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Search of human proteins with 109637767
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109637767 calpastatin isoform j [Homo sapiens]
(667 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109637767 calpastatin isoform j [Homo sapiens] 1321 0.0
gi|109637759 calpastatin isoform f [Homo sapiens] 1321 0.0
gi|109637763 calpastatin isoform h [Homo sapiens] 1310 0.0
gi|27765085 calpastatin isoform b [Homo sapiens] 1310 0.0
gi|109637761 calpastatin isoform g [Homo sapiens] 1309 0.0
gi|109637765 calpastatin isoform i [Homo sapiens] 1297 0.0
gi|109637753 calpastatin isoform a [Homo sapiens] 1297 0.0
gi|109637771 calpastatin isoform l [Homo sapiens] 1286 0.0
gi|109637769 calpastatin isoform k [Homo sapiens] 1274 0.0
gi|109637757 calpastatin isoform e [Homo sapiens] 1274 0.0
gi|27765087 calpastatin isoform c [Homo sapiens] 781 0.0
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 91 3e-18
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 67 5e-11
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 67 5e-11
gi|150170670 piccolo isoform 2 [Homo sapiens] 64 4e-10
gi|150378539 piccolo isoform 1 [Homo sapiens] 64 4e-10
gi|104526627 triadin [Homo sapiens] 62 2e-09
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 61 3e-09
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 61 3e-09
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 61 3e-09
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 61 3e-09
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 61 3e-09
gi|109637791 transcription factor-like nuclear regulator [Homo s... 60 5e-09
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 59 1e-08
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 57 4e-08
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 57 7e-08
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 55 2e-07
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 55 2e-07
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 55 3e-07
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 54 5e-07
>gi|109637767 calpastatin isoform j [Homo sapiens]
Length = 667
Score = 1321 bits (3420), Expect = 0.0
Identities = 667/667 (100%), Positives = 667/667 (100%)
Query: 1 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT
Sbjct: 1 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
Query: 61 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI 120
KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI
Sbjct: 61 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI 120
Query: 121 DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPAD 180
DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPAD
Sbjct: 121 DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPAD 180
Query: 181 SSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV 240
SSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV
Sbjct: 181 SSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV 240
Query: 241 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 300
EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL
Sbjct: 241 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 300
Query: 301 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA 360
KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA
Sbjct: 301 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA 360
Query: 361 PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK 420
PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK
Sbjct: 361 PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK 420
Query: 421 AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG 480
AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG
Sbjct: 421 AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG 480
Query: 481 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR 540
PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR
Sbjct: 481 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR 540
Query: 541 QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS 600
QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS
Sbjct: 541 QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS 600
Query: 601 KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 660
KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE
Sbjct: 601 KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 660
Query: 661 TSKPKDD 667
TSKPKDD
Sbjct: 661 TSKPKDD 667
>gi|109637759 calpastatin isoform f [Homo sapiens]
Length = 750
Score = 1321 bits (3420), Expect = 0.0
Identities = 667/667 (100%), Positives = 667/667 (100%)
Query: 1 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT
Sbjct: 84 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 143
Query: 61 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI 120
KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI
Sbjct: 144 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI 203
Query: 121 DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPAD 180
DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPAD
Sbjct: 204 DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPAD 263
Query: 181 SSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV 240
SSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV
Sbjct: 264 SSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV 323
Query: 241 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 300
EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL
Sbjct: 324 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 383
Query: 301 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA 360
KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA
Sbjct: 384 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA 443
Query: 361 PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK 420
PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK
Sbjct: 444 PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK 503
Query: 421 AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG 480
AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG
Sbjct: 504 AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG 563
Query: 481 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR 540
PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR
Sbjct: 564 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR 623
Query: 541 QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS 600
QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS
Sbjct: 624 QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS 683
Query: 601 KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 660
KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE
Sbjct: 684 KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 743
Query: 661 TSKPKDD 667
TSKPKDD
Sbjct: 744 TSKPKDD 750
Score = 79.7 bits (195), Expect = 8e-15
Identities = 88/362 (24%), Positives = 152/362 (41%), Gaps = 42/362 (11%)
Query: 312 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEK--TEESKAAAPAPVSEAVC 367
+ +P +KP PR + + + E PSKP EK ++E KAA
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAA---------- 50
Query: 368 RTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEA-DPEDGKPVMDKVKEKAKEEDR 426
S+ S+ GT V A + + K + +P + K V + ++K++
Sbjct: 51 -----SLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQ---- 101
Query: 427 EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASS 486
K +++P D K + + +++Q S + +G ++ +
Sbjct: 102 ---STKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAG 158
Query: 487 LKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDE 546
+ K E S TPA ++ P + + +S +D ALD L D+LG + +E
Sbjct: 159 ITAISGKPGDKKKEKKSLTPAVPVES-KPDKPSGKS--GMDAALDDLIDTLGGPEETEEE 215
Query: 547 NKPME-DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPAD 605
N +V + + + ++LG+R+ TIPP+YR LL ++ PP DS KP
Sbjct: 216 NTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITGPPA----DSSKPIG 269
Query: 606 DQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPK 665
D IDALS D +C S T + T K++ + + A G + +A E+ K +
Sbjct: 270 PDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRKVE 324
Query: 666 DD 667
D
Sbjct: 325 KD 326
>gi|109637763 calpastatin isoform h [Homo sapiens]
Length = 769
Score = 1310 bits (3390), Expect = 0.0
Identities = 667/686 (97%), Positives = 667/686 (97%), Gaps = 19/686 (2%)
Query: 1 MNPTETKAVKTEPEKKSQSTK-------------------PKSLPKQASDTGSNDAHNKK 41
MNPTETKAVKTEPEKKSQSTK PKSLPKQASDTGSNDAHNKK
Sbjct: 84 MNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKK 143
Query: 42 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 101
AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES
Sbjct: 144 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 203
Query: 102 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 161
KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP
Sbjct: 204 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 263
Query: 162 PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 221
PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA
Sbjct: 264 PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 323
Query: 222 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 281
QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE
Sbjct: 324 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 383
Query: 282 EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK 341
EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK
Sbjct: 384 EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK 443
Query: 342 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 401
EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG
Sbjct: 444 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 503
Query: 402 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 461
KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ
Sbjct: 504 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 563
Query: 462 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 521
LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ
Sbjct: 564 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 623
Query: 522 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 581
SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL
Sbjct: 624 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 683
Query: 582 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 641
DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS
Sbjct: 684 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 743
Query: 642 SKAPKNGGKAKDSAKTTEETSKPKDD 667
SKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 744 SKAPKNGGKAKDSAKTTEETSKPKDD 769
Score = 89.4 bits (220), Expect = 1e-17
Identities = 87/359 (24%), Positives = 148/359 (41%), Gaps = 17/359 (4%)
Query: 312 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 369
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 370 SMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKL 429
SA A+ T ++ K E + + + V EK +E + K
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKE 120
Query: 430 GEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKF 489
+ +++P D K + + +++Q S + +G ++ + +
Sbjct: 121 HTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA 180
Query: 490 EDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKP 549
K E S TPA ++ P + + +S +D ALD L D+LG + +EN
Sbjct: 181 ISGKPGDKKKEKKSLTPAVPVES-KPDKPSGKS--GMDAALDDLIDTLGGPEETEEENTT 237
Query: 550 ME-DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQD 608
+V + + + ++LG+R+ TIPP+YR LL ++ PP DS KP D
Sbjct: 238 YTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITGPPA----DSSKPIGPDD 291
Query: 609 PIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 667
IDALS D +C S T + T K++ + + A G + +A E+ K + D
Sbjct: 292 AIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRKVEKD 345
>gi|27765085 calpastatin isoform b [Homo sapiens]
Length = 686
Score = 1310 bits (3390), Expect = 0.0
Identities = 667/686 (97%), Positives = 667/686 (97%), Gaps = 19/686 (2%)
Query: 1 MNPTETKAVKTEPEKKSQSTK-------------------PKSLPKQASDTGSNDAHNKK 41
MNPTETKAVKTEPEKKSQSTK PKSLPKQASDTGSNDAHNKK
Sbjct: 1 MNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKK 60
Query: 42 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 101
AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES
Sbjct: 61 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 120
Query: 102 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 161
KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP
Sbjct: 121 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 180
Query: 162 PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 221
PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA
Sbjct: 181 PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 240
Query: 222 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 281
QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE
Sbjct: 241 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 300
Query: 282 EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK 341
EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK
Sbjct: 301 EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK 360
Query: 342 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 401
EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG
Sbjct: 361 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 420
Query: 402 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 461
KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ
Sbjct: 421 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 480
Query: 462 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 521
LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ
Sbjct: 481 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 540
Query: 522 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 581
SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL
Sbjct: 541 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 600
Query: 582 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 641
DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS
Sbjct: 601 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 660
Query: 642 SKAPKNGGKAKDSAKTTEETSKPKDD 667
SKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 661 SKAPKNGGKAKDSAKTTEETSKPKDD 686
>gi|109637761 calpastatin isoform g [Homo sapiens]
Length = 772
Score = 1309 bits (3387), Expect = 0.0
Identities = 667/689 (96%), Positives = 667/689 (96%), Gaps = 22/689 (3%)
Query: 1 MNPTETKA----------------------VKTEPEKKSQSTKPKSLPKQASDTGSNDAH 38
MNPTETKA VKTEPEKKSQSTKPKSLPKQASDTGSNDAH
Sbjct: 84 MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKPKSLPKQASDTGSNDAH 143
Query: 39 NKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVP 98
NKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVP
Sbjct: 144 NKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVP 203
Query: 99 VESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREV 158
VESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREV
Sbjct: 204 VESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREV 263
Query: 159 TIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEV 218
TIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEV
Sbjct: 264 TIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEV 323
Query: 219 LKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAK 278
LKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAK
Sbjct: 324 LKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAK 383
Query: 279 AKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRS 338
AKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRS
Sbjct: 384 AKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRS 443
Query: 339 ECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALAD 398
ECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALAD
Sbjct: 444 ECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALAD 503
Query: 399 SLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES 458
SLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES
Sbjct: 504 SLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES 563
Query: 459 KEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD 518
KEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD
Sbjct: 564 KEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD 623
Query: 519 TSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYR 578
TSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYR
Sbjct: 624 TSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYR 683
Query: 579 HLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKA 638
HLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKA
Sbjct: 684 HLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKA 743
Query: 639 ASSSKAPKNGGKAKDSAKTTEETSKPKDD 667
ASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 744 ASSSKAPKNGGKAKDSAKTTEETSKPKDD 772
Score = 224 bits (570), Expect = 3e-58
Identities = 195/664 (29%), Positives = 315/664 (47%), Gaps = 82/664 (12%)
Query: 40 KKAVSRSAEQQPSEKSTEPKTKPQD-------------------MISAGGESVAGITAIS 80
+ A +R + SEK++E +KP + + G S ++A S
Sbjct: 16 RAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASS 75
Query: 81 GKPGDKKKEKKSLTPAVPVESK---PDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYT 137
G + T A+PV + P P+ K A+ +TE E + +
Sbjct: 76 GATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAV-----------KTEPEKKSQS 124
Query: 138 GPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKP-IGPDDAIDALSS 196
S P ++ + G + + + + P S++P P D I A
Sbjct: 125 TKPKSLPKQAS---DTGSNDA-----HNKKAVSRSAEQQPSEKSTEPKTKPQDMISA-GG 175
Query: 197 DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSAS 256
+ G +GK +K++ + ++ A P + K K + D AL+ L +
Sbjct: 176 ESVAGITAISGKPGDKKKEKK--------SLTPAVPVESKPDKPSGKSGMDAALDDLIDT 227
Query: 257 L-GTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEP 315
L G + E E + EV + + +E+ G+ + TIP +YR + K+G + P
Sbjct: 228 LGGPEETEEENTTYTGPEVSDPMS-STYIEELGKREVTIPPKYR-ELLAKKEG--ITGPP 283
Query: 316 EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ 375
+ KP + ID LS DF P+ +KTE+ ++ +E + S +++
Sbjct: 284 ADSSKPIGPDDAIDALSSDFTCG----SPTAAGKKTEKEES------TEVLKAQSAGTVR 333
Query: 376 SAPP----EPATLKGTVPDDAVEALADSLGKKEADPE-DGKPVMDKVKEKAKEEDREKLG 430
SA P + K T+ D A+EAL+ SLG ++A+PE D + + + + KAKEE EK G
Sbjct: 334 SAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG 393
Query: 431 EKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQ-----NAS 485
E +ETIP +YRL+ DKDGKPLLP E +E+ P SE L+D LSEDF + +
Sbjct: 394 EDDETIPSEYRLKPATDKDGKPLLP-EPEEKPKPRSESELIDELSEDFDRSECKEKPSKP 452
Query: 486 SLKFEDAKLA--AAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPD 543
+ K E++K A A +SE V +T + Q+ APP + DDA++ L+DSLG+++ D
Sbjct: 453 TEKTEESKAAAPAPVSEAVCRTSMCSIQS-APPEPATLKGTVPDDAVEALADSLGKKEAD 511
Query: 544 PDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKP 603
P++ KP+ DKVKEKAK E R+KLGE+++TIPP+YR + KP+ P K+S++ P
Sbjct: 512 PEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLP--KESKEQLPP 569
Query: 604 ADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSK 663
+ +DALS D + + AK + S+ P + +A + T ++ K
Sbjct: 570 MSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDK 629
Query: 664 PKDD 667
DD
Sbjct: 630 DLDD 633
Score = 81.3 bits (199), Expect = 3e-15
Identities = 90/364 (24%), Positives = 153/364 (42%), Gaps = 24/364 (6%)
Query: 312 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 369
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 370 SMCSIQSAPPEPATLKGTVPDDAV---EALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 426
SA A+ T ++ E A + ++ P P K K++A + +
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPH--LPNKKKHKKQAVKTEP 118
Query: 427 EKLGE--KEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNA 484
EK + K +++P D K + + +++Q S + +G ++
Sbjct: 119 EKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESV 178
Query: 485 SSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDP 544
+ + K E S TPA ++ P + + +S +D ALD L D+LG +
Sbjct: 179 AGITAISGKPGDKKKEKKSLTPAVPVES-KPDKPSGKS--GMDAALDDLIDTLGGPEETE 235
Query: 545 DENKPME-DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKP 603
+EN +V + + + ++LG+R+ TIPP+YR LL ++ PP DS KP
Sbjct: 236 EENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITGPPA----DSSKP 289
Query: 604 ADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSK 663
D IDALS D +C S T + T K++ + + A G + +A E+ K
Sbjct: 290 IGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRK 344
Query: 664 PKDD 667
+ D
Sbjct: 345 VEKD 348
>gi|109637765 calpastatin isoform i [Homo sapiens]
Length = 708
Score = 1297 bits (3357), Expect = 0.0
Identities = 667/708 (94%), Positives = 667/708 (94%), Gaps = 41/708 (5%)
Query: 1 MNPTETKA----------------------VKTEPEKKSQSTK----------------- 21
MNPTETKA VKTEPEKKSQSTK
Sbjct: 1 MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEH 60
Query: 22 --PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 79
PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI
Sbjct: 61 TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 120
Query: 80 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 139
SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP
Sbjct: 121 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 180
Query: 140 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 199
EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT
Sbjct: 181 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 240
Query: 200 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 259
CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT
Sbjct: 241 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 300
Query: 260 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 319
RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP
Sbjct: 301 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 360
Query: 320 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 379
KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP
Sbjct: 361 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 420
Query: 380 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 439
EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD
Sbjct: 421 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 480
Query: 440 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 499
YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS
Sbjct: 481 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 540
Query: 500 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 559
EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK
Sbjct: 541 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 600
Query: 560 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 619
AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS
Sbjct: 601 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 660
Query: 620 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 667
CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 661 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 708
>gi|109637753 calpastatin isoform a [Homo sapiens]
Length = 791
Score = 1297 bits (3357), Expect = 0.0
Identities = 667/708 (94%), Positives = 667/708 (94%), Gaps = 41/708 (5%)
Query: 1 MNPTETKA----------------------VKTEPEKKSQSTK----------------- 21
MNPTETKA VKTEPEKKSQSTK
Sbjct: 84 MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEH 143
Query: 22 --PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 79
PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI
Sbjct: 144 TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 203
Query: 80 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 139
SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP
Sbjct: 204 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 263
Query: 140 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 199
EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT
Sbjct: 264 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 323
Query: 200 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 259
CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT
Sbjct: 324 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 383
Query: 260 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 319
RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP
Sbjct: 384 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 443
Query: 320 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 379
KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP
Sbjct: 444 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 503
Query: 380 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 439
EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD
Sbjct: 504 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 563
Query: 440 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 499
YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS
Sbjct: 564 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 623
