BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens] (1069 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens] 2124 0.0 gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens] 2105 0.0 gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens] 1957 0.0 gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens] 969 0.0 gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens] 967 0.0 gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens] 697 0.0 gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens] 697 0.0 gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens] 607 e-173 gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens] 607 e-173 gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens] 607 e-173 gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo s... 605 e-173 gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens] 605 e-173 gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens] 605 e-173 gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo ... 605 e-173 gi|190194360 protocadherin 20 [Homo sapiens] 405 e-112 gi|14270499 protocadherin gamma subfamily B, 4 isoform 2 precurs... 336 8e-92 gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precurs... 336 8e-92 gi|14270508 protocadherin gamma subfamily B, 7 isoform 2 precurs... 330 6e-90 gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precurs... 330 6e-90 gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precurs... 322 1e-87 gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs... 322 1e-87 gi|11128029 protocadherin gamma subfamily B, 6 isoform 1 precurs... 321 2e-87 gi|14270502 protocadherin gamma subfamily B, 6 isoform 2 precurs... 321 2e-87 gi|16933557 dachsous 1 precursor [Homo sapiens] 320 6e-87 gi|14270505 protocadherin gamma subfamily B, 5 isoform 2 precurs... 317 3e-86 gi|11128031 protocadherin gamma subfamily B, 5 isoform 1 precurs... 317 3e-86 gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 315 1e-85 gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 315 1e-85 gi|11036656 protocadherin beta 7 precursor [Homo sapiens] 312 9e-85 gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 312 1e-84 >gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens] Length = 1069 Score = 2124 bits (5503), Expect = 0.0 Identities = 1069/1069 (100%), Positives = 1069/1069 (100%) Query: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG Sbjct: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60 Query: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS Sbjct: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120 Query: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY Sbjct: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180 Query: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR Sbjct: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240 Query: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITD 300 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITD Sbjct: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITD 300 Query: 301 VNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL 360 VNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL Sbjct: 301 VNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL 360 Query: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI Sbjct: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420 Query: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ Sbjct: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480 Query: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV Sbjct: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540 Query: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE Sbjct: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600 Query: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM Sbjct: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660 Query: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP Sbjct: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720 Query: 721 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN 780 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN Sbjct: 721 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN 780 Query: 781 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN 840 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN Sbjct: 781 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN 840 Query: 841 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM 900 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM Sbjct: 841 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM 900 Query: 901 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN 960 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN Sbjct: 901 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN 960 Query: 961 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA 1020 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA Sbjct: 961 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA 1020 Query: 1021 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQMRLHPYITVFG 1069 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQMRLHPYITVFG Sbjct: 1021 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQMRLHPYITVFG 1069 >gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens] Length = 1072 Score = 2105 bits (5453), Expect = 0.0 Identities = 1061/1065 (99%), Positives = 1062/1065 (99%) Query: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG Sbjct: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60 Query: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS Sbjct: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120 Query: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY Sbjct: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180 Query: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR Sbjct: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240 Query: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITD 300 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITD Sbjct: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITD 300 Query: 301 VNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL 360 VNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL Sbjct: 301 VNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL 360 Query: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI Sbjct: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420 Query: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ Sbjct: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480 Query: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV Sbjct: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540 Query: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE Sbjct: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600 Query: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM Sbjct: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660 Query: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP Sbjct: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720 Query: 721 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN 780 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN Sbjct: 721 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN 780 Query: 781 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN 840 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN Sbjct: 781 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN 840 Query: 841 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM 900 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM Sbjct: 841 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM 900 Query: 901 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN 960 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN Sbjct: 901 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN 960 Query: 961 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA 1020 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA Sbjct: 961 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA 1020 Query: 1021 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQMRLHPYI 1065 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQ+R P I Sbjct: 1021 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQVRCIPNI 1065 >gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens] Length = 1200 Score = 1957 bits (5071), Expect = 0.0 Identities = 1000/1058 (94%), Positives = 1002/1058 (94%), Gaps = 47/1058 (4%) Query: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG Sbjct: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60 Query: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS Sbjct: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120 Query: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY Sbjct: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180 Query: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR Sbjct: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240 Query: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITD 300 SSVFELQ V D D + Q I+ Sbjct: 241 SSVFELQ--------------------------------VADTPDGEKQPQLIV------ 262 Query: 301 VNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL 360 K VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL Sbjct: 263 ---------KGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL 313 Query: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI Sbjct: 314 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 373 Query: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ Sbjct: 374 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 433 Query: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV Sbjct: 434 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 493 Query: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE Sbjct: 494 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 553 Query: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM Sbjct: 554 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 613 Query: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP Sbjct: 614 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 673 Query: 721 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN 780 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN Sbjct: 674 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN 733 Query: 781 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN 840 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN Sbjct: 734 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN 793 Query: 841 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM 900 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM Sbjct: 794 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM 853 Query: 901 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN 960 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN Sbjct: 854 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN 913 Query: 961 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA 1020 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA Sbjct: 914 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA 973 Query: 1021 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQ 1058 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQ Sbjct: 974 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQ 1011 >gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens] Length = 1237 Score = 969 bits (2504), Expect = 0.0 Identities = 522/1054 (49%), Positives = 706/1054 (66%), Gaps = 65/1054 (6%) Query: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSGEVTFSLESGSEYLKID 78 LLL L+ S A +++ Y++ EE P + IG++A+D G G + + LE G+ YL++D Sbjct: 46 LLLLLAPSPGHATRVV-YKVPEEQPPNTLIGSLAADYGF-PDVGHL-YKLEVGAPYLRVD 102 Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVD-LFEGQVIVLDIN 137 TG++ T+E IDRE L +CQ + C L+FEVS+ Q+ L EGQ+ V DIN Sbjct: 103 GKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDIN 162 Query: 138 DNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRR 197 DNTP F SPV+TL + EN +G+L+ +P A+DRD G NG+ YEL P Sbjct: 163 DNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGP----------- 211 Query: 198 AGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQ 257 +A E +F LQVA+ + EKQ Sbjct: 212 -----------------------------EAQE------------LFGLQVAEDQE-EKQ 229 Query: 258 PQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317 PQLIV G LDRE+ DSY+LT++V+DGG PPR+S A+LRV + D NDN+P+FE+ YEA+L Sbjct: 230 PQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAEL 289 Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREE 377 +ENS G ++Q++A D D G N +IEY F A E VRRLLRLD +G ++V +DRE+ Sbjct: 290 SENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDRED 349 Query: 378 VNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVL 437 ++ LRF+V+A+DRG PK+ +A VV+ +KD NDN P+IEIR IG + +DG+AN++EDV Sbjct: 350 LSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVA 409 Query: 438 VDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEA 497 +T +ALVQVSDRD+GEN VTC V GDVPFQL+ AS+T G +KKKYFL T+TPLDYE Sbjct: 410 EETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASET-GSDSKKKYFLQTTTPLDYEK 468 Query: 498 TREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATV 557 +++ + IVAVDSG+P LSS NSL V+V D NDN P+F QSV EV FPENN PGE +A + Sbjct: 469 VKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEI 528 Query: 558 LATDADSGKNAEIAYSLDS--SVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKG 615 A+DADSG NAE+ YSL+ + G+F I P++G+I V T LDREQ + YE KV A D+G Sbjct: 529 TASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRG 588 Query: 616 IPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMS 675 P LQG+ TV+V V D NDNDPKFM + F V EN+ SPVGMVTV+D DKG NA++ Sbjct: 589 SPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQ 648 Query: 676 LYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDE 735 L +E++N F I+N TGTI S++SFDRE Q+TYTF++KAVDGG PPRSA V++ V+DE Sbjct: 649 LSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDE 708 Query: 736 NDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEID 795 NDNAP +T P N S+ LL P + + V+ V A D D G+NA+L YSI GGNP+ LF+I Sbjct: 709 NDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIG 768 Query: 796 PTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIAR 855 SG ++L ++ ++H+GLHRLVV+V+D G+P + T LVH++VNE+++N T +++ + Sbjct: 769 SHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGH 828 Query: 856 SLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN-KNGYEA 914 SL PL DIAGDP YE SKQR +I+ GVVAG++ V L+I + V+ RYCR + K+GY+A Sbjct: 829 SLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQA 888 Query: 915 GKKDHEDFFTPQQHDKSKKPKKDK-KNKKSKQPLYSSIVTVEASKPNGQRYDSVNEKLSD 973 GKK+ +D + P+ K+ K K K K KS +P+ EA +++ +++ D Sbjct: 889 GKKETKDLYAPKPSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPGD 948 Query: 974 SPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033 SP + + +N PGSPDL RHY+S+SPLP++QL PQSP+A KKHQ VQDLPPANTFVG Sbjct: 949 SPRI--HLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGT 1006 Query: 1034 GDNISIGSDHCSEYSCQTN-NKYSKQMRLHPYIT 1066 GD S GS+ S+YS +TN KY + H +T Sbjct: 1007 GDTTSTGSEQYSDYSYRTNPPKYPSKQLPHRRVT 1040 >gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens] Length = 1060 Score = 967 bits (2500), Expect = 0.0 Identities = 523/1048 (49%), Positives = 706/1048 (67%), Gaps = 66/1048 (6%) Query: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSGEVTFSLESGSEYLKID 78 LLL L+ S A +++ Y++ EE P + IG++A+D G G + + LE G+ YL++D Sbjct: 46 LLLLLAPSPGHATRVV-YKVPEEQPPNTLIGSLAADYGF-PDVGHL-YKLEVGAPYLRVD 102 Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVD-LFEGQVIVLDIN 137 TG++ T+E IDRE L +CQ + C L+FEVS+ Q+ L EGQ+ V DIN Sbjct: 103 GKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDIN 162 Query: 138 DNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRR 197 DNTP F SPV+TL + EN +G+L+ +P A+DRD G NG+ YEL P Sbjct: 163 DNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGP----------- 211 Query: 198 AGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQ 257 +A E +F LQVA+ + EKQ Sbjct: 212 -----------------------------EAQE------------LFGLQVAEDQE-EKQ 229 Query: 258 PQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317 PQLIV G LDRE+ DSY+LT++V+DGG PPR+S A+LRV + D NDN+P+FE+ YEA+L Sbjct: 230 PQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAEL 289 Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREE 377 +ENS G ++Q++A D D G N +IEY F A E VRRLLRLD +G ++V +DRE+ Sbjct: 290 SENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDRED 349 Query: 378 VNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVL 437 ++ LRF+V+A+DRG PK+ +A VV+ +KD NDN P+IEIR IG + +DG+AN++EDV Sbjct: 350 LSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVA 409 Query: 438 VDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEA 497 +T +ALVQVSDRD+GEN VTC V GDVPFQL+ AS+T G +KKKYFL T+TPLDYE Sbjct: 410 EETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASET-GSDSKKKYFLQTTTPLDYEK 468 Query: 498 TREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATV 557 +++ + IVAVDSG+P LSS NSL V+V D NDN P+F QSV EV FPENN PGE +A + Sbjct: 469 VKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEI 528 Query: 558 LATDADSGKNAEIAYSLDS--SVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKG 615 A+DADSG NAE+ YSL+ + G+F I P++G+I V T LDREQ + YE KV A D+G Sbjct: 529 TASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRG 588 Query: 616 IPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMS 675 P LQG+ TV+V V D NDNDPKFM + F V EN+ SPVGMVTV+D DKG NA++ Sbjct: 589 SPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQ 648 Query: 676 LYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDE 735 L +E++N F I+N TGTI S++SFDRE Q+TYTF++KAVDGG PPRSA V++ V+DE Sbjct: 649 LSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDE 708 Query: 736 NDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEID 795 NDNAP +T P N S+ LL P + + V+ V A D D G+NA+L YSI GGNP+ LF+I Sbjct: 709 NDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIG 768 Query: 796 PTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIAR 855 SG ++L ++ ++H+GLHRLVV+V+D G+P + T LVH++VNE+++N T +++ + Sbjct: 769 SHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGH 828 Query: 856 SLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN-KNGYEA 914 SL PL DIAGDP YE SKQR +I+ GVVAG++ V L+I + V+ RYCR + K+GY+A Sbjct: 829 SLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQA 888 Query: 915 GKKDHEDFFTPQQHDKSKKPKKDK-KNKKSKQPLYSSIVTVEASKPNGQRYDSVNEKLSD 973 GKK+ +D + P+ K+ K K K K KS +P+ EA +++ +++ D Sbjct: 889 GKKETKDLYAPKPSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPGD 948 Query: 974 SPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033 SP + + +N PGSPDL RHY+S+SPLP++QL PQSP+A KKHQ VQDLPPANTFVG Sbjct: 949 SPRI--HLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGT 1006 Query: 1034 GDNISIGSDHCSEYSCQTN-NKY-SKQM 1059 GD S GS+ S+YS +TN KY SKQ+ Sbjct: 1007 GDTTSTGSEQYSDYSYRTNPPKYPSKQV 1034 >gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens] Length = 1203 Score = 697 bits (1799), Expect = 0.0 Identities = 427/1078 (39%), Positives = 606/1078 (56%), Gaps = 98/1078 (9%) Query: 11 RGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-----VTG-SGEV 64 R + L L+ L L A A++L+ Y + EE P +V IGN+ DL I TG S + Sbjct: 4 RDFYLLAALIACLRLDSAIAQELI-YTIREELPENVPIGNIPKDLNISHINAATGTSASL 62 Query: 65 TFSLES---GSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQ 121 + L S + +K+ + TGE+ T+ RIDREKL +ENECF + EV ++ Sbjct: 63 VYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVIL--PN 120 Query: 122 SWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYE 181 + L + ++IV D NDN P FPSPV+ +++ EN + + + +P+ATD Sbjct: 121 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATD------------ 168 Query: 182 LLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRS 241 P G NG + + G Sbjct: 169 -------------------------PDTGFNGV---------QHYELLNG---------Q 185 Query: 242 SVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDV 301 SVF L + +TP+GEK PQLIV+ LDREQ+D+Y + ++V DGG P +SS AIL+V ++DV Sbjct: 186 SVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDV 245 Query: 302 NDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGA-ATESVRRLLRL 360 NDN P F++ E + EN+ GT ++QL A D D+G N +I Y+FGA + +RL L Sbjct: 246 NDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFAL 305 Query: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420 + T+G ++V +DREE + TV+A D P +ATV +N+ D NDN P+I++R I Sbjct: 306 NNTTGLITVQRSLDREETAIHKVTVLASDGSSTPA--RATVTINVTDVNDNPPNIDLRYI 363 Query: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480 I +G ++E V+T IAL+ VSD+D NG V C + +VPF LK D + Sbjct: 364 --ISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQ--- 418 Query: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540 Y L TS+ LDYE T+EF+ IVA DSG PSL+ + VK+ D NDNPP+F Q V+ Sbjct: 419 ----YLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVI 474 Query: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600 E+ ENN G + T+ ATD DSGKNA+I Y L + F +D +G + + V DRE Sbjct: 475 ELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDRE 533 Query: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660 + +R+ F V A+D G P LQ VIV V D+NDN PKF + F F+V ENL S VG+ Sbjct: 534 EQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGV 593 Query: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720 +TV DAD G N ++L I +N+ F ++ +G I S +SFDRE Q++YTF VKA DGG P Sbjct: 594 ITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQP 653 Query: 721 PRSATATVSLFVMDENDNAPTV-TLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADL 779 PRS+TA V++ VMD NDN+P V + P N S+ L+P S+ +VVA V A D D G+NA+L Sbjct: 654 PRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAEL 713 Query: 780 NYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVF 838 Y+IV GN LF IDP +G ++L K GLHRLVV ++D G P S T LV ++ Sbjct: 714 KYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLY 773 Query: 839 VNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIV 898 VN++ NA+ I I R++ PL ++I ++ L+I+I ++AG M VI++I + Sbjct: 774 VNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVT 833 Query: 899 VMARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASK 958 V+ R CR ++ K ++ +P Q +K K KK KK K K L + VT+E SK Sbjct: 834 VLVR-CRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLL-NFVTIEESK 891 Query: 959 PNGQRYDSVNEKLS-----DSPSMGRY-----RSVNGGPGSPDLARHYKSSSPLPTVQLH 1008 P+ ++ +N +S + S+GR+ P SPDLA+HYKS+SP P L Sbjct: 892 PDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLK 951 Query: 1009 PQSPTAGKKHQAVQDLPPANTFVGAGDNI----SIGSDHCSEYSCQTNNKYSKQMRLH 1062 P +P + KKH +Q+LP NTFVG D + S SDH S C + + + LH Sbjct: 952 PDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLH 1009 >gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens] Length = 1237 Score = 697 bits (1799), Expect = 0.0 Identities = 427/1078 (39%), Positives = 606/1078 (56%), Gaps = 98/1078 (9%) Query: 11 RGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-----VTG-SGEV 64 R + L L+ L L A A++L+ Y + EE P +V IGN+ DL I TG S + Sbjct: 4 RDFYLLAALIACLRLDSAIAQELI-YTIREELPENVPIGNIPKDLNISHINAATGTSASL 62 Query: 65 TFSLES---GSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQ 121 + L S + +K+ + TGE+ T+ RIDREKL +ENECF + EV ++ Sbjct: 63 VYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVIL--PN 120 Query: 122 SWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYE 181 + L + ++IV D NDN P FPSPV+ +++ EN + + + +P+ATD Sbjct: 121 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATD------------ 168 Query: 182 LLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRS 241 P G NG + + G Sbjct: 169 -------------------------PDTGFNGV---------QHYELLNG---------Q 185 Query: 242 SVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDV 301 SVF L + +TP+GEK PQLIV+ LDREQ+D+Y + ++V DGG P +SS AIL+V ++DV Sbjct: 186 SVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDV 245 Query: 302 NDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGA-ATESVRRLLRL 360 NDN P F++ E + EN+ GT ++QL A D D+G N +I Y+FGA + +RL L Sbjct: 246 NDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFAL 305 Query: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420 + T+G ++V +DREE + TV+A D P +ATV +N+ D NDN P+I++R I Sbjct: 306 NNTTGLITVQRSLDREETAIHKVTVLASDGSSTPA--RATVTINVTDVNDNPPNIDLRYI 363 Query: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480 I +G ++E V+T IAL+ VSD+D NG V C + +VPF LK D + Sbjct: 364 --ISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQ--- 418 Query: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540 Y L TS+ LDYE T+EF+ IVA DSG PSL+ + VK+ D NDNPP+F Q V+ Sbjct: 419 ----YLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVI 474 Query: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600 E+ ENN G + T+ ATD DSGKNA+I Y L + F +D +G + + V DRE Sbjct: 475 ELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDRE 533 Query: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660 + +R+ F V A+D G P LQ VIV V D+NDN PKF + F F+V ENL S VG+ Sbjct: 534 EQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGV 593 Query: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720 +TV DAD G N ++L I +N+ F ++ +G I S +SFDRE Q++YTF VKA DGG P Sbjct: 594 ITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQP 653 Query: 721 PRSATATVSLFVMDENDNAPTV-TLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADL 779 PRS+TA V++ VMD NDN+P V + P N S+ L+P S+ +VVA V A D D G+NA+L Sbjct: 654 PRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAEL 713 Query: 780 NYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVF 838 Y+IV GN LF IDP +G ++L K GLHRLVV ++D G P S T LV ++ Sbjct: 714 KYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLY 773 Query: 839 VNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIV 898 VN++ NA+ I I R++ PL ++I ++ L+I+I ++AG M VI++I + Sbjct: 774 VNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVT 833 Query: 899 VMARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASK 958 V+ R CR ++ K ++ +P Q +K K KK KK K K L + VT+E SK Sbjct: 834 VLVR-CRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLL-NFVTIEESK 891 Query: 959 PNGQRYDSVNEKLS-----DSPSMGRY-----RSVNGGPGSPDLARHYKSSSPLPTVQLH 1008 P+ ++ +N +S + S+GR+ P SPDLA+HYKS+SP P L Sbjct: 892 PDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLK 951 Query: 1009 PQSPTAGKKHQAVQDLPPANTFVGAGDNI----SIGSDHCSEYSCQTNNKYSKQMRLH 1062 P +P + KKH +Q+LP NTFVG D + S SDH S C + + + LH Sbjct: 952 PDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLH 1009 >gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens] Length = 1340 Score = 607 bits (1564), Expect = e-173 Identities = 383/1033 (37%), Positives = 571/1033 (55%), Gaps = 95/1033 (9%) Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87 Y + EE P +V IGN+ DL + +T + + ++G ++I+ TGE+ T+ Sbjct: 60 YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 119 Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147 RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V Sbjct: 120 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 175 Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207 + +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P Sbjct: 176 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 225 Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267 G + +L V D E++ ++K Sbjct: 226 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 250 Query: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327 ++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT + Sbjct: 251 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 300 Query: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386 QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+ Sbjct: 301 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 360 Query: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446 A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+ Sbjct: 361 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 416 Query: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506 V+D+D NG VTC ++PF+L+P + + L + LDYE+T+E+ + ++ Sbjct: 417 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLENAAYLDYESTKEYAIKLL 469 Query: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566 A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V ATDADSG Sbjct: 470 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGP 529 Query: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626 NAEI Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV Sbjct: 530 NAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 589 Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686 V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+ Sbjct: 590 VSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 649 Query: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745 I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P Sbjct: 650 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 709 Query: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805 N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+ Sbjct: 710 YNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 769 Query: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864 K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S+ P+T + Sbjct: 770 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPN 829 Query: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924 + + I++ VAG +TV+++I I + R CR + ++ T Sbjct: 830 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNMQNSEWAT 888 Query: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977 P ++ K KK KK P L ++VT+E +K + D L + +M Sbjct: 889 PNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 948 Query: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033 G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A Sbjct: 949 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFV-A 1006 Query: 1034 GDNISIGSDHCSE 1046 D+IS S S+ Sbjct: 1007 CDSISNCSSSSSD 1019 >gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens] Length = 1048 Score = 607 bits (1564), Expect = e-173 Identities = 383/1033 (37%), Positives = 571/1033 (55%), Gaps = 95/1033 (9%) Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87 Y + EE P +V IGN+ DL + +T + + ++G ++I+ TGE+ T+ Sbjct: 60 YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 119 Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147 RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V Sbjct: 120 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 175 Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207 + +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P Sbjct: 176 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 225 Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267 G + +L V D E++ ++K Sbjct: 226 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 250 Query: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327 ++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT + Sbjct: 251 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 300 Query: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386 QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+ Sbjct: 301 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 360 Query: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446 A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+ Sbjct: 361 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 416 Query: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506 V+D+D NG VTC ++PF+L+P + + L + LDYE+T+E+ + ++ Sbjct: 417 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLENAAYLDYESTKEYAIKLL 469 Query: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566 A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V ATDADSG Sbjct: 470 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGP 529 Query: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626 NAEI Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV Sbjct: 530 NAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 589 Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686 V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+ Sbjct: 590 VSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 649 Query: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745 I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P Sbjct: 650 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 709 Query: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805 N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+ Sbjct: 710 YNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 769 Query: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864 K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S+ P+T + Sbjct: 770 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPN 829 Query: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924 + + I++ VAG +TV+++I I + R CR + ++ T Sbjct: 830 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNMQNSEWAT 888 Query: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977 P ++ K KK KK P L ++VT+E +K + D L + +M Sbjct: 889 PNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 948 Query: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033 G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A Sbjct: 949 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFV-A 1006 Query: 1034 GDNISIGSDHCSE 1046 D+IS S S+ Sbjct: 1007 CDSISNCSSSSSD 1019 >gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens] Length = 1037 Score = 607 bits (1564), Expect = e-173 Identities = 383/1033 (37%), Positives = 571/1033 (55%), Gaps = 95/1033 (9%) Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87 Y + EE P +V IGN+ DL + +T + + ++G ++I+ TGE+ T+ Sbjct: 49 YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 108 Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147 RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V Sbjct: 109 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 164 Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207 + +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P Sbjct: 165 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 214 Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267 G + +L V D E++ ++K Sbjct: 215 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 239 Query: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327 ++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT + Sbjct: 240 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 289 Query: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386 QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+ Sbjct: 290 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 349 Query: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446 A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+ Sbjct: 350 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 405 Query: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506 V+D+D NG VTC ++PF+L+P + + L + LDYE+T+E+ + ++ Sbjct: 406 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLENAAYLDYESTKEYAIKLL 458 Query: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566 A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V ATDADSG Sbjct: 459 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGP 518 Query: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626 NAEI Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV Sbjct: 519 NAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 578 Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686 V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+ Sbjct: 579 VSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 638 Query: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745 I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P Sbjct: 639 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 698 Query: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805 N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+ Sbjct: 699 YNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 758 Query: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864 K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S+ P+T + Sbjct: 759 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPN 818 Query: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924 + + I++ VAG +TV+++I I + R CR + ++ T Sbjct: 819 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNMQNSEWAT 877 Query: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977 P ++ K KK KK P L ++VT+E +K + D L + +M Sbjct: 878 PNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 937 Query: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033 G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A Sbjct: 938 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFV-A 995 Query: 1034 GDNISIGSDHCSE 1046 D+IS S S+ Sbjct: 996 CDSISNCSSSSSD 1008 >gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo sapiens] Length = 1021 Score = 605 bits (1560), Expect = e-173 Identities = 382/1033 (36%), Positives = 570/1033 (55%), Gaps = 95/1033 (9%) Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87 Y + EE P +V IG++ DL + +T + + ++G ++I+ TGE+ T+ Sbjct: 28 YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87 Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147 RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V Sbjct: 88 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143 Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207 + +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P Sbjct: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 193 Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267 G + +L V D E++ ++K Sbjct: 194 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 218 Query: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327 ++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT + Sbjct: 219 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 268 Query: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386 QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+ Sbjct: 269 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 328 Query: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446 A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+ Sbjct: 329 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 384 Query: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506 V+D+D NG VTC ++PF+L+P + + L T+ LDYE+T+E+ + ++ Sbjct: 385 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETAAYLDYESTKEYAIKLL 437 Query: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566 A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V A DADSG Sbjct: 438 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGP 497 Query: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626 NA+I Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV Sbjct: 498 NAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 557 Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686 V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+ Sbjct: 558 VSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 617 Query: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745 I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P Sbjct: 618 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 677 Query: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805 N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+ Sbjct: 678 SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 737 Query: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864 K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S P+T + Sbjct: 738 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPN 797 Query: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924 + + I++ VAG +TV+++I I + R CR K + ++ T Sbjct: 798 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNKQNSEWAT 856 Query: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977 P ++ K KK KK P L + VT+E +K + D L + +M Sbjct: 857 PNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 916 Query: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033 G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A Sbjct: 917 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFV-A 974 Query: 1034 GDNISIGSDHCSE 1046 D+IS S S+ Sbjct: 975 CDSISKCSSSSSD 987 >gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens] Length = 1337 Score = 605 bits (1560), Expect = e-173 Identities = 382/1033 (36%), Positives = 570/1033 (55%), Gaps = 95/1033 (9%) Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87 Y + EE P +V IG++ DL + +T + + ++G ++I+ TGE+ T+ Sbjct: 28 YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87 Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147 RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V Sbjct: 88 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143 Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207 + +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P Sbjct: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 193 Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267 G + +L V D E++ ++K Sbjct: 194 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 218 Query: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327 ++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT + Sbjct: 219 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 268 Query: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386 QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+ Sbjct: 269 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 328 Query: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446 A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+ Sbjct: 329 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 384 Query: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506 V+D+D NG VTC ++PF+L+P + + L T+ LDYE+T+E+ + ++ Sbjct: 385 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETAAYLDYESTKEYAIKLL 437 Query: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566 A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V A DADSG Sbjct: 438 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGP 497 Query: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626 NA+I Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV Sbjct: 498 NAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 557 Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686 V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+ Sbjct: 558 VSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 617 Query: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745 I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P Sbjct: 618 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 677 Query: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805 N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+ Sbjct: 678 SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 737 Query: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864 K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S P+T + Sbjct: 738 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPN 797 Query: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924 + + I++ VAG +TV+++I I + R CR K + ++ T Sbjct: 798 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNKQNSEWAT 856 Query: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977 P ++ K KK KK P L + VT+E +K + D L + +M Sbjct: 857 PNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 916 Query: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033 G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A Sbjct: 917 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFV-A 974 Query: 1034 GDNISIGSDHCSE 1046 D+IS S S+ Sbjct: 975 CDSISKCSSSSSD 987 >gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens] Length = 1347 Score = 605 bits (1560), Expect = e-173 Identities = 382/1033 (36%), Positives = 570/1033 (55%), Gaps = 95/1033 (9%) Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87 Y + EE P +V IG++ DL + +T + + ++G ++I+ TGE+ T+ Sbjct: 28 YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87 Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147 RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V Sbjct: 88 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143 Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207 + +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P Sbjct: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 193 Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267 G + +L V D E++ ++K Sbjct: 194 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 218 Query: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327 ++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT + Sbjct: 219 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 268 Query: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386 QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+ Sbjct: 269 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 328 Query: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446 A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+ Sbjct: 329 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 384 Query: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506 V+D+D NG VTC ++PF+L+P + + L T+ LDYE+T+E+ + ++ Sbjct: 385 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETAAYLDYESTKEYAIKLL 437 Query: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566 A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V A DADSG Sbjct: 438 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGP 497 Query: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626 NA+I Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV Sbjct: 498 NAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 557 Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686 