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Search of human proteins with 145312267
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|145312267 transcription factor 4 isoform a [Homo sapiens]
(671 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|145312267 transcription factor 4 isoform a [Homo sapiens] 1370 0.0
gi|4507399 transcription factor 4 isoform b [Homo sapiens] 1357 0.0
gi|46370084 transcription factor 12 isoform b [Homo sapiens] 809 0.0
gi|4507391 transcription factor 12 isoform b [Homo sapiens] 809 0.0
gi|46370082 transcription factor 12 isoform a [Homo sapiens] 795 0.0
gi|46370080 transcription factor 12 isoform a [Homo sapiens] 795 0.0
gi|46370086 transcription factor 12 isoform c [Homo sapiens] 612 e-175
gi|27777636 transcription factor 3 isoform E12 [Homo sapiens] 583 e-166
gi|209915594 transcription factor 3 isoform E47 [Homo sapiens] 562 e-160
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 58 3e-08
gi|57864582 hornerin [Homo sapiens] 55 3e-07
gi|60097902 filaggrin [Homo sapiens] 49 2e-05
gi|62122917 filaggrin family member 2 [Homo sapiens] 48 3e-05
gi|28559039 mediator complex subunit 1 [Homo sapiens] 47 7e-05
gi|121114306 neurogenic differentiation 1 [Homo sapiens] 46 1e-04
gi|167736355 mucin 4 isoform a [Homo sapiens] 46 1e-04
gi|239756681 PREDICTED: basic helix-loop-helix family, member a9... 45 3e-04
gi|239751178 PREDICTED: basic helix-loop-helix family, member a9... 45 3e-04
gi|239745666 PREDICTED: basic helix-loop-helix family, member a9... 45 3e-04
gi|98986461 neurogenic differentiation 2 [Homo sapiens] 44 4e-04
gi|5453726 leucine rich repeat (in FLII) interacting protein 2 i... 44 5e-04
gi|7662230 ring finger protein 40 [Homo sapiens] 44 5e-04
gi|226498192 atonal homolog 8 [Homo sapiens] 44 6e-04
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s... 43 0.001
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens] 43 0.001
gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens] 43 0.001
gi|4885075 atonal homolog 1 [Homo sapiens] 42 0.001
gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens] 42 0.001
gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens] 42 0.001
gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo ... 42 0.002
>gi|145312267 transcription factor 4 isoform a [Homo sapiens]
Length = 671
Score = 1370 bits (3546), Expect = 0.0
Identities = 671/671 (100%), Positives = 671/671 (100%)
Query: 1 MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWG 60
MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWG
Sbjct: 1 MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWG 60
Query: 61 NGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQG 120
NGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQG
Sbjct: 61 NGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQG 120
Query: 121 CHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGL 180
CHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGL
Sbjct: 121 CHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGL 180
Query: 181 PSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAG 240
PSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAG
Sbjct: 181 PSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAG 240
Query: 241 MLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPA 300
MLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPA
Sbjct: 241 MLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPA 300
Query: 301 NGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTA 360
NGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTA
Sbjct: 301 NGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTA 360
Query: 361 VWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHG 420
VWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHG
Sbjct: 361 VWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHG 420
Query: 421 IIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQ 480
IIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQ
Sbjct: 421 IIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQ 480
Query: 481 SATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKD 540
SATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKD
Sbjct: 481 SATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKD 540
Query: 541 IKSITRSRSSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLK 600
IKSITRSRSSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLK
Sbjct: 541 IKSITRSRSSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLK 600
Query: 601 SDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPG 660
SDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPG
Sbjct: 601 SDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPG 660
Query: 661 MGDASNHMGQM 671
MGDASNHMGQM
Sbjct: 661 MGDASNHMGQM 671
>gi|4507399 transcription factor 4 isoform b [Homo sapiens]
Length = 667
Score = 1357 bits (3513), Expect = 0.0
Identities = 667/671 (99%), Positives = 667/671 (99%), Gaps = 4/671 (0%)
Query: 1 MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWG 60
MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWG
Sbjct: 1 MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWG 60
Query: 61 NGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQG 120
NGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQG
Sbjct: 61 NGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQG 120
Query: 121 CHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGL 180
CHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGL
Sbjct: 121 CHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGL 180
Query: 181 PSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAG 240
PSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAG
Sbjct: 181 PSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAG 240
Query: 241 MLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPA 300
MLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPA
Sbjct: 241 MLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPA 300
Query: 301 NGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTA 360
NGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTA
Sbjct: 301 NGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTA 360
Query: 361 VWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHG 420
VWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHG
Sbjct: 361 VWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHG 420
Query: 421 IIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQ 480
IIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQ
Sbjct: 421 IIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQ 480
Query: 481 SATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKD 540
SATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKD
Sbjct: 481 SATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKD 540
Query: 541 IKSITRSRSSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLK 600
IKSIT SNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLK
Sbjct: 541 IKSIT----SNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLK 596
Query: 601 SDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPG 660
SDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPG
Sbjct: 597 SDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPG 656
Query: 661 MGDASNHMGQM 671
MGDASNHMGQM
Sbjct: 657 MGDASNHMGQM 667
>gi|46370084 transcription factor 12 isoform b [Homo sapiens]
Length = 682
Score = 809 bits (2089), Expect = 0.0
Identities = 441/692 (63%), Positives = 531/692 (76%), Gaps = 38/692 (5%)
Query: 4 QQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGG 63
QQRMAA+GTDKELSDLLDFSAMFSPPV+SGK PT+L S F+GS +++R + SWG G
Sbjct: 5 QQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSG 64
Query: 64 HPSPS----RNYGDGTPY-DHMTSRDLGSHDNLSP-PFVNSRIQSKT-ERGSYSSYGRES 116
PSPS R + D Y DH+ LG+H+ LSP PF+NS + KT ERGS+S Y R++
Sbjct: 65 QPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDT 124
Query: 117 NLQGCHQQSLLGGDMDMGNPGTLSPT-KPGSQYYQYSSNNPRRRPLHSSAM--EVQTKKV 173
L GC Q SLL D+ +G+P LS + KPG+ YY +S+ + RRRPLH SA +Q KKV
Sbjct: 125 GLPGC-QSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKV 183
Query: 174 RKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDG-HHSSDPWSSSSG 232
RKVPPGLPSSVYAPS ++ D+NR+SP YPS KP TS F S+FFMQDG H+SSD WSSS+G
Sbjct: 184 RKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNG 243
Query: 233 MNQPGYAGMLGNS-SHIPQSSSYCSLHPHERLSYPSHSSA--DINSSLPPMSTFHRSGTN 289
M+QPG+ G+LG S SH+ QSSSY +LH H+RLSYP HS + DIN+SLPPMS+FHR T+
Sbjct: 244 MSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTS 303
Query: 290 H--YSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPST 347
Y +S TPP NG+DSI+ RG+ AAGSSQTGDALGKALASIYSPDHT++SF SNPST
Sbjct: 304 SSPYVAASHTPPINGSDSILGTRGN-AAGSSQTGDALGKALASIYSPDHTSSSFPSNPST 362
Query: 348 PVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGP 407
PVGSP L+ GT+ W R GGQA SSP+YE LHSLQSR+EDRL+RLDDAIHVLRNHAVGP
Sbjct: 363 PVGSPSPLT-GTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGP 421
Query: 408 STAMPGGHGDMHGIIGPSHNGAMGGLGSGYG-TGLLSANRHSLMVGTHREDGVALRGSHS 466
ST++P GH D+H ++GPSHN +G L S YG + L++++R + MVGTHRED V+L G+HS
Sbjct: 422 STSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHS 481
Query: 467 LLPNQVPVPQLPVQSATSPDLN-PPQDPYRGMPPGLQGQSVSSGSSEIKSDD-EGDENLQ 524
+L + V + +S DLN Q+ YRG GLQ QS + ++EIK+++ E DENL
Sbjct: 482 VLSSTV--------TTSSTDLNHKTQENYRG---GLQSQSGTVVTTEIKTENKEKDENLH 530
Query: 525 DTKSSEDKKLDDD--KKDIKSITRSR-SSNNDDEDLTPEQKAEREKERRMANNARERLRV 581
+ SS+D K DD+ +KDIK +R R SS N+DEDL PEQK EREKERRMANNARERLRV
Sbjct: 531 EPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRV 590
Query: 582 RDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRRE 641
RDINEAFKELGRM QLHLKS+KPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRRE
Sbjct: 591 RDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRRE 650
Query: 642 EEKVS--SEPPPLSLAGPHPGMGDASNHMGQM 671
EEKVS S PP +L G HPG+ + +N MG M
Sbjct: 651 EEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM 682
>gi|4507391 transcription factor 12 isoform b [Homo sapiens]
Length = 682
Score = 809 bits (2089), Expect = 0.0
Identities = 441/692 (63%), Positives = 531/692 (76%), Gaps = 38/692 (5%)
Query: 4 QQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGG 63
QQRMAA+GTDKELSDLLDFSAMFSPPV+SGK PT+L S F+GS +++R + SWG G
Sbjct: 5 QQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSG 64
Query: 64 HPSPS----RNYGDGTPY-DHMTSRDLGSHDNLSP-PFVNSRIQSKT-ERGSYSSYGRES 116
PSPS R + D Y DH+ LG+H+ LSP PF+NS + KT ERGS+S Y R++
Sbjct: 65 QPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDT 124
Query: 117 NLQGCHQQSLLGGDMDMGNPGTLSPT-KPGSQYYQYSSNNPRRRPLHSSAM--EVQTKKV 173
L GC Q SLL D+ +G+P LS + KPG+ YY +S+ + RRRPLH SA +Q KKV
Sbjct: 125 GLPGC-QSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKV 183
Query: 174 RKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDG-HHSSDPWSSSSG 232
RKVPPGLPSSVYAPS ++ D+NR+SP YPS KP TS F S+FFMQDG H+SSD WSSS+G
Sbjct: 184 RKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNG 243
Query: 233 MNQPGYAGMLGNS-SHIPQSSSYCSLHPHERLSYPSHSSA--DINSSLPPMSTFHRSGTN 289
M+QPG+ G+LG S SH+ QSSSY +LH H+RLSYP HS + DIN+SLPPMS+FHR T+
Sbjct: 244 MSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTS 303
Query: 290 H--YSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPST 347
Y +S TPP NG+DSI+ RG+ AAGSSQTGDALGKALASIYSPDHT++SF SNPST
Sbjct: 304 SSPYVAASHTPPINGSDSILGTRGN-AAGSSQTGDALGKALASIYSPDHTSSSFPSNPST 362
Query: 348 PVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGP 407
PVGSP L+ GT+ W R GGQA SSP+YE LHSLQSR+EDRL+RLDDAIHVLRNHAVGP
Sbjct: 363 PVGSPSPLT-GTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGP 421
Query: 408 STAMPGGHGDMHGIIGPSHNGAMGGLGSGYG-TGLLSANRHSLMVGTHREDGVALRGSHS 466
ST++P GH D+H ++GPSHN +G L S YG + L++++R + MVGTHRED V+L G+HS
Sbjct: 422 STSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHS 481
Query: 467 LLPNQVPVPQLPVQSATSPDLN-PPQDPYRGMPPGLQGQSVSSGSSEIKSDD-EGDENLQ 524
+L + V + +S DLN Q+ YRG GLQ QS + ++EIK+++ E DENL
Sbjct: 482 VLSSTV--------TTSSTDLNHKTQENYRG---GLQSQSGTVVTTEIKTENKEKDENLH 530
Query: 525 DTKSSEDKKLDDD--KKDIKSITRSR-SSNNDDEDLTPEQKAEREKERRMANNARERLRV 581
+ SS+D K DD+ +KDIK +R R SS N+DEDL PEQK EREKERRMANNARERLRV
Sbjct: 531 EPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRV 590
Query: 582 RDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRRE 641
RDINEAFKELGRM QLHLKS+KPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRRE
Sbjct: 591 RDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRRE 650
Query: 642 EEKVS--SEPPPLSLAGPHPGMGDASNHMGQM 671
EEKVS S PP +L G HPG+ + +N MG M
Sbjct: 651 EEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM 682
>gi|46370082 transcription factor 12 isoform a [Homo sapiens]
Length = 706
Score = 795 bits (2054), Expect = 0.0
Identities = 441/716 (61%), Positives = 531/716 (74%), Gaps = 62/716 (8%)
Query: 4 QQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGG 63
QQRMAA+GTDKELSDLLDFSAMFSPPV+SGK PT+L S F+GS +++R + SWG G
Sbjct: 5 QQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSG 64
Query: 64 HPSPS----RNYGDGTPY-DHMTSRDLGSHDNLSP-PFVNSRIQSKT-ERGSYSSYGRES 116
PSPS R + D Y DH+ LG+H+ LSP PF+NS + KT ERGS+S Y R++
Sbjct: 65 QPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDT 124
Query: 117 NLQGCHQQSLLGGDMDMGNPGTLSPT-KPGSQYYQYSSNNPRRRPLHSSAM--EVQTKKV 173
L GC Q SLL D+ +G+P LS + KPG+ YY +S+ + RRRPLH SA +Q KKV
Sbjct: 125 GLPGC-QSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKV 183
Query: 174 RKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDG-HHSSDPWSSSSG 232
RKVPPGLPSSVYAPS ++ D+NR+SP YPS KP TS F S+FFMQDG H+SSD WSSS+G
Sbjct: 184 RKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNG 243
Query: 233 MNQPGYAGMLGNS-SHIPQSSSYCSLHPHERLSYPSHSSA--DINSSLPPMSTFHRSGTN 289
M+QPG+ G+LG S SH+ QSSSY +LH H+RLSYP HS + DIN+SLPPMS+FHR T+
Sbjct: 244 MSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTS 303
Query: 290 H--YSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPST 347
Y +S TPP NG+DSI+ RG+ AAGSSQTGDALGKALASIYSPDHT++SF SNPST
Sbjct: 304 SSPYVAASHTPPINGSDSILGTRGN-AAGSSQTGDALGKALASIYSPDHTSSSFPSNPST 362
Query: 348 PVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSL------------------------Q 383
PVGSP L+ GT+ W R GGQA SSP+YE LHSL Q
Sbjct: 363 PVGSPSPLT-GTSQWPRPGGQAPSSPSYENSLHSLKNRVEQQLHEHLQDAMSFLKDVCEQ 421