Query: 500 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 559
EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK
Sbjct: 624 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 683
Query: 560 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 619
AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS
Sbjct: 684 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 743
Query: 620 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 667
CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 744 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 791
Score = 221 bits (564), Expect = 1e-57
Identities = 196/668 (29%), Positives = 315/668 (47%), Gaps = 71/668 (10%)
Query: 40 KKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPV 99
+ A +R + SEK++E +KP + + + A + G + A V
Sbjct: 16 RAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASL----GSSQSSRTYAGGTASATKV 71
Query: 100 ESKPDKPSGKSGMDAALDDLI---DTLGGP----EETEEENTTYTGPEVSDPMSSTYIEE 152
+ S S M+ I + GP ++ ++ T PE + +
Sbjct: 72 SASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVH 131
Query: 153 LGKREVTIPPKYRE--LLAKKEGITG-----------------PPADSSKP-IGPDDAID 192
K + P ++ E L K+ TG P S++P P D I
Sbjct: 132 EKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMIS 191
Query: 193 ALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEA 252
A + G +GK +K++ + ++ A P + K K + D AL+
Sbjct: 192 A-GGESVAGITAISGKPGDKKKEKK--------SLTPAVPVESKPDKPSGKSGMDAALDD 242
Query: 253 LSASL-GTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPL 311
L +L G + E E + EV + + +E+ G+ + TIP +YR + K+G +
Sbjct: 243 LIDTLGGPEETEEENTTYTGPEVSDPMS-STYIEELGKREVTIPPKYR-ELLAKKEG--I 298
Query: 312 LPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSM 371
P + KP + ID LS DF P+ +KTE+ ++ +E + S
Sbjct: 299 TGPPADSSKPIGPDDAIDALSSDFTCG----SPTAAGKKTEKEES------TEVLKAQSA 348
Query: 372 CSIQSAPP----EPATLKGTVPDDAVEALADSLGKKEADPE-DGKPVMDKVKEKAKEEDR 426
+++SA P + K T+ D A+EAL+ SLG ++A+PE D + + + + KAKEE
Sbjct: 349 GTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKL 408
Query: 427 EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQ---- 482
EK GE +ETIP +YRL+ DKDGKPLLP E +E+ P SE L+D LSEDF +
Sbjct: 409 EKCGEDDETIPSEYRLKPATDKDGKPLLP-EPEEKPKPRSESELIDELSEDFDRSECKEK 467
Query: 483 -NASSLKFEDAKLA--AAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQ 539
+ + K E++K A A +SE V +T + Q+ APP + DDA++ L+DSLG+
Sbjct: 468 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQS-APPEPATLKGTVPDDAVEALADSLGK 526
Query: 540 RQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSED 599
++ DP++ KP+ DKVKEKAK E R+KLGE+++TIPP+YR + KP+ P K+S++
Sbjct: 527 KEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLP--KESKE 584
Query: 600 SKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTE 659
P + +DALS D + + AK + S+ P + +A + T
Sbjct: 585 QLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTS 644
Query: 660 ETSKPKDD 667
++ K DD
Sbjct: 645 QSDKDLDD 652
Score = 80.9 bits (198), Expect = 4e-15
Identities = 100/387 (25%), Positives = 162/387 (41%), Gaps = 51/387 (13%)
Query: 312 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 369
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 370 SMCSIQSAPPEPATLKGTVPDDAV---EALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 426
SA A+ T ++ E A + ++ P P K K++A + +
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPH--LPNKKKHKKQAVKTEP 118
Query: 427 EKLGEKEETIPPDYRLEEVKDKDGKP-------LLPKE----------SKEQLPPMSEDF 469
EK + + + E K ++GKP LPK+ +K+ + +E
Sbjct: 119 EKKSQSTKLSV----VHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQ 174
Query: 470 LLDALSEDFSGPQNASSLKFEDAKLAAAIS--------EVVSQTPASTTQAGAPPRDTSQ 521
+ +E + PQ+ S E AIS E S TPA ++ P + + +
Sbjct: 175 PSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES-KPDKPSGK 233
Query: 522 SDKDLDDALDKLSDSLGQRQPDPDENKPME-DKVKEKAKAEHRDKLGERDDTIPPEYRHL 580
S +D ALD L D+LG + +EN +V + + + ++LG+R+ TIPP+YR L
Sbjct: 234 S--GMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYREL 291
Query: 581 LDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAAS 640
L ++ PP DS KP D IDALS D +C S T + T K++ +
Sbjct: 292 LAK--KEGITGPPA----DSSKPIGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLK 344
Query: 641 SSKAPKNGGKAKDSAKTTEETSKPKDD 667
+ A G + +A E+ K + D
Sbjct: 345 AQSA----GTVRSAAPPQEKKRKVEKD 367
>gi|109637771 calpastatin isoform l [Homo sapiens]
Length = 654
Score = 1286 bits (3328), Expect = 0.0
Identities = 654/667 (98%), Positives = 654/667 (98%), Gaps = 13/667 (1%)
Query: 1 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT
Sbjct: 1 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
Query: 61 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI 120
KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI
Sbjct: 61 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI 120
Query: 121 DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPAD 180
DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK
Sbjct: 121 DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK---------- 170
Query: 181 SSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV 240
PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV
Sbjct: 171 ---PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV 227
Query: 241 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 300
EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL
Sbjct: 228 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 287
Query: 301 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA 360
KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA
Sbjct: 288 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA 347
Query: 361 PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK 420
PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK
Sbjct: 348 PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK 407
Query: 421 AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG 480
AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG
Sbjct: 408 AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG 467
Query: 481 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR 540
PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR
Sbjct: 468 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR 527
Query: 541 QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS 600
QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS
Sbjct: 528 QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS 587
Query: 601 KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 660
KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE
Sbjct: 588 KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 647
Query: 661 TSKPKDD 667
TSKPKDD
Sbjct: 648 TSKPKDD 654
>gi|109637769 calpastatin isoform k [Homo sapiens]
Length = 673
Score = 1275 bits (3298), Expect = 0.0
Identities = 654/686 (95%), Positives = 654/686 (95%), Gaps = 32/686 (4%)
Query: 1 MNPTETKAVKTEPEKKSQSTK-------------------PKSLPKQASDTGSNDAHNKK 41
MNPTETKAVKTEPEKKSQSTK PKSLPKQASDTGSNDAHNKK
Sbjct: 1 MNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKK 60
Query: 42 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 101
AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES
Sbjct: 61 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 120
Query: 102 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 161
KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP
Sbjct: 121 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 180
Query: 162 PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 221
PKYRELLAK PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA
Sbjct: 181 PKYRELLAK-------------PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 227
Query: 222 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 281
QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE
Sbjct: 228 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 287
Query: 282 EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK 341
EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK
Sbjct: 288 EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK 347
Query: 342 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 401
EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG
Sbjct: 348 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 407
Query: 402 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 461
KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ
Sbjct: 408 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 467
Query: 462 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 521
LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ
Sbjct: 468 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 527
Query: 522 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 581
SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL
Sbjct: 528 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 587
Query: 582 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 641
DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS
Sbjct: 588 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 647
Query: 642 SKAPKNGGKAKDSAKTTEETSKPKDD 667
SKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 648 SKAPKNGGKAKDSAKTTEETSKPKDD 673
>gi|109637757 calpastatin isoform e [Homo sapiens]
Length = 756
Score = 1275 bits (3298), Expect = 0.0
Identities = 654/686 (95%), Positives = 654/686 (95%), Gaps = 32/686 (4%)
Query: 1 MNPTETKAVKTEPEKKSQSTK-------------------PKSLPKQASDTGSNDAHNKK 41
MNPTETKAVKTEPEKKSQSTK PKSLPKQASDTGSNDAHNKK
Sbjct: 84 MNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKK 143
Query: 42 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 101
AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES
Sbjct: 144 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 203
Query: 102 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 161
KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP
Sbjct: 204 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 263
Query: 162 PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 221
PKYRELLAK PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA
Sbjct: 264 PKYRELLAK-------------PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 310
Query: 222 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 281
QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE
Sbjct: 311 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 370
Query: 282 EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK 341
EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK
Sbjct: 371 EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK 430
Query: 342 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 401
EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG
Sbjct: 431 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 490
Query: 402 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 461
KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ
Sbjct: 491 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 550
Query: 462 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 521
LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ
Sbjct: 551 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 610
Query: 522 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 581
SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL
Sbjct: 611 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 670
Query: 582 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 641
DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS
Sbjct: 671 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 730
Query: 642 SKAPKNGGKAKDSAKTTEETSKPKDD 667
SKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 731 SKAPKNGGKAKDSAKTTEETSKPKDD 756
Score = 81.6 bits (200), Expect = 2e-15
Identities = 83/359 (23%), Positives = 142/359 (39%), Gaps = 30/359 (8%)
Query: 312 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 369
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 370 SMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKL 429
SA A+ T ++ K E + + + V EK +E + K
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKE 120
Query: 430 GEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKF 489
+ +++P D K + + +++Q S + +G ++ + +
Sbjct: 121 HTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA 180
Query: 490 EDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKP 549
K E S TPA ++ P + + +S +D ALD L D+LG + +EN
Sbjct: 181 ISGKPGDKKKEKKSLTPAVPVES-KPDKPSGKS--GMDAALDDLIDTLGGPEETEEENTT 237
