Search of human proteins with 148612803

Search of human proteins with 148612803

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148612803 keratin 6 irs4 [Homo sapiens]
         (529 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148612803 keratin 6 irs4 [Homo sapiens]                           1024   0.0  
gi|28173564 keratin 73 [Homo sapiens]                                 725   0.0  
gi|15618995 keratin 71 [Homo sapiens]                                 722   0.0  
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       682   0.0  
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      682   0.0  
gi|119395754 keratin 5 [Homo sapiens]                                 568   e-162
gi|109255249 keratin 4 [Homo sapiens]                                 565   e-161
gi|5031839 keratin 6A [Homo sapiens]                                  560   e-159
gi|155969697 keratin 6C [Homo sapiens]                                558   e-159
gi|119703753 keratin 6B [Homo sapiens]                                558   e-159
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      557   e-158
gi|153791158 keratin 75 [Homo sapiens]                                551   e-157
gi|109148552 keratin 3 [Homo sapiens]                                 547   e-155
gi|153791670 keratin 76 [Homo sapiens]                                540   e-153
gi|119395750 keratin 1 [Homo sapiens]                                 536   e-152
gi|47132620 keratin 2 [Homo sapiens]                                  529   e-150
gi|194018511 keratin 77 [Homo sapiens]                                518   e-147
gi|32567786 keratin 6L [Homo sapiens]                                 514   e-146
gi|89357932 keratin 5b [Homo sapiens]                                 456   e-128
gi|67782365 keratin 7 [Homo sapiens]                                  441   e-124
gi|4504919 keratin 8 [Homo sapiens]                                   439   e-123
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    427   e-119
gi|27477127 keratin 82 [Homo sapiens]                                 404   e-112
gi|4504935 keratin 85 [Homo sapiens]                                  403   e-112
gi|169790841 keratin 83 [Homo sapiens]                                381   e-106
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   379   e-105
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   379   e-105
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   379   e-105
gi|14318422 keratin 86 [Homo sapiens]                                 379   e-105
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   379   e-105

>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score = 1024 bits (2648), Expect = 0.0
 Identities = 529/529 (100%), Positives = 529/529 (100%)

Query: 1   MSRQLNIKSSGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRIS 60
           MSRQLNIKSSGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRIS
Sbjct: 1   MSRQLNIKSSGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRIS 60

Query: 61  FNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKS 120
           FNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKS
Sbjct: 61  FNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKS 120

Query: 121 LLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDL 180
           LLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDL
Sbjct: 121 LLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDL 180

Query: 181 NNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTA 240
           NNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTA
Sbjct: 181 NNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTA 240

Query: 241 ENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMD 300
           ENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMD
Sbjct: 241 ENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMD 300

Query: 301 NNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVE 360
           NNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVE
Sbjct: 301 NNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVE 360

Query: 361 LNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELAR 420
           LNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELAR
Sbjct: 361 LNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELAR 420

Query: 421 MLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAG 480
           MLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAG
Sbjct: 421 MLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAG 480

Query: 481 VDLGASAVAGSSGSTQSGQTKTTEARGGDLKDTQGKSTPASIPARKATR 529
           VDLGASAVAGSSGSTQSGQTKTTEARGGDLKDTQGKSTPASIPARKATR
Sbjct: 481 VDLGASAVAGSSGSTQSGQTKTTEARGGDLKDTQGKSTPASIPARKATR 529


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score =  725 bits (1871), Expect = 0.0
 Identities = 397/549 (72%), Positives = 438/549 (79%), Gaps = 29/549 (5%)

Query: 1   MSRQLNIKS-SGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRI 59
           MSRQ   KS +  KG FS  SAV+   + GS +SY A G+G   GF SRSLYSLGG R I
Sbjct: 1   MSRQFTYKSGAAAKGGFSGCSAVL---SGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSI 57

Query: 60  SFNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNK 119
           SFNVA G   AGGYGF      G GRASGFAGSMFGSVALG  C S+CPPGGIHQVT+NK
Sbjct: 58  SFNVASGSGWAGGYGF------GRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINK 111

Query: 120 SLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLD 179
           SLLAPLNVELDPEIQKVRAQEREQIKVLN+KFASFIDKVRFLEQQNQVLETKWELLQQLD
Sbjct: 112 SLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLD 171

Query: 180 LNNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTT 239
           LNNCK NLEPILEGYISNLRKQLETLSGDRVRLDSELRS+R++VEDYKKRYE EIN+RTT
Sbjct: 172 LNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTT 231

Query: 240 AENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSM 299
           AENEFVVLKKD DAAY  KVELQAKVD+LD EIKF KCLY+ E AQIQ+H S+TS+ILSM
Sbjct: 232 AENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSM 291

Query: 300 DNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMV 359
           DNNR+LDLDSIIAEVR  YEEIA KSKAEAEALYQTK QELQLAA RHGDDLKHT++E+ 
Sbjct: 292 DNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEIS 351

Query: 360 ELNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELA 419
           EL RLIQR+R EI +VKKQ A+LETAIADAEQRGD ALKDA+AKLDELEGAL QAKEELA
Sbjct: 352 ELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELA 411

Query: 420 RMLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSS---------- 469
           RMLREYQEL+S+KL+LD+EIATYRKLLEGEECRMSGE  +SVSISVI+SS          
Sbjct: 412 RMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAG 471

Query: 470 -------SYSYHHPSSAG--VDLGASAVAGSSGSTQSGQTKTTEARGGDLKDTQGKSTPA 520
                  +Y Y   S +G    L    V GS   +  G+ +T      + +D+QGK+   
Sbjct: 472 FGFSNAGTYGYWPSSVSGGYSMLPGGCVTGSGNCSPRGEARTRLGSASEFRDSQGKTLAL 531

Query: 521 SIPARKATR 529
           S P +K  R
Sbjct: 532 SSPTKKTMR 540


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  722 bits (1863), Expect = 0.0
 Identities = 393/534 (73%), Positives = 437/534 (81%), Gaps = 16/534 (2%)

Query: 1   MSRQLNIKS-SGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRI 59
           MSRQ   KS +  KG FS  SAV+   + GS +S+ A  +G   GFGSRSLYSLGG R  
Sbjct: 1   MSRQFTCKSGAAAKGGFSGCSAVL---SGGSSSSFRAGSKGLSGGFGSRSLYSLGGVR-- 55

Query: 60  SFNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNK 119
           S NVA G  ++GGYGF      G GRASGFAGSMFGSVALGP C +VCPPGGIHQVTVN+
Sbjct: 56  SLNVASGSGKSGGYGF------GRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNE 109

Query: 120 SLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLD 179
           SLLAPLNVELDPEIQKVRAQEREQIK LN+KFASFIDKVRFLEQQNQVLETKWELLQQLD
Sbjct: 110 SLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLD 169

Query: 180 LNNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTT 239
           LNNCK NLEPILEGYISNLRKQLETLSGDRVRLDSELR++RD+VEDYKKRYE EIN+RT 
Sbjct: 170 LNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTA 229

Query: 240 AENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSM 299
           AENEFV+LKKD DAAYA KVELQAKV+S+D+EIKF +CL++AEI QIQ+H S+ SVILSM
Sbjct: 230 AENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSM 289

Query: 300 DNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMV 359
           DNNR+LDLDSII EVR  YEEIALKSKAEAEALYQTK QELQLAA RHGDDLK+T++E+ 
Sbjct: 290 DNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEIS 349

Query: 360 ELNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELA 419
           EL RLIQRIR EI NVKKQ ++LETAIADAEQRGDNALKDA+AKLDELEGALHQAKEELA
Sbjct: 350 ELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELA 409

Query: 420 RMLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSS----YSYHH 475
           RMLREYQELMSLKLALDMEIATYRKLLE EECRMSGE PS VSIS+ISS+S    Y +  
Sbjct: 410 RMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGSVYGFRP 469

Query: 476 PSSAGVDLGASAVAGSSGSTQSGQTKTTEARGGDLKDTQGKSTPASIPARKATR 529
              +G  +  S+   S   +  G    +     D KDT GK +  S P++K +R
Sbjct: 470 SMVSGGYVANSSNCISGVCSVRGGEGRSRGSANDYKDTLGKGSSLSAPSKKTSR 523


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  682 bits (1761), Expect = 0.0
 Identities = 373/529 (70%), Positives = 418/529 (79%), Gaps = 18/529 (3%)

Query: 1   MSRQLNIKSSGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRIS 60
           MSRQL     G++  FS  SAV+      S AS+ A  +G+ A FGS+SL  LGG+R ++
Sbjct: 1   MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGS-ASFGSKSLSCLGGSRSLA 59

Query: 61  FNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKS 120
            + A              +  GGGR  GF G+ FGS  LGP C SVCPPGGI QVTVNKS
Sbjct: 60  LSAA--------------ARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKS 105

Query: 121 LLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDL 180
           LLAPLNVE+DPEIQ+VRAQEREQIK LN+KFASFIDKVRFLEQQNQVLETKW LLQQLDL
Sbjct: 106 LLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDL 165

Query: 181 NNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTA 240
           NNC+KNLEPI EGYISNL+KQLE LSGD VRLDSELR+M+DLVEDYKKRYEVEINRRT A
Sbjct: 166 NNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAA 225

Query: 241 ENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMD 300
           ENEFVVLKKD DAAY  KVELQAKVDSL  EIKF KCLY+ EI QIQ+H S+TS++LSMD
Sbjct: 226 ENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMD 285