Query: 384 SRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYG-TGLL 442
SR+EDRL+RLDDAIHVLRNHAVGPST++P GH D+H ++GPSHN +G L S YG + L+
Sbjct: 422 SRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLV 481
Query: 443 SANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLN-PPQDPYRGMPPGL 501
+++R + MVGTHRED V+L G+HS+L + V + +S DLN Q+ YRG GL
Sbjct: 482 ASSRSASMVGTHREDSVSLNGNHSVLSSTV--------TTSSTDLNHKTQENYRG---GL 530
Query: 502 QGQSVSSGSSEIKSDD-EGDENLQDTKSSEDKKLDDD--KKDIKSITRSR-SSNNDDEDL 557
Q QS + ++EIK+++ E DENL + SS+D K DD+ +KDIK +R R SS N+DEDL
Sbjct: 531 QSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDL 590
Query: 558 TPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAV 617
PEQK EREKERRMANNARERLRVRDINEAFKELGRM QLHLKS+KPQTKLLILHQAVAV
Sbjct: 591 NPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAV 650
Query: 618 ILSLEQQVRERNLNPKAACLKRREEEKVS--SEPPPLSLAGPHPGMGDASNHMGQM 671
ILSLEQQVRERNLNPKAACLKRREEEKVS S PP +L G HPG+ + +N MG M
Sbjct: 651 ILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM 706
>gi|46370080 transcription factor 12 isoform a [Homo sapiens]
Length = 706
Score = 795 bits (2054), Expect = 0.0
Identities = 441/716 (61%), Positives = 531/716 (74%), Gaps = 62/716 (8%)
Query: 4 QQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGG 63
QQRMAA+GTDKELSDLLDFSAMFSPPV+SGK PT+L S F+GS +++R + SWG G
Sbjct: 5 QQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSG 64
Query: 64 HPSPS----RNYGDGTPY-DHMTSRDLGSHDNLSP-PFVNSRIQSKT-ERGSYSSYGRES 116
PSPS R + D Y DH+ LG+H+ LSP PF+NS + KT ERGS+S Y R++
Sbjct: 65 QPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDT 124
Query: 117 NLQGCHQQSLLGGDMDMGNPGTLSPT-KPGSQYYQYSSNNPRRRPLHSSAM--EVQTKKV 173
L GC Q SLL D+ +G+P LS + KPG+ YY +S+ + RRRPLH SA +Q KKV
Sbjct: 125 GLPGC-QSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKV 183
Query: 174 RKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDG-HHSSDPWSSSSG 232
RKVPPGLPSSVYAPS ++ D+NR+SP YPS KP TS F S+FFMQDG H+SSD WSSS+G
Sbjct: 184 RKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNG 243
Query: 233 MNQPGYAGMLGNS-SHIPQSSSYCSLHPHERLSYPSHSSA--DINSSLPPMSTFHRSGTN 289
M+QPG+ G+LG S SH+ QSSSY +LH H+RLSYP HS + DIN+SLPPMS+FHR T+
Sbjct: 244 MSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTS 303
Query: 290 H--YSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPST 347
Y +S TPP NG+DSI+ RG+ AAGSSQTGDALGKALASIYSPDHT++SF SNPST
Sbjct: 304 SSPYVAASHTPPINGSDSILGTRGN-AAGSSQTGDALGKALASIYSPDHTSSSFPSNPST 362
Query: 348 PVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSL------------------------Q 383
PVGSP L+ GT+ W R GGQA SSP+YE LHSL Q
Sbjct: 363 PVGSPSPLT-GTSQWPRPGGQAPSSPSYENSLHSLKNRVEQQLHEHLQDAMSFLKDVCEQ 421
Query: 384 SRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYG-TGLL 442
SR+EDRL+RLDDAIHVLRNHAVGPST++P GH D+H ++GPSHN +G L S YG + L+
Sbjct: 422 SRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLV 481
Query: 443 SANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLN-PPQDPYRGMPPGL 501
+++R + MVGTHRED V+L G+HS+L + V + +S DLN Q+ YRG GL
Sbjct: 482 ASSRSASMVGTHREDSVSLNGNHSVLSSTV--------TTSSTDLNHKTQENYRG---GL 530
Query: 502 QGQSVSSGSSEIKSDD-EGDENLQDTKSSEDKKLDDD--KKDIKSITRSR-SSNNDDEDL 557
Q QS + ++EIK+++ E DENL + SS+D K DD+ +KDIK +R R SS N+DEDL
Sbjct: 531 QSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDL 590
Query: 558 TPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAV 617
PEQK EREKERRMANNARERLRVRDINEAFKELGRM QLHLKS+KPQTKLLILHQAVAV
Sbjct: 591 NPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAV 650
Query: 618 ILSLEQQVRERNLNPKAACLKRREEEKVS--SEPPPLSLAGPHPGMGDASNHMGQM 671
ILSLEQQVRERNLNPKAACLKRREEEKVS S PP +L G HPG+ + +N MG M
Sbjct: 651 ILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM 706
>gi|46370086 transcription factor 12 isoform c [Homo sapiens]
Length = 512
Score = 612 bits (1579), Expect = e-175
Identities = 332/503 (66%), Positives = 397/503 (78%), Gaps = 27/503 (5%)
Query: 183 SVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDG-HHSSDPWSSSSGMNQPGYAGM 241
+VYAPS ++ D+NR+SP YPS KP TS F S+FFMQDG H+SSD WSSS+GM+QPG+ G+
Sbjct: 23 TVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGI 82
Query: 242 LGNS-SHIPQSSSYCSLHPHERLSYPSHSSA--DINSSLPPMSTFHRSGTNH--YSTSSC 296
LG S SH+ QSSSY +LH H+RLSYP HS + DIN+SLPPMS+FHR T+ Y +S
Sbjct: 83 LGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASH 142
Query: 297 TPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLS 356
TPP NG+DSI+ RG+ AAGSSQTGDALGKALASIYSPDHT++SF SNPSTPVGSP L+
Sbjct: 143 TPPINGSDSILGTRGN-AAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLT 201
Query: 357 AGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHG 416
GT+ W R GGQA SSP+YE LHSLQSR+EDRL+RLDDAIHVLRNHAVGPST++P GH
Sbjct: 202 -GTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHS 260
Query: 417 DMHGIIGPSHNGAMGGLGSGYG-TGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVP 475
D+H ++GPSHN +G L S YG + L++++R + MVGTHRED V+L G+HS+L + V
Sbjct: 261 DIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTV--- 317
Query: 476 QLPVQSATSPDLN-PPQDPYRGMPPGLQGQSVSSGSSEIKSDD-EGDENLQDTKSSEDKK 533
+ +S DLN Q+ YRG GLQ QS + ++EIK+++ E DENL + SS+D K
Sbjct: 318 -----TTSSTDLNHKTQENYRG---GLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMK 369
Query: 534 LDDD--KKDIKSITRSR-SSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKE 590
DD+ +KDIK +R R SS N+DEDL PEQK EREKERRMANNARERLRVRDINEAFKE
Sbjct: 370 SDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKE 429
Query: 591 LGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVS--SE 648
LGRM QLHLKS+KPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVS S
Sbjct: 430 LGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSA 489
Query: 649 PPPLSLAGPHPGMGDASNHMGQM 671
PP +L G HPG+ + +N MG M
Sbjct: 490 EPPTTLPGTHPGLSETTNPMGHM 512
>gi|27777636 transcription factor 3 isoform E12 [Homo sapiens]
Length = 654
Score = 583 bits (1502), Expect = e-166
Identities = 360/700 (51%), Positives = 463/700 (66%), Gaps = 75/700 (10%)
Query: 1 MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWG 60
M+ QRMA +GTDKELSDLLDFS MF PV++GK P SLA F GS +EDR SSGSWG
Sbjct: 1 MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWG 60
Query: 61 NGGHPS----PSRNYGDGTPYDHMTSRDLGSHDNLSPP-FVNSRIQSKT-ERGSYSSYGR 114
+G S PSR + +GT H T SH +LS F+ + K+ ERG+Y+S+GR
Sbjct: 61 SGDQSSSSFDPSRTFSEGT---HFTE----SHSSLSSSTFLGPGLGGKSGERGAYASFGR 113
Query: 115 ESNLQGCHQQSLLGGDMDMGNPGTLSPT--KPGSQYYQYSSNNPRRRPLHSSAMEVQTKK 172
++ + G Q L G++ + +PG LSP+ K SQYY S + RRR S ++ Q KK
Sbjct: 114 DAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGS-LDTQPKK 172
Query: 173 VRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDG--HHSSDPWSSS 230
VRKVPPGLPSSVY PS S DY RD+ YPS+K +ST+P+ F++ DG H S++ WS
Sbjct: 173 VRKVPPGLPSSVYPPS-SGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPP 231
Query: 231 SGMNQPGYAGMLGN-SSHIP------------QSSSYCSLHPHERLSYPSHSSADINSSL 277
Q G+ MLG SS +P SS++ LH HER+ Y H A++N L
Sbjct: 232 G---QAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHG-AEVNGGL 287
Query: 278 PPMSTFHRS-GTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDH 336
P S+F + G + SS TPP +G DS++ +RG+ AGSS GDALGKALASIYSPDH
Sbjct: 288 PSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGT-TAGSS--GDALGKALASIYSPDH 344
Query: 337 TNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDA 396
++N+FSS+PSTPVGSP L AGT+ W R G + SP+Y+G LH LQS+IED L D+A
Sbjct: 345 SSNNFSSSPSTPVGSPQGL-AGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHL---DEA 400
Query: 397 IHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVG-THR 455
IHVLR+HAVG + GDMH ++ P H G L SG+ + RH+ +VG +H
Sbjct: 401 IHVLRSHAVGTA-------GDMHTLL-PGH----GALASGFTGPMSLGGRHAGLVGGSHP 448
Query: 456 EDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKS 515
EDG+A GS SL+ N +P P T PDL+ P D Y G+ G G ++ +SEIK
Sbjct: 449 EDGLA--GSTSLMHNHAALPSQP---GTLPDLSRPPDSYSGL--GRAG--ATAAASEIKR 499
Query: 516 DDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDED--LTPEQKAEREKERRMAN 573
+++ DE ++T +++ +++KK++K+ R+R+S ++DED L PEQKAEREKERR+AN
Sbjct: 500 EEKEDE--ENTSAADHS--EEEKKELKA-PRARTSPDEDEDDLLPPEQKAEREKERRVAN 554
Query: 574 NARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPK 633
NARERLRVRDINEAFKELGRM QLHL S+KPQTKLLILHQAV+VIL+LEQQVRERNLNPK
Sbjct: 555 NARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRERNLNPK 614
Query: 634 AACLKRREEEKVSS--EPPPLSLAGPHPGMGDASNHMGQM 671
AACLKRREEEKVS P + L+ PHPG+ +A N G M
Sbjct: 615 AACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM 654
>gi|209915594 transcription factor 3 isoform E47 [Homo sapiens]
Length = 651
Score = 562 bits (1449), Expect = e-160
Identities = 351/698 (50%), Positives = 456/698 (65%), Gaps = 74/698 (10%)
Query: 1 MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWG 60
M+ QRMA +GTDKELSDLLDFS MF PV++GK P SLA F GS +EDR SSGSWG
Sbjct: 1 MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWG 60
Query: 61 NGGHPS----PSRNYGDGTPYDHMTSRDLGSHDNLSPP-FVNSRIQSKT-ERGSYSSYGR 114
+G S PSR + +GT H T SH +LS F+ + K+ ERG+Y+S+GR
Sbjct: 61 SGDQSSSSFDPSRTFSEGT---HFTE----SHSSLSSSTFLGPGLGGKSGERGAYASFGR 113
Query: 115 ESNLQGCHQQSLLGGDMDMGNPGTLSPT--KPGSQYYQYSSNNPRRRPLHSSAMEVQTKK 172
++ + G Q L G++ + +PG LSP+ K SQYY S + RRR S ++ Q KK
Sbjct: 114 DAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGS-LDTQPKK 172
Query: 173 VRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDG--HHSSDPWSSS 230
VRKVPPGLPSSVY PS S DY RD+ YPS+K +ST+P+ F++ DG H S++ WS
Sbjct: 173 VRKVPPGLPSSVYPPS-SGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPP 231
Query: 231 SGMNQPGYAGMLGN-SSHIP------------QSSSYCSLHPHERLSYPSHSSADINSSL 277
Q G+ MLG SS +P SS++ LH HER+ Y H A++N L
Sbjct: 232 G---QAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHG-AEVNGGL 287
Query: 278 PPMSTFHRS-GTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDH 336
P S+F + G + SS TPP +G DS++ +RG+ AGSS GDALGKALASIYSPDH
Sbjct: 288 PSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGT-TAGSS--GDALGKALASIYSPDH 344
Query: 337 TNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDA 396
++N+FSS+PSTPVGSP L AGT+ W R G + SP+Y+G LH LQS+IED L D+A
Sbjct: 345 SSNNFSSSPSTPVGSPQGL-AGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHL---DEA 400
Query: 397 IHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVG-THR 455
IHVLR+HAVG + GDMH ++ P H G L SG+ + RH+ +VG +H
Sbjct: 401 IHVLRSHAVGTA-------GDMHTLL-PGH----GALASGFTGPMSLGGRHAGLVGGSHP 448
Query: 456 EDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKS 515
EDG+A GS SL+ N +P P T PDL+ P D Y G+ G G ++ +SEIK
Sbjct: 449 EDGLA--GSTSLMHNHAALPSQP---GTLPDLSRPPDSYSGL--GRAG--ATAAASEIKR 499
Query: 516 DDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERRMANNA 575
+++ DE ++T +++ +++KK++K+ R+R+S+ D E L+ E+K R++ERRMANNA
Sbjct: 500 EEKEDE--ENTSAADHS--EEEKKELKA-PRARTSSTD-EVLSLEEKDLRDRERRMANNA 553
Query: 576 RERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAA 635
RER+RVRDINEAF+ELGRM Q+HLKSDK QTKLLIL QAV VIL LEQQVRERNLNPKAA
Sbjct: 554 RERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLEQQVRERNLNPKAA 613
Query: 636 CLKRREEEKVSS--EPPPLSLAGPHPGMGDASNHMGQM 671
CLKRREEEKVS P + L+ PHPG+ +A N G M
Sbjct: 614 CLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM 651
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 57.8 bits (138), Expect = 3e-08
Identities = 83/361 (22%), Positives = 137/361 (37%), Gaps = 19/361 (5%)
Query: 12 TDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNY 71
+D S+ D + S S N S S SN D S S N S S +
Sbjct: 716 SDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSD--SSNSSDSSDSSDSSNSSDSSDSSDS 773
Query: 72 GDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDM 131
D + + + + S+ + S NS S + S SS +S+ S
Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833
Query: 132 DMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSAST 191
D N S + S S+N S + + SS + S+ +
Sbjct: 834 DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD-----------SSNSSDSSDS 882
Query: 192 ADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQS 251
+D N S SS + S+ S + SSD S+SS ++ + NSS S
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS-SNSSDSSESSNSSDNSNSSDSSNS 941
Query: 252 SSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRG 311
S S S+SS NSS + + ++ +S+ + ++ +DS ++
Sbjct: 942 SDSSDSSDSSNSSDSSNSSDSSNSS----DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDS 997
Query: 312 SGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASS 371
S ++ SS + D+ + +S S D +N+S SSN S S S + + S + +S+
Sbjct: 998 SDSSNSSDSSDSSDSSDSS-NSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSN 1056
Query: 372 S 372
S
Sbjct: 1057 S 1057
Score = 56.2 bits (134), Expect = 9e-08
Identities = 102/548 (18%), Positives = 181/548 (33%), Gaps = 12/548 (2%)
Query: 17 SDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTP 76
SD D + S S + + S S+ D S S N + S S + D +
Sbjct: 617 SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676
Query: 77 YDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNP 136
+ S + S NS S + S S S+ + + +
Sbjct: 677 SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736
Query: 137 GTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNR 196
+ S S SS++ +S+ + SS S++++D +
Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSD 796
Query: 197 DSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCS 256
S SS + S+ S D +SSD +SS + + +S S S S
Sbjct: 797 SSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS 856
Query: 257 LHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAG 316
S S S+D ++S + + +++ S SS + ++ +DS ++ S ++
Sbjct: 857 NRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916
Query: 317 SSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYE 376
SS + D + S S D++N+S SSN S S S ++ + S + +S S +
Sbjct: 917 SSNSSD----SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972
Query: 377 GPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSG 436
S S D + D + + + S + S N + S
Sbjct: 973 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032
Query: 437 YGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRG 496
S++ + D S + S+ S D + D
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS--------DSSDSSDSSDSSDSSES 1084
Query: 497 MPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDED 556
