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Search of human proteins with 148368987
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148368987 kleisin beta isoform 1 [Homo sapiens]
(299 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148368987 kleisin beta isoform 1 [Homo sapiens] 602 e-172
gi|148368978 kleisin beta isoform 2 [Homo sapiens] 575 e-164
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 47 3e-05
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 47 3e-05
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 47 3e-05
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 47 3e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 42 9e-04
gi|33286446 opioid growth factor receptor [Homo sapiens] 40 0.002
gi|22902136 osterix [Homo sapiens] 40 0.002
gi|194578898 hypothetical protein LOC100170841 [Homo sapiens] 40 0.002
gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3 pre... 40 0.002
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 39 0.004
gi|45827729 scribble isoform b [Homo sapiens] 39 0.006
gi|45827731 scribble isoform a [Homo sapiens] 39 0.006
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 37 0.016
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 37 0.016
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 37 0.016
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 37 0.016
gi|7662302 TBK1 binding protein 1 [Homo sapiens] 37 0.016
gi|24307909 ral guanine nucleotide dissociation stimulator isofo... 37 0.021
gi|108796058 ral guanine nucleotide dissociation stimulator isof... 37 0.021
gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens] 37 0.021
gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens] 37 0.021
gi|28559071 DNA cytosine methyltransferase 3 alpha isoform c [Ho... 36 0.036
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 36 0.036
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 36 0.036
gi|144922631 tigger transposable element derived 5 [Homo sapiens] 36 0.047
gi|110349719 titin isoform N2-A [Homo sapiens] 35 0.061
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 35 0.061
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 35 0.061
>gi|148368987 kleisin beta isoform 1 [Homo sapiens]
Length = 299
Score = 602 bits (1553), Expect = e-172
Identities = 299/299 (100%), Positives = 299/299 (100%)
Query: 1 MEDVEARFAHLLQPIRDLTKNWEVDVAAQLGEYLEELDQICISFDEGKTTMNFIEAALLI 60
MEDVEARFAHLLQPIRDLTKNWEVDVAAQLGEYLEELDQICISFDEGKTTMNFIEAALLI
Sbjct: 1 MEDVEARFAHLLQPIRDLTKNWEVDVAAQLGEYLEELDQICISFDEGKTTMNFIEAALLI 60
Query: 61 QGSACVYSKKVEYLYSLVYQALDFISGKRRAKQLSSVQEDRANGVASSGVPQEAENEFLS 120
QGSACVYSKKVEYLYSLVYQALDFISGKRRAKQLSSVQEDRANGVASSGVPQEAENEFLS
Sbjct: 61 QGSACVYSKKVEYLYSLVYQALDFISGKRRAKQLSSVQEDRANGVASSGVPQEAENEFLS 120
Query: 121 LDDFPDSRTNVDLKNDQTPSEVLIIPLLPMALVAPDEMEKNNNPLYSRQGEVLASRKDFR 180
LDDFPDSRTNVDLKNDQTPSEVLIIPLLPMALVAPDEMEKNNNPLYSRQGEVLASRKDFR
Sbjct: 121 LDDFPDSRTNVDLKNDQTPSEVLIIPLLPMALVAPDEMEKNNNPLYSRQGEVLASRKDFR 180
Query: 181 MNTCVPHPRGAFMLEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFS 240
MNTCVPHPRGAFMLEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFS
Sbjct: 181 MNTCVPHPRGAFMLEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFS 240
Query: 241 QEPGPSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEPEL 299
QEPGPSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEPEL
Sbjct: 241 QEPGPSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEPEL 299
>gi|148368978 kleisin beta isoform 2 [Homo sapiens]
Length = 605
Score = 575 bits (1483), Expect = e-164
Identities = 287/287 (100%), Positives = 287/287 (100%)
Query: 1 MEDVEARFAHLLQPIRDLTKNWEVDVAAQLGEYLEELDQICISFDEGKTTMNFIEAALLI 60
MEDVEARFAHLLQPIRDLTKNWEVDVAAQLGEYLEELDQICISFDEGKTTMNFIEAALLI
Sbjct: 1 MEDVEARFAHLLQPIRDLTKNWEVDVAAQLGEYLEELDQICISFDEGKTTMNFIEAALLI 60
Query: 61 QGSACVYSKKVEYLYSLVYQALDFISGKRRAKQLSSVQEDRANGVASSGVPQEAENEFLS 120
QGSACVYSKKVEYLYSLVYQALDFISGKRRAKQLSSVQEDRANGVASSGVPQEAENEFLS
Sbjct: 61 QGSACVYSKKVEYLYSLVYQALDFISGKRRAKQLSSVQEDRANGVASSGVPQEAENEFLS 120
Query: 121 LDDFPDSRTNVDLKNDQTPSEVLIIPLLPMALVAPDEMEKNNNPLYSRQGEVLASRKDFR 180
LDDFPDSRTNVDLKNDQTPSEVLIIPLLPMALVAPDEMEKNNNPLYSRQGEVLASRKDFR
Sbjct: 121 LDDFPDSRTNVDLKNDQTPSEVLIIPLLPMALVAPDEMEKNNNPLYSRQGEVLASRKDFR 180
Query: 181 MNTCVPHPRGAFMLEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFS 240
MNTCVPHPRGAFMLEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFS
Sbjct: 181 MNTCVPHPRGAFMLEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFS 240
Query: 241 QEPGPSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQ 287
QEPGPSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQ
