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Search of human proteins with 148728160
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148728160 protein tyrosine phosphatase, receptor type, J
isoform 2 precursor [Homo sapiens]
(539 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148728160 protein tyrosine phosphatase, receptor type, J isof... 1082 0.0
gi|148728162 protein tyrosine phosphatase, receptor type, J isof... 1079 0.0
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 102 7e-22
gi|241896924 protein tyrosine phosphatase, receptor type, H isof... 76 9e-14
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] 70 6e-12
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] 70 6e-12
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] 70 6e-12
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] 70 6e-12
gi|153946395 tenascin C precursor [Homo sapiens] 66 9e-11
gi|241896926 protein tyrosine phosphatase, receptor type, H isof... 64 3e-10
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] 64 5e-10
gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] 64 5e-10
gi|157384973 tenascin R [Homo sapiens] 60 7e-09
gi|62988324 tenascin N [Homo sapiens] 60 7e-09
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 50 4e-06
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 46 8e-05
gi|157311649 neogenin homolog 1 [Homo sapiens] 46 1e-04
gi|110349719 titin isoform N2-A [Homo sapiens] 45 2e-04
gi|110349717 titin isoform novex-2 [Homo sapiens] 45 2e-04
gi|110349713 titin isoform novex-1 [Homo sapiens] 45 2e-04
gi|110349715 titin isoform N2-B [Homo sapiens] 45 2e-04
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 44 3e-04
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 44 3e-04
gi|110431348 deleted in colorectal carcinoma [Homo sapiens] 44 4e-04
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 44 5e-04
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 44 5e-04
gi|20665034 tenascin XB isoform 2 [Homo sapiens] 42 0.002
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 41 0.003
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens] 41 0.003
gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo ... 40 0.005
>gi|148728160 protein tyrosine phosphatase, receptor type, J isoform
2 precursor [Homo sapiens]
Length = 539
Score = 1082 bits (2797), Expect = 0.0
Identities = 539/539 (100%), Positives = 539/539 (100%)
Query: 1 MKPAAREARLPPRSPGLRWALPLLLLLLRLGQILCAGGTPSPIPDPSVATVATGENGITQ 60
MKPAAREARLPPRSPGLRWALPLLLLLLRLGQILCAGGTPSPIPDPSVATVATGENGITQ
Sbjct: 1 MKPAAREARLPPRSPGLRWALPLLLLLLRLGQILCAGGTPSPIPDPSVATVATGENGITQ 60
Query: 61 ISSTAESFHKQNGTGTPQVETNTSEDGESSGANDSLRTPEQGSNGTDGASQKTPSSTGPS 120
ISSTAESFHKQNGTGTPQVETNTSEDGESSGANDSLRTPEQGSNGTDGASQKTPSSTGPS
Sbjct: 61 ISSTAESFHKQNGTGTPQVETNTSEDGESSGANDSLRTPEQGSNGTDGASQKTPSSTGPS 120
Query: 121 PVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQPWCNITGLRPAT 180
PVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQPWCNITGLRPAT
Sbjct: 121 PVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQPWCNITGLRPAT 180
Query: 181 SYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNGTASCRVLL 240
SYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNGTASCRVLL
Sbjct: 181 SYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNGTASCRVLL 240
Query: 241 ESIGSHEELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSR 300
ESIGSHEELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSR
Sbjct: 241 ESIGSHEELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSR 300
Query: 301 AGSPTAPVHDESLVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAI 360
AGSPTAPVHDESLVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAI
Sbjct: 301 AGSPTAPVHDESLVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAI 360
Query: 361 EFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAV 420
EFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAV
Sbjct: 361 EFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAV 420
Query: 421 IPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAE 480
IPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAE
Sbjct: 421 IPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAE 480
Query: 481 SFQMHITQEGAGNSRVEITTNQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRTG 539
SFQMHITQEGAGNSRVEITTNQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRTG
Sbjct: 481 SFQMHITQEGAGNSRVEITTNQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRTG 539
>gi|148728162 protein tyrosine phosphatase, receptor type, J isoform
1 precursor [Homo sapiens]
Length = 1337
Score = 1079 bits (2791), Expect = 0.0
Identities = 538/538 (100%), Positives = 538/538 (100%)
Query: 1 MKPAAREARLPPRSPGLRWALPLLLLLLRLGQILCAGGTPSPIPDPSVATVATGENGITQ 60
MKPAAREARLPPRSPGLRWALPLLLLLLRLGQILCAGGTPSPIPDPSVATVATGENGITQ
Sbjct: 1 MKPAAREARLPPRSPGLRWALPLLLLLLRLGQILCAGGTPSPIPDPSVATVATGENGITQ 60
Query: 61 ISSTAESFHKQNGTGTPQVETNTSEDGESSGANDSLRTPEQGSNGTDGASQKTPSSTGPS 120
ISSTAESFHKQNGTGTPQVETNTSEDGESSGANDSLRTPEQGSNGTDGASQKTPSSTGPS
Sbjct: 61 ISSTAESFHKQNGTGTPQVETNTSEDGESSGANDSLRTPEQGSNGTDGASQKTPSSTGPS 120
Query: 121 PVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQPWCNITGLRPAT 180
PVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQPWCNITGLRPAT
Sbjct: 121 PVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQPWCNITGLRPAT 180
Query: 181 SYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNGTASCRVLL 240
SYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNGTASCRVLL
Sbjct: 181 SYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNGTASCRVLL 240
Query: 241 ESIGSHEELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSR 300
ESIGSHEELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSR
Sbjct: 241 ESIGSHEELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSR 300
Query: 301 AGSPTAPVHDESLVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAI 360
AGSPTAPVHDESLVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAI
Sbjct: 301 AGSPTAPVHDESLVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAI 360
Query: 361 EFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAV 420
EFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAV
Sbjct: 361 EFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAV 420
Query: 421 IPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAE 480
IPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAE
Sbjct: 421 IPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAE 480
Query: 481 SFQMHITQEGAGNSRVEITTNQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRT 538
SFQMHITQEGAGNSRVEITTNQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRT
Sbjct: 481 SFQMHITQEGAGNSRVEITTNQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRT 538
Score = 108 bits (271), Expect = 9e-24
Identities = 105/406 (25%), Positives = 165/406 (40%), Gaps = 64/406 (15%)
Query: 173 ITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSW----- 227
+ GL P T Y ++ N T G P+ I+ T I V D+ L W
Sbjct: 332 LVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDN 391
Query: 228 -SNGNGTASCRVLLESIGSHEELTQDSRLQVNISGLKPGVQYNIN--PYLLQSNKTKGDP 284
S+ N T V E+ S+ +++ + I GL+ YNI P L GD
Sbjct: 392 ESSSNYTYKIHVAGETDSSNLNVSEPRAV---IPGLRSSTFYNITVCPVL-------GDI 441
Query: 285 LGTEGGLDASNTERSRAGSPTAPVHD--ESLVGPVDPSSGQQSRDTE------------- 329
GT G L +P PV D ++V + S D E
Sbjct: 442 EGTPGFLQVH--------TPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGN 493
Query: 330 ----------VLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISA 379
+++ GL PGT+Y + + NGTEG + + RT VFD+ V ++
Sbjct: 494 SRVEITTNQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRTVPSAVFDIHVVYVTT 553
Query: 380 TSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLG 439
T + L WK D +S Y Y + + + S++ + + + GL T YNIT+ P +
Sbjct: 554 TEMWLDWKSPD--GASEYVYHLVIESKHGSNHTSTYDKAITLQGLIPGTLYNITISPEVD 611
Query: 440 DIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHD----AESFQMHITQEGAGNSR 495
+ G P +T P VS+ V+ +TT L+W + D S+ + I + G ++
Sbjct: 612 HVWGDPNSTAQYTRPSNVSNIDVS-TNTTAATLSWQNFDDASPTYSYCLLIEKAGNSSNA 670
Query: 496 VEITTNQSI---IIGGLFPGTKYCFEI---VPKGPNGTEGASRTVC 535
++ T+ I + L PG+ Y EI V G E ++ C
Sbjct: 671 TQVVTDIGITDATVTELIPGSSYTVEIFAQVGDGIKSLEPGRKSFC 716
Score = 106 bits (265), Expect = 5e-23
Identities = 81/245 (33%), Positives = 114/245 (46%), Gaps = 17/245 (6%)
Query: 40 PSPIPDPSVATVATGENGITQISSTAESFHK---QNGTGTPQVETNTSED----GESSGA 92
P P+ D V V+T E G+ S AESF Q G G +VE T++ G G
Sbjct: 454 PVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVEITTNQSIIIGGLFPGT 513
Query: 93 NDSLRTPEQGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYV 152
+G NGT+GAS+ + T PS VFDI V ++ T + L WKS D ASEY Y
Sbjct: 514 KYCFEIVPKGPNGTEGASRTVCNRTVPSAVFDIHVVYVTTTEMWLDWKSPD-GASEYVYH 572
Query: 153 VKHKMENEKTITVVHQPWCNITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSD 212
+ + ++ T + + GL P T Y +I+P + + WGDP T P VS+
Sbjct: 573 LVIESKHGSNHTSTYDKAITLQGLIPGTLYNITISPEV-DHVWGDPNSTAQYTRPSNVSN 631
Query: 213 LRVALTGVRKAALSWSN---GNGTASCRVLLESIGSHEELTQ----DSRLQVNISGLKPG 265
+ V+ T A LSW N + T S +L+E G+ TQ ++ L PG
Sbjct: 632 IDVS-TNTTAATLSWQNFDDASPTYSYCLLIEKAGNSSNATQVVTDIGITDATVTELIPG 690
Query: 266 VQYNI 270
Y +
Sbjct: 691 SSYTV 695
Score = 43.9 bits (102), Expect = 4e-04
Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 7/86 (8%)
Query: 454 PVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVEITTNQSIIIGGLFPGT 513
P P+ D V V+T E G+ S AESF Q G G +VE T++ G G
Sbjct: 40 PSPIPDPSVATVATGENGITQISSTAESFHK---QNGTGTPQVETNTSED----GESSGA 92
Query: 514 KYCFEIVPKGPNGTEGASRTVCNRTG 539
+G NGT+GAS+ + TG
Sbjct: 93 NDSLRTPEQGSNGTDGASQKTPSSTG 118
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 102 bits (255), Expect = 7e-22
Identities = 126/469 (26%), Positives = 195/469 (41%), Gaps = 41/469 (8%)
Query: 105 GTDGASQKTPSSTGP----SPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENE 160
G + A+ T TGP SPV D++A + V ++W S A++Y+ +V+ E
Sbjct: 490 GHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSW-SPVPGATQYRIIVRSTQGVE 548
Query: 161 KTITVV-HQPWCNITGLRPATSYVFSITPGIGNETWGDPRVIKVITEP---IPVSDLRVA 216
+T+ + Q ++ ++ SY ++ +G G V+ V EP + V LRV
Sbjct: 549 RTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPRE-GSASVLTVRREPETPLAVPGLRVV 607
Query: 217 LTGVRKAALSWSNGNGTASCRVLLESIGSHEELTQD---SRLQVNISGLKPGVQYNINPY 273
++ + ++W G + R+ S GS E +Q +I+GL+PG Y +
Sbjct: 608 VSDATRVRVAWGPVPGASGFRISW-STGSGPESSQTLPPDSTATDITGLQPGTTYQVAVS 666
Query: 274 LLQSNK--------TKGDPLGTEGGLDASNTERSRA--------GSPTAPVHDESLVGPV 317
+L+ + + DPLG + + S G+ V S GP
Sbjct: 667 VLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRVPGATGYRVSWHSAHGP- 725
Query: 318 DPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAV-- 375
+ S T L GLEP T Y V + A G +G P ++ RT V V+ +
Sbjct: 726 EKSQLVSGEATVAELDGLEPDTEYTVHVRAHVA-GVDGPPASVVVRTAPEPVGRVSRLQI 784
Query: 376 -NISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITV 434
N S+ L + W ++ + G L + A I GL Y++ V
Sbjct: 785 LNASSDVLRITWVGVTGATAYRLAWGRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRV 844
Query: 435 CPVLGDIEGTPGFLQVHTPP-VPVSDFRVTVVSTTE--IGLAWSS-HDAESFQMHITQEG 490
++GD EGTP + V TPP P + + VV E + L W A+ F +H EG
Sbjct: 845 TALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQGFLLHWQPEG 904
Query: 491 A-GNSRVEITTNQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRT 538
SRV S + GL P T+Y + GP G EG S V RT
Sbjct: 905 GQEQSRVLGPELSSYHLDGLEPATQYRVRLSVLGPAG-EGPSAEVTART 952
Score = 64.3 bits (155), Expect = 3e-10
Identities = 99/448 (22%), Positives = 170/448 (37%), Gaps = 43/448 (9%)
Query: 108 GASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMEN-----EKT 162
G + + T S ++ V + PT+++L+W A Y ++ + E +K
Sbjct: 404 GPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEARG---YRLEWRRETGLEPPQKV 460
Query: 163 ITVVHQPWCNITGLRPATSYVFSITPGIGNETWGDPRVIKVITEP----IPVSDLRVALT 218
+ + GL+P T Y ++ + P + V T P PV+DL+
Sbjct: 461 VLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATV-VPTGPELPVSPVTDLQATEL 519
Query: 219 GVRKAALSWSNGNGTASCRVLLESIGSHEE--LTQDSRLQVNISGLKPGVQYNI------ 270
++ +SWS G R+++ S E + S+ ++ ++ G+ Y +
Sbjct: 520 PGQRVRVSWSPVPGATQYRIIVRSTQGVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARV 579
Query: 271 -----NPYLLQSNKTKGDPLGTEG----GLDASNTERSRAGSPTAPVHDESLVGPVDPSS 321
+ +L + PL G DA+ + P A S P S
Sbjct: 580 GPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGASGFRISWSTGSGPES 639
Query: 322 GQ--QSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAI-QVFDVTAVNIS 378
Q T + GL+PGT Y V S EG I RT+ + V V S
Sbjct: 640 SQTLPPDSTATDITGLQPGTTYQVAV-SVLRGREEGPAAVIVARTDPLGPVRTVHVTQAS 698
Query: 379 ATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPR-AVIPGLRSSTFYNITVCPV 437
++S+T+ W + ++ Y H A + S L E A + GL T Y + V
Sbjct: 699 SSSVTITW--TRVPGATGYRVSWHSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAH 756
Query: 438 LGDIEGTPGFLQVHTPPVP---VSDFRVTVVSTTEIGLAW-SSHDAESFQMHITQEGAGN 493
+ ++G P + V T P P VS ++ S+ + + W A ++++ + G
Sbjct: 757 VAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATAYRLAWGRSEGGP 816
Query: 494 SRVEIT--TNQSIIIGGLFPGTKYCFEI 519
R +I S I GL G Y +
Sbjct: 817 MRHQILPGNTDSAEIRGLEGGVSYSVRV 844
Score = 62.8 bits (151), Expect = 8e-10
Identities = 48/193 (24%), Positives = 82/193 (42%), Gaps = 5/193 (2%)
Query: 327 DTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIW 386
+T V L GL P T Y TV + AN G+ + RT A++ ++T N +A SL + W
Sbjct: 289 ETSVRLRGLRPLTEYQVTVIALYANSI-GEAVSGTARTTALEGPELTIQNTTAHSLLVAW 347
Query: 387 KVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPG 446
+ + T+++ G T L + ++ L T Y +TV + G G
Sbjct: 348 RSVPGATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPAT 407
Query: 447 FLQVHTPPVPVSDFRVTVVSTTEIGLAWS-SHDAESFQMHITQEGAGNSRVEITTNQSII 505
L T R ++ T I L+W+ +A +++ +E ++ +
Sbjct: 408 SLMARTDASVEQTLRPVILGPTSILLSWNLVPEARGYRLEWRRETGLEPPQKVVLPSDVT 467
Query: 506 ---IGGLFPGTKY 515
+ GL PGT+Y
Sbjct: 468 RYQLDGLQPGTEY 480
Score = 53.5 bits (127), Expect = 5e-07
Identities = 99/419 (23%), Positives = 151/419 (36%), Gaps = 72/419 (17%)
Query: 172 NITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPI-PVSDLRVALTGVRKAALSWSNG 230
+ITGL+P T+Y +++ G E G VI T+P+ PV + V ++W+
Sbjct: 651 DITGLQPGTTYQVAVSVLRGREE-GPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRV 709
Query: 231 NGTASCRVLLESIGSHE--ELTQDSRLQVNISGLKPGVQYNIN----------PYLLQSN 278
G RV S E +L + GL+P +Y ++ P
Sbjct: 710 PGATGYRVSWHSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPASVVV 769
Query: 279 KTKGDPLG-----------------TEGGLDASNTERSRAG-SPTAPVHDESLVGPVDPS 320
+T +P+G T G+ + R G S P+ + L G D +
Sbjct: 770 RTAPEPVGRVSRLQILNASSDVLRITWVGVTGATAYRLAWGRSEGGPMRHQILPGNTDSA 829
Query: 321 SGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTN-----AIQVFDVTAV 375
+ GLE G Y+ V + + EG P +I T A+ V V
Sbjct: 830 E----------IRGLEGGVSYSVRVTALVGD-REGTPVSIVVTTPPEAPPALGTLHV--V 876
Query: 376 NISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAV---IPGLRSSTFYNI 432
SL L W+ + +H E V P + GL +T Y +
Sbjct: 877 QRGEHSLRLRWEPVPRAQG----FLLHWQPEGGQEQSRVLGPELSSYHLDGLEPATQYRV 932
Query: 433 TVCPVLGDIEGTPGF---LQVHTPPVPVSDFRVTVVSTTEIGLAWSSHD-AESFQMHIT- 487
+ VLG P + +P VP + RV S + LAW+ A S+ +
Sbjct: 933 RLS-VLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPVSRASSYILSWRP 991
Query: 488 -----QEGAGNSRVEITTNQSIIIGGLFPGTKYCFEIVP--KGPNGTEGA--SRTVCNR 537
QE G+ + + S + GL PG Y F + P G G E + VC R
Sbjct: 992 LRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPVCPR 1050
Score = 46.6 bits (109), Expect = 6e-05
Identities = 85/376 (22%), Positives = 134/376 (35%), Gaps = 41/376 (10%)
Query: 173 ITGLRPATSYVFSITP----GIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWS 228
+ GLRP T Y ++ IG G R T + +L + T ++W
Sbjct: 294 LRGLRPLTEYQVTVIALYANSIGEAVSGTAR-----TTALEGPELTIQNTTAHSLLVAWR 348
Query: 229 NGNGTASCRVLLESIGSHEELTQD---SRLQVNISGLKPGVQYNINPYLLQSNKTKGDPL 285
+ G RV + Q+ + V + L+PG Y + L ++ G
Sbjct: 349 SVPGATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTL-FGRSVGPAT 407
Query: 286 GTEGGLDAS--NTERSRAGSPTAPVHDESLV--------------GPVDPSSGQQSRD-T 328
DAS T R PT+ + +LV G P D T
Sbjct: 408 SLMARTDASVEQTLRPVILGPTSILLSWNLVPEARGYRLEWRRETGLEPPQKVVLPSDVT 467
Query: 329 EVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVT---AVNISATSLTLI 385
L GL+PGT Y T+Y+ P + + V VT A + + +
Sbjct: 468 RYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVS 527
Query: 386 WKVSDNESSSNYTYKIH-VAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGT 444
W S ++ Y + G + L S+ + +++ Y + V +G EG+
Sbjct: 528 W--SPVPGATQYRIIVRSTQGVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGS 585
Query: 445 PGFLQVH---TPPVPVSDFRVTVVSTTEIGLAWSS-HDAESFQMH-ITQEGAGNSRVEIT 499
L V P+ V RV V T + +AW A F++ T G +S+
Sbjct: 586 ASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGASGFRISWSTGSGPESSQTLPP 645
Query: 500 TNQSIIIGGLFPGTKY 515
+ + I GL PGT Y
Sbjct: 646 DSTATDITGLQPGTTY 661
Score = 33.5 bits (75), Expect = 0.51
Identities = 28/112 (25%), Positives = 44/112 (39%), Gaps = 12/112 (10%)
Query: 86 DGESSGANDSLRTPEQGSNGTDGASQKTPSSTGPS-PVFDIKAVSISPTNVILTWKSNDT 144
DG +R G G +++ T + P P +++ V S +V L W
Sbjct: 922 DGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPVSR 981
Query: 145 AASEYKYVVKHKMENEKTITVVHQPWC--------NITGLRPATSYVFSITP 188
A+S Y++ + V P +TGL P SY+FS+TP
Sbjct: 982 ASS---YILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTP 1030
>gi|241896924 protein tyrosine phosphatase, receptor type, H isoform
1 precursor [Homo sapiens]
Length = 1115
Score = 75.9 bits (185), Expect = 9e-14
Identities = 106/494 (21%), Positives = 187/494 (37%), Gaps = 51/494 (10%)
Query: 53 TGENGITQISSTAESFHKQNGTGTPQVETNTSEDGESSGANDSLRTPEQGSNGTDGASQK 112
TG+ G T+ +T + +G G + T S E G N S+ T
Sbjct: 68 TGDGGTTETRNTTATNVTVDGLGPGSLYT-CSVWVEKDGVNSSVGT-------------- 112
Query: 113 TPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYK-YVVKHKMENEK--TITVVHQP 169
++T P+PV +++ + + +++ LTW+ D + Y V++ + + T + H
Sbjct: 113 VTTATAPNPVRNLRVEAQTNSSIALTWEVPDGPDPQNSTYGVEYTGDGGRAGTRSTAHT- 171
Query: 170 WCNIT--GLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSW 227
NIT GL P Y FS+ G N T PV +LRV +LSW
Sbjct: 172 --NITVDGLEPGCLYAFSMWVG-KNGINSSRETRNATTAHNPVRNLRVEAQTTSSISLSW 228
Query: 228 SNGNGT----ASCRVLLESIGSHEELTQDSRLQVNISGLKPGVQYNINPYL--------- 274
+GT ++ V G E + +V + GL PG Y + ++
Sbjct: 229 EVPDGTDPQNSTYCVQCTGDGGRTETRNTTDTRVTVDGLGPGSLYTCSVWVEKDGVNSSV 288
Query: 275 -LQSNKTKGDP---LGTEGGLDAS---NTERSRAGSPTAPVHDESLVGPVDPSSGQQSRD 327
+ ++ T +P L E ++S E P + G + + +
Sbjct: 289 EIVTSATAPNPVRNLTVEAQTNSSIALTWEVPDGPDPQNSTYGVEYTGDGGRAGTRSTAH 348
Query: 328 TEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWK 387
T + + LEPG Y +V+ NG + T V ++ + +S+ L W+
Sbjct: 349 TNITVDRLEPGCLYVFSVWV-GKNGINSSRETRNATTAPNPVRNLHMETQTNSSIALCWE 407
Query: 388 VSDNESSSNYTYKIHVAGETDSSNL-NVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPG 446
V D +YTY + G+ + N + L T Y +V G+
Sbjct: 408 VPDGPYPQDYTYWVEYTGDGGGTETRNTTNTSVTAERLEPGTLYTFSVWAEKNGARGSRQ 467
Query: 447 FLQVHTPPVPVSDFRVTVVSTTEIGLAWSS-----HDAESFQMHITQEGAGNSRVEITTN 501
+ + T P V+ + + I L W++ + S+ + +EG + R + T+
Sbjct: 468 NVSISTVPNAVTSLSKQDWTNSTIALRWTAPQGPGQSSYSYWVSWVREGMTDPRTQSTSG 527
Query: 502 QSIIIGGLFPGTKY 515
I + L G+ Y
Sbjct: 528 TDITLKELEAGSLY 541
Score = 75.1 bits (183), Expect = 2e-13
Identities = 95/450 (21%), Positives = 171/450 (38%), Gaps = 44/450 (9%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQPWCNIT--GL 176
P+P ++ + + +++ L+W+ D S+ + T + N+T GL
Sbjct: 30 PNPGRNLTVETQTTSSISLSWEVPDGLDSQNSNYWVQCTGDGGTTETRNTTATNVTVDGL 89
Query: 177 RPATSYVFSI---TPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNG- 232
P + Y S+ G+ + + T P PV +LRV AL+W +G
Sbjct: 90 GPGSLYTCSVWVEKDGVNSSVG----TVTTATAPNPVRNLRVEAQTNSSIALTWEVPDGP 145
Query: 233 ---TASCRVLLESIGSHEELTQDSRLQVNISGLKPGVQYNINPYL----------LQSNK 279
++ V G + + + GL+PG Y + ++ ++
Sbjct: 146 DPQNSTYGVEYTGDGGRAGTRSTAHTNITVDGLEPGCLYAFSMWVGKNGINSSRETRNAT 205
Query: 280 TKGDP---LGTEGGLDASNTERSRAGSPTAPVHDESLV---GPVDPSSGQQSRDTEVLLV 333
T +P L E +S + T P + V G + + + DT V +
Sbjct: 206 TAHNPVRNLRVEAQTTSSISLSWEVPDGTDPQNSTYCVQCTGDGGRTETRNTTDTRVTVD 265
Query: 334 GLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISA---TSLTLIWKVSD 390
GL PG+ Y +V+ + +G ++E T+A V + + A +S+ L W+V D
Sbjct: 266 GLGPGSLYTCSVWVEK----DGVNSSVEIVTSATAPNPVRNLTVEAQTNSSIALTWEVPD 321
Query: 391 NESSSNYTYKIHVAGETDSSNL-NVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQ 449
N TY + G+ + + + + L Y +V I +
Sbjct: 322 GPDPQNSTYGVEYTGDGGRAGTRSTAHTNITVDRLEPGCLYVFSVWVGKNGINSSRETRN 381
Query: 450 VHTPPVPVSDFRVTVVSTTEIGLAWSSHDAE-----SFQMHITQEGAGNSRVEITTNQSI 504
T P PV + + + + I L W D ++ + T +G G + TTN S+
Sbjct: 382 ATTAPNPVRNLHMETQTNSSIALCWEVPDGPYPQDYTYWVEYTGDGGG-TETRNTTNTSV 440
Query: 505 IIGGLFPGTKYCFEIVPKGPNGTEGASRTV 534
L PGT Y F + + NG G+ + V
Sbjct: 441 TAERLEPGTLYTFSVWAE-KNGARGSRQNV 469
Score = 72.8 bits (177), Expect = 8e-13
Identities = 100/488 (20%), Positives = 182/488 (37%), Gaps = 80/488 (16%)
Query: 44 PDPSVATVA---TGENGITQISSTAESFHKQNGTGTPQVETNTSEDGESSGANDSLRTPE 100
PDP +T TG+ G STA TN + DG G + +
Sbjct: 145 PDPQNSTYGVEYTGDGGRAGTRSTAH--------------TNITVDGLEPGCLYAF-SMW 189
Query: 101 QGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSND-TAASEYKYVVKHKMEN 159
G NG + + + ++T +PV +++ + + +++ L+W+ D T Y V+ +
Sbjct: 190 VGKNGINSSRETRNATTAHNPVRNLRVEAQTTSSISLSWEVPDGTDPQNSTYCVQCTGDG 249
Query: 160 EKTITV-VHQPWCNITGLRPATSYVFSI---TPGIGNETWGDPRVIKVITEPIPVSDLRV 215
+T T + GL P + Y S+ G+ + ++ T P PV +L V
Sbjct: 250 GRTETRNTTDTRVTVDGLGPGSLYTCSVWVEKDGVNSSV----EIVTSATAPNPVRNLTV 305
Query: 216 ALTGVRKAALSWSNGNG----TASCRVLLESIGSHEELTQDSRLQVNISGLKPGVQYNIN 271
AL+W +G ++ V G + + + L+PG Y +
Sbjct: 306 EAQTNSSIALTWEVPDGPDPQNSTYGVEYTGDGGRAGTRSTAHTNITVDRLEPGCLYVFS 365
Query: 272 PYLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAP-----VHDESLV------------ 314
++ G + N+ R + TAP +H E+
Sbjct: 366 VWV---------------GKNGINSSRETRNATTAPNPVRNLHMETQTNSSIALCWEVPD 410
Query: 315 GP-----------VDPSSGQQSRDT---EVLLVGLEPGTRYNATVYSQAANGTEGQPQAI 360
GP G ++R+T V LEPGT Y +V+++ NG G Q +
Sbjct: 411 GPYPQDYTYWVEYTGDGGGTETRNTTNTSVTAERLEPGTLYTFSVWAEK-NGARGSRQNV 469
Query: 361 EFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVA--GETDSSNLNVSEPR 418
T V ++ + + +++ L W S+Y+Y + G TD + S
Sbjct: 470 SISTVPNAVTSLSKQDWTNSTIALRWTAPQGPGQSSYSYWVSWVREGMTDPRTQSTSGTD 529
Query: 419 AVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHD 478
+ L + + Y++TV ++ G L T P V+D + + + L W +
Sbjct: 530 ITLKELEAGSLYHLTVWAERNEVRGYNSTLTAATAPNEVTDLQNETQTKNSVMLWWKAPG 589
Query: 479 AESFQMHI 486
Q+++
Sbjct: 590 DPHSQLYV 597
Score = 64.7 bits (156), Expect = 2e-10
Identities = 117/519 (22%), Positives = 193/519 (37%), Gaps = 74/519 (14%)
Query: 45 DPSVATVA---TGENGITQISSTAESFHKQNGTGTPQVETNTSEDGESSGANDSLRTPEQ 101
DP +T TG+ G T+ +T ++ +G G + T S E G N S+
Sbjct: 235 DPQNSTYCVQCTGDGGRTETRNTTDTRVTVDGLGPGSLYT-CSVWVEKDGVNSSVEI--- 290
Query: 102 GSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYK-YVVKHKMENE 160
S+T P+PV ++ + + +++ LTW+ D + Y V++ +
Sbjct: 291 -----------VTSATAPNPVRNLTVEAQTNSSIALTWEVPDGPDPQNSTYGVEYTGDGG 339
Query: 161 K--TITVVHQPWCNIT--GLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVA 216
+ T + H NIT L P YVFS+ G N T P PV +L +
Sbjct: 340 RAGTRSTAHT---NITVDRLEPGCLYVFSVWVG-KNGINSSRETRNATTAPNPVRNLHME 395
Query: 217 LTGVRKAALSWSNGNGTA----SCRVLLESIGSHEELTQDSRLQVNISGLKPGVQYNINP 272
AL W +G + V G E + V L+PG Y +
Sbjct: 396 TQTNSSIALCWEVPDGPYPQDYTYWVEYTGDGGGTETRNTTNTSVTAERLEPGTLYTFSV 455
Query: 273 YLLQSNKTKGD----PLGTEGGLDASNTERSRAGS--------PTAPVHDESLV------ 314
+ + N +G + T S +++ S P P
Sbjct: 456 WA-EKNGARGSRQNVSISTVPNAVTSLSKQDWTNSTIALRWTAPQGPGQSSYSYWVSWVR 514
Query: 315 -GPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVT 373
G DP + Q + T++ L LE G+ Y+ TV+++ N G + T +V D+
Sbjct: 515 EGMTDPRT-QSTSGTDITLKELEAGSLYHLTVWAER-NEVRGYNSTLTAATAPNEVTDLQ 572
Query: 374 AVNISATSLTLIWKVSDNESSSNYTYKIHVA-------GETDSSN-----LNVSEPRAVI 421
+ S+ L WK + S Y Y + A G+ +N +E +
Sbjct: 573 NETQTKNSVMLWWKAPGDPHSQLYVYWVQWASKGHPRRGQDPQANWVNQTSRTNETWYKV 632
Query: 422 PGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTE---IGLAWSSHD 478
L T YN TV D+ + L T P V+ + VST+ + L WS
Sbjct: 633 EALEPGTLYNFTVWAERNDVASSTQSLCASTYPDTVT--ITSCVSTSAGYGVNLIWSCPQ 690
Query: 479 A--ESFQMHITQEGAGNSRVEITTNQSIIIGGLFPGTKY 515
E+F++ + G S+ + +++ + GL P Y
Sbjct: 691 GGYEAFELEV--GGQRGSQDRSSCGEAVSVLGLGPARSY 727
Score = 43.9 bits (102), Expect = 4e-04
Identities = 82/388 (21%), Positives = 152/388 (39%), Gaps = 44/388 (11%)
Query: 102 GSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTA-ASEYKYVVKHKMENE 160
G NG + + + ++T P+PV ++ + + +++ L W+ D +Y Y V++ +
Sbjct: 369 GKNGINSSRETRNATTAPNPVRNLHMETQTNSSIALCWEVPDGPYPQDYTYWVEYTGDGG 428
Query: 161 KTITVVHQPWCNITG--LRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALT 218
T T + ++T L P T Y FS+ N G + + + T P V+ L
Sbjct: 429 GTETR-NTTNTSVTAERLEPGTLYTFSVWAE-KNGARGSRQNVSISTVPNAVTSLSKQDW 486
Query: 219 GVRKAALSWS--NGNGTASCRVLLESI--GSHEELTQD-SRLQVNISGLKPGVQYNINPY 273
AL W+ G G +S + + G + TQ S + + L+ G Y++ +
Sbjct: 487 TNSTIALRWTAPQGPGQSSYSYWVSWVREGMTDPRTQSTSGTDITLKELEAGSLYHLTVW 546
Query: 274 LLQS-----NKTKGDPLGTEGGLDASNTERSRAG------SPTAPVHDESLVGPVD---- 318
++ N T D N +++ +P P H + V V
Sbjct: 547 AERNEVRGYNSTLTAATAPNEVTDLQNETQTKNSVMLWWKAPGDP-HSQLYVYWVQWASK 605
Query: 319 --PSSGQ-----------QSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTN 365
P GQ ++ +T + LEPGT YN TV+++ N Q++ T
