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Search of human proteins with 109637771
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109637771 calpastatin isoform l [Homo sapiens]
(654 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109637771 calpastatin isoform l [Homo sapiens] 1295 0.0
gi|109637767 calpastatin isoform j [Homo sapiens] 1286 0.0
gi|109637759 calpastatin isoform f [Homo sapiens] 1286 0.0
gi|109637769 calpastatin isoform k [Homo sapiens] 1284 0.0
gi|109637757 calpastatin isoform e [Homo sapiens] 1284 0.0
gi|109637763 calpastatin isoform h [Homo sapiens] 1274 0.0
gi|27765085 calpastatin isoform b [Homo sapiens] 1274 0.0
gi|109637761 calpastatin isoform g [Homo sapiens] 1273 0.0
gi|109637765 calpastatin isoform i [Homo sapiens] 1262 0.0
gi|109637753 calpastatin isoform a [Homo sapiens] 1262 0.0
gi|27765087 calpastatin isoform c [Homo sapiens] 781 0.0
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 91 3e-18
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 67 5e-11
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 67 5e-11
gi|150170670 piccolo isoform 2 [Homo sapiens] 67 7e-11
gi|150378539 piccolo isoform 1 [Homo sapiens] 67 7e-11
gi|104526627 triadin [Homo sapiens] 66 1e-10
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 62 1e-09
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 62 1e-09
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 62 1e-09
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 62 1e-09
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 62 1e-09
gi|109637791 transcription factor-like nuclear regulator [Homo s... 62 1e-09
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 60 5e-09
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 58 3e-08
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 57 7e-08
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 55 2e-07
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 55 3e-07
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 55 3e-07
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 55 3e-07
>gi|109637771 calpastatin isoform l [Homo sapiens]
Length = 654
Score = 1295 bits (3352), Expect = 0.0
Identities = 654/654 (100%), Positives = 654/654 (100%)
Query: 1 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT
Sbjct: 1 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
Query: 61 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI 120
KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI
Sbjct: 61 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI 120
Query: 121 DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDDAIDA 180
DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDDAIDA
Sbjct: 121 DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDDAIDA 180
Query: 181 LSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEAL 240
LSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEAL
Sbjct: 181 LSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEAL 240
Query: 241 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 300
SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP
Sbjct: 241 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 300
Query: 301 EPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCS 360
EPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCS
Sbjct: 301 EPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCS 360
Query: 361 IQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKE 420
IQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKE
Sbjct: 361 IQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKE 420
Query: 421 ETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAK 480
ETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAK
Sbjct: 421 ETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAK 480
Query: 481 LAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDK 540
LAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDK
Sbjct: 481 LAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDK 540
Query: 541 VKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDAL 600
VKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDAL
Sbjct: 541 VKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDAL 600
Query: 601 SGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 654
SGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 601 SGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 654
>gi|109637767 calpastatin isoform j [Homo sapiens]
Length = 667
Score = 1286 bits (3328), Expect = 0.0
Identities = 654/667 (98%), Positives = 654/667 (98%), Gaps = 13/667 (1%)
Query: 1 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT
Sbjct: 1 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
Query: 61 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI 120
KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI
Sbjct: 61 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI 120
Query: 121 DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK---------- 170
DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK
Sbjct: 121 DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPAD 180
Query: 171 ---PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV 227
PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV
Sbjct: 181 SSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV 240
Query: 228 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 287
EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL
Sbjct: 241 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 300
Query: 288 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA 347
KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA
Sbjct: 301 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA 360
Query: 348 PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK 407
PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK
Sbjct: 361 PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK 420
Query: 408 AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG 467
AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG
Sbjct: 421 AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG 480
Query: 468 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR 527
PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR
Sbjct: 481 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR 540
Query: 528 QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS 587
QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS
Sbjct: 541 QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS 600
Query: 588 KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 647
KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE
Sbjct: 601 KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 660
Query: 648 TSKPKDD 654
TSKPKDD
Sbjct: 661 TSKPKDD 667
>gi|109637759 calpastatin isoform f [Homo sapiens]
Length = 750
Score = 1286 bits (3328), Expect = 0.0
Identities = 654/667 (98%), Positives = 654/667 (98%), Gaps = 13/667 (1%)
Query: 1 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT
Sbjct: 84 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 143
Query: 61 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI 120
KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI
Sbjct: 144 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI 203
Query: 121 DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK---------- 170
DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK
Sbjct: 204 DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPAD 263
Query: 171 ---PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV 227
PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV
Sbjct: 264 SSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV 323
Query: 228 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 287
EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL
Sbjct: 324 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 383
Query: 288 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA 347
KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA
Sbjct: 384 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA 443
Query: 348 PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK 407
PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK
Sbjct: 444 PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK 503
Query: 408 AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG 467
AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG
Sbjct: 504 AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG 563
Query: 468 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR 527
PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR
Sbjct: 564 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR 623
Query: 528 QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS 587
QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS
Sbjct: 624 QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS 683
Query: 588 KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 647
KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE
Sbjct: 684 KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 743
Query: 648 TSKPKDD 654
TSKPKDD
Sbjct: 744 TSKPKDD 750
Score = 223 bits (568), Expect = 4e-58
Identities = 188/630 (29%), Positives = 304/630 (48%), Gaps = 49/630 (7%)
Query: 40 KKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPV 99
+ A +R + SEK++E +KP + + + A + G + A V
Sbjct: 16 RAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASL----GSSQSSRTYAGGTASATKV 71
Query: 100 ESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSS--TYIEELGKRE 157
+ S S M+ + T PE+ + + P+ + S + ++ R
Sbjct: 72 SASSGATSKSSSMNPTETKAVKT--EPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRS 129
Query: 158 VTIPPKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSA 217
P + K P D I A + G +GK +K++ + ++ A
Sbjct: 130 AEQQPSEKSTEPK-TKPQDMISA-GGESVAGITAISGKPGDKKKEKK--------SLTPA 179
Query: 218 APPQEKKRKVEKDTMSDQALEALSASL-GTRQAEPELDLRSIKEVDEAKAKEEKLEKCGE 276
P + K K + D AL+ L +L G + E E + EV + + +E+ G+
Sbjct: 180 VPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMS-STYIEELGK 238
Query: 277 DDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTE 336
+ TIP +YR + K+G + P + KP + ID LS DF P+ +
Sbjct: 239 REVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDALSSDFTCG----SPTAAGK 291
Query: 337 KTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDAVEALADSLGKKEA 392
KTE+ ++ +E + S +++SA P + K T+ D A+EAL+ SLG ++A
Sbjct: 292 KTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQA 345
Query: 393 DPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPP 451
+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E +E+ P
Sbjct: 346 EPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-EPEEKPKP 404
Query: 452 MSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTTQAGAPPR 504
SE L+D LSEDF + + + K E++K A A +SE V +T + Q+ APP
Sbjct: 405 RSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQS-APPE 463
Query: 505 DTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEY 564
+ DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++TIPP+Y
Sbjct: 464 PATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDY 523
Query: 565 RHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKK 624
R + KP+ P K+S++ P + +DALS D + + AK
Sbjct: 524 RLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAI 581
Query: 625 AASSSKAPKNGGKAKDSAKTTEETSKPKDD 654
+ S+ P + +A + T ++ K DD
Sbjct: 582 SEVVSQTPASTTQAGAPPRDTSQSDKDLDD 611
Score = 79.7 bits (195), Expect = 8e-15
Identities = 88/362 (24%), Positives = 152/362 (41%), Gaps = 42/362 (11%)
Query: 299 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEK--TEESKAAAPAPVSEAVC 354
+ +P +KP PR + + + E PSKP EK ++E KAA
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAA---------- 50
Query: 355 RTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEA-DPEDGKPVMDKVKEKAKEEDR 413
S+ S+ GT V A + + K + +P + K V + ++K++
Sbjct: 51 -----SLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQ---- 101
Query: 414 EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASS 473
K +++P D K + + +++Q S + +G ++ +
Sbjct: 102 ---STKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAG 158
Query: 474 LKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDE 533
+ K E S TPA ++ P + + +S +D ALD L D+LG + +E
Sbjct: 159 ITAISGKPGDKKKEKKSLTPAVPVES-KPDKPSGKS--GMDAALDDLIDTLGGPEETEEE 215
Query: 534 NKPME-DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPAD 592
N +V + + + ++LG+R+ TIPP+YR LL ++ PP DS KP
Sbjct: 216 NTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITGPPA----DSSKPIG 269
Query: 593 DQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPK 652
D IDALS D +C S T + T K++ + + A G + +A E+ K +
Sbjct: 270 PDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRKVE 324
Query: 653 DD 654
D
Sbjct: 325 KD 326
>gi|109637769 calpastatin isoform k [Homo sapiens]
Length = 673
Score = 1284 bits (3322), Expect = 0.0
Identities = 654/673 (97%), Positives = 654/673 (97%), Gaps = 19/673 (2%)
Query: 1 MNPTETKAVKTEPEKKSQSTK-------------------PKSLPKQASDTGSNDAHNKK 41
MNPTETKAVKTEPEKKSQSTK PKSLPKQASDTGSNDAHNKK
Sbjct: 1 MNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKK 60
Query: 42 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 101
AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES
Sbjct: 61 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 120
Query: 102 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 161
KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP
Sbjct: 121 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 180
Query: 162 PKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQ 221
PKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQ
Sbjct: 181 PKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQ 240
Query: 222 EKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETI 281
EKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETI
Sbjct: 241 EKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETI 300
Query: 282 PSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES 341
PSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES
Sbjct: 301 PSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES 360
Query: 342 KAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVM 401
KAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVM
Sbjct: 361 KAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVM 420
Query: 402 DKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDAL 461
DKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDAL
Sbjct: 421 DKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDAL 480
Query: 462 SEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLS 521
SEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLS
Sbjct: 481 SEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLS 540
Query: 522 DSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPT 581
DSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPT
Sbjct: 541 DSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPT 600
Query: 582 KKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDS 641
KKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDS
Sbjct: 601 KKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDS 660
Query: 642 AKTTEETSKPKDD 654
AKTTEETSKPKDD
Sbjct: 661 AKTTEETSKPKDD 673
>gi|109637757 calpastatin isoform e [Homo sapiens]
Length = 756
Score = 1284 bits (3322), Expect = 0.0
Identities = 654/673 (97%), Positives = 654/673 (97%), Gaps = 19/673 (2%)
Query: 1 MNPTETKAVKTEPEKKSQSTK-------------------PKSLPKQASDTGSNDAHNKK 41
MNPTETKAVKTEPEKKSQSTK PKSLPKQASDTGSNDAHNKK
Sbjct: 84 MNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKK 143
Query: 42 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 101
AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES
Sbjct: 144 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 203
Query: 102 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 161
KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP
Sbjct: 204 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 263
Query: 162 PKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQ 221
PKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQ
Sbjct: 264 PKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQ 323
Query: 222 EKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETI 281
EKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETI
Sbjct: 324 EKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETI 383
Query: 282 PSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES 341
PSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES
Sbjct: 384 PSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES 443
Query: 342 KAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVM 401
KAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVM
Sbjct: 444 KAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVM 503
Query: 402 DKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDAL 461
DKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDAL
Sbjct: 504 DKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDAL 563
Query: 462 SEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLS 521
SEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLS
Sbjct: 564 SEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLS 623
Query: 522 DSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPT 581
DSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPT
Sbjct: 624 DSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPT 683
Query: 582 KKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDS 641
KKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDS
Sbjct: 684 KKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDS 743
Query: 642 AKTTEETSKPKDD 654
AKTTEETSKPKDD
Sbjct: 744 AKTTEETSKPKDD 756
Score = 218 bits (554), Expect = 2e-56
Identities = 193/648 (29%), Positives = 310/648 (47%), Gaps = 63/648 (9%)
Query: 26 PKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA----ISG 81
P++A+ H + S S + +K ++ K S + AG TA +S
Sbjct: 14 PRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSA 73
Query: 82 KPG-DKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPE 140
G K + T V+++P+K S + + + + + G P+E E + +
Sbjct: 74 SSGATSKSSSMNPTETKAVKTEPEKKSQSTKL-SVVHEKKSQEGKPKEHTEPKS--LPKQ 130
Query: 141 VSDPMSS-TYIEELGKREVTIPPKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEK 199
SD S+ + ++ R P + K P D I A + G +GK +K
Sbjct: 131 ASDTGSNDAHNKKAVSRSAEQQPSEKSTEPK-TKPQDMISA-GGESVAGITAISGKPGDK 188
Query: 200 EESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASL-GTRQAEPELDLRSI 258
++ + ++ A P + K K + D AL+ L +L G + E E +
Sbjct: 189 KKEKK--------SLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTG 240
Query: 259 KEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDEL 318
EV + + +E+ G+ + TIP +YR E KP + ID L
Sbjct: 241 PEVSDPMS-STYIEELGKREVTIPPKYR----------------ELLAKPIGPDDAIDAL 283
Query: 319 SEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGT 374
S DF P+ +KTE+ ++ +E + S +++SA P + K T
Sbjct: 284 SSDFTCG----SPTAAGKKTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDT 333
Query: 375 VPDDAVEALADSLGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVK 433
+ D A+EAL+ SLG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+
Sbjct: 334 MSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPAT 393
Query: 434 DKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAIS 486
DKDGKPLLP E +E+ P SE L+D LSEDF + + + K E++K A A +S
Sbjct: 394 DKDGKPLLP-EPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVS 452
Query: 487 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 546
E V +T + Q+ APP + DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK
Sbjct: 453 EAVCRTSMCSIQS-APPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAK 511
Query: 547 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 606
E R+KLGE+++TIPP+YR + KP+ P K+S++ P + +DALS D