Sbjct: 241 QEPGPSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQ 287
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 46.6 bits (109), Expect = 3e-05
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
Query: 194 LEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPMPL 253
L P+ + P +G+ P + T + ++ PVP+L PS P
Sbjct: 1025 LLPQHLQPSSSSGLGTSPSSSPRTSPCQSP----TISEGPVPSLPIRPSRAPSRTPGPPS 1080
Query: 254 GGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEPE 298
DA+ A LP+ P LEPK P+ V P RPA P+
Sbjct: 1081 AQSSPIDAQPATPLPQKD-PAQPLEPKRPPPPRPVAPPTRPAPPQ 1124
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 46.6 bits (109), Expect = 3e-05
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
Query: 194 LEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPMPL 253
L P+ + P +G+ P + T + ++ PVP+L PS P
Sbjct: 1064 LLPQHLQPSSSSGLGTSPSSSPRTSPCQSP----TISEGPVPSLPIRPSRAPSRTPGPPS 1119
Query: 254 GGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEPE 298
DA+ A LP+ P LEPK P+ V P RPA P+
Sbjct: 1120 AQSSPIDAQPATPLPQKD-PAQPLEPKRPPPPRPVAPPTRPAPPQ 1163
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 46.6 bits (109), Expect = 3e-05
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
Query: 194 LEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPMPL 253
L P+ + P +G+ P + T + ++ PVP+L PS P
Sbjct: 1064 LLPQHLQPSSSSGLGTSPSSSPRTSPCQSP----TISEGPVPSLPIRPSRAPSRTPGPPS 1119
Query: 254 GGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEPE 298
DA+ A LP+ P LEPK P+ V P RPA P+
Sbjct: 1120 AQSSPIDAQPATPLPQKD-PAQPLEPKRPPPPRPVAPPTRPAPPQ 1163
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 46.6 bits (109), Expect = 3e-05
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 5/105 (4%)
Query: 194 LEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPMPL 253
L P+ + P +G+ P + T + ++ PVP+L PS P
Sbjct: 1020 LLPQHLQPSSSSGLGTSPSSSPRTSPCQSP----TISEGPVPSLPIRPSRAPSRTPGPPS 1075
Query: 254 GGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEPE 298
DA+ A LP+ P LEPK P+ V P RPA P+
Sbjct: 1076 AQSSPIDAQPATPLPQKD-PAQPLEPKRPPPPRPVAPPTRPAPPQ 1119
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 41.6 bits (96), Expect = 9e-04
Identities = 37/125 (29%), Positives = 51/125 (40%), Gaps = 11/125 (8%)
Query: 186 PHPRGAFMLEPEGMSPMEP----AGVSPMPGTQKDTGRTEEQPM----EVSVCRSPVPAL 237
P P + M P SPM P + +SP+P + + EE P+ E S P A
Sbjct: 628 PPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS 687
Query: 238 GFSQEPGPSPEGPMPLGGGEDEDAEEA-VELPEASAPKAALEPKESRSPQQVGP--TWRP 294
S P SP P P E++ + LP +P L + P+ GP + RP
Sbjct: 688 RLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRP 747
Query: 295 AEPEL 299
EP L
Sbjct: 748 EEPHL 752
Score = 31.2 bits (69), Expect = 1.2
Identities = 29/102 (28%), Positives = 37/102 (36%), Gaps = 8/102 (7%)
Query: 193 MLEPEGMSPMEP----AGVSPMPGTQKDTGRTEEQPM----EVSVCRSPVPALGFSQEPG 244
+L P SP+ P + SP P + + EE P E P+ S P
Sbjct: 440 LLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPE 499
Query: 245 PSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQ 286
SP P P E + PE S P ALE S P+
Sbjct: 500 ESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPE 541
Score = 28.1 bits (61), Expect = 9.8
Identities = 36/154 (23%), Positives = 60/154 (38%), Gaps = 15/154 (9%)
Query: 152 LVAPDEMEKNNNPLYSRQGEVLASRKDFRMNTCV----PHPRGAFMLEP-EGMSPMEPAG 206
++A + ++ +P +Q + L ++ + + V P+ P +G+ +P
Sbjct: 4204 VLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQ- 4262
Query: 207 VSPMPGTQKDTGRTEEQ---PMEVSVCRSPVPALGFSQEPGPSPEGPMPLGGGEDEDAEE 263
+ PG Q TG +E P R P P S P P P P E
Sbjct: 4263 LGGFPGPQ--TGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRP 4320
Query: 264 AVELPEASAP---KAALEPKESRSPQQVGPTWRP 294
+ +LP S+ +A L P +P+ GPT P
Sbjct: 4321 S-QLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEP 4353
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 40.4 bits (93), Expect = 0.002
Identities = 38/111 (34%), Positives = 41/111 (36%), Gaps = 23/111 (20%)
Query: 195 EPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPE---GPM 251
E G SP PAG P E P E P PA EP SP GP
Sbjct: 520 ETPGPSPAGPAGDEPA-----------ESPSETP---GPRPAGPAGDEPAESPSETPGPR 565
Query: 252 PLGGGEDEDAEEAVELPEAS-----APKAALEPKESRSPQQVGPTW-RPAE 296
P G DE AE E P S + A P E+ P+ GP PAE
Sbjct: 566 PAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAE 616
Score = 38.9 bits (89), Expect = 0.006
Identities = 34/90 (37%), Positives = 36/90 (40%), Gaps = 12/90 (13%)
Query: 186 PHPRGAFMLEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEV-SVCRSPVPALGFSQEPG 244
P P G EP SP E G SP G T ++P E S P PA EP
Sbjct: 564 PRPAGPAGDEP-AESPSETPGPSP-------AGPTRDEPAESPSETPGPRPAGPAGDEPA 615
Query: 245 PSPE---GPMPLGGGEDEDAEEAVELPEAS 271
