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Search of human proteins with 14589933
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens]
(1072 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens] 2131 0.0
gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens] 2105 0.0
gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens] 1957 0.0
gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens] 968 0.0
gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens] 967 0.0
gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens] 694 0.0
gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens] 694 0.0
gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens] 607 e-173
gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens] 607 e-173
gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens] 607 e-173
gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo s... 605 e-173
gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens] 605 e-173
gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens] 605 e-173
gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo ... 605 e-173
gi|190194360 protocadherin 20 [Homo sapiens] 405 e-112
gi|14270499 protocadherin gamma subfamily B, 4 isoform 2 precurs... 336 8e-92
gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precurs... 336 8e-92
gi|14270508 protocadherin gamma subfamily B, 7 isoform 2 precurs... 330 6e-90
gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precurs... 330 6e-90
gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precurs... 322 1e-87
gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs... 322 1e-87
gi|11128029 protocadherin gamma subfamily B, 6 isoform 1 precurs... 321 2e-87
gi|14270502 protocadherin gamma subfamily B, 6 isoform 2 precurs... 321 2e-87
gi|16933557 dachsous 1 precursor [Homo sapiens] 320 6e-87
gi|14270505 protocadherin gamma subfamily B, 5 isoform 2 precurs... 317 3e-86
gi|11128031 protocadherin gamma subfamily B, 5 isoform 1 precurs... 317 3e-86
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 315 1e-85
gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 315 1e-85
gi|11036656 protocadherin beta 7 precursor [Homo sapiens] 312 9e-85
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 312 1e-84
>gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens]
Length = 1072
Score = 2131 bits (5522), Expect = 0.0
Identities = 1072/1072 (100%), Positives = 1072/1072 (100%)
Query: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60
MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG
Sbjct: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60
Query: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120
SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS
Sbjct: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120
Query: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180
QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY
Sbjct: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180
Query: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240
ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR
Sbjct: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240
Query: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITD 300
SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITD
Sbjct: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITD 300
Query: 301 VNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL 360
VNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL
Sbjct: 301 VNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL 360
Query: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420
DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI
Sbjct: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420
Query: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480
GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ
Sbjct: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480
Query: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540
NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV
Sbjct: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540
Query: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600
EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE
Sbjct: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600
Query: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660
QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM
Sbjct: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660
Query: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720
VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP
Sbjct: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720
Query: 721 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN 780
PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN
Sbjct: 721 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN 780
Query: 781 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN 840
YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN
Sbjct: 781 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN 840
Query: 841 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM 900
ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM
Sbjct: 841 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM 900
Query: 901 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN 960
ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN
Sbjct: 901 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN 960
Query: 961 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA 1020
GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA
Sbjct: 961 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA 1020
Query: 1021 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQVRCIPNIFKYPREG 1072
VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQVRCIPNIFKYPREG
Sbjct: 1021 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQVRCIPNIFKYPREG 1072
>gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens]
Length = 1069
Score = 2105 bits (5453), Expect = 0.0
Identities = 1061/1065 (99%), Positives = 1062/1065 (99%)
Query: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60
MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG
Sbjct: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60
Query: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120
SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS
Sbjct: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120
Query: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180
QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY
Sbjct: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180
Query: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240
ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR
Sbjct: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240
Query: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITD 300
SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITD
Sbjct: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITD 300
Query: 301 VNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL 360
VNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL
Sbjct: 301 VNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL 360
Query: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420
DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI
Sbjct: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420
Query: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480
GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ
Sbjct: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480
Query: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540
NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV
Sbjct: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540
Query: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600
EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE
Sbjct: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600
Query: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660
QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM
Sbjct: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660
Query: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720
VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP
Sbjct: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720
Query: 721 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN 780
PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN
Sbjct: 721 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN 780
Query: 781 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN 840
YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN
Sbjct: 781 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN 840
Query: 841 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM 900
ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM
Sbjct: 841 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM 900
Query: 901 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN 960
ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN
Sbjct: 901 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN 960
Query: 961 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA 1020
GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA
Sbjct: 961 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA 1020
Query: 1021 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQVRCIPNI 1065
VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQ+R P I
Sbjct: 1021 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQMRLHPYI 1065
>gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens]
Length = 1200
Score = 1957 bits (5071), Expect = 0.0
Identities = 1000/1058 (94%), Positives = 1002/1058 (94%), Gaps = 47/1058 (4%)
Query: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60
MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG
Sbjct: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60
Query: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120
SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS
Sbjct: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120
Query: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180
QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY
Sbjct: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180
Query: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240
ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR
Sbjct: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240
Query: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITD 300
SSVFELQ V D D + Q I+
Sbjct: 241 SSVFELQ--------------------------------VADTPDGEKQPQLIV------ 262
Query: 301 VNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL 360
K VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL
Sbjct: 263 ---------KGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL 313
Query: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420
DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI
Sbjct: 314 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 373
Query: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480
GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ
Sbjct: 374 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 433
Query: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540
NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV
Sbjct: 434 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 493
Query: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600
EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE
Sbjct: 494 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 553
Query: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660
QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM
Sbjct: 554 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 613
Query: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720
VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP
Sbjct: 614 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 673
Query: 721 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN 780
PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN
Sbjct: 674 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN 733
Query: 781 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN 840
YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN
Sbjct: 734 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN 793
Query: 841 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM 900
ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM
Sbjct: 794 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM 853
Query: 901 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN 960
ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN
Sbjct: 854 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN 913
Query: 961 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA 1020
GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA
Sbjct: 914 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA 973
Query: 1021 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQ 1058
VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQ
Sbjct: 974 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQ 1011
>gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens]
Length = 1060
Score = 968 bits (2503), Expect = 0.0
Identities = 524/1048 (50%), Positives = 706/1048 (67%), Gaps = 66/1048 (6%)
Query: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSGEVTFSLESGSEYLKID 78
LLL L+ S A +++ Y++ EE P + IG++A+D G G + + LE G+ YL++D
Sbjct: 46 LLLLLAPSPGHATRVV-YKVPEEQPPNTLIGSLAADYGF-PDVGHL-YKLEVGAPYLRVD 102
Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVD-LFEGQVIVLDIN 137
TG++ T+E IDRE L +CQ + C L+FEVS+ Q+ L EGQ+ V DIN
Sbjct: 103 GKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDIN 162
Query: 138 DNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRR 197
DNTP F SPV+TL + EN +G+L+ +P A+DRD G NG+ YEL P
Sbjct: 163 DNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGP----------- 211
Query: 198 AGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQ 257
+A E +F LQVA+ + EKQ
Sbjct: 212 -----------------------------EAQE------------LFGLQVAEDQE-EKQ 229
Query: 258 PQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317
PQLIV G LDRE+ DSY+LT++V+DGG PPR+S A+LRV + D NDN+P+FE+ YEA+L
Sbjct: 230 PQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAEL 289
Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREE 377
+ENS G ++Q++A D D G N +IEY F A E VRRLLRLD +G ++V +DRE+
Sbjct: 290 SENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDRED 349
Query: 378 VNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVL 437
++ LRF+V+A+DRG PK+ +A VV+ +KD NDN P+IEIR IG + +DG+AN++EDV
Sbjct: 350 LSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVA 409
Query: 438 VDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEA 497
+T +ALVQVSDRD+GEN VTC V GDVPFQL+ AS+T G +KKKYFL T+TPLDYE
Sbjct: 410 EETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASET-GSDSKKKYFLQTTTPLDYEK 468
Query: 498 TREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATV 557
+++ + IVAVDSG+P LSS NSL V+V D NDN P+F QSV EV FPENN PGE +A +
Sbjct: 469 VKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEI 528
Query: 558 LATDADSGKNAEIAYSLDS--SVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKG 615
A+DADSG NAE+ YSL+ + G+F I P++G+I V T LDREQ + YE KV A D+G
Sbjct: 529 TASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRG 588
Query: 616 IPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMS 675
P LQG+ TV+V V D NDNDPKFM + F V EN+ SPVGMVTV+D DKG NA++
Sbjct: 589 SPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQ 648
Query: 676 LYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDE 735
L +E++N F I+N TGTI S++SFDRE Q+TYTF++KAVDGG PPRSA V++ V+DE
Sbjct: 649 LSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDE 708
Query: 736 NDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEID 795
NDNAP +T P N S+ LL P + + V+ V A D D G+NA+L YSI GGNP+ LF+I
Sbjct: 709 NDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIG 768
Query: 796 PTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIAR 855
SG ++L ++ ++H+GLHRLVV+V+D G+P + T LVH++VNE+++N T +++ +
Sbjct: 769 SHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGH 828
Query: 856 SLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN-KNGYEA 914
SL PL DIAGDP YE SKQR +I+ GVVAG++ V L+I + V+ RYCR + K+GY+A
Sbjct: 829 SLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQA 888
Query: 915 GKKDHEDFFTPQQHDKSKKPKKDK-KNKKSKQPLYSSIVTVEASKPNGQRYDSVNEKLSD 973
GKK+ +D + P+ K+ K K K K KS +P+ EA +++ +++ D
Sbjct: 889 GKKETKDLYAPKPSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPGD 948
Query: 974 SPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033
SP + + +N PGSPDL RHY+S+SPLP++QL PQSP+A KKHQ VQDLPPANTFVG
Sbjct: 949 SPRI--HLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGT 1006
Query: 1034 GDNISIGSDHCSEYSCQTN-NKY-SKQV 1059
GD S GS+ S+YS +TN KY SKQV
Sbjct: 1007 GDTTSTGSEQYSDYSYRTNPPKYPSKQV 1034
>gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens]
Length = 1237
Score = 967 bits (2500), Expect = 0.0
Identities = 523/1048 (49%), Positives = 706/1048 (67%), Gaps = 66/1048 (6%)
Query: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSGEVTFSLESGSEYLKID 78
LLL L+ S A +++ Y++ EE P + IG++A+D G G + + LE G+ YL++D
Sbjct: 46 LLLLLAPSPGHATRVV-YKVPEEQPPNTLIGSLAADYGF-PDVGHL-YKLEVGAPYLRVD 102
Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVD-LFEGQVIVLDIN 137
TG++ T+E IDRE L +CQ + C L+FEVS+ Q+ L EGQ+ V DIN
Sbjct: 103 GKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDIN 162
Query: 138 DNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRR 197
DNTP F SPV+TL + EN +G+L+ +P A+DRD G NG+ YEL P
Sbjct: 163 DNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGP----------- 211
Query: 198 AGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQ 257
+A E +F LQVA+ + EKQ
Sbjct: 212 -----------------------------EAQE------------LFGLQVAEDQE-EKQ 229
Query: 258 PQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317
PQLIV G LDRE+ DSY+LT++V+DGG PPR+S A+LRV + D NDN+P+FE+ YEA+L
Sbjct: 230 PQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAEL 289
Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREE 377
+ENS G ++Q++A D D G N +IEY F A E VRRLLRLD +G ++V +DRE+
Sbjct: 290 SENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDRED 349
Query: 378 VNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVL 437
++ LRF+V+A+DRG PK+ +A VV+ +KD NDN P+IEIR IG + +DG+AN++EDV
Sbjct: 350 LSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVA 409
Query: 438 VDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEA 497
+T +ALVQVSDRD+GEN VTC V GDVPFQL+ AS+T G +KKKYFL T+TPLDYE
Sbjct: 410 EETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASET-GSDSKKKYFLQTTTPLDYEK 468
Query: 498 TREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATV 557
+++ + IVAVDSG+P LSS NSL V+V D NDN P+F QSV EV FPENN PGE +A +
Sbjct: 469 VKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEI 528
Query: 558 LATDADSGKNAEIAYSLDS--SVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKG 615
A+DADSG NAE+ YSL+ + G+F I P++G+I V T LDREQ + YE KV A D+G
Sbjct: 529 TASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRG 588
Query: 616 IPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMS 675
P LQG+ TV+V V D NDNDPKFM + F V EN+ SPVGMVTV+D DKG NA++
Sbjct: 589 SPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQ 648
Query: 676 LYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDE 735
L +E++N F I+N TGTI S++SFDRE Q+TYTF++KAVDGG PPRSA V++ V+DE
Sbjct: 649 LSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDE 708
Query: 736 NDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEID 795
NDNAP +T P N S+ LL P + + V+ V A D D G+NA+L YSI GGNP+ LF+I
Sbjct: 709 NDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIG 768
Query: 796 PTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIAR 855
SG ++L ++ ++H+GLHRLVV+V+D G+P + T LVH++VNE+++N T +++ +
Sbjct: 769 SHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGH 828
Query: 856 SLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN-KNGYEA 914
SL PL DIAGDP YE SKQR +I+ GVVAG++ V L+I + V+ RYCR + K+GY+A
Sbjct: 829 SLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQA 888
Query: 915 GKKDHEDFFTPQQHDKSKKPKKDK-KNKKSKQPLYSSIVTVEASKPNGQRYDSVNEKLSD 973
GKK+ +D + P+ K+ K K K K KS +P+ EA +++ +++ D
Sbjct: 889 GKKETKDLYAPKPSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPGD 948
Query: 974 SPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033
SP + + +N PGSPDL RHY+S+SPLP++QL PQSP+A KKHQ VQDLPPANTFVG
Sbjct: 949 SPRI--HLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGT 1006
Query: 1034 GDNISIGSDHCSEYSCQTN-NKY-SKQV 1059
GD S GS+ S+YS +TN KY SKQ+
Sbjct: 1007 GDTTSTGSEQYSDYSYRTNPPKYPSKQL 1034
>gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens]
Length = 1203
Score = 694 bits (1792), Expect = 0.0
Identities = 425/1071 (39%), Positives = 603/1071 (56%), Gaps = 98/1071 (9%)
Query: 11 RGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-----VTG-SGEV 64
R + L L+ L L A A++L+ Y + EE P +V IGN+ DL I TG S +
Sbjct: 4 RDFYLLAALIACLRLDSAIAQELI-YTIREELPENVPIGNIPKDLNISHINAATGTSASL 62
Query: 65 TFSLES---GSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQ 121
+ L S + +K+ + TGE+ T+ RIDREKL +ENECF + EV ++
Sbjct: 63 VYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVIL--PN 120
Query: 122 SWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYE 181
+ L + ++IV D NDN P FPSPV+ +++ EN + + + +P+ATD
Sbjct: 121 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATD------------ 168
Query: 182 LLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRS 241
P G NG + + G
Sbjct: 169 -------------------------PDTGFNGV---------QHYELLNG---------Q 185
Query: 242 SVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDV 301
SVF L + +TP+GEK PQLIV+ LDREQ+D+Y + ++V DGG P +SS AIL+V ++DV
Sbjct: 186 SVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDV 245
Query: 302 NDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGA-ATESVRRLLRL 360
NDN P F++ E + EN+ GT ++QL A D D+G N +I Y+FGA + +RL L
Sbjct: 246 NDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFAL 305
Query: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420
+ T+G ++V +DREE + TV+A D P +ATV +N+ D NDN P+I++R I
Sbjct: 306 NNTTGLITVQRSLDREETAIHKVTVLASDGSSTPA--RATVTINVTDVNDNPPNIDLRYI 363
Query: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480
I +G ++E V+T IAL+ VSD+D NG V C + +VPF LK D +
Sbjct: 364 --ISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQ--- 418
Query: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540
Y L TS+ LDYE T+EF+ IVA DSG PSL+ + VK+ D NDNPP+F Q V+
Sbjct: 419 ----YLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVI 474
Query: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600
E+ ENN G + T+ ATD DSGKNA+I Y L + F +D +G + + V DRE
Sbjct: 475 ELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDRE 533
Query: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660
+ +R+ F V A+D G P LQ VIV V D+NDN PKF + F F+V ENL S VG+