Query: 301 NNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVE 360
           NNRDLDLDSIIAEVR  YEEIALKSKAEAE LYQTKIQELQ+ A +HGDDLK T++E+ E
Sbjct: 286 NNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISE 345

Query: 361 LNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELAR 420
           LNRLIQRIR EIGNVKKQ A LETAIADAEQRGD ALKDA+AKLDELEGALHQAKEELAR
Sbjct: 346 LNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELAR 405

Query: 421 MLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAG 480
           MLREYQEL+SLKLALDMEIATYRKLLE EECRMSGE P+SVSISVISS++        AG
Sbjct: 406 MLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAG---AGGAG 462

Query: 481 VDLGASAVAGSSGSTQSGQTKTTEARGGDLKDTQGKSTPASIPARKATR 529
             +G  A +  S  T +   KT  + G +LKD   K++ +S   +KA+R
Sbjct: 463 FSMGFGASSSYSYKTAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR 511


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  682 bits (1761), Expect = 0.0
 Identities = 373/529 (70%), Positives = 418/529 (79%), Gaps = 18/529 (3%)

Query: 1   MSRQLNIKSSGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRIS 60
           MSRQL     G++  FS  SAV+      S AS+ A  +G+ A FGS+SL  LGG+R ++
Sbjct: 1   MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGS-ASFGSKSLSCLGGSRSLA 59

Query: 61  FNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKS 120
            + A              +  GGGR  GF G+ FGS  LGP C SVCPPGGI QVTVNKS
Sbjct: 60  LSAA--------------ARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKS 105

Query: 121 LLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDL 180
           LLAPLNVE+DPEIQ+VRAQEREQIK LN+KFASFIDKVRFLEQQNQVLETKW LLQQLDL
Sbjct: 106 LLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDL 165

Query: 181 NNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTA 240
           NNC+KNLEPI EGYISNL+KQLE LSGD VRLDSELR+M+DLVEDYKKRYEVEINRRT A
Sbjct: 166 NNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAA 225

Query: 241 ENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMD 300
           ENEFVVLKKD DAAY  KVELQAKVDSL  EIKF KCLY+ EI QIQ+H S+TS++LSMD
Sbjct: 226 ENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMD 285

Query: 301 NNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVE 360
           NNRDLDLDSIIAEVR  YEEIALKSKAEAE LYQTKIQELQ+ A +HGDDLK T++E+ E
Sbjct: 286 NNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISE 345

Query: 361 LNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELAR 420
           LNRLIQRIR EIGNVKKQ A LETAIADAEQRGD ALKDA+AKLDELEGALHQAKEELAR
Sbjct: 346 LNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELAR 405

Query: 421 MLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAG 480
           MLREYQEL+SLKLALDMEIATYRKLLE EECRMSGE P+SVSISVISS++        AG
Sbjct: 406 MLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAG---AGGAG 462

Query: 481 VDLGASAVAGSSGSTQSGQTKTTEARGGDLKDTQGKSTPASIPARKATR 529
             +G  A +  S  T +   KT  + G +LKD   K++ +S   +KA+R
Sbjct: 463 FSMGFGASSSYSYKTAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR 511


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  568 bits (1463), Expect = e-162
 Identities = 312/546 (57%), Positives = 391/546 (71%), Gaps = 39/546 (7%)

Query: 1   MSRQLNIK-SSGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFG------------- 46
           MSRQ ++   SG   +FS  SA+ P  +  S  S   +G G G GFG             
Sbjct: 1   MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGY 60

Query: 47  -SRSLYSLGGNRRISFNVAGGGVR-------AGGYGFRPGSG----YGGGRASGFA---G 91
            SRSLY+LGG++RIS + +GG  R        GGYGF  G+G    +GGG   GF    G
Sbjct: 61  GSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGG 120

Query: 92  SMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLNDKF 151
           + FG    GP    VCPPGGI +VTVN+SLL PLN+++DP IQ+VR +EREQIK LN+KF
Sbjct: 121 AGFGGGFGGPG-FPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKF 179

Query: 152 ASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLSGDRVR 211
           ASFIDKVRFLEQQN+VL+TKW LLQ+      ++NLEP+ E YI+NLR+QL+++ G+R R
Sbjct: 180 ASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGR 239

Query: 212 LDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLDKE 271
           LDSELR+M+DLVED+K +YE EIN+RTTAENEFV+LKKD DAAY  KVEL+AKVD+L  E
Sbjct: 240 LDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDE 299

Query: 272 IKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEAEA 331
           I F+K  +DAE++Q+QTH S+TSV+LSMDNNR+LDLDSIIAEV+  YEEIA +S+ EAE+
Sbjct: 300 INFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAES 359

Query: 332 LYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADAEQ 391
            YQTK +ELQ  A RHGDDL++T+ E+ E+NR+IQR+R EI NVKKQ A+L+ AIADAEQ
Sbjct: 360 WYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQ 419

Query: 392 RGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGEEC 451
           RG+ ALKDA+ KL ELE AL +AK+++AR+LREYQELM+ KLALD+EIATYRKLLEGEEC
Sbjct: 420 RGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEEC 479

Query: 452 RMSGENPSSVSISVISSSSYSYHHPSSA---------GVDLGASAVAGSSGSTQSGQTKT 502
           R+SGE    V+ISV++SS  S +   S          G  LG     GSSGS  S  +  
Sbjct: 480 RLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGG 539

Query: 503 TEARGG 508
               GG
Sbjct: 540 VGLGGG 545



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 23/69 (33%), Positives = 26/69 (37%), Gaps = 3/69 (4%)

Query: 29  GSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVRAGGYGFRPGSGYGGGRASG 88
           G L      G G G   GS   Y    +  +     GGG+  GG GF   SG G G   G
Sbjct: 510 GGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVGL---GGGLSVGGSGFSASSGRGLGVGFG 566

Query: 89  FAGSMFGSV 97
             G    SV
Sbjct: 567 SGGGSSSSV 575


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  565 bits (1455), Expect = e-161
 Identities = 309/495 (62%), Positives = 375/495 (75%), Gaps = 20/495 (4%)

Query: 11  GDKGNFSVHSAVV---PRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGG- 66
           G    FS  SA+V    R A  S++    AGR +  GFGSRSLY+L GN+ IS +VAG  
Sbjct: 84  GGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSR 143

Query: 67  -GVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPL 125
            G   GG G     G+GGG    F+G        G     VCP GGI +VT+N+SLL PL
Sbjct: 144 QGACFGGAGGFGTGGFGGGFGGSFSGK-------GGPGFPVCPAGGIQEVTINQSLLTPL 196

Query: 126 NVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKK 185
           +VE+DPEIQKVR +EREQIK+LN+KFASFIDKV+FLEQQN+VLETKW LLQQ       K
Sbjct: 197 HVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSK 256

Query: 186 NLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFV 245
           NLEP+ E Y+S LRKQL+TL  D+ RL SEL++M+D VED+K +YE EIN+RT AEN+FV
Sbjct: 257 NLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFV 316

Query: 246 VLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDL 305
           VLKKD DAAY  KVEL+AKVDSL+ EI FLK LYDAE++Q+QTH S+TSV+LSMDNNR+L
Sbjct: 317 VLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNL 376

Query: 306 DLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLI 365
           DLDSIIAEVR  YEEIA +SKAEAEALYQTK+Q+LQ++  +HGD+LK+T+SE+ ELNR+I
Sbjct: 377 DLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMI 436

Query: 366 QRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREY 425
           QR+R EI N+KKQ  +L+ ++ADAEQRG+NALKDA +K  ELE AL QAKEELARMLREY
Sbjct: 437 QRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREY 496

Query: 426 QELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVD--L 483
           QELMS+KLALD+EIATYRKLLEGEE RMSGE  S+VSISV+S S+      S+ G+   L
Sbjct: 497 QELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGST------STGGISGGL 550

Query: 484 GASAVAGSSGSTQSG 498
           G+ +  G S    SG
Sbjct: 551 GSGSGFGLSSGFGSG 565



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 14/34 (41%), Positives = 18/34 (52%)

Query: 63  VAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGS 96
           ++GG     G+G   G G G G   GF GS+ GS
Sbjct: 546 ISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGS 579



 Score = 29.3 bits (64), Expect = 9.3
 Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 3/40 (7%)

Query: 59  ISFNVAGGGVRAGGYGFRPGSGYGGGRASGF---AGSMFG 95
           +S +V  G    GG     GSG G G +SGF   +GS FG
Sbjct: 532 VSISVVSGSTSTGGISGGLGSGSGFGLSSGFGSGSGSGFG 571


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  560 bits (1442), Expect = e-159
 Identities = 317/554 (57%), Positives = 396/554 (71%), Gaps = 40/554 (7%)

Query: 10  SGDKGNFSVHSAVVP---RKAVGSLASYCAAGRGA------GAGFGSRSLYSLGGNRRIS 60
           S  +  FS +SA +P   R    S++   + G G       GAGFGSRSLY LGG++RIS
Sbjct: 12  SSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRIS 71

Query: 61  FNVAGGGVRA--GGYGFRPGSGYG-GGRASGF-----AGSMFG-------SVALGPACLS 105
               GGG  A  GGYG R G  YG GG  SGF     AG  FG       +   G     
Sbjct: 72  I---GGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFP 128

Query: 106 VCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQN 165
           VCPPGGI +VTVN+SLL PLN+++DP IQ+VRA+EREQIK LN+KFASFIDKVRFLEQQN
Sbjct: 129 VCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQN 188