SP GP P G DE AE E P S
Sbjct: 616 ESPSETPGPRPAGPAGDEPAESPSETPGPS 645
Score = 35.8 bits (81), Expect = 0.047
Identities = 28/86 (32%), Positives = 32/86 (37%), Gaps = 9/86 (10%)
Query: 195 EPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPMPLG 254
E G P PAG P + G P SP S+ PGPSP GP
Sbjct: 600 ETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESP------SETPGPSPAGPT--- 650
Query: 255 GGEDEDAEEAVELPEASAPKAALEPK 280
E A EA EL +A +A K
Sbjct: 651 RDEPAKAGEAAELQDAEVESSAKSGK 676
Score = 33.5 bits (75), Expect = 0.23
Identities = 35/114 (30%), Positives = 42/114 (36%), Gaps = 26/114 (22%)
Query: 208 SPMPGTQKDTGRTEEQPMEVSVCRSPVPALGF----SQEPGPSP---------------E 248
SP P G +E E + R+ P G S+ PGPSP
Sbjct: 484 SPAPSGHPKAGHSENGVEEDTEGRTG-PKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542
Query: 249 GPMPLGGGEDEDAEEAVELP-----EASAPKAALEPKESRSPQQVGPTW-RPAE 296
GP P G DE AE E P + + A P E+ P GPT PAE
Sbjct: 543 GPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAE 596
Score = 33.1 bits (74), Expect = 0.31
Identities = 34/113 (30%), Positives = 46/113 (40%), Gaps = 18/113 (15%)
Query: 185 VPHP-RGAFMLEPEGMSPMEP------AGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPAL 237
+PHP G+ +E EG SP +P G + P K GR +E P SV
Sbjct: 300 LPHPLEGSRKVEEEG-SPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSV-------- 350
Query: 238 GFSQEPGPSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGP 290
Q+ GP GG ED E + E+ K L +E + P + GP
Sbjct: 351 -EPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRRE-QPPTEPGP 401
>gi|22902136 osterix [Homo sapiens]
Length = 431
Score = 40.0 bits (92), Expect = 0.002
Identities = 20/45 (44%), Positives = 22/45 (48%)
Query: 243 PGPSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQ 287
PGP P GP LG G EEA + P SA A E SP+Q
Sbjct: 381 PGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPGGSPEQ 425
>gi|194578898 hypothetical protein LOC100170841 [Homo sapiens]
Length = 379
Score = 40.0 bits (92), Expect = 0.002
Identities = 30/105 (28%), Positives = 38/105 (36%), Gaps = 11/105 (10%)
Query: 186 PHPRGAFMLEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGP 245
PHPR E + A P PG + G P E S R P P G S EP
Sbjct: 144 PHPR-------ESTTSFASAPPRPAPGLEPQRGPAASPPQEPS-SRPPSPPAGLSTEPAG 195
Query: 246 SPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGP 290
P P G+ + + P +AP+A + SP P
Sbjct: 196 PGTAPRPFLPGQPAEVDGN---PPPAAPEAPAASPSTASPAPAAP 237
Score = 28.5 bits (62), Expect = 7.5
Identities = 18/63 (28%), Positives = 22/63 (34%)
Query: 195 EPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPMPLG 254
EP P PAG+S P R V +P PA + PS P P
Sbjct: 177 EPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAA 236
Query: 255 GGE 257
G+
Sbjct: 237 PGD 239
>gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3
preproprotein [Homo sapiens]
Length = 178
Score = 40.0 bits (92), Expect = 0.002
Identities = 39/174 (22%), Positives = 66/174 (37%), Gaps = 23/174 (13%)
Query: 143 LIIPLLPMALVAPDEMEKNNNPLYSRQGEVLASRKDFRMNTCVPHPRGAFMLEPEGMSPM 202
+++ LL +AL+A + N + + L + N P P+G + P
Sbjct: 1 MLLILLSVALLALSSAQNLNEDVSQEESPSLIAG-----NPQGPSPQGGNKPQGPPPPPG 55
Query: 203 EPAGVSPMPGTQKD----TGRTEEQPMEVSVCRSPVPALGFSQEPGPS---PEGPMPLGG 255
+P G P G + G+ + P + RSP G Q P P P+GP GG
Sbjct: 56 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGG 115
Query: 256 GEDEDA-----------EEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEPE 298
+ + A ++ P+ P A P++ ++P P P P+
Sbjct: 116 SKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQ 169
Score = 33.1 bits (74), Expect = 0.31
Identities = 31/106 (29%), Positives = 42/106 (39%), Gaps = 12/106 (11%)
Query: 186 PHPRGAFMLEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPV-PALGFSQEPG 244
P P+G P P +P G P G K G + + RSP G Q+ G
Sbjct: 80 PPPQGDKSRSPRS-PPGKPQGPPPQGG--KPQGPPAQGGSKSQSARSPPGKPQGPPQQEG 136
Query: 245 PSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEP----KESRSPQ 286
+P+GP P GG + + P A P+ P + SR PQ
Sbjct: 137 NNPQGPPPPAGGNPQQP----QAPPAGQPQGPPRPPQGGRPSRPPQ 178
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 39.3 bits (90), Expect = 0.004
Identities = 33/118 (27%), Positives = 43/118 (36%), Gaps = 19/118 (16%)
Query: 186 PHPRGAFMLEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGP 245
P P+G + P +P G P G Q ++ P P P G +Q GP
Sbjct: 123 PPPQGGNQSQGPPPRPGKPEGPPPQGGNQ-----SQGPPPRPGKPEGPPPQ-GGNQSQGP 176
Query: 246 -----SPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEPE 298
PEGP P GG + + PE P+ Q GP RP +PE
Sbjct: 177 PPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQG--------GNQSQGPPPRPGKPE 226
Score = 38.1 bits (87), Expect = 0.009
Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 29/121 (23%)
