQYESKLSG-LKKPPTLQ 1077



 Score = 33.5 bits (75), Expect = 0.92
 Identities = 45/184 (24%), Positives = 59/184 (32%), Gaps = 54/184 (29%)

Query: 205  PTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLA 264
            P P  L V   PP P P  PP       V  P P  P            +++ +      
Sbjct: 1335 PPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAP------------ERKPLGTAPHC 1382

Query: 265  PRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGP-------- 316
            PR P       +    +EN      PE TP         +G+    SP P P        
Sbjct: 1383 PRLP-------LRKTYRENVGGPGAPEGTP---------AGRARGGSPAPLPAKVDEATS 1426

Query: 317  --------VESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSK 368
                    VE EL +++LK      P P      A G G P  +  G     + P    K
Sbjct: 1427 GLIRELAAVEDELYQRMLK-----GPPPEPAASAAQGTGDPDWEAPG-----LPPAKRRK 1476

Query: 369  AELP 372
            +E P
Sbjct: 1477 SESP 1480



 Score = 30.8 bits (68), Expect = 5.9
 Identities = 68/252 (26%), Positives = 86/252 (34%), Gaps = 38/252 (15%)

Query: 178  GDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPH 237
            G SPS      S S S +SS S++ +      LD     P P    PP K  EA      
Sbjct: 1254 GGSPSVTWARASSSLSSSSSSSSAAS-----SLDADEDGPMPSRNRPPIKTYEARSRIGL 1308

Query: 238  PGEPNVPKGLADRKQNDQRKVSQGRLAP--RPPPVEKSKEIAIEQKENFDPLQYPETTPK 295
              +     GL+       + V    L P  +PPP   + ++A       +P   P   P 
Sbjct: 1309 KLKIKQEAGLS-------KVVHNTALDPVHQPPPPPATLKVA-------EPPPRPPPPP- 1353

Query: 296  GLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRG 355
               P T        + P   P    LG     T      LP   T      GP A +G  
Sbjct: 1354 ---PPTGQMNGTVDHPPPAAPERKPLG-----TAPHCPRLPLRKTYRENVGGPGAPEGT- 1404

Query: 356  PAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAG 415
            PAG   G   GS A LP  V       GL  +    E    L + + K P  E     A 
Sbjct: 1405 PAGRARG---GSPAPLPAKVDE--ATSGLIRELAAVE--DELYQRMLKGPPPEPAASAAQ 1457

Query: 416  KAGGKLAKAPGL 427
              G    +APGL
Sbjct: 1458 GTGDPDWEAPGL 1469


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 59/244 (24%), Positives = 87/244 (35%), Gaps = 33/244 (13%)

Query: 180 SPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAP--PQKGDEADVSSPH 237
           +P A +PN     +PT+ +  + T P  P       P +P   AP  P+      +  P 
Sbjct: 534 TPKAAAPNTPKEPAPTTPKEPAPTTPKEP------APTTPKETAPTTPKGTAPTTLKEPA 587

Query: 238 PGEPN--VPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPK 295
           P  P    PK LA     +    +  + AP  P  + +     ++     P +   TTPK
Sbjct: 588 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP--KGTAPTTPKEPAPTTPKEPAPTTPK 645

Query: 296 GLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEG-------SPLPRSPTQDAAGV-- 346
           G AP T       L  P P   +    K+L  T  +G        P P +P + A     
Sbjct: 646 GTAPTT-------LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 698

Query: 347 --GPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPE---EPGPRLQKVL 401
              P   +   P      P   S+   P T   P  +     +S PE   EP P+  +  
Sbjct: 699 EPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENS 758

Query: 402 AKLP 405
            K P
Sbjct: 759 PKEP 762



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 55/227 (24%), Positives = 84/227 (37%), Gaps = 26/227 (11%)

Query: 167 TRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSLT-----VPTPPGLDVCSGPPSPLP 221
           T+    +   P  + +  +P      SPT+++  + T      PT P     + P  P P
Sbjct: 393 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 452

Query: 222 GAP----PQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIA 277
             P    P    +   ++P    P  PK  A          +  +LAP  P  EK     
Sbjct: 453 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP--EKPAPTT 510

Query: 278 IEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSP-QPGPVESELGKQLLKTGWEGSPLP 336
            E+     P +   TTP+  AP T  +   A N+P +P P      K+   T     P P
Sbjct: 511 PEELAPTTPEEPTPTTPEEPAPTTPKAA--APNTPKEPAPTTP---KEPAPT-TPKEPAP 564

Query: 337 RSPTQDAAGVGPPASQGRGPA----GEPMGPEAGSKAELPPTVSRPP 379
            +P + A    P   +G  P       P  P+  +  EL PT ++ P
Sbjct: 565 TTPKETA----PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 607



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 52/228 (22%), Positives = 75/228 (32%), Gaps = 32/228 (14%)

Query: 177 PGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSP 236
           P  + +  +P      +PT+ +  + T P  P       P    P  P     E   ++P
Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 345

Query: 237 HPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKG 296
               P  PK  A                P+ P     KE A    +   P     TTPK 
Sbjct: 346 KEPAPTAPKKPAP-------------TTPKEPAPTTPKEPAPTTTKEPSP-----TTPKE 387

Query: 297 LAPVTNSSGKMALNSPQPGPVES--ELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGR 354
            AP T  S       P P   +S     K+   T  +  P P +P + A     P +  +
Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK-EPAPTTPKEPA-----PTTPKK 441

Query: 355 GPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLA 402
                P  P   +  E  PT ++ P        + P+EP P   K  A
Sbjct: 442 PAPTTPKEPAPTTPKEPAPTTTKKPA------PTTPKEPAPTTPKETA 483



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 52/221 (23%), Positives = 70/221 (31%), Gaps = 22/221 (9%)

Query: 181 PSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGE 240
           P++ +P      +PT+ +S   T   P      S P +P   AP           P P  
Sbjct: 224 PASTTPK---EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP------TTTKEPAPTT 274

Query: 241 PNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKE--NFDPLQYPETTPKGLA 298
           P  P     ++       S       P P    K      KE     P +   TTPK  A
Sbjct: 275 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 334

Query: 299 PVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAG 358
           P T          P P   +    K    T  E  P P +P + A    P  ++   P  
Sbjct: 335 PTTKEPAPTTPKEPAPTAPK----KPAPTTPKE--PAPTTPKEPA----PTTTKEPSPT- 383

Query: 359 EPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQK 399
            P  P   +    P T   P      S  + P+EP P   K
Sbjct: 384 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 424


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 59/244 (24%), Positives = 87/244 (35%), Gaps = 33/244 (13%)

Query: 180 SPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAP--PQKGDEADVSSPH 237
           +P A +PN     +PT+ +  + T P  P       P +P   AP  P+      +  P 
Sbjct: 575 TPKAAAPNTPKEPAPTTPKEPAPTTPKEP------APTTPKETAPTTPKGTAPTTLKEPA 628

Query: 238 PGEPN--VPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPK 295
           P  P    PK LA     +    +  + AP  P  + +     ++     P +   TTPK
Sbjct: 629 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP--KGTAPTTPKEPAPTTPKEPAPTTPK 686

Query: 296 GLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEG-------SPLPRSPTQDAAGV-- 346
           G AP T       L  P P   +    K+L  T  +G        P P +P + A     
Sbjct: 687 GTAPTT-------LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 739

Query: 347 --GPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPE---EPGPRLQKVL 401
              P   +   P      P   S+   P T   P  +     +S PE   EP P+  +  
Sbjct: 740 EPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENS 799

Query: 402 AKLP 405
            K P
Sbjct: 800 PKEP 803



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 55/227 (24%), Positives = 84/227 (37%), Gaps = 26/227 (11%)

Query: 167 TRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSLT-----VPTPPGLDVCSGPPSPLP 221
           T+    +   P  + +  +P      SPT+++  + T      PT P     + P  P P
Sbjct: 434 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 493

Query: 222 GAP----PQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIA 277
             P    P    +   ++P    P  PK  A          +  +LAP  P  EK     
Sbjct: 494 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP--EKPAPTT 551

Query: 278 IEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSP-QPGPVESELGKQLLKTGWEGSPLP 336
            E+     P +   TTP+  AP T  +   A N+P +P P      K+   T     P P
Sbjct: 552 PEELAPTTPEEPTPTTPEEPAPTTPKAA--APNTPKEPAPTTP---KEPAPT-TPKEPAP 605

Query: 337 RSPTQDAAGVGPPASQGRGPA----GEPMGPEAGSKAELPPTVSRPP 379
            +P + A    P   +G  P       P  P+  +  EL PT ++ P
Sbjct: 606 TTPKETA----PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 648



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 52/228 (22%), Positives = 75/228 (32%), Gaps = 32/228 (14%)

Query: 177 PGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSP 236
           P  + +  +P      +PT+ +  + T P  P       P    P  P     E   ++P
Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 386

Query: 237 HPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKG 296
               P  PK  A                P+ P     KE A    +   P     TTPK 
Sbjct: 387 KEPAPTAPKKPAP-------------TTPKEPAPTTPKEPAPTTTKEPSP-----TTPKE 428

Query: 297 LAPVTNSSGKMALNSPQPGPVES--ELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGR 354
            AP T  S       P P   +S     K+   T  +  P P +P + A     P +  +
Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK-EPAPTTPKEPA-----PTTPKK 482

Query: 355 GPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLA 402
                P  P   +  E  PT ++ P        + P+EP P   K  A
Sbjct: 483 PAPTTPKEPAPTTPKEPAPTTTKKPA------PTTPKEPAPTTPKETA 524



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 52/221 (23%), Positives = 70/221 (31%), Gaps = 22/221 (9%)

Query: 181 PSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGE 240
           P++ +P      +PT+ +S   T   P      S P +P   AP           P P  
Sbjct: 265 PASTTPK---EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP------TTTKEPAPTT 315

Query: 241 PNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKE--NFDPLQYPETTPKGLA 298
           P  P     ++       S       P P    K      KE     P +   TTPK  A
Sbjct: 316 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 375

Query: 299 PVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAG 358
           P T          P P   +    K    T  E  P P +P + A    P  ++   P  
Sbjct: 376 PTTKEPAPTTPKEPAPTAPK----KPAPTTPKE--PAPTTPKEPA----PTTTKEPSPT- 424

Query: 359 EPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQK 399
            P  P   +    P T   P      S  + P+EP P   K
Sbjct: 425 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 465


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 59/244 (24%), Positives = 87/244 (35%), Gaps = 33/244 (13%)

Query: 180 SPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAP--PQKGDEADVSSPH 237
           +P A +PN     +PT+ +  + T P  P       P +P   AP  P+      +  P 
Sbjct: 627 TPKAAAPNTPKEPAPTTPKEPAPTTPKEP------APTTPKETAPTTPKGTAPTTLKEPA 680

Query: 238 PGEPN--VPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPK 295
           P  P    PK LA     +    +  + AP  P  + +     ++     P +   TTPK
Sbjct: 681 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP--KGTAPTTPKEPAPTTPKEPAPTTPK 738

Query: 296 GLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEG-------SPLPRSPTQDAAGV-- 346
           G AP T       L  P P   +    K+L  T  +G        P P +P + A     
Sbjct: 739 GTAPTT-------LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 791

Query: 347 --GPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPE---EPGPRLQKVL 401
              P   +   P      P   S+   P T   P  +     +S PE   EP P+  +  
Sbjct: 792 EPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENS 851

Query: 402 AKLP 405
            K P
Sbjct: 852 PKEP 855



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 55/227 (24%), Positives = 84/227 (37%), Gaps = 26/227 (11%)

Query: 167 TRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSLT-----VPTPPGLDVCSGPPSPLP 221
           T+    +   P  + +  +P      SPT+++  + T      PT P     + P  P P
Sbjct: 486 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 545

Query: 222 GAP----PQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIA 277
             P    P    +   ++P    P  PK  A          +  +LAP  P  EK     
Sbjct: 546 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP--EKPAPTT 603

Query: 278 IEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSP-QPGPVESELGKQLLKTGWEGSPLP 336
            E+     P +   TTP+  AP T  +   A N+P +P P      K+   T     P P
Sbjct: 604 PEELAPTTPEEPTPTTPEEPAPTTPKAA--APNTPKEPAPTTP---KEPAPT-TPKEPAP 657

Query: 337 RSPTQDAAGVGPPASQGRGPA----GEPMGPEAGSKAELPPTVSRPP 379
            +P + A    P   +G  P       P  P+  +  EL PT ++ P
Sbjct: 658 TTPKETA----PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 700



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 52/228 (22%), Positives = 75/228 (32%), Gaps = 32/228 (14%)

Query: 177 PGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSP 236
           P  + +  +P      +PT+ +  + T P  P       P    P  P     E   ++P
Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 438

Query: 237 HPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKG 296
               P  PK  A                P+ P     KE A    +   P     TTPK 
Sbjct: 439 KEPAPTAPKKPAP-------------TTPKEPAPTTPKEPAPTTTKEPSP-----TTPKE 480

Query: 297 LAPVTNSSGKMALNSPQPGPVES--ELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGR 354
            AP T  S       P P   +S     K+   T  +  P P +P + A     P +  +
Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK-EPAPTTPKEPA-----PTTPKK 534