Sbjct: 534 EQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGV 593
Query: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720
+TV DAD G N ++L I +N+ F ++ +G I S +SFDRE Q++YTF VKA DGG P
Sbjct: 594 ITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQP 653
Query: 721 PRSATATVSLFVMDENDNAPTV-TLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADL 779
PRS+TA V++ VMD NDN+P V + P N S+ L+P S+ +VVA V A D D G+NA+L
Sbjct: 654 PRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAEL 713
Query: 780 NYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVF 838
Y+IV GN LF IDP +G ++L K GLHRLVV ++D G P S T LV ++
Sbjct: 714 KYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLY 773
Query: 839 VNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIV 898
VN++ NA+ I I R++ PL ++I ++ L+I+I ++AG M VI++I +
Sbjct: 774 VNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVT 833
Query: 899 VMARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASK 958
V+ R CR ++ K ++ +P Q +K K KK KK K K L + VT+E SK
Sbjct: 834 VLVR-CRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLL-NFVTIEESK 891
Query: 959 PNGQRYDSVNEKLS-----DSPSMGRY-----RSVNGGPGSPDLARHYKSSSPLPTVQLH 1008
P+ ++ +N +S + S+GR+ P SPDLA+HYKS+SP P L
Sbjct: 892 PDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLK 951
Query: 1009 PQSPTAGKKHQAVQDLPPANTFVGAGDNI----SIGSDHCSEYSCQTNNKY 1055
P +P + KKH +Q+LP NTFVG D + S SDH S C + +
Sbjct: 952 PDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGF 1002
>gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens]
Length = 1237
Score = 694 bits (1792), Expect = 0.0
Identities = 425/1071 (39%), Positives = 603/1071 (56%), Gaps = 98/1071 (9%)
Query: 11 RGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-----VTG-SGEV 64
R + L L+ L L A A++L+ Y + EE P +V IGN+ DL I TG S +
Sbjct: 4 RDFYLLAALIACLRLDSAIAQELI-YTIREELPENVPIGNIPKDLNISHINAATGTSASL 62
Query: 65 TFSLES---GSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQ 121
+ L S + +K+ + TGE+ T+ RIDREKL +ENECF + EV ++
Sbjct: 63 VYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVIL--PN 120
Query: 122 SWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYE 181
+ L + ++IV D NDN P FPSPV+ +++ EN + + + +P+ATD
Sbjct: 121 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATD------------ 168
Query: 182 LLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRS 241
P G NG + + G
Sbjct: 169 -------------------------PDTGFNGV---------QHYELLNG---------Q 185
Query: 242 SVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDV 301
SVF L + +TP+GEK PQLIV+ LDREQ+D+Y + ++V DGG P +SS AIL+V ++DV
Sbjct: 186 SVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDV 245
Query: 302 NDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGA-ATESVRRLLRL 360
NDN P F++ E + EN+ GT ++QL A D D+G N +I Y+FGA + +RL L
Sbjct: 246 NDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFAL 305
Query: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420
+ T+G ++V +DREE + TV+A D P +ATV +N+ D NDN P+I++R I
Sbjct: 306 NNTTGLITVQRSLDREETAIHKVTVLASDGSSTPA--RATVTINVTDVNDNPPNIDLRYI 363
Query: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480
I +G ++E V+T IAL+ VSD+D NG V C + +VPF LK D +
Sbjct: 364 --ISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQ--- 418
Query: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540
Y L TS+ LDYE T+EF+ IVA DSG PSL+ + VK+ D NDNPP+F Q V+
Sbjct: 419 ----YLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVI 474
Query: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600
E+ ENN G + T+ ATD DSGKNA+I Y L + F +D +G + + V DRE
Sbjct: 475 ELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDRE 533
Query: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660
+ +R+ F V A+D G P LQ VIV V D+NDN PKF + F F+V ENL S VG+
Sbjct: 534 EQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGV 593
Query: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720
+TV DAD G N ++L I +N+ F ++ +G I S +SFDRE Q++YTF VKA DGG P
Sbjct: 594 ITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQP 653
Query: 721 PRSATATVSLFVMDENDNAPTV-TLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADL 779
PRS+TA V++ VMD NDN+P V + P N S+ L+P S+ +VVA V A D D G+NA+L
Sbjct: 654 PRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAEL 713
Query: 780 NYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVF 838
Y+IV GN LF IDP +G ++L K GLHRLVV ++D G P S T LV ++
Sbjct: 714 KYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLY 773
Query: 839 VNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIV 898
VN++ NA+ I I R++ PL ++I ++ L+I+I ++AG M VI++I +
Sbjct: 774 VNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVT 833
Query: 899 VMARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASK 958
V+ R CR ++ K ++ +P Q +K K KK KK K K L + VT+E SK
Sbjct: 834 VLVR-CRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLL-NFVTIEESK 891
Query: 959 PNGQRYDSVNEKLS-----DSPSMGRY-----RSVNGGPGSPDLARHYKSSSPLPTVQLH 1008
P+ ++ +N +S + S+GR+ P SPDLA+HYKS+SP P L
Sbjct: 892 PDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLK 951
Query: 1009 PQSPTAGKKHQAVQDLPPANTFVGAGDNI----SIGSDHCSEYSCQTNNKY 1055
P +P + KKH +Q+LP NTFVG D + S SDH S C + +
Sbjct: 952 PDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGF 1002
>gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens]
Length = 1340
Score = 607 bits (1564), Expect = e-173
Identities = 383/1033 (37%), Positives = 571/1033 (55%), Gaps = 95/1033 (9%)
Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Y + EE P +V IGN+ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 60 YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 119
Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 120 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 175
Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
+ +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P
Sbjct: 176 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 225
Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267
G + +L V D E++ ++K
Sbjct: 226 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 250
Query: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327
++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT +
Sbjct: 251 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 300
Query: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386
QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+
Sbjct: 301 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 360
Query: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446
A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+
Sbjct: 361 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 416
Query: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506
V+D+D NG VTC ++PF+L+P + + L + LDYE+T+E+ + ++
Sbjct: 417 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLENAAYLDYESTKEYAIKLL 469
Query: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566
A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V ATDADSG
Sbjct: 470 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGP 529
Query: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626
NAEI Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV
Sbjct: 530 NAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 589
Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686
V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+
Sbjct: 590 VSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 649
Query: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745
I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P
Sbjct: 650 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 709
Query: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805
N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+
Sbjct: 710 YNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 769
Query: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864
K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S+ P+T +
Sbjct: 770 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPN 829
Query: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924
+ + I++ VAG +TV+++I I + R CR + ++ T
Sbjct: 830 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNMQNSEWAT 888
Query: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977
P ++ K KK KK P L ++VT+E +K + D L + +M
Sbjct: 889 PNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 948
Query: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033
G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A
Sbjct: 949 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFV-A 1006
Query: 1034 GDNISIGSDHCSE 1046
D+IS S S+
Sbjct: 1007 CDSISNCSSSSSD 1019
>gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens]
Length = 1048
Score = 607 bits (1564), Expect = e-173
Identities = 383/1033 (37%), Positives = 571/1033 (55%), Gaps = 95/1033 (9%)
Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Y + EE P +V IGN+ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 60 YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 119
Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 120 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 175
Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
+ +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P
Sbjct: 176 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 225
Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267
G + +L V D E++ ++K
Sbjct: 226 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 250
Query: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327
++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT +
Sbjct: 251 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 300
Query: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386
QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+
Sbjct: 301 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 360
Query: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446
A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+
Sbjct: 361 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 416
Query: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506
V+D+D NG VTC ++PF+L+P + + L + LDYE+T+E+ + ++
Sbjct: 417 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLENAAYLDYESTKEYAIKLL 469
Query: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566
A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V ATDADSG
Sbjct: 470 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGP 529
Query: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626
NAEI Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV
Sbjct: 530 NAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 589
Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686
V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+
Sbjct: 590 VSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 649
Query: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745
I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P
Sbjct: 650 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 709
Query: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805
N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+
Sbjct: 710 YNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 769
Query: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864
K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S+ P+T +
Sbjct: 770 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPN 829
Query: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924
+ + I++ VAG +TV+++I I + R CR + ++ T
Sbjct: 830 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNMQNSEWAT 888
Query: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977
P ++ K KK KK P L ++VT+E +K + D L + +M
Sbjct: 889 PNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 948
Query: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033
G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A
Sbjct: 949 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFV-A 1006
Query: 1034 GDNISIGSDHCSE 1046
D+IS S S+
Sbjct: 1007 CDSISNCSSSSSD 1019
>gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens]
Length = 1037
Score = 607 bits (1564), Expect = e-173
Identities = 383/1033 (37%), Positives = 571/1033 (55%), Gaps = 95/1033 (9%)
Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Y + EE P +V IGN+ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 49 YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 108
Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 109 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 164
Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
+ +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P
Sbjct: 165 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 214
Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267
G + +L V D E++ ++K
Sbjct: 215 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 239
Query: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327
++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT +
Sbjct: 240 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 289
Query: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386
QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+
Sbjct: 290 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 349
Query: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446
A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+
Sbjct: 350 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 405
Query: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506
V+D+D NG VTC ++PF+L+P + + L + LDYE+T+E+ + ++
Sbjct: 406 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLENAAYLDYESTKEYAIKLL 458
Query: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566
A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V ATDADSG
Sbjct: 459 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGP 518
Query: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626
NAEI Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV
Sbjct: 519 NAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 578
Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686
V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+
Sbjct: 579 VSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 638
Query: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745
I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P
Sbjct: 639 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 698
Query: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805
N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+
Sbjct: 699 YNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 758
Query: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864
K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S+ P+T +
Sbjct: 759 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPN 818
Query: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924
+ + I++ VAG +TV+++I I + R CR + ++ T
Sbjct: 819 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNMQNSEWAT 877
Query: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977
P ++ K KK KK P L ++VT+E +K + D L + +M
Sbjct: 878 PNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 937
Query: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033
G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A
Sbjct: 938 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFV-A 995
Query: 1034 GDNISIGSDHCSE 1046
D+IS S S+
Sbjct: 996 CDSISNCSSSSSD 1008
>gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo
sapiens]
Length = 1021
Score = 605 bits (1560), Expect = e-173
Identities = 382/1033 (36%), Positives = 570/1033 (55%), Gaps = 95/1033 (9%)
Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Y + EE P +V IG++ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 28 YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87
Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 88 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143
Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
+ +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P
Sbjct: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 193
Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267
G + +L V D E++ ++K
Sbjct: 194 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 218
Query: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327
++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT +
Sbjct: 219 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 268
Query: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386
QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+
Sbjct: 269 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 328
Query: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446
A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+
Sbjct: 329 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 384
Query: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506
V+D+D NG VTC ++PF+L+P + + L T+ LDYE+T+E+ + ++
Sbjct: 385 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETAAYLDYESTKEYAIKLL 437
Query: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566
A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V A DADSG
Sbjct: 438 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGP 497
Query: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626
NA+I Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV
Sbjct: 498 NAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 557
Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686
V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+
Sbjct: 558 VSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 617
Query: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745
I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P
Sbjct: 618 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 677
Query: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805
N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+
Sbjct: 678 SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 737
Query: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864
K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S P+T +
Sbjct: 738 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPN 797
Query: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924
+ + I++ VAG +TV+++I I + R CR K + ++ T
Sbjct: 798 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNKQNSEWAT 856
Query: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977
P ++ K KK KK P L + VT+E +K + D L + +M
Sbjct: 857 PNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 916
Query: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033
G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A
Sbjct: 917 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFV-A 974
Query: 1034 GDNISIGSDHCSE 1046
D+IS S S+
Sbjct: 975 CDSISKCSSSSSD 987
>gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens]
Length = 1337
Score = 605 bits (1560), Expect = e-173
Identities = 382/1033 (36%), Positives = 570/1033 (55%), Gaps = 95/1033 (9%)
Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Y + EE P +V IG++ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 28 YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87
Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 88 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143
Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
+ +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P
Sbjct: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 193
Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267
G + +L V D E++ ++K
Sbjct: 194 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 218
Query: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327
++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT +
Sbjct: 219 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 268
Query: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386
QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+
Sbjct: 269 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 328
Query: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446
A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+
Sbjct: 329 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 384
Query: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506
V+D+D NG VTC ++PF+L+P + + L T+ LDYE+T+E+ + ++
Sbjct: 385 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETAAYLDYESTKEYAIKLL 437
Query: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566
A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V A DADSG
Sbjct: 438 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGP 497
Query: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626
NA+I Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV
Sbjct: 498 NAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 557
Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686
V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+
Sbjct: 558 VSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 617
Query: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745
I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P
Sbjct: 618 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 677
Query: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805
N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+
Sbjct: 678 SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 737
Query: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864
K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S P+T +
Sbjct: 738 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPN 797
Query: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924
+ + I++ VAG +TV+++I I + R CR K + ++ T
Sbjct: 798 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNKQNSEWAT 856
Query: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977
P ++ K KK KK P L + VT+E +K + D L + +M
Sbjct: 857 PNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 916
Query: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033
G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A
Sbjct: 917 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFV-A 974
Query: 1034 GDNISIGSDHCSE 1046
D+IS S S+
Sbjct: 975 CDSISKCSSSSSD 987
>gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens]
Length = 1347
Score = 605 bits (1560), Expect = e-173
Identities = 382/1033 (36%), Positives = 570/1033 (55%), Gaps = 95/1033 (9%)
Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Y + EE P +V IG++ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 28 YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87
Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 88 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143
Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
+ +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P
Sbjct: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 193
Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267
G + +L V D E++ ++K
Sbjct: 194 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 218
Query: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327
++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT +
Sbjct: 219 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 268
Query: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386
QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+
Sbjct: 269 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 328
Query: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446
A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+
Sbjct: 329 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 384
Query: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506
V+D+D NG VTC ++PF+L+P + + L T+ LDYE+T+E+ + ++
Sbjct: 385 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETAAYLDYESTKEYAIKLL 437
Query: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566
A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V A DADSG
Sbjct: 438 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGP 497
Query: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626
NA+I Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV
Sbjct: 498 NAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 557
Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686
V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+
Sbjct: 558 VSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 617
Query: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745
I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P
Sbjct: 618 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 677
Query: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805
N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+
Sbjct: 678 SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 737
Query: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864
K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S P+T +
Sbjct: 738 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPN 797
Query: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924
+ + I++ VAG +TV+++I I + R CR K + ++ T
Sbjct: 798 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNKQNSEWAT 856
Query: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977
P ++ K KK KK P L + VT+E +K + D L + +M
Sbjct: 857 PNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 916
Query: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033
G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A
Sbjct: 917 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFV-A 974
Query: 1034 GDNISIGSDHCSE 1046
D+IS S S+
Sbjct: 975 CDSISKCSSSSSD 987
>gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo
sapiens]
Length = 1025
Score = 605 bits (1560), Expect = e-173
Identities = 382/1033 (36%), Positives = 570/1033 (55%), Gaps = 95/1033 (9%)
Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Y + EE P +V IG++ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 28 YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87
Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 88 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143
Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
+ +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P
Sbjct: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 193
Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267
G + +L V D E++ ++K
Sbjct: 194 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 218
Query: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327
++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT +
Sbjct: 219 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 268
Query: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386
QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+
Sbjct: 269 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 328
Query: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446
A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+
Sbjct: 329 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 384
Query: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506
V+D+D NG VTC ++PF+L+P + + L T+ LDYE+T+E+ + ++
Sbjct: 385 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETAAYLDYESTKEYAIKLL 437
Query: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566
A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V A DADSG
Sbjct: 438 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGP 497
Query: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626
NA+I Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV
Sbjct: 498 NAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 557
Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686
V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+
Sbjct: 558 VSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 617
Query: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745
I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P
Sbjct: 618 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 677
Query: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805
N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+
Sbjct: 678 SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 737
Query: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864
K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S P+T +
Sbjct: 738 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPN 797
Query: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924
+ + I++ VAG +TV+++I I + R CR K + ++ T
Sbjct: 798 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNKQNSEWAT 856
Query: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977
P ++ K KK KK P L + VT+E +K + D L + +M
Sbjct: 857 PNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 916
Query: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033
G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A
Sbjct: 917 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFV-A 974
Query: 1034 GDNISIGSDHCSE 1046
D+IS S S+
Sbjct: 975 CDSISKCSSSSSD 987
>gi|190194360 protocadherin 20 [Homo sapiens]
Length = 951
Score = 405 bits (1041), Expect = e-112
Identities = 295/920 (32%), Positives = 451/920 (49%), Gaps = 112/920 (12%)
Query: 26 SLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSG-------------------EVTF 66
S + A +LL Y L E PA V IG++A DL ++ S ++F
Sbjct: 61 SYSRATELL-YSLNEGLPAGVLIGSLAEDLRLLPRSAGRPDPQSQLPERTGAEWNPPLSF 119
Query: 67 SLES---GSEYLKIDNLTGELSTSERRIDREKL------------PQCQMIFDENECFLD 111
SL S +Y+ +DN +GEL TS + IDRE L + C L
Sbjct: 120 SLASRGLSGQYVTLDNRSGELHTSAQEIDREALCVEGGGGTAWSGSVSISSSPSDSCLLL 179
Query: 112 FEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRD 171
+V V+ Q + + ++ + DINDN P FP +++ V EN PV T
Sbjct: 180 LDVLVL--PQEYFRFVKVKIAIRDINDNAPQFPVSQISVWVPENAPVNT----------- 226
Query: 172 FGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEG 231
R A P G NG + R LD
Sbjct: 227 -------------------------RLAIEHPAVDPDVGINGVQ------TYRLLDYH-- 253
Query: 232 GGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQ 291
+F L V + +GE+ P LIV GALDRE +D Y + DGG PP
Sbjct: 254 ----------GMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGGSPPLLGS 303
Query: 292 AILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAAT 351
A L + I+D+NDN P F S + N+ GTPI ++A D D+G N QI Y +
Sbjct: 304 ATLTIGISDINDNCPLFTDSQINVTVYGNATVGTPIAAVQAVDKDLGTNAQITYSYSQKV 363
Query: 352 -ESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDEND 410
++ + L LDE +G + + +I + + T++A G P T +++I
Sbjct: 364 PQASKDLFHLDENTGVIKLFSKIGGSVLESHKLTILANGPGCIPAV--ITALVSIIKVIF 421
Query: 411 NVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQL 470
P I R I DGV + E V+TPIA + RD V C + G+ PF+L
Sbjct: 422 RPPEIVPRYIANEI--DGVVYLKELEPVNTPIAFFTI--RDPEGKYKVNCYLDGEGPFRL 477
Query: 471 KPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTND 530
P + Y L T+ P+DYE + + V +VA +S + V++ D ND
Sbjct: 478 SPYKPYNNE-----YLLETTKPMDYELQQFYEVAVVAWNS--EGFHVKRVIKVQLLDDND 530
Query: 531 NPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGD 590
N P+F Q ++E+ ENN P + + ATDADS + +++Y L F++D +G
Sbjct: 531 NAPIFLQPLIELTIEENNSPNAFLTKLYATDADSEERGQVSYFLGPDAPSYFSLDSVTGI 590
Query: 591 ILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKE 650
+ V+T LDRE+ ++Y + V A D G P + TV + V DKNDN P+F+ F+F+V E
Sbjct: 591 LTVSTQLDREEKEKYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINKDFSFFVPE 650
Query: 651 NLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTF 710
N +G+++V DAD GRN ++L + ++IF I+ G + + +S DRE Q++YT
Sbjct: 651 NFPGYGEIGVISVTDADAGRNGWVALSVVNQSDIFVIDTGKGMLRAKVSLDREQQSSYTL 710
Query: 711 RVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPK-NISYTLLPPSSNVRTVVATVLAT 769
V+AVDGG+P S+TA +++ ++D NDN P V P+ N+SY L+ PS+ + V V A
Sbjct: 711 WVEAVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPVTEVYAV 770
Query: 770 DSDDGINADLNYSIVG--GNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP 827
D D G+NA + YSI+G G + F IDP +G ++L L Q YGLHRL+V+V+D G P
Sbjct: 771 DKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYP 830
Query: 828 SQ-STTTLVHVFVNESVSNATAIDSQIARSLHIPLTQ---DIAGDPSYEISKQRLSIVIG 883
+T +V++FVN++VSN + I+S + + I + + I+ +P++ + +
Sbjct: 831 EPLHSTVMVNLFVNDTVSNESYIESLLRKEPEINIEEKEPQISIEPTHRKVESVSCMPTL 890
Query: 884 VVAGIMTVILIILIVVMARY 903
V ++++ I L+ M Y
Sbjct: 891 VALSVISLGSITLVTGMGIY 910
>gi|14270499 protocadherin gamma subfamily B, 4 isoform 2 precursor
[Homo sapiens]
Length = 803
Score = 336 bits (861), Expect = 8e-92
Identities = 230/731 (31%), Positives = 349/731 (47%), Gaps = 101/731 (13%)
Query: 20 LLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYLKID 78
L LSL A + +RYR+ EE P +GN+A+DLG V + S Y +
Sbjct: 19 LFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVS 78
Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDIND 138
+GEL S R +DRE++ + C L+FE P ++ + V + DIND
Sbjct: 79 AESGELLVSSR-LDREEI-----CGKKPACALEFEAVAENP----LNFYHVNVEIEDIND 128
Query: 139 NTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRA 198
+TP F L + E+ GT ++L +A D D G N ++ Y+L
Sbjct: 129 HTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQL---------------- 172
Query: 199 GAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQP 258
+P S+ + +D G K P
Sbjct: 173 -------------------------------------SPSDHFSLINKEKSD---GSKYP 192
Query: 259 QLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLA 318
++++K LDRE++ SY LTL D G PP SS A + VL+TD NDN+P F + VY L+
Sbjct: 193 EMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDVYRVSLS 252
Query: 319 ENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEV 378
EN PGT +LQ+ A D D GVN +I + F A++ + L+ +G ++VL+ +D EEV
Sbjct: 253 ENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQ--FDLNSNTGEITVLNTLDFEEV 310
Query: 379 NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLV 438
+ + ARD G + TV + + DENDN P + + + + + ED +
Sbjct: 311 KEYSIVLEARDGG--GMIAQCTVEVEVIDENDNAPEVIFQSLPNL--------IMEDAEL 360
Query: 439 DTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEAT 498
T IAL++V D+D NG VTC + GDVPF++ +S + Y L T LD E
Sbjct: 361 GTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSS-------RNTYKLVTDAVLDREQN 413
Query: 499 REFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVL 558
E+N+ + A D G P LSS++S+ + +GD NDN P+F QS V+ ENN PG ++ V
Sbjct: 414 PEYNITVTATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVR 473
Query: 559 ATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAK 612
A+D D G N +++Y + +S + +I +SG + D EQ +E + A+
Sbjct: 474 ASDPDLGPNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQAR 533
Query: 613 DKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNSPVGMVTVMD 665
D+G P L + ++ V V D+NDN P+ + V +P V V +D
Sbjct: 534 DQGSPALSANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVTKVVAVD 593
Query: 666 ADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRS 723
AD G NA +S ++ + + +FS+ TG + + + V DGG PP S
Sbjct: 594 ADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLS 653
Query: 724 ATATVSLFVMD 734
ATAT+ L D
Sbjct: 654 ATATLHLVFAD 664
Score = 228 bits (582), Expect = 2e-59
Identities = 175/662 (26%), Positives = 305/662 (46%), Gaps = 58/662 (8%)
Query: 259 QLIVKGALDREQRDSYE--LTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEAD 316
+L+V LDRE+ + L + P + + V I D+ND++P+F ++ +E
Sbjct: 83 ELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHV-NVEIEDINDHTPKFTQNSFELQ 141
Query: 317 LAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW----LSVLHR 372
++E++ PGT + A D D+G N Y + L+ +++ G + +
Sbjct: 142 ISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHF--SLINKEKSDGSKYPEMVLKTP 199
Query: 373 IDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANV 432
+DRE+ T+ A D G PP + A + + + D NDN P + + R+ L
Sbjct: 200 LDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFS-QDVYRVSL------- 251
Query: 433 AEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASD-TEGDQNKKKYFLHTST 491
+E+V T + V +D+D+G N +T F AS T+ D N +
Sbjct: 252 SENVYPGTTVLQVTATDQDEGVNAEIT--------FSFSEASQITQFDLNSNTGEITVLN 303
Query: 492 PLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPP-MFGQSVVEVYFPENNIP 550
LD+E +E+++V+ A D G + + ++ V+V D NDN P + QS+ + + +
Sbjct: 304 TLDFEEVKEYSIVLEARDGGG--MIAQCTVEVEVIDENDNAPEVIFQSLPNLIMEDAEL- 360
Query: 551 GERVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFKV 609
G +A + D DS N E+ L+ V I ++ ++ + VLDREQ Y V
Sbjct: 361 GTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITV 420
Query: 610 NAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKG 669
A D+G P L S+++ + + D NDN P F Q + +V EN P + + V D D G
Sbjct: 421 TATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVRASDPDLG 480
Query: 670 RNAEMSLYI-------EENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPR 722
N ++S I E ++ SI ++G +++ +FD E + ++A D G P
Sbjct: 481 PNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQARDQGSPAL 540
Query: 723 SATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGINA 777
SA ++ + V D NDNAP V P + + ++P ++ +V V+A D+D G NA
Sbjct: 541 SANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVTKVVAVDADSGHNA 600
Query: 778 DLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837
L+Y ++ + LF + +G V L + RL+V V D GQP S T +H+
Sbjct: 601 WLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLSATATLHL 660
Query: 838 FVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILI 897
+S+ + DI P + L + V +++V+ ++ +
Sbjct: 661 VFADSLQE---------------VLPDITDRPDPSDLQAELQFYLVVALALISVLFLVAM 705
Query: 898 VV 899
++
Sbjct: 706 IL 707
Score = 110 bits (274), Expect = 9e-24
Identities = 77/274 (28%), Positives = 134/274 (48%), Gaps = 19/274 (6%)
Query: 576 SSVMGIFAIDPDSGDILVNTVLDREQ------TDRYEFKVNAKDKGIPVLQGSTTVIVQV 629
SS F + +SG++LV++ LDRE+ EF+ A++ V V++
Sbjct: 69 SSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENP-----LNFYHVNVEI 123
Query: 630 ADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIFSI 687
D ND+ PKF Q+ F + E+ QP + + + DAD G N + + ++ ++ +
Sbjct: 124 EDINDHTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINK 183
Query: 688 ENDTGTIYSTM----SFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVT 743
E G+ Y M DRE Q +Y + A+D G PP S+TA + + V D NDNAP +
Sbjct: 184 EKSDGSKYPEMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFS 243
Query: 744 LPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSL 803
+++ L + T V V ATD D+G+NA++ +S + F+++ +G +++
Sbjct: 244 --QDVYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEITV 301
Query: 804 VGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837
+ L + + +V++ D G T V V
Sbjct: 302 LNTLDFEEVKEYSIVLEARDGGGMIAQCTVEVEV 335
>gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precursor
[Homo sapiens]
Length = 923
Score = 336 bits (861), Expect = 8e-92
Identities = 230/731 (31%), Positives = 349/731 (47%), Gaps = 101/731 (13%)
Query: 20 LLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYLKID 78
L LSL A + +RYR+ EE P +GN+A+DLG V + S Y +
Sbjct: 19 LFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVS 78
Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDIND 138
+GEL S R +DRE++ + C L+FE P ++ + V + DIND
Sbjct: 79 AESGELLVSSR-LDREEI-----CGKKPACALEFEAVAENP----LNFYHVNVEIEDIND 128
Query: 139 NTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRA 198
+TP F L + E+ GT ++L +A D D G N ++ Y+L
Sbjct: 129 HTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQL---------------- 172
Query: 199 GAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQP 258
+P S+ + +D G K P
Sbjct: 173 -------------------------------------SPSDHFSLINKEKSD---GSKYP 192
Query: 259 QLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLA 318
++++K LDRE++ SY LTL D G PP SS A + VL+TD NDN+P F + VY L+
Sbjct: 193 EMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDVYRVSLS 252
Query: 319 ENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEV 378
EN PGT +LQ+ A D D GVN +I + F A++ + L+ +G ++VL+ +D EEV
Sbjct: 253 ENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQ--FDLNSNTGEITVLNTLDFEEV 310
Query: 379 NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLV 438
+ + ARD G + TV + + DENDN P + + + + + ED +
Sbjct: 311 KEYSIVLEARDGG--GMIAQCTVEVEVIDENDNAPEVIFQSLPNL--------IMEDAEL 360
Query: 439 DTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEAT 498
T IAL++V D+D NG VTC + GDVPF++ +S + Y L T LD E
Sbjct: 361 GTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSS-------RNTYKLVTDAVLDREQN 413
Query: 499 REFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVL 558
E+N+ + A D G P LSS++S+ + +GD NDN P+F QS V+ ENN PG ++ V
Sbjct: 414 PEYNITVTATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVR 473
Query: 559 ATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAK 612
A+D D G N +++Y + +S + +I +SG + D EQ +E + A+
Sbjct: 474 ASDPDLGPNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQAR 533
Query: 613 DKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNSPVGMVTVMD 665
D+G P L + ++ V V D+NDN P+ + V +P V V +D
Sbjct: 534 DQGSPALSANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVTKVVAVD 593
Query: 666 ADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRS 723
AD G NA +S ++ + + +FS+ TG + + + V DGG PP S
Sbjct: 594 ADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLS 653
Query: 724 ATATVSLFVMD 734
ATAT+ L D
Sbjct: 654 ATATLHLVFAD 664
Score = 228 bits (582), Expect = 2e-59
Identities = 175/662 (26%), Positives = 305/662 (46%), Gaps = 58/662 (8%)
Query: 259 QLIVKGALDREQRDSYE--LTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEAD 316
+L+V LDRE+ + L + P + + V I D+ND++P+F ++ +E
Sbjct: 83 ELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHV-NVEIEDINDHTPKFTQNSFELQ 141
Query: 317 LAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW----LSVLHR 372
++E++ PGT + A D D+G N Y + L+ +++ G + +
Sbjct: 142 ISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHF--SLINKEKSDGSKYPEMVLKTP 199
Query: 373 IDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANV 432
+DRE+ T+ A D G PP + A + + + D NDN P + + R+ L
Sbjct: 200 LDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFS-QDVYRVSL------- 251
Query: 433 AEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASD-TEGDQNKKKYFLHTST 491
+E+V T + V +D+D+G N +T F AS T+ D N +
Sbjct: 252 SENVYPGTTVLQVTATDQDEGVNAEIT--------FSFSEASQITQFDLNSNTGEITVLN 303
Query: 492 PLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPP-MFGQSVVEVYFPENNIP 550
LD+E +E+++V+ A D G + + ++ V+V D NDN P + QS+ + + +
Sbjct: 304 TLDFEEVKEYSIVLEARDGGG--MIAQCTVEVEVIDENDNAPEVIFQSLPNLIMEDAEL- 360
Query: 551 GERVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFKV 609
G +A + D DS N E+ L+ V I ++ ++ + VLDREQ Y V
Sbjct: 361 GTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITV 420
Query: 610 NAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKG 669
A D+G P L S+++ + + D NDN P F Q + +V EN P + + V D D G
Sbjct: 421 TATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVRASDPDLG 480
Query: 670 RNAEMSLYI-------EENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPR 722
N ++S I E ++ SI ++G +++ +FD E + ++A D G P
Sbjct: 481 PNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQARDQGSPAL 540
Query: 723 SATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGINA 777
SA ++ + V D NDNAP V P + + ++P ++ +V V+A D+D G NA
Sbjct: 541 SANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVTKVVAVDADSGHNA 600
Query: 778 DLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837
L+Y ++ + LF + +G V L + RL+V V D GQP S T +H+
Sbjct: 601 WLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLSATATLHL 660
Query: 838 FVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILI 897
+S+ + DI P + L + V +++V+ ++ +
Sbjct: 661 VFADSLQE---------------VLPDITDRPDPSDLQAELQFYLVVALALISVLFLVAM 705
Query: 898 VV 899
++
Sbjct: 706 IL 707
Score = 110 bits (274), Expect = 9e-24
Identities = 77/274 (28%), Positives = 134/274 (48%), Gaps = 19/274 (6%)
Query: 576 SSVMGIFAIDPDSGDILVNTVLDREQ------TDRYEFKVNAKDKGIPVLQGSTTVIVQV 629
SS F + +SG++LV++ LDRE+ EF+ A++ V V++
Sbjct: 69 SSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENP-----LNFYHVNVEI 123
Query: 630 ADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIFSI 687
D ND+ PKF Q+ F + E+ QP + + + DAD G N + + ++ ++ +
Sbjct: 124 EDINDHTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINK 183
Query: 688 ENDTGTIYSTM----SFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVT 743
E G+ Y M DRE Q +Y + A+D G PP S+TA + + V D NDNAP +
Sbjct: 184 EKSDGSKYPEMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFS 243
Query: 744 LPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSL 803
+++ L + T V V ATD D+G+NA++ +S + F+++ +G +++
Sbjct: 244 --QDVYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEITV 301
Query: 804 VGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837
+ L + + +V++ D G T V V
Sbjct: 302 LNTLDFEEVKEYSIVLEARDGGGMIAQCTVEVEV 335
>gi|14270508 protocadherin gamma subfamily B, 7 isoform 2 precursor
[Homo sapiens]
Length = 808
Score = 330 bits (845), Expect = 6e-90
Identities = 229/734 (31%), Positives = 344/734 (46%), Gaps = 105/734 (14%)
Query: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVT---GSGEVTFSLESGSEYL 75
LLLPL + +RY + EE +GN+A DLG+ + E+ S E +
Sbjct: 20 LLLPLFYPTLC--EPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARELRVSAEK--LHF 75
Query: 76 KIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLD 135
+D +G+L +R IDRE++ C+ + C L E V P +++F V++ D
Sbjct: 76 SVDAQSGDLLVKDR-IDREQI--CK---ERRRCELQLEAVVENP----LNIFHVIVVIED 125
Query: 136 INDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGES 195
+ND+ P F + L + E+ +G +L +A D D N +
Sbjct: 126 VNDHAPQFRKDEINLEISESVSLGMGTILESAEDPDISMNSL------------------ 167
Query: 196 RRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGE 255
SK +L +E F L D PDG
Sbjct: 168 --------------------------SKYQLSPNE------------YFSLVEKDNPDGG 189
Query: 256 KQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEA 315
K P+L+++ LDRE + ++ L L DGGDPPRS A +R+L+ D NDN P F + VY
Sbjct: 190 KYPELVLQKTLDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRV 249
Query: 316 DLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDR 375
L E+ PGT IL+++A D D G+N +I Y F + + + LD T+G + +D
Sbjct: 250 SLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQQPLDF 309
Query: 376 EEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAED 435
EEV + + A+DRG + + V++ + DENDN P I I + ++D V