Sbjct: 512 EEDREKLGEKEETIPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSG 569
Query: 607 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 654
+ + AK + S+ P + +A + T ++ K DD
Sbjct: 570 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 617
Score = 81.6 bits (200), Expect = 2e-15
Identities = 83/359 (23%), Positives = 142/359 (39%), Gaps = 30/359 (8%)
Query: 299 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 356
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 357 SMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKL 416
SA A+ T ++ K E + + + V EK +E + K
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKE 120
Query: 417 GEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKF 476
+ +++P D K + + +++Q S + +G ++ + +
Sbjct: 121 HTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA 180
Query: 477 EDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKP 536
K E S TPA ++ P + + +S +D ALD L D+LG + +EN
Sbjct: 181 ISGKPGDKKKEKKSLTPAVPVES-KPDKPSGKS--GMDAALDDLIDTLGGPEETEEENTT 237
Query: 537 ME-DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQD 595
+V + + + ++LG+R+ TIPP+YR LL KP D
Sbjct: 238 YTGPEVSDPMSSTYIEELGKREVTIPPKYRELL-------------------AKPIGPDD 278
Query: 596 PIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 654
IDALS D +C S T + T K++ + + A G + +A E+ K + D
Sbjct: 279 AIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRKVEKD 332
>gi|109637763 calpastatin isoform h [Homo sapiens]
Length = 769
Score = 1275 bits (3298), Expect = 0.0
Identities = 654/686 (95%), Positives = 654/686 (95%), Gaps = 32/686 (4%)
Query: 1 MNPTETKAVKTEPEKKSQSTK-------------------PKSLPKQASDTGSNDAHNKK 41
MNPTETKAVKTEPEKKSQSTK PKSLPKQASDTGSNDAHNKK
Sbjct: 84 MNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKK 143
Query: 42 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 101
AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES
Sbjct: 144 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 203
Query: 102 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 161
KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP
Sbjct: 204 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 263
Query: 162 PKYRELLAK-------------PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 208
PKYRELLAK PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA
Sbjct: 264 PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 323
Query: 209 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 268
QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE
Sbjct: 324 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 383
Query: 269 EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK 328
EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK
Sbjct: 384 EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK 443
Query: 329 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 388
EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG
Sbjct: 444 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 503
Query: 389 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 448
KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ
Sbjct: 504 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 563
Query: 449 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 508
LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ
Sbjct: 564 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 623
Query: 509 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 568
SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL
Sbjct: 624 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 683
Query: 569 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 628
DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS
Sbjct: 684 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 743
Query: 629 SKAPKNGGKAKDSAKTTEETSKPKDD 654
SKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 744 SKAPKNGGKAKDSAKTTEETSKPKDD 769
Score = 224 bits (571), Expect = 2e-58
Identities = 195/648 (30%), Positives = 316/648 (48%), Gaps = 50/648 (7%)
Query: 26 PKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA----ISG 81
P++A+ H + S S + +K ++ K S + AG TA +S
Sbjct: 14 PRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSA 73
Query: 82 KPG-DKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPE 140
G K + T V+++P+K S + + + + + G P+E E + +
Sbjct: 74 SSGATSKSSSMNPTETKAVKTEPEKKSQSTKL-SVVHEKKSQEGKPKEHTEPKS--LPKQ 130
Query: 141 VSDPMSS-TYIEELGKREVTIPPKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEK 199
SD S+ + ++ R P + K P D I A + G +GK +K
Sbjct: 131 ASDTGSNDAHNKKAVSRSAEQQPSEKSTEPK-TKPQDMISA-GGESVAGITAISGKPGDK 188
Query: 200 EESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASL-GTRQAEPELDLRSI 258
++ + ++ A P + K K + D AL+ L +L G + E E +
Sbjct: 189 KKEKK--------SLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTG 240
Query: 259 KEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDEL 318
EV + + +E+ G+ + TIP +YR + K+G + P + KP + ID L
Sbjct: 241 PEVSDPMS-STYIEELGKREVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDAL 296
Query: 319 SEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGT 374
S DF P+ +KTE+ ++ +E + S +++SA P + K T
Sbjct: 297 SSDFTCG----SPTAAGKKTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDT 346
Query: 375 VPDDAVEALADSLGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVK 433
+ D A+EAL+ SLG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+
Sbjct: 347 MSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPAT 406
Query: 434 DKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAIS 486
DKDGKPLLP E +E+ P SE L+D LSEDF + + + K E++K A A +S
Sbjct: 407 DKDGKPLLP-EPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVS 465
Query: 487 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 546
E V +T + Q+ APP + DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK
Sbjct: 466 EAVCRTSMCSIQS-APPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAK 524
Query: 547 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 606
E R+KLGE+++TIPP+YR + KP+ P K+S++ P + +DALS D
Sbjct: 525 EEDREKLGEKEETIPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSG 582
Query: 607 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 654
+ + AK + S+ P + +A + T ++ K DD
Sbjct: 583 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 630
Score = 89.4 bits (220), Expect = 1e-17
Identities = 87/359 (24%), Positives = 148/359 (41%), Gaps = 17/359 (4%)
Query: 299 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 356
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 357 SMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKL 416
SA A+ T ++ K E + + + V EK +E + K
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKE 120
Query: 417 GEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKF 476
+ +++P D K + + +++Q S + +G ++ + +
Sbjct: 121 HTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA 180
Query: 477 EDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKP 536
K E S TPA ++ P + + +S +D ALD L D+LG + +EN
Sbjct: 181 ISGKPGDKKKEKKSLTPAVPVES-KPDKPSGKS--GMDAALDDLIDTLGGPEETEEENTT 237
Query: 537 ME-DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQD 595
+V + + + ++LG+R+ TIPP+YR LL ++ PP DS KP D
Sbjct: 238 YTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITGPPA----DSSKPIGPDD 291
Query: 596 PIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 654
IDALS D +C S T + T K++ + + A G + +A E+ K + D
Sbjct: 292 AIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRKVEKD 345
>gi|27765085 calpastatin isoform b [Homo sapiens]
Length = 686
Score = 1275 bits (3298), Expect = 0.0
Identities = 654/686 (95%), Positives = 654/686 (95%), Gaps = 32/686 (4%)
Query: 1 MNPTETKAVKTEPEKKSQSTK-------------------PKSLPKQASDTGSNDAHNKK 41
MNPTETKAVKTEPEKKSQSTK PKSLPKQASDTGSNDAHNKK
Sbjct: 1 MNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKK 60
Query: 42 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 101
AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES
Sbjct: 61 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 120
Query: 102 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 161
KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP
Sbjct: 121 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 180
Query: 162 PKYRELLAK-------------PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 208
PKYRELLAK PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA
Sbjct: 181 PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 240
Query: 209 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 268
QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE
Sbjct: 241 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 300
Query: 269 EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK 328
EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK
Sbjct: 301 EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK 360
Query: 329 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 388
EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG
Sbjct: 361 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 420
Query: 389 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 448
KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ
Sbjct: 421 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 480
Query: 449 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 508
LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ
Sbjct: 481 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 540
Query: 509 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 568
SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL
Sbjct: 541 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 600
Query: 569 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 628
DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS
Sbjct: 601 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 660
Query: 629 SKAPKNGGKAKDSAKTTEETSKPKDD 654
SKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 661 SKAPKNGGKAKDSAKTTEETSKPKDD 686
>gi|109637761 calpastatin isoform g [Homo sapiens]
Length = 772
Score = 1273 bits (3295), Expect = 0.0
Identities = 654/689 (94%), Positives = 654/689 (94%), Gaps = 35/689 (5%)
Query: 1 MNPTETKA----------------------VKTEPEKKSQSTKPKSLPKQASDTGSNDAH 38
MNPTETKA VKTEPEKKSQSTKPKSLPKQASDTGSNDAH
Sbjct: 84 MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKPKSLPKQASDTGSNDAH 143
Query: 39 NKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVP 98
NKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVP
Sbjct: 144 NKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVP 203
Query: 99 VESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREV 158
VESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREV
Sbjct: 204 VESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREV 263
Query: 159 TIPPKYRELLAK-------------PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEV 205
TIPPKYRELLAK PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEV
Sbjct: 264 TIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEV 323
Query: 206 LKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAK 265
LKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAK
Sbjct: 324 LKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAK 383
Query: 266 AKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRS 325
AKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRS
Sbjct: 384 AKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRS 443
Query: 326 ECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALAD 385
ECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALAD
Sbjct: 444 ECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALAD 503
Query: 386 SLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES 445
SLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES
Sbjct: 504 SLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES 563
Query: 446 KEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD 505
KEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD
Sbjct: 564 KEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD 623
Query: 506 TSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYR 565
TSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYR
Sbjct: 624 TSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYR 683
Query: 566 HLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKA 625
HLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKA
Sbjct: 684 HLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKA 743
Query: 626 ASSSKAPKNGGKAKDSAKTTEETSKPKDD 654
ASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 744 ASSSKAPKNGGKAKDSAKTTEETSKPKDD 772
Score = 223 bits (569), Expect = 3e-58
Identities = 193/652 (29%), Positives = 310/652 (47%), Gaps = 71/652 (10%)
Query: 40 KKAVSRSAEQQPSEKSTEPKTKPQD-------------------MISAGGESVAGITAIS 80
+ A +R + SEK++E +KP + + G S ++A S
Sbjct: 16 RAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASS 75
Query: 81 GKPGDKKKEKKSLTPAVPVESK---PDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYT 137
G + T A+PV + P P+ K A+ PE+ + +
Sbjct: 76 GATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKT------EPEKKSQSTKPKS 129
Query: 138 GPEVSDPMSS--TYIEELGKREVTIPPKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGK 195
P+ + S + ++ R P + K P D I A + G +GK
Sbjct: 130 LPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPK-TKPQDMISA-GGESVAGITAISGK 187
Query: 196 KTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASL-GTRQAEPELD 254
+K++ + ++ A P + K K + D AL+ L +L G + E E
Sbjct: 188 PGDKKKEKK--------SLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENT 239
Query: 255 LRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESEL 314
+ EV + + +E+ G+ + TIP +YR + K+G + P + KP +
Sbjct: 240 TYTGPEVSDPMS-STYIEELGKREVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDA 295
Query: 315 IDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPAT 370
ID LS DF P+ +KTE+ ++ +E + S +++SA P +
Sbjct: 296 IDALSSDFTCG----SPTAAGKKTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKV 345
Query: 371 LKGTVPDDAVEALADSLGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRL 429
K T+ D A+EAL+ SLG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL
Sbjct: 346 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 405
Query: 430 EEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA-- 482
+ DKDGKPLLP E +E+ P SE L+D LSEDF + + + K E++K A
Sbjct: 406 KPATDKDGKPLLP-EPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 464
Query: 483 AAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVK 542
A +SE V +T + Q+ APP + DDA++ L+DSLG+++ DP++ KP+ DKVK
Sbjct: 465 APVSEAVCRTSMCSIQS-APPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVK 523
Query: 543 EKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSG 602
EKAK E R+KLGE+++TIPP+YR + KP+ P K+S++ P + +DALS
Sbjct: 524 EKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSE 581
Query: 603 DLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 654
D + + AK + S+ P + +A + T ++ K DD
Sbjct: 582 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 633
Score = 81.3 bits (199), Expect = 3e-15
Identities = 90/364 (24%), Positives = 153/364 (42%), Gaps = 24/364 (6%)
Query: 299 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 356
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 357 SMCSIQSAPPEPATLKGTVPDDAV---EALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 413
SA A+ T ++ E A + ++ P P K K++A + +
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPH--LPNKKKHKKQAVKTEP 118
Query: 414 EKLGE--KEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNA 471
EK + K +++P D K + + +++Q S + +G ++
Sbjct: 119 EKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESV 178
Query: 472 SSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDP 531
+ + K E S TPA ++ P + + +S +D ALD L D+LG +
Sbjct: 179 AGITAISGKPGDKKKEKKSLTPAVPVES-KPDKPSGKS--GMDAALDDLIDTLGGPEETE 235
Query: 532 DENKPME-DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKP 590
+EN +V + + + ++LG+R+ TIPP+YR LL ++ PP DS KP
Sbjct: 236 EENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITGPPA----DSSKP 289
Query: 591 ADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSK 650
D IDALS D +C S T + T K++ + + A G + +A E+ K
Sbjct: 290 IGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRK 344
Query: 651 PKDD 654
+ D
Sbjct: 345 VEKD 348
>gi|109637765 calpastatin isoform i [Homo sapiens]
Length = 708
Score = 1262 bits (3265), Expect = 0.0
Identities = 654/708 (92%), Positives = 654/708 (92%), Gaps = 54/708 (7%)
Query: 1 MNPTETKA----------------------VKTEPEKKSQSTK----------------- 21
MNPTETKA VKTEPEKKSQSTK
Sbjct: 1 MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEH 60
Query: 22 --PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 79
PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI
Sbjct: 61 TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 120
Query: 80 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 139
SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP
Sbjct: 121 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 180
Query: 140 EVSDPMSSTYIEELGKREVTIPPKYRELLAK-------------PIGPDDAIDALSSDFT 186
EVSDPMSSTYIEELGKREVTIPPKYRELLAK PIGPDDAIDALSSDFT
Sbjct: 181 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 240
Query: 187 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 246
CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT
Sbjct: 241 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 300
Query: 247 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 306
RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP
Sbjct: 301 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 360
Query: 307 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 366
KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP
Sbjct: 361 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 420
Query: 367 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 426
EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD
Sbjct: 421 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 480
Query: 427 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 486
YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS
Sbjct: 481 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 540
Query: 487 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 546
EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK
Sbjct: 541 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 600
Query: 547 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 606
AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS
Sbjct: 601 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 660
Query: 607 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 654
CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 661 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 708
>gi|109637753 calpastatin isoform a [Homo sapiens]
Length = 791
Score = 1262 bits (3265), Expect = 0.0
Identities = 654/708 (92%), Positives = 654/708 (92%), Gaps = 54/708 (7%)
Query: 1 MNPTETKA----------------------VKTEPEKKSQSTK----------------- 21
MNPTETKA VKTEPEKKSQSTK
Sbjct: 84 MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEH 143
Query: 22 --PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 79
PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI
Sbjct: 144 TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 203
Query: 80 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 139
SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP
Sbjct: 204 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 263
Query: 140 EVSDPMSSTYIEELGKREVTIPPKYRELLAK-------------PIGPDDAIDALSSDFT 186
EVSDPMSSTYIEELGKREVTIPPKYRELLAK PIGPDDAIDALSSDFT
Sbjct: 264 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 323
Query: 187 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 246
CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT
Sbjct: 324 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 383