Query: 166 QVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVED 225
           +VLETKW LLQ+      ++NLEP+ E YI+NLR+QL+++ G+R RLDSELR M+DLVED
Sbjct: 189 KVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVED 248

Query: 226 YKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQ 285
           +K +YE EIN+RT AENEFV LKKD DAAY  KVELQAK D+L  EI FL+ LYDAE++Q
Sbjct: 249 FKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQ 308

Query: 286 IQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAAS 345
           +QTH S+TSV+LSMDNNR+LDLDSIIAEV+  YEEIA +S+AEAE+ YQTK +ELQ+ A 
Sbjct: 309 MQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAG 368

Query: 346 RHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLD 405
           RHGDDL++T+ E+ E+NR+IQR+R EI +VKKQ A+L+ AIADAEQRG+ ALKDA+ KL+
Sbjct: 369 RHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLE 428

Query: 406 ELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISV 465
            LE AL +AK++LAR+L+EYQELM++KLALD+EIATYRKLLEGEECR++GE    V+ISV
Sbjct: 429 GLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISV 488

Query: 466 ISSSSYSYHHPSSAGVDLGASAVAGSSGSTQSG-------QTKTTEARGGDLKDTQG--- 515
           +  S+ S  +  ++GV  G     GSS S  SG        + +  A GG L    G   
Sbjct: 489 V-QSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGSS 547

Query: 516 --KSTPASIPARKA 527
             K T  S  +RK+
Sbjct: 548 TIKYTTTSSSSRKS 561


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  558 bits (1439), Expect = e-159
 Identities = 316/554 (57%), Positives = 396/554 (71%), Gaps = 40/554 (7%)

Query: 10  SGDKGNFSVHSAVVP---RKAVGSLASYCAAGRGA------GAGFGSRSLYSLGGNRRIS 60
           S  +  FS +SA +P   R    S++   + G G       GAGFGSRSLY LGG++RIS
Sbjct: 12  SSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRIS 71

Query: 61  FNVAGGGVRA--GGYGFRPGSGYG-GGRASGF-----AGSMFG-------SVALGPACLS 105
               GGG  A  GGYG R G  YG GG  SGF     AG  FG       +   G     
Sbjct: 72  I---GGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFP 128

Query: 106 VCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQN 165
           VCPPGGI +VTVN+SLL PLN+++DP IQ+VRA+EREQIK LN+KFASFIDKVRFLEQQN
Sbjct: 129 VCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQN 188

Query: 166 QVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVED 225
           +VL+TKW LLQ+      ++NLEP+ E YI+NLR+QL+++ G+R RLDSELR+M+DLVED
Sbjct: 189 KVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVED 248

Query: 226 YKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQ 285
            K +YE EIN+RT AENEFV LKKD DAAY  KVELQAK D+L  EI FL+ LYDAE++Q
Sbjct: 249 LKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQ 308

Query: 286 IQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAAS 345
           +QTH S+TSV+LSMDNNR+LDLDSIIAEV+  YEEIA +S+AEAE+ YQTK +ELQ+ A 
Sbjct: 309 MQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAG 368

Query: 346 RHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLD 405
           RHGDDL++T+ E+ E+NR+IQR+R EI +VKKQ ASL+ AIADAEQRG+ ALKDA+ KL+
Sbjct: 369 RHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMALKDAKNKLE 428

Query: 406 ELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISV 465
            LE AL +AK++LAR+L+EYQELM++KLALD+EIATYRKLLEGEECR++GE    V++SV
Sbjct: 429 GLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNVSV 488

Query: 466 ISSSSYSYHHPSSAGVDLGASAVAGSSGSTQSG-------QTKTTEARGGDLKDTQG--- 515
           +  S+ S  +  ++GV  G     GSS S  SG        + +  A GG L    G   
Sbjct: 489 V-QSTISSGYGGASGVGSGLGLGGGSSYSYGSGLGIGGGFSSSSGRAIGGGLSSVGGGSS 547

Query: 516 --KSTPASIPARKA 527
             K T  S  +RK+
Sbjct: 548 TIKYTTTSSSSRKS 561


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  558 bits (1439), Expect = e-159
 Identities = 316/554 (57%), Positives = 395/554 (71%), Gaps = 40/554 (7%)

Query: 10  SGDKGNFSVHSAVVP---RKAVGSLASYCAAGRGA------GAGFGSRSLYSLGGNRRIS 60
           S  +  FS +SA +P   R    S++   + G G       GAGFGSRSLY LGG++RIS
Sbjct: 12  SSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRIS 71

Query: 61  FNVAGGGVRA--GGYGFRPGSGYG-GGRASGF-----AGSMFG-------SVALGPACLS 105
               GGG  A  GGYG R G  YG GG  SGF     AG  FG       +   G     
Sbjct: 72  I---GGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFP 128

Query: 106 VCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQN 165
           VCPPGGI +VTVN+SLL PLN+++DP IQ+VRA+EREQIK LN+KFASFIDKVRFLEQQN
Sbjct: 129 VCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQN 188

Query: 166 QVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVED 225
           +VL+TKW LLQ+      ++NLEP+ E YI+NLR+QL+ + G+R RLDSELR+M+DLVED
Sbjct: 189 KVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVED 248

Query: 226 YKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQ 285
            K +YE EIN+RT AENEFV LKKD DAAY  KVELQAK D+L  EI FL+ LYDAE++Q
Sbjct: 249 LKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQ 308

Query: 286 IQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAAS 345
           +QTH S+TSV+LSMDNNR+LDLDSIIAEV+  YEEIA +S+AEAE+ YQTK +ELQ+ A 
Sbjct: 309 MQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQITAG 368

Query: 346 RHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLD 405
           RHGDDL++T+ E+ E+NR+IQR+R EI +VKKQ A+L+ AIADAEQRG+ ALKDA+ KL+
Sbjct: 369 RHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLE 428

Query: 406 ELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISV 465
            LE AL +AK++LAR+L+EYQELM++KLALD+EIATYRKLLEGEECR++GE    V+ISV
Sbjct: 429 GLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISV 488

Query: 466 ISSSSYSYHHPSSAGVDLGASAVAGSSGSTQSG-------QTKTTEARGGDLKDTQG--- 515
           +  S+ S  +  ++GV  G     GSS S  SG        + +  A GG L    G   
Sbjct: 489 V-QSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRATGGGLSSVGGGSS 547

Query: 516 --KSTPASIPARKA 527
             K T  S  +RK+
Sbjct: 548 TIKYTTTSSSSRKS 561


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  557 bits (1435), Expect = e-158
 Identities = 321/532 (60%), Positives = 368/532 (69%), Gaps = 66/532 (12%)

Query: 1   MSRQLNIKSSGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRIS 60
           MSRQL     G++  FS  SAV+      S AS+ A  +G+ A FGS+SL  LGG+R ++
Sbjct: 1   MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGS-ASFGSKSLSCLGGSRSLA 59

Query: 61  FNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKS 120
            + A              +  GGGR  GF G+ FGS  LGP C SVCPPGGI QVTVNKS
Sbjct: 60  LSAA--------------ARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKS 105

Query: 121 LLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDL 180
           LLAPLNVE+DPEIQ+VRAQEREQIK LN+KFASFIDKVRFLEQQNQVLETKW LLQQLDL
Sbjct: 106 LLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDL 165

Query: 181 NNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTA 240
           NNC+KNLEPI EGYISNL+KQLE LSGD VRLDSELR+M+DLVEDYKKRYEVEINRRT A
Sbjct: 166 NNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAA 225

Query: 241 ENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMD 300
           ENEFVVLKKD DAAY  KVELQAKVDSL  EIKF KCLY+ EI QIQ+H S+TS++LSMD
Sbjct: 226 ENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMD 285

Query: 301 NNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLA---ASRHGDDLKHTRSE 357
           NNRDLDLDSIIAEVR  YEEIALKSKAEAE LYQTK  +L+ A   A + GD        
Sbjct: 286 NNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKCADLETAIADAEQRGD-------- 337

Query: 358 MVELNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEE 417
                       C + + + +   LE A+                         HQAKEE
Sbjct: 338 ------------CALKDARAKLDELEGAL-------------------------HQAKEE 360

Query: 418 LARMLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPS 477
           LARMLREYQEL+SLKLALDMEIATYRKLLE EECRMSGE P+SVSISVISS++       
Sbjct: 361 LARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAG---AG 417

Query: 478 SAGVDLGASAVAGSSGSTQSGQTKTTEARGGDLKDTQGKSTPASIPARKATR 529
            AG  +G  A +  S  T +   KT  + G +LKD   K++ +S   +KA+R
Sbjct: 418 GAGFSMGFGASSSYSYKTAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR 469


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  551 bits (1421), Expect = e-157
 Identities = 303/542 (55%), Positives = 389/542 (71%), Gaps = 31/542 (5%)

Query: 1   MSRQLNIK-SSGDKGNFSVHSAVVPRKAVGSLASYC----AAGRG-------AGAGFGSR 48
           MSRQ +I   SG +  FS  SA+ P       +S      AAG G       AGA FGSR
Sbjct: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR 60

Query: 49  SLYSLGGNRRISFNVAGGGVRAG-------GYGFRPGSGYGGGRASGFAGSMFGSVALGP 101
           SLY+LGG +R+S N  G   R+G        +G   G GYGGG   GF+G  F       
Sbjct: 61  SLYNLGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSF------- 113