Sbjct: 606 GHPRRGQDPQANWVNQTSRTNETWYKVEALEPGTLYNFTVWAE-RNDVASSTQSLCASTY 664
Query: 366 AIQVFDVTAVNISA-TSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAVIPGL 424
V + V+ SA + LIW + +++ V G+ S + + + GL
Sbjct: 665 PDTVTITSCVSTSAGYGVNLIWSCPQGGYEA---FELEVGGQRGSQDRSSCGEAVSVLGL 721
Query: 425 RSSTFYNITVCPVLGDIEGTPGFLQVHT 452
+ Y T+ + ++ + HT
Sbjct: 722 GPARSYPATITTIWDGMKVVSHSVVCHT 749
>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
Length = 2355
Score = 69.7 bits (169), Expect = 6e-12
Identities = 88/385 (22%), Positives = 150/385 (38%), Gaps = 53/385 (13%)
Query: 173 ITGLRPATSYVFSITPGIGNETWGDPRVI--KVITEPIPVSDLRVALTGVRKAALSWSNG 230
+T L P T YV SI G E P +I + +P DL V +SW
Sbjct: 1415 LTNLTPGTEYVVSIVALNGREE--SPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAP 1471
Query: 231 NGTASC-RVLLESIGSHEELTQ----DSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPL 285
T R+ G + + + S+ ISGLKPGV Y I Y + +GD
Sbjct: 1472 AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG---RGDSP 1528
Query: 286 GTEGGLDAS-NTERSRAGS-PTAPVHDESLVGPVDPSSGQQSR----------------- 326
+ + + TE + V D S+ PSS +
Sbjct: 1529 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588
Query: 327 -----DTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATS 381
TE+ + GL+P Y +VY+Q +G E QP TN + + ++ S
Sbjct: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG-ESQPLVQTAVTNIDRPKGLAFTDVDVDS 1647
Query: 382 LTLIWKVSDNESSSNYTYKIHVAGETDSSN-----LNVSEPRAVIPGLRSSTFYNITVCP 436
+ + W+ + S Y++ + D + + E A + GLR + Y ++V
Sbjct: 1648 IKIAWESPQGQVS---RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA 1704
Query: 437 VLGDIEGTPGFLQVHTPPVPV-SDFRVTVVSTTEIGLAWSSHDAE--SFQMHITQEGAGN 493
+ D+E P + + +P +D + T V+ T + W+ + + +++ +T +
Sbjct: 1705 LHDDMESQP-LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG 1763
Query: 494 SRVEIT---TNQSIIIGGLFPGTKY 515
EI + S+++ GL TKY
Sbjct: 1764 PMKEINLAPDSSSVVVSGLMVATKY 1788
Score = 61.2 bits (147), Expect = 2e-09
Identities = 71/306 (23%), Positives = 130/306 (42%), Gaps = 33/306 (10%)
Query: 244 GSHEELT-QDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEG---GLDASNTERS 299
GS EL ++ V +S L+PGVQYNI Y ++ N+ + P+ + G S+T S
Sbjct: 851 GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQ-ESTPVVIQQETTGTPRSDTVPS 909
Query: 300 RAGSPTAPVHDESL-----------------VGPVD--PSSGQQ---SRDTEVLLVGLEP 337
V D + V PV+ GQ+ SR+T + GL P
Sbjct: 910 PRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSP 969
Query: 338 GTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSS-N 396
G Y V++ ++G E +P + T ++ VN + +++ + W + +
Sbjct: 970 GVTYYFKVFA-VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYR 1028
Query: 397 YTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEG--TPGFLQVHTPP 454
T + G+ N+ S + + L+ ++ Y +++ + G+ E G P
Sbjct: 1029 LTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG 1088
Query: 455 VPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVEITTNQ-SIIIGGLFPGT 513
+ + V TT I + W+ F++ + G + E+T++ SI++ GL PG
Sbjct: 1089 SSIPPYNTEVTETT-IVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGV 1147
Query: 514 KYCFEI 519
+Y + I
Sbjct: 1148 EYVYTI 1153
Score = 58.5 bits (140), Expect = 1e-08
Identities = 100/467 (21%), Positives = 163/467 (34%), Gaps = 53/467 (11%)
Query: 110 SQKTPSSTG------PSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTI 163
+Q++P +TG P ++ T +++TW +K V+ E
Sbjct: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG--FKLGVRPSQGGEAPR 1129
Query: 164 TVVHQPWCNI-TGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVAL---TG 219
V + +GL P YV++I + P V KV+T P ++L + TG
Sbjct: 1130 EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTG 1189
Query: 220 VRKAALSWSNGNGTASCRVLL-----ESIGSHEELTQDSRLQVNISGLKPGVQYNINPYL 274
V + S R+ + S EE+ + L PG++YN++ Y
Sbjct: 1190 VLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
Query: 275 LQSNKTK--------------GDPLGTEGGLDASNTERSRAGS--------PTAPVHDES 312
++ +K D T G D + S +PV +E
Sbjct: 1250 VKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1309
Query: 313 LVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDV 372
V + S D V+L L PGT Y +V S E P +T +
Sbjct: 1310 DVAELSISPS----DNAVVLTNLLPGTEYVVSV-SSVYEQHESTPLRGRQKTGLDSPTGI 1364
Query: 373 TAVNISATSLTLIWKVSDNESSSNYT---YKIHVAGETDSSNLNVSEPRAVIPGLRSSTF 429
+I+A S T+ W ++ + + Y + H +G + S + L T
Sbjct: 1365 DFSDITANSFTVHW-IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
Query: 430 YNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQ- 488
Y +++ + G E Q T D V + T + ++W + IT
Sbjct: 1424 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG 1483
Query: 489 EGAGNSRVEITT----NQSIIIGGLFPGTKYCFEIVPKGPNGTEGAS 531
E GNS V+ T + I GL PG Y + G AS
Sbjct: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
Score = 54.3 bits (129), Expect = 3e-07
Identities = 94/435 (21%), Positives = 163/435 (37%), Gaps = 51/435 (11%)
Query: 124 DIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENE--KTITVV-HQPWCNITGLRPAT 180
D++ V+ +PT+++++W + Y+ N + TV + I+GL+P
Sbjct: 1453 DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGV 1512
Query: 181 SY---VFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSW--SNGNGTAS 235
Y V+++T + P I TE S ++V ++ W S+ T
Sbjct: 1513 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGY 1572
Query: 236 CRVLLESIGSHEELTQDS---RLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLD 292
G T+ + + ++ I GL+P V+Y ++ Y Q+ + PL
Sbjct: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY-AQNPSGESQPLVQTA--- 1628
Query: 293 ASNTERSRAGSPTAPVHDESLVGPVDPSSGQQSR----------------------DTEV 330
+N +R + G V +S+ + GQ SR +
Sbjct: 1629 VTNIDRPK-GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1687
Query: 331 LLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSD 390
L GL PG+ Y +V + + E QP T D+ ++ TSL+ W
Sbjct: 1688 ELQGLRPGSEYTVSVVA-LHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQW-TPP 1745
Query: 391 NESSSNYTYKI---HVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTP-- 445
N + Y ++ G NL V+ GL +T Y ++V + + P
Sbjct: 1746 NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ 1805
Query: 446 GFLQVHTPPVPVSDFRVTVVSTTEIGLAW--SSHDAESFQMHITQEGAGNSRVEITTN-- 501
G + P RVT + T I ++W + FQ+ G + ++ T
Sbjct: 1806 GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPD 1864
Query: 502 -QSIIIGGLFPGTKY 515
+S I GL PGT Y
Sbjct: 1865 VRSYTITGLQPGTDY 1879
Score = 51.2 bits (121), Expect = 2e-06
Identities = 87/383 (22%), Positives = 143/383 (37%), Gaps = 41/383 (10%)
Query: 173 ITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAAL--SWSNG 230
+ L+PA+ Y S+ GN+ P+ V T P S + T V + + +W+
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
Query: 231 NGTASCRVLLESIGSH--EELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDP---- 284
+ S G E+T DS + +SGL PGV+Y +L+ + + P
Sbjct: 1111 PRIGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNK 1169
Query: 285 ----------LGTEGGLDASNTERSRAGSPTAPVHDESLVGPVDPSSGQQSRDTEVLL-- 332
L E D S S T + + P++GQQ E ++
Sbjct: 1170 VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRIT--TTPTNGQQGNSLEEVVHA 1227
Query: 333 -------VGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLI 385
L PG YN +VY+ + E P + D+ NI ++ +
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYT-VKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVT 1286
Query: 386 WKVSDNESSSNYTYKIH-VAGETDSSNLNV--SEPRAVIPGLRSSTFYNITVCPVLGDIE 442
W + +N+ + V E D + L++ S+ V+ L T Y ++V V E
Sbjct: 1287 WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
Query: 443 GTPGFLQVHT---PPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVEIT 499
TP + T P + +T S T +A + H + +G R +
Sbjct: 1347 STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
Query: 500 --TNQSIIIGGLFPGTKYCFEIV 520
+ SI + L PGT+Y IV
Sbjct: 1407 PHSRNSITLTNLTPGTEYVVSIV 1429
Score = 49.7 bits (117), Expect = 7e-06
Identities = 47/208 (22%), Positives = 79/208 (37%), Gaps = 13/208 (6%)
Query: 325 SRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTL 384
S T V + L PG +Y VY + +G + + T D T + TS+ +
Sbjct: 770 STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVV 829
Query: 385 IWKVSDNESSS-NYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEG 443
W + Y V G + NL + + L+ YNIT+ V + E
Sbjct: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
Query: 444 TPGFLQVHTPPVPVS-------DFRVTVVSTTEIGLAWSSHDA-----ESFQMHITQEGA 491
TP +Q T P S D + V+ ++ + W+ ++ + + G
Sbjct: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
Query: 492 GNSRVEITTNQSIIIGGLFPGTKYCFEI 519
R+ I+ N + GL PG Y F++
Sbjct: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKV 977
Score = 47.8 bits (112), Expect = 3e-05
Identities = 106/530 (20%), Positives = 185/530 (34%), Gaps = 65/530 (12%)
Query: 44 PDPSVATVATGEN---GITQISSTAESFHKQNGTGTPQV----ETNTSEDGESSGA--ND 94
PD V TV+ + IT T + Q G +V +++ + D S G N
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
Query: 95 SLRTPEQGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVK 154
S+ T + + P+ P+ D++ +I P + +TW + V
Sbjct: 1246 SVYTVKDDKESVPISDTIIPAVPPPT---DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRY 1302
Query: 155 HKMENEKTITVVH-QPWCN---ITGLRPATSYVFSI---------TPGIGNETWGDPRVI 201
++NE+ + + P N +T L P T YV S+ TP G + G
Sbjct: 1303 SPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
Query: 202 KVITEPIPVSDLRVALTGVRKAALSWSNGNGTASCRVLLESIGSHEELTQDSRLQVNISG 261
+ I + V R + + S E+ SR + ++
Sbjct: 1363 GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHF-----SGRPREDRVPHSRNSITLTN 1417
Query: 262 LKPGVQYNINPYLLQSNKTKGDPLGTEGGL-DASNTERSRAGSPTAPV--HDESLV---- 314
L PG +Y ++ L + +G + + D A +PT+ + D V
Sbjct: 1418 LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY 1477
Query: 315 -----------GPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANG---TEGQPQAI 360
PV + S+ T + GL+PG Y TVY+ G +P +I
Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATIS-GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
Query: 361 EFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVA-----GETDSSNLNVS 415
+RT + + ++ S+++ W S SS Y++ G T +
Sbjct: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLPS---SSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
Query: 416 EPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWS 475
+ I GL+ + Y ++V E P T T V I +AW
Sbjct: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWE 1653
Query: 476 SHDAESFQMHITQEGAGNSRVEI-----TTNQSIIIGGLFPGTKYCFEIV 520
S + + +T + E+ + + GL PG++Y +V
Sbjct: 1654 SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1703
Score = 42.7 bits (99), Expect = 8e-04
Identities = 77/437 (17%), Positives = 153/437 (35%), Gaps = 34/437 (7%)
Query: 115 SSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKY---VVKHKMENEKTITVVHQPWC 171
S T PSP D++ V ++ V + W ++A + Y+ V E+ + + + +
Sbjct: 904 SDTVPSPR-DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFA 962
Query: 172 NITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGN 231
+TGL P +Y F + + + P + T+ ++L+ + W+
Sbjct: 963 EVTGLSPGVTYYFKVF-AVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
Query: 232 GTASCRVLLESIGSHEELTQ----DSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGT 287
+ L + + Q S + + L+P +Y ++ ++ N+ G
Sbjct: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
Query: 288 ------EGGLDASNTE--RSRAGSPTAPVHDESLVGPVDPSSGQQ------SRDTEVLLV 333
+ NTE + P V PS G + S +++
Sbjct: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVS 1141
Query: 334 GLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDV-TAVNISATSLTLIWKVSDNE 392
GL PG Y T+ P + T ++ N LT+ W+ S
Sbjct: 1142 GLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP 1201
Query: 393 SSSNYTYKIHVAGETDSSNL----NVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFL 448
+ Y ++L + + L YN++V V D E P
Sbjct: 1202 DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD 1261
Query: 449 QVHTPPVPVSDFRVTVVSTTEIGLAWS---SHDAESFQMHITQEGAGNSRVEIT---TNQ 502
+ P +D R T + + + W+ S D +F + + E++ ++
Sbjct: 1262 TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDN 1321
Query: 503 SIIIGGLFPGTKYCFEI 519
++++ L PGT+Y +
Sbjct: 1322 AVVLTNLLPGTEYVVSV 1338
Score = 41.6 bits (96), Expect = 0.002
Identities = 80/339 (23%), Positives = 125/339 (36%), Gaps = 77/339 (22%)
Query: 111 QKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENE----KTITVV 166
Q PSS+GP VF + S P + + W + + KY+++ + +N K T+
Sbjct: 603 QTYPSSSGPVEVFITETPS-QPNSHPIQWNAPQPSHIS-KYILRWRPKNSVGRWKEATIP 660
Query: 167 -HQPWCNITGLRPATSYVFSITPGIGNETWGDPRVIK----------------VITEPIP 209
H I GL+P Y + I + +G V + V E P
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQL---ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
Query: 210 VSDLRVALTGVRKAA-----LSWSNGNGTAS-CRVLLESIGSHEELTQ----DSRLQVNI 259
S L V + +SW + + T S RV E +E + VNI
Sbjct: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNI 777
Query: 260 SGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAP----VHDESLV- 314
L PG +Y +N Y + + E L S ++ + +P P V D S+V
Sbjct: 778 PDLLPGRKYIVNVYQISED--------GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVV 829
Query: 315 ---GPVDPSSGQ--------QSRDTE---------VLLVGLEPGTRYNATVYSQAANGTE 354
P P +G + TE V L L+PG +YN T+Y+ N E
Sbjct: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN-QE 888
Query: 355 GQPQAIEFRTNAI-------QVFDVTAVNISATSLTLIW 386
P I+ T D+ V ++ +T++W
Sbjct: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW 927
Score = 38.1 bits (87), Expect = 0.021
Identities = 74/353 (20%), Positives = 125/353 (35%), Gaps = 34/353 (9%)
Query: 134 NVILTWKSNDTAASEYKYVVKHKMENEKTITVV---HQPWCNITGLRPATSYVFSITPGI 190
++ + W+S S Y+ + + + + GLRP + Y S+ +
Sbjct: 1647 SIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV-AL 1705
Query: 191 GNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGN-GTASCRVLL---ESIGSH 246
++ P + T +DL+ + W+ N RV + E G
Sbjct: 1706 HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1765
Query: 247 EE--LTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLD-ASNTERSRAGS 303
+E L DS V +SGL +Y ++ Y L+ T G L+ S R+R
Sbjct: 1766 KEINLAPDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTD 1824
Query: 304 PTAPV-------HDESLVG-PVD--PSSGQQSRDTEV-------LLVGLEPGTRYNATVY 346
T E++ G VD P++GQ + + GL+PGT Y +Y
Sbjct: 1825 ATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1884
Query: 347 SQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGE 406
+ N P I+ T ++ + + SL + W+ + Y K G
Sbjct: 1885 TLNDN-ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQ-PPRARITGYIIKYEKPGS 1942
Query: 407 TDSSNLNVSEP---RAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVP 456
+ P A I GL T Y I V + + + P + T +P
Sbjct: 1943 PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 1995
Score = 33.1 bits (74), Expect = 0.66
Identities = 70/308 (22%), Positives = 108/308 (35%), Gaps = 41/308 (13%)
Query: 110 SQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQP 169
SQ T P P D + T++++ W + Y+ V +E T + +
Sbjct: 806 SQTTAPDAPPDPTVD----QVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPET 861
Query: 170 WCNIT--GLRPATSYVFSI---------TP-GIGNETWGDPRVIKVITEPIPVSDLRVAL 217
++T L+P Y +I TP I ET G PR T P P V +
Sbjct: 862 ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPR---SDTVPSPRDLQFVEV 918
Query: 218 TGVRKAALSWSNGNGTASCRVLLESI---GSHEELTQDSR-LQVNISGLKPGVQYNINPY 273
T V+ + + RV + + G H + SR ++GL PGV Y +
Sbjct: 919 TDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVF 978
Query: 274 ----------LLQSNKTKGD-PLGTEGGLDASNTERSRAGSPTAPVHDESL-VGPVDPSS 321
L TK D P + + +T R P A + L VG
Sbjct: 979 AVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
Query: 322 GQQ----SRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNI 377
+Q ++ L L+P + Y TV A G + P+A T + N
Sbjct: 1039 PRQYNVGPSVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
Query: 378 SATSLTLI 385
T T++
Sbjct: 1097 EVTETTIV 1104
>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
Length = 2477
Score = 69.7 bits (169), Expect = 6e-12
Identities = 88/385 (22%), Positives = 150/385 (38%), Gaps = 53/385 (13%)
Query: 173 ITGLRPATSYVFSITPGIGNETWGDPRVI--KVITEPIPVSDLRVALTGVRKAALSWSNG 230
+T L P T YV SI G E P +I + +P DL V +SW
Sbjct: 1506 LTNLTPGTEYVVSIVALNGREE--SPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAP 1562
Query: 231 NGTASC-RVLLESIGSHEELTQ----DSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPL 285
T R+ G + + + S+ ISGLKPGV Y I Y + +GD
Sbjct: 1563 AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG---RGDSP 1619
Query: 286 GTEGGLDAS-NTERSRAGS-PTAPVHDESLVGPVDPSSGQQSR----------------- 326
+ + + TE + V D S+ PSS +
Sbjct: 1620 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1679
Query: 327 -----DTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATS 381
TE+ + GL+P Y +VY+Q +G E QP TN + + ++ S
Sbjct: 1680 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG-ESQPLVQTAVTNIDRPKGLAFTDVDVDS 1738
Query: 382 LTLIWKVSDNESSSNYTYKIHVAGETDSSN-----LNVSEPRAVIPGLRSSTFYNITVCP 436
+ + W+ + S Y++ + D + + E A + GLR + Y ++V
Sbjct: 1739 IKIAWESPQGQVS---RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA 1795
Query: 437 VLGDIEGTPGFLQVHTPPVPV-SDFRVTVVSTTEIGLAWSSHDAE--SFQMHITQEGAGN 493
+ D+E P + + +P +D + T V+ T + W+ + + +++ +T +
Sbjct: 1796 LHDDMESQP-LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG 1854
Query: 494 SRVEIT---TNQSIIIGGLFPGTKY 515
EI + S+++ GL TKY
Sbjct: 1855 PMKEINLAPDSSSVVVSGLMVATKY 1879
Score = 68.2 bits (165), Expect = 2e-11
Identities = 85/383 (22%), Positives = 151/383 (39%), Gaps = 42/383 (10%)
Query: 173 ITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAAL--SWSNG 230
+ L+PA+ Y S+ GN+ P+ V T P S + T V + + +W+
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
Query: 231 NGTASCRVLLESIGSH--EELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDP---- 284
+ S G E+T DS + +SGL PGV+Y +L+ + + P
Sbjct: 1111 PRIGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNK 1169
Query: 285 ----------LGTEGGLDASNTERSRAGSPTAPVHDESLVGPVDPSSGQQSRDTEVLLVG 334
L E D S S T + + P++GQQ E ++
Sbjct: 1170 VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRIT--TTPTNGQQGNSLEEVVHA 1227
Query: 335 ---------LEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLI 385
L PG YN +VY+ + E P + Q+ D++ V+I+ +S+ L
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYT-VKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLR 1286
Query: 386 WKVSDNESSSNYTYKIHVAGE---TDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIE 442
W ++ + Y + AGE ++ S + GL Y+I+V ++ E
Sbjct: 1287 WTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGE 1346
Query: 443 GTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWS---SHDAESFQMHITQEGAGNSRVEIT 499
P L T P +D R T + + + W+ S D +F + + E++
Sbjct: 1347 SAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1406
Query: 500 ---TNQSIIIGGLFPGTKYCFEI 519
++ ++++ L PGT+Y +
Sbjct: 1407 ISPSDNAVVLTNLLPGTEYVVSV 1429
Score = 61.2 bits (147), Expect = 2e-09
Identities = 74/306 (24%), Positives = 133/306 (43%), Gaps = 33/306 (10%)
Query: 244 GSHEELT-QDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTE---GGLDASNTERS 299
GS EL ++ V +S L+PGVQYNI Y ++ N+ + P+ + G S+T S
Sbjct: 851 GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQ-ESTPVVIQQETTGTPRSDTVPS 909
Query: 300 RAGSPTAPVHDESL-----------------VGPVD--PSSGQQ---SRDTEVLLVGLEP 337
V D + V PV+ GQ+ SR+T + GL P
Sbjct: 910 PRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSP 969
Query: 338 GTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNE-SSSN 396
G Y V++ ++G E +P + T ++ VN + +++ + W + +
Sbjct: 970 GVTYYFKVFA-VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYR 1028
Query: 397 YTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVP 456
T + G+ N+ S + + L+ ++ Y +++ + G+ E +P V T P
Sbjct: 1029 LTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE-SPKATGVFTTLQP 1087
Query: 457 VSDFRV--TVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVEITTNQ-SIIIGGLFPGT 513
S T V+ T I + W+ F++ + G + E+T++ SI++ GL PG
Sbjct: 1088 GSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGV 1147
Query: 514 KYCFEI 519
+Y + I
Sbjct: 1148 EYVYTI 1153
Score = 54.3 bits (129), Expect = 3e-07
Identities = 94/435 (21%), Positives = 163/435 (37%), Gaps = 51/435 (11%)
Query: 124 DIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENE--KTITVV-HQPWCNITGLRPAT 180
D++ V+ +PT+++++W + Y+ N + TV + I+GL+P
Sbjct: 1544 DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGV 1603
Query: 181 SY---VFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSW--SNGNGTAS 235
Y V+++T + P I TE S ++V ++ W S+ T
Sbjct: 1604 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGY 1663
Query: 236 CRVLLESIGSHEELTQDS---RLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLD 292
G T+ + + ++ I GL+P V+Y ++ Y Q+ + PL
Sbjct: 1664 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY-AQNPSGESQPLVQTA--- 1719
Query: 293 ASNTERSRAGSPTAPVHDESLVGPVDPSSGQQSR----------------------DTEV 330
+N +R + G V +S+ + GQ SR +
Sbjct: 1720 VTNIDRPK-GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778
Query: 331 LLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSD 390
L GL PG+ Y +V + + E QP T D+ ++ TSL+ W
Sbjct: 1779 ELQGLRPGSEYTVSVVA-LHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQW-TPP 1836
Query: 391 NESSSNYTYKI---HVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTP-- 445
N + Y ++ G NL V+ GL +T Y ++V + + P
Sbjct: 1837 NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ 1896
Query: 446 GFLQVHTPPVPVSDFRVTVVSTTEIGLAW--SSHDAESFQMHITQEGAGNSRVEITTN-- 501
G + P RVT + T I ++W + FQ+ G + ++ T
Sbjct: 1897 GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPD 1955
Query: 502 -QSIIIGGLFPGTKY 515
+S I GL PGT Y
Sbjct: 1956 VRSYTITGLQPGTDY 1970
Score = 51.6 bits (122), Expect = 2e-06
Identities = 92/461 (19%), Positives = 159/461 (34%), Gaps = 53/461 (11%)
Query: 104 NGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTI 163
NG + A T P D++ +I P + +TW + V ++NE+ +
Sbjct: 1343 NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDV 1402
Query: 164 TVVH-QPWCN---ITGLRPATSYVFSI---------TPGIGNETWGDPRVIKVITEPIPV 210
+ P N +T L P T YV S+ TP G + G + I
Sbjct: 1403 AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITA 1462
Query: 211 SDLRVALTGVRKAALSWSNGNGTASCRVLLESIGSHEELTQDSRLQVNISGLKPGVQYNI 270
+ V R + + S E+ SR + ++ L PG +Y +
Sbjct: 1463 NSFTVHWIAPRATITGYRIRHHPEHF-----SGRPREDRVPHSRNSITLTNLTPGTEYVV 1517
Query: 271 NPYLLQSNKTKGDPLGTEGGL-DASNTERSRAGSPTAPV--HDESLV------------- 314
+ L + +G + + D A +PT+ + D V
Sbjct: 1518 SIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1577
Query: 315 --GPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANG---TEGQPQAIEFRTNAIQV 369
PV + S+ T + GL+PG Y TVY+ G +P +I +RT +
Sbjct: 1578 GNSPVQEFTVPGSKSTATIS-GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP 1636
Query: 370 FDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVA-----GETDSSNLNVSEPRAVIPGL 424
+ ++ S+++ W S SS Y++ G T + + I GL
Sbjct: 1637 SQMQVTDVQDNSISVKWLPS---SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1693
Query: 425 RSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQM 484
+ + Y ++V E P T T V I +AW S + +
Sbjct: 1694 QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRY 1753
Query: 485 HITQEGAGNSRVEI-----TTNQSIIIGGLFPGTKYCFEIV 520
+T + E+ + + GL PG++Y +V
Sbjct: 1754 RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1794
Score = 49.7 bits (117), Expect = 7e-06
Identities = 47/208 (22%), Positives = 79/208 (37%), Gaps = 13/208 (6%)
Query: 325 SRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTL 384
S T V + L PG +Y VY + +G + + T D T + TS+ +
Sbjct: 770 STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVV 829
Query: 385 IWKVSDNESSS-NYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEG 443
W + Y V G + NL + + L+ YNIT+ V + E
Sbjct: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
Query: 444 TPGFLQVHTPPVPVS-------DFRVTVVSTTEIGLAWSSHDA-----ESFQMHITQEGA 491
TP +Q T P S D + V+ ++ + W+ ++ + + G
Sbjct: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
Query: 492 GNSRVEITTNQSIIIGGLFPGTKYCFEI 519
R+ I+ N + GL PG Y F++
Sbjct: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKV 977
Score = 47.0 bits (110), Expect = 4e-05
Identities = 86/457 (18%), Positives = 163/457 (35%), Gaps = 37/457 (8%)
Query: 115 SSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKY---VVKHKMENEKTITVVHQPWC 171
S T PSP D++ V ++ V + W ++A + Y+ V E+ + + + +
Sbjct: 904 SDTVPSPR-DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFA 962
Query: 172 NITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGN 231
+TGL P +Y F + + + P + T+ ++L+ + W+
Sbjct: 963 EVTGLSPGVTYYFKVF-AVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
Query: 232 GTASCRVLLESIGSHEELTQ----DSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGT 287
+ L + + Q S + + L+P +Y ++ ++ N+ G
Sbjct: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
Query: 288 ------EGGLDASNTE--RSRAGSPTAPVHDESLVGPVDPSSGQQ------SRDTEVLLV 333
+ NTE + P V PS G + S +++
Sbjct: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVS 1141
Query: 334 GLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDV-TAVNISATSLTLIWKVSDNE 392
GL PG Y T+ P + T ++ N LT+ W+ S
Sbjct: 1142 GLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP 1201
Query: 393 SSSNYTYKIHVAGETDSSNL----NVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFL 448
+ Y ++L + + L YN++V V D E P
Sbjct: 1202 DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP-IS 1260
Query: 449 QVHTPPVP-VSDFRVTVVSTTEIGLAWSSHDAES---FQMHITQEGAGNSRVEITTNQSI 504