Query: 550 ME-DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQD 608
+V + + + ++LG+R+ TIPP+YR LL KP D
Sbjct: 238 YTGPEVSDPMSSTYIEELGKREVTIPPKYRELL-------------------AKPIGPDD 278
Query: 609 PIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 667
IDALS D +C S T + T K++ + + A G + +A E+ K + D
Sbjct: 279 AIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRKVEKD 332
>gi|27765087 calpastatin isoform c [Homo sapiens]
Length = 430
Score = 781 bits (2017), Expect = 0.0
Identities = 391/393 (99%), Positives = 392/393 (99%), Gaps = 1/393 (0%)
Query: 275 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 334
D+AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED
Sbjct: 39 DQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 98
Query: 335 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 394
FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE
Sbjct: 99 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 158
Query: 395 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 454
ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL
Sbjct: 159 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 218
Query: 455 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 514
PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA
Sbjct: 219 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 278
Query: 515 PPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 574
PPRDTS SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP
Sbjct: 279 PPRDTS-SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 337
Query: 575 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 634
PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK
Sbjct: 338 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 397
Query: 635 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 667
CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 398 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
Score = 206 bits (525), Expect = 4e-53
Identities = 144/396 (36%), Positives = 213/396 (53%), Gaps = 30/396 (7%)
Query: 150 IEELGKREVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDALSSDFTCGSPTAA 206
+E+ G+ + TIP +YR + K+G + P + KP + ID LS DF
Sbjct: 48 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSE--CK 105
Query: 207 GKKTEKEESTEVLKAQSAGTVRSA-----------APPQEKKRKVEKDTMSDQALEALSA 255
K ++ E TE KA + V A APP+ K T+ D A+EAL+
Sbjct: 106 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLK---GTVPDDAVEALAD 162
Query: 256 SLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-E 314
SLG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E
Sbjct: 163 SLGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKE 221
Query: 315 PEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSI 374
+E+ P SE L+D LSEDF + + + K E++K A A +SE V +T +
Sbjct: 222 SKEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTT 274
Query: 375 QSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEE 434
Q+ P T DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++
Sbjct: 275 QAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDD 334
Query: 435 TIPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDA 492
TIPP+YR + KP+ P K+S++ P + +DALS D + + A
Sbjct: 335 TIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTA 394
Query: 493 KLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 528
K + S+ P + +A + T ++ K DD
Sbjct: 395 KDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
Score = 122 bits (306), Expect = 1e-27
Identities = 100/301 (33%), Positives = 150/301 (49%), Gaps = 31/301 (10%)
Query: 82 KPGDKKKEKKSLTPA-----------VPVESKPDKPSGKSGM--DAALDDLIDTLGGPEE 128
KP +K +E K+ PA ++S P +P+ G D A++ L D+LG +E
Sbjct: 110 KPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG-KKE 168
Query: 129 TEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYR-ELLAKKEGITGPPADSSK---P 184
+ E+ +V + E+LG++E TIPP YR E + K+G P +S + P
Sbjct: 169 ADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPP 228
Query: 185 IGPDDAIDALSSDFTCGSPTAAGKKTEKEE----STEVLKAQSAGTVRSAAPPQEKKRKV 240
+ D +DALS DF+ G A+ K E + +EV+ A T ++ APP R
Sbjct: 229 MSEDFLLDALSEDFS-GPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPP----RDT 283
Query: 241 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 300
D D AL+ LS SLG RQ +P+ + + +++ + KAK E +K GE D+TIP EYR
Sbjct: 284 SSDKDLDDALDKLSDSLGQRQPDPD-ENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRH 342
Query: 301 ---KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAA 357
DK KP + E+ KP + + ID LS D D + S+ T K + KAA
Sbjct: 343 LLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAA 402
Query: 358 A 358
+
Sbjct: 403 S 403
Score = 71.2 bits (173), Expect = 3e-12
Identities = 66/256 (25%), Positives = 112/256 (43%), Gaps = 16/256 (6%)
Query: 1 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
M+ + KA + + EK + K +++P D K + + +++Q S +
Sbjct: 178 MDKVKEKAKEEDREKLGE--KEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLL 235
Query: 61 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES--KPDKPSGKSGMDAALDD 118
+G ++ + + K E S TPA ++ P S +D ALD
Sbjct: 236 DALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDK 295
Query: 119 LIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITG 176
L D+LG + +EN +V + + + ++LG+R+ TIPP+YR LL ++
Sbjct: 296 LSDSLGQRQPDPDENKPMED-KVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVK 354
Query: 177 PPA----DSSKPIGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTV 227
PP DS KP D IDALS D +C S T + T K++ + + A G
Sbjct: 355 PPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKA 414
Query: 228 RSAAPPQEKKRKVEKD 243
+ +A E+ K + D
Sbjct: 415 KDSAKTTEETSKPKDD 430
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 91.3 bits (225), Expect = 3e-18
Identities = 138/596 (23%), Positives = 225/596 (37%), Gaps = 57/596 (9%)
Query: 95 PAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELG 154
P +P S K + + +T+ E+TEE T EV++ EE G
Sbjct: 427 PKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVT---EEVTEEEEKEAKEEEG 483
Query: 155 KREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEE 214
K E + E +E PPA+ + P+ +A S A K EKEE
Sbjct: 484 KEEEG--GEEEEAEGGEEETKSPPAEEAA--SPEK--EAKSPVKEEAKSPAEAKSPEKEE 537
Query: 215 STEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEV 274
+ + +S +S A + K K ++A + P + K
Sbjct: 538 AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKE--EAKSP 595
Query: 275 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 334
EAK+ E+ E+ ++ P+E + + + PE+ P E E ++
Sbjct: 596 AEAKSPEKAKSPVKEEAKS-PAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654
Query: 335 FDRSECK--EKPSKPTEKTEESKAAAPAPV-SEAVCRTSMCS-IQSAPPEPATLKGTVPD 390
++ E K EK P + +S A +PV +EA S ++ P K V +
Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714
Query: 391 DAVEA-LADSLGKKEAD-PEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDK 448
+A A S K+EA PE K VKE+AK ++ K EK +T+ +VK
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAK---SPVKEEAKSPEKAKSPEKAKTL-------DVKSP 764
Query: 449 DGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAA--------AISE 500
+ K +E++ E + E+ P+ A S EDAK S
Sbjct: 765 EAKTPAKEEARSPADKFPEK-AKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823
Query: 501 VVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKA-- 558
V + + PP+ + ++ DS + P + KP ++ KE A
Sbjct: 824 VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE 883
Query: 559 -----KAEHRDKLGERDDTIP-PEYRHLLDDNGQDKPVKPPTKKSEDSKKPAD--DQDPI 610
K E + + E +P PE ++ P K K+ K+ + ++P
Sbjct: 884 KPKESKVEAKKEEAEDKKKVPTPE---------KEAPAKVEVKEDAKPKEKTEVAKKEPD 934
Query: 611 DALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKT-TEETSKPK 665
DA + + E + K +KA + PK KAK+ KT ++E SKPK
Sbjct: 935 DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPK 990
Score = 85.1 bits (209), Expect = 2e-16
Identities = 122/528 (23%), Positives = 208/528 (39%), Gaps = 67/528 (12%)
Query: 164 YRELLAKKEGITG-PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQ 222
YR+LL +E G P S P G I ++S+ S + E+ T +++ Q
Sbjct: 402 YRKLLEGEECRIGFGPIPFSLPEGLPK-IPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQ 460
Query: 223 SAGT-VRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQ---------AEPELDLRS-I 271
+ T V +E+K E++ ++ E A G + A PE + +S +
Sbjct: 461 TEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPV 520
Query: 272 KEVDE--AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELID 329
KE + A+AK + E+ E E PA ++ P + EK + +S +E+
Sbjct: 521 KEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEV-- 578
Query: 330 ELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVP 389
S + +S KE+ P E KA +P ++ PA K V
Sbjct: 579 -KSPEKAKSPAKEEAKSPAEAKSPEKAKSP--------------VKEEAKSPAEAKSPVK 623
Query: 390 DDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKD 449
++A K A+ + + KE+AK ++ K EKEE P+ VK +
Sbjct: 624 EEA---------KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674
Query: 450 GKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPAST 509
P K S + S + + E+ P+ A S E+AK V + +
Sbjct: 675 KSPEKAK-SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTP 733
Query: 510 TQAGAPPRDTSQSD---------KDLDDALDKLSDSLGQRQPDPDENKPMEDK--VKEKA 558
+A +P ++ ++S K LD + + P + P + K VKE+
Sbjct: 734 EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEV 793
Query: 559 KAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLD 618
K+ + K ++D PE + + + VK P K+ E ++ + P A + +
Sbjct: 794 KSPEKAKSPLKEDAKAPE-----KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA---EEE 845
Query: 619 SCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKD 666
P+T +T + KD K+ A +AP K K K KPK+
Sbjct: 846 KAPATPKTEEK--KDSKKEEAPKKEAP----KPKVEEKKEPAVEKPKE 887
Score = 80.5 bits (197), Expect = 5e-15
Identities = 142/613 (23%), Positives = 232/613 (37%), Gaps = 84/613 (13%)
Query: 6 TKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDM 65
T+ V E EK+++ + K + + + + P+E++ P+ + +
Sbjct: 467 TEEVTEEEEKEAKEEEGK-------EEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSP 519
Query: 66 ISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESK-PDKPSGKSGMDAALDDLIDTLG 124
+ +S A K +K++ K P ++K P K KS +A
Sbjct: 520 VKEEAKSPA-----EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK--------- 565
Query: 125 GPEETEEENTTYTGPEVSDP--MSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSS 182
PE+ E ++ EV P S EE P+ + K+E + PA++
Sbjct: 566 SPEKEEAKSPA----EVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS--PAEAK 619
Query: 183 KPIGPDDAIDA-LSSDFTCGSPTAA-GKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV 240
P+ + A + S SPT K EK +S E +A+S +S + K +
Sbjct: 620 SPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEK 679
Query: 241 EKDTMSDQALEALSASLGTRQA--EPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEY 298
K + +A A ++ PE +KE EAK+ E+ E+ +T E
Sbjct: 680 AKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE--EAKSPEKAKSPVKEEAKT--PEK 735
Query: 299 RLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAA 358
P ++ P EK K +++ +D S + ++ KE+ P +K E A
Sbjct: 736 AKSPVKEEAKSP------EKAKSPEKAKTLDVKSPEA-KTPAKEEARSPADKFPEK---A 785
Query: 359 PAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADP----EDGKPVM 414
+PV E V P K + +DA +A + KKE E+ KP
Sbjct: 786 KSPVKEEV------------KSPEKAKSPLKEDA-KAPEKEIPKKEEVKSPVKEEEKPQE 832
Query: 415 DKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDAL 474
KVKE K+ + EK P + EE KD K PK KE P E+ A+
Sbjct: 833 VKVKEPPKKAEEEKA-------PATPKTEEKKDSK-KEEAPK--KEAPKPKVEEKKEPAV 882
Query: 475 SEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLS 534
+ A + ED K E + + P T + K+ DDA K
Sbjct: 883 EKPKESKVEAKKEEAEDKKKVPT-PEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP 941
Query: 535 DSLGQRQPDPDENKPM--------EDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQ 586
+++ E K E+K K +AKA+ DK ++ + P + +
Sbjct: 942 SKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTD 1001
Query: 587 DKPVKPPTKKSED 599
K KPP K +ED
Sbjct: 1002 QKDSKPPEKATED 1014
Score = 76.3 bits (186), Expect = 9e-14
Identities = 116/486 (23%), Positives = 194/486 (39%), Gaps = 45/486 (9%)
Query: 2 NPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTK 61
+P E K+ + E K K P++A +A + ++S E++ ++ E K+
Sbjct: 526 SPAEAKSPEKEEAKSPAEVKS---PEKAKSPAKEEAKSPPE-AKSPEKEEAKSPAEVKSP 581
Query: 62 PQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAV---PVESKPDKPSGKSGMDAALDD 118
+ A E+ + A S + ++++ +PA PV+ + P+ + A