Query: 247 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 306
RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP
Sbjct: 384 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 443
Query: 307 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 366
KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP
Sbjct: 444 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 503
Query: 367 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 426
EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD
Sbjct: 504 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 563
Query: 427 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 486
YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS
Sbjct: 564 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 623
Query: 487 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 546
EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK
Sbjct: 624 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 683
Query: 547 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 606
AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS
Sbjct: 684 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 743
Query: 607 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 654
CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 744 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 791
Score = 219 bits (559), Expect = 5e-57
Identities = 195/665 (29%), Positives = 314/665 (47%), Gaps = 78/665 (11%)
Query: 40 KKAVSRSAEQQPSEKSTEPKTKPQD-------------------MISAGGESVAGITAIS 80
+ A +R + SEK++E +KP + + G S ++A S
Sbjct: 16 RAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASS 75
Query: 81 GKPGDKKKEKKSLTPAVPVESK---PDKPSGKSGMDAAL---------DDLIDTLGGPEE 128
G + T A+PV + P P+ K A+ + + +
Sbjct: 76 GATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKS 135
Query: 129 TEEENTTYTGP-----EVSDPMSS-TYIEELGKREVTIPPKYRELLAKPIGPDDAIDALS 182
E + +T P + SD S+ + ++ R P + K P D I A
Sbjct: 136 QEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPK-TKPQDMISA-G 193
Query: 183 SDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSA 242
+ G +GK +K++ + ++ A P + K K + D AL+ L
Sbjct: 194 GESVAGITAISGKPGDKKKEKK--------SLTPAVPVESKPDKPSGKSGMDAALDDLID 245
Query: 243 SL-GTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPE 301
+L G + E E + EV + + +E+ G+ + TIP +YR + K+G +
Sbjct: 246 TLGGPEETEEENTTYTGPEVSDPMS-STYIEELGKREVTIPPKYR-ELLAKKEG--ITGP 301
Query: 302 PEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSI 361
P + KP + ID LS DF P+ +KTE+ ++ +E + S ++
Sbjct: 302 PADSSKPIGPDDAIDALSSDFTCG----SPTAAGKKTEKEES------TEVLKAQSAGTV 351
Query: 362 QSAPP----EPATLKGTVPDDAVEALADSLGKKEADPE-DGKPVMDKVKEKAKEEDREKL 416
+SA P + K T+ D A+EAL+ SLG ++A+PE D + + + + KAKEE EK
Sbjct: 352 RSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKC 411
Query: 417 GEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQ-----NA 471
GE +ETIP +YRL+ DKDGKPLLP E +E+ P SE L+D LSEDF + +
Sbjct: 412 GEDDETIPSEYRLKPATDKDGKPLLP-EPEEKPKPRSESELIDELSEDFDRSECKEKPSK 470
Query: 472 SSLKFEDAKLA--AAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQP 529
+ K E++K A A +SE V +T + Q+ APP + DDA++ L+DSLG+++
Sbjct: 471 PTEKTEESKAAAPAPVSEAVCRTSMCSIQS-APPEPATLKGTVPDDAVEALADSLGKKEA 529
Query: 530 DPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKK 589
DP++ KP+ DKVKEKAK E R+KLGE+++TIPP+YR + KP+ P K+S++
Sbjct: 530 DPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLP--KESKEQLP 587
Query: 590 PADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETS 649
P + +DALS D + + AK + S+ P + +A + T ++
Sbjct: 588 PMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSD 647
Query: 650 KPKDD 654
K DD
Sbjct: 648 KDLDD 652
Score = 80.9 bits (198), Expect = 3e-15
Identities = 100/387 (25%), Positives = 162/387 (41%), Gaps = 51/387 (13%)
Query: 299 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 356
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 357 SMCSIQSAPPEPATLKGTVPDDAV---EALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 413
SA A+ T ++ E A + ++ P P K K++A + +
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPH--LPNKKKHKKQAVKTEP 118
Query: 414 EKLGEKEETIPPDYRLEEVKDKDGKP-------LLPKE----------SKEQLPPMSEDF 456
EK + + + E K ++GKP LPK+ +K+ + +E
Sbjct: 119 EKKSQSTKLSV----VHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQ 174
Query: 457 LLDALSEDFSGPQNASSLKFEDAKLAAAIS--------EVVSQTPASTTQAGAPPRDTSQ 508
+ +E + PQ+ S E AIS E S TPA ++ P + + +
Sbjct: 175 PSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES-KPDKPSGK 233
Query: 509 SDKDLDDALDKLSDSLGQRQPDPDENKPME-DKVKEKAKAEHRDKLGERDDTIPPEYRHL 567
S +D ALD L D+LG + +EN +V + + + ++LG+R+ TIPP+YR L
Sbjct: 234 S--GMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYREL 291
Query: 568 LDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAAS 627
L ++ PP DS KP D IDALS D +C S T + T K++ +
Sbjct: 292 LAK--KEGITGPPA----DSSKPIGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLK 344
Query: 628 SSKAPKNGGKAKDSAKTTEETSKPKDD 654
+ A G + +A E+ K + D
Sbjct: 345 AQSA----GTVRSAAPPQEKKRKVEKD 367
>gi|27765087 calpastatin isoform c [Homo sapiens]
Length = 430
Score = 781 bits (2017), Expect = 0.0
Identities = 391/393 (99%), Positives = 392/393 (99%), Gaps = 1/393 (0%)
Query: 262 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 321
D+AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED
Sbjct: 39 DQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 98
Query: 322 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 381
FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE
Sbjct: 99 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 158
Query: 382 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 441
ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL
Sbjct: 159 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 218
Query: 442 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 501
PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA
Sbjct: 219 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 278
Query: 502 PPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 561
PPRDTS SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP
Sbjct: 279 PPRDTS-SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 337
Query: 562 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 621
PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK
Sbjct: 338 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 397
Query: 622 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 654
CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 398 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
Score = 200 bits (508), Expect = 4e-51
Identities = 142/396 (35%), Positives = 207/396 (52%), Gaps = 43/396 (10%)
Query: 150 IEELGKREVTIPPKYR----------------ELLAKPIGPDDAIDALSSDFTCGSPTAA 193
+E+ G+ + TIP +YR E KP + ID LS DF
Sbjct: 48 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSE--CK 105
Query: 194 GKKTEKEESTEVLKAQSAGTVRSA-----------APPQEKKRKVEKDTMSDQALEALSA 242
K ++ E TE KA + V A APP+ K T+ D A+EAL+
Sbjct: 106 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLK---GTVPDDAVEALAD 162
Query: 243 SLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-E 301
SLG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E
Sbjct: 163 SLGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKE 221
Query: 302 PEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSI 361
+E+ P SE L+D LSEDF + + + K E++K A A +SE V +T +
Sbjct: 222 SKEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTT 274
Query: 362 QSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEE 421
Q+ P T DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++
Sbjct: 275 QAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDD 334
Query: 422 TIPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDA 479
TIPP+YR + KP+ P K+S++ P + +DALS D + + A
Sbjct: 335 TIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTA 394
Query: 480 KLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 515
K + S+ P + +A + T ++ K DD
Sbjct: 395 KDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
Score = 115 bits (288), Expect = 1e-25
Identities = 98/301 (32%), Positives = 144/301 (47%), Gaps = 44/301 (14%)
Query: 82 KPGDKKKEKKSLTPA-----------VPVESKPDKPSGKSGM--DAALDDLIDTLGGPEE 128
KP +K +E K+ PA ++S P +P+ G D A++ L D+LG +E
Sbjct: 110 KPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG-KKE 168
Query: 129 TEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYR----------ELLAK-------P 171
+ E+ +V + E+LG++E TIPP YR LL K P
Sbjct: 169 ADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPP 228
Query: 172 IGPDDAIDALSSDFTCGSPTAAGKKTEKEE----STEVLKAQSAGTVRSAAPPQEKKRKV 227
+ D +DALS DF+ G A+ K E + +EV+ A T ++ APP R
Sbjct: 229 MSEDFLLDALSEDFS-GPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPP----RDT 283
Query: 228 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 287
D D AL+ LS SLG RQ +P+ + + +++ + KAK E +K GE D+TIP EYR
Sbjct: 284 SSDKDLDDALDKLSDSLGQRQPDPD-ENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRH 342
Query: 288 ---KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAA 344
DK KP + E+ KP + + ID LS D D + S+ T K + KAA
Sbjct: 343 LLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAA 402
Query: 345 A 345
+
Sbjct: 403 S 403
Score = 63.5 bits (153), Expect = 6e-10
Identities = 62/256 (24%), Positives = 106/256 (41%), Gaps = 29/256 (11%)
Query: 1 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
M+ + KA + + EK + K +++P D K + + +++Q S +
Sbjct: 178 MDKVKEKAKEEDREKLGE--KEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLL 235
Query: 61 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES--KPDKPSGKSGMDAALDD 118
+G ++ + + K E S TPA ++ P S +D ALD
Sbjct: 236 DALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDK 295
Query: 119 LIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELL---------- 168
L D+LG + +EN +V + + + ++LG+R+ TIPP+YR LL
Sbjct: 296 LSDSLGQRQPDPDENKPMED-KVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVK 354
Query: 169 ---------AKPIGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTV 214
KP D IDALS D +C S T + T K++ + + A G
Sbjct: 355 PPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKA 414
Query: 215 RSAAPPQEKKRKVEKD 230
+ +A E+ K + D
Sbjct: 415 KDSAKTTEETSKPKDD 430
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 90.9 bits (224), Expect = 3e-18
Identities = 136/590 (23%), Positives = 221/590 (37%), Gaps = 58/590 (9%)
Query: 95 PAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELG 154
P +P S K + + +T+ E+TEE T EV++ EE G
Sbjct: 427 PKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVT---EEVTEEEEKEAKEEEG 483
Query: 155 KREVTIPPKYRELLAKPIGPDDAIDALSSDFTCGSPT-------AAGKKTEKEESTEVLK 207
K E + E + A +A S + SP A K EKEE+ +
Sbjct: 484 KEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAE 543
Query: 208 AQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAK 267
+S +S A + K K ++A + P + K EAK+
Sbjct: 544 VKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKE--EAKSPAEAKSP 601
Query: 268 EEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSEC 327
E+ E+ ++ P+E + + + PE+ P E E ++ ++ E
Sbjct: 602 EKAKSPVKEEAKS-PAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEA 660
Query: 328 K--EKPSKPTEKTEESKAAAPAPV-SEAVCRTSMCS-IQSAPPEPATLKGTVPDDAVEA- 382
K EK P + +S A +PV +EA S ++ P K V ++A
Sbjct: 661 KSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPE 720
Query: 383 LADSLGKKEAD-PEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 441
A S K+EA PE K VKE+AK ++ K EK +T+ +VK + K
Sbjct: 721 KAKSPVKEEAKTPEKAK---SPVKEEAKSPEKAKSPEKAKTL-------DVKSPEAKTPA 770
Query: 442 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAA--------AISEVVSQTP 493
+E++ E + E+ P+ A S EDAK S V +
Sbjct: 771 KEEARSPADKFPEK-AKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK 829
Query: 494 ASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKA-------K 546
+ PP+ + ++ DS + P + KP ++ KE A K
Sbjct: 830 PQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESK 889
Query: 547 AEHRDKLGERDDTIP-PEYRHLLDDNGQDKPVKPPTKKSEDSKKPAD--DQDPIDALSGD 603
E + + E +P PE ++ P K K+ K+ + ++P DA + +
Sbjct: 890 VEAKKEEAEDKKKVPTPE---------KEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE 940
Query: 604 LDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKT-TEETSKPK 652
E + K +KA + PK KAK+ KT ++E SKPK
Sbjct: 941 PSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPK 990
Score = 84.0 bits (206), Expect = 4e-16
Identities = 110/473 (23%), Positives = 188/473 (39%), Gaps = 46/473 (9%)
Query: 206 LKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAK 265
+K +S ++ +++ VE+ T Q E ++ E E E +EA+
Sbjct: 436 IKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAE 495
Query: 266 AKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRS 325
EE+ + ++ P + P ++ P + EK + +S +E+ S + +S
Sbjct: 496 GGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEV---KSPEKAKS 552
Query: 326 ECKEKPSKPTE--KTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDA 379
KE+ P E E+ +A +PA V S ++ P P K V ++A
Sbjct: 553 PAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEA 612
Query: 380 VE-ALADSLGKKEA-------DPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEE 431
A A S K+EA PE K KE+AK ++ K EKEE P+
Sbjct: 613 KSPAEAKSPVKEEAKSPAEVKSPEKAK---SPTKEEAKSPEKAKSPEKEEAKSPEKAKSP 669
Query: 432 VKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQ 491
VK + P K S + S + + E+ P+ A S E+AK V +
Sbjct: 670 VKAEAKSPEKAK-SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE 728
Query: 492 TPASTTQAGAPPRDTSQSD---------KDLDDALDKLSDSLGQRQPDPDENKPMEDK-- 540
+ +A +P ++ ++S K LD + + P + P + K
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP 788
Query: 541 VKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDAL 600
VKE+ K+ + K ++D PE + + + VK P K+ E ++ + P A
Sbjct: 789 VKEEVKSPEKAKSPLKEDAKAPE-----KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA- 842
Query: 601 SGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKD 653
+ + P+T +T + KD K+ A +AP K K K KPK+
Sbjct: 843 --EEEKAPATPKTEEK--KDSKKEEAPKKEAP----KPKVEEKKEPAVEKPKE 887
Score = 79.0 bits (193), Expect = 1e-14
Identities = 135/598 (22%), Positives = 220/598 (36%), Gaps = 67/598 (11%)
Query: 6 TKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDM 65
T+ V E EK+++ + K + + + + P+E++ P+ + +
Sbjct: 467 TEEVTEEEEKEAKEEEGK-------EEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSP 519
Query: 66 ISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESK-PDKPSGKSGMDAALDDLIDTLG 124
+ +S A K +K++ K P ++K P K KS +A + +
Sbjct: 520 VKEEAKSPA-----EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKS 574
Query: 125 GPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDDAIDA-LSS 183
E E E + + E K V K P+ + A + S
Sbjct: 575 PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKS 634
Query: 184 DFTCGSPTAA-GKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSA 242
SPT K EK +S E +A+S +S + K + K + +A A
Sbjct: 635 PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 243 SLGTRQA--EPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 300
++ PE +KE EAK+ E+ E+ +T E P ++ P
Sbjct: 695 KSPVKEEAKSPEKAKSPVKE--EAKSPEKAKSPVKEEAKT--PEKAKSPVKEEAKSP--- 747
Query: 301 EPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCS 360
EK K +++ +D S + ++ KE+ P +K E A +PV E V
Sbjct: 748 ---EKAKSPEKAKTLDVKSPEA-KTPAKEEARSPADKFPEK---AKSPVKEEV------- 793
Query: 361 IQSAPPEPATLKGTVPDDAVEALADSLGKKEADP----EDGKPVMDKVKEKAKEEDREKL 416
P K + +DA +A + KKE E+ KP KVKE K+ + EK
Sbjct: 794 -----KSPEKAKSPLKEDA-KAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA 847
Query: 417 GEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKF 476
P + EE KD K PK KE P E+ A+ + A +
Sbjct: 848 -------PATPKTEEKKDSK-KEEAPK--KEAPKPKVEEKKEPAVEKPKESKVEAKKEEA 897
Query: 477 EDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKP 536
ED K E + + P T + K+ DDA K +++ E K
Sbjct: 898 EDKKKVPT-PEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKD 956
Query: 537 M--------EDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSED 586
E+K K +AKA+ DK ++ + P + + K KPP K +ED
Sbjct: 957 TKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATED 1014
Score = 76.6 bits (187), Expect = 7e-14
Identities = 98/465 (21%), Positives = 178/465 (38%), Gaps = 42/465 (9%)
Query: 2 NPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTK 61
+P + +A K+ PE KS + P + + K+ AE + EK+ P
Sbjct: 552 SPAKEEA-KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPV-- 608
Query: 62 PQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLID 121
++ + E+ + + + P + K +K+ +P P+K +A +
Sbjct: 609 -KEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAK 667
Query: 122 TLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPI-GPDDAIDA 180
+ E E P ++ S + K E P K + + + P+ A
Sbjct: 668 SPVKAEAKSPEKAK--SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725
Query: 181 LSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEAL 240
+ + + K E + + + A T+ +P + K E + +D+ E
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA 785
Query: 241 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGE-----DDETIPSEYRLKPATDK-- 293
+ + PE +KE +AKA E+++ K E +E P E ++K K
Sbjct: 786 KSPVKEEVKSPEKAKSPLKE--DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAE 843
Query: 294 -DGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEA 352
+ P P+ EEK + E + ++ + + +EK EK +ESK
Sbjct: 844 EEKAPATPKTEEKKDSKKE----EAPKKEAPKPKVEEKKEPAVEKPKESKV--------- 890
Query: 353 VCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEED 412
A E A K VP EA A K++A P++ V K + AK ++
Sbjct: 891 ----------EAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE 940
Query: 413 REKLGEKEETIP--PDYRLEEVKDKDGKPLLPKESKEQLPPMSED 455
K EK+E P D + E+ K + KP ++KE +S++
Sbjct: 941 PSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE 985
Score = 58.2 bits (139), Expect = 2e-08
Identities = 81/372 (21%), Positives = 143/372 (38%), Gaps = 51/372 (13%)
Query: 2 NPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTK 61
+P + +A E K + KS K S +KA S E+ S + + K
Sbjct: 668 SPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK 727
Query: 62 PQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDA----ALD 117
+ +S A S + ++ K+L P P K +S D A
Sbjct: 728 EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKS 787
Query: 118 DLIDTLGGPEETE---EENTTYTGPEV--SDPMSSTYIEELGKREVTI--PPKYRELLAK 170
+ + + PE+ + +E+ E+ + + S EE +EV + PPK E
Sbjct: 788 PVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA 847
Query: 171 PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKD 230
P +P KK K+E +A P EK ++ + +
Sbjct: 848 P----------------ATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE 891
Query: 231 TMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPA 290
++A + ++A +++++ ++AK KE K E ++ + ++ KPA
Sbjct: 892 AKKEEAEDKKKVPTPEKEAPAKVEVK-----EDAKPKE-KTEVAKKEPDDAKAKEPSKPA 945
Query: 291 TDKDGKP--------LLPEPEEKPKPRSESELIDE-LSEDFDR---------SECKEKPS 332
K+ P +PEEKPK ++++ D+ LS++ + S +K S
Sbjct: 946 EKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDS 1005
Query: 333 KPTEKTEESKAA 344
KP EK E KAA
Sbjct: 1006 KPPEKATEDKAA 1017
Score = 47.8 bits (112), Expect = 3e-05
Identities = 59/270 (21%), Positives = 103/270 (38%), Gaps = 46/270 (17%)
Query: 396 DGKPVMDKVKE--KAKEEDREKLGEK--------EETIPPDYRLEEVKDKDGKPLLPKES 445
+G P + V K K E++ K+ EK EE EEV +++ K +E
Sbjct: 424 EGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEG 483
Query: 446 KEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD 505
KE+ E E G + S E+A + +A +P ++
Sbjct: 484 KEEEGGEEE--------EAEGGEEETKSPPAEEAA-------------SPEKEAKSPVKE 522
Query: 506 TSQSDKDLDDALDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLGERDDTIPPEY 564
++S + + P+ +E K P E K EKAK+ +++ + PE
Sbjct: 523 EAKSPAEA-------------KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEK 569
Query: 565 RHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKK 624