S S S SD + D+ S D D D + S S+N +
Sbjct: 1085 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 1144
Query: 557 LTPEQKAE 564
+ ++
Sbjct: 1145 SDSSESSD 1152
Score = 55.1 bits (131), Expect = 2e-07
Identities = 108/530 (20%), Positives = 180/530 (33%), Gaps = 27/530 (5%)
Query: 31 SSGKNGPTSLASGHFTGSNVEDRSSSG---SWGNGGHPSPSRNYGDGTPYDHMTSRDLGS 87
+S N S +G+ G++ D+S SG S + S S N D + S D S
Sbjct: 518 TSDTNNSDSNGNGN-NGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS 576
Query: 88 HDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQ 147
+ +S S ++ S+ S+ S D + + S +
Sbjct: 577 SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDS 636
Query: 148 YYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPA 207
+ S++ ++ + SS + S+S++D + S SS +
Sbjct: 637 DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696
Query: 208 TSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPS 267
S+ S SSD SS+ + + +SS SS S S
Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756
Query: 268 HSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKA 327
SS NSS S+ ++ ++S +N +DS ++ S ++ SS + D+ +
Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816
Query: 328 LASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIE 387
D +N+S SSN S S S + + S +G + SS + S S
Sbjct: 817 -----DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSS 871
Query: 388 DRLERLDDAIHVLRNHAVGPSTAMPGGH---GDMHGIIGPSHNGAMGGLGSGYGTGLLSA 444
D D + N + S + + D S + + S
Sbjct: 872 DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931
Query: 445 NRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQ 504
N +S + + S+S S+ S D + D
Sbjct: 932 NSNSSDSSNSSDSSDSSDSSNS------------SDSSNSSDSSNSSDSSDSNSSDSSDS 979
Query: 505 SVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDD 554
S SS SS+ SD + D+ +S D D D S S SSN+ D
Sbjct: 980 SNSSDSSD-SSDSSDSSDSSDSSNSSDSSDSSDSSD--SSNSSDSSNSSD 1026
Score = 51.6 bits (122), Expect = 2e-06
Identities = 79/356 (22%), Positives = 130/356 (36%), Gaps = 12/356 (3%)
Query: 17 SDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTP 76
SD D S S S N S S + + S+ SS GS + + S S N D +
Sbjct: 810 SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD 869
Query: 77 YDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNP 136
++ S + S NS S + S S SN S + N
Sbjct: 870 SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929
Query: 137 GTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNR 196
S + S S ++ SS + S + ++S + +
Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989
Query: 197 DSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCS 256
DS S ++++ SS D SSD +SS N +SS+ SS
Sbjct: 990 DSSDSSDSSDSSNSSDSS----DSSDSSDSSNSSDSSNS-------SDSSNSSDSSDSSD 1038
Query: 257 LHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAG 316
S S SS NSS S+ ++ +S + + +DS ++ S ++
Sbjct: 1039 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSD 1098
Query: 317 SSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSS 372
SS + D+ + +S S D +++S SS+ S S S + + S + ++S S
Sbjct: 1099 SSDSSDSSDSSDSS-DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS 1153
Score = 47.0 bits (110), Expect = 6e-05
Identities = 77/382 (20%), Positives = 134/382 (35%), Gaps = 8/382 (2%)
Query: 197 DSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCS 256
DS SS + S+ S D + SSD SS S + + +S+ S S S
Sbjct: 551 DSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDS 610
Query: 257 LHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAG 316
+ S S + +S ++ ++S + ++ +DS ++ S ++
Sbjct: 611 SDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSD 670
Query: 317 SSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYE 376
SS + D+ + +S S D +++S SSN S S S + ++ S + SS +
Sbjct: 671 SSDSSDSSSSSDSS-NSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSS 729
Query: 377 GPLHSLQS-RIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGS 435
S S D + D + + + S + S N + S
Sbjct: 730 NSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSS 789
Query: 436 GYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYR 495
S+N + D S S + S+ S D + D
Sbjct: 790 NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849
Query: 496 GMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDE 555
G +S SS SS+ SD N D+ S D + D S SSN+ D
Sbjct: 850 GSDSDSSNRSDSSNSSD-SSDSSDSSNSSDSSDSSDSNESSNSSD-----SSDSSNSSDS 903
Query: 556 DLTPEQKAEREKERRMANNARE 577
D + + + ++++ E
Sbjct: 904 DSSDSSNSSDSSDSSNSSDSSE 925
Score = 47.0 bits (110), Expect = 6e-05
Identities = 75/342 (21%), Positives = 125/342 (36%), Gaps = 14/342 (4%)
Query: 31 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 90
+ N S S + + S+ D S+S + + S S + + + + S +
Sbjct: 886 NESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS 945
Query: 91 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 150
S NS S + S SS +SN S D + S + S
Sbjct: 946 DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN--- 1002
Query: 151 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 210
SS++ S+ + SS + S+ ++D + S SS + S+
Sbjct: 1003 -SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061
Query: 211 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS 270
S D SSD S SS ++ + NSS SS S S SS
Sbjct: 1062 DSSD--SSDSSDSSDS-SDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 271 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS 330
NSS S+ ++ ++S + + +DS ++ S ++ SS + D S
Sbjct: 1119 DSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSD-------S 1171
Query: 331 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSS 372
S D +N+S SS+ S S S + + S + +S S
Sbjct: 1172 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1213
Score = 44.3 bits (103), Expect = 4e-04
Identities = 113/531 (21%), Positives = 176/531 (33%), Gaps = 37/531 (6%)
Query: 49 NVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGS-HDNLSPPFVNSRIQSKTERG 107
N D S+ N + S + GD + Y+ S+D G+ D+ +S S T
Sbjct: 466 NSSDESNGNDDANSESDNNSSSRGDAS-YNSDESKDNGNGSDSKGAEDDDSDSTSDTNNS 524
Query: 108 SYSSYGRESNLQGCHQQSLLG----GDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHS 163
+ G N S G D D + S + S SN S
Sbjct: 525 DSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSN--------S 576
Query: 164 SAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHS 223
S+ + SS + S+ ++D + S SS + S SS D
Sbjct: 577 SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS-D 635
Query: 224 SDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTF 283
SD S SS N + +S S+S S + S S SS+D ++S +
Sbjct: 636 SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSD--SSDSSSSSDSSNSSDSSDSS 693
Query: 284 HRSGTNHYSTSSCTPPANGTDSI-MANRGSGAAGSSQTGDALGKALA------------- 329
S ++ S SS + ++ +DS +N S + SS + D+ + +
Sbjct: 694 DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS 753
Query: 330 -SIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIED 388
S S D +N+S SS+ S S S ++ + S N +S S N +S S
Sbjct: 754 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS 813
Query: 389 RLERLD-----DAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLS 443
D D+ + + S+ G S N + S S
Sbjct: 814 DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873
Query: 444 ANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQG 503
+N + + S + S+ S D + D
Sbjct: 874 SNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNS 933
Query: 504 QSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDD 554
S S +S SD N D+ +S D D D S S SSN+ D
Sbjct: 934 NSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD 984
Score = 44.3 bits (103), Expect = 4e-04
Identities = 76/342 (22%), Positives = 131/342 (38%), Gaps = 14/342 (4%)
Query: 31 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 90
+S + +S +S SN D S+S N S S + + + D S D + +
Sbjct: 910 NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS--DSSNSSDSSNSSD 967
Query: 91 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 150
S NS S + S SS +S+ S D + + S S
Sbjct: 968 SSDS--NSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS 1025
Query: 151 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 210
SSN+ S+ + SS + S+ ++D + S SS + S+
Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESS 1085
Query: 211 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS 270
S D +SSD SS + + +SS SS + S S SS
Sbjct: 1086 DSS-----DSSNSSDSSDSSDSSDSSDSS----DSSDSSDSSDSSNSSDSSDSSDSSDSS 1136
Query: 271 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS 330
NSS S+ ++ +S + ++ +DS ++ S ++ SS + D+ + +S
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196
Query: 331 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSS 372
S D +++S SS+ S S S + + S + ++S S
Sbjct: 1197 -DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237
Score = 42.4 bits (98), Expect = 0.001
Identities = 74/351 (21%), Positives = 126/351 (35%), Gaps = 16/351 (4%)
Query: 31 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 90
S+ + S +S SN D S S + S S N D + + S +
Sbjct: 963 SNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSS 1022
Query: 91 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 150
S NS S + S SS +S+ S D + + S S
Sbjct: 1023 NSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1082
Query: 151 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 210
SS++ S+ + SS + S++++D + S SS + S+
Sbjct: 1083 ESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 1142
Query: 211 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS 270
S D SSD SS + + +S S+S S + S S S
Sbjct: 1143 DSS-----DSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD--SSDSSDS 1195
Query: 271 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS 330
+D + S + S ++ S SS + ++ +DS +N S ++ SS + D S
Sbjct: 1196 SDSSDSSDSSDSSDSSDSSDSSDSSDS--SDSSDSSDSNESSDSSDSSDSSD-------S 1246
Query: 331 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHS 381
S D +++S SS+ ++ + + + NG + S HS
Sbjct: 1247 SNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHS 1297
Score = 41.6 bits (96), Expect = 0.002
Identities = 75/347 (21%), Positives = 123/347 (35%), Gaps = 10/347 (2%)
Query: 31 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 90
S + S S + S+ SS S N S S N D + + S +
Sbjct: 942 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001
Query: 91 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 150
S +S S + S SS +S+ S D + + S S
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061
Query: 151 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 210
SS++ S+ + + SS + S+ ++D + S SS + S+
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121
Query: 211 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS 270
S D SSD SS N + +S S S S + S S SS
Sbjct: 1122 NSS-----DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDS-SDSSDSS 1175
Query: 271 ADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALAS 330
NSS S+ ++ +S + ++ +DS ++ S ++ SS + D+ S
Sbjct: 1176 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD----S 1231
Query: 331 IYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEG 377
S D +++S SS+ S S S + + N S S + G
Sbjct: 1232 NESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNG 1278
Score = 29.6 bits (65), Expect = 9.4
Identities = 46/187 (24%), Positives = 72/187 (38%), Gaps = 21/187 (11%)
Query: 380 HSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGT 439
H R+E+R+ + + HAVG S I GPS G G
Sbjct: 349 HRESKRVENRITKESET------HAVGKS------QDKGIEIKGPSSGNRNITKEVGKGN 396
Query: 440 -GLLSANRHSLMVGTHREDGVALRGSHSLL--PNQVPVPQLPV-QSATSPDLNPP-QDPY 494
G +H +++G + V +G + P Q P V S T D N D Y
Sbjct: 397 EGKEDKGQHGMILG---KGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSY 453
Query: 495 RGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLD-DDKKDIKSITRSRSSNND 553
+QG +S +DD E+ ++ S D + D+ KD + + S+ + +D
Sbjct: 454 DFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDD 513
Query: 554 DEDLTPE 560
D D T +
Sbjct: 514 DSDSTSD 520
Score = 29.6 bits (65), Expect = 9.4
Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 6/69 (8%)
Query: 504 QSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSN------NDDEDL 557
+S ++ SS + DE+ + S+ K +DD D S T + SN NDD D
Sbjct: 480 ESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDK 539
Query: 558 TPEQKAERE 566
+ K + +
Sbjct: 540 SDSGKGKSD 548
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 54.7 bits (130), Expect = 3e-07
Identities = 105/418 (25%), Positives = 154/418 (36%), Gaps = 45/418 (10%)
Query: 34 KNGPTSLASGHFT--GSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDNL 91
++G +S +S H+ GS S G G+G SPSR G+ H +S G H +
Sbjct: 1208 RHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGR-HGSGLGHSSSH--GQHGSG 1264
Query: 92 SPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQY 151
S + RG Y S S++ G H+ G+ S GS ++
Sbjct: 1265 SG--------RSSSRGPYESRSGHSSVFGQHESG-------SGHSSAYSQHGSGSGHFCS 1309
Query: 152 SSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPS-SKPATST 210
+ S+ + + + G S + S+ + S PS + + +
Sbjct: 1310 QGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGS 1369
Query: 211 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQS--SSYCSLH---PHERLSY 265
SS + Q H S WSSSSG + G G H S SS C+ H SY
Sbjct: 1370 GHSSSYGQ--HGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSY 1427
Query: 266 PSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMAN----RGSGAAGSSQTG 321
H S S S R G++ S+SS +G+ + + GSG + S G
Sbjct: 1428 EQHGSRSGQS-----SRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG 1482
Query: 322 -DALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLH 380
G +S YSP + + +SS+ P S S S+G GQ+S +
Sbjct: 1483 RHGSGSGQSSSYSPYGSGSGWSSSRG-PYESGSSHSSGLGHRESRSGQSSGYGQHGS--S 1539
Query: 381 SLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYG 438
S S + H G S+ HG HG G S + G GSG G
Sbjct: 1540 SGHSSTHGQHGSTSGQSSSCGQH--GASSGQSSSHG-QHG-SGSSQSSGYGRQGSGSG 1593
Score = 53.1 bits (126), Expect = 8e-07
Identities = 89/365 (24%), Positives = 123/365 (33%), Gaps = 34/365 (9%)
Query: 32 SGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGD-GTPYDHMTSRDL-GSHD 89
SG++ S S + N + SSG G S NYG G+ +S D GS
Sbjct: 166 SGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGS 225
Query: 90 NLSPPFVNSRIQSKTERGSYSSYGRES-NLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQY 148
S F + S G YS +G S + G Q G G S + S Y
Sbjct: 226 GQSSGFSQHKSSSGQSSG-YSQHGSGSGHSSGYGQHGSRSGQSSRGERHR-SSSGSSSSY 283
