Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 145279222
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|145279222 WD repeat domain 66 [Homo sapiens]
(1149 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|145279222 WD repeat domain 66 [Homo sapiens] 2326 0.0
gi|223029510 echinoderm microtubule associated protein like 4 is... 82 3e-15
gi|19923497 echinoderm microtubule associated protein like 4 iso... 82 3e-15
gi|223005862 echinoderm microtubule associated protein like 6 [H... 77 7e-14
gi|34485720 echinoderm microtubule associated protein like 5 [Ho... 67 7e-11
gi|94400919 WD repeat domain 90 [Homo sapiens] 57 1e-07
gi|56790932 echinoderm microtubule associated protein like 1 iso... 56 2e-07
gi|56790930 echinoderm microtubule associated protein like 1 iso... 56 2e-07
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 55 3e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 55 3e-07
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 55 4e-07
gi|148746195 trichohyalin [Homo sapiens] 55 4e-07
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 55 4e-07
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 55 5e-07
gi|221219020 NYD-SP11 protein [Homo sapiens] 54 7e-07
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens] 53 2e-06
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 53 2e-06
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 53 2e-06
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 51 6e-06
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 50 9e-06
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] 50 9e-06
gi|110227615 echinoderm microtubule associated protein like 3 [H... 50 9e-06
gi|157738619 smoothelin-like 1 [Homo sapiens] 50 9e-06
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens] 50 2e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 50 2e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 50 2e-05
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 50 2e-05
gi|22749037 WD repeat domain 65 [Homo sapiens] 50 2e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 49 3e-05
gi|6912356 echinoderm microtubule associated protein like 2 [Hom... 49 3e-05
>gi|145279222 WD repeat domain 66 [Homo sapiens]
Length = 1149
Score = 2326 bits (6029), Expect = 0.0
Identities = 1149/1149 (100%), Positives = 1149/1149 (100%)
Query: 1 MSDAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEE 60
MSDAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEE
Sbjct: 1 MSDAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEE 60
Query: 61 EGEEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSI 120
EGEEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSI
Sbjct: 61 EGEEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSI 120
Query: 121 TSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSG 180
TSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSG
Sbjct: 121 TSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSG 180
Query: 181 ELEEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESLVSSTTEDILFQK 240
ELEEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESLVSSTTEDILFQK
Sbjct: 181 ELEEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESLVSSTTEDILFQK 240
Query: 241 DKSTPVYPLTMTWSFGWNSSLPVYYIREERQRVLLYVCAHTAIIYNVFRNNQYHLQGHAN 300
DKSTPVYPLTMTWSFGWNSSLPVYYIREERQRVLLYVCAHTAIIYNVFRNNQYHLQGHAN
Sbjct: 241 DKSTPVYPLTMTWSFGWNSSLPVYYIREERQRVLLYVCAHTAIIYNVFRNNQYHLQGHAN 300
Query: 301 IISCLCVSEDRRWIATADKGPDCLVIIWDSFTGIPVHTIFDSCPEGNGIMAMAMTHDAKY 360
IISCLCVSEDRRWIATADKGPDCLVIIWDSFTGIPVHTIFDSCPEGNGIMAMAMTHDAKY
Sbjct: 301 IISCLCVSEDRRWIATADKGPDCLVIIWDSFTGIPVHTIFDSCPEGNGIMAMAMTHDAKY 360
Query: 361 LATISDAEVQKVCIWKWTLAVETPACTLELPTEYGVQNYVTFNPTNNKELVSNSKTRAIY 420
LATISDAEVQKVCIWKWTLAVETPACTLELPTEYGVQNYVTFNPTNNKELVSNSKTRAIY
Sbjct: 361 LATISDAEVQKVCIWKWTLAVETPACTLELPTEYGVQNYVTFNPTNNKELVSNSKTRAIY 420
Query: 421 YAWYEERDTLAHSAPLLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPS 480
YAWYEERDTLAHSAPLLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPS
Sbjct: 421 YAWYEERDTLAHSAPLLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPS 480
Query: 481 SASTFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIVNWYSHLK 540
SASTFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIVNWYSHLK
Sbjct: 481 SASTFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIVNWYSHLK 540
Query: 541 LGAIRTLSFSKTPATPPTEKSNYPPDCTLKGDLFVLRNFIIGTSDAAVYHLTTDGTKLEK 600
LGAIRTLSFSKTPATPPTEKSNYPPDCTLKGDLFVLRNFIIGTSDAAVYHLTTDGTKLEK
Sbjct: 541 LGAIRTLSFSKTPATPPTEKSNYPPDCTLKGDLFVLRNFIIGTSDAAVYHLTTDGTKLEK 600
Query: 601 LFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFEKGLGVQSLTYNPE 660
LFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFEKGLGVQSLTYNPE
Sbjct: 601 LFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFEKGLGVQSLTYNPE 660
Query: 661 GALLGAGFTEGTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADRSFTVAVY 720
GALLGAGFTEGTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADRSFTVAVY
Sbjct: 661 GALLGAGFTEGTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADRSFTVAVY 720
Query: 721 MLVVRNGQRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKD 780
MLVVRNGQRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKD
Sbjct: 721 MLVVRNGQRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKD 780
Query: 781 HLEVLDIHHTDQGCYPTCMVWYPPLTRELFLLICNSGYKVKLFNATTKMCRKTLLGPAYG 840
HLEVLDIHHTDQGCYPTCMVWYPPLTRELFLLICNSGYKVKLFNATTKMCRKTLLGPAYG
Sbjct: 781 HLEVLDIHHTDQGCYPTCMVWYPPLTRELFLLICNSGYKVKLFNATTKMCRKTLLGPAYG 840
Query: 841 SPIEQTQVLPVRSMAELQKRYLVFINRDKVGLQILPVDGNPHKTSAIVCHPNGVAGMAVS 900
SPIEQTQVLPVRSMAELQKRYLVFINRDKVGLQILPVDGNPHKTSAIVCHPNGVAGMAVS
Sbjct: 841 SPIEQTQVLPVRSMAELQKRYLVFINRDKVGLQILPVDGNPHKTSAIVCHPNGVAGMAVS 900
Query: 901 YDGCYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGLLSGGREGKFYRELEDYF 960
YDGCYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGLLSGGREGKFYRELEDYF
Sbjct: 901 YDGCYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGLLSGGREGKFYRELEDYF 960
Query: 961 YYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKIDDIFNEIKFGEYVDTGK 1020
YYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKIDDIFNEIKFGEYVDTGK
Sbjct: 961 YYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKIDDIFNEIKFGEYVDTGK 1020
Query: 1021 LIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGKKAIRREDFLRLLVTKGE 1080
LIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGKKAIRREDFLRLLVTKGE
Sbjct: 1021 LIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGKKAIRREDFLRLLVTKGE 1080
Query: 1081 HMTEEEMLDCFASLFGLNPEGWKSEPATCSVKGSEICLEEELPDEITAEIFATEILGLTI 1140
HMTEEEMLDCFASLFGLNPEGWKSEPATCSVKGSEICLEEELPDEITAEIFATEILGLTI
Sbjct: 1081 HMTEEEMLDCFASLFGLNPEGWKSEPATCSVKGSEICLEEELPDEITAEIFATEILGLTI 1140
Query: 1141 SEDSGQDGQ 1149
SEDSGQDGQ
Sbjct: 1141 SEDSGQDGQ 1149
>gi|223029510 echinoderm microtubule associated protein like 4
isoform b [Homo sapiens]
Length = 923
Score = 82.0 bits (201), Expect = 3e-15
Identities = 141/709 (19%), Positives = 262/709 (36%), Gaps = 131/709 (18%)
Query: 245 PVYPLTMTWSFGWNSS---LPVYYIREERQRVLLYVCAHTAIIYNVFRNNQYHLQGHANI 301
P L + W++G+ VY + ++Y A +++N Q H GH +
Sbjct: 197 PPEKLKLEWAYGYRGKDCRANVYLLPTGE---IVYFIASVVVLFNYEERTQRHYLGHTDC 253
Query: 302 ISCLCVSEDRRWIAT-----ADKGPDCL---VIIWDSFTGIPVHTI-FDSCPEGNGIMAM 352
+ CL + D+ IAT DK L V +WDS T + I + G G +
Sbjct: 254 VKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVTLSTLQIIGLGTFERGVGCLDF 313
Query: 353 AMTHDAKYLATISDAEVQKVCIWKWTLAVETPACTLELPTEYGVQNYVTFNPTNNKELVS 412
+ +L I D+ + +W W + A E+ T V V F+PT+ +++
Sbjct: 314 SKADSGVHLCVIDDSNEHMLTVWDW----QKKAKGAEIKTTNEVVLAVEFHPTDANTIIT 369
Query: 413 NSKTRAIYYAWYEERDTLAHSAPLLTEK--TFNKL-VGKFSQSIFHLNLTQILSATMEGK 469
K+ ++ W S LT K F K KF Q + L +L+ G
Sbjct: 370 CGKSHIFFWTW---------SGNSLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGV 420
Query: 470 LVVWDIHRPPSSASTFLGFPYIKPCKLVHLQKE-------GITVLTTIDSYIVTGDIKG- 521
+++W S +T P P + + K+ T+ + ++TG K
Sbjct: 421 MLIW-------SKTTVEPTPGKGPKGVYQISKQIKAHDGSVFTLCQMRNGMLLTGGGKDR 473
Query: 522 NIKFYDHTLS------IVNWYSHLKLGAIRTLSFSKTPATPPTEKSNYPPDCTLKGDLFV 575
I +DH L+ + + Y G IR ++ K
Sbjct: 474 KIILWDHDLNPEREIEVPDQY-----GTIRAVAEGKAD---------------------- 506
Query: 576 LRNFIIGTSDAAVYHLT-TDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWN 634
F++GTS + T DG ++E D + ++ HP++ L+ + + +WN
Sbjct: 507 --QFLVGTSRNFILRGTFNDGFQIE--VQGHTDELWGLATHPFKDLLLTCAQDRQVCLWN 562
Query: 635 YENKQYLFSRVFEKGLGVQSLTYNPEGALLGAGFTEGTVYILDAMSLENESPEPFKYSRT 694
+ ++R+ ++ ++P G ++ G G ++LDA + + S +
Sbjct: 563 SMEHRLEWTRLVDE--PGHCADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQL 620
Query: 695 SVTHISFSHDSQYMATADRSFTVAVYMLVVRNGQRVWEYLARLRSHRKSIRSLLFGVYLD 754
SV + +S D ++A S +Y+ VV R + R H I L +
Sbjct: 621 SV--MRYSIDGTFLAVG--SHDNFIYLYVVSENGRKYSRYGRCTGHSSYITHLDW----S 672
Query: 755 SNEPRLLSLGTDRLLIEYDLLRSYKDHLEVLDIHHTDQGCYPTCMVWYPPLTRELFLLIC 814
+ ++S D ++ +D+ K D D Y TC++
Sbjct: 673 PDNKYIMSNSGDYEILYWDIPNGCKLIRNRSDCKDIDWTTY-TCVL-------------- 717
Query: 815 NSGYKVKLFNATTKMCRKTLLGPAYGSPIEQTQVLPVRSMAELQKRYLVFINRD--KVGL 872
G++V +G E + + ++ R ++ + D KV L
Sbjct: 718 --GFQV------------------FGVWPEGSDGTDINALVRSHNRKVIAVADDFCKVHL 757
Query: 873 QILPVDGNPHKTSAIVCHPNGVAGMAVSYDGCYAFTAGGHDRSVVQWKI 921
P + H + V ++ +++ + + GG D S++QWK+
Sbjct: 758 FQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKDMSIIQWKL 806
>gi|19923497 echinoderm microtubule associated protein like 4
isoform a [Homo sapiens]
Length = 981
Score = 82.0 bits (201), Expect = 3e-15
Identities = 141/709 (19%), Positives = 262/709 (36%), Gaps = 131/709 (18%)
Query: 245 PVYPLTMTWSFGWNSS---LPVYYIREERQRVLLYVCAHTAIIYNVFRNNQYHLQGHANI 301
P L + W++G+ VY + ++Y A +++N Q H GH +
Sbjct: 255 PPEKLKLEWAYGYRGKDCRANVYLLPTGE---IVYFIASVVVLFNYEERTQRHYLGHTDC 311
Query: 302 ISCLCVSEDRRWIAT-----ADKGPDCL---VIIWDSFTGIPVHTI-FDSCPEGNGIMAM 352
+ CL + D+ IAT DK L V +WDS T + I + G G +
Sbjct: 312 VKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVTLSTLQIIGLGTFERGVGCLDF 371
Query: 353 AMTHDAKYLATISDAEVQKVCIWKWTLAVETPACTLELPTEYGVQNYVTFNPTNNKELVS 412
+ +L I D+ + +W W + A E+ T V V F+PT+ +++
Sbjct: 372 SKADSGVHLCVIDDSNEHMLTVWDW----QKKAKGAEIKTTNEVVLAVEFHPTDANTIIT 427
Query: 413 NSKTRAIYYAWYEERDTLAHSAPLLTEK--TFNKL-VGKFSQSIFHLNLTQILSATMEGK 469
K+ ++ W S LT K F K KF Q + L +L+ G
Sbjct: 428 CGKSHIFFWTW---------SGNSLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGV 478
Query: 470 LVVWDIHRPPSSASTFLGFPYIKPCKLVHLQKE-------GITVLTTIDSYIVTGDIKG- 521
+++W S +T P P + + K+ T+ + ++TG K
Sbjct: 479 MLIW-------SKTTVEPTPGKGPKGVYQISKQIKAHDGSVFTLCQMRNGMLLTGGGKDR 531
Query: 522 NIKFYDHTLS------IVNWYSHLKLGAIRTLSFSKTPATPPTEKSNYPPDCTLKGDLFV 575
I +DH L+ + + Y G IR ++ K
Sbjct: 532 KIILWDHDLNPEREIEVPDQY-----GTIRAVAEGKAD---------------------- 564
Query: 576 LRNFIIGTSDAAVYHLT-TDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWN 634
F++GTS + T DG ++E D + ++ HP++ L+ + + +WN
Sbjct: 565 --QFLVGTSRNFILRGTFNDGFQIE--VQGHTDELWGLATHPFKDLLLTCAQDRQVCLWN 620
Query: 635 YENKQYLFSRVFEKGLGVQSLTYNPEGALLGAGFTEGTVYILDAMSLENESPEPFKYSRT 694
+ ++R+ ++ ++P G ++ G G ++LDA + + S +
Sbjct: 621 SMEHRLEWTRLVDE--PGHCADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQL 678
Query: 695 SVTHISFSHDSQYMATADRSFTVAVYMLVVRNGQRVWEYLARLRSHRKSIRSLLFGVYLD 754
SV + +S D ++A S +Y+ VV R + R H I L +
Sbjct: 679 SV--MRYSIDGTFLAVG--SHDNFIYLYVVSENGRKYSRYGRCTGHSSYITHLDW----S 730
Query: 755 SNEPRLLSLGTDRLLIEYDLLRSYKDHLEVLDIHHTDQGCYPTCMVWYPPLTRELFLLIC 814
+ ++S D ++ +D+ K D D Y TC++
Sbjct: 731 PDNKYIMSNSGDYEILYWDIPNGCKLIRNRSDCKDIDWTTY-TCVL-------------- 775
Query: 815 NSGYKVKLFNATTKMCRKTLLGPAYGSPIEQTQVLPVRSMAELQKRYLVFINRD--KVGL 872
G++V +G E + + ++ R ++ + D KV L
Sbjct: 776 --GFQV------------------FGVWPEGSDGTDINALVRSHNRKVIAVADDFCKVHL 815
Query: 873 QILPVDGNPHKTSAIVCHPNGVAGMAVSYDGCYAFTAGGHDRSVVQWKI 921
P + H + V ++ +++ + + GG D S++QWK+
Sbjct: 816 FQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKDMSIIQWKL 864
>gi|223005862 echinoderm microtubule associated protein like 6 [Homo
sapiens]
Length = 1958
Score = 77.4 bits (189), Expect = 7e-14
Identities = 93/490 (18%), Positives = 179/490 (36%), Gaps = 57/490 (11%)
Query: 241 DKSTPVYPLTMTWSFGWNSSLPVYYIREERQRVLLYVCAHTAIIYNVFRNNQYHLQGHAN 300
D++ P L + W +G+ + + ++Y A ++YN ++Q GH +
Sbjct: 3 DRTAPRCQLRLEWVYGYRGHQCRNNLYYTAGKEVVYFVAGVGVVYNTREHSQKFFLGHND 62
Query: 301 IISCLCVSEDRRWIATADKGPDCLVIIWDSFTGIPVHTIFDSCPEGNGIMAMAMTHDAKY 360
I L + D+ +AT G + + IWDS+ V + D +G+ +A D +
Sbjct: 63 DIISLALHPDKTLVATGQVGKEPYICIWDSYNVQTVSLLKD--VHTHGVACLAFDSDGQR 120
Query: 361 LATISDAEVQKVCIWKWTLAVETPACTLELPTEYGVQNYVTFNPTNNKELVSNSKTRAIY 420
LA++ VCIW W + T + ++++P +VS +
Sbjct: 121 LASVGLDAKNTVCIWDWRKGKLLASATGHSDRIFD----ISWDPYQPNRVVSCGVKHIKF 176
Query: 421 YAWYEERDTLAHSAPLLTEKTFNKLVGKFSQSIFHLNLTQ---ILSATMEGKLVVWDIHR 477
+ TL +A F K G Q+I L + S + G + VW
Sbjct: 177 W-------TLCGNALTAKRGIFGK-TGDL-QTILCLACAKEDITYSGALNGDIYVWK--- 224
Query: 478 PPSSASTFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIVNWYS 537
G ++ + H GI + + TG G I+ +D
Sbjct: 225 ---------GLNLVRTIQGAH--SAGIFSMYACEEGFATGGRDGCIRLWD---------- 263
Query: 538 HLKLGAIRTLSFSKTPATPPTEKSNYPPDCTLKGDLFVLRNFIIGTSDAAVYHLTTDGTK 597
F E +++ + + GT D+ ++ +
Sbjct: 264 ---------TDFKPITKIDLRETEQGYKGLSIRSVCWKADRLLAGTQDSEIFEVIVRERD 314
Query: 598 LEKLFVEP--KDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFEKGLGVQSL 655
L ++ + + A++ HP +PL GS +++W+ + + E+ V+S+
Sbjct: 315 KPMLILQGHCEGELWALALHPKKPLAVTGSDDRSVRLWSLADHALIARCNMEE--AVRSV 372
Query: 656 TYNPEGALLGAGFTEGTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADRSF 715
++P+G+ L G +G+ +L + K + + + FS D Y+A
Sbjct: 373 AFSPDGSQLALGMKDGSFIVLRVRDM--TEVVHIKDRKEVIHEMKFSPDGSYLAVGSNDG 430
Query: 716 TVAVYMLVVR 725
V VY + R
Sbjct: 431 PVDVYAVAQR 440
Score = 62.4 bits (150), Expect = 2e-09
Identities = 81/453 (17%), Positives = 174/453 (38%), Gaps = 50/453 (11%)
Query: 274 LLYVCAHTAIIYNVFRNNQYHLQGHANIISCLCVSEDRRWIATADKGPDCLVIIWDSFTG 333
++Y A A++YN +++Q GH + I L + + ++AT G D + +WD+ T
Sbjct: 702 VVYHIAAVAVVYNRQQHSQRLYLGHDDDILSLTIHPVKDYVATGQVGRDAAIHVWDTQTL 761
Query: 334 IPVHTIFDSCPEGNGIMAMAMTHDAKYLATISDAEVQKVCIWKWTLAVETPACTLELPTE 393
+ + G+ A+ + D K L ++ + + W W E A T +
Sbjct: 762 KCLSLL--KGQHQRGVCALDFSADGKCLVSVGLDDFHSIVFWDWKKG-EKIATTRGHKDK 818
Query: 394 YGVQNYVTFNPTNNKELVSNSKTRAIYY-----AWYEERDTLAHSAPLLTEKTFNKLVGK 448
V V NP + +LV+ ++ + +R T L T + G+
Sbjct: 819 IFV---VKCNPHHVDKLVTVGIKHIKFWQQAGGGFTSKRGTFGSVGKLETMMCVS--YGR 873
Query: 449 FSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSASTFLGFPYIKPCKLVHLQKEGITVLT 508
+F S G + +W I K V + +
Sbjct: 874 MEDLVF--------SGAATGDIFIW---------------KDILLLKTVKAHDGPVFAMY 910
Query: 509 TIDSYIVTGDIKGNIKFYDHTLSIVNWYSHLKLGAIRTLSFSKTPATPPTEKSNYPPDCT 568
+D VTG G ++ +D ++T + ++ + ++ + +
Sbjct: 911 ALDKGFVTGGKDGIVELWDDMFE----------RCLKTYAIKRSALSTSSKGLLLEDNPS 960
Query: 569 LKGDLFVLRNFIIGTSDAAVYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICG 628
++ + ++GT + + + G + + + ++ HP P+ A S
Sbjct: 961 IRAITLGHGHILVGTKNGEILEIDKSGPMTLLVQGHMEGEVWGLAAHPLLPICATVSDDK 1020
Query: 629 MIKVWNYENKQYLFSRVFEKGLGVQSLTYNPEGALLGAGFTEGTVYILDAMSLENESPEP 688
+++W + Q+ V + G + ++P+G L G +G+ +++A ++E+
Sbjct: 1021 TLRIWEL-SAQHRMLAVRKLKKGGRCCAFSPDGKALAVGLNDGSFLVVNADTVED--MVS 1077
Query: 689 FKYSRTSVTHISFSHDS-QYMATADRSFTVAVY 720
F + + ++ I FS D+ +Y+A A V +Y