Query: 102 ACLSVCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFL 161
               VCPPGGI +VTVN+SLL PL++++DP IQ+VRA+EREQIK LN+KFASFIDKVRFL
Sbjct: 114 ---PVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFL 170

Query: 162 EQQNQVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRD 221
           EQQN+VLETKW LLQ+      ++NLEP+ + Y S LR+QLE+++ +R RL++ELR+M+D
Sbjct: 171 EQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQD 230

Query: 222 LVEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDA 281
           +VED+K RYE EIN+RT AENEFV LKKD DAAY  KVEL+AKV SL +EI F+  ++DA
Sbjct: 231 VVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDA 290

Query: 282 EIAQIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQ 341
           E++Q+QT   +TSV+LSMDNNR+LDLDSIIAEV+  YE+IA +S+AEAE+ YQTK +ELQ
Sbjct: 291 ELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQ 350

Query: 342 LAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQ 401
           + A RHGDDL++T+ E+ E+NR+IQR+R EI +VKKQ +SL+TAIADAEQRG+ ALKDA+
Sbjct: 351 VTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDAR 410

Query: 402 AKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSV 461
           AKL +LE AL +AK+++AR+LREYQELM++KLALD+EIATYRKLLEGEECR+SGE  S V
Sbjct: 411 AKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPV 470

Query: 462 SISVISSS-SYSYHHPSS-AGVDLGASAVAGSSGSTQSGQTKTTEARGGDLKDTQGKSTP 519
           +ISV++S+ S  Y   SS  G +LG    +G S +T  G +      G     T  +   
Sbjct: 471 NISVVTSTLSSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLG 530

Query: 520 AS 521
            S
Sbjct: 531 GS 532


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  547 bits (1409), Expect = e-155
 Identities = 319/569 (56%), Positives = 387/569 (68%), Gaps = 62/569 (10%)

Query: 1   MSRQLNIKSSGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGA--------GFGSRSLYS 52
           MSRQ +  S G    FS  SAVV   +  S  ++ + G G GA        GFGSRSLY+
Sbjct: 1   MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAH-SGGAGGGAYGFRSGAGGFGSRSLYN 59

Query: 53  LGGNRRISFNVAGGGVRAGG-------------YGFRPGSGYGGG--------------- 84
           LGGN+ IS +VA GG RAGG             YG   GSGYGGG               
Sbjct: 60  LGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGF 119

Query: 85  -RASGFAGS--------------MFGSVALGPACLSVCP--------PGGIHQVTVNKSL 121
             A GF G+                GS   G       P        PGGI +VT+N+SL
Sbjct: 120 GGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSL 179

Query: 122 LAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLN 181
           L PLNVE+DP+I +V+AQEREQIK LN+KFASFIDKVRFLEQQN+VLETKW LLQQ   +
Sbjct: 180 LQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTS 239

Query: 182 NCK--KNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTT 239
           +     NLEP+ E +I+ LR  L+ + G+R RLDSEL++M DLVED+KK+YE EIN+RT 
Sbjct: 240 SISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTA 299

Query: 240 AENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSM 299
           AENEFV LKKD D+AY  KVELQAKVD+L  EI FL+ LYDAE++Q+Q+H S+TSV+LSM
Sbjct: 300 AENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSM 359

Query: 300 DNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMV 359
           DNNR LDLDSIIAEVR  YE+IA +SKAEAEALYQTK+ ELQ  A RHGDDL++T+SE++
Sbjct: 360 DNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEII 419

Query: 360 ELNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELA 419
           ELNR+IQR+R EI  VKKQ A+L+TAIA+AEQ G+ ALKDA AKL EL+ AL QAK++LA
Sbjct: 420 ELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLA 479

Query: 420 RMLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSA 479
           R+LR+YQELM++KLALD+EIATYRKLLEGEE RMSGE PS+VSISV+SSS+ S       
Sbjct: 480 RLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYG 539

Query: 480 GVDLGASAVAGSSGSTQSGQTKTTEARGG 508
           G   G        G +  G + +   RGG
Sbjct: 540 GGYGGGMGGGLGGGFSAGGGSGSGFGRGG 568



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 7/89 (7%)

Query: 17  SVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVRAGGY--- 73
           +V  +VV      + A     G G G G G    +S GG     F   GGG   GG+   
Sbjct: 520 AVSISVVSSSTTSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGG 579

Query: 74  --GFRPGSGYG--GGRASGFAGSMFGSVA 98
             GF  GSG+G   G   G +G  F S +
Sbjct: 580 SSGFSGGSGFGSISGARYGVSGGGFSSAS 608


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  540 bits (1392), Expect = e-153
 Identities = 321/552 (58%), Positives = 389/552 (70%), Gaps = 58/552 (10%)

Query: 1   MSRQLNIKS-SGDKGNFSVHSAVVPRKA-VGSLASYCAAGRGA-----GAG-FGSRSLYS 52
           M+RQ+  KS SG    FS  SAVV   + +  +A    AG GA     GAG FGSRSLY+
Sbjct: 1   MNRQVCKKSFSGRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYN 60

Query: 53  LGGNRRISFNVAGGGVRAGGYGFRP-----------------GSGYGGGRA--SGFAG-- 91
           LG N+ IS +VA G  RAGG+G                    G G+GGGR   SGF G  
Sbjct: 61  LGSNKSISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAG 120

Query: 92  ------------------SMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVELDPEI 133
                             S  G    GP       PGGI +V VN+SLL PLNVE+DP+I
Sbjct: 121 GFGGAGGFGGPGVFGGPGSFGGPGGFGPGGF----PGGIQEVIVNQSLLQPLNVEIDPQI 176

Query: 134 QKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPILEG 193
            +V+AQEREQIK LN+KFASFIDKVRFLEQQN+VLETKWELLQQ    +   +LEP  E 
Sbjct: 177 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFES 236

Query: 194 YISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADA 253
           YIS L KQL++L G+R  L+ EL+SM+DLVED+KK+YE EIN+RT AENEFV LKKD DA
Sbjct: 237 YISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDA 296

Query: 254 AYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAE 313
           A+  KVELQAKVDSL  E+ FL+ LY+ E++Q+Q+HAS+TSV+LSMDNNR LDL SIIAE
Sbjct: 297 AFMNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAE 356

Query: 314 VRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCEIG 373
           VR  YEEIA +SK+EAEALYQTK+ ELQ  A RHGDDL++T+SE++ELNR+IQR+R EI 
Sbjct: 357 VRAQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIE 416

Query: 374 NVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKL 433
           NVKKQ A+L+TAIA+AEQRG+ ALKDA AKL +L+ AL +AK++LAR+LR+YQELM++KL
Sbjct: 417 NVKKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKL 476

Query: 434 ALDMEIATYRKLLEGEECRMSGENPSSVSISVISS-SSYSYHHPSSAGVDLGASA----- 487
           ALD+EIATYRKLLEGEECRMSGE  S+V ISV+S+ +S S    SS GV  G S      
Sbjct: 477 ALDVEIATYRKLLEGEECRMSGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGG 536

Query: 488 -VAGSSGSTQSG 498
              GSS S+ SG
Sbjct: 537 YKGGSSSSSSSG 548



 Score = 33.1 bits (74), Expect = 0.64
 Identities = 30/89 (33%), Positives = 37/89 (41%), Gaps = 10/89 (11%)

Query: 9   SSGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYS-------LGGNRRISF 61
           S G KG  S  S+     + GS + Y     G+  G GS   Y        LGG   IS 
Sbjct: 534 SGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGGAGSISV 593

Query: 62  NVAGGGVRAGGYGFRPGSGY---GGGRAS 87
           + +G G  +G      GSGY   GGG  S
Sbjct: 594 SHSGMGSSSGSIQTSGGSGYKSGGGGSTS 622



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 2/68 (2%)

Query: 30  SLASYCAAGRGAGAGFGSRSLYSLGGNRRI-SFNVAGGGVRAGGYGFRPGSGYGGGRASG 88
           S + Y  +G G+G+G+G  S  S GG     S+  +  G R GG G    S  G G +SG
Sbjct: 545 SSSGYGVSG-GSGSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGGAGSISVSHSGMGSSSG 603

Query: 89  FAGSMFGS 96
              +  GS
Sbjct: 604 SIQTSGGS 611


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  536 bits (1381), Expect = e-152
 Identities = 289/506 (57%), Positives = 363/506 (71%), Gaps = 31/506 (6%)

Query: 29  GSLASYCAAGRG---AGAGFGSRSLYSLGGNRRISFNVAGGGVRAGGYGFR--------- 76
           G   S C  G G   AG GFGSRSL +LGG++ IS +VA GG R  G+G           
Sbjct: 43  GGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGG 102

Query: 77  --PGSGYGGGR------------ASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKSLL 122
              G G+GGG               GF G  FG    G     VCPPGGI +VT+N+SLL
Sbjct: 103 GFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLL 162

Query: 123 APLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNN 182
            PLNVE+DPEIQKV+++EREQIK LN++FASFIDKVRFLEQQNQVL+TKWELLQQ+D + 
Sbjct: 163 QPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTST 222

Query: 183 CKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAEN 242
              NLEP  E +I+NLR++++ L  D+ RLDSEL++M+D+VEDY+ +YE EIN+RT AEN
Sbjct: 223 RTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAEN 282