Query: 149 YQYSSNNPRR--RPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKP 206
Q+ S + + S VR SS + S + Y+ Y S
Sbjct: 284 GQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSG 343
Query: 207 ATSTFPSSFFMQDGHHSSDPWSSS------SGMNQPGYAGMLGNSSHIPQSSSYCSLHPH 260
TS F G H S SS SG G G++S SS
Sbjct: 344 QTSGF--------GQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSR 395
Query: 261 ERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQT 320
+ SY H SA +SS H SG+ +G G+G SS +
Sbjct: 396 QSSSYGQHESASRHSSGRGQ---HSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSS 452
Query: 321 GDALGKA----------LASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQAS 370
G + + +S +S +T + S S+ G S S ++ R G A
Sbjct: 453 GPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAG 512
Query: 371 SSPNY 375
SS +Y
Sbjct: 513 SSSSY 517
Score = 51.6 bits (122), Expect = 2e-06
Identities = 103/416 (24%), Positives = 155/416 (37%), Gaps = 41/416 (9%)
Query: 34 KNGPTSLASGHFT--GSNVEDRSSSGSWGNGGHPSPSRN-YGDGTPYDHMTSRDLGSHDN 90
++G +S +S + GS S G G+G SPSR +G G+ + S G H +
Sbjct: 2148 RHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGH----SSSHGQHGS 2203
Query: 91 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 150
S + RG Y S S++ G H+ G+ S GS ++
Sbjct: 2204 GSG--------RSSSRGPYESRSGHSSVFGQHESG-------SGHSSAYSQHGSGSGHFC 2248
Query: 151 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPS-SKPATS 209
+ S+ + + + G S + S+S S PS + +
Sbjct: 2249 SQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSG 2308
Query: 210 TFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHS 269
+ SS + Q H S WSSSSG + G G H +SSS+ S + S HS
Sbjct: 2309 SGHSSSYGQ--HGSGSGWSSSSGRHGSGSGQSSGFGHH--ESSSWQSSGYTQHGSGSGHS 2364
Query: 270 SA--DINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMAN----RGSGAAGSSQTG-D 322
S+ S S R G++ S+SS +G+ + + GSG + S G
Sbjct: 2365 SSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 2424
Query: 323 ALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSL 382
G +S YSP + + +SS+ P S S+G GQ+S + S
Sbjct: 2425 GSGSGQSSSYSPYGSGSGWSSSRG-PYESGSGHSSGLGHRESRSGQSSGYGQHGS--SSG 2481
Query: 383 QSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYG 438
S + H G S+ HG HG G S + G GSG G
Sbjct: 2482 HSSTHGQHGSTSGQSSSCGQH--GASSGQSSSHG-QHG-SGSSQSSGYGRQGSGSG 2533
Score = 49.3 bits (116), Expect = 1e-05
Identities = 104/438 (23%), Positives = 143/438 (32%), Gaps = 45/438 (10%)
Query: 32 SGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDNL 91
S G SG ++ SN S SG GH S S + + +S G +
Sbjct: 672 SSSYGQHGSGSG-WSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHG 730
Query: 92 SPPFVNSRI-QSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 150
S +SR Q + G SSYG+ + G HQ S G G+ S P +
Sbjct: 731 SRSGQSSRSEQHGSSSGLSSSYGQHGS--GSHQSS------GHGRQGSGSGHSPSRVRHG 782
Query: 151 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 210
SS + H S + +S + S + GY A+
Sbjct: 783 SSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGS-----GQGYSQHGSASGH 837
Query: 211 FPSSFFMQDGHHSSDPWSSSSGMNQP--GYAGMLGNSSHIPQSSSYCSLHPHERLSYPSH 268
F S Q H S+ SSSSG + G + G +S H P H
Sbjct: 838 FSS----QGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGH 893
Query: 269 SSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKAL 328
S P H SG+ S+S +G S ++ S S T G
Sbjct: 894 GQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGH 953
Query: 329 ASIY------------SPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYE 376
+S Y S H ++S SS+ GS S G GQ+ S
Sbjct: 954 SSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGR 1013
Query: 377 GPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSG 436
S QS + R+ + S+ P G H G H + G SG
Sbjct: 1014 HGSGSGQS----------SSYGPYRSGSGWSSSRGPYESGSGHS-SGLGHRESRSGQSSG 1062
Query: 437 YGTGLLSANRHSLMVGTH 454
YG S++ HS G H
Sbjct: 1063 YGQH-GSSSGHSSTHGQH 1079
Score = 47.8 bits (112), Expect = 3e-05
Identities = 106/416 (25%), Positives = 146/416 (35%), Gaps = 68/416 (16%)
Query: 31 SSGKNGPTSLASGHFT--GSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSH 88
S G++G TS S F GS+ SS G G+G S S +YG GS
Sbjct: 1779 SQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGS--SQSSSYGQQ-----------GSG 1825
Query: 89 DNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLL---GGDMDMGNPGTLSPTKPG 145
SP SR + + G SSYG+ + G S G G S +
Sbjct: 1826 SGQSP----SRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS 1881
Query: 146 SQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSK 205
S Y Q+ S + HSS+ E + + G + S S++ Y + G S
Sbjct: 1882 SGYTQHGSGSG-----HSSSYEQHGSRSGQSSRGEQHG--SSSGSSSSYGQHGSGSRQS- 1933
Query: 206 PATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSY 265
+ G H S SG + G G+ S QSSSY
Sbjct: 1934 -----------LGHGQHGS-----GSGQSPSPSRGRHGSGSG--QSSSYG---------- 1965
Query: 266 PSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALG 325
P S + +SS P + SG+ H S +G S GS + SS G
Sbjct: 1966 PYGSGSGWSSSRGP----YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS 2021
Query: 326 KALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNY-EGPLHSLQS 384
+ S H +S S+ GS S S+G + R G + SP + + S QS
Sbjct: 2022 ASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG---YGRQGSGSGQSPGHGQRGSGSRQS 2078
Query: 385 RIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTG 440
R H GP G G G S + + G GSG+ +G
Sbjct: 2079 PSYGRHGSGSGRSSSSGQH--GPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 2132
Score = 47.4 bits (111), Expect = 4e-05
Identities = 90/357 (25%), Positives = 126/357 (35%), Gaps = 45/357 (12%)
Query: 31 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 90
SSG++G S S F S SW + G+ G + Y+ SR
Sbjct: 2327 SSGRHGSGSGQSSGF------GHHESSSWQSSGYTQHGSGSGHSSSYEQHGSR------- 2373
Query: 91 LSPPFVNSRIQSKTER-----GSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKP- 144
S S+ ER GS SSYG+ + +QSL G G+ + SP++
Sbjct: 2374 -------SGQSSRGERHGSSSGSSSSYGQHGSGS---RQSLGHGQHGSGSGQSPSPSRGR 2423
Query: 145 -GSQYYQYSSNNP---------RRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADY 194
GS Q SS +P R P S + R+ G SS Y S++ +
Sbjct: 2424 HGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSG-QSSGYGQHGSSSGH 2482
Query: 195 NRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSY 254
+ + G S S+ G SS S GY G G+ S
Sbjct: 2483 S-STHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGY-GRQGSGSGQSPGHGQ 2540
Query: 255 CSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGA 314
+ SY H S SS S H SG S ++G S + GSG+
Sbjct: 2541 RGSGSRQSPSYGRHGSGSGRSS---SSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS 2597
Query: 315 AGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASS 371
SS G ++ S H ++S SS+ GS S+G GQ+ S
Sbjct: 2598 GHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPS 2654
Score = 45.8 bits (107), Expect = 1e-04
Identities = 108/415 (26%), Positives = 146/415 (35%), Gaps = 57/415 (13%)
Query: 32 SGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMT--SRDLGSHD 89
S GP SGH +G ++ S S G G H S S + + + S G H
Sbjct: 568 SSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHG 627
Query: 90 NLSPPFVNSRIQSKTERGSYSS----YGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPG 145
S + S + GS SS YG++ + G G D G+ + G
Sbjct: 628 ATS-----GQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGS-DFGHSSSYGQHGSG 681
Query: 146 SQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSK 205
S + SSN P H S + K G SS Y+ S + + S GY K
Sbjct: 682 SGW--SSSNGP-----HGSVSGQSSGFGHKSGSG-QSSGYSQHGSGSSH---SSGY--RK 728
Query: 206 PATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSY 265
+ + SS + H SS SSS G + +G +S H Q S S H R+ +
Sbjct: 729 HGSRSGQSS--RSEQHGSSSGLSSSYGQHG---SGSHQSSGHGRQGSG--SGHSPSRVRH 781
Query: 266 PSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAA-GSSQTGDAL 324
S S + T S HY + S G S SG+ G SQ G A
Sbjct: 782 GSSSGHSSSHGQHGSGTSCSSSCGHYESGS------GQASGFGQHESGSGQGYSQHGSAS 835
Query: 325 GKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQS 384
G FSS GS S+ + + GQ+SS +E H
Sbjct: 836 G--------------HFSSQGRH--GSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASG 879
Query: 385 RIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPS-HNGAMGGLGSGYG 438
R H R G S + G HG G S +G+ G SG+G
Sbjct: 880 RGRHGSGSGQSPGHGQRGSGSGQSPSY-GRHGSGSGRSSSSGRHGSGSGQSSGFG 933
Score = 45.8 bits (107), Expect = 1e-04
Identities = 87/357 (24%), Positives = 124/357 (34%), Gaps = 28/357 (7%)
Query: 32 SGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMT--SRDLGSHD 89
S GP SGH +G + S S G G H S S + + + S G H
Sbjct: 1974 SSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQH- 2032
Query: 90 NLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYY 149
S +S Q + S YGR+ + G QS G G+ + S + GS
Sbjct: 2033 GASSGQSSSHGQHGSGSSQSSGYGRQGSGSG---QSPGHGQRGSGSRQSPSYGRHGSGSG 2089
Query: 150 QYSSNNPRRRPL-------HSSAMEVQTKKVRKVPPGL-PSSVYAPSASTADYNRDSPGY 201
+ SS+ L H + Q+ + G SS Y S + + +
Sbjct: 2090 RSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERH 2149
Query: 202 PSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLH-PH 260
SS ++S + G H S SS Q +G + S + S H H
Sbjct: 2150 GSSSGSSSRY--------GQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQH 2201
Query: 261 ERLSYPSHSSADINSSLPPMSTF--HRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSS 318
S S S S S F H SG+ H S S +G GS +G S
Sbjct: 2202 GSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGS-TSGQS 2260
Query: 319 QTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNY 375
T D G + S H + S+ S+ G S S + R+G + S +Y
Sbjct: 2261 STFDQEGSSTGQ--SSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSY 2315
Score = 45.4 bits (106), Expect = 2e-04
Identities = 114/461 (24%), Positives = 160/461 (34%), Gaps = 61/461 (13%)
Query: 31 SSGKNGPTSLASGHFT--GSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSH 88
S G++G TS S F GS+ SS G G+G S S +YG GS
Sbjct: 2249 SQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGS--SQSSSYGQQ-----------GSG 2295
Query: 89 DNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLL---GGDMDMGNPGTLSPTKPG 145
SP SR + + G SSYG+ + G S G G S +
Sbjct: 2296 SGQSP----SRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS 2351
Query: 146 SQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSAST----ADYNRDSPGY 201
S Y Q+ S + HSS+ E + + G + S+S+ +R S G+
Sbjct: 2352 SGYTQHGSGSG-----HSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGH 2406
Query: 202 PSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCS-LHPH 260
+ PS G H S SSS +G + S + S L
Sbjct: 2407 GQHGSGSGQSPSP---SRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHR 2463
Query: 261 ERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQT 320
E S S SS ST + G+ +SSC + ++ G +GSSQ+
Sbjct: 2464 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQ-SSSHGQHGSGSSQS 2522
Query: 321 GDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNG-------------- 366
+ S SP H S S G S S ++ ++G
Sbjct: 2523 SGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHES 2582
Query: 367 --GQASS-SPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIG 423
GQ+SS S + G HS S R + R+ + S++ G HG G
Sbjct: 2583 SSGQSSSYSQHGSGSGHS--SGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGS-----G 2635
Query: 424 PSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGS 464
+ G GSG G S RH +G G GS
Sbjct: 2636 SRQSSGHGRQGSGSGQS-PSRGRHGSGLGHSSSHGQHGSGS 2675
Score = 45.1 bits (105), Expect = 2e-04
Identities = 102/441 (23%), Positives = 147/441 (33%), Gaps = 66/441 (14%)
Query: 47 GSNVEDRSSSGSWGNG-GHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTE 105
GS S G G+G G S S +G G S G H++ S +S Q +
Sbjct: 2072 GSGSRQSPSYGRHGSGSGRSSSSGQHGPGLG----ESSGFGHHESSSGQS-SSYSQHGSG 2126
Query: 106 RGSYSSYGRESNLQGCHQQ-----SLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRP 160
G S YG+ + G + S G G G+ S G S + R
Sbjct: 2127 SGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRG 2186
Query: 161 LHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFP-----SSF 215
H S + + SS P S + ++ + S +S + S
Sbjct: 2187 RHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 2246
Query: 216 FMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINS 275
F G H S SS+ +Q G S QSSS+ H S+ S
Sbjct: 2247 FCSQGQHGSTSGQSST-FDQEG--------SSTGQSSSH-GQHGSGSSQSSSYGQQGSGS 2296
Query: 276 SLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPD 335
P H SG+ H S+ +G S GSG+ SS G +S S
Sbjct: 2297 GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGH---HESSSWQSSG 2353
Query: 336 HTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDD 395
+T + S S+ S S ++ R+G + SS +Y
Sbjct: 2354 YTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSY-------------------- 2393
Query: 396 AIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSG---------YGTGL-LSAN 445
H G ++ GHG G S + + G GSG YG+G S++
Sbjct: 2394 -----GQHGSGSRQSL--GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSS 2446
Query: 446 RHSLMVGTHREDGVALRGSHS 466
R G+ G+ R S S
Sbjct: 2447 RGPYESGSGHSSGLGHRESRS 2467
Score = 44.7 bits (104), Expect = 3e-04
Identities = 99/431 (22%), Positives = 141/431 (32%), Gaps = 46/431 (10%)
Query: 47 GSNVEDRSSSGSWGNG-GHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTE 105
GS S G G+G G S S +G G S G H++ S +S Q +
Sbjct: 1602 GSGSRQSPSYGRHGSGSGRSSSSGQHGSGLG----ESSGFGHHESSSGQS-SSYSQHGSG 1656
Query: 106 RGSYSSYGRESNLQGCHQQSLLGGDMDM-----GNPGTLSPTKPGSQYYQYSSNNPRRRP 160
G S YG+ + G + G G G+ S G S R
Sbjct: 1657 SGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRG 1716
Query: 161 LHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFP-----SSF 215
H S + + + SS P S + ++ + S +S + S
Sbjct: 1717 RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 1776
Query: 216 FMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINS 275
F G H S SS+ +Q G S QSSS+ H S+ S
Sbjct: 1777 FCSQGQHGSTSGQSST-FDQEG--------SSTGQSSSH-GQHGSGSSQSSSYGQQGSGS 1826
Query: 276 SLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPD 335
P H SG+ H S+ +G S GSG+ SS G
Sbjct: 1827 GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFG-------------H 1873
Query: 336 HTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDD 395
H ++S+ S+ T GS S+ GQ+S + S S +
Sbjct: 1874 HESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQS 1933
Query: 396 AIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHR 455
H G S + G HG G + + G GSG G S++R G+