Query: 188 PRGAFMLEPEGMSPMEPAGVSPMPGTQKD-----TGRTEEQPMEVSVCRSPVPALGFSQE 242
P+G + P +P G P G Q G+ E QP + G +Q
Sbjct: 62 PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQ-----------GGNQS 110
Query: 243 PGP-----SPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEP 297
GP PEGP P GG + + PE P+ Q GP RP +P
Sbjct: 111 QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQG--------GNQSQGPPPRPGKP 162
Query: 298 E 298
E
Sbjct: 163 E 163
Score = 38.1 bits (87), Expect = 0.009
Identities = 34/131 (25%), Positives = 45/131 (34%), Gaps = 24/131 (18%)
Query: 186 PHPRGAFMLEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGP 245
P P+G + P +P G P G Q ++ P P P G +Q GP
Sbjct: 81 PPPQGGNQSQGPPPRPGKPEGQPPQGGNQ-----SQGPPPRPGKPEGPPPQ-GGNQSQGP 134
Query: 246 -----SPEGPMPLGGGEDEDAEEAVELPEASAPKAALE-------------PKESRSPQQ 287
PEGP P GG + + PE P+ + P Q
Sbjct: 135 PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQS 194
Query: 288 VGPTWRPAEPE 298
GP RP +PE
Sbjct: 195 QGPPPRPGKPE 205
Score = 37.0 bits (84), Expect = 0.021
Identities = 33/112 (29%), Positives = 40/112 (35%), Gaps = 33/112 (29%)
Query: 195 EPEGMSPM---EPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGP-----S 246
+PEG P +P P PG K GR P G +Q GP
Sbjct: 35 KPEGRRPQGGNQPQRTPPPPG--KPEGR---------------PPQGGNQSQGPPPRPGK 77
Query: 247 PEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEPE 298
PEGP P GG + + PE P+ Q GP RP +PE
Sbjct: 78 PEGPPPQGGNQSQGPPPRPGKPEGQPPQG--------GNQSQGPPPRPGKPE 121
Score = 35.8 bits (81), Expect = 0.047
Identities = 33/132 (25%), Positives = 45/132 (34%), Gaps = 26/132 (19%)
Query: 186 PHPRGAFMLEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGP 245
P P+G + P +P G P G Q ++ P P P G +Q GP
Sbjct: 144 PPPQGGNQSQGPPPRPGKPEGPPPQGGNQ-----SQGPPPHPGKPEGPPPQ-GGNQSQGP 197
Query: 246 -----SPEGPMPLGGGEDEDAEEAVELPEASAPKAALE---------------PKESRSP 285
PEGP P GG + + PE + + P+E P
Sbjct: 198 PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKP 257
Query: 286 QQVGPTWRPAEP 297
Q+ P RP P
Sbjct: 258 QRPPPPGRPQGP 269
Score = 31.6 bits (70), Expect = 0.89
Identities = 33/130 (25%), Positives = 45/130 (34%), Gaps = 30/130 (23%)
Query: 186 PHPRGAFMLEPEGMSPMEPAGVSPMPGTQKD-----TGRTEEQPMEV-SVCRSPVPALGF 239
P P+G + P +P G P G Q G+ E P + + + P P G
Sbjct: 186 PPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGK 245
Query: 240 SQEPGPS-------------PEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQ 286
Q P P P+GP P GG P+ P A +P+ P
Sbjct: 246 PQGPPPQEGNKPQRPPPPGRPQGPPPPGGN-----------PQQPLPPPAGKPQGPPPPP 294
Query: 287 QVGPTWRPAE 296
Q G RP +
Sbjct: 295 QGGRPHRPPQ 304
>gi|45827729 scribble isoform b [Homo sapiens]
Length = 1630
Score = 38.9 bits (89), Expect = 0.006
Identities = 43/183 (23%), Positives = 70/183 (38%), Gaps = 26/183 (14%)
Query: 119 LSLDDFPDSRTNVDLKNDQTPSEVLIIPLLPMALVAPDEMEKNNNPLYSRQGEVLASRKD 178
LSL+D + + +D PS V +I L P+ E A+ K
Sbjct: 422 LSLEDAGQQGSLSETWSDAPPSRVSVIQFLEA-------------PIGDEDAEEAAAEKR 468
Query: 179 FRMNTCVPHPRGAFMLEP--EGMS----PMEPAGVSPMPGTQK-----DTGRTEEQPMEV 227
PHP +++ EG P +P SP+P ++ ++G +E+
Sbjct: 469 GLQRRATPHPSELKVMKRSIEGRRSEACPCQPDSGSPLPAEEEKRLSAESGLSEDSRPSA 528
Query: 228 SVCRSPVPALGFSQEPGPSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQ 287
S P ++ G S + GG +EDAEE + P + AL P + R ++
Sbjct: 529 STVSEAEPEGPSAEAQGGSQQEATTAGG--EEDAEEDYQEPTVHFAEDALLPGDDREIEE 586
Query: 288 VGP 290
P
Sbjct: 587 GQP 589
Score = 34.3 bits (77), Expect = 0.14
Identities = 32/101 (31%), Positives = 39/101 (38%), Gaps = 16/101 (15%)
Query: 205 AGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPMPLGGGEDEDAEEA 264
AG +T EEQ E SP P SP P PLGGG +A
Sbjct: 1410 AGAEARLALDGETLGEEEQEDEQPPWASPSPT------SRQSPASPPPLGGGAPVRTAKA 1463
Query: 265 ---------VELPEASAPKAALEPKESRSPQ-QVGPTWRPA 295
V+ PE AP+ AL P E R+ + + WR A
Sbjct: 1464 ERRHQERLRVQSPEPPAPERALSPAELRALEAEKRALWRAA 1504
>gi|45827731 scribble isoform a [Homo sapiens]
Length = 1655
Score = 38.9 bits (89), Expect = 0.006
Identities = 43/183 (23%), Positives = 70/183 (38%), Gaps = 26/183 (14%)
Query: 119 LSLDDFPDSRTNVDLKNDQTPSEVLIIPLLPMALVAPDEMEKNNNPLYSRQGEVLASRKD 178
LSL+D + + +D PS V +I L P+ E A+ K
Sbjct: 422 LSLEDAGQQGSLSETWSDAPPSRVSVIQFLEA-------------PIGDEDAEEAAAEKR 468
Query: 179 FRMNTCVPHPRGAFMLEP--EGMS----PMEPAGVSPMPGTQK-----DTGRTEEQPMEV 227
PHP +++ EG P +P SP+P ++ ++G +E+
Sbjct: 469 GLQRRATPHPSELKVMKRSIEGRRSEACPCQPDSGSPLPAEEEKRLSAESGLSEDSRPSA 528
Query: 228 SVCRSPVPALGFSQEPGPSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQ 287
S P ++ G S + GG +EDAEE + P + AL P + R ++
Sbjct: 529 STVSEAEPEGPSAEAQGGSQQEATTAGG--EEDAEEDYQEPTVHFAEDALLPGDDREIEE 586
Query: 288 VGP 290
P
Sbjct: 587 GQP 589