Sbjct: 310 EEVERYTINIEAKDRGS--LSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPGVV-- 365
Query: 436 VLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDY 495
+AL + D+D GENG V C++ VPF++ +S+ Y L T LD
Sbjct: 366 ------VALFKTRDQDSGENGEVRCSLSRGVPFKIHSSSN-------NYYKLVTDEALDR 412
Query: 496 EATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVA 555
E T E+NV I A D G P LSS+ ++ + + D NDN P+FGQS V+ PENN PG +A
Sbjct: 413 EQTPEYNVTIAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASIA 472
Query: 556 TVLATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRYEFKV 609
V A+D D G N ++YSL +S + ++ SG + D EQ +E +
Sbjct: 473 QVSASDPDFGLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTL 532
Query: 610 NAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNSPVGMVT 662
A+D+G P L + ++ V V D+NDN P+ + V QP V V
Sbjct: 533 QARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDTVPRAAQPGYLVTKVV 592
Query: 663 VMDADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720
+DAD G NA +S ++ + + +FS+ TG + + + V DGG P
Sbjct: 593 AVDADSGHNAWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAVRDGGQP 652
Query: 721 PRSATATVSLFVMD 734
P SATAT+ L D
Sbjct: 653 PLSATATLHLVFAD 666
Score = 241 bits (616), Expect = 2e-63
Identities = 194/679 (28%), Positives = 316/679 (46%), Gaps = 61/679 (8%)
Query: 260 LIVKGALDREQ--RDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317
L+VK +DREQ ++ L++ + P + ++ V+I DVND++P+F K ++
Sbjct: 84 LLVKDRIDREQICKERRRCELQLEAVVENPLNIFHVI-VVIEDVNDHAPQFRKDEINLEI 142
Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW----LSVLHRI 373
+E+ + G + A D D+ +N +Y + L+ D G L + +
Sbjct: 143 SESVSLGMGTILESAEDPDISMNSLSKYQL--SPNEYFSLVEKDNPDGGKYPELVLQKTL 200
Query: 374 DREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVA 433
DRE + + A D G PP++ A + + + D NDN P + + + R+ L+
Sbjct: 201 DRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDN-PPVFSQDVYRVSLR------- 252
Query: 434 EDVLVDTPIALVQVSDRDQGENGVVTCTVVG--DVPFQLKPASDTEGDQNKKKYFLHTST 491
EDV T I V+ +D+D+G N +T + G D + T G+ + T
Sbjct: 253 EDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGN-------ILTQQ 305
Query: 492 PLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPG 551
PLD+E + + I A D GS LS+ +IV+V D NDN P + + E++ PG
Sbjct: 306 PLDFEEVERYTINIEAKDRGS--LSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPG 363
Query: 552 ERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGD---ILVNTVLDREQTDRYEFK 608
VA D DSG+N E+ SL V F I S + ++ + LDREQT Y
Sbjct: 364 VVVALFKTRDQDSGENGEVRCSLSRGVP--FKIHSSSNNYYKLVTDEALDREQTPEYNVT 421
Query: 609 VNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADK 668
+ A D+G P L S T+ + + D NDN P F Q + +V EN QP + + V+ D D
Sbjct: 422 IAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASIAQVSASDPDF 481
Query: 669 GRNAEMSLYIEENN-------NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPP 721
G N +S + ++ + S+ +G +++ +FD E T+ ++A D G P
Sbjct: 482 GLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPA 541
Query: 722 RSATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGIN 776
SA ++ + V D NDNAP V P + + +P ++ +V V+A D+D G N
Sbjct: 542 LSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDTVPRAAQPGYLVTKVVAVDADSGHN 601
Query: 777 ADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVH 836
A L+Y +V + LF + +G V +V L K RL+V V D GQP S T +H
Sbjct: 602 AWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAVRDGGQPPLSATATLH 661
Query: 837 VFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIIL 896
+ +S+ + D + P+ S+ + + VVA + +L +L
Sbjct: 662 LVFADSLQE---------------VLPDFSDHPTPSDSQAEMQFYL-VVALALISVLFLL 705
Query: 897 IVVMARYCRSKNKNGYEAG 915
V++A R + AG
Sbjct: 706 AVILAIALRLRQSFSPTAG 724
Score = 186 bits (471), Expect = 1e-46
Identities = 139/501 (27%), Positives = 221/501 (44%), Gaps = 26/501 (5%)
Query: 360 LDETSGWLSVLHRIDREEV-NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIR 418
+D SG L V RIDRE++ + R + + + V++ I+D ND+ P
Sbjct: 77 VDAQSGDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKD 136
Query: 419 KIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEG 478
+I ++E V + L D D N + + + F L + +G
Sbjct: 137 EIN--------LEISESVSLGMGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDG 188
Query: 479 DQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQS 538
+ + T LD E ++V+ A+D G P S + + V D NDNPP+F Q
Sbjct: 189 GKYPELVLQKT---LDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQD 245
Query: 539 VVEVYFPENNIPGERVATVLATDADSGKNAEIAYS---LDSSVMGIFAIDPDSGDILVNT 595
V V E+ PG + V ATD D G N+EI YS + +F++D +G+IL
Sbjct: 246 VYRVSLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQQ 305
Query: 596 VLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPN 655
LD E+ +RY + AKD+G L VIV+V D+NDN P+ + + + E+ P
Sbjct: 306 PLDFEEVERYTINIEAKDRG--SLSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPG 363
Query: 656 SPVGMVTVMDADKGRNAEMSLYIEEN--NNIFSIENDTGTIYSTMSFDREHQTTYTFRVK 713
V + D D G N E+ + I S N+ + + + DRE Y +
Sbjct: 364 VVVALFKTRDQDSGENGEVRCSLSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIA 423
Query: 714 AVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDD 773
A D G PP S++ T++L + D NDNAP ++ +P ++ +A V A+D D
Sbjct: 424 ATDRGKPPLSSSKTITLHITDVNDNAP--VFGQSAYLVHVPENNQPGASIAQVSASDPDF 481
Query: 774 GINADLNYSIVGGN-----PFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPS 828
G+N ++YS++ + + SGVV + L +Q D G P+
Sbjct: 482 GLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPA 541
Query: 829 QSTTTLVHVFVNESVSNATAI 849
S + V V + NA +
Sbjct: 542 LSANVSLRVLVGDRNDNAPRV 562
Score = 103 bits (257), Expect = 9e-22
Identities = 80/273 (29%), Positives = 133/273 (48%), Gaps = 27/273 (9%)
Query: 582 FAIDPDSGDILVNTVLDREQ----TDRYEFKVNA-KDKGIPVLQGSTTVIVQVADKNDND 636
F++D SGD+LV +DREQ R E ++ A + + + VIV + D ND+
Sbjct: 75 FSVDAQSGDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFH----VIVVIEDVNDHA 130
Query: 637 PKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEM---SLYIEENNNIFSI---END 690
P+F +D + E++ +GM T++++ + + M S Y N FS+ +N
Sbjct: 131 PQFRKDEINLEISESVS----LGMGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNP 186
Query: 691 TGTIYSTM----SFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPK 746
G Y + + DRE Q+ + + A+DGGDPPRS TA + + V+D NDN P + +
Sbjct: 187 DGGKYPELVLQKTLDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFS--Q 244
Query: 747 NISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVG--GNPFKLFEIDPTSGVVSLV 804
++ L T + V ATD D+GIN+++ YS G +F +D T+G +
Sbjct: 245 DVYRVSLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQ 304
Query: 805 GKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837
L + + + ++ D G S +V V
Sbjct: 305 QPLDFEEVERYTINIEAKDRGSLSTRCKVIVEV 337
>gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precursor
[Homo sapiens]
Length = 929
Score = 330 bits (845), Expect = 6e-90
Identities = 229/734 (31%), Positives = 344/734 (46%), Gaps = 105/734 (14%)
Query: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVT---GSGEVTFSLESGSEYL 75
LLLPL + +RY + EE +GN+A DLG+ + E+ S E +
Sbjct: 20 LLLPLFYPTLC--EPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARELRVSAEK--LHF 75
Query: 76 KIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLD 135
+D +G+L +R IDRE++ C+ + C L E V P +++F V++ D
Sbjct: 76 SVDAQSGDLLVKDR-IDREQI--CK---ERRRCELQLEAVVENP----LNIFHVIVVIED 125
Query: 136 INDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGES 195
+ND+ P F + L + E+ +G +L +A D D N +
Sbjct: 126 VNDHAPQFRKDEINLEISESVSLGMGTILESAEDPDISMNSL------------------ 167
Query: 196 RRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGE 255
SK +L +E F L D PDG
Sbjct: 168 --------------------------SKYQLSPNE------------YFSLVEKDNPDGG 189
Query: 256 KQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEA 315
K P+L+++ LDRE + ++ L L DGGDPPRS A +R+L+ D NDN P F + VY
Sbjct: 190 KYPELVLQKTLDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRV 249
Query: 316 DLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDR 375
L E+ PGT IL+++A D D G+N +I Y F + + + LD T+G + +D
Sbjct: 250 SLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQQPLDF 309
Query: 376 EEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAED 435
EEV + + A+DRG + + V++ + DENDN P I I + ++D V
Sbjct: 310 EEVERYTINIEAKDRGS--LSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPGVV-- 365
Query: 436 VLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDY 495
+AL + D+D GENG V C++ VPF++ +S+ Y L T LD
Sbjct: 366 ------VALFKTRDQDSGENGEVRCSLSRGVPFKIHSSSN-------NYYKLVTDEALDR 412
Query: 496 EATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVA 555
E T E+NV I A D G P LSS+ ++ + + D NDN P+FGQS V+ PENN PG +A
Sbjct: 413 EQTPEYNVTIAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASIA 472
Query: 556 TVLATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRYEFKV 609
V A+D D G N ++YSL +S + ++ SG + D EQ +E +
Sbjct: 473 QVSASDPDFGLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTL 532
Query: 610 NAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNSPVGMVT 662
A+D+G P L + ++ V V D+NDN P+ + V QP V V
Sbjct: 533 QARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDTVPRAAQPGYLVTKVV 592
Query: 663 VMDADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720
+DAD G NA +S ++ + + +FS+ TG + + + V DGG P
Sbjct: 593 AVDADSGHNAWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAVRDGGQP 652
Query: 721 PRSATATVSLFVMD 734
P SATAT+ L D
Sbjct: 653 PLSATATLHLVFAD 666
Score = 241 bits (616), Expect = 2e-63
Identities = 194/679 (28%), Positives = 316/679 (46%), Gaps = 61/679 (8%)
Query: 260 LIVKGALDREQ--RDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317
L+VK +DREQ ++ L++ + P + ++ V+I DVND++P+F K ++
Sbjct: 84 LLVKDRIDREQICKERRRCELQLEAVVENPLNIFHVI-VVIEDVNDHAPQFRKDEINLEI 142
Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW----LSVLHRI 373
+E+ + G + A D D+ +N +Y + L+ D G L + +
Sbjct: 143 SESVSLGMGTILESAEDPDISMNSLSKYQL--SPNEYFSLVEKDNPDGGKYPELVLQKTL 200
Query: 374 DREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVA 433
DRE + + A D G PP++ A + + + D NDN P + + + R+ L+
Sbjct: 201 DRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDN-PPVFSQDVYRVSLR------- 252
Query: 434 EDVLVDTPIALVQVSDRDQGENGVVTCTVVG--DVPFQLKPASDTEGDQNKKKYFLHTST 491
EDV T I V+ +D+D+G N +T + G D + T G+ + T
Sbjct: 253 EDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGN-------ILTQQ 305
Query: 492 PLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPG 551
PLD+E + + I A D GS LS+ +IV+V D NDN P + + E++ PG
Sbjct: 306 PLDFEEVERYTINIEAKDRGS--LSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPG 363
Query: 552 ERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGD---ILVNTVLDREQTDRYEFK 608
VA D DSG+N E+ SL V F I S + ++ + LDREQT Y
Sbjct: 364 VVVALFKTRDQDSGENGEVRCSLSRGVP--FKIHSSSNNYYKLVTDEALDREQTPEYNVT 421
Query: 609 VNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADK 668
+ A D+G P L S T+ + + D NDN P F Q + +V EN QP + + V+ D D
Sbjct: 422 IAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASIAQVSASDPDF 481
Query: 669 GRNAEMSLYIEENN-------NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPP 721
G N +S + ++ + S+ +G +++ +FD E T+ ++A D G P
Sbjct: 482 GLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPA 541
Query: 722 RSATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGIN 776
SA ++ + V D NDNAP V P + + +P ++ +V V+A D+D G N
Sbjct: 542 LSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDTVPRAAQPGYLVTKVVAVDADSGHN 601
Query: 777 ADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVH 836
A L+Y +V + LF + +G V +V L K RL+V V D GQP S T +H
Sbjct: 602 AWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAVRDGGQPPLSATATLH 661
Query: 837 VFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIIL 896
+ +S+ + D + P+ S+ + + VVA + +L +L
Sbjct: 662 LVFADSLQE---------------VLPDFSDHPTPSDSQAEMQFYL-VVALALISVLFLL 705
Query: 897 IVVMARYCRSKNKNGYEAG 915
V++A R + AG
Sbjct: 706 AVILAIALRLRQSFSPTAG 724
Score = 186 bits (471), Expect = 1e-46
Identities = 139/501 (27%), Positives = 221/501 (44%), Gaps = 26/501 (5%)
Query: 360 LDETSGWLSVLHRIDREEV-NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIR 418
+D SG L V RIDRE++ + R + + + V++ I+D ND+ P
Sbjct: 77 VDAQSGDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKD 136
Query: 419 KIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEG 478
+I ++E V + L D D N + + + F L + +G
Sbjct: 137 EIN--------LEISESVSLGMGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDG 188
Query: 479 DQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQS 538
+ + T LD E ++V+ A+D G P S + + V D NDNPP+F Q
Sbjct: 189 GKYPELVLQKT---LDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQD 245
Query: 539 VVEVYFPENNIPGERVATVLATDADSGKNAEIAYS---LDSSVMGIFAIDPDSGDILVNT 595
V V E+ PG + V ATD D G N+EI YS + +F++D +G+IL
Sbjct: 246 VYRVSLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQQ 305
Query: 596 VLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPN 655
LD E+ +RY + AKD+G L VIV+V D+NDN P+ + + + E+ P
Sbjct: 306 PLDFEEVERYTINIEAKDRG--SLSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPG 363
Query: 656 SPVGMVTVMDADKGRNAEMSLYIEEN--NNIFSIENDTGTIYSTMSFDREHQTTYTFRVK 713
V + D D G N E+ + I S N+ + + + DRE Y +
Sbjct: 364 VVVALFKTRDQDSGENGEVRCSLSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIA 423
Query: 714 AVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDD 773
A D G PP S++ T++L + D NDNAP ++ +P ++ +A V A+D D
Sbjct: 424 ATDRGKPPLSSSKTITLHITDVNDNAP--VFGQSAYLVHVPENNQPGASIAQVSASDPDF 481
Query: 774 GINADLNYSIVGGN-----PFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPS 828
G+N ++YS++ + + SGVV + L +Q D G P+
Sbjct: 482 GLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPA 541
Query: 829 QSTTTLVHVFVNESVSNATAI 849
S + V V + NA +
Sbjct: 542 LSANVSLRVLVGDRNDNAPRV 562
Score = 103 bits (257), Expect = 9e-22
Identities = 80/273 (29%), Positives = 133/273 (48%), Gaps = 27/273 (9%)
Query: 582 FAIDPDSGDILVNTVLDREQ----TDRYEFKVNA-KDKGIPVLQGSTTVIVQVADKNDND 636
F++D SGD+LV +DREQ R E ++ A + + + VIV + D ND+
Sbjct: 75 FSVDAQSGDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFH----VIVVIEDVNDHA 130
Query: 637 PKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEM---SLYIEENNNIFSI---END 690
P+F +D + E++ +GM T++++ + + M S Y N FS+ +N
Sbjct: 131 PQFRKDEINLEISESVS----LGMGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNP 186
Query: 691 TGTIYSTM----SFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPK 746
G Y + + DRE Q+ + + A+DGGDPPRS TA + + V+D NDN P + +
Sbjct: 187 DGGKYPELVLQKTLDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFS--Q 244
Query: 747 NISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVG--GNPFKLFEIDPTSGVVSLV 804
++ L T + V ATD D+GIN+++ YS G +F +D T+G +
Sbjct: 245 DVYRVSLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQ 304
Query: 805 GKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837
L + + + ++ D G S +V V
Sbjct: 305 QPLDFEEVERYTINIEAKDRGSLSTRCKVIVEV 337
>gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precursor
[Homo sapiens]
Length = 878
Score = 322 bits (825), Expect = 1e-87
Identities = 234/758 (30%), Positives = 348/758 (45%), Gaps = 106/758 (13%)
Query: 34 LRYRLAEEGPADVRIGNVASDLGIVTG---SGEVTFSLESGSEYLKIDNLTGELSTSERR 90
LRY + EE +GNVA DLG+ S + E Y + ++G L+ +++
Sbjct: 31 LRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQK- 89
Query: 91 IDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTL 150
IDRE L C L +V P ++L +V +LD+NDN+P+F +P +
Sbjct: 90 IDRESLCGAS-----TSCLLPVQVVTEHP----LELIRVEVEILDLNDNSPSFATPEREM 140
Query: 151 TVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGGG 210
+ E+ G + L DSA P G
Sbjct: 141 RISESAASGARFPL-------------------------------------DSAQDPDVG 163
Query: 211 GNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQ 270
N S +S F L V DG+ P+L+++ LDRE
Sbjct: 164 TNTVS-------------------FYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREA 204
Query: 271 RDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQL 330
+ ++L L DGG P RS ++ V++ D+NDN+P F+ SV + EN+ GT +L+L
Sbjct: 205 QARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRL 264
Query: 331 RAADLDVGVNGQIEYVFGAAT-ESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARD 389
A D D G NGQ++Y FG T E+VR L LD +SG + VL ID EE ARD
Sbjct: 265 NATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARD 324
Query: 390 RGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSD 449
+GQP + +++ D NDN P + + + V E V T + L V D
Sbjct: 325 QGQPAMEGHCVIQVDVGDVNDNAPEVLLASLAN--------PVLESTPVGTVVGLFNVRD 376
Query: 450 RDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVD 509
RD G NG V+ + D+PFQ+KP ++ Y L TS PLD EAT + + ++A D
Sbjct: 377 RDSGRNGEVSLDISPDLPFQIKP--------SENHYSLLTSQPLDREATSHYIIELLASD 428
Query: 510 SGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAE 569
+GSPSL + ++ + + D NDN P F Q + Y EN PG + TV A+D D+G NA
Sbjct: 429 AGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNAR 488
Query: 570 IAYSL-DSSVMGIFA-----IDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGST 623
+ YS+ + V G A ++P+ G I D E + V +D G P L +T
Sbjct: 489 LTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANT 548
Query: 624 TVIVQVADKNDNDPKFM------QDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLY 677
++ V V D+NDN P + + + + P S V VT +DAD G NA +S
Sbjct: 549 SLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYS 608
Query: 678 IEENN---NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMD 734
+ + +F + TG + + + + T V D GDP S+TATV L + D
Sbjct: 609 LLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLED 668
Query: 735 ENDNAPTVTLPKNISYTLLPPS-SNVRTVVATVLATDS 771
E+ +PK+ + + PP S++ + LAT S
Sbjct: 669 EDPE----EMPKSSDFLIHPPERSDLTLYLIVALATVS 702
Score = 208 bits (529), Expect = 3e-53
Identities = 178/649 (27%), Positives = 290/649 (44%), Gaps = 67/649 (10%)
Query: 294 LRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATES 353
+ V I D+NDNSP F E ++E++A G A D DVG N Y +
Sbjct: 119 VEVEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHF 178
Query: 354 VRRLLRLDETSGW--LSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDN 411
+ L + + L + ++DRE + + + A D G P ++ + + + D NDN
Sbjct: 179 SLNVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDN 238
Query: 412 VPSIE--IRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVV-------TCTV 462
P+ + + ++G + E+ + T + + +D D+G NG + T
Sbjct: 239 APTFQSSVLRVG----------IPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEA 288
Query: 463 VGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLI 522
V ++ F L P+S +H P+D+E +R + + A D G P++ + +
Sbjct: 289 VRNL-FGLDPSSGA----------IHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQ 337
Query: 523 VKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIF 582
V VGD NDN P + + E+ G V D DSG+N E+ SLD S F
Sbjct: 338 VDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEV--SLDISPDLPF 395
Query: 583 AIDPDSG--DILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFM 640
I P +L + LDRE T Y ++ A D G P L T+ + ++D NDN P+F
Sbjct: 396 QIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFN 455
Query: 641 QDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEEN-------NNIFSIENDTGT 693
Q ++T Y+ EN P S + V D D G NA ++ I N ++ + + G
Sbjct: 456 QQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGR 515
Query: 694 IYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPK----NIS 749
I++ +FD E V D G PP A ++ +FV+DENDNAP V P+ + +
Sbjct: 516 IFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSA 575
Query: 750 YTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFK-LFEIDPTSGVVSLVGKLT 808
LP S+ ++V V A D+D G NA L+YS++ + LF + +G V L
Sbjct: 576 PQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALL 635
Query: 809 QKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGD 868
+ ++VV V D+G PS S+T V + + + +P + D
Sbjct: 636 EDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE------------EMPKSSDFLIH 683
Query: 869 PSYEISKQRLSIVIGVVAGIMTVILIILI--VVMARYCRSKNKNGYEAG 915
P +R + + ++ + TV L+ L+ ++ C N +G G
Sbjct: 684 P-----PERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADGDGGG 727
Score = 102 bits (253), Expect = 3e-21
Identities = 79/286 (27%), Positives = 129/286 (45%), Gaps = 28/286 (9%)
Query: 582 FAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTT-------VIVQVADKND 634
F++ SG + VN +DRE A + +Q T V V++ D ND
Sbjct: 75 FSLSLMSGALAVNQKIDRESL------CGASTSCLLPVQVVTEHPLELIRVEVEILDLND 128
Query: 635 NDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDT--- 691
N P F + E+ + + + D D G N +S Y N+ FS+ T
Sbjct: 129 NSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNT-VSFYTLSPNSHFSLNVKTLKD 187
Query: 692 ----GTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKN 747
+ DRE Q + + AVDGG P RS T +S+ V+D NDNAPT +
Sbjct: 188 GKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPT--FQSS 245
Query: 748 ISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFK----LFEIDPTSGVVSL 803
+ +P ++ + T++ + ATD D+G N L+YS G + + LF +DP+SG + +
Sbjct: 246 VLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSF-GDHTSEAVRNLFGLDPSSGAIHV 304
Query: 804 VGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAI 849
+G + + + + + D GQP+ ++ V V + NA +
Sbjct: 305 LGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEV 350
Score = 48.9 bits (115), Expect = 3e-05
Identities = 56/221 (25%), Positives = 91/221 (41%), Gaps = 16/221 (7%)
Query: 646 FYVKENLQPNSPVGMVTV---MDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDR 702
+ V E +P + VG V + + + L EEN FS+ +G + DR
Sbjct: 33 YSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQKIDR 92
Query: 703 EH----QTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSN 758
E T+ V+ V + P V + ++D NDN+P+ P+ +S
Sbjct: 93 ESLCGASTSCLLPVQVVT--EHPLE-LIRVEVEILDLNDNSPSFATPEREMRISESAASG 149
Query: 759 VRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSG----VVSLVGKLTQKHYGL 814
R + + A D D G N Y++ + F L G + L +L ++
Sbjct: 150 ARFPLDS--AQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQAR 207
Query: 815 HRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIAR 855
H+LV+ D G P++S TTL+ V V + NA S + R
Sbjct: 208 HQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLR 248
>gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor
[Homo sapiens]
Length = 944
Score = 322 bits (825), Expect = 1e-87
Identities = 234/758 (30%), Positives = 348/758 (45%), Gaps = 106/758 (13%)
Query: 34 LRYRLAEEGPADVRIGNVASDLGIVTG---SGEVTFSLESGSEYLKIDNLTGELSTSERR 90
LRY + EE +GNVA DLG+ S + E Y + ++G L+ +++
Sbjct: 31 LRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQK- 89
Query: 91 IDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTL 150
IDRE L C L +V P ++L +V +LD+NDN+P+F +P +
Sbjct: 90 IDRESLCGAS-----TSCLLPVQVVTEHP----LELIRVEVEILDLNDNSPSFATPEREM 140
Query: 151 TVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGGG 210
+ E+ G + L DSA P G
Sbjct: 141 RISESAASGARFPL-------------------------------------DSAQDPDVG 163
Query: 211 GNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQ 270
N S +S F L V DG+ P+L+++ LDRE
Sbjct: 164 TNTVS-------------------FYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREA 204