P K + E++K PA+ + P A S + S E +++ K++ K
Sbjct: 570 EEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE-AKSPVKEEAKS 628
Query: 625 AASSSKAPKNGGKAKDSAKTTEETSKPKDD 654
A K K+ AK+ E+ P+ +
Sbjct: 629 PAEVKSPEKAKSPTKEEAKSPEKAKSPEKE 658
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 67.0 bits (162), Expect = 5e-11
Identities = 101/401 (25%), Positives = 155/401 (38%), Gaps = 65/401 (16%)
Query: 192 AAGKKTEKEESTEVLKAQSAGTVRSAAPP-------------QEKKRKVEKDTMSDQALE 238
AA +K E+ E+ E A V++ AP QE++ + ++ SDQA E
Sbjct: 491 AAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE 550
Query: 239 ALSASLGT------RQAEPELDLRSIKEVDEAK---AKEEKLEKCGEDDETIPSEYRLKP 289
S G+ Q E E + + E EAK EEK E+ +E + KP
Sbjct: 551 GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP 610
Query: 290 ATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTE-ESKAAAPAP 348
K P P E+ P +S + ++ +S +EK P K+ E K +P
Sbjct: 611 EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV- 669
Query: 349 VSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALAD--SLGKKEADPEDGKPVMDKVKE 406
S P K VP VE +GK E E+ K +VKE
Sbjct: 670 --------------SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK----EVKE 711
Query: 407 KAKEEDREKLGEKEETIPPDYRLEE-VKD----------KDGKPLLPKESKEQLPPMSED 455
KEE EK EK + +P + E VK+ K K L KE+KE+ P+ ++
Sbjct: 712 APKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQE 771
Query: 456 FLLDAL-----SEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSD 510
+ SE+ + A + ED + + E + T + G+ +
Sbjct: 772 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEV-EGKEEVEQETKEKGS---GREEEK 827
Query: 511 KDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRD 551
+ + LD LS + ++ D E K + K EK +E D
Sbjct: 828 GVVTNGLD-LSPADEKKGGDKSEEKVVVTKTVEKITSEGGD 867
Score = 48.5 bits (114), Expect = 2e-05
Identities = 89/391 (22%), Positives = 138/391 (35%), Gaps = 52/391 (13%)
Query: 179 DALSSDFTCGSPTAAGKKTEKEESTE--VLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQA 236
D L+ AA +K + E T G + + PP K++K +
Sbjct: 386 DLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPK 445
Query: 237 LEAL---------SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 287
L+ + ++E E L +I E KEEK E E +E +E
Sbjct: 446 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEE 505
Query: 288 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEK---------- 337
A K PE +E+ + E E +E E+ + ++ + +EK
Sbjct: 506 VAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGE 565
Query: 338 TEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDG 397
EE + A A EA + ++ E AT + V D VE +K P
Sbjct: 566 QEEGETEAEAEGEEAEAKEEK-KVEEKSEEVATKEELVADAKVEK-----PEKAKSPVPK 619
Query: 398 KPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFL 457
PV +K K + E EK ++ P +EE K K P P E K + P
Sbjct: 620 SPVEEKGKSPVPKSPVE---EKGKSPVPKSPVEE-KGKSPVPKSPVEEKGKSPVSK---- 671
Query: 458 LDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDAL 517
+ E P S + E+AK A + + Q + P++ K+
Sbjct: 672 -SPVEEKAKSPVPKSPV--EEAKSKAEVGK-GEQKEEEEKEVKEAPKEEKVEKKE----- 722
Query: 518 DKLSDSLGQRQPDPDENKPMEDKVKEKAKAE 548
++ D E K E VKE+A AE
Sbjct: 723 --------EKPKDVPEKKKAESPVKEEAVAE 745
Score = 33.5 bits (75), Expect = 0.63
Identities = 60/305 (19%), Positives = 115/305 (37%), Gaps = 51/305 (16%)
Query: 12 EPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTK---------- 61
E E +++ + ++ ++ + S + K+ + A+ + EK+ P K
Sbjct: 570 ETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSP 629
Query: 62 -PQDMISAGGESVAGITAISGK-----PGDKKKEK-KSLTPAVPVESKPDKPSGKSGMDA 114
P+ + G+S + + K P +EK KS PVE K P KS ++
Sbjct: 630 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEE 689
Query: 115 ALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGP 174
A +G E+ EEE ++EV PK ++ K P
Sbjct: 690 AKSKA--EVGKGEQKEEE----------------------EKEVKEAPKEEKVEKKEEKP 725
Query: 175 DDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD 234
D + ++ SP E T+ +K + P +++++ EK +
Sbjct: 726 KDVPEKKKAE----SPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEK-AGGE 780
Query: 235 QALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG----EDDETIPSEYRLKPA 290
E + G + + E D+ EV+ + E++ ++ G E+ + + L PA
Sbjct: 781 GGSEEEGSDKGAKGSRKE-DIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPA 839
Query: 291 TDKDG 295
+K G
Sbjct: 840 DEKKG 844
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 67.0 bits (162), Expect = 5e-11
Identities = 101/401 (25%), Positives = 155/401 (38%), Gaps = 65/401 (16%)
Query: 192 AAGKKTEKEESTEVLKAQSAGTVRSAAPP-------------QEKKRKVEKDTMSDQALE 238
AA +K E+ E+ E A V++ AP QE++ + ++ SDQA E
Sbjct: 115 AAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE 174
Query: 239 ALSASLGT------RQAEPELDLRSIKEVDEAK---AKEEKLEKCGEDDETIPSEYRLKP 289
S G+ Q E E + + E EAK EEK E+ +E + KP
Sbjct: 175 GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP 234
Query: 290 ATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTE-ESKAAAPAP 348
K P P E+ P +S + ++ +S +EK P K+ E K +P
Sbjct: 235 EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV- 293
Query: 349 VSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALAD--SLGKKEADPEDGKPVMDKVKE 406
S P K VP VE +GK E E+ K +VKE
Sbjct: 294 --------------SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK----EVKE 335
Query: 407 KAKEEDREKLGEKEETIPPDYRLEE-VKD----------KDGKPLLPKESKEQLPPMSED 455
KEE EK EK + +P + E VK+ K K L KE+KE+ P+ ++
Sbjct: 336 APKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQE 395
Query: 456 FLLDAL-----SEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSD 510
+ SE+ + A + ED + + E + T + G+ +
Sbjct: 396 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEV-EGKEEVEQETKEKGS---GREEEK 451
Query: 511 KDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRD 551
+ + LD LS + ++ D E K + K EK +E D
Sbjct: 452 GVVTNGLD-LSPADEKKGGDKSEEKVVVTKTVEKITSEGGD 491
Score = 48.5 bits (114), Expect = 2e-05
Identities = 89/391 (22%), Positives = 138/391 (35%), Gaps = 52/391 (13%)
Query: 179 DALSSDFTCGSPTAAGKKTEKEESTE--VLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQA 236
D L+ AA +K + E T G + + PP K++K +
Sbjct: 10 DLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPK 69
Query: 237 LEAL---------SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 287
L+ + ++E E L +I E KEEK E E +E +E
Sbjct: 70 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEE 129
Query: 288 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEK---------- 337
A K PE +E+ + E E +E E+ + ++ + +EK
Sbjct: 130 VAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGE 189
Query: 338 TEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDG 397
EE + A A EA + ++ E AT + V D VE +K P
Sbjct: 190 QEEGETEAEAEGEEAEAKEEK-KVEEKSEEVATKEELVADAKVEK-----PEKAKSPVPK 243
Query: 398 KPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFL 457
PV +K K + E EK ++ P +EE K K P P E K + P
Sbjct: 244 SPVEEKGKSPVPKSPVE---EKGKSPVPKSPVEE-KGKSPVPKSPVEEKGKSPVSK---- 295
Query: 458 LDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDAL 517
+ E P S + E+AK A + + Q + P++ K+
Sbjct: 296 -SPVEEKAKSPVPKSPV--EEAKSKAEVGK-GEQKEEEEKEVKEAPKEEKVEKKE----- 346
Query: 518 DKLSDSLGQRQPDPDENKPMEDKVKEKAKAE 548
++ D E K E VKE+A AE
Sbjct: 347 --------EKPKDVPEKKKAESPVKEEAVAE 369
Score = 33.5 bits (75), Expect = 0.63
Identities = 60/305 (19%), Positives = 115/305 (37%), Gaps = 51/305 (16%)
Query: 12 EPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTK---------- 61
E E +++ + ++ ++ + S + K+ + A+ + EK+ P K
Sbjct: 194 ETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSP 253
Query: 62 -PQDMISAGGESVAGITAISGK-----PGDKKKEK-KSLTPAVPVESKPDKPSGKSGMDA 114
P+ + G+S + + K P +EK KS PVE K P KS ++
Sbjct: 254 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEE 313
Query: 115 ALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGP 174
A +G E+ EEE ++EV PK ++ K P
Sbjct: 314 AKSKA--EVGKGEQKEEE----------------------EKEVKEAPKEEKVEKKEEKP 349
Query: 175 DDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD 234
D + ++ SP E T+ +K + P +++++ EK +
Sbjct: 350 KDVPEKKKAE----SPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEK-AGGE 404
Query: 235 QALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG----EDDETIPSEYRLKPA 290
E + G + + E D+ EV+ + E++ ++ G E+ + + L PA
Sbjct: 405 GGSEEEGSDKGAKGSRKE-DIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPA 463
Query: 291 TDKDG 295
+K G
Sbjct: 464 DEKKG 468
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 66.6 bits (161), Expect = 7e-11
Identities = 166/746 (22%), Positives = 266/746 (35%), Gaps = 126/746 (16%)
Query: 3 PTETKAVKTEPEKKSQSTKPKSLPKQASDT----GSNDAHNKKAVSRSAEQQPSEKSTEP 58
P + +V +E +K + PK T S+ A K + S Q +E+ T P
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
Query: 59 -----KTKPQDMISAGGESVAGIT--AISGKPGDKK--------KEKKSLTPAVPVESKP 103
KP GE V+ AI D K E K PV+ K
Sbjct: 794 PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE 853
Query: 104 DKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKR------E 157
+ ++ M D G P T G V P S +E +R
Sbjct: 854 EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA--GQTVPTPQQSPKPQEQSRRFSLNLGS 911
Query: 158 VTIPPKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSA 217
+T PK ++P P + + F G + S + A G +
Sbjct: 912 ITDAPK-----SQPTTPQETVTGKLFGF--------GASIFSQASNLISTAGQPGPHSQS 958
Query: 218 APPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE-EKLEKCGE 276
P K+ Q + T QA P +SI E KA EKLE E
Sbjct: 959 GPGAPMKQA----PAPSQPPTSQGPPKSTGQAPPA-PAKSIPVKKETKAPAAEKLEPKAE 1013
Query: 277 DDETIP-SEYRLKPATDKDGKPLLPEP---------EEKPKPRSESELI-DELS------ 319
T+ +E KP KD K L EP E+ PKP S L EL+
Sbjct: 1014 QAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDP 1073
Query: 320 EDFDR-SECKEKPS-----KPT-EKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLK 372
+F+ +ECK + PT TE + ++ + I+ PP P+ K
Sbjct: 1074 PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPK 1133
Query: 373 GT---VPDD------AVEALADSLGKKEAD--PEDGKPVMDKVKEKAK------------ 409
+ VP + AV + K+E + E K +++KVKE
Sbjct: 1134 ASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ 1193
Query: 410 -------EEDREKLGEKEETIPPDYRL----EEVKDKDGKPLLPKESKEQLPPMSEDFLL 458
E+D+ ++++ +P + +L E+++ ++ KPLL +E+ P + LL
Sbjct: 1194 KQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLL----EEKKPTPEDKKLL 1249
Query: 459 DALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD-----TSQSDKDL 513
Q LK +++ A ++ + T Q G P+ S + + L
Sbjct: 1250 PEAKTSAPEEQKHDLLK---SQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSL 1306
Query: 514 DDALDKLSDSLGQRQPDPDENKPMEDKVKE-KAKAEHRDKLGERDDTIPPEYRHLLDDNG 572
DK + ++ ++ P KP D+V+ K K E D + + P+ L D G
Sbjct: 1307 PKEDDKTTKTIKEQPQPPCTAKP--DQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTG 1364
Query: 573 QDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK-----KAAS 627
+ S P D++D + L D S S+ + + AK + +A +
Sbjct: 1365 YSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQA 1424
Query: 628 SSKAPKNGGKAKDSAKTTEETSKPKD 653
S+ A + K + + E +PKD
Sbjct: 1425 STLADEKSEKKTQPHEVSPE--QPKD 1448
Score = 50.8 bits (120), Expect = 4e-06
Identities = 120/603 (19%), Positives = 210/603 (34%), Gaps = 44/603 (7%)
Query: 3 PTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKP 62
P +T A +T P K + P + + ++ QQP ST+P +
Sbjct: 456 PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG--STKPPPQQ 513
Query: 63 QDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDT 122
+ S +PG K + +PA P + KP ++G L +
Sbjct: 514 PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS 573
Query: 123 LGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDDAIDALS 182
+ + P + ++ E + P+ + +
Sbjct: 574 PSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVK 633
Query: 183 S--DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAA----PPQEKKRKVEKDTMSDQA 236
C A G S+ K ++A ++A PQ ++ +KD Q
Sbjct: 634 EWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ- 692
Query: 237 LEALSASLGTRQAEPELDLRSIKEVDEAKAKE----EKLEKCGEDDE-TIPSEYRLKP-A 290
LS + ++ P + ++ AKAK+ + L K E ++PSE P A
Sbjct: 693 --DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVA 750
Query: 291 TDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVS 350
DK +P + +P S + ++ +S+ +EK + P + + + P
Sbjct: 751 DDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTG 810
Query: 351 EAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKE 410
E V A P PA+ + ++S G+K+ DP K K + K
Sbjct: 811 EKVSPFD----SKAIPRPASDSKIISHPGPS--SESKGQKQVDPVQKKEEPKKAQTKMSP 864
Query: 411 EDREKLGEKEETIPPDYRLEEVKDKDGKPLLPK-ESKEQLPPMSEDFLLDALSEDFSGPQ 469
+ K K PP R + PK + + + ++ + DA + PQ
Sbjct: 865 KPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQ 924
Query: 470 NASSLKF--EDAKLAAAISEVVSQT----PASTTQAGAPPRDT-SQSDKDLDDALDKLSD 522
+ K A + + S ++S P S + GAP + + S K
Sbjct: 925 ETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK--- 981
Query: 523 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 582
S GQ P P ++ P VK++ KA +KL + + P R + KP PP K
Sbjct: 982 STGQAPPAPAKSIP----VKKETKAPAAEKLEPKAEQAPTVKR----TETEKKP--PPIK 1031
Query: 583 KSE 585
S+
Sbjct: 1032 DSK 1034
Score = 46.6 bits (109), Expect = 7e-05
Identities = 139/723 (19%), Positives = 236/723 (32%), Gaps = 122/723 (16%)
Query: 2 NPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTK 61
+P + A K + K + KP L KQ + GS A K QP E + K
Sbjct: 683 SPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAK---------QPPEADSLSKPA 733
Query: 62 PQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES------KPDKPSGKSGMDAA 115
P S E A DK K+ K + P + S KPD PS K
Sbjct: 734 PPKEPSVPSEQDKAPVA-----DDKPKQPKMVKPTTDLVSSSSATTKPDIPSSK------ 782
Query: 116 LDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKP---- 171
+ + + T T P S P + + + + P ++++ P
Sbjct: 783 ----VQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSS 838
Query: 172 -------IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAG----TVRSAAPP 220
+ P + T SP K K T +AG T + + P
Sbjct: 839 ESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKP 898
Query: 221 QEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDET 280
QE+ R+ S +LG+ P+ + +E K +
Sbjct: 899 QEQSRR-------------FSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNL 945
Query: 281 IPSEYRLKPATDK-DGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTE 339
I + + P + G P+ P P S+ + P+K +
Sbjct: 946 ISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQ-------GPPKSTGQAPPAPAKSIPVKK 998
Query: 340 ESKAAAP---APVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPED 396
E+KA A P +E + PP K + L L +K PE
Sbjct: 999 ETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL-EKSPKPES 1057
Query: 397 GKPVMDKVKEKAKEEDREKLGEKEET---------IPPDYRLEEVKD------------- 434
P+ K + +D E P L E+++
Sbjct: 1058 TCPLC-KTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116
Query: 435 ---KDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQ 491
D + + P S + PM ++ S+ + P +K ++ ++ +V+ +
Sbjct: 1117 GQLGDIRKMPPAPSGPKASPMPVP--TESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILE 1174
Query: 492 TPASTTQAGAPPRDTSQSDKDLDDALDK-LSDSLGQRQPDPDENK--PMEDKVKEKAK-- 546
T P + K + L+K + +L +++P P+E K P E+K++ + K
Sbjct: 1175 KVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP 1234
Query: 547 --------AEHRDKLGERDDTIPPEYRH-LLDDNGQDKPVK----PPTKKSEDSKKPADD 593
E + L E + P E +H LL Q K K ++ K+P
Sbjct: 1235 LLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTK 1294
Query: 594 QDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAK----DSAKTTEETS 649
+ + SG S P + + T K++ + ++ GK K D T +
Sbjct: 1295 MEGLP--SGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQ 1352
Query: 650 KPK 652
+PK
Sbjct: 1353 QPK 1355
Score = 42.4 bits (98), Expect = 0.001
Identities = 131/653 (20%), Positives = 238/653 (36%), Gaps = 167/653 (25%)
Query: 3 PTETKAVKTEPEKKSQSTKP------------KSLPKQASDTGSNDAHN--KKAVSRSAE 48
P E K + E + +S+ KP K LP+ + H+ K V + E
Sbjct: 1215 PEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEE 1274
Query: 49 Q-------QPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 101
+ + ++ +P+TK + + S +S+ K DK + P P +
Sbjct: 1275 KLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLP-------KEDDKTTKTIKEQPQPPCTA 1327
Query: 102 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 161
KPD+ DD DT + + + TG SD +SS+ LG+ IP
Sbjct: 1328 KPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYS-SDGISSS----LGEIPSLIP 1382
Query: 162 PKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEEST--EVLKAQSAGTVRSAAP 219
+++L K + D + S + + SP+ K EST +L+AQ++
Sbjct: 1383 TDEKDIL-KGLKKD----SFSQESSPSSPSDLAKL----ESTVLSILEAQAS-------- 1425
Query: 220 PQEKKRKVEKDTMSDQALEALSASLGTRQAEP-ELDLRSIKEVDEAKAKEEKLEKCGEDD 278
T++D+ E ++ +P E+ K+ ++ ++ E LE ++
Sbjct: 1426 -----------TLADEKSE--------KKTQPHEVSPEQPKDQEKTQSLSETLEITISEE 1466
Query: 279 ETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKT 338
E S+ K KD + +P ++ + +SE +D+++ +P +
Sbjct: 1467 EIKESQEERKDTFKKDSQQDIPSSKDH---KEKSEFVDDITTR----------REPYDSV 1513
Query: 339 EESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGK 398
EES + +PV + RTS+ S S
Sbjct: 1514 EESSESENSPVPQRKRRTSVGSSSS----------------------------------- 1538
Query: 399 PVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLL 458
++ K+ED + GE+E+ I +E D+D ++F+
Sbjct: 1539 -------DEYKQEDSQGSGEEEDFIRKQI-IEMSADEDAS-----------GSEDDEFIR 1579
Query: 459 DALSEDFSGPQNASSLKFE-DAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDAL 517
+ L E S ++ + + K+ A +++ +++ A R S D+D D+A
Sbjct: 1580 NQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRH-SWHDED-DEAF 1637
Query: 518 DKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEY--------RHLLD 569
D+ S L R+ E+ E+ V R K E + TI +Y L
Sbjct: 1638 DE-SPELKYRETKSQES---EELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYF 1693
Query: 570 DNGQDKPVKPPTKKSEDSKK-------------PADDQDPIDALSGDLDSCPS 609
D + ++ T ED + P + +L D DS PS
Sbjct: 1694 DEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPS 1746
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 66.6 bits (161), Expect = 7e-11
Identities = 166/746 (22%), Positives = 266/746 (35%), Gaps = 126/746 (16%)
Query: 3 PTETKAVKTEPEKKSQSTKPKSLPKQASDT----GSNDAHNKKAVSRSAEQQPSEKSTEP 58
P + +V +E +K + PK T S+ A K + S Q +E+ T P
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
Query: 59 -----KTKPQDMISAGGESVAGIT--AISGKPGDKK--------KEKKSLTPAVPVESKP 103
KP GE V+ AI D K E K PV+ K
Sbjct: 794 PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE 853
Query: 104 DKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKR------E 157
+ ++ M D G P T G V P S +E +R
Sbjct: 854 EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA--GQTVPTPQQSPKPQEQSRRFSLNLGS 911
Query: 158 VTIPPKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSA 217
+T PK ++P P + + F G + S + A G +
Sbjct: 912 ITDAPK-----SQPTTPQETVTGKLFGF--------GASIFSQASNLISTAGQPGPHSQS 958
Query: 218 APPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE-EKLEKCGE 276
P K+ Q + T QA P +SI E KA EKLE E
Sbjct: 959 GPGAPMKQA----PAPSQPPTSQGPPKSTGQAPPA-PAKSIPVKKETKAPAAEKLEPKAE 1013
Query: 277 DDETIP-SEYRLKPATDKDGKPLLPEP---------EEKPKPRSESELI-DELS------ 319
T+ +E KP KD K L EP E+ PKP S L EL+
Sbjct: 1014 QAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDP 1073
Query: 320 EDFDR-SECKEKPS-----KPT-EKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLK 372
+F+ +ECK + PT TE + ++ + I+ PP P+ K
Sbjct: 1074 PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPK 1133
Query: 373 GT---VPDD------AVEALADSLGKKEAD--PEDGKPVMDKVKEKAK------------ 409
+ VP + AV + K+E + E K +++KVKE
Sbjct: 1134 ASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ 1193
Query: 410 -------EEDREKLGEKEETIPPDYRL----EEVKDKDGKPLLPKESKEQLPPMSEDFLL 458
E+D+ ++++ +P + +L E+++ ++ KPLL +E+ P + LL
Sbjct: 1194 KQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLL----EEKKPTPEDKKLL 1249
Query: 459 DALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD-----TSQSDKDL 513
Q LK +++ A ++ + T Q G P+ S + + L
Sbjct: 1250 PEAKTSAPEEQKHDLLK---SQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSL 1306