Query: 243 EFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNN 302
           EFV +KKD D AY  KV+LQAK+D+L +EI FL  LY AE++Q+QT  SET+VILSMDNN
Sbjct: 283 EFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNN 342

Query: 303 RDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELN 362
           R LDLDSIIAEV+  YE+IA KSKAEAE+LYQ+K +ELQ+ A RHGD +++++ E+ ELN
Sbjct: 343 RSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELN 402

Query: 363 RLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARML 422
           R+IQR+R EI NVKKQ ++L+ +I+DAEQRG+NALKDA+ KL++LE AL QAKE+LAR+L
Sbjct: 403 RVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLL 462

Query: 423 REYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVD 482
           R+YQELM+ KLALD+EIATYR LLEGEE RMSGE   +VS+SV +S     H   S G  
Sbjct: 463 RDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTS-----HTTISGGGS 517

Query: 483 LGASAVAGSSGSTQSGQTKTTEARGG 508
            G       SG +  G    +   GG
Sbjct: 518 RGGGGGGYGSGGSSYGSGGGSYGSGG 543



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 30/75 (40%), Positives = 34/75 (45%), Gaps = 10/75 (13%)

Query: 29  GSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVRAGGY-------GFRPGSGY 81
           GS  S    G G G+     S Y  GG    S+   GGG   G Y       G+R GSG 
Sbjct: 537 GSYGSGGGGGGGRGSYGSGGSSYGSGGG---SYGSGGGGGGHGSYGSGSSSGGYRGGSGG 593

Query: 82  GGGRASGFAGSMFGS 96
           GGG +SG  GS  GS
Sbjct: 594 GGGGSSGGRGSGGGS 608



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 27/65 (41%), Positives = 28/65 (43%), Gaps = 7/65 (10%)

Query: 40  GAGAGFGSR-SLYSLGGNRRISFNVAGGGVRAGGYGFRPGSGYGGGRAS---GFAGSMFG 95
           G G G+GS  S Y  GG    S    GGG   G YG   GS YG G  S   G  G   G
Sbjct: 520 GGGGGYGSGGSSYGSGGGSYGSGGGGGGG--RGSYG-SGGSSYGSGGGSYGSGGGGGGHG 576

Query: 96  SVALG 100
           S   G
Sbjct: 577 SYGSG 581



 Score = 30.8 bits (68), Expect = 3.2
 Identities = 28/62 (45%), Positives = 31/62 (50%), Gaps = 7/62 (11%)

Query: 33  SYCAAGRGAGAG-FGSRSLYSLGGNRRISFNVAGGGVRAGGYGFRPGSGYG--GGRASGF 89
           SY + G G G G +GS S  S GG R  S    GGG  +GG G   GS  G  GGR S  
Sbjct: 565 SYGSGGGGGGHGSYGSGS--SSGGYRGGSGG--GGGGSSGGRGSGGGSSGGSIGGRGSSS 620

Query: 90  AG 91
            G
Sbjct: 621 GG 622


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  529 bits (1362), Expect = e-150
 Identities = 305/559 (54%), Positives = 385/559 (68%), Gaps = 49/559 (8%)

Query: 1   MSRQLNIKSSGDKGN------FSVHSAVVP---RKAVGSLASYCAAGRGAGA----GFGS 47
           MS Q++ KS G  G       FS  SAVV    R++  S +     G G G     GFGS
Sbjct: 1   MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGS 60

Query: 48  RSLYSLGGNRRISFNVAGGGV---RAGGYGFRPGS---------------------GYGG 83
           RSL  LGG + IS +VAGGG     AGG+G R G                      G+GG
Sbjct: 61  RSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGG 120

Query: 84  GRASGFAG-----SMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRA 138
           GR  GF G      + G    GP       PGGIH+V+VN+SLL PLNV++DPEIQ V+A
Sbjct: 121 GRFGGFGGPGGVGGLGGPGGFGPGGY----PGGIHEVSVNQSLLQPLNVKVDPEIQNVKA 176

Query: 139 QEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPILEGYISNL 198
           QEREQIK LN+KFASFIDKVRFLEQQNQVL+TKWELLQQ+++     NLEPI +GYI +L
Sbjct: 177 QEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSL 236

Query: 199 RKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVK 258
           ++ L+ L+ +R   +SEL +M+DLVEDYKK+YE EIN+RT AEN+FV LKKD D AY +K
Sbjct: 237 KRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIK 296

Query: 259 VELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAEVRMHY 318
           VELQ+KVD L++EI+FLK LYDAEI+QI    ++T+VILSMDN+R+LDLDSIIAEV+  Y
Sbjct: 297 VELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQY 356

Query: 319 EEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQ 378
           EEIA +SK EAEALY +K +ELQ+   RHGD LK  + E+ ELNR+IQR++ EI +VKKQ
Sbjct: 357 EEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQ 416

Query: 379 RASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLALDME 438
             +++ AIADAEQRG++ALKDA+ KL++LE AL QAKE+LAR+LR+YQELM++KLALD+E
Sbjct: 417 CKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVE 476

Query: 439 IATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLGASAVAGSSGSTQSG 498
           IATYRKLLEGEECRMSG+  S+V++SV SS+  S     +A    G S   GSS      
Sbjct: 477 IATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAA---FGGSGGRGSSSGGGYS 533

Query: 499 QTKTTEARGGDLKDTQGKS 517
              ++   GG    ++G S
Sbjct: 534 SGSSSYGSGGRQSGSRGGS 552



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 27/70 (38%), Positives = 34/70 (48%), Gaps = 7/70 (10%)

Query: 29  GSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVRAGGY------GFRPGSGYG 82
           GS      +G G G+G GS   Y  GG  +   +++GGG  +GG       G R GS  G
Sbjct: 551 GSGGGGSISGGGYGSGGGSGGRYGSGGGSK-GGSISGGGYGSGGGKHSSGGGSRGGSSSG 609

Query: 83  GGRASGFAGS 92
           GG  SG  GS
Sbjct: 610 GGYGSGGGGS 619



 Score = 37.7 bits (86), Expect = 0.026
 Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 15/103 (14%)

Query: 8   KSSGDKGN---FSVHSAVVPRKAVGSLASYCAAGRGAGAGFG---SRSLYSLGGNRRISF 61
           + SGD  +    SV S+ +        A   + GRG+ +G G     S Y  GG +  S 
Sbjct: 490 RMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSR 549

Query: 62  NVAGGG--VRAGGYGF------RPGSGYGGGRASGFAGSMFGS 96
             +GGG  +  GGYG       R GSG GG +    +G  +GS
Sbjct: 550 GGSGGGGSISGGGYGSGGGSGGRYGSG-GGSKGGSISGGGYGS 591



 Score = 32.7 bits (73), Expect = 0.84
 Identities = 30/92 (32%), Positives = 37/92 (40%), Gaps = 11/92 (11%)

Query: 20  SAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVR------AGGY 73
           S+ V      S  S   A + A  G G R   S GG    S +   GG +      +GG 
Sbjct: 496 SSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGG 555

Query: 74  GFRPGSGYG-----GGRASGFAGSMFGSVALG 100
           G   G GYG     GGR     GS  GS++ G
Sbjct: 556 GSISGGGYGSGGGSGGRYGSGGGSKGGSISGG 587



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 12/60 (20%)

Query: 37  AGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGS 96
           +G G G+G G  S  S GG+R       GG    GGYG     G G     G +G  FGS
Sbjct: 585 SGGGYGSGGGKHS--SGGGSR-------GGSSSGGGYG---SGGGGSSSVKGSSGEAFGS 632


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  518 bits (1335), Expect = e-147
 Identities = 276/489 (56%), Positives = 356/489 (72%), Gaps = 21/489 (4%)

Query: 42  GAGFGSRSLYSLGGNRRISFNVAG---------GGVRAGGYGFRPGSGYGGGRASGFAGS 92
           G GFGSRSLY+LGG+R IS N+ G         GGV  GG+G   G G G   A GF G 
Sbjct: 53  GRGFGSRSLYNLGGSRSISINLMGRSTSGFCQGGGV--GGFGGGRGFGVGSTGAGGFGGG 110

Query: 93  MFGSVALGPACLSV------CPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKV 146
            FG    G +   +      CPPGGI +VT+N+SLL PL++E+DPEIQ+++ QEREQI V
Sbjct: 111 GFGGAGFGTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMV 170

Query: 147 LNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLS 206
           LN+KFASFIDKVRFLEQQNQVL+TKWELLQQ++ +    NLEP+LE YI +LR+Q++ LS
Sbjct: 171 LNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLS 230

Query: 207 GDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVD 266
            +++R ++E+RSM+D+VEDYK +YE EIN+RT +EN+FVVLKKD DAAY  KV+L+++VD
Sbjct: 231 AEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVD 290

Query: 267 SLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSK 326
           +L  E+ FLK L+  E++Q+QTH S+T+VILSMDNNR LDLDSII  VR  YE IA +SK
Sbjct: 291 TLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSK 350

Query: 327 AEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAI 386
            EAEALYQTK QELQ+ A RHGDDLK+++ E+ ELNR +QR++ EI NVKKQ   +++ I
Sbjct: 351 DEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLI 410

Query: 387 ADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLL 446
           +DAE+RG+ AL+DA  KL +LE AL Q+KEELAR+LR+YQ ++ +KL+LD+EIATYR+LL
Sbjct: 411 SDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLL 470