Query: 271 RDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQL 330
+ ++L L DGG P RS ++ V++ D+NDN+P F+ SV + EN+ GT +L+L
Sbjct: 205 QARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRL 264
Query: 331 RAADLDVGVNGQIEYVFGAAT-ESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARD 389
A D D G NGQ++Y FG T E+VR L LD +SG + VL ID EE ARD
Sbjct: 265 NATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARD 324
Query: 390 RGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSD 449
+GQP + +++ D NDN P + + + V E V T + L V D
Sbjct: 325 QGQPAMEGHCVIQVDVGDVNDNAPEVLLASLAN--------PVLESTPVGTVVGLFNVRD 376
Query: 450 RDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVD 509
RD G NG V+ + D+PFQ+KP ++ Y L TS PLD EAT + + ++A D
Sbjct: 377 RDSGRNGEVSLDISPDLPFQIKP--------SENHYSLLTSQPLDREATSHYIIELLASD 428
Query: 510 SGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAE 569
+GSPSL + ++ + + D NDN P F Q + Y EN PG + TV A+D D+G NA
Sbjct: 429 AGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNAR 488
Query: 570 IAYSL-DSSVMGIFA-----IDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGST 623
+ YS+ + V G A ++P+ G I D E + V +D G P L +T
Sbjct: 489 LTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANT 548
Query: 624 TVIVQVADKNDNDPKFM------QDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLY 677
++ V V D+NDN P + + + + P S V VT +DAD G NA +S
Sbjct: 549 SLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYS 608
Query: 678 IEENN---NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMD 734
+ + +F + TG + + + + T V D GDP S+TATV L + D
Sbjct: 609 LLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLED 668
Query: 735 ENDNAPTVTLPKNISYTLLPPS-SNVRTVVATVLATDS 771
E+ +PK+ + + PP S++ + LAT S
Sbjct: 669 EDPE----EMPKSSDFLIHPPERSDLTLYLIVALATVS 702
Score = 208 bits (529), Expect = 3e-53
Identities = 178/649 (27%), Positives = 290/649 (44%), Gaps = 67/649 (10%)
Query: 294 LRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATES 353
+ V I D+NDNSP F E ++E++A G A D DVG N Y +
Sbjct: 119 VEVEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHF 178
Query: 354 VRRLLRLDETSGW--LSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDN 411
+ L + + L + ++DRE + + + A D G P ++ + + + D NDN
Sbjct: 179 SLNVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDN 238
Query: 412 VPSIE--IRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVV-------TCTV 462
P+ + + ++G + E+ + T + + +D D+G NG + T
Sbjct: 239 APTFQSSVLRVG----------IPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEA 288
Query: 463 VGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLI 522
V ++ F L P+S +H P+D+E +R + + A D G P++ + +
Sbjct: 289 VRNL-FGLDPSSGA----------IHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQ 337
Query: 523 VKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIF 582
V VGD NDN P + + E+ G V D DSG+N E+ SLD S F
Sbjct: 338 VDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEV--SLDISPDLPF 395
Query: 583 AIDPDSG--DILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFM 640
I P +L + LDRE T Y ++ A D G P L T+ + ++D NDN P+F
Sbjct: 396 QIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFN 455
Query: 641 QDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEEN-------NNIFSIENDTGT 693
Q ++T Y+ EN P S + V D D G NA ++ I N ++ + + G
Sbjct: 456 QQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGR 515
Query: 694 IYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPK----NIS 749
I++ +FD E V D G PP A ++ +FV+DENDNAP V P+ + +
Sbjct: 516 IFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSA 575
Query: 750 YTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFK-LFEIDPTSGVVSLVGKLT 808
LP S+ ++V V A D+D G NA L+YS++ + LF + +G V L
Sbjct: 576 PQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALL 635
Query: 809 QKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGD 868
+ ++VV V D+G PS S+T V + + + +P + D
Sbjct: 636 EDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE------------EMPKSSDFLIH 683
Query: 869 PSYEISKQRLSIVIGVVAGIMTVILIILI--VVMARYCRSKNKNGYEAG 915
P +R + + ++ + TV L+ L+ ++ C N +G G
Sbjct: 684 P-----PERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADGDGGG 727
Score = 102 bits (253), Expect = 3e-21
Identities = 79/286 (27%), Positives = 129/286 (45%), Gaps = 28/286 (9%)
Query: 582 FAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTT-------VIVQVADKND 634
F++ SG + VN +DRE A + +Q T V V++ D ND
Sbjct: 75 FSLSLMSGALAVNQKIDRESL------CGASTSCLLPVQVVTEHPLELIRVEVEILDLND 128
Query: 635 NDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDT--- 691
N P F + E+ + + + D D G N +S Y N+ FS+ T
Sbjct: 129 NSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNT-VSFYTLSPNSHFSLNVKTLKD 187
Query: 692 ----GTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKN 747
+ DRE Q + + AVDGG P RS T +S+ V+D NDNAPT +
Sbjct: 188 GKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPT--FQSS 245
Query: 748 ISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFK----LFEIDPTSGVVSL 803
+ +P ++ + T++ + ATD D+G N L+YS G + + LF +DP+SG + +
Sbjct: 246 VLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSF-GDHTSEAVRNLFGLDPSSGAIHV 304
Query: 804 VGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAI 849
+G + + + + + D GQP+ ++ V V + NA +
Sbjct: 305 LGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEV 350
Score = 48.9 bits (115), Expect = 3e-05
Identities = 56/221 (25%), Positives = 91/221 (41%), Gaps = 16/221 (7%)
Query: 646 FYVKENLQPNSPVGMVTV---MDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDR 702
+ V E +P + VG V + + + L EEN FS+ +G + DR
Sbjct: 33 YSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQKIDR 92
Query: 703 EH----QTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSN 758
E T+ V+ V + P V + ++D NDN+P+ P+ +S
Sbjct: 93 ESLCGASTSCLLPVQVVT--EHPLE-LIRVEVEILDLNDNSPSFATPEREMRISESAASG 149
Query: 759 VRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSG----VVSLVGKLTQKHYGL 814
R + + A D D G N Y++ + F L G + L +L ++
Sbjct: 150 ARFPLDS--AQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQAR 207
Query: 815 HRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIAR 855
H+LV+ D G P++S TTL+ V V + NA S + R
Sbjct: 208 HQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLR 248
>gi|11128029 protocadherin gamma subfamily B, 6 isoform 1 precursor
[Homo sapiens]
Length = 930
Score = 321 bits (823), Expect = 2e-87
Identities = 229/738 (31%), Positives = 343/738 (46%), Gaps = 109/738 (14%)
Query: 19 LLLPLSLSL--AAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYL 75
+L PL L L + +RY + EE +GN+A DLG+ V + + +
Sbjct: 16 VLFPLLLPLFYPTLSEPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARKLRVSAEKLHF 75
Query: 76 KIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLD 135
+D +G+L + RIDRE++ C+ + C L E V P +++F V++ D
Sbjct: 76 SVDAESGDLLV-KNRIDREQI--CK---ERRRCELQLEAVVENP----LNIFHVIVVIED 125
Query: 136 INDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGES 195
+ND+ P F + L + E+ GT L ATD D N I+ Y++
Sbjct: 126 VNDHAPQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKI------------- 172
Query: 196 RRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGE 255
+S PY F L V DG
Sbjct: 173 ------NSNPY-------------------------------------FSLMVRVNSDGG 189
Query: 256 KQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEA 315
K P+L ++ LDRE++ S+ L L DGGDPPRS+ A + + + D NDN P F + Y
Sbjct: 190 KYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYRI 249
Query: 316 DLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDR 375
L+EN PG+P+LQ+ A D D GVN +I Y F + +S + + LDE +G + D
Sbjct: 250 SLSENLPPGSPVLQVTATDQDEGVNAEINYYFRSTAQSTKHMFSLDEKTGMIKNNQSFDF 309
Query: 376 EEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAED 435
E+V + V A+D G + + V++ I DENDN P I I ++++
Sbjct: 310 EDVERYTMEVEAKDGG--GLSTQCKVIIEILDENDNSPEIII------------TSLSDQ 355
Query: 436 VLVDTP----IALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTST 491
+L ++P +AL + D D G NG V C + D+PF++ +S+ Y L T
Sbjct: 356 ILENSPPGMVVALFKTRDLDFGGNGEVRCNIETDIPFKIYSSSN-------NYYKLVTDG 408
Query: 492 PLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPG 551
LD E T E+NV IVA D G P LSS+ S+ + V D NDN P+F Q+ V+ ENN PG
Sbjct: 409 ALDREQTPEYNVTIVATDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPG 468
Query: 552 ERVATVLATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRY 605
+A V A+D D G N I+YS+ +S V ++ SG + D EQ +
Sbjct: 469 ASIAQVSASDPDLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAF 528
Query: 606 EFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNSPV 658
+ A+D G P L + ++ V V D+NDN P+ + F V + +P V
Sbjct: 529 ALTLQARDHGSPTLSANVSLRVLVGDRNDNAPRVLYPALGPDGSAFFDMVPRSAEPGYLV 588
Query: 659 GMVTVMDADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVD 716
V +DAD G NA +S ++ + + +FS+ TG + + + V D
Sbjct: 589 TKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRD 648
Query: 717 GGDPPRSATATVSLFVMD 734
GG PP SATAT+ L D
Sbjct: 649 GGQPPLSATATLHLVFAD 666
Score = 228 bits (581), Expect = 2e-59
Identities = 171/660 (25%), Positives = 310/660 (46%), Gaps = 54/660 (8%)
Query: 260 LIVKGALDREQ--RDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317
L+VK +DREQ ++ L++ + P + ++ V+I DVND++P+F+K ++
Sbjct: 84 LLVKNRIDREQICKERRRCELQLEAVVENPLNIFHVI-VVIEDVNDHAPQFDKKEIHLEI 142
Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW---LSVLHRID 374
E+++ GT + A D D+ +N +Y + ++R++ G LS+ +D
Sbjct: 143 FESASAGTRLSLDPATDPDININSIKDYKINS-NPYFSLMVRVNSDGGKYPELSLEKLLD 201
Query: 375 REEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAE 434
REE + A D G PP++ A + +++KD NDN P + R RI L +E
Sbjct: 202 REEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDN-PPVFSRDEYRISL-------SE 253
Query: 435 DVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEG--DQNKKKYFLHTSTP 492
++ +P+ V +D+D+G N + + A T+ ++K + +
Sbjct: 254 NLPPGSPVLQVTATDQDEGVNAEINY-------YFRSTAQSTKHMFSLDEKTGMIKNNQS 306
Query: 493 LDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGE 552
D+E + + + A D G LS+ +I+++ D NDN P + + EN+ PG
Sbjct: 307 FDFEDVERYTMEVEAKDGGG--LSTQCKVIIEILDENDNSPEIIITSLSDQILENSPPGM 364
Query: 553 RVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFKVNA 611
VA D D G N E+ ++++ + I++ + ++ + LDREQT Y + A
Sbjct: 365 VVALFKTRDLDFGGNGEVRCNIETDIPFKIYSSSNNYYKLVTDGALDREQTPEYNVTIVA 424
Query: 612 KDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRN 671
D+G P L S ++ + VAD NDN P F Q + +V EN P + + V+ D D G N
Sbjct: 425 TDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPGASIAQVSASDPDLGLN 484
Query: 672 AEMSLYIEENN-------NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSA 724
+S I ++ + S+ +G +++ +FD E + ++A D G P SA
Sbjct: 485 GHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGSPTLSA 544
Query: 725 TATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGINADL 779
++ + V D NDNAP V P + + ++P S+ +V V+A D+D G NA L
Sbjct: 545 NVSLRVLVGDRNDNAPRVLYPALGPDGSAFFDMVPRSAEPGYLVTKVVAVDADSGHNAWL 604
Query: 780 NYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFV 839
+Y ++ + LF + +G V L + RL+V V D GQP S T +H+
Sbjct: 605 SYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVF 664
Query: 840 NESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVV 899
+++ + D++ P + L + V +++V+ ++ +++
Sbjct: 665 ADNLQE---------------ILPDLSDRPVLSDPQAELQFYLVVALALISVLFLLAVIL 709
Score = 192 bits (489), Expect = 1e-48
Identities = 146/503 (29%), Positives = 230/503 (45%), Gaps = 30/503 (5%)
Query: 360 LDETSGWLSVLHRIDREEV-NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIR 418
+D SG L V +RIDRE++ + R + + + V++ I+D ND+ P + +
Sbjct: 77 VDAESGDLLVKNRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFDKK 136
Query: 419 KIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEG 478
+I + E T ++L +D D N + + + F L +++G
Sbjct: 137 EIH--------LEIFESASAGTRLSLDPATDPDININSIKDYKINSNPYFSLMVRVNSDG 188
Query: 479 DQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQS 538
+ + L LD E R ++++ A+D G P S+ + + V DTNDNPP+F +
Sbjct: 189 GKYPE---LSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRD 245
Query: 539 VVEVYFPENNIPGERVATVLATDADSGKNAEIAY---SLDSSVMGIFAIDPDSGDILVNT 595
+ EN PG V V ATD D G NAEI Y S S +F++D +G I N
Sbjct: 246 EYRISLSENLPPGSPVLQVTATDQDEGVNAEINYYFRSTAQSTKHMFSLDEKTGMIKNNQ 305
Query: 596 VLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPN 655
D E +RY +V AKD G L VI+++ D+NDN P+ + + + EN P
Sbjct: 306 SFDFEDVERYTMEVEAKDGG--GLSTQCKVIIEILDENDNSPEIIITSLSDQILENSPPG 363
Query: 656 SPVGMVTVMDADKGRNAEMSLYIEEN--NNIFSIENDTGTIYSTMSFDREHQTTYTFRVK 713
V + D D G N E+ IE + I+S N+ + + + DRE Y +
Sbjct: 364 MVVALFKTRDLDFGGNGEVRCNIETDIPFKIYSSSNNYYKLVTDGALDREQTPEYNVTIV 423
Query: 714 AVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTL--LPPSSNVRTVVATVLATDS 771
A D G PP S++ +++L+V D NDNAP + + PP ++ +A V A+D
Sbjct: 424 ATDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPGAS----IAQVSASDP 479
Query: 772 DDGINADLNYSIVGGNPFKL-----FEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQ 826
D G+N ++YSIV + L + SGVV + L +Q D G
Sbjct: 480 DLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGS 539
Query: 827 PSQSTTTLVHVFVNESVSNATAI 849
P+ S + V V + NA +
Sbjct: 540 PTLSANVSLRVLVGDRNDNAPRV 562
Score = 98.6 bits (244), Expect = 3e-20
Identities = 80/277 (28%), Positives = 131/277 (47%), Gaps = 35/277 (12%)
Query: 582 FAIDPDSGDILVNTVLDREQT----DRYEFKVNAK-DKGIPVLQGSTTVIVQVADKNDND 636
F++D +SGD+LV +DREQ R E ++ A + + + VIV + D ND+
Sbjct: 75 FSVDAESGDLLVKNRIDREQICKERRRCELQLEAVVENPLNIFH----VIVVIEDVNDHA 130
Query: 637 PKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIE---NDTGT 693
P+F + + E+ + + + D D N+ + Y +N FS+ N G
Sbjct: 131 PQFDKKEIHLEIFESASAGTRLSLDPATDPDININS-IKDYKINSNPYFSLMVRVNSDGG 189
Query: 694 IYSTMSF----DREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-------V 742
Y +S DRE Q +++ + A+DGGDPPRSATA + + V D NDN P +
Sbjct: 190 KYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYRI 249
Query: 743 TLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSI--VGGNPFKLFEIDPTSGV 800
+L +N LPP S V V ATD D+G+NA++NY + +F +D +G+
Sbjct: 250 SLSEN-----LPPGS----PVLQVTATDQDEGVNAEINYYFRSTAQSTKHMFSLDEKTGM 300
Query: 801 VSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837
+ + + + V+ D G S ++ +
Sbjct: 301 IKNNQSFDFEDVERYTMEVEAKDGGGLSTQCKVIIEI 337
>gi|14270502 protocadherin gamma subfamily B, 6 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 321 bits (823), Expect = 2e-87
Identities = 229/738 (31%), Positives = 343/738 (46%), Gaps = 109/738 (14%)
Query: 19 LLLPLSLSL--AAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYL 75
+L PL L L + +RY + EE +GN+A DLG+ V + + +
Sbjct: 16 VLFPLLLPLFYPTLSEPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARKLRVSAEKLHF 75
Query: 76 KIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLD 135
+D +G+L + RIDRE++ C+ + C L E V P +++F V++ D
Sbjct: 76 SVDAESGDLLV-KNRIDREQI--CK---ERRRCELQLEAVVENP----LNIFHVIVVIED 125
Query: 136 INDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGES 195
+ND+ P F + L + E+ GT L ATD D N I+ Y++
Sbjct: 126 VNDHAPQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKI------------- 172
Query: 196 RRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGE 255
+S PY F L V DG
Sbjct: 173 ------NSNPY-------------------------------------FSLMVRVNSDGG 189
Query: 256 KQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEA 315
K P+L ++ LDRE++ S+ L L DGGDPPRS+ A + + + D NDN P F + Y
Sbjct: 190 KYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYRI 249
Query: 316 DLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDR 375
L+EN PG+P+LQ+ A D D GVN +I Y F + +S + + LDE +G + D
Sbjct: 250 SLSENLPPGSPVLQVTATDQDEGVNAEINYYFRSTAQSTKHMFSLDEKTGMIKNNQSFDF 309
Query: 376 EEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAED 435
E+V + V A+D G + + V++ I DENDN P I I ++++
Sbjct: 310 EDVERYTMEVEAKDGG--GLSTQCKVIIEILDENDNSPEIII------------TSLSDQ 355
Query: 436 VLVDTP----IALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTST 491
+L ++P +AL + D D G NG V C + D+PF++ +S+ Y L T
Sbjct: 356 ILENSPPGMVVALFKTRDLDFGGNGEVRCNIETDIPFKIYSSSN-------NYYKLVTDG 408
Query: 492 PLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPG 551
LD E T E+NV IVA D G P LSS+ S+ + V D NDN P+F Q+ V+ ENN PG
Sbjct: 409 ALDREQTPEYNVTIVATDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPG 468
Query: 552 ERVATVLATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRY 605
+A V A+D D G N I+YS+ +S V ++ SG + D EQ +
Sbjct: 469 ASIAQVSASDPDLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAF 528
Query: 606 EFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNSPV 658
+ A+D G P L + ++ V V D+NDN P+ + F V + +P V
Sbjct: 529 ALTLQARDHGSPTLSANVSLRVLVGDRNDNAPRVLYPALGPDGSAFFDMVPRSAEPGYLV 588
Query: 659 GMVTVMDADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVD 716
V +DAD G NA +S ++ + + +FS+ TG + + + V D
Sbjct: 589 TKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRD 648
Query: 717 GGDPPRSATATVSLFVMD 734
GG PP SATAT+ L D
Sbjct: 649 GGQPPLSATATLHLVFAD 666
Score = 228 bits (581), Expect = 2e-59
Identities = 171/660 (25%), Positives = 310/660 (46%), Gaps = 54/660 (8%)
Query: 260 LIVKGALDREQ--RDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317
L+VK +DREQ ++ L++ + P + ++ V+I DVND++P+F+K ++
Sbjct: 84 LLVKNRIDREQICKERRRCELQLEAVVENPLNIFHVI-VVIEDVNDHAPQFDKKEIHLEI 142
Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW---LSVLHRID 374
E+++ GT + A D D+ +N +Y + ++R++ G LS+ +D
Sbjct: 143 FESASAGTRLSLDPATDPDININSIKDYKINS-NPYFSLMVRVNSDGGKYPELSLEKLLD 201
Query: 375 REEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAE 434
REE + A D G PP++ A + +++KD NDN P + R RI L +E
Sbjct: 202 REEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDN-PPVFSRDEYRISL-------SE 253
Query: 435 DVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEG--DQNKKKYFLHTSTP 492
++ +P+ V +D+D+G N + + A T+ ++K + +
Sbjct: 254 NLPPGSPVLQVTATDQDEGVNAEINY-------YFRSTAQSTKHMFSLDEKTGMIKNNQS 306
Query: 493 LDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGE 552
D+E + + + A D G LS+ +I+++ D NDN P + + EN+ PG
Sbjct: 307 FDFEDVERYTMEVEAKDGGG--LSTQCKVIIEILDENDNSPEIIITSLSDQILENSPPGM 364
Query: 553 RVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFKVNA 611
VA D D G N E+ ++++ + I++ + ++ + LDREQT Y + A
Sbjct: 365 VVALFKTRDLDFGGNGEVRCNIETDIPFKIYSSSNNYYKLVTDGALDREQTPEYNVTIVA 424
Query: 612 KDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRN 671
D+G P L S ++ + VAD NDN P F Q + +V EN P + + V+ D D G N
Sbjct: 425 TDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPGASIAQVSASDPDLGLN 484
Query: 672 AEMSLYIEENN-------NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSA 724
+S I ++ + S+ +G +++ +FD E + ++A D G P SA
Sbjct: 485 GHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGSPTLSA 544
Query: 725 TATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGINADL 779
++ + V D NDNAP V P + + ++P S+ +V V+A D+D G NA L
Sbjct: 545 NVSLRVLVGDRNDNAPRVLYPALGPDGSAFFDMVPRSAEPGYLVTKVVAVDADSGHNAWL 604
Query: 780 NYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFV 839
+Y ++ + LF + +G V L + RL+V V D GQP S T +H+
Sbjct: 605 SYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVF 664
Query: 840 NESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVV 899
+++ + D++ P + L + V +++V+ ++ +++
Sbjct: 665 ADNLQE---------------ILPDLSDRPVLSDPQAELQFYLVVALALISVLFLLAVIL 709
Score = 192 bits (489), Expect = 1e-48
Identities = 146/503 (29%), Positives = 230/503 (45%), Gaps = 30/503 (5%)
Query: 360 LDETSGWLSVLHRIDREEV-NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIR 418
+D SG L V +RIDRE++ + R + + + V++ I+D ND+ P + +
Sbjct: 77 VDAESGDLLVKNRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFDKK 136
Query: 419 KIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEG 478
+I + E T ++L +D D N + + + F L +++G
Sbjct: 137 EIH--------LEIFESASAGTRLSLDPATDPDININSIKDYKINSNPYFSLMVRVNSDG 188
Query: 479 DQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQS 538
+ + L LD E R ++++ A+D G P S+ + + V DTNDNPP+F +
Sbjct: 189 GKYPE---LSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRD 245
Query: 539 VVEVYFPENNIPGERVATVLATDADSGKNAEIAY---SLDSSVMGIFAIDPDSGDILVNT 595
+ EN PG V V ATD D G NAEI Y S S +F++D +G I N
Sbjct: 246 EYRISLSENLPPGSPVLQVTATDQDEGVNAEINYYFRSTAQSTKHMFSLDEKTGMIKNNQ 305
Query: 596 VLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPN 655
D E +RY +V AKD G L VI+++ D+NDN P+ + + + EN P
Sbjct: 306 SFDFEDVERYTMEVEAKDGG--GLSTQCKVIIEILDENDNSPEIIITSLSDQILENSPPG 363
Query: 656 SPVGMVTVMDADKGRNAEMSLYIEEN--NNIFSIENDTGTIYSTMSFDREHQTTYTFRVK 713
V + D D G N E+ IE + I+S N+ + + + DRE Y +
Sbjct: 364 MVVALFKTRDLDFGGNGEVRCNIETDIPFKIYSSSNNYYKLVTDGALDREQTPEYNVTIV 423
Query: 714 AVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTL--LPPSSNVRTVVATVLATDS 771
A D G PP S++ +++L+V D NDNAP + + PP ++ +A V A+D
Sbjct: 424 ATDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPGAS----IAQVSASDP 479
Query: 772 DDGINADLNYSIVGGNPFKL-----FEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQ 826
D G+N ++YSIV + L + SGVV + L +Q D G
Sbjct: 480 DLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGS 539
Query: 827 PSQSTTTLVHVFVNESVSNATAI 849
P+ S + V V + NA +
Sbjct: 540 PTLSANVSLRVLVGDRNDNAPRV 562
Score = 98.6 bits (244), Expect = 3e-20
Identities = 80/277 (28%), Positives = 131/277 (47%), Gaps = 35/277 (12%)
Query: 582 FAIDPDSGDILVNTVLDREQT----DRYEFKVNAK-DKGIPVLQGSTTVIVQVADKNDND 636
F++D +SGD+LV +DREQ R E ++ A + + + VIV + D ND+
Sbjct: 75 FSVDAESGDLLVKNRIDREQICKERRRCELQLEAVVENPLNIFH----VIVVIEDVNDHA 130
Query: 637 PKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIE---NDTGT 693
P+F + + E+ + + + D D N+ + Y +N FS+ N G
Sbjct: 131 PQFDKKEIHLEIFESASAGTRLSLDPATDPDININS-IKDYKINSNPYFSLMVRVNSDGG 189
Query: 694 IYSTMSF----DREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-------V 742
Y +S DRE Q +++ + A+DGGDPPRSATA + + V D NDN P +
Sbjct: 190 KYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYRI 249
Query: 743 TLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSI--VGGNPFKLFEIDPTSGV 800
+L +N LPP S V V ATD D+G+NA++NY + +F +D +G+
Sbjct: 250 SLSEN-----LPPGS----PVLQVTATDQDEGVNAEINYYFRSTAQSTKHMFSLDEKTGM 300
Query: 801 VSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837
+ + + + V+ D G S ++ +
Sbjct: 301 IKNNQSFDFEDVERYTMEVEAKDGGGLSTQCKVIIEI 337
>gi|16933557 dachsous 1 precursor [Homo sapiens]
Length = 3298
Score = 320 bits (819), Expect = 6e-87
Identities = 248/805 (30%), Positives = 371/805 (46%), Gaps = 98/805 (12%)
Query: 34 LRYRLAEEGPADVRIGNVASDLGIVTGSGEVTF-SLESGSEY---LKIDNLTGELSTSER 89
L ++ EE PA IG++++ L T + + F S + GS L ID +G + T+ R
Sbjct: 47 LDLQIDEEQPAGTLIGDISAGLPAGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTA-R 105
Query: 90 RIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLT 149
+DRE+ + + + + P + V++ V V DIND+ P FP
Sbjct: 106 VLDREQRDR-------------YRFTAVTPDGATVEV---TVRVADINDHAPAFPQARAA 149
Query: 150 LTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGG 209
L V E+ GT Y L A D D GR G + Y L
Sbjct: 150 LQVPEHTAFGTRYPLEPARDADAGRLGTQGYAL--------------------------- 182
Query: 210 GGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDRE 269