Query: 355 GPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLA 402
                P  P   +  E  PT ++ P        + P+EP P   K  A
Sbjct: 535 PAPTTPKEPAPTTPKEPAPTTTKKPA------PTTPKEPAPTTPKETA 576



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 52/221 (23%), Positives = 70/221 (31%), Gaps = 22/221 (9%)

Query: 181 PSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGE 240
           P++ +P      +PT+ +S   T   P      S P +P   AP           P P  
Sbjct: 317 PASTTPK---EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP------TTTKEPAPTT 367

Query: 241 PNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKE--NFDPLQYPETTPKGLA 298
           P  P     ++       S       P P    K      KE     P +   TTPK  A
Sbjct: 368 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 427

Query: 299 PVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAG 358
           P T          P P   +    K    T  E  P P +P + A    P  ++   P  
Sbjct: 428 PTTKEPAPTTPKEPAPTAPK----KPAPTTPKE--PAPTTPKEPA----PTTTKEPSPT- 476

Query: 359 EPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQK 399
            P  P   +    P T   P      S  + P+EP P   K
Sbjct: 477 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 517



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 39/198 (19%), Positives = 78/198 (39%), Gaps = 15/198 (7%)

Query: 633 NLKRTYEKDHAELMEFKKLANQNSSRSCGPSEDGVPRTARSMSLTLGKNMPRRRVSVAVV 692
           N K+T +   +E +  +   ++N   S   S      T R +  +   +   R +   + 
Sbjct: 100 NKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKN-SAANRELQKKLK 158

Query: 693 PKFNALNLPGQTPSSSSIPSLPALSESPNG--KGSLPVTSALPALLENGKTNGDPDCEAS 750
            K N  N   + P+    P  P + E+ +G   G   VT+   +  ++ K +  P    +
Sbjct: 159 VKDNKKNRTKKKPT----PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA 214

Query: 751 APALTLSCL---EELSQETKARMEEEAYSKGFQEGLKKTKELQDLKEEEEEQKSESPEEP 807
            P      L    + S+ET   + +E   +      K+T         + ++K+ S +E 
Sbjct: 215 KPINPRPSLPPNSDTSKETSLTVNKETTVE-----TKETTTTNKQTSTDGKEKTTSAKET 269

Query: 808 EEVEETEEEEKGPRSSKL 825
           + +E+T  ++  P S  L
Sbjct: 270 QSIEKTSAKDLAPTSKVL 287


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 59/244 (24%), Positives = 87/244 (35%), Gaps = 33/244 (13%)

Query: 180 SPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAP--PQKGDEADVSSPH 237
           +P A +PN     +PT+ +  + T P  P       P +P   AP  P+      +  P 
Sbjct: 668 TPKAAAPNTPKEPAPTTPKEPAPTTPKEP------APTTPKETAPTTPKGTAPTTLKEPA 721

Query: 238 PGEPN--VPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPK 295
           P  P    PK LA     +    +  + AP  P  + +     ++     P +   TTPK
Sbjct: 722 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP--KGTAPTTPKEPAPTTPKEPAPTTPK 779

Query: 296 GLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEG-------SPLPRSPTQDAAGV-- 346
           G AP T       L  P P   +    K+L  T  +G        P P +P + A     
Sbjct: 780 GTAPTT-------LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 832

Query: 347 --GPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPE---EPGPRLQKVL 401
              P   +   P      P   S+   P T   P  +     +S PE   EP P+  +  
Sbjct: 833 EPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENS 892

Query: 402 AKLP 405
            K P
Sbjct: 893 PKEP 896



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 55/227 (24%), Positives = 84/227 (37%), Gaps = 26/227 (11%)

Query: 167 TRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSLT-----VPTPPGLDVCSGPPSPLP 221
           T+    +   P  + +  +P      SPT+++  + T      PT P     + P  P P
Sbjct: 527 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 586

Query: 222 GAP----PQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIA 277
             P    P    +   ++P    P  PK  A          +  +LAP  P  EK     
Sbjct: 587 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP--EKPAPTT 644

Query: 278 IEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSP-QPGPVESELGKQLLKTGWEGSPLP 336
            E+     P +   TTP+  AP T  +   A N+P +P P      K+   T     P P
Sbjct: 645 PEELAPTTPEEPTPTTPEEPAPTTPKAA--APNTPKEPAPTTP---KEPAPT-TPKEPAP 698

Query: 337 RSPTQDAAGVGPPASQGRGPA----GEPMGPEAGSKAELPPTVSRPP 379
            +P + A    P   +G  P       P  P+  +  EL PT ++ P
Sbjct: 699 TTPKETA----PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 741



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 52/228 (22%), Positives = 75/228 (32%), Gaps = 32/228 (14%)

Query: 177 PGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSP 236
           P  + +  +P      +PT+ +  + T P  P       P    P  P     E   ++P
Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 479

Query: 237 HPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKG 296
               P  PK  A                P+ P     KE A    +   P     TTPK 
Sbjct: 480 KEPAPTAPKKPAP-------------TTPKEPAPTTPKEPAPTTTKEPSP-----TTPKE 521

Query: 297 LAPVTNSSGKMALNSPQPGPVES--ELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGR 354
            AP T  S       P P   +S     K+   T  +  P P +P + A     P +  +
Sbjct: 522 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK-EPAPTTPKEPA-----PTTPKK 575

Query: 355 GPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLA 402
                P  P   +  E  PT ++ P        + P+EP P   K  A
Sbjct: 576 PAPTTPKEPAPTTPKEPAPTTTKKPA------PTTPKEPAPTTPKETA 617



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 52/221 (23%), Positives = 70/221 (31%), Gaps = 22/221 (9%)

Query: 181 PSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGE 240
           P++ +P      +PT+ +S   T   P      S P +P   AP           P P  
Sbjct: 358 PASTTPK---EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP------TTTKEPAPTT 408

Query: 241 PNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKE--NFDPLQYPETTPKGLA 298
           P  P     ++       S       P P    K      KE     P +   TTPK  A
Sbjct: 409 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 468

Query: 299 PVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAG 358
           P T          P P   +    K    T  E  P P +P + A    P  ++   P  
Sbjct: 469 PTTKEPAPTTPKEPAPTAPK----KPAPTTPKE--PAPTTPKEPA----PTTTKEPSPT- 517

Query: 359 EPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQK 399
            P  P   +    P T   P      S  + P+EP P   K
Sbjct: 518 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 558



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 39/198 (19%), Positives = 78/198 (39%), Gaps = 15/198 (7%)

Query: 633 NLKRTYEKDHAELMEFKKLANQNSSRSCGPSEDGVPRTARSMSLTLGKNMPRRRVSVAVV 692
           N K+T +   +E +  +   ++N   S   S      T R +  +   +   R +   + 
Sbjct: 141 NKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKN-SAANRELQKKLK 199

Query: 693 PKFNALNLPGQTPSSSSIPSLPALSESPNG--KGSLPVTSALPALLENGKTNGDPDCEAS 750
            K N  N   + P+    P  P + E+ +G   G   VT+   +  ++ K +  P    +
Sbjct: 200 VKDNKKNRTKKKPT----PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA 255

Query: 751 APALTLSCL---EELSQETKARMEEEAYSKGFQEGLKKTKELQDLKEEEEEQKSESPEEP 807
            P      L    + S+ET   + +E   +      K+T         + ++K+ S +E 
Sbjct: 256 KPINPRPSLPPNSDTSKETSLTVNKETTVE-----TKETTTTNKQTSTDGKEKTTSAKET 310

Query: 808 EEVEETEEEEKGPRSSKL 825
           + +E+T  ++  P S  L
Sbjct: 311 QSIEKTSAKDLAPTSKVL 328


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 73/294 (24%), Positives = 104/294 (35%), Gaps = 61/294 (20%)

Query: 120 SLTSVDPAGHIIDLVNDQLPDISISEEDKKKNLALLEEAKLVSE--RFLTRRGRKSRSSP 177
           +L   D   HII++V   +P I   +++ K+ +  L   K+     R   R     R S 
Sbjct: 374 ALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPRQRQRDASPGRGSH 433

Query: 178 GDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGA-----------PPQ 226
           G +PS  +  L    S   +   +   P P G     GPP P PG            PPQ
Sbjct: 434 GQTPSPGALPLGRQTSQQPAGPPAQQRPPPQG-----GPPQPGPGPQRQGPPLQQRPPPQ 488

Query: 227 KGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQ--------GRLA------PRPPPVEK 272
                    P  G P +P+ L       Q+  SQ        GR +      P  PP  +
Sbjct: 489 GQQHLSGLGPPAGSP-LPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAAR 547

Query: 273 SKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEG 332
                  Q++   P    +T+  G AP   +SG       + GP +   G          
Sbjct: 548 PPASPSPQRQAGPPQATRQTSVSGPAP-PKASGAPPGGQQRQGPPQKPPG---------- 596

Query: 333 SPLPRSPTQDAAGVGP-----------PASQGRGPAGEPMGPEAGSK--AELPP 373
              P  PT+ A+  GP           P   G GPAG P  P+   K   ++PP
Sbjct: 597 ---PAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPK-PQLAQKPSQDVPP 646



 Score = 38.1 bits (87), Expect = 0.037
 Identities = 30/109 (27%), Positives = 43/109 (39%), Gaps = 22/109 (20%)

Query: 271 EKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGW 330
           ++ K++ +E   N      P    +  +P   S G+    +P PG +             
Sbjct: 400 DEDKQLIVELVVNKMAQALPRQRQRDASPGRGSHGQ----TPSPGAL------------- 442

Query: 331 EGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPP 379
              PL R  +Q  AG  PPA Q   P G P  P  G + + PP   RPP
Sbjct: 443 ---PLGRQTSQQPAG--PPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPP 486



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 51/198 (25%), Positives = 73/198 (36%), Gaps = 25/198 (12%)

Query: 178 GDSPSAVSPNLSPSASPTSSRSNSLTVPTPP--GLDVCSGPPSPLPGAPPQKGDEADVSS 235
           G  P A SP      SPTS+     +   PP  G    S P +  PGAPP        ++
Sbjct: 495 GLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPP--------AA 546

Query: 236 PHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPK 295
             P  P+  +     +   Q  VS     P PP    +     ++       Q P   P 
Sbjct: 547 RPPASPSPQRQAGPPQATRQTSVS----GPAPPKASGAPPGGQQR-------QGPPQKPP 595

Query: 296 GLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRG 355
           G A  T  + + A   P+ GP  ++  +     G  G P P+   + +  V PPA+   G
Sbjct: 596 GPAGPTRQASQ-AGPVPRTGPPTTQQPRP-SGPGPAGRPKPQLAQKPSQDVPPPATAAAG 653

Query: 356 PAGEPMGPEAGSKAELPP 373
             G P      S A+  P
Sbjct: 654 --GPPHPQLKASPAQAQP 669


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 58/212 (27%), Positives = 72/212 (33%), Gaps = 24/212 (11%)

Query: 177 PGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSP--LPGAPPQKGDEADVS 234
           P   P    P    S SP S        P P G +   GPP P   P  PP +G +    
Sbjct: 134 PPGKPQGPPPQGDKSRSPRSPPGKPQG-PPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQG 192

Query: 235 SPHPGEPNVPKGLADRKQNDQRKVS-------QGRLAPRPPPVEKSKEIAIEQKENFDPL 287
            P PG+P  P    D+ ++ Q           QG   P+ PP    K           P 
Sbjct: 193 PPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQG--------PP 244

Query: 288 QYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVG 347
                 P+G  P     G  A    +     S  GK       EG+  P+ P   A   G
Sbjct: 245 PQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNN-PQGPPPPAG--G 301

Query: 348 PPASQGRGPAGEPMGPEAGSKAELPPTVSRPP 379
            P      PAG+P GP    +   P   SRPP
Sbjct: 302 NPQQPQAPPAGQPQGPPRPPQGGRP---SRPP 330



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 68/265 (25%), Positives = 91/265 (34%), Gaps = 23/265 (8%)

Query: 177 PGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSP--LPGAPPQKGDEADVS 234
           P   P    P    S SP S        P P G +   GPP P   P  PP +G      
Sbjct: 73  PPGKPQGPPPQGDKSRSPRSPPGKPQG-PPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQG 131

Query: 235 SPHPGEPNVPKGLADRKQND-------QRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPL 287
            P PG+P  P    D+ ++        Q    QG   P+ PP    K      +    P 
Sbjct: 132 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQ 191

Query: 288 QYPET-TPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGV 346
             P    P+G  P  + S        +P     + G Q      +G P P    Q     
Sbjct: 192 GPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQP-----QGPPPPPGKPQGPPPQ 246

Query: 347 GPPASQGRGPAGEPMGPEA--GSKAEL----PPTVSRPPLLRGLSWDSGPEEPGPRLQKV 400
           G    QG  P G+P GP A  GSK++     P     PP   G +    P   G   Q+ 
Sbjct: 247 GGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 306

Query: 401 LAKLPLAEEEKRFAGKAGGKLAKAP 425
            A  P  + +       GG+ ++ P
Sbjct: 307 QAP-PAGQPQGPPRPPQGGRPSRPP 330



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 60/241 (24%), Positives = 77/241 (31%), Gaps = 29/241 (12%)

Query: 178 GDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGL--------DVCSGPPSPL---PGAPPQ 226
           G+ P    P       P     N    P PPG         D    P SP     G PPQ
Sbjct: 44  GNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQ 103