Sbjct: 1078 FHHRKEMISDIKFSKDTGKYLAVASHDNFVDIY 1110
Score = 59.3 bits (142), Expect = 2e-08
Identities = 98/468 (20%), Positives = 178/468 (38%), Gaps = 76/468 (16%)
Query: 274 LLYVCAHTAIIYNVFRNNQYHLQGHANIISCLCVSEDRRW---IATADKGPDCLVIIWDS 330
+++ A I+ N+ +Q H + I CL V++ ++ +AT+ G + IWD+
Sbjct: 1389 IIFHTAAAGIVQNLSTGSQSFYLEHTDDILCLTVNQHPKYRNVVATSQIGTTPSIHIWDA 1448
Query: 331 FTGIPVHTI-FDSCPEGNGIMAMAMTHDAKYLATISDAEVQKVCIWKWTLAVETPACTLE 389
T HT+ C G+ + + K L ++ + +W+W + +
Sbjct: 1449 MTK---HTLSMLRCFHSKGVNYINFSATGKLLVSVGVDPEHTITVWRWQEGAKVASRGGH 1505
Query: 390 LPTEYGVQNYVTFNPTNNKELVSNSKTRAIYYAWYEERDTLAHSAPLLTEKTFNKLVGKF 449
L + V+ F P ++ + VS ++ TLA SA L + L
Sbjct: 1506 LERIFVVE----FRPDSDTQFVSVGVKHMKFW-------TLAGSALLYKKGVIGSLGAAK 1554
Query: 450 SQSIFHL-----NLTQILSATMEGKLVVWDIHRPPSSASTFLGFPYIKPCKLVHLQKEG- 503
Q++ + NLT + + G + VW H FL +LV G
Sbjct: 1555 MQTMLSVAFGANNLT--FTGAINGDVYVWKDH--------FL-------IRLVAKAHTGP 1597
Query: 504 -ITVLTTI-DSYIVTGDIK------GNIKFYDHTLSIVNWYSHLKLGAIRTLSFSKTPAT 555
T+ TT+ D IVTG + G +K +D + + L+ G + S
Sbjct: 1598 VFTMYTTLRDGLIVTGGKERPTKEGGAVKLWDQEMKRCRAFQ-LETGQLVECVRSV---- 1652
Query: 556 PPTEKSNYPPDCTLKGDLFVLRNFIIGTSDAAVYHLTTDGTKLEKLFVEPKDA-ICAISC 614
C KG + ++GT D + + L + I ++
Sbjct: 1653 -----------CRGKGKI------LVGTKDGEIIEVGEKNAASNILIDGHMEGEIWGLAT 1695
Query: 615 HPYQPLIAIGSICGMIKVWNYENKQYLFSRVFEKGLGVQSLTYNPEGALLGAGFTEGTVY 674
HP + L S G ++W+ +K+ L G + Y+P+G ++ G G
Sbjct: 1696 HPSKDLFISASNDGTARIWDLADKKLL--NKVSLGHAARCAAYSPDGEMVAIGMKNGEFV 1753
Query: 675 ILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADRSFTVAVYML 722
IL SL+ + + ++++ I S D++++A TV Y L
Sbjct: 1754 ILLVNSLKVWGKK--RDRKSAIQDIRISPDNRFLAVGSSEHTVDFYDL 1799
>gi|34485720 echinoderm microtubule associated protein like 5 [Homo
sapiens]
Length = 1977
Score = 67.4 bits (163), Expect = 7e-11
Identities = 84/451 (18%), Positives = 173/451 (38%), Gaps = 46/451 (10%)
Query: 274 LLYVCAHTAIIYNVFRNNQYHLQGHANIISCLCVSEDRRWIATADKGPDCLVIIWDSFTG 333
++Y A +IYN +N Q GH + I CL + + ++AT G D + IWD+ T
Sbjct: 702 IVYHVAAVGVIYNRQQNTQRFYLGHDDDILCLTIHPLKDYVATGQVGRDPSIHIWDTETI 761
Query: 334 IPVHTIFDSCPEGNGIMAMAMTHDAKYLATISDAEVQKVCIWKWTLAVETPACTLELPTE 393
P+ + G+ A+ + D K LA++ + V +W W +
Sbjct: 762 KPLSIL--KGHHQYGVSAVDFSADGKRLASVGIDDSHTVVLWDWKKGEKLSIARGSKDKI 819
Query: 394 YGVQNYVTFNPTNNKELVSNSKTRAIYYAWYEERDTLAHSAPLLTEKTFNKLVGK---FS 450
+ V NP +L+ T I + + + L+ K + +GK
Sbjct: 820 F----VVKMNPYVPDKLI----TAGIKHMKFWRK----AGGGLIGRKGYIGTLGKNDTMM 867
Query: 451 QSIFHLNLTQILSATMEGKLVVWDIHRPPSSASTFLGFPYIKPCKLVHLQKEGITVLTTI 510
+++ S T G + +W FL K V + + +
Sbjct: 868 CAVYGWTEEMAFSGTSTGDVCIW--------RDIFL-------VKTVKAHDGPVFSMHAL 912
Query: 511 DSYIVTGDIKGNIKFYDHTLSIVNWYSHLKLGAIRTLSFSKTPATPPTEKSNYPPDCTLK 570
+ VTG G + +D + ++T + + P ++ + +++
Sbjct: 913 EKGFVTGGKDGIVALWDDSFE----------RCLKTYAIKRAALAPGSKGLLLEDNPSIR 962
Query: 571 GDLFVLRNFIIGTSDAAVYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMI 630
+ ++GT + + + G + + + ++ HPY P+ A S +
Sbjct: 963 AISLGHGHILVGTKNGEILEVDKSGPITLLVQGHMEGEVWGLATHPYLPICATVSDDKTL 1022
Query: 631 KVWNYENKQYLFSRVFEKGLGVQSLTYNPEGALLGAGFTEGTVYILDAMSLENESPEPFK 690
++W+ + + V + G + ++P+G L G +G+ + +A +LE+ F
Sbjct: 1023 RIWDLSPSHCMLA-VRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADTLED--LVSFH 1079
Query: 691 YSRTSVTHISFSHDS-QYMATADRSFTVAVY 720
+ + ++ I FS S +Y+A A + +Y
Sbjct: 1080 HRKDMISDIRFSPGSGKYLAVASHDSFIDIY 1110
Score = 63.5 bits (153), Expect = 1e-09
Identities = 107/512 (20%), Positives = 194/512 (37%), Gaps = 88/512 (17%)
Query: 242 KSTPVYPLTMTWSFGWNSS---LPVYYIREERQRVLLYVCAHTAIIYNVFRNNQYHLQGH 298
K P+ L + FG+ V+Y+ + ++Y A I++NV +Q Q H
Sbjct: 1364 KKRPIEDLVLELIFGYRGRDCRNNVHYLNDGDD--IIYHTASVGILHNVATGSQSFYQEH 1421
Query: 299 ANIISCLCVSEDRRWI---ATADKGPDC-------LVIIWDSFTGIPVHTIFDSCPEGNG 348
+ I CL V++ ++I AT G + IWD+ + + C G
Sbjct: 1422 NDDILCLTVNQHPKFINIVATGQVGDSADMSATAPSIHIWDAMNKQTLSIL--RCYHSKG 1479
Query: 349 IMAMAMTHDAKYLATISDAEVQKVCIWKWTLAVETPACTLELPTEYGVQNYVT-FNPTNN 407
+ +++ + K L ++ + IW+W + + + + +V F P ++
Sbjct: 1480 VCSVSFSATGKLLLSVGLDPEHTITIWRWQEGAKIAS-----RAGHNQRIFVAEFRPDSD 1534
Query: 408 KELVSNSKTRAIYYAWYEERDTLAHSAPLLTEKTFNKLVGKFSQSIFHL-----NLTQIL 462
+ VS ++ TLA A L + + L Q++ + NLT
Sbjct: 1535 TQFVSVGVKHVKFW-------TLAGRALLSKKGLLSTLEDARMQTMLAIAFGANNLT--F 1585
Query: 463 SATMEGKLVVWDIHRPPSSASTFLGFPYIKPCKLVHLQKEG--ITVLTTI-DSYIVTGDI 519
+ T+ G + VW H C++V G + TT+ D IVTG
Sbjct: 1586 TGTISGDVCVWKDHIL---------------CRIVARAHNGPVFAMYTTLRDGLIVTGGK 1630
Query: 520 K------GNIKFYDHTLSIVNWYSHLKLGAIRTLSFSKTPATPPTEKSNYPPDCTLKGDL 573
+ G +K +D L + A R + T C KG +
Sbjct: 1631 ERPSKEGGAVKLWDQELR--------RCRAFRLETGQATDCVRSV--------CRGKGKI 1674
Query: 574 FVLRNFIIGTSDAAVYHLTTDGTKLEKLFVEPKDA-ICAISCHPYQPLIAIGSICGMIKV 632
++GT +A + + L D I ++ HP + + G +++
Sbjct: 1675 ------LVGTRNAEIIEVGEKNAACNILVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRL 1728
Query: 633 WNYENKQYLFSRVFEKGLGVQSLTYNPEGALLGAGFTEGTVYILDAMSLENESPEPFKYS 692
W+ +K+ L G +++ Y+PEG ++ G G IL SL+ + +
Sbjct: 1729 WDIADKKML--NKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKK--RDR 1784
Query: 693 RTSVTHISFSHDSQYMATADRSFTVAVYMLVV 724
R ++ I FS DS+Y+A +V Y L +
Sbjct: 1785 RCAIHDIRFSPDSRYLAVGSSENSVDFYDLTL 1816
Score = 57.8 bits (138), Expect = 6e-08
Identities = 32/136 (23%), Positives = 61/136 (44%), Gaps = 2/136 (1%)
Query: 242 KSTPVYPLTMTWSFGWNSSLPVYYIREERQRVLLYVCAHTAIIYNVFRNNQYHLQGHANI 301
+S P L + W +G+ + + ++Y A ++Y+ + Q +GH++
Sbjct: 4 RSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFYRGHSDD 63
Query: 302 ISCLCVSEDRRWIATADKGPDCLVIIWDSFTGIPVHTIFDSCPEGNGIMAMAMTHDAKYL 361
I L + +R +AT G + + IWDS+T + + D +GI +A D + L
Sbjct: 64 IISLALHPERVLVATGQVGKEPYICIWDSYTVQTISVLKD--VHTHGIACLAFDLDGQRL 121
Query: 362 ATISDAEVQKVCIWKW 377
++ VC+W W
Sbjct: 122 VSVGLDSKNAVCVWDW 137
Score = 39.7 bits (91), Expect = 0.017
Identities = 31/162 (19%), Positives = 70/162 (43%), Gaps = 7/162 (4%)
Query: 578 NFIIGTSDAAVYHLTTDGTKLEKLFVEP--KDAICAISCHPYQPLIAIGSICGMIKVWNY 635
+ ++GT D+ ++ + L ++ + + A++ HP +PL GS +++W+
Sbjct: 295 HILVGTQDSEIFEIVVQERNKPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSL 354
Query: 636 ENKQYLFSRVFEKGLGVQSLTYNPEGALLGAGFTEGTVYILDAMSLENESPEPFKYSRTS 695
+ + E+ ++ N +G L G +G+ +L + K + +
Sbjct: 355 VDHALIARCNMEE--PIRCAAVNADGIHLALGMKDGSFTVLRVRDM--TEVVHIKDRKEA 410
Query: 696 VTHISFSHDSQYMATADRSFTVAVYMLVVRNGQRVWEYLARL 737
+ + +S D Y+A +V +Y V + ++V E L L
Sbjct: 411 IHELKYSPDGTYLAVGCNDSSVDIYG-VAQRYKKVGECLGSL 451
>gi|94400919 WD repeat domain 90 [Homo sapiens]
Length = 1748
Score = 57.0 bits (136), Expect = 1e-07
Identities = 91/459 (19%), Positives = 174/459 (37%), Gaps = 57/459 (12%)
Query: 276 YVCAHTAIIYNVFRNNQYHLQGHANIISCLCVSEDRRWIATA----DKGPDCLVIIWDSF 331
Y C ++ ++ Q H GH+ IS L +S + +A+A C + +WD
Sbjct: 1135 YTCGRLVVVEDLHSGAQQHWSGHSAEISTLALSHSAQVLASASGRSSTTAHCQIRVWDVS 1194
Query: 332 TGIPVHTIFDSCPEGNGIMAMAMTHDAKYLATISDAEVQKVCIWKWTLAVETPACTLELP 391
G+ H IF P ++A+A + D + L T+ D + + + +W + L P
Sbjct: 1195 GGLCQHLIF---PHSTTVLALAFSPDDRLLVTLGDHDGRTLALWGTATYDLVSSTRLPEP 1251
Query: 392 TEYGVQNYVTFNPTNNKELVSNSKTRAIYYAWYEERDTLAHSAPLLTEKTFNKLVGKFSQ 451
+ V FNP + EL + + W ++ S + E +
Sbjct: 1252 V-----HGVAFNPWDAGELTCVGQGTVTF--WLLQQRGADISLQVRREPVPEAVGAGELT 1304
Query: 452 SIFHLNLTQILSATMEGKLVVWDIHRPPSSASTFLGFPYIKPCKLVHLQKEGITVLTTID 511
S+ + + T G++ VWD + FL + GI +L
Sbjct: 1305 SLCYGAPPLLYCGTSSGQVCVWDTR----AGRCFLSW---------EADDGGIGLLLFSG 1351
Query: 512 SYIVTGDIKGNIKFYDHTLSIVNWYSHLKLGAIRTLSFSKTPATPPTEKSNYPPDCTLKG 571
S +V+G G ++ + +GA+ L + A+ + D +
Sbjct: 1352 SRLVSGSSTGRLRLW-------------AVGAVSELRCKGSGASSVFMEHELVLDGAVVS 1398
Query: 572 DLF--VLRNFIIGTSDAAVYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGM 629
F + ++GT+ ++ ++ +L + + + P + A S G
Sbjct: 1399 ASFDDSVDMGVVGTTAGTLWFVSWAEGTSTRLISGHRSKVNEVVFSPGESHCATCSEDGS 1458
Query: 630 IKVWNYENKQYL--FSRVFEKGLGV---QSLTYNPEGALLGAGFTEGTVYILD----AMS 680
++VW + + + F + + L + PE L AG+ +G++ I AM
Sbjct: 1459 VRVWALASMELVIQFQVLNQSCLCLAWSPPCCGRPEQQRLAAGYGDGSLRIFSVSRTAME 1518
Query: 681 LENESPEPFKYSRTSVTHISFSHDSQYMATADRSFTVAV 719
L+ P P ++T ++FS D Q + + D+ VAV
Sbjct: 1519 LKMH-PHP-----VALTTVAFSTDGQTVLSGDKDGLVAV 1551
Score = 40.8 bits (94), Expect = 0.007
Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 602 FVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFEKGLGVQSLTYNPEG 661
F +DA CA++ HP +P G G ++ ++ E + L +G V LT P+G
Sbjct: 738 FTSSEDAPCAVTFHPTRPTFFCGFSSGAVRSFSLEAAEVLVEHTCHRG-AVTGLTATPDG 796
Query: 662 ALLGAGFTEGTV 673
LL + ++G++
Sbjct: 797 RLLFSSCSQGSL 808
>gi|56790932 echinoderm microtubule associated protein like 1
isoform a [Homo sapiens]
Length = 834
Score = 55.8 bits (133), Expect = 2e-07
Identities = 106/530 (20%), Positives = 190/530 (35%), Gaps = 99/530 (18%)
Query: 245 PVYPLTMTWSFGWNSSLPVYYIREERQRVLL-------YVCAHTAIIYNVFRNNQYHLQG 297
P L + W +G+ R+ R + L Y A ++YNV Q H G
Sbjct: 236 PTKRLKLEWVYGYRG-------RDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYAG 288
Query: 298 HANIISCLCVSEDRRWIATAD--------KGPDCLVIIWDSFTGIPVHTI----FDSCPE 345
H + + CL V DR IAT K V IWDS T +H I FD
Sbjct: 289 HNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVT 348
Query: 346 GNGIMAMAMTHDAKYLATISDAEVQKVCIWKWTLAVETPACTLELPTEYGVQNYVTFNPT 405
+A + ++ L + D+ + +W W + + F+PT
Sbjct: 349 ---CIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAAD----FHPT 401
Query: 406 NNKELVSNSKTRAIYYAWYEERDTLAHSAPLLTEKTFNKLV--GKFSQSIFHLNLTQILS 463
+ +V+ K+ Y W E +L L ++ K V FS++ ++
Sbjct: 402 DTNIIVTCGKSH--LYFWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSEN------GDTIT 453
Query: 464 ATMEGKLVVWDIHRPPSSASTFLGFPYIKPCKLVHLQKEGITVLTTI-DSYIVTGDIKGN 522
G ++VW + + + + + GI L + D +V+G K
Sbjct: 454 GDSSGNILVW------GKGTNRISY------AVQGAHEGGIFALCMLRDGTLVSGGGKDR 501
Query: 523 IKFYDHTLSIVNW---YSHLK-------LGAIRTLSFSKTPATPPTEKSNYPPDCTLKGD 572
+++W Y L+ G IRT++ K N+ TL GD
Sbjct: 502 --------KLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGD 553
Query: 573 LFVL-----------------RNFIIGTSD--AAVYHLTTDGTKLEKLFVEPKDAICAIS 613
+ F+ D A ++ +K+ +P +
Sbjct: 554 FTPITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQ---SSG 610
Query: 614 CHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFEKGLGVQSLTYNPEGALLGAGFTEGTV 673
HP ++A+G++ G V++ E K L + + + + Y+P+G L G + +
Sbjct: 611 FHPSGSVVAVGTLTGRWFVFDTETKD-LVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCI 669
Query: 674 YILDAMSLENESPEPFKYSRTS--VTHISFSHDSQYMATADRSFTVAVYM 721
YI + K S S +TH+ +S +SQ++ + + + ++
Sbjct: 670 YIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWV 719
>gi|56790930 echinoderm microtubule associated protein like 1
isoform b [Homo sapiens]
Length = 815
Score = 55.8 bits (133), Expect = 2e-07
Identities = 106/530 (20%), Positives = 190/530 (35%), Gaps = 99/530 (18%)
Query: 245 PVYPLTMTWSFGWNSSLPVYYIREERQRVLL-------YVCAHTAIIYNVFRNNQYHLQG 297
P L + W +G+ R+ R + L Y A ++YNV Q H G
Sbjct: 217 PTKRLKLEWVYGYRG-------RDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYAG 269
Query: 298 HANIISCLCVSEDRRWIATAD--------KGPDCLVIIWDSFTGIPVHTI----FDSCPE 345
H + + CL V DR IAT K V IWDS T +H I FD
Sbjct: 270 HNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVT 329
Query: 346 GNGIMAMAMTHDAKYLATISDAEVQKVCIWKWTLAVETPACTLELPTEYGVQNYVTFNPT 405
+A + ++ L + D+ + +W W + + F+PT
Sbjct: 330 ---CIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAAD----FHPT 382
Query: 406 NNKELVSNSKTRAIYYAWYEERDTLAHSAPLLTEKTFNKLV--GKFSQSIFHLNLTQILS 463
+ +V+ K+ Y W E +L L ++ K V FS++ ++
Sbjct: 383 DTNIIVTCGKSH--LYFWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSEN------GDTIT 434
Query: 464 ATMEGKLVVWDIHRPPSSASTFLGFPYIKPCKLVHLQKEGITVLTTI-DSYIVTGDIKGN 522
G ++VW + + + + + GI L + D +V+G K
Sbjct: 435 GDSSGNILVW------GKGTNRISY------AVQGAHEGGIFALCMLRDGTLVSGGGKDR 482
Query: 523 IKFYDHTLSIVNW---YSHLK-------LGAIRTLSFSKTPATPPTEKSNYPPDCTLKGD 572
+++W Y L+ G IRT++ K N+ TL GD
Sbjct: 483 --------KLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGD 534
Query: 573 LFVL-----------------RNFIIGTSD--AAVYHLTTDGTKLEKLFVEPKDAICAIS 613
+ F+ D A ++ +K+ +P +
Sbjct: 535 FTPITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQ---SSG 591
Query: 614 CHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFEKGLGVQSLTYNPEGALLGAGFTEGTV 673
HP ++A+G++ G V++ E K L + + + + Y+P+G L G + +
Sbjct: 592 FHPSGSVVAVGTLTGRWFVFDTETKD-LVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCI 650
Query: 674 YILDAMSLENESPEPFKYSRTS--VTHISFSHDSQYMATADRSFTVAVYM 721
YI + K S S +TH+ +S +SQ++ + + + ++
Sbjct: 651 YIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWV 700
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 55.5 bits (132), Expect = 3e-07
Identities = 60/262 (22%), Positives = 114/262 (43%), Gaps = 28/262 (10%)
Query: 20 MKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIVMEETEE 79
M+EEE K++ + ++ ++ +E +E+ R+ E+ E+E K M+E EE
Sbjct: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK------MQEQEE 54
Query: 80 KAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKSKLSLQ 139
K E +EK QEE E Q RL Q + K +R + K+ Q
Sbjct: 55 KMWEQEEKMWE--QEEKMWEQQ-------RLPEQKEKMWEQDERLREKEERMREQKMWQQ 105
Query: 140 LEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDRMPQDELGQERR 199
+E + ++ Q + ++ E++++ + + E EEK + QE +
Sbjct: 106 VEKMREKKKTQEEKMQ----EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK 161
Query: 200 DLEPENREEGQERRVSDIQSKAGISRESLV--SSTTEDI--LFQKDKSTPVYPLTMTWSF 255
E E + +GQE ++ D++ G + E + T ++I LF K+ P
Sbjct: 162 MREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQCP-----GL 216
Query: 256 GWNSSLPVYYIREERQRVLLYV 277
G S +P +Y ++R+ ++ +
Sbjct: 217 GSTSCIPFFYRGDKRKMKIINI 238
Score = 34.7 bits (78), Expect = 0.54
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQES--KDDTIAWRESQ---EEERKTGEEEGEEEGKEDKK 71
E +M+E+EE +E+ Q+E + + W + + E+E K E+E + +G+E+K
Sbjct: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
Query: 72 IVMEETEEKAGEVQEKEASGIQE 94
+E +AGE ++ QE
Sbjct: 177 RDVEPAGGEAGEGSPQDNPTAQE 199
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 55.5 bits (132), Expect = 3e-07
Identities = 63/236 (26%), Positives = 101/236 (42%), Gaps = 39/236 (16%)
Query: 11 ATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEG--KE 68
++ E E E +EEEE +E ED ++E +D+ + E +EEE + EE EEEG +E
Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEE 944
Query: 69 DKKIVMEETEEKAGEVQEKE---ASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIF 125
+++ EE EE+ EV++ E A G EE P + ++ E+
Sbjct: 945 EEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESP------------ 992
Query: 126 PKTQRGSKSK--LSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPS-GEL 182
PK Q + + L L++E+ T+E + + +PE PS GE+
Sbjct: 993 PKVQPEPEPEPGLLLEVEEPGTEE---------------ERGADTAPTLAPEALPSQGEV 1037
Query: 183 EEKTDR----MPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESLVSSTTE 234
E + + P EL +E P EE E +Q E + + TE
Sbjct: 1038 EREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETE 1093
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 55.1 bits (131), Expect = 4e-07
Identities = 51/249 (20%), Positives = 117/249 (46%), Gaps = 11/249 (4%)
Query: 1 MSDAAEAPREATGENGETE-MKEEEEPNPNYKEVEDPQQESKDDTIAWRESQ---EEERK 56
M + E RE + E E ++E+EE +++ + ++ + + WR+ + E+E K
Sbjct: 433 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 492
Query: 57 TGEEEGEEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITD 116