V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+ Sbjct: 558 VSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 617 Query: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745 I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P Sbjct: 618 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 677 Query: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805 N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+ Sbjct: 678 SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 737 Query: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864 K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S P+T + Sbjct: 738 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPN 797 Query: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924 + + I++ VAG +TV+++I I + R CR K + ++ T Sbjct: 798 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNKQNSEWAT 856 Query: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977 P ++ K KK KK P L + VT+E +K + D L + +M Sbjct: 857 PNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 916 Query: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033 G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A Sbjct: 917 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFV-A 974 Query: 1034 GDNISIGSDHCSE 1046 D+IS S S+ Sbjct: 975 CDSISKCSSSSSD 987 >gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo sapiens] Length = 1025 Score = 605 bits (1560), Expect = e-173 Identities = 382/1033 (36%), Positives = 570/1033 (55%), Gaps = 95/1033 (9%) Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87 Y + EE P +V IG++ DL + +T + + ++G ++I+ TGE+ T+ Sbjct: 28 YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87 Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147 RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V Sbjct: 88 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143 Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207 + +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P Sbjct: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 193 Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267 G + +L V D E++ ++K Sbjct: 194 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 218 Query: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327 ++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT + Sbjct: 219 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 268 Query: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386 QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+ Sbjct: 269 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 328 Query: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446 A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+ Sbjct: 329 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 384 Query: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506 V+D+D NG VTC ++PF+L+P + + L T+ LDYE+T+E+ + ++ Sbjct: 385 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETAAYLDYESTKEYAIKLL 437 Query: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566 A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V A DADSG Sbjct: 438 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGP 497 Query: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626 NA+I Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV Sbjct: 498 NAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 557 Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686 V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+ Sbjct: 558 VSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 617 Query: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745 I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P Sbjct: 618 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 677 Query: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805 N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+ Sbjct: 678 SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 737 Query: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864 K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S P+T + Sbjct: 738 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPN 797 Query: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924 + + I++ VAG +TV+++I I + R CR K + ++ T Sbjct: 798 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNKQNSEWAT 856 Query: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977 P ++ K KK KK P L + VT+E +K + D L + +M Sbjct: 857 PNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 916 Query: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033 G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A Sbjct: 917 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFV-A 974 Query: 1034 GDNISIGSDHCSE 1046 D+IS S S+ Sbjct: 975 CDSISKCSSSSSD 987 >gi|190194360 protocadherin 20 [Homo sapiens] Length = 951 Score = 405 bits (1041), Expect = e-112 Identities = 295/920 (32%), Positives = 451/920 (49%), Gaps = 112/920 (12%) Query: 26 SLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSG-------------------EVTF 66 S + A +LL Y L E PA V IG++A DL ++ S ++F Sbjct: 61 SYSRATELL-YSLNEGLPAGVLIGSLAEDLRLLPRSAGRPDPQSQLPERTGAEWNPPLSF 119 Query: 67 SLES---GSEYLKIDNLTGELSTSERRIDREKL------------PQCQMIFDENECFLD 111 SL S +Y+ +DN +GEL TS + IDRE L + C L Sbjct: 120 SLASRGLSGQYVTLDNRSGELHTSAQEIDREALCVEGGGGTAWSGSVSISSSPSDSCLLL 179 Query: 112 FEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRD 171 +V V+ Q + + ++ + DINDN P FP +++ V EN PV T Sbjct: 180 LDVLVL--PQEYFRFVKVKIAIRDINDNAPQFPVSQISVWVPENAPVNT----------- 226 Query: 172 FGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEG 231 R A P G NG + R LD Sbjct: 227 -------------------------RLAIEHPAVDPDVGINGVQ------TYRLLDYH-- 253 Query: 232 GGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQ 291 +F L V + +GE+ P LIV GALDRE +D Y + DGG PP Sbjct: 254 ----------GMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGGSPPLLGS 303 Query: 292 AILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAAT 351 A L + I+D+NDN P F S + N+ GTPI ++A D D+G N QI Y + Sbjct: 304 ATLTIGISDINDNCPLFTDSQINVTVYGNATVGTPIAAVQAVDKDLGTNAQITYSYSQKV 363 Query: 352 -ESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDEND 410 ++ + L LDE +G + + +I + + T++A G P T +++I Sbjct: 364 PQASKDLFHLDENTGVIKLFSKIGGSVLESHKLTILANGPGCIPAV--ITALVSIIKVIF 421 Query: 411 NVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQL 470 P I R I DGV + E V+TPIA + RD V C + G+ PF+L Sbjct: 422 RPPEIVPRYIANEI--DGVVYLKELEPVNTPIAFFTI--RDPEGKYKVNCYLDGEGPFRL 477 Query: 471 KPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTND 530 P + Y L T+ P+DYE + + V +VA +S + V++ D ND Sbjct: 478 SPYKPYNNE-----YLLETTKPMDYELQQFYEVAVVAWNS--EGFHVKRVIKVQLLDDND 530 Query: 531 NPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGD 590 N P+F Q ++E+ ENN P + + ATDADS + +++Y L F++D +G Sbjct: 531 NAPIFLQPLIELTIEENNSPNAFLTKLYATDADSEERGQVSYFLGPDAPSYFSLDSVTGI 590 Query: 591 ILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKE 650 + V+T LDRE+ ++Y + V A D G P + TV + V DKNDN P+F+ F+F+V E Sbjct: 591 LTVSTQLDREEKEKYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINKDFSFFVPE 650 Query: 651 NLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTF 710 N +G+++V DAD GRN ++L + ++IF I+ G + + +S DRE Q++YT Sbjct: 651 NFPGYGEIGVISVTDADAGRNGWVALSVVNQSDIFVIDTGKGMLRAKVSLDREQQSSYTL 710 Query: 711 RVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPK-NISYTLLPPSSNVRTVVATVLAT 769 V+AVDGG+P S+TA +++ ++D NDN P V P+ N+SY L+ PS+ + V V A Sbjct: 711 WVEAVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPVTEVYAV 770 Query: 770 DSDDGINADLNYSIVG--GNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP 827 D D G+NA + YSI+G G + F IDP +G ++L L Q YGLHRL+V+V+D G P Sbjct: 771 DKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYP 830 Query: 828 SQ-STTTLVHVFVNESVSNATAIDSQIARSLHIPLTQ---DIAGDPSYEISKQRLSIVIG 883 +T +V++FVN++VSN + I+S + + I + + I+ +P++ + + Sbjct: 831 EPLHSTVMVNLFVNDTVSNESYIESLLRKEPEINIEEKEPQISIEPTHRKVESVSCMPTL 890 Query: 884 VVAGIMTVILIILIVVMARY 903 V ++++ I L+ M Y Sbjct: 891 VALSVISLGSITLVTGMGIY 910 >gi|14270499 protocadherin gamma subfamily B, 4 isoform 2 precursor [Homo sapiens] Length = 803 Score = 336 bits (861), Expect = 8e-92 Identities = 230/731 (31%), Positives = 349/731 (47%), Gaps = 101/731 (13%) Query: 20 LLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYLKID 78 L LSL A + +RYR+ EE P +GN+A+DLG V + S Y + Sbjct: 19 LFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVS 78 Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDIND 138 +GEL S R +DRE++ + C L+FE P ++ + V + DIND Sbjct: 79 AESGELLVSSR-LDREEI-----CGKKPACALEFEAVAENP----LNFYHVNVEIEDIND 128 Query: 139 NTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRA 198 +TP F L + E+ GT ++L +A D D G N ++ Y+L Sbjct: 129 HTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQL---------------- 172 Query: 199 GAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQP 258 +P S+ + +D G K P Sbjct: 173 -------------------------------------SPSDHFSLINKEKSD---GSKYP 192 Query: 259 QLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLA 318 ++++K LDRE++ SY LTL D G PP SS A + VL+TD NDN+P F + VY L+ Sbjct: 193 EMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDVYRVSLS 252 Query: 319 ENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEV 378 EN PGT +LQ+ A D D GVN +I + F A++ + L+ +G ++VL+ +D EEV Sbjct: 253 ENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQ--FDLNSNTGEITVLNTLDFEEV 310 Query: 379 NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLV 438 + + ARD G + TV + + DENDN P + + + + + ED + Sbjct: 311 KEYSIVLEARDGG--GMIAQCTVEVEVIDENDNAPEVIFQSLPNL--------IMEDAEL 360 Query: 439 DTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEAT 498 T IAL++V D+D NG VTC + GDVPF++ +S + Y L T LD E Sbjct: 361 GTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSS-------RNTYKLVTDAVLDREQN 413 Query: 499 REFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVL 558 E+N+ + A D G P LSS++S+ + +GD NDN P+F QS V+ ENN PG ++ V Sbjct: 414 PEYNITVTATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVR 473 Query: 559 ATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAK 612 A+D D G N +++Y + +S + +I +SG + D EQ +E + A+ Sbjct: 474 ASDPDLGPNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQAR 533 Query: 613 DKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNSPVGMVTVMD 665 D+G P L + ++ V V D+NDN P+ + V +P V V +D Sbjct: 534 DQGSPALSANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVTKVVAVD 593 Query: 666 ADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRS 723 AD G NA +S ++ + + +FS+ TG + + + V DGG PP S Sbjct: 594 ADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLS 653 Query: 724 ATATVSLFVMD 734 ATAT+ L D Sbjct: 654 ATATLHLVFAD 664 Score = 228 bits (582), Expect = 2e-59 Identities = 175/662 (26%), Positives = 305/662 (46%), Gaps = 58/662 (8%) Query: 259 QLIVKGALDREQRDSYE--LTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEAD 316 +L+V LDRE+ + L + P + + V I D+ND++P+F ++ +E Sbjct: 83 ELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHV-NVEIEDINDHTPKFTQNSFELQ 141 Query: 317 LAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW----LSVLHR 372 ++E++ PGT + A D D+G N Y + L+ +++ G + + Sbjct: 142 ISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHF--SLINKEKSDGSKYPEMVLKTP 199 Query: 373 IDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANV 432 +DRE+ T+ A D G PP + A + + + D NDN P + + R+ L Sbjct: 200 LDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFS-QDVYRVSL------- 251 Query: 433 AEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASD-TEGDQNKKKYFLHTST 491 +E+V T + V +D+D+G N +T F AS T+ D N + Sbjct: 252 SENVYPGTTVLQVTATDQDEGVNAEIT--------FSFSEASQITQFDLNSNTGEITVLN 303 Query: 492 PLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPP-MFGQSVVEVYFPENNIP 550 LD+E +E+++V+ A D G + + ++ V+V D NDN P + QS+ + + + Sbjct: 304 TLDFEEVKEYSIVLEARDGGG--MIAQCTVEVEVIDENDNAPEVIFQSLPNLIMEDAEL- 360 Query: 551 GERVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFKV 609 G +A + D DS N E+ L+ V I ++ ++ + VLDREQ Y V Sbjct: 361 GTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITV 420 Query: 610 NAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKG 669 A D+G P L S+++ + + D NDN P F Q + +V EN P + + V D D G Sbjct: 421 TATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVRASDPDLG 480 Query: 670 RNAEMSLYI-------EENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPR 722 N ++S I E ++ SI ++G +++ +FD E + ++A D G P Sbjct: 481 PNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQARDQGSPAL 540 Query: 723 SATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGINA 777 SA ++ + V D NDNAP V P + + ++P ++ +V V+A D+D G NA Sbjct: 541 SANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVTKVVAVDADSGHNA 600 Query: 778 DLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837 L+Y ++ + LF + +G V L + RL+V V D GQP S T +H+ Sbjct: 601 WLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLSATATLHL 660 Query: 838 FVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILI 897 +S+ + DI P + L + V +++V+ ++ + Sbjct: 661 VFADSLQE---------------VLPDITDRPDPSDLQAELQFYLVVALALISVLFLVAM 705 Query: 898 VV 899 ++ Sbjct: 706 IL 707 Score = 110 bits (274), Expect = 9e-24 Identities = 77/274 (28%), Positives = 134/274 (48%), Gaps = 19/274 (6%) Query: 576 SSVMGIFAIDPDSGDILVNTVLDREQ------TDRYEFKVNAKDKGIPVLQGSTTVIVQV 629 SS F + +SG++LV++ LDRE+ EF+ A++ V V++ Sbjct: 69 SSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENP-----LNFYHVNVEI 123 Query: 630 ADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIFSI 687 D ND+ PKF Q+ F + E+ QP + + + DAD G N + + ++ ++ + Sbjct: 124 EDINDHTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINK 183 Query: 688 ENDTGTIYSTM----SFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVT 743 E G+ Y M DRE Q +Y + A+D G PP S+TA + + V D NDNAP + Sbjct: 184 EKSDGSKYPEMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFS 243 Query: 744 LPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSL 803 +++ L + T V V ATD D+G+NA++ +S + F+++ +G +++ Sbjct: 244 --QDVYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEITV 301 Query: 804 VGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837 + L + + +V++ D G T V V Sbjct: 302 LNTLDFEEVKEYSIVLEARDGGGMIAQCTVEVEV 335 >gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precursor [Homo sapiens] Length = 923 Score = 336 bits (861), Expect = 8e-92 Identities = 230/731 (31%), Positives = 349/731 (47%), Gaps = 101/731 (13%) Query: 20 LLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYLKID 78 L LSL A + +RYR+ EE P +GN+A+DLG V + S Y + Sbjct: 19 LFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVS 78 Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDIND 138 +GEL S R +DRE++ + C L+FE P ++ + V + DIND Sbjct: 79 AESGELLVSSR-LDREEI-----CGKKPACALEFEAVAENP----LNFYHVNVEIEDIND 128 Query: 139 NTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRA 198 +TP F L + E+ GT ++L +A D D G N ++ Y+L Sbjct: 129 HTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQL---------------- 172 Query: 199 GAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQP 258 +P S+ + +D G K P Sbjct: 173 -------------------------------------SPSDHFSLINKEKSD---GSKYP 192 Query: 259 QLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLA 318 ++++K LDRE++ SY LTL D G PP SS A + VL+TD NDN+P F + VY L+ Sbjct: 193 EMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDVYRVSLS 252 Query: 319 ENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEV 378 EN PGT +LQ+ A D D GVN +I + F A++ + L+ +G ++VL+ +D EEV Sbjct: 253 ENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQ--FDLNSNTGEITVLNTLDFEEV 310 Query: 379 NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLV 438 + + ARD G + TV + + DENDN P + + + + + ED + Sbjct: 311 KEYSIVLEARDGG--GMIAQCTVEVEVIDENDNAPEVIFQSLPNL--------IMEDAEL 360 Query: 439 DTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEAT 498 T IAL++V D+D NG VTC + GDVPF++ +S + Y L T LD E Sbjct: 361 GTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSS-------RNTYKLVTDAVLDREQN 413 Query: 499 REFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVL 558 E+N+ + A D G P LSS++S+ + +GD NDN P+F QS V+ ENN PG ++ V Sbjct: 414 PEYNITVTATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVR 473 Query: 559 ATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAK 612 A+D D G N +++Y + +S + +I +SG + D EQ +E + A+ Sbjct: 474 ASDPDLGPNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQAR 533 Query: 613 DKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNSPVGMVTVMD 665 D+G P L + ++ V V D+NDN P+ + V +P V V +D Sbjct: 534 DQGSPALSANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVTKVVAVD 593 Query: 666 ADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRS 723 AD G NA +S ++ + + +FS+ TG + + + V DGG PP S Sbjct: 594 ADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLS 653 Query: 724 ATATVSLFVMD 734 ATAT+ L D Sbjct: 654 ATATLHLVFAD 664 Score = 228 bits (582), Expect = 2e-59 Identities = 175/662 (26%), Positives = 305/662 (46%), Gaps = 58/662 (8%) Query: 259 QLIVKGALDREQRDSYE--LTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEAD 316 +L+V LDRE+ + L + P + + V I D+ND++P+F ++ +E Sbjct: 83 ELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHV-NVEIEDINDHTPKFTQNSFELQ 141 Query: 317 LAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW----LSVLHR 372 ++E++ PGT + A D D+G N Y + L+ +++ G + + Sbjct: 142 ISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHF--SLINKEKSDGSKYPEMVLKTP 199 Query: 373 IDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANV 432 +DRE+ T+ A D G PP + A + + + D NDN P + + R+ L Sbjct: 200 LDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFS-QDVYRVSL------- 251 Query: 433 AEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASD-TEGDQNKKKYFLHTST 491 +E+V T + V +D+D+G N +T F AS T+ D N + Sbjct: 252 SENVYPGTTVLQVTATDQDEGVNAEIT--------FSFSEASQITQFDLNSNTGEITVLN 303 Query: 492 PLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPP-MFGQSVVEVYFPENNIP 550 LD+E +E+++V+ A D G + + ++ V+V D NDN P + QS+ + + + Sbjct: 304 TLDFEEVKEYSIVLEARDGGG--MIAQCTVEVEVIDENDNAPEVIFQSLPNLIMEDAEL- 360 Query: 551 GERVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFKV 609 G +A + D DS N E+ L+ V I ++ ++ + VLDREQ Y V Sbjct: 361 GTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITV 420 Query: 610 NAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKG 669 A D+G P L S+++ + + D NDN P F Q + +V EN P + + V D D G Sbjct: 421 TATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVRASDPDLG 480 Query: 670 RNAEMSLYI-------EENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPR 722 N ++S I E ++ SI ++G +++ +FD E + ++A D G P Sbjct: 481 PNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQARDQGSPAL 540 Query: 723 SATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGINA 777 SA ++ + V D NDNAP V P + + ++P ++ +V V+A D+D G NA Sbjct: 541 SANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVTKVVAVDADSGHNA 600 Query: 778 DLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837 L+Y ++ + LF + +G V L + RL+V V D GQP S T +H+ Sbjct: 601 WLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLSATATLHL 660 Query: 838 FVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILI 897 +S+ + DI P + L + V +++V+ ++ + Sbjct: 661 VFADSLQE---------------VLPDITDRPDPSDLQAELQFYLVVALALISVLFLVAM 705 Query: 898 VV 899 ++ Sbjct: 706 IL 707 Score = 110 bits (274), Expect = 9e-24 Identities = 77/274 (28%), Positives = 134/274 (48%), Gaps = 19/274 (6%) Query: 576 SSVMGIFAIDPDSGDILVNTVLDREQ------TDRYEFKVNAKDKGIPVLQGSTTVIVQV 629 SS F + +SG++LV++ LDRE+ EF+ A++ V V++ Sbjct: 69 SSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENP-----LNFYHVNVEI 123 Query: 630 ADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIFSI 687 D ND+ PKF Q+ F + E+ QP + + + DAD G N + + ++ ++ + Sbjct: 124 EDINDHTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINK 183 Query: 688 ENDTGTIYSTM----SFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVT 743 E G+ Y M DRE Q +Y + A+D G PP S+TA + + V D NDNAP + Sbjct: 184 EKSDGSKYPEMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFS 243 Query: 744 LPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSL 803 +++ L + T V V ATD D+G+NA++ +S + F+++ +G +++ Sbjct: 244 --QDVYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEITV 301 Query: 804 VGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837 + L + + +V++ D G T V V Sbjct: 302 LNTLDFEEVKEYSIVLEARDGGGMIAQCTVEVEV 335 >gi|14270508 protocadherin gamma subfamily B, 7 isoform 2 precursor [Homo sapiens] Length = 808 Score = 330 bits (845), Expect = 6e-90 Identities = 229/734 (31%), Positives = 344/734 (46%), Gaps = 105/734 (14%) Query: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVT---GSGEVTFSLESGSEYL 75 LLLPL + +RY + EE +GN+A DLG+ + E+ S E + Sbjct: 20 LLLPLFYPTLC--EPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARELRVSAEK--LHF 75 Query: 76 KIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLD 135 +D +G+L +R IDRE++ C+ + C L E V P +++F V++ D Sbjct: 76 SVDAQSGDLLVKDR-IDREQI--CK---ERRRCELQLEAVVENP----LNIFHVIVVIED 125 Query: 136 INDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGES 195 +ND+ P F + L + E+ +G +L +A D D N + Sbjct: 126 VNDHAPQFRKDEINLEISESVSLGMGTILESAEDPDISMNSL------------------ 167 Query: 196 RRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGE 255 SK +L +E F L D PDG Sbjct: 168 --------------------------SKYQLSPNE------------YFSLVEKDNPDGG 189 Query: 256 KQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEA 315 K P+L+++ LDRE + ++ L L DGGDPPRS A +R+L+ D NDN P F + VY Sbjct: 190 KYPELVLQKTLDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRV 249 Query: 316 DLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDR 375 L E+ PGT IL+++A D D G+N +I Y F + + + LD T+G + +D Sbjct: 250 SLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQQPLDF 309 Query: 376 EEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAED 435 EEV + + A+DRG + + V++ + DENDN P I I + ++D V Sbjct: 310 EEVERYTINIEAKDRGS--LSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPGVV-- 365 Query: 436 VLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDY 495 +AL + D+D GENG V C++ VPF++ +S+ Y L T LD Sbjct: 366 ------VALFKTRDQDSGENGEVRCSLSRGVPFKIHSSSN-------NYYKLVTDEALDR 412 Query: 496 EATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVA 555 E T E+NV I A D G P LSS+ ++ + + D NDN P+FGQS V+ PENN PG +A Sbjct: 413 EQTPEYNVTIAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASIA 472 Query: 556 TVLATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRYEFKV 609 V A+D D G N ++YSL +S + ++ SG + D EQ +E + Sbjct: 473 QVSASDPDFGLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTL 532 Query: 610 NAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNSPVGMVT 662 A+D+G P L + ++ V V D+NDN P+ + V QP V V Sbjct: 533 QARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDTVPRAAQPGYLVTKVV 592 Query: 663 VMDADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720 +DAD G NA +S ++ + + +FS+ TG + + + V DGG P Sbjct: 593 AVDADSGHNAWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAVRDGGQP 652 Query: 721 PRSATATVSLFVMD 734 P SATAT+ L D Sbjct: 653 PLSATATLHLVFAD 666 Score = 241 bits (616), Expect = 2e-63 Identities = 194/679 (28%), Positives = 316/679 (46%), Gaps = 61/679 (8%) Query: 260 LIVKGALDREQ--RDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317 L+VK +DREQ ++ L++ + P + ++ V+I DVND++P+F K ++ Sbjct: 84 LLVKDRIDREQICKERRRCELQLEAVVENPLNIFHVI-VVIEDVNDHAPQFRKDEINLEI 142 Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW----LSVLHRI 373 +E+ + G + A D D+ +N +Y + L+ D G L + + Sbjct: 143 SESVSLGMGTILESAEDPDISMNSLSKYQL--SPNEYFSLVEKDNPDGGKYPELVLQKTL 200 Query: 374 DREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVA 433 DRE + + A D G PP++ A + + + D NDN P + + + R+ L+ Sbjct: 201 DRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDN-PPVFSQDVYRVSLR------- 252 Query: 434 EDVLVDTPIALVQVSDRDQGENGVVTCTVVG--DVPFQLKPASDTEGDQNKKKYFLHTST 491 EDV T I V+ +D+D+G N +T + G D + T G+ + T Sbjct: 253 EDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGN-------ILTQQ 305 Query: 492 PLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPG 551 PLD+E + + I A D GS LS+ +IV+V D NDN P + + E++ PG Sbjct: 306 PLDFEEVERYTINIEAKDRGS--LSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPG 363 Query: 552 ERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGD---ILVNTVLDREQTDRYEFK 608 VA D DSG+N E+ SL V F I S + ++ + LDREQT Y Sbjct: 364 VVVALFKTRDQDSGENGEVRCSLSRGVP--FKIHSSSNNYYKLVTDEALDREQTPEYNVT 421 Query: 609 VNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADK 668 + A D+G P L S T+ + + D NDN P F Q + +V EN QP + + V+ D D Sbjct: 422 IAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASIAQVSASDPDF 481 Query: 669 GRNAEMSLYIEENN-------NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPP 721 G N +S + ++ + S+ +G +++ +FD E T+ ++A D G P Sbjct: 482 GLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPA 541 Query: 722 RSATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGIN 776 SA ++ + V D NDNAP V P + + +P ++ +V V+A D+D G N Sbjct: 542 LSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDTVPRAAQPGYLVTKVVAVDADSGHN 601 Query: 777 ADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVH 836 A L+Y +V + LF + +G V +V L K RL+V V D GQP S T +H Sbjct: 602 AWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAVRDGGQPPLSATATLH 661 Query: 837 VFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIIL 896 + +S+ + D + P+ S+ + + VVA + +L +L Sbjct: 662 LVFADSLQE---------------VLPDFSDHPTPSDSQAEMQFYL-VVALALISVLFLL 705 Query: 897 IVVMARYCRSKNKNGYEAG 915 V++A R + AG Sbjct: 706 AVILAIALRLRQSFSPTAG 724 Score = 186 bits (471), Expect = 1e-46 Identities = 139/501 (27%), Positives = 221/501 (44%), Gaps = 26/501 (5%) Query: 360 LDETSGWLSVLHRIDREEV-NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIR 418 +D SG L V RIDRE++ + R + + + V++ I+D ND+ P Sbjct: 77 VDAQSGDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKD 136 Query: 419 KIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEG 478 +I ++E V + L D D N + + + F L + +G Sbjct: 137 EIN--------LEISESVSLGMGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDG 188 Query: 479 DQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQS 538 + + T LD E ++V+ A+D G P S + + V D NDNPP+F Q Sbjct: 189 GKYPELVLQKT---LDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQD 245 Query: 539 VVEVYFPENNIPGERVATVLATDADSGKNAEIAYS---LDSSVMGIFAIDPDSGDILVNT 595 V V E+ PG + V ATD D G N+EI YS + +F++D +G+IL Sbjct: 246 VYRVSLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQQ 305 Query: 596 VLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPN 655 LD E+ +RY + AKD+G L VIV+V D+NDN P+ + + + E+ P Sbjct: 306 PLDFEEVERYTINIEAKDRG--SLSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPG 363 Query: 656 SPVGMVTVMDADKGRNAEMSLYIEEN--NNIFSIENDTGTIYSTMSFDREHQTTYTFRVK 713 V + D D G N E+ + I S N+ + + + DRE Y + Sbjct: 364 VVVALFKTRDQDSGENGEVRCSLSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIA 423 Query: 714 AVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDD 773 A D G PP S++ T++L + D NDNAP ++ +P ++ +A V A+D D Sbjct: 424 ATDRGKPPLSSSKTITLHITDVNDNAP--VFGQSAYLVHVPENNQPGASIAQVSASDPDF 481 Query: 774 GINADLNYSIVGGN-----PFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPS 828 G+N ++YS++ + + SGVV + L +Q D G P+ Sbjct: 482 GLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPA 541 Query: 829 QSTTTLVHVFVNESVSNATAI 849 S + V V + NA + Sbjct: 542 LSANVSLRVLVGDRNDNAPRV 562 Score = 103 bits (257), Expect = 9e-22 Identities = 80/273 (29%), Positives = 133/273 (48%), Gaps = 27/273 (9%) Query: 582 FAIDPDSGDILVNTVLDREQ----TDRYEFKVNA-KDKGIPVLQGSTTVIVQVADKNDND 636 F++D SGD+LV +DREQ R E ++ A + + + VIV + D ND+ Sbjct: 75 FSVDAQSGDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFH----VIVVIEDVNDHA 130 Query: 637 PKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEM---SLYIEENNNIFSI---END 690 P+F +D + E++ +GM T++++ + + M S Y N FS+ +N Sbjct: 131 PQFRKDEINLEISESVS----LGMGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNP 186 Query: 691 TGTIYSTM----SFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPK 746 G Y + + DRE Q+ + + A+DGGDPPRS TA + + V+D NDN P + + Sbjct: 187 DGGKYPELVLQKTLDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFS--Q 244 Query: 747 NISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVG--GNPFKLFEIDPTSGVVSLV 804 ++ L T + V ATD D+GIN+++ YS G +F +D T+G + Sbjct: 245 DVYRVSLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQ 304 Query: 805 GKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837 L + + + ++ D G S +V V Sbjct: 305 QPLDFEEVERYTINIEAKDRGSLSTRCKVIVEV 337 >gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precursor [Homo sapiens] Length = 929 Score = 330 bits (845), Expect = 6e-90 Identities = 229/734 (31%), Positives = 344/734 (46%), Gaps = 105/734 (14%) Query: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVT---GSGEVTFSLESGSEYL 75 LLLPL + +RY + EE +GN+A DLG+ + E+ S E + Sbjct: 20 LLLPLFYPTLC--EPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARELRVSAEK--LHF 75 Query: 76 KIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLD 135 +D +G+L +R IDRE++ C+ + C L E V P +++F V++ D Sbjct: 76 SVDAQSGDLLVKDR-IDREQI--CK---ERRRCELQLEAVVENP----LNIFHVIVVIED 125 Query: 136 INDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGES 195 +ND+ P F + L + E+ +G +L +A D D N + Sbjct: 126 VNDHAPQFRKDEINLEISESVSLGMGTILESAEDPDISMNSL------------------ 167 Query: 196 RRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGE 255 SK +L +E F L D PDG Sbjct: 168 --------------------------SKYQLSPNE------------YFSLVEKDNPDGG 189 Query: 256 KQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEA 315 K P+L+++ LDRE + ++ L L DGGDPPRS A +R+L+ D NDN P F + VY Sbjct: 190 KYPELVLQKTLDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRV 249 Query: 316 DLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDR 375 L E+ PGT IL+++A D D G+N +I Y F + + + LD T+G + +D Sbjct: 250 SLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQQPLDF 309 Query: 376 EEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAED 435 EEV + + A+DRG + + V++ + DENDN P I I + ++D V Sbjct: 310 EEVERYTINIEAKDRGS--LSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPGVV-- 365 Query: 436 VLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDY 495 +AL + D+D GENG V C++ VPF++ +S+ Y L T LD Sbjct: 366 ------VALFKTRDQDSGENGEVRCSLSRGVPFKIHSSSN-------NYYKLVTDEALDR 412 Query: 496 EATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVA 555 E T E+NV I A D G P LSS+ ++ + + D NDN P+FGQS V+ PENN PG +A Sbjct: 413 EQTPEYNVTIAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASIA 472 Query: 556 TVLATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRYEFKV 609 V A+D D G N ++YSL +S + ++ SG + D EQ +E + Sbjct: 473 QVSASDPDFGLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTL 532 Query: 610 NAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNSPVGMVT 662 A+D+G P L + ++ V V D+NDN P+ + V QP V V Sbjct: 533 QARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDTVPRAAQPGYLVTKVV 592 Query: 663 VMDADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720 +DAD G NA +S ++ + + +FS+ TG + + + V DGG P Sbjct: 593 AVDADSGHNAWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAVRDGGQP 652 Query: 721 PRSATATVSLFVMD 734 P SATAT+ L D Sbjct: 653 PLSATATLHLVFAD 666 Score = 241 bits (616), Expect = 2e-63 Identities = 194/679 (28%), Positives = 316/679 (46%), Gaps = 61/679 (8%) Query: 260 LIVKGALDREQ--RDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317 L+VK +DREQ ++ L++ + P + ++ V+I DVND++P+F K ++ Sbjct: 84 LLVKDRIDREQICKERRRCELQLEAVVENPLNIFHVI-VVIEDVNDHAPQFRKDEINLEI 142 Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW----LSVLHRI 373 +E+ + G + A D D+ +N +Y + L+ D G L + + Sbjct: 143 SESVSLGMGTILESAEDPDISMNSLSKYQL--SPNEYFSLVEKDNPDGGKYPELVLQKTL 200 Query: 374 DREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVA 433 DRE + + A D G PP++ A + + + D NDN P + + + R+ L+ Sbjct: 201 DRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDN-PPVFSQDVYRVSLR------- 252 Query: 434 EDVLVDTPIALVQVSDRDQGENGVVTCTVVG--DVPFQLKPASDTEGDQNKKKYFLHTST 491 EDV T I V+ +D+D+G N +T + G D + T G+ + T Sbjct: 253 EDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGN-------ILTQQ 305 Query: 492 PLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPG 551 PLD+E + + I A D GS LS+ +IV+V D NDN P + + E++ PG Sbjct: 306 PLDFEEVERYTINIEAKDRGS--LSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPG 363 Query: 552 ERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGD---ILVNTVLDREQTDRYEFK 608 VA D DSG+N E+ SL V F I S + ++ + LDREQT Y Sbjct: 364 VVVALFKTRDQDSGENGEVRCSLSRGVP--FKIHSSSNNYYKLVTDEALDREQTPEYNVT 421 Query: 609 VNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADK 668 + A D+G P L S T+ + + D NDN P F Q + +V EN QP + + V+ D D Sbjct: 422 IAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASIAQVSASDPDF 481 Query: 669 GRNAEMSLYIEENN-------NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPP 721 G N +S + ++ + S+ +G +++ +FD E T+ ++A D G P Sbjct: 482 GLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPA 541 Query: 722 RSATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGIN 776 SA ++ + V D NDNAP V P + + +P ++ +V V+A D+D G N Sbjct: 542 LSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDTVPRAAQPGYLVTKVVAVDADSGHN 601 Query: 777 ADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVH 836 A L+Y +V + LF + +G V +V L K RL+V V D GQP S T +H Sbjct: 602 AWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAVRDGGQPPLSATATLH 661 Query: 837 VFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIIL 896 + +S+ + D + P+ S+ + + VVA + +L +L Sbjct: 662 LVFADSLQE---------------VLPDFSDHPTPSDSQAEMQFYL-VVALALISVLFLL 705 Query: 897 IVVMARYCRSKNKNGYEAG 915 V++A R + AG Sbjct: 706 AVILAIALRLRQSFSPTAG 724 Score = 186 bits (471), Expect = 1e-46 Identities = 139/501 (27%), Positives = 221/501 (44%), Gaps = 26/501 (5%) Query: 360 LDETSGWLSVLHRIDREEV-NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIR 418 +D SG L V RIDRE++ + R + + + V++ I+D ND+ P Sbjct: 77 VDAQSGDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKD 136 Query: 419 KIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEG 478 +I ++E V + L D D N + + + F L + +G Sbjct: 137 EIN--------LEISESVSLGMGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDG 188 Query: 479 DQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQS 538 + + T LD E ++V+ A+D G P S + + V D NDNPP+F Q Sbjct: 189 GKYPELVLQKT---LDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQD 245 Query: 539 VVEVYFPENNIPGERVATVLATDADSGKNAEIAYS---LDSSVMGIFAIDPDSGDILVNT 595 V V E+ PG + V ATD D G N+EI YS + +F++D +G+IL Sbjct: 246 VYRVSLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQQ 305 Query: 596 VLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPN 655 LD E+ +RY + AKD+G L VIV+V D+NDN P+ + + + E+ P Sbjct: 306 PLDFEEVERYTINIEAKDRG--SLSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPG 363 Query: 656 SPVGMVTVMDADKGRNAEMSLYIEEN--NNIFSIENDTGTIYSTMSFDREHQTTYTFRVK 713 V + D D G N E+ + I S N+ + + + DRE Y + Sbjct: 364 VVVALFKTRDQDSGENGEVRCSLSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIA 423 Query: 714 AVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDD 773 A D G PP S++ T++L + D NDNAP ++ +P ++ +A V A+D D Sbjct: 424 ATDRGKPPLSSSKTITLHITDVNDNAP--VFGQSAYLVHVPENNQPGASIAQVSASDPDF 481 Query: 774 GINADLNYSIVGGN-----PFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPS 828 G+N ++YS++ + + SGVV + L +Q D G P+ Sbjct: 482 GLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPA 541 Query: 829 QSTTTLVHVFVNESVSNATAI 849 S + V V + NA + Sbjct: 542 LSANVSLRVLVGDRNDNAPRV 562 Score = 103 bits (257), Expect = 9e-22 Identities = 80/273 (29%), Positives = 133/273 (48%), Gaps = 27/273 (9%) Query: 582 FAIDPDSGDILVNTVLDREQ----TDRYEFKVNA-KDKGIPVLQGSTTVIVQVADKNDND 636 F++D SGD+LV +DREQ R E ++ A + + + VIV + D ND+ Sbjct: 75 FSVDAQSGDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFH----VIVVIEDVNDHA 130 Query: 637 PKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEM---SLYIEENNNIFSI---END 690 P+F +D + E++ +GM T++++ + + M S Y N FS+ +N Sbjct: 131 PQFRKDEINLEISESVS----LGMGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNP 186 Query: 691 TGTIYSTM----SFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPK 746 G Y + + DRE Q+ + + A+DGGDPPRS TA + + V+D NDN P + + Sbjct: 187 DGGKYPELVLQKTLDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFS--Q 244 Query: 747 NISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVG--GNPFKLFEIDPTSGVVSLV 804 ++ L T + V ATD D+GIN+++ YS G +F +D T+G + Sbjct: 245 DVYRVSLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQ 304 Query: 805 GKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837 L + + + ++ D G S +V V Sbjct: 305 QPLDFEEVERYTINIEAKDRGSLSTRCKVIVEV 337 >gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precursor [Homo sapiens] Length = 878 Score = 322 bits (825), Expect = 1e-87 Identities = 234/758 (30%), Positives = 348/758 (45%), Gaps = 106/758 (13%) Query: 34 LRYRLAEEGPADVRIGNVASDLGIVTG---SGEVTFSLESGSEYLKIDNLTGELSTSERR 90 LRY + EE +GNVA DLG+ S + E Y + ++G L+ +++ Sbjct: 31 LRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQK- 89 Query: 91 IDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTL 150 IDRE L C L +V P ++L +V +LD+NDN+P+F +P + Sbjct: 90 IDRESLCGAS-----TSCLLPVQVVTEHP----LELIRVEVEILDLNDNSPSFATPEREM 140 Query: 151 TVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGGG 210 + E+ G + L DSA P G Sbjct: 141 RISESAASGARFPL-------------------------------------DSAQDPDVG 163 Query: 211 GNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQ 270 N S +S F L V DG+ P+L+++ LDRE Sbjct: 164 TNTVS-------------------FYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREA 204 Query: 271 RDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQL 330 + ++L L DGG P RS ++ V++ D+NDN+P F+ SV + EN+ GT +L+L Sbjct: 205 QARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRL 264 Query: 331 RAADLDVGVNGQIEYVFGAAT-ESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARD 389 A D D G NGQ++Y FG T E+VR L LD +SG + VL ID EE ARD Sbjct: 265 NATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARD 324 Query: 390 RGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSD 449 +GQP + +++ D NDN P + + + V E V T + L V D Sbjct: 325 QGQPAMEGHCVIQVDVGDVNDNAPEVLLASLAN--------PVLESTPVGTVVGLFNVRD 376 Query: 450 RDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVD 509 RD G NG V+ + D+PFQ+KP ++ Y L TS PLD EAT + + ++A D Sbjct: 377 RDSGRNGEVSLDISPDLPFQIKP--------SENHYSLLTSQPLDREATSHYIIELLASD 428 Query: 510 SGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAE 569 +GSPSL + ++ + + D NDN P F Q + Y EN PG + TV A+D D+G NA Sbjct: 429 AGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNAR 488 Query: 570 IAYSL-DSSVMGIFA-----IDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGST 623 + YS+ + V G A ++P+ G I D E + V +D G P L +T Sbjct: 489 LTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANT 548 Query: 624 TVIVQVADKNDNDPKFM------QDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLY 677 ++ V V D+NDN P + + + + P S V VT +DAD G NA +S Sbjct: 549 SLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYS 608 Query: 678 IEENN---NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMD 734 + + +F + TG + + + + T V D GDP S+TATV L + D Sbjct: 609 LLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLED 668 Query: 735 ENDNAPTVTLPKNISYTLLPPS-SNVRTVVATVLATDS 771 E+ +PK+ + + PP S++ + LAT S Sbjct: 669 EDPE----EMPKSSDFLIHPPERSDLTLYLIVALATVS 702 Score = 208 bits (529), Expect = 2e-53 Identities = 178/649 (27%), Positives = 290/649 (44%), Gaps = 67/649 (10%) Query: 294 LRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATES 353 + V I D+NDNSP F E ++E++A G A D DVG N Y + Sbjct: 119 VEVEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHF 178 Query: 354 VRRLLRLDETSGW--LSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDN 411 + L + + L + ++DRE + + + A D G P ++ + + + D NDN Sbjct: 179 SLNVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDN 238 Query: 412 VPSIE--IRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVV-------TCTV 462 P+ + + ++G + E+ + T + + +D D+G NG + T Sbjct: 239 APTFQSSVLRVG----------IPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEA 288 Query: 463 VGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLI 522 V ++ F L P+S +H P+D+E +R + + A D G P++ + + Sbjct: 289 VRNL-FGLDPSSGA----------IHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQ 337 Query: 523 VKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIF 582 V VGD NDN P + + E+ G V D DSG+N E+ SLD S F Sbjct: 338 VDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEV--SLDISPDLPF 395 Query: 583 AIDPDSG--DILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFM 640 I P +L + LDRE T Y ++ A D G P L T+ + ++D NDN P+F Sbjct: 396 QIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFN 455 Query: 641 QDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEEN-------NNIFSIENDTGT 693 Q ++T Y+ EN P S + V D D G NA ++ I N ++ + + G Sbjct: 456 QQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGR 515 Query: 694 IYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPK----NIS 749 I++ +FD E V D G PP A ++ +FV+DENDNAP V P+ + + Sbjct: 516 IFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSA 575 Query: 750 YTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFK-LFEIDPTSGVVSLVGKLT 808 LP S+ ++V V A D+D G NA L+YS++ + LF + +G V L Sbjct: 576 PQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALL 635 Query: 809 QKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGD 868 + ++VV V D+G PS S+T V + + + +P + D Sbjct: 636 EDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE------------EMPKSSDFLIH 683 Query: 869 PSYEISKQRLSIVIGVVAGIMTVILIILI--VVMARYCRSKNKNGYEAG 915 P +R + + ++ + TV L+ L+ ++ C N +G G Sbjct: 684 P-----PERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADGDGGG 727 Score = 102 bits (253), Expect = 3e-21 Identities = 79/286 (27%), Positives = 129/286 (45%), Gaps = 28/286 (9%) Query: 582 FAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTT-------VIVQVADKND 634 F++ SG + VN +DRE A + +Q T V V++ D ND Sbjct: 75 FSLSLMSGALAVNQKIDRESL------CGASTSCLLPVQVVTEHPLELIRVEVEILDLND 128 Query: 635 NDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDT--- 691 N P F + E+ + + + D D G N +S Y N+ FS+ T Sbjct: 129 NSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNT-VSFYTLSPNSHFSLNVKTLKD 187 Query: 692 ----GTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKN 747 + DRE Q + + AVDGG P RS T +S+ V+D NDNAPT + Sbjct: 188 GKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPT--FQSS 245 Query: 748 ISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFK----LFEIDPTSGVVSL 803 + +P ++ + T++ + ATD D+G N L+YS G + + LF +DP+SG + + Sbjct: 246 VLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSF-GDHTSEAVRNLFGLDPSSGAIHV 304 Query: 804 VGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAI 849 +G + + + + + D GQP+ ++ V V + NA + Sbjct: 305 LGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEV 350 Score = 48.9 bits (115), Expect = 3e-05 Identities = 56/221 (25%), Positives = 91/221 (41%), Gaps = 16/221 (7%) Query: 646 FYVKENLQPNSPVGMVTV---MDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDR 702 + V E +P + VG V + + + L EEN FS+ +G + DR Sbjct: 33 YSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQKIDR 92 Query: 703 EH----QTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSN 758 E T+ V+ V + P V + ++D NDN+P+ P+ +S Sbjct: 93 ESLCGASTSCLLPVQVVT--EHPLE-LIRVEVEILDLNDNSPSFATPEREMRISESAASG 149 Query: 759 VRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSG----VVSLVGKLTQKHYGL 814 R + + A D D G N Y++ + F L G + L +L ++ Sbjct: 150 ARFPLDS--AQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQAR 207 Query: 815 HRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIAR 855 H+LV+ D G P++S TTL+ V V + NA S + R Sbjct: 208 HQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLR 248 >gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor [Homo sapiens] Length = 944 Score = 322 bits (825), Expect = 1e-87 Identities = 234/758 (30%), Positives = 348/758 (45%), Gaps = 106/758 (13%) Query: 34 LRYRLAEEGPADVRIGNVASDLGIVTG---SGEVTFSLESGSEYLKIDNLTGELSTSERR 90 LRY + EE +GNVA DLG+ S + E Y + ++G L+ +++ Sbjct: 31 LRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQK- 89 Query: 91 IDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTL 150 IDRE L C L +V P ++L +V +LD+NDN+P+F +P + Sbjct: 90 IDRESLCGAS-----TSCLLPVQVVTEHP----LELIRVEVEILDLNDNSPSFATPEREM 140 Query: 151 TVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGGG 210 + E+ G + L DSA P G Sbjct: 141 RISESAASGARFPL-------------------------------------DSAQDPDVG 163 Query: 211 GNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQ 270 N S +S F L V DG+ P+L+++ LDRE Sbjct: 164 TNTVS-------------------FYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREA 204 Query: 271 RDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQL 330 + ++L L DGG P RS ++ V++ D+NDN+P F+ SV + EN+ GT +L+L Sbjct: 205 QARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRL 264 Query: 331 RAADLDVGVNGQIEYVFGAAT-ESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARD 389 A D D G NGQ++Y FG T E+VR L LD +SG + VL ID EE ARD Sbjct: 265 NATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARD 324 Query: 390 RGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSD 449 +GQP + +++ D NDN P + + + V E V T + L V D Sbjct: 325 QGQPAMEGHCVIQVDVGDVNDNAPEVLLASLAN--------PVLESTPVGTVVGLFNVRD 376 Query: 450 RDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVD 509 RD G NG V+ + D+PFQ+KP ++ Y L TS PLD EAT + + ++A D Sbjct: 377 