Query: 227 KGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDP 286
            G++     P PG+P  P      +   Q     G+    PP  +KS+       +   P
Sbjct: 104 GGNQPQGPPPPPGKPQGPPPQGGNR--PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 161

Query: 287 LQYPETTPKGLAPVTN-------SSGKMALNSPQPGPVES---ELGKQLLKTGWEGSPLP 336
                  P+G  P            GK     P PG  +    +  K        G P  
Sbjct: 162 PPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQG 221

Query: 337 RSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSR---PPLLRGLSWDSGPEEP 393
             P       GPP   G+ P G P  P+ G+K + PP   +   PP   G    S    P
Sbjct: 222 PPPQGGNQPQGPPPPPGK-PQGPP--PQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPP 278

Query: 394 G 394
           G
Sbjct: 279 G 279



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 48/187 (25%), Positives = 68/187 (36%), Gaps = 27/187 (14%)

Query: 217 PSPLPGAP----PQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEK 272
           PS + G P    PQ G++     P PG+P  P               QG   P+ PP   
Sbjct: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPP-------------PQGGNKPQGPPPPG 75

Query: 273 SKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEG 332
             +    Q +     + P   P+G  P     G      P P P + +          +G
Sbjct: 76  KPQGPPPQGDKSRSPRSPPGKPQGPPP----QGGNQPQGPPPPPGKPQGPPPQGGNRPQG 131

Query: 333 SPLPRSPTQDAAGVGPPASQGRGPAGEPMG--PEAGSKAE-LPPTVSRP--PLLRGLSWD 387
            P P  P Q     G  +   R P G+P G  P+ G++ +  PP   +P  P  +G    
Sbjct: 132 PPPPGKP-QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKP 190

Query: 388 SGPEEPG 394
            GP  PG
Sbjct: 191 QGPPPPG 197


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 128/610 (20%), Positives = 218/610 (35%), Gaps = 87/610 (14%)

Query: 132  DLVNDQLPDISISEEDKKKNLALL--EEAKLVSERFLTRRGRKSRSSPGDS--PSAVSPN 187
            D ++ +   I+  ++D +  ++ L  E AKL  E    ++   S S+   +  PS  S  
Sbjct: 512  DALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRA 571

Query: 188  LSPSASPTSSRSNSLTVPTP-PGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGEPNVPKG 246
              P A P    S ++  P P PG      PP P P  PP       +SSP    P++P G
Sbjct: 572  PVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP----PSLPGG 627

Query: 247  LADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGK 306
             A    +    +S     P PPP+ +   I         P   P  T     P    S +
Sbjct: 628  TAI---SPPPPLSGDATIPPPPPLPEGVGIP-------SPSSLPGGTAIPPPPPLPGSAR 677

Query: 307  MALNSPQPGPVESELG---KQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGP 363
            +    P P P+    G         G  G P P  P     G+ PP     GP   P  P
Sbjct: 678  IP---PPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP 734

Query: 364  EAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAK 423
              G    +PP    PP   G    + P  P     K L K  +      ++      L++
Sbjct: 735  GMG----MPPP---PPF--GFGVPAAPVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQ 785

Query: 424  APGLKDFQIQVQPVRMQKLTKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELSPAI 483
                  F  +V+  R +      +  +    Q        D  E  E++K +  +    +
Sbjct: 786  ----DCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKAKKD-QEGGEEKKSVQKKKVKEL 840

Query: 484  EEEESKSGLDVMPNISDVLLRKLRVHR-SLPGSAPPLTEKEVENVFVQL-------SLAF 535
            +  +SK+  ++   +    +    +    L  +   LTE  ++N+  Q+        L+ 
Sbjct: 841  KVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSE 900

Query: 536  RNDSY-----------------TLESRINQAERERNLTEENTEKELENFKASITSSASLW 578
              D Y                  L  R+N       L +    +++EN K  I S  +  
Sbjct: 901  LKDEYDDLAESEQFGVVMGTVPRLRPRLNAI-----LFKLQFSEQVENIKPEIVSVTAAC 955

Query: 579  HHCEHRETYQKLLEDIAVLHRLAARLSSRAEVVG---AVRQEKRMSKATEVMMQYVENLK 635
                  E++  LLE   ++       S  A   G   +   + R +K+T+  M  +  L 
Sbjct: 956  EELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLA 1015

Query: 636  RTYEKDHAELMEF-KKLANQNSSRSCGPSEDGVPRTARSMSLTLGKNMPRRRVSVAVVPK 694
               E D+ ++++F  +LA+             V + +R  +  L KN+ + +  ++ V +
Sbjct: 1016 ELCENDYPDVLKFPDELAH-------------VEKASRVSAENLQKNLDQMKKQISDVER 1062

Query: 695  FNALNLPGQT 704
             +  N P  T
Sbjct: 1063 -DVQNFPAAT 1071


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 128/610 (20%), Positives = 218/610 (35%), Gaps = 87/610 (14%)

Query: 132  DLVNDQLPDISISEEDKKKNLALL--EEAKLVSERFLTRRGRKSRSSPGDS--PSAVSPN 187
            D ++ +   I+  ++D +  ++ L  E AKL  E    ++   S S+   +  PS  S  
Sbjct: 521  DALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRA 580

Query: 188  LSPSASPTSSRSNSLTVPTP-PGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGEPNVPKG 246
              P A P    S ++  P P PG      PP P P  PP       +SSP    P++P G
Sbjct: 581  PVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP----PSLPGG 636

Query: 247  LADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGK 306
             A    +    +S     P PPP+ +   I         P   P  T     P    S +
Sbjct: 637  TAI---SPPPPLSGDATIPPPPPLPEGVGIP-------SPSSLPGGTAIPPPPPLPGSAR 686

Query: 307  MALNSPQPGPVESELG---KQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGP 363
            +    P P P+    G         G  G P P  P     G+ PP     GP   P  P
Sbjct: 687  IP---PPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP 743

Query: 364  EAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAK 423
              G    +PP    PP   G    + P  P     K L K  +      ++      L++
Sbjct: 744  GMG----MPPP---PPF--GFGVPAAPVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQ 794

Query: 424  APGLKDFQIQVQPVRMQKLTKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELSPAI 483
                  F  +V+  R +      +  +    Q        D  E  E++K +  +    +
Sbjct: 795  ----DCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKAKKD-QEGGEEKKSVQKKKVKEL 849

Query: 484  EEEESKSGLDVMPNISDVLLRKLRVHR-SLPGSAPPLTEKEVENVFVQL-------SLAF 535
            +  +SK+  ++   +    +    +    L  +   LTE  ++N+  Q+        L+ 
Sbjct: 850  KVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSE 909

Query: 536  RNDSY-----------------TLESRINQAERERNLTEENTEKELENFKASITSSASLW 578
              D Y                  L  R+N       L +    +++EN K  I S  +  
Sbjct: 910  LKDEYDDLAESEQFGVVMGTVPRLRPRLNAI-----LFKLQFSEQVENIKPEIVSVTAAC 964

Query: 579  HHCEHRETYQKLLEDIAVLHRLAARLSSRAEVVG---AVRQEKRMSKATEVMMQYVENLK 635
                  E++  LLE   ++       S  A   G   +   + R +K+T+  M  +  L 
Sbjct: 965  EELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLA 1024

Query: 636  RTYEKDHAELMEF-KKLANQNSSRSCGPSEDGVPRTARSMSLTLGKNMPRRRVSVAVVPK 694
               E D+ ++++F  +LA+             V + +R  +  L KN+ + +  ++ V +
Sbjct: 1025 ELCENDYPDVLKFPDELAH-------------VEKASRVSAENLQKNLDQMKKQISDVER 1071

Query: 695  FNALNLPGQT 704
             +  N P  T
Sbjct: 1072 -DVQNFPAAT 1080


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 71/256 (27%), Positives = 91/256 (35%), Gaps = 25/256 (9%)

Query: 186 PNLSPSASPTSSRSNSLTVP---TPPGLDVC--SGPPSPLPGAPPQKGDEADVSSPHPGE 240
           P+L+P   P  + S  LT P   TPP    C    PPSPL   PP+    + +++P    
Sbjct: 539 PSLAPP--PLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET--PSSIATP---P 591

Query: 241 PNVPKGLADRKQNDQRKVSQGRLA---PRPPPVEKSKEIAIEQKENFDPLQYPETTPKGL 297
           P  P  LA              LA   P+ PP      +         P   P  TP   
Sbjct: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ 651

Query: 298 APVTNSSGKMALNSP-QPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQ--GR 354
           AP  N+     L +P  P P                SP    P+Q    +  P  Q    
Sbjct: 652 AP--NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 709

Query: 355 GPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGP-----EEPGPRLQKVLAKLPLAEE 409
            PA  PM P A    + PP ++ PPL    S  + P       P PR+  +LA  PL   
Sbjct: 710 PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVP 769

Query: 410 EKRFAGKAGGKLAKAP 425
               A      LAK P
Sbjct: 770 PSPPASLPMSPLAKPP 785



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 57/226 (25%), Positives = 79/226 (34%), Gaps = 20/226 (8%)

Query: 181 PSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGE 240
           P A  P   P + P S   +    P P    + + PP  +P +PP     + ++ P    
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP---P 785

Query: 241 PNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGL--- 297
           P  P  LA      Q   S     P   P   S  + +       P Q P      L   
Sbjct: 786 PQAPPALATPPL--QALPSPPASFPGQAPFSPSASLPMSPLAT-PPPQAPPVLAAPLLQV 842

Query: 298 --APVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLP--RSPTQDAAG---VGPPA 350
             +P  + + +     P PGP  S  G +L      G P P  RSP+   +G    G  +
Sbjct: 843 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902

Query: 351 SQGRGP---AGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEP 393
           S    P    G   GPE G+ A  PP  +        +W  GP  P
Sbjct: 903 SATSTPEELRGYDSGPEGGAAAS-PPPDAELAACHPAAWSRGPAPP 947



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 58/225 (25%), Positives = 79/225 (35%), Gaps = 38/225 (16%)

Query: 176 SPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSS 235
           SP  SP   +P  SP ASP  S S +     PP L   + PP  +P +PP     +  ++
Sbjct: 666 SPPPSPPVQAP-FSPPASPPVSPSATPPSQAPPSL---AAPPLQVPPSPPASPPMSPSAT 721

Query: 236 PHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPK 295
           P P  P  P   A   Q          + P PP                 P   P  TP 
Sbjct: 722 PPPQAP--PPLAAPPLQ----------VPPSPPA---------------SPPMSPSATPP 754

Query: 296 GLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRG 355
              P   ++  + +    P P  S     L K   +  P   +P   A    P +  G+ 
Sbjct: 755 PRVPPLLAAPPLQV---PPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQA 811

Query: 356 P----AGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPR 396
           P    A  PM P A    + PP ++ P L    S  + P    PR
Sbjct: 812 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 856



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 71/260 (27%), Positives = 92/260 (35%), Gaps = 64/260 (24%)

Query: 175 SSPGDSPSAVSPNL--------------SPSASPTSSRSNSLTVPTPPGLDVCSGPPSPL 220
           +SP  SPSA  P+               SP ASP  S S +     PP L   + PP  +
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL---AAPPLQV 737

Query: 221 PGAPPQKGDEADVSSPHPGEPNVPKGLA----DRKQNDQRKVSQGRLAPRPPPVEKSKEI 276
           P +PP     +  ++P    P VP  LA        +    +    LA  PP    +   
Sbjct: 738 PPSPPASPPMSPSATP---PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT 794

Query: 277 AIEQKENFDPLQYPETTPKGLAPVTNSS----GKMALNSPQPGPVESELGKQLLKTGWEG 332
              Q     P  +P     G AP + S+      +A   PQ  PV   L   LL+     
Sbjct: 795 PPLQALPSPPASFP-----GQAPFSPSASLPMSPLATPPPQAPPV---LAAPLLQV--PP 844

Query: 333 SPLPRSPTQD---------------------AAGVGPPASQGRGPAGEPMGPEAGSKAEL 371
           SP P SPT                       A   GPP    R P+    GP+    +  
Sbjct: 845 SP-PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS- 902

Query: 372 PPTVSRPPLLRGLSWDSGPE 391
               S P  LRG  +DSGPE
Sbjct: 903 -SATSTPEELRG--YDSGPE 919



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 57/213 (26%), Positives = 82/213 (38%), Gaps = 32/213 (15%)

Query: 175 SSPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVS 234
           ++P   P + SP  +PS S T +R      P PP  +  +  P+ LP +PP     A   
Sbjct: 292 AAPALGPLSSSPLATPSPSGTKAR------PVPPPDNAATPLPATLPPSPPL----ATPL 341

Query: 235 SPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPE--T 292
              P  P+ P  L           SQ   +   PP++    +     +   P+Q P   T
Sbjct: 342 PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSL-----QTIPPIQVPHSLT 396

Query: 293 TPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQ 352
           +P   AP       +AL+S Q     + LG   L+     S L  SP Q  A +  P+  
Sbjct: 397 SPSLQAP----PSPLALSSLQ---ATTSLGSPTLQA--THSFLTMSPRQTQASLTSPSRP 447

Query: 353 GRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLS 385
              P   P  P   +   LP   + PPL   LS
Sbjct: 448 ASTP---PDSPPLQAPLSLP---ASPPLQTSLS 474