Query: 447 EGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLGASAVAGSSGSTQSGQTKTTEAR 506
           EGEE RMSGE  S VSISV  +S  S +  +  G   G+    G SG    G       R
Sbjct: 471 EGEESRMSGELQSHVSISV-QNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGG---GRSYR 526

Query: 507 GGDLKDTQG 515
           GG  +   G
Sbjct: 527 GGGARGRSG 535



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 28/79 (35%), Positives = 33/79 (41%), Gaps = 11/79 (13%)

Query: 19  HSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVRA-GGYGFRP 77
           +S V      G   SY + G G G+G G       GG R    +  GGG R   G G+  
Sbjct: 491 NSQVSVNGGAGGGGSYGSGGYGGGSGGG------YGGGR----SYRGGGARGRSGGGYGS 540

Query: 78  GSGYGGGRASGFAGSMFGS 96
           G G GGG   G   S  GS
Sbjct: 541 GCGGGGGSYGGSGRSGRGS 559


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  514 bits (1325), Expect = e-146
 Identities = 284/494 (57%), Positives = 359/494 (72%), Gaps = 23/494 (4%)

Query: 10  SGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGG--- 66
           SG +   S  S  V R +     ++C  G G   GFGSRSLY+LGG++ IS +VAGG   
Sbjct: 25  SGSQARTSFSSVTVSRSSGSGGGAHCGPGTG---GFGSRSLYNLGGHKSISVSVAGGALL 81

Query: 67  GVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLN 126
           G   GG+GF       G RA  F G   G    GPAC    PPGGI +VTVN+SLL PL+
Sbjct: 82  GRALGGFGF-------GSRA--FMGQGAGRQTFGPAC----PPGGIQEVTVNQSLLTPLH 128

Query: 127 VELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQL--DLNNCK 184
           VE+DPEIQ+VR QEREQIK LN+KFASFIDKVRFLEQQN+VLETKW LLQ+   +L   +
Sbjct: 129 VEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTR 188

Query: 185 KNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEF 244
            NLEP+ E Y+ ++R  L+ L  +R RLDSELR+++DLVED+K +YE EIN+ T AENEF
Sbjct: 189 NNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEF 248

Query: 245 VVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRD 304
           VVLKKD DAAY  +++L  KV +L +EI FL+ LY+ E++Q+QTH S T+V+LSMDNNR+
Sbjct: 249 VVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRN 308

Query: 305 LDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRL 364
           LDLDSIIAEV+  YE IA +S+AEAEA YQTK +ELQ+ A +HGD+L+ T++E+ EL R 
Sbjct: 309 LDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRT 368

Query: 365 IQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLRE 424
           IQR++ E    KKQ   L+TAIA+AEQRG+ ALKDAQ KL +L+ ALHQAKE+L R+LR+
Sbjct: 369 IQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRD 428

Query: 425 YQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLG 484
           YQELM++KLALD+EIATYRKLLE EE RMSGE PS+VSISV  +S+        A    G
Sbjct: 429 YQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTTVC--GGGAASFGG 486

Query: 485 ASAVAGSSGSTQSG 498
             ++ GS G+T+ G
Sbjct: 487 GISLGGSGGATKGG 500


>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score =  456 bits (1173), Expect = e-128
 Identities = 259/494 (52%), Positives = 330/494 (66%), Gaps = 31/494 (6%)

Query: 16  FSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVRAGGYGF 75
           FS  SA   R    S   + + G     GF SRSL S GG    S               
Sbjct: 12  FSARSACSARSRGRSRGGFSSRG-----GFSSRSLNSFGGCLEGS--------------- 51

Query: 76  RPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVELDPEIQK 135
             GS +G G   G  G  FG  + GP  LS+CPPGGI +VT+N++LL PL +E+DP+ Q 
Sbjct: 52  -RGSTWGSG---GRLGVRFGEWSGGPG-LSLCPPGGIQEVTINQNLLTPLKIEIDPQFQV 106

Query: 136 VRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPILEGYI 195
           VR QE ++I+ LN++FASFIDKVRFLEQQN+VLETKW LLQQ  L+  ++ LEP+ E  +
Sbjct: 107 VRTQETQEIRTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACL 166

Query: 196 SNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADAAY 255
             LRKQLE L G+R  LD+EL++ RD  E+YK +YE E +RR T EN+FVVLKKD D  +
Sbjct: 167 DQLRKQLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVF 226

Query: 256 AVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAEVR 315
             K+EL+ K+++L + + FLK L + E+ Q+QT AS+TSV+LSMDNNR LD  SII EVR
Sbjct: 227 LSKMELEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVR 286

Query: 316 MHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNV 375
             YEEIA  SKAEAEALYQTK QELQ++A  HGD ++ T+ ++ +L++ IQR++ +  N+
Sbjct: 287 ARYEEIARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENL 346

Query: 376 KKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLAL 435
           KKQ ASL+ AI DAEQRG+ ALKDAQAK+DELE AL  AK+ LAR+L EYQEL S KL+L
Sbjct: 347 KKQNASLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSL 406

Query: 436 DMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLGASAVAG-SSGS 494
           D+EIATYR+LLEGEECRMSGE  S V+IS +  S+       S GV  G  +  G  SG 
Sbjct: 407 DVEIATYRRLLEGEECRMSGECTSQVTISSVGGSAV-----MSGGVGGGLGSTCGLGSGK 461

Query: 495 TQSGQTKTTEARGG 508
              G   T+   GG
Sbjct: 462 GSPGSCCTSIVTGG 475


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  441 bits (1135), Expect = e-124
 Identities = 246/448 (54%), Positives = 316/448 (70%), Gaps = 18/448 (4%)

Query: 45  FGSRSLYSLGGNRRISFNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACL 104
           F SRS    G   ++  + A    R GG G     G G  R      S +G    GP   
Sbjct: 10  FTSRSAAFSGRGAQVRLSSA----RPGGLGSSSLYGLGASRPRVAVRSAYG----GPV-- 59

Query: 105 SVCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQ 164
                 GI +VT+N+SLLAPL ++ DP +Q+VR +E EQIK LN+KFASFIDKVRFLEQQ
Sbjct: 60  ----GAGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQ 115

Query: 165 NQVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVE 224
           N++LETKW LLQ+       + L  I E  I+ LR QLE L  D  RL++ELRSM+D+VE
Sbjct: 116 NKLLETKWTLLQEQKSAKSSR-LPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVE 174

Query: 225 DYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIA 284
           D+K +YE EIN RT AENEFVVLKKD DAAY  KVEL+AKVD+L+ EI FL+ L + E+ 
Sbjct: 175 DFKNKYEDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELT 234

Query: 285 QIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAA 344
           ++Q+  S+TSV+LSMDN+R LDLD IIAEV+  YEE+A  S+AEAEA YQTK + LQ  A
Sbjct: 235 ELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQA 294

Query: 345 SRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKL 404
            +HGDDL++TR+E+ E+NR IQR++ EI N+K QRA LE AIA+AE+RG+ ALKDA+AK 
Sbjct: 295 GKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQ 354

Query: 405 DELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSIS 464
           +ELE AL + K+++AR LREYQELMS+KLALD+EIATYRKLLEGEE R++G+   +V+IS
Sbjct: 355 EELEAALQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNIS 414

Query: 465 VISSSSYSYHHPSSAGVDLGASAVAGSS 492
           V++S+  S    S  G+ L      GS+
Sbjct: 415 VMNSTGGS---SSGGGIGLTLGGTMGSN 439


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  439 bits (1130), Expect = e-123
 Identities = 258/493 (52%), Positives = 337/493 (68%), Gaps = 43/493 (8%)

Query: 33  SYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVRAGGYGFRPGSGYGGGRASGFAGS 92
           SY  +  G  A F SRS Y+ G   RIS   +    R G   FR G G G G ASG    
Sbjct: 9   SYKVSTSGPRA-FSSRS-YTSGPGSRIS---SSSFSRVGSSNFRGGLGGGYGGASGM--- 60

Query: 93  MFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLNDKFA 152
                            GGI  VTVN+SLL+PL +E+DP IQ VR QE+EQIK LN+KFA
Sbjct: 61  -----------------GGITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFA 103

Query: 153 SFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLSGDRVRL 212
           SFIDKVRFLEQQN++LETKW LLQQ      + N++ + E YI+NLR+QLETL  ++++L
Sbjct: 104 SFIDKVRFLEQQNKMLETKWSLLQQQ--KTARSNMDNMFESYINNLRRQLETLGQEKLKL 161

Query: 213 DSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLDKEI 272
           ++EL +M+ LVED+K +YE EIN+RT  ENEFV++KKD D AY  KVEL+++++ L  EI
Sbjct: 162 EAELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEI 221

Query: 273 KFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEAEAL 332
            FL+ LY+ EI ++Q+  S+TSV+LSMDN+R LD+DSIIAEV+  YE+IA +S+AEAE++
Sbjct: 222 NFLRQLYEEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESM 281

Query: 333 YQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADAEQR 392
           YQ K +ELQ  A +HGDDL+ T++E+ E+NR I R++ EI  +K QRASLE AIADAEQR
Sbjct: 282 YQIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQR 341

Query: 393 GDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGEECR 452
           G+ A+KDA AKL ELE AL +AK+++AR LREYQELM++KLALD+EIATYRKLLEGEE R
Sbjct: 342 GELAIKDANAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESR 401