P VP ++D ++ + IGL W+ ++ + +++ + G G E + S+
Sbjct: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
Query: 505 ---IIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRT 538
+ GL PG Y ++ NG E A T+ +T
Sbjct: 1321 GYYTVTGLEPGIDYDISVITL-INGGESAPTTLTQQT 1356
Score = 41.6 bits (96), Expect = 0.002
Identities = 80/339 (23%), Positives = 125/339 (36%), Gaps = 77/339 (22%)
Query: 111 QKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENE----KTITVV 166
Q PSS+GP VF + S P + + W + + KY+++ + +N K T+
Sbjct: 603 QTYPSSSGPVEVFITETPS-QPNSHPIQWNAPQPSHIS-KYILRWRPKNSVGRWKEATIP 660
Query: 167 -HQPWCNITGLRPATSYVFSITPGIGNETWGDPRVIK----------------VITEPIP 209
H I GL+P Y + I + +G V + V E P
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQL---ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
Query: 210 VSDLRVALTGVRKAA-----LSWSNGNGTAS-CRVLLESIGSHEELTQ----DSRLQVNI 259
S L V + +SW + + T S RV E +E + VNI
Sbjct: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNI 777
Query: 260 SGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAP----VHDESLV- 314
L PG +Y +N Y + + E L S ++ + +P P V D S+V
Sbjct: 778 PDLLPGRKYIVNVYQISED--------GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVV 829
Query: 315 ---GPVDPSSGQ--------QSRDTE---------VLLVGLEPGTRYNATVYSQAANGTE 354
P P +G + TE V L L+PG +YN T+Y+ N E
Sbjct: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN-QE 888
Query: 355 GQPQAIEFRTNAI-------QVFDVTAVNISATSLTLIW 386
P I+ T D+ V ++ +T++W
Sbjct: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW 927
Score = 38.1 bits (87), Expect = 0.021
Identities = 74/353 (20%), Positives = 125/353 (35%), Gaps = 34/353 (9%)
Query: 134 NVILTWKSNDTAASEYKYVVKHKMENEKTITVV---HQPWCNITGLRPATSYVFSITPGI 190
++ + W+S S Y+ + + + + GLRP + Y S+ +
Sbjct: 1738 SIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV-AL 1796
Query: 191 GNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGN-GTASCRVLL---ESIGSH 246
++ P + T +DL+ + W+ N RV + E G
Sbjct: 1797 HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1856
Query: 247 EE--LTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLD-ASNTERSRAGS 303
+E L DS V +SGL +Y ++ Y L+ T G L+ S R+R
Sbjct: 1857 KEINLAPDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTD 1915
Query: 304 PTAPV-------HDESLVG-PVD--PSSGQQSRDTEV-------LLVGLEPGTRYNATVY 346
T E++ G VD P++GQ + + GL+PGT Y +Y
Sbjct: 1916 ATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1975
Query: 347 SQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGE 406
+ N P I+ T ++ + + SL + W+ + Y K G
Sbjct: 1976 TLNDN-ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQ-PPRARITGYIIKYEKPGS 2033
Query: 407 TDSSNLNVSEP---RAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVP 456
+ P A I GL T Y I V + + + P + T +P
Sbjct: 2034 PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 2086
Score = 33.1 bits (74), Expect = 0.66
Identities = 70/308 (22%), Positives = 108/308 (35%), Gaps = 41/308 (13%)
Query: 110 SQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQP 169
SQ T P P D + T++++ W + Y+ V +E T + +
Sbjct: 806 SQTTAPDAPPDPTVD----QVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPET 861
Query: 170 WCNIT--GLRPATSYVFSI---------TP-GIGNETWGDPRVIKVITEPIPVSDLRVAL 217
++T L+P Y +I TP I ET G PR T P P V +
Sbjct: 862 ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPR---SDTVPSPRDLQFVEV 918
Query: 218 TGVRKAALSWSNGNGTASCRVLLESI---GSHEELTQDSR-LQVNISGLKPGVQYNINPY 273
T V+ + + RV + + G H + SR ++GL PGV Y +
Sbjct: 919 TDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVF 978
Query: 274 ----------LLQSNKTKGD-PLGTEGGLDASNTERSRAGSPTAPVHDESL-VGPVDPSS 321
L TK D P + + +T R P A + L VG
Sbjct: 979 AVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
Query: 322 GQQ----SRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNI 377
+Q ++ L L+P + Y TV A G + P+A T + N
Sbjct: 1039 PRQYNVGPSVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
Query: 378 SATSLTLI 385
T T++
Sbjct: 1097 EVTETTIV 1104
>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
Length = 2330
Score = 69.7 bits (169), Expect = 6e-12
Identities = 88/385 (22%), Positives = 150/385 (38%), Gaps = 53/385 (13%)
Query: 173 ITGLRPATSYVFSITPGIGNETWGDPRVI--KVITEPIPVSDLRVALTGVRKAALSWSNG 230
+T L P T YV SI G E P +I + +P DL V +SW
Sbjct: 1415 LTNLTPGTEYVVSIVALNGREE--SPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAP 1471
Query: 231 NGTASC-RVLLESIGSHEELTQ----DSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPL 285
T R+ G + + + S+ ISGLKPGV Y I Y + +GD
Sbjct: 1472 AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG---RGDSP 1528
Query: 286 GTEGGLDAS-NTERSRAGS-PTAPVHDESLVGPVDPSSGQQSR----------------- 326
+ + + TE + V D S+ PSS +
Sbjct: 1529 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588
Query: 327 -----DTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATS 381
TE+ + GL+P Y +VY+Q +G E QP TN + + ++ S
Sbjct: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG-ESQPLVQTAVTNIDRPKGLAFTDVDVDS 1647
Query: 382 LTLIWKVSDNESSSNYTYKIHVAGETDSSN-----LNVSEPRAVIPGLRSSTFYNITVCP 436
+ + W+ + S Y++ + D + + E A + GLR + Y ++V
Sbjct: 1648 IKIAWESPQGQVS---RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA 1704
Query: 437 VLGDIEGTPGFLQVHTPPVPV-SDFRVTVVSTTEIGLAWSSHDAE--SFQMHITQEGAGN 493
+ D+E P + + +P +D + T V+ T + W+ + + +++ +T +
Sbjct: 1705 LHDDMESQP-LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG 1763
Query: 494 SRVEIT---TNQSIIIGGLFPGTKY 515
EI + S+++ GL TKY
Sbjct: 1764 PMKEINLAPDSSSVVVSGLMVATKY 1788
Score = 61.2 bits (147), Expect = 2e-09
Identities = 71/306 (23%), Positives = 130/306 (42%), Gaps = 33/306 (10%)
Query: 244 GSHEELT-QDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEG---GLDASNTERS 299
GS EL ++ V +S L+PGVQYNI Y ++ N+ + P+ + G S+T S
Sbjct: 851 GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQ-ESTPVVIQQETTGTPRSDTVPS 909
Query: 300 RAGSPTAPVHDESL-----------------VGPVD--PSSGQQ---SRDTEVLLVGLEP 337
V D + V PV+ GQ+ SR+T + GL P
Sbjct: 910 PRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSP 969
Query: 338 GTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSS-N 396
G Y V++ ++G E +P + T ++ VN + +++ + W + +
Sbjct: 970 GVTYYFKVFA-VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYR 1028
Query: 397 YTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEG--TPGFLQVHTPP 454
T + G+ N+ S + + L+ ++ Y +++ + G+ E G P
Sbjct: 1029 LTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG 1088
Query: 455 VPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVEITTNQ-SIIIGGLFPGT 513
+ + V TT I + W+ F++ + G + E+T++ SI++ GL PG
Sbjct: 1089 SSIPPYNTEVTETT-IVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGV 1147
Query: 514 KYCFEI 519
+Y + I
Sbjct: 1148 EYVYTI 1153
Score = 58.5 bits (140), Expect = 1e-08
Identities = 100/467 (21%), Positives = 163/467 (34%), Gaps = 53/467 (11%)
Query: 110 SQKTPSSTG------PSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTI 163
+Q++P +TG P ++ T +++TW +K V+ E
Sbjct: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG--FKLGVRPSQGGEAPR 1129
Query: 164 TVVHQPWCNI-TGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVAL---TG 219
V + +GL P YV++I + P V KV+T P ++L + TG
Sbjct: 1130 EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTG 1189
Query: 220 VRKAALSWSNGNGTASCRVLL-----ESIGSHEELTQDSRLQVNISGLKPGVQYNINPYL 274
V + S R+ + S EE+ + L PG++YN++ Y
Sbjct: 1190 VLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
Query: 275 LQSNKTK--------------GDPLGTEGGLDASNTERSRAGS--------PTAPVHDES 312
++ +K D T G D + S +PV +E
Sbjct: 1250 VKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1309
Query: 313 LVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDV 372
V + S D V+L L PGT Y +V S E P +T +
Sbjct: 1310 DVAELSISPS----DNAVVLTNLLPGTEYVVSV-SSVYEQHESTPLRGRQKTGLDSPTGI 1364
Query: 373 TAVNISATSLTLIWKVSDNESSSNYT---YKIHVAGETDSSNLNVSEPRAVIPGLRSSTF 429
+I+A S T+ W ++ + + Y + H +G + S + L T
Sbjct: 1365 DFSDITANSFTVHW-IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
Query: 430 YNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQ- 488
Y +++ + G E Q T D V + T + ++W + IT
Sbjct: 1424 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG 1483
Query: 489 EGAGNSRVEITT----NQSIIIGGLFPGTKYCFEIVPKGPNGTEGAS 531
E GNS V+ T + I GL PG Y + G AS
Sbjct: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
Score = 54.3 bits (129), Expect = 3e-07
Identities = 94/435 (21%), Positives = 163/435 (37%), Gaps = 51/435 (11%)
Query: 124 DIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENE--KTITVV-HQPWCNITGLRPAT 180
D++ V+ +PT+++++W + Y+ N + TV + I+GL+P
Sbjct: 1453 DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGV 1512
Query: 181 SY---VFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSW--SNGNGTAS 235
Y V+++T + P I TE S ++V ++ W S+ T
Sbjct: 1513 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGY 1572
Query: 236 CRVLLESIGSHEELTQDS---RLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLD 292
G T+ + + ++ I GL+P V+Y ++ Y Q+ + PL
Sbjct: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY-AQNPSGESQPLVQTA--- 1628
Query: 293 ASNTERSRAGSPTAPVHDESLVGPVDPSSGQQSR----------------------DTEV 330
+N +R + G V +S+ + GQ SR +
Sbjct: 1629 VTNIDRPK-GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1687
Query: 331 LLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSD 390
L GL PG+ Y +V + + E QP T D+ ++ TSL+ W
Sbjct: 1688 ELQGLRPGSEYTVSVVA-LHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQW-TPP 1745
Query: 391 NESSSNYTYKI---HVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTP-- 445
N + Y ++ G NL V+ GL +T Y ++V + + P
Sbjct: 1746 NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ 1805
Query: 446 GFLQVHTPPVPVSDFRVTVVSTTEIGLAW--SSHDAESFQMHITQEGAGNSRVEITTN-- 501
G + P RVT + T I ++W + FQ+ G + ++ T
Sbjct: 1806 GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPD 1864
Query: 502 -QSIIIGGLFPGTKY 515
+S I GL PGT Y
Sbjct: 1865 VRSYTITGLQPGTDY 1879
Score = 51.2 bits (121), Expect = 2e-06
Identities = 87/383 (22%), Positives = 143/383 (37%), Gaps = 41/383 (10%)
Query: 173 ITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAAL--SWSNG 230
+ L+PA+ Y S+ GN+ P+ V T P S + T V + + +W+
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
Query: 231 NGTASCRVLLESIGSH--EELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDP---- 284
+ S G E+T DS + +SGL PGV+Y +L+ + + P
Sbjct: 1111 PRIGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNK 1169
Query: 285 ----------LGTEGGLDASNTERSRAGSPTAPVHDESLVGPVDPSSGQQSRDTEVLL-- 332
L E D S S T + + P++GQQ E ++
Sbjct: 1170 VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRIT--TTPTNGQQGNSLEEVVHA 1227
Query: 333 -------VGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLI 385
L PG YN +VY+ + E P + D+ NI ++ +
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYT-VKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVT 1286
Query: 386 WKVSDNESSSNYTYKIH-VAGETDSSNLNV--SEPRAVIPGLRSSTFYNITVCPVLGDIE 442
W + +N+ + V E D + L++ S+ V+ L T Y ++V V E
Sbjct: 1287 WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
Query: 443 GTPGFLQVHT---PPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVEIT 499
TP + T P + +T S T +A + H + +G R +
Sbjct: 1347 STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
Query: 500 --TNQSIIIGGLFPGTKYCFEIV 520
+ SI + L PGT+Y IV
Sbjct: 1407 PHSRNSITLTNLTPGTEYVVSIV 1429
Score = 49.7 bits (117), Expect = 7e-06
Identities = 47/208 (22%), Positives = 79/208 (37%), Gaps = 13/208 (6%)
Query: 325 SRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTL 384
S T V + L PG +Y VY + +G + + T D T + TS+ +
Sbjct: 770 STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVV 829
Query: 385 IWKVSDNESSS-NYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEG 443
W + Y V G + NL + + L+ YNIT+ V + E
Sbjct: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
Query: 444 TPGFLQVHTPPVPVS-------DFRVTVVSTTEIGLAWSSHDA-----ESFQMHITQEGA 491
TP +Q T P S D + V+ ++ + W+ ++ + + G
Sbjct: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
Query: 492 GNSRVEITTNQSIIIGGLFPGTKYCFEI 519
R+ I+ N + GL PG Y F++
Sbjct: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKV 977
Score = 47.8 bits (112), Expect = 3e-05
Identities = 106/530 (20%), Positives = 185/530 (34%), Gaps = 65/530 (12%)
Query: 44 PDPSVATVATGEN---GITQISSTAESFHKQNGTGTPQV----ETNTSEDGESSGA--ND 94
PD V TV+ + IT T + Q G +V +++ + D S G N
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
Query: 95 SLRTPEQGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVK 154
S+ T + + P+ P+ D++ +I P + +TW + V
Sbjct: 1246 SVYTVKDDKESVPISDTIIPAVPPPT---DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRY 1302
Query: 155 HKMENEKTITVVH-QPWCN---ITGLRPATSYVFSI---------TPGIGNETWGDPRVI 201
++NE+ + + P N +T L P T YV S+ TP G + G
Sbjct: 1303 SPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
Query: 202 KVITEPIPVSDLRVALTGVRKAALSWSNGNGTASCRVLLESIGSHEELTQDSRLQVNISG 261
+ I + V R + + S E+ SR + ++
Sbjct: 1363 GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHF-----SGRPREDRVPHSRNSITLTN 1417
Query: 262 LKPGVQYNINPYLLQSNKTKGDPLGTEGGL-DASNTERSRAGSPTAPV--HDESLV---- 314
L PG +Y ++ L + +G + + D A +PT+ + D V
Sbjct: 1418 LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY 1477
Query: 315 -----------GPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANG---TEGQPQAI 360
PV + S+ T + GL+PG Y TVY+ G +P +I
Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATIS-GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
Query: 361 EFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVA-----GETDSSNLNVS 415
+RT + + ++ S+++ W S SS Y++ G T +
Sbjct: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLPS---SSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
Query: 416 EPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWS 475
+ I GL+ + Y ++V E P T T V I +AW
Sbjct: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWE 1653
Query: 476 SHDAESFQMHITQEGAGNSRVEI-----TTNQSIIIGGLFPGTKYCFEIV 520
S + + +T + E+ + + GL PG++Y +V
Sbjct: 1654 SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1703
Score = 42.7 bits (99), Expect = 8e-04
Identities = 77/437 (17%), Positives = 153/437 (35%), Gaps = 34/437 (7%)
Query: 115 SSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKY---VVKHKMENEKTITVVHQPWC 171
S T PSP D++ V ++ V + W ++A + Y+ V E+ + + + +
Sbjct: 904 SDTVPSPR-DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFA 962
Query: 172 NITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGN 231
+TGL P +Y F + + + P + T+ ++L+ + W+
Sbjct: 963 EVTGLSPGVTYYFKVF-AVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
Query: 232 GTASCRVLLESIGSHEELTQ----DSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGT 287
+ L + + Q S + + L+P +Y ++ ++ N+ G
Sbjct: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
Query: 288 ------EGGLDASNTE--RSRAGSPTAPVHDESLVGPVDPSSGQQ------SRDTEVLLV 333
+ NTE + P V PS G + S +++
Sbjct: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVS 1141
Query: 334 GLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDV-TAVNISATSLTLIWKVSDNE 392
GL PG Y T+ P + T ++ N LT+ W+ S
Sbjct: 1142 GLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP 1201
Query: 393 SSSNYTYKIHVAGETDSSNL----NVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFL 448
+ Y ++L + + L YN++V V D E P
Sbjct: 1202 DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD 1261
Query: 449 QVHTPPVPVSDFRVTVVSTTEIGLAWS---SHDAESFQMHITQEGAGNSRVEIT---TNQ 502
+ P +D R T + + + W+ S D +F + + E++ ++
Sbjct: 1262 TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDN 1321
Query: 503 SIIIGGLFPGTKYCFEI 519
++++ L PGT+Y +
Sbjct: 1322 AVVLTNLLPGTEYVVSV 1338
Score = 41.6 bits (96), Expect = 0.002
Identities = 80/339 (23%), Positives = 125/339 (36%), Gaps = 77/339 (22%)
Query: 111 QKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENE----KTITVV 166
Q PSS+GP VF + S P + + W + + KY+++ + +N K T+
Sbjct: 603 QTYPSSSGPVEVFITETPS-QPNSHPIQWNAPQPSHIS-KYILRWRPKNSVGRWKEATIP 660
Query: 167 -HQPWCNITGLRPATSYVFSITPGIGNETWGDPRVIK----------------VITEPIP 209
H I GL+P Y + I + +G V + V E P
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQL---ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
Query: 210 VSDLRVALTGVRKAA-----LSWSNGNGTAS-CRVLLESIGSHEELTQ----DSRLQVNI 259
S L V + +SW + + T S RV E +E + VNI
Sbjct: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNI 777
Query: 260 SGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAP----VHDESLV- 314
L PG +Y +N Y + + E L S ++ + +P P V D S+V
Sbjct: 778 PDLLPGRKYIVNVYQISED--------GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVV 829
Query: 315 ---GPVDPSSGQ--------QSRDTE---------VLLVGLEPGTRYNATVYSQAANGTE 354
P P +G + TE V L L+PG +YN T+Y+ N E
Sbjct: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN-QE 888
Query: 355 GQPQAIEFRTNAI-------QVFDVTAVNISATSLTLIW 386
P I+ T D+ V ++ +T++W
Sbjct: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW 927
Score = 37.7 bits (86), Expect = 0.027
Identities = 72/342 (21%), Positives = 121/342 (35%), Gaps = 34/342 (9%)
Query: 134 NVILTWKSNDTAASEYKYVVKHKMENEKTITVV---HQPWCNITGLRPATSYVFSITPGI 190
++ + W+S S Y+ + + + + GLRP + Y S+ +
Sbjct: 1647 SIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV-AL 1705
Query: 191 GNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGN-GTASCRVLL---ESIGSH 246
++ P + T +DL+ + W+ N RV + E G
Sbjct: 1706 HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1765
Query: 247 EE--LTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLD-ASNTERSRAGS 303
+E L DS V +SGL +Y ++ Y L+ T G L+ S R+R
Sbjct: 1766 KEINLAPDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTD 1824
Query: 304 PTAPV-------HDESLVG-PVD--PSSGQQSRDTEV-------LLVGLEPGTRYNATVY 346
T E++ G VD P++GQ + + GL+PGT Y +Y
Sbjct: 1825 ATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1884
Query: 347 SQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGE 406
+ N P I+ T ++ + + SL + W+ + Y K G
Sbjct: 1885 TLNDN-ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQ-PPRARITGYIIKYEKPGS 1942
Query: 407 TDSSNLNVSEP---RAVIPGLRSSTFYNITVCPVLGDIEGTP 445
+ P A I GL T Y I V + + + P
Sbjct: 1943 PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
Score = 35.8 bits (81), Expect = 0.10
Identities = 34/118 (28%), Positives = 52/118 (44%), Gaps = 7/118 (5%)
Query: 173 ITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNG 232
ITGL+P T Y + + + P VI T S+LR T +SW
Sbjct: 1870 ITGLQPGTDYKIYLYT-LNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRA 1928
Query: 233 TASCRVL-LESIGSH-EELTQDSR---LQVNISGLKPGVQYNINPYLLQSNKTKGDPL 285
+ ++ E GS E+ R + I+GL+PG +Y I L++N+ K +PL
Sbjct: 1929 RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ-KSEPL 1985
Score = 33.1 bits (74), Expect = 0.66
Identities = 70/308 (22%), Positives = 108/308 (35%), Gaps = 41/308 (13%)
Query: 110 SQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQP 169
SQ T P P D + T++++ W + Y+ V +E T + +
Sbjct: 806 SQTTAPDAPPDPTVD----QVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPET 861
Query: 170 WCNIT--GLRPATSYVFSI---------TP-GIGNETWGDPRVIKVITEPIPVSDLRVAL 217
++T L+P Y +I TP I ET G PR T P P V +
Sbjct: 862 ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPR---SDTVPSPRDLQFVEV 918
Query: 218 TGVRKAALSWSNGNGTASCRVLLESI---GSHEELTQDSR-LQVNISGLKPGVQYNINPY 273
T V+ + + RV + + G H + SR ++GL PGV Y +
Sbjct: 919 TDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVF 978
Query: 274 ----------LLQSNKTKGD-PLGTEGGLDASNTERSRAGSPTAPVHDESL-VGPVDPSS 321
L TK D P + + +T R P A + L VG
Sbjct: 979 AVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
Query: 322 GQQ----SRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNI 377
+Q ++ L L+P + Y TV A G + P+A T + N
Sbjct: 1039 PRQYNVGPSVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
Query: 378 SATSLTLI 385
T T++
Sbjct: 1097 EVTETTIV 1104
>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
Length = 2421
Score = 69.7 bits (169), Expect = 6e-12
Identities = 88/385 (22%), Positives = 150/385 (38%), Gaps = 53/385 (13%)
Query: 173 ITGLRPATSYVFSITPGIGNETWGDPRVI--KVITEPIPVSDLRVALTGVRKAALSWSNG 230
+T L P T YV SI G E P +I + +P DL V +SW
Sbjct: 1506 LTNLTPGTEYVVSIVALNGREE--SPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAP 1562
Query: 231 NGTASC-RVLLESIGSHEELTQ----DSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPL 285
T R+ G + + + S+ ISGLKPGV Y I Y + +GD
Sbjct: 1563 AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG---RGDSP 1619
Query: 286 GTEGGLDAS-NTERSRAGS-PTAPVHDESLVGPVDPSSGQQSR----------------- 326
+ + + TE + V D S+ PSS +
Sbjct: 1620 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1679
Query: 327 -----DTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATS 381
TE+ + GL+P Y +VY+Q +G E QP TN + + ++ S
Sbjct: 1680 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG-ESQPLVQTAVTNIDRPKGLAFTDVDVDS 1738
Query: 382 LTLIWKVSDNESSSNYTYKIHVAGETDSSN-----LNVSEPRAVIPGLRSSTFYNITVCP 436
+ + W+ + S Y++ + D + + E A + GLR + Y ++V
Sbjct: 1739 IKIAWESPQGQVS---RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA 1795
Query: 437 VLGDIEGTPGFLQVHTPPVPV-SDFRVTVVSTTEIGLAWSSHDAE--SFQMHITQEGAGN 493
+ D+E P + + +P +D + T V+ T + W+ + + +++ +T +
Sbjct: 1796 LHDDMESQP-LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG 1854
Query: 494 SRVEIT---TNQSIIIGGLFPGTKY 515
EI + S+++ GL TKY
Sbjct: 1855 PMKEINLAPDSSSVVVSGLMVATKY 1879
Score = 68.2 bits (165), Expect = 2e-11
Identities = 85/383 (22%), Positives = 151/383 (39%), Gaps = 42/383 (10%)
Query: 173 ITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAAL--SWSNG 230
+ L+PA+ Y S+ GN+ P+ V T P S + T V + + +W+
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
Query: 231 NGTASCRVLLESIGSH--EELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDP---- 284
+ S G E+T DS + +SGL PGV+Y +L+ + + P
Sbjct: 1111 PRIGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNK 1169
Query: 285 ----------LGTEGGLDASNTERSRAGSPTAPVHDESLVGPVDPSSGQQSRDTEVLLVG 334
L E D S S T + + P++GQQ E ++
Sbjct: 1170 VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRIT--TTPTNGQQGNSLEEVVHA 1227
Query: 335 ---------LEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLI 385
L PG YN +VY+ + E P + Q+ D++ V+I+ +S+ L
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYT-VKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLR 1286
Query: 386 WKVSDNESSSNYTYKIHVAGE---TDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIE 442
W ++ + Y + AGE ++ S + GL Y+I+V ++ E
Sbjct: 1287 WTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGE 1346
Query: 443 GTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWS---SHDAESFQMHITQEGAGNSRVEIT 499
P L T P +D R T + + + W+ S D +F + + E++
Sbjct: 1347 SAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1406
Query: 500 ---TNQSIIIGGLFPGTKYCFEI 519
++ ++++ L PGT+Y +
Sbjct: 1407 ISPSDNAVVLTNLLPGTEYVVSV 1429
Score = 61.2 bits (147), Expect = 2e-09
Identities = 74/306 (24%), Positives = 133/306 (43%), Gaps = 33/306 (10%)
Query: 244 GSHEELT-QDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTE---GGLDASNTERS 299
GS EL ++ V +S L+PGVQYNI Y ++ N+ + P+ + G S+T S
Sbjct: 851 GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQ-ESTPVVIQQETTGTPRSDTVPS 909
Query: 300 RAGSPTAPVHDESL-----------------VGPVD--PSSGQQ---SRDTEVLLVGLEP 337
V D + V PV+ GQ+ SR+T + GL P
Sbjct: 910 PRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSP 969
Query: 338 GTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNE-SSSN 396
G Y V++ ++G E +P + T ++ VN + +++ + W + +
Sbjct: 970 GVTYYFKVFA-VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYR 1028
Query: 397 YTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVP 456
T + G+ N+ S + + L+ ++ Y +++ + G+ E +P V T P
Sbjct: 1029 LTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE-SPKATGVFTTLQP 1087
Query: 457 VSDFRV--TVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVEITTNQ-SIIIGGLFPGT 513
S T V+ T I + W+ F++ + G + E+T++ SI++ GL PG
Sbjct: 1088 GSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGV 1147
Query: 514 KYCFEI 519
+Y + I
Sbjct: 1148 EYVYTI 1153
Score = 54.3 bits (129), Expect = 3e-07
Identities = 94/435 (21%), Positives = 163/435 (37%), Gaps = 51/435 (11%)
Query: 124 DIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENE--KTITVV-HQPWCNITGLRPAT 180
D++ V+ +PT+++++W + Y+ N + TV + I+GL+P
Sbjct: 1544 DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGV 1603
Query: 181 SY---VFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSW--SNGNGTAS 235
Y V+++T + P I TE S ++V ++ W S+ T
Sbjct: 1604 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGY 1663
Query: 236 CRVLLESIGSHEELTQDS---RLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLD 292
G T+ + + ++ I GL+P V+Y ++ Y Q+ + PL
Sbjct: 1664 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY-AQNPSGESQPLVQTA--- 1719
Query: 293 ASNTERSRAGSPTAPVHDESLVGPVDPSSGQQSR----------------------DTEV 330
+N +R + G V +S+ + GQ SR +
Sbjct: 1720 VTNIDRPK-GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778
Query: 331 LLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSD 390
L GL PG+ Y +V + + E QP T D+ ++ TSL+ W
Sbjct: 1779 ELQGLRPGSEYTVSVVA-LHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQW-TPP 1836
Query: 391 NESSSNYTYKI---HVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTP-- 445
N + Y ++ G NL V+ GL +T Y ++V + + P
Sbjct: 1837 NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ 1896