Query: 514 DDALDKLSDSLGQRQPDPDENKPMEDKVKE-KAKAEHRDKLGERDDTIPPEYRHLLDDNG 572
DK + ++ ++ P KP D+V+ K K E D + + P+ L D G
Sbjct: 1307 PKEDDKTTKTIKEQPQPPCTAKP--DQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTG 1364
Query: 573 QDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK-----KAAS 627
+ S P D++D + L D S S+ + + AK + +A +
Sbjct: 1365 YSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQA 1424
Query: 628 SSKAPKNGGKAKDSAKTTEETSKPKD 653
S+ A + K + + E +PKD
Sbjct: 1425 STLADEKSEKKTQPHEVSPE--QPKD 1448
Score = 50.8 bits (120), Expect = 4e-06
Identities = 120/603 (19%), Positives = 210/603 (34%), Gaps = 44/603 (7%)
Query: 3 PTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKP 62
P +T A +T P K + P + + ++ QQP ST+P +
Sbjct: 456 PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG--STKPPPQQ 513
Query: 63 QDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDT 122
+ S +PG K + +PA P + KP ++G L +
Sbjct: 514 PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS 573
Query: 123 LGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDDAIDALS 182
+ + P + ++ E + P+ + +
Sbjct: 574 PSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVK 633
Query: 183 S--DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAA----PPQEKKRKVEKDTMSDQA 236
C A G S+ K ++A ++A PQ ++ +KD Q
Sbjct: 634 EWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ- 692
Query: 237 LEALSASLGTRQAEPELDLRSIKEVDEAKAKE----EKLEKCGEDDE-TIPSEYRLKP-A 290
LS + ++ P + ++ AKAK+ + L K E ++PSE P A
Sbjct: 693 --DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVA 750
Query: 291 TDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVS 350
DK +P + +P S + ++ +S+ +EK + P + + + P
Sbjct: 751 DDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTG 810
Query: 351 EAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKE 410
E V A P PA+ + ++S G+K+ DP K K + K
Sbjct: 811 EKVSPFD----SKAIPRPASDSKIISHPGPS--SESKGQKQVDPVQKKEEPKKAQTKMSP 864
Query: 411 EDREKLGEKEETIPPDYRLEEVKDKDGKPLLPK-ESKEQLPPMSEDFLLDALSEDFSGPQ 469
+ K K PP R + PK + + + ++ + DA + PQ
Sbjct: 865 KPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQ 924
Query: 470 NASSLKF--EDAKLAAAISEVVSQT----PASTTQAGAPPRDT-SQSDKDLDDALDKLSD 522
+ K A + + S ++S P S + GAP + + S K
Sbjct: 925 ETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK--- 981
Query: 523 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 582
S GQ P P ++ P VK++ KA +KL + + P R + KP PP K
Sbjct: 982 STGQAPPAPAKSIP----VKKETKAPAAEKLEPKAEQAPTVKR----TETEKKP--PPIK 1031
Query: 583 KSE 585
S+
Sbjct: 1032 DSK 1034
Score = 46.6 bits (109), Expect = 7e-05
Identities = 139/723 (19%), Positives = 236/723 (32%), Gaps = 122/723 (16%)
Query: 2 NPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTK 61
+P + A K + K + KP L KQ + GS A K QP E + K
Sbjct: 683 SPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAK---------QPPEADSLSKPA 733
Query: 62 PQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES------KPDKPSGKSGMDAA 115
P S E A DK K+ K + P + S KPD PS K
Sbjct: 734 PPKEPSVPSEQDKAPVA-----DDKPKQPKMVKPTTDLVSSSSATTKPDIPSSK------ 782
Query: 116 LDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKP---- 171
+ + + T T P S P + + + + P ++++ P
Sbjct: 783 ----VQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSS 838
Query: 172 -------IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAG----TVRSAAPP 220
+ P + T SP K K T +AG T + + P
Sbjct: 839 ESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKP 898
Query: 221 QEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDET 280
QE+ R+ S +LG+ P+ + +E K +
Sbjct: 899 QEQSRR-------------FSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNL 945
Query: 281 IPSEYRLKPATDK-DGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTE 339
I + + P + G P+ P P S+ + P+K +
Sbjct: 946 ISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQ-------GPPKSTGQAPPAPAKSIPVKK 998
Query: 340 ESKAAAP---APVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPED 396
E+KA A P +E + PP K + L L +K PE
Sbjct: 999 ETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL-EKSPKPES 1057
Query: 397 GKPVMDKVKEKAKEEDREKLGEKEET---------IPPDYRLEEVKD------------- 434
P+ K + +D E P L E+++
Sbjct: 1058 TCPLC-KTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116
Query: 435 ---KDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQ 491
D + + P S + PM ++ S+ + P +K ++ ++ +V+ +
Sbjct: 1117 GQLGDIRKMPPAPSGPKASPMPVP--TESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILE 1174
Query: 492 TPASTTQAGAPPRDTSQSDKDLDDALDK-LSDSLGQRQPDPDENK--PMEDKVKEKAK-- 546
T P + K + L+K + +L +++P P+E K P E+K++ + K
Sbjct: 1175 KVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP 1234
Query: 547 --------AEHRDKLGERDDTIPPEYRH-LLDDNGQDKPVK----PPTKKSEDSKKPADD 593
E + L E + P E +H LL Q K K ++ K+P
Sbjct: 1235 LLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTK 1294
Query: 594 QDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAK----DSAKTTEETS 649
+ + SG S P + + T K++ + ++ GK K D T +
Sbjct: 1295 MEGLP--SGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQ 1352
Query: 650 KPK 652
+PK
Sbjct: 1353 QPK 1355
Score = 42.4 bits (98), Expect = 0.001
Identities = 131/653 (20%), Positives = 238/653 (36%), Gaps = 167/653 (25%)
Query: 3 PTETKAVKTEPEKKSQSTKP------------KSLPKQASDTGSNDAHN--KKAVSRSAE 48
P E K + E + +S+ KP K LP+ + H+ K V + E
Sbjct: 1215 PEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEE 1274
Query: 49 Q-------QPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 101
+ + ++ +P+TK + + S +S+ K DK + P P +
Sbjct: 1275 KLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLP-------KEDDKTTKTIKEQPQPPCTA 1327
Query: 102 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 161
KPD+ DD DT + + + TG SD +SS+ LG+ IP
Sbjct: 1328 KPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYS-SDGISSS----LGEIPSLIP 1382
Query: 162 PKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEEST--EVLKAQSAGTVRSAAP 219
+++L K + D + S + + SP+ K EST +L+AQ++
Sbjct: 1383 TDEKDIL-KGLKKD----SFSQESSPSSPSDLAKL----ESTVLSILEAQAS-------- 1425
Query: 220 PQEKKRKVEKDTMSDQALEALSASLGTRQAEP-ELDLRSIKEVDEAKAKEEKLEKCGEDD 278
T++D+ E ++ +P E+ K+ ++ ++ E LE ++
Sbjct: 1426 -----------TLADEKSE--------KKTQPHEVSPEQPKDQEKTQSLSETLEITISEE 1466
Query: 279 ETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKT 338
E S+ K KD + +P ++ + +SE +D+++ +P +
Sbjct: 1467 EIKESQEERKDTFKKDSQQDIPSSKDH---KEKSEFVDDITTR----------REPYDSV 1513
Query: 339 EESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGK 398
EES + +PV + RTS+ S S
Sbjct: 1514 EESSESENSPVPQRKRRTSVGSSSS----------------------------------- 1538
Query: 399 PVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLL 458
++ K+ED + GE+E+ I +E D+D ++F+
Sbjct: 1539 -------DEYKQEDSQGSGEEEDFIRKQI-IEMSADEDAS-----------GSEDDEFIR 1579
Query: 459 DALSEDFSGPQNASSLKFE-DAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDAL 517
+ L E S ++ + + K+ A +++ +++ A R S D+D D+A
Sbjct: 1580 NQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRH-SWHDED-DEAF 1637
Query: 518 DKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEY--------RHLLD 569
D+ S L R+ E+ E+ V R K E + TI +Y L
Sbjct: 1638 DE-SPELKYRETKSQES---EELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYF 1693
Query: 570 DNGQDKPVKPPTKKSEDSKK-------------PADDQDPIDALSGDLDSCPS 609
D + ++ T ED + P + +L D DS PS
Sbjct: 1694 DEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPS 1746
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 65.9 bits (159), Expect = 1e-10
Identities = 120/613 (19%), Positives = 224/613 (36%), Gaps = 90/613 (14%)
Query: 10 KTEPEKKSQSTKPKSLPKQASDTGSNDAHNK-KAVSRSAEQQPSEKSTEPKTKP---QDM 65
KTE ++K + + + + G K K ++ ++ EK +P+TK +
Sbjct: 147 KTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQK 206
Query: 66 ISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGG 125
+ E T K G ++K K++ V+ P KP K + A
Sbjct: 207 KAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAA--------- 257
Query: 126 PEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDDAIDALSSDF 185
E+ Y + + G+ PP E ++P A++ +
Sbjct: 258 -VSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGE- 315
Query: 186 TCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLG 245
KK EK+ ++E K + ++ K+K EK+T D + +
Sbjct: 316 --------KKKAEKKVTSETKKKEK----------EDIKKKSEKETAIDVEKKEPGKASE 357
Query: 246 TRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEK 305
T+Q ++ ++ + DE K +K +K P+E ++ K EP +
Sbjct: 358 TKQGTVKIAAQAAAKKDEKKEDSKKTKK--------PAEVEQPKGKKQEKKEKHVEPAKS 409
Query: 306 PKPRSESELIDELSEDFDRS-ECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSA 364
PK E S D+ + K + +K K A P E +T I+
Sbjct: 410 PK--------KEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKE 461
Query: 365 PPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIP 424
K ++ GK+E P K +K E K+E K G++ + P
Sbjct: 462 -------KSGKTSSILKDKEPIKGKEEKVPASLK---EKEPETKKDEKMSKAGKEVKPKP 511
Query: 425 PDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAA 484
P +L+ K++ +P + KE+K P +SE + +D P+ S + K
Sbjct: 512 P--QLQGKKEEKPEPQIKKEAK---PAISEKVQIH--KQDIVKPEKTVSHGKPEEK---- 560
Query: 485 ISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEK 544
V+ Q A T + A P+ T +++ ++ S+ +P P E K
Sbjct: 561 ---VLKQVKAVTIEKTAKPKPTKKAEH-----REREPPSIKTDKPKPTPKGTSEVTESGK 612
Query: 545 AKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDL 604
K E + E++ + +HL ++ + ++KPA +S D+
Sbjct: 613 KKTE----ISEKESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPA-------RVSKDV 661
Query: 605 DSCPSTTETSQNT 617
+ P++ + + T
Sbjct: 662 EDVPASKKAKEGT 674
Score = 43.9 bits (102), Expect = 5e-04
Identities = 65/307 (21%), Positives = 110/307 (35%), Gaps = 59/307 (19%)
Query: 370 TLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRL 429
T KG + + + K E + + + KV K KE+ +EK+ EKE+
Sbjct: 128 TDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHK 187
Query: 430 EEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVV 489
E+++ K+ KP +KEQ + + + ++ G K E K AA + V
Sbjct: 188 EKIEKKE-KPETKTLAKEQKKAKTAEKSEEKTKKEVKGG------KQEKVKQTAAKVKEV 240
Query: 490 SQTPASTTQAGAPPRDTSQSDKDLD---------------DALDKLSDSLGQRQPDPDEN 534
+TP+ + + + D D S ++ P +
Sbjct: 241 QKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQAS 300
Query: 535 KP------MEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK--SED 586
+P +E+K EK KAE K V TKK ED
Sbjct: 301 RPTPASPALEEKEGEKKKAE--------------------------KKVTSETKKKEKED 334
Query: 587 SKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTE 646
KK ++ + ID + +ET Q T K + AA + ++ K K A+ +
Sbjct: 335 IKKKSEKETAIDV---EKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQ 391
Query: 647 ETSKPKD 653
K ++
Sbjct: 392 PKGKKQE 398
Score = 43.1 bits (100), Expect = 8e-04
Identities = 62/286 (21%), Positives = 111/286 (38%), Gaps = 44/286 (15%)
Query: 7 KAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQP-SEKSTEPKTKPQDM 65
KAV + E+K+ T + + K+ S S+ +K+ + E+ P S K EP+TK +
Sbjct: 440 KAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEK 499
Query: 66 ISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGG 125
+S G+ V KP + + K P K KP+ + D++
Sbjct: 500 MSKAGKEV--------KPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVK---- 547
Query: 126 PEETEEENTTYTGPE--VSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDDAIDALSS 183
PE+T ++ PE V + + IE+ K + T ++RE I D
Sbjct: 548 PEKT----VSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKP------ 597
Query: 184 DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSAS 243
PT G E TE +G ++ +E K K + + ++ + S
Sbjct: 598 -----KPTPKG----TSEVTE------SGKKKTEISEKESKEKADMKHLREEKVSTRKES 642
Query: 244 LG----TRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEY 285
L T+ +P + +++V +K +E E + P +
Sbjct: 643 LQLHNVTKAEKPARVSKDVEDVPASKKAKEGTEDVSPTKQKSPISF 688
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 62.4 bits (150), Expect = 1e-09
Identities = 153/687 (22%), Positives = 230/687 (33%), Gaps = 96/687 (13%)
Query: 3 PTETKAVKTEPEKKSQSTKPK---SLPKQASDTGSND---AHNKKAVSRSAEQQPSEKST 56
PT TK+ T P++ + +T + + PK+ + T + + K A + E P+
Sbjct: 249 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 308
Query: 57 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 116
T P++ + T +P KE TP P + P KP+ + + A
Sbjct: 309 PAPTTPKEPAPTTPKEPTPTT--PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA- 365
Query: 117 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDD 176
T P T + + T P+ P ++ K K K P
Sbjct: 366 ---PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 422
Query: 177 AIDALSSDFTCGSPTAAGK---KTEKEESTEVLKAQSAGTVRSAAP--PQEKKRKVEKDT 231
+ + +PT K T KE + K + T + AP P+E K+T
Sbjct: 423 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 482
Query: 232 MSDQALEALSASLGTRQA--EPELDLRSIKEVDEAKAKEEKLEKCGEDD-ETIPSEYRLK 288
+ + L+ + + A PE + E EE E+ T P
Sbjct: 483 -APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK--AAA 539
Query: 289 PATDKDGKPLLP-EP----EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 343
P T K+ P P EP ++P P + E + + KE P+ T K K
Sbjct: 540 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE-PAPTTPKKPAPKE 598
Query: 344 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 403
AP E T C P P T KGT P E + KE P K
Sbjct: 599 LAPTTTKEPTSTT--CD----KPAPTTPKGTAPTTPKEPAPTT--PKEPAPTTPKGTAPT 650
Query: 404 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 463
++ +K KE + P KP P KE P ++
Sbjct: 651 TLKEPAPTTPKKPAPKE--LAPTTTKGPTSTTSDKP-APTTPKETAPTTPKE-------- 699
Query: 464 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQS---DKDLDDALDKL 520
P + K + +TP TT + P T + K D++ +L
Sbjct: 700 ----PAPTTPKK---------PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746
Query: 521 SDSLGQRQPDPDENKPMEDKV---------KEKAKAEHRDKLGERDDTIPPEYRHLLDDN 571
S + P EN P E V K + +DK ERD PE
Sbjct: 747 S---AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK- 802
Query: 572 GQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKA 631
K T+K+ +SK A + T+ T+Q+T K +++ A
Sbjct: 803 -MTKETATTTEKTTESKITA-------------TTTQVTSTTTQDTTPFKITTLKTTTLA 848
Query: 632 PKNGGKAKDSAKT-----TEETSKPKD 653
PK K T EET+KPKD
Sbjct: 849 PKVTTTKKTITTTEIMNKPEETAKPKD 875
Score = 50.4 bits (119), Expect = 5e-06
Identities = 101/497 (20%), Positives = 164/497 (32%), Gaps = 36/497 (7%)
Query: 170 KPIGPDDAIDALSS-DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVE 228
KP D+A L + DF +P + + K ++ + R + PP K
Sbjct: 81 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 140
Query: 229 KDTMSDQA-LEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 287
T++ + +E + +Q + KE + + + +EK D S+
Sbjct: 141 SLTVNKETTVETKETTTTNKQTSTDG-----KEKTTSAKETQSIEKTSAKDLAPTSKVLA 195
Query: 288 KPATDKDGK---PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAA 344
KP + P L P+E P P + E ++ + K P+ P E + +
Sbjct: 196 KPTPKAETTTKGPALTTPKE-PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 254
Query: 345 APAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKV 404
AP E T+ + P EPA P A + K+ A KP
Sbjct: 255 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 314
Query: 405 KEKAKEEDREKL-GEKEETIPPDYRLEEVKDKDGKPLLPKE-----SKEQLPPMSEDFLL 458
KE A +E +E P K+ P PK+ KE P ++
Sbjct: 315 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 374
Query: 459 DALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAP--PRDTS-QSDKDLDD 515
E + + E A + ++ PA TT AP P++ S + K+
Sbjct: 375 TTTKEP------SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428
Query: 516 ALDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQD 574
K ++P P K P KE A + + T P E
Sbjct: 429 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK----KPAPTTPKEPAPTTPKETAP 484
Query: 575 KPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKN 634
K T + + P + P +L P+T E T ++ + AP
Sbjct: 485 TTPKKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNT 542
Query: 635 GGKAKDSAKTTEETSKP 651
K+ A TT + P
Sbjct: 543 ---PKEPAPTTPKEPAP 556
Score = 42.4 bits (98), Expect = 0.001
Identities = 72/343 (20%), Positives = 114/343 (33%), Gaps = 45/343 (13%)
Query: 87 KKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPE-ETEEENTTYTGPEVSDPM 145
K KK+ T P P SG+D D + T P+ T + N T P+++
Sbjct: 67 KDNKKNRTKKKPTPKPPVVDEAGSGLDNG-DFKVTT---PDTSTTQHNKVSTSPKITT-- 120
Query: 146 SSTYIEELGKREVTIPPKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEV 205
AKPI P ++ S S T + T + + T
Sbjct: 121 -----------------------AKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTT 157
Query: 206 LKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAK 265
Q++ + ++ + +EK + D A + + T +AE ++ E
Sbjct: 158 TNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT 217
Query: 266 AKEEKLEKCGEDDETIPSEYRLKPATDKDGKPL------------LPEPEEKPKPRSESE 313
K E P+ + P T K+ P P ++P P + E
Sbjct: 218 PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 277
Query: 314 LIDELSEDFDRSECKEKPSKPTEKTEES-KAAAPAPVSEAVCRTSMCSIQSAPPEPA-TL 371
+++ + K P+ P E + K AP E T + P EPA T
Sbjct: 278 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 337
Query: 372 KGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDRE 414
K P E A + KK A +P KE A +E
Sbjct: 338 KEPAPTTPKEP-APTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 379
Score = 32.0 bits (71), Expect = 1.8
Identities = 54/255 (21%), Positives = 93/255 (36%), Gaps = 21/255 (8%)
Query: 406 EKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDF 465
E+ +E D + +K + PDY + KD K K+ PP+ + E
Sbjct: 38 ERGRECDCDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPKPPV--------VDEAG 89
Query: 466 SGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDT--SQSDKDLDDALDKLSDS 523
SG N K + VS +P TT PR + SD + +L ++
Sbjct: 90 SGLDN-GDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 148
Query: 524 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT--IPPEYRHLLDDNGQ-DKPVKPP 580
+ + NK KEK + + E+ + P + L + + K P
Sbjct: 149 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP 208
Query: 581 TKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKC----KKAASSSKAPKNGG 636
+ P ++P A + + P+T +++ T K+ K A ++ K P
Sbjct: 209 ALTTPKEPTPTTPKEP--ASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA-PT 265
Query: 637 KAKDSAKTTEETSKP 651
K+ A TT + P
Sbjct: 266 TTKEPAPTTPKEPAP 280
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 62.4 bits (150), Expect = 1e-09
Identities = 153/687 (22%), Positives = 230/687 (33%), Gaps = 96/687 (13%)
Query: 3 PTETKAVKTEPEKKSQSTKPK---SLPKQASDTGSND---AHNKKAVSRSAEQQPSEKST 56
PT TK+ T P++ + +T + + PK+ + T + + K A + E P+
Sbjct: 290 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 349
Query: 57 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 116
T P++ + T +P KE TP P + P KP+ + + A
Sbjct: 350 PAPTTPKEPAPTTPKEPTPTT--PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA- 406
Query: 117 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDD 176
T P T + + T P+ P ++ K K K P
Sbjct: 407 ---PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 463
Query: 177 AIDALSSDFTCGSPTAAGK---KTEKEESTEVLKAQSAGTVRSAAP--PQEKKRKVEKDT 231
+ + +PT K T KE + K + T + AP P+E K+T
Sbjct: 464 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 523
Query: 232 MSDQALEALSASLGTRQA--EPELDLRSIKEVDEAKAKEEKLEKCGEDD-ETIPSEYRLK 288
+ + L+ + + A PE + E EE E+ T P
Sbjct: 524 -APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK--AAA 580
Query: 289 PATDKDGKPLLP-EP----EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 343
P T K+ P P EP ++P P + E + + KE P+ T K K
Sbjct: 581 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE-PAPTTPKKPAPKE 639
Query: 344 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 403
AP E T C P P T KGT P E + KE P K
Sbjct: 640 LAPTTTKEPTSTT--CD----KPAPTTPKGTAPTTPKEPAPTT--PKEPAPTTPKGTAPT 691
Query: 404 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 463
++ +K KE + P KP P KE P ++
Sbjct: 692 TLKEPAPTTPKKPAPKE--LAPTTTKGPTSTTSDKP-APTTPKETAPTTPKE-------- 740
Query: 464 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQS---DKDLDDALDKL 520