Query: 453 M-SGENPSSVSISVIS------SSSY--------SYHHPSSAGVDLGASAVAGSSGSTQS 497
           + SG    S+     S      SS+Y        SY   SS G   G+S+ + +S S+++
Sbjct: 402 LESGMQNMSIHTKTTSGYAGGLSSAYGGLTSPGLSYSLGSSFGSGAGSSSFSRTS-SSRA 460

Query: 498 GQTKTTEARGGDL 510
              K  E R G L
Sbjct: 461 VVVKKIETRDGKL 473


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  427 bits (1098), Expect = e-119
 Identities = 267/557 (47%), Positives = 348/557 (62%), Gaps = 49/557 (8%)

Query: 3   RQLNIKSSGDKGNFSVHSAVVP----RKAVGSLASYCAAG-RGAGAGFGSRSLYSLG--- 54
           R   + S    GNFS  SA+ P    R    S++ +   G RG G+ FGSRS+ + G   
Sbjct: 4   RSYRVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGS-FGSRSVITFGSYS 62

Query: 55  ------GNRRISFNV---AGGGVRAG---GYGFRP--------GSGYGGGRASGFAGSMF 94
                 G+R I   V   AG G+  G   G G  P        G G G G   GF G  F
Sbjct: 63  PRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGF 122

Query: 95  GSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASF 154
           G   +G   +   P   I  VTVNKSLL PLN+E+DP  Q+V+  E+EQIK LN+KFASF
Sbjct: 123 G-YRVGGVGVPAAP--SITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASF 179

Query: 155 IDKVRFLEQQNQVLETKWELLQQLDLNNC-KKNLEPILEGYISNLRKQLETLSGDRVRLD 213
           IDKVRFLEQQN++LETKW  LQ+     C + NLEP+ E YI+NLR+QLE L  D+ RL 
Sbjct: 180 IDKVRFLEQQNKLLETKWSFLQE---QKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQ 236

Query: 214 SELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLDKEIK 273
           +E   ++D++E +KK+YE E+  R  AENEFV LKKD DAA+  K +L+A VD+L +EI 
Sbjct: 237 AERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEID 296

Query: 274 FLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALY 333
           FLK LY  EI  +Q+H SETSVI+ MDN+RDL+LD IIAEV+  YEE+A +S+A+AEA Y
Sbjct: 297 FLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWY 356

Query: 334 QTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADAEQRG 393
           QTK +E+Q+ A +H D+L++ R+E+ EL RLIQR++ EI + K QRA LE A+A+AEQ+G
Sbjct: 357 QTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQG 416

Query: 394 DNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGEECRM 453
           +  L DA+ KL +LE AL QAK+++AR L EYQELM+ KL LD+EIATYR+LLEGEE R+
Sbjct: 417 EATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRL 476

Query: 454 -SGENPSSVSISVISSSSYSYHHPSSAGVDL--------GASAVAGSSGSTQSGQTKTTE 504
             G  P ++S+S           P  AG  L        G+S+V  +SG   S       
Sbjct: 477 CEGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSLGG 536

Query: 505 AR----GGDLKDTQGKS 517
           AR     GDL  T  +S
Sbjct: 537 ARVAPATGDLLSTGTRS 553


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  404 bits (1037), Expect = e-112
 Identities = 230/483 (47%), Positives = 322/483 (66%), Gaps = 32/483 (6%)

Query: 15  NFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLG--GNRRISFNVAGGGVRAGG 72
           +FS +SAV+PR     + ++ A  +G     G R L +LG  G+R +  NV  G  R   
Sbjct: 16  SFSSYSAVMPR-----MVTHYAVSKGPCRPGGGRGLRALGCLGSRSLC-NVGFGRPRVAS 69

Query: 73  Y--GFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVELD 130
              G  PG GY  G   G                   P   I  VT+N+SLL PL +E+D
Sbjct: 70  RCGGTLPGFGYRLGATCG-------------------PSACITPVTINESLLVPLALEID 110

Query: 131 PEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPI 190
           P +Q+V+  E+EQIK LN++FASFI+KVRFLEQ+N++LETKW  +QQ     C+ N+EPI
Sbjct: 111 PTVQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRC--CQTNIEPI 168

Query: 191 LEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKD 250
            EGYIS LR+QL+ +SGDRVRL+SEL S++  +E YKK+YE E++ R   ENEFV LKKD
Sbjct: 169 FEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKD 228

Query: 251 ADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSI 310
            D A+ +K +L+   ++L +EI FLK LY+ EI  +Q+  SETSVI+ MDN+R+LD+D I
Sbjct: 229 VDTAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGI 288

Query: 311 IAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRC 370
           IAE++  Y++IA +SKAEAEA YQ + +EL++ A  H D+L++ ++E++E+N+LIQR++ 
Sbjct: 289 IAEIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQ 348

Query: 371 EIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMS 430
           E  NVK QR  LE AIA+AEQ+G+ AL DA+ KL  LE AL +AK+++A +L+EYQE+M+
Sbjct: 349 ETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMN 408

Query: 431 LKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLGASAVAG 490
            KL LD+EIATYR+LLEGEE R+  E    V+ISV SS     + P      + ++ V  
Sbjct: 409 SKLGLDIEIATYRRLLEGEEHRLC-EGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLR 467

Query: 491 SSG 493
           S+G
Sbjct: 468 SNG 470


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  403 bits (1035), Expect = e-112
 Identities = 233/487 (47%), Positives = 318/487 (65%), Gaps = 36/487 (7%)

Query: 15  NFSVHSAVVPR---KAVGSLASYCAAGRGAG-AGFGSRSLYSLGGNRRISFNVAGGGVRA 70
           NFS  SAV P+   +   S A Y       G  GFGSRSL +LG        +A GG RA
Sbjct: 17  NFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLGS---CGPRIAVGGFRA 73

Query: 71  GGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVELD 130
           G  G     GY   R+ G  G         P C++         V+VN+SLL PLN+E+D
Sbjct: 74  GSCG--RSFGY---RSGGVCGP-------SPPCITT--------VSVNESLLTPLNLEID 113

Query: 131 PEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPI 190
           P  Q V+ +E+EQIK LN +FA+FIDKVRFLEQQN++LETKW+  Q  +   C+ NLEP+
Sbjct: 114 PNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ--NQRCCESNLEPL 171

Query: 191 LEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKD 250
             GYI  LR++ E +  D  RL SEL  +++++E YKK+YE E+  R TAENEFVVLKKD
Sbjct: 172 FSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKD 231

Query: 251 ADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSI 310
            D AY  K +L+A V++L +E  FL+ LY+ EI  +Q H S+TSVI+ MDN+RDL++D I
Sbjct: 232 VDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCI 291

Query: 311 IAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRC 370
           IAE++  Y+++A +S+AEAE+ Y++K +E++    RHG+ L+ T+ E+ ELNR+IQR+  
Sbjct: 292 IAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTA 351

Query: 371 EIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMS 430
           EI N K QRA LE A+A+AEQ+G+ AL DA+ KL ELEGAL +AK+++A +L+EYQE+M+
Sbjct: 352 EIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMN 411

Query: 431 LKLALDMEIATYRKLLEGEECRMSGENPSSVSISV------ISSSSYSYHHPSSAGVDLG 484
            KL LD+EIATYR+LLEGEE R+  E   SV++ V      +S    SY       +  G
Sbjct: 412 SKLGLDIEIATYRRLLEGEEHRLC-EGVGSVNVCVSSSRGGVSCGGLSYSTTPGRQITSG 470

Query: 485 ASAVAGS 491
            SA+ GS
Sbjct: 471 PSAIGGS 477


>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  381 bits (979), Expect = e-106
 Identities = 222/488 (45%), Positives = 311/488 (63%), Gaps = 50/488 (10%)

Query: 14  GNFSVHSAVVPRKAVGSLASYCAAG----RGAGAGFGSRSLYSLGGNRRISFNVAGGGVR 69
           GNFS  SA  PR +   + +    G    RG   GFGS S+               GG R
Sbjct: 15  GNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVC--------------GGFR 60

Query: 70  AGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVEL 129
           AG  G     GY   R+ G  G         P C++         V+VN+SLL PLN+E+
Sbjct: 61  AGSCG--RSFGY---RSGGVCGP-------SPPCITT--------VSVNESLLTPLNLEI 100

Query: 130 DPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEP 189
           DP  Q V+ +E+EQIK LN +FA+FIDKVRFLEQQN++LETK +  Q  +   C+ NLEP
Sbjct: 101 DPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEP 158

Query: 190 ILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKK 249
           +  GYI  LR++ E +  D  RL SEL  +++++E YKK+YE E+  R TAENEFV LKK
Sbjct: 159 LFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKK 218

Query: 250 DADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDS 309
           D D AY  K +L+A V++L +EI FL+ LY+ EI  +Q+H S+TSV++ +DN+RDL++D 
Sbjct: 219 DVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDC 278

Query: 310 IIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIR 369
           I+AE++  Y++IA +S+AEAE+ Y++K +E++    RHG+ L+ T+ E+ ELNR+IQR+ 
Sbjct: 279 IVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLT 338

Query: 370 CEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELM 429
            E+ N K Q + LE A+A +EQ+G+ AL DA+ KL ELEGAL +AK+++A ++REYQE+M
Sbjct: 339 AEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVM 398

Query: 430 SLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLGASAVA 489
           + KL LD+EIATYR+LLEGEE R+  E   +V++ V S         S  GV  G   V+
Sbjct: 399 NSKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSS---------SRGGVVCGDLCVS 448