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 59/234 (25%), Positives = 80/234 (34%), Gaps = 30/234 (12%)

Query: 180 SPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADV------ 233
           SP    P  +PS+  T        + +PP   + S P SPL   PPQ      +      
Sbjct: 574 SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAP 633

Query: 234 SSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETT 293
            SP    P  P      +  +   V   +    PPP   S  +         P   P  T
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP---SPPVQAPFSPPASPPVSPSAT 690

Query: 294 PKGLAPVTNSSGKMAL-NSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPAS- 351
           P   AP + ++  + +  SP   P  S             +P P++P   AA   PP   
Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPASPPMSP----------SATPPPQAPPPLAA---PPLQV 737

Query: 352 QGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLAKLP 405
               PA  PM P A     +PP ++ PPL         P  P       LAK P
Sbjct: 738 PPSPPASPPMSPSATPPPRVPPLLAAPPL------QVPPSPPASLPMSPLAKPP 785



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 60/277 (21%), Positives = 85/277 (30%), Gaps = 56/277 (20%)

Query: 167 TRRGRKSRSSPGDSPSAV--------SPNLSPSASPTSSRSNSLTVPTPPGLD------- 211
           TR    S  +P   P A         + N SP    +  R++  T P P G         
Sbjct: 80  TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139

Query: 212 --VCSGPPSPLPGAPP-QKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPP 268
             V  G  +  P       G   D S P PG P+    +A R +    +V      PRP 
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPS--PAMARRSRAAGTEVG----LPRPA 193

Query: 269 PVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKT 328
           P  +                 P    +G     +S+ + +   P P        ++    
Sbjct: 194 PSAR-----------------PRPPTEGPRKSVSSASEHSTTEPSPA-----ARRRPSAG 231

Query: 329 GWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDS 388
           G    P  RS +  A  +  PA  G    G P  P   S+          P  +GL    
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ----------PKPKGLQALR 281

Query: 389 GPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKAP 425
            P+   PR     A  PL+         +G K    P
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVP 318


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 74/276 (26%), Positives = 95/276 (34%), Gaps = 49/276 (17%)

Query: 169  RGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNS------LTVPTPPGLDVCSGPPSP--- 219
            +G K    P   P  + P   P A+       +             G    +GPP P   
Sbjct: 1012 KGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGL 1071

Query: 220  --LPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIA 277
              LPG   +KG+  DV    P  P  P+G A     D  +   G +    PP EK     
Sbjct: 1072 QGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKG---- 1127

Query: 278  IEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPR 337
             E  E+  P    E   KG        G+    S QPG                G P P+
Sbjct: 1128 -EPGESGSPGIQGEPGVKGPRGERGEKGE----SGQPGE--------------PGPPGPK 1168

Query: 338  SPTQDAAGVGPPASQG----RGPAGE--PMGPEAGSKAELPPTVSRPPLLRGLSWDSGPE 391
             PT D    G P   G     GP GE  P G +              P   G + ++GP 
Sbjct: 1169 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGP- 1227

Query: 392  EPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKA-PG 426
             PGP  ++  A  P +E      G+ GGK AK  PG
Sbjct: 1228 -PGPLGKRGPAGSPGSE------GRQGGKGAKGDPG 1256



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 54/204 (26%), Positives = 73/204 (35%), Gaps = 49/204 (24%)

Query: 202 LTVPTPPGLDVCSGPPSPL--PGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVS 259
           L +  PPG    +G P PL  PG+P  KG+  D+    P  P  P+GL        R+  
Sbjct: 397 LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLG---PQGPRGPQGLTGPPGKAGRRGR 453

Query: 260 QGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVES 319
            G    R  P +      ++    FD          GL  +    G              
Sbjct: 454 AGADGARGMPGDPG----VKGDRGFD----------GLPGLPGEKGH-----------RG 488

Query: 320 ELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGR-GPAGEPMGPEAGSKAELPPTVSRP 378
           + G Q    G  G P       D   +GP    G  GP G  +GP+       PP +  P
Sbjct: 489 DTGAQ----GLPGPPGEDGERGDDGEIGPRGLPGESGPRGL-LGPKG------PPGIPGP 537

Query: 379 PLLRGLSWDSGPE-------EPGP 395
           P +RG+    GP+       EPGP
Sbjct: 538 PGVRGMDGPQGPKGSLGPQGEPGP 561



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 64/228 (28%), Positives = 82/228 (35%), Gaps = 57/228 (25%)

Query: 207  PPGLDVCSGPPSPLP--GAPPQKGDEADVSSPH-PGEPNV--PKGLADRKQNDQRKVSQG 261
            P G D   GPP  +   G P +KG+  +  SP   GEP V  P+G    K    +    G
Sbjct: 1104 PNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG 1163

Query: 262  RLAPRPPPVEKSKEIAIEQKENFDPLQYP-------ETTPKGLAPVTN------------ 302
               P+ P  +         K N  P+ +P       E  P+G                  
Sbjct: 1164 PPGPKGPTGDDGP------KGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1217

Query: 303  SSGKMALNSPQPGPVESELGKQ--LLKTGWEGSPLPRSPTQDAAGVGPPASQG----RGP 356
            S G    N P PGP    LGK+      G EG    +    D   +G P   G     GP
Sbjct: 1218 SPGPTGENGP-PGP----LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGP 1272

Query: 357  AGEPMGPEA-----GSKAEL----------PPTVSRPPLLRGLSWDSG 389
            AG+P GP+      GS  +           PP    PP L GL  D+G
Sbjct: 1273 AGKP-GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAG 1319



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 51/198 (25%), Positives = 71/198 (35%), Gaps = 28/198 (14%)

Query: 207 PPGLDVCSGPPSP-----LPGAPPQKGDEA-DVSSPHPGEPNV--PKGLADRKQNDQRKV 258
           P G     GPP P     LPG P Q+G+      +  PG P V  P+G A        + 
Sbjct: 798 PNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERG 857

Query: 259 SQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVE 318
             G   P PP  +     A ++    DP         G A +    G+  L     GP  
Sbjct: 858 HPG--PPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGP-- 913

Query: 319 SELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRP 378
                     G +G+  P  P   A   G P  +G   +G P+GP      + PP  +  
Sbjct: 914 ----------GLKGNEGPSGPPGPA---GSPGERGAAGSGGPIGPPGRPGPQGPPGAAGE 960

Query: 379 PLLRGLSWDSGPEEPGPR 396
              +G+  + GP  P  R
Sbjct: 961 ---KGVPGEKGPIGPTGR 975



 Score = 34.3 bits (77), Expect = 0.54
 Identities = 65/253 (25%), Positives = 82/253 (32%), Gaps = 57/253 (22%)

Query: 153 ALLEEAKLVSERFLTRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDV 212
           A+L++A+L         G   R  P   P   SP L          S  L    P G   
Sbjct: 390 AILQQARLALRGPPGPMGYTGRPGPLGQPG--SPGLK-------GESGDLGPQGPRGPQG 440

Query: 213 CSGPPSP--------------LPGAPPQKGDEADVSSPH-PGEPNV-----PKGLADRKQ 252
            +GPP                +PG P  KGD      P  PGE         +GL     
Sbjct: 441 LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 500

Query: 253 NDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSP 312
            D  +   G + PR  P E      +  K    P   P   P G+  +    G      P
Sbjct: 501 EDGERGDDGEIGPRGLPGESGPRGLLGPK---GPPGIPG--PPGVRGMDGPQGPKGSLGP 555

Query: 313 Q--PGPV--ESELGKQLL-----------------KTGWEGSPLPRSPTQDAAGVGPPAS 351
           Q  PGP   +   G Q L                 K G  G P    P       GPP +
Sbjct: 556 QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT 615

Query: 352 QG-RGPAGEPMGP 363
           +G +GP+G P GP
Sbjct: 616 KGNQGPSG-PQGP 627


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 74/276 (26%), Positives = 95/276 (34%), Gaps = 49/276 (17%)

Query: 169  RGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNS------LTVPTPPGLDVCSGPPSP--- 219
            +G K    P   P  + P   P A+       +             G    +GPP P   
Sbjct: 991  KGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGL 1050

Query: 220  --LPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIA 277
              LPG   +KG+  DV    P  P  P+G A     D  +   G +    PP EK     
Sbjct: 1051 QGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKG---- 1106

Query: 278  IEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPR 337
             E  E+  P    E   KG        G+    S QPG                G P P+
Sbjct: 1107 -EPGESGSPGIQGEPGVKGPRGERGEKGE----SGQPGE--------------PGPPGPK 1147

Query: 338  SPTQDAAGVGPPASQG----RGPAGE--PMGPEAGSKAELPPTVSRPPLLRGLSWDSGPE 391
             PT D    G P   G     GP GE  P G +              P   G + ++GP 
Sbjct: 1148 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGP- 1206

Query: 392  EPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKA-PG 426
             PGP  ++  A  P +E      G+ GGK AK  PG
Sbjct: 1207 -PGPLGKRGPAGSPGSE------GRQGGKGAKGDPG 1235



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 54/204 (26%), Positives = 73/204 (35%), Gaps = 49/204 (24%)

Query: 202 LTVPTPPGLDVCSGPPSPL--PGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVS 259
           L +  PPG    +G P PL  PG+P  KG+  D+    P  P  P+GL        R+  
Sbjct: 376 LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLG---PQGPRGPQGLTGPPGKAGRRGR 432

Query: 260 QGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVES 319
            G    R  P +      ++    FD          GL  +    G              
Sbjct: 433 AGADGARGMPGDPG----VKGDRGFD----------GLPGLPGEKGH-----------RG 467

Query: 320 ELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGR-GPAGEPMGPEAGSKAELPPTVSRP 378
           + G Q    G  G P       D   +GP    G  GP G  +GP+       PP +  P
Sbjct: 468 DTGAQ----GLPGPPGEDGERGDDGEIGPRGLPGESGPRGL-LGPKG------PPGIPGP 516

Query: 379 PLLRGLSWDSGPE-------EPGP 395
           P +RG+    GP+       EPGP
Sbjct: 517 PGVRGMDGPQGPKGSLGPQGEPGP 540



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 64/228 (28%), Positives = 82/228 (35%), Gaps = 57/228 (25%)

Query: 207  PPGLDVCSGPPSPLP--GAPPQKGDEADVSSPH-PGEPNV--PKGLADRKQNDQRKVSQG 261
            P G D   GPP  +   G P +KG+  +  SP   GEP V  P+G    K    +    G
Sbjct: 1083 PNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG 1142

Query: 262  RLAPRPPPVEKSKEIAIEQKENFDPLQYP-------ETTPKGLAPVTN------------ 302
               P+ P  +         K N  P+ +P       E  P+G                  
Sbjct: 1143 PPGPKGPTGDDGP------KGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1196

Query: 303  SSGKMALNSPQPGPVESELGKQ--LLKTGWEGSPLPRSPTQDAAGVGPPASQG----RGP 356
            S G    N P PGP    LGK+      G EG    +    D   +G P   G     GP
Sbjct: 1197 SPGPTGENGP-PGP----LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGP 1251

Query: 357  AGEPMGPEA-----GSKAEL----------PPTVSRPPLLRGLSWDSG 389
            AG+P GP+      GS  +           PP    PP L GL  D+G
Sbjct: 1252 AGKP-GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAG 1298



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 51/198 (25%), Positives = 71/198 (35%), Gaps = 28/198 (14%)

Query: 207 PPGLDVCSGPPSP-----LPGAPPQKGDEA-DVSSPHPGEPNV--PKGLADRKQNDQRKV 258
           P G     GPP P     LPG P Q+G+      +  PG P V  P+G A        + 
Sbjct: 777 PNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERG 836

Query: 259 SQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVE 318
             G   P PP  +     A ++    DP         G A +    G+  L     GP  
Sbjct: 837 HPG--PPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGP-- 892

Query: 319 SELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRP 378
                     G +G+  P  P   A   G P  +G   +G P+GP      + PP  +  
Sbjct: 893 ----------GLKGNEGPSGPPGPA---GSPGERGAAGSGGPIGPPGRPGPQGPPGAAGE 939

Query: 379 PLLRGLSWDSGPEEPGPR 396
              +G+  + GP  P  R
Sbjct: 940 ---KGVPGEKGPIGPTGR 954



 Score = 34.3 bits (77), Expect = 0.54
 Identities = 65/253 (25%), Positives = 82/253 (32%), Gaps = 57/253 (22%)

Query: 153 ALLEEAKLVSERFLTRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDV 212
           A+L++A+L         G   R  P   P   SP L          S  L    P G   
Sbjct: 369 AILQQARLALRGPPGPMGYTGRPGPLGQPG--SPGLK-------GESGDLGPQGPRGPQG 419

Query: 213 CSGPPSP--------------LPGAPPQKGDEADVSSPH-PGEPNV-----PKGLADRKQ 252
            +GPP                +PG P  KGD      P  PGE         +GL     
Sbjct: 420 LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 479

Query: 253 NDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSP 312
            D  +   G + PR  P E      +  K    P   P   P G+  +    G      P
Sbjct: 480 EDGERGDDGEIGPRGLPGESGPRGLLGPK---GPPGIPG--PPGVRGMDGPQGPKGSLGP 534