Sbjct: 1934 LGHGQHGSGSGQSPSPSRGR---HG-SGSGQSSSYGPYGSGSG---WSSSRGPYESGSGH 1986
Query: 456 EDGVALRGSHS 466
G+ R S S
Sbjct: 1987 SSGLGHRESRS 1997
Score = 43.9 bits (102), Expect = 5e-04
Identities = 101/408 (24%), Positives = 138/408 (33%), Gaps = 57/408 (13%)
Query: 41 ASGHFTGSNVEDRSSSGSWGNGGHPSPS---RNYGDGTPYDHMTSRD--LGSHDNLSPPF 95
ASGHF+ +S S +G H S S +YG H S GS SP
Sbjct: 834 ASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSP-- 891
Query: 96 VNSRIQSKTERGSYSSYGRESNLQGCHQQSLL--GGDMDMGNPGTLSPTKPGSQYYQYSS 153
Q + G SYGR + G S G G S + S Y Q+ S
Sbjct: 892 --GHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGS 949
Query: 154 NNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPS 213
+ HSS+ E R + S S++ Y + G S
Sbjct: 950 GSG-----HSSSYEQHGS--RSGQSSRSEQHGSSSGSSSSYGQHGSGSRQS--------- 993
Query: 214 SFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADI 273
+ G H S SG + G G+ S QSSSY P S +
Sbjct: 994 ---LGHGQHGS-----GSGQSPSPSRGRHGSGSG--QSSSYG----------PYRSGSGW 1033
Query: 274 NSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYS 333
+SS P + SG+ H S +G S GS + SS G + S
Sbjct: 1034 SSSRGP----YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 1089
Query: 334 PDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNY-EGPLHSLQSRIEDRLER 392
H +S S+ GS S S+G + R G + SP + + S QS R
Sbjct: 1090 GQHGASSGQSSSHGQHGSGSSQSSG---YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 1146
Query: 393 LDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTG 440
H G + GH + G S + + G GSG+ +G
Sbjct: 1147 GSGRSSSSGQHGSGLGESSGFGHHESSS--GQSSSYSQHGSGSGHSSG 1192
Score = 43.9 bits (102), Expect = 5e-04
Identities = 113/455 (24%), Positives = 154/455 (33%), Gaps = 49/455 (10%)
Query: 31 SSGKNGPTSLASGHFT--GSNVEDRSSSGSWGNGGHPSPSRNYG-DGTPYDHMTSRDLGS 87
S G++G TS S F GS+ SS G G+G S S YG G SR G
Sbjct: 1309 SQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGS--SQSSGYGRHGAGSGQSPSR--GR 1364
Query: 88 HDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQ 147
H + S S + GS S + S G S G G+ + S G
Sbjct: 1365 HGSGS-----GHSSSYGQHGSGSGWSSSSGRHG----SGSGQSSGFGHHESSSWQSSGCT 1415
Query: 148 YYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPA 207
+ S + H S ++ R SS Y S + R S G+
Sbjct: 1416 QHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGS---RQSLGHGQHGSG 1472
Query: 208 TSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCS-LHPHERLSYP 266
+ PS G H S SSS +G + SS+ S L E S
Sbjct: 1473 SGQSPSP---SRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQ 1529
Query: 267 SHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGK 326
S SS ST + G+ +SSC + ++ G +GSSQ+ +
Sbjct: 1530 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQ-SSSHGQHGSGSSQSSGYGRQ 1588
Query: 327 ALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNG----------------GQAS 370
S SP H S S G S S ++ ++G GQ+S
Sbjct: 1589 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSS 1648
Query: 371 S-SPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGA 429
S S + G HS S R + R+ + S++ G HG G +
Sbjct: 1649 SYSQHGSGSGHS--SGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGS-----GSRQSSG 1701
Query: 430 MGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGS 464
G GSG G S RH +G G GS
Sbjct: 1702 HGRQGSGSGQS-PSRGRHGSGLGHSSSHGQHGSGS 1735
Score = 42.7 bits (99), Expect = 0.001
Identities = 106/464 (22%), Positives = 162/464 (34%), Gaps = 40/464 (8%)
Query: 31 SSGKNGPTSLAS-GHFT-GSNVEDRSSSGSWGNG-GHPSPSRNYGDGTPYDHMTSRDLGS 87
S G++G S S GH GS S G+G GH S +G G+ Y + SR
Sbjct: 282 SYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSY--SRGHYE 339
Query: 88 HDNLSPPFVNSRIQSKTERGSYSSYGR---ESNLQGCHQQSLLGGDMDMGNPGTLSPTKP 144
+ + YS +G S+ QG H S G G G+ S
Sbjct: 340 SGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHG-STSGQASSSGQHGSSSRQSS 398
Query: 145 GSQYYQYSSNNPRRRPLHSSAM-------EVQTKKVRKVPPGLPSSVYAPSASTADYNRD 197
++ +S + R HSS + + + G + + S+S+ Y
Sbjct: 399 SYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSG 458
Query: 198 SPGYPSS--KPATSTFPSSFFMQDGH---HSSDPWSSSSGMNQPGYAGMLGNSSHIPQSS 252
S GY S +S+ SS + Q G HSS S Q G+S+ S
Sbjct: 459 S-GYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSY 517
Query: 253 SYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGS 312
+ L + H S S P H SG+ S+ +G S S
Sbjct: 518 GQHGSGSRQSLGHSRHGSGSGQSPSPSRGR-HESGSRQSSSYGPHGYGSGRSSSRGPYES 576
Query: 313 GAAGS-------SQTGDALG---KALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVW 362
G+ S S++G + G +S +S H + +S S+ G + S ++
Sbjct: 577 GSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSH 636
Query: 363 SRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGII 422
++G +S S Y G S + R D H G + +G HG +
Sbjct: 637 GQHGSGSSQSSRY-GQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGP-HGSV 694
Query: 423 GPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHS 466
+G GSG +G ++H G+ G GS S
Sbjct: 695 SGQSSGFGHKSGSGQSSGY---SQHG--SGSSHSSGYRKHGSRS 733
Score = 41.6 bits (96), Expect = 0.002
Identities = 94/382 (24%), Positives = 139/382 (36%), Gaps = 48/382 (12%)
Query: 23 SAMFSPPVS----SGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYD 78
S+ +SP S S GP SGH +G + S S G G H S S + +
Sbjct: 2431 SSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG 2490
Query: 79 HMT--SRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNP 136
+ S G H S +S Q + S YGR+ + G QS G G+
Sbjct: 2491 STSGQSSSCGQH-GASSGQSSSHGQHGSGSSQSSGYGRQGSGSG---QSPGHGQRGSGSR 2546
Query: 137 GTLSPTKPGSQYYQYSSNNPRRRPL-------HSSAMEVQTKKVRKVPPGLP-SSVYAPS 188
+ S + GS + SS+ L H + Q+ + G SS Y
Sbjct: 2547 QSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH 2606
Query: 189 ASTADYNRDSPGYPSSKPATSTFPS--SFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSS 246
S + + + SS ++S + S Q H S ++ + LG+SS
Sbjct: 2607 GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSS 2666
Query: 247 ----HIPQSSSYCSLHPHE-RLSYPS----HSSADINSSLPPMSTFHRSGTNHY------ 291
H S S P+E RL + S H S +SS H SG+ H+
Sbjct: 2667 SHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQ---HGSGSGHFCSQGQH 2723
Query: 292 -------STSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSN 344
ST + G S +RGSG++ SS G S S H + S
Sbjct: 2724 GSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYG---RHGAGSGQSLSHGRHGSGSG 2780
Query: 345 PSTPVGSPPSLSAGTAVWSRNG 366
S+ G S S ++ +S++G
Sbjct: 2781 QSSSYGQHGSGSGQSSGYSQHG 2802
Score = 41.2 bits (95), Expect = 0.003
Identities = 60/235 (25%), Positives = 86/235 (36%), Gaps = 19/235 (8%)
Query: 145 GSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTAD-YNRDSPGYPS 203
G Y Q S + R + +T+K S + SA D Y+R+ G S
Sbjct: 90 GKDYCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRG--S 147
Query: 204 SKPATSTFPSSFFMQ---DGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPH 260
KP T + Q G H+S SSS G + SH C
Sbjct: 148 LKPGTESISRRLSFQRDFSGQHNSYSGQSSS-------YGEQNSDSHQSSGRGQCGSGSG 200
Query: 261 ERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQT 320
+ +Y H S SS + H SG+ S S ++G S + GSG+ SS
Sbjct: 201 QSPNYGQHGSGSGQSS---SNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGY 257
Query: 321 GDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNY 375
G ++ S H ++S SS+ GS S G R G + SP++
Sbjct: 258 GQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLG---HGRQGSGSRQSPSH 309
Score = 40.0 bits (92), Expect = 0.007
Identities = 83/325 (25%), Positives = 116/325 (35%), Gaps = 31/325 (9%)
Query: 51 EDRSSSGSWGNGGHPSPSRNY-GDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSY 109
E S SW G + S SRN G P SR L + S Q + G
Sbjct: 124 ESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSG-------QHNSYSGQS 176
Query: 110 SSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPT--KPGSQYYQYSSNNPRRRPLHSSAME 167
SSYG +++ HQ S G G+ SP + GS Q SSN+ H S
Sbjct: 177 SSYGEQNS--DSHQSS---GRGQCGSGSGQSPNYGQHGSGSGQSSSNDT-----HGSGSG 226
Query: 168 VQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPW 227
+ + SS Y+ S + ++ G S+ S+ + H SS
Sbjct: 227 QSSGFSQHKSSSGQSSGYSQHGSGSGHS-SGYGQHGSRSGQSS------RGERHRSSSGS 279
Query: 228 SSSSGMNQPGYAGMLGNS---SHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFH 284
SSS G + G LG+ S QS S+ H SH SS +
Sbjct: 280 SSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVR-HGSGSGHSSSHGQHGSGSSYSYSRGHY 338
Query: 285 RSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSN 344
SG+ S +G S + GSG+ SS G + + S H ++S S+
Sbjct: 339 ESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSS 398
Query: 345 PSTPVGSPPSLSAGTAVWSRNGGQA 369
S S+G S GQ+
Sbjct: 399 SYGQHESASRHSSGRGQHSSGSGQS 423
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 48.9 bits (115), Expect = 2e-05
Identities = 95/441 (21%), Positives = 149/441 (33%), Gaps = 79/441 (17%)
Query: 31 SSGKNGPTSLASGHFTGSNVEDRSSSGSWG--NGGHPSPSRNYGDG-TPYDHMTSRDLGS 87
SSG S GH S+ + S G G H +R+ G + + +
Sbjct: 3335 SSGSQASDS--EGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVST 3392
Query: 88 HDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQ 147
H+ +R + +GS+ R+S+ Q+ G D G+PG+ + GS
Sbjct: 3393 HEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQE---GQDTIRGHPGSSRRGRQGSH 3449
Query: 148 YYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPS-------------------SVYAPS 188
Y Q + HS + G S S + +
Sbjct: 3450 YEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEA 3509
Query: 189 ASTADYNRDSPG--YPSSKPATSTFPSSFFMQD----GH-HSSDPWSSSSGMNQPGYAGM 241
++ AD +R S S+ P TS S QD GH S+ WS S+ N G A
Sbjct: 3510 STQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSA-- 3567
Query: 242 LGNSSHIPQSSSYCSLHP---HERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTP 298
+ S S HP HE + HS+ + +SGT+H SS
Sbjct: 3568 -------QEQSRDGSRHPTSHHEDRAGHGHSA----------ESSRQSGTHHAENSSGGQ 3610
Query: 299 PANGTDSIMANRG--------SGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVG 350
A+ + ++ G A S +G G+A +++ H +S S +
Sbjct: 3611 AASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGH 3670
Query: 351 SPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTA 410
S S + + + G P+ + S + R R R ++ + H S
Sbjct: 3671 SEDSDTQSVSAHGQAG------PHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESA- 3723
Query: 411 MPGGHGDMHGIIGPSHNGAMG 431
HG GPS G G
Sbjct: 3724 --------HGRAGPSTGGRQG 3736
Score = 46.6 bits (109), Expect = 7e-05
Identities = 97/438 (22%), Positives = 157/438 (35%), Gaps = 84/438 (19%)
Query: 31 SSGKNGPTSLASGHFTGSNVEDRSSSGSWG--NGGHPSPSRNY-GDGTPYDHMTSRDLGS 87
SSG S GH S+ + S G G H +R G+ + + + +
Sbjct: 417 SSGSQASDS--EGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVST 474
Query: 88 HDNLSPPFVNSRIQSKT--ERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPG 145
H+ P + R + T +GS+ R+S+ Q+ G D G+PG+ + G
Sbjct: 475 HEQ--PDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQE---GQDTIRGHPGSSRGGRQG 529
Query: 146 SQYYQ-------------YSSNNPRRRPLH----SSAMEVQTKKVRKVPPGL--PSSVYA 186
S + Q ++++ R H S + QT+ + G S +
Sbjct: 530 SHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHH 589
Query: 187 PSASTADYNRDSP--GYPSSKPATSTFPSSFFMQD----GH-HSSDPWSSSSGMNQPGYA 239
++S AD +R S SS P TS S QD GH S+ WS S+ N G A
Sbjct: 590 EASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSA 649
Query: 240 GMLGNSSHIPQSSSYCSLHP---HERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSC 296
+ S S HP HE + HS+ + +SGT H SS
Sbjct: 650 ---------QEQSRDGSRHPRSHHEDRAGHGHSA----------DSSRKSGTRHTQNSSS 690
Query: 297 TPPANGTDSIMANRG---------SGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPST 347
A+ + ++ G A S +G G+A +++ H +S S +
Sbjct: 691 GQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDS 750
Query: 348 PVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGP 407
S S + + G + + + S + R +R R ++ + H
Sbjct: 751 EGHSEDSDTQSVS------GHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSE 804
Query: 408 STAMPGGHGDMHGIIGPS 425
S+ HG GPS
Sbjct: 805 SS---------HGWTGPS 813
Score = 46.6 bits (109), Expect = 7e-05
Identities = 127/588 (21%), Positives = 193/588 (32%), Gaps = 108/588 (18%)
Query: 2 HHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPT----SLASGHFTGSNVEDRSSSG 57
HHQQ D + S SG G + S + GH S+ + S+ G
Sbjct: 2333 HHQQ-----SADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHG 2387
Query: 58 SWG--NGGHPSPSRNYGDG-TPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGR 114
G H +R G + + +H+ + + +GS+ R
Sbjct: 2388 QAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQAR 2447
Query: 115 ESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHS----------- 163
+S+ H S G D G+PG+ S + GS Y Q + HS
Sbjct: 2448 DSSR---HSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDAS 2504
Query: 164 ---SAMEVQTKKVRKVPPGLPSSVYAPSA-STADYNRDSPGY------PSSKPATSTFPS 213
S +++ R S ++ S A DS G+ S P TS
Sbjct: 2505 HGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWG 2564
Query: 214 SFFMQD----GH-HSSDPWSSSSGMNQPGYA-GMLGNSSHIPQSSSYCSLHPHERLSYPS 267
S F QD GH S+ WS S+ N G A L + S P+S H +R +
Sbjct: 2565 SSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRS------HQEDRAGH-G 2617
Query: 268 HSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKA 327
HS+ + +SGT H TSS G A+ Q + G+
Sbjct: 2618 HSA----------DSSRQSGTRHTQTSS--------------GGQAASSHEQARSSAGER 2653
Query: 328 LASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIE 387
S H S S+ + +G GQASS+ G S+
Sbjct: 2654 HGS-----HHQQSADSSRHSGIGH---------------GQASSAVRDSGHRGYSGSQAS 2693
Query: 388 DRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRH 447
D +D+ + + G H H S G G G+ L + H
Sbjct: 2694 DNEGHSEDS-----DTQSVSAHGQAGSHQQSH---QESARGRSGETSGHSGSFLYQVSTH 2745
Query: 448 SLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVS 507
+H G + RG Q Q + + S D QD RG P +G
Sbjct: 2746 EQSESSHGWTGPSTRGRQGSRHEQA---QDSSRHSASQD---GQDTIRGHPGSSRG-GRQ 2798
Query: 508 SGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDE 555
E D G + ++ + D + S + SR++ N+++
Sbjct: 2799 GYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQ 2846
Score = 43.9 bits (102), Expect = 5e-04
Identities = 102/474 (21%), Positives = 153/474 (32%), Gaps = 90/474 (18%)
Query: 5 QRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWG--NG 62
Q+ A TD D S + S + GH S+ + S+ G G
Sbjct: 1686 QQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQ 1745
Query: 63 GHPSPSRNYGDGTP-------YDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRE 115
H +R Y T S + P R +S+ E+ SS
Sbjct: 1746 SHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSR--- 1802