RDSGRNGEVSLDISPDLPFQIKP--------SENHYSLLTSQPLDREATSHYIIELLASD 428 Query: 510 SGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAE 569 +GSPSL + ++ + + D NDN P F Q + Y EN PG + TV A+D D+G NA Sbjct: 429 AGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNAR 488 Query: 570 IAYSL-DSSVMGIFA-----IDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGST 623 + YS+ + V G A ++P+ G I D E + V +D G P L +T Sbjct: 489 LTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANT 548 Query: 624 TVIVQVADKNDNDPKFM------QDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLY 677 ++ V V D+NDN P + + + + P S V VT +DAD G NA +S Sbjct: 549 SLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYS 608 Query: 678 IEENN---NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMD 734 + + +F + TG + + + + T V D GDP S+TATV L + D Sbjct: 609 LLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLED 668 Query: 735 ENDNAPTVTLPKNISYTLLPPS-SNVRTVVATVLATDS 771 E+ +PK+ + + PP S++ + LAT S Sbjct: 669 EDPE----EMPKSSDFLIHPPERSDLTLYLIVALATVS 702 Score = 208 bits (529), Expect = 2e-53 Identities = 178/649 (27%), Positives = 290/649 (44%), Gaps = 67/649 (10%) Query: 294 LRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATES 353 + V I D+NDNSP F E ++E++A G A D DVG N Y + Sbjct: 119 VEVEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHF 178 Query: 354 VRRLLRLDETSGW--LSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDN 411 + L + + L + ++DRE + + + A D G P ++ + + + D NDN Sbjct: 179 SLNVKTLKDGKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDN 238 Query: 412 VPSIE--IRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVV-------TCTV 462 P+ + + ++G + E+ + T + + +D D+G NG + T Sbjct: 239 APTFQSSVLRVG----------IPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEA 288 Query: 463 VGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLI 522 V ++ F L P+S +H P+D+E +R + + A D G P++ + + Sbjct: 289 VRNL-FGLDPSSGA----------IHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQ 337 Query: 523 VKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIF 582 V VGD NDN P + + E+ G V D DSG+N E+ SLD S F Sbjct: 338 VDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEV--SLDISPDLPF 395 Query: 583 AIDPDSG--DILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFM 640 I P +L + LDRE T Y ++ A D G P L T+ + ++D NDN P+F Sbjct: 396 QIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFN 455 Query: 641 QDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEEN-------NNIFSIENDTGT 693 Q ++T Y+ EN P S + V D D G NA ++ I N ++ + + G Sbjct: 456 QQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGR 515 Query: 694 IYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPK----NIS 749 I++ +FD E V D G PP A ++ +FV+DENDNAP V P+ + + Sbjct: 516 IFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSA 575 Query: 750 YTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFK-LFEIDPTSGVVSLVGKLT 808 LP S+ ++V V A D+D G NA L+YS++ + LF + +G V L Sbjct: 576 PQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALL 635 Query: 809 QKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGD 868 + ++VV V D+G PS S+T V + + + +P + D Sbjct: 636 EDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE------------EMPKSSDFLIH 683 Query: 869 PSYEISKQRLSIVIGVVAGIMTVILIILI--VVMARYCRSKNKNGYEAG 915 P +R + + ++ + TV L+ L+ ++ C N +G G Sbjct: 684 P-----PERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADGDGGG 727 Score = 102 bits (253), Expect = 3e-21 Identities = 79/286 (27%), Positives = 129/286 (45%), Gaps = 28/286 (9%) Query: 582 FAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTT-------VIVQVADKND 634 F++ SG + VN +DRE A + +Q T V V++ D ND Sbjct: 75 FSLSLMSGALAVNQKIDRESL------CGASTSCLLPVQVVTEHPLELIRVEVEILDLND 128 Query: 635 NDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDT--- 691 N P F + E+ + + + D D G N +S Y N+ FS+ T Sbjct: 129 NSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNT-VSFYTLSPNSHFSLNVKTLKD 187 Query: 692 ----GTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKN 747 + DRE Q + + AVDGG P RS T +S+ V+D NDNAPT + Sbjct: 188 GKPFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPT--FQSS 245 Query: 748 ISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFK----LFEIDPTSGVVSL 803 + +P ++ + T++ + ATD D+G N L+YS G + + LF +DP+SG + + Sbjct: 246 VLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSF-GDHTSEAVRNLFGLDPSSGAIHV 304 Query: 804 VGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAI 849 +G + + + + + D GQP+ ++ V V + NA + Sbjct: 305 LGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEV 350 Score = 48.9 bits (115), Expect = 3e-05 Identities = 56/221 (25%), Positives = 91/221 (41%), Gaps = 16/221 (7%) Query: 646 FYVKENLQPNSPVGMVTV---MDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDR 702 + V E +P + VG V + + + L EEN FS+ +G + DR Sbjct: 33 YSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQKIDR 92 Query: 703 EH----QTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSN 758 E T+ V+ V + P V + ++D NDN+P+ P+ +S Sbjct: 93 ESLCGASTSCLLPVQVVT--EHPLE-LIRVEVEILDLNDNSPSFATPEREMRISESAASG 149 Query: 759 VRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSG----VVSLVGKLTQKHYGL 814 R + + A D D G N Y++ + F L G + L +L ++ Sbjct: 150 ARFPLDS--AQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQAR 207 Query: 815 HRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIAR 855 H+LV+ D G P++S TTL+ V V + NA S + R Sbjct: 208 HQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLR 248 >gi|11128029 protocadherin gamma subfamily B, 6 isoform 1 precursor [Homo sapiens] Length = 930 Score = 321 bits (823), Expect = 2e-87 Identities = 229/738 (31%), Positives = 343/738 (46%), Gaps = 109/738 (14%) Query: 19 LLLPLSLSL--AAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYL 75 +L PL L L + +RY + EE +GN+A DLG+ V + + + Sbjct: 16 VLFPLLLPLFYPTLSEPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARKLRVSAEKLHF 75 Query: 76 KIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLD 135 +D +G+L + RIDRE++ C+ + C L E V P +++F V++ D Sbjct: 76 SVDAESGDLLV-KNRIDREQI--CK---ERRRCELQLEAVVENP----LNIFHVIVVIED 125 Query: 136 INDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGES 195 +ND+ P F + L + E+ GT L ATD D N I+ Y++ Sbjct: 126 VNDHAPQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKI------------- 172 Query: 196 RRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGE 255 +S PY F L V DG Sbjct: 173 ------NSNPY-------------------------------------FSLMVRVNSDGG 189 Query: 256 KQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEA 315 K P+L ++ LDRE++ S+ L L DGGDPPRS+ A + + + D NDN P F + Y Sbjct: 190 KYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYRI 249 Query: 316 DLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDR 375 L+EN PG+P+LQ+ A D D GVN +I Y F + +S + + LDE +G + D Sbjct: 250 SLSENLPPGSPVLQVTATDQDEGVNAEINYYFRSTAQSTKHMFSLDEKTGMIKNNQSFDF 309 Query: 376 EEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAED 435 E+V + V A+D G + + V++ I DENDN P I I ++++ Sbjct: 310 EDVERYTMEVEAKDGG--GLSTQCKVIIEILDENDNSPEIII------------TSLSDQ 355 Query: 436 VLVDTP----IALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTST 491 +L ++P +AL + D D G NG V C + D+PF++ +S+ Y L T Sbjct: 356 ILENSPPGMVVALFKTRDLDFGGNGEVRCNIETDIPFKIYSSSN-------NYYKLVTDG 408 Query: 492 PLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPG 551 LD E T E+NV IVA D G P LSS+ S+ + V D NDN P+F Q+ V+ ENN PG Sbjct: 409 ALDREQTPEYNVTIVATDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPG 468 Query: 552 ERVATVLATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRY 605 +A V A+D D G N I+YS+ +S V ++ SG + D EQ + Sbjct: 469 ASIAQVSASDPDLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAF 528 Query: 606 EFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNSPV 658 + A+D G P L + ++ V V D+NDN P+ + F V + +P V Sbjct: 529 ALTLQARDHGSPTLSANVSLRVLVGDRNDNAPRVLYPALGPDGSAFFDMVPRSAEPGYLV 588 Query: 659 GMVTVMDADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVD 716 V +DAD G NA +S ++ + + +FS+ TG + + + V D Sbjct: 589 TKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRD 648 Query: 717 GGDPPRSATATVSLFVMD 734 GG PP SATAT+ L D Sbjct: 649 GGQPPLSATATLHLVFAD 666 Score = 228 bits (581), Expect = 2e-59 Identities = 171/660 (25%), Positives = 310/660 (46%), Gaps = 54/660 (8%) Query: 260 LIVKGALDREQ--RDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317 L+VK +DREQ ++ L++ + P + ++ V+I DVND++P+F+K ++ Sbjct: 84 LLVKNRIDREQICKERRRCELQLEAVVENPLNIFHVI-VVIEDVNDHAPQFDKKEIHLEI 142 Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW---LSVLHRID 374 E+++ GT + A D D+ +N +Y + ++R++ G LS+ +D Sbjct: 143 FESASAGTRLSLDPATDPDININSIKDYKINS-NPYFSLMVRVNSDGGKYPELSLEKLLD 201 Query: 375 REEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAE 434 REE + A D G PP++ A + +++KD NDN P + R RI L +E Sbjct: 202 REEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDN-PPVFSRDEYRISL-------SE 253 Query: 435 DVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEG--DQNKKKYFLHTSTP 492 ++ +P+ V +D+D+G N + + A T+ ++K + + Sbjct: 254 NLPPGSPVLQVTATDQDEGVNAEINY-------YFRSTAQSTKHMFSLDEKTGMIKNNQS 306 Query: 493 LDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGE 552 D+E + + + A D G LS+ +I+++ D NDN P + + EN+ PG Sbjct: 307 FDFEDVERYTMEVEAKDGGG--LSTQCKVIIEILDENDNSPEIIITSLSDQILENSPPGM 364 Query: 553 RVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFKVNA 611 VA D D G N E+ ++++ + I++ + ++ + LDREQT Y + A Sbjct: 365 VVALFKTRDLDFGGNGEVRCNIETDIPFKIYSSSNNYYKLVTDGALDREQTPEYNVTIVA 424 Query: 612 KDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRN 671 D+G P L S ++ + VAD NDN P F Q + +V EN P + + V+ D D G N Sbjct: 425 TDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPGASIAQVSASDPDLGLN 484 Query: 672 AEMSLYIEENN-------NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSA 724 +S I ++ + S+ +G +++ +FD E + ++A D G P SA Sbjct: 485 GHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGSPTLSA 544 Query: 725 TATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGINADL 779 ++ + V D NDNAP V P + + ++P S+ +V V+A D+D G NA L Sbjct: 545 NVSLRVLVGDRNDNAPRVLYPALGPDGSAFFDMVPRSAEPGYLVTKVVAVDADSGHNAWL 604 Query: 780 NYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFV 839 +Y ++ + LF + +G V L + RL+V V D GQP S T +H+ Sbjct: 605 SYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVF 664 Query: 840 NESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVV 899 +++ + D++ P + L + V +++V+ ++ +++ Sbjct: 665 ADNLQE---------------ILPDLSDRPVLSDPQAELQFYLVVALALISVLFLLAVIL 709 Score = 192 bits (489), Expect = 1e-48 Identities = 146/503 (29%), Positives = 230/503 (45%), Gaps = 30/503 (5%) Query: 360 LDETSGWLSVLHRIDREEV-NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIR 418 +D SG L V +RIDRE++ + R + + + V++ I+D ND+ P + + Sbjct: 77 VDAESGDLLVKNRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFDKK 136 Query: 419 KIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEG 478 +I + E T ++L +D D N + + + F L +++G Sbjct: 137 EIH--------LEIFESASAGTRLSLDPATDPDININSIKDYKINSNPYFSLMVRVNSDG 188 Query: 479 DQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQS 538 + + L LD E R ++++ A+D G P S+ + + V DTNDNPP+F + Sbjct: 189 GKYPE---LSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRD 245 Query: 539 VVEVYFPENNIPGERVATVLATDADSGKNAEIAY---SLDSSVMGIFAIDPDSGDILVNT 595 + EN PG V V ATD D G NAEI Y S S +F++D +G I N Sbjct: 246 EYRISLSENLPPGSPVLQVTATDQDEGVNAEINYYFRSTAQSTKHMFSLDEKTGMIKNNQ 305 Query: 596 VLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPN 655 D E +RY +V AKD G L VI+++ D+NDN P+ + + + EN P Sbjct: 306 SFDFEDVERYTMEVEAKDGG--GLSTQCKVIIEILDENDNSPEIIITSLSDQILENSPPG 363 Query: 656 SPVGMVTVMDADKGRNAEMSLYIEEN--NNIFSIENDTGTIYSTMSFDREHQTTYTFRVK 713 V + D D G N E+ IE + I+S N+ + + + DRE Y + Sbjct: 364 MVVALFKTRDLDFGGNGEVRCNIETDIPFKIYSSSNNYYKLVTDGALDREQTPEYNVTIV 423 Query: 714 AVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTL--LPPSSNVRTVVATVLATDS 771 A D G PP S++ +++L+V D NDNAP + + PP ++ +A V A+D Sbjct: 424 ATDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPGAS----IAQVSASDP 479 Query: 772 DDGINADLNYSIVGGNPFKL-----FEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQ 826 D G+N ++YSIV + L + SGVV + L +Q D G Sbjct: 480 DLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGS 539 Query: 827 PSQSTTTLVHVFVNESVSNATAI 849 P+ S + V V + NA + Sbjct: 540 PTLSANVSLRVLVGDRNDNAPRV 562 Score = 98.6 bits (244), Expect = 3e-20 Identities = 80/277 (28%), Positives = 131/277 (47%), Gaps = 35/277 (12%) Query: 582 FAIDPDSGDILVNTVLDREQT----DRYEFKVNAK-DKGIPVLQGSTTVIVQVADKNDND 636 F++D +SGD+LV +DREQ R E ++ A + + + VIV + D ND+ Sbjct: 75 FSVDAESGDLLVKNRIDREQICKERRRCELQLEAVVENPLNIFH----VIVVIEDVNDHA 130 Query: 637 PKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIE---NDTGT 693 P+F + + E+ + + + D D N+ + Y +N FS+ N G Sbjct: 131 PQFDKKEIHLEIFESASAGTRLSLDPATDPDININS-IKDYKINSNPYFSLMVRVNSDGG 189 Query: 694 IYSTMSF----DREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-------V 742 Y +S DRE Q +++ + A+DGGDPPRSATA + + V D NDN P + Sbjct: 190 KYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYRI 249 Query: 743 TLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSI--VGGNPFKLFEIDPTSGV 800 +L +N LPP S V V ATD D+G+NA++NY + +F +D +G+ Sbjct: 250 SLSEN-----LPPGS----PVLQVTATDQDEGVNAEINYYFRSTAQSTKHMFSLDEKTGM 300 Query: 801 VSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837 + + + + V+ D G S ++ + Sbjct: 301 IKNNQSFDFEDVERYTMEVEAKDGGGLSTQCKVIIEI 337 >gi|14270502 protocadherin gamma subfamily B, 6 isoform 2 precursor [Homo sapiens] Length = 820 Score = 321 bits (823), Expect = 2e-87 Identities = 229/738 (31%), Positives = 343/738 (46%), Gaps = 109/738 (14%) Query: 19 LLLPLSLSL--AAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYL 75 +L PL L L + +RY + EE +GN+A DLG+ V + + + Sbjct: 16 VLFPLLLPLFYPTLSEPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARKLRVSAEKLHF 75 Query: 76 KIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLD 135 +D +G+L + RIDRE++ C+ + C L E V P +++F V++ D Sbjct: 76 SVDAESGDLLV-KNRIDREQI--CK---ERRRCELQLEAVVENP----LNIFHVIVVIED 125 Query: 136 INDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGES 195 +ND+ P F + L + E+ GT L ATD D N I+ Y++ Sbjct: 126 VNDHAPQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKI------------- 172 Query: 196 RRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGE 255 +S PY F L V DG Sbjct: 173 ------NSNPY-------------------------------------FSLMVRVNSDGG 189 Query: 256 KQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEA 315 K P+L ++ LDRE++ S+ L L DGGDPPRS+ A + + + D NDN P F + Y Sbjct: 190 KYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYRI 249 Query: 316 DLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDR 375 L+EN PG+P+LQ+ A D D GVN +I Y F + +S + + LDE +G + D Sbjct: 250 SLSENLPPGSPVLQVTATDQDEGVNAEINYYFRSTAQSTKHMFSLDEKTGMIKNNQSFDF 309 Query: 376 EEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAED 435 E+V + V A+D G + + V++ I DENDN P I I ++++ Sbjct: 310 EDVERYTMEVEAKDGG--GLSTQCKVIIEILDENDNSPEIII------------TSLSDQ 355 Query: 436 VLVDTP----IALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTST 491 +L ++P +AL + D D G NG V C + D+PF++ +S+ Y L T Sbjct: 356 ILENSPPGMVVALFKTRDLDFGGNGEVRCNIETDIPFKIYSSSN-------NYYKLVTDG 408 Query: 492 PLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPG 551 LD E T E+NV IVA D G P LSS+ S+ + V D NDN P+F Q+ V+ ENN PG Sbjct: 409 ALDREQTPEYNVTIVATDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPG 468 Query: 552 ERVATVLATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRY 605 +A V A+D D G N I+YS+ +S V ++ SG + D EQ + Sbjct: 469 ASIAQVSASDPDLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAF 528 Query: 606 EFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNSPV 658 + A+D G P L + ++ V V D+NDN P+ + F V + +P V Sbjct: 529 ALTLQARDHGSPTLSANVSLRVLVGDRNDNAPRVLYPALGPDGSAFFDMVPRSAEPGYLV 588 Query: 659 GMVTVMDADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVD 716 V +DAD G NA +S ++ + + +FS+ TG + + + V D Sbjct: 589 TKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRD 648 Query: 717 GGDPPRSATATVSLFVMD 734 GG PP SATAT+ L D Sbjct: 649 GGQPPLSATATLHLVFAD 666 Score = 228 bits (581), Expect = 2e-59 Identities = 171/660 (25%), Positives = 310/660 (46%), Gaps = 54/660 (8%) Query: 260 LIVKGALDREQ--RDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317 L+VK +DREQ ++ L++ + P + ++ V+I DVND++P+F+K ++ Sbjct: 84 LLVKNRIDREQICKERRRCELQLEAVVENPLNIFHVI-VVIEDVNDHAPQFDKKEIHLEI 142 Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW---LSVLHRID 374 E+++ GT + A D D+ +N +Y + ++R++ G LS+ +D Sbjct: 143 FESASAGTRLSLDPATDPDININSIKDYKINS-NPYFSLMVRVNSDGGKYPELSLEKLLD 201 Query: 375 REEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAE 434 REE + A D G PP++ A + +++KD NDN P + R RI L +E Sbjct: 202 REEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDN-PPVFSRDEYRISL-------SE 253 Query: 435 DVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEG--DQNKKKYFLHTSTP 492 ++ +P+ V +D+D+G N + + A T+ ++K + + Sbjct: 254 NLPPGSPVLQVTATDQDEGVNAEINY-------YFRSTAQSTKHMFSLDEKTGMIKNNQS 306 Query: 493 LDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGE 552 D+E + + + A D G LS+ +I+++ D NDN P + + EN+ PG Sbjct: 307 FDFEDVERYTMEVEAKDGGG--LSTQCKVIIEILDENDNSPEIIITSLSDQILENSPPGM 364 Query: 553 RVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFKVNA 611 VA D D G N E+ ++++ + I++ + ++ + LDREQT Y + A Sbjct: 365 VVALFKTRDLDFGGNGEVRCNIETDIPFKIYSSSNNYYKLVTDGALDREQTPEYNVTIVA 424 Query: 612 KDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRN 671 D+G P L S ++ + VAD NDN P F Q + +V EN P + + V+ D D G N Sbjct: 425 TDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPGASIAQVSASDPDLGLN 484 Query: 672 AEMSLYIEENN-------NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSA 724 +S I ++ + S+ +G +++ +FD E + ++A D G P SA Sbjct: 485 GHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGSPTLSA 544 Query: 725 TATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGINADL 779 ++ + V D NDNAP V P + + ++P S+ +V V+A D+D G NA L Sbjct: 545 NVSLRVLVGDRNDNAPRVLYPALGPDGSAFFDMVPRSAEPGYLVTKVVAVDADSGHNAWL 604 Query: 780 NYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFV 839 +Y ++ + LF + +G V L + RL+V V D GQP S T +H+ Sbjct: 605 SYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVF 664 Query: 840 NESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVV 899 +++ + D++ P + L + V +++V+ ++ +++ Sbjct: 665 ADNLQE---------------ILPDLSDRPVLSDPQAELQFYLVVALALISVLFLLAVIL 709 Score = 192 bits (489), Expect = 1e-48 Identities = 146/503 (29%), Positives = 230/503 (45%), Gaps = 30/503 (5%) Query: 360 LDETSGWLSVLHRIDREEV-NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIR 418 +D SG L V +RIDRE++ + R + + + V++ I+D ND+ P + + Sbjct: 77 VDAESGDLLVKNRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFDKK 136 Query: 419 KIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEG 478 +I + E T ++L +D D N + + + F L +++G Sbjct: 137 EIH--------LEIFESASAGTRLSLDPATDPDININSIKDYKINSNPYFSLMVRVNSDG 188 Query: 479 DQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQS 538 + + L LD E R ++++ A+D G P S+ + + V DTNDNPP+F + Sbjct: 189 GKYPE---LSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRD 245 Query: 539 VVEVYFPENNIPGERVATVLATDADSGKNAEIAY---SLDSSVMGIFAIDPDSGDILVNT 595 + EN PG V V ATD D G NAEI Y S S +F++D +G I N Sbjct: 246 EYRISLSENLPPGSPVLQVTATDQDEGVNAEINYYFRSTAQSTKHMFSLDEKTGMIKNNQ 305 Query: 596 VLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPN 655 D E +RY +V AKD G L VI+++ D+NDN P+ + + + EN P Sbjct: 306 SFDFEDVERYTMEVEAKDGG--GLSTQCKVIIEILDENDNSPEIIITSLSDQILENSPPG 363 Query: 656 SPVGMVTVMDADKGRNAEMSLYIEEN--NNIFSIENDTGTIYSTMSFDREHQTTYTFRVK 713 V + D D G N E+ IE + I+S N+ + + + DRE Y + Sbjct: 364 MVVALFKTRDLDFGGNGEVRCNIETDIPFKIYSSSNNYYKLVTDGALDREQTPEYNVTIV 423 Query: 714 AVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTL--LPPSSNVRTVVATVLATDS 771 A D G PP S++ +++L+V D NDNAP + + PP ++ +A V A+D Sbjct: 424 ATDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPGAS----IAQVSASDP 479 Query: 772 DDGINADLNYSIVGGNPFKL-----FEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQ 826 D G+N ++YSIV + L + SGVV + L +Q D G Sbjct: 480 DLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGS 539 Query: 827 PSQSTTTLVHVFVNESVSNATAI 849 P+ S + V V + NA + Sbjct: 540 PTLSANVSLRVLVGDRNDNAPRV 562 Score = 98.6 bits (244), Expect = 3e-20 Identities = 80/277 (28%), Positives = 131/277 (47%), Gaps = 35/277 (12%) Query: 582 FAIDPDSGDILVNTVLDREQT----DRYEFKVNAK-DKGIPVLQGSTTVIVQVADKNDND 636 F++D +SGD+LV +DREQ R E ++ A + + + VIV + D ND+ Sbjct: 75 FSVDAESGDLLVKNRIDREQICKERRRCELQLEAVVENPLNIFH----VIVVIEDVNDHA 130 Query: 637 PKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIE---NDTGT 693 P+F + + E+ + + + D D N+ + Y +N FS+ N G Sbjct: 131 PQFDKKEIHLEIFESASAGTRLSLDPATDPDININS-IKDYKINSNPYFSLMVRVNSDGG 189 Query: 694 IYSTMSF----DREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-------V 742 Y +S DRE Q +++ + A+DGGDPPRSATA + + V D NDN P + Sbjct: 190 KYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYRI 249 Query: 743 TLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSI--VGGNPFKLFEIDPTSGV 800 +L +N LPP S V V ATD D+G+NA++NY + +F +D +G+ Sbjct: 250 SLSEN-----LPPGS----PVLQVTATDQDEGVNAEINYYFRSTAQSTKHMFSLDEKTGM 300 Query: 801 VSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837 + + + + V+ D G S ++ + Sbjct: 301 IKNNQSFDFEDVERYTMEVEAKDGGGLSTQCKVIIEI 337 >gi|16933557 dachsous 1 precursor [Homo sapiens] Length = 3298 Score = 320 bits (819), Expect = 6e-87 Identities = 248/805 (30%), Positives = 371/805 (46%), Gaps = 98/805 (12%) Query: 34 LRYRLAEEGPADVRIGNVASDLGIVTGSGEVTF-SLESGSEY---LKIDNLTGELSTSER 89 L ++ EE PA IG++++ L T + + F S + GS L ID +G + T+ R Sbjct: 47 LDLQIDEEQPAGTLIGDISAGLPAGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTA-R 105 Query: 90 RIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLT 149 +DRE+ + + + + P + V++ V V DIND+ P FP Sbjct: 106 VLDREQRDR-------------YRFTAVTPDGATVEV---TVRVADINDHAPAFPQARAA 149 Query: 150 LTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGG 209 L V E+ GT Y L A D D GR G + Y L Sbjct: 150 LQVPEHTAFGTRYPLEPARDADAGRLGTQGYAL--------------------------- 182 Query: 210 GGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDRE 269 SG G+G F L+ PDG P+L+V G LDRE Sbjct: 183 -----SGDGAG---------------------ETFRLETRPGPDGTPVPELVVTGELDRE 216 Query: 270 QRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQ 329 R Y L L DGG PPR +QA+L V + D+ND++P F +S Y A ++E+ APG+P+LQ Sbjct: 217 NRSHYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQ 276 Query: 330 LRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARD 389 + A+D D GVNG + Y +D +G L + +D E+ V ARD Sbjct: 277 VFASDADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQARD 336 Query: 390 RGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSD 449 G P+ A V ++++D NDN PS+ + + DG V+E +A + VSD Sbjct: 337 GGAHPELGSAFVTVHVRDANDNQPSMTVIFLS----ADGSPQVSEAAPPGQLVARISVSD 392 Query: 450 RDQGENGVVTCTVV-GDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAV 508 D G+ V ++ G+ F L Q+ Y + + LD E +N+ + A Sbjct: 393 PDDGDFAHVNVSLEGGEGHFAL-------STQDSVIYLVCVARRLDREERDAYNLRVTAT 445 Query: 509 DSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVY-FPENNIPGERVATVLATDADSGKN 567 DSGSP L + + ++ V D NDN P F + + PE +PG V V A D D G N Sbjct: 446 DSGSPPLRAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTN 505 Query: 568 AEIAYSL-DSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626 ++ YSL + F+IDP SG I LD E + + V A D G+P L S TV Sbjct: 506 GQVTYSLAPGAHTHWFSIDPTSGIITTAASLDYELEPQPQLIVVATDGGLPPLASSATVS 565 Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYI-----EEN 681 V + D NDN+P+F + + + E QP + VT DAD G +S + Sbjct: 566 VALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSG 625 Query: 682 NNIFSIENDTGTIYSTMSFDREH-QTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAP 740 + F I+ +G + +T + DR+ +++ F V AVDGG + V +F+ DENDN P Sbjct: 626 SPPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGGG--LKSMVYVKVFLSDENDNPP 683 Query: 741 TVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGV 800 P+ + + + S T V + A D D G + L+Y I+ GN LF +D SG+ Sbjct: 684 QF-YPREYAAS-ISAQSPPGTAVLRLRAHDPDQGSHGRLSYHILAGNSPPLFTLDEQSGL 741 Query: 801 VSLVGKLTQKHYGLHRLVVQVNDSG 825 +++ L ++ + +L + D G Sbjct: 742 LTVAWPLARRANSVVQLEIGAEDGG 766 Score = 250 bits (639), Expect = 4e-66 Identities = 252/870 (28%), Positives = 374/870 (42%), Gaps = 138/870 (15%) Query: 41 EGPADVRIGNVASDLGI----VTGSGEVTFSLESGSE-YLKIDNLTGELSTSERRIDREK 95 E P DV G + L +G VT+ L +G+ ++ +GEL T+ +DRE+ Sbjct: 1863 EVPEDVPAGTLLLQLQAHDPDAGANGHVTYYLGAGTAGAFLLEPSSGELRTAAA-LDREQ 1921 Query: 96 LPQCQMIFDENECFLDFEVSVI-----GPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTL 150 P F VS + GP + V + + V D+ND+ PTFP+ L L Sbjct: 1922 CPS-----------YTFSVSAVDGAAAGPLSTTVSV---TITVRDVNDHAPTFPTSPLRL 1967 Query: 151 TVEENRPVGTLYLLPTAT----DRDFGRNGIERYELLQEPGGGGS----GGESRRA---- 198 + P + L AT DRD G N Y L P G + GE R A Sbjct: 1968 RLPRPGPSFSTPTLALATLRAEDRDAGANASILYRLAGTPPPGTTVDSYTGEIRVARSPV 2027 Query: 199 --GAADSAPYP-----GGGGNGASG----GGSGGSKR-------------RLDASEG--- 231 G D + G A+G G G ++R R +A G Sbjct: 2028 ALGPRDRVLFIVATDLGRPARSATGVIIVGLQGEAERGPRFPRASSEATIRENAPPGTPI 2087 Query: 232 -------GGGTN--------PGGRSSVFELQVADTPDGEKQPQLIVKGALDREQRDSYEL 276 GGTN G F +Q + + + LD E L Sbjct: 2088 VSPRAVHAGGTNGPITYSILSGNEKGTFSIQPSTGAITVRSAE-----GLDFEVSPRLRL 2142 Query: 277 TLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLD 336 L+ GG + +L + + D NDN+PRF + Y A L E+ P+LQ+ A DLD Sbjct: 2143 VLQAESGG---AFAFTVLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVEADDLD 2199 Query: 337 VGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKT 396 G GQI Y AA++ R L +D T+G ++ +DRE + R +MA DRG P Sbjct: 2200 QGSGGQISYSL-AASQPARGLFHVDPTTGTITTTAILDREIWAETRLVLMATDRGSPALV 2258 Query: 397 DKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENG 456 AT+ + + D NDN P+I + V+ED L+ + IA V +D D G Sbjct: 2259 GSATLTVMVIDTNDNRPTIP---------QPWELRVSEDALLGSEIAQVTGNDVDSGP-- 2307 Query: 457 VVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTST--PLDYEATREFNVVIVAVDSGSPS 514 V + + S + + +Y S PLD+E + + ++A D Sbjct: 2308 ---------VLWYVLSPSGPQDPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHDGPHEG 2358 Query: 515 LSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSL 574 ++ L V V D NDN P F QS+ +V E+ PG + +V ATD DSG N I+Y L Sbjct: 2359 RAN---LTVLVEDVNDNAPAFSQSLYQVMLLEHTPPGSAILSVSATDRDSGANGHISYHL 2415 Query: 575 DSSVMGIFAIDPDSGDI--LVNTV-LDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVAD 631 S G F++DP++G + +V TV L + + + + A+D G P TV VQ+ D Sbjct: 2416 ASPADG-FSVDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDHGAPGRAARATVHVQLQD 2474 Query: 632 KNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRN---AEMSLYIEENNNIFSIE 688 +ND+ P F + V E+L P S + + DAD R+ + S+ +F +E Sbjct: 2475 QNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEATDADGSRSHAAVDYSIISGNWGRVFQLE 2534 Query: 689 --------------NDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMD 734 G + D E T Y V A D G PP+S+ V++ V+D Sbjct: 2535 PRLAEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADRGQPPQSSVVPVTVTVLD 2594 Query: 735 ENDNAPTVTLPKNISYTL-LPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFE 793 NDN P T SY + +P + V + V A+D+D G + + +++ G+P LFE Sbjct: 2595 VNDNPPVFT---RASYRVTVPEDTPVGAELLHVEASDADPGPHGLVRFTVSSGDPSGLFE 2651 Query: 794 IDPTSGVVSLVGKLTQKHYGLHRLVVQVND 823 +D +SG + L L + H+LVVQ D Sbjct: 2652 LDESSGTLRLAHALDCETQARHQLVVQAAD 2681 Score = 242 bits (618), Expect = 1e-63 Identities = 214/741 (28%), Positives = 313/741 (42%), Gaps = 112/741 (15%) Query: 75 LKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVL 134 L++D TG LS + R +DRE P ++ + + S+ +V V Sbjct: 1486 LRLDARTGALS-APRGLDRETTPALLLLVEATD-------RPANASRRRAARVSARVFVT 1537 Query: 135 DINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGE 194 D NDN P F SP + + E++P G L A D D G Y L Sbjct: 1538 DENDNAPVFASPS-RVRLPEDQPPGPAALHVVARDPDLGEAARVSYRL------------ 1584 Query: 195 SRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDG 254 + GG G RL +S G Sbjct: 1585 --------------------ASGGDGHF--RLHSSTGA---------------------- 1600 Query: 255 EKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYE 314 L V LDREQR + LT+ D G PPRS+ +L V + DVND +P F++ Y Sbjct: 1601 -----LSVVRPLDREQRAEHVLTVVASDHGSPPRSATQVLTVSVADVNDEAPTFQQQEYS 1655 Query: 315 ADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRID 374 L EN+ PGT +L LRA D DVG NGQ+ Y G ++ES LD +G L+ L +D Sbjct: 1656 VLLRENNPPGTSLLTLRATDPDVGANGQVTY-GGVSSES----FSLDPDTGVLTTLRALD 1710 Query: 375 REEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAE 434 REE ++ TV A+DRG PP+ TV + ++DEND+ P+ G A+++ Sbjct: 1711 REEQEEINLTVYAQDRGSPPQLTHVTVRVAVEDENDHAPTF------------GSAHLSL 1758 Query: 435 DV---LVDTPIALVQVSDRDQGENGVVTCTVVGDVP---FQLKPASDTEGDQNKKKYFLH 488 +V + +++ SD D G NG + ++ P F L AS G Sbjct: 1759 EVPEGQDPQTLTMLRASDPDVGANGQLQYRILDGDPSGAFVLDLASGEFG---------- 1808 Query: 489 TSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENN 548 T PLD E F + I A D G P+LS+ L V V D ND+ P F V PE+ Sbjct: 1809 TMRPLDREVEPAFQLRIEARDGGQPALSATLLLTVTVLDANDHAPAFPVPAYSVEVPEDV 1868 Query: 549 IPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFK 608 G + + A D D+G N + Y L + G F ++P SG++ LDREQ Y F Sbjct: 1869 PAGTLLLQLQAHDPDAGANGHVTYYLGAGTAGAFLLEPSSGELRTAAALDREQCPSYTFS 1928 Query: 609 VNAKD-KGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKEN----LQPNSPVGMVTV 663 V+A D L + +V + V D ND+ P F + P + + Sbjct: 1929 VSAVDGAAAGPLSTTVSVTITVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTLALATLRA 1988 Query: 664 MDADKGRNAEMSLYIEENNNI-FSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPR 722 D D G NA + + ++++ TG I S + A D G P R Sbjct: 1989 EDRDAGANASILYRLAGTPPPGTTVDSYTGEIRVARSPVALGPRDRVLFIVATDLGRPAR 2048 Query: 723 SATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYS 782 SAT + + + E + P P+ S + ++ T + + A + G N + YS Sbjct: 2049 SATGVIIVGLQGEAERGP--RFPRASSEATIRENAPPGTPIVSPRAVHA-GGTNGPITYS 2105 Query: 783 IVGGNPFKLFEIDPTSGVVSL 803 I+ GN F I P++G +++ Sbjct: 2106 ILSGNEKGTFSIQPSTGAITV 2126 Score = 228 bits (582), Expect = 2e-59 Identities = 217/795 (27%), Positives = 328/795 (41%), Gaps = 100/795 (12%) Query: 61 SGEVTFSLESGSE--YLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIG 118 +G+VT+SL G+ + ID +G ++T+ +D E PQ Q+I V+ G Sbjct: 505 NGQVTYSLAPGAHTHWFSIDPTSGIITTAAS-LDYELEPQPQLIV----------VATDG 553 Query: 119 PSQSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIE 178 V + D+NDN P F ++ E GT +L TATD D G G+ Sbjct: 554 GLPPLASSATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLL 613 Query: 179 RYELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPG 238 Y L GA G SG R+DA G Sbjct: 614 SYSL------------------------------GAGLGSSGSPPFRIDAHSG------- 636 Query: 239 GRSSVFELQVADTPDGEKQPQLIVKGALDREQR-DSYELTLRVRDGGDPPRSSQAILRVL 297 + LDR+Q S++ T+ DGG S ++V Sbjct: 637 --------------------DVCTTRTLDRDQGPSSFDFTVTAVDGGG--LKSMVYVKVF 674 Query: 298 ITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRL 357 ++D NDN P+F Y A ++ S PGT +L+LRA D D G +G++ Y A L Sbjct: 675 LSDENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHILAGNSPP--L 732 Query: 358 LRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEI 417 LDE SG L+V + R + ++ + A D G A V ++I P E Sbjct: 733 FTLDEQSGLLTVAWPLARRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPTPPIFEQ 792 Query: 418 RKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTE 477 + V +V EDV T + +VQ + G VT ++ G P L Sbjct: 793 LQY--------VFSVPEDVAPGTSVGIVQAHN-PPGRLAPVTLSLSGGDPRGLFSLDAVS 843 Query: 478 GDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQ 537 G L T PLD E + V SG P + + V + D NDN P F Sbjct: 844 G-------LLQTLRPLDRELLGPVLELEVRAGSGVPPAFAVARVRVLLDDVNDNSPAFPA 896 Query: 538 SVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVL 597 V P N PG + T+ A D DSG N+ + ++L + G F +DP +G + + L Sbjct: 897 PEDTVLLPPNTAPGTPIYTLRALDPDSGVNSRVTFTLLAGGGGAFTVDPTTGHVRLMRPL 956 Query: 598 DREQTDRYEFKVNAKDKGIP--VLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPN 655 +E ++ A+D G P V+VQ P+F + + Sbjct: 957 GPSGGPAHELELEARDGGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRVDLPSGTTAG 1016 Query: 656 SPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAV 715 + V V D G L E ++ F +E +G ++ + DRE Q Y +V AV Sbjct: 1017 TQVLQVQAQAPD-GGPITYHLAAEGASSPFGLEPQSGWLWVRAALDREAQELYILKVMAV 1075 Query: 716 DGGDP---PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSD 772 G ++ TATV + ++++N+++P L ++ ++ + + T V V ATD D Sbjct: 1076 SGSKAELGQQTGTATVRVSILNQNEHSP--RLSEDPTFLAVAENQPPGTSVGRVFATDRD 1133 Query: 773 DGINADLNYSIVG-GNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQST 831 G N L YS+ K F I P +G V+ + L ++ ++L+VQV D G P +ST Sbjct: 1134 SGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGGSPPRST 1193 Query: 832 TTLVHVFVNESVSNA 846 T VHV V + N+ Sbjct: 1194 TGTVHVAVLDLNDNS 1208 Score = 226 bits (576), Expect = 9e-59 Identities = 237/859 (27%), Positives = 362/859 (42%), Gaps = 122/859 (14%) Query: 58 VTGSGEVTFSLESG--SEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVS 115 V +G++ + + G S +D +GE T R +DRE P Q+ + + Sbjct: 1779 VGANGQLQYRILDGDPSGAFVLDLASGEFGTM-RPLDREVEPAFQLRIEARD-------- 1829 Query: 116 VIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRN 175 G + V VLD ND+ P FP P ++ V E+ P GTL L A D D G N Sbjct: 1830 --GGQPALSATLLLTVTVLDANDHAPAFPVPAYSVEVPEDVPAGTLLLQLQAHDPDAGAN 1887 Query: 176 GIERYELLQEPGGG----GSGGESRRAGAADSAPYPG-----GGGNGASGGGSGGSKRRL 226 G Y L G S GE R A A D P +GA+ G + Sbjct: 1888 GHVTYYLGAGTAGAFLLEPSSGELRTAAALDREQCPSYTFSVSAVDGAAAGPLSTTVSVT 1947 Query: 227 DASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQRD-------------- 272 P +S L++ P L + L E RD Sbjct: 1948 ITVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTLAL-ATLRAEDRDAGANASILYRLAGT 2006 Query: 273 --------SYELTLRVR------------------DGGDPPRSSQAILRVLITDVNDNSP 306 SY +RV D G P RS+ ++ V + + P Sbjct: 2007 PPPGTTVDSYTGEIRVARSPVALGPRDRVLFIVATDLGRPARSATGVIIVGLQGEAERGP 2066 Query: 307 RFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW 366 RF ++ EA + EN+ PGTPI+ RA G NG I Y + E + + ++G Sbjct: 2067 RFPRASSEATIRENAPPGTPIVSPRAVHAG-GTNGPITYSILSGNE--KGTFSIQPSTGA 2123 Query: 367 LSV--LHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIP 424 ++V +D E +LR + A G T + L ++D NDN P R Sbjct: 2124 ITVRSAEGLDFEVSPRLRLVLQAESGGAFAFT---VLTLTLQDANDNAP--------RFL 2172 Query: 425 LKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVP----FQLKPASDTEGDQ 480 VA + E ++ P+ V+ D DQG G ++ ++ P F + P + T Sbjct: 2173 RPHYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAASQPARGLFHVDPTTGT---- 2228 Query: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540 + T+ LD E E +V++A D GSP+L + +L V V DTNDN P Q Sbjct: 2229 ------ITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNRPTIPQPW- 2281 Query: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600 E+ E+ + G +A V D DSG S S F++ G + + LD E Sbjct: 2282 ELRVSEDALLGSEIAQVTGNDVDSGPVLWYVLS-PSGPQDPFSVGRYGGRVSLTGPLDFE 2340 Query: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660 Q DRY+ ++ A D +G + V V D NDN P F Q ++ + E+ P S + Sbjct: 2341 QCDRYQLQLLAHDGPH---EGRANLTVLVEDVNDNAPAFSQSLYQVMLLEHTPPGSAILS 2397 Query: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYS---TMSFDREHQTTYTFRVKAVDG 717 V+ D D G N +S ++ + FS++ + GT+++ T++ + ++A D Sbjct: 2398 VSATDRDSGANGHISYHLASPADGFSVDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDH 2457 Query: 718 GDPPRSATATVSLFVMDENDNAPTVTLPK-NISYTL-LPPSSNVRTVVATVLATDSDDG- 774 G P R+A ATV + + D+ND+AP+ TL ++ T LPP S + T+ AT D+D Sbjct: 2458 GAPGRAARATVHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEAT----DADGSR 2513 Query: 775 INADLNYSIVGGNPFKLFEIDP--------------TSGVVSLVGKLTQKHYGLHRLVVQ 820 +A ++YSI+ GN ++F+++P G + L+ L + + L V Sbjct: 2514 SHAAVDYSIISGNWGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVA 2573 Query: 821 VNDSGQPSQSTTTLVHVFV 839 D GQP QS+ V V V Sbjct: 2574 AADRGQPPQSSVVPVTVTV 2592 Score = 218 bits (554), Expect = 3e-56 Identities = 227/833 (27%), Positives = 343/833 (41%), Gaps = 124/833 (14%) Query: 35 RYRLAEE---GPADVRIGNVASDLGIVTGSGEVTFSLESGSE-YLKIDNLTGELSTSERR 90 R RL E+ GPA + + DLG + V++ L SG + + ++ + TG LS R Sbjct: 1551 RVRLPEDQPPGPAALHVVARDPDLG---EAARVSYRLASGGDGHFRLHSSTGALSVV-RP 1606 Query: 91 IDREKLPQCQMIFDENECFLDFEVSVIG-PSQSWVDLFEGQVIVLDINDNTPTFPSPVLT 149 +DRE+ E L S G P +S + V V D+ND PTF + Sbjct: 1607 LDREQ---------RAEHVLTVVASDHGSPPRSATQVLT--VSVADVNDEAPTFQQQEYS 1655 Query: 150 LTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGG 209 + + EN P GT L ATD D G NG Y Sbjct: 1656 VLLRENNPPGTSLLTLRATDPDVGANGQVTY----------------------------- 1686 Query: 210 GGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDRE 269 GG LD G L D E+Q ++ Sbjct: 1687 -------GGVSSESFSLDPDTG-------------VLTTLRALDREEQEEI--------- 1717 Query: 270 QRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQ 329 LT+ +D G PP+ + +RV + D ND++P F + ++ E P T + Sbjct: 1718 -----NLTVYAQDRGSPPQLTHVTVRVAVEDENDHAPTFGSAHLSLEVPEGQDPQT-LTM 1771 Query: 330 LRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARD 389 LRA+D DVG NGQ++Y S LD SG + +DRE + + ARD Sbjct: 1772 LRASDPDVGANGQLQYRILDGDPS--GAFVLDLASGEFGTMRPLDREVEPAFQLRIEARD 1829 Query: 390 RGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSD 449 GQP + + + + D ND+ P+ P+ V EDV T + +Q D Sbjct: 1830 GGQPALSATLLLTVTVLDANDHAPA--------FPVPAYSVEVPEDVPAGTLLLQLQAHD 1881 Query: 450 RDQGENGVVTCTVVGDV--PFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVA 507 D G NG VT + F L+P+S L T+ LD E + + A Sbjct: 1882 PDAGANGHVTYYLGAGTAGAFLLEPSSGE----------LRTAAALDREQCPSYTFSVSA 1931 Query: 508 VDSGSPS-LSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPEN----NIPGERVATVLATDA 562 VD + LS+ S+ + V D ND+ P F S + + P + P +AT+ A D Sbjct: 1932 VDGAAAGPLSTTVSVTITVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTLALATLRAEDR 1991 Query: 563 DSGKNAEIAYSLDSSVMGIFAIDPDSGDILV-NTVLDREQTDRYEFKVNAKDKGIPVLQG 621 D+G NA I Y L + +D +G+I V + + DR F V A D G P Sbjct: 1992 DAGANASILYRLAGTPPPGTTVDSYTGEIRVARSPVALGPRDRVLFIV-ATDLGRPARSA 2050 Query: 622 STTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEEN 681 + +IV + + + P+F + ++EN P +P+ + A G N ++ I Sbjct: 2051 TGVIIVGLQGEAERGPRFPRASSEATIRENAPPGTPIVSPRAVHAG-GTNGPITYSILSG 2109 Query: 682 N--NIFSIENDTG--TIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDEND 737 N FSI+ TG T+ S D E ++A GG A ++L + D ND Sbjct: 2110 NEKGTFSIQPSTGAITVRSAEGLDFEVSPRLRLVLQAESGG---AFAFTVLTLTLQDAND 2166 Query: 738 NAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFK-LFEIDP 796 NAP P +++ LP S + + V A D D G ++YS+ P + LF +DP Sbjct: 2167 NAPRFLRPHYVAF--LPESRPLEGPLLQVEADDLDQGSGGQISYSLAASQPARGLFHVDP 2224 Query: 797 TSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAI 849 T+G ++ L ++ + RLV+ D G P+ + + V V ++ N I Sbjct: 2225 TTGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNRPTI 2277 Score = 216 bits (550), Expect = 9e-56 Identities = 167/580 (28%), Positives = 274/580 (47%), Gaps = 50/580 (8%) Query: 251 TPDGEKQP--------QLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVN 302 +P G + P ++ + G LD EQ D Y+L L DG P +A L VL+ DVN Sbjct: 2314 SPSGPQDPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHDG---PHEGRANLTVLVEDVN 2370 Query: 303 DNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDE 362 DN+P F +S+Y+ L E++ PG+ IL + A D D G NG I Y + + +D Sbjct: 2371 DNAPAFSQSLYQVMLLEHTPPGSAILSVSATDRDSGANGHISYHLASPADG----FSVDP 2426 Query: 363 TSGWLSVLH---RIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRK 419 +G L + + + + + ARD G P + +ATV + ++D+ND+ PS + Sbjct: 2427 NNGTLFTIVGTVALGHDGSGAVDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLSH 2486 Query: 420 IGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGEN-GVVTCTVV----GDVPFQLKP-- 472 V ED+ + + ++ +D D + V +++ G V FQL+P Sbjct: 2487 YR--------VAVTEDLPPGSTLLTLEATDADGSRSHAAVDYSIISGNWGRV-FQLEPRL 2537 Query: 473 --ASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTND 530 A ++ G + L PLD+E+ ++N+ + A D G P SS + V V D ND Sbjct: 2538 AEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADRGQPPQSSVVPVTVTVLDVND 2597 Query: 531 NPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDS-SVMGIFAIDPDSG 589 NPP+F ++ V PE+ G + V A+DAD G + + +++ S G+F +D SG Sbjct: 2598 NPPVFTRASYRVTVPEDTPVGAELLHVEASDADPGPHGLVRFTVSSGDPSGLFELDESSG 2657 Query: 590 DILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVK 649 + + LD E R++ V A D V ++V D ND+ P F ++ + V Sbjct: 2658 TLRLAHALDCETQARHQLVVQAADPA-GAHFALAPVTIEVQDVNDHGPAFPLNLLSTSVA 2716 Query: 650 ENLQPNSPVGMVTVMDADKGRNAEMSLYI------EENNNIFSIENDTGTIYSTMSFDRE 703 EN P + V + +D D G + + E F++ + TG + + + FD E Sbjct: 2717 ENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEGREAFALNSSTGELRARVPFDYE 2776 Query: 704 HQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVV 763 H ++ V A D G+ SA+ TVS+ V E++ P P + +P + + Sbjct: 2777 HTESFRLLVGAADAGN--LSASVTVSVLVTGEDEYDPVFLAP--AFHFQVPEGARRGHSL 2832 Query: 764 ATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSL 803 V ATD D G + + YS+ +P+ F I+ T+G + L Sbjct: 2833 GHVQATDEDGGADGLVLYSLATSSPY--FGINQTTGALYL 2870 Score = 202 bits (513), Expect = 2e-51 Identities = 236/849 (27%), Positives = 344/849 (40%), Gaps = 123/849 (14%) Query: 38 LAEEGPADVRIGNVASDLGIVTGSGEVTFSLESGSEYLK---IDNLTGELSTSERRIDRE 94 +AE P +G V + +G +T+SL+ SE K I TGE++T + +DRE Sbjct: 1114 VAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQT-LDRE 1172 Query: 95 KLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTF------PSPVL 148 + Q++ + G S V VLD+NDN+PTF L Sbjct: 1173 QQSSYQLLVQVQD----------GGSPPRSTTGTVHVAVLDLNDNSPTFLQASGAAGGGL 1222 Query: 149 TLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPG 208 + V + P GTL A D D G NG Y L Sbjct: 1223 PIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTL-------------------------- 1256 Query: 209 GGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDR 268 T PG S +F L GE L+ L R Sbjct: 1257 --------------------------TGPG--SELFSLH---PHSGE----LLTAAPLIR 1281 Query: 269 EQRDSYELTLRVRDGGDPPRSS--QAILRVLIT--------DVNDNSPRFE-KSVYEADL 317 +R Y LTL D G PPRS+ Q +++VL + D+ + P V Sbjct: 1282 AERPHYVLTLSAHDQGSPPRSASLQLLVQVLPSARLAEPPPDLAERDPAAPVPVVLTVTA 1341 Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEY--VFGAATESVRRLLRLDETSGWLSVLHRIDR 375 AE PG+ +L AA GV G + Y V GA E LD SG L + +D Sbjct: 1342 AEGLRPGS-LLGSVAAPEPAGV-GALTYTLVGGADPEGT---FALDAASGRLYLARPLDF 1396 Query: 376 EEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAED 435 E R + + V + ++DEN++ P+ R PL + E+ Sbjct: 1397 EAGPPWRALTVRAEGPGGAGARLLRVQVQVQDENEHAPA-----FARDPL---ALALPEN 1448 Query: 436 VLVDTPIALVQVSDRD-QGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLD 494 + + SD D G N V ++ P P D + L LD Sbjct: 1449 PEPGAALYTFRASDADGPGPNSDVRYRLLRQEP----PVPALRLD--ARTGALSAPRGLD 1502 Query: 495 YEATREFNVVIVAVD---SGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPG 551 E T +++ A D + S ++ S V V D NDN P+F S V PE+ PG Sbjct: 1503 RETTPALLLLVEATDRPANASRRRAARVSARVFVTDENDNAPVFA-SPSRVRLPEDQPPG 1561 Query: 552 ERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNA 611 V+A D D G+ A ++Y L S G F + +G + V LDREQ + V A Sbjct: 1562 PAALHVVARDPDLGEAARVSYRLASGGDGHFRLHSSTGALSVVRPLDREQRAEHVLTVVA 1621 Query: 612 KDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRN 671 D G P + + V VAD ND P F Q ++ ++EN P + + + D D G N Sbjct: 1622 SDHGSPPRSATQVLTVSVADVNDEAPTFQQQEYSVLLRENNPPGTSLLTLRATDPDVGAN 1681 Query: 672 AEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLF 731 +++ Y ++ FS++ DTG + + + DRE Q V A D G PP+ TV + Sbjct: 1682 GQVT-YGGVSSESFSLDPDTGVLTTLRALDREEQEEINLTVYAQDRGSPPQLTHVTVRVA 1740 Query: 732 VMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKL 791 V DEND+APT + +L P + + A+D D G N L Y I+ G+P Sbjct: 1741 VEDENDHAPTF---GSAHLSLEVPEGQDPQTLTMLRASDPDVGANGQLQYRILDGDPSGA 1797 Query: 792 FEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDS 851 F +D SG + L ++ +L ++ D GQP+ S T L+ V V ++ +A A Sbjct: 1798 FVLDLASGEFGTMRPLDREVEPAFQLRIEARDGGQPALSATLLLTVTVLDANDHAPAFPV 1857 Query: 852 QIARSLHIP 860 A S+ +P Sbjct: 1858 P-AYSVEVP 1865 Score = 188 bits (478), Expect = 2e-47 Identities = 161/547 (29%), Positives = 225/547 (41%), Gaps = 35/547 (6%) Query: 314 EADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATES-VRRLLRLDETSGWLSVLHR 372 + + E GT I + +A L G + Y A S V L +DE SG + Sbjct: 48 DLQIDEEQPAGTLIGDI-SAGLPAGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTARV 106 Query: 373 IDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANV 432 +DRE+ ++ RFT + D V + + D ND+ P+ P V Sbjct: 107 LDREQRDRYRFTAVTPDGAT------VEVTVRVADINDHAPAF--------PQARAALQV 152 Query: 433 AEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTP 492 E T L D D G G + GD + G L + Sbjct: 153 PEHTAFGTRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPELVVTGE 212 Query: 493 LDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGE 552 LD E + + + A D GSP + L V + D ND+ P F QS E+ PG Sbjct: 213 LDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGS 272 Query: 553 RVATVLATDADSGKNAEIAYSLD---SSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKV 609 V V A+DAD+G N + Y ++ S G F+ID +G + + LD EQ +E V Sbjct: 273 PVLQVFASDADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVV 332 Query: 610 NAKDKGIPVLQGSTTVIVQVADKNDNDPK----FMQDVFTFYVKENLQPNSPVGMVTVMD 665 A+D G GS V V V D NDN P F+ + V E P V ++V D Sbjct: 333 QARDGGAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVSD 392 Query: 666 ADKGRNAEMSLYIEENNNIFSIENDTGTIYSTM---SFDREHQTTYTFRVKAVDGGDPPR 722 D G A +++ +E F++ IY DRE + Y RV A D G PP Sbjct: 393 PDDGDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARRLDREERDAYNLRVTATDSGSPPL 452 Query: 723 SATATVSLFVMDENDNAPT----VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINAD 778 A A L V D NDNAP + P+ + LP S VR V A D D G N Sbjct: 453 RAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVR-----VTARDPDQGTNGQ 507 Query: 779 LNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVF 838 + YS+ G F IDPTSG+++ L + +L+V D G P +++ V V Sbjct: 508 VTYSLAPGAHTHWFSIDPTSGIITTAASLDYELEPQPQLIVVATDGGLPPLASSATVSVA 567 Query: 839 VNESVSN 845 + + N Sbjct: 568 LQDVNDN 574 Score = 185 bits (470), Expect = 2e-46 Identities = 210/827 (25%), Positives = 324/827 (39%), Gaps = 141/827 (17%) Query: 64 VTFSLESGSE--YLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQ 121 VT SL G +D ++G L T R +DRE L L+ EV Sbjct: 824 VTLSLSGGDPRGLFSLDAVSGLLQTL-RPLDRELLGPV----------LELEVRAGSGVP 872 Query: 122 SWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYE 181 + +V++ D+NDN+P FP+P T+ + N GT A D D G N + Sbjct: 873 PAFAVARVRVLLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIYTLRALDPDSGVNSRVTFT 932 Query: 182 LLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRS 241 LL GGG + + G R + GG Sbjct: 933 LL------------------------AGGGGAFTVDPTTGHVRLMRPLGPSGGP------ 962 Query: 242 SVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDV 301 ++EL L RDGG PPR+S LRV++ DV Sbjct: 963 -------------------------------AHELELEARDGGSPPRTSHFRLRVVVQDV 991 Query: 302 NDN--SPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLR 359 +PRF Y DL + GT +LQ++A D G + A E Sbjct: 992 GTRGLAPRFNSPTYRVDLPSGTTAGTQVLQVQAQAPDGG-----PITYHLAAEGASSPFG 1046 Query: 360 LDETSGWLSVLHRIDREEVNQLRFTVMA-----RDRGQPPKTDKATVVLNIKDENDNVPS 414 L+ SGWL V +DRE VMA + GQ +T ATV ++I ++N++ P Sbjct: 1047 LEPQSGWLWVRAALDREAQELYILKVMAVSGSKAELGQ--QTGTATVRVSILNQNEHSP- 1103 Query: 415 IEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPAS 474 R+ VAE+ T + V +DRD G NG +T + L+ S Sbjct: 1104 -------RLSEDPTFLAVAENQPPGTSVGRVFATDRDSGPNGRLT--------YSLQQLS 1148 Query: 475 DTEGDQNKKKYFLHTST-------PLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGD 527 + + K + +H T LD E + +++ D GSP S+ ++ V V D Sbjct: 1149 E-----DSKAFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGGSPPRSTTGTVHVAVLD 1203 Query: 528 TNDNPPMFGQSV------VEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGI 581 NDN P F Q+ + + P+ PG V T+ A D D G+N I Y+L + Sbjct: 1204 LNDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLTGPGSEL 1263 Query: 582 FAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQV----------AD 631 F++ P SG++L L R + Y ++A D+G P S ++VQV D Sbjct: 1264 FSLHPHSGELLTAAPLIRAERPHYVLTLSAHDQGSPPRSASLQLLVQVLPSARLAEPPPD 1323 Query: 632 KNDNDPKF-MQDVFTFYVKENLQPNSPVGMVTVMD-ADKGRNAEMSLYIEENNNIFSIEN 689 + DP + V T E L+P S +G V + A G + + F+++ Sbjct: 1324 LAERDPAAPVPVVLTVTAAEGLRPGSLLGSVAAPEPAGVGALTYTLVGGADPEGTFALDA 1383 Query: 690 DTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNIS 749 +G +Y D E + +G + V + V DEN++AP ++ Sbjct: 1384 ASGRLYLARPLDFEAGPPWRALTVRAEGPGGAGARLLRVQVQVQDENEHAP--AFARDPL 1441 Query: 750 YTLLPPSSNVRTVVATVLATDSD-DGINADLNYSIVGGN-PFKLFEIDPTSGVVSLVGKL 807 LP + + T A+D+D G N+D+ Y ++ P +D +G +S L Sbjct: 1442 ALALPENPEPGAALYTFRASDADGPGPNSDVRYRLLRQEPPVPALRLDARTGALSAPRGL 1501 Query: 808 TQKHYGLHRLVVQVND---SGQPSQSTTTLVHVFVNESVSNATAIDS 851 ++ L+V+ D + ++ VFV + NA S Sbjct: 1502 DRETTPALLLLVEATDRPANASRRRAARVSARVFVTDENDNAPVFAS 1548 Score = 174 bits (442), Expect = 3e-43 Identities = 204/801 (25%), Positives = 317/801 (39%), Gaps = 123/801 (15%) Query: 52 ASDLGIVTGSGEVTFSLESGSE---YLKIDNLTGELSTSERRIDREKLPQCQMIFDENEC 108 A DL +G G++++SL + +D TG ++T+ +DRE + +++ Sbjct: 2195 ADDLDQGSG-GQISYSLAASQPARGLFHVDPTTGTITTTAI-LDREIWAETRLVL----- 2247 Query: 109 FLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTAT 168 ++ S + V V+V+D NDN PT P P L V E+ +G+ T Sbjct: 2248 -----MATDRGSPALVGSATLTVMVIDTNDNRPTIPQP-WELRVSEDALLGSEIAQVTGN 2301 Query: 169 DRDFGRNGIERYELLQEPGG------GGSGGESRRAGAAD--------------SAPYPG 208 D D +G + +L G G GG G D P+ G Sbjct: 2302 DVD---SGPVLWYVLSPSGPQDPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHDGPHEG 2358 Query: 209 GGG----------NGASGGGS------------GGSKRRLDASEGGGGTNPGGRSSVFEL 246 N + S G + + A++ G N G S Sbjct: 2359 RANLTVLVEDVNDNAPAFSQSLYQVMLLEHTPPGSAILSVSATDRDSGAN--GHISYHLA 2416 Query: 247 QVAD----TPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVN 302 AD P+ ++ AL + + ++ L RD G P R+++A + V + D N Sbjct: 2417 SPADGFSVDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDHGAPGRAARATVHVQLQDQN 2476 Query: 303 DNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVG-VNGQIEYV-----FGAATESVRR 356 D++P F S Y + E+ PG+ +L L A D D + ++Y +G + R Sbjct: 2477 DHAPSFTLSHYRVAVTEDLPPGSTLLTLEATDADGSRSHAAVDYSIISGNWGRVFQLEPR 2536 Query: 357 LLRLDETSG-------WLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDEN 409 L E++G L +L +D E + Q TV A DRGQPP++ V + + D N Sbjct: 2537 LAEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADRGQPPQSSVVPVTVTVLDVN 2596 Query: 410 DNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQ 469 DN P + R R+ V ED V + V+ SD D G +G+V TV P Sbjct: 2597 DN-PPVFTRASYRV-------TVPEDTPVGAELLHVEASDADPGPHGLVRFTVSSGDPSG 2648 Query: 470 LKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTN 529 L ++ G L + LD E +V+ A D + + ++V D N Sbjct: 2649 LFELDESSGT-------LRLAHALDCETQARHQLVVQAADPAGAHFALA-PVTIEVQDVN 2700 Query: 530 DNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMG-----IFAI 584 D+ P F +++ EN PG V T+ A D D+G + YSL + G FA+ Sbjct: 2701 DHGPAFPLNLLSTSVAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEGREAFAL 2760 Query: 585 DPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVF 644 + +G++ D E T+ + V A D G L S TV V V +++ DP F+ F Sbjct: 2761 NSSTGELRARVPFDYEHTESFRLLVGAADAGN--LSASVTVSVLVTGEDEYDPVFLAPAF 2818 Query: 645 TFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREH 704 F V E + +G V D D G + + + ++ F I TG +Y + Sbjct: 2819 HFQVPEGARRGHSLGHVQATDEDGGADGLVLYSLATSSPYFGINQTTGALYLRVDSRAPG 2878 Query: 705 QTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVA 764 T T + GG R A + L V+ P S TV Sbjct: 2879 SGTAT----SGGGGRTRREAPRELRLEVIARGPL----------------PGSRSATVPV 2918 Query: 765 TVLATDSDDGINADLNYSIVG 785 TV T + G+ DLN +VG Sbjct: 2919 TVDITHTALGLAPDLNLLLVG 2939 Score = 66.2 bits (160), Expect = 2e-10 Identities = 99/418 (23%), Positives = 158/418 (37%), Gaps = 95/418 (22%) Query: 35 RYRLAEEGPADVRIGNVASDLGIVTGSGEVTFSLESG--SEYLKIDNLTGELSTSERRID 92 R + E+ P + +V + G V F++ SG S ++D +G L + +D Sbjct: 2608 RVTVPEDTPVGAELLHVEASDADPGPHGLVRFTVSSGDPSGLFELDESSGTLRLAHA-LD 2666 Query: 93 REKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTLTV 152 E + Q++ V P+ + L + V D+ND+ P FP +L+ +V Sbjct: 2667 CETQARHQLV-----------VQAADPAGAHFALAPVTIEVQDVNDHGPAFPLNLLSTSV 2715 Query: 153 EENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGGGGN 212 EN+P GTL A D D G G RY LL+ G G E R A A Sbjct: 2716 AENQPPGTLVTTLHAIDGDAGAFGRLRYSLLE----AGPGPEGREAFA------------ 2759 Query: 213 GASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQRD 272 L++S G +L + D E + Sbjct: 2760 -------------LNSSTG---------------------------ELRARVPFDYEHTE 2779 Query: 273 SYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRA 332 S+ L + D G+ S+ + VL+T ++ P F + + E + G + ++A Sbjct: 2780 SFRLLVGAADAGN--LSASVTVSVLVTGEDEYDPVFLAPAFHFQVPEGARRGHSLGHVQA 2837 Query: 333 ADLDVGVNGQIEY-------VFGAATESVRRLLRLDE--------TSGWLSVLHRIDREE 377 D D G +G + Y FG + LR+D TSG R RE Sbjct: 2838 TDEDGGADGLVLYSLATSSPYFGINQTTGALYLRVDSRAPGSGTATSGGGG---RTRREA 2894 Query: 378 VNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNV---PSIEIRKIGRIPLKDGVANV 432 +LR V+A RG P + ATV + + + + P + + +G + GV V Sbjct: 2895 PRELRLEVIA--RGPLPGSRSATVPVTVDITHTALGLAPDLNLLLVGAVAASLGVVVV 2950 Score = 31.2 bits (69), Expect = 5.5 Identities = 55/228 (24%), Positives = 83/228 (36%), Gaps = 29/228 (12%) Query: 33 LLRYRLAEEGPADVRIGNVASDLGIVTGSGEVTFSL------ESGSEYLKIDNLTGELST 86 LL +AE P + + + G G + +SL G E +++ TGEL Sbjct: 2710 LLSTSVAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEGREAFALNSSTGEL-- 2767 Query: 87 SERRIDREKLPQCQMIFDENECF-LDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPS 145 R ++P ++ E F L + G + V + V+V ++ P F + Sbjct: 2768 ------RARVP---FDYEHTESFRLLVGAADAGNLSASVTV---SVLVTGEDEYDPVFLA 2815 Query: 146 PVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAP 205 P V E G ATD D G +G+ Y L G ++ GA Sbjct: 2816 PAFHFQVPEGARRGHSLGHVQATDEDGGADGLVLYSLAT---SSPYFGINQTTGALYLRV 2872 Query: 206 YPGGGGNGASGGGSGGSKRR-----LDASEGGGGTNPGGRSSVFELQV 248 G+G + G GG RR L G PG RS+ + V Sbjct: 2873 DSRAPGSGTATSGGGGRTRREAPRELRLEVIARGPLPGSRSATVPVTV 2920 >gi|14270505 protocadherin gamma subfamily B, 5 isoform 2 precursor [Homo sapiens] Length = 818 Score = 317 bits (813), Expect = 3e-86 Identities = 229/731 (31%), Positives = 335/731 (45%), Gaps = 103/731 (14%) Query: 20 LLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYLKID 78 L LSL A + +RYR+ EE P +GN+A+DLG V + S Y + Sbjct: 19 LFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVS 78 Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDIND 138 +GEL S R +DRE++ + C L+FE P ++ + V + DIND Sbjct: 79 AESGELLVSSR-LDREEI-----CGKKPACALEFEAVAENP----LNFYHVNVEIEDIND 128 Query: 139 NTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRA 198 +TP F L + E+ GT ++L A D D G N +++Y+L P E + Sbjct: 129 HTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQ-- 186 Query: 199 GAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQP 258 D + YP EL + T D Sbjct: 187 ---DGSKYP-------------------------------------ELALEKTLD----- 201 Query: 259 QLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLA 318 REQ+ + L L DGG PP S LR+ +TD NDN P F + VY L Sbjct: 202 ---------REQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLR 252 Query: 319 ENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEV 378 EN PGT +LQ+ A D D G+N +I Y F ++ L+ SG ++ ++D EE Sbjct: 253 ENVPPGTTVLQVSATDQDEGINSEITYSF----YRTGQIFSLNSKSGEITTQKKLDFEET 308 Query: 379 NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLV 438 + V RD G + TV +NI+DENDN P + + + + E+ + Sbjct: 309 KEYSMVVEGRDGG--GLVAQCTVEINIQDENDNSPEVTFHSL--------LEMILENAVP 358 Query: 439 DTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEAT 498 T IAL+++ D+D GENG V C + G+VPF++ +S K Y L T LD E T Sbjct: 359 GTLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSS-------KNSYKLVTDGTLDREQT 411 Query: 499 REFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVL 558 E+NV I A D G P LSS+ S+I+ + D NDN P+F Q+ V PENN PG +A V Sbjct: 412 PEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIAQVC 471 Query: 559 ATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAK 612 A+D D G N +++YS+ +S + ++ SG + D EQ +E + A+ Sbjct: 472 ASDLDLGLNGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDYEQLRTFELTLQAR 531 Query: 613 DKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNSPVGMVTVMD 665 D+G P L + ++ V V D+NDN P+ + V +P V V +D Sbjct: 532 DQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVD 591 Query: 666 ADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRS 723 AD G NA +S ++ + + +FS+ TG + + + V DGG PP S Sbjct: 592 ADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLS 651 Query: 724 ATATVSLFVMD 734 ATAT+ L D Sbjct: 652 ATATLHLVFAD 662 Score = 237 bits (604), Expect = 5e-62 Identities = 183/670 (27%), Positives = 314/670 (46%), Gaps = 56/670 (8%) Query: 259 QLIVKGALDREQRDSYE--LTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEAD 316 +L+V LDRE+ + L + P + + V I D+ND++P+F ++ +E Sbjct: 83 ELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHV-NVEIEDINDHTPKFTQNSFELQ 141 Query: 317 LAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW--LSVLHRID 374 ++E++ PGT + A D D+G+N +Y + + S + L++ +D Sbjct: 142 ISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALEKTLD 201 Query: 375 REEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAE 434 RE+ + R + A D G PP + + + + D NDN P R + R+ L+ E Sbjct: 202 REQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFN-RDVYRVSLR-------E 253 Query: 435 DVLVDTPIALVQVSDRDQGENGVVTCTV--VGDVPFQLKPASDTEGDQNKKKYFLHTSTP 492 +V T + V +D+D+G N +T + G + F L N K + T Sbjct: 254 NVPPGTTVLQVSATDQDEGINSEITYSFYRTGQI-FSL----------NSKSGEITTQKK 302 Query: 493 LDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPP-MFGQSVVEVYFPENNIPG 551 LD+E T+E+++V+ D G L + ++ + + D NDN P + S++E+ EN +PG Sbjct: 303 LDFEETKEYSMVVEGRDGGG--LVAQCTVEINIQDENDNSPEVTFHSLLEMIL-ENAVPG 359 Query: 552 ERVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFKVN 610 +A + D DSG+N E+ L V I + +S ++ + LDREQT Y + Sbjct: 360 TLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTIT 419 Query: 611 AKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGR 670 A D+G P L S +VI+ + D NDN P F Q + V EN P + + V D D G Sbjct: 420 ATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIAQVCASDLDLGL 479 Query: 671 NAEMSLYIEENN-------NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRS 723 N ++S I ++ + S+ +G +++ +FD E T+ ++A D G P S Sbjct: 480 NGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDYEQLRTFELTLQARDQGSPALS 539 Query: 724 ATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGINAD 778 A ++ + V D NDNAP V P + + ++P ++ +V V+A D+D G NA Sbjct: 540 ANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAW 599 Query: 779 LNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVF 838 L+Y ++ + LF + +G V L + RL+V V D GQP S T +H+ Sbjct: 600 LSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLV 659 Query: 839 VNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIV 898 +S+ L + + DP E+ + +V+ + + +L +++ Sbjct: 660 FADSLQEV----------LPDITDRPVPSDPQAEL---QFYLVVALALISVLFLLAVILA 706 Query: 899 VMARYCRSKN 908 V R RS + Sbjct: 707 VALRLRRSSS 716 Score = 101 bits (252), Expect = 3e-21 Identities = 80/269 (29%), Positives = 130/269 (48%), Gaps = 35/269 (13%) Query: 576 SSVMGIFAIDPDSGDILVNTVLDREQ------TDRYEFKVNAKDKGIPVLQGSTTVIVQV 629 SS F + +SG++LV++ LDRE+ EF+ A++ V V++ Sbjct: 69 SSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENP-----LNFYHVNVEI 123 Query: 630 ADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNA--EMSLYIEENNNIFSI 687 D ND+ PKF Q+ F + E+ QP + + DAD G N+ + L + + ++ Sbjct: 124 EDINDHTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIK 183 Query: 688 ENDTGTIYSTM----SFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-- 741 E G+ Y + + DRE Q+ + + A+DGG PP S T + + V D NDN P Sbjct: 184 EKQDGSKYPELALEKTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFN 243 Query: 742 -----VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDP 796 V+L +N+ PP T V V ATD D+GIN+++ YS ++F ++ Sbjct: 244 RDVYRVSLRENV-----PPG----TTVLQVSATDQDEGINSEITYSFY--RTGQIFSLNS 292 Query: 797 TSGVVSLVGKLTQKHYGLHRLVVQVNDSG 825 SG ++ KL + + +VV+ D G Sbjct: 293 KSGEITTQKKLDFEETKEYSMVVEGRDGG 321 >gi|11128031 protocadherin gamma subfamily B, 5 isoform 1 precursor [Homo sapiens] Length = 923 Score = 317 bits (813), Expect = 3e-86 Identities = 229/731 (31%), Positives = 335/731 (45%), Gaps = 103/731 (14%) Query: 20 LLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYLKID 78 L LSL A + +RYR+ EE P +GN+A+DLG V + S Y + Sbjct: 19 LFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVS 78 Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDIND 138 +GEL S R +DRE++ + C L+FE P ++ + V + DIND Sbjct: 79 AESGELLVSSR-LDREEI-----CGKKPACALEFEAVAENP----LNFYHVNVEIEDIND 128 Query: 139 NTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRA 198 +TP F L + E+ GT ++L A D D G N +++Y+L P E + Sbjct: 129 HTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQ-- 186 Query: 199 GAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQP 258 D + YP EL + T D Sbjct: 187 ---DGSKYP-------------------------------------ELALEKTLD----- 201 Query: 259 QLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLA 318 REQ+ + L L DGG PP S LR+ +TD NDN P F + VY L Sbjct: 202 ---------REQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLR 252 Query: 319 ENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEV 378 EN PGT +LQ+ A D D G+N +I Y F ++ L+ SG ++ ++D EE Sbjct: 253 ENVPPGTTVLQVSATDQDEGINSEITYSF----YRTGQIFSLNSKSGEITTQKKLDFEET 308 Query: 379 NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLV 438 + V RD G + TV +NI+DENDN P + + + + E+ + Sbjct: 309 KEYSMVVEGRDGG--GLVAQCTVEINIQDENDNSPEVTFHSL--------LEMILENAVP 358 Query: 439 DTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEAT 498 T IAL+++ D+D GENG V C + G+VPF++ +S K Y L T LD E T Sbjct: 359 GTLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSS-------KNSYKLVTDGTLDREQT 411 Query: 499 REFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVL 558 E+NV I A D G P LSS+ S+I+ + D NDN P+F Q+ V PENN PG +A V Sbjct: 412 PEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIAQVC 471 Query: 559 ATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAK 612 A+D D G N +++YS+ +S + ++ SG + D EQ +E + A+ Sbjct: 472 ASDLDLGLNGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDYEQLRTFELTLQAR 531 Query: 613 DKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNSPVGMVTVMD 665 D+G P L + ++ V V D+NDN P+ + V +P V V +D Sbjct: 532 DQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVD 591 Query: 666 ADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRS 723 AD G NA +S ++ + + +FS+ TG + + + V DGG PP S Sbjct: 592 ADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLS 651 Query: 724 ATATVSLFVMD 734 ATAT+ L D Sbjct: 652 ATATLHLVFAD 662 Score = 237 bits (604), Expect = 5e-62 Identities = 183/670 (27%), Positives = 314/670 (46%), Gaps = 56/670 (8%) Query: 259 QLIVKGALDREQRDSYE--LTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEAD 316 +L+V LDRE+ + L + P + + V I D+ND++P+F ++ +E Sbjct: 83 ELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHV-NVEIEDINDHTPKFTQNSFELQ 141 Query: 317 LAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW--LSVLHRID 374 ++E++ PGT + A D D+G+N +Y + + S + L++ +D Sbjct: 142 ISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALEKTLD 201 Query: 375 REEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAE 434 RE+ + R + A D G PP + + + + D NDN P R + R+ L+ E Sbjct: 202 REQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFN-RDVYRVSLR-------E 253 Query: 435 DVLVDTPIALVQVSDRDQGENGVVTCTV--VGDVPFQLKPASDTEGDQNKKKYFLHTSTP 492 +V T + V +D+D+G N +T + G + F L N K + T Sbjct: 254 NVPPGTTVLQVSATDQDEGINSEITYSFYRTGQI-FSL----------NSKSGEITTQKK 302 Query: 493 LDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPP-MFGQSVVEVYFPENNIPG 551 LD+E T+E+++V+ D G L + ++ + + D NDN P + S++E+ EN +PG Sbjct: 303 LDFEETKEYSMVVEGRDGGG--LVAQCTVEINIQDENDNSPEVTFHSLLEMIL-ENAVPG 359 Query: 552 ERVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFKVN 610 +A + D DSG+N E+ L V I + +S ++ + LDREQT Y + Sbjct: 360 TLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTIT 419 Query: 611 AKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGR 670 A D+G P L S +VI+ + D NDN P F Q + V EN P + + V D D G Sbjct: 420 ATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIAQVCASDLDLGL 479 Query: 671 NAEMSLYIEENN-------NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRS 723 N ++S I ++ + S+ +G +++ +FD E T+ ++A D G P S Sbjct: 480 NGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDYEQLRTFELTLQARDQGSPALS 539 Query: 724 ATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGINAD 778 A ++ + V D NDNAP V P + + ++P ++ +V V+A D+D G NA Sbjct: 540 ANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAW 599 Query: 779 LNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVF 838 L+Y ++ + LF + +G V L + RL+V V D GQP S T +H+ Sbjct: 600 LSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLV 659 Query: 839 VNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIV 898 +S+ L + + DP E+ + +V+ + + +L +++ Sbjct: 660 FADSLQEV----------LPDITDRPVPSDPQAEL---QFYLVVALALISVLFLLAVILA 706 Query: 899 VMARYCRSKN 908 V R RS + Sbjct: 707 VALRLRRSSS 716 Score = 101 bits (252), Expect = 3e-21 Identities = 80/269 (29%), Positives = 130/269 (48%), Gaps = 35/269 (13%) Query: 576 SSVMGIFAIDPDSGDILVNTVLDREQ------TDRYEFKVNAKDKGIPVLQGSTTVIVQV 629 SS F + +SG++LV++ LDRE+ EF+ A++ V V++ Sbjct: 69 SSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENP-----LNFYHVNVEI 123 Query: 630 ADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNA--EMSLYIEENNNIFSI 687 D ND+ PKF Q+ F + E+ QP + + DAD G N+ + L + + ++ Sbjct: 124 EDINDHTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIK 183 Query: 688 ENDTGTIYSTM----SFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-- 741 E G+ Y + + DRE Q+ + + A+DGG PP S T + + V D NDN P Sbjct: 184 EKQDGSKYPELALEKTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFN 243 Query: 742 -----VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDP 796 V+L +N+ PP T V V ATD D+GIN+++ YS ++F ++ Sbjct: 244 RDVYRVSLRENV-----PPG----TTVLQVSATDQDEGINSEITYSFY--RTGQIFSLNS 292 Query: 797 TSGVVSLVGKLTQKHYGLHRLVVQVNDSG 825 SG ++ KL + + +VV+ D G Sbjct: 293 KSGEITTQKKLDFEETKEYSMVVEGRDGG 321 >gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] Length = 950 Score = 315 bits (808), Expect = 1e-85 Identities = 243/748 (32%), Positives = 349/748 (46%), Gaps = 109/748 (14%) Query: 18 CLLLPLSLSLAAAKQL----LRYRLAEEGPADVRIGNVASDLGIVTGS---GEVTFSLES 70 CLLL SL L AA ++ L Y ++EE +G +A DLG+ + + Sbjct: 13 CLLL--SLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKR 70 Query: 71 GSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQ 130 + L+++ G L + R IDRE+L C EC + EV V P Q +F + Sbjct: 71 HGDLLEVNLQNGILFVNSR-IDREEL--CGR---SAECSIHLEVIVDRPLQ----VFHVE 120 Query: 131 VIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGG 190 V V DINDN P FP V L + E+R G+ + L A+D D G N + Y L Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSL-------- 172 Query: 191 SGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVAD 250 DS Y F L V Sbjct: 173 -----------DSTEY-------------------------------------FTLDVKR 184 Query: 251 TPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEK 310 + K L++K L+RE + L + DGG P + L++ + DVNDN+P FE+ Sbjct: 185 NDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFER 244 Query: 311 SVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGA-ATESVRRLLRLDETSGWLSV 369 ++Y+ L EN+ GT ++ + A DLD GVN I Y F + + LD +G +SV Sbjct: 245 TIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISV 304 Query: 370 LHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGV 429 ID EE V A D+G PP +D TV+L I D NDNVP + I+ + +P Sbjct: 305 KGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLS-LP----- 358 Query: 430 ANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHT 489 V ED + T IAL+ VSDRD G NG VTC++ VPF+L K Y L Sbjct: 359 --VLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTF-------KNYYSLVL 409 Query: 490 STPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNI 549 +PLD E+ + +V+ A D GSPSL + S+ V+V D NDN P F QS V+ ENN Sbjct: 410 DSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNP 469 Query: 550 PGERVATVLATDADSGKNAEIAYSL------DSSVMGIFAIDPDSGDILVNTVLDREQTD 603 PG + TV A DAD+ +NA ++YSL + ++ ++ +SG + LD E+ + Sbjct: 470 PGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELE 529 Query: 604 RYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNS 656 +F+V+A+D G+P L + T+ V V D+NDN P + + V ++ Sbjct: 530 LLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGH 589 Query: 657 PVGMVTVMDADKGRNAEMSLYIEENNN----IFSIENDTGTIYSTMSFDREHQTTYTFRV 712 V V +DAD G NA +S ++ F + TG I +T + D + V Sbjct: 590 VVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLV 649 Query: 713 KAVDGGDPPRSATATVSLFVMDENDNAP 740 D G+P +ATATV L + E+ AP Sbjct: 650 LVKDHGEPSLTATATV-LVSLVESGQAP 676 Score = 233 bits (593), Expect = 9e-61 Identities = 184/678 (27%), Positives = 313/678 (46%), Gaps = 57/678 (8%) Query: 260 LIVKGALDREQR--DSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317 L V +DRE+ S E ++ + D P + V + D+NDN+P F +V + Sbjct: 84 LFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV-EVEVKDINDNAPVFPMAVKNLFI 142 Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHR--IDR 375 +E+ PG+ A+D D+G N + Y + + R DE L ++ + ++R Sbjct: 143 SESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGLVLKKNLNR 202 Query: 376 EEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAED 435 E+ + + A D G+P T + + + D NDN P+ E R I ++ L + N Sbjct: 203 EDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFE-RTIYKVRLLENAPN---- 257 Query: 436 VLVDTPIALVQVSDRDQGENGVVTCTVVGDVP------FQLKPASDTEGDQNKKKYFLHT 489 T + V +D D+G N + + D+ F L P + + Sbjct: 258 ---GTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQ----------ISV 304 Query: 490 STPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNI 549 +D+E ++ + + + A D G+P +S + ++++++ D NDN P + + E++ Sbjct: 305 KGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSP 364 Query: 550 PGERVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFK 608 +A + +D DSG N ++ SL V + + + +++++ LDRE YE Sbjct: 365 LSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELV 424 Query: 609 VNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADK 668 V A+D G P L + +V V+VAD NDN P F Q +T +VKEN P + V+ DAD Sbjct: 425 VTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADA 484 Query: 669 GRNAEMSLYIEEN-------NNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPP 721 NA +S + E ++ S+ ++G +Y+ D E F+V A D G PP Sbjct: 485 QENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPP 544 Query: 722 RSATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGIN 776 + T+ +FV+DENDNAP + +P+ L+P S VVA V A D+D G N Sbjct: 545 LGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYN 604 Query: 777 ADLNYSI---VGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTT 833 A L+Y + GG F + +G +S L + HRL+V V D G+PS + T Sbjct: 605 AWLSYELQPGTGGARIP-FRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATA 663 Query: 834 LVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVIL 893 V V + ES A SQ + A P + + +++ + A + ++++ Sbjct: 664 TVLVSLVES-GQAPKASSQASAG---------ATGPEAALVDVNVYLIVAICA-VSSLLV 712 Query: 894 IILIVVMARYCRSKNKNG 911 + L++ A C + G Sbjct: 713 LTLLLYTALRCSAPPTEG 730 Score = 182 bits (463), Expect = 1e-45 Identities = 161/552 (29%), Positives = 257/552 (46%), Gaps = 40/552 (7%) Query: 317 LAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDRE 376 ++E + GT + ++ A DL + + + +F A++ LL ++ +G L V RIDRE Sbjct: 35 VSEEAKHGTFVGRI-AQDLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDRE 93 Query: 377 EV------NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 430 E+ + V+ DR V + +KD NDN P P+ Sbjct: 94 ELCGRSAECSIHLEVIV-DR----PLQVFHVEVEVKDINDNAPV--------FPMAVKNL 140 Query: 431 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 490 ++E + +L SD D G N ++T ++ F L D+ K L Sbjct: 141 FISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL---DVKRNDEEIKSLGLVLK 197 Query: 491 TPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIP 550 L+ E T + ++I A+D G P L+ L + V D NDN P F +++ +V EN Sbjct: 198 KNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPN 257 Query: 551 GERVATVLATDADSGKNAEIAYS----LDSSVMGIFAIDPDSGDILVNTVLDREQTDRYE 606 G V TV ATD D G N +IAYS + + ++ F +DP +G I V +D E++ YE Sbjct: 258 GTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYE 317 Query: 607 FKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDA 666 +V A DKG P + TV++++ D NDN P+ + + V E+ ++ + +++V D Sbjct: 318 IQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISVSDR 377 Query: 667 DKGRNAEMSLYIEENNNIFSIENDTGTIYSTM---SFDREHQTTYTFRVKAVDGGDPPRS 723 D G N +++ + + F + + YS + DRE + Y V A DGG P Sbjct: 378 DSGVNGQVTCSLTPHVP-FKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLW 436 Query: 724 ATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTV-VATVLATDSDDGINADLNYS 782 ATA+VS+ V D NDNAP + YT+ +N + TV A D+D NA ++YS Sbjct: 437 ATASVSVEVADVNDNAPAFS---QSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493 Query: 783 I----VGGNPFKLF-EIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837 + VG + + SG V + L + L + V D+G P + + V Sbjct: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553 Query: 838 FVNESVSNATAI 849 FV + NA A+ Sbjct: 554 FVLDENDNAPAL 565 >gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapiens] Length = 824 Score = 315 bits (808), Expect = 1e-85 Identities = 243/748 (32%), Positives = 349/748 (46%), Gaps = 109/748 (14%) Query: 18 CLLLPLSLSLAAAKQL----LRYRLAEEGPADVRIGNVASDLGIVTGS---GEVTFSLES 70 CLLL SL L AA ++ L Y ++EE +G +A DLG+ + + Sbjct: 13 CLLL--SLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKR 70 Query: 71 GSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQ 130 + L+++ G L + R IDRE+L C EC + EV V P Q +F + Sbjct: 71 HGDLLEVNLQNGILFVNSR-IDREEL--CGR---SAECSIHLEVIVDRPLQ----VFHVE 120 Query: 131 VIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGG 190 V V DINDN P FP V L + E+R G+ + L A+D D G N + Y L Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSL-------- 172 Query: 191 SGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVAD 250 DS Y F L V Sbjct: 173 -----------DSTEY-------------------------------------FTLDVKR 184 Query: 251 TPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEK 310 + K L++K L+RE + L + DGG P + L++ + DVNDN+P FE+ Sbjct: 185 NDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFER 244 Query: 311 SVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGA-ATESVRRLLRLDETSGWLSV 369 ++Y+ L EN+ GT ++ + A DLD GVN I Y F + + LD +G +SV Sbjct: 245 TIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISV 304 Query: 370 LHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGV 429 ID EE V A D+G PP +D TV+L I D NDNVP + I+ + +P Sbjct: 305 KGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLS-LP----- 358 Query: 430 ANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHT 489 V ED + T IAL+ VSDRD G NG VTC++ VPF+L K Y L Sbjct: 359 --VLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTF-------KNYYSLVL 409 Query: 490 STPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNI 549 +PLD E+ + +V+ A D GSPSL + S+ V+V D NDN P F QS V+ ENN Sbjct: 410 DSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNP 469 Query: 550 PGERVATVLATDADSGKNAEIAYSL------DSSVMGIFAIDPDSGDILVNTVLDREQTD 603 PG + TV A DAD+ +NA ++YSL + ++ ++ +SG + LD E+ + Sbjct: 470 PGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELE 529 Query: 604 RYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENLQPNS 656 +F+V+A+D G+P L + T+ V V D+NDN P + + V ++ Sbjct: 530 LLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGH 589 Query: 657 PVGMVTVMDADKGRNAEMSLYIEENNN----IFSIENDTGTIYSTMSFDREHQTTYTFRV 712 V V +DAD G NA +S ++ F + TG I +T + D + V Sbjct: 590 VVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLV 649 Query: 713 KAVDGGDPPRSATATVSLFVMDENDNAP 740 D G+P +ATATV L + E+ AP Sbjct: 650 LVKDHGEPSLTATATV-LVSLVESGQAP 676 Score = 233 bits (593), Expect = 9e-61 Identities = 184/678 (27%), Positives = 313/678 (46%), Gaps = 57/678 (8%) Query: 260 LIVKGALDREQR--DSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317 L V +DRE+ S E ++ + D P + V + D+NDN+P F +V + Sbjct: 84 LFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV-EVEVKDINDNAPVFPMAVKNLFI 142 Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHR--IDR 375 +E+ PG+ A+D D+G N + Y + + R DE L ++ + ++R Sbjct: 143 SESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGLVLKKNLNR 202 Query: 376 EEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAED 435 E+ + + A D G+P T + + + D NDN P+ E R I ++ L + N Sbjct: 203 EDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFE-RTIYKVRLLENAPN---- 257 Query: 436 VLVDTPIALVQVSDRDQGENGVVTCTVVGDVP------FQLKPASDTEGDQNKKKYFLHT 489 T + V +D D+G N + + D+ F L P + + Sbjct: 258 ---GTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQ----------ISV 304 Query: 490 STPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNI 549 +D+E ++ + + + A D G+P +S + ++++++ D NDN P + + E++ Sbjct: 305 KGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSP 364 Query: 550 PGERVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFK 608 +A + +D DSG N ++ SL V + + + +++++ LDRE YE Sbjct: 365 LSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELV 424 Query: 609 VNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADK 668 V A+D G P L + +V V+VAD NDN P F Q +T +VKEN P + V+ DAD Sbjct: 425 VTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADA 484 Query: 669 GRNAEMSLYIEEN-------NNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPP 721 NA +S + E ++ S+ ++G +Y+ D E F+V A D G PP Sbjct: 485 QENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPP 544 Query: 722 RSATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGIN 776 + T+ +FV+DENDNAP + +P+ L+P S VVA V A D+D G N Sbjct: 545 LGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYN 604 Query: 777 ADLNYSI---VGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTT 833 A L+Y + GG F + +G +S L + HRL+V V D G+PS + T Sbjct: 605 AWLSYELQPGTGGARIP-FRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATA 663 Query: 834 LVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVIL 893 V V + ES A SQ + A P + + +++ + A + ++++ Sbjct: 664 TVLVSLVES-GQAPKASSQASAG---------ATGPEAALVDVNVYLIVAICA-VSSLLV 712 Query: 894 IILIVVMARYCRSKNKNG 911 + L++ A C + G Sbjct: 713 LTLLLYTALRCSAPPTEG 730 Score = 182 bits (463), Expect = 1e-45 Identities = 161/552 (29%), Positives = 257/552 (46%), Gaps = 40/552 (7%) Query: 317 LAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDRE 376 ++E + GT + ++ A DL + + + +F A++ LL ++ +G L V RIDRE Sbjct: 35 VSEEAKHGTFVGRI-AQDLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDRE 93 Query: 377 EV------NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 430 E+ + V+ DR V + +KD NDN P P+ Sbjct: 94 ELCGRSAECSIHLEVIV-DR----PLQVFHVEVEVKDINDNAPV--------FPMAVKNL 140 Query: 431 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 490 ++E + +L SD D G N ++T ++ F L D+ K L Sbjct: 141 FISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL---DVKRNDEEIKSLGLVLK 197 Query: 491 TPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIP 550 L+ E T + ++I A+D G P L+ L + V D NDN P F +++ +V EN Sbjct: 198 KNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPN 257 Query: 551 GERVATVLATDADSGKNAEIAYS----LDSSVMGIFAIDPDSGDILVNTVLDREQTDRYE 606 G V TV ATD D G N +IAYS + + ++ F +DP +G I V +D E++ YE Sbjct: 258 GTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYE 317 Query: 607 FKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDA 666 +V A DKG P + TV++++ D NDN P+ + + V E+ ++ + +++V D Sbjct: 318 IQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISVSDR 377 Query: 667 DKGRNAEMSLYIEENNNIFSIENDTGTIYSTM---SFDREHQTTYTFRVKAVDGGDPPRS 723 D G N +++ + + F + + YS + DRE + Y V A DGG P Sbjct: 378 DSGVNGQVTCSLTPHVP-FKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLW 436 Query: 724 ATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTV-VATVLATDSDDGINADLNYS 782 ATA+VS+ V D NDNAP + YT+ +N + TV A D+D NA ++YS Sbjct: 437 ATASVSVEVADVNDNAPAFS---QSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493 Query: 783 I----VGGNPFKLF-EIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 837 + VG + + SG V + L + L + V D+G P + + V Sbjct: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553 Query: 838 FVNESVSNATAI 849 FV + NA A+ Sbjct: 554 FVLDENDNAPAL 565 >gi|11036656 protocadherin beta 7 precursor [Homo sapiens] Length = 793 Score = 312 bits (800), Expect = 9e-85 Identities = 233/769 (30%), Positives = 358/769 (46%), Gaps = 124/769 (16%) Query: 23 LSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSGEVT-----FSLESGSEYLKI 77 L +S A A+ L RY +AEE + N+A DLG+ G GE+ + + L + Sbjct: 21 LGMSWAGAEPL-RYFVAEETERGTFLTNLAKDLGL--GVGELRARGTRIVSDQNMQILLL 77 Query: 78 DNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDIN 137 +LTG+L +E+ +DRE+L C L F++ + P Q +F ++ V DIN Sbjct: 78 SSLTGDLLLNEK-LDREEL-----CGPREPCVLPFQLLLEKPFQ----IFRAELWVRDIN 127 Query: 138 DNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRR 197 D+ P F ++L + E+ G +LL +A D D G N + Y + Sbjct: 128 DHAPVFLDREISLKILESTTPGAAFLLESAQDSDVGTNSLSNYTI--------------- 172 Query: 198 AGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQ 257 S + ++ + G G + EL + D E+ Sbjct: 173 ---------------------SPNAYFHINVHDSGEG------NIYPELVLNQVLDREEI 205 Query: 258 PQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317 P+ + LTL DGG PPRS A++R+L+ DVNDN+P F +S+Y+ + Sbjct: 206 PE--------------FSLTLTALDGGSPPRSGTALVRILVLDVNDNAPDFVRSLYKVQV 251 Query: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREE 377 ENS G+ ++ + A DLD G NG+I Y F ATE + + +++ TSG L + ++D E Sbjct: 252 PENSPVGSMVVSVSARDLDTGSNGEIAYAFSYATERILKTFQINPTSGSLHLKAQLDYEA 311 Query: 378 VNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVL 437 + T+ A+D G + K TVV+++ D NDN P + + + + +AE+ Sbjct: 312 IQTYTLTIQAKDGG--GLSGKCTVVVDVTDINDNRPELLLSSL--------TSPIAEN-S 360 Query: 438 VDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEA 497 +T +A+ ++ DRD G NG C++ DVPF LKP+ + Y L T PLD E Sbjct: 361 PETVVAVFRIRDRDSGNNGKTVCSIQDDVPFILKPSVE-------NFYTLVTEKPLDRER 413 Query: 498 TREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATV 557 E+N+ I D G+P L + +++ V V D NDN P F Q+ ++ ENN P + +V Sbjct: 414 NTEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALPIGSV 473 Query: 558 LATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNA 611 ATD DSG NA++ YSL S + + +I+ D+G + LD E +EF+V A Sbjct: 474 SATDRDSGTNAQVIYSLLPSQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGA 533 Query: 612 KDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKEN------------LQPNSPVG 659 D+G P L V V V D NDN P F Y +N +P V Sbjct: 534 TDRGSPALSSEALVRVLVLDANDNSP------FVLYPLQNSSAPCTEPLPRAAEPGYLVT 587 Query: 660 MVTVMDADKGRNAEMS--LYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDG 717 V +D D G+NA +S L +F + G + + V D Sbjct: 588 KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKQRLVVLVKDN 647 Query: 718 GDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATV 766 G+PPRSATAT+ + ++D + P + LP+ P +N TV V Sbjct: 648 GEPPRSATATLHVLLVD-GFSQPYLRLPE-----AAPDQANSLTVYLVV 690 Score = 229 bits (584), Expect = 1e-59 Identities = 185/629 (29%), Positives = 283/629 (44%), Gaps = 59/629 (9%) Query: 298 ITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRL 357 + D+ND++P F + E++ PG L A D DVG N Y + + + Sbjct: 123 VRDINDHAPVFLDREISLKILESTTPGAAFLLESAQDSDVGTNSLSNYTI--SPNAYFHI 180 Query: 358 LRLDETSGWLS---VLHRI-DREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVP 413 D G + VL+++ DREE+ + T+ A D G PP++ A V + + D NDN P Sbjct: 181 NVHDSGEGNIYPELVLNQVLDREEIPEFSLTLTALDGGSPPRSGTALVRILVLDVNDNAP 240 Query: 414 SIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVP-----F 468 +R + ++ V E+ V + + V D D G NG + F Sbjct: 241 DF-VRSLYKV-------QVPENSPVGSMVVSVSARDLDTGSNGEIAYAFSYATERILKTF 292 Query: 469 QLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDT 528 Q+ P S + LH LDYEA + + + I A D G LS +++V V D Sbjct: 293 QINPTSGS----------LHLKAQLDYEAIQTYTLTIQAKDGGG--LSGKCTVVVDVTDI 340 Query: 529 NDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDS 588 NDN P S + EN+ P VA D DSG N + S+ V I ++ Sbjct: 341 NDNRPELLLSSLTSPIAENS-PETVVAVFRIRDRDSGNNGKTVCSIQDDVPFILKPSVEN 399 Query: 589 GDILVNTV-LDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFY 647 LV LDRE+ Y + D G P L+ + V V+D NDN P F Q +T + Sbjct: 400 FYTLVTEKPLDRERNTEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLF 459 Query: 648 VKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNN-------IFSIENDTGTIYSTMSF 700 V+EN P P+G V+ D D G NA++ + + + + SI D G +++ S Sbjct: 460 VRENNSPALPIGSVSATDRDSGTNAQVIYSLLPSQDPHLPLASLVSINADNGHLFALRSL 519 Query: 701 DREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTL----LPPS 756 D E + FRV A D G P S+ A V + V+D NDN+P V P S LP + Sbjct: 520 DYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNSSAPCTEPLPRA 579 Query: 757 SNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHR 816 + +V V+A D D G NA L+Y ++ LF + +G V L+++ R Sbjct: 580 AEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKQR 639 Query: 817 LVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQ 876 LVV V D+G+P +S T +HV + +D L +P + A D + ++ Sbjct: 640 LVVLVKDNGEPPRSATATLHVLL---------VDGFSQPYLRLP---EAAPDQANSLT-- 685 Query: 877 RLSIVIGVVAGIMTVILIILIVVMARYCR 905 + +V+ + + +L +L+ V R CR Sbjct: 686 -VYLVVALASVSSLFLLSVLLFVAVRLCR 713 >gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] Length = 1040 Score = 312 bits (799), Expect = 1e-84 Identities = 237/758 (31%), Positives = 344/758 (45%), Gaps = 124/758 (16%) Query: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI----VTGSGEVTFSLESGSEY 74 LL L + L Y + EE +GN+A DLG+ ++ G T S + Y Sbjct: 5 LLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVP-NSRTPY 63 Query: 75 LKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVL 134 L ++ TG L +E+ IDRE++ C+ C L EV + P ++LF+ ++ VL Sbjct: 64 LDLNLETGVLYVNEK-IDREQI--CKQ---SPSCVLHLEVFLENP----LELFQVEIEVL 113 Query: 135 DINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYEL---------LQE 185 DINDN P+FP P LT+ + E+ GT + L +A D D G N + YE+ +Q Sbjct: 114 DINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQT 173 Query: 186 PGGGGSGGESRRAGAADS----------APYPGGGGNGASGGGSGGSKRRLDASEGGGGT 235 G G E D GGGG G GG GG GG G Sbjct: 174 QGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGG---------GGAGL 224 Query: 236 NPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILR 295 P R+ A+L Sbjct: 225 PP-----------------------------------------------QQQRTGTALLT 237 Query: 296 VLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGA-ATESV 354 + + D NDN P F++ VY L ENS PGT ++QL A D D G NG++ Y F + + Sbjct: 238 IRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRA 297 Query: 355 RRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPS 414 R L L +G L V +D EE + V A+D G V++ + D NDN P Sbjct: 298 RELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPE 357 Query: 415 IEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPAS 474 I + V+E T +AL V+DRD ENG V C ++GDVPF+LK + Sbjct: 358 ISFSTVKEA--------VSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSF 409 Query: 475 DTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPM 534 K Y + T PLD EA + + +VA D G P+LS++ S+ V+V D NDN P Sbjct: 410 -------KNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPR 462 Query: 535 FGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSL------DSSVMGIFAIDPDS 588 F Q V +VY ENN+PG + V ATD D G NA++AYS+ SV +I+ ++ Sbjct: 463 FSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSEN 522 Query: 589 GDILVNTVLDREQTDRYEFKVNAKDKGIP-VLQGSTTVIVQVADKNDNDPKFMQDV---- 643 G + D EQ + F+V A+D G P L G+ TV + + D+NDN P + + Sbjct: 523 GYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRN 582 Query: 644 ---FTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIFSIENDTGTIYST- 697 + + +P + V +DAD G NA ++ I N N+F ++ TG + + Sbjct: 583 GTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTAR 642 Query: 698 -MSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMD 734 + R+ Q Y ++ D G PP S+TAT+ + ++D Sbjct: 643 RVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680 Score = 234 bits (597), Expect = 3e-61 Identities = 192/660 (29%), Positives = 310/660 (46%), Gaps = 66/660 (10%) Query: 294 LRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATES 353 + + + D+NDN P F + +++E++ PGT A D DVG N +Y + Sbjct: 108 VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEI-----T 162 Query: 354 VRRLLRLD-ETSG------WLSVLHRIDREEVNQLRFTVMARDRG--------------- 391 LD +T G L + +DRE+ R+ + A D G Sbjct: 163 PNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGA 222 Query: 392 ----QPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQV 447 Q +T A + + + D NDNVP+ + ++ E+ T + + Sbjct: 223 GLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVY--------TVSLPENSPPGTLVIQLNA 274 Query: 448 SDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVA 507 +D D+G+NG VV + P + + + L S LDYE + + V + A Sbjct: 275 TDPDEGQNG----EVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQA 330 Query: 508 VDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKN 567 D G ++ ++ ++V+V D NDN P S V+ E PG VA TD DS +N Sbjct: 331 KDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEEN 390 Query: 568 AEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626 ++ L V + + + I+ LDRE D Y V A+D+G P L S ++ Sbjct: 391 GQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQ 450 Query: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEE----NN 682 VQV+D NDN P+F Q V+ YV EN P + + V+ D D+G NA+++ I E Sbjct: 451 VQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGM 510 Query: 683 NIF---SIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSA-TATVSLFVMDENDN 738 ++F SI ++ G +Y+ SFD E ++F+V+A D G P A ATV++ ++D+NDN Sbjct: 511 SVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDN 570 Query: 739 APTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFE 793 AP + P + +LP S+ ++ V A D+DDG NA L YSIV GN LF Sbjct: 571 APAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFR 630 Query: 794 IDPTSGVVSLVGKLTQKH--YGLHRLVVQVNDSGQPS-QSTTTLVHVFVNESVSNATAID 850 +D +G + ++ K + LV++V D GQP ST TLV V+ +V Sbjct: 631 MDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGG 690 Query: 851 SQIARS-LHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNK 909 S S H ++ G+ S + L++++ + G ++ I ++ ++V+A C+ + K Sbjct: 691 SGGGGSGEHQRPSRSGGGETSLD-----LTLILIIALGSVSFIFLLAMIVLAVRCQKEKK 745 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.133 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 42,454,780 Number of Sequences: 37866 Number of extensions: 2172977 Number of successful extensions: 24929 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 344 Number of HSP's successfully gapped in prelim test: 233 Number of HSP's that attempted gapping in prelim test: 9939 Number of HSP's gapped (non-prelim): 4994 length of query: 1069 length of database: 18,247,518 effective HSP length: 113 effective length of query: 956 effective length of database: 13,968,660 effective search space: 13354038960 effective search space used: 13354038960 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.