E+E E+ ++++KI +E + + QE+E QEE E +E+ ++ Q
Sbjct: 493 IREQE-EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEK 551
Query: 117 SQSITSGIFPKTQR--GSKSKLSLQLEDA-ETDELLRDLSTQIEFLDLDQISPEEQQISS 173
+ ++ + ++ + K+ Q E +E +R+ +I + ++ E+++++
Sbjct: 552 IRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIR--EQEEKIREQEEMTQ 609
Query: 174 PERQPSGELEEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESLVSSTT 233
+ + GE EEK + QE + E + QE+++ + + K +E ++
Sbjct: 610 EQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIR-EQEEMMQEQE 668
Query: 234 EDILFQKDK 242
E + Q++K
Sbjct: 669 EKMWEQEEK 677
Score = 41.2 bits (95), Expect = 0.006
Identities = 53/232 (22%), Positives = 103/232 (44%), Gaps = 25/232 (10%)
Query: 17 ETEMKEEEEPNPNYKEV--EDPQQESKDDTIAWRESQEEERKTGEEEGEEEGK----EDK 70
E +++E+EE +E+ E ++ + + + W E +E+ R+ E E+E K E+K
Sbjct: 388 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW-EKEEKMRRQEEMMWEKEEKIRELEEK 446
Query: 71 KIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQR 130
E+ E+ + QE+E QE+ QE A M R E +I + + + R
Sbjct: 447 MHEQEKIREQEEKRQEEEKIREQEKR----QEQEAKMWRQEEKIREQE--------EKIR 494
Query: 131 GSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDRMP 190
+ K+ Q E E +R+ + E +++ +E++I E++ +EK
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQE---QEEMWRQEEKIR--EQEEIWRQKEKIHEQE 549
Query: 191 QDELGQERRDLEPENREEGQERRVSDIQSKAGISRESLVSSTTEDILFQKDK 242
+ QE + E + QE ++ + + K +E + E I Q++K
Sbjct: 550 EKIRKQEEKMWRQEEKMHDQEEKIREQEEKVW-RQEEKIREQEEKIREQEEK 600
Score = 37.0 bits (84), Expect = 0.11
Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 11/95 (11%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGK----EDKKI 72
E +++E+EE +E Q+E + + QEE+ + EE+ E+ K +++KI
Sbjct: 598 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKI 657
Query: 73 -----VMEETEEKAGEVQEKEASGIQEETTVEPQE 102
+M+E EEK E +EK QEE E +E
Sbjct: 658 REQEEMMQEQEEKMWEQEEKMCE--QEEKMQEQEE 690
Score = 34.3 bits (77), Expect = 0.70
Identities = 49/223 (21%), Positives = 96/223 (43%), Gaps = 20/223 (8%)
Query: 22 EEEEPNPNYKEVEDPQQESKDDTIAWRE--SQEEERKTGEEEGEEEGKEDKKIVMEETEE 79
E + + V Q ++ W Q+EE+ +EE +E +E ++E EE
Sbjct: 327 EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK----IQEQEE 382
Query: 80 KAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKSKLSLQ 139
K E +EK QEE +E+ M E ++ + + ++ K ++ + + +
Sbjct: 383 KIREQEEKIRE--QEEKMRRQEEM---MWEKEEKMRRQEEM---MWEKEEKMRRQEEMMW 434
Query: 140 LEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDRMPQDELGQERR 199
++ + EL + Q + + ++ EE++I E++ E E K R + QE +
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ--EQEAKMWRQEEKIREQEEK 492
Query: 200 DLEPENREEGQERRVSDIQSKAGISRESLVSSTTEDILFQKDK 242
E E + QE ++ + Q K RE E++ Q++K
Sbjct: 493 IREQEEKMWRQEEKIHE-QEKI---REEEKRQEQEEMWRQEEK 531
Score = 30.8 bits (68), Expect = 7.7
Identities = 55/265 (20%), Positives = 112/265 (42%), Gaps = 44/265 (16%)
Query: 10 EATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKE- 68
E T G ++E++ + ++E + E++ TI Q+ E + + K+
Sbjct: 158 ETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQL 217
Query: 69 -----DKKIVMEETEEKAGEV---------QEKEASGIQEETTVEPQEVTASMIRLETQI 114
D + ++ + AGE+ Q+K+A EE T E ++ + R I
Sbjct: 218 EGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYR--NTI 275
Query: 115 TDSQSITSGIFPKTQRGSKSKLSLQLEDAETDEL---LRDLSTQIE----FLDLDQISPE 167
TD + ++ +K + LQL ++E E+ +++L ++E L Q+ E
Sbjct: 276 TDEEL--------KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAE 327
Query: 168 ------EQQISSPERQPSGELEEKTDRMPQDE----LGQERRDLEPENREEGQERRVSDI 217
E Q S + Q E E +R+ Q + QE + E E + + QE ++ +
Sbjct: 328 ADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQ 387
Query: 218 QSKAGISRESLVSSTTEDILFQKDK 242
+ K E + E+++++K++
Sbjct: 388 EEKIREQEEKM--RRQEEMMWEKEE 410
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 55.1 bits (131), Expect = 4e-07
Identities = 57/228 (25%), Positives = 99/228 (43%), Gaps = 25/228 (10%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIVMEE 76
E E + +E Y+E E QQE + RE +E+ R+ +E E + ++DKK+ +E
Sbjct: 917 EREKRRRQEQERQYREEEQLQQEEEQ---LLREEREKRRR---QERERQYRKDKKLQQKE 970
Query: 77 TEEKAGEVQEKEASGIQEETTVEPQEV---TASMIRLETQITDSQSITSGIFPKTQRGSK 133
E+ GE EK +E+ E +E+ ++R E + Q + +R +
Sbjct: 971 -EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ--------EWERQYR 1021
Query: 134 SKLSLQLED----AETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDRM 189
K LQ E+ E E R + ++ + +++ EE+Q+ ER+ E +
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR 1081
Query: 190 PQDELGQERRDL---EPENREEGQERRVSDIQSKAGISRESLVSSTTE 234
++EL QE L EPE R + R + + E L+ E
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREERE 1129
Score = 52.4 bits (124), Expect = 2e-06
Identities = 51/235 (21%), Positives = 104/235 (44%), Gaps = 28/235 (11%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEE----EGEEEGKEDKKI 72
E E + +E Y+E E+ QQE + RE +E+ R+ E + +E +E++++
Sbjct: 977 EPEKRRRQEREKKYREEEELQQEEEQ---LLREEREKRRRQEWERQYRKKDELQQEEEQL 1033
Query: 73 VMEETEEKA-----------GEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSIT 121
+ EE E++ E+Q++E + EE ++ R E ++ +
Sbjct: 1034 LREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL 1093
Query: 122 SGIFPKTQRGSKSKLSLQLEDA---ETDELLRDLSTQIEFLDLDQISPEEQQISSPERQP 178
P+ +R + + + E+ E ++LLR+ + +L++ EE+++ E Q
Sbjct: 1094 LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL 1153
Query: 179 SGELEEKTDRMP-------QDELGQERRDLEPENREEGQERRVSDIQSKAGISRE 226
E EK R ++EL QE L E +E+ ++ R + + + R+
Sbjct: 1154 LREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
Score = 52.0 bits (123), Expect = 3e-06
Identities = 57/242 (23%), Positives = 106/242 (43%), Gaps = 20/242 (8%)
Query: 14 ENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIV 73
E + ++ E++ +E QQE + + RE Q+EER+ + E+E + ++++
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERRE-QQEERREQQLRREQEERREQQLR 352
Query: 74 MEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSK 133
E+ EE+ +E++ QEE E Q +R E Q+ Q + + ++ +
Sbjct: 353 REQEEER----REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 408
Query: 134 SKLSLQLE-DAETDELLRDLSTQIEFLDLDQISPEEQQI--SSPERQPSGELEEKTDRMP 190
+ L+ E ++ LR + + EQ++ ER+ + EE+T+R
Sbjct: 409 REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468
Query: 191 QDELGQ--------ERRD----LEPENREEGQERRVSDIQSKAGISRESLVSSTTEDILF 238
Q+ Q ERR+ LE E R E QERR ++ + RE + E+
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
Query: 239 QK 240
Q+
Sbjct: 529 QQ 530
Score = 52.0 bits (123), Expect = 3e-06
Identities = 56/235 (23%), Positives = 104/235 (44%), Gaps = 21/235 (8%)
Query: 19 EMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKT------GEEEGEEEGKEDKKI 72
+++EEE+ +E Q++ +D WR EEERK + +E+ ++++++
Sbjct: 848 QLQEEEDGLQEDQERRRSQEQRRDQK--WRWQLEEERKRRRHTLYAKPALQEQLRKEQQL 905
Query: 73 VMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGS 132
+ EE EE E +EK QE E +++ E Q+ + + ++
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQE----EEQLLREEREKRRRQERERQYR 961
Query: 133 KSKLSLQLED---AETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDRM 189
K K Q E+ E E R + ++ + +++ EE+Q+ ER+ E +
Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYR 1021
Query: 190 PQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESLVSSTTEDILFQKDKST 244
+DEL QE L REE ++RR +Q + RE E+ L +++ T
Sbjct: 1022 KKDELQQEEEQL---LREEREKRR---LQERERQYREEEELQQEEEQLLGEERET 1070
Score = 50.8 bits (120), Expect = 7e-06
Identities = 50/223 (22%), Positives = 101/223 (45%), Gaps = 23/223 (10%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKD---DTIAWRESQEEERKTGEEEGEEEGKEDKKIV 73
E E + +E Y++ + QQ+ + + R QE E+K EE EE +E+++++
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE--EELQQEEEQLL 1004
Query: 74 MEETEE-----------KAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITS 122
EE E+ K E+Q++E ++EE + R E ++ +
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064
Query: 123 GIFPKTQRGSKSKLSLQLED---AETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPS 179
G +T+R + + + E+ E ++LLR+ + + ++ EE+++ E Q
Sbjct: 1065 GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLL 1124
Query: 180 GELEEKTDRMPQDELGQERRDLEPEN----REEGQERRVSDIQ 218
E EK R + +E +++ E REE ++RR +++
Sbjct: 1125 REEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELE 1167
Score = 50.1 bits (118), Expect = 1e-05
Identities = 55/235 (23%), Positives = 104/235 (44%), Gaps = 19/235 (8%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIVMEE 76
E + +E ++E E +QE++ + + QE RK EEE +E++++ +E
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQL---RRQERYRKILEEEQLRPEREEQQLRRQE 1768
Query: 77 TEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKSKL 136
+ K E E++ +EE + QE + R E Q+ + + P+ + G
Sbjct: 1769 RDRKFRE--EEQLRQEREEQQLRSQE-SDRKFREEEQLRQERE-EQQLRPQQRDGKYRWE 1824
Query: 137 SLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPE--RQPSGEL--EEKTDRMPQD 192
QL+ E ++ LR + D+ E+Q ++ E R+ EL EE+ R +
Sbjct: 1825 EEQLQLEEQEQRLRQ--------ERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQER 1876
Query: 193 ELGQERRDLEPENREEGQERRVSDIQSKAGISRESLVSSTTEDILFQKDKSTPVY 247
E + + +EE + R+V +I+S+ G L+ T +S+P+Y
Sbjct: 1877 ERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASVPVRSSPLY 1931
Score = 49.7 bits (117), Expect = 2e-05
Identities = 59/246 (23%), Positives = 106/246 (43%), Gaps = 44/246 (17%)
Query: 9 REATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQE----EERKTGEEEGEE 64
R + E E+ E EE + + +E ++ +D+ + WR+ QE EER+ EE+ +
Sbjct: 137 RRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEEL-WRQRQEWQEREERRAEEEQLQS 195
Query: 65 -EGKEDKKIVMEET--------------EEKAGEVQEKEASGIQEETTVEPQEVTASMIR 109
+G E ++ EE EEK + +E++ QEE E ++ + +
Sbjct: 196 CKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRK 255
Query: 110 LETQITDSQSITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQ 169
E ++ + + P+ QR + + QL E EL R+ EEQ
Sbjct: 256 EEEKLQEEE-------PQRQRELQEEEE-QLRKLERQELRRERQE------------EEQ 295
Query: 170 QISSPERQPSGELEEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESLV 229
Q R+ +++ +R Q E ERR+ + E RE+ +ERR ++ + RE +
Sbjct: 296 QQQRLRREQQLRRKQEEERREQQE---ERRE-QQERREQQEERREQQLRREQEERREQQL 351
Query: 230 SSTTED 235
E+
Sbjct: 352 RREQEE 357
Score = 48.5 bits (114), Expect = 4e-05
Identities = 47/227 (20%), Positives = 104/227 (45%), Gaps = 7/227 (3%)
Query: 14 ENGETEMKEEEEPNPNY----KEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKED 69
E E +K E+E ++ +E E +QE + + R+ +EE R+ + EEE +E
Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQLK-RDQEEERRERWLKLEEEERREQ 499
Query: 70 KKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQ 129
++ ++ + E +E+ +EE ++ + + +R E + Q + + +
Sbjct: 500 QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLE 559
Query: 130 RGSKSKLSLQLEDAETDELL-RDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDR 188
+ + + + ++ D+LL R+ + + L +Q EQ++ E + + E + R
Sbjct: 560 QERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQR 619
Query: 189 MPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESLVSSTTED 235
+ ++E +ERR + EE +ERR ++ + RE + E+
Sbjct: 620 LKREEPEEERRQ-QLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665
Score = 48.1 bits (113), Expect = 5e-05
Identities = 48/207 (23%), Positives = 91/207 (43%), Gaps = 10/207 (4%)
Query: 14 ENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIV 73
E + E +E++E ++ ++ +Q +++ R QE +RK EEE + +E++ +
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR 1354
Query: 74 MEETEEKAGEV----QEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQ 129
+E + K E QE+ ++EE + QE ++ E Q+ Q +
Sbjct: 1355 RQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR-CQEREQQLRQDRD 1413
Query: 130 RGSKSKLSLQLEDAETDELLRDLSTQIEFLDLD-QISPEEQQISSPERQPSGELEEKTDR 188
R + + QL E D R+ Q+ + + + EEQQ+ + E E+
Sbjct: 1414 RKFREE-EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472
Query: 189 MPQDELGQERRD---LEPENREEGQER 212
+ +L ++ RD LE E + QER
Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQER 1499
Score = 47.4 bits (111), Expect = 8e-05
Identities = 52/206 (25%), Positives = 99/206 (48%), Gaps = 24/206 (11%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKD---DTIAWRESQEEERKTGEEEGEEEGKEDKKIV 73
E E + +E Y+E E+ QQE + + R QE ER+ +E EE +E+++++
Sbjct: 1037 EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE--EELQQEEEQLL 1094
Query: 74 MEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSK 133
EE E++ QE+E +EE E Q+ ++R E + Q + +R +
Sbjct: 1095 REEPEKR--RRQERERQCREEE---ELQQEEEQLLREEREKRRRQEL--------ERQYR 1141
Query: 134 SKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDRMPQDE 193
+ +Q E+ ++LLR+ + +L++ EE+++ E Q L E+ ++ Q+
Sbjct: 1142 EEEEVQQEE---EQLLREEPEKRRRQELERQYREEEELQQEEEQ---LLREEQEKRRQER 1195
Query: 194 LGQERRDLEPENREEGQERRVSDIQS 219
Q R + E + ++ Q R D +S
Sbjct: 1196 ERQYREEEELQRQKRKQRYRDEDQRS 1221
Score = 46.6 bits (109), Expect = 1e-04
Identities = 47/205 (22%), Positives = 87/205 (42%), Gaps = 2/205 (0%)
Query: 9 REATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKE 68
RE E E + ++E +E E+ + K + R QE ++ + + EEE +E
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE 486
Query: 69 DKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKT 128
+ EE + E +E++ QEE + + RL+ ++ Q + +
Sbjct: 487 RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERR 546
Query: 129 QRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDR 188
++ K + +LE ++ L+ Q E D EE++ +R+ LE++ R
Sbjct: 547 EQLLKREEEKRLEQERREQRLK--REQEERRDQLLKREEERRQQRLKREQEERLEQRLKR 604
Query: 189 MPQDELGQERRDLEPENREEGQERR 213
+ L QE R + REE +E R
Sbjct: 605 EEVERLEQEERREQRLKREEPEEER 629
Score = 45.8 bits (107), Expect = 2e-04
Identities = 42/223 (18%), Positives = 106/223 (47%), Gaps = 30/223 (13%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIVMEE 76
E E E+EE + E+P++E + + + ++EER+ + E++ + ++++ EE
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQLL--KSEEQEERRQQQLRREQQERREQRLKREE 663
Query: 77 TEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQI--------TDSQSITSGIF--P 126
EE+ + ++E + E + +E + R++++I +++ + S ++ P
Sbjct: 664 EEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRP 723
Query: 127 KTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQP---SGELE 183
+ Q G + + E +E R +++++ + ++ ++Q+ +R+ + E
Sbjct: 724 RKQEGQRRR-------QEQEEKRRRRESELQWQEEERAHRQQQE--EEQRRDFTWQWQAE 774
Query: 184 EKTDRMPQDELG------QERRDLEPENREEGQERRVSDIQSK 220
EK++R Q Q R L E R++ ++R + + + K
Sbjct: 775 EKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEK 817
Score = 44.3 bits (103), Expect = 7e-04
Identities = 49/225 (21%), Positives = 102/225 (45%), Gaps = 12/225 (5%)
Query: 3 DAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQE--EERKTGEE 60
D E RE + E E +E++E +++ Q+E ++ + +E +E ++R E+
Sbjct: 479 DQEEERRERWLKLEEEERREQQERRE--QQLRREQEERREQRLKRQEEEERLQQRLRSEQ 536
Query: 61 EGEEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQ------EVTASMIRLETQI 114
+ E +E ++ +++ EEK E + +E +E+ Q E ++ E +
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE 596
Query: 115 TDSQSITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSP 174
Q + + ++ + + L+ E+ E + + L ++ + Q EQQ
Sbjct: 597 RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656
Query: 175 ERQPSGELEEKTDRMPQDELGQERRDLE--PENREEGQERRVSDI 217
+R E EE+ ++ + E +ERR+ E E +E+ +ER S I
Sbjct: 657 QRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701