Query: 446 GFLQVHTPPVPVSDFRVTVVSTTEIGLAW--SSHDAESFQMHITQEGAGNSRVEITTN-- 501
G + P RVT + T I ++W + FQ+ G + ++ T
Sbjct: 1897 GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPD 1955
Query: 502 -QSIIIGGLFPGTKY 515
+S I GL PGT Y
Sbjct: 1956 VRSYTITGLQPGTDY 1970
Score = 51.6 bits (122), Expect = 2e-06
Identities = 92/461 (19%), Positives = 159/461 (34%), Gaps = 53/461 (11%)
Query: 104 NGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTI 163
NG + A T P D++ +I P + +TW + V ++NE+ +
Sbjct: 1343 NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDV 1402
Query: 164 TVVH-QPWCN---ITGLRPATSYVFSI---------TPGIGNETWGDPRVIKVITEPIPV 210
+ P N +T L P T YV S+ TP G + G + I
Sbjct: 1403 AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITA 1462
Query: 211 SDLRVALTGVRKAALSWSNGNGTASCRVLLESIGSHEELTQDSRLQVNISGLKPGVQYNI 270
+ V R + + S E+ SR + ++ L PG +Y +
Sbjct: 1463 NSFTVHWIAPRATITGYRIRHHPEHF-----SGRPREDRVPHSRNSITLTNLTPGTEYVV 1517
Query: 271 NPYLLQSNKTKGDPLGTEGGL-DASNTERSRAGSPTAPV--HDESLV------------- 314
+ L + +G + + D A +PT+ + D V
Sbjct: 1518 SIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1577
Query: 315 --GPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANG---TEGQPQAIEFRTNAIQV 369
PV + S+ T + GL+PG Y TVY+ G +P +I +RT +
Sbjct: 1578 GNSPVQEFTVPGSKSTATIS-GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP 1636
Query: 370 FDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVA-----GETDSSNLNVSEPRAVIPGL 424
+ ++ S+++ W S SS Y++ G T + + I GL
Sbjct: 1637 SQMQVTDVQDNSISVKWLPS---SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1693
Query: 425 RSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQM 484
+ + Y ++V E P T T V I +AW S + +
Sbjct: 1694 QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRY 1753
Query: 485 HITQEGAGNSRVEI-----TTNQSIIIGGLFPGTKYCFEIV 520
+T + E+ + + GL PG++Y +V
Sbjct: 1754 RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1794
Score = 49.7 bits (117), Expect = 7e-06
Identities = 47/208 (22%), Positives = 79/208 (37%), Gaps = 13/208 (6%)
Query: 325 SRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTL 384
S T V + L PG +Y VY + +G + + T D T + TS+ +
Sbjct: 770 STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVV 829
Query: 385 IWKVSDNESSS-NYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEG 443
W + Y V G + NL + + L+ YNIT+ V + E
Sbjct: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
Query: 444 TPGFLQVHTPPVPVS-------DFRVTVVSTTEIGLAWSSHDA-----ESFQMHITQEGA 491
TP +Q T P S D + V+ ++ + W+ ++ + + G
Sbjct: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
Query: 492 GNSRVEITTNQSIIIGGLFPGTKYCFEI 519
R+ I+ N + GL PG Y F++
Sbjct: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKV 977
Score = 47.0 bits (110), Expect = 4e-05
Identities = 86/457 (18%), Positives = 163/457 (35%), Gaps = 37/457 (8%)
Query: 115 SSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKY---VVKHKMENEKTITVVHQPWC 171
S T PSP D++ V ++ V + W ++A + Y+ V E+ + + + +
Sbjct: 904 SDTVPSPR-DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFA 962
Query: 172 NITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGN 231
+TGL P +Y F + + + P + T+ ++L+ + W+
Sbjct: 963 EVTGLSPGVTYYFKVF-AVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
Query: 232 GTASCRVLLESIGSHEELTQ----DSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGT 287
+ L + + Q S + + L+P +Y ++ ++ N+ G
Sbjct: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
Query: 288 ------EGGLDASNTE--RSRAGSPTAPVHDESLVGPVDPSSGQQ------SRDTEVLLV 333
+ NTE + P V PS G + S +++
Sbjct: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVS 1141
Query: 334 GLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDV-TAVNISATSLTLIWKVSDNE 392
GL PG Y T+ P + T ++ N LT+ W+ S
Sbjct: 1142 GLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP 1201
Query: 393 SSSNYTYKIHVAGETDSSNL----NVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFL 448
+ Y ++L + + L YN++V V D E P
Sbjct: 1202 DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP-IS 1260
Query: 449 QVHTPPVP-VSDFRVTVVSTTEIGLAWSSHDAES---FQMHITQEGAGNSRVEITTNQSI 504
P VP ++D ++ + IGL W+ ++ + +++ + G G E + S+
Sbjct: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
Query: 505 ---IIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRT 538
+ GL PG Y ++ NG E A T+ +T
Sbjct: 1321 GYYTVTGLEPGIDYDISVITL-INGGESAPTTLTQQT 1356
Score = 41.6 bits (96), Expect = 0.002
Identities = 80/339 (23%), Positives = 125/339 (36%), Gaps = 77/339 (22%)
Query: 111 QKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENE----KTITVV 166
Q PSS+GP VF + S P + + W + + KY+++ + +N K T+
Sbjct: 603 QTYPSSSGPVEVFITETPS-QPNSHPIQWNAPQPSHIS-KYILRWRPKNSVGRWKEATIP 660
Query: 167 -HQPWCNITGLRPATSYVFSITPGIGNETWGDPRVIK----------------VITEPIP 209
H I GL+P Y + I + +G V + V E P
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQL---ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
Query: 210 VSDLRVALTGVRKAA-----LSWSNGNGTAS-CRVLLESIGSHEELTQ----DSRLQVNI 259
S L V + +SW + + T S RV E +E + VNI
Sbjct: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNI 777
Query: 260 SGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAP----VHDESLV- 314
L PG +Y +N Y + + E L S ++ + +P P V D S+V
Sbjct: 778 PDLLPGRKYIVNVYQISED--------GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVV 829
Query: 315 ---GPVDPSSGQ--------QSRDTE---------VLLVGLEPGTRYNATVYSQAANGTE 354
P P +G + TE V L L+PG +YN T+Y+ N E
Sbjct: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN-QE 888
Query: 355 GQPQAIEFRTNAI-------QVFDVTAVNISATSLTLIW 386
P I+ T D+ V ++ +T++W
Sbjct: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW 927
Score = 37.7 bits (86), Expect = 0.027
Identities = 72/342 (21%), Positives = 121/342 (35%), Gaps = 34/342 (9%)
Query: 134 NVILTWKSNDTAASEYKYVVKHKMENEKTITVV---HQPWCNITGLRPATSYVFSITPGI 190
++ + W+S S Y+ + + + + GLRP + Y S+ +
Sbjct: 1738 SIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV-AL 1796
Query: 191 GNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGN-GTASCRVLL---ESIGSH 246
++ P + T +DL+ + W+ N RV + E G
Sbjct: 1797 HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1856
Query: 247 EE--LTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLD-ASNTERSRAGS 303
+E L DS V +SGL +Y ++ Y L+ T G L+ S R+R
Sbjct: 1857 KEINLAPDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTD 1915
Query: 304 PTAPV-------HDESLVG-PVD--PSSGQQSRDTEV-------LLVGLEPGTRYNATVY 346
T E++ G VD P++GQ + + GL+PGT Y +Y
Sbjct: 1916 ATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1975
Query: 347 SQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGE 406
+ N P I+ T ++ + + SL + W+ + Y K G
Sbjct: 1976 TLNDN-ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQ-PPRARITGYIIKYEKPGS 2033
Query: 407 TDSSNLNVSEP---RAVIPGLRSSTFYNITVCPVLGDIEGTP 445
+ P A I GL T Y I V + + + P
Sbjct: 2034 PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
Score = 35.8 bits (81), Expect = 0.10
Identities = 34/118 (28%), Positives = 52/118 (44%), Gaps = 7/118 (5%)
Query: 173 ITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNG 232
ITGL+P T Y + + + P VI T S+LR T +SW
Sbjct: 1961 ITGLQPGTDYKIYLYT-LNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRA 2019
Query: 233 TASCRVL-LESIGSH-EELTQDSR---LQVNISGLKPGVQYNINPYLLQSNKTKGDPL 285
+ ++ E GS E+ R + I+GL+PG +Y I L++N+ K +PL
Sbjct: 2020 RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ-KSEPL 2076
Score = 33.1 bits (74), Expect = 0.66
Identities = 70/308 (22%), Positives = 108/308 (35%), Gaps = 41/308 (13%)
Query: 110 SQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQP 169
SQ T P P D + T++++ W + Y+ V +E T + +
Sbjct: 806 SQTTAPDAPPDPTVD----QVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPET 861
Query: 170 WCNIT--GLRPATSYVFSI---------TP-GIGNETWGDPRVIKVITEPIPVSDLRVAL 217
++T L+P Y +I TP I ET G PR T P P V +
Sbjct: 862 ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPR---SDTVPSPRDLQFVEV 918
Query: 218 TGVRKAALSWSNGNGTASCRVLLESI---GSHEELTQDSR-LQVNISGLKPGVQYNINPY 273
T V+ + + RV + + G H + SR ++GL PGV Y +
Sbjct: 919 TDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVF 978
Query: 274 ----------LLQSNKTKGD-PLGTEGGLDASNTERSRAGSPTAPVHDESL-VGPVDPSS 321
L TK D P + + +T R P A + L VG
Sbjct: 979 AVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
Query: 322 GQQ----SRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNI 377
+Q ++ L L+P + Y TV A G + P+A T + N
Sbjct: 1039 PRQYNVGPSVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
Query: 378 SATSLTLI 385
T T++
Sbjct: 1097 EVTETTIV 1104
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 65.9 bits (159), Expect = 9e-11
Identities = 100/454 (22%), Positives = 176/454 (38%), Gaps = 67/454 (14%)
Query: 112 KTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKY--------------VVKHKM 157
K +TG +++ VS + ++ L W++ A Y+ V K +
Sbjct: 886 KETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQ 945
Query: 158 ENEKTITVVHQPWCNITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVAL 217
KT +TGLRP T Y ++ + + +P I TE DL+V+
Sbjct: 946 ATTKT---------TLTGLRPGTEYGIGVS-AVKEDKESNPATINAATELDTPKDLQVSE 995
Query: 218 TGVRKAALSWSNGNGTASCRVLLESIGSHE----ELTQDSRLQVNISGLKPGVQYNINPY 273
T L W L S+ + + +L +++ V + GL+PG +YN+
Sbjct: 996 TAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYV-LRGLEPGQEYNVL-L 1053
Query: 274 LLQSNKTKGDPL----GTEGGLDASNTERSRAG--------SPTAPVHDESLVGPVDPSS 321
+ + K P TE + N + G + ++ ++ + +
Sbjct: 1054 TAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANK 1113
Query: 322 GQQSRDTEVL-------LVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAI-QVFDVT 373
+ +R+ V + GL+ T Y ++Y G + E T + +V
Sbjct: 1114 VEAARNLTVPGSLRAVDIPGLKAATPYTVSIYG-VIQGYRTPVLSAEASTGETPNLGEVV 1172
Query: 374 AVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAV----IPGLRSSTF 429
+ +L L W E + Y + +T + N++ P + +PGL+++T
Sbjct: 1173 VAEVGWDALKLNWTAP--EGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATH 1230
Query: 430 YNITVCPVLGDIEGTPGFLQVHTPPVP-VSDFRVTVVSTTEIGLAWSSHDAESFQMHITQ 488
Y IT+ V D TP ++V T VP + + VT VS + L W++ D Q I
Sbjct: 1231 YTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQV 1290
Query: 489 EGAGNSRVEITTN-------QSIIIGGLFPGTKY 515
+ A +VE N +S+ I GL GT Y
Sbjct: 1291 QEA--DQVEEAHNLTVPGSLRSMEIPGLRAGTPY 1322
Score = 60.8 bits (146), Expect = 3e-09
Identities = 85/364 (23%), Positives = 150/364 (41%), Gaps = 32/364 (8%)
Query: 104 NGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTW--KSNDTAASEYKYVVKHKMENEK 161
N T G K ++T I+ ++ T ++TW + E Y +K +
Sbjct: 788 NNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRT 847
Query: 162 TITVVH-QPWCNITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGV 220
TI + + +I L+P T Y S+ G+ + + P + RV+ T
Sbjct: 848 TIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTD- 906
Query: 221 RKAALSWSNGNGTA-SCRVLLESI--GSHEEL----TQDSRLQVNISGLKPGVQYNINPY 273
L W NG S R+ I G H E+ +Q + + ++GL+PG +Y I
Sbjct: 907 NSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVS 966
Query: 274 LLQSNK-------TKGDPLGTEGGLDASNTERSRA----GSPTAPVHDESL--VGPVDPS 320
++ +K L T L S T + +P A L P
Sbjct: 967 AVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQW 1026
Query: 321 SGQQ--SRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRT-NAIQVFDVTAVNI 377
G Q T +L GLEPG YN + ++ + +P ++ T A ++ ++T +
Sbjct: 1027 VGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGR-HKSKPARVKASTEQAPELENLTVTEV 1085
Query: 378 SATSLTLIWKVSDNESSSNYTYKIHVAGETDSS-NLNV-SEPRAV-IPGLRSSTFYNITV 434
L L W +D ++ ++ ++ A + +++ NL V RAV IPGL+++T Y +++
Sbjct: 1086 GWDGLRLNWTAAD-QAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSI 1144
Query: 435 CPVL 438
V+
Sbjct: 1145 YGVI 1148
Score = 52.8 bits (125), Expect = 8e-07
Identities = 94/440 (21%), Positives = 175/440 (39%), Gaps = 58/440 (13%)
Query: 120 SPVFDIKAVSISPTNVILTWKSNDTAASEYKYV----------VKHKMENEKTITVVHQP 169
SP D+ ++ V L W N+ +EY V ++ ++ ++T T++ +
Sbjct: 624 SPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQE- 681
Query: 170 WCNITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSN 229
L P Y + + N+ P +V T L+ + W
Sbjct: 682 ------LEPGVEYFIRVFAILENKK-SIPVSARVATYLPAPEGLKFKSIKETSVEVEWDP 734
Query: 230 GN-GTASCRVLLESIGSHEE--LTQDSR---LQVNISGLKPGVQYNINPYLLQSNKTKGD 283
+ + ++ ++ +E +T+ R +GL PG +Y I+ +++++N T+G
Sbjct: 735 LDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNN-TRGP 793
Query: 284 PLG--TEGGLDA-SNTERSRAGSPTA------PVHD----ESLVG----PVDPSSGQQSR 326
L T LDA S E TA P+ + E G P D ++ +
Sbjct: 794 GLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTE 853
Query: 327 DTEVLLVG-LEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLI 385
D +G L+P T Y ++ S+ + P F T ++ V+ + S+TL
Sbjct: 854 DENQYSIGNLKPDTEYEVSLISRRGD-MSSNPAKETFTTGLDAPRNLRRVSQTDNSITLE 912
Query: 386 WKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRA-------VIPGLRSSTFYNITVCPVL 438
W+ N ++ +Y+I A + + V P++ + GLR T Y I V V
Sbjct: 913 WR---NGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVK 969
Query: 439 GDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDA--ESFQMHITQEGAGNSRV 496
D E P + T D +V+ + T + L W + A + ++++ + V
Sbjct: 970 EDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGV 1029
Query: 497 EITTN-QSIIIGGLFPGTKY 515
++ N S ++ GL PG +Y
Sbjct: 1030 QLPRNTTSYVLRGLEPGQEY 1049
>gi|241896926 protein tyrosine phosphatase, receptor type, H isoform
2 precursor [Homo sapiens]
Length = 937
Score = 64.3 bits (155), Expect = 3e-10
Identities = 114/508 (22%), Positives = 189/508 (37%), Gaps = 71/508 (13%)
Query: 53 TGENGITQISSTAESFHKQNGTGTPQVETNTSEDGESSGANDSLRTPEQGSNGTDGASQK 112
TG+ G T+ +T + +G G + T S E G N S+ T
Sbjct: 68 TGDGGTTETRNTTATNVTVDGLGPGSLYT-CSVWVEKDGVNSSVGT-------------- 112
Query: 113 TPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYK-YVVKHKMENEK--TITVVHQP 169
++T P+PV ++ + + +++ LTW+ D + Y V++ + + T + H
Sbjct: 113 VTTATAPNPVRNLTVEAQTNSSIALTWEVPDGPDPQNSTYGVEYTGDGGRAGTRSTAHT- 171
Query: 170 WCNIT--GLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSW 227
NIT L P YVFS+ G N T P PV +L + AL W
Sbjct: 172 --NITVDRLEPGCLYVFSVWVG-KNGINSSRETRNATTAPNPVRNLHMETQTNSSIALCW 228
Query: 228 SNGNGTA----SCRVLLESIGSHEELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGD 283
+G + V G E + V L+PG Y + + + N +G
Sbjct: 229 EVPDGPYPQDYTYWVEYTGDGGGTETRNTTNTSVTAERLEPGTLYTFSVWA-EKNGARGS 287
Query: 284 ----PLGTEGGLDASNTERSRAGS--------PTAPVHDESLV-------GPVDPSSGQQ 324
+ T S +++ S P P G DP + Q
Sbjct: 288 RQNVSISTVPNAVTSLSKQDWTNSTIALRWTAPQGPGQSSYSYWVSWVREGMTDPRT-QS 346
Query: 325 SRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTL 384
+ T++ L LE G+ Y+ TV+++ N G + T +V D+ + S+ L
Sbjct: 347 TSGTDITLKELEAGSLYHLTVWAER-NEVRGYNSTLTAATAPNEVTDLQNETQTKNSVML 405
Query: 385 IWKVSDNESSSNYTYKIHVA-------GETDSSN-----LNVSEPRAVIPGLRSSTFYNI 432
WK + S Y Y + A G+ +N +E + L T YN
Sbjct: 406 WWKAPGDPHSQLYVYWVQWASKGHPRRGQDPQANWVNQTSRTNETWYKVEALEPGTLYNF 465
Query: 433 TVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTE---IGLAWSSHDA--ESFQMHIT 487
TV D+ + L T P V+ + VST+ + L WS E+F++ +
Sbjct: 466 TVWAERNDVASSTQSLCASTYPDTVT--ITSCVSTSAGYGVNLIWSCPQGGYEAFELEV- 522
Query: 488 QEGAGNSRVEITTNQSIIIGGLFPGTKY 515
G S+ + +++ + GL P Y
Sbjct: 523 -GGQRGSQDRSSCGEAVSVLGLGPARSY 549
Score = 59.7 bits (143), Expect = 7e-09
Identities = 50/213 (23%), Positives = 85/213 (39%), Gaps = 9/213 (4%)
Query: 328 TEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWK 387
T V + GL PG+ Y +V+ + +G + T V ++T + +S+ L W+
Sbjct: 82 TNVTVDGLGPGSLYTCSVWVEK-DGVNSSVGTVTTATAPNPVRNLTVEAQTNSSIALTWE 140
Query: 388 VSDNESSSNYTYKIHVAGETDSSNL-NVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPG 446
V D N TY + G+ + + + + L Y +V I +
Sbjct: 141 VPDGPDPQNSTYGVEYTGDGGRAGTRSTAHTNITVDRLEPGCLYVFSVWVGKNGINSSRE 200
Query: 447 FLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAE-----SFQMHITQEGAGNSRVEITTN 501
T P PV + + + + I L W D ++ + T +G G + TTN
Sbjct: 201 TRNATTAPNPVRNLHMETQTNSSIALCWEVPDGPYPQDYTYWVEYTGDGGG-TETRNTTN 259
Query: 502 QSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTV 534
S+ L PGT Y F + + NG G+ + V
Sbjct: 260 TSVTAERLEPGTLYTFSVWAE-KNGARGSRQNV 291
Score = 58.5 bits (140), Expect = 1e-08
Identities = 80/410 (19%), Positives = 150/410 (36%), Gaps = 62/410 (15%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQPWCNIT--GL 176
P+P ++ + + +++ L+W+ D S+ + T + N+T GL
Sbjct: 30 PNPGRNLTVETQTTSSISLSWEVPDGLDSQNSNYWVQCTGDGGTTETRNTTATNVTVDGL 89
Query: 177 RPATSYVFSI---TPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNG- 232
P + Y S+ G+ + + T P PV +L V AL+W +G
Sbjct: 90 GPGSLYTCSVWVEKDGVNSSVG----TVTTATAPNPVRNLTVEAQTNSSIALTWEVPDGP 145
Query: 233 ---TASCRVLLESIGSHEELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEG 289
++ V G + + + L+PG Y + ++
Sbjct: 146 DPQNSTYGVEYTGDGGRAGTRSTAHTNITVDRLEPGCLYVFSVWV--------------- 190
Query: 290 GLDASNTERSRAGSPTAP-----VHDESLV------------GP-----------VDPSS 321
G + N+ R + TAP +H E+ GP
Sbjct: 191 GKNGINSSRETRNATTAPNPVRNLHMETQTNSSIALCWEVPDGPYPQDYTYWVEYTGDGG 250
Query: 322 GQQSRDT---EVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNIS 378
G ++R+T V LEPGT Y +V+++ NG G Q + T V ++ + +
Sbjct: 251 GTETRNTTNTSVTAERLEPGTLYTFSVWAEK-NGARGSRQNVSISTVPNAVTSLSKQDWT 309
Query: 379 ATSLTLIWKVSDNESSSNYTYKIHVA--GETDSSNLNVSEPRAVIPGLRSSTFYNITVCP 436
+++ L W S+Y+Y + G TD + S + L + + Y++TV
Sbjct: 310 NSTIALRWTAPQGPGQSSYSYWVSWVREGMTDPRTQSTSGTDITLKELEAGSLYHLTVWA 369
Query: 437 VLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHI 486
++ G L T P V+D + + + L W + Q+++
Sbjct: 370 ERNEVRGYNSTLTAATAPNEVTDLQNETQTKNSVMLWWKAPGDPHSQLYV 419
Score = 53.9 bits (128), Expect = 4e-07
Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 8/169 (4%)
Query: 371 DVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNL-NVSEPRAVIPGLRSSTF 429
++T + +S++L W+V D S N Y + G+ ++ N + + GL +
Sbjct: 35 NLTVETQTTSSISLSWEVPDGLDSQNSNYWVQCTGDGGTTETRNTTATNVTVDGLGPGSL 94
Query: 430 YNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDA-----ESFQM 484
Y +V + + G + T P PV + V + + I L W D ++ +
Sbjct: 95 YTCSVWVEKDGVNSSVGTVTTATAPNPVRNLTVEAQTNSSIALTWEVPDGPDPQNSTYGV 154
Query: 485 HITQEGAGNSRVEITTNQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRT 533
T +G G + T + +I + L PG Y F V G NG + T
Sbjct: 155 EYTGDG-GRAGTRSTAHTNITVDRLEPGCLYVFS-VWVGKNGINSSRET 201
Score = 50.8 bits (120), Expect = 3e-06
Identities = 69/337 (20%), Positives = 116/337 (34%), Gaps = 31/337 (9%)
Query: 207 PIPVSDLRVALTGVRKAALSWSNGNGTASCR----VLLESIGSHEELTQDSRLQVNISGL 262
P P +L V +LSW +G S V G E + V + GL
Sbjct: 30 PNPGRNLTVETQTTSSISLSWEVPDGLDSQNSNYWVQCTGDGGTTETRNTTATNVTVDGL 89
Query: 263 KPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSRAGS-------------PTAPVH 309
PG Y + ++ + +GT A N R+ P P
Sbjct: 90 GPGSLYTCSVWVEKDGVNSS--VGTVTTATAPNPVRNLTVEAQTNSSIALTWEVPDGPDP 147
Query: 310 DESLVGPVDPSSG-----QQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRT 364
S G G + + T + + LEPG Y +V+ NG + T
Sbjct: 148 QNSTYGVEYTGDGGRAGTRSTAHTNITVDRLEPGCLYVFSVWV-GKNGINSSRETRNATT 206
Query: 365 NAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNL-NVSEPRAVIPG 423
V ++ + +S+ L W+V D +YTY + G+ + N +
Sbjct: 207 APNPVRNLHMETQTNSSIALCWEVPDGPYPQDYTYWVEYTGDGGGTETRNTTNTSVTAER 266
Query: 424 LRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSS-----HD 478
L T Y +V G+ + + T P V+ + + I L W++
Sbjct: 267 LEPGTLYTFSVWAEKNGARGSRQNVSISTVPNAVTSLSKQDWTNSTIALRWTAPQGPGQS 326
Query: 479 AESFQMHITQEGAGNSRVEITTNQSIIIGGLFPGTKY 515
+ S+ + +EG + R + T+ I + L G+ Y
Sbjct: 327 SYSYWVSWVREGMTDPRTQSTSGTDITLKELEAGSLY 363
Score = 43.9 bits (102), Expect = 4e-04
Identities = 82/388 (21%), Positives = 152/388 (39%), Gaps = 44/388 (11%)
Query: 102 GSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTA-ASEYKYVVKHKMENE 160
G NG + + + ++T P+PV ++ + + +++ L W+ D +Y Y V++ +
Sbjct: 191 GKNGINSSRETRNATTAPNPVRNLHMETQTNSSIALCWEVPDGPYPQDYTYWVEYTGDGG 250
Query: 161 KTITVVHQPWCNITG--LRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALT 218
T T + ++T L P T Y FS+ N G + + + T P V+ L
Sbjct: 251 GTETR-NTTNTSVTAERLEPGTLYTFSVWAE-KNGARGSRQNVSISTVPNAVTSLSKQDW 308
Query: 219 GVRKAALSWS--NGNGTASCRVLLESI--GSHEELTQD-SRLQVNISGLKPGVQYNINPY 273
AL W+ G G +S + + G + TQ S + + L+ G Y++ +
Sbjct: 309 TNSTIALRWTAPQGPGQSSYSYWVSWVREGMTDPRTQSTSGTDITLKELEAGSLYHLTVW 368
Query: 274 LLQS-----NKTKGDPLGTEGGLDASNTERSRAG------SPTAPVHDESLVGPVD---- 318
++ N T D N +++ +P P H + V V
Sbjct: 369 AERNEVRGYNSTLTAATAPNEVTDLQNETQTKNSVMLWWKAPGDP-HSQLYVYWVQWASK 427
Query: 319 --PSSGQ-----------QSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTN 365
P GQ ++ +T + LEPGT YN TV+++ N Q++ T
Sbjct: 428 GHPRRGQDPQANWVNQTSRTNETWYKVEALEPGTLYNFTVWAE-RNDVASSTQSLCASTY 486
Query: 366 AIQVFDVTAVNISA-TSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAVIPGL 424
V + V+ SA + LIW + +++ V G+ S + + + GL
Sbjct: 487 PDTVTITSCVSTSAGYGVNLIWSCPQGGYEA---FELEVGGQRGSQDRSSCGEAVSVLGL 543
Query: 425 RSSTFYNITVCPVLGDIEGTPGFLQVHT 452
+ Y T+ + ++ + HT
Sbjct: 544 GPARSYPATITTIWDGMKVVSHSVVCHT 571
>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
Length = 2296
Score = 63.5 bits (153), Expect = 5e-10
Identities = 94/384 (24%), Positives = 141/384 (36%), Gaps = 50/384 (13%)
Query: 173 ITGLRPATSYVFSITPGIGNETWGDPRVI--KVITEPIPVSDLRVALTGVRKAALSWSNG 230
+T L P T YV SI G E P +I + +P DL V +SW
Sbjct: 1415 LTNLTPGTEYVVSIVALNGREE--SPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAP 1471
Query: 231 NGTASC-RVLLESIGSHEELTQ----DSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPL 285
T R+ G + + + S+ ISGLKPGV Y I Y + +GD
Sbjct: 1472 AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG---RGDSP 1528
Query: 286 GTEGGLDAS-NTERSRAGS-PTAPVHDESLVGPVDPSSGQQS------------------ 325
+ + + TE + V D S+ PSS +
Sbjct: 1529 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588
Query: 326 ----RDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATS 381
TE+ + GL+P Y +VY+Q +G E QP T D+ ++ TS
Sbjct: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG-ESQPLVQTAVTTIPAPTDLKFTQVTPTS 1647
Query: 382 LTLIWKVSDNESSSNYTYKI---HVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVL 438
L+ W N + Y ++ G NL V+ GL +T Y ++V +
Sbjct: 1648 LSAQW-TPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1706
Query: 439 GDIEGTP--GFLQVHTPPVPVSDFRVTVVSTTEIGLAW--SSHDAESFQMHITQEGAGNS 494
+ P G + P RVT + T I ++W + FQ+ G +
Sbjct: 1707 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQT 1765
Query: 495 RVEITTN---QSIIIGGLFPGTKY 515
++ T +S I GL PGT Y
Sbjct: 1766 PIQRTIKPDVRSYTITGLQPGTDY 1789
Score = 61.2 bits (147), Expect = 2e-09
Identities = 71/306 (23%), Positives = 130/306 (42%), Gaps = 33/306 (10%)
Query: 244 GSHEELT-QDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEG---GLDASNTERS 299
GS EL ++ V +S L+PGVQYNI Y ++ N+ + P+ + G S+T S
Sbjct: 851 GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQ-ESTPVVIQQETTGTPRSDTVPS 909
Query: 300 RAGSPTAPVHDESL-----------------VGPVD--PSSGQQ---SRDTEVLLVGLEP 337
V D + V PV+ GQ+ SR+T + GL P
Sbjct: 910 PRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSP 969
Query: 338 GTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSS-N 396
G Y V++ ++G E +P + T ++ VN + +++ + W + +
Sbjct: 970 GVTYYFKVFA-VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYR 1028
Query: 397 YTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEG--TPGFLQVHTPP 454
T + G+ N+ S + + L+ ++ Y +++ + G+ E G P
Sbjct: 1029 LTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG 1088
Query: 455 VPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVEITTNQ-SIIIGGLFPGT 513
+ + V TT I + W+ F++ + G + E+T++ SI++ GL PG
Sbjct: 1089 SSIPPYNTEVTETT-IVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGV 1147
Query: 514 KYCFEI 519
+Y + I
Sbjct: 1148 EYVYTI 1153
Score = 58.5 bits (140), Expect = 1e-08
Identities = 100/467 (21%), Positives = 163/467 (34%), Gaps = 53/467 (11%)
Query: 110 SQKTPSSTG------PSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTI 163
+Q++P +TG P ++ T +++TW +K V+ E
Sbjct: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG--FKLGVRPSQGGEAPR 1129
Query: 164 TVVHQPWCNI-TGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVAL---TG 219
V + +GL P YV++I + P V KV+T P ++L + TG
Sbjct: 1130 EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTG 1189
Query: 220 VRKAALSWSNGNGTASCRVLL-----ESIGSHEELTQDSRLQVNISGLKPGVQYNINPYL 274
V + S R+ + S EE+ + L PG++YN++ Y
Sbjct: 1190 VLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
Query: 275 LQSNKTK--------------GDPLGTEGGLDASNTERSRAGS--------PTAPVHDES 312
++ +K D T G D + S +PV +E
Sbjct: 1250 VKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1309
Query: 313 LVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDV 372
V + S D V+L L PGT Y +V S E P +T +
Sbjct: 1310 DVAELSISPS----DNAVVLTNLLPGTEYVVSV-SSVYEQHESTPLRGRQKTGLDSPTGI 1364
Query: 373 TAVNISATSLTLIWKVSDNESSSNYT---YKIHVAGETDSSNLNVSEPRAVIPGLRSSTF 429
+I+A S T+ W ++ + + Y + H +G + S + L T
Sbjct: 1365 DFSDITANSFTVHW-IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
Query: 430 YNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQ- 488
Y +++ + G E Q T D V + T + ++W + IT
Sbjct: 1424 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG 1483
Query: 489 EGAGNSRVEITT----NQSIIIGGLFPGTKYCFEIVPKGPNGTEGAS 531
E GNS V+ T + I GL PG Y + G AS
Sbjct: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
Score = 51.2 bits (121), Expect = 2e-06
Identities = 87/383 (22%), Positives = 143/383 (37%), Gaps = 41/383 (10%)
Query: 173 ITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAAL--SWSNG 230