Sbjct: 582 EKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSP 641
Query: 119 LIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKK----EGI 174
+ PE+ + PE + S + K E P K + + + E
Sbjct: 642 TKEEAKSPEKAKS-------PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 175 TGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQ 234
P + +K P+ A + + SP A K KEE+ KA+S V+ A
Sbjct: 695 KSPVKEEAK--SPEKAKSPVKEE--AKSPEKA-KSPVKEEAKTPEKAKSP--VKEEAKSP 747
Query: 235 EKKRKVEK----DTMSDQA-LEALSASLGTRQAEPELDLRSIKEVDEA--KAKEEKLEKC 287
EK + EK D S +A A + PE +KE ++ KAK E
Sbjct: 748 EKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDA 807
Query: 288 GEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESEL-IDELSEDFDRSECKEKPSK 346
++ IP + +K ++ KP + +E PK E + +E+ S+ +E P K
Sbjct: 808 KAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKK 867
Query: 347 --PTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKE 404
P K EE K A E S A E A K VP EA A K++
Sbjct: 868 EAPKPKVEEKKEPAVEKPKE--------SKVEAKKEEAEDKKKVPTPEKEAPAKVEVKED 919
Query: 405 ADPEDGKPVMDKVKEKAKEEDREKLGEKEETIP--PDYRLEEVKDKDGKPLLPKESKEQL 462
A P++ V K + AK ++ K EK+E P D + E+ K + KP ++KE
Sbjct: 920 AKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDD 979
Query: 463 PPMSED 468
+S++
Sbjct: 980 KTLSKE 985
Score = 74.7 bits (182), Expect = 3e-13
Identities = 106/475 (22%), Positives = 177/475 (37%), Gaps = 36/475 (7%)
Query: 2 NPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTK 61
+P + +A K+ PE KS + P + + K+ AE + EK+ P
Sbjct: 552 SPAKEEA-KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPV-- 608
Query: 62 PQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLID 121
++ + E+ + + + P + K +K+ +P P+K +A +
Sbjct: 609 -KEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAK 667
Query: 122 TLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPK----YRELLAKKEGITGP 177
+ E E P ++ S + K E P K +E E P
Sbjct: 668 SPVKAEAKSPEKAK--SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725
Query: 178 PADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEV----LKAQSAGTVRSAAP- 232
+ +K P+ A + + SP A K EK ++ +V K + RS A
Sbjct: 726 VKEEAKT--PEKAKSPVKEE--AKSPEKA-KSPEKAKTLDVKSPEAKTPAKEEARSPADK 780
Query: 233 -PQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDD 291
P++ K V+++ S E + L PE ++ +EV +EEK ++ +
Sbjct: 781 FPEKAKSPVKEEVKSP---EKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKE 837
Query: 292 ETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKT 351
+E PAT K + + EE PK + ++E E K K SK K
Sbjct: 838 PPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE---KPKESKVEAKK 894
Query: 352 EES--KAAAPAPVSEAVCRTSMCS-------IQSAPPEPATLKGTVPDDAVEALADSLGK 402
EE+ K P P EA + + + A EP K P E + K
Sbjct: 895 EEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEK 954
Query: 403 KEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKE 457
K+ E K +K K +AK ++ +K KE + P + E+ D K P E
Sbjct: 955 KDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPE 1009
Score = 59.7 bits (143), Expect = 8e-09
Identities = 86/378 (22%), Positives = 146/378 (38%), Gaps = 38/378 (10%)
Query: 7 KAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMI 66
KA E E+ K KS K + + KA ++S E+ S E K+ +
Sbjct: 651 KAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKS 710
Query: 67 SAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDA-ALDDLIDTLGG 125
E+ + A S + K +K+ +P P+K KS A LD
Sbjct: 711 PVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK--AKSPEKAKTLDVKSPEAKT 768
Query: 126 PEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLA------KKEGITGPPA 179
P + E + PE + S EE+ E P + A KKE + P
Sbjct: 769 PAKEEARSPADKFPEKA---KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVK 825
Query: 180 DSSKP--IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKK 237
+ KP + + + +P KK K+E +A P EK
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKP 885
Query: 238 RKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSE 297
++ + + ++A + ++A +++++ ++AK KE K E ++ + ++
Sbjct: 886 KESKVEAKKEEAEDKKKVPTPEKEAPAKVEVK-----EDAKPKE-KTEVAKKEPDDAKAK 939
Query: 298 YRLKPATDKDGKP--------LLPEPEEKPKPRSESELIDE-LSEDFDR---------SE 339
KPA K+ P +PEEKPK ++++ D+ LS++ + S
Sbjct: 940 EPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSS 999
Query: 340 CKEKPSKPTEKTEESKAA 357
+K SKP EK E KAA
Sbjct: 1000 TDQKDSKPPEKATEDKAA 1017
Score = 47.8 bits (112), Expect = 3e-05
Identities = 59/270 (21%), Positives = 103/270 (38%), Gaps = 46/270 (17%)
Query: 409 DGKPVMDKVKE--KAKEEDREKLGEK--------EETIPPDYRLEEVKDKDGKPLLPKES 458
+G P + V K K E++ K+ EK EE EEV +++ K +E
Sbjct: 424 EGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEG 483
Query: 459 KEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD 518
KE+ E E G + S E+A + +A +P ++
Sbjct: 484 KEEEGGEEE--------EAEGGEEETKSPPAEEAA-------------SPEKEAKSPVKE 522
Query: 519 TSQSDKDLDDALDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLGERDDTIPPEY 577
++S + + P+ +E K P E K EKAK+ +++ + PE
Sbjct: 523 EAKSPAEA-------------KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEK 569
Query: 578 RHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKK 637
P K + E++K PA+ + P A S + S E +++ K++ K
Sbjct: 570 EEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE-AKSPVKEEAKS 628
Query: 638 AASSSKAPKNGGKAKDSAKTTEETSKPKDD 667
A K K+ AK+ E+ P+ +
Sbjct: 629 PAEVKSPEKAKSPTKEEAKSPEKAKSPEKE 658
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 67.0 bits (162), Expect = 5e-11
Identities = 101/401 (25%), Positives = 155/401 (38%), Gaps = 65/401 (16%)
Query: 205 AAGKKTEKEESTEVLKAQSAGTVRSAAPP-------------QEKKRKVEKDTMSDQALE 251
AA +K E+ E+ E A V++ AP QE++ + ++ SDQA E
Sbjct: 491 AAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE 550
Query: 252 ALSASLGT------RQAEPELDLRSIKEVDEAK---AKEEKLEKCGEDDETIPSEYRLKP 302
S G+ Q E E + + E EAK EEK E+ +E + KP
Sbjct: 551 GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP 610
Query: 303 ATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTE-ESKAAAPAP 361
K P P E+ P +S + ++ +S +EK P K+ E K +P
Sbjct: 611 EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV- 669
Query: 362 VSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALAD--SLGKKEADPEDGKPVMDKVKE 419
S P K VP VE +GK E E+ K +VKE
Sbjct: 670 --------------SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK----EVKE 711
Query: 420 KAKEEDREKLGEKEETIPPDYRLEE-VKD----------KDGKPLLPKESKEQLPPMSED 468
KEE EK EK + +P + E VK+ K K L KE+KE+ P+ ++
Sbjct: 712 APKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQE 771
Query: 469 FLLDAL-----SEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSD 523
+ SE+ + A + ED + + E + T + G+ +
Sbjct: 772 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEV-EGKEEVEQETKEKGS---GREEEK 827
Query: 524 KDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRD 564
+ + LD LS + ++ D E K + K EK +E D
Sbjct: 828 GVVTNGLD-LSPADEKKGGDKSEEKVVVTKTVEKITSEGGD 867
Score = 48.5 bits (114), Expect = 2e-05
Identities = 89/391 (22%), Positives = 138/391 (35%), Gaps = 52/391 (13%)
Query: 192 DALSSDFTCGSPTAAGKKTEKEESTE--VLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQA 249
D L+ AA +K + E T G + + PP K++K +
Sbjct: 386 DLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPK 445
Query: 250 LEAL---------SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 300
L+ + ++E E L +I E KEEK E E +E +E
Sbjct: 446 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEE 505
Query: 301 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEK---------- 350
A K PE +E+ + E E +E E+ + ++ + +EK
Sbjct: 506 VAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGE 565
Query: 351 TEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDG 410
EE + A A EA + ++ E AT + V D VE +K P
Sbjct: 566 QEEGETEAEAEGEEAEAKEEK-KVEEKSEEVATKEELVADAKVEK-----PEKAKSPVPK 619
Query: 411 KPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFL 470
PV +K K + E EK ++ P +EE K K P P E K + P
Sbjct: 620 SPVEEKGKSPVPKSPVE---EKGKSPVPKSPVEE-KGKSPVPKSPVEEKGKSPVSK---- 671
Query: 471 LDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDAL 530
+ E P S + E+AK A + + Q + P++ K+
Sbjct: 672 -SPVEEKAKSPVPKSPV--EEAKSKAEVGK-GEQKEEEEKEVKEAPKEEKVEKKE----- 722
Query: 531 DKLSDSLGQRQPDPDENKPMEDKVKEKAKAE 561
++ D E K E VKE+A AE
Sbjct: 723 --------EKPKDVPEKKKAESPVKEEAVAE 745
Score = 30.8 bits (68), Expect = 4.2
Identities = 58/296 (19%), Positives = 110/296 (37%), Gaps = 36/296 (12%)
Query: 12 EPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTK---------- 61
E E +++ + ++ ++ + S + K+ + A+ + EK+ P K
Sbjct: 570 ETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSP 629
Query: 62 -PQDMISAGGESVAGITAISGK-----PGDKKKEK-KSLTPAVPVESKPDKPSGKSGMDA 114
P+ + G+S + + K P +EK KS PVE K P KS ++
Sbjct: 630 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEE 689
Query: 115 ALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGI 174
A +G E+ EEE EV + +E+ ++ +P K + KE
Sbjct: 690 AKSKA--EVGKGEQKEEEE-----KEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEA 742
Query: 175 TGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQ 234
+K + + G P K EKE++ ++ G+ + A +
Sbjct: 743 VAEVVTITKSV----KVHLEKETKEEGKPLQQEK--EKEKAGGEGGSEEEGSDKGAKGSR 796
Query: 235 EKKRKVEKDTMSDQALEALSASLGTRQAEPE------LDLRSIKEVDEAKAKEEKL 284
++ V + + +E + G+ + E + LDL E EEK+
Sbjct: 797 KEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKV 852
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 67.0 bits (162), Expect = 5e-11
Identities = 101/401 (25%), Positives = 155/401 (38%), Gaps = 65/401 (16%)
Query: 205 AAGKKTEKEESTEVLKAQSAGTVRSAAPP-------------QEKKRKVEKDTMSDQALE 251
AA +K E+ E+ E A V++ AP QE++ + ++ SDQA E
Sbjct: 115 AAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE 174
Query: 252 ALSASLGT------RQAEPELDLRSIKEVDEAK---AKEEKLEKCGEDDETIPSEYRLKP 302
S G+ Q E E + + E EAK EEK E+ +E + KP
Sbjct: 175 GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP 234
Query: 303 ATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTE-ESKAAAPAP 361
K P P E+ P +S + ++ +S +EK P K+ E K +P
Sbjct: 235 EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV- 293
Query: 362 VSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALAD--SLGKKEADPEDGKPVMDKVKE 419
S P K VP VE +GK E E+ K +VKE
Sbjct: 294 --------------SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK----EVKE 335
Query: 420 KAKEEDREKLGEKEETIPPDYRLEE-VKD----------KDGKPLLPKESKEQLPPMSED 468
KEE EK EK + +P + E VK+ K K L KE+KE+ P+ ++
Sbjct: 336 APKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQE 395
Query: 469 FLLDAL-----SEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSD 523
+ SE+ + A + ED + + E + T + G+ +
Sbjct: 396 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEV-EGKEEVEQETKEKGS---GREEEK 451
Query: 524 KDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRD 564
+ + LD LS + ++ D E K + K EK +E D
Sbjct: 452 GVVTNGLD-LSPADEKKGGDKSEEKVVVTKTVEKITSEGGD 491
Score = 48.5 bits (114), Expect = 2e-05
Identities = 89/391 (22%), Positives = 138/391 (35%), Gaps = 52/391 (13%)
Query: 192 DALSSDFTCGSPTAAGKKTEKEESTE--VLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQA 249
D L+ AA +K + E T G + + PP K++K +
Sbjct: 10 DLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPK 69
Query: 250 LEAL---------SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 300
L+ + ++E E L +I E KEEK E E +E +E
Sbjct: 70 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEE 129
Query: 301 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEK---------- 350
A K PE +E+ + E E +E E+ + ++ + +EK
Sbjct: 130 VAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGE 189
Query: 351 TEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDG 410
EE + A A EA + ++ E AT + V D VE +K P
Sbjct: 190 QEEGETEAEAEGEEAEAKEEK-KVEEKSEEVATKEELVADAKVEK-----PEKAKSPVPK 243
Query: 411 KPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFL 470
PV +K K + E EK ++ P +EE K K P P E K + P
Sbjct: 244 SPVEEKGKSPVPKSPVE---EKGKSPVPKSPVEE-KGKSPVPKSPVEEKGKSPVSK---- 295
Query: 471 LDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDAL 530
+ E P S + E+AK A + + Q + P++ K+
Sbjct: 296 -SPVEEKAKSPVPKSPV--EEAKSKAEVGK-GEQKEEEEKEVKEAPKEEKVEKKE----- 346
Query: 531 DKLSDSLGQRQPDPDENKPMEDKVKEKAKAE 561
++ D E K E VKE+A AE
Sbjct: 347 --------EKPKDVPEKKKAESPVKEEAVAE 369
Score = 30.8 bits (68), Expect = 4.2
Identities = 58/296 (19%), Positives = 110/296 (37%), Gaps = 36/296 (12%)
Query: 12 EPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTK---------- 61
E E +++ + ++ ++ + S + K+ + A+ + EK+ P K