Score = 43.1 bits (100), Expect = 0.002
Identities = 37/209 (17%), Positives = 98/209 (46%), Gaps = 5/209 (2%)
Query: 13 GENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKI 72
G+ + + +EE + E D Q E + ++ QE+ER+ EGEE+ ++ +++
Sbjct: 105 GKESLLQDRRQEEDQRRF-EPRDRQLEEEPGQRRRQKRQEQERELA--EGEEQSEKQERL 161
Query: 73 VMEETEEKAGEV-QEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRG 131
+ + + E+ ++++ +EE E +++ + + D + + + +R
Sbjct: 162 EQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRK 221
Query: 132 SKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDRMPQ 191
+ + Q + + D + ++ + + EE+++ E Q EL+E+ +++ +
Sbjct: 222 GREEKQQQRRERQ-DRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK 280
Query: 192 DELGQERRDLEPENREEGQERRVSDIQSK 220
E + RR+ + E +++ + RR ++ K
Sbjct: 281 LERQELRRERQEEEQQQQRLRREQQLRRK 309
Score = 43.1 bits (100), Expect = 0.002
Identities = 46/225 (20%), Positives = 96/225 (42%), Gaps = 13/225 (5%)
Query: 6 EAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEG--E 63
E P + + E + +EEEE +++ ++E + R+ +EEE EEE
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
Query: 64 EEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSG 123
EE ++ ++ +E + E+Q++E ++EE QE E Q + + +
Sbjct: 1156 EEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE-------RERQYREEEELQRQ 1208
Query: 124 IFPKTQRGSKSKLSLQLE-DAETDELLRDLSTQIEFLDLDQISP-EEQQISSPERQPSGE 181
+ R + L+ + + E + +RD + + +Q E+ Q+ +RQ +
Sbjct: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLR--DRQSQQD 1266
Query: 182 LEEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRE 226
L+ + + QERR + +R +E ++ + K R+
Sbjct: 1267 LQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRD 1311
Score = 42.7 bits (99), Expect = 0.002
Identities = 55/229 (24%), Positives = 92/229 (40%), Gaps = 30/229 (13%)
Query: 19 EMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIVMEETE 78
E + EEE + K E +E D+ R E R+ G EE +++ +E + V +E E
Sbjct: 185 ERRAEEEQLQSCKGHET--EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEE 242
Query: 79 EKAGEVQE----KEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKS 134
EK +E KE +QEE +E+ +L + Q + + Q+ +
Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK--LERQELRRERQEEEQQQQRL 300
Query: 135 KLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDRMPQDEL 194
+ QL + +E + E Q EQQ E+Q E EE+ ++ + E
Sbjct: 301 RREQQLRRKQEEERREQQEERRE-----QQERREQQEERREQQLRREQEERREQQLRREQ 355
Query: 195 GQERRDL-----------------EPENREEGQERRVSDIQSKAGISRE 226
+ERR+ E + R E Q RR ++ + + RE
Sbjct: 356 EEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE 404
Score = 42.7 bits (99), Expect = 0.002
Identities = 48/234 (20%), Positives = 103/234 (44%), Gaps = 23/234 (9%)
Query: 6 EAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEE- 64
E R+ ETE E+E K ++ ++ + W + +EEER+ +E E+
Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKRDQEEERRER-----WLKLEEEERREQQERREQQ 506
Query: 65 -----EGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQS 119
E + ++++ +E EE+ +Q++ S +++ E +E +++ E + Q
Sbjct: 507 LRREQEERREQRLKRQEEEER---LQQRLRS--EQQLRREQEERREQLLKREEEKRLEQE 561
Query: 120 ITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEF-LDLDQISPEEQQISSPERQP 178
+ Q + +L + E+ L R+ ++E L +++ EQ+ +R
Sbjct: 562 RREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLK 621
Query: 179 SGELEE-KTDRMPQDELGQERRDLE-----PENREEGQERRVSDIQSKAGISRE 226
E EE + ++ + E +ERR + E RE+ +R + + + + RE
Sbjct: 622 REEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675
Score = 41.2 bits (95), Expect = 0.006
Identities = 49/226 (21%), Positives = 100/226 (44%), Gaps = 27/226 (11%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIVMEE 76
E E++ +E+ +E + +++ ++ R+ +EE++ +E E++ ++D+ E
Sbjct: 1364 EEELRHQEQGRKFLEEEQRLRRQERE-----RKFLKEEQQLRCQEREQQLRQDRDRKFRE 1418
Query: 77 TEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKSKL 136
E++ QE++ +EE V QE + E Q+ + F + ++ + +
Sbjct: 1419 EEQQLSR-QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRK---FREEEQLLQERE 1474
Query: 137 SLQLEDAETDELLRDLSTQIEFLDLDQ---------------ISPEEQQISSPERQPSGE 181
QL E D + Q+ + D+ EEQQ+ +RQ
Sbjct: 1475 EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFL 1534
Query: 182 LEEKTDRMPQDELGQERR-DLEPENREEGQERRVSDIQSKAGISRE 226
EE+ ++ + E GQ+RR D + + REE Q R+ + Q + R+
Sbjct: 1535 QEEQ--QLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD 1578
Score = 39.7 bits (91), Expect = 0.017
Identities = 56/288 (19%), Positives = 123/288 (42%), Gaps = 41/288 (14%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQ----EEERKTGEEEGEEEGKEDK-- 70
E ++++E E ++ D + ++ + +E + E+E++ +EG+++ ++++
Sbjct: 1560 EEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDR 1619
Query: 71 -----KIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIR-LETQITDSQSITSGI 124
+ +++E EE+ QE++ ++EE + QE + + + + + +
Sbjct: 1620 KFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLL--- 1676
Query: 125 FPKTQRGSKSKLSLQLEDA---ETDELLRDLSTQIEFL---------DLDQISPEEQQIS 172
Q G + +L Q D E ++ LR + +FL +L++ EE+Q+
Sbjct: 1677 ----QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLR 1732
Query: 173 SPERQPSGE--------LEEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGIS 224
Q LEE+ R ++E R++ + + REE Q R+ + Q S
Sbjct: 1733 QETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLR--S 1790
Query: 225 RESLVSSTTEDILFQKDKSTPVYPLTMTWSFGWNSSLPVYYIREERQR 272
+ES E+ L Q+ + + P + W +E+R R
Sbjct: 1791 QESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR 1838
Score = 38.5 bits (88), Expect = 0.037
Identities = 45/209 (21%), Positives = 89/209 (42%), Gaps = 13/209 (6%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKE---DKKI- 72
E E + ++ + ++ E E ++E + + +EE++ EE EE+ + D+K
Sbjct: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFR 1339
Query: 73 ----VMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKT 128
+++E EE+ QE++ +EE + QE + E ++ + F K
Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFREEE--LRHQEQGRKFLEEEQRLRRQERERK--FLKE 1395
Query: 129 QRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLD-QISPEEQQISSPERQPSGELEEKTD 187
++ + + Q + D R+ Q+ + D + EEQQ+ ER+ EE+
Sbjct: 1396 EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQL 1455
Query: 188 RMPQDELGQERRDLEPENREEGQERRVSD 216
R + +E L E E+ R+ D
Sbjct: 1456 RQERHRKFREEEQLLQEREEQQLHRQERD 1484
Score = 38.1 bits (87), Expect = 0.048
Identities = 47/226 (20%), Positives = 93/226 (41%), Gaps = 21/226 (9%)
Query: 17 ETEMKEEEEPNPNYKEVEDP---QQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIV 73
E ++ +E E P ++ D ++E + + +EE+R +E + KE++++
Sbjct: 1341 EEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR 1400
Query: 74 MEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQ---- 129
+E E++ Q+++ +EE + QE E Q+ + + + Q
Sbjct: 1401 CQEREQQLR--QDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458
Query: 130 RGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDRM 189
R K + QL ++ L +FL+ EEQQ+ ER +E +
Sbjct: 1459 RHRKFREEEQLLQEREEQQLHRQERDRKFLE------EEQQLRRQERDRKFREQELRSQE 1512
Query: 190 PQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESLVSSTTED 235
P ER+ LE E + Q+R+ +Q + + R+ +D
Sbjct: 1513 P------ERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQD 1552
Score = 38.1 bits (87), Expect = 0.048
Identities = 54/233 (23%), Positives = 99/233 (42%), Gaps = 27/233 (11%)
Query: 9 REATGENGETEMKEEEEP---NPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEE 65
+E + E + EEE+ ++ +Q+ + + Q+ +RK EEE +
Sbjct: 1506 QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQ 1565
Query: 66 GKEDKKIVMEE------TEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQ---ITD 116
+E++++ +E EE+ QE+E +++E + QE +R E D
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE-GQQQLRQERDRKFRED 1624
Query: 117 SQSITSGIFPKTQRGSKSKLSL----QLEDAETDELLRDLSTQIEFLDLDQI--SPEEQQ 170
Q + + R + + L QL E ++ LR +F + +Q+ EEQQ
Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRH-DRDRKFREEEQLLQEGEEQQ 1683
Query: 171 ISSPERQPSGELEEKTDRMP-------QDELGQERRDLEPENREEGQERRVSD 216
+ ER EE+ R Q+E R++LE + REE Q R+ ++
Sbjct: 1684 LRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736
Score = 37.4 bits (85), Expect = 0.083
Identities = 47/261 (18%), Positives = 95/261 (36%), Gaps = 52/261 (19%)
Query: 10 EATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEE-------- 61
EA + + ++ ++ ++ ++ ++ + W+E + R+ EEE
Sbjct: 711 EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQ 770
Query: 62 -----------------------------GEEEGKEDKKIVMEETEEKAGEVQ----EKE 88
EE + +++ + EE E++ Q EKE
Sbjct: 771 WQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKE 830
Query: 89 ASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKSKLSLQLEDAETDEL 148
++EE ++ +E + E + + Q + +R K + L+ E
Sbjct: 831 LQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRS--QEQRRDQKWRWQLEEERKRRRHT 888
Query: 149 LRDLSTQIEFLDLDQ--ISPEEQQISSPERQPSGELEEKTDRMPQDELGQERRDLEPENR 206
L E L +Q + EE+++ ER+ E++ +++L QE L E R
Sbjct: 889 LYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREER 948
Query: 207 E-------EGQERRVSDIQSK 220
E E Q R+ +Q K
Sbjct: 949 EKRRRQERERQYRKDKKLQQK 969
Score = 36.6 bits (83), Expect = 0.14
Identities = 49/190 (25%), Positives = 86/190 (45%), Gaps = 21/190 (11%)
Query: 37 QQESKDDTIAWRESQEEERKTGEEEG--EEEGKEDKKIVMEETEEKAGEVQEKEASGIQE 94
+Q+ +D R Q+ +R EEE EE KE K+ + EEK +E+E ++
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ 1332
Query: 95 ETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKSKLSLQLED---AETDELLRD 151
ET + +E + E Q Q + ++ + +L Q + E ++ LR
Sbjct: 1333 ETDRKFREEEQLLQEREEQPLRRQE-------RDRKFREEELRHQEQGRKFLEEEQRLRR 1385
Query: 152 LSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDRMPQDELGQ-ERRDLEPENREEGQ 210
+ +FL EEQQ+ ER+ +L + DR ++E Q R++ + + REE Q
Sbjct: 1386 QERERKFL------KEEQQLRCQEREQ--QLRQDRDRKFREEEQQLSRQERDRKFREEEQ 1437
Query: 211 ERRVSDIQSK 220
+ R + + K
Sbjct: 1438 QVRRQERERK 1447
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 55.1 bits (131), Expect = 4e-07
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 4/92 (4%)
Query: 3 DAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEG 62
+ E E GE GE E +EEE E ED + E +++ W +EE GEEEG
Sbjct: 915 EEGEGKGEEEGEEGEGEGEEEEGEG----EGEDGEGEGEEEEGEWEGEEEEGEGEGEEEG 970
Query: 63 EEEGKEDKKIVMEETEEKAGEVQEKEASGIQE 94
E EG+E + EE E GE +E E G +E
Sbjct: 971 EGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEE 1002
Score = 54.7 bits (130), Expect = 5e-07
Identities = 34/97 (35%), Positives = 48/97 (49%)
Query: 6 EAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEE 65
E E GE GE E +EEE +E + + E + + E + EE + GE EGE E
Sbjct: 967 EEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVE 1026
Query: 66 GKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQE 102
G+E + EE E+ GE +EKE G + E +E
Sbjct: 1027 GEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEE 1063
Score = 51.6 bits (122), Expect = 4e-06
Identities = 69/277 (24%), Positives = 114/277 (41%), Gaps = 20/277 (7%)
Query: 3 DAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEG 62
+ E E GE GE E EE E E E+ + E +++ E +E E + GEEEG
Sbjct: 852 EEGEGKGEEEGEEGEGE--EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE-GEEEG 908
Query: 63 EEEGKEDKKIVM--EETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSI 120
E EG+E++ EE EE GE +E+E G E+ E +E E + + +
Sbjct: 909 EGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEW-EGEEEEGEGEGE 967
Query: 121 TSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSG 180
G + + + + E +E + + E + + EE++ E + G
Sbjct: 968 EEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEG 1027
Query: 181 E-----------LEEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRE-SL 228
E EE +R + E + RR+ E E EEG+ + + +++ E
Sbjct: 1028 EEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKK 1087
Query: 229 VSSTTEDILFQKDKSTPVYPLTMTWSFG--WNSSLPV 263
VS + + K K+ +T T G S +PV
Sbjct: 1088 VSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPV 1124
Score = 51.2 bits (121), Expect = 6e-06
Identities = 56/216 (25%), Positives = 88/216 (40%), Gaps = 12/216 (5%)
Query: 3 DAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEG 62
+ E E E GE E E EE +E E+ + +++ E E E + GE +G
Sbjct: 799 EETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKG 858
Query: 63 EEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITS 122
EEEG+E + EE EE GE +E+E G EE E E +
Sbjct: 859 EEEGEEGEG--EEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916
Query: 123 GIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGE- 181
G + G + + + E+ E + D + E + + EE+ E + GE
Sbjct: 917 GEGKGEEEGEEGEGEGEEEEGEGEG--EDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEG 974
Query: 182 -------LEEKTDRMPQDELGQERRDLEPENREEGQ 210
EE+ + ++E G+E + E E EEG+
Sbjct: 975 EEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGE 1010
Score = 50.4 bits (119), Expect = 9e-06
Identities = 56/214 (26%), Positives = 91/214 (42%), Gaps = 25/214 (11%)
Query: 3 DAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEG 62
D E GE GE E+ E+EE +K+ + +QE K+ ++ + +E + G EE
Sbjct: 680 DKGRGEMERPGE-GEKELAEKEE----WKKRDGEEQEQKEREQGHQKERNQEMEEGGEEE 734
Query: 63 EEEGKEDKKIVMEETEEKAGEVQE----KEASGIQEETTVEPQEVTASMIRLETQITDSQ 118
EG+E++ EE EEK GE +E +E G +E+ E + E + +
Sbjct: 735 HGEGEEEEG-DREEEEEKEGEGKEEGEGEEVEGEREKE--EGERKKEERAGKEEKGEEEG 791
Query: 119 SITSGIFPKTQ-RGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQ 177
G +T+ RG + + ++E E +E + EE++ E +
Sbjct: 792 DQGEGEEEETEGRGEEKEEGGEVEGGEVEE------------GKGEREEEEEEGEGEEEE 839
Query: 178 PSGELEEKTDRMPQDELGQERRDLEPENREEGQE 211
GE EE + E E E E EEG+E
Sbjct: 840 GEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873
Score = 50.1 bits (118), Expect = 1e-05
Identities = 55/208 (26%), Positives = 93/208 (44%), Gaps = 12/208 (5%)
Query: 14 ENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEE-GKEDKKI 72
E GE E E EE + +E E+ + E K++ E E++ GE + EE GKE+K
Sbjct: 729 EGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKG- 787
Query: 73 VMEETEEKAGEVQEKEASGIQEET--TVEPQEVTASMIRLETQITDSQSITSGIFPKTQR 130
EE ++ GE +E E G ++E VE EV E + + + + +
Sbjct: 788 -EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEE 846
Query: 131 GS------KSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEE 184
G + K + E+ E +E + + E + + EE + E + GE EE
Sbjct: 847 GEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEE 906
Query: 185 KTDRMPQDELGQERRDLEPENRE-EGQE 211
+ + ++E G+ + + E E E EG+E
Sbjct: 907 EGEGEGEEEEGEGKGEEEGEEGEGEGEE 934
Score = 42.7 bits (99), Expect = 0.002
Identities = 46/204 (22%), Positives = 89/204 (43%), Gaps = 12/204 (5%)
Query: 14 ENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIV 73
E+ + E +E+ E + E+E P + K+ E +E +++ GEE+ ++E ++ +
Sbjct: 667 EHWQDEEREKGEKDKGRGEMERPGEGEKE----LAEKEEWKKRDGEEQEQKEREQGHQKE 722
Query: 74 MEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLE---TQITDSQSITSGIFPKTQR 130
+ E+ GE E+ G +EE E +E + E ++ + G K +R
Sbjct: 723 RNQEMEEGGE--EEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEER 780
Query: 131 GSKSKLSLQLED---AETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTD 187
K + + D E +E + E +++ EE + E + GE EE+
Sbjct: 781 AGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEG 840
Query: 188 RMPQDELGQERRDLEPENREEGQE 211
++E E + E + EEG+E
Sbjct: 841 EGEEEEGEGEEEEGEGKGEEEGEE 864
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 54.7 bits (130), Expect = 5e-07