+ L+PA+ Y S+ GN+ P+ V T P S + T V + + +W+
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
Query: 231 NGTASCRVLLESIGSH--EELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDP---- 284
+ S G E+T DS + +SGL PGV+Y +L+ + + P
Sbjct: 1111 PRIGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNK 1169
Query: 285 ----------LGTEGGLDASNTERSRAGSPTAPVHDESLVGPVDPSSGQQSRDTEVLL-- 332
L E D S S T + + P++GQQ E ++
Sbjct: 1170 VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRIT--TTPTNGQQGNSLEEVVHA 1227
Query: 333 -------VGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLI 385
L PG YN +VY+ + E P + D+ NI ++ +
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYT-VKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVT 1286
Query: 386 WKVSDNESSSNYTYKIH-VAGETDSSNLNV--SEPRAVIPGLRSSTFYNITVCPVLGDIE 442
W + +N+ + V E D + L++ S+ V+ L T Y ++V V E
Sbjct: 1287 WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
Query: 443 GTPGFLQVHT---PPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVEIT 499
TP + T P + +T S T +A + H + +G R +
Sbjct: 1347 STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
Query: 500 --TNQSIIIGGLFPGTKYCFEIV 520
+ SI + L PGT+Y IV
Sbjct: 1407 PHSRNSITLTNLTPGTEYVVSIV 1429
Score = 49.7 bits (117), Expect = 7e-06
Identities = 47/208 (22%), Positives = 79/208 (37%), Gaps = 13/208 (6%)
Query: 325 SRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTL 384
S T V + L PG +Y VY + +G + + T D T + TS+ +
Sbjct: 770 STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVV 829
Query: 385 IWKVSDNESSS-NYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEG 443
W + Y V G + NL + + L+ YNIT+ V + E
Sbjct: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
Query: 444 TPGFLQVHTPPVPVS-------DFRVTVVSTTEIGLAWSSHDA-----ESFQMHITQEGA 491
TP +Q T P S D + V+ ++ + W+ ++ + + G
Sbjct: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
Query: 492 GNSRVEITTNQSIIIGGLFPGTKYCFEI 519
R+ I+ N + GL PG Y F++
Sbjct: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKV 977
Score = 45.4 bits (106), Expect = 1e-04
Identities = 82/434 (18%), Positives = 157/434 (36%), Gaps = 39/434 (8%)
Query: 124 DIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENE--KTITVV-HQPWCNITGLRPAT 180
D++ V+ +PT+++++W + Y+ N + TV + I+GL+P
Sbjct: 1453 DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGV 1512
Query: 181 SY---VFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSW--SNGNGTAS 235
Y V+++T + P I TE S ++V ++ W S+ T
Sbjct: 1513 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGY 1572
Query: 236 CRVLLESIGSHEELTQDS---RLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEG--G 290
G T+ + + ++ I GL+P V+Y ++ Y Q+ + PL
Sbjct: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY-AQNPSGESQPLVQTAVTT 1631
Query: 291 LDASNTERSRAGSPTA-----------------PVHDESLVGPVDPSSGQQSRDTEVLLV 333
+ A + +PT+ V + GP+ + V++
Sbjct: 1632 IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM-KEINLAPDSSSVVVS 1690
Query: 334 GLEPGTRYNATVYSQAANGTEGQPQ-AIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNE 392
GL T+Y +VY+ T Q + N + + T++T+ W+
Sbjct: 1691 GLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET 1750
Query: 393 SSSNYTYKIHVAGETDSSNLNVSEPRA-VIPGLRSSTFYNITVCPVLGDIEGTPGFLQVH 451
+ + G+T + R+ I GL+ T Y I + + + +P +
Sbjct: 1751 ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1810
Query: 452 TPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVEITTN-----QSIII 506
T S+ R + + ++W A I E G+ E+ I
Sbjct: 1811 TAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 1870
Query: 507 GGLFPGTKYCFEIV 520
GL PGT+Y ++
Sbjct: 1871 TGLEPGTEYTIYVI 1884
Score = 42.7 bits (99), Expect = 8e-04
Identities = 77/437 (17%), Positives = 153/437 (35%), Gaps = 34/437 (7%)
Query: 115 SSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKY---VVKHKMENEKTITVVHQPWC 171
S T PSP D++ V ++ V + W ++A + Y+ V E+ + + + +
Sbjct: 904 SDTVPSPR-DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFA 962
Query: 172 NITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGN 231
+TGL P +Y F + + + P + T+ ++L+ + W+
Sbjct: 963 EVTGLSPGVTYYFKVF-AVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
Query: 232 GTASCRVLLESIGSHEELTQ----DSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGT 287
+ L + + Q S + + L+P +Y ++ ++ N+ G
Sbjct: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
Query: 288 ------EGGLDASNTE--RSRAGSPTAPVHDESLVGPVDPSSGQQ------SRDTEVLLV 333
+ NTE + P V PS G + S +++
Sbjct: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVS 1141
Query: 334 GLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDV-TAVNISATSLTLIWKVSDNE 392
GL PG Y T+ P + T ++ N LT+ W+ S
Sbjct: 1142 GLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP 1201
Query: 393 SSSNYTYKIHVAGETDSSNL----NVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFL 448
+ Y ++L + + L YN++V V D E P
Sbjct: 1202 DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD 1261
Query: 449 QVHTPPVPVSDFRVTVVSTTEIGLAWS---SHDAESFQMHITQEGAGNSRVEIT---TNQ 502
+ P +D R T + + + W+ S D +F + + E++ ++
Sbjct: 1262 TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDN 1321
Query: 503 SIIIGGLFPGTKYCFEI 519
++++ L PGT+Y +
Sbjct: 1322 AVVLTNLLPGTEYVVSV 1338
Score = 41.6 bits (96), Expect = 0.002
Identities = 80/339 (23%), Positives = 125/339 (36%), Gaps = 77/339 (22%)
Query: 111 QKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENE----KTITVV 166
Q PSS+GP VF + S P + + W + + KY+++ + +N K T+
Sbjct: 603 QTYPSSSGPVEVFITETPS-QPNSHPIQWNAPQPSHIS-KYILRWRPKNSVGRWKEATIP 660
Query: 167 -HQPWCNITGLRPATSYVFSITPGIGNETWGDPRVIK----------------VITEPIP 209
H I GL+P Y + I + +G V + V E P
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQL---ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
Query: 210 VSDLRVALTGVRKAA-----LSWSNGNGTAS-CRVLLESIGSHEELTQ----DSRLQVNI 259
S L V + +SW + + T S RV E +E + VNI
Sbjct: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNI 777
Query: 260 SGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAP----VHDESLV- 314
L PG +Y +N Y + + E L S ++ + +P P V D S+V
Sbjct: 778 PDLLPGRKYIVNVYQISED--------GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVV 829
Query: 315 ---GPVDPSSGQ--------QSRDTE---------VLLVGLEPGTRYNATVYSQAANGTE 354
P P +G + TE V L L+PG +YN T+Y+ N E
Sbjct: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN-QE 888
Query: 355 GQPQAIEFRTNAI-------QVFDVTAVNISATSLTLIW 386
P I+ T D+ V ++ +T++W
Sbjct: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW 927
Score = 40.4 bits (93), Expect = 0.004
Identities = 78/363 (21%), Positives = 130/363 (35%), Gaps = 36/363 (9%)
Query: 125 IKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQP---WCNITGLRPATS 181
++ + ++ + W + + + Y+ K T T P I GL+P
Sbjct: 1548 MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1607
Query: 182 YVFSITPGIGNETWGDPRVIKVITEPIPV-SDLRVALTGVRKAALSWSNGN-GTASCRVL 239
YV S+ N + +++ IP +DL+ + W+ N RV
Sbjct: 1608 YVVSVYAQ--NPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1665
Query: 240 L---ESIGSHEE--LTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLD-A 293
+ E G +E L DS V +SGL +Y ++ Y L+ T G L+
Sbjct: 1666 VTPKEKTGPMKEINLAPDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV 1724
Query: 294 SNTERSRAGSPTAPV-------HDESLVG-PVD--PSSGQQSRDTEV-------LLVGLE 336
S R+R T E++ G VD P++GQ + + GL+
Sbjct: 1725 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1784
Query: 337 PGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSN 396
PGT Y +Y+ N P I+ T ++ + + SL + W+ +
Sbjct: 1785 PGTDYKIYLYTLNDN-ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQ-PPRARITG 1842
Query: 397 YTYKIHVAGETDSSNLNVSEP---RAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTP 453
Y K G + P A I GL T Y I V + + + P + T
Sbjct: 1843 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTD 1902
Query: 454 PVP 456
+P
Sbjct: 1903 ELP 1905
Score = 33.1 bits (74), Expect = 0.66
Identities = 70/308 (22%), Positives = 108/308 (35%), Gaps = 41/308 (13%)
Query: 110 SQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQP 169
SQ T P P D + T++++ W + Y+ V +E T + +
Sbjct: 806 SQTTAPDAPPDPTVD----QVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPET 861
Query: 170 WCNIT--GLRPATSYVFSI---------TP-GIGNETWGDPRVIKVITEPIPVSDLRVAL 217
++T L+P Y +I TP I ET G PR T P P V +
Sbjct: 862 ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPR---SDTVPSPRDLQFVEV 918
Query: 218 TGVRKAALSWSNGNGTASCRVLLESI---GSHEELTQDSR-LQVNISGLKPGVQYNINPY 273
T V+ + + RV + + G H + SR ++GL PGV Y +
Sbjct: 919 TDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVF 978
Query: 274 ----------LLQSNKTKGD-PLGTEGGLDASNTERSRAGSPTAPVHDESL-VGPVDPSS 321
L TK D P + + +T R P A + L VG
Sbjct: 979 AVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
Query: 322 GQQ----SRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNI 377
+Q ++ L L+P + Y TV A G + P+A T + N
Sbjct: 1039 PRQYNVGPSVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
Query: 378 SATSLTLI 385
T T++
Sbjct: 1097 EVTETTIV 1104
>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
Length = 2176
Score = 63.5 bits (153), Expect = 5e-10
Identities = 94/384 (24%), Positives = 141/384 (36%), Gaps = 50/384 (13%)
Query: 173 ITGLRPATSYVFSITPGIGNETWGDPRVI--KVITEPIPVSDLRVALTGVRKAALSWSNG 230
+T L P T YV SI G E P +I + +P DL V +SW
Sbjct: 1415 LTNLTPGTEYVVSIVALNGREE--SPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAP 1471
Query: 231 NGTASC-RVLLESIGSHEELTQ----DSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPL 285
T R+ G + + + S+ ISGLKPGV Y I Y + +GD
Sbjct: 1472 AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG---RGDSP 1528
Query: 286 GTEGGLDAS-NTERSRAGS-PTAPVHDESLVGPVDPSSGQQS------------------ 325
+ + + TE + V D S+ PSS +
Sbjct: 1529 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588
Query: 326 ----RDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATS 381
TE+ + GL+P Y +VY+Q +G E QP T D+ ++ TS
Sbjct: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG-ESQPLVQTAVTTIPAPTDLKFTQVTPTS 1647
Query: 382 LTLIWKVSDNESSSNYTYKI---HVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVL 438
L+ W N + Y ++ G NL V+ GL +T Y ++V +
Sbjct: 1648 LSAQW-TPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1706
Query: 439 GDIEGTP--GFLQVHTPPVPVSDFRVTVVSTTEIGLAW--SSHDAESFQMHITQEGAGNS 494
+ P G + P RVT + T I ++W + FQ+ G +
Sbjct: 1707 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQT 1765
Query: 495 RVEITTN---QSIIIGGLFPGTKY 515
++ T +S I GL PGT Y
Sbjct: 1766 PIQRTIKPDVRSYTITGLQPGTDY 1789
Score = 61.2 bits (147), Expect = 2e-09
Identities = 71/306 (23%), Positives = 130/306 (42%), Gaps = 33/306 (10%)
Query: 244 GSHEELT-QDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEG---GLDASNTERS 299
GS EL ++ V +S L+PGVQYNI Y ++ N+ + P+ + G S+T S
Sbjct: 851 GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQ-ESTPVVIQQETTGTPRSDTVPS 909
Query: 300 RAGSPTAPVHDESL-----------------VGPVD--PSSGQQ---SRDTEVLLVGLEP 337
V D + V PV+ GQ+ SR+T + GL P
Sbjct: 910 PRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSP 969
Query: 338 GTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSS-N 396
G Y V++ ++G E +P + T ++ VN + +++ + W + +
Sbjct: 970 GVTYYFKVFA-VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYR 1028
Query: 397 YTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEG--TPGFLQVHTPP 454
T + G+ N+ S + + L+ ++ Y +++ + G+ E G P
Sbjct: 1029 LTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG 1088
Query: 455 VPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVEITTNQ-SIIIGGLFPGT 513
+ + V TT I + W+ F++ + G + E+T++ SI++ GL PG
Sbjct: 1089 SSIPPYNTEVTETT-IVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGV 1147
Query: 514 KYCFEI 519
+Y + I
Sbjct: 1148 EYVYTI 1153
Score = 58.5 bits (140), Expect = 1e-08
Identities = 100/467 (21%), Positives = 163/467 (34%), Gaps = 53/467 (11%)
Query: 110 SQKTPSSTG------PSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTI 163
+Q++P +TG P ++ T +++TW +K V+ E
Sbjct: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG--FKLGVRPSQGGEAPR 1129
Query: 164 TVVHQPWCNI-TGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVAL---TG 219
V + +GL P YV++I + P V KV+T P ++L + TG
Sbjct: 1130 EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTG 1189
Query: 220 VRKAALSWSNGNGTASCRVLL-----ESIGSHEELTQDSRLQVNISGLKPGVQYNINPYL 274
V + S R+ + S EE+ + L PG++YN++ Y
Sbjct: 1190 VLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
Query: 275 LQSNKTK--------------GDPLGTEGGLDASNTERSRAGS--------PTAPVHDES 312
++ +K D T G D + S +PV +E
Sbjct: 1250 VKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1309
Query: 313 LVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDV 372
V + S D V+L L PGT Y +V S E P +T +
Sbjct: 1310 DVAELSISPS----DNAVVLTNLLPGTEYVVSV-SSVYEQHESTPLRGRQKTGLDSPTGI 1364
Query: 373 TAVNISATSLTLIWKVSDNESSSNYT---YKIHVAGETDSSNLNVSEPRAVIPGLRSSTF 429
+I+A S T+ W ++ + + Y + H +G + S + L T
Sbjct: 1365 DFSDITANSFTVHW-IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
Query: 430 YNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQ- 488
Y +++ + G E Q T D V + T + ++W + IT
Sbjct: 1424 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG 1483
Query: 489 EGAGNSRVEITT----NQSIIIGGLFPGTKYCFEIVPKGPNGTEGAS 531
E GNS V+ T + I GL PG Y + G AS
Sbjct: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
Score = 51.2 bits (121), Expect = 2e-06
Identities = 87/383 (22%), Positives = 143/383 (37%), Gaps = 41/383 (10%)
Query: 173 ITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAAL--SWSNG 230
+ L+PA+ Y S+ GN+ P+ V T P S + T V + + +W+
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
Query: 231 NGTASCRVLLESIGSH--EELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDP---- 284
+ S G E+T DS + +SGL PGV+Y +L+ + + P
Sbjct: 1111 PRIGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNK 1169
Query: 285 ----------LGTEGGLDASNTERSRAGSPTAPVHDESLVGPVDPSSGQQSRDTEVLL-- 332
L E D S S T + + P++GQQ E ++
Sbjct: 1170 VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRIT--TTPTNGQQGNSLEEVVHA 1227
Query: 333 -------VGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLI 385
L PG YN +VY+ + E P + D+ NI ++ +
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYT-VKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVT 1286
Query: 386 WKVSDNESSSNYTYKIH-VAGETDSSNLNV--SEPRAVIPGLRSSTFYNITVCPVLGDIE 442
W + +N+ + V E D + L++ S+ V+ L T Y ++V V E
Sbjct: 1287 WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
Query: 443 GTPGFLQVHT---PPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVEIT 499
TP + T P + +T S T +A + H + +G R +
Sbjct: 1347 STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
Query: 500 --TNQSIIIGGLFPGTKYCFEIV 520
+ SI + L PGT+Y IV
Sbjct: 1407 PHSRNSITLTNLTPGTEYVVSIV 1429
Score = 49.7 bits (117), Expect = 7e-06
Identities = 47/208 (22%), Positives = 79/208 (37%), Gaps = 13/208 (6%)
Query: 325 SRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTL 384
S T V + L PG +Y VY + +G + + T D T + TS+ +
Sbjct: 770 STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVV 829
Query: 385 IWKVSDNESSS-NYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEG 443
W + Y V G + NL + + L+ YNIT+ V + E
Sbjct: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
Query: 444 TPGFLQVHTPPVPVS-------DFRVTVVSTTEIGLAWSSHDA-----ESFQMHITQEGA 491
TP +Q T P S D + V+ ++ + W+ ++ + + G
Sbjct: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
Query: 492 GNSRVEITTNQSIIIGGLFPGTKYCFEI 519
R+ I+ N + GL PG Y F++
Sbjct: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKV 977
Score = 46.2 bits (108), Expect = 8e-05
Identities = 77/366 (21%), Positives = 136/366 (37%), Gaps = 50/366 (13%)
Query: 101 QGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENE 160
Q +G +T +T P+P D+K ++PT++ W + + Y+ V K +
Sbjct: 1615 QNPSGESQPLVQTAVTTIPAPT-DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG 1673
Query: 161 KTITVVHQPWCN---ITGLRPATSYVFSITPGIGNETWGDPR--VIKVITEPIPVSDLRV 215
+ P + ++GL AT Y S+ + + P V+ + P RV
Sbjct: 1674 PMKEINLAPDSSSVVVSGLMVATKYEVSVY-ALKDTLTSRPAQGVVTTLENVSPPRRARV 1732
Query: 216 ALTGVRKAALSWSNGNGTASCRVLLESIGSHEELTQDSRLQVN-----ISGLKPGVQYNI 270
+SW T + ++++ ++ + ++ + I+GL+PG Y I
Sbjct: 1733 TDATETTITISWRTKTETIT-GFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1791
Query: 271 NPYLLQSNKTKGDPLGTEGG--LDASNTERSRAGSPTAPV----------------HDES 312
Y L N + P+ + +DA + R A +P + + +++
Sbjct: 1792 YLYTLNDN-ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKP 1850
Query: 313 LVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDV 372
P + + TE + GLEPGT Y T+Y A + I + +
Sbjct: 1851 GSPPREVVPRPRPGVTEATITGLEPGTEY--TIYVIALKNNQKSEPLIGRKKTGQEALSQ 1908
Query: 373 TAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEP----RAVIPGLRSST 428
T T+ W + + +S Y H G TD L P A + GL
Sbjct: 1909 T---------TISW--APFQDTSEYIISCHPVG-TDEEPLQFRVPGTSTSATLTGLTRGA 1956
Query: 429 FYNITV 434
YNI V
Sbjct: 1957 TYNIIV 1962
Score = 45.4 bits (106), Expect = 1e-04
Identities = 82/434 (18%), Positives = 157/434 (36%), Gaps = 39/434 (8%)
Query: 124 DIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENE--KTITVV-HQPWCNITGLRPAT 180
D++ V+ +PT+++++W + Y+ N + TV + I+GL+P
Sbjct: 1453 DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGV 1512
Query: 181 SY---VFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSW--SNGNGTAS 235
Y V+++T + P I TE S ++V ++ W S+ T
Sbjct: 1513 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGY 1572
Query: 236 CRVLLESIGSHEELTQDS---RLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEG--G 290
G T+ + + ++ I GL+P V+Y ++ Y Q+ + PL
Sbjct: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY-AQNPSGESQPLVQTAVTT 1631
Query: 291 LDASNTERSRAGSPTA-----------------PVHDESLVGPVDPSSGQQSRDTEVLLV 333
+ A + +PT+ V + GP+ + V++
Sbjct: 1632 IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM-KEINLAPDSSSVVVS 1690
Query: 334 GLEPGTRYNATVYSQAANGTEGQPQ-AIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNE 392
GL T+Y +VY+ T Q + N + + T++T+ W+
Sbjct: 1691 GLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET 1750
Query: 393 SSSNYTYKIHVAGETDSSNLNVSEPRA-VIPGLRSSTFYNITVCPVLGDIEGTPGFLQVH 451
+ + G+T + R+ I GL+ T Y I + + + +P +
Sbjct: 1751 ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1810
Query: 452 TPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVEITTN-----QSIII 506
T S+ R + + ++W A I E G+ E+ I
Sbjct: 1811 TAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 1870
Query: 507 GGLFPGTKYCFEIV 520
GL PGT+Y ++
Sbjct: 1871 TGLEPGTEYTIYVI 1884
Score = 42.7 bits (99), Expect = 8e-04
Identities = 77/437 (17%), Positives = 153/437 (35%), Gaps = 34/437 (7%)
Query: 115 SSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKY---VVKHKMENEKTITVVHQPWC 171
S T PSP D++ V ++ V + W ++A + Y+ V E+ + + + +
Sbjct: 904 SDTVPSPR-DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFA 962
Query: 172 NITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGN 231
+TGL P +Y F + + + P + T+ ++L+ + W+
Sbjct: 963 EVTGLSPGVTYYFKVF-AVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
Query: 232 GTASCRVLLESIGSHEELTQ----DSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGT 287
+ L + + Q S + + L+P +Y ++ ++ N+ G
Sbjct: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
Query: 288 ------EGGLDASNTE--RSRAGSPTAPVHDESLVGPVDPSSGQQ------SRDTEVLLV 333
+ NTE + P V PS G + S +++
Sbjct: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVS 1141
Query: 334 GLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDV-TAVNISATSLTLIWKVSDNE 392
GL PG Y T+ P + T ++ N LT+ W+ S
Sbjct: 1142 GLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP 1201
Query: 393 SSSNYTYKIHVAGETDSSNL----NVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFL 448
+ Y ++L + + L YN++V V D E P
Sbjct: 1202 DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD 1261
Query: 449 QVHTPPVPVSDFRVTVVSTTEIGLAWS---SHDAESFQMHITQEGAGNSRVEIT---TNQ 502
+ P +D R T + + + W+ S D +F + + E++ ++
Sbjct: 1262 TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDN 1321
Query: 503 SIIIGGLFPGTKYCFEI 519
++++ L PGT+Y +
Sbjct: 1322 AVVLTNLLPGTEYVVSV 1338
Score = 41.6 bits (96), Expect = 0.002
Identities = 80/339 (23%), Positives = 125/339 (36%), Gaps = 77/339 (22%)
Query: 111 QKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENE----KTITVV 166
Q PSS+GP VF + S P + + W + + KY+++ + +N K T+
Sbjct: 603 QTYPSSSGPVEVFITETPS-QPNSHPIQWNAPQPSHIS-KYILRWRPKNSVGRWKEATIP 660
Query: 167 -HQPWCNITGLRPATSYVFSITPGIGNETWGDPRVIK----------------VITEPIP 209
H I GL+P Y + I + +G V + V E P
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQL---ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
Query: 210 VSDLRVALTGVRKAA-----LSWSNGNGTAS-CRVLLESIGSHEELTQ----DSRLQVNI 259
S L V + +SW + + T S RV E +E + VNI
Sbjct: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNI 777
Query: 260 SGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAP----VHDESLV- 314
L PG +Y +N Y + + E L S ++ + +P P V D S+V
Sbjct: 778 PDLLPGRKYIVNVYQISED--------GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVV 829
Query: 315 ---GPVDPSSGQ--------QSRDTE---------VLLVGLEPGTRYNATVYSQAANGTE 354
P P +G + TE V L L+PG +YN T+Y+ N E
Sbjct: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN-QE 888
Query: 355 GQPQAIEFRTNAI-------QVFDVTAVNISATSLTLIW 386
P I+ T D+ V ++ +T++W
Sbjct: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW 927
Score = 40.0 bits (92), Expect = 0.005
Identities = 76/352 (21%), Positives = 126/352 (35%), Gaps = 36/352 (10%)
Query: 125 IKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQP---WCNITGLRPATS 181
++ + ++ + W + + + Y+ K T T P I GL+P
Sbjct: 1548 MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1607
Query: 182 YVFSITPGIGNETWGDPRVIKVITEPIPV-SDLRVALTGVRKAALSWSNGN-GTASCRVL 239
YV S+ N + +++ IP +DL+ + W+ N RV
Sbjct: 1608 YVVSVYAQ--NPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1665
Query: 240 L---ESIGSHEE--LTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLD-A 293
+ E G +E L DS V +SGL +Y ++ Y L+ T G L+
Sbjct: 1666 VTPKEKTGPMKEINLAPDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV 1724
Query: 294 SNTERSRAGSPTAPV-------HDESLVG-PVD--PSSGQQSRDTEV-------LLVGLE 336
S R+R T E++ G VD P++GQ + + GL+
Sbjct: 1725 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1784
Query: 337 PGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSN 396
PGT Y +Y+ N P I+ T ++ + + SL + W+ +
Sbjct: 1785 PGTDYKIYLYTLNDN-ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQ-PPRARITG 1842
Query: 397 YTYKIHVAGETDSSNLNVSEP---RAVIPGLRSSTFYNITVCPVLGDIEGTP 445
Y K G + P A I GL T Y I V + + + P
Sbjct: 1843 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1894
Score = 33.1 bits (74), Expect = 0.66
Identities = 70/308 (22%), Positives = 108/308 (35%), Gaps = 41/308 (13%)
Query: 110 SQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQP 169
SQ T P P D + T++++ W + Y+ V +E T + +
Sbjct: 806 SQTTAPDAPPDPTVD----QVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPET 861
Query: 170 WCNIT--GLRPATSYVFSI---------TP-GIGNETWGDPRVIKVITEPIPVSDLRVAL 217
++T L+P Y +I TP I ET G PR T P P V +
Sbjct: 862 ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPR---SDTVPSPRDLQFVEV 918
Query: 218 TGVRKAALSWSNGNGTASCRVLLESI---GSHEELTQDSR-LQVNISGLKPGVQYNINPY 273
T V+ + + RV + + G H + SR ++GL PGV Y +
Sbjct: 919 TDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVF 978
Query: 274 ----------LLQSNKTKGD-PLGTEGGLDASNTERSRAGSPTAPVHDESL-VGPVDPSS 321
L TK D P + + +T R P A + L VG
Sbjct: 979 AVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
Query: 322 GQQ----SRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNI 377
+Q ++ L L+P + Y TV A G + P+A T + N
Sbjct: 1039 PRQYNVGPSVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
Query: 378 SATSLTLI 385
T T++
Sbjct: 1097 EVTETTIV 1104
>gi|157384973 tenascin R [Homo sapiens]
Length = 1358
Score = 59.7 bits (143), Expect = 7e-09
Identities = 102/452 (22%), Positives = 173/452 (38%), Gaps = 49/452 (10%)
Query: 101 QGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENE 160
+G+N +D A+ T +T +++ S + T++ L W +++ EYK V +
Sbjct: 578 RGTNESDSAT--TQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQ 635
Query: 161 KTITVVHQ-----PWCNITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRV 215
+V + +T L P T Y I+ + N P + TE DL V
Sbjct: 636 YHEVLVPRGIGPTTRATLTDLVPGTEYGVGIS-AVMNSQQSVPATMNARTELDSPRDLMV 694
Query: 216 ALTGVRKAALSWSNGNGTASCR--VLLESIGSHEELT-QDSRLQVNISGLKPGVQYNINP 272
+ +L W+ +G S G E+T R ++ L+PG +Y
Sbjct: 695 TASSETSISLIWTKASGPIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEY---- 750
Query: 273 YLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAPVHDESL-VGPVDPSS-------GQQ 324
++ +G E +DA R + + V S+ + DPS
Sbjct: 751 -IISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYS 809
Query: 325 SRDTE--------------VLLVGLEPGTRYNATVYSQAANGT-EGQPQAIEFRTNAIQV 369
RD E +L+GL+P T Y + A +GT +P T
Sbjct: 810 PRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLV--AVHGTVTSEPIVGSITTGIDPP 867
Query: 370 FDVTAVNISATSLTLIWKVSDNESSSNY---TYKIHVAGETDSSNLNVSEPRAVIPGLRS 426
D+T N++ S+ + W S +S +Y +Y+ G DSS + + I L
Sbjct: 868 KDITISNVTKDSVMVSW--SPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNP 925
Query: 427 STFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSS--HDAESFQM 484
+T Y I++ V G E VHT D T ++ TE L W + + E++ +
Sbjct: 926 ATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENYVI 985
Query: 485 HITQEG-AGNSRVEITTNQSIIIGGLFPGTKY 515
+T AG + + ++ + L P T Y