SG G+G F L+ PDG P+L+V G LDRE
Sbjct: 183 -----SGDGAG---------------------ETFRLETRPGPDGTPVPELVVTGELDRE 216
Query: 270 QRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQ 329
R Y L L DGG PPR +QA+L V + D+ND++P F +S Y A ++E+ APG+P+LQ
Sbjct: 217 NRSHYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQ 276
Query: 330 LRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARD 389
+ A+D D GVNG + Y +D +G L + +D E+ V ARD
Sbjct: 277 VFASDADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQARD 336
Query: 390 RGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSD 449
G P+ A V ++++D NDN PS+ + + DG V+E +A + VSD
Sbjct: 337 GGAHPELGSAFVTVHVRDANDNQPSMTVIFLS----ADGSPQVSEAAPPGQLVARISVSD 392
Query: 450 RDQGENGVVTCTVV-GDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAV 508
D G+ V ++ G+ F L Q+ Y + + LD E +N+ + A
Sbjct: 393 PDDGDFAHVNVSLEGGEGHFAL-------STQDSVIYLVCVARRLDREERDAYNLRVTAT 445
Query: 509 DSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVY-FPENNIPGERVATVLATDADSGKN 567
DSGSP L + + ++ V D NDN P F + + PE +PG V V A D D G N
Sbjct: 446 DSGSPPLRAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTN 505
Query: 568 AEIAYSL-DSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626
++ YSL + F+IDP SG I LD E + + V A D G+P L S TV
Sbjct: 506 GQVTYSLAPGAHTHWFSIDPTSGIITTAASLDYELEPQPQLIVVATDGGLPPLASSATVS 565
Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYI-----EEN 681
V + D NDN+P+F + + + E QP + VT DAD G +S +
Sbjct: 566 VALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSG 625
Query: 682 NNIFSIENDTGTIYSTMSFDREH-QTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAP 740
+ F I+ +G + +T + DR+ +++ F V AVDGG + V +F+ DENDN P
Sbjct: 626 SPPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGGG--LKSMVYVKVFLSDENDNPP 683
Query: 741 TVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGV 800
P+ + + + S T V + A D D G + L+Y I+ GN LF +D SG+
Sbjct: 684 QF-YPREYAAS-ISAQSPPGTAVLRLRAHDPDQGSHGRLSYHILAGNSPPLFTLDEQSGL 741
Query: 801 VSLVGKLTQKHYGLHRLVVQVNDSG 825
+++ L ++ + +L + D G
Sbjct: 742 LTVAWPLARRANSVVQLEIGAEDGG 766
Score = 250 bits (639), Expect = 4e-66
Identities = 252/870 (28%), Positives = 374/870 (42%), Gaps = 138/870 (15%)
Query: 41 EGPADVRIGNVASDLGI----VTGSGEVTFSLESGSE-YLKIDNLTGELSTSERRIDREK 95
E P DV G + L +G VT+ L +G+ ++ +GEL T+ +DRE+
Sbjct: 1863 EVPEDVPAGTLLLQLQAHDPDAGANGHVTYYLGAGTAGAFLLEPSSGELRTAAA-LDREQ 1921
Query: 96 LPQCQMIFDENECFLDFEVSVI-----GPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTL 150
P F VS + GP + V + + V D+ND+ PTFP+ L L
Sbjct: 1922 CPS-----------YTFSVSAVDGAAAGPLSTTVSV---TITVRDVNDHAPTFPTSPLRL 1967
Query: 151 TVEENRPVGTLYLLPTAT----DRDFGRNGIERYELLQEPGGGGS----GGESRRA---- 198
+ P + L AT DRD G N Y L P G + GE R A
Sbjct: 1968 RLPRPGPSFSTPTLALATLRAEDRDAGANASILYRLAGTPPPGTTVDSYTGEIRVARSPV 2027
Query: 199 --GAADSAPYP-----GGGGNGASG----GGSGGSKR-------------RLDASEG--- 231
G D + G A+G G G ++R R +A G
Sbjct: 2028 ALGPRDRVLFIVATDLGRPARSATGVIIVGLQGEAERGPRFPRASSEATIRENAPPGTPI 2087
Query: 232 -------GGGTN--------PGGRSSVFELQVADTPDGEKQPQLIVKGALDREQRDSYEL 276
GGTN G F +Q + + + LD E L
Sbjct: 2088 VSPRAVHAGGTNGPITYSILSGNEKGTFSIQPSTGAITVRSAE-----GLDFEVSPRLRL 2142
Query: 277 TLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLD 336
L+ GG + +L + + D NDN+PRF + Y A L E+ P+LQ+ A DLD
Sbjct: 2143 VLQAESGG---AFAFTVLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVEADDLD 2199
Query: 337 VGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKT 396
G GQI Y AA++ R L +D T+G ++ +DRE + R +MA DRG P
Sbjct: 2200 QGSGGQISYSL-AASQPARGLFHVDPTTGTITTTAILDREIWAETRLVLMATDRGSPALV 2258
Query: 397 DKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENG 456
AT+ + + D NDN P+I + V+ED L+ + IA V +D D G
Sbjct: 2259 GSATLTVMVIDTNDNRPTIP---------QPWELRVSEDALLGSEIAQVTGNDVDSGP-- 2307
Query: 457 VVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTST--PLDYEATREFNVVIVAVDSGSPS 514
V + + S + + +Y S PLD+E + + ++A D
Sbjct: 2308 ---------VLWYVLSPSGPQDPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHDGPHEG 2358
Query: 515 LSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSL 574
++ L V V D NDN P F QS+ +V E+ PG + +V ATD DSG N I+Y L
Sbjct: 2359 RAN---LTVLVEDVNDNAPAFSQSLYQVMLLEHTPPGSAILSVSATDRDSGANGHISYHL 2415
Query: 575 DSSVMGIFAIDPDSGDI--LVNTV-LDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVAD 631
S G F++DP++G + +V TV L + + + + A+D G P TV VQ+ D
Sbjct: 2416 ASPADG-FSVDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDHGAPGRAARATVHVQLQD 2474
Query: 632 KNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRN---AEMSLYIEENNNIFSIE 688
+ND+ P F + V E+L P S + + DAD R+ + S+ +F +E
Sbjct: 2475 QNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEATDADGSRSHAAVDYSIISGNWGRVFQLE 2534
Query: 689 --------------NDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMD 734
G + D E T Y V A D G PP+S+ V++ V+D
Sbjct: 2535 PRLAEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADRGQPPQSSVVPVTVTVLD 2594
Query: 735 ENDNAPTVTLPKNISYTL-LPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFE 793
NDN P T SY + +P + V + V A+D+D G + + +++ G+P LFE
Sbjct: 2595 VNDNPPVFT---RASYRVTVPEDTPVGAELLHVEASDADPGPHGLVRFTVSSGDPSGLFE 2651
Query: 794 IDPTSGVVSLVGKLTQKHYGLHRLVVQVND 823
+D +SG + L L + H+LVVQ D
Sbjct: 2652 LDESSGTLRLAHALDCETQARHQLVVQAAD 2681
Score = 242 bits (618), Expect = 1e-63
Identities = 214/741 (28%), Positives = 313/741 (42%), Gaps = 112/741 (15%)
Query: 75 LKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVL 134
L++D TG LS + R +DRE P ++ + + S+ +V V
Sbjct: 1486 LRLDARTGALS-APRGLDRETTPALLLLVEATD-------RPANASRRRAARVSARVFVT 1537
Query: 135 DINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGE 194
D NDN P F SP + + E++P G L A D D G Y L
Sbjct: 1538 DENDNAPVFASPS-RVRLPEDQPPGPAALHVVARDPDLGEAARVSYRL------------ 1584
Query: 195 SRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDG 254
+ GG G RL +S G
Sbjct: 1585 --------------------ASGGDGHF--RLHSSTGA---------------------- 1600
Query: 255 EKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYE 314
L V LDREQR + LT+ D G PPRS+ +L V + DVND +P F++ Y
Sbjct: 1601 -----LSVVRPLDREQRAEHVLTVVASDHGSPPRSATQVLTVSVADVNDEAPTFQQQEYS 1655
Query: 315 ADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRID 374
L EN+ PGT +L LRA D DVG NGQ+ Y G ++ES LD +G L+ L +D
Sbjct: 1656 VLLRENNPPGTSLLTLRATDPDVGANGQVTY-GGVSSES----FSLDPDTGVLTTLRALD 1710
Query: 375 REEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAE 434
REE ++ TV A+DRG PP+ TV + ++DEND+ P+ G A+++
Sbjct: 1711 REEQEEINLTVYAQDRGSPPQLTHVTVRVAVEDENDHAPTF------------GSAHLSL 1758
Query: 435 DV---LVDTPIALVQVSDRDQGENGVVTCTVVGDVP---FQLKPASDTEGDQNKKKYFLH 488
+V + +++ SD D G NG + ++ P F L AS G
Sbjct: 1759 EVPEGQDPQTLTMLRASDPDVGANGQLQYRILDGDPSGAFVLDLASGEFG---------- 1808
Query: 489 TSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENN 548
T PLD E F + I A D G P+LS+ L V V D ND+ P F V PE+
Sbjct: 1809 TMRPLDREVEPAFQLRIEARDGGQPALSATLLLTVTVLDANDHAPAFPVPAYSVEVPEDV 1868
Query: 549 IPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFK 608
G + + A D D+G N + Y L + G F ++P SG++ LDREQ Y F
Sbjct: 1869 PAGTLLLQLQAHDPDAGANGHVTYYLGAGTAGAFLLEPSSGELRTAAALDREQCPSYTFS 1928
Query: 609 VNAKD-KGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKEN----LQPNSPVGMVTV 663
V+A D L + +V + V D ND+ P F + P + +
Sbjct: 1929 VSAVDGAAAGPLSTTVSVTITVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTLALATLRA 1988
Query: 664 MDADKGRNAEMSLYIEENNNI-FSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPR 722
D D G NA + + ++++ TG I S + A D G P R
Sbjct: 1989 EDRDAGANASILYRLAGTPPPGTTVDSYTGEIRVARSPVALGPRDRVLFIVATDLGRPAR 2048
Query: 723 SATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYS 782
SAT + + + E + P P+ S + ++ T + + A + G N + YS
Sbjct: 2049 SATGVIIVGLQGEAERGP--RFPRASSEATIRENAPPGTPIVSPRAVHA-GGTNGPITYS 2105
Query: 783 IVGGNPFKLFEIDPTSGVVSL 803
I+ GN F I P++G +++
Sbjct: 2106 ILSGNEKGTFSIQPSTGAITV 2126
Score = 228 bits (582), Expect = 2e-59
Identities = 217/795 (27%), Positives = 328/795 (41%), Gaps = 100/795 (12%)
Query: 61 SGEVTFSLESGSE--YLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIG 118
+G+VT+SL G+ + ID +G ++T+ +D E PQ Q+I V+ G
Sbjct: 505 NGQVTYSLAPGAHTHWFSIDPTSGIITTAAS-LDYELEPQPQLIV----------VATDG 553
Query: 119 PSQSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIE 178
V + D+NDN P F ++ E GT +L TATD D G G+
Sbjct: 554 GLPPLASSATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLL 613
Query: 179 RYELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPG 238
Y L GA G SG R+DA G
Sbjct: 614 SYSL------------------------------GAGLGSSGSPPFRIDAHSG------- 636
Query: 239 GRSSVFELQVADTPDGEKQPQLIVKGALDREQR-DSYELTLRVRDGGDPPRSSQAILRVL 297
+ LDR+Q S++ T+ DGG S ++V
Sbjct: 637 --------------------DVCTTRTLDRDQGPSSFDFTVTAVDGGG--LKSMVYVKVF 674
Query: 298 ITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRL 357
++D NDN P+F Y A ++ S PGT +L+LRA D D G +G++ Y A L
Sbjct: 675 LSDENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHILAGNSPP--L 732
Query: 358 LRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEI 417
LDE SG L+V + R + ++ + A D G A V ++I P E
Sbjct: 733 FTLDEQSGLLTVAWPLARRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPTPPIFEQ 792
Query: 418 RKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTE 477
+ V +V EDV T + +VQ + G VT ++ G P L
Sbjct: 793 LQY--------VFSVPEDVAPGTSVGIVQAHN-PPGRLAPVTLSLSGGDPRGLFSLDAVS 843
Query: 478 GDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQ 537
G L T PLD E + V SG P + + V + D NDN P F
Sbjct: 844 G-------LLQTLRPLDRELLGPVLELEVRAGSGVPPAFAVARVRVLLDDVNDNSPAFPA 896
Query: 538 SVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVL 597
V P N PG + T+ A D DSG N+ + ++L + G F +DP +G + + L
Sbjct: 897 PEDTVLLPPNTAPGTPIYTLRALDPDSGVNSRVTFTLLAGGGGAFTVDPTTGHVRLMRPL 956
Query: 598 DREQTDRYEFKVNAKDKGIP--VLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPN 655
+E ++ A+D G P V+VQ P+F + +
Sbjct: 957 GPSGGPAHELELEARDGGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRVDLPSGTTAG 1016
Query: 656 SPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAV 715
+ V V D G L E ++ F +E +G ++ + DRE Q Y +V AV
Sbjct: 1017 TQVLQVQAQAPD-GGPITYHLAAEGASSPFGLEPQSGWLWVRAALDREAQELYILKVMAV 1075
Query: 716 DGGDP---PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSD 772
G ++ TATV + ++++N+++P L ++ ++ + + T V V ATD D
Sbjct: 1076 SGSKAELGQQTGTATVRVSILNQNEHSP--RLSEDPTFLAVAENQPPGTSVGRVFATDRD 1133
Query: 773 DGINADLNYSIVG-GNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQST 831
G N L YS+ K F I P +G V+ + L ++ ++L+VQV D G P +ST
Sbjct: 1134 SGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGGSPPRST 1193
Query: 832 TTLVHVFVNESVSNA 846
T VHV V + N+
Sbjct: 1194 TGTVHVAVLDLNDNS 1208
Score = 226 bits (576), Expect = 9e-59
Identities = 237/859 (27%), Positives = 362/859 (42%), Gaps = 122/859 (14%)
Query: 58 VTGSGEVTFSLESG--SEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVS 115
V +G++ + + G S +D +GE T R +DRE P Q+ + +
Sbjct: 1779 VGANGQLQYRILDGDPSGAFVLDLASGEFGTM-RPLDREVEPAFQLRIEARD-------- 1829
Query: 116 VIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRN 175
G + V VLD ND+ P FP P ++ V E+ P GTL L A D D G N
Sbjct: 1830 --GGQPALSATLLLTVTVLDANDHAPAFPVPAYSVEVPEDVPAGTLLLQLQAHDPDAGAN 1887
Query: 176 GIERYELLQEPGGG----GSGGESRRAGAADSAPYPG-----GGGNGASGGGSGGSKRRL 226
G Y L G S GE R A A D P +GA+ G +
Sbjct: 1888 GHVTYYLGAGTAGAFLLEPSSGELRTAAALDREQCPSYTFSVSAVDGAAAGPLSTTVSVT 1947
Query: 227 DASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQRD-------------- 272
P +S L++ P L + L E RD
Sbjct: 1948 ITVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTLAL-ATLRAEDRDAGANASILYRLAGT 2006
Query: 273 --------SYELTLRVR------------------DGGDPPRSSQAILRVLITDVNDNSP 306
SY +RV D G P RS+ ++ V + + P
Sbjct: 2007 PPPGTTVDSYTGEIRVARSPVALGPRDRVLFIVATDLGRPARSATGVIIVGLQGEAERGP 2066
Query: 307 RFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW 366
RF ++ EA + EN+ PGTPI+ RA G NG I Y + E + + ++G
Sbjct: 2067 RFPRASSEATIRENAPPGTPIVSPRAVHAG-GTNGPITYSILSGNE--KGTFSIQPSTGA 2123
Query: 367 LSV--LHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIP 424
++V +D E +LR + A G T + L ++D NDN P R
Sbjct: 2124 ITVRSAEGLDFEVSPRLRLVLQAESGGAFAFT---VLTLTLQDANDNAP--------RFL 2172
Query: 425 LKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVP----FQLKPASDTEGDQ 480
VA + E ++ P+ V+ D DQG G ++ ++ P F + P + T
Sbjct: 2173 RPHYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAASQPARGLFHVDPTTGT---- 2228
Query: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540
+ T+ LD E E +V++A D GSP+L + +L V V DTNDN P Q
Sbjct: 2229 ------ITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNRPTIPQPW- 2281
Query: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600
E+ E+ + G +A V D DSG S S F++ G + + LD E
Sbjct: 2282 ELRVSEDALLGSEIAQVTGNDVDSGPVLWYVLS-PSGPQDPFSVGRYGGRVSLTGPLDFE 2340
Query: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660
Q DRY+ ++ A D +G + V V D NDN P F Q ++ + E+ P S +
Sbjct: 2341 QCDRYQLQLLAHDGPH---EGRANLTVLVEDVNDNAPAFSQSLYQVMLLEHTPPGSAILS 2397
Query: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYS---TMSFDREHQTTYTFRVKAVDG 717
V+ D D G N +S ++ + FS++ + GT+++ T++ + ++A D
Sbjct: 2398 VSATDRDSGANGHISYHLASPADGFSVDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDH 2457
Query: 718 GDPPRSATATVSLFVMDENDNAPTVTLPK-NISYTL-LPPSSNVRTVVATVLATDSDDG- 774
G P R+A ATV + + D+ND+AP+ TL ++ T LPP S + T+ AT D+D
Sbjct: 2458 GAPGRAARATVHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEAT----DADGSR 2513
Query: 775 INADLNYSIVGGNPFKLFEIDP--------------TSGVVSLVGKLTQKHYGLHRLVVQ 820
+A ++YSI+ GN ++F+++P G + L+ L + + L V
Sbjct: 2514 SHAAVDYSIISGNWGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVA 2573
Query: 821 VNDSGQPSQSTTTLVHVFV 839
D GQP QS+ V V V
Sbjct: 2574 AADRGQPPQSSVVPVTVTV 2592
Score = 218 bits (554), Expect = 3e-56
Identities = 227/833 (27%), Positives = 343/833 (41%), Gaps = 124/833 (14%)
Query: 35 RYRLAEE---GPADVRIGNVASDLGIVTGSGEVTFSLESGSE-YLKIDNLTGELSTSERR 90
R RL E+ GPA + + DLG + V++ L SG + + ++ + TG LS R
Sbjct: 1551 RVRLPEDQPPGPAALHVVARDPDLG---EAARVSYRLASGGDGHFRLHSSTGALSVV-RP 1606
Query: 91 IDREKLPQCQMIFDENECFLDFEVSVIG-PSQSWVDLFEGQVIVLDINDNTPTFPSPVLT 149
+DRE+ E L S G P +S + V V D+ND PTF +
Sbjct: 1607 LDREQ---------RAEHVLTVVASDHGSPPRSATQVLT--VSVADVNDEAPTFQQQEYS 1655
Query: 150 LTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGG 209
+ + EN P GT L ATD D G NG Y
Sbjct: 1656 VLLRENNPPGTSLLTLRATDPDVGANGQVTY----------------------------- 1686
Query: 210 GGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDRE 269
GG LD G L D E+Q ++
Sbjct: 1687 -------GGVSSESFSLDPDTG-------------VLTTLRALDREEQEEI--------- 1717
Query: 270 QRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQ 329
LT+ +D G PP+ + +RV + D ND++P F + ++ E P T +
Sbjct: 1718 -----NLTVYAQDRGSPPQLTHVTVRVAVEDENDHAPTFGSAHLSLEVPEGQDPQT-LTM 1771
Query: 330 LRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARD 389
LRA+D DVG NGQ++Y S LD SG + +DRE + + ARD
Sbjct: 1772 LRASDPDVGANGQLQYRILDGDPS--GAFVLDLASGEFGTMRPLDREVEPAFQLRIEARD 1829
Query: 390 RGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSD 449
GQP + + + + D ND+ P+ P+ V EDV T + +Q D
Sbjct: 1830 GGQPALSATLLLTVTVLDANDHAPA--------FPVPAYSVEVPEDVPAGTLLLQLQAHD 1881
Query: 450 RDQGENGVVTCTVVGDV--PFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVA 507
D G NG VT + F L+P+S L T+ LD E + + A
Sbjct: 1882 PDAGANGHVTYYLGAGTAGAFLLEPSSGE----------LRTAAALDREQCPSYTFSVSA 1931
Query: 508 VDSGSPS-LSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPEN----NIPGERVATVLATDA 562
VD + LS+ S+ + V D ND+ P F S + + P + P +AT+ A D
Sbjct: 1932 VDGAAAGPLSTTVSVTITVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTLALATLRAEDR 1991
Query: 563 DSGKNAEIAYSLDSSVMGIFAIDPDSGDILV-NTVLDREQTDRYEFKVNAKDKGIPVLQG 621
D+G NA I Y L + +D +G+I V + + DR F V A D G P
Sbjct: 1992 DAGANASILYRLAGTPPPGTTVDSYTGEIRVARSPVALGPRDRVLFIV-ATDLGRPARSA 2050
Query: 622 STTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEEN 681
+ +IV + + + P+F + ++EN P +P+ + A G N ++ I
Sbjct: 2051 TGVIIVGLQGEAERGPRFPRASSEATIRENAPPGTPIVSPRAVHAG-GTNGPITYSILSG 2109
Query: 682 N--NIFSIENDTG--TIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDEND 737
N FSI+ TG T+ S D E ++A GG A ++L + D ND
Sbjct: 2110 NEKGTFSIQPSTGAITVRSAEGLDFEVSPRLRLVLQAESGG---AFAFTVLTLTLQDAND 2166
Query: 738 NAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFK-LFEIDP 796
NAP P +++ LP S + + V A D D G ++YS+ P + LF +DP
Sbjct: 2167 NAPRFLRPHYVAF--LPESRPLEGPLLQVEADDLDQGSGGQISYSLAASQPARGLFHVDP 2224
Query: 797 TSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAI 849
T+G ++ L ++ + RLV+ D G P+ + + V V ++ N I
Sbjct: 2225 TTGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNRPTI 2277
Score = 216 bits (550), Expect = 9e-56
Identities = 167/580 (28%), Positives = 274/580 (47%), Gaps = 50/580 (8%)
Query: 251 TPDGEKQP--------QLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVN 302
+P G + P ++ + G LD EQ D Y+L L DG P +A L VL+ DVN
Sbjct: 2314 SPSGPQDPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHDG---PHEGRANLTVLVEDVN 2370
Query: 303 DNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDE 362
DN+P F +S+Y+ L E++ PG+ IL + A D D G NG I Y + + +D
Sbjct: 2371 DNAPAFSQSLYQVMLLEHTPPGSAILSVSATDRDSGANGHISYHLASPADG----FSVDP 2426
Query: 363 TSGWLSVLH---RIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRK 419
+G L + + + + + ARD G P + +ATV + ++D+ND+ PS +
Sbjct: 2427 NNGTLFTIVGTVALGHDGSGAVDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLSH 2486
Query: 420 IGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGEN-GVVTCTVV----GDVPFQLKP-- 472
V ED+ + + ++ +D D + V +++ G V FQL+P
Sbjct: 2487 YR--------VAVTEDLPPGSTLLTLEATDADGSRSHAAVDYSIISGNWGRV-FQLEPRL 2537
Query: 473 --ASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTND 530
A ++ G + L PLD+E+ ++N+ + A D G P SS + V V D ND
Sbjct: 2538 AEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADRGQPPQSSVVPVTVTVLDVND 2597
Query: 531 NPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDS-SVMGIFAIDPDSG 589
NPP+F ++ V PE+ G + V A+DAD G + + +++ S G+F +D SG
Sbjct: 2598 NPPVFTRASYRVTVPEDTPVGAELLHVEASDADPGPHGLVRFTVSSGDPSGLFELDESSG 2657
Query: 590 DILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVK 649
+ + LD E R++ V A D V ++V D ND+ P F ++ + V
Sbjct: 2658 TLRLAHALDCETQARHQLVVQAADPA-GAHFALAPVTIEVQDVNDHGPAFPLNLLSTSVA 2716
Query: 650 ENLQPNSPVGMVTVMDADKGRNAEMSLYI------EENNNIFSIENDTGTIYSTMSFDRE 703
EN P + V + +D D G + + E F++ + TG + + + FD E
Sbjct: 2717 ENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEGREAFALNSSTGELRARVPFDYE 2776
Query: 704 HQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVV 763
H ++ V A D G+ SA+ TVS+ V E++ P P + +P + +
Sbjct: 2777 HTESFRLLVGAADAGN--LSASVTVSVLVTGEDEYDPVFLAP--AFHFQVPEGARRGHSL 2832
Query: 764 ATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSL 803
V ATD D G + + YS+ +P+ F I+ T+G + L
Sbjct: 2833 GHVQATDEDGGADGLVLYSLATSSPY--FGINQTTGALYL 2870
Score = 202 bits (513), Expect = 2e-51
Identities = 236/849 (27%), Positives = 344/849 (40%), Gaps = 123/849 (14%)
Query: 38 LAEEGPADVRIGNVASDLGIVTGSGEVTFSLESGSEYLK---IDNLTGELSTSERRIDRE 94
+AE P +G V + +G +T+SL+ SE K I TGE++T + +DRE
Sbjct: 1114 VAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQT-LDRE 1172
Query: 95 KLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTF------PSPVL 148
+ Q++ + G S V VLD+NDN+PTF L
Sbjct: 1173 QQSSYQLLVQVQD----------GGSPPRSTTGTVHVAVLDLNDNSPTFLQASGAAGGGL 1222
Query: 149 TLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPG 208
+ V + P GTL A D D G NG Y L
Sbjct: 1223 PIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTL-------------------------- 1256
Query: 209 GGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDR 268
T PG S +F L GE L+ L R
Sbjct: 1257 --------------------------TGPG--SELFSLH---PHSGE----LLTAAPLIR 1281
Query: 269 EQRDSYELTLRVRDGGDPPRSS--QAILRVLIT--------DVNDNSPRFE-KSVYEADL 317
+R Y LTL D G PPRS+ Q +++VL + D+ + P V
Sbjct: 1282 AERPHYVLTLSAHDQGSPPRSASLQLLVQVLPSARLAEPPPDLAERDPAAPVPVVLTVTA 1341
Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEY--VFGAATESVRRLLRLDETSGWLSVLHRIDR 375
AE PG+ +L AA GV G + Y V GA E LD SG L + +D
Sbjct: 1342 AEGLRPGS-LLGSVAAPEPAGV-GALTYTLVGGADPEGT---FALDAASGRLYLARPLDF 1396
Query: 376 EEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAED 435
E R + + V + ++DEN++ P+ R PL + E+
Sbjct: 1397 EAGPPWRALTVRAEGPGGAGARLLRVQVQVQDENEHAPA-----FARDPL---ALALPEN 1448
Query: 436 VLVDTPIALVQVSDRD-QGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLD 494
+ + SD D G N V ++ P P D + L LD
Sbjct: 1449 PEPGAALYTFRASDADGPGPNSDVRYRLLRQEP----PVPALRLD--ARTGALSAPRGLD 1502
Query: 495 YEATREFNVVIVAVD---SGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPG 551
E T +++ A D + S ++ S V V D NDN P+F S V PE+ PG
Sbjct: 1503 RETTPALLLLVEATDRPANASRRRAARVSARVFVTDENDNAPVFA-SPSRVRLPEDQPPG 1561
Query: 552 ERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNA 611
V+A D D G+ A ++Y L S G F + +G + V LDREQ + V A
Sbjct: 1562 PAALHVVARDPDLGEAARVSYRLASGGDGHFRLHSSTGALSVVRPLDREQRAEHVLTVVA 1621
Query: 612 KDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRN 671
D G P + + V VAD ND P F Q ++ ++EN P + + + D D G N
Sbjct: 1622 SDHGSPPRSATQVLTVSVADVNDEAPTFQQQEYSVLLRENNPPGTSLLTLRATDPDVGAN 1681
Query: 672 AEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLF 731
+++ Y ++ FS++ DTG + + + DRE Q V A D G PP+ TV +
Sbjct: 1682 GQVT-YGGVSSESFSLDPDTGVLTTLRALDREEQEEINLTVYAQDRGSPPQLTHVTVRVA 1740
Query: 732 VMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKL 791
V DEND+APT + +L P + + A+D D G N L Y I+ G+P
Sbjct: 1741 VEDENDHAPTF---GSAHLSLEVPEGQDPQTLTMLRASDPDVGANGQLQYRILDGDPSGA 1797
Query: 792 FEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDS 851
F +D SG + L ++ +L ++ D GQP+ S T L+ V V ++ +A A
Sbjct: 1798 FVLDLASGEFGTMRPLDREVEPAFQLRIEARDGGQPALSATLLLTVTVLDANDHAPAFPV 1857
Query: 852 QIARSLHIP 860
A S+ +P
Sbjct: 1858 P-AYSVEVP 1865
Score = 188 bits (478), Expect = 2e-47
Identities = 161/547 (29%), Positives = 225/547 (41%), Gaps = 35/547 (6%)
Query: 314 EADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATES-VRRLLRLDETSGWLSVLHR 372
+ + E GT I + +A L G + Y A S V L +DE SG +
Sbjct: 48 DLQIDEEQPAGTLIGDI-SAGLPAGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTARV 106
Query: 373 IDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANV 432
+DRE+ ++ RFT + D V + + D ND+ P+ P V
Sbjct: 107 LDREQRDRYRFTAVTPDGAT------VEVTVRVADINDHAPAF--------PQARAALQV 152
Query: 433 AEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTP 492
E T L D D G G + GD + G L +
Sbjct: 153 PEHTAFGTRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPELVVTGE 212
Query: 493 LDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGE 552
LD E + + + A D GSP + L V + D ND+ P F QS E+ PG
Sbjct: 213 LDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGS 272
Query: 553 RVATVLATDADSGKNAEIAYSLD---SSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKV 609
V V A+DAD+G N + Y ++ S G F+ID +G + + LD EQ +E V
Sbjct: 273 PVLQVFASDADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVV 332
Query: 610 NAKDKGIPVLQGSTTVIVQVADKNDNDPK----FMQDVFTFYVKENLQPNSPVGMVTVMD 665
A+D G GS V V V D NDN P F+ + V E P V ++V D