Identities = 55/218 (25%), Positives = 89/218 (40%), Gaps = 24/218 (11%)
Query: 8 PREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGK 67
P ++ G G + E E P + VE P+ E D A E+Q E E E E +
Sbjct: 1826 PGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEG-DAQEAEGEAQPESEDVEAPEAEGEAQ 1884
Query: 68 EDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPK 127
+ + V ET E EVQ + E E Q T S+ LET+ D +
Sbjct: 1885 PESEDV--ETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQE 1942
Query: 128 TQ------RGSKSKLSLQLEDAETDELLRDLSTQIEFLDLD--------QISPEEQQISS 173
+ G S +E E +E + S +E L+++ + PE + + +
Sbjct: 1943 AEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEA 2002
Query: 174 PERQPSGELEEKTDRMPQDELGQERRDLEPENREEGQE 211
PE + GE++E ++E E +E + + EG+E
Sbjct: 2003 PEAE--GEMQE-----AEEEAQPESDGVEAQPKSEGEE 2033
Score = 53.5 bits (127), Expect = 1e-06
Identities = 55/226 (24%), Positives = 106/226 (46%), Gaps = 24/226 (10%)
Query: 2 SDAAEAPR---EATGENGETEMKEEE---EPNPNYKEVEDPQQESKDDTIAWRESQEEER 55
S+ EAP EA E+ + E E E +P E + ++E++ +T ES E
Sbjct: 1871 SEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPET----ESVEALE 1926
Query: 56 KTGEEEGEEEGKEDKKIVMEETEEKAGEVQEK----EASGIQEETTVEPQEVTASMIRLE 111
GE+E E EG E ++ E +E G+ Q + E+ +EE E ++V A + +E
Sbjct: 1927 TEGEDEPESEGAEAQE-AEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVE 1985
Query: 112 TQITDSQSITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQI 171
TQ + ++ P+++ + ++++AE E + S +E + E Q++
Sbjct: 1986 TQEAEGEA-----QPESEDVEAPEAEGEMQEAE--EEAQPESDGVEAQPKSE-GEEAQEV 2037
Query: 172 SSPERQPSGELEEKTDRMPQDELGQERRDLEPENRE-EGQERRVSD 216
++ G+ + ++D + E +E ++ E E +E EG+ S+
Sbjct: 2038 EGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESE 2083
Score = 51.2 bits (121), Expect = 6e-06
Identities = 63/251 (25%), Positives = 106/251 (42%), Gaps = 39/251 (15%)
Query: 3 DAAEAPREATGENG-ETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEE 61
+A EA +EA G+ E+E+ E +E E+ Q ES+D E+ E E +T E E
Sbjct: 1942 EAEEAAQEAEGQTQPESEVIESQEAE------EEAQPESEDV-----EALEVEVETQEAE 1990
Query: 62 GEEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVT----ASMIRLETQIT-- 115
GE + + + E E GE+QE E E VE Q + A + ETQ T
Sbjct: 1991 GEAQPESEDV----EAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEG 2046
Query: 116 DSQSITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLD----QISPEEQQI 171
D+Q + G+ +++ Q + E E + + E +D + PE + +
Sbjct: 2047 DAQPESDGV-----EAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGV 2101
Query: 172 SSPERQPSGEL-------EEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGIS 224
+PE + + E + + P+ E G E + E E + E + D + +A
Sbjct: 2102 EAPEAEGEAQKAEGIEAPETEGEAQPESE-GIEAPEAEGEAQPESEGVEAQDAEGEAQPE 2160
Query: 225 RESLVSSTTED 235
E + + E+
Sbjct: 2161 SEGIEAQEAEE 2171
Score = 51.2 bits (121), Expect = 6e-06
Identities = 61/236 (25%), Positives = 99/236 (41%), Gaps = 33/236 (13%)
Query: 2 SDAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEE 61
S+ EAP EA GE E E EE +P + E + P+ E + E+QE E +T + E
Sbjct: 1997 SEDVEAP-EAEGEMQEAE--EEAQPESDGVEAQ-PKSEGE-------EAQEVEGETQKTE 2045
Query: 62 GEEEGKED---KKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQ 118
G+ + + D EE +E GEVQE E E V+ QE ++Q
Sbjct: 2046 GDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEG----------EAQ 2095
Query: 119 SITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQP 178
+ G+ G K +E ET+ + S IE +PE + + PE +
Sbjct: 2096 PESEGVEAPEAEGEAQKAE-GIEAPETEGEAQPESEGIE-------APEAEGEAQPESEG 2147
Query: 179 SGELEEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESLVSSTTE 234
+ + + P+ E G E ++ E E + E + + + +A E + + E
Sbjct: 2148 VEAQDAEGEAQPESE-GIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAE 2202
Score = 41.2 bits (95), Expect = 0.006
Identities = 50/216 (23%), Positives = 89/216 (41%), Gaps = 48/216 (22%)
Query: 11 ATGENGETEMKEEEEPNPNYKEV-------EDPQQESKDDTIAWRESQEEERKTGEEEGE 63
AT E+ EE+ + N +++ E +E+K+ T E +EE EE
Sbjct: 1270 ATNEDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEG--EGLQEEAVQLEETKT 1327
Query: 64 EEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSG 123
EEG +++ + +EET+E GE Q++E + ++E + + ++LE
Sbjct: 1328 EEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLE------------ 1375
Query: 124 IFPKTQRGSKSKLSLQ-LEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPE----RQP 178
+ + G + L + LE+ +E L PEE + E P
Sbjct: 1376 ---EVKEGPEGGLQGEALEEGLKEEGL----------------PEEGSVHGQELSEASSP 1416
Query: 179 SGELEEKTDRMPQDELGQERRDLEP---ENREEGQE 211
G+ ++ D + ++E G+ EP E EE E
Sbjct: 1417 DGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTE 1452
Score = 38.1 bits (87), Expect = 0.048
Identities = 50/234 (21%), Positives = 93/234 (39%), Gaps = 29/234 (12%)
Query: 5 AEAPREATGENGETEMKEEEEPNPNYKEVEDP----QQESK---DDTIAWRESQEEERK- 56
++ P GE+GE + + +P E E ++E K +T A E E E++
Sbjct: 1735 SQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEG 1794
Query: 57 -----TGEEEGEEEGKEDKKIVMEETEEKAGEVQEKE----ASGIQEETTVEPQEVTASM 107
GE G+ G ED + E AG Q+ A GI+ + +
Sbjct: 1795 EGISERGETGGQGSGHEDNL----QGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEG 1850
Query: 108 IRLETQITDSQSITSGIFPKTQR----GSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQ 163
+ D+Q P+++ ++ + + ED ET E ++ + E +
Sbjct: 1851 VEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAE--- 1907
Query: 164 ISPEEQQISSPERQPSGELEEKTDRMPQDELGQERRDLEPENREEGQERRVSDI 217
+PE ++ + PE + LE + + P+ E + + E EGQ + S++
Sbjct: 1908 -APEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEV 1960
Score = 36.2 bits (82), Expect = 0.18
Identities = 54/243 (22%), Positives = 96/243 (39%), Gaps = 30/243 (12%)
Query: 6 EAPREATGENGETEMKEEEEPNPNYK-EVEDPQQESKDDTIAWRESQEEERKTGE---EE 61
EA R++ + + +++ E + ++E+ ++ ++ + + Q EE KT E EE
Sbjct: 1275 EAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEE 1334
Query: 62 G---------EEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLET 112
G E EG+++++ +EE EE GE ++E G+Q E E E LE
Sbjct: 1335 GVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEE--GVQLEEVKEGPEGGLQGEALEE 1392
Query: 113 QITDSQSITSGIF---PKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISP--- 166
+ + G ++ S Q +D +E S E +
Sbjct: 1393 GLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTE 1452
Query: 167 -----EEQQISSPERQPSGELEEKTDRMP-QDELGQERRDLEPENREEGQERRVSDIQSK 220
E S+ ERQ +LE ++ P +GQE +P +G R S +
Sbjct: 1453 PPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQP---TQGAAERSSSVACS 1509
Query: 221 AGI 223
A +
Sbjct: 1510 AAL 1512
Score = 32.0 bits (71), Expect = 3.5
Identities = 44/176 (25%), Positives = 65/176 (36%), Gaps = 39/176 (22%)
Query: 2 SDAAEAPREATGE------------NGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRE 49
S+ EAP EA GE GE + + E P + P+ E + A E
Sbjct: 2098 SEGVEAP-EAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGE 2156
Query: 50 SQEEERKTGEEEGEEEGKEDKKIVME--------------ETEEKAGEVQEK----EASG 91
+Q E +E EEE + + + V E E GE Q + EA
Sbjct: 2157 AQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPE 2216
Query: 92 IQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKSKLSLQLEDAETDE 147
+EE EP+ V E Q +S+ +TQ K + L D +++E
Sbjct: 2217 AEEEAQPEPEGVETPEAEGEAQ-PESEG-------ETQGEKKGSPQVSLGDGQSEE 2264
Score = 31.2 bits (69), Expect = 5.9
Identities = 37/185 (20%), Positives = 76/185 (41%), Gaps = 27/185 (14%)
Query: 50 SQEEERKTGEEEGEEEGKED---KKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTAS 106
+Q + +T E G+ E ++ + A E E ++ + +++ +
Sbjct: 1236 NQRPDSRTYESPGDLENQQQCCFPTFLNARACACATNEDEAERDSEEQRASSNLEQLAEN 1295
Query: 107 MIRLETQITDSQSITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISP 166
++ E Q+ +++ T G G + + ++QLE+ +T+E L++ Q+E
Sbjct: 1296 TVQEEVQLEETKEGTEG------EGLQEE-AVQLEETKTEEGLQEEGVQLE--------- 1339
Query: 167 EEQQISSPERQPSGELEEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKA---GI 223
+ E + G+ EE+ +E G E E EE +E +Q +A G+
Sbjct: 1340 -----ETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGL 1394
Query: 224 SRESL 228
E L
Sbjct: 1395 KEEGL 1399
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 54.3 bits (129), Expect = 7e-07
Identities = 33/103 (32%), Positives = 59/103 (57%), Gaps = 5/103 (4%)
Query: 1 MSDAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEE 60
+S E RE E E E++EEEE +E E+ Q E +++ ++ +++E+K E
Sbjct: 2243 LSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEE---KKKKKKEKKKEEV 2299
Query: 61 EGEEEGKEDKKIVM--EETEEKAGEVQEKEASGIQEETTVEPQ 101
+ +EE E+K+ +M EETE + E +E+E+ ++EE E +
Sbjct: 2300 QEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKE 2342
Score = 47.4 bits (111), Expect = 8e-05
Identities = 27/93 (29%), Positives = 47/93 (50%)
Query: 3 DAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEG 62
D E + E E +EEE +E E+ ++E ++ E +EEE+K ++E
Sbjct: 2235 DELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEK 2294
Query: 63 EEEGKEDKKIVMEETEEKAGEVQEKEASGIQEE 95
++E ++K+ V EE EE E + + S +EE
Sbjct: 2295 KKEEVQEKEEVFEEKEEIMSEEETESLSDEEEE 2327
Score = 47.0 bits (110), Expect = 1e-04
Identities = 33/107 (30%), Positives = 53/107 (49%), Gaps = 8/107 (7%)
Query: 15 NGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIVM 74
+ E E + EEE +EV + ++E K E +E E K E+E EE+ K+ K+
Sbjct: 2244 SSEEEEEREEEEEREEEEVREEEEERK-------EEEEGEEKQVEKEEEEKKKKKKEKKK 2296
Query: 75 EETEEKAGEVQEKEASGIQEET-TVEPQEVTASMIRLETQITDSQSI 120
EE +EK +EKE +EET ++ +E LE ++ + I
Sbjct: 2297 EEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEI 2343
Score = 45.1 bits (105), Expect = 4e-04
Identities = 25/89 (28%), Positives = 53/89 (59%), Gaps = 3/89 (3%)
Query: 19 EMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIVMEETE 78
E++++E + +E + ++E +++ + E + +E + GEE+ E+ +E+KK ++ E
Sbjct: 2236 ELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKK--KKKKE 2293
Query: 79 EKAGEVQEKEASGIQEETTVEPQEVTASM 107
+K EVQEKE +E+ + +E T S+
Sbjct: 2294 KKKEEVQEKE-EVFEEKEEIMSEEETESL 2321
Score = 42.7 bits (99), Expect = 0.002
Identities = 52/229 (22%), Positives = 111/229 (48%), Gaps = 40/229 (17%)
Query: 38 QESKDDTIAWRESQE------EERKTGEEEGEEEGKEDKKIVMEE--TEEKAGEVQEKEA 89
++SK D W S++ +E+K ++ + K + I EE TEE++ ++ K +
Sbjct: 2114 EQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEES-KLARKHS 2172
Query: 90 SGI---QEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSK--SKLSLQLEDAE 144
I +EE +E +EV + R + +++ RG K K S Q+++ E
Sbjct: 2173 EVILDDEEEGGIEEEEVIPFLKRRWRKRKEAK-----------RGDKPKEKFSSQVDEVE 2221
Query: 145 TDELLRDLSTQIEFLDLDQI-------SPEEQQISSPERQPSGELEEKTDRMPQDELGQE 197
++E S ++E L LD++ S EE++ E + E+ E+ + ++E G+E
Sbjct: 2222 SEE---HFSEEMESL-LDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEE 2277
Query: 198 RR--DLEPENREEGQERRVSDIQSKAGI--SRESLVSSTTEDILFQKDK 242
++ E E +++ +E++ ++Q K + +E ++S + L +++
Sbjct: 2278 KQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEE 2326
Score = 41.2 bits (95), Expect = 0.006
Identities = 28/92 (30%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Query: 14 ENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIV 73
E+ E +E E ++ E E +++ E +EEE + EEE +EE + ++K V
Sbjct: 2221 ESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQV 2280
Query: 74 MEETEEKAGEVQEKEASGIQEETTV--EPQEV 103
+E EEK + +EK+ +QE+ V E +E+
Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEI 2312
Score = 38.9 bits (89), Expect = 0.028
Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 11/96 (11%)
Query: 6 EAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRE---SQEEERKTGEEEG 62
E E GE + E KEEEE KE + + + K++ +E S+EE +EE
Sbjct: 2268 ERKEEEEGEEKQVE-KEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEE 2326
Query: 63 EEEG-------KEDKKIVMEETEEKAGEVQEKEASG 91
EEE +K+I+ +E + K E + K G
Sbjct: 2327 EEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRG 2362
Score = 36.6 bits (83), Expect = 0.14
Identities = 39/166 (23%), Positives = 73/166 (43%), Gaps = 33/166 (19%)
Query: 21 KEEEEPNPNYKEVEDPQQESKD-----DTIAWRES----QEEERKTGEEEGEEEGKEDKK 71
K +E+ + EVE + S++ D + +ES +EEER+ EE EEE +E+++
Sbjct: 2208 KPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEE 2267
Query: 72 IVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRG 131
E EE+ GE EK+ +EE + +E ++ + ++ + +
Sbjct: 2268 ---ERKEEEEGE--EKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKE------------ 2310
Query: 132 SKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQ 177
++ E E L D + E L++ E++I E+Q
Sbjct: 2311 -------EIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQ 2349
Score = 36.2 bits (82), Expect = 0.18
Identities = 63/289 (21%), Positives = 121/289 (41%), Gaps = 46/289 (15%)
Query: 1 MSDAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTI----AWRESQEE--- 53
+ + A + + G+ M E ++K+ D ++ +T AW+E E+
Sbjct: 1431 VEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLL 1490
Query: 54 ----------ERKTGEEEGEEEGKEDKKIVMEETEE--------KAGEVQEKEASGIQEE 95
E+ + EEE + EDKK+ EE ++ K+ E Q K+ +EE
Sbjct: 1491 QEEEKLHQAGEKLSPEEEMLQ---EDKKLKWEEWKQVWENMLSSKSKEQQYKD----EEE 1543
Query: 96 TTVEPQEVTASMIRLETQITDSQSIT------SGIFPKTQRGSKSKLSLQLEDAETDELL 149
T+E +EV+ E Q+T+ Q + I K R K + + + A+ +E L
Sbjct: 1544 VTLE-EEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKL 1602
Query: 150 RDLSTQI--EFLDLDQISPEEQQISSPERQPSGELEEKTDRMPQ--DELGQERRDLEPEN 205
Q+ E L Q + Q Q G+ +K + + Q ++L QE L +
Sbjct: 1603 AQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKR 1662
Query: 206 REEGQE-RRVSDIQSKAGISRESLVSSTTEDILFQKDKSTPVYPLTMTW 253
++ ++ +V+ + K ++++ + ++IL QK + P + W
Sbjct: 1663 KKLAKKWEKVAREEEK--LAKKGGKLAEVKNILAQKVEELPQREQNLDW 1709
Score = 34.3 bits (77), Expect = 0.70
Identities = 45/230 (19%), Positives = 91/230 (39%), Gaps = 32/230 (13%)
Query: 35 DPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIVMEETEEKAGEVQEKEASGIQE 94
D +E + ES+E + E +E K++ EE E + E +E+E +E
Sbjct: 2207 DKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEE 2266
Query: 95 ETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLST 154
E E +E + E + ++ K K + E E +E+ +
Sbjct: 2267 EERKEEEEGEEKQVEKEEE---------------EKKKKKKEKKKEEVQEKEEVFEEKEE 2311
Query: 155 QIEFLDLDQISPEEQQISSPERQPSGELEEKTDRMPQDELGQERRDLEPENRE--EGQER 212
+ + + +S EE E + S LEE+ DR + +++ L+ + R+ G+ER
Sbjct: 2312 IMSEEETESLSDEE------EEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRER 2365
Query: 213 RVSDIQS---------KAGISRESLVSSTTEDILFQKDKSTPVYPLTMTW 253
+S ++ + G+ + L + + ++ PV ++W
Sbjct: 2366 VLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVPVPEKQISW 2415
Score = 33.9 bits (76), Expect = 0.91
Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 7/92 (7%)
Query: 3 DAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQ-ESKDDTIAWRESQ--EEERKTGE 59
+ A+ E + E KEEE K VE+ ++ +++ +AW+ + EEE K +
Sbjct: 1713 ELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQ 1772
Query: 60 EE----GEEEGKEDKKIVMEETEEKAGEVQEK 87
EE E+E K M E EE+ G +E+
Sbjct: 1773 EEELLIQEKEKLAQHKEKMPEEEERLGRKREQ 1804
Score = 33.1 bits (74), Expect = 1.6
Identities = 43/239 (17%), Positives = 102/239 (42%), Gaps = 25/239 (10%)
Query: 16 GETEM-KEEEEPNPNYKEVEDPQQESKD--DTIAWRESQEEERKTGEEEGEEEG------ 66
GE ++ KEE+ N K + + + + +T++ E+ E R+ + E+E
Sbjct: 1952 GELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLS 2011
Query: 67 -------KEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQS 119
ED+ + MEE+E G+++ I + + + + +I+ ++ +