Sbjct: 986 VLTHFAVAGETILVDGVSEEFRLVDLLPSTHY 1017
Score = 56.2 bits (134), Expect = 7e-08
Identities = 97/444 (21%), Positives = 154/444 (34%), Gaps = 48/444 (10%)
Query: 114 PSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITV---VHQPW 170
P + +P D++ IS ++ L W D + +YV+ ++ + + V W
Sbjct: 321 PDCSAVAPPEDLRVAGISDRSIELEW---DGPMAVTEYVISYQPTALGGLQLQQRVPGDW 377
Query: 171 CN--ITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWS 228
IT L P +Y S+ I N P KV T L+ + W
Sbjct: 378 SGVTITELEPGLTYNISVYAVISN-ILSLPITAKVATHLSTPQGLQFKTITETTVEVQWE 436
Query: 229 ----NGNGTASCRVLLESIGSHEELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDP 284
+ +G + + G N +GLKPG +Y +N L+ + + P
Sbjct: 437 PFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKE-QARSPP 495
Query: 285 LGTEGGL-----------DASNTERSRAGSPTAPVHDESLV--GPVDPSSGQ-----QSR 326
D S+T P D L+ G V G+ Q
Sbjct: 496 TSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPP 555
Query: 327 DTEVLLVGLEPGTRYNATVYSQAANGT-EGQPQAIEFRTNAIQVFDVTAVNISATSLTLI 385
++ + L PG+RY +V A GT E +F T ++ + +ATSL L
Sbjct: 556 LSQYSVQALRPGSRYEVSV--SAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLE 613
Query: 386 WKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAVIPGLRSS-------TFYNITVCPVL 438
W DN + YK+ + V PR + P R++ T Y + + V+
Sbjct: 614 W---DNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVM 670
Query: 439 GDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVEI 498
+ P + T D VT S T I L W+ IT + E+
Sbjct: 671 NSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIASEV 730
Query: 499 TT---NQSIIIGGLFPGTKYCFEI 519
T S + L PG +Y +
Sbjct: 731 TVPKDRTSYTLTDLEPGAEYIISV 754
Score = 33.5 bits (75), Expect = 0.51
Identities = 38/152 (25%), Positives = 62/152 (40%), Gaps = 7/152 (4%)
Query: 124 DIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITV--VHQPWCNITGLRPATS 181
D+ A +I+PT +L WK+ Y V+ H +TI V V + + + L P+T
Sbjct: 958 DLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEF-RLVDLLPSTH 1016
Query: 182 YVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNGTASCRVLL- 240
Y ++ G T G T P ++L + + A +SW VL
Sbjct: 1017 YTATMYATNGPLTSGTIST-NFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTY 1075
Query: 241 -ESIGSHEELTQDSR-LQVNISGLKPGVQYNI 270
+ GS +EL D+ + + GL Y +
Sbjct: 1076 KSTDGSRKELIVDAEDTWIRLEGLLENTDYTV 1107
>gi|62988324 tenascin N [Homo sapiens]
Length = 1299
Score = 59.7 bits (143), Expect = 7e-09
Identities = 95/461 (20%), Positives = 172/461 (37%), Gaps = 64/461 (13%)
Query: 100 EQGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSN---DTAASEYKYVVKHK 156
E+G G D A TP ++ + + +++++W+ + D Y Y + +
Sbjct: 251 EEGFTGLDCAQVVTPQG--------LQLLKNTEDSLLVSWEPSSQVDHYLLSY-YPLGKE 301
Query: 157 MENEKTITVVHQPWCNITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVA 216
+ ++ Q I GL P T Y+ ++ + NE P+ + T+ + V
Sbjct: 302 LSGKQIQVPKEQHSYEILGLLPGTKYIVTLR-NVKNEVSSSPQHLLATTDLAVLGTAWVT 360
Query: 217 LTGVRKAALSWSNGNGTASCRVLLESIGSHEELTQ-------DSRLQVNISGLKPGVQYN 269
+ W N + L + +E+ + D + + +I+GL PG +Y
Sbjct: 361 DETENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYK 420
Query: 270 INPYLLQSNKTKGDPLGTEGGLDA---SNTERSRAGSPTAPVHDESLVGPVDP------- 319
I ++ + +G P+ G + +N R TA V + + +D
Sbjct: 421 ITVVPMRG-ELEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTS 479
Query: 320 ------SSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFD-- 371
++ +L GL+PG Y VY A G +G +A TNA+ D
Sbjct: 480 ADGDTKEMAVHKDESSTVLTGLKPGEAYK--VYVWAERGNQGSKKA---DTNALTEIDSP 534
Query: 372 --VTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNV----SEPRAVIPGLR 425
+ ++ + T+ W D ++ Y + D V + V+ GLR
Sbjct: 535 ANLVTDRVTENTATISW---DPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLR 591
Query: 426 SSTFYNITVCPVLGDIEG----TPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDA-- 479
Y + V GD E T + +P V+D RVT T ++W A
Sbjct: 592 PGVEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTD-RVTENMAT---VSWDPVQAAI 647
Query: 480 ESFQMHITQEGAGNSRVEITTNQ-SIIIGGLFPGTKYCFEI 519
+ + + T G V + Q S ++ GL PG +Y +
Sbjct: 648 DKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHV 688
Score = 54.7 bits (130), Expect = 2e-07
Identities = 55/219 (25%), Positives = 94/219 (42%), Gaps = 24/219 (10%)
Query: 332 LVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDN 391
++GL PGT+Y T+ + N PQ + T+ + + + SL + W +N
Sbjct: 318 ILGLLPGTKYIVTLRN-VKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEW---EN 373
Query: 392 ESSSNYTYKIHVAGETDSSNLNVSEPRAVIP-------GLRSSTFYNITVCPVLGDIEGT 444
S+ YK+ T V+ P++ P GL T Y ITV P+ G++EG
Sbjct: 374 PSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGK 433
Query: 445 P----GFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMHITQEGAGNSRVEITT 500
P G ++ +P V+D RVT + T ++W A + + A E+
Sbjct: 434 PILLNGRTEIDSPTNVVTD-RVTEDTAT---VSWDPVQAVIDKYVVRYTSADGDTKEMAV 489
Query: 501 NQ---SIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCN 536
++ S ++ GL PG Y ++ G +G+ + N
Sbjct: 490 HKDESSTVLTGLKPGEAY--KVYVWAERGNQGSKKADTN 526
Score = 45.8 bits (107), Expect = 1e-04
Identities = 84/413 (20%), Positives = 150/413 (36%), Gaps = 32/413 (7%)
Query: 150 KYVVKHKMENEKTITVV---HQPWCNITGLRPATSYVFSITPGIGNETW--GDPRVIKVI 204
KYVV++ +T V Q +TGLRP Y+ + G++ D + I
Sbjct: 649 KYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDI 708
Query: 205 TEPIPVSDLRVALTGVRKAALSWSNGNGTASCRVLLESIGSHEELTQ----DSRLQVNIS 260
P + RV A +SW T V+ + E + + ++
Sbjct: 709 DSPQNLVTDRVT---ENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLT 765
Query: 261 GLKPGVQYNINPYLLQ-SNKTKGDPLGTEGGLDA-SNTERSRAGSPTAPVHDESLVGPVD 318
GL+PGV+Y ++ + + + ++K + +D+ N TA V + + +D
Sbjct: 766 GLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATID 825
Query: 319 ------PSSGQQSRDTEV-------LLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTN 365
S+ ++R+ V +L GL PG Y V++Q N E + + +T
Sbjct: 826 RYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGN-QESKKADTKAQTE 884
Query: 366 AIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAVIPGLR 425
++ ++ T+ W GET + V+ GLR
Sbjct: 885 IDGPKNLVTDWVTENMATVSWDPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLTGLR 944
Query: 426 SSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMH 485
Y + V G E + T P + R + V+ + L W+ A+
Sbjct: 945 PGMEYMVHVWAQKGAQESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYI 1004
Query: 486 ITQEGAGNSRVEI---TTNQSIIIGGLFPGTKYCFEIVP-KGPNGTEGASRTV 534
+T + + E+ +Q + GL G Y +V KG + S T+
Sbjct: 1005 LTYQFPDGTVKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTL 1057
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 50.4 bits (119), Expect = 4e-06
Identities = 92/478 (19%), Positives = 169/478 (35%), Gaps = 61/478 (12%)
Query: 99 PEQGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKME 158
P+ + T TP + ++ +P ++ L+W + + ++
Sbjct: 3038 PKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDG 3097
Query: 159 NEKTITVV-HQPWCNITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPIP-------- 209
K + V H+ I+GL P Y ++ G + G I V E P
Sbjct: 3098 QPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTE 3157
Query: 210 ---------VSDLRVALTGVRKAALSWSNGNGT-ASCRVLLESIGSHEEL--TQDSRLQV 257
+ +L V + +LSW+ G S V + ++ + +V
Sbjct: 3158 APEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEV 3217
Query: 258 NISGLKPGVQYNINPYLLQSNKTKG--DPLGTEGGLDASNTERSRAGS-PTAPVHDESL- 313
+ GL+PG +Y ++ Y L + G +G L R G A V +S+
Sbjct: 3218 TVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVG 3277
Query: 314 ------VGPVD------------PSSGQQSRDTEVLLV-GLEPGTRYNATVYSQAANGTE 354
GP D P + S D + V GL+P +Y ++ NG
Sbjct: 3278 LSWTVAQGPFDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFG-LQNGKR 3336
Query: 355 GQPQAIEFRT-----NAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDS 409
P +E RT + ++ ++T + + S+ L W V + E S G
Sbjct: 3337 HGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQV 3396
Query: 410 SNLNVSEPRAVIPGLRSSTFYNITVCPVLG-------DIEGTPGFLQVHTPPVPVSDFRV 462
+ ++ + GL S Y + + G + T L+ PP + + V
Sbjct: 3397 VPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPP-HLGELTV 3455
Query: 463 TVVSTTEIGLAWSSHDA--ESFQMHITQEGAGNSRVEITTNQ-SIIIGGLFPGTKYCF 517
+++ + L+W+ +SF + V + +Q ++ + L PG KY F
Sbjct: 3456 AEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKF 3513
Score = 45.4 bits (106), Expect = 1e-04
Identities = 101/520 (19%), Positives = 177/520 (34%), Gaps = 90/520 (17%)
Query: 86 DGESSGANDSLRTPEQGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSNDTA 145
+G G ++ E + T TP + ++ +P ++ L+W +
Sbjct: 2809 EGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQ 2868
Query: 146 ASEYKYVVKHKMENEKTITVV-HQPWCNITGLRPATSYVFSITPGIGNETWGDPRVIKVI 204
+ ++ K + V H+ I+GL P Y ++ G + G VI V
Sbjct: 2869 FDHFLVQYRNGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVT 2928
Query: 205 ---------TEPIP----------VSDLRVALTGVRKAALSWSNGNGTA-SCRVLLESIG 244
TEP + +L V + +LSW+ G S V +
Sbjct: 2929 AAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRD 2988
Query: 245 SHEELTQ--DSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGL----DASNTER 298
++ + +V + GL+PG +Y ++ Y L + G P+ G +A T+
Sbjct: 2989 GRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVG-PVSAVGVTAPKDEAETTQA 3047
Query: 299 SRAGSPTAPVH---DESLVGPVDPSS---------GQ--------------------QSR 326
+P P+ E V P S GQ
Sbjct: 3048 VPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGH 3107
Query: 327 DTEVLLVGLEPGTRYNATVYS----------QAANGTEGQ-PQAIEFRTNAIQ------V 369
+ V + GLEP +Y +Y A TE + P E T A + +
Sbjct: 3108 EDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLL 3167
Query: 370 FDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTF 429
++T S SL+L W V S G+ + E + GL
Sbjct: 3168 GELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRK 3227
Query: 430 YNITVCPV-----LGDIEGTPGFLQVHTPPVPV----SDFRVTVVSTTEIGLAWSSHDA- 479
Y + + + +G + T G P+PV + V V++ +GL+W+
Sbjct: 3228 YKMHLYGLHEGQRVGPV-STVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGP 3286
Query: 480 -ESFQMHITQEGAGNSRVEITTN-QSIIIGGLFPGTKYCF 517
+SF + V ++ + +++ + GL P KY F
Sbjct: 3287 FDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYKF 3326
Score = 41.6 bits (96), Expect = 0.002
Identities = 92/372 (24%), Positives = 136/372 (36%), Gaps = 80/372 (21%)
Query: 225 LSWSNGNGTASCRVLL--ESIGSHEELTQDS-RLQVNISGLKPGVQYNINPYLLQSNKTK 281
LSWS G V+ ++ G + L D + ++ ISGL+P Y Y L K
Sbjct: 3572 LSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRL 3631
Query: 282 GDPLGTEG--GLDASN--TERSRAGSPTAPVHD----------ESLVGPVD--------P 319
G PL EG GL + +E SR V D E+ G D P
Sbjct: 3632 G-PLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVP 3690
Query: 320 SSGQQSRDTEVLLVG--LEPGTRYNA--------TVYSQAANGTEGQPQAIEFRTNAIQV 369
S LL + PGTR++A T+YS G G +A + A +
Sbjct: 3691 SPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTL 3750
Query: 370 F-------DVTAVNISATSLTLIWKVSDNESSS-NYTYKIHVAGETDSSNLNVSEPRAVI 421
D+ I TS + W + + S +Y++ GE S ++ +
Sbjct: 3751 SPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKL 3810
Query: 422 PGLRSSTFYNITVCPVLGDIEGTP--GFLQVHTPPVPVSDFRVTVVSTTE--IGLAWS-- 475
GL Y +TV V G E P GFL VP ++ ++ TE L W
Sbjct: 3811 QGLIPGARYEVTVVSVRGFEESEPLTGFLTT----VPDGPTQLRALNLTEGFAVLHWKPP 3866
Query: 476 SHDAESFQMHITQEGAGNSRVE--------------ITTNQSIIIGGLFPGTKYCFEIVP 521
+ +++ + +T GA + E + TN + + GL
Sbjct: 3867 QNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGL------------ 3914
Query: 522 KGPNGTEGASRT 533
+GPN T AS T
Sbjct: 3915 RGPNLTSPASIT 3926
Score = 40.4 bits (93), Expect = 0.004
Identities = 97/495 (19%), Positives = 169/495 (34%), Gaps = 105/495 (21%)
Query: 124 DIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVV-HQPWCNITGLRPATSY 182
++ +P ++ L+W + + K+ K V H+ I+GL P Y
Sbjct: 2308 ELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKY 2367
Query: 183 VFSITPGIGNETWGDPRVIKVI---------TEPIP----------VSDLRVALTGVRKA 223
++ G + G I V TEP + +L V +
Sbjct: 2368 KMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSL 2427
Query: 224 ALSWSNGNGTA-SCRVLLESIGSHEELTQ--DSRLQVNISGLKPGVQYNINPYLLQSNKT 280
+LSW+ G S V + ++ + +V + GL+PG +Y ++ Y L +
Sbjct: 2428 SLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRR 2487
Query: 281 KGDPLGTEGGLDASNTERSRAGSPTAP------VHDESLVGPV-----DPSSGQQS---- 325
G P+ T G + A + SPT P +E L+G + P S S
Sbjct: 2488 VG-PVSTVG-VTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVP 2545
Query: 326 -------------------------RDTEVLLVGLEPGTRYNATVY-------------- 346
++++V + GLEPG +Y +Y
Sbjct: 2546 QGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAV 2605
Query: 347 ---SQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHV 403
A T+ P ++ ++T + + SL+L W V + + +
Sbjct: 2606 GVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQYRNG 2665
Query: 404 AGETDSSNLNVSEPRAVIPGLRSSTFYN--------------ITVCPVLGDIEGTPGFLQ 449
G+ + + E I GL Y I+V V E TP +
Sbjct: 2666 DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTE 2725
Query: 450 VHT-PPVP-----VSDFRVTVVSTTEIGLAWSSHDA--ESFQMHITQEGAGNSRVEITTN 501
+ T P P + + VT S + L+W+ +SF + + +
Sbjct: 2726 LSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMRVRGE 2785
Query: 502 QS-IIIGGLFPGTKY 515
+S + +GGL PG KY
Sbjct: 2786 ESEVTVGGLEPGRKY 2800
Score = 39.7 bits (91), Expect = 0.007
Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 7/109 (6%)
Query: 410 SNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTE 469
S+ + + R + PG Y +TV + G G P + T D RV V+ T
Sbjct: 800 SSASAYDQRGLAPGQE----YQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTT 855
Query: 470 IGLAWSSHDAESFQMHITQEGAGNSRVEITT---NQSIIIGGLFPGTKY 515
+ L W AE + ++ AGN RV + ++ L PG +Y
Sbjct: 856 LELGWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEY 904
Score = 38.9 bits (89), Expect = 0.012
Identities = 69/330 (20%), Positives = 114/330 (34%), Gaps = 73/330 (22%)
Query: 257 VNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDA-----SNTERSRAGSPTA--PVH 309
V ISGL+P +Y +N Y + G P+ G A S TE S A P+
Sbjct: 2040 VTISGLEPDHKYKMNLYGFHGGQRMG-PVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLL 2098
Query: 310 DESLVGPVDPSSGQQS-----------------------------RDTEVLLVGLEPGTR 340
E V P S S ++EV + GLEPG +
Sbjct: 2099 GELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRK 2158
Query: 341 YNATVYS----------QAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSD 390
Y +Y A T + ++ + +++ +T +I++ SL+L W V +
Sbjct: 2159 YKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPE 2218
Query: 391 NESSSNYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLG----------- 439
+ + G+ + + E I GL Y + + G
Sbjct: 2219 GQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVG 2278
Query: 440 ------DIEGTPGFLQVHTPPVPV----SDFRVTVVSTTEIGLAWSSHDAESFQMHITQE 489
D E P + TP P+ + VT + + L+W+ + + F + Q
Sbjct: 2279 LTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQ-FDHFLVQY 2337
Query: 490 GAGNSRVEITT----NQSIIIGGLFPGTKY 515
G+ + + T + I GL P KY
Sbjct: 2338 KNGDGQPKATRVPGHEDRVTISGLEPDNKY 2367
Score = 38.9 bits (89), Expect = 0.012
Identities = 74/335 (22%), Positives = 111/335 (33%), Gaps = 77/335 (22%)
Query: 257 VNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDA-----SNTERSRAGS--PTAPVH 309
V ISGL+P +Y +N Y + G P+ G A S TE S P P+
Sbjct: 2681 VTISGLEPDHKYKMNLYGFHGGQRVG-PISVIGVTAAEEETPSPTELSTEAPEPPEEPLL 2739
Query: 310 DESLVGPVDPSSGQQS-----------------------------RDTEVLLVGLEPGTR 340
E V P S S ++EV + GLEPG +
Sbjct: 2740 GELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRK 2799
Query: 341 YNATVY-----------------SQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLT 383
Y +Y A T+ P N ++ ++T + + SL+
Sbjct: 2800 YKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLS 2859
Query: 384 LIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYN------------ 431
L W V + + + G+ + E I GL Y
Sbjct: 2860 LSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRV 2919
Query: 432 --ITVCPVLGDIEGTPGFLQVHT-PPVP-----VSDFRVTVVSTTEIGLAWSSHDA--ES 481
I+V V E TP + T P P + + VT S + L+W+ +S
Sbjct: 2920 GPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDS 2979
Query: 482 FQMHITQEGAGNSRVEITTNQS-IIIGGLFPGTKY 515
F + V + +S + +GGL PG KY
Sbjct: 2980 FTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCKY 3014
Score = 37.4 bits (85), Expect = 0.035
Identities = 107/529 (20%), Positives = 171/529 (32%), Gaps = 131/529 (24%)
Query: 105 GTDGASQKTPSSTGPS---------PVF-DIKAVSISPTNVILTWKSNDTAASEYKYVVK 154
G A ++TPS T PS P+ ++ SP ++ L+W + K
Sbjct: 2071 GVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYK 2130
Query: 155 HKMENEKTITVV-HQPWCNITGLRPATSYVFSITPGIGNETWGDPRVIKVITEP------ 207
+ + + V + + GL P Y + G+ P +T P
Sbjct: 2131 DRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLY-GLHEGRRVGPVSAVGVTAPEEESPD 2189
Query: 208 IPVSDLRVALTGVR-----KAALSWS--------------NGNGTASCRVLLESIGSHEE 248
P++ LR+ VR +LSW+ NG+G + HE+
Sbjct: 2190 APLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKA----VRVPGHED 2245
Query: 249 LTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKG-------DPLGTEGGLDASNTERSRA 301
V ISGL+P +Y +N Y + G G + + ++TE
Sbjct: 2246 -------GVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTP 2298
Query: 302 GSPTAPVHDESLVGPVDPSS---------GQ--------------------QSRDTEVLL 332
P P +E V P S GQ + V +
Sbjct: 2299 EPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTI 2358
Query: 333 VGLEPGTRYNATVY--------------------SQAANGTEGQPQAIEFRTNAIQVFDV 372
GLEP +Y +Y + + TE +A E + + ++
Sbjct: 2359 SGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPL-LGEL 2417
Query: 373 TAVNISATSLTLIWKVSDNE-SSSNYTYK--------IHVAGETDSSNLNVSEP------ 417
T S SL+L W V S YK + V GE + EP
Sbjct: 2418 TVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKM 2477
Query: 418 --RAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHT----PPVP--VSDFRVTVVSTTE 469
+ G R + V D++ TP + T PP + + VT S
Sbjct: 2478 HLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDS 2537
Query: 470 IGLAWSSHDA--ESFQMHITQEGAGNSRVEITTNQS-IIIGGLFPGTKY 515
+ L+W+ +SF + V + +S + + GL PG KY
Sbjct: 2538 LSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKY 2586
Score = 35.0 bits (79), Expect = 0.17
Identities = 47/221 (21%), Positives = 81/221 (36%), Gaps = 41/221 (18%)
Query: 335 LEPGTRYNATVYSQA---------ANGTEG-----QPQAIEFRTNAIQVFDVTAVNISAT 380
L+P +Y T++ A A+GT +P EF + + ++T ++
Sbjct: 1217 LDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPL-LGELTVTGVTPD 1275
Query: 381 SLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLG- 439
SL L W V+ S G+ + + E +PGL Y + + + G
Sbjct: 1276 SLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGR 1335
Query: 440 ----------------DIEGTPGFLQVHT--PPVP----VSDFRVTVVSTTEIGLAWS-- 475
D++ TP ++ T P P + + VT S + L W+
Sbjct: 1336 QRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVP 1395
Query: 476 SHDAESFQMHITQEGAGNSRVEITTNQS-IIIGGLFPGTKY 515
+SF + V + +S + +GGL PG KY
Sbjct: 1396 QGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKY 1436
Score = 33.9 bits (76), Expect = 0.39
Identities = 43/224 (19%), Positives = 81/224 (36%), Gaps = 33/224 (14%)
Query: 326 RDTEVLLVGLEPGTRYNATVY--------------SQAANGTEGQPQAIEFRTNAIQVFD 371
+++EV + GLEPG +Y +Y A E P A E ++ +
Sbjct: 1421 KESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEP-RLGE 1479
Query: 372 VTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYN 431
+T +++ S+ L W V + + S G+ + + + L Y
Sbjct: 1480 LTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYK 1539
Query: 432 ITVCPVLGDIEGTPGFLQVHTPPVP---------------VSDFRVTVVSTTEIGLAWSS 476
+ + + P + + T P+P + + VT ++ +GL+W+
Sbjct: 1540 MNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTV 1599
Query: 477 HDAE--SFQMHITQEGAGNSRVEITTNQ-SIIIGGLFPGTKYCF 517
+ E SF + V + +Q + I L P KY F
Sbjct: 1600 PEGEFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYKF 1643
Score = 30.8 bits (68), Expect = 3.3
Identities = 47/194 (24%), Positives = 67/194 (34%), Gaps = 18/194 (9%)
Query: 332 LVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDN 391
L GL PG RY TV S E +P T + A+N++ L WK N
Sbjct: 3810 LQGLIPGARYEVTVVS-VRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQN 3868
Query: 392 ESSSNYTYKIHVAGETDSSNLNVSEPRAVIP----GLRSSTFYNITVCPVLGDIEGTPGF 447
TY + V + L P + + L T Y TV + G +P
Sbjct: 3869 PVD---TYDVQVTA-PGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPAS 3924
Query: 448 LQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAE--SFQMHITQEGAGNSRV----EITTN 501
+ T D V+ L W+ + + G N + IT++
Sbjct: 3925 ITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSH 3984
Query: 502 QSIIIGGLFPGTKY 515
Q + GLFP T Y
Sbjct: 3985 QLL---GLFPSTSY 3995
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 46.2 bits (108), Expect = 8e-05
Identities = 57/224 (25%), Positives = 88/224 (39%), Gaps = 21/224 (9%)
Query: 328 TEVLLVGLEPGTRYNATVYS----QAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLT 383
T++ L GL P T Y TVY+ +A++ GQ + ++ N+ + S
Sbjct: 497 TDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPR----NLRISNVGSNSAR 552
Query: 384 LIWKVSDNESSSNYTYKIHVAGETDSSNLNVSE--PRAVIP--GLRSSTFYNITVCPVLG 439
L W D S Y+I V D + +N E P P GL T Y I + +
Sbjct: 553 LTW---DPTSRQINGYRI-VYNNADGTEINEVEVDPITTFPLKGLTPLTEYTIAIFSIYD 608
Query: 440 DIEGTPGFLQVHTPPVPVSDF-RVTVVSTTEIGLAW---SSHDAESFQMHITQEGAGNSR 495
+ + P T VP + + V+T + W S+ + M I G
Sbjct: 609 EGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEE 668
Query: 496 VEITTNQ-SIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRT 538
V + Q S +I GL PGT+Y ++ +G+E T T
Sbjct: 669 VVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTT 712
Score = 42.4 bits (98), Expect = 0.001
Identities = 70/334 (20%), Positives = 122/334 (36%), Gaps = 51/334 (15%)
Query: 158 ENEKTITVVHQPWCNITGLRPATSYVFSITPGIGNETWGDPRVIKVITEPI-PVSDLRVA 216
E E I H ++GL P T Y ++ G E DP + T + P +LR++
Sbjct: 487 EKEMKIGETHTD-IELSGLLPNTEYTVTVYAMFGEEA-SDPVTGQETTLALSPPRNLRIS 544
Query: 217 LTGVRKAALSWS-NGNGTASCRVLLESIGSHE--ELTQDSRLQVNISGLKPGVQYNINPY 273
G A L+W R++ + E E+ D + GL P +Y I +
Sbjct: 545 NVGSNSARLTWDPTSRQINGYRIVYNNADGTEINEVEVDPITTFPLKGLTPLTEYTIAIF 604
Query: 274 LLQSN----------KTKGDPLGTEGGLDASNTERSRAG----SPTAPVHDESLV----G 315
+ T+ P +D T+ R S +H + G
Sbjct: 605 SIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGG 664
Query: 316 PVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQ----------------PQA 359
+ ++ +D+ V+ GLEPGT Y ++ + +G+E +
Sbjct: 665 KTEEVVLKEEQDSHVI-EGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATT 723
Query: 360 IEFRTNAIQVFDVTAVNI-----SATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNV 414
I T+ VF N+ + +SL + W +SD++ + G+ + +
Sbjct: 724 IVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGT 783
Query: 415 -----SEPRAVIPGLRSSTFYNITVCPVLGDIEG 443
S+ ++ L T Y +TV P+ D EG
Sbjct: 784 VMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEG 817
Score = 35.8 bits (81), Expect = 0.10
Identities = 28/127 (22%), Positives = 54/127 (42%), Gaps = 1/127 (0%)
Query: 330 VLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVS 389
+L+ L G YN +++ A+G + +T + V ++ A ++ TSL W+V
Sbjct: 884 ILITNLLSGMDYNVKIFASQASGFSDALTGM-VKTLFLGVTNLQAKHVEMTSLCAHWQVH 942
Query: 390 DNESSSNYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQ 449
+ ++ + + S + R GL+ + Y I+V L +IEG +
Sbjct: 943 RHATAYRVVIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEGPSVSIM 1002
Query: 450 VHTPPVP 456
T +P
Sbjct: 1003 EKTQSLP 1009
Score = 33.1 bits (74), Expect = 0.66
Identities = 39/199 (19%), Positives = 76/199 (38%), Gaps = 7/199 (3%)
Query: 328 TEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWK 387
+ +L L T Y V++ A+ + E D+ +++ S+ + W
Sbjct: 405 SSTVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWD 464
Query: 388 VSDNESSSNYTYKI---HVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGT 444
S Y +AG+ + + + GL +T Y +TV + G+
Sbjct: 465 AVPGASGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASD 524
Query: 445 PGFLQVHTPPV-PVSDFRVTVVSTTEIGLAW--SSHDAESFQ-MHITQEGAGNSRVEITT 500
P Q T + P + R++ V + L W +S ++ ++ +G + VE+
Sbjct: 525 PVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTEINEVEVDP 584
Query: 501 NQSIIIGGLFPGTKYCFEI 519
+ + GL P T+Y I
Sbjct: 585 ITTFPLKGLTPLTEYTIAI 603
>gi|157311649 neogenin homolog 1 [Homo sapiens]
Length = 1461
Score = 45.8 bits (107), Expect = 1e-04
Identities = 108/508 (21%), Positives = 179/508 (35%), Gaps = 92/508 (18%)
Query: 64 TAESFHKQNGTGTPQVETNTSEDGESSGANDSL--------RTPEQGSNGTDGAS----- 110
T F+ + G +VE NTS GE +L R Q +G+ +S
Sbjct: 472 TYSVFYTKEGIARERVE-NTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRV 530
Query: 111 QKTPSSTGPSPVFDIKAVSISPTNVILTWK---SNDTAASEYK-YVVKHKMENEKTITVV 166
+ P P P +++A + SPT++ +TW+ S + YK Y ++ + E+ + V
Sbjct: 531 ETQPEVQLPGPAPNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDVDVS 590
Query: 167 HQPWCNITGLRPATSYVFSI-----------TPGIGNETWGDPRVIKVITEPIPVSDLRV 215
+ I GL+ T Y F + TP + T D + V + +
Sbjct: 591 SHSY-TINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKS 649
Query: 216 ALTGVRKAALSWSNGNGTA---SCRVLLESIGSHEELTQDSRLQVNISGLKPGVQYNINP 272
+ + A + NG T R E L ++L I GL G +YN
Sbjct: 650 IMIHWQPPAPATQNGQITGYKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRV 709
Query: 273 YLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAPVHDESLVGPVDPSSGQQSRDTEVLL 332
L N GT D + E + DE+ V P PSS ++
Sbjct: 710 AALTIN-------GTGPATDWLSAETFESDL------DETRV-PEVPSSLHVRPLVTSIV 755
Query: 333 VGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATS-LTLIWKVSDN 391
V P N V A G P A + + Q + T N+ +S + K +N
Sbjct: 756 VSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRY-YTIENLDPSSHYVITLKAFNN 814