Score = 34.3 bits (77), Expect = 0.14
Identities = 32/101 (31%), Positives = 39/101 (38%), Gaps = 16/101 (15%)
Query: 205 AGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPMPLGGGEDEDAEEA 264
AG +T EEQ E SP P SP P PLGGG +A
Sbjct: 1410 AGAEARLALDGETLGEEEQEDEQPPWASPSPT------SRQSPASPPPLGGGAPVRTAKA 1463
Query: 265 ---------VELPEASAPKAALEPKESRSPQ-QVGPTWRPA 295
V+ PE AP+ AL P E R+ + + WR A
Sbjct: 1464 ERRHQERLRVQSPEPPAPERALSPAELRALEAEKRALWRAA 1504
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 37.4 bits (85), Expect = 0.016
Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 11/109 (10%)
Query: 195 EPEGMSPMEPAGVS---PMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGP-SPEGP 250
EP +P EPA + P P T K T ++P + + P P +EP P +P+ P
Sbjct: 269 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP-KKPAPTT--PKEPAPTTPKEP 325
Query: 251 MPLGGGEDEDA--EEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEP 297
P E E A P+ AP A +P + +P++ PT P EP
Sbjct: 326 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPT-TPKEP 372
Score = 31.6 bits (70), Expect = 0.89
Identities = 25/106 (23%), Positives = 40/106 (37%), Gaps = 5/106 (4%)
Query: 195 EPEGMSPMEPAGVSPM---PGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPM 251
EP +P EPA +P P T K+ T + + + P P P + P
Sbjct: 339 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 398
Query: 252 PLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEP 297
+ A P+ +P EP + +P++ PT P +P
Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT-TPKEPAPT-TPKKP 442
Score = 30.4 bits (67), Expect = 2.0
Identities = 31/113 (27%), Positives = 44/113 (38%), Gaps = 12/113 (10%)
Query: 195 EPEGMSPMEPAGVS--PMPGTQKDTGRTEEQ------PMEVSVCRSPVPALGFSQEPGP- 245
EP +P EPA + P P T K+ T + P E + PA ++EP P
Sbjct: 324 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 383
Query: 246 SPEGPMP-LGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEP 297
+P+ P P +E SAP EP + + + T P EP
Sbjct: 384 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT--PKEP 434
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 37.4 bits (85), Expect = 0.016
Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 11/109 (10%)
Query: 195 EPEGMSPMEPAGVS---PMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGP-SPEGP 250
EP +P EPA + P P T K T ++P + + P P +EP P +P+ P
Sbjct: 310 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP-KKPAPTT--PKEPAPTTPKEP 366
Query: 251 MPLGGGEDEDA--EEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEP 297
P E E A P+ AP A +P + +P++ PT P EP
Sbjct: 367 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPT-TPKEP 413
Score = 31.6 bits (70), Expect = 0.89
Identities = 25/106 (23%), Positives = 40/106 (37%), Gaps = 5/106 (4%)
Query: 195 EPEGMSPMEPAGVSPM---PGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPM 251
EP +P EPA +P P T K+ T + + + P P P + P
Sbjct: 380 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 439
Query: 252 PLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEP 297
+ A P+ +P EP + +P++ PT P +P
Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT-TPKEPAPT-TPKKP 483
Score = 30.4 bits (67), Expect = 2.0
Identities = 31/113 (27%), Positives = 44/113 (38%), Gaps = 12/113 (10%)
Query: 195 EPEGMSPMEPAGVS--PMPGTQKDTGRTEEQ------PMEVSVCRSPVPALGFSQEPGP- 245
EP +P EPA + P P T K+ T + P E + PA ++EP P
Sbjct: 365 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 424
Query: 246 SPEGPMP-LGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEP 297
+P+ P P +E SAP EP + + + T P EP
Sbjct: 425 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT--PKEP 475
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 37.4 bits (85), Expect = 0.016
Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 11/109 (10%)
Query: 195 EPEGMSPMEPAGVS---PMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGP-SPEGP 250
EP +P EPA + P P T K T ++P + + P P +EP P +P+ P
Sbjct: 362 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP-KKPAPTT--PKEPAPTTPKEP 418
Query: 251 MPLGGGEDEDA--EEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEP 297
P E E A P+ AP A +P + +P++ PT P EP
Sbjct: 419 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPT-TPKEP 465
Score = 31.6 bits (70), Expect = 0.89
Identities = 25/106 (23%), Positives = 40/106 (37%), Gaps = 5/106 (4%)
Query: 195 EPEGMSPMEPAGVSPM---PGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPM 251
EP +P EPA +P P T K+ T + + + P P P + P
Sbjct: 432 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 491
Query: 252 PLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEP 297
+ A P+ +P EP + +P++ PT P +P
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT-TPKEPAPT-TPKKP 535