P + K + +TP TT + P T + K D++ +L
Sbjct: 741 ----PAPTTPKK---------PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787
Query: 521 SDSLGQRQPDPDENKPMEDKV---------KEKAKAEHRDKLGERDDTIPPEYRHLLDDN 571
S + P EN P E V K + +DK ERD PE
Sbjct: 788 S---AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK- 843
Query: 572 GQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKA 631
K T+K+ +SK A + T+ T+Q+T K +++ A
Sbjct: 844 -MTKETATTTEKTTESKITA-------------TTTQVTSTTTQDTTPFKITTLKTTTLA 889
Query: 632 PKNGGKAKDSAKT-----TEETSKPKD 653
PK K T EET+KPKD
Sbjct: 890 PKVTTTKKTITTTEIMNKPEETAKPKD 916
Score = 50.4 bits (119), Expect = 5e-06
Identities = 101/497 (20%), Positives = 164/497 (32%), Gaps = 36/497 (7%)
Query: 170 KPIGPDDAIDALSS-DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVE 228
KP D+A L + DF +P + + K ++ + R + PP K
Sbjct: 122 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 181
Query: 229 KDTMSDQA-LEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 287
T++ + +E + +Q + KE + + + +EK D S+
Sbjct: 182 SLTVNKETTVETKETTTTNKQTSTDG-----KEKTTSAKETQSIEKTSAKDLAPTSKVLA 236
Query: 288 KPATDKDGK---PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAA 344
KP + P L P+E P P + E ++ + K P+ P E + +
Sbjct: 237 KPTPKAETTTKGPALTTPKE-PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 295
Query: 345 APAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKV 404
AP E T+ + P EPA P A + K+ A KP
Sbjct: 296 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 355
Query: 405 KEKAKEEDREKL-GEKEETIPPDYRLEEVKDKDGKPLLPKE-----SKEQLPPMSEDFLL 458
KE A +E +E P K+ P PK+ KE P ++
Sbjct: 356 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 415
Query: 459 DALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAP--PRDTS-QSDKDLDD 515
E + + E A + ++ PA TT AP P++ S + K+
Sbjct: 416 TTTKEP------SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469
Query: 516 ALDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQD 574
K ++P P K P KE A + + T P E
Sbjct: 470 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK----KPAPTTPKEPAPTTPKETAP 525
Query: 575 KPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKN 634
K T + + P + P +L P+T E T ++ + AP
Sbjct: 526 TTPKKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNT 583
Query: 635 GGKAKDSAKTTEETSKP 651
K+ A TT + P
Sbjct: 584 ---PKEPAPTTPKEPAP 597
Score = 42.4 bits (98), Expect = 0.001
Identities = 72/343 (20%), Positives = 114/343 (33%), Gaps = 45/343 (13%)
Query: 87 KKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPE-ETEEENTTYTGPEVSDPM 145
K KK+ T P P SG+D D + T P+ T + N T P+++
Sbjct: 108 KDNKKNRTKKKPTPKPPVVDEAGSGLDNG-DFKVTT---PDTSTTQHNKVSTSPKITT-- 161
Query: 146 SSTYIEELGKREVTIPPKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEV 205
AKPI P ++ S S T + T + + T
Sbjct: 162 -----------------------AKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTT 198
Query: 206 LKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAK 265
Q++ + ++ + +EK + D A + + T +AE ++ E
Sbjct: 199 TNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT 258
Query: 266 AKEEKLEKCGEDDETIPSEYRLKPATDKDGKPL------------LPEPEEKPKPRSESE 313
K E P+ + P T K+ P P ++P P + E
Sbjct: 259 PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 318
Query: 314 LIDELSEDFDRSECKEKPSKPTEKTEES-KAAAPAPVSEAVCRTSMCSIQSAPPEPA-TL 371
+++ + K P+ P E + K AP E T + P EPA T
Sbjct: 319 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 378
Query: 372 KGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDRE 414
K P E A + KK A +P KE A +E
Sbjct: 379 KEPAPTTPKEP-APTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 420
Score = 32.0 bits (71), Expect = 1.8
Identities = 54/255 (21%), Positives = 93/255 (36%), Gaps = 21/255 (8%)
Query: 406 EKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDF 465
E+ +E D + +K + PDY + KD K K+ PP+ + E
Sbjct: 79 ERGRECDCDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPKPPV--------VDEAG 130
Query: 466 SGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDT--SQSDKDLDDALDKLSDS 523
SG N K + VS +P TT PR + SD + +L ++
Sbjct: 131 SGLDN-GDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 189
Query: 524 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT--IPPEYRHLLDDNGQ-DKPVKPP 580
+ + NK KEK + + E+ + P + L + + K P
Sbjct: 190 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP 249
Query: 581 TKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKC----KKAASSSKAPKNGG 636
+ P ++P A + + P+T +++ T K+ K A ++ K P
Sbjct: 250 ALTTPKEPTPTTPKEP--ASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA-PT 306
Query: 637 KAKDSAKTTEETSKP 651
K+ A TT + P
Sbjct: 307 TTKEPAPTTPKEPAP 321
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 62.4 bits (150), Expect = 1e-09
Identities = 153/687 (22%), Positives = 230/687 (33%), Gaps = 96/687 (13%)
Query: 3 PTETKAVKTEPEKKSQSTKPK---SLPKQASDTGSND---AHNKKAVSRSAEQQPSEKST 56
PT TK+ T P++ + +T + + PK+ + T + + K A + E P+
Sbjct: 342 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 401
Query: 57 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 116
T P++ + T +P KE TP P + P KP+ + + A
Sbjct: 402 PAPTTPKEPAPTTPKEPTPTT--PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA- 458
Query: 117 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDD 176
T P T + + T P+ P ++ K K K P
Sbjct: 459 ---PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 515
Query: 177 AIDALSSDFTCGSPTAAGK---KTEKEESTEVLKAQSAGTVRSAAP--PQEKKRKVEKDT 231
+ + +PT K T KE + K + T + AP P+E K+T
Sbjct: 516 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 575
Query: 232 MSDQALEALSASLGTRQA--EPELDLRSIKEVDEAKAKEEKLEKCGEDD-ETIPSEYRLK 288
+ + L+ + + A PE + E EE E+ T P
Sbjct: 576 -APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK--AAA 632
Query: 289 PATDKDGKPLLP-EP----EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 343
P T K+ P P EP ++P P + E + + KE P+ T K K
Sbjct: 633 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE-PAPTTPKKPAPKE 691
Query: 344 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 403
AP E T C P P T KGT P E + KE P K
Sbjct: 692 LAPTTTKEPTSTT--CD----KPAPTTPKGTAPTTPKEPAPTT--PKEPAPTTPKGTAPT 743
Query: 404 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 463
++ +K KE + P KP P KE P ++
Sbjct: 744 TLKEPAPTTPKKPAPKE--LAPTTTKGPTSTTSDKP-APTTPKETAPTTPKE-------- 792
Query: 464 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQS---DKDLDDALDKL 520
P + K + +TP TT + P T + K D++ +L
Sbjct: 793 ----PAPTTPKK---------PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839
Query: 521 SDSLGQRQPDPDENKPMEDKV---------KEKAKAEHRDKLGERDDTIPPEYRHLLDDN 571
S + P EN P E V K + +DK ERD PE
Sbjct: 840 S---AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK- 895
Query: 572 GQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKA 631
K T+K+ +SK A + T+ T+Q+T K +++ A
Sbjct: 896 -MTKETATTTEKTTESKITA-------------TTTQVTSTTTQDTTPFKITTLKTTTLA 941
Query: 632 PKNGGKAKDSAKT-----TEETSKPKD 653
PK K T EET+KPKD
Sbjct: 942 PKVTTTKKTITTTEIMNKPEETAKPKD 968
Score = 59.3 bits (142), Expect = 1e-08
Identities = 120/616 (19%), Positives = 203/616 (32%), Gaps = 55/616 (8%)
Query: 55 STEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDA 114
++ P +K S +++ T S KP +KKK KK + E ++ S ++
Sbjct: 70 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKK----VIESEEITEEHSVSENQES 125
Query: 115 ALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGP 174
+ + +++ T ++ +S EL K+ K KP
Sbjct: 126 S-----------SSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPK 174
Query: 175 DDAIDALSS-----DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEK 229
+D S DF +P + + K ++ + R + PP K
Sbjct: 175 PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETS 234
Query: 230 DTMSDQA-LEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLK 288
T++ + +E + +Q + KE + + + +EK D S+ K
Sbjct: 235 LTVNKETTVETKETTTTNKQTSTDG-----KEKTTSAKETQSIEKTSAKDLAPTSKVLAK 289
Query: 289 PATDKDGK---PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAA 345
P + P L P+E P P + E ++ + K P+ P E + +A
Sbjct: 290 PTPKAETTTKGPALTTPKE-PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 348
Query: 346 PAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVK 405
P E T+ + P EPA P A + K+ A KP K
Sbjct: 349 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 408
Query: 406 EKAKEEDREKL-GEKEETIPPDYRLEEVKDKDGKPLLPKE-----SKEQLPPMSEDFLLD 459
E A +E +E P K+ P PK+ KE P ++
Sbjct: 409 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 468
Query: 460 ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAP--PRDTS-QSDKDLDDA 516
E + + E A + ++ PA TT AP P++ S + K+
Sbjct: 469 TTKEP------SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 522
Query: 517 LDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDK 575
K ++P P K P KE A + + T P E
Sbjct: 523 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK----KPAPTTPKEPAPTTPKETAPT 578
Query: 576 PVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNG 635
K T + + P + P +L P+T E T ++ + AP
Sbjct: 579 TPKKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNT- 635
Query: 636 GKAKDSAKTTEETSKP 651
K+ A TT + P
Sbjct: 636 --PKEPAPTTPKEPAP 649
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 62.4 bits (150), Expect = 1e-09
Identities = 153/687 (22%), Positives = 230/687 (33%), Gaps = 96/687 (13%)
Query: 3 PTETKAVKTEPEKKSQSTKPK---SLPKQASDTGSND---AHNKKAVSRSAEQQPSEKST 56
PT TK+ T P++ + +T + + PK+ + T + + K A + E P+
Sbjct: 383 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 442
Query: 57 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 116
T P++ + T +P KE TP P + P KP+ + + A
Sbjct: 443 PAPTTPKEPAPTTPKEPTPTT--PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA- 499
Query: 117 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDD 176
T P T + + T P+ P ++ K K K P
Sbjct: 500 ---PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 556
Query: 177 AIDALSSDFTCGSPTAAGK---KTEKEESTEVLKAQSAGTVRSAAP--PQEKKRKVEKDT 231
+ + +PT K T KE + K + T + AP P+E K+T
Sbjct: 557 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 616
Query: 232 MSDQALEALSASLGTRQA--EPELDLRSIKEVDEAKAKEEKLEKCGEDD-ETIPSEYRLK 288
+ + L+ + + A PE + E EE E+ T P
Sbjct: 617 -APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK--AAA 673
Query: 289 PATDKDGKPLLP-EP----EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 343
P T K+ P P EP ++P P + E + + KE P+ T K K
Sbjct: 674 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE-PAPTTPKKPAPKE 732
Query: 344 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 403
AP E T C P P T KGT P E + KE P K
Sbjct: 733 LAPTTTKEPTSTT--CD----KPAPTTPKGTAPTTPKEPAPTT--PKEPAPTTPKGTAPT 784
Query: 404 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 463
++ +K KE + P KP P KE P ++
Sbjct: 785 TLKEPAPTTPKKPAPKE--LAPTTTKGPTSTTSDKP-APTTPKETAPTTPKE-------- 833
Query: 464 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQS---DKDLDDALDKL 520
P + K + +TP TT + P T + K D++ +L
Sbjct: 834 ----PAPTTPKK---------PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 880
Query: 521 SDSLGQRQPDPDENKPMEDKV---------KEKAKAEHRDKLGERDDTIPPEYRHLLDDN 571
S + P EN P E V K + +DK ERD PE
Sbjct: 881 S---AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK- 936
Query: 572 GQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKA 631
K T+K+ +SK A + T+ T+Q+T K +++ A
Sbjct: 937 -MTKETATTTEKTTESKITA-------------TTTQVTSTTTQDTTPFKITTLKTTTLA 982
Query: 632 PKNGGKAKDSAKT-----TEETSKPKD 653
PK K T EET+KPKD
Sbjct: 983 PKVTTTKKTITTTEIMNKPEETAKPKD 1009
Score = 59.3 bits (142), Expect = 1e-08
Identities = 120/616 (19%), Positives = 203/616 (32%), Gaps = 55/616 (8%)
Query: 55 STEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDA 114
++ P +K S +++ T S KP +KKK KK + E ++ S ++
Sbjct: 111 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKK----VIESEEITEEHSVSENQES 166
Query: 115 ALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGP 174
+ + +++ T ++ +S EL K+ K KP
Sbjct: 167 S-----------SSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPK 215
Query: 175 DDAIDALSS-----DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEK 229
+D S DF +P + + K ++ + R + PP K
Sbjct: 216 PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETS 275
Query: 230 DTMSDQA-LEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLK 288
T++ + +E + +Q + KE + + + +EK D S+ K
Sbjct: 276 LTVNKETTVETKETTTTNKQTSTDG-----KEKTTSAKETQSIEKTSAKDLAPTSKVLAK 330
Query: 289 PATDKDGK---PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAA 345
P + P L P+E P P + E ++ + K P+ P E + +A
Sbjct: 331 PTPKAETTTKGPALTTPKE-PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 389
Query: 346 PAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVK 405
P E T+ + P EPA P A + K+ A KP K
Sbjct: 390 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 449
Query: 406 EKAKEEDREKL-GEKEETIPPDYRLEEVKDKDGKPLLPKE-----SKEQLPPMSEDFLLD 459
E A +E +E P K+ P PK+ KE P ++
Sbjct: 450 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 509
Query: 460 ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAP--PRDTS-QSDKDLDDA 516
E + + E A + ++ PA TT AP P++ S + K+
Sbjct: 510 TTKEP------SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 563
Query: 517 LDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDK 575
K ++P P K P KE A + + T P E
Sbjct: 564 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK----KPAPTTPKEPAPTTPKETAPT 619
Query: 576 PVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNG 635
K T + + P + P +L P+T E T ++ + AP
Sbjct: 620 TPKKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNT- 676
Query: 636 GKAKDSAKTTEETSKP 651
K+ A TT + P
Sbjct: 677 --PKEPAPTTPKEPAP 690
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 62.4 bits (150), Expect = 1e-09
Identities = 119/569 (20%), Positives = 205/569 (36%), Gaps = 93/569 (16%)
Query: 13 PEKKSQSTKP--KSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTK---PQDMIS 67
PE+K Q+ P K K+AS + S D+ ++ + P++K+ P + P +
Sbjct: 64 PERKLQANGPVAKKAKKKASSSDSEDSSEEE---EEVQGPPAKKAAVPAKRVGLPPGKAA 120
Query: 68 AGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPE 127
A + S ++ ++K+ + V ++K K K + D
Sbjct: 121 AKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDS-------DS 173
Query: 128 ETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDDAIDALSSDFTC 187
+E+E P+++ P++ K + PPK K A + SS +
Sbjct: 174 SSEDEPPKNQKPKIT-PVTV-------KAQTKAPPKPARAAPKIANGKAASSSSSSSSSS 225
Query: 188 GSPTAAGKKTEKEESTEVLKAQ--SAGTVRSAAPPQEKKRKVEKDTMSDQALEALS---- 241
S + +K V K Q + V++A P K E D+ SD+ E
Sbjct: 226 SSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSE-DSSSDEEEEQKKPMKN 284
Query: 242 -----ASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGE--DDETIPSEYRLKPATDKD 294
+S+ A P + +A K++ +E + D+ SE KP T
Sbjct: 285 KPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPT--- 341
Query: 295 GKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVC 354
K ++ + KP P ++ S D D SE E PSKP T+ S + PA +++
Sbjct: 342 -KAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNS-SNKPAVTTKS-- 397
Query: 355 RTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDRE 414
PA P V G+ ++ + + + E+
Sbjct: 398 -------------PAVKPAAAPKQPVGG--------------GQKLLTRKADSSSSEEES 430
Query: 415 KLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLD---ALSEDFSGPQNA 471
E+E+T + K K +Q P S D D + SE+ +
Sbjct: 431 SSSEEEKT---KKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSK 487
Query: 472 SSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDP 531
S++K + K+A PAS + A ++S SD ++ +KL R P
Sbjct: 488 SAVKKKPQKVAGG---AAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAP 544
Query: 532 DEN-------------KPMEDKVKEKAKA 547
N K E++ +EK KA
Sbjct: 545 KANGTSALTAQNGKAAKNSEEEEEEKKKA 573
Score = 55.8 bits (133), Expect = 1e-07
Identities = 84/379 (22%), Positives = 139/379 (36%), Gaps = 67/379 (17%)
Query: 324 RSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEAL 383
+++ K S + +EE + P +A + PP A K + + E+
Sbjct: 77 KAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGL---PPGKAAAKASESSSSEESS 133
Query: 384 ADSLGKKEADPEDGK--PVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 441
D D ED K PV VK +AK K D E+ K+ KP +
Sbjct: 134 DDD------DEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKI 187
Query: 442 -----------PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVS 490
P + P ++ A S S ++SS E+ K AA + V
Sbjct: 188 TPVTVKAQTKAPPKPARAAPKIANG---KAASSSSSSSSSSSSDDSEEEKAAATPKKTVP 244
Query: 491 Q----TPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQ-----------PDPDEN- 534
+ A A P R +S S+ D ++ + + P P ++
Sbjct: 245 KKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSL 304
Query: 535 --KPMEDKVKEKAKAEHRDKLGERDDTIPPEYRH----LLDDNGQDKPVKPPTKKSEDSK 588
+P + V+++ E + + D+ E + + KP PP KK+ +S
Sbjct: 305 GTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKP--PPAKKAAESS 362
Query: 589 KPADDQDPIDALSGDLDSCPS----TTETSQN----TAKDKCKKAASSSKAPKNGG---- 636
+ D D S + D PS TT+ S N T K K A++ K P GG
Sbjct: 363 SDSSDSD-----SSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLL 417
Query: 637 -KAKDSAKTTEETSKPKDD 654
+ DS+ + EE+S +++
Sbjct: 418 TRKADSSSSEEESSSSEEE 436
Score = 50.4 bits (119), Expect = 5e-06
Identities = 68/352 (19%), Positives = 130/352 (36%), Gaps = 49/352 (13%)
Query: 3 PTETKAVKTEPEKKS-QSTKPKSLPKQASDTGSNDAHNKK------AVSRSAEQQP-SEK 54
P K++ T+P KK+ + +P + +SD + + +K VS++ + P ++K
Sbjct: 298 PPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKK 357
Query: 55 STEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDA 114
+ E + D S+ + A + K K + +PAV + P +P G
Sbjct: 358 AAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGG---- 413
Query: 115 ALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGP 174
L+ +EEE+++ + +++T + K +++P K P G
Sbjct: 414 --QKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQA-----PQGS 466
Query: 175 DDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD 234
D+ SSD S +KT K + + + AG + P KK K E S
Sbjct: 467 RDS----SSDSDSSSSEEEEEKTSKS-AVKKKPQKVAGGAAPSKPASAKKGKAESSNSSS 521
Query: 235 QALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKD 294
D ++ +EEKL+ G P T ++
Sbjct: 522 SD-------------------------DSSEEEEEKLKGKGSPRPQAPKANGTSALTAQN 556
Query: 295 GKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 346
GK EE+ + + + ++ + R + + T + ++ K P
Sbjct: 557 GKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTP 608
>gi|109637791 transcription factor-like nuclear regulator [Homo
sapiens]
Length = 2624
Score = 62.4 bits (150), Expect = 1e-09
Identities = 93/400 (23%), Positives = 165/400 (41%), Gaps = 55/400 (13%)
Query: 154 GKREVTIPPKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGT 213
G+RE++ E+L K + + AL T T+ + E +T+ +++ T
Sbjct: 823 GRREIS---SKEEVLEKILVSGEMAAALRE--TVRLDTSPKEMVPAEINTKEMQSDLKET 877
Query: 214 VRSAAPPQEKKRKVEKDTMS-DQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLE 272
R A P+EK V DT+ + L+A+ + R+ PE+ +D + ++ LE
Sbjct: 878 GRRAISPREKILDVIDDTIEMETGLKAMGREICLREKTPEV-------IDATEEIDKDLE 930
Query: 273 KCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPS 332
+ G R + + K+G PEE KP E E +L + S +EK
Sbjct: 931 EAG----------RREISPQKNG------PEEV-KPLGEVET--DLKATGNESSPREKTP 971
Query: 333 KPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEA 392
+ T+ TEE + + + T I P +K P D +E ++ G++ +
Sbjct: 972 EVTDATEE--------IDKNLEETGRRKISPRENGPEEVK---PVDEMETDLNATGRESS 1020
Query: 393 DPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDK-DGKPLLPKESKEQLPP 451
E V+D +E EE + E P + LEEVK + + L ++ P
Sbjct: 1021 PREKTPEVIDATEEIDLEET------EREVSPQENGLEEVKPLGEMETDLKATGRDSFPR 1074
Query: 452 MSEDFLLDALSE---DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 508
++DA+ E D + S + + + E+ QT T PR+ +
Sbjct: 1075 GKTPEVIDAIEEIEIDLEETEREISPQENGLEEVKPLGEM--QTDLKATGREISPREKTP 1132
Query: 509 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAE 548
D + +DK + G+R+ P+EN P E K ++ + +
Sbjct: 1133 EVIDATEEIDKDLEETGRREISPEENGPEEVKPVDEMETD 1172
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 60.5 bits (145), Expect = 5e-09