Query: 392 ESSSNYTYKIHVA-GETDSSNLN---VSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGF 447
Y+ V TD+S ++ ++ P +P
Sbjct: 815 VGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPD------------------------ 850
Query: 448 LQVHTPPVPVSDFRVTVVSTTEIGLAWSSH---------DAESFQMHITQEGAGNSRVE- 497
TP +P + +++S I + W+ + D+ + + N++ +
Sbjct: 851 ---PTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKN 907
Query: 498 -ITTNQSIIIGGLFPGTKYCFEI-VPKG 523
T S ++ GL P T Y F + V KG
Sbjct: 908 ANATTLSYLVTGLKPNTLYEFSVMVTKG 935
Score = 41.2 bits (95), Expect = 0.002
Identities = 61/234 (26%), Positives = 91/234 (38%), Gaps = 36/234 (15%)
Query: 327 DTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISA-----TS 381
+ +V + L P T Y V +Q +G+ + T A N+ A TS
Sbjct: 495 EMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTS 554
Query: 382 LTLIWK--VSDNESSSNYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLG 439
+T+ W+ VS N NY G +++VS I GL+ T Y+ V V
Sbjct: 555 ITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRV--VAY 612
Query: 440 DIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQMH------ITQEGA-- 491
+ G PG V TP V V V S L+ +++S +H TQ G
Sbjct: 613 NKHG-PG---VSTPDVAVRTLS-DVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQIT 667
Query: 492 --------GNSRVEIT------TNQSIIIGGLFPGTKYCFEIVPKGPNGTEGAS 531
+ + ++T T S +I GL GT+Y F + NGT A+
Sbjct: 668 GYKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPAT 721
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 45.1 bits (105), Expect = 2e-04
Identities = 51/202 (25%), Positives = 83/202 (41%), Gaps = 21/202 (10%)
Query: 101 QGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSN--DTAASEYKYVVKHKME 158
+ S+GT A PSP ++K I+ +V +TW+ D + Y+V+ +
Sbjct: 23016 ENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREA 23075
Query: 159 NEKT----ITVVHQPWCNITGLRPATSYVFSITP----GIG-NETWGDPRVIKVITEPIP 209
K+ +T H+ I L+ SY F +T GIG DP IKV P P
Sbjct: 23076 TRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADP--IKVAEVPQP 23133
Query: 210 VSDLRVALTGVRKAALSWS---NGNGTASCRVLLESIGSHEELTQD----SRLQVNISGL 262
+ V +LSW+ + G+ + ++E H E + LQ I+ L
Sbjct: 23134 PGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNL 23193
Query: 263 KPGVQYNINPYLLQSNKTKGDP 284
G +Y + + + K + DP
Sbjct: 23194 TQGEEY-LFRVVAVNEKGRSDP 23214
Score = 42.4 bits (98), Expect = 0.001
Identities = 41/171 (23%), Positives = 69/171 (40%), Gaps = 21/171 (12%)
Query: 119 PSPVFDIKAVSISPTNVILTW--KSNDTAASEYKYVVKHKMENEKTITV----VHQPWCN 172
P PV D+K ++ T+ ++W ND + Y+V+ + + KT + V + +
Sbjct: 18699 PGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFH 18758
Query: 173 ITGLRPATSYVFSIT------PGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALS 226
+T L P Y F +T PG+ + ++EP P L V A L+
Sbjct: 18759 VTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLA 18818
Query: 227 W--SNGNGTASCRVLLESIGSHE-------ELTQDSRLQVNISGLKPGVQY 268
W +G A + S E E + L + ++GLK G +Y
Sbjct: 18819 WLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKY 18869
Score = 39.7 bits (91), Expect = 0.007
Identities = 45/203 (22%), Positives = 77/203 (37%), Gaps = 23/203 (11%)
Query: 101 QGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSN--DTAASEYKYVVKHKME 158
+ S+G+ A P P D+K ++ T+V LTW D + Y+V+ +
Sbjct: 21934 ENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRES 21993
Query: 159 NEKTITVV----HQPWCNITGLRPATSYVFSITP------GIGNETWGDPRVIKVITEPI 208
K + V H+ + L+ SY F + G+ ET +K P+
Sbjct: 21994 TRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAET---AESVKASERPL 22050
Query: 209 PVSDLRVALTGVRKAALSWSNGNGTASCRVL-----LESIGSHEELT--QDSRLQVNISG 261
P + + +LSW R+L +++ GS + T + I+G
Sbjct: 22051 PPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITG 22110
Query: 262 LKPGVQYNINPYLLQSNKTKGDP 284
L G +Y+ Q+ K DP
Sbjct: 22111 LIQGEEYSFR-VSAQNEKGISDP 22132
Score = 35.8 bits (81), Expect = 0.10
Identities = 39/168 (23%), Positives = 65/168 (38%), Gaps = 21/168 (12%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSN--DTAASEYKYVVKHKMENEKTITVVHQPWCNITGL 176
P P ++ IS + +TW+ D + YVV+ + K+ + V C+ T
Sbjct: 19787 PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTE-CSKTSF 19845
Query: 177 RPAT-----SYVFSITP----GIGNETWGDPR-VIKVITEPIPVSDLRVALTGVRKAALS 226
R A SY F + GIG+ G+ R +K P PV DL+V ++
Sbjct: 19846 RVANLEEGKSYFFRVFAENEYGIGDP--GETRDAVKASQTPGPVVDLKVRSVSKSSCSIG 19903
Query: 227 WSNGNGTASCRVL------LESIGSHEELTQDSRLQVNISGLKPGVQY 268
W + R++ L + + + LQ + L G +Y
Sbjct: 19904 WKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEY 19951
Score = 33.1 bits (74), Expect = 0.66
Identities = 30/114 (26%), Positives = 43/114 (37%), Gaps = 14/114 (12%)
Query: 376 NISATSLTLIWKVSDNESSSNYTYKIHVAGETDS-------SNLNVSEPRAVIPGLRSST 428
NI+ S+TL W +++ S I E S S +SE R + GL
Sbjct: 28162 NITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGN 28221
Query: 429 FYNITVCPV----LGDIEGTPGFLQVH---TPPVPVSDFRVTVVSTTEIGLAWS 475
Y V +G G ++ PP P + +VT S T + L WS
Sbjct: 28222 EYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWS 28275
Score = 32.3 bits (72), Expect = 1.1
Identities = 41/169 (24%), Positives = 67/169 (39%), Gaps = 20/169 (11%)
Query: 119 PSPVFDIKAVSISPTNVILTWK--SNDTAASEYKYVVKHK---MENEKTITV-VHQPWCN 172
P P +K +S +V +TW+ + D A Y+V+ + M KT+T +
Sbjct: 29538 PGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYR 29597
Query: 173 ITGLRPATSYVFSITP----GIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWS 228
I+GL T Y F + P GIG E + V P+ + L V L+W
Sbjct: 29598 ISGLVEGTMYYFRVLPENIYGIG-EPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWE 29656
Query: 229 N---GNGTASCRVLLESIGSHEE------LTQDSRLQVNISGLKPGVQY 268
G+ +LE+ + E + + L+ ++ L G QY
Sbjct: 29657 KPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQY 29705
Score = 31.6 bits (70), Expect = 1.9
Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Query: 453 PPVPVSDFRVTVVSTTEIGLAWSSHDAE------SFQMHITQEGAGN-SRVEITTNQSII 505
PP P D V TE+ L W+ D + + + +EG + + + TN +
Sbjct: 17409 PPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECV 17468
Query: 506 IGGLFPGTKYCFEI 519
+ GL G Y F +
Sbjct: 17469 VTGLQQGKTYRFRV 17482
Score = 31.6 bits (70), Expect = 1.9
Identities = 28/119 (23%), Positives = 45/119 (37%), Gaps = 11/119 (9%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSN--DTAASEYKYVVKHKMENEKT----ITVVHQPWCN 172
P PV +++ I+ +V L W D + Y+V+ + K+ T H+
Sbjct: 20868 PGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYK 20927
Query: 173 ITGLRPATSYVFSITP----GIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSW 227
+TGL Y F + GIG T +K P P L + +L+W
Sbjct: 20928 VTGLSEGCEYFFRVMAENEYGIGEPT-ETTEPVKASEAPSPPDSLNIMDITKSTVSLAW 20985
Score = 29.6 bits (65), Expect = 7.3
Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 5/89 (5%)
Query: 103 SNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKS-NDTAASEYK-YVVKH---KM 157
S G+ A+ + P PV D+K V + +L W D SE ++++ KM
Sbjct: 15181 SCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKM 15240
Query: 158 ENEKTITVVHQPWCNITGLRPATSYVFSI 186
+ + C+ITGL Y F +
Sbjct: 15241 HTWRQPIETERSKCDITGLLEGQEYKFRV 15269
Score = 29.6 bits (65), Expect = 7.3
Identities = 21/76 (27%), Positives = 34/76 (44%), Gaps = 11/76 (14%)
Query: 119 PSPVFDIKAVSISPTNVILTWK--SNDTAASEYKYVVKHKMENE------KTITVVHQPW 170
P P D+ V + T V L W D + Y+V+++ E KT+T +
Sbjct: 17410 PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE--- 17466
Query: 171 CNITGLRPATSYVFSI 186
C +TGL+ +Y F +
Sbjct: 17467 CVVTGLQQGKTYRFRV 17482
Score = 29.3 bits (64), Expect = 9.5
Identities = 27/122 (22%), Positives = 53/122 (43%), Gaps = 13/122 (10%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSN-DTAASEYK--YVVKHKMENEKTITVVHQPW----C 171
P P + +++ ++WK D SE +V + + ++ + + + P C
Sbjct: 20572 PGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRC 20631
Query: 172 NITGLRPATSYVFSIT----PGIGNETWGDPRVI--KVITEPIPVSDLRVALTGVRKAAL 225
+TGL+ ++Y F ++ GIG + V+ P P S+ V T + A+L
Sbjct: 20632 KVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASL 20691
Query: 226 SW 227
+W
Sbjct: 20692 AW 20693
Score = 29.3 bits (64), Expect = 9.5
Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSNDTAASEY--KYVVKHKMENEKT 162
P+P+ D+ + T+VIL+W D +YVV+ K + E+T
Sbjct: 27463 PAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQT 27508
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 45.1 bits (105), Expect = 2e-04
Identities = 51/202 (25%), Positives = 83/202 (41%), Gaps = 21/202 (10%)
Query: 101 QGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSN--DTAASEYKYVVKHKME 158
+ S+GT A PSP ++K I+ +V +TW+ D + Y+V+ +
Sbjct: 16711 ENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREA 16770
Query: 159 NEKT----ITVVHQPWCNITGLRPATSYVFSITP----GIG-NETWGDPRVIKVITEPIP 209
K+ +T H+ I L+ SY F +T GIG DP IKV P P
Sbjct: 16771 TRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADP--IKVAEVPQP 16828
Query: 210 VSDLRVALTGVRKAALSWS---NGNGTASCRVLLESIGSHEELTQD----SRLQVNISGL 262
+ V +LSW+ + G+ + ++E H E + LQ I+ L
Sbjct: 16829 PGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNL 16888
Query: 263 KPGVQYNINPYLLQSNKTKGDP 284
G +Y + + + K + DP
Sbjct: 16889 TQGEEY-LFRVVAVNEKGRSDP 16909
Score = 42.4 bits (98), Expect = 0.001
Identities = 41/171 (23%), Positives = 69/171 (40%), Gaps = 21/171 (12%)
Query: 119 PSPVFDIKAVSISPTNVILTW--KSNDTAASEYKYVVKHKMENEKTITV----VHQPWCN 172
P PV D+K ++ T+ ++W ND + Y+V+ + + KT + V + +
Sbjct: 12394 PGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFH 12453
Query: 173 ITGLRPATSYVFSIT------PGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALS 226
+T L P Y F +T PG+ + ++EP P L V A L+
Sbjct: 12454 VTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLA 12513
Query: 227 W--SNGNGTASCRVLLESIGSHE-------ELTQDSRLQVNISGLKPGVQY 268
W +G A + S E E + L + ++GLK G +Y
Sbjct: 12514 WLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKY 12564
Score = 39.7 bits (91), Expect = 0.007
Identities = 45/203 (22%), Positives = 77/203 (37%), Gaps = 23/203 (11%)
Query: 101 QGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSN--DTAASEYKYVVKHKME 158
+ S+G+ A P P D+K ++ T+V LTW D + Y+V+ +
Sbjct: 15629 ENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRES 15688
Query: 159 NEKTITVV----HQPWCNITGLRPATSYVFSITP------GIGNETWGDPRVIKVITEPI 208
K + V H+ + L+ SY F + G+ ET +K P+
Sbjct: 15689 TRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAET---AESVKASERPL 15745
Query: 209 PVSDLRVALTGVRKAALSWSNGNGTASCRVL-----LESIGSHEELT--QDSRLQVNISG 261
P + + +LSW R+L +++ GS + T + I+G
Sbjct: 15746 PPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITG 15805
Query: 262 LKPGVQYNINPYLLQSNKTKGDP 284
L G +Y+ Q+ K DP
Sbjct: 15806 LIQGEEYSFR-VSAQNEKGISDP 15827
Score = 35.8 bits (81), Expect = 0.10
Identities = 39/168 (23%), Positives = 65/168 (38%), Gaps = 21/168 (12%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSN--DTAASEYKYVVKHKMENEKTITVVHQPWCNITGL 176
P P ++ IS + +TW+ D + YVV+ + K+ + V C+ T
Sbjct: 13482 PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTE-CSKTSF 13540
Query: 177 RPAT-----SYVFSITP----GIGNETWGDPR-VIKVITEPIPVSDLRVALTGVRKAALS 226
R A SY F + GIG+ G+ R +K P PV DL+V ++
Sbjct: 13541 RVANLEEGKSYFFRVFAENEYGIGDP--GETRDAVKASQTPGPVVDLKVRSVSKSSCSIG 13598
Query: 227 WSNGNGTASCRVL------LESIGSHEELTQDSRLQVNISGLKPGVQY 268
W + R++ L + + + LQ + L G +Y
Sbjct: 13599 WKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEY 13646
Score = 33.1 bits (74), Expect = 0.66
Identities = 30/114 (26%), Positives = 43/114 (37%), Gaps = 14/114 (12%)
Query: 376 NISATSLTLIWKVSDNESSSNYTYKIHVAGETDS-------SNLNVSEPRAVIPGLRSST 428
NI+ S+TL W +++ S I E S S +SE R + GL
Sbjct: 21857 NITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGN 21916
Query: 429 FYNITVCPV----LGDIEGTPGFLQVH---TPPVPVSDFRVTVVSTTEIGLAWS 475
Y V +G G ++ PP P + +VT S T + L WS
Sbjct: 21917 EYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWS 21970
Score = 32.3 bits (72), Expect = 1.1
Identities = 41/169 (24%), Positives = 67/169 (39%), Gaps = 20/169 (11%)
Query: 119 PSPVFDIKAVSISPTNVILTWK--SNDTAASEYKYVVKHK---MENEKTITV-VHQPWCN 172
P P +K +S +V +TW+ + D A Y+V+ + M KT+T +
Sbjct: 23233 PGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYR 23292
Query: 173 ITGLRPATSYVFSITP----GIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWS 228
I+GL T Y F + P GIG E + V P+ + L V L+W
Sbjct: 23293 ISGLVEGTMYYFRVLPENIYGIG-EPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWE 23351
Query: 229 N---GNGTASCRVLLESIGSHEE------LTQDSRLQVNISGLKPGVQY 268
G+ +LE+ + E + + L+ ++ L G QY
Sbjct: 23352 KPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQY 23400
Score = 31.6 bits (70), Expect = 1.9
Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Query: 453 PPVPVSDFRVTVVSTTEIGLAWSSHDAE------SFQMHITQEGAGN-SRVEITTNQSII 505
PP P D V TE+ L W+ D + + + +EG + + + TN +
Sbjct: 11104 PPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECV 11163
Query: 506 IGGLFPGTKYCFEI 519
+ GL G Y F +
Sbjct: 11164 VTGLQQGKTYRFRV 11177
Score = 31.6 bits (70), Expect = 1.9
Identities = 28/119 (23%), Positives = 45/119 (37%), Gaps = 11/119 (9%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSN--DTAASEYKYVVKHKMENEKT----ITVVHQPWCN 172
P PV +++ I+ +V L W D + Y+V+ + K+ T H+
Sbjct: 14563 PGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYK 14622
Query: 173 ITGLRPATSYVFSITP----GIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSW 227
+TGL Y F + GIG T +K P P L + +L+W
Sbjct: 14623 VTGLSEGCEYFFRVMAENEYGIGEPT-ETTEPVKASEAPSPPDSLNIMDITKSTVSLAW 14680
Score = 29.6 bits (65), Expect = 7.3
Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 5/89 (5%)
Query: 103 SNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKS-NDTAASEYK-YVVKH---KM 157
S G+ A+ + P PV D+K V + +L W D SE ++++ KM
Sbjct: 8876 SCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKM 8935
Query: 158 ENEKTITVVHQPWCNITGLRPATSYVFSI 186
+ + C+ITGL Y F +
Sbjct: 8936 HTWRQPIETERSKCDITGLLEGQEYKFRV 8964
Score = 29.6 bits (65), Expect = 7.3
Identities = 21/76 (27%), Positives = 34/76 (44%), Gaps = 11/76 (14%)
Query: 119 PSPVFDIKAVSISPTNVILTWK--SNDTAASEYKYVVKHKMENE------KTITVVHQPW 170
P P D+ V + T V L W D + Y+V+++ E KT+T +
Sbjct: 11105 PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE--- 11161
Query: 171 CNITGLRPATSYVFSI 186
C +TGL+ +Y F +
Sbjct: 11162 CVVTGLQQGKTYRFRV 11177
Score = 29.3 bits (64), Expect = 9.5
Identities = 27/122 (22%), Positives = 53/122 (43%), Gaps = 13/122 (10%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSN-DTAASEYK--YVVKHKMENEKTITVVHQPW----C 171
P P + +++ ++WK D SE +V + + ++ + + + P C
Sbjct: 14267 PGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRC 14326
Query: 172 NITGLRPATSYVFSIT----PGIGNETWGDPRVI--KVITEPIPVSDLRVALTGVRKAAL 225
+TGL+ ++Y F ++ GIG + V+ P P S+ V T + A+L
Sbjct: 14327 KVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASL 14386
Query: 226 SW 227
+W
Sbjct: 14387 AW 14388
Score = 29.3 bits (64), Expect = 9.5
Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSNDTAASEY--KYVVKHKMENEKT 162
P+P+ D+ + T+VIL+W D +YVV+ K + E+T
Sbjct: 21158 PAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQT 21203
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 45.1 bits (105), Expect = 2e-04
Identities = 51/202 (25%), Positives = 83/202 (41%), Gaps = 21/202 (10%)
Query: 101 QGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSN--DTAASEYKYVVKHKME 158
+ S+GT A PSP ++K I+ +V +TW+ D + Y+V+ +
Sbjct: 16644 ENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREA 16703
Query: 159 NEKT----ITVVHQPWCNITGLRPATSYVFSITP----GIG-NETWGDPRVIKVITEPIP 209
K+ +T H+ I L+ SY F +T GIG DP IKV P P
Sbjct: 16704 TRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADP--IKVAEVPQP 16761
Query: 210 VSDLRVALTGVRKAALSWS---NGNGTASCRVLLESIGSHEELTQD----SRLQVNISGL 262
+ V +LSW+ + G+ + ++E H E + LQ I+ L
Sbjct: 16762 PGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNL 16821
Query: 263 KPGVQYNINPYLLQSNKTKGDP 284
G +Y + + + K + DP
Sbjct: 16822 TQGEEY-LFRVVAVNEKGRSDP 16842
Score = 42.4 bits (98), Expect = 0.001
Identities = 41/171 (23%), Positives = 69/171 (40%), Gaps = 21/171 (12%)
Query: 119 PSPVFDIKAVSISPTNVILTW--KSNDTAASEYKYVVKHKMENEKTITV----VHQPWCN 172
P PV D+K ++ T+ ++W ND + Y+V+ + + KT + V + +
Sbjct: 12327 PGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFH 12386
Query: 173 ITGLRPATSYVFSIT------PGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALS 226
+T L P Y F +T PG+ + ++EP P L V A L+
Sbjct: 12387 VTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLA 12446
Query: 227 W--SNGNGTASCRVLLESIGSHE-------ELTQDSRLQVNISGLKPGVQY 268
W +G A + S E E + L + ++GLK G +Y
Sbjct: 12447 WLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKY 12497
Score = 39.7 bits (91), Expect = 0.007
Identities = 45/203 (22%), Positives = 77/203 (37%), Gaps = 23/203 (11%)
Query: 101 QGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSN--DTAASEYKYVVKHKME 158
+ S+G+ A P P D+K ++ T+V LTW D + Y+V+ +
Sbjct: 15562 ENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRES 15621
Query: 159 NEKTITVV----HQPWCNITGLRPATSYVFSITP------GIGNETWGDPRVIKVITEPI 208
K + V H+ + L+ SY F + G+ ET +K P+
Sbjct: 15622 TRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAET---AESVKASERPL 15678
Query: 209 PVSDLRVALTGVRKAALSWSNGNGTASCRVL-----LESIGSHEELT--QDSRLQVNISG 261
P + + +LSW R+L +++ GS + T + I+G
Sbjct: 15679 PPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITG 15738
Query: 262 LKPGVQYNINPYLLQSNKTKGDP 284
L G +Y+ Q+ K DP
Sbjct: 15739 LIQGEEYSFR-VSAQNEKGISDP 15760
Score = 35.8 bits (81), Expect = 0.10
Identities = 39/168 (23%), Positives = 65/168 (38%), Gaps = 21/168 (12%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSN--DTAASEYKYVVKHKMENEKTITVVHQPWCNITGL 176
P P ++ IS + +TW+ D + YVV+ + K+ + V C+ T
Sbjct: 13415 PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTE-CSKTSF 13473
Query: 177 RPAT-----SYVFSITP----GIGNETWGDPR-VIKVITEPIPVSDLRVALTGVRKAALS 226
R A SY F + GIG+ G+ R +K P PV DL+V ++
Sbjct: 13474 RVANLEEGKSYFFRVFAENEYGIGDP--GETRDAVKASQTPGPVVDLKVRSVSKSSCSIG 13531
Query: 227 WSNGNGTASCRVL------LESIGSHEELTQDSRLQVNISGLKPGVQY 268
W + R++ L + + + LQ + L G +Y
Sbjct: 13532 WKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEY 13579
Score = 33.1 bits (74), Expect = 0.66
Identities = 30/114 (26%), Positives = 43/114 (37%), Gaps = 14/114 (12%)
Query: 376 NISATSLTLIWKVSDNESSSNYTYKIHVAGETDS-------SNLNVSEPRAVIPGLRSST 428
NI+ S+TL W +++ S I E S S +SE R + GL
Sbjct: 21790 NITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGN 21849
Query: 429 FYNITVCPV----LGDIEGTPGFLQVH---TPPVPVSDFRVTVVSTTEIGLAWS 475
Y V +G G ++ PP P + +VT S T + L WS
Sbjct: 21850 EYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWS 21903
Score = 32.3 bits (72), Expect = 1.1
Identities = 41/169 (24%), Positives = 67/169 (39%), Gaps = 20/169 (11%)
Query: 119 PSPVFDIKAVSISPTNVILTWK--SNDTAASEYKYVVKHK---MENEKTITV-VHQPWCN 172
P P +K +S +V +TW+ + D A Y+V+ + M KT+T +
Sbjct: 23166 PGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYR 23225
Query: 173 ITGLRPATSYVFSITP----GIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWS 228
I+GL T Y F + P GIG E + V P+ + L V L+W
Sbjct: 23226 ISGLVEGTMYYFRVLPENIYGIG-EPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWE 23284
Query: 229 N---GNGTASCRVLLESIGSHEE------LTQDSRLQVNISGLKPGVQY 268
G+ +LE+ + E + + L+ ++ L G QY
Sbjct: 23285 KPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQY 23333
Score = 31.6 bits (70), Expect = 1.9
Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Query: 453 PPVPVSDFRVTVVSTTEIGLAWSSHDAE------SFQMHITQEGAGN-SRVEITTNQSII 505
PP P D V TE+ L W+ D + + + +EG + + + TN +
Sbjct: 11037 PPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECV 11096
Query: 506 IGGLFPGTKYCFEI 519
+ GL G Y F +
Sbjct: 11097 VTGLQQGKTYRFRV 11110
Score = 31.6 bits (70), Expect = 1.9
Identities = 28/119 (23%), Positives = 45/119 (37%), Gaps = 11/119 (9%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSN--DTAASEYKYVVKHKMENEKT----ITVVHQPWCN 172
P PV +++ I+ +V L W D + Y+V+ + K+ T H+
Sbjct: 14496 PGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYK 14555
Query: 173 ITGLRPATSYVFSITP----GIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSW 227
+TGL Y F + GIG T +K P P L + +L+W
Sbjct: 14556 VTGLSEGCEYFFRVMAENEYGIGEPT-ETTEPVKASEAPSPPDSLNIMDITKSTVSLAW 14613
Score = 29.6 bits (65), Expect = 7.3
Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 5/89 (5%)
Query: 103 SNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKS-NDTAASEYK-YVVKH---KM 157
S G+ A+ + P PV D+K V + +L W D SE ++++ KM
Sbjct: 8809 SCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKM 8868
Query: 158 ENEKTITVVHQPWCNITGLRPATSYVFSI 186
+ + C+ITGL Y F +
Sbjct: 8869 HTWRQPIETERSKCDITGLLEGQEYKFRV 8897
Score = 29.6 bits (65), Expect = 7.3
Identities = 21/76 (27%), Positives = 34/76 (44%), Gaps = 11/76 (14%)
Query: 119 PSPVFDIKAVSISPTNVILTWK--SNDTAASEYKYVVKHKMENE------KTITVVHQPW 170
P P D+ V + T V L W D + Y+V+++ E KT+T +
Sbjct: 11038 PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE--- 11094
Query: 171 CNITGLRPATSYVFSI 186
C +TGL+ +Y F +
Sbjct: 11095 CVVTGLQQGKTYRFRV 11110
Score = 29.3 bits (64), Expect = 9.5
Identities = 27/122 (22%), Positives = 53/122 (43%), Gaps = 13/122 (10%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSN-DTAASEYK--YVVKHKMENEKTITVVHQPW----C 171
P P + +++ ++WK D SE +V + + ++ + + + P C
Sbjct: 14200 PGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRC 14259
Query: 172 NITGLRPATSYVFSIT----PGIGNETWGDPRVI--KVITEPIPVSDLRVALTGVRKAAL 225
+TGL+ ++Y F ++ GIG + V+ P P S+ V T + A+L
Sbjct: 14260 KVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASL 14319
Query: 226 SW 227
+W
Sbjct: 14320 AW 14321
Score = 29.3 bits (64), Expect = 9.5
Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSNDTAASEY--KYVVKHKMENEKT 162
P+P+ D+ + T+VIL+W D +YVV+ K + E+T
Sbjct: 21091 PAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQT 21136
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 45.1 bits (105), Expect = 2e-04
Identities = 51/202 (25%), Positives = 83/202 (41%), Gaps = 21/202 (10%)
Query: 101 QGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSN--DTAASEYKYVVKHKME 158
+ S+GT A PSP ++K I+ +V +TW+ D + Y+V+ +
Sbjct: 16519 ENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREA 16578
Query: 159 NEKT----ITVVHQPWCNITGLRPATSYVFSITP----GIG-NETWGDPRVIKVITEPIP 209
K+ +T H+ I L+ SY F +T GIG DP IKV P P
Sbjct: 16579 TRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADP--IKVAEVPQP 16636
Query: 210 VSDLRVALTGVRKAALSWS---NGNGTASCRVLLESIGSHEELTQD----SRLQVNISGL 262
+ V +LSW+ + G+ + ++E H E + LQ I+ L
Sbjct: 16637 PGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNL 16696
Query: 263 KPGVQYNINPYLLQSNKTKGDP 284
G +Y + + + K + DP
Sbjct: 16697 TQGEEY-LFRVVAVNEKGRSDP 16717
Score = 42.4 bits (98), Expect = 0.001
Identities = 41/171 (23%), Positives = 69/171 (40%), Gaps = 21/171 (12%)
Query: 119 PSPVFDIKAVSISPTNVILTW--KSNDTAASEYKYVVKHKMENEKTITV----VHQPWCN 172
P PV D+K ++ T+ ++W ND + Y+V+ + + KT + V + +
Sbjct: 12202 PGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFH 12261
Query: 173 ITGLRPATSYVFSIT------PGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALS 226
+T L P Y F +T PG+ + ++EP P L V A L+
Sbjct: 12262 VTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLA 12321
Query: 227 W--SNGNGTASCRVLLESIGSHE-------ELTQDSRLQVNISGLKPGVQY 268
W +G A + S E E + L + ++GLK G +Y
Sbjct: 12322 WLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKY 12372
Score = 39.7 bits (91), Expect = 0.007
Identities = 45/203 (22%), Positives = 77/203 (37%), Gaps = 23/203 (11%)
Query: 101 QGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKSN--DTAASEYKYVVKHKME 158
+ S+G+ A P P D+K ++ T+V LTW D + Y+V+ +
Sbjct: 15437 ENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRES 15496
Query: 159 NEKTITVV----HQPWCNITGLRPATSYVFSITP------GIGNETWGDPRVIKVITEPI 208
K + V H+ + L+ SY F + G+ ET +K P+
Sbjct: 15497 TRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAET---AESVKASERPL 15553
Query: 209 PVSDLRVALTGVRKAALSWSNGNGTASCRVL-----LESIGSHEELT--QDSRLQVNISG 261
P + + +LSW R+L +++ GS + T + I+G
Sbjct: 15554 PPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITG 15613
Query: 262 LKPGVQYNINPYLLQSNKTKGDP 284
L G +Y+ Q+ K DP
Sbjct: 15614 LIQGEEYSFR-VSAQNEKGISDP 15635
Score = 35.8 bits (81), Expect = 0.10
Identities = 39/168 (23%), Positives = 65/168 (38%), Gaps = 21/168 (12%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSN--DTAASEYKYVVKHKMENEKTITVVHQPWCNITGL 176
P P ++ IS + +TW+ D + YVV+ + K+ + V C+ T
Sbjct: 13290 PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTE-CSKTSF 13348
Query: 177 RPAT-----SYVFSITP----GIGNETWGDPR-VIKVITEPIPVSDLRVALTGVRKAALS 226
R A SY F + GIG+ G+ R +K P PV DL+V ++
Sbjct: 13349 RVANLEEGKSYFFRVFAENEYGIGDP--GETRDAVKASQTPGPVVDLKVRSVSKSSCSIG 13406
Query: 227 WSNGNGTASCRVL------LESIGSHEELTQDSRLQVNISGLKPGVQY 268
W + R++ L + + + LQ + L G +Y
Sbjct: 13407 WKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEY 13454
Score = 33.1 bits (74), Expect = 0.66
Identities = 30/114 (26%), Positives = 43/114 (37%), Gaps = 14/114 (12%)
Query: 376 NISATSLTLIWKVSDNESSSNYTYKIHVAGETDS-------SNLNVSEPRAVIPGLRSST 428
NI+ S+TL W +++ S I E S S +SE R + GL
Sbjct: 21665 NITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGN 21724
Query: 429 FYNITVCPV----LGDIEGTPGFLQVH---TPPVPVSDFRVTVVSTTEIGLAWS 475
Y V +G G ++ PP P + +VT S T + L WS
Sbjct: 21725 EYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWS 21778