Query: 313 Q--PGPV--ESELGKQLL-----------------KTGWEGSPLPRSPTQDAAGVGPPAS 351
           Q  PGP   +   G Q L                 K G  G P    P       GPP +
Sbjct: 535 QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT 594

Query: 352 QG-RGPAGEPMGP 363
           +G +GP+G P GP
Sbjct: 595 KGNQGPSG-PQGP 606


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 74/276 (26%), Positives = 95/276 (34%), Gaps = 49/276 (17%)

Query: 169  RGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNS------LTVPTPPGLDVCSGPPSP--- 219
            +G K    P   P  + P   P A+       +             G    +GPP P   
Sbjct: 1098 KGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGL 1157

Query: 220  --LPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIA 277
              LPG   +KG+  DV    P  P  P+G A     D  +   G +    PP EK     
Sbjct: 1158 QGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKG---- 1213

Query: 278  IEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPR 337
             E  E+  P    E   KG        G+    S QPG                G P P+
Sbjct: 1214 -EPGESGSPGIQGEPGVKGPRGERGEKGE----SGQPGE--------------PGPPGPK 1254

Query: 338  SPTQDAAGVGPPASQG----RGPAGE--PMGPEAGSKAELPPTVSRPPLLRGLSWDSGPE 391
             PT D    G P   G     GP GE  P G +              P   G + ++GP 
Sbjct: 1255 GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGP- 1313

Query: 392  EPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKA-PG 426
             PGP  ++  A  P +E      G+ GGK AK  PG
Sbjct: 1314 -PGPLGKRGPAGSPGSE------GRQGGKGAKGDPG 1342



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 54/204 (26%), Positives = 73/204 (35%), Gaps = 49/204 (24%)

Query: 202 LTVPTPPGLDVCSGPPSPL--PGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVS 259
           L +  PPG    +G P PL  PG+P  KG+  D+    P  P  P+GL        R+  
Sbjct: 483 LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLG---PQGPRGPQGLTGPPGKAGRRGR 539

Query: 260 QGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVES 319
            G    R  P +      ++    FD          GL  +    G              
Sbjct: 540 AGADGARGMPGDPG----VKGDRGFD----------GLPGLPGEKGH-----------RG 574

Query: 320 ELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGR-GPAGEPMGPEAGSKAELPPTVSRP 378
           + G Q    G  G P       D   +GP    G  GP G  +GP+       PP +  P
Sbjct: 575 DTGAQ----GLPGPPGEDGERGDDGEIGPRGLPGESGPRGL-LGPKG------PPGIPGP 623

Query: 379 PLLRGLSWDSGPE-------EPGP 395
           P +RG+    GP+       EPGP
Sbjct: 624 PGVRGMDGPQGPKGSLGPQGEPGP 647



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 64/228 (28%), Positives = 82/228 (35%), Gaps = 57/228 (25%)

Query: 207  PPGLDVCSGPPSPLP--GAPPQKGDEADVSSPH-PGEPNV--PKGLADRKQNDQRKVSQG 261
            P G D   GPP  +   G P +KG+  +  SP   GEP V  P+G    K    +    G
Sbjct: 1190 PNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG 1249

Query: 262  RLAPRPPPVEKSKEIAIEQKENFDPLQYP-------ETTPKGLAPVTN------------ 302
               P+ P  +         K N  P+ +P       E  P+G                  
Sbjct: 1250 PPGPKGPTGDDGP------KGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1303

Query: 303  SSGKMALNSPQPGPVESELGKQ--LLKTGWEGSPLPRSPTQDAAGVGPPASQG----RGP 356
            S G    N P PGP    LGK+      G EG    +    D   +G P   G     GP
Sbjct: 1304 SPGPTGENGP-PGP----LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGP 1358

Query: 357  AGEPMGPEA-----GSKAEL----------PPTVSRPPLLRGLSWDSG 389
            AG+P GP+      GS  +           PP    PP L GL  D+G
Sbjct: 1359 AGKP-GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAG 1405



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 51/198 (25%), Positives = 71/198 (35%), Gaps = 28/198 (14%)

Query: 207  PPGLDVCSGPPSP-----LPGAPPQKGDEA-DVSSPHPGEPNV--PKGLADRKQNDQRKV 258
            P G     GPP P     LPG P Q+G+      +  PG P V  P+G A        + 
Sbjct: 884  PNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERG 943

Query: 259  SQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVE 318
              G   P PP  +     A ++    DP         G A +    G+  L     GP  
Sbjct: 944  HPG--PPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGP-- 999

Query: 319  SELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRP 378
                      G +G+  P  P   A   G P  +G   +G P+GP      + PP  +  
Sbjct: 1000 ----------GLKGNEGPSGPPGPA---GSPGERGAAGSGGPIGPPGRPGPQGPPGAAGE 1046

Query: 379  PLLRGLSWDSGPEEPGPR 396
               +G+  + GP  P  R
Sbjct: 1047 ---KGVPGEKGPIGPTGR 1061



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 96/398 (24%), Positives = 130/398 (32%), Gaps = 89/398 (22%)

Query: 11  VSPACGAQASWSIFGADAAEVPGTRGHSQQEAAMPHIPEDEEPPGEPQAAQSPAGQ-GPP 69
           + PA  A+ + S  GA A    G +G   + A +      E PPG     + PAG  GPP
Sbjct: 360 LGPALSAETAHS--GAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGP----EGPAGLIGPP 413

Query: 70  TAGVSCSPTPTIVLTGDA--TSPEGETDKNLANRVHSPHKRLSHRHLKVSTASLTSVDPA 127
             G+  +P P     GD     P G      ++    P         +  +         
Sbjct: 414 --GIQGNPGPV----GDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGG------- 460

Query: 128 GHIIDLVNDQLPDISISEEDKKKNLALLEEAKLVSERFLTRRGRKSRSSPGDSPSAVSPN 187
                   D+ P ++  E   +   A+L++A+L         G   R  P   P   SP 
Sbjct: 461 -------GDKGPVVAAQEAQAQ---AILQQARLALRGPPGPMGYTGRPGPLGQPG--SPG 508

Query: 188 LSPSASPTSSRSNSLTVPTPPGLDVCSGPPSP--------------LPGAPPQKGDEADV 233
           L          S  L    P G    +GPP                +PG P  KGD    
Sbjct: 509 LK-------GESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFD 561

Query: 234 SSPH-PGEPNV-----PKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPL 287
             P  PGE         +GL      D  +   G + PR  P E      +  K    P 
Sbjct: 562 GLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK---GPP 618

Query: 288 QYPETTPKGLAPVTNSSGKMALNSPQ--PGPV--ESELGKQLL----------------- 326
             P   P G+  +    G      PQ  PGP   +   G Q L                 
Sbjct: 619 GIPG--PPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG 676

Query: 327 KTGWEGSPLPRSPTQDAAGVGPPASQG-RGPAGEPMGP 363
           K G  G P    P       GPP ++G +GP+G P GP
Sbjct: 677 KPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG-PQGP 713


>gi|44662807 hypothetical protein LOC388407 [Homo sapiens]
          Length = 251

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 63/246 (25%), Positives = 85/246 (34%), Gaps = 41/246 (16%)

Query: 155 LEEAKLVSERFLTRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCS 214
           L    L  E    R G+  +SSP  SPS     L P    T  ++ S   P+ P    CS
Sbjct: 10  LRALDLYPEPAFLRSGKDPKSSPASSPSFAV--LGPEVRSTGGQAGSRRRPSAP----CS 63

Query: 215 GPPSPLPGAPPQKGDEADVSSPHPGEPNVPKGLAD------RKQNDQRKVSQGRLAPRPP 268
              +   GAP   G      SP  G P  P G A       R  N       G     P 
Sbjct: 64  QDRAAAEGAPALLG-----GSPSSGSPGHPPGSAFGVEAGCRALNVSEHARGGFALGLPF 118

Query: 269 PVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKT 328
            +     + +      DP   PE      AP++++ G+    S               ++
Sbjct: 119 GLSGGAYLFLLLDGAGDPKPTPE------APISSADGRAWFPS---------------ES 157

Query: 329 GWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDS 388
            W+   LP+ P    +G  P A  G GP   P GP  G+  + P       L R    D 
Sbjct: 158 SWQ---LPQLPAGSTSGSEPRARPGLGPRQLPTGPRDGAAGQGPGRGLTARLGREREIDC 214

Query: 389 GPEEPG 394
           GP + G
Sbjct: 215 GPRQAG 220


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 19/146 (13%)

Query: 702 GQTPSSSSIPSLPALSESPNGKGSLP------------VTSALPALLENGKTNGD--PDC 747
           G   +S  +P+     E P   G LP            VT   P L+  G   G   P  
Sbjct: 815 GPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPAL 874

Query: 748 EASAPALTLSCLEELSQETKARMEEEAYSKGFQEGLKKTKE-----LQDLKEEEEEQKSE 802
           E     + ++  +E  +E +   EEE   +  +E  ++ +E      ++ +EEEEE + E
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEE 934

Query: 803 SPEEPEEVEETEEEEKGPRSSKLEEL 828
             EE  E+EE EEEE      +LEE+
Sbjct: 935 FEEEEGELEEEEEEEDEEEEEELEEV 960



 Score = 37.7 bits (86), Expect = 0.049
 Identities = 24/57 (42%), Positives = 33/57 (57%), Gaps = 9/57 (15%)

Query: 771 EEEAYSKGFQEGLKKTKELQDLKEEEEEQKSESPEEPEEVEETEEEEKGPRSSKLEE 827
           EEE + + F+E      E  +L+EEEEE   E  EE EE+EE E+ E G    ++EE
Sbjct: 927 EEEEFEEEFEE------EEGELEEEEEE---EDEEEEEELEEVEDLEFGTAGGEVEE 974



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 18/49 (36%), Positives = 29/49 (59%)

Query: 783 LKKTKELQDLKEEEEEQKSESPEEPEEVEETEEEEKGPRSSKLEELVHF 831
           +  + E ++ +EEEEE++ E  EE E+ EE EE+E+     + EE   F
Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEF 931



 Score = 35.0 bits (79), Expect = 0.32
 Identities = 57/227 (25%), Positives = 71/227 (31%), Gaps = 43/227 (18%)

Query: 176 SPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSS 235
           +P   P A SP  +P   P          P P    + S  P P  G  P  G    V S
Sbjct: 649 APVPPPEAPSPFRAPPFHPPG--------PMPSVGSMPSAGPMPSAGPMPSAGP---VPS 697

Query: 236 PHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPK 295
             PG P     L          +S   L   PP +    E       N DP+  P  TP 
Sbjct: 698 ARPGPPTTANHLG---------LSVPGLVSVPPRLLPGPENH-RAGSNEDPILAPSGTPP 747

Query: 296 GLAPVTNSSGKMALNSPQPGPV--------------ESELGKQLLKTGWEGSPLPRSPTQ 341
              P   + G      P+P  V              ES+    ++       PLP  P  
Sbjct: 748 PTIPPDETFGGRV---PRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPS 804

Query: 342 DA-----AGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRG 383
            A     A  GPP +    PA E       +   LPP    PP + G
Sbjct: 805 GATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPG 851


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 53/202 (26%), Positives = 75/202 (37%), Gaps = 21/202 (10%)

Query: 180 SPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSP--LPGAPPQKGDEADVSSPH 237
           S   ++ ++S   SP+    N    P+P G +   GPP P   P  PP +G       P 
Sbjct: 15  SAQNLNEDVSQEESPSLIAGNPQG-PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP 73

Query: 238 PGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGL 297
           PG+P  P    D+ ++ +    +    P+ PP +  K           P       P+G 
Sbjct: 74  PGKPQGPPPQGDKSRSPRSPPGK----PQGPPPQGGKPQG--------PPPQGGNKPQGP 121

Query: 298 APVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPA 357
            P     G  A    +     S  GK       EG+  P+ P   A   G P      PA
Sbjct: 122 PPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNN-PQGPPPPAG--GNPQQPQAPPA 178

Query: 358 GEPMGPEAGSKAELPPTVSRPP 379
           G+P GP    +   P   SRPP
Sbjct: 179 GQPQGPPRPPQGGRP---SRPP 197



 Score = 35.0 bits (79), Expect = 0.32
 Identities = 29/119 (24%), Positives = 39/119 (32%), Gaps = 4/119 (3%)

Query: 178 GDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPH 237
           G+ P    P   P   P      S +  +PPG      P    P  PP +G       P 
Sbjct: 65  GNKPQGPPPPGKPQGPPPQG-DKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKPQGPPP 123

Query: 238 PGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKG 296
           PG+P  P      K    R    G+  P+ PP ++               Q P+  P G
Sbjct: 124 PGKPQGPPAQGGSKSQSARS-PPGK--PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAG 179



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 32/117 (27%), Positives = 38/117 (32%), Gaps = 19/117 (16%)

Query: 169 RGRKSRS--SPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSP------- 219
           +G KSRS  SP   P    P       P     N    P PPG     GPP+        
Sbjct: 83  QGDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKPQGPPPPGKP--QGPPAQGGSKSQS 140

Query: 220 ------LPGAPPQKGDEADVSSPHP--GEPNVPKGLADRKQNDQRKVSQGRLAPRPP 268
                  P  PPQ+        P P  G P  P+     +     +  QG    RPP
Sbjct: 141 ARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 197



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 54/219 (24%), Positives = 73/219 (33%), Gaps = 60/219 (27%)