Score = 30.4 bits (67), Expect = 2.0
Identities = 31/113 (27%), Positives = 44/113 (38%), Gaps = 12/113 (10%)
Query: 195 EPEGMSPMEPAGVS--PMPGTQKDTGRTEEQ------PMEVSVCRSPVPALGFSQEPGP- 245
EP +P EPA + P P T K+ T + P E + PA ++EP P
Sbjct: 417 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 476
Query: 246 SPEGPMP-LGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEP 297
+P+ P P +E SAP EP + + + T P EP
Sbjct: 477 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT--PKEP 527
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 37.4 bits (85), Expect = 0.016
Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 11/109 (10%)
Query: 195 EPEGMSPMEPAGVS---PMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGP-SPEGP 250
EP +P EPA + P P T K T ++P + + P P +EP P +P+ P
Sbjct: 403 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP-KKPAPTT--PKEPAPTTPKEP 459
Query: 251 MPLGGGEDEDA--EEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEP 297
P E E A P+ AP A +P + +P++ PT P EP
Sbjct: 460 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPT-TPKEP 506
Score = 31.6 bits (70), Expect = 0.89
Identities = 25/106 (23%), Positives = 40/106 (37%), Gaps = 5/106 (4%)
Query: 195 EPEGMSPMEPAGVSPM---PGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPM 251
EP +P EPA +P P T K+ T + + + P P P + P
Sbjct: 473 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 532
Query: 252 PLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEP 297
+ A P+ +P EP + +P++ PT P +P
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT-TPKEPAPT-TPKKP 576
Score = 30.4 bits (67), Expect = 2.0
Identities = 31/113 (27%), Positives = 44/113 (38%), Gaps = 12/113 (10%)
Query: 195 EPEGMSPMEPAGVS--PMPGTQKDTGRTEEQ------PMEVSVCRSPVPALGFSQEPGP- 245
EP +P EPA + P P T K+ T + P E + PA ++EP P
Sbjct: 458 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 517
Query: 246 SPEGPMP-LGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEP 297
+P+ P P +E SAP EP + + + T P EP
Sbjct: 518 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT--PKEP 568
>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
Length = 615
Score = 37.4 bits (85), Expect = 0.016
Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 6/98 (6%)
Query: 200 SPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPMPLGGGEDE 259
SP P+ SP+P + + + P RSPVP P P P P P GE
Sbjct: 385 SPASPSCPSPVPQRRSPVPPSCQSPSPQR--RSPVPP----SCPAPQPRPPPPPPPGERT 438
Query: 260 DAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEP 297
AE A P + KA + + S S G + A P
Sbjct: 439 LAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASP 476
>gi|24307909 ral guanine nucleotide dissociation stimulator isoform
1 [Homo sapiens]
Length = 914
Score = 37.0 bits (84), Expect = 0.021
Identities = 31/95 (32%), Positives = 39/95 (41%), Gaps = 20/95 (21%)
Query: 203 EPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPE-GPMPLGGGEDEDA 261
EP +SP+P + T E + ++ R+P P P P PE P P G E E A
Sbjct: 257 EPEALSPVPALKP----TPELELALTPARAPSPV----PAPAPEPEPAPTPAPGSELEVA 308
Query: 262 -----------EEAVELPEASAPKAALEPKESRSP 285
E AV L A AP LEP + P
Sbjct: 309 PAPAPELQQAPEPAVGLESAPAPALELEPAPEQDP 343
Score = 32.3 bits (72), Expect = 0.52
Identities = 21/87 (24%), Positives = 35/87 (40%), Gaps = 6/87 (6%)
Query: 199 MSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEP------GPSPEGPMP 252
++P P P + + T E+ V +P P L + EP P+P +
Sbjct: 277 LTPARAPSPVPAPAPEPEPAPTPAPGSELEVAPAPAPELQQAPEPAVGLESAPAPALELE 336
Query: 253 LGGGEDEDAEEAVELPEASAPKAALEP 279
+D + +EL A AP +L+P
Sbjct: 337 PAPEQDPAPSQTLELEPAPAPVPSLQP 363
>gi|108796058 ral guanine nucleotide dissociation stimulator isoform
2 [Homo sapiens]
Length = 859
Score = 37.0 bits (84), Expect = 0.021
Identities = 31/95 (32%), Positives = 39/95 (41%), Gaps = 20/95 (21%)
Query: 203 EPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPE-GPMPLGGGEDEDA 261
EP +SP+P + T E + ++ R+P P P P PE P P G E E A
Sbjct: 202 EPEALSPVPALKP----TPELELALTPARAPSPV----PAPAPEPEPAPTPAPGSELEVA 253
Query: 262 -----------EEAVELPEASAPKAALEPKESRSP 285
E AV L A AP LEP + P
Sbjct: 254 PAPAPELQQAPEPAVGLESAPAPALELEPAPEQDP 288
Score = 32.3 bits (72), Expect = 0.52
Identities = 21/87 (24%), Positives = 35/87 (40%), Gaps = 6/87 (6%)
Query: 199 MSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEP------GPSPEGPMP 252
++P P P + + T E+ V +P P L + EP P+P +
Sbjct: 222 LTPARAPSPVPAPAPEPEPAPTPAPGSELEVAPAPAPELQQAPEPAVGLESAPAPALELE 281
Query: 253 LGGGEDEDAEEAVELPEASAPKAALEP 279
+D + +EL A AP +L+P
Sbjct: 282 PAPEQDPAPSQTLELEPAPAPVPSLQP 308
>gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]
Length = 755
Score = 37.0 bits (84), Expect = 0.021
Identities = 35/122 (28%), Positives = 48/122 (39%), Gaps = 17/122 (13%)