Sbjct: 194 ETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSP 253
Query: 62 -PQDMISAGGESVAGITAISGK-----PGDKKKEK-KSLTPAVPVESKPDKPSGKSGMDA 114
P+ + G+S + + K P +EK KS PVE K P KS ++
Sbjct: 254 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEE 313
Query: 115 ALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGI 174
A +G E+ EEE EV + +E+ ++ +P K + KE
Sbjct: 314 AKSKA--EVGKGEQKEEEE-----KEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEA 366
Query: 175 TGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQ 234
+K + + G P K EKE++ ++ G+ + A +
Sbjct: 367 VAEVVTITKSV----KVHLEKETKEEGKPLQQEK--EKEKAGGEGGSEEEGSDKGAKGSR 420
Query: 235 EKKRKVEKDTMSDQALEALSASLGTRQAEPE------LDLRSIKEVDEAKAKEEKL 284
++ V + + +E + G+ + E + LDL E EEK+
Sbjct: 421 KEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKV 476
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 63.9 bits (154), Expect = 4e-10
Identities = 167/753 (22%), Positives = 265/753 (35%), Gaps = 127/753 (16%)
Query: 3 PTETKAVKTEPEKKSQSTKPKSLPKQASDT----GSNDAHNKKAVSRSAEQQPSEKSTEP 58
P + +V +E +K + PK T S+ A K + S Q +E+ T P
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
Query: 59 -----KTKPQDMISAGGESVAGIT--AISGKPGDKK--------KEKKSLTPAVPVESKP 103
KP GE V+ AI D K E K PV+ K
Sbjct: 794 PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE 853
Query: 104 DKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPK 163
+ ++ M D G P T G V P S +E +R
Sbjct: 854 EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA--GQTVPTPQQSPKPQEQSRR------- 904
Query: 164 YRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQS 223
IT P S+P P + + F G + S + A
Sbjct: 905 ---FSLNLGSITDAP--KSQPTTPQETVTGKLFGF--------GASIFSQASNLISTAGQ 951
Query: 224 AGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE-E 282
G + P K+ Q + T QA P +SI E KA E
Sbjct: 952 PGPHSQSGPGAPMKQA----PAPSQPPTSQGPPKSTGQAPPA-PAKSIPVKKETKAPAAE 1006
Query: 283 KLEKCGEDDETIP-SEYRLKPATDKDGKPLLPEP---------EEKPKPRSESELI-DEL 331
KLE E T+ +E KP KD K L EP E+ PKP S L EL
Sbjct: 1007 KLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTEL 1066
Query: 332 S------EDFDR-SECKEKPS-----KPT-EKTEESKAAAPAPVSEAVCRTSMCSIQSAP 378
+ +F+ +ECK + PT TE + ++ + I+ P
Sbjct: 1067 NIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP 1126
Query: 379 PEPATLKGT---VPDD------AVEALADSLGKKEAD--PEDGKPVMDKVKEKAK----- 422
P P+ K + VP + AV + K+E + E K +++KVKE
Sbjct: 1127 PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIP 1186
Query: 423 --------------EEDREKLGEKEETIPPDYRL----EEVKDKDGKPLLPKESKEQLPP 464
E+D+ ++++ +P + +L E+++ ++ KPLL +E+ P
Sbjct: 1187 PMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLL----EEKKPT 1242
Query: 465 MSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD-----T 519
+ LL Q LK +++ A ++ + T Q G P+
Sbjct: 1243 PEDKKLLPEAKTSAPEEQKHDLLK---SQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLP 1299
Query: 520 SQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKE-KAKAEHRDKLGERDDTIPPEYR 578
S + + L DK + ++ ++ P KP D+V+ K K E D + + P+
Sbjct: 1300 SGTPQSLPKEDDKTTKTIKEQPQPPCTAKP--DQVEPGKEKTEKEDDKSDTSSSQQPKSP 1357
Query: 579 HLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK-- 636
L D G + S P D++D + L D S S+ + + AK +
Sbjct: 1358 QGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVL 1417
Query: 637 ---KAASSSKAPKNGGKAKDSAKTTEETSKPKD 666
+A +S+ A + K + + E +PKD
Sbjct: 1418 SILEAQASTLADEKSEKKTQPHEVSPE--QPKD 1448
Score = 46.6 bits (109), Expect = 7e-05
Identities = 125/616 (20%), Positives = 219/616 (35%), Gaps = 57/616 (9%)
Query: 3 PTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKP 62
P +T A +T P K + P + + ++ QQP ST+P +
Sbjct: 456 PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG--STKPPPQQ 513
Query: 63 QDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDT 122
+ S +PG K + +PA P + KP ++G L
Sbjct: 514 PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP---- 569
Query: 123 LGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSS 182
+ ++ + P+ P+ +T + + +P K + T S
Sbjct: 570 -PTVSPSAKQPPSQGLPKTICPLCNT-----TELLLHVPEKANFNTCTECQTT---VCSL 620
Query: 183 KPIGPDDAIDALSS--DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAA----PPQEK 236
P+ + + C A G S+ K ++A ++A PQ +
Sbjct: 621 CGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ 680
Query: 237 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE----EKLEKCGEDDE 292
+ +KD Q LS + ++ P + ++ AKAK+ + L K E
Sbjct: 681 QTSPKKDAAPKQ---DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKE 737
Query: 293 -TIPSEYRLKP-ATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEK 350
++PSE P A DK +P + +P S + ++ +S+ +EK + P +
Sbjct: 738 PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKT 797
Query: 351 TEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDG 410
+ + P E V A P PA+ + ++S G+K+ DP
Sbjct: 798 DSAKPSQSFPPTGEKVSPFD----SKAIPRPASDSKIISHPGPS--SESKGQKQVDPVQK 851
Query: 411 KPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPK-ESKEQLPPMSEDF 469
K K + K + K K PP R + PK + + + ++
Sbjct: 852 KEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGS 911
Query: 470 LLDALSEDFSGPQNASSLKF--EDAKLAAAISEVVSQT----PASTTQAGAPPRDT-SQS 522
+ DA + PQ + K A + + S ++S P S + GAP + + S
Sbjct: 912 ITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPS 971
Query: 523 DKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLD 582
K S GQ P P ++ P VK++ KA +KL + + P R
Sbjct: 972 QPPTSQGPPK---STGQAPPAPAKSIP----VKKETKAPAAEKLEPKAEQAPTVKR---- 1020
Query: 583 DNGQDKPVKPPTKKSE 598
+ KP PP K S+
Sbjct: 1021 TETEKKP--PPIKDSK 1034
Score = 42.0 bits (97), Expect = 0.002
Identities = 135/667 (20%), Positives = 244/667 (36%), Gaps = 134/667 (20%)
Query: 5 ETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQD 64
+T+A K EK ++ + +P + + + SA Q+ E K P++
Sbjct: 1165 KTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEE 1224
Query: 65 MISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTL- 123
E + P DKK ++ T A P E K D KS + A + L +
Sbjct: 1225 EKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSA-PEEQKHDLL--KSQVQIAEEKLEGRVA 1281
Query: 124 ------GGPEETEEEN----TTYTGPEVSDPMSSTYIEE-----LGKREVTIPPKYRELL 168
G +T+ E T + P+ D + T E+ K + P K +
Sbjct: 1282 PKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEK--- 1338
Query: 169 AKKEGITGPPADSSKPIGPDDAIDA-LSSDFTCGSPTAAGK-----KTEKEESTEVLKAQ 222
+KE + S +P P D SSD G ++ G+ T++++ + LK
Sbjct: 1339 TEKEDDKSDTSSSQQPKSPQGLSDTGYSSD---GISSSLGEIPSLIPTDEKDILKGLKKD 1395
Query: 223 SAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSI-----KEVDEA 277
S S + P + K+E +S LEA +++L ++E + + K+ ++
Sbjct: 1396 SFSQESSPSSPSDLA-KLESTVLS--ILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKT 1452
Query: 278 KAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR 337
++ E LE ++E S+ K KD + +P ++ + +SE +D+++
Sbjct: 1453 QSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDH---KEKSEFVDDITTR--- 1506
Query: 338 SECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALA 397
+P + EES + +PV + RTS+ S S
Sbjct: 1507 -------REPYDSVEESSESENSPVPQRKRRTSVGSSSS--------------------- 1538
Query: 398 DSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKE 457
++ K+ED + GE+E+ I +E D+D
Sbjct: 1539 ---------------------DEYKQEDSQGSGEEEDFIRKQI-IEMSADEDAS------ 1570
Query: 458 SKEQLPPMSEDFLLDALSEDFSGPQNASSLKFE-DAKLAAAISEVVSQTPASTTQAGAPP 516
++F+ + L E S ++ + + K+ A +++ +++ A
Sbjct: 1571 -----GSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGR 1625
Query: 517 RDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPE 576
R S D+D D+A D+ S L R+ E+ E+ V R K E + TI +
Sbjct: 1626 RH-SWHDED-DEAFDE-SPELKYRETKSQES---EELVVTGGGGLRRFKTIELNSTIADK 1679
Query: 577 Y--------RHLLDDNGQDKPVKPPTKKSEDSKK-------------PADDQDPIDALSG 615
Y L D + ++ T ED + P + +L
Sbjct: 1680 YSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDE 1739
Query: 616 DLDSCPS 622
D DS PS
Sbjct: 1740 DSDSSPS 1746
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 63.9 bits (154), Expect = 4e-10
Identities = 167/753 (22%), Positives = 265/753 (35%), Gaps = 127/753 (16%)
Query: 3 PTETKAVKTEPEKKSQSTKPKSLPKQASDT----GSNDAHNKKAVSRSAEQQPSEKSTEP 58
P + +V +E +K + PK T S+ A K + S Q +E+ T P
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
Query: 59 -----KTKPQDMISAGGESVAGIT--AISGKPGDKK--------KEKKSLTPAVPVESKP 103
KP GE V+ AI D K E K PV+ K
Sbjct: 794 PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE 853
Query: 104 DKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPK 163
+ ++ M D G P T G V P S +E +R
Sbjct: 854 EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA--GQTVPTPQQSPKPQEQSRR------- 904
Query: 164 YRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQS 223
IT P S+P P + + F G + S + A
Sbjct: 905 ---FSLNLGSITDAP--KSQPTTPQETVTGKLFGF--------GASIFSQASNLISTAGQ 951
Query: 224 AGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE-E 282
G + P K+ Q + T QA P +SI E KA E
Sbjct: 952 PGPHSQSGPGAPMKQA----PAPSQPPTSQGPPKSTGQAPPA-PAKSIPVKKETKAPAAE 1006
Query: 283 KLEKCGEDDETIP-SEYRLKPATDKDGKPLLPEP---------EEKPKPRSESELI-DEL 331
KLE E T+ +E KP KD K L EP E+ PKP S L EL
Sbjct: 1007 KLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTEL 1066
Query: 332 S------EDFDR-SECKEKPS-----KPT-EKTEESKAAAPAPVSEAVCRTSMCSIQSAP 378
+ +F+ +ECK + PT TE + ++ + I+ P
Sbjct: 1067 NIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP 1126
Query: 379 PEPATLKGT---VPDD------AVEALADSLGKKEAD--PEDGKPVMDKVKEKAK----- 422
P P+ K + VP + AV + K+E + E K +++KVKE
Sbjct: 1127 PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIP 1186
Query: 423 --------------EEDREKLGEKEETIPPDYRL----EEVKDKDGKPLLPKESKEQLPP 464
E+D+ ++++ +P + +L E+++ ++ KPLL +E+ P
Sbjct: 1187 PMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLL----EEKKPT 1242
Query: 465 MSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD-----T 519
+ LL Q LK +++ A ++ + T Q G P+
Sbjct: 1243 PEDKKLLPEAKTSAPEEQKHDLLK---SQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLP 1299
Query: 520 SQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKE-KAKAEHRDKLGERDDTIPPEYR 578
S + + L DK + ++ ++ P KP D+V+ K K E D + + P+
Sbjct: 1300 SGTPQSLPKEDDKTTKTIKEQPQPPCTAKP--DQVEPGKEKTEKEDDKSDTSSSQQPKSP 1357
Query: 579 HLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK-- 636
L D G + S P D++D + L D S S+ + + AK +
Sbjct: 1358 QGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVL 1417
Query: 637 ---KAASSSKAPKNGGKAKDSAKTTEETSKPKD 666
+A +S+ A + K + + E +PKD
Sbjct: 1418 SILEAQASTLADEKSEKKTQPHEVSPE--QPKD 1448
Score = 46.6 bits (109), Expect = 7e-05
Identities = 125/616 (20%), Positives = 219/616 (35%), Gaps = 57/616 (9%)
Query: 3 PTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKP 62
P +T A +T P K + P + + ++ QQP ST+P +
Sbjct: 456 PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG--STKPPPQQ 513
Query: 63 QDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDT 122
+ S +PG K + +PA P + KP ++G L
Sbjct: 514 PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP---- 569
Query: 123 LGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSS 182
+ ++ + P+ P+ +T + + +P K + T S
Sbjct: 570 -PTVSPSAKQPPSQGLPKTICPLCNT-----TELLLHVPEKANFNTCTECQTT---VCSL 620
Query: 183 KPIGPDDAIDALSS--DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAA----PPQEK 236
P+ + + C A G S+ K ++A ++A PQ +
Sbjct: 621 CGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ 680
Query: 237 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE----EKLEKCGEDDE 292
+ +KD Q LS + ++ P + ++ AKAK+ + L K E
Sbjct: 681 QTSPKKDAAPKQ---DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKE 737
Query: 293 -TIPSEYRLKP-ATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEK 350
++PSE P A DK +P + +P S + ++ +S+ +EK + P +
Sbjct: 738 PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKT 797
Query: 351 TEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDG 410
+ + P E V A P PA+ + ++S G+K+ DP
Sbjct: 798 DSAKPSQSFPPTGEKVSPFD----SKAIPRPASDSKIISHPGPS--SESKGQKQVDPVQK 851
Query: 411 KPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPK-ESKEQLPPMSEDF 469
K K + K + K K PP R + PK + + + ++
Sbjct: 852 KEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGS 911
Query: 470 LLDALSEDFSGPQNASSLKF--EDAKLAAAISEVVSQT----PASTTQAGAPPRDT-SQS 522
+ DA + PQ + K A + + S ++S P S + GAP + + S
Sbjct: 912 ITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPS 971
Query: 523 DKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLD 582
K S GQ P P ++ P VK++ KA +KL + + P R