Sbjct: 333 QARDGGAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVSD 392
Query: 666 ADKGRNAEMSLYIEENNNIFSIENDTGTIYSTM---SFDREHQTTYTFRVKAVDGGDPPR 722
D G A +++ +E F++ IY DRE + Y RV A D G PP
Sbjct: 393 PDDGDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARRLDREERDAYNLRVTATDSGSPPL 452
Query: 723 SATATVSLFVMDENDNAPT----VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINAD 778
A A L V D NDNAP + P+ + LP S VR V A D D G N
Sbjct: 453 RAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVR-----VTARDPDQGTNGQ 507
Query: 779 LNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVF 838
+ YS+ G F IDPTSG+++ L + +L+V D G P +++ V V
Sbjct: 508 VTYSLAPGAHTHWFSIDPTSGIITTAASLDYELEPQPQLIVVATDGGLPPLASSATVSVA 567
Query: 839 VNESVSN 845
+ + N
Sbjct: 568 LQDVNDN 574
Score = 185 bits (470), Expect = 2e-46
Identities = 210/827 (25%), Positives = 324/827 (39%), Gaps = 141/827 (17%)
Query: 64 VTFSLESGSE--YLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQ 121
VT SL G +D ++G L T R +DRE L L+ EV
Sbjct: 824 VTLSLSGGDPRGLFSLDAVSGLLQTL-RPLDRELLGPV----------LELEVRAGSGVP 872
Query: 122 SWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYE 181
+ +V++ D+NDN+P FP+P T+ + N GT A D D G N +
Sbjct: 873 PAFAVARVRVLLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIYTLRALDPDSGVNSRVTFT 932
Query: 182 LLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRS 241
LL GGG + + G R + GG
Sbjct: 933 LL------------------------AGGGGAFTVDPTTGHVRLMRPLGPSGGP------ 962
Query: 242 SVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDV 301
++EL L RDGG PPR+S LRV++ DV
Sbjct: 963 -------------------------------AHELELEARDGGSPPRTSHFRLRVVVQDV 991
Query: 302 NDN--SPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLR 359
+PRF Y DL + GT +LQ++A D G + A E
Sbjct: 992 GTRGLAPRFNSPTYRVDLPSGTTAGTQVLQVQAQAPDGG-----PITYHLAAEGASSPFG 1046
Query: 360 LDETSGWLSVLHRIDREEVNQLRFTVMA-----RDRGQPPKTDKATVVLNIKDENDNVPS 414
L+ SGWL V +DRE VMA + GQ +T ATV ++I ++N++ P
Sbjct: 1047 LEPQSGWLWVRAALDREAQELYILKVMAVSGSKAELGQ--QTGTATVRVSILNQNEHSP- 1103
Query: 415 IEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPAS 474
R+ VAE+ T + V +DRD G NG +T + L+ S
Sbjct: 1104 -------RLSEDPTFLAVAENQPPGTSVGRVFATDRDSGPNGRLT--------YSLQQLS 1148
Query: 475 DTEGDQNKKKYFLHTST-------PLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGD 527
+ + K + +H T LD E + +++ D GSP S+ ++ V V D
Sbjct: 1149 E-----DSKAFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGGSPPRSTTGTVHVAVLD 1203
Query: 528 TNDNPPMFGQSV------VEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGI 581
NDN P F Q+ + + P+ PG V T+ A D D G+N I Y+L +
Sbjct: 1204 LNDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLTGPGSEL 1263
Query: 582 FAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQV----------AD 631
F++ P SG++L L R + Y ++A D+G P S ++VQV D
Sbjct: 1264 FSLHPHSGELLTAAPLIRAERPHYVLTLSAHDQGSPPRSASLQLLVQVLPSARLAEPPPD 1323
Query: 632 KNDNDPKF-MQDVFTFYVKENLQPNSPVGMVTVMD-ADKGRNAEMSLYIEENNNIFSIEN 689
+ DP + V T E L+P S +G V + A G + + F+++
Sbjct: 1324 LAERDPAAPVPVVLTVTAAEGLRPGSLLGSVAAPEPAGVGALTYTLVGGADPEGTFALDA 1383
Query: 690 DTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNIS 749
+G +Y D E + +G + V + V DEN++AP ++
Sbjct: 1384 ASGRLYLARPLDFEAGPPWRALTVRAEGPGGAGARLLRVQVQVQDENEHAP--AFARDPL 1441
Query: 750 YTLLPPSSNVRTVVATVLATDSD-DGINADLNYSIVGGN-PFKLFEIDPTSGVVSLVGKL 807
LP + + T A+D+D G N+D+ Y ++ P +D +G +S L
Sbjct: 1442 ALALPENPEPGAALYTFRASDADGPGPNSDVRYRLLRQEPPVPALRLDARTGALSAPRGL 1501
Query: 808 TQKHYGLHRLVVQVND---SGQPSQSTTTLVHVFVNESVSNATAIDS 851
++ L+V+ D + ++ VFV + NA S
Sbjct: 1502 DRETTPALLLLVEATDRPANASRRRAARVSARVFVTDENDNAPVFAS 1548
Score = 174 bits (442), Expect = 3e-43
Identities = 204/801 (25%), Positives = 317/801 (39%), Gaps = 123/801 (15%)
Query: 52 ASDLGIVTGSGEVTFSLESGSE---YLKIDNLTGELSTSERRIDREKLPQCQMIFDENEC 108
A DL +G G++++SL + +D TG ++T+ +DRE + +++
Sbjct: 2195 ADDLDQGSG-GQISYSLAASQPARGLFHVDPTTGTITTTAI-LDREIWAETRLVL----- 2247
Query: 109 FLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTAT 168
++ S + V V+V+D NDN PT P P L V E+ +G+ T
Sbjct: 2248 -----MATDRGSPALVGSATLTVMVIDTNDNRPTIPQP-WELRVSEDALLGSEIAQVTGN 2301
Query: 169 DRDFGRNGIERYELLQEPGG------GGSGGESRRAGAAD--------------SAPYPG 208
D D +G + +L G G GG G D P+ G
Sbjct: 2302 DVD---SGPVLWYVLSPSGPQDPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHDGPHEG 2358
Query: 209 GGG----------NGASGGGS------------GGSKRRLDASEGGGGTNPGGRSSVFEL 246
N + S G + + A++ G N G S
Sbjct: 2359 RANLTVLVEDVNDNAPAFSQSLYQVMLLEHTPPGSAILSVSATDRDSGAN--GHISYHLA 2416
Query: 247 QVAD----TPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVN 302
AD P+ ++ AL + + ++ L RD G P R+++A + V + D N
Sbjct: 2417 SPADGFSVDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDHGAPGRAARATVHVQLQDQN 2476
Query: 303 DNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVG-VNGQIEYV-----FGAATESVRR 356
D++P F S Y + E+ PG+ +L L A D D + ++Y +G + R
Sbjct: 2477 DHAPSFTLSHYRVAVTEDLPPGSTLLTLEATDADGSRSHAAVDYSIISGNWGRVFQLEPR 2536
Query: 357 LLRLDETSG-------WLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDEN 409
L E++G L +L +D E + Q TV A DRGQPP++ V + + D N
Sbjct: 2537 LAEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADRGQPPQSSVVPVTVTVLDVN 2596
Query: 410 DNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQ 469
DN P + R R+ V ED V + V+ SD D G +G+V TV P
Sbjct: 2597 DN-PPVFTRASYRV-------TVPEDTPVGAELLHVEASDADPGPHGLVRFTVSSGDPSG 2648
Query: 470 LKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTN 529
L ++ G L + LD E +V+ A D + + ++V D N
Sbjct: 2649 LFELDESSGT-------LRLAHALDCETQARHQLVVQAADPAGAHFALA-PVTIEVQDVN 2700
Query: 530 DNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMG-----IFAI 584
D+ P F +++ EN PG V T+ A D D+G + YSL + G FA+
Sbjct: 2701 DHGPAFPLNLLSTSVAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEGREAFAL 2760
Query: 585 DPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVF 644
+ +G++ D E T+ + V A D G L S TV V V +++ DP F+ F
Sbjct: 2761 NSSTGELRARVPFDYEHTESFRLLVGAADAGN--LSASVTVSVLVTGEDEYDPVFLAPAF 2818
Query: 645 TFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREH 704
F V E + +G V D D G + + + ++ F I TG +Y +
Sbjct: 2819 HFQVPEGARRGHSLGHVQATDEDGGADGLVLYSLATSSPYFGINQTTGALYLRVDSRAPG 2878
Query: 705 QTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVA 764
T T + GG R A + L V+ P S TV
Sbjct: 2879 SGTAT----SGGGGRTRREAPRELRLEVIARGPL----------------PGSRSATVPV 2918
Query: 765 TVLATDSDDGINADLNYSIVG 785
TV T + G+ DLN +VG
Sbjct: 2919 TVDITHTALGLAPDLNLLLVG 2939
Score = 66.2 bits (160), Expect = 2e-10
Identities = 99/418 (23%), Positives = 158/418 (37%), Gaps = 95/418 (22%)
Query: 35 RYRLAEEGPADVRIGNVASDLGIVTGSGEVTFSLESG--SEYLKIDNLTGELSTSERRID 92
R + E+ P + +V + G V F++ SG S ++D +G L + +D
Sbjct: 2608 RVTVPEDTPVGAELLHVEASDADPGPHGLVRFTVSSGDPSGLFELDESSGTLRLAHA-LD 2666
Query: 93 REKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTLTV 152
E + Q++ V P+ + L + V D+ND+ P FP +L+ +V
Sbjct: 2667 CETQARHQLV-----------VQAADPAGAHFALAPVTIEVQDVNDHGPAFPLNLLSTSV 2715
Query: 153 EENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGGGGN 212
EN+P GTL A D D G G RY LL+ G G E R A A
Sbjct: 2716 AENQPPGTLVTTLHAIDGDAGAFGRLRYSLLE----AGPGPEGREAFA------------ 2759
Query: 213 GASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQRD 272
L++S G +L + D E +
Sbjct: 2760 -------------LNSSTG---------------------------ELRARVPFDYEHTE 2779
Query: 273 SYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRA 332
S+ L + D G+ S+ + VL+T ++ P F + + E + G + ++A
Sbjct: 2780 SFRLLVGAADAGN--LSASVTVSVLVTGEDEYDPVFLAPAFHFQVPEGARRGHSLGHVQA 2837
Query: 333 ADLDVGVNGQIEY-------VFGAATESVRRLLRLDE--------TSGWLSVLHRIDREE 377
D D G +G + Y FG + LR+D TSG R RE
Sbjct: 2838 TDEDGGADGLVLYSLATSSPYFGINQTTGALYLRVDSRAPGSGTATSGGGG---RTRREA 2894
Query: 378 VNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNV---PSIEIRKIGRIPLKDGVANV 432
+LR V+A RG P + ATV + + + + P + + +G + GV V
Sbjct: 2895 PRELRLEVIA--RGPLPGSRSATVPVTVDITHTALGLAPDLNLLLVGAVAASLGVVVV 2950
Score = 31.2 bits (69), Expect = 5.5
Identities = 55/228 (24%), Positives = 83/228 (36%), Gaps = 29/228 (12%)
Query: 33 LLRYRLAEEGPADVRIGNVASDLGIVTGSGEVTFSL------ESGSEYLKIDNLTGELST 86
LL +AE P + + + G G + +SL G E +++ TGEL
Sbjct: 2710 LLSTSVAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEGREAFALNSSTGEL-- 2767
Query: 87 SERRIDREKLPQCQMIFDENECF-LDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPS 145
R ++P ++ E F L + G + V + V+V ++ P F +
Sbjct: 2768 ------RARVP---FDYEHTESFRLLVGAADAGNLSASVTV---SVLVTGEDEYDPVFLA 2815
Query: 146 PVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAP 205
P V E G ATD D G +G+ Y L G ++ GA
Sbjct: 2816 PAFHFQVPEGARRGHSLGHVQATDEDGGADGLVLYSLAT---SSPYFGINQTTGALYLRV 2872
Query: 206 YPGGGGNGASGGGSGGSKRR-----LDASEGGGGTNPGGRSSVFELQV 248
G+G + G GG RR L G PG RS+ + V
Sbjct: 2873 DSRAPGSGTATSGGGGRTRREAPRELRLEVIARGPLPGSRSATVPVTV 2920
>gi|14270505 protocadherin gamma subfamily B, 5 isoform 2 precursor
[Homo sapiens]
Length = 818
Score = 317 bits (813), Expect = 3e-86
Identities = 229/731 (31%), Positives = 335/731 (45%), Gaps = 103/731 (14%)
Query: 20 LLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYLKID 78
L LSL A + +RYR+ EE P +GN+A+DLG V + S Y +
Sbjct: 19 LFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVS 78
Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDIND 138
+GEL S R +DRE++ + C L+FE P ++ + V + DIND
Sbjct: 79 AESGELLVSSR-LDREEI-----CGKKPACALEFEAVAENP----LNFYHVNVEIEDIND 128
Query: 139 NTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRA 198
+TP F L + E+ GT ++L A D D G N +++Y+L P E +
Sbjct: 129 HTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQ-- 186
Query: 199 GAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQP 258
D + YP EL + T D
Sbjct: 187 ---DGSKYP-------------------------------------ELALEKTLD----- 201
Query: 259 QLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLA 318
REQ+ + L L DGG PP S LR+ +TD NDN P F + VY L
Sbjct: 202 ---------REQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLR 252
Query: 319 ENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEV 378
EN PGT +LQ+ A D D G+N +I Y F ++ L+ SG ++ ++D EE
Sbjct: 253 ENVPPGTTVLQVSATDQDEGINSEITYSF----YRTGQIFSLNSKSGEITTQKKLDFEET 308
Query: 379 NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLV 438
+ V RD G + TV +NI+DENDN P + + + + E+ +
Sbjct: 309 KEYSMVVEGRDGG--GLVAQCTVEINIQDENDNSPEVTFHSL--------LEMILENAVP 358
Query: 439 DTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEAT 498
T IAL+++ D+D GENG V C + G+VPF++ +S K Y L T LD E T
Sbjct: 359 GTLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSS-------KNSYKLVTDGTLDREQT 411
Query: 499 REFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVL 558
E+NV I A D G P LSS+ S+I+ + D NDN P+F Q+ V PENN PG +A V
Sbjct: 412 PEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIAQVC 471
Query: 559 ATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAK 612
A+D D G N +++YS+ +S + ++ SG + D EQ +E + A+
Sbjct: 472 ASDLDLGLNGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDYEQLRTFELTLQAR 531
Query: 613 DKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNSPVGMVTVMD 665
D+G P L + ++ V V D+NDN P+ + V +P V V +D
Sbjct: 532 DQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVD 591
Query: 666 ADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRS 723
AD G NA +S ++ + + +FS+ TG + + + V DGG PP S
Sbjct: 592 ADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLS 651
Query: 724 ATATVSLFVMD 734
ATAT+ L D
Sbjct: 652 ATATLHLVFAD 662
Score = 237 bits (604), Expect = 5e-62
Identities = 183/670 (27%), Positives = 314/670 (46%), Gaps = 56/670 (8%)
Query: 259 QLIVKGALDREQRDSYE--LTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEAD 316
+L+V LDRE+ + L + P + + V I D+ND++P+F ++ +E
Sbjct: 83 ELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHV-NVEIEDINDHTPKFTQNSFELQ 141
Query: 317 LAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW--LSVLHRID 374
++E++ PGT + A D D+G+N +Y + + S + L++ +D
Sbjct: 142 ISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALEKTLD 201
Query: 375 REEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAE 434
RE+ + R + A D G PP + + + + D NDN P R + R+ L+ E
Sbjct: 202 REQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFN-RDVYRVSLR-------E 253
Query: 435 DVLVDTPIALVQVSDRDQGENGVVTCTV--VGDVPFQLKPASDTEGDQNKKKYFLHTSTP 492
+V T + V +D+D+G N +T + G + F L N K + T
Sbjct: 254 NVPPGTTVLQVSATDQDEGINSEITYSFYRTGQI-FSL----------NSKSGEITTQKK 302
Query: 493 LDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPP-MFGQSVVEVYFPENNIPG 551
LD+E T+E+++V+ D G L + ++ + + D NDN P + S++E+ EN +PG
Sbjct: 303 LDFEETKEYSMVVEGRDGGG--LVAQCTVEINIQDENDNSPEVTFHSLLEMIL-ENAVPG 359
Query: 552 ERVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFKVN 610
+A + D DSG+N E+ L V I + +S ++ + LDREQT Y +
Sbjct: 360 TLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTIT 419
Query: 611 AKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGR 670
A D+G P L S +VI+ + D NDN P F Q + V EN P + + V D D G
Sbjct: 420 ATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIAQVCASDLDLGL 479
Query: 671 NAEMSLYIEENN-------NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRS 723
N ++S I ++ + S+ +G +++ +FD E T+ ++A D G P S
Sbjct: 480 NGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDYEQLRTFELTLQARDQGSPALS 539
Query: 724 ATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGINAD 778
A ++ + V D NDNAP V P + + ++P ++ +V V+A D+D G NA
Sbjct: 540 ANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAW 599
Query: 779 LNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVF 838
L+Y ++ + LF + +G V L + RL+V V D GQP S T +H+
Sbjct: 600 LSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLV 659
Query: 839 VNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIV 898
+S+ L + + DP E+ + +V+ + + +L +++
Sbjct: 660 FADSLQEV----------LPDITDRPVPSDPQAEL---QFYLVVALALISVLFLLAVILA 706
Query: 899 VMARYCRSKN 908
V R RS +
Sbjct: 707 VALRLRRSSS 716
Score = 101 bits (252), Expect = 3e-21
Identities = 80/269 (29%), Positives = 130/269 (48%), Gaps = 35/269 (13%)
Query: 576 SSVMGIFAIDPDSGDILVNTVLDREQ------TDRYEFKVNAKDKGIPVLQGSTTVIVQV 629
SS F + +SG++LV++ LDRE+ EF+ A++ V V++
Sbjct: 69 SSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENP-----LNFYHVNVEI 123
Query: 630 ADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNA--EMSLYIEENNNIFSI 687
D ND+ PKF Q+ F + E+ QP + + DAD G N+ + L + + ++
Sbjct: 124 EDINDHTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIK 183
Query: 688 ENDTGTIYSTM----SFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-- 741
E G+ Y + + DRE Q+ + + A+DGG PP S T + + V D NDN P
Sbjct: 184 EKQDGSKYPELALEKTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFN 243
Query: 742 -----VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDP 796
V+L +N+ PP T V V ATD D+GIN+++ YS ++F ++
Sbjct: 244 RDVYRVSLRENV-----PPG----TTVLQVSATDQDEGINSEITYSFY--RTGQIFSLNS 292
Query: 797 TSGVVSLVGKLTQKHYGLHRLVVQVNDSG 825
SG ++ KL + + +VV+ D G
Sbjct: 293 KSGEITTQKKLDFEETKEYSMVVEGRDGG 321
>gi|11128031 protocadherin gamma subfamily B, 5 isoform 1 precursor
[Homo sapiens]
Length = 923
Score = 317 bits (813), Expect = 3e-86
Identities = 229/731 (31%), Positives = 335/731 (45%), Gaps = 103/731 (14%)
Query: 20 LLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYLKID 78
L LSL A + +RYR+ EE P +GN+A+DLG V + S Y +
Sbjct: 19 LFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVS 78
Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDIND 138
+GEL S R +DRE++ + C L+FE P ++ + V + DIND
Sbjct: 79 AESGELLVSSR-LDREEI-----CGKKPACALEFEAVAENP----LNFYHVNVEIEDIND 128
Query: 139 NTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRA 198
+TP F L + E+ GT ++L A D D G N +++Y+L P E +
Sbjct: 129 HTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQ-- 186
Query: 199 GAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQP 258
D + YP EL + T D
Sbjct: 187 ---DGSKYP-------------------------------------ELALEKTLD----- 201
Query: 259 QLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLA 318
REQ+ + L L DGG PP S LR+ +TD NDN P F + VY L
Sbjct: 202 ---------REQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLR 252
Query: 319 ENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEV 378
EN PGT +LQ+ A D D G+N +I Y F ++ L+ SG ++ ++D EE
Sbjct: 253 ENVPPGTTVLQVSATDQDEGINSEITYSF----YRTGQIFSLNSKSGEITTQKKLDFEET 308
Query: 379 NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLV 438
+ V RD G + TV +NI+DENDN P + + + + E+ +
Sbjct: 309 KEYSMVVEGRDGG--GLVAQCTVEINIQDENDNSPEVTFHSL--------LEMILENAVP 358
Query: 439 DTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEAT 498
T IAL+++ D+D GENG V C + G+VPF++ +S K Y L T LD E T
Sbjct: 359 GTLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSS-------KNSYKLVTDGTLDREQT 411
Query: 499 REFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVL 558
E+NV I A D G P LSS+ S+I+ + D NDN P+F Q+ V PENN PG +A V
Sbjct: 412 PEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIAQVC 471
Query: 559 ATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAK 612
A+D D G N +++YS+ +S + ++ SG + D EQ +E + A+
Sbjct: 472 ASDLDLGLNGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDYEQLRTFELTLQAR 531
Query: 613 DKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNSPVGMVTVMD 665
D+G P L + ++ V V D+NDN P+ + V +P V V +D
Sbjct: 532 DQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVD 591
Query: 666 ADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRS 723
AD G NA +S ++ + + +FS+ TG + + + V DGG PP S
Sbjct: 592 ADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLS 651
Query: 724 ATATVSLFVMD 734
ATAT+ L D
Sbjct: 652 ATATLHLVFAD 662
Score = 237 bits (604), Expect = 5e-62
Identities = 183/670 (27%), Positives = 314/670 (46%), Gaps = 56/670 (8%)
Query: 259 QLIVKGALDREQRDSYE--LTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEAD 316
+L+V LDRE+ + L + P + + V I D+ND++P+F ++ +E
Sbjct: 83 ELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHV-NVEIEDINDHTPKFTQNSFELQ 141
Query: 317 LAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW--LSVLHRID 374
++E++ PGT + A D D+G+N +Y + + S + L++ +D
Sbjct: 142 ISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALEKTLD 201
Query: 375 REEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAE 434
RE+ + R + A D G PP + + + + D NDN P R + R+ L+ E
Sbjct: 202 REQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFN-RDVYRVSLR-------E 253
Query: 435 DVLVDTPIALVQVSDRDQGENGVVTCTV--VGDVPFQLKPASDTEGDQNKKKYFLHTSTP 492
+V T + V +D+D+G N +T + G + F L N K + T
Sbjct: 254 NVPPGTTVLQVSATDQDEGINSEITYSFYRTGQI-FSL----------NSKSGEITTQKK 302
Query: 493 LDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPP-MFGQSVVEVYFPENNIPG 551
LD+E T+E+++V+ D G L + ++ + + D NDN P + S++E+ EN +PG
Sbjct: 303 LDFEETKEYSMVVEGRDGGG--LVAQCTVEINIQDENDNSPEVTFHSLLEMIL-ENAVPG 359
Query: 552 ERVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFKVN 610
+A + D DSG+N E+ L V I + +S ++ + LDREQT Y +
Sbjct: 360 TLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTIT 419
Query: 611 AKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGR 670
A D+G P L S +VI+ + D NDN P F Q + V EN P + + V D D G
Sbjct: 420 ATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIAQVCASDLDLGL 479
Query: 671 NAEMSLYIEENN-------NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRS 723
N ++S I ++ + S+ +G +++ +FD E T+ ++A D G P S
Sbjct: 480 NGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDYEQLRTFELTLQARDQGSPALS 539
Query: 724 ATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGINAD 778
A ++ + V D NDNAP V P + + ++P ++ +V V+A D+D G NA
Sbjct: 540 ANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAW 599
Query: 779 LNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVF 838
L+Y ++ + LF + +G V L + RL+V V D GQP S T +H+
Sbjct: 600 LSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLV 659
Query: 839 VNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIV 898
+S+ L + + DP E+ + +V+ + + +L +++
Sbjct: 660 FADSLQEV----------LPDITDRPVPSDPQAEL---QFYLVVALALISVLFLLAVILA 706
Query: 899 VMARYCRSKN 908
V R RS +
Sbjct: 707 VALRLRRSSS 716
Score = 101 bits (252), Expect = 3e-21
Identities = 80/269 (29%), Positives = 130/269 (48%), Gaps = 35/269 (13%)
Query: 576 SSVMGIFAIDPDSGDILVNTVLDREQ------TDRYEFKVNAKDKGIPVLQGSTTVIVQV 629
SS F + +SG++LV++ LDRE+ EF+ A++ V V++
Sbjct: 69 SSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENP-----LNFYHVNVEI 123
Query: 630 ADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNA--EMSLYIEENNNIFSI 687
D ND+ PKF Q+ F + E+ QP + + DAD G N+ + L + + ++
Sbjct: 124 EDINDHTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIK 183
Query: 688 ENDTGTIYSTM----SFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-- 741
E G+ Y + + DRE Q+ + + A+DGG PP S T + + V D NDN P
Sbjct: 184 EKQDGSKYPELALEKTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFN 243
Query: 742 -----VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDP 796
V+L +N+ PP T V V ATD D+GIN+++ YS ++F ++
Sbjct: 244 RDVYRVSLRENV-----PPG----TTVLQVSATDQDEGINSEITYSFY--RTGQIFSLNS 292
Query: 797 TSGVVSLVGKLTQKHYGLHRLVVQVNDSG 825
SG ++ KL + + +VV+ D G
Sbjct: 293 KSGEITTQKKLDFEETKEYSMVVEGRDGG 321
>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 315 bits (808), Expect = 1e-85
Identities = 243/748 (32%), Positives = 349/748 (46%), Gaps = 109/748 (14%)
Query: 18 CLLLPLSLSLAAAKQL----LRYRLAEEGPADVRIGNVASDLGIVTGS---GEVTFSLES 70
CLLL SL L AA ++ L Y ++EE +G +A DLG+ + +
Sbjct: 13 CLLL--SLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKR 70
Query: 71 GSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQ 130
+ L+++ G L + R IDRE+L C EC + EV V P Q +F +
Sbjct: 71 HGDLLEVNLQNGILFVNSR-IDREEL--CGR---SAECSIHLEVIVDRPLQ----VFHVE 120
Query: 131 VIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGG 190
V V DINDN P FP V L + E+R G+ + L A+D D G N + Y L
Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSL-------- 172
Query: 191 SGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVAD 250
DS Y F L V
Sbjct: 173 -----------DSTEY-------------------------------------FTLDVKR 184
Query: 251 TPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEK 310
+ K L++K L+RE + L + DGG P + L++ + DVNDN+P FE+
Sbjct: 185 NDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFER 244
Query: 311 SVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGA-ATESVRRLLRLDETSGWLSV 369
++Y+ L EN+ GT ++ + A DLD GVN I Y F + + LD +G +SV
Sbjct: 245 TIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISV 304
Query: 370 LHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGV 429
ID EE V A D+G PP +D TV+L I D NDNVP + I+ + +P
Sbjct: 305 KGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLS-LP----- 358
Query: 430 ANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHT 489
V ED + T IAL+ VSDRD G NG VTC++ VPF+L K Y L
Sbjct: 359 --VLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTF-------KNYYSLVL 409
Query: 490 STPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNI 549
+PLD E+ + +V+ A D GSPSL + S+ V+V D NDN P F QS V+ ENN
Sbjct: 410 DSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNP 469