Query: 186 PHPRGAFMLEPEGMSPM--EPAGVSPMPGTQKDT----GRTEEQPMEVSVCRSPVPALGF 239
P GA EPE M P+ AG P+P T + G T+ Q P+P
Sbjct: 15 PGEGGAGEAEPE-MEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLP---- 69
Query: 240 SQEPGPSPEGPM---PLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAE 296
P P P G + P G + +AEE + + A + AA + P P +P
Sbjct: 70 ---PPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPA 126
Query: 297 PE 298
PE
Sbjct: 127 PE 128
>gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens]
Length = 560
Score = 37.0 bits (84), Expect = 0.021
Identities = 35/122 (28%), Positives = 48/122 (39%), Gaps = 17/122 (13%)
Query: 186 PHPRGAFMLEPEGMSPM--EPAGVSPMPGTQKDT----GRTEEQPMEVSVCRSPVPALGF 239
P GA EPE M P+ AG P+P T + G T+ Q P+P
Sbjct: 15 PGEGGAGEAEPE-MEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLP---- 69
Query: 240 SQEPGPSPEGPM---PLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAE 296
P P P G + P G + +AEE + + A + AA + P P +P
Sbjct: 70 ---PPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPA 126
Query: 297 PE 298
PE
Sbjct: 127 PE 128
>gi|28559071 DNA cytosine methyltransferase 3 alpha isoform c [Homo
sapiens]
Length = 166
Score = 36.2 bits (82), Expect = 0.036
Identities = 32/104 (30%), Positives = 44/104 (42%), Gaps = 18/104 (17%)
Query: 198 GMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPMPLG--- 254
G +P +PA +S P +D+G +E +P + P PE P G
Sbjct: 63 GDTPKDPAVISKSPSMAQDSGASE-----------LLPNGDLEKRSEPQPEEGSPAGGQK 111
Query: 255 GGEDEDAEEAVE-LPEAS--APKAALEPKESR-SPQQVGPTWRP 294
GG + E A E LPEAS PKE R +P + G + P
Sbjct: 112 GGAPAEGEGAAETLPEASRAVENGCCTPKEGRGAPAEAGESSAP 155
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 36.2 bits (82), Expect = 0.036
Identities = 31/105 (29%), Positives = 38/105 (36%), Gaps = 12/105 (11%)
Query: 201 PMEPAGVSPMPGTQKDTGRTEEQPMEV----SVCRSPVPA---LGFSQEPGPSPEGPMPL 253
P P P P D + + P V S SP P G+ E SPEG P
Sbjct: 779 PPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPG 838
Query: 254 GGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEPE 298
GG +E+ +P AP +P R P GP P E
Sbjct: 839 GGAAEEEG-----VPRPRAPPEPPDPGAPRPPPDPGPLPLPGPRE 878
Score = 29.6 bits (65), Expect = 3.4
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 12/79 (15%)
Query: 202 MEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPMPLGGGEDEDA 261
+ P ++P PG P E + + G + PGP+ E GEDED
Sbjct: 1264 LPPLTLTPFPGPGP-----RRPPWEGADAGAAGGEAGGAGAPGPAEED------GEDEDE 1312
Query: 262 EEAVELPEASAPKAALEPK 280
+E E EA+AP AA P+
Sbjct: 1313 DEE-EDEEAAAPGAAAGPR 1330
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 36.2 bits (82), Expect = 0.036
Identities = 32/147 (21%), Positives = 55/147 (37%), Gaps = 16/147 (10%)
Query: 143 LIIPLLPMALVAPDEMEKNNNPLYSRQGEVLASRKDFRMNTCVPHPRGAFMLEPEGMSPM 202
+++ LL +AL+A + N + + L + N P P+G + P
Sbjct: 1 MLLILLSVALLALSSAQNLNEDVSQEESPSLIAG-----NPQGPSPQGGNKPQGPPPPPG 55
Query: 203 EPAGVSPMPGTQKD----TGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPMPLGGGED 258
+P G P G + G+ + P + RSP + P P+GP P GG +
Sbjct: 56 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP-------RSPPGKPQGPPPQGGNQP 108
Query: 259 EDAEEAVELPEASAPKAALEPKESRSP 285
+ P+ P+ P+ P
Sbjct: 109 QGPPPPPGKPQGPPPQGGNRPQGPPPP 135
Score = 34.3 bits (77), Expect = 0.14
Identities = 24/104 (23%), Positives = 39/104 (37%), Gaps = 11/104 (10%)
Query: 186 PHPRGAFMLEPEGMSPMEPAGVSPMPGTQKD----TGRTEEQPMEVSVCRSPVPALGFSQ 241
P P+G + P +P G P G + G+ + P + RSP +
Sbjct: 100 PPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSP-------R 152
Query: 242 EPGPSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSP 285
P P+GP P GG + + P+ P+ +P+ P
Sbjct: 153 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPP 196
Score = 34.3 bits (77), Expect = 0.14
Identities = 28/115 (24%), Positives = 44/115 (38%), Gaps = 13/115 (11%)
Query: 186 PHPRGAFMLEPEGMSPMEPAGVSPMPGTQKD----TGRTEEQPMEVSVCRSPVPALGFSQ 241
P P+G + P +P G P G + G+ + P + RS SQ
Sbjct: 161 PPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRS-------SQ 213
Query: 242 EPGPSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAE 296
P P+GP P GG + + P+ P+ +P+ P + P PA+
Sbjct: 214 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK--PQGPPAQ 266
Score = 32.0 bits (71), Expect = 0.68
Identities = 29/114 (25%), Positives = 43/114 (37%), Gaps = 17/114 (14%)
Query: 186 PHPRGAFMLEPEGMSPMEPAGVSPMPGTQKD----TGRTEEQPME-----VSVCRSPVPA 236
P P+G + P +P G P G + G+ + P + S P
Sbjct: 222 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKP 281
Query: 237 LGFSQEPGPSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEP----KESRSPQ 286
G Q+ G +P+GP P GG + + P A P+ P + SR PQ