Sbjct: 972 QPPTSQGPPK---STGQAPPAPAKSIP----VKKETKAPAAEKLEPKAEQAPTVKR---- 1020
Query: 583 DNGQDKPVKPPTKKSE 598
+ KP PP K S+
Sbjct: 1021 TETEKKP--PPIKDSK 1034
Score = 42.0 bits (97), Expect = 0.002
Identities = 135/667 (20%), Positives = 244/667 (36%), Gaps = 134/667 (20%)
Query: 5 ETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQD 64
+T+A K EK ++ + +P + + + SA Q+ E K P++
Sbjct: 1165 KTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEE 1224
Query: 65 MISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTL- 123
E + P DKK ++ T A P E K D KS + A + L +
Sbjct: 1225 EKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSA-PEEQKHDLL--KSQVQIAEEKLEGRVA 1281
Query: 124 ------GGPEETEEEN----TTYTGPEVSDPMSSTYIEE-----LGKREVTIPPKYRELL 168
G +T+ E T + P+ D + T E+ K + P K +
Sbjct: 1282 PKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEK--- 1338
Query: 169 AKKEGITGPPADSSKPIGPDDAIDA-LSSDFTCGSPTAAGK-----KTEKEESTEVLKAQ 222
+KE + S +P P D SSD G ++ G+ T++++ + LK
Sbjct: 1339 TEKEDDKSDTSSSQQPKSPQGLSDTGYSSD---GISSSLGEIPSLIPTDEKDILKGLKKD 1395
Query: 223 SAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSI-----KEVDEA 277
S S + P + K+E +S LEA +++L ++E + + K+ ++
Sbjct: 1396 SFSQESSPSSPSDLA-KLESTVLS--ILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKT 1452
Query: 278 KAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR 337
++ E LE ++E S+ K KD + +P ++ + +SE +D+++
Sbjct: 1453 QSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDH---KEKSEFVDDITTR--- 1506
Query: 338 SECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALA 397
+P + EES + +PV + RTS+ S S
Sbjct: 1507 -------REPYDSVEESSESENSPVPQRKRRTSVGSSSS--------------------- 1538
Query: 398 DSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKE 457
++ K+ED + GE+E+ I +E D+D
Sbjct: 1539 ---------------------DEYKQEDSQGSGEEEDFIRKQI-IEMSADEDAS------ 1570
Query: 458 SKEQLPPMSEDFLLDALSEDFSGPQNASSLKFE-DAKLAAAISEVVSQTPASTTQAGAPP 516
++F+ + L E S ++ + + K+ A +++ +++ A
Sbjct: 1571 -----GSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGR 1625
Query: 517 RDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPE 576
R S D+D D+A D+ S L R+ E+ E+ V R K E + TI +
Sbjct: 1626 RH-SWHDED-DEAFDE-SPELKYRETKSQES---EELVVTGGGGLRRFKTIELNSTIADK 1679
Query: 577 Y--------RHLLDDNGQDKPVKPPTKKSEDSKK-------------PADDQDPIDALSG 615
Y L D + ++ T ED + P + +L
Sbjct: 1680 YSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDE 1739
Query: 616 DLDSCPS 622
D DS PS
Sbjct: 1740 DSDSSPS 1746
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 61.6 bits (148), Expect = 2e-09
Identities = 122/627 (19%), Positives = 229/627 (36%), Gaps = 105/627 (16%)
Query: 10 KTEPEKKSQSTKPKSLPKQASDTGSNDAHNK-KAVSRSAEQQPSEKSTEPKTKP---QDM 65
KTE ++K + + + + G K K ++ ++ EK +P+TK +
Sbjct: 147 KTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQK 206
Query: 66 ISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGG 125
+ E T K G ++K K++ V+ P KP
Sbjct: 207 KAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPK------------------ 248
Query: 126 PEETEEENTTYTGPEVSDPMS-STYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKP 184
E+ ++E + E D + Y+ ++ + +L + PP + +
Sbjct: 249 -EKEDKEKAAVSKHEQKDQYAFCRYMIDIFV--------HGDLKPGQSPAIPPPLPTEQA 299
Query: 185 IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDT 244
P A AL KK EK+ ++E K + ++ K+K EK+T
Sbjct: 300 SRPTPASPALEEK------EGEKKKAEKKVTSETKKKEK----------EDIKKKSEKET 343
Query: 245 MSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPAT 304
D + + T+Q ++ ++ + DE K +K +K P+E
Sbjct: 344 AIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKK--------PAEVEQPKGK 395
Query: 305 DKDGKPLLPEPEEKPKPRSESELIDELSEDFDRS-ECKEKPSKPTEKTEESKAAAPAPVS 363
++ K EP + PK E S D+ + K + +K K A P
Sbjct: 396 KQEKKEKHVEPAKSPK--------KEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKE 447
Query: 364 EAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKE 423
E +T I+ K ++ GK+E P K +K E K+
Sbjct: 448 EKTTKTVEQEIRKE-------KSGKTSSILKDKEPIKGKEEKVPASLK---EKEPETKKD 497
Query: 424 EDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQN 483
E K G++ + PP +L+ K++ +P + KE+K P +SE + +D P+
Sbjct: 498 EKMSKAGKEVKPKPP--QLQGKKEEKPEPQIKKEAK---PAISEKVQIH--KQDIVKPEK 550
Query: 484 ASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPD 543
S + K V+ Q A T + A P+ T +++ ++ S+ +P
Sbjct: 551 TVSHGKPEEK-------VLKQVKAVTIEKTAKPKPTKKAEH-----REREPPSIKTDKPK 598
Query: 544 PDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKP 603
P E K K E + E++ + +HL ++ + ++KP
Sbjct: 599 PTPKGTSEVTESGKKKTE----ISEKESKEKADMKHLREEKVSTRKESLQLHNVTKAEKP 654
Query: 604 ADDQDPIDALSGDLDSCPSTTETSQNT 630
A +S D++ P++ + + T
Sbjct: 655 A-------RVSKDVEDVPASKKAKEGT 674
Score = 40.4 bits (93), Expect = 0.005
Identities = 64/270 (23%), Positives = 103/270 (38%), Gaps = 36/270 (13%)
Query: 7 KAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQP-SEKSTEPKTKPQDM 65
KAV + E+K+ T + + K+ S S+ +K+ + E+ P S K EP+TK +
Sbjct: 440 KAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEK 499
Query: 66 ISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGG 125
+S G+ V KP + + K P K KP+ + D++
Sbjct: 500 MSKAGKEV--------KPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVK---- 547
Query: 126 PEETEEENTTYTGPE--VSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPA---D 180
PE+T ++ PE V + + IE+ K + T ++RE PP+ D
Sbjct: 548 PEKT----VSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHRE--------REPPSIKTD 595
Query: 181 SSKPI--GPDDAIDALSSDFTCG---SPTAAGKKTEKEESTEVLK-AQSAGTVRSAAPPQ 234
KP G + ++ S A K +EE K + V A P
Sbjct: 596 KPKPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPA 655
Query: 235 EKKRKVEKDTMSDQALEALSASLGTRQAEP 264
+ VE S +A E T+Q P
Sbjct: 656 RVSKDVEDVPASKKAKEGTEDVSPTKQKSP 685
Score = 38.5 bits (88), Expect = 0.020
Identities = 73/352 (20%), Positives = 131/352 (37%), Gaps = 42/352 (11%)
Query: 323 SESELIDELSEDFDRSECKEKPSKPTE----KTEESKAAAPAPVSEAVCRTSMCSIQSAP 378
SE E D+ ED D+ E E P + E KTE+ + ++ + +
Sbjct: 116 SEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVR 175
Query: 379 PEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 438
+ K + +E K A + +K +EK K+E K G++E+
Sbjct: 176 EKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKE--VKGGKQEKVKQT 233
Query: 439 DYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAI 498
+++EV+ KP KE KE+ A+S+ Q A D + +
Sbjct: 234 AAKVKEVQKTPSKP-KEKEDKEKA----------AVSKHEQKDQYAFCRYMIDIFVHGDL 282
Query: 499 SEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKA 558
Q+PA PP T Q+ + S +L +++ E K E KV +
Sbjct: 283 KP--GQSPAI-----PPPLPTEQASRP-----TPASPALEEKE---GEKKKAEKKVTSET 327
Query: 559 KAEHRD---KLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSG 615
K + ++ K E++ I E + + G+ K T K D+ D+
Sbjct: 328 KKKEKEDIKKKSEKETAIDVEKK----EPGKASETKQGTVKIAAQAAAKKDEKKEDSKK- 382
Query: 616 DLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 667
P+ E + ++K +K +K+PK + +T + K++
Sbjct: 383 --TKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEE 432
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 61.2 bits (147), Expect = 3e-09
Identities = 148/702 (21%), Positives = 226/702 (32%), Gaps = 113/702 (16%)
Query: 3 PTETKAVKTEPEKKSQSTKPK---SLPKQASDTGSND---AHNKKAVSRSAEQQPSEKST 56
PT TK+ T P++ + +T + + PK+ + T + + K A + E P+
Sbjct: 249 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 308
Query: 57 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 116
T P++ + T +P KE TP P + P KP+ + + A
Sbjct: 309 PAPTTPKEPAPTTPKEPTPTT--PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA- 365
Query: 117 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG 176
P +E T T +P +T E + P +E
Sbjct: 366 ---------PTTPKEPAPTTT----KEPSPTTPKEPAPTTTKSAPTTTKE--------PA 404
Query: 177 PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 236
P S P P + + + +P T K+ + K + T + AP K
Sbjct: 405 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 464
Query: 237 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDE--AKAKEEKLEKCGEDDETI 294
K +A ++ P + E A E+L ++ T
Sbjct: 465 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 524
Query: 295 PSEYRLKPATDKDGKPLLPE------PEE-------KPKPRSESELIDELSEDFDRSECK 341
+ P T K P P+ P+E +P P + E + + K
Sbjct: 525 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 584
Query: 342 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 401
E P+ T K K AP E T C P P T KGT P E +
Sbjct: 585 E-PAPTTPKKPAPKELAPTTTKEPTSTT--CD----KPAPTTPKGTAPTTPKEPAPTT-- 635
Query: 402 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 461
KE P K ++ +K KE + P KP P KE
Sbjct: 636 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE--LAPTTTKGPTSTTSDKP-APTTPKET 692
Query: 462 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 521
P ++ P + K + +TP TT + P T +
Sbjct: 693 APTTPKE------------PAPTTPKK---------PAPTTPETPPPTTSEVSTPTTTKE 731
Query: 522 S---DKDLDDALDKLSDSLGQRQPDPDENKPMEDKV---------KEKAKAEHRDKLGER 569
K D++ +LS + P EN P E V K + +DK ER
Sbjct: 732 PTTIHKSPDESTPELS---AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 788
Query: 570 DDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQN 629
D PE K T+K+ +SK A + T+ T+Q+
Sbjct: 789 DLRTTPETTTAAPK--MTKETATTTEKTTESKITA-------------TTTQVTSTTTQD 833
Query: 630 TAKDKCKKAASSSKAPKNGGKAKDSAKT-----TEETSKPKD 666
T K +++ APK K T EET+KPKD
Sbjct: 834 TTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKD 875
Score = 55.5 bits (132), Expect = 2e-07
Identities = 134/679 (19%), Positives = 214/679 (31%), Gaps = 75/679 (11%)
Query: 4 TETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQ 63
T + T P++ + +T + P + ++SA P E + P T +
Sbjct: 212 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA--PTTTKE 269
Query: 64 DMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTL 123
+ E T +P + TP P + P KP+ + +
Sbjct: 270 PAPTTPKEPAPTTTK---EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE---------- 316
Query: 124 GGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSK 183
P T + T T P+ P + K PK KE PA
Sbjct: 317 --PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-----PA---- 365
Query: 184 PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKD 243
P P + + + + +P T K T + T + P+E K+
Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 425
Query: 244 ----TMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYR 299
T + A T EP + KE K+ E T P E
Sbjct: 426 PAPTTPKEPAPTTPKKPAPTTPKEPAPT--TPKEPAPTTTKKPAPTTPKEPAPTTPKE-- 481
Query: 300 LKPATDKDGKPLLPEP-----EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES 354
P T K P PE EKP P + EL E+ P+ P E +
Sbjct: 482 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE-------PTPTTPEEPAPTT 534
Query: 355 -KAAAPAPVSEAVCRTSMCSIQSAPPEPA--TLKGTVPDDAVEALADSLGKKEADPEDGK 411
KAAAP E T + P EPA T K T P + A + K+ A K
Sbjct: 535 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKK 593
Query: 412 PVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES-----KEQLPPMS 466
P ++ +E +K P K P PKE KE P
Sbjct: 594 PAPKELAPTTTKEPTSTTCDKPAPTTP---------KGTAPTTPKEPAPTTPKEPAPTTP 644
Query: 467 EDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDL 526
+ L E P + K +LA ++ + T + P + K+
Sbjct: 645 KGTAPTTLKE----PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 700
Query: 527 DDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQ 586
K P P ++ ++ H+ D++ P +
Sbjct: 701 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP----DESTPELSAEPTPKALE 756
Query: 587 DKPVKP--PTKKSEDSKKPADDQDPIDALSG-DLDSCPSTTETSQNTAKDKCKKAASSSK 643
+ P +P PT K+ + KP D + DL + P TT + K+ +++
Sbjct: 757 NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTE 816
Query: 644 APKNGGKAKDSAKTTEETS 662
+ + ++ TT++T+
Sbjct: 817 SKITATTTQVTSTTTQDTT 835
Score = 50.4 bits (119), Expect = 5e-06
Identities = 101/497 (20%), Positives = 164/497 (32%), Gaps = 36/497 (7%)
Query: 183 KPIGPDDAIDALSS-DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVE 241
KP D+A L + DF +P + + K ++ + R + PP K
Sbjct: 81 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 140
Query: 242 KDTMSDQA-LEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 300
T++ + +E + +Q + KE + + + +EK D S+
Sbjct: 141 SLTVNKETTVETKETTTTNKQTSTDG-----KEKTTSAKETQSIEKTSAKDLAPTSKVLA 195
Query: 301 KPATDKDGK---PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAA 357
KP + P L P+E P P + E ++ + K P+ P E + +
Sbjct: 196 KPTPKAETTTKGPALTTPKE-PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 254
Query: 358 APAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKV 417
AP E T+ + P EPA P A + K+ A KP