Query: 116 SNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRK 175
H S G D G+PG+ + GS Y Q ++ HS + V +
Sbjct: 1803 ------HSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSR 1856
Query: 176 VPPGLPS-------------------SVYAPSASTADYNRDSP--GYPSSKPATSTFPSS 214
G S S + ++S AD +R S SS P TS S
Sbjct: 1857 GQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGS 1916
Query: 215 FFMQD----GH-HSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHP---HERLSYP 266
QD GH S+ WS S+ N G A + S S HP HE +
Sbjct: 1917 SVSQDSDSQGHSEDSERWSGSASRNHLGSAW---------EQSRDGSRHPGSHHEDRAGH 1967
Query: 267 SHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRG---------SGAAGS 317
HS+ + +SGT H +SS A+ + ++ G A S
Sbjct: 1968 GHSA----------DSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSS 2017
Query: 318 SQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEG 377
+G G+A +++ H S S + S S + + Q + P+ +
Sbjct: 2018 RHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVS------AQGKAGPHQQS 2071
Query: 378 PLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMG 431
S + + + R ++ + H ST HG PS G G
Sbjct: 2072 HKESARGQSGESSGRSGSFLYQVSTHEQSEST---------HGQSAPSTGGRQG 2116
Score = 43.1 bits (100), Expect = 8e-04
Identities = 114/567 (20%), Positives = 177/567 (31%), Gaps = 65/567 (11%)
Query: 2 HHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWG- 60
HHQ + A + SA+ S + GH S+ + S+ G G
Sbjct: 2008 HHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGP 2067
Query: 61 -NGGHPSPSRNY-GDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNL 118
H +R G+ + + +H+ S + +GS+ ++S+
Sbjct: 2068 HQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSR 2127
Query: 119 QGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPP 178
Q+ G D G+PG + GS Q + HS +
Sbjct: 2128 HSASQE---GQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQS 2184
Query: 179 GLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGY 238
G + SAS Y+++ G S + HH + W+ SS + G
Sbjct: 2185 G------SRSASRKTYDKEQSGDGSRHSGSH-----------HHEASSWADSSRHSLVGQ 2227
Query: 239 AGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTP 298
G + P+ SS E HS S H S S P
Sbjct: 2228 GQSSGPRTSRPRGSSVSQDSDSE-----GHSEDSERRSGSASRNHHGSAQEQSRDGSRHP 2282
Query: 299 PANGTDSIMANRGSGAAGSSQTG-----DALGKALASIYSPDHTNNSFSSNPSTPVGSPP 353
++ D A G A S Q+G ++ G AS ++ S+ GS
Sbjct: 2283 RSHHED--RAGHGHSAESSRQSGTHHAENSSGGQAAS------SHEQARSSAGERHGSHH 2334
Query: 354 SLSAGTAVWSRNG-GQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMP 412
SA ++ S G GQASS+ G S S+ D H+ T
Sbjct: 2335 QQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDS-----------EGHSEDSDTQSV 2383
Query: 413 GGHGDMHGIIGPSHNGAMGGLGSG----YGTGLLSANRHSLMVGTHREDGVALRGSHSLL 468
HG G SH + G +G G+ L + H H G + G
Sbjct: 2384 SAHGQA-GPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSH 2442
Query: 469 PNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKS 528
Q S+ QD G P G S ++ D G + +
Sbjct: 2443 HKQAR------DSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQL-VDRSGHSGSHHSHT 2495
Query: 529 SEDKKLDDDKKDIKSITRSRSSNNDDE 555
+ + D S + SR + ND++
Sbjct: 2496 TSQGRSDASHGHSGSRSASRQTRNDEQ 2522
Score = 38.1 bits (87), Expect = 0.027
Identities = 111/538 (20%), Positives = 172/538 (31%), Gaps = 67/538 (12%)
Query: 31 SSGKNGPTSLASGHFTGSNVEDRSSSGSWG--NGGHPSPSRNYGDG-TPYDHMTSRDLGS 87
SSG S GH S+ + S G G H +R++ G + + +
Sbjct: 1066 SSGSQASDS--EGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVST 1123
Query: 88 HDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQ 147
H+ +R + +GS+ R+S+ Q+ G D +PG+ + GS
Sbjct: 1124 HEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQE---GQDTIRAHPGSRRGGRQGSH 1180
Query: 148 YYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPA 207
+ Q + HS T + R S + S T +D S+ +
Sbjct: 1181 HEQSVDRSGHSGSHHSHT----TSQGRSDASHGQSGSRSASRQT---RKDKQSGDGSRHS 1233
Query: 208 TSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPS 267
S HH + W+ SS +Q G G+ + Q SS ER
Sbjct: 1234 GSR----------HHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSER----- 1278
Query: 268 HSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTG------ 321
HS S H S S P + D A+ G A S Q+G
Sbjct: 1279 HSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQED--RASHGHSADSSRQSGTHHTES 1336
Query: 322 DALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNG-GQASSSPNYEGPLH 380
+ G+A++S + S+P GS SA ++ S G QASS+ G
Sbjct: 1337 SSHGQAVSS-------HEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRG 1389
Query: 381 SLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTG 440
S S++ + H+ T HG A G G G
Sbjct: 1390 SSGSQVTNS-----------EGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRS 1438
Query: 441 ---LLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGM 497
L + H TH + + G Q S+ QD RG
Sbjct: 1439 RSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQAR------NSSRHSASQDGQDTIRGH 1492
Query: 498 PPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDE 555
P +G S E D G + ++ + D + SR + N+++
Sbjct: 1493 PGSSRGGRQGS-YHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQ 1549
Score = 37.4 bits (85), Expect = 0.045
Identities = 72/359 (20%), Positives = 124/359 (34%), Gaps = 26/359 (7%)
Query: 32 SGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHP----SPSRNYGDGTPYDHMTSRDLGS 87
SG + +SG S+ + RSS+G H SR+ G G RD G
Sbjct: 680 SGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGH 739
Query: 88 HDNLSPPFVNSRIQSK-TERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGS 146
+ +S S+ ++ S S +G+ + Q HQ+S + + GS
Sbjct: 740 RGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSR-------RSGS 792
Query: 147 QYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKP 206
YQ S++ + ++ +S ++ S D R PG S +
Sbjct: 793 FLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPG-SSRRG 851
Query: 207 ATSTFPSSFFMQDGH------HSSDPWSSSSGMNQPGYAGMLGNSSHIPQS---SSYCSL 257
+ + GH H++ S + Q G + + QS S +
Sbjct: 852 RQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGS 911
Query: 258 HPHERLSYPS---HSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGA 314
HE S+ HS A S T R G++ S + ++ +
Sbjct: 912 RHHEASSHADISRHSQAGQGQS-EGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNH 970
Query: 315 AGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSP 373
GS+Q G + D + S++ S G+P + ++ + + QA SSP
Sbjct: 971 RGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSP 1029
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 47.8 bits (112), Expect = 3e-05
Identities = 106/444 (23%), Positives = 156/444 (35%), Gaps = 60/444 (13%)
Query: 36 GPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSR--NYGDGTPYDHMTSRDLGSHDNLSP 93
G SG +G + S S G G H S S NYG +S G H + S
Sbjct: 962 GQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSS-GYGQHGSSSG 1020
Query: 94 PFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSS 153
Q ++ G YS +G+ + G Q S G GT S G Y+ S
Sbjct: 1021 QTTGFG-QHRSSSGQYSGFGQHGS--GSDQSS------GFGQHGTGSGQSSGFGQYESRS 1071
Query: 154 NNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPS 213
S + + SS Y S + + G+ +P + S
Sbjct: 1072 RQSSYGQHGSGSSQ--------------SSGYGQHGSNSG---QTSGFGQHRPGSGQ--S 1112
Query: 214 SFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQS---SSYCSLHPHERLSYPSHSS 270
S F Q G S SSG Q G G SS Q S S H S S
Sbjct: 1113 SGFGQYGSGSGQ----SSGFGQHGSG--TGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGC 1166
Query: 271 ADINSSLPPMSTF--HRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKAL 328
S P ++F H SG++++S+S +G + GSG+ S+ G + +
Sbjct: 1167 GQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQV 1226
Query: 329 AS---IYSPDHTNNSFSSNPS--TPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQ 383
S ++ T + + N + + G S G+ V R ++S S N + +HS
Sbjct: 1227 ESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRR--RSSQSENSDSEVHSKV 1284
Query: 384 SRIEDRLERLDDAIHV-LRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLL 442
S R + IH +H + + G HG G + G G TG
Sbjct: 1285 S------HRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSR 1338
Query: 443 SANR----HSLMVGTHREDGVALR 462
++ R HS + GV+ R
Sbjct: 1339 TSGRQRFSHSDATDSEVHSGVSHR 1362
Score = 42.0 bits (97), Expect = 0.002
Identities = 92/414 (22%), Positives = 140/414 (33%), Gaps = 55/414 (13%)
Query: 33 GKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPS----RNYGDGTPYDHMTSRDLGSH 88
G+ G TS S G + + SS+ GH S + G T H S+ H
Sbjct: 1849 GQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQARSQH 1908
Query: 89 DNLSPPFVNSRIQSKT-ERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQ 147
S V+ R Q+ + G + +G S H Q++ G G + GS
Sbjct: 1909 GE-SESTVHKRHQTTHGQTGDTTEHGHPS-----HGQTIQTGSRTTG--------RRGSG 1954
Query: 148 YYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPA 207
+ +YS + H+ + + P SSV+ +T D+ + S
Sbjct: 1955 HSEYSDSEGPSGVSHTHSGHTHGQAGSHYPES-GSSVHERHGTTHGQTADTTRHGHSGHG 2013
Query: 208 TSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPS 267
ST Q G S ++G G++ + H S H H S +
Sbjct: 2014 QST-------QRG-------SRTTGRRASGHSEYSDSEGHSGVS------HTH---SGHA 2050
Query: 268 HSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTG--DALG 325
H A S R GT H T T A+ RGS AG +G ++
Sbjct: 2051 HGQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSD 2110
Query: 326 KALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNG---GQASSSPNYEGPLHSL 382
+ S S H+ +++ S S G+A+ R G GQ + + H
Sbjct: 2111 SEVHSGVSHTHSGHTYGQARSQHGES------GSAIHGRQGTIHGQTGDTTRHGQSGHGQ 2164
Query: 383 QSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSG 436
++ R + H + + S A P G H G H G G G G
Sbjct: 2165 STQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRH-GQSGSSGHG 2217
Score = 34.3 bits (77), Expect = 0.38
Identities = 98/437 (22%), Positives = 141/437 (32%), Gaps = 33/437 (7%)
Query: 32 SGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDNL 91
SG++ +SG S S + G G H S S Y + + G ++
Sbjct: 613 SGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHV 672
Query: 92 SPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQY 151
S +S R +SSYG+ G Q S G G+ S G ++
Sbjct: 673 SGSGQSSGFGQHESRSGHSSYGQHGF--GSSQSS------GYGQHGSSSGQTSGFGQHEL 724
Query: 152 SSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTA---DYNRDSPGYPSSKP-- 206
SS H S + + SS + S + Y + S G S
Sbjct: 725 SSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYG 784
Query: 207 ATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHE----R 262
+ +S F Q G SS S+ G G G H S HE +
Sbjct: 785 QHGSRQTSGFGQHGSGSSQ--STGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQ 842
Query: 263 LSYPSHSSADINSS--------LPPMSTF--HRSGTNHYSTSSCTPPANGTDSIMANRGS 312
SY H S SS S F HRS + YS +G S G+
Sbjct: 843 SSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGT 902
Query: 313 GAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSS 372
G+ S G ++ S Y H + S S+ GS + G GQ+S
Sbjct: 903 GSGQYSGFGQHESRSHQSSYG-QHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGF 961
Query: 373 PNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGD-MHGIIGPSHNGAMG 431
+ S QS + E H S + G HG G +G+
Sbjct: 962 GQHGS--GSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSS 1019
Query: 432 GLGSGYGTGLLSANRHS 448
G +G+G S+ ++S
Sbjct: 1020 GQTTGFGQHRSSSGQYS 1036
Score = 33.5 bits (75), Expect = 0.65
Identities = 78/347 (22%), Positives = 111/347 (31%), Gaps = 43/347 (12%)
Query: 36 GPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRN-----YGDGTPYDHMTSRDLGSHDN 90
G SG G S S G G H S S +G G+ S G H +
Sbjct: 808 GQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQ----SSGYGQHGS 863
Query: 91 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 150
S + Q ++ G YS +G+ + G Q S G + G+ Q
Sbjct: 864 SSGQ-TSGFGQHRSSSGQYSGFGQHGS--GSGQSSGFG--------------QHGTGSGQ 906
Query: 151 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 210
YS H S+ + SS Y S++ + S +S
Sbjct: 907 YSGFGQHESRSHQSSYGQHGSGSSQ------SSGYGQHGSSSGQTFGFGQHRSGSGQSSG 960
Query: 211 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSS 270
F H S SS G ++ G G H +SS + H S S
Sbjct: 961 FGQ-------HGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQ-SNYGQHGSGSSQSSGY 1012
Query: 271 ADINSSLPPMSTF--HRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKAL 328
SS + F HRS + YS + S G+G+ SS G ++
Sbjct: 1013 GQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSR 1072
Query: 329 ASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNY 375
S Y H + S S+ GS ++G GQ+S Y
Sbjct: 1073 QSSYG-QHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQY 1118
Score = 33.5 bits (75), Expect = 0.65
Identities = 62/269 (23%), Positives = 98/269 (36%), Gaps = 51/269 (18%)
Query: 210 TFPSSFFMQDGH-HSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSH 268
T +S Q GH S+ SS++G + G++ + H S ++ S H H + + H
Sbjct: 1851 TGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGGSHTH-SGHTHSQ-ARSQH 1908
Query: 269 SSADINSSLPPMSTFH-RSGTNHYSTSSCTP---PANGTDSIMANRGSGAAGS--SQTGD 322
++ ST H R T H T T P++G +R +G GS S+ D
Sbjct: 1909 GESE--------STVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSD 1960
Query: 323 ALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNG---GQASSSPNYEGPL 379
+ G + S HT+ S+ +G++V R+G GQ + + +
Sbjct: 1961 SEGPSGVSHTHSGHTHGQAGSHYP---------ESGSSVHERHGTTHGQTADTTRHGHSG 2011
Query: 380 HSLQSRIEDRL--------------ERLDDAIHVLRNHAVGPSTAMPGG--------HGD 417
H ++ R E H HA G + + G HG
Sbjct: 2012 HGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHERHGT 2071
Query: 418 MHGIIGPSHNGAMGGLGSGYGTGLLSANR 446
HG G + A G G G +A R
Sbjct: 2072 THGQTGDTTRHAHSGHGQSTQRGSRTAGR 2100
Score = 30.4 bits (67), Expect = 5.5
Identities = 57/299 (19%), Positives = 88/299 (29%), Gaps = 13/299 (4%)
Query: 31 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 90
S G +G + SGH G SGS + H + D T + H G
Sbjct: 1961 SEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSGH---GQSTQ 2017
Query: 91 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 150
R +E + S+ H G G G+ + G+ + Q
Sbjct: 2018 RGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQH--GESGSSVHERHGTTHGQ 2075
Query: 151 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 210
H + + ++ + G S + S + Y ++
Sbjct: 2076 TGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGE 2135
Query: 211 FPSSFFMQDGH-HSSDPWSSSSGMNQPGYAGMLGN-------SSHIPQSSSYCSLHPHER 262
S+ + G H ++ G + G + G+ SSH S S
Sbjct: 2136 SGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPT 2195