Score = 32.3 bits (72), Expect = 1.1
Identities = 41/169 (24%), Positives = 67/169 (39%), Gaps = 20/169 (11%)
Query: 119 PSPVFDIKAVSISPTNVILTWK--SNDTAASEYKYVVKHK---MENEKTITV-VHQPWCN 172
P P +K +S +V +TW+ + D A Y+V+ + M KT+T +
Sbjct: 23041 PGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYR 23100
Query: 173 ITGLRPATSYVFSITP----GIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWS 228
I+GL T Y F + P GIG E + V P+ + L V L+W
Sbjct: 23101 ISGLVEGTMYYFRVLPENIYGIG-EPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWE 23159
Query: 229 N---GNGTASCRVLLESIGSHEE------LTQDSRLQVNISGLKPGVQY 268
G+ +LE+ + E + + L+ ++ L G QY
Sbjct: 23160 KPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQY 23208
Score = 31.6 bits (70), Expect = 1.9
Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Query: 453 PPVPVSDFRVTVVSTTEIGLAWSSHDAE------SFQMHITQEGAGN-SRVEITTNQSII 505
PP P D V TE+ L W+ D + + + +EG + + + TN +
Sbjct: 10912 PPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECV 10971
Query: 506 IGGLFPGTKYCFEI 519
+ GL G Y F +
Sbjct: 10972 VTGLQQGKTYRFRV 10985
Score = 31.6 bits (70), Expect = 1.9
Identities = 28/119 (23%), Positives = 45/119 (37%), Gaps = 11/119 (9%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSN--DTAASEYKYVVKHKMENEKT----ITVVHQPWCN 172
P PV +++ I+ +V L W D + Y+V+ + K+ T H+
Sbjct: 14371 PGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYK 14430
Query: 173 ITGLRPATSYVFSITP----GIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSW 227
+TGL Y F + GIG T +K P P L + +L+W
Sbjct: 14431 VTGLSEGCEYFFRVMAENEYGIGEPT-ETTEPVKASEAPSPPDSLNIMDITKSTVSLAW 14488
Score = 29.6 bits (65), Expect = 7.3
Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 5/89 (5%)
Query: 103 SNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWKS-NDTAASEYK-YVVKH---KM 157
S G+ A+ + P PV D+K V + +L W D SE ++++ KM
Sbjct: 8684 SCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKM 8743
Query: 158 ENEKTITVVHQPWCNITGLRPATSYVFSI 186
+ + C+ITGL Y F +
Sbjct: 8744 HTWRQPIETERSKCDITGLLEGQEYKFRV 8772
Score = 29.6 bits (65), Expect = 7.3
Identities = 21/76 (27%), Positives = 34/76 (44%), Gaps = 11/76 (14%)
Query: 119 PSPVFDIKAVSISPTNVILTWK--SNDTAASEYKYVVKHKMENE------KTITVVHQPW 170
P P D+ V + T V L W D + Y+V+++ E KT+T +
Sbjct: 10913 PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE--- 10969
Query: 171 CNITGLRPATSYVFSI 186
C +TGL+ +Y F +
Sbjct: 10970 CVVTGLQQGKTYRFRV 10985
Score = 29.3 bits (64), Expect = 9.5
Identities = 27/122 (22%), Positives = 53/122 (43%), Gaps = 13/122 (10%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSN-DTAASEYK--YVVKHKMENEKTITVVHQPW----C 171
P P + +++ ++WK D SE +V + + ++ + + + P C
Sbjct: 14075 PGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRC 14134
Query: 172 NITGLRPATSYVFSIT----PGIGNETWGDPRVI--KVITEPIPVSDLRVALTGVRKAAL 225
+TGL+ ++Y F ++ GIG + V+ P P S+ V T + A+L
Sbjct: 14135 KVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASL 14194
Query: 226 SW 227
+W
Sbjct: 14195 AW 14196
Score = 29.3 bits (64), Expect = 9.5
Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 119 PSPVFDIKAVSISPTNVILTWKSNDTAASEY--KYVVKHKMENEKT 162
P+P+ D+ + T+VIL+W D +YVV+ K + E+T
Sbjct: 20966 PAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQT 21011
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/197 (23%), Positives = 77/197 (39%), Gaps = 39/197 (19%)
Query: 305 TAPVHDESLVGPVD----PSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAI 360
T V + +GP P++ + + + L GL+P T Y+ V + G +
Sbjct: 944 TVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPGPFSPPV 1003
Query: 361 EFRT---NAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEP 417
+RT + + + I TS+ L W+ DN +S YKI G T +++
Sbjct: 1004 RYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPDNYNSPT-PYKIQYNGLT--LDVDGRTT 1060
Query: 418 RAVIPGLRSSTFYN----------------ITVCPVLGDIEGTP---------GFLQVHT 452
+ +I L+ TFYN +T + G P GF+ V+
Sbjct: 1061 KKLITHLKPHTFYNFVLTNRGSSLGGLQQTVTAWTAFNLLNGKPSVAPKPDADGFIMVYL 1120
Query: 453 P----PVPVSDFRVTVV 465
P PVPV + + +V
Sbjct: 1121 PDGQSPVPVQSYFIVMV 1137
Score = 37.4 bits (85), Expect = 0.035
Identities = 55/230 (23%), Positives = 88/230 (38%), Gaps = 20/230 (8%)
Query: 328 TEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTN----AIQVFDVTAVNISATSLT 383
T + GL P + Y V + + G +++ RT A +V A +SAT++
Sbjct: 372 TRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMI 431
Query: 384 LIWKVSDNESSSNYTYKI-------HVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCP 436
+ W+ + Y++ H G N++ S V L T Y + V
Sbjct: 432 VQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDET-YTVRVLA 490
Query: 437 VLGDIEGTPGF-LQVHTP---PVPVSDFRVTVVSTTEIGLAWSSHDAESFQMH--ITQEG 490
+G +QV T P + R S T I L+WS ES + + +EG
Sbjct: 491 FTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREG 550
Query: 491 AGNSRVEITTNQ--SIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRT 538
V T + S ++ L P T+Y F + + P G + V RT
Sbjct: 551 DHGREVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRT 600
Score = 35.4 bits (80), Expect = 0.13
Identities = 33/139 (23%), Positives = 54/139 (38%), Gaps = 8/139 (5%)
Query: 407 TDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVS 466
T ++ V + ++ S Y LG IE P P + VT +
Sbjct: 273 TPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPM-VTENT 331
Query: 467 TTEIGLAWSSHDAESFQMHI------TQEGAGNSRVEITTNQSIIIGGLFPGTKYCFEIV 520
T I + W S + + ++ +Q+G + +ITT + IGGL P ++Y +
Sbjct: 332 ATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTR-YSIGGLSPNSEYEIWVS 390
Query: 521 PKGPNGTEGASRTVCNRTG 539
G S +V RTG
Sbjct: 391 AVNSIGQGPPSESVVTRTG 409
Score = 31.2 bits (69), Expect = 2.5
Identities = 97/474 (20%), Positives = 170/474 (35%), Gaps = 82/474 (17%)
Query: 36 AGGTPSPIPDPSVATVATGENGITQ-ISSTAESFHKQNGTGTPQVE-----TNTSEDGES 89
A GTP + + + T ++G +S + ++ G Q++ T S G S
Sbjct: 321 APGTPMVTENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLS 380
Query: 90 SGANDSLRTPEQGSNGTDGASQKTPSSTGP----SPVFDIKAVSISPTNVILTWKSNDTA 145
+ + S G S+ + TG S +++A +S T +I+ W+
Sbjct: 381 PNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEP 440
Query: 146 ASEYK-YVVKHKMENEKTI------TVVHQPWCNITGLRPATSYVFSITP--GIGNETWG 196
+ Y V + ME E + V + L +Y + +G+
Sbjct: 441 NGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLS 500
Query: 197 DPRVIKVITE---PIPVSDLRVALTGVRKAALSWSNGNGTASCRV-LLESIGSHEE---L 249
DP I+V T+ P +LR LSWS + + LL G H
Sbjct: 501 DP--IQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGREVGR 558
Query: 250 TQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAPV- 308
T D + LKP +Y + L + +G LG + T +S+ +P V
Sbjct: 559 TFDPTTSYVVEDLKPNTEY---AFRLAARSPQG--LGAFTPVVRQRTLQSKPSAPPQDVK 613
Query: 309 --------------------HDESLVG---------PVDPS----SGQQSRDTEVLLVGL 335
H+ +LVG DP +G T++LL L
Sbjct: 614 CVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEAL 673
Query: 336 EPGTRYNATVYSQAANGTEGQPQAIEFRTN----AIQVFDVTAVNISATSLTLIWK--VS 389
E T+Y T + G + + RT+ + V A ++AT++ ++W+
Sbjct: 674 EKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAP 733
Query: 390 DNESSSNYTYKIH--------VAGETDSSNLNVSEPR-AVIPGLRSSTFYNITV 434
+ Y++H G ++ +++ + VI L+ T Y+ITV
Sbjct: 734 GRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQEMVITNLQPETAYSITV 787
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/197 (23%), Positives = 77/197 (39%), Gaps = 39/197 (19%)
Query: 305 TAPVHDESLVGPVD----PSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAI 360
T V + +GP P++ + + + L GL+P T Y+ V + G +
Sbjct: 966 TVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPGPFSPPV 1025
Query: 361 EFRT---NAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEP 417
+RT + + + I TS+ L W+ DN +S YKI G T +++
Sbjct: 1026 RYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPDNYNSPT-PYKIQYNGLT--LDVDGRTT 1082
Query: 418 RAVIPGLRSSTFYN----------------ITVCPVLGDIEGTP---------GFLQVHT 452
+ +I L+ TFYN +T + G P GF+ V+
Sbjct: 1083 KKLITHLKPHTFYNFVLTNRGSSLGGLQQTVTAWTAFNLLNGKPSVAPKPDADGFIMVYL 1142
Query: 453 P----PVPVSDFRVTVV 465
P PVPV + + +V
Sbjct: 1143 PDGQSPVPVQSYFIVMV 1159
Score = 37.4 bits (85), Expect = 0.035
Identities = 55/230 (23%), Positives = 88/230 (38%), Gaps = 20/230 (8%)
Query: 328 TEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTN----AIQVFDVTAVNISATSLT 383
T + GL P + Y V + + G +++ RT A +V A +SAT++
Sbjct: 385 TRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMI 444
Query: 384 LIWKVSDNESSSNYTYKI-------HVAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCP 436
+ W+ + Y++ H G N++ S V L T Y + V
Sbjct: 445 VQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDET-YTVRVLA 503
Query: 437 VLGDIEGTPGF-LQVHTP---PVPVSDFRVTVVSTTEIGLAWSSHDAESFQMH--ITQEG 490
+G +QV T P + R S T I L+WS ES + + +EG
Sbjct: 504 FTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREG 563
Query: 491 AGNSRVEITTNQ--SIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRT 538
V T + S ++ L P T+Y F + + P G + V RT
Sbjct: 564 DHGREVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRT 613
Score = 35.4 bits (80), Expect = 0.13
Identities = 33/139 (23%), Positives = 54/139 (38%), Gaps = 8/139 (5%)
Query: 407 TDSSNLNVSEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVS 466
T ++ V + ++ S Y LG IE P P + VT +
Sbjct: 286 TPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPM-VTENT 344
Query: 467 TTEIGLAWSSHDAESFQMHI------TQEGAGNSRVEITTNQSIIIGGLFPGTKYCFEIV 520
T I + W S + + ++ +Q+G + +ITT + IGGL P ++Y +
Sbjct: 345 ATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTR-YSIGGLSPNSEYEIWVS 403
Query: 521 PKGPNGTEGASRTVCNRTG 539
G S +V RTG
Sbjct: 404 AVNSIGQGPPSESVVTRTG 422
Score = 30.4 bits (67), Expect = 4.3
Identities = 97/483 (20%), Positives = 168/483 (34%), Gaps = 91/483 (18%)
Query: 36 AGGTPSPIPDPSVATVATGENGITQ-ISSTAESFHKQNGTGTPQVE-----TNTSEDGES 89
A GTP + + + T ++G +S + ++ G Q++ T S G S
Sbjct: 334 APGTPMVTENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLS 393
Query: 90 SGANDSLRTPEQGSNGTDGASQKTPSSTGP----SPVFDIKAVSISPTNVILTWKSNDTA 145
+ + S G S+ + TG S +++A +S T +I+ W+
Sbjct: 394 PNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEP 453
Query: 146 ASEYK-YVVKHKMENEKTI------TVVHQPWCNITGLRPATSYVFSITP--GIGNETWG 196
+ Y V + ME E + V + L +Y + +G+
Sbjct: 454 NGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLS 513
Query: 197 DPRVIKVITE---PIPVSDLRVALTGVRKAALSWSNGNGTASCRV-LLESIGSHEE---L 249
DP I+V T+ P +LR LSWS + + LL G H
Sbjct: 514 DP--IQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGREVGR 571
Query: 250 TQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAPV- 308
T D + LKP +Y + L + +G LG + T +S+ +P V
Sbjct: 572 TFDPTTSYVVEDLKPNTEY---AFRLAARSPQG--LGAFTPVVRQRTLQSKPSAPPQDVK 626
Query: 309 --------------------HDESLVG---------PVDPS----SGQQSRDTEVLLVGL 335
H+ +LVG DP +G T++LL L
Sbjct: 627 CVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEAL 686
Query: 336 EPGTRYNATVYSQAANGTEGQPQAIEFRTN----AIQVFDVTAVNISATSLTLIWK--VS 389
E T+Y T + G + + RT+ + V A ++AT++ ++W+
Sbjct: 687 EKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAP 746
Query: 390 DNESSSNYTYKIH------------------VAGETDSSNLNVSEPRAVIPGLRSSTFYN 431
+ Y++H + + + +E VI L+ T Y+
Sbjct: 747 GRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYS 806
Query: 432 ITV 434
ITV
Sbjct: 807 ITV 809
>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
Length = 1447
Score = 43.9 bits (102), Expect = 4e-04
Identities = 96/459 (20%), Positives = 159/459 (34%), Gaps = 84/459 (18%)
Query: 99 PEQGSNGTDGASQKTPSSTGPSPVFDIKAVSISPTNVILTWK----SNDTAASEYKYVVK 154
P + S A+Q P P PV +++AVS SPT++++TW+ +N + +
Sbjct: 510 PGESSQPIKVATQ--PELQVPGPVENLQAVSTSPTSILITWEPPAYANGPVQGYRLFCTE 567
Query: 155 HKMENEKTITVVHQPWCNITGLRPATSYVFSIT------PGIGNETWGDPRVIKVITEP- 207
E+ I V + + GL+ T Y PG+ + D V+ + P
Sbjct: 568 VSTGKEQNIEVDGLSY-KLEGLKKFTEYSLRFLAYNRYGPGVSTD---DITVVTLSDVPS 623
Query: 208 IPVSDLRVALTGVRKAALSW-------SNGNGTA-SCRVLLESIGSHEELTQDSRLQVNI 259
P ++ + + R +SW NG T R + E + + L
Sbjct: 624 APPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWYLF 683
Query: 260 SGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAPVHDESLVGPVDP 319
+GL+ G QY+ + N T G P A E DES V P P
Sbjct: 684 TGLEKGSQYSFQVSAMTVNGT-GPP---SNWYTAETPENDL---------DESQV-PDQP 729
Query: 320 SSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISA 379
SS T +++ P N V G P A R ++ Q +
Sbjct: 730 SSLHVRPQTNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRY--------- 780
Query: 380 TSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAVIPGLRSSTFYNIT------ 433
+ + ESSS+Y + +P S+T +IT
Sbjct: 781 ------YSIERLESSSHYVISLKAFNNAGEG----------VPLYESATTRSITDPTDPV 824
Query: 434 -VCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQ--------- 483
P+L D + L TP +P + ++ + ++W+ + Q
Sbjct: 825 DYYPLLDDFPTSVPDLS--TPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYT 882
Query: 484 --MHITQEGAGNSRVEITTNQSIIIGGLFPGTKYCFEIV 520
+ + + E TT+ S GL P T Y F ++
Sbjct: 883 VRWRTSFSASAKYKSEDTTSLSYTATGLKPNTMYEFSVM 921
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
sapiens]
Length = 1899
Score = 43.5 bits (101), Expect = 5e-04
Identities = 38/145 (26%), Positives = 59/145 (40%), Gaps = 5/145 (3%)
Query: 314 VGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVT 373
VG +P T L L P T Y+ VY+Q +G P + T + V D+
Sbjct: 989 VGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLS-VPLTDQGTTLYLNVTDLK 1047
Query: 374 AVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNV--SEPRAVIPGLRSSTFYN 431
I + + W S + ++++Y K+ A T + V SE GL T Y
Sbjct: 1048 TYQIGWDTFCVKW--SPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYG 1105
Query: 432 ITVCPVLGDIEGTPGFLQVHTPPVP 456
+TV ++EG ++ HT P
Sbjct: 1106 VTVFVQTPNLEGPGVSVKEHTTVKP 1130
Score = 42.4 bits (98), Expect = 0.001
Identities = 72/317 (22%), Positives = 118/317 (37%), Gaps = 40/317 (12%)
Query: 253 SRLQVN--ISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGL----------DASNTERSR 300
SR++ + + LKP +Y +N Y + ++ GTE L D T
Sbjct: 269 SRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHV 328
Query: 301 AGSPTA----------PVHDESLVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAA 350
P PV D P + G D + L L P T Y TV +
Sbjct: 329 QWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQ--LTDLVPNTEYAVTVQAVLH 386
Query: 351 NGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWK-VSDNESSSNYTYKIHVAGETDS 409
+ T E + D+ +++ +++ + W+ V YK E D
Sbjct: 387 DLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYK---TPEEDV 443
Query: 410 SNLNV--SEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPV-SDFRVTVVS 466
+ V SE + L S T Y ++V V + E P Q T PVP ++ ++T V+
Sbjct: 444 KEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVT 503
Query: 467 TTEIGLAWSSHDAESFQMHITQEGAGNS-RVEITTN---QSIIIGGLFPGTKYCFEIVPK 522
+ W ++ IT G+S ++E N +++ L P T Y I
Sbjct: 504 SEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAI 563
Query: 523 GPNGTE-----GASRTV 534
P+ +E G+ RT+
Sbjct: 564 YPDESESDDLIGSERTL 580
Score = 35.8 bits (81), Expect = 0.10
Identities = 54/237 (22%), Positives = 84/237 (35%), Gaps = 10/237 (4%)
Query: 308 VHDESLVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAI 367
++ ++ P+D + R V+L L+P T Y TV + +G G + +
Sbjct: 894 IYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGH---LTGNGRTV 950
Query: 368 QVFDVTAVNISATSLTLIWKVSDNESSSNYTYKI--HVAGETDSSNLNVSEPRA-VIPGL 424
+ ++IS T D S YKI G + V E + + L
Sbjct: 951 GLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNL 1010
Query: 425 RSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQM 484
ST Y++ V P Q T + V+D + + + WS H A +
Sbjct: 1011 NPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYR 1070
Query: 485 HITQEGAGNSRVEIT---TNQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRT 538
G EIT + S GL P T Y + + PN EG +V T
Sbjct: 1071 LKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPN-LEGPGVSVKEHT 1126
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 43.5 bits (101), Expect = 5e-04
Identities = 38/145 (26%), Positives = 59/145 (40%), Gaps = 5/145 (3%)
Query: 314 VGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVT 373
VG +P T L L P T Y+ VY+Q +G P + T + V D+
Sbjct: 2153 VGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLS-VPLTDQGTTLYLNVTDLK 2211
Query: 374 AVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNV--SEPRAVIPGLRSSTFYN 431
I + + W S + ++++Y K+ A T + V SE GL T Y
Sbjct: 2212 TYQIGWDTFCVKW--SPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYG 2269
Query: 432 ITVCPVLGDIEGTPGFLQVHTPPVP 456
+TV ++EG ++ HT P
Sbjct: 2270 VTVFVQTPNLEGPGVSVKEHTTVKP 2294
Score = 42.4 bits (98), Expect = 0.001
Identities = 72/317 (22%), Positives = 118/317 (37%), Gaps = 40/317 (12%)
Query: 253 SRLQVN--ISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGL----------DASNTERSR 300
SR++ + + LKP +Y +N Y + ++ GTE L D T
Sbjct: 1433 SRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHV 1492
Query: 301 AGSPTA----------PVHDESLVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAA 350
P PV D P + G D + L L P T Y TV +
Sbjct: 1493 QWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQ--LTDLVPNTEYAVTVQAVLH 1550
Query: 351 NGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWK-VSDNESSSNYTYKIHVAGETDS 409
+ T E + D+ +++ +++ + W+ V YK E D
Sbjct: 1551 DLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYK---TPEEDV 1607
Query: 410 SNLNV--SEPRAVIPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPV-SDFRVTVVS 466
+ V SE + L S T Y ++V V + E P Q T PVP ++ ++T V+
Sbjct: 1608 KEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVT 1667
Query: 467 TTEIGLAWSSHDAESFQMHITQEGAGNS-RVEITTN---QSIIIGGLFPGTKYCFEIVPK 522
+ W ++ IT G+S ++E N +++ L P T Y I
Sbjct: 1668 SEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAI 1727
Query: 523 GPNGTE-----GASRTV 534
P+ +E G+ RT+
Sbjct: 1728 YPDESESDDLIGSERTL 1744
Score = 36.6 bits (83), Expect = 0.060
Identities = 74/355 (20%), Positives = 133/355 (37%), Gaps = 64/355 (18%)
Query: 139 WKSNDTAASE--YKYVVKHK-MENEKTITVVHQPWCN---ITGLRPATSYVFSIT----- 187
+K+N + A E + Y + +K + +TVV ++ L+P T Y+ ++T
Sbjct: 648 FKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYED 707
Query: 188 ----PGIGNETW----GDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNGTA-SCRV 238
P G ET G PR +KV E ++W+ G R+
Sbjct: 708 GFSIPLAGEETTEEVKGAPRNLKVTDETTD------------SFKITWTQAPGRVLRYRI 755
Query: 239 LLESIG---SHEELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDA-- 293
+ + S E T ++ + + L P +Y ++ + + G PL +
Sbjct: 756 IYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVS-VIPEYFSGPGTPLTGNAATEEVR 814
Query: 294 SNTERSRAGSPT----------APVHDESLVGPVDPSSGQQSRD-------TEVLLVGLE 336
N R PT AP + + P +G ++++ T +L GL+
Sbjct: 815 GNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLK 874
Query: 337 PGTRYNATVYSQAANGTE----GQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDNE 392
GT+Y +V + A+G G+ +E R + D+ +I+ TS+ W +
Sbjct: 875 EGTQYALSVTALYASGAGDALFGEGTTLEERGSPQ---DLVTKDITDTSIGAYWTSAPGM 931
Query: 393 SSSNYTYKIHVAGETDSSNLNVSEP--RAVIPGLRSSTFYNITVCPVLGDIEGTP 445
+ + D+ N+ E +I L+ T Y I+V EG P
Sbjct: 932 VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEP 986
Score = 35.8 bits (81), Expect = 0.10
Identities = 54/237 (22%), Positives = 84/237 (35%), Gaps = 10/237 (4%)
Query: 308 VHDESLVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAI 367
++ ++ P+D + R V+L L+P T Y TV + +G G + +
Sbjct: 2058 IYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGH---LTGNGRTV 2114
Query: 368 QVFDVTAVNISATSLTLIWKVSDNESSSNYTYKI--HVAGETDSSNLNVSEPRA-VIPGL 424
+ ++IS T D S YKI G + V E + + L
Sbjct: 2115 GLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNL 2174
Query: 425 RSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAESFQM 484
ST Y++ V P Q T + V+D + + + WS H A +
Sbjct: 2175 NPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYR 2234
Query: 485 HITQEGAGNSRVEIT---TNQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRT 538
G EIT + S GL P T Y + + PN EG +V T
Sbjct: 2235 LKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPN-LEGPGVSVKEHT 2290
Score = 30.4 bits (67), Expect = 4.3
Identities = 38/173 (21%), Positives = 65/173 (37%), Gaps = 19/173 (10%)
Query: 319 PSSGQQSRDTEV-------LLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQ--V 369
P +G +SR+ L L P T+Y +V + +G G P T ++
Sbjct: 759 PVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGP-GTPLTGNAATEEVRGNP 817
Query: 370 FDVTAVNISATSLTLIWKVSDNESSSNY-TYKIHVAGETDSSNLNVSEPRAVIPGLRSST 428
D+ + + +++ L W + + TY GET + V+ GL+ T
Sbjct: 818 RDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGT 877
Query: 429 FYNITVCPVLGDIEGTPGF-----LQVHTPPVPVSDFRVTVVSTTEIGLAWSS 476
Y ++V + G F L+ P D ++ T IG W+S
Sbjct: 878 QYALSVTALYASGAGDALFGEGTTLEERGSP---QDLVTKDITDTSIGAYWTS 927
>gi|20665034 tenascin XB isoform 2 [Homo sapiens]
Length = 673
Score = 41.6 bits (96), Expect = 0.002
Identities = 92/372 (24%), Positives = 136/372 (36%), Gaps = 80/372 (21%)
Query: 225 LSWSNGNGTASCRVLL--ESIGSHEELTQDS-RLQVNISGLKPGVQYNINPYLLQSNKTK 281
LSWS G V+ ++ G + L D + ++ ISGL+P Y Y L K
Sbjct: 3 LSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRL 62
Query: 282 GDPLGTEG--GLDASN--TERSRAGSPTAPVHD----------ESLVGPVD--------P 319
G PL EG GL + +E SR V D E+ G D P
Sbjct: 63 G-PLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVP 121
Query: 320 SSGQQSRDTEVLLVG--LEPGTRYNA--------TVYSQAANGTEGQPQAIEFRTNAIQV 369
S LL + PGTR++A T+YS G G +A + A +
Sbjct: 122 SPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTL 181
Query: 370 F-------DVTAVNISATSLTLIWKVSDNESSS-NYTYKIHVAGETDSSNLNVSEPRAVI 421
D+ I TS + W + + S +Y++ GE S ++ +
Sbjct: 182 SPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKL 241
Query: 422 PGLRSSTFYNITVCPVLGDIEGTP--GFLQVHTPPVPVSDFRVTVVSTTE--IGLAWS-- 475
GL Y +TV V G E P GFL VP ++ ++ TE L W
Sbjct: 242 QGLIPGARYEVTVVSVRGFEESEPLTGFLTT----VPDGPTQLRALNLTEGFAVLHWKPP 297
Query: 476 SHDAESFQMHITQEGAGNSRVE--------------ITTNQSIIIGGLFPGTKYCFEIVP 521
+ +++ + +T GA + E + TN + + GL
Sbjct: 298 QNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGL------------ 345
Query: 522 KGPNGTEGASRT 533
+GPN T AS T
Sbjct: 346 RGPNLTSPASIT 357
Score = 30.8 bits (68), Expect = 3.3
Identities = 47/194 (24%), Positives = 67/194 (34%), Gaps = 18/194 (9%)
Query: 332 LVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNISATSLTLIWKVSDN 391
L GL PG RY TV S E +P T + A+N++ L WK N
Sbjct: 241 LQGLIPGARYEVTVVS-VRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQN 299
Query: 392 ESSSNYTYKIHVAGETDSSNLNVSEPRAVIP----GLRSSTFYNITVCPVLGDIEGTPGF 447
TY + V + L P + + L T Y TV + G +P
Sbjct: 300 PVD---TYDVQVTA-PGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPAS 355
Query: 448 LQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAE--SFQMHITQEGAGNSRV----EITTN 501
+ T D V+ L W+ + + G N + IT++
Sbjct: 356 ITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSH 415
Query: 502 QSIIIGGLFPGTKY 515
Q + GLFP T Y
Sbjct: 416 QLL---GLFPSTSY 426
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 40.8 bits (94), Expect = 0.003
Identities = 34/153 (22%), Positives = 61/153 (39%), Gaps = 10/153 (6%)
Query: 328 TEVLLVGLEPGTRYNATVYSQAANGTEGQPQAIEFRTNAIQVFDVTAVNI-----SATSL 382
T V + LEP Y TV +A NG G + FRT ++ + + S TSL
Sbjct: 395 TSVTVSDLEPHMNYTFTV--EARNGVSGLVTSRSFRTASVSINQTEPPKVRLEGRSTTSL 452
Query: 383 TLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPR---AVIPGLRSSTFYNITVCPVLG 439
++ W + + S + Y++ + DS++ NV + L T Y + V +
Sbjct: 453 SVSWSIPPPQQSRVWKYEVTYRKKGDSNSYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQ 512
Query: 440 DIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGL 472
+ +G + P + V+ +G+
Sbjct: 513 EGQGAGSKVHEFQTLSPEGSGNLAVIGGVAVGV 545
>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
Length = 1008
Score = 40.8 bits (94), Expect = 0.003
Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 17/94 (18%)
Query: 116 STGPSPVFD---IKAVSISPTNVILTWK---------SNDTAASEYKYVVKHKMENEKTI 163
STGP ++ I+ + P +V L+W+ +NDT EY+ K ++E+T
Sbjct: 448 STGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDT---EYEIRYYEKGQSEQTY 504
Query: 164 TVVHQ--PWCNITGLRPATSYVFSITPGIGNETW 195
++V P +T L+PAT YVF I +W
Sbjct: 505 SMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSW 538
>gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo
sapiens]
Length = 800
Score = 40.0 bits (92), Expect = 0.005
Identities = 42/147 (28%), Positives = 51/147 (34%), Gaps = 38/147 (25%)
Query: 1 MKPAAREARLPPRSPGLRWALPLLLLLLRLGQILCAGGTP----------SPIPDPSVAT 50
+ PA RLPPRSP RLG+ G P SP P P
Sbjct: 287 LPPAGHTLRLPPRSPP------------RLGRAPHFNGPPAHPGPGRPSTSPCPLPPSLL 334
Query: 51 VATGENGITQ-ISSTAESFHKQNGTGTPQVE--TNTSEDGESSGAND------------- 94
E+G + S AE + G G P VE + GE +G +
Sbjct: 335 CLWVESGTPRGRQSLAEGVKRDGGQGLPDVEGAPDMGSSGEGAGLEEGSPLRRERAWPPP 394
Query: 95 SLRTPEQGSNGTDGASQKTPSSTGPSP 121
SLRTP G G + GPSP
Sbjct: 395 SLRTPTPGLTEGGGTGLPSKQRRGPSP 421
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,786,406
Number of Sequences: 37866
Number of extensions: 1135551
Number of successful extensions: 4078
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 120
Number of HSP's that attempted gapping in prelim test: 3187
Number of HSP's gapped (non-prelim): 802
length of query: 539
length of database: 18,247,518
effective HSP length: 107
effective length of query: 432
effective length of database: 14,195,856
effective search space: 6132609792
effective search space used: 6132609792
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.