Query: 217 PSPLPGAP----PQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEK 272
           PS + G P    PQ G++     P PG+P  P               QG   P+ PP   
Sbjct: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPP-------------PQGGNKPQGPP--- 72

Query: 273 SKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEG 332
                            P   P+G  P  + S      SP+  P     GK       +G
Sbjct: 73  -----------------PPGKPQGPPPQGDKS-----RSPRSPP-----GKP------QG 99

Query: 333 SPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEA--GSKAEL----PPTVSRPPLLRGLSW 386
            P      Q     G    QG  P G+P GP A  GSK++     P     PP   G + 
Sbjct: 100 PPPQGGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNP 159

Query: 387 DSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKAP 425
              P   G   Q+  A  P  + +       GG+ ++ P
Sbjct: 160 QGPPPPAGGNPQQPQAP-PAGQPQGPPRPPQGGRPSRPP 197


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 58/195 (29%), Positives = 75/195 (38%), Gaps = 12/195 (6%)

Query: 208  PGLDVCSGPPSPL--PGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAP 265
            PG     GPP P+  PG     G+     SP    P    G A  K +     + G  AP
Sbjct: 1010 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVG--AP 1067

Query: 266  RPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVES-ELGKQ 324
              P    S   A    +  D  +     P G +    + G      P+    E+ E G++
Sbjct: 1068 GAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGER 1127

Query: 325  LLK-----TGWEGSPLPRSPTQDAAGVGPPASQG-RGPAGEPMGPEAGSKAELPPTVSRP 378
             LK     TG +G P P  P+ D    GP    G RGP G P+GP     A   P    P
Sbjct: 1128 GLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPG-PVGPSGKDGANGIPGPIGP 1186

Query: 379  PLLRGLSWDSGPEEP 393
            P  RG S ++GP  P
Sbjct: 1187 PGPRGRSGETGPAGP 1201



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 61/238 (25%), Positives = 84/238 (35%), Gaps = 20/238 (8%)

Query: 168  RRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQK 227
            ++G    S     P  V P      +    R  S     PPG D  +G           +
Sbjct: 1006 KQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG-------DR 1058

Query: 228  GDEADVSSPH-PGEPNVPKGLADR-KQNDQRKV-SQGRLAPRPPPVEKSKEIAIEQKENF 284
            G+   V +P  PG P  P       KQ D+ +  +QG + P  P    ++ I   Q    
Sbjct: 1059 GETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPA--GARGIQGPQGPRG 1116

Query: 285  DPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESE-LGKQLLKTGWEGSPLPRSPT-QD 342
            D  +  E   +GL      +G   L  P PGP   +        +G  G P P  P+ +D
Sbjct: 1117 DKGEAGEPGERGLKGHRGFTGLQGLPGP-PGPSGDQGASGPAGPSGPRGPPGPVGPSGKD 1175

Query: 343  AAG-----VGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGP 395
             A      +GPP  +GR     P GP        PP    P +        GP E GP
Sbjct: 1176 GANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGP 1233



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 67/244 (27%), Positives = 84/244 (34%), Gaps = 36/244 (14%)

Query: 169  RGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSP--LPGA--- 223
            +G +  +       A  P   PS +P       +T   P G     GPP     PGA   
Sbjct: 848  KGEQGEAGQKGDAGAPGPQ-GPSGAPGPQGPTGVT--GPKGARGAQGPPGATGFPGAAGR 904

Query: 224  ---PPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQ 280
               P   G+      P P   + PKG         R    G   P  PP EK      E 
Sbjct: 905  VGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG-----EP 959

Query: 281  KENFDPLQYPETTPKGLAPVTNSSGKMALNSPQ-----PGPVESELGKQLLKTGWEGSPL 335
             ++          P+GLA      G       +     PGP   E GKQ    G  G+  
Sbjct: 960  GDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGP-SGEPGKQ----GAPGASG 1014

Query: 336  PRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSG----PE 391
             R P      VGPP     GPAGEP G E    A+ PP       ++G   ++G    P 
Sbjct: 1015 DRGP---PGPVGPPGL--TGPAGEP-GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPG 1068

Query: 392  EPGP 395
             PGP
Sbjct: 1069 APGP 1072



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 65/259 (25%), Positives = 87/259 (33%), Gaps = 52/259 (20%)

Query: 177 PGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPL-----PGAPPQKGDEA 231
           PG   SA +P ++ +      R        PPG    +GP  P      PG    KG++ 
Sbjct: 416 PGAKGSAGAPGIAGAPGFPGPRG-------PPGPQGATGPLGPKGQTGEPGIAGFKGEQG 468

Query: 232 DVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPE 291
               P P  P    G A  +     +   G + P  PP E                    
Sbjct: 469 PKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGE-------------------- 508

Query: 292 TTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPAS 351
              +G        G+  L  P+  P E          G  G   P+    D    G P  
Sbjct: 509 ---RGAPGNRGFPGQDGLAGPKGAPGE---------RGPSGLAGPKGANGDPGRPGEPGL 556

Query: 352 QG-RGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLAKLPLAEEE 410
            G RG  G P   +AG + ++ P  S  P   G     GP+  G R Q  +   P  +  
Sbjct: 557 PGARGLTGRP--GDAGPQGKVGP--SGAPGEDGRPGPPGPQ--GARGQPGVMGFPGPKGA 610

Query: 411 KRFAGKAGGK-LAKAPGLK 428
               GKAG K L  APGL+
Sbjct: 611 NGEPGKAGEKGLPGAPGLR 629



 Score = 38.1 bits (87), Expect = 0.037
 Identities = 64/249 (25%), Positives = 82/249 (32%), Gaps = 37/249 (14%)

Query: 174 RSSPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADV 233
           R  PG      +      A P   R      P P G     GPP P PG   + GD+   
Sbjct: 629 RGLPGKDGETGAAGPPGPAGPAGERGEQ-GAPGPSGFQGLPGPPGP-PGEGGKPGDQGV- 685

Query: 234 SSPHPGEPNVPKGLADRKQND-----QRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQ 288
               PGE   P  +  R +           +QG   PR  P     +     K    P  
Sbjct: 686 ----PGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD---GPKGASGPAG 738

Query: 289 YPETT-PKGLAPVTNSSGKMALNSP--------QPGPVESELGKQLLK--TGWEGSPLPR 337
            P    P GL  +    G   +  P        + GP E   GK   +  TG  G P P 
Sbjct: 739 PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGP-EGAPGKDGGRGLTGPIGPPGPA 797

Query: 338 SPTQDAAGVGPPASQG----RGPAGE--PMGPEAGSKAELPPTVSRPPLLRGLSWDSGPE 391
               +   VGPP   G    RG  GE    GP   +    PP     P  +G   ++G +
Sbjct: 798 GANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQK 857

Query: 392 ----EPGPR 396
                PGP+
Sbjct: 858 GDAGAPGPQ 866



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 50/224 (22%), Positives = 65/224 (29%), Gaps = 77/224 (34%)

Query: 205 PTPPGLDVCSGPPSPLPGAPPQKGDEADVSSP----------------HPGEPNVP---- 244
           P  PG+    GP  P PG P + GD+ +   P                 PG P +P    
Sbjct: 230 PGEPGVSGPMGPRGP-PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKG 288

Query: 245 ----------------KGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQ 288
                            G+     +     S G + PR  P E+ +              
Sbjct: 289 HRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR-------------- 334

Query: 289 YPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGP 348
              T P G A    + G       QPGP               G P P  P       G 
Sbjct: 335 ---TGPAGAAGARGNDG-------QPGPA--------------GPPGPVGPAGGPGFPGA 370

Query: 349 PASQGR-GPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPE 391
           P ++G  GP G   GPE        P     P   G S + G +
Sbjct: 371 PGAKGEAGPTG-ARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 413


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 58/195 (29%), Positives = 75/195 (38%), Gaps = 12/195 (6%)

Query: 208  PGLDVCSGPPSPL--PGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAP 265
            PG     GPP P+  PG     G+     SP    P    G A  K +     + G  AP
Sbjct: 941  PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVG--AP 998

Query: 266  RPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVES-ELGKQ 324
              P    S   A    +  D  +     P G +    + G      P+    E+ E G++
Sbjct: 999  GAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGER 1058

Query: 325  LLK-----TGWEGSPLPRSPTQDAAGVGPPASQG-RGPAGEPMGPEAGSKAELPPTVSRP 378
             LK     TG +G P P  P+ D    GP    G RGP G P+GP     A   P    P
Sbjct: 1059 GLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPG-PVGPSGKDGANGIPGPIGP 1117

Query: 379  PLLRGLSWDSGPEEP 393
            P  RG S ++GP  P
Sbjct: 1118 PGPRGRSGETGPAGP 1132



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 61/238 (25%), Positives = 84/238 (35%), Gaps = 20/238 (8%)

Query: 168  RRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQK 227
            ++G    S     P  V P      +    R  S     PPG D  +G           +
Sbjct: 937  KQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG-------DR 989

Query: 228  GDEADVSSPH-PGEPNVPKGLADR-KQNDQRKV-SQGRLAPRPPPVEKSKEIAIEQKENF 284
            G+   V +P  PG P  P       KQ D+ +  +QG + P  P    ++ I   Q    
Sbjct: 990  GETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPA--GARGIQGPQGPRG 1047

Query: 285  DPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESE-LGKQLLKTGWEGSPLPRSPT-QD 342
            D  +  E   +GL      +G   L  P PGP   +        +G  G P P  P+ +D
Sbjct: 1048 DKGEAGEPGERGLKGHRGFTGLQGLPGP-PGPSGDQGASGPAGPSGPRGPPGPVGPSGKD 1106

Query: 343  AAG-----VGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGP 395
             A      +GPP  +GR     P GP        PP    P +        GP E GP
Sbjct: 1107 GANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGP 1164



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 67/244 (27%), Positives = 84/244 (34%), Gaps = 36/244 (14%)

Query: 169  RGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSP--LPGA--- 223
            +G +  +       A  P   PS +P       +T   P G     GPP     PGA   
Sbjct: 779  KGEQGEAGQKGDAGAPGPQ-GPSGAPGPQGPTGVT--GPKGARGAQGPPGATGFPGAAGR 835

Query: 224  ---PPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQ 280
               P   G+      P P   + PKG         R    G   P  PP EK      E 
Sbjct: 836  VGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG-----EP 890

Query: 281  KENFDPLQYPETTPKGLAPVTNSSGKMALNSPQ-----PGPVESELGKQLLKTGWEGSPL 335
             ++          P+GLA      G       +     PGP   E GKQ    G  G+  
Sbjct: 891  GDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGP-SGEPGKQ----GAPGASG 945

Query: 336  PRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSG----PE 391
             R P      VGPP     GPAGEP G E    A+ PP       ++G   ++G    P 
Sbjct: 946  DRGP---PGPVGPPGL--TGPAGEP-GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPG 999

Query: 392  EPGP 395
             PGP
Sbjct: 1000 APGP 1003



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 65/259 (25%), Positives = 87/259 (33%), Gaps = 52/259 (20%)

Query: 177 PGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPL-----PGAPPQKGDEA 231
           PG   SA +P ++ +      R        PPG    +GP  P      PG    KG++ 
Sbjct: 347 PGAKGSAGAPGIAGAPGFPGPRG-------PPGPQGATGPLGPKGQTGEPGIAGFKGEQG 399

Query: 232 DVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPE 291
               P P  P    G A  +     +   G + P  PP E                    
Sbjct: 400 PKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGE-------------------- 439

Query: 292 TTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPAS 351
              +G        G+  L  P+  P E          G  G   P+    D    G P  
Sbjct: 440 ---RGAPGNRGFPGQDGLAGPKGAPGE---------RGPSGLAGPKGANGDPGRPGEPGL 487

Query: 352 QG-RGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLAKLPLAEEE 410
            G RG  G P   +AG + ++ P  S  P   G     GP+  G R Q  +   P  +  
Sbjct: 488 PGARGLTGRP--GDAGPQGKVGP--SGAPGEDGRPGPPGPQ--GARGQPGVMGFPGPKGA 541

Query: 411 KRFAGKAGGK-LAKAPGLK 428
               GKAG K L  APGL+
Sbjct: 542 NGEPGKAGEKGLPGAPGLR 560



 Score = 38.1 bits (87), Expect = 0.037
 Identities = 64/249 (25%), Positives = 82/249 (32%), Gaps = 37/249 (14%)

Query: 174 RSSPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADV 233
           R  PG      +      A P   R      P P G     GPP P PG   + GD+   
Sbjct: 560 RGLPGKDGETGAAGPPGPAGPAGERGEQ-GAPGPSGFQGLPGPPGP-PGEGGKPGDQGV- 616

Query: 234 SSPHPGEPNVPKGLADRKQND-----QRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQ 288
               PGE   P  +  R +           +QG   PR  P     +     K    P  
Sbjct: 617 ----PGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD---GPKGASGPAG 669

Query: 289 YPETT-PKGLAPVTNSSGKMALNSP--------QPGPVESELGKQLLK--TGWEGSPLPR 337
            P    P GL  +    G   +  P        + GP E   GK   +  TG  G P P 
Sbjct: 670 PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGP-EGAPGKDGGRGLTGPIGPPGPA 728