Query: 263 LSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTG 321
S +HS A S R GT H T T A+ RGS G +G
Sbjct: 2196 HSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSG 2254
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 46.6 bits (109), Expect = 7e-05
Identities = 63/253 (24%), Positives = 86/253 (33%), Gaps = 40/253 (15%)
Query: 74 GTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDM 133
G P H GS + +S S + S S + S +G L
Sbjct: 1075 GKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSS 1134
Query: 134 GNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTAD 193
S +K SQ S P P+ + + + P G PSS+ PS S +
Sbjct: 1135 QGSSGSSQSKNSSQ----SGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPN 1190
Query: 194 YN-----------------RDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQP 236
+ + PG P S A S S G H S SSSSGM
Sbjct: 1191 ISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSG---SGGSHMSGT-SSSSGMKSS 1246
Query: 237 GYAGMLGN-SSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSS 295
G G+ S P SS+ C+ SS+ +SS MS+ S H S+
Sbjct: 1247 SGLGSSGSLSQKTPPSSNSCTA-----------SSSSFSSSGSSMSS---SQNQHGSSKG 1292
Query: 296 CTPPANGTDSIMA 308
+P N S+ A
Sbjct: 1293 KSPSRNKKPSLTA 1305
Score = 37.0 bits (84), Expect = 0.059
Identities = 64/260 (24%), Positives = 97/260 (37%), Gaps = 29/260 (11%)
Query: 187 PSASTADYNRDSPGYPSSK----PATSTFPSSFFMQDGHHSSDPWSSSSGMNQ-----PG 237
P AD SP + SS P TST S G + P ++ + + P
Sbjct: 1010 PKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPK 1069
Query: 238 YAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCT 297
M+G S Q +S S+ S+ SHSS+ +S+ SG S S +
Sbjct: 1070 GTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSA-------STSGKMKSSKSEGS 1122
Query: 298 PPANGTDSIMANRGS-GAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLS 356
+ + S+ +++GS G++ S + + GK +S + ++ SS P G P SL
Sbjct: 1123 SSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLM 1182
Query: 357 AGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHG 416
+ S PN P HS D+L + + S G G
Sbjct: 1183 ----------NPSLSKPNI-SPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGG 1231
Query: 417 D-MHGIIGPSHNGAMGGLGS 435
M G S + GLGS
Sbjct: 1232 SHMSGTSSSSGMKSSSGLGS 1251
>gi|121114306 neurogenic differentiation 1 [Homo sapiens]
Length = 356
Score = 46.2 bits (108), Expect = 1e-04
Identities = 38/148 (25%), Positives = 70/148 (47%), Gaps = 15/148 (10%)
Query: 492 DPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLD--DDKKDIKSITRSRS 549
+P PP + +SS E ++D + D+ L+ + ED + +++ + + +
Sbjct: 13 EPQPQGPPSWTDECLSSQDEEHEADKKEDD-LEAMNAEEDSLRNGGEEEDEDEDLEEEEE 71
Query: 550 SNNDDEDLTPEQKA-----------EREKERRMANNARERLRVRDINEAFKELGRMVQLH 598
+D+D P+++ ER K RRM NARER R+ +N A L ++V +
Sbjct: 72 EEEEDDDQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCY 131
Query: 599 LKSDKPQTKLLILHQAVAVILSLEQQVR 626
K+ K +K+ L A I +L + +R
Sbjct: 132 SKTQK-LSKIETLRLAKNYIWALSEILR 158
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 46.2 bits (108), Expect = 1e-04
Identities = 130/557 (23%), Positives = 201/557 (36%), Gaps = 77/557 (13%)
Query: 29 PVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSP-------SRNYGDGTPYDHMT 81
PV+S P+S ++GH T +V D SS+ + GH +P S + GD TP +T
Sbjct: 2290 PVTS----PSSASTGHATPLHVTDASSAST----GHATPLPVTSLSSASTGDTTPLP-VT 2340
Query: 82 SRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSP 141
S S + +P V T + S+ H L D + G +P
Sbjct: 2341 SPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTP 2400
Query: 142 TKPGSQYYQYSSNNPRRRPLH--SSAMEVQTKKVRKVPPGLPSSVYA--------PSAST 191
P + S+ + P+ SSA T ++ S+ +A SAST
Sbjct: 2401 L-PVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSAST 2459
Query: 192 ADYNRDSPGYPSSKPATS-------TFPSSFFMQDGHH--SSDPWSSSSGMNQP-----G 237
D PG +S +T T SS D + P S+S+G P
Sbjct: 2460 GD-TTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDT 2518
Query: 238 YAGMLGNSSHIP--QSSSYCSLHPHE-RLSYPSHSSADINSSLP-----PMSTFHRSGTN 289
+ G+++ +P +SS + H ++ PS +S +SLP ST H +
Sbjct: 2519 PSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLP 2578
Query: 290 HYSTSSC----TPPANGTDSIMANRGSGA------AGSSQTGDALGKALASIYSPDHTNN 339
STSS T P TD+ A+ G S+ TGD + D ++
Sbjct: 2579 VTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDT-----TPLPVTDTSSA 2633
Query: 340 SFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPL----HSLQSRIEDRLERLDD 395
S PV + S+S G A +S+S + PL S S + D
Sbjct: 2634 STGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSVSTGHATSLPVTD 2693
Query: 396 AIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHR 455
A V HA +P H P + + + +G+ T L + S+ G H
Sbjct: 2694 ASSVFTGHATSLPVTIPSSASSGHTTPLPVTDAS--SVSTGHATSLPVTDASSVSTG-HA 2750
Query: 456 EDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKS 515
S + P+P + S ++ D P P GQ+ + + S
Sbjct: 2751 TPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPL--PVTDTSSASTGQATPLPVTSLSS 2808
Query: 516 DDEGDEN---LQDTKSS 529
GD + DT S+
Sbjct: 2809 VSTGDTTPLPVTDTSSA 2825
Score = 40.8 bits (94), Expect = 0.004
Identities = 103/454 (22%), Positives = 164/454 (36%), Gaps = 73/454 (16%)
Query: 29 PVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSP-------SRNYGDGTPYDHMT 81
PV+S P+S+++GH T V D SS + GH +P S + GD TP +T
Sbjct: 1010 PVTS----PSSVSTGHTTPLPVTDTSSEST----GHVTPLPVTSFSSASTGDSTPLP-VT 1060
Query: 82 SRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSP 141
S +++P V S + T + S+ H SL D + G +P
Sbjct: 1061 DTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTP 1120
Query: 142 TKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGY 201
P + S+ + P+ ++ V G + ++ AS+A S G
Sbjct: 1121 L-PVTDTSSASTGHATSLPVTDTS---------SVSTGHTTPLHVTDASSA-----STGQ 1165
Query: 202 PSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQP-----GYAGMLGNSSHIP--QSSSY 254
+ P TS S + P S+S+G P + G+++ +P +SS
Sbjct: 1166 ATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSV 1225
Query: 255 CSLHPHE-RLSYPSHSSADINSSLPPMSTFHRS----------GTNHYSTSSCTP-PANG 302
+ H ++ PS +S + LP T S T+ ST TP P
Sbjct: 1226 STDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTS 1285
Query: 303 TDSIMANRGS----GAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAG 358
T S + + S+ TG A + S+ S S PV SP S S G
Sbjct: 1286 TSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSA-----STGDTMPLPVTSPSSASTG 1340
Query: 359 TAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDM 418
+S S + PLH + + + L + + G +T +P
Sbjct: 1341 DTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLP------ 1394
Query: 419 HGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVG 452
+ PS +G+ T LL + S G
Sbjct: 1395 --VTSPS------SASTGHATPLLVTDTSSASTG 1420
Score = 39.7 bits (91), Expect = 0.009
Identities = 98/412 (23%), Positives = 151/412 (36%), Gaps = 55/412 (13%)
Query: 29 PVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSH 88
PV+S P+S ++G T V D SS + GH +P H+T S
Sbjct: 1330 PVTS----PSSASTGDTTPLPVTDASSVST----GHTTPL----------HVTDASSAST 1371
Query: 89 DNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQY 148
+P V S T + S+ H LL D + G +P P +
Sbjct: 1372 GQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPL-PVTDA 1430
Query: 149 YQYSSNNPRRRP--LHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKP 206
S+++ P + S+A T + S+ A S D + S G + P
Sbjct: 1431 SSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLP 1490
Query: 207 ATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGML-----GNSSHIPQSS-SYCSLHPH 260
TST +S H + P S+S+G P L G++ +P +S S S
Sbjct: 1491 VTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDT 1550
Query: 261 ERLSYPSHSSADINSSLP-PMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGS------G 313
L SS + P P+++ + T H T P TD+ A++G
Sbjct: 1551 TPLPVTDASSVSTGHTTPLPVTSPSSASTGH------TTPLPVTDTSSASKGDTTPLPVT 1604
Query: 314 AAGSSQTGDALGKALASIYS---------PDHTNNSFSSNPSTP--VGSPPSLSAGTAVW 362
+ S+ TG + S P +S S+ +TP V SP S S G A
Sbjct: 1605 SPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATP 1664
Query: 363 SRNGGQASSSPNYEGPL--HSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMP 412
+S+S + PL L S D RL + + + + G +T +P
Sbjct: 1665 LPVTSTSSASTGHATPLPVTGLSSATTDDTTRL--PVTDVSSASTGQATPLP 1714
Score = 36.6 bits (83), Expect = 0.077
Identities = 95/409 (23%), Positives = 149/409 (36%), Gaps = 81/409 (19%)
Query: 31 SSGKNGP------TSLASGHFTGSNVEDRSSSGSWGNGGHPSP-------SRNYGDGTPY 77
SSG P +S+++GH T V D SS + GH +P S + G TP
Sbjct: 2714 SSGHTTPLPVTDASSVSTGHATSLPVTDASSVST----GHATPLPVTDASSVSTGHATPL 2769
Query: 78 DHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPG 137
+ + + D P ++ S +S G+ + L S+ GD
Sbjct: 2770 PLTSLSSVSTGDTTPLPVTDT---------SSASTGQATPLPVTSLSSVSTGDTT----- 2815
Query: 138 TLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRD 197
L T S ++++ P SSA + S+ +A D +
Sbjct: 2816 PLPVTDTSSASTGHATSLPVTDT--SSASTGHATPLPDTDTSSASTGHATLLPVTDTSSA 2873
Query: 198 SPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQP-----------GYAGML---- 242
S G+ +S P T T S H + P S+S+G P G+A L
Sbjct: 2874 SIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTS 2933
Query: 243 ------GNSSHIPQSSSYCSLHPHER-LSYPSHSSADINSSLP-PMSTFHRSGTNHYSTS 294
G+++ +P + + + H L S SS + P P+++ + T H
Sbjct: 2934 PSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGH---- 2989
Query: 295 SCTPPANGTDSIMANRGSGAA------GSSQTGDALGKALASIYS---------PDHTNN 339
T P TD+ A+ G A S+ TGD + S P + +
Sbjct: 2990 --TTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLS 3047
Query: 340 SFSSNPST--PVGSPPSLSAG--TAVWSRNGGQASSSPNYEGPLHSLQS 384
S S+ +T PV SP S S G T + + AS+ P+ SL S
Sbjct: 3048 SVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSS 3096
Score = 35.0 bits (79), Expect = 0.22
Identities = 79/357 (22%), Positives = 129/357 (36%), Gaps = 32/357 (8%)
Query: 29 PVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHP--SPSRNYGDGTPYDHMTSRDLG 86
PV+S P+S ++GH T V D SS+ + P S Y T +T
Sbjct: 3106 PVTS----PSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSS 3161
Query: 87 SHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGS 146
S + +P V T + S+ H L + G +P P +
Sbjct: 3162 STGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPV-PVT 3220
Query: 147 QYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADY-NRDSPGYPSSK 205
S+ + P+ + T ++P SS A+ N S +
Sbjct: 3221 DTSSVSTGHATPLPV-TGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTM 3279
Query: 206 PATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHER-LS 264
P T PSS GH + P +S+S + G+++ +P +S+ + H L
Sbjct: 3280 PLPVTSPSS--ASTGHATPLPVTSTS-------SASTGHATPVPVTSTSSASTGHTTPLP 3330
Query: 265 YPSHSSADINSSLP-PMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDA 323
SSA + P P+++ + T H + T P++ + + A S+ TG A
Sbjct: 3331 VTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHA 3390
Query: 324 LGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAG-------TAVWSRNGGQASSSP 373
+ D ++ S PV S S+S G T S + GQA+ P
Sbjct: 3391 -----TPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLP 3442
Score = 34.7 bits (78), Expect = 0.29
Identities = 78/356 (21%), Positives = 129/356 (36%), Gaps = 39/356 (10%)
Query: 38 TSLASGHFTGSNVEDRSSSGSWGNGGHPSP-------SRNYGDGTPYDHMTSRDLGSHDN 90
+S ++GH T +V D SS + GH +P S + G TP +T S +
Sbjct: 983 SSASTGHTTPLHVTDASSVST----GHATPLPVTSPSSVSTGHTTPLP-VTDTSSESTGH 1037
Query: 91 LSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQ 150
++P V S + T + S+ H L + + G +P P +
Sbjct: 1038 VTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPL-PVTDTSS 1096
Query: 151 YSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATST 210
S+ + P+ ++ V T +P D + S G+ +S P T T
Sbjct: 1097 ASTGHATSLPVTDTS-SVSTGHTTPLP-------------VTDTSSASTGHATSLPVTDT 1142
Query: 211 FPSSFFMQDGHHSSDPWSSSSGMNQPGYAGML-----GNSSHIPQSSSYCSLHPHER-LS 264
S H +D S+S+G P L G+++ +P +S + H L
Sbjct: 1143 SSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLL 1202
Query: 265 YPSHSSADINSSLP-PMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDA 323
SSA + P P++ T+H ++ T P+ + S+ TG A
Sbjct: 1203 VTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQA 1262
Query: 324 LGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPL 379
S+ D ++ S PV S S S G +S+S + PL
Sbjct: 1263 -----TSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPL 1313
Score = 34.7 bits (78), Expect = 0.29
Identities = 88/356 (24%), Positives = 134/356 (37%), Gaps = 58/356 (16%)
Query: 37 PTSLASGHFTGSNVEDRSSSGSWGNGGH-------PSPSRNYGDGTPYDHMTSRDLGSHD 89
P+S +SGH T V D SS + GH + S + GD TP +T + S
Sbjct: 1846 PSSASSGHTTSLPVTDASSVST----GHATSLLVTDASSVSTGDTTPLP-VTDTNSASTG 1900
Query: 90 NLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYY 149
+ +P V T+ S S+ G ++L S GD L T P S
Sbjct: 1901 DTTPLHV-------TDASSVST-GHATSLPVTSLSSASTGDTT-----PLPVTSPSSA-- 1945
Query: 150 QYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSV---YAPSASTADYNRDSPGYPSSKP 206
SS + P+ + A V T +P SSV +A D + S G+ + P
Sbjct: 1946 --SSGHTTPLPV-TDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLP 2002
Query: 207 ATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIP-QSSSYCSLHPHERLSY 265
T T S G + P +S S + G+++ +P +S S L
Sbjct: 2003 VTDTSSVS----TGQATPLPVTSLS-------SASTGDTTPLPVTDTSSASTGQDTPLPV 2051
Query: 266 PSHSSADINSSLP-PMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDAL 324
S SS + P P+++ + T H + T ++ + + A S TG A
Sbjct: 2052 TSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHA- 2110
Query: 325 GKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAG-------TAVWSRNGGQASSSP 373
+++ D ++ S PV SP S S G T S + G A+S P
Sbjct: 2111 ----TALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLP 2162
>gi|239756681 PREDICTED: basic helix-loop-helix family, member a9
[Homo sapiens]
Length = 203
Score = 44.7 bits (104), Expect = 3e-04
Identities = 37/109 (33%), Positives = 51/109 (46%), Gaps = 12/109 (11%)
Query: 565 REKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQ 624
R K RRMA N RER R+ D NEAF L R ++ H K +K+ L +A+ I +L
Sbjct: 62 RSKARRMAANVRERKRILDYNEAFNALRRALR-HDLGGKRLSKIATLRRAIHRIAALSLV 120
Query: 625 VRERNLNPKAAC--------LKRREEEKVSSEPPPLSLAGPHPGMGDAS 665
+R + P+ C R + + PPP AGP DA+
Sbjct: 121 LR-ASPAPRGPCGHLECHGPAARGDTGDTGASPPP--PAGPSLARPDAA 166
>gi|239751178 PREDICTED: basic helix-loop-helix family, member a9
[Homo sapiens]
Length = 235
Score = 44.7 bits (104), Expect = 3e-04
Identities = 37/109 (33%), Positives = 51/109 (46%), Gaps = 12/109 (11%)