Sbjct: 2012 LEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPA 2071
Query: 120 ITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPS 179
+ I Q+ ++ + L E+ + ++ R L + L ++Q + ++ E++
Sbjct: 2072 KLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSE 2131
Query: 180 GELEEKTDRMPQDELGQE-RRDLEPENREEGQERRVS--------DIQSKAGISRESLV 229
+EK Q +L + RR + E + +E +++ D + + GI E ++
Sbjct: 2132 LTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVI 2190
Score = 32.0 bits (71), Expect = 3.5
Identities = 37/162 (22%), Positives = 67/162 (41%), Gaps = 15/162 (9%)
Query: 14 ENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEE-EGKEDKKI 72
E +++ E E +E+E E + E +EE + E E EE +E+++
Sbjct: 2211 EKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERK 2270
Query: 73 VMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGS 132
EE EEK E +E+E ++E E + + + +I + S
Sbjct: 2271 EEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETES---------- 2320
Query: 133 KSKLSLQLEDAETDELLRDLSTQIEFLDLD-QISPEEQQISS 173
LS + E+ E+ L ++ + E L + Q +EQ+ S
Sbjct: 2321 ---LSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKS 2359
>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
Length = 558
Score = 52.8 bits (125), Expect = 2e-06
Identities = 49/237 (20%), Positives = 105/237 (44%), Gaps = 32/237 (13%)
Query: 12 TGENGETEMKEEEEPNPNYKEVEDPQQESKD-DTIAWRESQEEERKTGEEEGEEEGKEDK 70
T EN TE +E+ E E+E+ + +K WR+++E +++ E+E EEE K +
Sbjct: 135 TAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 194
Query: 71 KIVME-ETEEKAGEVQEKEASGIQEETTV--------------EPQEVTASMIRLETQIT 115
+ E + EEK +VQ K +++ T EP+E S + + T
Sbjct: 195 GSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFT 254
Query: 116 DSQSITSGIFPKTQRGSKSKLSL----------------QLEDAETDELLRDLSTQIEFL 159
+ +S + +++ S Q+E + E LR + E
Sbjct: 255 EVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESE 314
Query: 160 DLDQISPEEQQISSPERQPSGELEEKTDRMPQDELGQERRDLEPENREEGQERRVSD 216
+ +++ ++Q+ + + + EE+ + ++E +++ + + + REE ++RR+ +
Sbjct: 315 EFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKE 371
Score = 36.6 bits (83), Expect = 0.14
Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 9/102 (8%)
Query: 3 DAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEG 62
+A + E GETE +E +++++ QQE+ + ++ +EE RK EEE
Sbjct: 296 EAGKRLEELRRRRGETESEE-------FEKLKQKQQEAALELEELKKKREERRKVLEEEE 348
Query: 63 EEEGKE--DKKIVMEETEEKAGEVQEKEASGIQEETTVEPQE 102
+ +E D+K+ EE + + E E+ + E+ P++
Sbjct: 349 QRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPED 390
>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
Length = 564
Score = 52.8 bits (125), Expect = 2e-06
Identities = 49/237 (20%), Positives = 105/237 (44%), Gaps = 32/237 (13%)
Query: 12 TGENGETEMKEEEEPNPNYKEVEDPQQESKD-DTIAWRESQEEERKTGEEEGEEEGKEDK 70
T EN TE +E+ E E+E+ + +K WR+++E +++ E+E EEE K +
Sbjct: 141 TAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 200
Query: 71 KIVME-ETEEKAGEVQEKEASGIQEETTV--------------EPQEVTASMIRLETQIT 115
+ E + EEK +VQ K +++ T EP+E S + + T
Sbjct: 201 GSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFT 260
Query: 116 DSQSITSGIFPKTQRGSKSKLSL----------------QLEDAETDELLRDLSTQIEFL 159
+ +S + +++ S Q+E + E LR + E
Sbjct: 261 EVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESE 320
Query: 160 DLDQISPEEQQISSPERQPSGELEEKTDRMPQDELGQERRDLEPENREEGQERRVSD 216
+ +++ ++Q+ + + + EE+ + ++E +++ + + + REE ++RR+ +
Sbjct: 321 EFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKE 377
Score = 36.6 bits (83), Expect = 0.14
Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 9/102 (8%)
Query: 3 DAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEG 62
+A + E GETE +E +++++ QQE+ + ++ +EE RK EEE
Sbjct: 302 EAGKRLEELRRRRGETESEE-------FEKLKQKQQEAALELEELKKKREERRKVLEEEE 354
Query: 63 EEEGKE--DKKIVMEETEEKAGEVQEKEASGIQEETTVEPQE 102
+ +E D+K+ EE + + E E+ + E+ P++
Sbjct: 355 QRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPED 396
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 52.8 bits (125), Expect = 2e-06
Identities = 54/230 (23%), Positives = 103/230 (44%), Gaps = 24/230 (10%)
Query: 12 TGENGETEMKEEEEPNPNYKEVEDPQQESKD-DTIAWRESQEEERKTGEEEGEEEGKEDK 70
T EN TE +E+ E E+E+ + +K WR+++E +++ E+E EEE K +
Sbjct: 141 TAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 200
Query: 71 KIVMEE-----TEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIF 125
+ E EEK E QE+ + + +E E + S I+
Sbjct: 201 GSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQE----EEREQGSDEISH--H 254
Query: 126 PKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELE-- 183
K + K + + E +E R + Q + +I+ E +I + E+ + E E
Sbjct: 255 EKMEEEDKERAEAERARLEAEERERIKAEQDK-----KIADERARIEAEEKAAAQERERR 309
Query: 184 --EKTDRMPQDE--LGQERRDLEPENREEGQER-RVSDIQSKAGISRESL 228
E+ +RM ++E +ER+ ++ E + +ER R+ + + +A R+ +
Sbjct: 310 EAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRI 359
Score = 45.4 bits (106), Expect = 3e-04
Identities = 56/265 (21%), Positives = 106/265 (40%), Gaps = 33/265 (12%)
Query: 2 SDAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEE 61
++ E RE E + +EE +E + ++E K + +EEE++ EE
Sbjct: 311 AEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 370
Query: 62 GEEEGKEDKKIVMEET------EEKAGEVQEKEASGIQEETTVEPQ---EVTASMIRLET 112
+E++K +EE EEK +QE + G + E +E + E A +L+T
Sbjct: 371 QRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQT 430
Query: 113 QITDSQSITSG--IFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIE---FLD------- 160
+ Q G + K ++ + K + + E+ + +++ +D + E F+D
Sbjct: 431 AVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTE 490
Query: 161 ---------LDQISPEEQQISSPERQPSGELEEKTDRMPQDELGQERRDLEPENREEGQE 211
++ E S P + S + +E + PQ E G+ +L E E
Sbjct: 491 VKSQNGEFMTHKLKHTENTFSRPGGRASVDTKE-AEGAPQVEAGKRLEELRRRRGETESE 549
Query: 212 --RRVSDIQSKAGISRESLVSSTTE 234
++ Q +A + E L E
Sbjct: 550 EFEKLKQKQQEAALELEELKKKREE 574
Score = 44.7 bits (104), Expect = 5e-04
Identities = 48/246 (19%), Positives = 106/246 (43%), Gaps = 38/246 (15%)
Query: 4 AAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGE 63
AAE + A E E EE++ N +E + QE+K + + E++ G+ E
Sbjct: 366 AAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKI-----KGEKVEQKIEGKWVNE 420
Query: 64 EEGKEDK---KIVMEETEEKAGEVQEKEASGIQEETTV--------------EPQEVTAS 106
++ +EDK ++ ++ EEK +VQ K +++ T EP+E S
Sbjct: 421 KKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKS 480
Query: 107 MIRLETQITDSQSITSGIFPKTQRGSKSKLSL----------------QLEDAETDELLR 150
+ + T+ +S + +++ S Q+E + E LR
Sbjct: 481 FMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELR 540
Query: 151 DLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDRMPQDELGQERRDLEPENREEGQ 210
+ E + +++ ++Q+ + + + EE+ + ++E +++ + + + REE +
Sbjct: 541 RRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEE 600
Query: 211 ERRVSD 216
+RR+ +
Sbjct: 601 KRRLKE 606
Score = 37.0 bits (84), Expect = 0.11
Identities = 45/198 (22%), Positives = 87/198 (43%), Gaps = 27/198 (13%)
Query: 4 AAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQ---EEERKTGEE 60
AA RE M+EEE+ + E+ Q+ +++ A E Q EEE++ EE
Sbjct: 301 AAAQERERREAEERERMREEEK-----RAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE 355
Query: 61 EGEEEGKEDKKIVMEE------TEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQI 114
+ KE++K EE EE+ +V+E++ + EE QE ++E +I
Sbjct: 356 R--QRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKI 413
Query: 115 TDSQSITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQIS-- 172
G + ++ + KL + + +E + + E L D+ + ++++I
Sbjct: 414 -------EGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDE 466
Query: 173 --SPERQPSGELEEKTDR 188
+++P E++ DR
Sbjct: 467 KIKKDKEPKEEVKSFMDR 484
Score = 36.6 bits (83), Expect = 0.14
Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 9/102 (8%)
Query: 3 DAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEG 62
+A + E GETE +E +++++ QQE+ + ++ +EE RK EEE
Sbjct: 531 EAGKRLEELRRRRGETESEE-------FEKLKQKQQEAALELEELKKKREERRKVLEEEE 583
Query: 63 EEEGKE--DKKIVMEETEEKAGEVQEKEASGIQEETTVEPQE 102
+ +E D+K+ EE + + E E+ + E+ P++
Sbjct: 584 QRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPED 625
Score = 34.3 bits (77), Expect = 0.70
Identities = 39/218 (17%), Positives = 95/218 (43%), Gaps = 16/218 (7%)
Query: 6 EAPREATGENGETEMKEEEEPNPNY-KEVEDPQQ--ESKDDTIAW----RESQEEERKTG 58
E A E E +E E K++ D + E+++ A RE++E ER
Sbjct: 260 EDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMRE 319
Query: 59 EEEGEEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQ 118
EE+ E ++ K + E+ ++E+E +E ++ +E A+ R + + +
Sbjct: 320 EEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEE 379
Query: 119 SITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQP 178
+ ++ + K ++Q ET + +IE +++ +E ++ + +
Sbjct: 380 KAKVEEQKRNKQLEEKKHAMQ----ETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKK 435
Query: 179 SGE-----LEEKTDRMPQDELGQERRDLEPENREEGQE 211
GE ++ K +++ +D+ ++ +++ E ++ +E
Sbjct: 436 QGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKE 473
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 51.2 bits (121), Expect = 6e-06
Identities = 46/210 (21%), Positives = 104/210 (49%), Gaps = 26/210 (12%)
Query: 9 REATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGE----E 64
+E + E +M+++EE +E E+ +E ++ + +E E+E +TGE+E + E
Sbjct: 246 QEEQVQKQEEQMRKQEE---QMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQE 302
Query: 65 EGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGI 124
E +++ M E EE+ E ++E G QEE E +E M + Q+ +
Sbjct: 303 EQMREQEEQMREQEEQMRE--QEEQMGKQEEQMWEQKE---QMWEQKEQMWKQEE----- 352
Query: 125 FPKTQRGSKSKLSLQLED--AETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGEL 182
Q G + + + E+ + +E +R Q+ + +Q+ +E+Q+ +++ GE
Sbjct: 353 ----QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQE-EQMRKQEEQMGE-QKEQMGEQ 406
Query: 183 EEKTDRMPQDELGQERRDLEPENREEGQER 212
+E+ R ++++G+++ + + G+++
Sbjct: 407 KEQM-REQEEQMGEQKEQMRKQEEHMGEQK 435
Score = 49.7 bits (117), Expect = 2e-05
Identities = 36/205 (17%), Positives = 98/205 (47%), Gaps = 5/205 (2%)
Query: 10 EATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKED 69
E GE E K+EE+ ++V+ +++ + R+ +E+ R+ E+ E+E +
Sbjct: 220 EQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQML 279
Query: 70 KKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQ 129
K+ E EE+ GE QE++ +E+ + +++ ++ Q ++ + +
Sbjct: 280 KQKEQTEQEEQTGE-QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKE 338
Query: 130 RGSKSKLSLQLEDAETDELLRDLSTQIEFL--DLDQISPEEQQISSPERQPSGELEEKTD 187
+ + K + ++ + E + Q E + +Q+ +E+Q+ E Q + E+ +
Sbjct: 339 QMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE 398
Query: 188 RMPQDELGQERRDLEPENREEGQER 212
+ ++++G+++ + + + G+++
Sbjct: 399 Q--KEQMGEQKEQMREQEEQMGEQK 421
Score = 47.4 bits (111), Expect = 8e-05
Identities = 53/228 (23%), Positives = 99/228 (43%), Gaps = 20/228 (8%)
Query: 9 REATGENGETE--MKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEG 66
RE G+ GE E M E+EE +E Q+E + QEE+ E+ E+
Sbjct: 188 REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMG---EQEEQVQ 244
Query: 67 KEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFP 126
K+++++ +E + + E Q +E QEE E +E M++ + Q Q +G
Sbjct: 245 KQEEQVQKQEEQMRKQEEQMRE----QEEQMREQEE---QMLKQKEQ--TEQEEQTGEQE 295
Query: 127 KTQRGSKSKLSLQLED-AETDELLRDLSTQIEFLDLDQISPEEQQISSPER-----QPSG 180
+ R + ++ Q E E +E +R+ Q+ + +EQ E+ + G
Sbjct: 296 EQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG 355
Query: 181 ELEEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESL 228
E EE+ + + QE + + E + QE ++ + + G +E +
Sbjct: 356 EQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQM 403
Score = 45.4 bits (106), Expect = 3e-04
Identities = 43/238 (18%), Positives = 110/238 (46%), Gaps = 20/238 (8%)
Query: 10 EATGENGETEMKEEEEPNPNYKEV--EDPQQESKDDTIAWRESQEEERKTGEEEGEEEGK 67
E GE E K+EE+ +++ ++ Q +++ + +E Q ++++ + EE+ +
Sbjct: 206 EQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMR 265
Query: 68 EDKKIVMEETEE---KAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGI 124
E ++ + E+ E+ + + +++E +G QEE E +E M E Q+ + +
Sbjct: 266 EQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEE---QMREQEEQMREQE------ 316
Query: 125 FPKTQRGSKSKLSLQLEDA-ETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELE 183
+ R + ++ Q E E E + + Q+ + +Q+ +E+Q+ E Q +
Sbjct: 317 --EQMREQEEQMGKQEEQMWEQKEQMWEQKEQM-WKQEEQMGEQEEQMQKQEEQV--RKQ 371
Query: 184 EKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESLVSSTTEDILFQKD 241
E+ R ++++ ++ + + + G+++ Q + +E + E + Q++
Sbjct: 372 EEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
Score = 42.4 bits (98), Expect = 0.003
Identities = 49/220 (22%), Positives = 94/220 (42%), Gaps = 25/220 (11%)
Query: 9 REATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKE 68
RE G+ E E + E+ +V + + + ++ RE + + R+ + GE+EG+
Sbjct: 146 REQEGQVREQEGQVREQEG----QVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQ- 200
Query: 69 DKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKT 128
M E EE+ GE +E+ QEE E +E M + E Q+ + + +
Sbjct: 201 -----MGEQEEQMGEQEEQMQK--QEEQMGEQEE---QMRKQEEQMGEQEEQVQKQEEQV 250
Query: 129 QRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDR 188
Q+ + + + E +E +R+ Q+ L Q EQ+ + +GE EE+
Sbjct: 251 QKQEEQMRKQEEQMREQEEQMREQEEQM----LKQKEQTEQE------EQTGEQEEQMRE 300
Query: 189 MPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESL 228
+ QE + E E + QE ++ + + +E +
Sbjct: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340
Score = 35.8 bits (81), Expect = 0.24
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKE--DKKIVM 74
E +M E+EE +E Q+E QEE+ + EE+ E+ ++ ++K M
Sbjct: 351 EEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQM 410
Query: 75 EETEEKAGEVQEKEASGIQEETTVEPQE 102
E EE+ GE +KE QEE E +E
Sbjct: 411 REQEEQMGE--QKEQMRKQEEHMGEQKE 436
Score = 32.3 bits (72), Expect = 2.7
Identities = 41/192 (21%), Positives = 89/192 (46%), Gaps = 17/192 (8%)
Query: 26 PNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIVMEETE--EKAGE 83
P +E+++ E +++ + E+++ E + +E + + + DK + +E + E+ G+
Sbjct: 2 PRITNEELKEKNAELQEE-LQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQ 60
Query: 84 VQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKSKLSLQLEDA 143
V+E+E ++E V QE + E Q+ + + + Q G + Q+ +
Sbjct: 61 VREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQV-----REQEGQVREQEGQVREQ 113
Query: 144 ETDELLRDLSTQIEFLDLDQISPEEQQISSPE---RQPSGELEEKTDRMPQDELGQERRD 200
E +R+ Q+ + Q+ +E Q+ E R+ G++ E+ ++ + E GQ R
Sbjct: 114 EGQ--VREQEGQVREQE-GQVREQEGQVREQEGQVREQEGQVREQEGQVREQE-GQVREQ 169
Query: 201 LEPENREEGQER 212
+EGQ R
Sbjct: 170 EGQVREQEGQVR 181
>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
Length = 532
Score = 50.4 bits (119), Expect = 9e-06
Identities = 44/222 (19%), Positives = 97/222 (43%), Gaps = 28/222 (12%)
Query: 12 TGENGETEMKEEEEPNPNYKEVEDPQQESKD-DTIAWRESQEEERKTGEEEGEEEGKEDK 70
T EN TE +E+ E E+E+ + +K WR+++E +++ E+E EEE K
Sbjct: 135 TAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKP-- 192
Query: 71 KIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQR 130
K G + E + + + EP+E S + + T+ +S +
Sbjct: 193 ---------KRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLK 243
Query: 131 GSKSKLSL----------------QLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSP 174
+++ S Q+E + E LR + E + +++ ++Q+ +
Sbjct: 244 HTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALE 303