Identities = 102/520 (19%), Positives = 184/520 (35%), Gaps = 77/520 (14%)
Query: 173 GPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTM 232
G D++ D SS GS +++G +E E S+ +A S P K + D
Sbjct: 420 GADNSRDDSSSH--SGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNW 477
Query: 233 SDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATD 292
++ + + P + S + KE + + G TD
Sbjct: 478 LNK--------VNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNS------------YTD 517
Query: 293 KDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEA 352
G P+ P +S+ I + SE + S T + P +A
Sbjct: 518 TSG----PKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKA 573
Query: 353 VCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGK---KEADPEDGKPVMDKVKEKAK 409
++ P L ++P +A K K+ +P +K K K+
Sbjct: 574 AAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKST 633
Query: 410 EEDREKLGE------------KEETIPPDYRLEEVKDKDGKPLLPKESKEQ--------L 449
+ +K E + E++PP + + + + P+ P +E+
Sbjct: 634 SKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMF 693
Query: 450 PPMSEDFLLDALSEDFSGPQNASSL--KFEDAKLAAAISEVVSQT-PASTTQAGAPPRDT 506
PM E LL LSE P + L K + L + +T P + P + T
Sbjct: 694 SPMEEKELLSPLSE----PDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHT 749
Query: 507 SQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT------- 559
++ K A +K+S+ ++ + D+N+ E K K K E ++ G + +
Sbjct: 750 REAQKQ---ASEKVSNKGKRKHKNEDDNRASESK---KPKTEDKNSAGHKPSSNRESSKQ 803
Query: 560 IPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAK 619
+ + LL P K P + K+ + + S +++ S +T+K
Sbjct: 804 SAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSK 863
Query: 620 DKCKKAASSS-------KAPKNGGKAKDSAKTTEETSKPK 652
K + +SS KAP + SA T ++SKP+
Sbjct: 864 QKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTL-DSSKPR 902
Score = 53.5 bits (127), Expect = 6e-07
Identities = 114/567 (20%), Positives = 202/567 (35%), Gaps = 91/567 (16%)
Query: 3 PTETKAVKTEPEKKSQSTKPKSLPKQASDTGS-----NDAHNKKAVSRSAEQQPSEKSTE 57
P T +EP + S +S +GS +D+ ++ + S S +PS+ S
Sbjct: 403 PRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQ-SAS 461
Query: 58 PKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALD 117
P+ +P P +K + L + P K S S +D+
Sbjct: 462 PEPEP-------------------PPTNKWQLDNWLN-----KVNPHKVSPASSVDS--- 494
Query: 118 DLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDDA 177
++ + G +E E+ T ++Y + G +E + A P G D
Sbjct: 495 NIPSSQGYKKEGREQGT-----------GNSYTDTSGPKETS--------SATP-GRDSK 534
Query: 178 IDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQAL 237
S+ G + + + V K Q ++AA K+E +T D A
Sbjct: 535 TIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLAS 594
Query: 238 EALS-----ASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDD-ETIPSEYRLKPAT 291
S A+ G+R+ + + +S K K + K + E I ++ ++
Sbjct: 595 SMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETD---TSSS 651
Query: 292 DKDGKPLLPEPEEKPK-PRSESELIDELSEDFDRSECKEKPSKPTEKTE-ESKAAAPAPV 349
D D LP + PK P S + S + + S +++ P E+ E S + P
Sbjct: 652 DSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDR 711
Query: 350 SEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAK 409
+ + + + P +P K T P + +EA + + V +K K K K
Sbjct: 712 YPLIVKIDLNLLTRIPGKP--YKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHK 769
Query: 410 EEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQ 469
ED + E ++ + E+ KP +ES +Q +D L +GP
Sbjct: 770 NEDDNRASESKKP-----KTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSP-----AGPV 819
Query: 470 NASSLKFEDAKLAAAISEV---------------VSQTPASTTQAGAPPRDTSQSDKDLD 514
+ K E IS+ S+ +ST++ TS S K++
Sbjct: 820 PSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVK 879
Query: 515 DALDKLSDSLGQRQPDPDENKPMEDKV 541
+ S + P D +KP K+
Sbjct: 880 EKAPSSSSNCPPSAPTLDSSKPRRTKL 906
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 57.8 bits (138), Expect = 3e-08
Identities = 119/567 (20%), Positives = 204/567 (35%), Gaps = 103/567 (18%)
Query: 12 EPEKKSQSTKPKSLPKQASDTGSNDAHN-----KKAVSRSAEQQPS------EKSTEPKT 60
E E K +K + PK +GS+D + KKA ++ + ++ K
Sbjct: 115 ELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKI 174
Query: 61 KPQDMISAGGESV-AGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL--- 116
K + I++ GES + + G KK +K P + ++ D S K A
Sbjct: 175 KERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAE 234
Query: 117 ---------DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP----PK 163
D+ L +E EE T + EE K +VT+ P
Sbjct: 235 KKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPA 294
Query: 164 YRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 223
E P +D + G KK +K E E K EK
Sbjct: 295 SEEKAETPTAAEDDNE--------GDKKKKDKKKKKGEKEEKEK--------------EK 332
Query: 224 KRKVEKDTMS--DQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETI 281
K+ K T+ +AL L ++ E E ++ ++E++ + +EE+LE+ + +
Sbjct: 333 KKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQ-EKRERKK 391
Query: 282 PSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES 341
E K K+GK LL + + + + R+E+ L ++ + P K ++
Sbjct: 392 QKEKERKERLKKEGK-LLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKK 450
Query: 342 KAAAPAPVSEAVCRTSM--CSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKP 399
+ P + SM C+ AVE + + +KE P +P
Sbjct: 451 RKKIPQQLESKEVSESMELCA------------------AVEVMEQGVPEKEETPPPVEP 492
Query: 400 VMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLD 459
++ E A +D E + EET + ++ K+ P+E +E+ ED +
Sbjct: 493 EEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKEN----PEEEEEEEEEEEEDEESE 548
Query: 460 ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDK 519
E+ G S ED K++ D S K LD K
Sbjct: 549 E-EEEEEGESEGSEGDEEDEKVS----------------------DEKDSGKTLDKKPSK 585
Query: 520 LSDSLGQRQPDPDENKPMEDKVKEKAK 546
S + D D+++ E++ +KAK
Sbjct: 586 EMSS--DSEYDSDDDRTKEERAYDKAK 610
Score = 56.2 bits (134), Expect = 9e-08
Identities = 125/645 (19%), Positives = 233/645 (36%), Gaps = 117/645 (18%)
Query: 16 KSQSTKPKSLPKQASDTGSNDAHNKKA-VSRSAEQQPSEKSTEPKTKPQDM--------- 65
K Q K + K D + A + A ++ E Q S+ + + K QD
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKEL 62
Query: 66 --ISAGGESV-AGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDT 122
+S + + A ++ KP + +E+ + SK K G+ G + DD
Sbjct: 63 EELSLEAQGIKADRETVAVKPTENNEEEFT--------SKDKKKKGQKGKKQSFDD---- 110
Query: 123 LGGPEETEEENTTY---TGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDDAID 179
EE E++++ P+V S ++ K K ++ K G ++ D
Sbjct: 111 -NDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDED 169
Query: 180 ALSSDFTCGSPTAAGKK-TEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALE 238
++G+ E +E + K Q P E + + + + +
Sbjct: 170 NSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVA 229
Query: 239 ALSASLGTRQA----EPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKD 294
A R+ E + LR +KE +E + ++ K E E T
Sbjct: 230 QKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDT 289
Query: 295 GKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVC 354
G ++P EEK + + +E D+ D + + K+K + EK +E K
Sbjct: 290 G--VIPASEEKAETPTAAE--DDNEGDKKKKDKKKKKGEKEEKEKEKKKG---------- 335
Query: 355 RTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDRE 414
P AT+K +A+ L + +++ + E+ +++++ K KEE+R
Sbjct: 336 -----------PSKATVKAM--QEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERL 382
Query: 415 KLGEKEETIPPDYRLEEVKDKDGKPLLPKE----------------------SKEQLP-- 450
+ ++E + +E K+GK L + SK+ LP
Sbjct: 383 EQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKK 442
Query: 451 -PMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPAS--TTQAGAPPRDTS 507
P+ ED + + + + S++ L AA+ + P T P +
Sbjct: 443 RPIYEDKKRKKIPQQLESKEVSESME-----LCAAVEVMEQGVPEKEETPPPVEPEEEED 497
Query: 508 QSDKDLDDALDKLSDSLGQR---------------QPDPDENKPMEDKVKEKAKAEHRDK 552
D LDD SD ++ + + +E + ED+ E+ + E +
Sbjct: 498 TEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGES 557
Query: 553 LG----ERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADD 593
G E D+ + E D+G+ KP + S DS+ +DD
Sbjct: 558 EGSEGDEEDEKVSDE-----KDSGKTLDKKPSKEMSSDSEYDSDD 597
Score = 43.9 bits (102), Expect = 5e-04
Identities = 87/397 (21%), Positives = 139/397 (35%), Gaps = 63/397 (15%)
Query: 5 ETKAVKTEPEKKSQSTKPKSL----PKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
+ KA K E E+K + + L K+ +TG D +K R E++ + T
Sbjct: 230 QKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDT 289
Query: 61 KPQDMISAGGESVAGITAISG-KPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDA-ALDD 118
+I A E TA GDKKK+ K E + +K G S A+ +
Sbjct: 290 ---GVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQE 346
Query: 119 LIDTLGGPEET--------------------EEENTTYTGPEVSDPMSSTYIEELGKREV 158
+ L EE EEE E E L K
Sbjct: 347 ALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGK 406
Query: 159 TIPPKYRELLAKPIGPDDAIDALSSDFTCGS------PTAAGKKTEK----------EES 202
+ RE A+ + A + P KK +K ES
Sbjct: 407 LLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSES 466
Query: 203 TEVLKA-----QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAE------- 250
E+ A Q PP E + + + + EA+++ T + E
Sbjct: 467 MELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIE 526
Query: 251 ----PELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKD-GKPLLPEPEEK 305
PE + +E +E + EE+ E+ GE + + E K + +KD GK L +P ++
Sbjct: 527 VKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKE 586
Query: 306 PKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESK 342
SE + D+ +++ +R+ K K + E SK
Sbjct: 587 MSSDSEYDSDDDRTKE-ERAYDKAKRRIEKRRLEHSK 622
Score = 39.3 bits (90), Expect = 0.012
Identities = 57/289 (19%), Positives = 115/289 (39%), Gaps = 24/289 (8%)
Query: 377 DDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEE----DREKLGEK-EETIPPDYRLEE 431
DD ++ L + + + D + V K E +EE D++K G+K ++ D EE
Sbjct: 56 DDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEE 115
Query: 432 VKDKDGKPLLPKESK-EQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVS 490
++DKD K + K E +D + L + G S+ K++ ++ S+ +
Sbjct: 116 LEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIK 175
Query: 491 QTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQP-----DPDENKPMEDKVKEKA 545
+ ++ + +SD+ L + + + P + D++ + K +
Sbjct: 176 E----RSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQK 231
Query: 546 KAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPAD---------DQDP 596
KAE +++ ++ D + R L + + K +K+ E +K + D
Sbjct: 232 KAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGV 291
Query: 597 IDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTT 645
I A ++ + + ++ K K KK K K K K +K T
Sbjct: 292 IPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKAT 340
Score = 37.0 bits (84), Expect = 0.057
Identities = 40/168 (23%), Positives = 77/168 (45%), Gaps = 26/168 (15%)
Query: 505 DTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEY 564
D+++ D DLD ++ + ++ +P ++K + K K+K + D L E ++ + E
Sbjct: 11 DSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEE-LSLEA 69
Query: 565 RHL-----------LDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTET 613
+ + ++N ++ K KK + KK + D + + L D DS
Sbjct: 70 QGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELE-DKDS------K 122
Query: 614 SQNTAKDKCKKAASS------SKAPKNG-GKAKDSAKTTEETSKPKDD 654
S+ TAK K + + S +K PK GKA+ S K + + + +D+
Sbjct: 123 SKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDN 170
Score = 32.3 bits (72), Expect = 1.4
Identities = 65/295 (22%), Positives = 110/295 (37%), Gaps = 38/295 (12%)
Query: 372 KGTVPDDAVEALADSLGK-KEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLE 430
K + DA+ A + G KE +P+ K K K+K ++ + L E EE +
Sbjct: 14 KDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEEL---SLEAQ 70
Query: 431 EVK-DKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVV 489
+K D++ + P E+ E E+F + Q F+D SE +
Sbjct: 71 GIKADRETVAVKPTENNE------EEF---TSKDKKKKGQKGKKQSFDDND-----SEEL 116
Query: 490 SQTPASTTQAGAPPRDTSQSDKDLDDALDKL-------SDSLGQRQPDPDENKPMEDKVK 542
+ S ++ A P+ S D DD +KL + ++ +E++ K+K
Sbjct: 117 -EDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIK 175
Query: 543 EKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVK-PPTKKSEDSKKPADDQDPIDALS 601
E+++ + G+ D L GQ K K P E + D I ++
Sbjct: 176 ERSRINSSGESGDESD------EFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVA 229
Query: 602 GDLDSCPSTTETSQNTAKDKCKKAASSSK---APKNGGKAKDS-AKTTEETSKPK 652
++ K K +K + K+ K K+S K EET K K
Sbjct: 230 QKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSK 284
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 56.6 bits (135), Expect = 7e-08
Identities = 107/476 (22%), Positives = 180/476 (37%), Gaps = 55/476 (11%)
Query: 216 SAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG 275
S+APP + E A + + S T ++ D S +++ E
Sbjct: 447 SSAPPSAPQSLPEPVA---SAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAP 503
Query: 276 EDDETIPSEYRLKPATDKDGKPLLPEPE-----EKPKPRSESELIDELSEDFDRSECKEK 330
E + ++++L K +P P PE E P+ ES+ + + + SE K+
Sbjct: 504 EPEPPTTNKWQLDNWLTKVSQPAAP-PEGPRSTEPPRRHPESKGSSDSATSQEHSESKDP 562
Query: 331 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADS---- 386
P K + K + AP P + C+ S Q PP+ T+ P V+A A +
Sbjct: 563 PPKSSSKAPRAPPEAPHP-GKRSCQKS--PAQQEPPQRQTVGTKQPKKPVKASARAGSRT 619
Query: 387 --LGKKEAD--PEDGKPVMDKVKEKAKEEDREKL---GEKEETIPPDYRLEEVKDKDGKP 439
G++E P + K K K K + R + E + +PP E+ K K P
Sbjct: 620 SLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPS--SEKKKHKSSLP 677
Query: 440 LL------PKESKEQLPPMS-EDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQ- 491
P+ +K+ + + E F L L+E P + S + + A + E +
Sbjct: 678 APSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKD 737
Query: 492 ---TPASTTQAGAPPRDT----SQSDKDLDDALDKLSD--SLGQRQPDPDENKPMEDK-- 540
P T+ +P RDT S K D L ++ G RQ ++ +P K
Sbjct: 738 RLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKH 797
Query: 541 VKEKAKAEHRDKLGERDDTIPPEYRHLLDDN--GQDKPVKPPTKKSEDSKKPADDQDP-- 596
EK ++ KL ++ E D+ +K +K + S S K + P
Sbjct: 798 SSEKRSSDSSSKLAKKR---KGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSR 854
Query: 597 --IDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSK 650
+ ++ P + +SQ AK K+ S +A G SA +T+ K
Sbjct: 855 PSSQSSKKEMLPPPPVSSSSQKPAKPALKR--SRREADTCGQDPPKSASSTKSNHK 908
Score = 41.2 bits (95), Expect = 0.003
Identities = 118/588 (20%), Positives = 196/588 (33%), Gaps = 92/588 (15%)
Query: 13 PEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGES 72
P + + P+SLP+ + AH+ A S S S +E ++ D S E
Sbjct: 445 PSSSAPPSAPQSLPEPVA-----SAHSSSAESESTSDSDSSSDSESESSSSD--SEENEP 497
Query: 73 VAGITAISGKPGDKKKE-----KKSLTPAVPVE----SKPDK--PSGKSGMDAALDDLID 121
+ P K + K PA P E ++P + P K D+A
Sbjct: 498 LETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHS 557
Query: 122 TLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRE-LLAKPIGPDDAIDA 180
P PE P GKR P +E + +G
Sbjct: 558 ESKDPPPKSSSKAPRAPPEAPHP---------GKRSCQKSPAQQEPPQRQTVGTKQPKKP 608
Query: 181 LSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEAL 240
+ + GS T+ + E+E L + S P+ K + + S++ A+
Sbjct: 609 VKASARAGSRTSL--QGEREPG---LLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAV 663
Query: 241 SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP 300
S ++ + L S K + + ++ +E + P + L P T+ G P
Sbjct: 664 PPSSEKKKHKSSLPAPS-KALSGPEPAKDNVE------DRTPEHFALVPLTESQGPP--- 713
Query: 301 EPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCS 360
S C++ + + K P P+ + T + S
Sbjct: 714 ----------------HSGSGSRTSGCRQ---AVVVQEDSRKDRLPLPLRD----TKLLS 750
Query: 361 IQSAPPEPATLKGTVPDDAVEALADSLGK--KEADPEDGKPVMDK--VKEKAKEEDREKL 416
P P +L + D + + GK ++ ED +P K EK + KL
Sbjct: 751 PLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKL 810
Query: 417 GEKEETIPPDYRLEEVKDKDGKPL-LPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLK 475
+K + E +D D K + L KE K Q S + ++ S P + SS K
Sbjct: 811 AKKRKG-------EAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKP-SRPSSQSSKK 862
Query: 476 FEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD-ALDKLSDSLGQRQPDPDEN 534
E++ P S++ +S ++ D D + + D +
Sbjct: 863 -----------EMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSS 911
Query: 535 KPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 582
P + +V+ K + G DT P L NG KP KP K
Sbjct: 912 IPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSL-PNGNSKPGKPQVK 958
Score = 35.0 bits (79), Expect = 0.22
Identities = 46/202 (22%), Positives = 69/202 (34%), Gaps = 41/202 (20%)
Query: 469 QNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPP----------------RDTSQSDKD 512
Q SS+ +D +L+ + QTP + APP S+S D
Sbjct: 417 QGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSD 476
Query: 513 LDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNG 572
D + D S+S D +EN+P+E E PP DN
Sbjct: 477 SDSSSDSESES---SSSDSEENEPLETPAPEPE---------------PPTTNKWQLDNW 518
Query: 573 QDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAP 632
K +P + P S D + TSQ ++ K SSSKAP
Sbjct: 519 LTKVSQPAAPPEGPRSTEPPRRHPESKGSSD-------SATSQEHSESKDPPPKSSSKAP 571
Query: 633 KNGGKAKDSAKTTEETSKPKDD 654
+ +A K + + S + +
Sbjct: 572 RAPPEAPHPGKRSCQKSPAQQE 593
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 55.1 bits (131), Expect = 2e-07
Identities = 114/561 (20%), Positives = 211/561 (37%), Gaps = 114/561 (20%)
Query: 172 IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDT 231
I P+ L DF ++ ++ E E S + S+ + EK RK E+ +
Sbjct: 174 IHPEGVASLLPPDFQ-----SSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRS 228
Query: 232 MSDQALEALSASLGTRQAEPELDL------------RSIK----EVDEAKAKEEKLEKCG 275
+ A S G++ AE E D R++K E +E + +E+ E+ G
Sbjct: 229 SRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEG 288
Query: 276 EDDETIPSEYRLKPATDKDGKPL---LPEP--EEKPKPRSESELIDELSEDFDRS----- 325
+D+ E + ++G+ + PE +E+PK RS+ + + E F RS
Sbjct: 289 DDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEAR 348
Query: 326 ------ECKEKPSKPTEKTEE--------------SKAAAPAPVSEAVCRTSMCSI---- 361
+ +EK K T EE SK+ +P ++E + S+ ++
Sbjct: 349 KSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQT 408
Query: 362 ---QSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDG--KPVMDKVKEKAKEEDREKL 416
+ PP T + + P + ++ +E +P +G PV+ ++ + D +L
Sbjct: 409 ASEEETPPPLLTKEASSPPPHPQLHSE----EEIEPMEGPAPPVLIQLSPPNTDADTREL 464
Query: 417 GEKEETI-----------PPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDF 465
+ T+ P D + E +K +P+ES LP + + L D ++
Sbjct: 465 LVSQHTVQLVGGLSPLSSPSDTKAESPAEK-----VPEES--VLPLVQKSTLADYSAQKD 517
Query: 466 SGPQNASS-----LKFEDAKLAAAISEVVSQTPASTTQAGAPPRDT--------SQSDKD 512
P++ S LK E+ LA I+E + P+ + G T +D
Sbjct: 518 LEPESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSS 577
Query: 513 LDDALDKLSDSLGQRQPDPD-----ENKPMEDKVKEKAKA------EHRDKLGER---DD 558
+ S S R PD + P+ K ++ A+A R K+G R +
Sbjct: 578 SSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSES 637
Query: 559 TIPPEYRHLLDDNGQDKPVKPPTKKSE-----DSKKPADDQDPIDALSGDLDSCPSTTET 613
R + K + P + ++K P+ Q+ L C T
Sbjct: 638 RSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVATPPVPQLQVCEPKERT 697
Query: 614 SQNTAKDKCKKAASSSKAPKN 634
S +++ + ++ + A K+
Sbjct: 698 STSSSSVQARRLSQPESAEKH 718
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 54.7 bits (130), Expect = 3e-07
Identities = 136/665 (20%), Positives = 246/665 (36%), Gaps = 113/665 (16%)
Query: 10 KTEPEKKSQSTKP-KSLPKQASDTGSNDAHNKKAVS-RSAEQQPSEKSTEPKTKPQDMIS 67
KT + K+Q+ K K K+ S T +D KK S +S+ ++ T+ ++ D
Sbjct: 724 KTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYD--- 780
Query: 68 AGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTL--GG 125
E I ++S K G + KK + +S D+ K GMD + T G
Sbjct: 781 --SELEKEIKSMS-KIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGS 837
Query: 126 PEETE--EENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDDAIDALSS 183
++ E +E T++ E + +T +E + PK ++ A D +D LS
Sbjct: 838 SDDAERKQERETFSSAEGTVDKDTTIMELRDRL-----PKKQQASAST----DGVDKLSG 888
Query: 184 DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSAS 243
+ K E +E ++ LK ++ V+ D +SD A + L