Query: 338 SPTQDAAGVGPPASQG----RGPAGE--PMGPEAGSKAELPPTVSRPPLLRGLSWDSGPE 391
               +   VGPP   G    RG  GE    GP   +    PP     P  +G   ++G +
Sbjct: 729 GANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQK 788

Query: 392 ----EPGPR 396
                PGP+
Sbjct: 789 GDAGAPGPQ 797



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 63/227 (27%), Positives = 82/227 (36%), Gaps = 21/227 (9%)

Query: 213 CSGPPSPLPGAPPQKGDEADVSS-PHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVE 271
           C G     PG   QKG+  D+     P  P  P+G A  +     +  +G    +  P  
Sbjct: 23  CQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQ---GPRGDRGDKGEKGAPGP 79

Query: 272 KSKEIAIEQKENFDPLQYP-ETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQL-LKTG 329
           + ++       N  P   P    P GL    N + +MA      G  E   G QL +  G
Sbjct: 80  RGRDGEPGTPGNPGPPGPPGPPGPPGLG--GNFAAQMA-----GGFDEKAGGAQLGVMQG 132

Query: 330 WEGSPLPRSPTQDAAGVGPPASQGR-GPAGE-----PMGPEAGSKAELPPTVSRPPLLRG 383
             G   PR P   A   GP   QG  G  GE     PMGP         P         G
Sbjct: 133 PMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPG 192

Query: 384 LSWDSGPEEP-GPRLQKVLAKLPLAEEEKRFAGKAGGK-LAKAPGLK 428
            + + GP  P G R       LP  +  + + G  G K  A APG+K
Sbjct: 193 KAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVK 239



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 50/224 (22%), Positives = 65/224 (29%), Gaps = 77/224 (34%)

Query: 205 PTPPGLDVCSGPPSPLPGAPPQKGDEADVSSP----------------HPGEPNVP---- 244
           P  PG+    GP  P PG P + GD+ +   P                 PG P +P    
Sbjct: 161 PGEPGVSGPMGPRGP-PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKG 219

Query: 245 ----------------KGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQ 288
                            G+     +     S G + PR  P E+ +              
Sbjct: 220 HRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR-------------- 265

Query: 289 YPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGP 348
              T P G A    + G       QPGP               G P P  P       G 
Sbjct: 266 ---TGPAGAAGARGNDG-------QPGPA--------------GPPGPVGPAGGPGFPGA 301

Query: 349 PASQGR-GPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPE 391
           P ++G  GP G   GPE        P     P   G S + G +
Sbjct: 302 PGAKGEAGPTG-ARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 344


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 87/356 (24%), Positives = 123/356 (34%), Gaps = 61/356 (17%)

Query: 53  PPGEPQAAQSPAGQGPPTAGVSCSP-TPTIVLTGDATSPEGETDKNLANRVHSPHKRLSH 111
           P G P  A SP G  PP A +S  P T  ++ T    SP G   +    ++ S    ++ 
Sbjct: 220 PTGTPPRA-SPTGS-PPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTAS-ITR 276

Query: 112 RHLKVSTASLTSVDPAGHIIDLVND------QLPDISISEEDKKKNLALLEEAKLVSER- 164
              + STAS T   P+   + +          LP  S +    + +L  ++    +S   
Sbjct: 277 TPSRPSTASPTGT-PSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTP 335

Query: 165 ---FLTRRGRKSRSSPGDSPSAVSPNLSPS-ASPTSSRSN-SLTVPTPPGLDVCSGPPSP 219
               +TR    SR+SP   PS  SP  +PS ASPT S S  SLT     GL   + P   
Sbjct: 336 PRASITRT--PSRASPTGKPSTASPTGTPSRASPTGSPSTASLT-----GLSSTASPTGT 388

Query: 220 LPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRK--VSQGRLAPRPPPVEKSKEIA 277
            P A P  G  +  S         P G+  R    +     S  R  PR  P        
Sbjct: 389 PPRASPT-GTPSTASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTP---- 443

Query: 278 IEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPR 337
                       P  +P G     + +G  +  SP                   GSP   
Sbjct: 444 ------------PRASPTGTPSRASPTGTQSTASPT------------------GSPSTA 473

Query: 338 SPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEP 393
           SPT   +   P  S  R          + +K E   +++R P     +W      P
Sbjct: 474 SPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPTWTPSTASP 529



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 55/220 (25%), Positives = 76/220 (34%), Gaps = 30/220 (13%)

Query: 173 SRSSPGDSPSAVSPNLS-PSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEA 231
           SR+SP  +P   SP  S P AS +   S +L + TPP     + P   L      K D  
Sbjct: 216 SRASPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPR----ASPTGMLSRTSLTKMDST 271

Query: 232 DVSSPHPGEPNV--PKGLADRKQNDQ--RKVSQGRLAPRPPPVEKSKEIAIEQKENFDPL 287
              +  P  P+   P G   R          S  R+ PR  P       ++ + ++   +
Sbjct: 272 ASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASI 331

Query: 288 QYPETTPKGLAPVTNS----SGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDA 343
               T P+     T S    +GK +  SP   P  +             SP     T   
Sbjct: 332 S--RTPPRASITRTPSRASPTGKPSTASPTGTPSRA-------------SPTGSPSTASL 376

Query: 344 AGVGPPAS-QGRGPAGEPMG-PEAGSKAELPPTVSRPPLL 381
            G+   AS  G  P   P G P   S    PP  S   +L
Sbjct: 377 TGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGML 416



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 70/304 (23%), Positives = 96/304 (31%), Gaps = 69/304 (22%)

Query: 48  PEDEEPPGEPQAAQ--------SPAGQGPPTAGVSCSPTPTIVLTGDATSPEGETDKNLA 99
           P    P G P  A         SP G    T+      T +   T    SP G   +   
Sbjct: 389 PPRASPTGTPSTASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASP 448

Query: 100 NRVHSPHKRLSHRHLKVSTASLTSVDPAGHIIDLVNDQLPDISISEEDKKKNLALLEEAK 159
               S       +     T S ++  P G      +   P  S S     +  +     K
Sbjct: 449 TGTPSRASPTGTQSTASPTGSPSTASPTGS----PSTASPTGSPSRASLTRTPSRASLTK 504

Query: 160 LVSERFLTRRGRKSRSSPGDSPSAVSPNLSPSA-----SP-------TSSRSN------- 200
           + S   +TR    SR+SP  +PS  SP  SPS      SP       T SR++       
Sbjct: 505 MESTASITRT--PSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSR 562

Query: 201 -SLTVP-------TPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQ 252
            SLT P       TP  + +   PPS  P   P +      +SP      +P      K 
Sbjct: 563 ASLTTPSRASLTRTPSTVLLTRMPPSASPTGMPSR------TSP----TGMPSSALLTKM 612

Query: 253 NDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSP 312
           +    ++  R  PR  P E                  P  +P G  P  + +G     SP
Sbjct: 613 DSTASIT--RTPPRASPTETP----------------PRASPTGTPPRASPTGTPPRASP 654

Query: 313 QPGP 316
              P
Sbjct: 655 TGTP 658



 Score = 30.8 bits (68), Expect = 5.9
 Identities = 55/230 (23%), Positives = 77/230 (33%), Gaps = 46/230 (20%)

Query: 38  SQQEAAMPHIPEDEEPPGEPQAAQSPAGQGPPTAGVSCSPTPTIVLTGDATSPEGETDK- 96
           +Q  A+    P    P G P  A SP G  P  A ++ +P+   +   ++T+    T   
Sbjct: 460 TQSTASPTGSPSTASPTGSPSTA-SPTGS-PSRASLTRTPSRASLTKMESTASITRTPSR 517

Query: 97  -------NLANRVHSPHKRLSHRHLKVSTASLTSVDPAGHIIDLVNDQLPDISISEEDKK 149
                  + A+   SP   L+      S A+LT                   S++    +
Sbjct: 518 ASPTWTPSTASPTGSPSTALAMG--SPSRAALTRTPSRA-------------SLTRTPSR 562

Query: 150 KNLALLEEAKLV---SERFLTRR-------GRKSRSSPGDSPS----------AVSPNLS 189
            +L     A L    S   LTR        G  SR+SP   PS          A      
Sbjct: 563 ASLTTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITRTP 622

Query: 190 PSASPTSSRSNSLTVPTPPGLDVCSGPPSPLP-GAPPQKGDEADVSSPHP 238
           P ASPT +   +    TPP       PP   P G PP+       S   P
Sbjct: 623 PRASPTETPPRASPTGTPPRASPTGTPPRASPTGTPPRASPTGTPSRASP 672


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 66/246 (26%), Positives = 90/246 (36%), Gaps = 36/246 (14%)

Query: 176 SPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSS 235
           SP  SP   +P  SP ASP  S S +     PP L   + PP  +P +PP     +  ++
Sbjct: 402 SPPPSPPVQAP-FSPPASPPVSPSATPPSQAPPSL---AAPPLQVPPSPPASPPMSPSAT 457

Query: 236 PHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVE--KSKEIAIEQKENFDPL----QY 289
           P    P  P  LA       +   Q   A   PP++   S   +   +  F P       
Sbjct: 458 P---PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 514

Query: 290 PETTPKGLAPVTNSSGKMAL--------------NSPQPGPVESELGKQLLKTGWEGSPL 335
           P  TP   AP   ++  + +                P PGP  S  G +L      G P 
Sbjct: 515 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574

Query: 336 P--RSPTQDAAG---VGPPASQGRGP---AGEPMGPEAGSKAELPPTVSRPPLLRGLSWD 387
           P  RSP+   +G    G  +S    P    G   GPE G+ A  PP  +        +W 
Sbjct: 575 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS-PPPDAELAACHPAAWS 633

Query: 388 SGPEEP 393
            GP  P
Sbjct: 634 RGPAPP 639



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 63/237 (26%), Positives = 86/237 (36%), Gaps = 20/237 (8%)

Query: 175 SSPGDSPSAVSPNL-SPSASPTSSRSNS-----LTVPTPPGLDVCSGPPSPLPGAPPQKG 228
           S P   PS  + +L SP+   T S   S     L  P P      + PP   P +PP   
Sbjct: 317 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP 376

Query: 229 DEADVSSPHPGEPN---VPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENF- 284
             + +++P P  PN   V    A         V      P  PPV  S     +   +  
Sbjct: 377 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 436

Query: 285 -DPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDA 343
             PLQ P + P    P++ S    A   PQ  P  +    QL K   +  P   +P   A
Sbjct: 437 APPLQVPPSPPAS-PPMSPS----ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 491

Query: 344 AGVGPPASQGRGP----AGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPR 396
               P +  G+ P    A  PM P A    + PP ++ P L    S  + P    PR
Sbjct: 492 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 548



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 61/248 (24%), Positives = 81/248 (32%), Gaps = 53/248 (21%)

Query: 181 PSAVSP---NLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPH 237
           P  V+P   + +P+  P SS  + L  P+P      S PPSP   APP            
Sbjct: 273 PPQVTPPRKDAAPALGPLSS--SPLATPSP------SAPPSP--SAPPSL-------QTL 315

Query: 238 PGEPNVPKGLADRKQNDQRKVSQGRLAPRPP-------PVEKSKEIAIEQKENFDPLQYP 290
           P  P  P   A          +     P PP       P +    +A+       PLQ P
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP------PLQAP 369

Query: 291 ETTPKG--LAPVTNSSGK----------MALNSPQPGPVESELGKQLLKTGWEGSPLPRS 338
            + P    L+P+   S +           A  SP P P                S  P S
Sbjct: 370 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 429

Query: 339 PTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQ 398
               +    P       PA  PM P A    + PP ++ PPL           +P P+  
Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA--------KPPPQAP 481

Query: 399 KVLAKLPL 406
             LA  PL
Sbjct: 482 PALATPPL 489



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 62/247 (25%), Positives = 87/247 (35%), Gaps = 40/247 (16%)

Query: 167 TRRGRKSRSSPGD-SPSAVSPNLSPSASPTSSRSNSLTVPTPPGLD---------VCSGP 216
           TR  R   S  G+ +P A + +  P +SP   R++  T P P G           V  G 
Sbjct: 80  TRTSRPPASGRGERAPPAKNTSPGPVSSP--GRASGTTRPGPLGQKGLRISAEETVARGK 137

Query: 217 PSPLPGAPP-QKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAP--RP-PPVEK 272
            +  P       G   D S P PG P+    +A R +    +V   R AP  RP PP E 
Sbjct: 138 ATEAPKRSALSAGARRDTSGPTPGTPS--PAMARRSRAAGTEVGLPRPAPSARPRPPTEG 195

Query: 273 SKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELG--KQLLKTGW 330
            ++      E+        TT    A     S    L  P    + S         ++G 
Sbjct: 196 PRKSVSSASEH-------STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 248

Query: 331 EGSPLPRSPTQDA--------AGVGPPASQGRGPAGEPMGPEAGS-----KAELPPTVSR 377
                PR+P   +        A   P  +  R  A   +GP + S         PP+ S 
Sbjct: 249 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA 308

Query: 378 PPLLRGL 384
           PP L+ L
Sbjct: 309 PPSLQTL 315


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 53/244 (21%), Positives = 90/244 (36%), Gaps = 34/244 (13%)

Query: 53   PPGEPQAAQSP--AGQGPPTAGVSCSPTPTIVL-----TGDATSPEGETDKNLANRVHSP 105
            PP     ++SP  AG+     GV+  P P I +     T     P   +    +  V S 
Sbjct: 1033 PPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSS 1092