Query: 175 ERQPSGELEEKTDRMPQDELGQERRDLEPENREEGQERRVSD 216
+ + EE+ + ++E +++ + + + REE ++RR+ +
Sbjct: 304 LEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKE 345
Score = 36.6 bits (83), Expect = 0.14
Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 9/102 (8%)
Query: 3 DAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEG 62
+A + E GETE +E +++++ QQE+ + ++ +EE RK EEE
Sbjct: 270 EAGKRLEELRRRRGETESEE-------FEKLKQKQQEAALELEELKKKREERRKVLEEEE 322
Query: 63 EEEGKE--DKKIVMEETEEKAGEVQEKEASGIQEETTVEPQE 102
+ +E D+K+ EE + + E E+ + E+ P++
Sbjct: 323 QRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPED 364
>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
Length = 538
Score = 50.4 bits (119), Expect = 9e-06
Identities = 44/222 (19%), Positives = 97/222 (43%), Gaps = 28/222 (12%)
Query: 12 TGENGETEMKEEEEPNPNYKEVEDPQQESKD-DTIAWRESQEEERKTGEEEGEEEGKEDK 70
T EN TE +E+ E E+E+ + +K WR+++E +++ E+E EEE K
Sbjct: 141 TAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKP-- 198
Query: 71 KIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQR 130
K G + E + + + EP+E S + + T+ +S +
Sbjct: 199 ---------KRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLK 249
Query: 131 GSKSKLSL----------------QLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSP 174
+++ S Q+E + E LR + E + +++ ++Q+ +
Sbjct: 250 HTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALE 309
Query: 175 ERQPSGELEEKTDRMPQDELGQERRDLEPENREEGQERRVSD 216
+ + EE+ + ++E +++ + + + REE ++RR+ +
Sbjct: 310 LEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKE 351
Score = 36.6 bits (83), Expect = 0.14
Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 9/102 (8%)
Query: 3 DAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEG 62
+A + E GETE +E +++++ QQE+ + ++ +EE RK EEE
Sbjct: 276 EAGKRLEELRRRRGETESEE-------FEKLKQKQQEAALELEELKKKREERRKVLEEEE 328
Query: 63 EEEGKE--DKKIVMEETEEKAGEVQEKEASGIQEETTVEPQE 102
+ +E D+K+ EE + + E E+ + E+ P++
Sbjct: 329 QRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPED 370
>gi|110227615 echinoderm microtubule associated protein like 3 [Homo
sapiens]
Length = 896
Score = 50.4 bits (119), Expect = 9e-06
Identities = 53/257 (20%), Positives = 97/257 (37%), Gaps = 23/257 (8%)
Query: 245 PVYPLTMTWSFGWNSSLPVYYIREERQRVLLYVCAHTAIIYNVFRN-------NQYHLQG 297
P L++ W +G+ + R ++Y A ++Y Q H +G
Sbjct: 244 PPETLSLDWVYGYRGRDSRSNLFVLRSGEVVYFIACVVVLYRPGGGPGGPGGGGQRHYRG 303
Query: 298 HANIISCLCVSEDRRWIATAD--------KGPDCLVIIWDSFTGIPVHTI-FDSCPEGNG 348
H + + CL V D +A+ K +V IWDS T + + I + G G
Sbjct: 304 HTDCVRCLAVHPDGVRVASGQTAGVDKDGKPLQPVVHIWDSETLLKLQEIGLGAFERGVG 363
Query: 349 IMAMAMTHDAKYLATISDAEVQKVCIWKWTLAVETPACTLELPTEYGVQNYVTFNPTNNK 408
+A + +L + D+ + +W + ++ E+ + V FNP ++
Sbjct: 364 ALAFSAADQGAFLCVVDDSNEHMLSVWDCSRGMK----LAEIKSTNDSVLAVGFNPRDSS 419
Query: 409 ELVSNSKTRAIYYAWYEERDTLAHSAPLLTEKTFNKL-VGKFSQSIFHLNLTQILSATME 467
+V++ K+ ++ W + + F K KF L IL+ E
Sbjct: 420 CIVTSGKSHVHFWNWSGGVGVPGNGTLTRKQGVFGKYKKPKFIPCFVFLPDGDILTGDSE 479
Query: 468 GKLVVWDIHRPPSSAST 484
G ++ W R PS + T
Sbjct: 480 GNILTWG--RSPSDSKT 494
Score = 35.0 bits (79), Expect = 0.41
Identities = 24/114 (21%), Positives = 54/114 (47%), Gaps = 10/114 (8%)
Query: 609 ICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFEKGLGVQSLTYNPEGALLGAGF 668
+CA HP ++A+G G V + E ++ + S V + + + Y+P+G L G
Sbjct: 642 LCA-DFHPSGAVVAVGLNTGRWLVLDTETRE-IVSDVIDGNEQLSVVRYSPDGLYLAIGS 699
Query: 669 TEGTVYILDAMSLENESPEPFKYSR-----TSVTHISFSHDSQYMATADRSFTV 717
+ +YI S+ ++ + ++ R + +TH+ +S D ++ + + +
Sbjct: 700 HDNVIYI---YSVSSDGAKSSRFGRCMGHSSFITHLDWSKDGNFIMSNSGDYEI 750
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 50.4 bits (119), Expect = 9e-06
Identities = 51/213 (23%), Positives = 93/213 (43%), Gaps = 31/213 (14%)
Query: 6 EAPREATG-ENGETEMKEE----EEPNPNYKEV---------EDPQQESKDDTIAWRESQ 51
E+ REA G E+ E E+K+E EE +E+ E + E K+ T+A + +
Sbjct: 97 ESQREAGGKEDAEAELKKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQK 156
Query: 52 EEERKTGEEEGE--EEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQE-VTASMI 108
EE++ E G+ + DK EE+ + +E +G ++E + EP+E T
Sbjct: 157 AEEKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEA 216
Query: 109 RLETQ--ITDSQSITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISP 166
+ E+Q + + ++ PK G + E+A+ E D + + SP
Sbjct: 217 KAESQKAVVEDEAKAE---PKEPDGKEEAKHGAKEEADAKEEAEDAE------EAEPGSP 267
Query: 167 EEQQISSPERQP---SGELEEKTDRMPQDELGQ 196
E+Q E++P +G + + P+ G+
Sbjct: 268 SEEQEQDVEKEPEGGAGVIPSSPEEWPESPTGE 300
Score = 39.7 bits (91), Expect = 0.017
Identities = 42/189 (22%), Positives = 80/189 (42%), Gaps = 13/189 (6%)
Query: 9 REATGENGE-TEMKEEEEPNPNYK-EVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEG 66
+EA E+G+ + + ++P P E ED + S+++T +E E ++ +E E +
Sbjct: 160 KEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDE-EAKA 218
Query: 67 KEDKKIVMEETE---------EKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDS 117
+ K +V +E + E+A ++EA +E E E + E +
Sbjct: 219 ESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDVEKE 278
Query: 118 QSITSGIFPKTQRGSKSKLSLQLEDAETDELLRD-LSTQIEFLDLDQISPEEQQISSPER 176
+G+ P + + + + TD L D +++ + SP + S PE
Sbjct: 279 PEGGAGVIPSSPEEWPESPTGEGHNLSTDGLGPDCVASGQTSPSASESSPSDVPQSPPES 338
Query: 177 QPSGELEEK 185
SGE +EK
Sbjct: 339 PSSGEKKEK 347
Score = 38.9 bits (89), Expect = 0.028
Identities = 42/213 (19%), Positives = 86/213 (40%), Gaps = 19/213 (8%)
Query: 10 EATGE-NGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKE 68
E GE NG E+K E + KE + + + +D GE+E G +
Sbjct: 83 ELQGEANGLDEVKVESQREAGGKEDAEAELKKED---------------GEKEETTVGSQ 127
Query: 69 DKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEV-TASMIRLETQITDSQSITSGIFPK 127
+ EET+ + E +EKE++ E+ E +E S + + D + + +
Sbjct: 128 EMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEPKATVEEE 187
Query: 128 TQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTD 187
+ + + + Q ++ T+ ++ +T E Q + E + + ++P G+ E K
Sbjct: 188 DAKTASQEETGQRKECSTEP--KEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHG 245
Query: 188 RMPQDELGQERRDLEPENREEGQERRVSDIQSK 220
+ + +E D E E + D++ +
Sbjct: 246 AKEEADAKEEAEDAEEAEPGSPSEEQEQDVEKE 278
Score = 30.8 bits (68), Expect = 7.7
Identities = 42/202 (20%), Positives = 76/202 (37%), Gaps = 46/202 (22%)
Query: 79 EKAGEVQEKEASGIQEETTVEPQEVTASMI-----RLETQITDSQSITSGIFPKTQRGSK 133
E ++++KE ++ TTV P M ET+ T ++I G P T+ G +
Sbjct: 14 EAREKMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEG--PPTESGKQ 71
Query: 134 SKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGEL----------- 182
K ED + EL Q E LD++ E Q+ + + EL
Sbjct: 72 EKAPA--EDGMSAEL------QGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKEETT 123
Query: 183 --------------------EEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAG 222
EEK + ++ E ++ +PE+ ++ + KA
Sbjct: 124 VGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEPKAT 183
Query: 223 ISRESLVSSTTEDILFQKDKST 244
+ E +++ E+ +K+ ST
Sbjct: 184 VEEEDAKTASQEETGQRKECST 205
>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
Length = 295
Score = 49.7 bits (117), Expect = 2e-05
Identities = 51/199 (25%), Positives = 92/199 (46%), Gaps = 14/199 (7%)
Query: 1 MSDAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEE 60
MSD E E E E EEEE +++E ED Q+E+ ++ A E++ EE + E+
Sbjct: 1 MSDIEEVVEEYEEEEQEEAAVEEEE---DWREDEDEQEEAAEED-AEAEAETEETRAEED 56
Query: 61 EGEEEGKEDKKIVMEETEEKAGE-VQEKEASGIQEETTVEPQEVTASMIRLETQITDSQS 119
E EEE KE + MEE++ K + I + V+ ++ R+E + + Q+
Sbjct: 57 EEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRK--RMEKDLNELQA 114
Query: 120 ITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPS 179
+ F ++ + +SL+ D + R + + E + +E+Q E +
Sbjct: 115 LIEAHFENRKKEEEELVSLK------DRIERRRAERAEQQRIRNEREKERQNRLAEERAR 168
Query: 180 GELEEKTDRMPQDELGQER 198
E EE+ R +DE +++
Sbjct: 169 RE-EEENRRKAEDEARKKK 186
Score = 48.9 bits (115), Expect = 3e-05
Identities = 46/205 (22%), Positives = 94/205 (45%), Gaps = 26/205 (12%)
Query: 20 MKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGK-EDKKIVMEETE 78
M + EE Y+E E+ ++ + ++ WRE ++E+ + EE+ E E + E+ + +E E
Sbjct: 1 MSDIEEVVEEYEE-EEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEE 59
Query: 79 EKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKSKLSL 138
E+A E ++ G EE+ +P+ +++ PK G +
Sbjct: 60 EEAKEAED----GPMEESKPKPRSFMPNLVP----------------PKIPDGERVDFD- 98
Query: 139 QLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSP---ERQPSGELEEKTDRMPQDELG 195
+ ++ L +L IE ++ EE+ +S ER+ + E++ R +++
Sbjct: 99 DIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKER 158
Query: 196 QERRDLEPENREEGQERRVSDIQSK 220
Q R E REE + RR ++ +++
Sbjct: 159 QNRLAEERARREEEENRRKAEDEAR 183
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 49.7 bits (117), Expect = 2e-05
Identities = 53/220 (24%), Positives = 94/220 (42%), Gaps = 14/220 (6%)
Query: 5 AEAP--REATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEG 62
A AP +E GE E E +EEEE + D +E + E +E E++ GE E
Sbjct: 515 ATAPEVKEEEGEKEEEEGQEEEEEEDEGAK-SDQAEEGGSEKEGSSEKEEGEQEEGETEA 573
Query: 63 EEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITS 122
E EG+E + ++ EEK+ EV KE + + +P++ + + + + +
Sbjct: 574 EAEGEEAEAKEEKKVEEKSEEVATKEEL-VADAKVEKPEKAKSPVPKSPVEEKGKSPV-- 630
Query: 123 GIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQI--SPEEQQISSPERQPSG 180
PK+ K K + E + +E + SP E++ SP P
Sbjct: 631 ---PKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSP--VPKS 685
Query: 181 ELEEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSK 220
+EE + + G+++ + E E +E +E +V + K
Sbjct: 686 PVEEAKSKAEVGK-GEQKEEEEKEVKEAPKEEKVEKKEEK 724
Score = 46.2 bits (108), Expect = 2e-04
Identities = 57/229 (24%), Positives = 91/229 (39%), Gaps = 27/229 (11%)
Query: 1 MSDAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWR--ESQEEERKTG 58
M +A A E + + E KE E E E+ + +K + E +EEE +
Sbjct: 469 MEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKE 528
Query: 59 EEEGEEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQ 118
EEEG+EE +E+ + + E+ G EKE S +EE E E A E + + +
Sbjct: 529 EEEGQEEEEEEDEGAKSDQAEEGGS--EKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEK 586
Query: 119 SITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQI--SPEEQQISSPER 176
+ KS+ E A +EL+ D + + SP E++ SP
Sbjct: 587 KVE----------EKSE-----EVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSP-- 629
Query: 177 QPSGELEEK----TDRMPQDELGQERRDLEPENREEGQERRVSDIQSKA 221
P +EEK + P +E G+ P + S ++ KA
Sbjct: 630 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA 678
Score = 40.8 bits (94), Expect = 0.007
Identities = 46/194 (23%), Positives = 82/194 (42%), Gaps = 17/194 (8%)
Query: 8 PREATGENGETEMK----EEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGE 63
P+ E G++ + EE+ +P K P +E+K + Q+EE E+E +
Sbjct: 657 PKSPVEEKGKSPVSKSPVEEKAKSPVPKS---PVEEAKSKAEVGKGEQKEEE---EKEVK 710
Query: 64 EEGKEDKKIVMEETEEKAGEVQEKEA--SGIQEETTVEPQEVTASM-IRLETQITDSQSI 120
E KE+K +E+ EEK +V EK+ S ++EE E +T S+ + LE + +
Sbjct: 711 EAPKEEK---VEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKP 767
Query: 121 TSGIFPKTQRGSKSKLSLQLED-AETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPS 179
K + G + + D D++ E +++ E ++ S +
Sbjct: 768 LQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEK 827
Query: 180 GELEEKTDRMPQDE 193
G + D P DE
Sbjct: 828 GVVTNGLDLSPADE 841
Score = 39.7 bits (91), Expect = 0.017
Identities = 40/182 (21%), Positives = 77/182 (42%), Gaps = 37/182 (20%)
Query: 49 ESQEEERKTGEEEGEEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMI 108
E++ E+ K+ EE E+ + M+E +++A E +E+E +EE + V A+
Sbjct: 459 ETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAP 518
Query: 109 RLETQITDSQSITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEE 168
+ K + G K + Q E+ E DE + ++
Sbjct: 519 EV----------------KEEEGEKEEEEGQEEEEEEDEGAKS---------------DQ 547
Query: 169 QQISSPERQPSGELEEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESL 228
+ E++ S E EE + E G+ + E E E +E++V + +S+ ++E L
Sbjct: 548 AEEGGSEKEGSSEKEE-----GEQEEGETEAEAEGEEAEAKEEKKVEE-KSEEVATKEEL 601
Query: 229 VS 230
V+
Sbjct: 602 VA 603
Score = 36.6 bits (83), Expect = 0.14
Identities = 44/195 (22%), Positives = 86/195 (44%), Gaps = 21/195 (10%)
Query: 32 EVEDPQQESKDDTIAWRE----SQEEERKTGEEEGEEEGK-EDKKIVMEETEEKAG--EV 84
+VED + E ++ A E S +EE+K EE EEE + E++++ +++ KA EV
Sbjct: 461 KVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEV 520
Query: 85 QEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKSKLSLQLEDAE 144
+E+E +EE E +E E + S G + GS K + E+ E
Sbjct: 521 KEEEGEKEEEEGQEEEEE--------EDEGAKSDQAEEG--GSEKEGSSEKEEGEQEEGE 570
Query: 145 TDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTD--RMPQDELGQERRDLE 202
T+ + E + ++ + +++++ E + EK + + P + E +
Sbjct: 571 TEAEAE--GEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKS 628
Query: 203 PENREEGQERRVSDI 217
P + +E+ S +
Sbjct: 629 PVPKSPVEEKGKSPV 643
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 49.7 bits (117), Expect = 2e-05
Identities = 53/220 (24%), Positives = 94/220 (42%), Gaps = 14/220 (6%)
Query: 5 AEAP--REATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEG 62
A AP +E GE E E +EEEE + D +E + E +E E++ GE E
Sbjct: 139 ATAPEVKEEEGEKEEEEGQEEEEEEDEGAK-SDQAEEGGSEKEGSSEKEEGEQEEGETEA 197
Query: 63 EEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITS 122
E EG+E + ++ EEK+ EV KE + + +P++ + + + + +
Sbjct: 198 EAEGEEAEAKEEKKVEEKSEEVATKEEL-VADAKVEKPEKAKSPVPKSPVEEKGKSPV-- 254
Query: 123 GIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQI--SPEEQQISSPERQPSG 180
PK+ K K + E + +E + SP E++ SP P
Sbjct: 255 ---PKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSP--VPKS 309
Query: 181 ELEEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSK 220
+EE + + G+++ + E E +E +E +V + K
Sbjct: 310 PVEEAKSKAEVGK-GEQKEEEEKEVKEAPKEEKVEKKEEK 348
Score = 46.2 bits (108), Expect = 2e-04
Identities = 57/229 (24%), Positives = 91/229 (39%), Gaps = 27/229 (11%)
Query: 1 MSDAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWR--ESQEEERKTG 58
M +A A E + + E KE E E E+ + +K + E +EEE +
Sbjct: 93 MEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKE 152
Query: 59 EEEGEEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQ 118
EEEG+EE +E+ + + E+ G EKE S +EE E E A E + + +
Sbjct: 153 EEEGQEEEEEEDEGAKSDQAEEGGS--EKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEK 210
Query: 119 SITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQI--SPEEQQISSPER 176
+ KS+ E A +EL+ D + + SP E++ SP
Sbjct: 211 KVE----------EKSE-----EVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSP-- 253
Query: 177 QPSGELEEK----TDRMPQDELGQERRDLEPENREEGQERRVSDIQSKA 221
P +EEK + P +E G+ P + S ++ KA
Sbjct: 254 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA 302
Score = 40.8 bits (94), Expect = 0.007
Identities = 46/194 (23%), Positives = 82/194 (42%), Gaps = 17/194 (8%)
Query: 8 PREATGENGETEMK----EEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGE 63
P+ E G++ + EE+ +P K P +E+K + Q+EE E+E +
Sbjct: 281 PKSPVEEKGKSPVSKSPVEEKAKSPVPKS---PVEEAKSKAEVGKGEQKEEE---EKEVK 334
Query: 64 EEGKEDKKIVMEETEEKAGEVQEKEA--SGIQEETTVEPQEVTASM-IRLETQITDSQSI 120
E KE+K +E+ EEK +V EK+ S ++EE E +T S+ + LE + +
Sbjct: 335 EAPKEEK---VEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKP 391
Query: 121 TSGIFPKTQRGSKSKLSLQLED-AETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPS 179