Query: 490 GSSGSTQS 497
           GS   T S
Sbjct: 449 GSRPVTGS 456


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  379 bits (973), Expect = e-105
 Identities = 203/397 (51%), Positives = 284/397 (71%), Gaps = 11/397 (2%)

Query: 74  GFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGG--IHQVTVNKSLLAPLNVELDP 131
           GF   S  GG RA G  G  FG  + G     VC P    I  V+VN+SLL PLN+E+DP
Sbjct: 44  GFGSHSVCGGFRA-GSCGRSFGYRSGG-----VCGPSPPCITTVSVNESLLTPLNLEIDP 97

Query: 132 EIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPIL 191
             Q V+ +E+EQIK LN +FA+FIDKVRFLEQQN++LETK +  Q  +   C+ NLEP+ 
Sbjct: 98  NAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLF 155

Query: 192 EGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDA 251
           EGYI  LR++ E +  D  RL SEL  +++++E YKK+YE E++ R TAENEFV LKKD 
Sbjct: 156 EGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDV 215

Query: 252 DAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSII 311
           D AY  K +L+A V++L +EI FL+ LY+ EI  +Q+H S+TSV++ +DN+RDL++D II
Sbjct: 216 DCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCII 275

Query: 312 AEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCE 371
           AE++  Y++I  +S+AEAE+ Y++K +E++    RHG+ L+ T+ E+ ELNR+IQR+  E
Sbjct: 276 AEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE 335

Query: 372 IGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSL 431
           + N K Q + LE A+A +EQ+G+ AL DA+ KL ELEGAL +AK+++A ++REYQE+M+ 
Sbjct: 336 VENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNS 395

Query: 432 KLALDMEIATYRKLLEGEECRMSGENPSSVSISVISS 468
           KL LD+EIATYR+LLEGEE R+  E   SV++ V SS
Sbjct: 396 KLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  379 bits (973), Expect = e-105
 Identities = 203/397 (51%), Positives = 284/397 (71%), Gaps = 11/397 (2%)

Query: 74  GFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGG--IHQVTVNKSLLAPLNVELDP 131
           GF   S  GG RA G  G  FG  + G     VC P    I  V+VN+SLL PLN+E+DP
Sbjct: 44  GFGSHSVCGGFRA-GSCGRSFGYRSGG-----VCGPSPPCITTVSVNESLLTPLNLEIDP 97

Query: 132 EIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPIL 191
             Q V+ +E+EQIK LN +FA+FIDKVRFLEQQN++LETK +  Q  +   C+ NLEP+ 
Sbjct: 98  NAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLF 155

Query: 192 EGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDA 251
           EGYI  LR++ E +  D  RL SEL  +++++E YKK+YE E++ R TAENEFV LKKD 
Sbjct: 156 EGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDV 215

Query: 252 DAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSII 311
           D AY  K +L+A V++L +EI FL+ LY+ EI  +Q+H S+TSV++ +DN+RDL++D II
Sbjct: 216 DCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCII 275

Query: 312 AEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCE 371
           AE++  Y++I  +S+AEAE+ Y++K +E++    RHG+ L+ T+ E+ ELNR+IQR+  E
Sbjct: 276 AEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE 335

Query: 372 IGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSL 431
           + N K Q + LE A+A +EQ+G+ AL DA+ KL ELEGAL +AK+++A ++REYQE+M+ 
Sbjct: 336 VENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNS 395

Query: 432 KLALDMEIATYRKLLEGEECRMSGENPSSVSISVISS 468
           KL LD+EIATYR+LLEGEE R+  E   SV++ V SS
Sbjct: 396 KLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  379 bits (973), Expect = e-105
 Identities = 203/397 (51%), Positives = 284/397 (71%), Gaps = 11/397 (2%)

Query: 74  GFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGG--IHQVTVNKSLLAPLNVELDP 131
           GF   S  GG RA G  G  FG  + G     VC P    I  V+VN+SLL PLN+E+DP
Sbjct: 44  GFGSHSVCGGFRA-GSCGRSFGYRSGG-----VCGPSPPCITTVSVNESLLTPLNLEIDP 97

Query: 132 EIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPIL 191
             Q V+ +E+EQIK LN +FA+FIDKVRFLEQQN++LETK +  Q  +   C+ NLEP+ 
Sbjct: 98  NAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLF 155

Query: 192 EGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDA 251
           EGYI  LR++ E +  D  RL SEL  +++++E YKK+YE E++ R TAENEFV LKKD 
Sbjct: 156 EGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDV 215

Query: 252 DAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSII 311
           D AY  K +L+A V++L +EI FL+ LY+ EI  +Q+H S+TSV++ +DN+RDL++D II
Sbjct: 216 DCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCII 275

Query: 312 AEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCE 371
           AE++  Y++I  +S+AEAE+ Y++K +E++    RHG+ L+ T+ E+ ELNR+IQR+  E
Sbjct: 276 AEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE 335

Query: 372 IGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSL 431
           + N K Q + LE A+A +EQ+G+ AL DA+ KL ELEGAL +AK+++A ++REYQE+M+ 
Sbjct: 336 VENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNS 395

Query: 432 KLALDMEIATYRKLLEGEECRMSGENPSSVSISVISS 468
           KL LD+EIATYR+LLEGEE R+  E   SV++ V SS
Sbjct: 396 KLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  379 bits (973), Expect = e-105
 Identities = 203/397 (51%), Positives = 284/397 (71%), Gaps = 11/397 (2%)

Query: 74  GFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGG--IHQVTVNKSLLAPLNVELDP 131
           GF   S  GG RA G  G  FG  + G     VC P    I  V+VN+SLL PLN+E+DP
Sbjct: 44  GFGSHSVCGGFRA-GSCGRSFGYRSGG-----VCGPSPPCITTVSVNESLLTPLNLEIDP 97

Query: 132 EIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPIL 191
             Q V+ +E+EQIK LN +FA+FIDKVRFLEQQN++LETK +  Q  +   C+ NLEP+ 
Sbjct: 98  NAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLF 155

Query: 192 EGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDA 251
           EGYI  LR++ E +  D  RL SEL  +++++E YKK+YE E++ R TAENEFV LKKD 
Sbjct: 156 EGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDV 215

Query: 252 DAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSII 311
           D AY  K +L+A V++L +EI FL+ LY+ EI  +Q+H S+TSV++ +DN+RDL++D II
Sbjct: 216 DCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCII 275

Query: 312 AEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCE 371
           AE++  Y++I  +S+AEAE+ Y++K +E++    RHG+ L+ T+ E+ ELNR+IQR+  E
Sbjct: 276 AEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE 335

Query: 372 IGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSL 431
           + N K Q + LE A+A +EQ+G+ AL DA+ KL ELEGAL +AK+++A ++REYQE+M+ 
Sbjct: 336 VENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNS 395

Query: 432 KLALDMEIATYRKLLEGEECRMSGENPSSVSISVISS 468
           KL LD+EIATYR+LLEGEE R+  E   SV++ V SS
Sbjct: 396 KLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  379 bits (973), Expect = e-105
 Identities = 221/468 (47%), Positives = 307/468 (65%), Gaps = 32/468 (6%)

Query: 42  GAGFGSR--SLYSLGGNRRISFNVAGGGVRA--------GGYGFRPGSGYGGGRASGFAG 91
           G+GFG R  S  S  G R     +     R         GG+G    S  GG RA G  G
Sbjct: 4   GSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSH--SVCGGFRA-GSCG 60

Query: 92  SMFGSVALGPACLSVCPPGG--IHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLND 149
             FG  + G     VC P    I  V+VN+SLL PLN+E+DP  Q V+ +E+EQIK LN 
Sbjct: 61  RSFGYRSGG-----VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115

Query: 150 KFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLSGDR 209
           +FA+FIDKVRFLEQQN++LETK +  Q  +   C+ NLEP+ EGYI  LR++ E +  D 
Sbjct: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREAECVEADS 173

Query: 210 VRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLD 269
            RL SEL  +++++E YKK+YE E++ R TAENEFV LKKD D AY  K +L+A V++L 
Sbjct: 174 GRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALI 233

Query: 270 KEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEA 329
           +EI FL+ LY+ EI  +Q+H S+TSV++ +DN+RDL++D IIAE++  Y++I  +S+AEA
Sbjct: 234 QEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEA 293

Query: 330 EALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADA 389
           E+ Y++K +E++    RHG+ L+ T+ E+ ELNR+IQR+  E+ N K Q + LE A+A +
Sbjct: 294 ESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQS 353

Query: 390 EQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGE 449
           EQ+G+ AL DA+ KL ELEGAL +AK+++A ++REYQE+M+ KL LD+EIATYR+LLEGE
Sbjct: 354 EQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGE 413

Query: 450 ECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLGASAVAGSSGSTQS 497
           E R+  E   +V++ V S         S  GV  G   V+GS   T S
Sbjct: 414 EQRLC-EGIGAVNVCVSS---------SRGGVVCGDLCVSGSRPVTGS 451


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,167,633
Number of Sequences: 37866
Number of extensions: 835711
Number of successful extensions: 7052
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 212
Number of HSP's successfully gapped in prelim test: 540
Number of HSP's that attempted gapping in prelim test: 4340
Number of HSP's gapped (non-prelim): 2037
length of query: 529
length of database: 18,247,518
effective HSP length: 107
effective length of query: 422
effective length of database: 14,195,856
effective search space: 5990651232
effective search space used: 5990651232
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.