Query: 565 REKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQ 624
R K RRMA N RER R+ D NEAF L R ++ H K +K+ L +A+ I +L
Sbjct: 62 RSKARRMAANVRERKRILDYNEAFNALRRALR-HDLGGKRLSKIATLRRAIHRIAALSLV 120
Query: 625 VRERNLNPKAAC--------LKRREEEKVSSEPPPLSLAGPHPGMGDAS 665
+R + P+ C R + + PPP AGP DA+
Sbjct: 121 LR-ASPAPRGPCGHLECHGPAARGDTGDTGASPPP--PAGPSLARPDAA 166
>gi|239745666 PREDICTED: basic helix-loop-helix family, member a9
[Homo sapiens]
Length = 235
Score = 44.7 bits (104), Expect = 3e-04
Identities = 37/109 (33%), Positives = 51/109 (46%), Gaps = 12/109 (11%)
Query: 565 REKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQ 624
R K RRMA N RER R+ D NEAF L R ++ H K +K+ L +A+ I +L
Sbjct: 62 RSKARRMAANVRERKRILDYNEAFNALRRALR-HDLGGKRLSKIATLRRAIHRIAALSLV 120
Query: 625 VRERNLNPKAAC--------LKRREEEKVSSEPPPLSLAGPHPGMGDAS 665
+R + P+ C R + + PPP AGP DA+
Sbjct: 121 LR-ASPAPRGPCGHLECHGPAARGDTGDTGASPPP--PAGPSLARPDAA 166
>gi|98986461 neurogenic differentiation 2 [Homo sapiens]
Length = 382
Score = 44.3 bits (103), Expect = 4e-04
Identities = 38/148 (25%), Positives = 68/148 (45%), Gaps = 11/148 (7%)
Query: 486 DLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSS-------EDKKLDDDK 538
D PP P G PG G + ++ ++ ++ + L + K E+++ +++
Sbjct: 35 DAPPPPPPAPG--PGAPGPARAAKPVPLRGEEGTEATLAEVKEEGELGGEEEEEEEEEEG 92
Query: 539 KDIKSITRSRSSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLH 598
D R + +T + + ER K RR NARER R+ D+N A L ++V +
Sbjct: 93 LDEAEGERPKKRGPKKRKMT-KARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCY 151
Query: 599 LKSDKPQTKLLILHQAVAVILSLEQQVR 626
K+ K +K+ L A I +L + +R
Sbjct: 152 SKTQK-LSKIETLRLAKNYIWALSEILR 178
>gi|5453726 leucine rich repeat (in FLII) interacting protein 2
isoform 1 [Homo sapiens]
Length = 721
Score = 43.9 bits (102), Expect = 5e-04
Identities = 69/264 (26%), Positives = 103/264 (39%), Gaps = 23/264 (8%)
Query: 78 DHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPG 137
D ++ R +GSH +SR+ S S+S +G + H+ L G D N
Sbjct: 99 DALSIRSVGSHRYDMFKDRSSRLSSLNHSYSHS-HGMKKRSSDSHKDLLSGLYFDQRNYS 157
Query: 138 TLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTAD---- 193
+L +KP S YY S++ PL T K + P S + SAS A
Sbjct: 158 SLRHSKPTSAYYTRQSSSLYSDPL-------ATYKSDRASPTANSGLLR-SASLASLYNG 209
Query: 194 --YNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWS--SSSGMNQPGYAGMLGNSSHIP 249
YN P PS S+ SS G + D S SS ++ ++ + +
Sbjct: 210 GLYNPYGPRTPSECSYYSSRISSARSSPGFTNDDTASIVSSDRASRGRRESVVSAADYFS 269
Query: 250 QSSSYCSLHPH-ERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMA 308
+S+ S+ + +S P SS D S + R + +++S T P +G S
Sbjct: 270 RSNRRGSVVSEVDDISIPDLSSLDEKSDKQYAENYTRPSSR--NSASATTPLSGNSS--- 324
Query: 309 NRGSGAAGSSQTGDALGKALASIY 332
RGSG S D L IY
Sbjct: 325 RRGSGDTSSLIDPDTSLSELRDIY 348
>gi|7662230 ring finger protein 40 [Homo sapiens]
Length = 1001
Score = 43.9 bits (102), Expect = 5e-04
Identities = 62/293 (21%), Positives = 106/293 (36%), Gaps = 40/293 (13%)
Query: 370 SSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPG-GHGDMHGIIGPSHNG 428
SS N+ L R + +L + I LR A G + + P GH + G+ P+
Sbjct: 488 SSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSAHSTPNLGHPEDSGVSAPAPGK 547
Query: 429 AMGGLGS--------------GYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPV 474
GG G G T S + L+ G+ P
Sbjct: 548 EEGGPGPVSTPDNRKEMAPVPGTTTTTTSVKKEELVPSEEDFQGIT------------PG 595
Query: 475 PQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKL 534
Q P P+ P ++ P L V+S S D +++TK E + L
Sbjct: 596 AQGPSSRGREPEARPKRELREREGPSLGPPPVASALSRA---DREKAKVEETKRKESELL 652
Query: 535 DDDKKDIKSITRSRSSNNDDEDLTPEQ-KAEREKERRMANNARERLRVRDINEAFKELGR 593
+ ++K S+ D+ K +R+K + MA + + V ++ +EL
Sbjct: 653 KGLRAELKKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELE- 711
Query: 594 MVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVS 646
+ D+ ++K + A+ I E+Q+ +L K K+ EE +S
Sbjct: 712 ------ERDRRESKKIADEDALRRIRQAEEQI--EHLQRKLGATKQEEEALLS 756
>gi|226498192 atonal homolog 8 [Homo sapiens]
Length = 321
Score = 43.5 bits (101), Expect = 6e-04
Identities = 44/150 (29%), Positives = 63/150 (42%), Gaps = 30/150 (20%)
Query: 475 PQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKL 534
P P SA PP+ R PP G+S S S + + N QD+ +S K+
Sbjct: 160 PARPAPSAPPAPPAPPESTVRPAPPTRPGESSYSSISHVIYN-----NHQDSSASPRKRP 214
Query: 535 DDD---KKDIKSITRSRSSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKEL 591
+ +IK++ ++ RR+ NARER RV I+ AF+ L
Sbjct: 215 GEATAASSEIKAL---------------------QQTRRLLANARERTRVHTISAAFEAL 253
Query: 592 GRMVQLHLKSDKPQTKLLILHQAVAVILSL 621
+ V + K +KL IL A ILSL
Sbjct: 254 RKQVPCYSYGQK-LSKLAILRIACNYILSL 282
>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
sapiens]
Length = 661
Score = 42.7 bits (99), Expect = 0.001
Identities = 75/320 (23%), Positives = 107/320 (33%), Gaps = 35/320 (10%)
Query: 71 YGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGD 130
YG T + ++ ++ + + S Q T G+ + Y + Q + Q + G
Sbjct: 44 YGQPTDVSYTQAQTTATYGQTA--YATSYGQPPTVEGTSTGYTTPTAPQA-YSQPVQGYG 100
Query: 131 MDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSAS 190
+ T + T + Y S+ + T R P+ P +S
Sbjct: 101 TGAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSS 160
Query: 191 TADYNRDSPGYPSSKPATSTFPSSFFMQ----------DGHHSSDP----WSSSSGMNQP 236
T YN+ S GY S + P S+ MQ + S+ P SS S N
Sbjct: 161 TGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTY 220
Query: 237 GYAGMLGNSSHIPQSSSYCSLHPHERLSYP----SHSSA-----DINSSLPPMSTF---H 284
G G S Q SSY P SYP S+S A +SS S+F H
Sbjct: 221 GQPSSYGQQSSYGQQSSYGQQPP---TSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDH 277
Query: 285 RSGTNHYSTSS---CTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSF 341
S Y S P N + S NRG G G + G + G
Sbjct: 278 PSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGG 337
Query: 342 SSNPSTPVGSPPSLSAGTAV 361
+ P P+ P L G V
Sbjct: 338 FNKPGGPMDEGPDLDLGPPV 357
>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
Length = 587
Score = 42.7 bits (99), Expect = 0.001
Identities = 77/368 (20%), Positives = 131/368 (35%), Gaps = 52/368 (14%)
Query: 31 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 90
SS ++ T+L+ T S V + S++ H P + P D T+ L H
Sbjct: 130 SSPRSPATTLSPASTTSSGVSEESTTS------HSRPGSTHTTAFP-DSTTTPGLSRHST 182
Query: 91 LS---PPFVNSRI--QSKTERGSYSSYGRESNLQGCHQQSLLGGD---MDMGNPGTLSPT 142
S P ++ + S T G + G +L G + G T +
Sbjct: 183 TSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHS 242
Query: 143 KPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYP 202
PGS + ++ + ++ V + G P + +P++ST SPG
Sbjct: 243 SPGSTHTTLFPDSTTSSGIVEASTRVHSST------GSPRTTLSPASST------SPGLQ 290
Query: 203 SSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPG--YAGMLGNS--SHIPQSSSYCSLH 258
A T P+S H + P S+++ + Y G++ +H P SS+
Sbjct: 291 GESTAFQTHPAST-----HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSG-- 343
Query: 259 PHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPAN-------------GTDS 305
H S HSS D + + P + SG + S++S + P + G
Sbjct: 344 -HSEKSTIFHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQ 402
Query: 306 IMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRN 365
S + T D + +P + ++ S PS+ + S S+ T S
Sbjct: 403 EPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEE 462
Query: 366 GGQASSSP 373
SSP
Sbjct: 463 STTVHSSP 470
>gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]
Length = 456
Score = 42.7 bits (99), Expect = 0.001
Identities = 77/368 (20%), Positives = 131/368 (35%), Gaps = 52/368 (14%)
Query: 31 SSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDN 90
SS ++ T+L+ T S V + S++ H P + P D T+ L H
Sbjct: 24 SSPRSPATTLSPASTTSSGVSEESTTS------HSRPGSTHTTAFP-DSTTTPGLSRHST 76
Query: 91 LS---PPFVNSRI--QSKTERGSYSSYGRESNLQGCHQQSLLGGD---MDMGNPGTLSPT 142
S P ++ + S T G + G +L G + G T +
Sbjct: 77 TSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHS 136
Query: 143 KPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYP 202
PGS + ++ + ++ V + G P + +P++ST SPG
Sbjct: 137 SPGSTHTTLFPDSTTSSGIVEASTRVHSST------GSPRTTLSPASST------SPGLQ 184
Query: 203 SSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPG--YAGMLGNS--SHIPQSSSYCSLH 258
A T P+S H + P S+++ + Y G++ +H P SS+
Sbjct: 185 GESTAFQTHPAST-----HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSG-- 237
Query: 259 PHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPAN-------------GTDS 305
H S HSS D + + P + SG + S++S + P + G
Sbjct: 238 -HSEKSTIFHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQ 296
Query: 306 IMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRN 365
S + T D + +P + ++ S PS+ + S S+ T S
Sbjct: 297 EPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEE 356
Query: 366 GGQASSSP 373
SSP
Sbjct: 357 STTVHSSP 364
>gi|4885075 atonal homolog 1 [Homo sapiens]
Length = 354
Score = 42.4 bits (98), Expect = 0.001
Identities = 58/233 (24%), Positives = 87/233 (37%), Gaps = 45/233 (19%)
Query: 468 LPNQVPVPQLPVQ-SATSPDLNPPQ-------DPYRGMPPGLQG-----------QSVSS 508
LP P PQ P A + PP+ DP + P LQG S
Sbjct: 28 LPQPPPPPQPPATLQAREHPVYPPELSLLDSTDPRAWLAPTLQGICTARAAQYLLHSPEL 87
Query: 509 GSSEIKS-----DDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKA 563
G+SE + D G+ + + + K K + + + + DE Q+A
Sbjct: 88 GASEAAAPRDEVDGRGELVRRSSGGASSSKSPGPVKVREQLCKLKGGVVVDELGCSRQRA 147
Query: 564 ER-------EKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVA 616
+K+RR+A NARER R+ +N AF +L R V +DK +K L A
Sbjct: 148 PSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQL-RNVIPSFNNDKKLSKYETLQMAQI 206
Query: 617 VILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMG 669
I +L + L + PPP S H + A+++ G
Sbjct: 207 YINALSE-------------LLQTPSGGEQPPPPPASCKSDHHHLRTAASYEG 246
>gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens]
Length = 922
Score = 42.4 bits (98), Expect = 0.001
Identities = 95/385 (24%), Positives = 139/385 (36%), Gaps = 66/385 (17%)
Query: 28 PPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPY-----DHMTS 82
PP S G + PT + +G G PS + G +P +TS
Sbjct: 415 PPTSQGLSNPTPVIAG------------------GSTPSVAGPLGVNSPLLSALKGFLTS 456
Query: 83 RDLG-SHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPG-TLS 140
D + + V S + S + +S S C+ S + PG L
Sbjct: 457 NDTNLINSSALSSAVTSGLASLSSLTLQNSDSSASAPNKCYAPSAIPTPQRTSTPGLALF 516
Query: 141 PTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSS---VYAPSASTADYNRD 197
P P S++ P P+ S + VP SS + P T+D +
Sbjct: 517 PGLPSP--VANSTSTPLTLPV-QSPLATAASASTSVPVSCGSSASLLRGPHPGTSDLHIS 573
Query: 198 SPGYPSSKPA------TSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQS 251
S ++ P TS PS+F + HS +P + G++ G G S+ +P S
Sbjct: 574 STPAATTLPVMIKTEPTSPTPSAF--KGPSHSGNPSHGTLGLS--GTLGRAYTSTSVPIS 629
Query: 252 SSYC---SLHPHERLSYPSHSSADINS-SLPPMSTFHRSGTNHYSTSSCTP--------- 298
S C +L LS P + S ++S SLPP H S T + P
Sbjct: 630 LSACLNPALSGLSSLSTPLNGSNPLSSISLPP----HGSSTPIAPVFTALPSFTSLTNNF 685
Query: 299 PANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSS-NPSTPVGSPP-SLS 356
P G S+ N GS + S+ P T S + S PV + P L+
Sbjct: 686 PLTGNPSL--NPSVSLPGSLIATSSTAATSTSLPHPSSTAAVLSGLSASAPVSAAPFPLN 743
Query: 357 AGTAVWS----RNGGQASSSPNYEG 377
TAV S G +SS+P+Y G
Sbjct: 744 LSTAVPSLFSVTQGPLSSSNPSYPG 768
>gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens]
Length = 944
Score = 42.4 bits (98), Expect = 0.001
Identities = 95/385 (24%), Positives = 139/385 (36%), Gaps = 66/385 (17%)
Query: 28 PPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPY-----DHMTS 82
PP S G + PT + +G G PS + G +P +TS
Sbjct: 437 PPTSQGLSNPTPVIAG------------------GSTPSVAGPLGVNSPLLSALKGFLTS 478
Query: 83 RDLG-SHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPG-TLS 140
D + + V S + S + +S S C+ S + PG L
Sbjct: 479 NDTNLINSSALSSAVTSGLASLSSLTLQNSDSSASAPNKCYAPSAIPTPQRTSTPGLALF 538
Query: 141 PTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSS---VYAPSASTADYNRD 197
P P S++ P P+ S + VP SS + P T+D +
Sbjct: 539 PGLPSP--VANSTSTPLTLPV-QSPLATAASASTSVPVSCGSSASLLRGPHPGTSDLHIS 595
Query: 198 SPGYPSSKPA------TSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQS 251
S ++ P TS PS+F + HS +P + G++ G G S+ +P S
Sbjct: 596 STPAATTLPVMIKTEPTSPTPSAF--KGPSHSGNPSHGTLGLS--GTLGRAYTSTSVPIS 651
Query: 252 SSYC---SLHPHERLSYPSHSSADINS-SLPPMSTFHRSGTNHYSTSSCTP--------- 298
S C +L LS P + S ++S SLPP H S T + P
Sbjct: 652 LSACLNPALSGLSSLSTPLNGSNPLSSISLPP----HGSSTPIAPVFTALPSFTSLTNNF 707
Query: 299 PANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSS-NPSTPVGSPP-SLS 356
P G S+ N GS + S+ P T S + S PV + P L+
Sbjct: 708 PLTGNPSL--NPSVSLPGSLIATSSTAATSTSLPHPSSTAAVLSGLSASAPVSAAPFPLN 765
Query: 357 AGTAVWS----RNGGQASSSPNYEG 377
TAV S G +SS+P+Y G
Sbjct: 766 LSTAVPSLFSVTQGPLSSSNPSYPG 790
>gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo
sapiens]
Length = 1004
Score = 42.0 bits (97), Expect = 0.002
Identities = 55/214 (25%), Positives = 87/214 (40%), Gaps = 17/214 (7%)
Query: 68 SRNYGDGTPYDHMTSRDLGSHDNLSPPF--VNSRIQSKTERGSYSSYGRESNLQGCHQQS 125
S+++ D +P + ++ PP + R +S TE+ + R+ + + +
Sbjct: 54 SKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDRSSTEKHDWDPPDRKVDTRKFRSEP 113
Query: 126 LLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPP--GLPSS 183
+ + G L +P S YQ S + RP+ S++M +K RK P G P
Sbjct: 114 RSIFEYEPGKSSILQHERPAS-LYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGPPRG 172
Query: 184 VYAPSASTADYNR-DSPGYPS--SKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAG 240
+ SAS R D PG + +K TS+ PSS G S S Y+G
Sbjct: 173 LGDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKGGDDSKICPSLC-----SYSG 227
Query: 241 MLGNSSHIPQSSSYCSLHPHERLSYPSHSSADIN 274
+ GN S YCS + + L P S I+
Sbjct: 228 LNGNPS---SELDYCSTY-RQHLDVPRDSPRAIS 257
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.126 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,868,690
Number of Sequences: 37866
Number of extensions: 1752852
Number of successful extensions: 10381
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 115
Number of HSP's successfully gapped in prelim test: 528
Number of HSP's that attempted gapping in prelim test: 8521
Number of HSP's gapped (non-prelim): 1912
length of query: 671
length of database: 18,247,518
effective HSP length: 109
effective length of query: 562
effective length of database: 14,120,124
effective search space: 7935509688
effective search space used: 7935509688
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.