Query: 106  HKRLSHRHLKVSTASLTSVDPAGHIIDLVNDQLPDISISEEDKKKNLALLEEAKLVSERF 165
              +  H H   S++S +S   +G +    ++      +S          +  ++  S   
Sbjct: 1093 GSKSHHSH---SSSSSSSASTSGKMKSSKSEGSSSSKLSSS--------MYSSQGSSGSS 1141

Query: 166  LTRRGRKSRSSPGDSP--------SAVSPNLSPSASPTSSRSNSLTVPT--------PPG 209
             ++   +S   PG SP         + S  + P   P+S  + SL+ P         P G
Sbjct: 1142 QSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGG 1201

Query: 210  LDVCSGPPSPLPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPP 269
             D  + P  P+PG PP    ++ +SS   G        +   ++     S G L+ + PP
Sbjct: 1202 SDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPP 1261

Query: 270  VEKS 273
               S
Sbjct: 1262 SSNS 1265


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 69/234 (29%), Positives = 82/234 (35%), Gaps = 35/234 (14%)

Query: 207  PPGLDVCSGPPSPL--PGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLA 264
            PPG    +GPP P+   GAP  KG  A  S+  PG    P G A R          G   
Sbjct: 840  PPGPAGPAGPPGPIGNVGAPGAKG--ARGSAGPPGATGFP-GAAGRVGPPG---PSGNAG 893

Query: 265  PRPPPVEKSKEIAIEQKENFDPLQYP-ETTPKGLAPVTNSSGKMALNSPQPGPVESELGK 323
            P  PP    KE     +    P   P E  P G        G    + P   P       
Sbjct: 894  PPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAP------- 946

Query: 324  QLLKTGWEGSPLPRSPTQDAAGVGPPASQGR-------GPAGEP--MGPEAGSKAELPPT 374
                    G+P P+        VG P  +G        GP+GEP   GP   S    PP 
Sbjct: 947  --------GTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPG 998

Query: 375  VSRPPLLRGLSWDSGPE-EPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAK-APG 426
               PP L G   +SG E  PG          P A+ ++   G AG   A  APG
Sbjct: 999  PMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPG 1052



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 60/204 (29%), Positives = 76/204 (37%), Gaps = 31/204 (15%)

Query: 177  PGDSPSAVSPNLSPS----ASPTSSRSNSLTVPT-PPGLDVCSGPPSPLPGAPPQKGDEA 231
            PG+S    +P    S     SP +      T P  PPG     G P P+ G   + GD  
Sbjct: 1009 PGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPV-GPAGKSGDRG 1067

Query: 232  DVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSK-----EIAIEQKENFDP 286
            +     P  P  P G            ++G   P+ P  +K +     +  I+    F  
Sbjct: 1068 ETGPAGPAGPVGPVG------------ARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSG 1115

Query: 287  LQYPETTP--KGLAPVTNSSGKMALNSPQPGPVESELGKQLLK--TGWEGSPLPRSPTQD 342
            LQ P   P   G    + +SG      P PG   +  GK  L    G  G P PR  T D
Sbjct: 1116 LQGPPGPPGSPGEQGPSGASGPAGPRGP-PGSAGAP-GKDGLNGLPGPIGPPGPRGRTGD 1173

Query: 343  AAGVGPPASQGRGPAGEPMGPEAG 366
            A  VGPP     GP G P  P AG
Sbjct: 1174 AGPVGPPGPP--GPPGPPGPPSAG 1195



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 72/250 (28%), Positives = 94/250 (37%), Gaps = 47/250 (18%)

Query: 208 PGLDVCSGPPSPL-----PGAPPQKGDEADVSSPHPGEPNVP--KGLA--------DRKQ 252
           PG D  +GP  P      PG    KG   +     PGE  +P  KGL         D K 
Sbjct: 496 PGADGVAGPKGPAGERGSPGPAGPKGSPGEAG--RPGEAGLPGAKGLTGSPGSPGPDGKT 553

Query: 253 NDQRKVSQ-GRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNS 311
                  Q GR  P  PP  + +            + +P   PKG A     +G+  +  
Sbjct: 554 GPPGPAGQDGRPGPPGPPGARGQA---------GVMGFPG--PKGAAGEPGKAGERGVPG 602

Query: 312 PQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQG----RGPAGEPMGPEAGS 367
           P PG V    GK   + G +G P P  P  +    GP  S G     GPAG P   EAG 
Sbjct: 603 P-PGAV-GPAGKDG-EAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPP--GEAGK 657

Query: 368 KAE--LPPTVSRPPLL-----RGLSWDSGPE-EPGPRLQKVLAKLPLAEEEKRFAGKAGG 419
             E  +P  +  P        RG   + G +  PGP   +     P  +  K  AG  G 
Sbjct: 658 PGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGA 717

Query: 420 KLAK-APGLK 428
             ++ APGL+
Sbjct: 718 PGSQGAPGLQ 727



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 62/234 (26%), Positives = 86/234 (36%), Gaps = 37/234 (15%)

Query: 181  PSAVSPNLSPSASPTSSRSNSLTVPT----PPGLDVCSGPPSPLPGAPPQKGDE-ADVSS 235
            P   S N  P   P  +       P     P G     GPP P PG   +KG   AD  +
Sbjct: 885  PPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGP-PGPAGEKGSPGADGPA 943

Query: 236  PHPGEPNVPKGLADRK-------QNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQ 288
              PG P  P+G+A ++       Q  +R    G   P   P ++    A  ++    P+ 
Sbjct: 944  GAPGTPG-PQGIAGQRGVVGLPGQRGERGFP-GLPGPSGEPGKQGPSGASGERGPPGPMG 1001

Query: 289  YPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGP 348
                 P GLA     SG+      +  P            G +GSP  +    +    GP
Sbjct: 1002 -----PPGLAGPPGESGREGAPGAEGSP------------GRDGSPGAKGDRGETGPAGP 1044

Query: 349  PASQGRGPAGEPMGP--EAGSKAELPPTVSRPPLLRGLSWDSGPEEP-GPRLQK 399
            P + G   A  P+GP  ++G + E  P     P+  G     GP  P GPR  K
Sbjct: 1045 PGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPV--GPVGARGPAGPQGPRGDK 1096



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 62/227 (27%), Positives = 77/227 (33%), Gaps = 44/227 (19%)

Query: 205 PTPPGLDVCSGPPSPL--PGAPPQKGDEADVSSP-HPGEPNVP-----------KGLADR 250
           P  PG    SGP  P   PG P + GD+ +   P  PGE   P            GL   
Sbjct: 205 PGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGM 264

Query: 251 KQN------DQRKVSQGRLAPRPPPVEKSKEIAIEQK-------ENFDPLQYPETTPKGL 297
           K +      D  K   G   P+  P    +  A  Q        E   P        +G 
Sbjct: 265 KGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGN 324

Query: 298 APVTNSSGKMALNSPQ-----PGPV--ESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPA 350
              T ++G      P      PG V  + E G Q    G  GS  P+    +    GPP 
Sbjct: 325 DGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQ----GPRGSEGPQGVRGEP---GPPG 377

Query: 351 SQGR-GPAGEPM--GPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPG 394
             G  GPAG P   G      A   P ++  P   G    SGP+ PG
Sbjct: 378 PAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPG 424



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 60/241 (24%), Positives = 76/241 (31%), Gaps = 45/241 (18%)

Query: 169 RGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGP------------ 216
           RG      PG  P     +  P A  +   + +   P P G+    GP            
Sbjct: 415 RGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGE 474

Query: 217 --PSPLPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSK 274
             P+ LPG P ++G       P       PKG A  +       S G   P+  P E  +
Sbjct: 475 PGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERG------SPGPAGPKGSPGEAGR 528

Query: 275 EIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSP 334
                      P +      KGL     S G      P PGP   +        G  G P
Sbjct: 529 -----------PGEAGLPGAKGLTGSPGSPGPDGKTGP-PGPAGQD--------GRPGPP 568

Query: 335 LPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPG 394
            P      A  +G P    +G AGEP G         PP    P    G +   GP  PG
Sbjct: 569 GPPGARGQAGVMGFPGP--KGAAGEP-GKAGERGVPGPPGAVGPAGKDGEAGAQGP--PG 623

Query: 395 P 395
           P
Sbjct: 624 P 624



 Score = 38.9 bits (89), Expect = 0.022
 Identities = 64/227 (28%), Positives = 76/227 (33%), Gaps = 42/227 (18%)

Query: 181  PSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPP--SPLPGAPPQKGDEADVSSPHP 238
            P    P+  P     S  S     P P G    +GPP  S   GAP  +G         P
Sbjct: 973  PGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGS--------P 1024

Query: 239  GEPNVPKGLADRKQNDQRKVSQGRLAPRPP----PVEKSKEIAIEQKENFDPLQYPETTP 294
            G    P    DR +           AP  P    P  KS +               ET P
Sbjct: 1025 GRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRG-------------ETGP 1071

Query: 295  KGLAPVTNSSGKMALNSPQ-PGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQG 353
             G A      G      PQ P   + E G+Q    G  G    R  +      GPP S G
Sbjct: 1072 AGPAGPVGPVGARGPAGPQGPRGDKGETGEQ----GDRGIKGHRGFSGLQGPPGPPGSPG 1127

Query: 354  -RGPAGE--PMGPEAGSKAELPPTVSRPPLLRGLSWDSGP-EEPGPR 396
             +GP+G   P GP        PP  +  P   GL+   GP   PGPR
Sbjct: 1128 EQGPSGASGPAGPRG------PPGSAGAPGKDGLNGLPGPIGPPGPR 1168



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 60/228 (26%), Positives = 74/228 (32%), Gaps = 79/228 (34%)

Query: 204 VPTPPGLDVCSGPPSPLPGAPPQKGDEAD-------------VSSPHPGEPNVPKGLADR 250
           +P  PGL    GPP P PG P   G+ A              +S P P  P+ P+GL   
Sbjct: 134 IPGQPGLPGPPGPPGP-PGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGL--- 189

Query: 251 KQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALN 310
                         P PP                 P       P G      +SG M   
Sbjct: 190 --------------PGPPGA---------------PGPQGFQGPPGEPGEPGASGPMGPR 220

Query: 311 SPQPGPV-----ESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGR----------- 354
            P PGP      + E GK   + G  G P P+         G P  +G            
Sbjct: 221 GP-PGPPGKNGDDGEAGKP-GRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKG 278

Query: 355 -----GPAGEPMGP-EAGSKAELPPTVSRPPLLRGLSWDSG-PEEPGP 395
                GP GEP  P E G+  ++ P        RGL  + G P  PGP
Sbjct: 279 DAGPAGPKGEPGSPGENGAPGQMGP--------RGLPGERGRPGAPGP 318



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 60/233 (25%), Positives = 78/233 (33%), Gaps = 43/233 (18%)

Query: 192 ASPTSSRSNSLTVPTP--PGLDVCSGPPSPLPGAPPQKGDEADVSSP----------HPG 239
           A P   R       +P   GL   +GPP    G P ++G   D+ +P           PG
Sbjct: 625 AGPAGERGEQGPAGSPGFQGLPGPAGPPGEA-GKPGEQGVPGDLGAPGPSGARGERGFPG 683

Query: 240 EPNV--------PKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEI-AIEQKENFDPLQYP 290
           E  V        P+G      ND  K   G  AP  P  + +  +  +  +     L  P
Sbjct: 684 ERGVQGPPGPAGPRGANGAPGNDGAKGDAG--APGAPGSQGAPGLQGMPGERGAAGLPGP 741

Query: 291 -----ETTPKGLAPVTNSSGKMALNSP--QPGPVESELGKQLLKTGWEGSPLPRSPTQDA 343
                +  PKG        G   L  P   PGP  +         G +G   P  P    
Sbjct: 742 KGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAP--------GDKGESGPSGPAGPT 793

Query: 344 AGVGPPASQGR-GPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGP 395
              G P  +G  GP G P G      A+  P     P   G   D+GP  PGP
Sbjct: 794 GARGAPGDRGEPGPPG-PAGFAGPPGADGQPGAKGEPGDAGAKGDAGP--PGP 843



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 35/110 (31%), Positives = 44/110 (40%), Gaps = 21/110 (19%)

Query: 328 TGWEGSPLPRSPTQDAAGVGPPASQG----RGPAGEPMGPEAGSKAELPPTVSRPPLLRG 383
           TG    P P  P+      GPP + G    +GP GEP  P A      P     PP   G
Sbjct: 172 TGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASG----PMGPRGPPGPPG 227

Query: 384 LSWDSG-------PEE---PGPRLQKVL---AKLPLAEEEKRFAGKAGGK 420
            + D G       P E   PGP+  + L   A LP  +  + F+G  G K
Sbjct: 228 KNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAK 277


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.127    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,348,463
Number of Sequences: 37866
Number of extensions: 2680173
Number of successful extensions: 33261
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 376
Number of HSP's successfully gapped in prelim test: 1315
Number of HSP's that attempted gapping in prelim test: 19081
Number of HSP's gapped (non-prelim): 11052
length of query: 903
length of database: 18,247,518
effective HSP length: 111
effective length of query: 792
effective length of database: 14,044,392
effective search space: 11123158464
effective search space used: 11123158464
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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