K + G + + D D++ E +++ E ++ S +
Sbjct: 392 LQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEK 451
Query: 180 GELEEKTDRMPQDE 193
G + D P DE
Sbjct: 452 GVVTNGLDLSPADE 465
Score = 39.7 bits (91), Expect = 0.017
Identities = 40/182 (21%), Positives = 77/182 (42%), Gaps = 37/182 (20%)
Query: 49 ESQEEERKTGEEEGEEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMI 108
E++ E+ K+ EE E+ + M+E +++A E +E+E +EE + V A+
Sbjct: 83 ETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAP 142
Query: 109 RLETQITDSQSITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEE 168
+ K + G K + Q E+ E DE + ++
Sbjct: 143 EV----------------KEEEGEKEEEEGQEEEEEEDEGAKS---------------DQ 171
Query: 169 QQISSPERQPSGELEEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESL 228
+ E++ S E EE + E G+ + E E E +E++V + +S+ ++E L
Sbjct: 172 AEEGGSEKEGSSEKEE-----GEQEEGETEAEAEGEEAEAKEEKKVEE-KSEEVATKEEL 225
Query: 229 VS 230
V+
Sbjct: 226 VA 227
Score = 36.6 bits (83), Expect = 0.14
Identities = 44/195 (22%), Positives = 86/195 (44%), Gaps = 21/195 (10%)
Query: 32 EVEDPQQESKDDTIAWRE----SQEEERKTGEEEGEEEGK-EDKKIVMEETEEKAG--EV 84
+VED + E ++ A E S +EE+K EE EEE + E++++ +++ KA EV
Sbjct: 85 KVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEV 144
Query: 85 QEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKSKLSLQLEDAE 144
+E+E +EE E +E E + S G + GS K + E+ E
Sbjct: 145 KEEEGEKEEEEGQEEEEE--------EDEGAKSDQAEEG--GSEKEGSSEKEEGEQEEGE 194
Query: 145 TDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTD--RMPQDELGQERRDLE 202
T+ + E + ++ + +++++ E + EK + + P + E +
Sbjct: 195 TEAEAE--GEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKS 252
Query: 203 PENREEGQERRVSDI 217
P + +E+ S +
Sbjct: 253 PVPKSPVEEKGKSPV 267
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 49.7 bits (117), Expect = 2e-05
Identities = 54/231 (23%), Positives = 89/231 (38%), Gaps = 28/231 (12%)
Query: 8 PREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGK 67
P G E +EE P K VE+ E + + +Q E + EEE +GK
Sbjct: 114 PPAKNGVAAEVSPAKEENPRRASKAVEESSDEERQRDLP---AQRGEESSEEEEKGYKGK 170
Query: 68 EDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPK 127
KK V+++ V K+A EE+ EP + TA K
Sbjct: 171 TRKKPVVKKQAPGKASVSRKQAREESEESEAEPVQRTA---------------------K 209
Query: 128 TQRGSKSKLSLQLEDAETDELL---RDLSTQIEFLDLDQISPEEQQISSPERQPSGELEE 184
G+K SL+ + E++E + + + E + ++ EE+ P + +G +
Sbjct: 210 KVEGNKGTKSLKESEQESEEEILAQKKEQREEEVEEEEKEEDEEKGDWKPRTRSNGRRKS 269
Query: 185 KTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESLVSSTTED 235
+ + Q +R L + EE Q+ S +G RE V +ED
Sbjct: 270 AREERSCKQKSQAKRLLGDSDSEEEQKEAASS-GDDSGRDREPPVQRKSED 319
Score = 42.0 bits (97), Expect = 0.003
Identities = 50/238 (21%), Positives = 100/238 (42%), Gaps = 25/238 (10%)
Query: 4 AAEAPREATGENGETEMK------EEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKT 57
A+ + ++A E+ E+E + ++ E N K +++ +QES+++ +A ++ Q EE
Sbjct: 185 ASVSRKQAREESEESEAEPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKKEQREEEVE 244
Query: 58 GEEEGEEEGKEDKKI------VMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLE 111
EE+ E+E K D K + E+ Q+ +A + ++ E ++ A+ +
Sbjct: 245 EEEKEEDEEKGDWKPRTRSNGRRKSAREERSCKQKSQAKRLLGDSDSEEEQKEAASSGDD 304
Query: 112 TQITDSQSITSGIFPKTQRGSKSKLSLQLEDAE-----------TDELLRDLSTQIEFLD 160
+ + +TQ +LS ED E + ++ R ST E D
Sbjct: 305 SGRDREPPVQRKSEDRTQLKGGKRLSGSSEDEEDSGKGEPTAKGSRKMARLGSTSGEESD 364
Query: 161 LDQISPEEQQISSPERQPSGELEEKTDRMPQDELGQERRDLEPENR--EEGQERRVSD 216
L++ + + P+ + +K+ R + D PE + + G RR D
Sbjct: 365 LEREVSDSEAGGGPQGERKNRSSKKSSRKGRTRSSSSSSDGSPEAKGGKAGSGRRGED 422
>gi|22749037 WD repeat domain 65 [Homo sapiens]
Length = 698
Score = 49.7 bits (117), Expect = 2e-05
Identities = 114/558 (20%), Positives = 217/558 (38%), Gaps = 84/558 (15%)
Query: 263 VYYIREERQRVLLYVCAHTAIIYNVFRNNQYHLQGHANI--ISCLCVSEDRRWIATADKG 320
++Y E+ ++++ + + YNV + Q + G + L +S +RR++A ++
Sbjct: 22 IFYFDEQ---IIIFPSGNHCVKYNVDQKWQKFIPGSEKSQGMLALSISPNRRYLAISETV 78
Query: 321 PDCLVIIWDSFTGIP-----VHTIFDSCPEGNGIMAMAMTHDAKYLATISDAEVQKVCIW 375
+ I + IP V FD + ++MA + D+KYL + + W
Sbjct: 79 QEKPAITIYELSSIPCRKRKVLNNFDF--QVQKFISMAFSPDSKYLLAQTSPPESNLVYW 136
Query: 376 KWTLAVETPACTLELPTEYGVQNYVTFNPTNNKE--LVSNSKTRAIYYAWYEERDTLAHS 433
W + + + T+ V+F+P +N + + N + + +A
Sbjct: 137 LWEK--QKVMAIVRIDTQNNPVYQVSFSPQDNTQVCVTGNGMFKLLRFA----------- 183
Query: 434 APLLTEKTFNKLVGKFSQSIFHLNLT--QILSATMEGKLVVWDIHRPPSSASTFLGFPYI 491
L + +F + G+ + H + +I+ T GKL +++ S + P
Sbjct: 184 EGTLKQTSFQR--GEPQNYLAHTWVADDKIVVGTDTGKLFLFESGDQRWETSIMVKEPTN 241
Query: 492 KPCKLVHLQK-----EGITVLTTIDSYIVTGDIKGNIKFYDHTLSIVNWYSH---LKLGA 543
L +Q+ E V + + SY + + + + YS G
Sbjct: 242 GSKSLDVIQESESLIEFPPVSSPLPSYEQMVAASSHSQMSMPQVFAIAAYSKGFACSAGP 301
Query: 544 IRTLSFSKTPATP----------PTEKSNYPPDCTLKGDLFVL------RNFIIGTSDAA 587
R L F K P + + P + K D+ L + TS
Sbjct: 302 GRVLLFEKMEEKDFYRESREIRIPVDPQSNDPSQSDKQDVLCLCFSPSEETLVASTSKNQ 361
Query: 588 VYHLTTDGTKLEK---------LFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYE-N 637
+Y +T T++ K ++ I ++ +PLIA S+ I++WNYE N
Sbjct: 362 LYSITMSLTEISKGEPAHFEYLMYPLHSAPITGLATCIRKPLIATCSLDRSIRLWNYETN 421
Query: 638 KQYLFSRVFEKGLGVQSLTYNPEGALLGAGFTEGTVYILDAMSLENESPEPFK-YSRTSV 696
LF E+ S++ +P G + GF + L M+L + FK YS
Sbjct: 422 TLELFKEYQEE---AYSISLHPSGHFIVVGFADK----LRLMNLLIDDIRSFKEYSVRGC 474
Query: 697 THISFSHDSQYMATADRSFTVAVYMLVVRNGQRVWEYLARLRSHRKSIRSLLFGVYLDSN 756
SFS+ A + + + VY E ++ L+ H IRS+++ +++
Sbjct: 475 GECSFSNGGHLFAAVNGN-VIHVYTTT------SLENISSLKGHTGKIRSIVW----NAD 523
Query: 757 EPRLLSLGTDRLLIEYDL 774
+ +L+S GTD + E++L
Sbjct: 524 DSKLISGGTDGAVYEWNL 541
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 48.9 bits (115), Expect = 3e-05
Identities = 55/236 (23%), Positives = 114/236 (48%), Gaps = 24/236 (10%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEE---EGEEEGKEDKKIV 73
E E++E+E+ +E Q+E + QEE+ + E+ E E+E +E +K +
Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL 299
Query: 74 MEETE--EKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRG 131
E+ + E+ ++QE+E ++E + QE M R E ++ + + K R
Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQE--EKMWRQEERLWEQE--------KQMRE 349
Query: 132 SKSKLSLQLEDA-ETDELLRD----LSTQIEFLDLDQISPEEQQISSPERQPSGELEEKT 186
+ K+ Q E E DE LR+ + Q + + ++ EE++I ER+ EE+T
Sbjct: 350 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIR--EREKKMREEEET 407
Query: 187 DRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESLVSSTTEDILFQKDK 242
R ++++ ++ ++ + +E Q++R+ + + K + + + E I Q++K
Sbjct: 408 MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK--LWEQEKMQEQEEKIWEQEEK 461
Score = 47.0 bits (110), Expect = 1e-04
Identities = 47/207 (22%), Positives = 93/207 (44%), Gaps = 19/207 (9%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKDDTIAWR--ESQEEERKTGEEEGEEEGKEDKKIVM 74
E M E++E +E E+ +E K W+ E EE+KT E+E + +E+K
Sbjct: 506 EERMWEQDE---RLREKEERMREQKK---MWQQEEKMREEKKTQEQEKKTWDQEEKMREE 559
Query: 75 EETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKS 134
E E+ +++E+E ++E ++ QE M E ++ + + + + +
Sbjct: 560 ERMREREKKMREEEEMMREQEEKMQEQE--EKMREQEEKMWEQE--------EKMQEQEE 609
Query: 135 KLSLQLEDAETDELLRDLSTQIEFL-DLDQISPEEQQISSPERQPSGELEEKTDRMPQDE 193
K+ Q E E + Q E + + ++ E+++ + + E EEK +
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 669
Query: 194 LGQERRDLEPENREEGQERRVSDIQSK 220
GQE + E E + +GQE ++ + + K
Sbjct: 670 QGQEEKMREQEEKMQGQEEKMREQEEK 696
Score = 46.6 bits (109), Expect = 1e-04
Identities = 52/203 (25%), Positives = 93/203 (45%), Gaps = 12/203 (5%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGK-EDKKIVME 75
E +M+EEE K++ + ++ ++ +E +E+ R+ E+ E+E K ++++ M
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW 612
Query: 76 ETEEKAGEVQEKEASGIQEETTVEP----QEVTASMIRLETQITDSQSITSGIFPKTQRG 131
E EEK E +E++ QEE E QE M E ++ + + K Q G
Sbjct: 613 EQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ-G 671
Query: 132 SKSKLSLQLEDAE-TDELLRDLSTQIEFLDLDQISPEEQQISSPERQ-PSGELEEKTDRM 189
+ K+ Q E + +E +R+ ++ + EE+ E+ E+ EK +R+
Sbjct: 672 QEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERI 731
Query: 190 -PQDELGQERRDLEPENREEGQE 211
Q E QER PE+ E E
Sbjct: 732 RDQKEKMQERL---PEHEERCSE 751
Score = 46.2 bits (108), Expect = 2e-04
Identities = 55/232 (23%), Positives = 104/232 (44%), Gaps = 33/232 (14%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIVMEE 76
E +M+EE++ K+ D +++ +++ +E E+K EEE +E+K M+E
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREE----ERMREREKKMREEEEMMREQEEK---MQE 585
Query: 77 TEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKSKL 136
EEK E +EK QEE E +E M E ++ + + + K+
Sbjct: 586 QEEKMREQEEKMWE--QEEKMQEQEE---KMWEQEEKMWEQE-------------EEDKM 627
Query: 137 SLQLEDA-ETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDRMPQDELG 195
Q E E +E +++ ++ + +++ +E+++ E + G+ EEK + G
Sbjct: 628 QEQEEMMWEQEEKMQEQEEKM-WEQEEKMREQEEKMREQEEKMQGQ-EEKMREQEEKMQG 685
Query: 196 QERRDLEPENREEGQERRVSDIQSKAGISRESL-----VSSTTEDILFQKDK 242
QE + E E + GQE ++ + K E + + E I QK+K
Sbjct: 686 QEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEK 737
Score = 45.8 bits (107), Expect = 2e-04
Identities = 45/205 (21%), Positives = 92/205 (44%), Gaps = 28/205 (13%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIVMEE 76
+ +M E+EE + + + +++ +++ RE +E+ +K E E+E KE ++ + E
Sbjct: 378 QEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 437
Query: 77 TEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKSKL 136
+EK + E+E QEE E +E +I D + + G + K+
Sbjct: 438 QKEK---LWEQEKMQEQEEKIWEQEE----------KIRDQEEMW---------GQEKKM 475
Query: 137 SLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDRM-PQDELG 195
Q + E ++ + + ++ + EE+ ER L EK +RM Q ++
Sbjct: 476 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER-----LREKEERMREQKKMW 530
Query: 196 QERRDLEPENREEGQERRVSDIQSK 220
Q+ + E + + QE++ D + K
Sbjct: 531 QQEEKMREEKKTQEQEKKTWDQEEK 555
Score = 43.1 bits (100), Expect = 0.002
Identities = 49/229 (21%), Positives = 97/229 (42%), Gaps = 30/229 (13%)
Query: 9 REATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEE-----ERKTGEEEGE 63
RE E M+E+EE +E Q+E + + QEE E K E+E E
Sbjct: 565 REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE 624
Query: 64 EEGKEDKKIV------MEETEEKAGEVQEK-------------EASGIQEETTVEPQEVT 104
++ +E ++++ M+E EEK E +EK + G +E+ + +++
Sbjct: 625 DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684
Query: 105 ASMIRLETQITDSQSITSGIFPKTQR--GSKSKLSLQLEDAETDELLRDLSTQIEFLDLD 162
++ Q + ++ + ++ G + K+ Q E E +E +RD +++ +
Sbjct: 685 GQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQ----E 740
Query: 163 QISPEEQQISSPERQPSGELEEKTDRMPQDELGQERRDLEPENREEGQE 211
++ E++ S P PS L + + G E + P++ QE
Sbjct: 741 RLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGGEAGEGSPQDNPTAQE 789
Score = 39.7 bits (91), Expect = 0.017
Identities = 48/209 (22%), Positives = 89/209 (42%), Gaps = 16/209 (7%)
Query: 17 ETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIVMEE 76
E +M E+EE ++ D +Q+ D E E R E EE +E KK+ +E
Sbjct: 485 EDQMWEQEE------KMRDQEQKMWDQEERMWEQDERLR-----EKEERMREQKKMWQQE 533
Query: 77 T---EEKAGEVQEKEASGIQEETTVEPQ-EVTASMIRLETQITDSQSITSGIFPKTQRGS 132
EEK + QEK+ +E+ E + +R E ++ Q + R
Sbjct: 534 EKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ 593
Query: 133 KSKLSLQLED-AETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDRMPQ 191
+ K+ Q E E +E + + ++ + + E++++ + + E EEK +
Sbjct: 594 EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEE 653
Query: 192 DELGQERRDLEPENREEGQERRVSDIQSK 220
QE + E E + +GQE ++ + + K
Sbjct: 654 KMREQEEKMREQEEKMQGQEEKMREQEEK 682
Score = 32.7 bits (73), Expect = 2.0
Identities = 44/229 (19%), Positives = 95/229 (41%), Gaps = 21/229 (9%)
Query: 1 MSDAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEE 60
+ + E +E + E E K E+ +++ E ++ K ++ +++E + E+
Sbjct: 305 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364
Query: 61 EGEEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSI 120
+ KE++ E+ E+ ++QE+E +E+ E +E + Q Q
Sbjct: 365 DERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEET------MREQEEKMQKQ 418
Query: 121 TSGIFPKTQR--------GSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQIS 172
++ + ++ K KL Q + E +E + + +I D +++ +E+++
Sbjct: 419 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR--DQEEMWGQEKKMW 476
Query: 173 SPER-----QPSGELEEKTDRMPQDELGQERRDLEPENREEGQERRVSD 216
E+ E EEK Q QE R E + R +E R+ +
Sbjct: 477 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMRE 525
Score = 30.8 bits (68), Expect = 7.7
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 6/111 (5%)
Query: 1 MSDAAEAPREATGE-NGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGE 59
M + E RE + G+ E E+E +E + +QE K + +EE+ G+
Sbjct: 655 MREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQ 714
Query: 60 EE---GEEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASM 107
EE G+EE +E ++ + ++ E+ + E E E + P +V +M
Sbjct: 715 EEKMWGQEEMREKEERIRDQKEKMQERLPEHEER--CSEPCLPPSKVLCNM 763
>gi|6912356 echinoderm microtubule associated protein like 2 [Homo
sapiens]
Length = 649
Score = 48.9 bits (115), Expect = 3e-05
Identities = 51/215 (23%), Positives = 85/215 (39%), Gaps = 31/215 (14%)
Query: 274 LLYVCAHTAIIYNVFRNNQYHLQGHANIISCLCVSEDRRWIATAD--------KGPDCLV 325
++Y A A++Y+V Q H GH + I CL + D IAT K V
Sbjct: 80 IVYFVASVAVLYSVEEQRQRHYLGHNDDIKCLAIHPDMVTIATGQVAGTTKEGKPLPPHV 139
Query: 326 IIWDSFTGIPVHTIFDSCPEGNGIMAMAM-------THDAKYLATISDAEVQKVCIWKWT 378
IWDS + +H + G G+ A+ ++ L + ++ + +W W
Sbjct: 140 RIWDSVSLSTLHVL------GLGVFDRAVCCVGFSKSNGGNLLCAVDESNDHMLSVWDW- 192
Query: 379 LAVETPACTLELPTEYGVQNYVTFNPTNNKELVSNSKTRAIYYAWYEERDTLAHSAPLLT 438
A ET ++ E + TF+PT+ L++ K+ Y W E +L+ L
Sbjct: 193 -AKETKVVDVKCSNEAVL--VATFHPTDPTVLITCGKSH--IYFWTLEGGSLSKRQGLFE 247
Query: 439 EKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVW 473
+ K V + L +++ G L VW
Sbjct: 248 KHEKPKYV----LCVTFLEGGDVVTGDSGGNLYVW 278
Score = 40.8 bits (94), Expect = 0.007
Identities = 34/141 (24%), Positives = 61/141 (43%), Gaps = 6/141 (4%)
Query: 607 DAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFEKGLGVQSLTYNPEGALLGA 666
+ + ++ HP + ++ +W+ ++ Q L+SR+ E +S ++P G++L
Sbjct: 378 EELWGLATHPSRAQFVTCGQDKLVHLWSSDSHQPLWSRIIEDP--ARSAGFHPSGSVLAV 435
Query: 667 GFTEGTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADRSFTVAVYMLVVRN 726
G G +LD + + + + SV +SFS D Y+A S VY+ V
Sbjct: 436 GTVTGRWLLLDTETHDLVAIHTDGNEQISV--VSFSPDGAYLAVG--SHDNLVYVYTVDQ 491
Query: 727 GQRVWEYLARLRSHRKSIRSL 747
G R L + H I L
Sbjct: 492 GGRKVSRLGKCSGHSSFITHL 512
Score = 32.3 bits (72), Expect = 2.7
Identities = 13/32 (40%), Positives = 19/32 (59%)
Query: 890 HPNGVAGMAVSYDGCYAFTAGGHDRSVVQWKI 921
H + V +A +D A T GG D SV+QW++
Sbjct: 617 HSSHVTNVAFLWDDSMALTTGGKDTSVLQWRV 648
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,691,477
Number of Sequences: 37866
Number of extensions: 2201250
Number of successful extensions: 22851
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 281
Number of HSP's successfully gapped in prelim test: 777
Number of HSP's that attempted gapping in prelim test: 11189
Number of HSP's gapped (non-prelim): 5850
length of query: 1149
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1036
effective length of database: 13,968,660
effective search space: 14471531760
effective search space used: 14471531760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.