Query: 550 PGERVATVLATDADSGKNAEIAYSL------DSSVMGIFAIDPDSGDILVNTVLDREQTD 603
PG + TV A DAD+ +NA ++YSL + ++ ++ +SG + LD E+ +
Sbjct: 470 PGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELE 529
Query: 604 RYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNS 656
+F+V+A+D G+P L + T+ V V D+NDN P + + V ++
Sbjct: 530 LLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGH 589
Query: 657 PVGMVTVMDADKGRNAEMSLYIEENNN----IFSIENDTGTIYSTMSFDREHQTTYTFRV 712
V V +DAD G NA +S ++ F + TG I +T + D + V
Sbjct: 590 VVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLV 649
Query: 713 KAVDGGDPPRSATATVSLFVMDENDNAP 740
D G+P +ATATV L + E+ AP
Sbjct: 650 LVKDHGEPSLTATATV-LVSLVESGQAP 676
Score = 233 bits (593), Expect = 9e-61
Identities = 184/678 (27%), Positives = 313/678 (46%), Gaps = 57/678 (8%)
Query: 260 LIVKGALDREQR--DSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317
L V +DRE+ S E ++ + D P + V + D+NDN+P F +V +
Sbjct: 84 LFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV-EVEVKDINDNAPVFPMAVKNLFI 142
Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHR--IDR 375
+E+ PG+ A+D D+G N + Y + + R DE L ++ + ++R
Sbjct: 143 SESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGLVLKKNLNR 202
Query: 376 EEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAED 435
E+ + + A D G+P T + + + D NDN P+ E R I ++ L + N
Sbjct: 203 EDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFE-RTIYKVRLLENAPN---- 257
Query: 436 VLVDTPIALVQVSDRDQGENGVVTCTVVGDVP------FQLKPASDTEGDQNKKKYFLHT 489
T + V +D D+G N + + D+ F L P + +
Sbjct: 258 ---GTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQ----------ISV 304
Query: 490 STPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNI 549
+D+E ++ + + + A D G+P +S + ++++++ D NDN P + + E++
Sbjct: 305 KGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSP 364
Query: 550 PGERVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFK 608
+A + +D DSG N ++ SL V + + + +++++ LDRE YE
Sbjct: 365 LSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELV 424
Query: 609 VNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADK 668
V A+D G P L + +V V+VAD NDN P F Q +T +VKEN P + V+ DAD
Sbjct: 425 VTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADA 484
Query: 669 GRNAEMSLYIEEN-------NNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPP 721
NA +S + E ++ S+ ++G +Y+ D E F+V A D G PP
Sbjct: 485 QENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPP 544
Query: 722 RSATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGIN 776
+ T+ +FV+DENDNAP + +P+ L+P S VVA V A D+D G N
Sbjct: 545 LGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYN 604
Query: 777 ADLNYSI---VGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTT 833
A L+Y + GG F + +G +S L + HRL+V V D G+PS + T
Sbjct: 605 AWLSYELQPGTGGARIP-FRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATA 663
Query: 834 LVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVIL 893
V V + ES A SQ + A P + + +++ + A + ++++
Sbjct: 664 TVLVSLVES-GQAPKASSQASAG---------ATGPEAALVDVNVYLIVAICA-VSSLLV 712
Query: 894 IILIVVMARYCRSKNKNG 911
+ L++ A C + G
Sbjct: 713 LTLLLYTALRCSAPPTEG 730
Score = 182 bits (463), Expect = 1e-45
Identities = 161/552 (29%), Positives = 257/552 (46%), Gaps = 40/552 (7%)
Query: 317 LAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDRE 376
++E + GT + ++ A DL + + + +F A++ LL ++ +G L V RIDRE
Sbjct: 35 VSEEAKHGTFVGRI-AQDLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDRE 93
Query: 377 EV------NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 430
E+ + V+ DR V + +KD NDN P P+
Sbjct: 94 ELCGRSAECSIHLEVIV-DR----PLQVFHVEVEVKDINDNAPV--------FPMAVKNL 140
Query: 431 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 490
++E + +L SD D G N ++T ++ F L D+ K L
Sbjct: 141 FISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL---DVKRNDEEIKSLGLVLK 197
Query: 491 TPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIP 550
L+ E T + ++I A+D G P L+ L + V D NDN P F +++ +V EN
Sbjct: 198 KNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPN 257
Query: 551 GERVATVLATDADSGKNAEIAYS----LDSSVMGIFAIDPDSGDILVNTVLDREQTDRYE 606
G V TV ATD D G N +IAYS + + ++ F +DP +G I V +D E++ YE
Sbjct: 258 GTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYE 317
Query: 607 FKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDA 666
+V A DKG P + TV++++ D NDN P+ + + V E+ ++ + +++V D
Sbjct: 318 IQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISVSDR 377
Query: 667 DKGRNAEMSLYIEENNNIFSIENDTGTIYSTM---SFDREHQTTYTFRVKAVDGGDPPRS 723
D G N +++ + + F + + YS + DRE + Y V A DGG P
Sbjct: 378 DSGVNGQVTCSLTPHVP-FKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLW 436
Query: 724 ATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTV-VATVLATDSDDGINADLNYS 782
ATA+VS+ V D NDNAP + YT+ +N + TV A D+D NA ++YS
Sbjct: 437 ATASVSVEVADVNDNAPAFS---QSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493
Query: 783 I----VGGNPFKLF-EIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837
+ VG + + SG V + L + L + V D+G P + + V
Sbjct: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553
Query: 838 FVNESVSNATAI 849
FV + NA A+
Sbjct: 554 FVLDENDNAPAL 565
>gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo
sapiens]
Length = 824
Score = 315 bits (808), Expect = 1e-85
Identities = 243/748 (32%), Positives = 349/748 (46%), Gaps = 109/748 (14%)
Query: 18 CLLLPLSLSLAAAKQL----LRYRLAEEGPADVRIGNVASDLGIVTGS---GEVTFSLES 70
CLLL SL L AA ++ L Y ++EE +G +A DLG+ + +
Sbjct: 13 CLLL--SLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKR 70
Query: 71 GSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQ 130
+ L+++ G L + R IDRE+L C EC + EV V P Q +F +
Sbjct: 71 HGDLLEVNLQNGILFVNSR-IDREEL--CGR---SAECSIHLEVIVDRPLQ----VFHVE 120
Query: 131 VIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGG 190
V V DINDN P FP V L + E+R G+ + L A+D D G N + Y L
Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSL-------- 172
Query: 191 SGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVAD 250
DS Y F L V
Sbjct: 173 -----------DSTEY-------------------------------------FTLDVKR 184
Query: 251 TPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEK 310
+ K L++K L+RE + L + DGG P + L++ + DVNDN+P FE+
Sbjct: 185 NDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFER 244
Query: 311 SVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGA-ATESVRRLLRLDETSGWLSV 369
++Y+ L EN+ GT ++ + A DLD GVN I Y F + + LD +G +SV
Sbjct: 245 TIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISV 304
Query: 370 LHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGV 429
ID EE V A D+G PP +D TV+L I D NDNVP + I+ + +P
Sbjct: 305 KGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLS-LP----- 358
Query: 430 ANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHT 489
V ED + T IAL+ VSDRD G NG VTC++ VPF+L K Y L
Sbjct: 359 --VLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTF-------KNYYSLVL 409
Query: 490 STPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNI 549
+PLD E+ + +V+ A D GSPSL + S+ V+V D NDN P F QS V+ ENN
Sbjct: 410 DSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNP 469
Query: 550 PGERVATVLATDADSGKNAEIAYSL------DSSVMGIFAIDPDSGDILVNTVLDREQTD 603
PG + TV A DAD+ +NA ++YSL + ++ ++ +SG + LD E+ +
Sbjct: 470 PGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELE 529
Query: 604 RYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNS 656
+F+V+A+D G+P L + T+ V V D+NDN P + + V ++
Sbjct: 530 LLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGH 589
Query: 657 PVGMVTVMDADKGRNAEMSLYIEENNN----IFSIENDTGTIYSTMSFDREHQTTYTFRV 712
V V +DAD G NA +S ++ F + TG I +T + D + V
Sbjct: 590 VVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLV 649
Query: 713 KAVDGGDPPRSATATVSLFVMDENDNAP 740
D G+P +ATATV L + E+ AP
Sbjct: 650 LVKDHGEPSLTATATV-LVSLVESGQAP 676
Score = 233 bits (593), Expect = 9e-61
Identities = 184/678 (27%), Positives = 313/678 (46%), Gaps = 57/678 (8%)
Query: 260 LIVKGALDREQR--DSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317
L V +DRE+ S E ++ + D P + V + D+NDN+P F +V +
Sbjct: 84 LFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV-EVEVKDINDNAPVFPMAVKNLFI 142
Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHR--IDR 375
+E+ PG+ A+D D+G N + Y + + R DE L ++ + ++R
Sbjct: 143 SESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGLVLKKNLNR 202
Query: 376 EEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAED 435
E+ + + A D G+P T + + + D NDN P+ E R I ++ L + N
Sbjct: 203 EDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFE-RTIYKVRLLENAPN---- 257
Query: 436 VLVDTPIALVQVSDRDQGENGVVTCTVVGDVP------FQLKPASDTEGDQNKKKYFLHT 489
T + V +D D+G N + + D+ F L P + +
Sbjct: 258 ---GTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQ----------ISV 304
Query: 490 STPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNI 549
+D+E ++ + + + A D G+P +S + ++++++ D NDN P + + E++
Sbjct: 305 KGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSP 364
Query: 550 PGERVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFK 608
+A + +D DSG N ++ SL V + + + +++++ LDRE YE
Sbjct: 365 LSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELV 424
Query: 609 VNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADK 668
V A+D G P L + +V V+VAD NDN P F Q +T +VKEN P + V+ DAD
Sbjct: 425 VTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADA 484
Query: 669 GRNAEMSLYIEEN-------NNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPP 721
NA +S + E ++ S+ ++G +Y+ D E F+V A D G PP
Sbjct: 485 QENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPP 544
Query: 722 RSATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGIN 776
+ T+ +FV+DENDNAP + +P+ L+P S VVA V A D+D G N
Sbjct: 545 LGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYN 604
Query: 777 ADLNYSI---VGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTT 833
A L+Y + GG F + +G +S L + HRL+V V D G+PS + T
Sbjct: 605 AWLSYELQPGTGGARIP-FRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATA 663
Query: 834 LVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVIL 893
V V + ES A SQ + A P + + +++ + A + ++++
Sbjct: 664 TVLVSLVES-GQAPKASSQASAG---------ATGPEAALVDVNVYLIVAICA-VSSLLV 712
Query: 894 IILIVVMARYCRSKNKNG 911
+ L++ A C + G
Sbjct: 713 LTLLLYTALRCSAPPTEG 730
Score = 182 bits (463), Expect = 1e-45
Identities = 161/552 (29%), Positives = 257/552 (46%), Gaps = 40/552 (7%)
Query: 317 LAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDRE 376
++E + GT + ++ A DL + + + +F A++ LL ++ +G L V RIDRE
Sbjct: 35 VSEEAKHGTFVGRI-AQDLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDRE 93
Query: 377 EV------NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 430
E+ + V+ DR V + +KD NDN P P+
Sbjct: 94 ELCGRSAECSIHLEVIV-DR----PLQVFHVEVEVKDINDNAPV--------FPMAVKNL 140
Query: 431 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 490
++E + +L SD D G N ++T ++ F L D+ K L
Sbjct: 141 FISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL---DVKRNDEEIKSLGLVLK 197
Query: 491 TPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIP 550
L+ E T + ++I A+D G P L+ L + V D NDN P F +++ +V EN
Sbjct: 198 KNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPN 257
Query: 551 GERVATVLATDADSGKNAEIAYS----LDSSVMGIFAIDPDSGDILVNTVLDREQTDRYE 606
G V TV ATD D G N +IAYS + + ++ F +DP +G I V +D E++ YE
Sbjct: 258 GTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYE 317
Query: 607 FKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDA 666
+V A DKG P + TV++++ D NDN P+ + + V E+ ++ + +++V D
Sbjct: 318 IQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISVSDR 377
Query: 667 DKGRNAEMSLYIEENNNIFSIENDTGTIYSTM---SFDREHQTTYTFRVKAVDGGDPPRS 723
D G N +++ + + F + + YS + DRE + Y V A DGG P
Sbjct: 378 DSGVNGQVTCSLTPHVP-FKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLW 436
Query: 724 ATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTV-VATVLATDSDDGINADLNYS 782
ATA+VS+ V D NDNAP + YT+ +N + TV A D+D NA ++YS
Sbjct: 437 ATASVSVEVADVNDNAPAFS---QSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493
Query: 783 I----VGGNPFKLF-EIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837
+ VG + + SG V + L + L + V D+G P + + V
Sbjct: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553
Query: 838 FVNESVSNATAI 849
FV + NA A+
Sbjct: 554 FVLDENDNAPAL 565
>gi|11036656 protocadherin beta 7 precursor [Homo sapiens]
Length = 793
Score = 312 bits (800), Expect = 9e-85
Identities = 233/769 (30%), Positives = 358/769 (46%), Gaps = 124/769 (16%)
Query: 23 LSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSGEVT-----FSLESGSEYLKI 77
L +S A A+ L RY +AEE + N+A DLG+ G GE+ + + L +
Sbjct: 21 LGMSWAGAEPL-RYFVAEETERGTFLTNLAKDLGL--GVGELRARGTRIVSDQNMQILLL 77
Query: 78 DNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDIN 137
+LTG+L +E+ +DRE+L C L F++ + P Q +F ++ V DIN
Sbjct: 78 SSLTGDLLLNEK-LDREEL-----CGPREPCVLPFQLLLEKPFQ----IFRAELWVRDIN 127
Query: 138 DNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRR 197
D+ P F ++L + E+ G +LL +A D D G N + Y +
Sbjct: 128 DHAPVFLDREISLKILESTTPGAAFLLESAQDSDVGTNSLSNYTI--------------- 172
Query: 198 AGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQ 257
S + ++ + G G + EL + D E+
Sbjct: 173 ---------------------SPNAYFHINVHDSGEG------NIYPELVLNQVLDREEI 205
Query: 258 PQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317
P+ + LTL DGG PPRS A++R+L+ DVNDN+P F +S+Y+ +
Sbjct: 206 PE--------------FSLTLTALDGGSPPRSGTALVRILVLDVNDNAPDFVRSLYKVQV 251
Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREE 377
ENS G+ ++ + A DLD G NG+I Y F ATE + + +++ TSG L + ++D E
Sbjct: 252 PENSPVGSMVVSVSARDLDTGSNGEIAYAFSYATERILKTFQINPTSGSLHLKAQLDYEA 311
Query: 378 VNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVL 437
+ T+ A+D G + K TVV+++ D NDN P + + + + +AE+
Sbjct: 312 IQTYTLTIQAKDGG--GLSGKCTVVVDVTDINDNRPELLLSSL--------TSPIAEN-S 360
Query: 438 VDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEA 497
+T +A+ ++ DRD G NG C++ DVPF LKP+ + Y L T PLD E
Sbjct: 361 PETVVAVFRIRDRDSGNNGKTVCSIQDDVPFILKPSVE-------NFYTLVTEKPLDRER 413
Query: 498 TREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATV 557
E+N+ I D G+P L + +++ V V D NDN P F Q+ ++ ENN P + +V
Sbjct: 414 NTEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALPIGSV 473
Query: 558 LATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNA 611
ATD DSG NA++ YSL S + + +I+ D+G + LD E +EF+V A
Sbjct: 474 SATDRDSGTNAQVIYSLLPSQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGA 533
Query: 612 KDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKEN------------LQPNSPVG 659
D+G P L V V V D NDN P F Y +N +P V
Sbjct: 534 TDRGSPALSSEALVRVLVLDANDNSP------FVLYPLQNSSAPCTEPLPRAAEPGYLVT 587
Query: 660 MVTVMDADKGRNAEMS--LYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDG 717
V +D D G+NA +S L +F + G + + V D
Sbjct: 588 KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKQRLVVLVKDN 647
Query: 718 GDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATV 766
G+PPRSATAT+ + ++D + P + LP+ P +N TV V
Sbjct: 648 GEPPRSATATLHVLLVD-GFSQPYLRLPE-----AAPDQANSLTVYLVV 690
Score = 229 bits (584), Expect = 1e-59
Identities = 185/629 (29%), Positives = 283/629 (44%), Gaps = 59/629 (9%)
Query: 298 ITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRL 357
+ D+ND++P F + E++ PG L A D DVG N Y + + +
Sbjct: 123 VRDINDHAPVFLDREISLKILESTTPGAAFLLESAQDSDVGTNSLSNYTI--SPNAYFHI 180
Query: 358 LRLDETSGWLS---VLHRI-DREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVP 413
D G + VL+++ DREE+ + T+ A D G PP++ A V + + D NDN P
Sbjct: 181 NVHDSGEGNIYPELVLNQVLDREEIPEFSLTLTALDGGSPPRSGTALVRILVLDVNDNAP 240
Query: 414 SIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVP-----F 468
+R + ++ V E+ V + + V D D G NG + F
Sbjct: 241 DF-VRSLYKV-------QVPENSPVGSMVVSVSARDLDTGSNGEIAYAFSYATERILKTF 292
Query: 469 QLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDT 528
Q+ P S + LH LDYEA + + + I A D G LS +++V V D
Sbjct: 293 QINPTSGS----------LHLKAQLDYEAIQTYTLTIQAKDGGG--LSGKCTVVVDVTDI 340
Query: 529 NDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDS 588
NDN P S + EN+ P VA D DSG N + S+ V I ++
Sbjct: 341 NDNRPELLLSSLTSPIAENS-PETVVAVFRIRDRDSGNNGKTVCSIQDDVPFILKPSVEN 399
Query: 589 GDILVNTV-LDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFY 647
LV LDRE+ Y + D G P L+ + V V+D NDN P F Q +T +
Sbjct: 400 FYTLVTEKPLDRERNTEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLF 459
Query: 648 VKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNN-------IFSIENDTGTIYSTMSF 700
V+EN P P+G V+ D D G NA++ + + + + SI D G +++ S
Sbjct: 460 VRENNSPALPIGSVSATDRDSGTNAQVIYSLLPSQDPHLPLASLVSINADNGHLFALRSL 519
Query: 701 DREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTL----LPPS 756
D E + FRV A D G P S+ A V + V+D NDN+P V P S LP +
Sbjct: 520 DYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNSSAPCTEPLPRA 579
Query: 757 SNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHR 816
+ +V V+A D D G NA L+Y ++ LF + +G V L+++ R
Sbjct: 580 AEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKQR 639
Query: 817 LVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQ 876
LVV V D+G+P +S T +HV + +D L +P + A D + ++
Sbjct: 640 LVVLVKDNGEPPRSATATLHVLL---------VDGFSQPYLRLP---EAAPDQANSLT-- 685
Query: 877 RLSIVIGVVAGIMTVILIILIVVMARYCR 905
+ +V+ + + +L +L+ V R CR
Sbjct: 686 -VYLVVALASVSSLFLLSVLLFVAVRLCR 713
>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
Length = 1040
Score = 312 bits (799), Expect = 1e-84
Identities = 237/758 (31%), Positives = 344/758 (45%), Gaps = 124/758 (16%)
Query: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI----VTGSGEVTFSLESGSEY 74
LL L + L Y + EE +GN+A DLG+ ++ G T S + Y
Sbjct: 5 LLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVP-NSRTPY 63
Query: 75 LKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVL 134
L ++ TG L +E+ IDRE++ C+ C L EV + P ++LF+ ++ VL
Sbjct: 64 LDLNLETGVLYVNEK-IDREQI--CKQ---SPSCVLHLEVFLENP----LELFQVEIEVL 113
Query: 135 DINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYEL---------LQE 185
DINDN P+FP P LT+ + E+ GT + L +A D D G N + YE+ +Q
Sbjct: 114 DINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQT 173
Query: 186 PGGGGSGGESRRAGAADS----------APYPGGGGNGASGGGSGGSKRRLDASEGGGGT 235
G G E D GGGG G GG GG GG G
Sbjct: 174 QGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGG---------GGAGL 224
Query: 236 NPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILR 295
P R+ A+L
Sbjct: 225 PP-----------------------------------------------QQQRTGTALLT 237
Query: 296 VLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGA-ATESV 354
+ + D NDN P F++ VY L ENS PGT ++QL A D D G NG++ Y F + +
Sbjct: 238 IRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRA 297
Query: 355 RRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPS 414
R L L +G L V +D EE + V A+D G V++ + D NDN P
Sbjct: 298 RELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPE 357
Query: 415 IEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPAS 474
I + V+E T +AL V+DRD ENG V C ++GDVPF+LK +
Sbjct: 358 ISFSTVKEA--------VSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSF 409
Query: 475 DTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPM 534
K Y + T PLD EA + + +VA D G P+LS++ S+ V+V D NDN P
Sbjct: 410 -------KNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPR 462
Query: 535 FGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSL------DSSVMGIFAIDPDS 588
F Q V +VY ENN+PG + V ATD D G NA++AYS+ SV +I+ ++
Sbjct: 463 FSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSEN 522
Query: 589 GDILVNTVLDREQTDRYEFKVNAKDKGIP-VLQGSTTVIVQVADKNDNDPKFMQDV---- 643
G + D EQ + F+V A+D G P L G+ TV + + D+NDN P + +
Sbjct: 523 GYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRN 582
Query: 644 ---FTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIFSIENDTGTIYST- 697
+ + +P + V +DAD G NA ++ I N N+F ++ TG + +
Sbjct: 583 GTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTAR 642
Query: 698 -MSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMD 734
+ R+ Q Y ++ D G PP S+TAT+ + ++D
Sbjct: 643 RVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680
Score = 234 bits (597), Expect = 3e-61
Identities = 192/660 (29%), Positives = 310/660 (46%), Gaps = 66/660 (10%)
Query: 294 LRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATES 353
+ + + D+NDN P F + +++E++ PGT A D DVG N +Y +
Sbjct: 108 VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEI-----T 162
Query: 354 VRRLLRLD-ETSG------WLSVLHRIDREEVNQLRFTVMARDRG--------------- 391
LD +T G L + +DRE+ R+ + A D G
Sbjct: 163 PNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGA 222
Query: 392 ----QPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQV 447
Q +T A + + + D NDNVP+ + ++ E+ T + +
Sbjct: 223 GLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVY--------TVSLPENSPPGTLVIQLNA 274
Query: 448 SDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVA 507
+D D+G+NG VV + P + + + L S LDYE + + V + A
Sbjct: 275 TDPDEGQNG----EVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQA 330
Query: 508 VDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKN 567
D G ++ ++ ++V+V D NDN P S V+ E PG VA TD DS +N
Sbjct: 331 KDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEEN 390
Query: 568 AEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626
++ L V + + + I+ LDRE D Y V A+D+G P L S ++
Sbjct: 391 GQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQ 450
Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEE----NN 682
VQV+D NDN P+F Q V+ YV EN P + + V+ D D+G NA+++ I E
Sbjct: 451 VQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGM 510
Query: 683 NIF---SIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSA-TATVSLFVMDENDN 738
++F SI ++ G +Y+ SFD E ++F+V+A D G P A ATV++ ++D+NDN
Sbjct: 511 SVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDN 570
Query: 739 APTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFE 793
AP + P + +LP S+ ++ V A D+DDG NA L YSIV GN LF
Sbjct: 571 APAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFR 630
Query: 794 IDPTSGVVSLVGKLTQKH--YGLHRLVVQVNDSGQPS-QSTTTLVHVFVNESVSNATAID 850
+D +G + ++ K + LV++V D GQP ST TLV V+ +V
Sbjct: 631 MDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGG 690
Query: 851 SQIARS-LHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNK 909
S S H ++ G+ S + L++++ + G ++ I ++ ++V+A C+ + K
Sbjct: 691 SGGGGSGEHQRPSRSGGGETSLD-----LTLILIIALGSVSFIFLLAMIVLAVRCQKEKK 745
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.133 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,678,615
Number of Sequences: 37866
Number of extensions: 2185990
Number of successful extensions: 24963
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 344
Number of HSP's successfully gapped in prelim test: 235
Number of HSP's that attempted gapping in prelim test: 9969
Number of HSP's gapped (non-prelim): 4999
length of query: 1072
length of database: 18,247,518
effective HSP length: 113
effective length of query: 959
effective length of database: 13,968,660
effective search space: 13395944940
effective search space used: 13395944940
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.