Sbjct: 889 KEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQ--------------DGLSDIAEKFLKKD 934
Query: 244 LGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKP-------ATDKDGK 296
+ DE ++K K G +++ PS+++ K + DG
Sbjct: 935 ----------------QSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGT 978
Query: 297 PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 356
LPE EE + I + D ++ K + +K E S A
Sbjct: 979 EKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYA------------ 1026
Query: 357 SMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGK--PVMDKVKEKAKE---E 411
E +T KG D+ ++ D K A + K ++ K K ++
Sbjct: 1027 ----------EKSTGKG----DSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSS 1072
Query: 412 DREKLGEKEETI-PPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQN 470
D EK KE+ D RL+ ++ ++ + L K + +++ S + SED +
Sbjct: 1073 DTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQ 1132
Query: 471 ASSLKFEDAKLAAAISEVV-SQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQP 529
+S K K A + E + ST + A +S SD + DD +S+G+
Sbjct: 1133 RTSSK----KKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDD-----QNSIGEGSS 1183
Query: 530 DPDENKPMEDKVKEKAKAEHRDKLGER--DDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS 587
D + KP+ + + + G+ ++P DDN + + E
Sbjct: 1184 DEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIK 1243
Query: 588 KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 647
+ D+D + + + +N ++ K +S +S +EE
Sbjct: 1244 ANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNS-----------ESDSDSEE 1292
Query: 648 TSKPK 652
+ KP+
Sbjct: 1293 SKKPR 1297
Score = 38.5 bits (88), Expect = 0.020
Identities = 77/407 (18%), Positives = 144/407 (35%), Gaps = 55/407 (13%)
Query: 270 KLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPR---------SESELIDELSE 320
KLEKCG E +E+ + + + LL E + + PR +E+ + S+
Sbjct: 585 KLEKCGLGQENSDNEHLV----ENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSD 640
Query: 321 DFDRSECKEK-----PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTV 375
+ KEK P + +K S +A P + ++ + + +
Sbjct: 641 EECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAIL 700
Query: 376 PDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDK 435
+ + + + S + + +K +A ++D+ K K T D+ + K K
Sbjct: 701 KEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDF--DTKKGK 758
Query: 436 DGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPAS 495
K + + K Q S ++ D++L I + A
Sbjct: 759 SAKSSIISKKKRQTQSESSNY---------------------DSELEKEIKSMSKIGAAR 797
Query: 496 TTQAGAPPR---DTSQSDKDLDDALDK-----LSDSLGQRQPDPDENKPMEDKVKEKAKA 547
TT+ P D+S+ +K +D L S D + + E +
Sbjct: 798 TTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTV 857
Query: 548 EHRDKLGERDDTIPPEYRHLLDDNGQDK-PVKPPTKKSEDSKKPADDQDPIDALSGDLDS 606
+ + E D +P + + +G DK K + S + +K A+ ++ L +
Sbjct: 858 DKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLK--TKT 915
Query: 607 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKD 653
C + + A+ KK S + + K S K TEE KP D
Sbjct: 916 CKKVQDGLSDIAEKFLKKDQSDETSEDD---KKQSKKGTEEKKKPSD 959
Score = 38.1 bits (87), Expect = 0.026
Identities = 111/569 (19%), Positives = 194/569 (34%), Gaps = 78/569 (13%)
Query: 7 KAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMI 66
K +K E + +S S + LP++ + + ++ S+K + +K +D +
Sbjct: 963 KVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDEL 1022
Query: 67 SAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDT---- 122
S E G G D ++KKS A E K K GKS DT
Sbjct: 1023 SDYAEKSTG----KGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYS 1078
Query: 123 ------------LGGPEETEEENTTY--TGPEVSDPMSSTYIEELG-------------K 155
L E E N + E+ SS+ EE K
Sbjct: 1079 MKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKK 1138
Query: 156 REVTIPPKYRELLAKPIGPD--DAIDALSSDFTCGSPTAAGKKTEKEESTE------VLK 207
+ V + K R L D + SSD + G+ + E+ + VL
Sbjct: 1139 KAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLS 1198
Query: 208 AQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAK 267
+ + S K V D D + E + +L S ++
Sbjct: 1199 SHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEP 1258
Query: 268 EEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSEC 327
EE ++ G+ +E P + K + + + EE KPR L+ D
Sbjct: 1259 EEGKKRTGKQNEENPGDEEAKNQVNSESDS---DSEESKKPRYRHRLLRHKLTVSDGESG 1315
Query: 328 KEKPSKPTEKTE--------------ESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKG 373
+EK +KP E E E + VSE V S P + K
Sbjct: 1316 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSE----SEDEQRPRTRSAKK 1371
Query: 374 TVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVK 433
++ + ++ ++ +K + +EE++E+ E+EE EE +
Sbjct: 1372 AELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE-----EEEEEE 1426
Query: 434 DKDGKPLLPKESKEQLPPMSEDFLL-----DALSEDFSGPQNASSLKFEDAKLAAAISEV 488
D++ P + ++++ + +D L +AL E+ + + + E KL EV
Sbjct: 1427 DENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKL----REV 1482
Query: 489 VSQTPASTTQAGAPPRDTSQSDKDLDDAL 517
+ AS T+ + D++ + L
Sbjct: 1483 IEIEDASPTKCPITTKLVLDEDEETKEPL 1511
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 54.7 bits (130), Expect = 3e-07
Identities = 136/665 (20%), Positives = 246/665 (36%), Gaps = 113/665 (16%)
Query: 10 KTEPEKKSQSTKP-KSLPKQASDTGSNDAHNKKAVS-RSAEQQPSEKSTEPKTKPQDMIS 67
KT + K+Q+ K K K+ S T +D KK S +S+ ++ T+ ++ D
Sbjct: 762 KTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYD--- 818
Query: 68 AGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTL--GG 125
E I ++S K G + KK + +S D+ K GMD + T G
Sbjct: 819 --SELEKEIKSMS-KIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGS 875
Query: 126 PEETE--EENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPIGPDDAIDALSS 183
++ E +E T++ E + +T +E + PK ++ A D +D LS
Sbjct: 876 SDDAERKQERETFSSAEGTVDKDTTIMELRDRL-----PKKQQASAST----DGVDKLSG 926
Query: 184 DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSAS 243
+ K E +E ++ LK ++ V+ D +SD A + L
Sbjct: 927 KEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQ--------------DGLSDIAEKFLKKD 972
Query: 244 LGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKP-------ATDKDGK 296
+ DE ++K K G +++ PS+++ K + DG
Sbjct: 973 ----------------QSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGT 1016
Query: 297 PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 356
LPE EE + I + D ++ K + +K E S A
Sbjct: 1017 EKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYA------------ 1064
Query: 357 SMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGK--PVMDKVKEKAKE---E 411
E +T KG D+ ++ D K A + K ++ K K ++
Sbjct: 1065 ----------EKSTGKG----DSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSS 1110
Query: 412 DREKLGEKEETI-PPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQN 470
D EK KE+ D RL+ ++ ++ + L K + +++ S + SED +
Sbjct: 1111 DTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQ 1170
Query: 471 ASSLKFEDAKLAAAISEVV-SQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQP 529
+S K K A + E + ST + A +S SD + DD +S+G+
Sbjct: 1171 RTSSK----KKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDD-----QNSIGEGSS 1221
Query: 530 DPDENKPMEDKVKEKAKAEHRDKLGER--DDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS 587
D + KP+ + + + G+ ++P DDN + + E
Sbjct: 1222 DEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIK 1281
Query: 588 KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 647
+ D+D + + + +N ++ K +S +S +EE
Sbjct: 1282 ANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNS-----------ESDSDSEE 1330
Query: 648 TSKPK 652
+ KP+
Sbjct: 1331 SKKPR 1335
Score = 38.5 bits (88), Expect = 0.020
Identities = 77/407 (18%), Positives = 144/407 (35%), Gaps = 55/407 (13%)
Query: 270 KLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPR---------SESELIDELSE 320
KLEKCG E +E+ + + + LL E + + PR +E+ + S+
Sbjct: 623 KLEKCGLGQENSDNEHLV----ENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSD 678
Query: 321 DFDRSECKEK-----PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTV 375
+ KEK P + +K S +A P + ++ + + +
Sbjct: 679 EECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAIL 738
Query: 376 PDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDK 435
+ + + + S + + +K +A ++D+ K K T D+ + K K
Sbjct: 739 KEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDF--DTKKGK 796
Query: 436 DGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPAS 495
K + + K Q S ++ D++L I + A
Sbjct: 797 SAKSSIISKKKRQTQSESSNY---------------------DSELEKEIKSMSKIGAAR 835
Query: 496 TTQAGAPPR---DTSQSDKDLDDALDK-----LSDSLGQRQPDPDENKPMEDKVKEKAKA 547
TT+ P D+S+ +K +D L S D + + E +
Sbjct: 836 TTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTV 895
Query: 548 EHRDKLGERDDTIPPEYRHLLDDNGQDK-PVKPPTKKSEDSKKPADDQDPIDALSGDLDS 606
+ + E D +P + + +G DK K + S + +K A+ ++ L +
Sbjct: 896 DKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLK--TKT 953
Query: 607 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKD 653
C + + A+ KK S + + K S K TEE KP D
Sbjct: 954 CKKVQDGLSDIAEKFLKKDQSDETSEDD---KKQSKKGTEEKKKPSD 997
Score = 38.1 bits (87), Expect = 0.026
Identities = 111/569 (19%), Positives = 194/569 (34%), Gaps = 78/569 (13%)
Query: 7 KAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMI 66
K +K E + +S S + LP++ + + ++ S+K + +K +D +
Sbjct: 1001 KVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDEL 1060
Query: 67 SAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDT---- 122
S E G G D ++KKS A E K K GKS DT
Sbjct: 1061 SDYAEKSTG----KGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYS 1116
Query: 123 ------------LGGPEETEEENTTY--TGPEVSDPMSSTYIEELG-------------K 155
L E E N + E+ SS+ EE K
Sbjct: 1117 MKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKK 1176
Query: 156 REVTIPPKYRELLAKPIGPD--DAIDALSSDFTCGSPTAAGKKTEKEESTE------VLK 207
+ V + K R L D + SSD + G+ + E+ + VL
Sbjct: 1177 KAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLS 1236
Query: 208 AQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAK 267
+ + S K V D D + E + +L S ++
Sbjct: 1237 SHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEP 1296
Query: 268 EEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSEC 327
EE ++ G+ +E P + K + + + EE KPR L+ D
Sbjct: 1297 EEGKKRTGKQNEENPGDEEAKNQVNSESDS---DSEESKKPRYRHRLLRHKLTVSDGESG 1353
Query: 328 KEKPSKPTEKTE--------------ESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKG 373
+EK +KP E E E + VSE V S P + K
Sbjct: 1354 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSE----SEDEQRPRTRSAKK 1409
Query: 374 TVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVK 433
++ + ++ ++ +K + +EE++E+ E+EE EE +
Sbjct: 1410 AELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE-----EEEEEE 1464
Query: 434 DKDGKPLLPKESKEQLPPMSEDFLL-----DALSEDFSGPQNASSLKFEDAKLAAAISEV 488
D++ P + ++++ + +D L +AL E+ + + + E KL EV
Sbjct: 1465 DENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKL----REV 1520
Query: 489 VSQTPASTTQAGAPPRDTSQSDKDLDDAL 517
+ AS T+ + D++ + L
Sbjct: 1521 IEIEDASPTKCPITTKLVLDEDEETKEPL 1549
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 54.7 bits (130), Expect = 3e-07
Identities = 146/698 (20%), Positives = 227/698 (32%), Gaps = 120/698 (17%)
Query: 10 KTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAG 69
K + E+ + K+ T + ++A + +A+ P ST D+ S+
Sbjct: 62 KRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSM 121
Query: 70 GESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEET 129
E T +GK G+ S+ ++ + SGKS +A TL ET
Sbjct: 122 KEKAKAETEKAGKTGN------SMPHPATGKTVANLLSGKSPRKSAEPSANTTL--VSET 173
Query: 130 EEENTTYTGPEVSDP-MSSTYIEELGKREVTIPPKYRELLAKPIGPDDAIDALSSDFTCG 188
EEE + + P M S + + + ++ KP + A SS T
Sbjct: 174 EEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKA-SSVSTKE 232
Query: 189 SPT--AAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 246
SP AA + + T +K + + A P+E+ E+ + S++ A GT
Sbjct: 233 SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEE-----EAPAGT 287
Query: 247 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 306
R + KA E+ L+ PA GK P P K
Sbjct: 288 RS--------------QVKASEKILQVRAAS----------APAKGTPGKGATPAPPGKA 323
Query: 307 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 366
+ + ED + S E+ S E+T +KA A S +TS SAP
Sbjct: 324 GAVASQTKAGKPEEDSESSS--EESSDSEEETPAAKALLQAKASG---KTSQVGAASAPA 378
Query: 367 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEK---EETI 423
+ + KG P A P P + K + +EED + E+ EE
Sbjct: 379 KESPRKGAAP---------------APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA 423
Query: 424 P---------PDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSL 474
P P R K+ P++ PP + + SS
Sbjct: 424 PAQAKPSGKAPQVRAASAPAKES----PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSS 479
Query: 475 KFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDEN 534
+ D+ A + +Q P T A +G P
Sbjct: 480 EESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 539
Query: 535 KPMEDKVKEKAKAEHRDKL-GERDDTIPPEYRHLLDDNGQDKPVKPPTK----------- 582
K ED E + E D GE + P L + Q KP P K
Sbjct: 540 KWEED--SESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAV 597
Query: 583 ------------KSEDSKKPADDQDPIDALSG----------DLDSCPSTTETSQNTAKD 620
SE+S AD ++ A++ +CP T T TA
Sbjct: 598 QVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNT---TASA 654
Query: 621 KCKKAASSSKAPKNGGKAKDSAKTTEE----TSKPKDD 654
K ++AP+ G A A ++ T +P +D
Sbjct: 655 KVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAED 692
Score = 53.1 bits (126), Expect = 8e-07
Identities = 133/677 (19%), Positives = 216/677 (31%), Gaps = 86/677 (12%)
Query: 3 PTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKP 62
P A + +P K TK + PK+ + T S K A R Q P + T
Sbjct: 624 PAAMTAAQAKPALKIPQTK--ACPKKTNTTASA----KVAPVRVGTQAPRKAGTATSPAG 677
Query: 63 QDMISAGGESVAGITAISGKPGDKKKEK----------KSLTPAVPVESKPDKPSGKSGM 112
AGG + S + D ++EK KS+ + V++ G G
Sbjct: 678 SSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQ 737
Query: 113 DAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKPI 172
A ++ GP T+ + E S+ S + +V K + A P
Sbjct: 738 GTA--PVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 795
Query: 173 GPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTM 232
A + G+ +A GK K +S V+ + + +
Sbjct: 796 -------AARAPSAKGTISAPGKVVTAAAQA---KQRSPSKVKPPVRNPQNSTVLARGPA 845
Query: 233 SDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATD 292
S ++ A+ Q PE D S +E +++ + E L + +T L PA +
Sbjct: 846 SVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKE 905
Query: 293 KDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEA 352
K P P K P + K+ S + + +S APA V+ A
Sbjct: 906 SPRKGAAPTPPGKTGPSAAQA-------------GKQDDSGSSSEESDSDGEAPAAVTSA 952
Query: 353 VCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEED 412
Q P P A A + + + P + + + E +
Sbjct: 953 ---------QVIKP-PLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESE 1002
Query: 413 REKLGEKEETIPPDYRLEEVKDKDGKP-LLPKESKEQLPPMSEDFLLDALSEDFSGPQNA 471
E + + + P R V P + PK S E +S+ A
Sbjct: 1003 DEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES---SRISDGKKQEGPA 1059
Query: 472 SSLKFEDAKLAAAISEVVSQTPASTTQAGAPP----RDTSQSDKDLDDALDKLSDSLGQR 527
+ + L A + S T + P + +++ + DD+ D S G
Sbjct: 1060 TQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSE 1119
Query: 528 QPD--PDENKPMEDKV-----KEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPP 580
+ P K V + + E DD + P L +G P P
Sbjct: 1120 EDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLL---SGYMTPGLTP 1176
Query: 581 TKKSEDSKKPADDQDPIDALSGDLDSCPSTTET----SQNTAKDKCK-KAASSSKAPKNG 635
P LDS PS + T K + K + A+ +PK G
Sbjct: 1177 ANSQASKATPK------------LDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTG 1224
Query: 636 GKAKDSAKTTEETSKPK 652
GK S T +++ KPK
Sbjct: 1225 GKEAASGTTPQKSRKPK 1241
Score = 34.3 bits (77), Expect = 0.37
Identities = 42/173 (24%), Positives = 71/173 (41%), Gaps = 18/173 (10%)
Query: 64 DMISAGGESVAGITAISGKPG--DKKKEKKSLTPAV--PVESKPDKPSGKSGMDAALDDL 119
+++ + V T S + G +K++ PA P K K G +A++
Sbjct: 1284 ELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVS-- 1341
Query: 120 IDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVT---IPPKYRELLAKPIGPDD 176
PE+T +TT G D S E+ GK + + E L K +G +
Sbjct: 1342 ------PEKT---STTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVE 1392
Query: 177 AIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEK 229
D + + +K +KE+ + KA+ A T S +P Q+KK+K +K
Sbjct: 1393 GGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1445
Score = 33.1 bits (74), Expect = 0.83
Identities = 120/633 (18%), Positives = 212/633 (33%), Gaps = 59/633 (9%)
Query: 41 KAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKE-KKSLTPAV-- 97
KAV+ +A+ Q + ++ + E++A + KP K + + +L PA
Sbjct: 852 KAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQV-----KPSGKTHQIRAALAPAKES 906
Query: 98 PVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKRE 157
P + P GK+G AA D G E + + P + T + +
Sbjct: 907 PRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDG-------EAPAAVTSAQVIKPPL 959
Query: 158 VTIPPKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGT---- 213
+ + P R P A A + S + A + + E +V+ A T
Sbjct: 960 IFVDPN-RSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIR 1018
Query: 214 VRSAAPPQEKKRKVEKDTMS--DQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKL 271
P R K +M+ + E+ S G +Q P +VD A
Sbjct: 1019 TNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPAT------QVDSA------- 1065
Query: 272 EKCGEDDETIPSEYRLKP-ATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEK 330
G T P ++ T+K KP LPE ++ K S+ ++ S+ SE +
Sbjct: 1066 --VGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGE 1123
Query: 331 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQS--APPEPATLKGTVPDDAVEALADSLG 388
+ + P+ V T+ S + P + L G + A +S
Sbjct: 1124 GPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA--NSQA 1181
Query: 389 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET---IPPDYRLEEVKDKDGKPLLPKES 445
K D P + + D ++ + ++ + P +E K
Sbjct: 1182 SKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK 1241
Query: 446 KEQLPPMSEDFLLDA-LSEDFSG---PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 501
K P + L + +++ G P N + ++ K+ + E + TT+ +
Sbjct: 1242 KGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESS 1301
Query: 502 PPRDTSQSDKDLDDA------LDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGE 555
S+ K D K LG + P + K KA+ RDK
Sbjct: 1302 RKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAK-RDKAS- 1359
Query: 556 RDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQ 615
D + + L G + +K + + D +P + S + +
Sbjct: 1360 -GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNP-KSKKEKKKSDKRKKDKEK 1417
Query: 616 NTAKDKCKKAASSSKAPKNGGKAKDSAKTTEET 648
K K KKA++ + K K KT E+T
Sbjct: 1418 KEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1450
Score = 30.0 bits (66), Expect = 7.0
Identities = 26/97 (26%), Positives = 35/97 (36%), Gaps = 13/97 (13%)
Query: 13 PEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGES 72
PEK S ++K K+ D S D KK Q ++ E K + G +S
Sbjct: 1342 PEKTSTTSKGKA----KRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQS 1397
Query: 73 VAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGK 109
P KK++KKS E K K K
Sbjct: 1398 ---------NPKSKKEKKKSDKRKKDKEKKEKKKKAK 1425
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.299 0.121 0.327
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,949,802
Number of Sequences: 37866
Number of extensions: 1678072
Number of successful extensions: 11381
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 95
Number of HSP's successfully gapped in prelim test: 851
Number of HSP's that attempted gapping in prelim test: 7680
Number of HSP's gapped (non-prelim): 3232
length of query: 654
length of database: 18,247,518
effective HSP length: 109
effective length of query: 545
effective length of database: 14,120,124
effective search space: 7695467580
effective search space used: 7695467580
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.