Sbjct: 282 QGPPQQEGNNPQGPPPPAGGNPQQP----QAPPAGQPQGPPRPPQGGRPSRPPQ 331
Score = 29.3 bits (64), Expect = 4.4
Identities = 30/117 (25%), Positives = 39/117 (33%), Gaps = 11/117 (9%)
Query: 186 PHPRGAFMLEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGP 245
P P G +P+G P SP K G P + + P P G Q P P
Sbjct: 132 PPPPG----KPQGPPPQGDKSRSPRSPPGKPQG---PPPQGGNQPQGPPPPPGKPQGPPP 184
Query: 246 S----PEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEPE 298
P+GP P G + + S P P Q GP P +P+
Sbjct: 185 QGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 241
Score = 28.9 bits (63), Expect = 5.8
Identities = 30/117 (25%), Positives = 39/117 (33%), Gaps = 11/117 (9%)
Query: 186 PHPRGAFMLEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGP 245
P P G +P+G P SP K G P + + P P G Q P P
Sbjct: 71 PPPPG----KPQGPPPQGDKSRSPRSPPGKPQG---PPPQGGNQPQGPPPPPGKPQGPPP 123
Query: 246 S----PEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEPE 298
P+GP P G + + S P P Q GP P +P+
Sbjct: 124 QGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 180
Score = 28.1 bits (61), Expect = 9.8
Identities = 25/112 (22%), Positives = 40/112 (35%), Gaps = 19/112 (16%)
Query: 201 PMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGP---SPEGPMPLGGGE 257
P +P G P G Q + P + P P G + P P+GP GG +
Sbjct: 216 PGKPQGPPPQGGNQP-----QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSK 270
Query: 258 DEDA-----------EEAVELPEASAPKAALEPKESRSPQQVGPTWRPAEPE 298
+ A ++ P+ P A P++ ++P P P P+
Sbjct: 271 SQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQ 322
>gi|144922631 tigger transposable element derived 5 [Homo sapiens]
Length = 593
Score = 35.8 bits (81), Expect = 0.047
Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 13/71 (18%)
Query: 230 CRSPV-PALGFSQEPGPSPEGPMPLGGGEDEDAEEAVELPEASAPKA---------ALEP 279
CR V PAL + P P+ P +GGGEDE EEA + S P A AL
Sbjct: 496 CREEVGPALPPAAPPAPASL-PSAMGGGEDE--EEATDYGGTSVPTAGEAVRGLETALRW 552
Query: 280 KESRSPQQVGP 290
E++ P++VGP
Sbjct: 553 LENQDPREVGP 563
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 35.4 bits (80), Expect = 0.061
Identities = 32/111 (28%), Positives = 44/111 (39%), Gaps = 11/111 (9%)
Query: 196 PEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEV-SVCRSPVPALGFSQEPGPSPEGPMPLG 254
PE + P P+P +K E P +V V + VP + P PE P P
Sbjct: 10610 PEAPKEVVPEKKVPVPPPKKP----EVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEV 10665
Query: 255 GGEDEDAE------EAVELPEASAPKAALEPKESRSPQQVGPTWRPAEPEL 299
E E+ E VE PE +AP P + P++ P +PEL
Sbjct: 10666 FEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPEL 10716
Score = 30.0 bits (66), Expect = 2.6
Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 4/117 (3%)
Query: 185 VPHPRGAFMLEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRS-PVPALGFSQEP 243
VP + +L P+ + P + V P + + E P EV + PVP + P
Sbjct: 10490 VPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVP 10549
Query: 244 GPSPEGPMPLGGGEDEDAEEAVE-LPEASAPKAALEPKESRSPQQVGPTWRPAEPEL 299
P+ +P ++ EA+ PE+ P+ PKE P++ P P +PE+
Sbjct: 10550 -PTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEV-VPEKKVPAAPPKKPEV 10604
>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
sapiens]
Length = 1632
Score = 35.4 bits (80), Expect = 0.061
Identities = 27/91 (29%), Positives = 39/91 (42%), Gaps = 5/91 (5%)
Query: 203 EPAGVSPMPGTQKDTGRTEEQPMEV-SVCRSPVPALGFSQEPGPSPEGPMPLGGGEDEDA 261
EP T+K+ R E++ + S + P P +EP E + EDED
Sbjct: 237 EPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEP--DREARAGVQADEDEDG 294
Query: 262 EEAVELPEASAPK--AALEPKESRSPQQVGP 290
+E E S PK AA E + P++V P
Sbjct: 295 DEKDEKKHRSQPKDLAAKRRPEEKEPEKVNP 325
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 35.4 bits (80), Expect = 0.061
Identities = 27/91 (29%), Positives = 39/91 (42%), Gaps = 5/91 (5%)
Query: 203 EPAGVSPMPGTQKDTGRTEEQPMEV-SVCRSPVPALGFSQEPGPSPEGPMPLGGGEDEDA 261
EP T+K+ R E++ + S + P P +EP E + EDED
Sbjct: 221 EPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEP--DREARAGVQADEDEDG 278
Query: 262 EEAVELPEASAPK--AALEPKESRSPQQVGP 290
+E E S PK AA E + P++V P
Sbjct: 279 DEKDEKKHRSQPKDLAAKRRPEEKEPEKVNP 309
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,449,616
Number of Sequences: 37866
Number of extensions: 797841
Number of successful extensions: 3795
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 331
Number of HSP's that attempted gapping in prelim test: 3425
Number of HSP's gapped (non-prelim): 634
length of query: 299
length of database: 18,247,518
effective HSP length: 102
effective length of query: 197
effective length of database: 14,385,186
effective search space: 2833881642
effective search space used: 2833881642
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.