Sbjct: 255 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 314
Query: 418 KEKAKEEDREKL-GEKEETIPPDYRLEEVKDKDGKPLLPKE-----SKEQLPPMSEDFLL 471
KE A +E +E P K+ P PK+ KE P ++
Sbjct: 315 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 374
Query: 472 DALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAP--PRDTS-QSDKDLDD 528
E + + E A + ++ PA TT AP P++ S + K+
Sbjct: 375 TTTKEP------SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428
Query: 529 ALDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQD 587
K ++P P K P KE A + + T P E
Sbjct: 429 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK----KPAPTTPKEPAPTTPKETAP 484
Query: 588 KPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKN 647
K T + + P + P +L P+T E T ++ + AP
Sbjct: 485 TTPKKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNT 542
Query: 648 GGKAKDSAKTTEETSKP 664
K+ A TT + P
Sbjct: 543 ---PKEPAPTTPKEPAP 556
Score = 44.3 bits (103), Expect = 4e-04
Identities = 57/267 (21%), Positives = 93/267 (34%), Gaps = 15/267 (5%)
Query: 175 TGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQ 234
T P ++KPI P ++ S S T + T + + T Q++ +
Sbjct: 114 TSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA 173
Query: 235 EKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETI 294
++ + +EK + D A + + T +AE ++ E K E
Sbjct: 174 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 233
Query: 295 PSEYRLKPATDKDGKPL------------LPEPEEKPKPRSESELIDELSEDFDRSECKE 342
P+ + P T K+ P P ++P P + E +++ + K
Sbjct: 234 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 293
Query: 343 KPSKPTEKTEES-KAAAPAPVSEAVCRTSMCSIQSAPPEPA-TLKGTVPDDAVEALADSL 400
P+ P E + K AP E T + P EPA T K P E A +
Sbjct: 294 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-APTA 352
Query: 401 GKKEADPEDGKPVMDKVKEKAKEEDRE 427
KK A +P KE A +E
Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKE 379
Score = 32.0 bits (71), Expect = 1.9
Identities = 54/255 (21%), Positives = 93/255 (36%), Gaps = 21/255 (8%)
Query: 419 EKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDF 478
E+ +E D + +K + PDY + KD K K+ PP+ + E
Sbjct: 38 ERGRECDCDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPKPPV--------VDEAG 89
Query: 479 SGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDT--SQSDKDLDDALDKLSDS 536
SG N K + VS +P TT PR + SD + +L ++
Sbjct: 90 SGLDN-GDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 148
Query: 537 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT--IPPEYRHLLDDNGQ-DKPVKPP 593
+ + NK KEK + + E+ + P + L + + K P
Sbjct: 149 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP 208
Query: 594 TKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKC----KKAASSSKAPKNGG 649
+ P ++P A + + P+T +++ T K+ K A ++ K P
Sbjct: 209 ALTTPKEPTPTTPKEP--ASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA-PT 265
Query: 650 KAKDSAKTTEETSKP 664
K+ A TT + P
Sbjct: 266 TTKEPAPTTPKEPAP 280
Score = 30.4 bits (67), Expect = 5.5
Identities = 59/258 (22%), Positives = 85/258 (32%), Gaps = 45/258 (17%)
Query: 3 PTETKAVKTEPEKKSQSTKPK----SLPKQASDTGSNDAHNKKAVSRSAEQQP---SEKS 55
PT TK + K T PK + PK+ + T KK + E P SE S
Sbjct: 670 PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP-----KKPAPTTPETPPPTTSEVS 724
Query: 56 TEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAA 115
T TK I + +S +P K E P VP P AA
Sbjct: 725 TPTTTKEPTTIHKSPDE--STPELSAEPTPKALENSPKEPGVPTTKTP----------AA 772
Query: 116 LDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRE--LLAKKEG 173
+ T + TE + T P ++T ++ K T K E + A
Sbjct: 773 TKPEMTTTAKDKTTERDLRT-------TPETTTAAPKMTKETATTTEKTTESKITATTTQ 825
Query: 174 ITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKT-------EKEESTEVLKAQSAGT 226
+T + P I L + T KKT K E T K ++ +
Sbjct: 826 VTSTTTQDTTPF----KITTLKTT-TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS 880
Query: 227 VRSAAPPQEKKRKVEKDT 244
+ PQ+ + +K T
Sbjct: 881 KATTPKPQKPTKAPKKPT 898
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 61.2 bits (147), Expect = 3e-09
Identities = 148/702 (21%), Positives = 226/702 (32%), Gaps = 113/702 (16%)
Query: 3 PTETKAVKTEPEKKSQSTKPK---SLPKQASDTGSND---AHNKKAVSRSAEQQPSEKST 56
PT TK+ T P++ + +T + + PK+ + T + + K A + E P+
Sbjct: 290 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 349
Query: 57 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 116
T P++ + T +P KE TP P + P KP+ + + A
Sbjct: 350 PAPTTPKEPAPTTPKEPTPTT--PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA- 406
Query: 117 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG 176
P +E T T +P +T E + P +E
Sbjct: 407 ---------PTTPKEPAPTTT----KEPSPTTPKEPAPTTTKSAPTTTKE--------PA 445
Query: 177 PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 236
P S P P + + + +P T K+ + K + T + AP K
Sbjct: 446 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 505
Query: 237 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDE--AKAKEEKLEKCGEDDETI 294
K +A ++ P + E A E+L ++ T
Sbjct: 506 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 565
Query: 295 PSEYRLKPATDKDGKPLLPE------PEE-------KPKPRSESELIDELSEDFDRSECK 341
+ P T K P P+ P+E +P P + E + + K
Sbjct: 566 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 625
Query: 342 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 401
E P+ T K K AP E T C P P T KGT P E +
Sbjct: 626 E-PAPTTPKKPAPKELAPTTTKEPTSTT--CD----KPAPTTPKGTAPTTPKEPAPTT-- 676
Query: 402 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 461
KE P K ++ +K KE + P KP P KE
Sbjct: 677 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE--LAPTTTKGPTSTTSDKP-APTTPKET 733
Query: 462 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 521
P ++ P + K + +TP TT + P T +
Sbjct: 734 APTTPKE------------PAPTTPKK---------PAPTTPETPPPTTSEVSTPTTTKE 772
Query: 522 S---DKDLDDALDKLSDSLGQRQPDPDENKPMEDKV---------KEKAKAEHRDKLGER 569
K D++ +LS + P EN P E V K + +DK ER
Sbjct: 773 PTTIHKSPDESTPELS---AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 829
Query: 570 DDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQN 629
D PE K T+K+ +SK A + T+ T+Q+
Sbjct: 830 DLRTTPETTTAAPK--MTKETATTTEKTTESKITA-------------TTTQVTSTTTQD 874
Query: 630 TAKDKCKKAASSSKAPKNGGKAKDSAKT-----TEETSKPKD 666
T K +++ APK K T EET+KPKD
Sbjct: 875 TTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKD 916
Score = 55.5 bits (132), Expect = 2e-07
Identities = 134/679 (19%), Positives = 214/679 (31%), Gaps = 75/679 (11%)
Query: 4 TETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQ 63
T + T P++ + +T + P + ++SA P E + P T +
Sbjct: 253 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA--PTTTKE 310
Query: 64 DMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTL 123
+ E T +P + TP P + P KP+ + +
Sbjct: 311 PAPTTPKEPAPTTTK---EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE---------- 357
Query: 124 GGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSK 183
P T + T T P+ P + K PK KE PA
Sbjct: 358 --PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-----PA---- 406
Query: 184 PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKD 243
P P + + + + +P T K T + T + P+E K+
Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 466
Query: 244 ----TMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYR 299
T + A T EP + KE K+ E T P E
Sbjct: 467 PAPTTPKEPAPTTPKKPAPTTPKEPAPT--TPKEPAPTTTKKPAPTTPKEPAPTTPKE-- 522
Query: 300 LKPATDKDGKPLLPEP-----EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES 354
P T K P PE EKP P + EL E+ P+ P E +
Sbjct: 523 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE-------PTPTTPEEPAPTT 575
Query: 355 -KAAAPAPVSEAVCRTSMCSIQSAPPEPA--TLKGTVPDDAVEALADSLGKKEADPEDGK 411
KAAAP E T + P EPA T K T P + A + K+ A K
Sbjct: 576 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKK 634
Query: 412 PVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES-----KEQLPPMS 466
P ++ +E +K P K P PKE KE P
Sbjct: 635 PAPKELAPTTTKEPTSTTCDKPAPTTP---------KGTAPTTPKEPAPTTPKEPAPTTP 685
Query: 467 EDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDL 526
+ L E P + K +LA ++ + T + P + K+
Sbjct: 686 KGTAPTTLKE----PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 741
Query: 527 DDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQ 586
K P P ++ ++ H+ D++ P +
Sbjct: 742 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP----DESTPELSAEPTPKALE 797
Query: 587 DKPVKP--PTKKSEDSKKPADDQDPIDALSG-DLDSCPSTTETSQNTAKDKCKKAASSSK 643
+ P +P PT K+ + KP D + DL + P TT + K+ +++
Sbjct: 798 NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTE 857
Query: 644 APKNGGKAKDSAKTTEETS 662
+ + ++ TT++T+
Sbjct: 858 SKITATTTQVTSTTTQDTT 876
Score = 50.4 bits (119), Expect = 5e-06
Identities = 101/497 (20%), Positives = 164/497 (32%), Gaps = 36/497 (7%)
Query: 183 KPIGPDDAIDALSS-DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVE 241
KP D+A L + DF +P + + K ++ + R + PP K
Sbjct: 122 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 181
Query: 242 KDTMSDQA-LEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 300
T++ + +E + +Q + KE + + + +EK D S+
Sbjct: 182 SLTVNKETTVETKETTTTNKQTSTDG-----KEKTTSAKETQSIEKTSAKDLAPTSKVLA 236
Query: 301 KPATDKDGK---PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAA 357
KP + P L P+E P P + E ++ + K P+ P E + +
Sbjct: 237 KPTPKAETTTKGPALTTPKE-PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 295
Query: 358 APAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKV 417
AP E T+ + P EPA P A + K+ A KP
Sbjct: 296 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 355
Query: 418 KEKAKEEDREKL-GEKEETIPPDYRLEEVKDKDGKPLLPKE-----SKEQLPPMSEDFLL 471
KE A +E +E P K+ P PK+ KE P ++
Sbjct: 356 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 415
Query: 472 DALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAP--PRDTS-QSDKDLDD 528
E + + E A + ++ PA TT AP P++ S + K+
Sbjct: 416 TTTKEP------SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469
Query: 529 ALDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQD 587
K ++P P K P KE A + + T P E
Sbjct: 470 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK----KPAPTTPKEPAPTTPKETAP 525
Query: 588 KPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKN 647
K T + + P + P +L P+T E T ++ + AP
Sbjct: 526 TTPKKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNT 583
Query: 648 GGKAKDSAKTTEETSKP 664
K+ A TT + P
Sbjct: 584 ---PKEPAPTTPKEPAP 597
Score = 44.3 bits (103), Expect = 4e-04
Identities = 57/267 (21%), Positives = 93/267 (34%), Gaps = 15/267 (5%)
Query: 175 TGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQ 234
T P ++KPI P ++ S S T + T + + T Q++ +
Sbjct: 155 TSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA 214
Query: 235 EKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETI 294
++ + +EK + D A + + T +AE ++ E K E
Sbjct: 215 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 274
Query: 295 PSEYRLKPATDKDGKPL------------LPEPEEKPKPRSESELIDELSEDFDRSECKE 342
P+ + P T K+ P P ++P P + E +++ + K
Sbjct: 275 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 334
Query: 343 KPSKPTEKTEES-KAAAPAPVSEAVCRTSMCSIQSAPPEPA-TLKGTVPDDAVEALADSL 400
P+ P E + K AP E T + P EPA T K P E A +
Sbjct: 335 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-APTA 393
Query: 401 GKKEADPEDGKPVMDKVKEKAKEEDRE 427
KK A +P KE A +E
Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKE 420
Score = 32.0 bits (71), Expect = 1.9
Identities = 54/255 (21%), Positives = 93/255 (36%), Gaps = 21/255 (8%)
Query: 419 EKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDF 478
E+ +E D + +K + PDY + KD K K+ PP+ + E
Sbjct: 79 ERGRECDCDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPKPPV--------VDEAG 130
Query: 479 SGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDT--SQSDKDLDDALDKLSDS 536
SG N K + VS +P TT PR + SD + +L ++
Sbjct: 131 SGLDN-GDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 189
Query: 537 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT--IPPEYRHLLDDNGQ-DKPVKPP 593
+ + NK KEK + + E+ + P + L + + K P
Sbjct: 190 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP 249
Query: 594 TKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKC----KKAASSSKAPKNGG 649
+ P ++P A + + P+T +++ T K+ K A ++ K P
Sbjct: 250 ALTTPKEPTPTTPKEP--ASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA-PT 306
Query: 650 KAKDSAKTTEETSKP 664
K+ A TT + P
Sbjct: 307 TTKEPAPTTPKEPAP 321
Score = 30.4 bits (67), Expect = 5.5
Identities = 59/258 (22%), Positives = 85/258 (32%), Gaps = 45/258 (17%)
Query: 3 PTETKAVKTEPEKKSQSTKPK----SLPKQASDTGSNDAHNKKAVSRSAEQQP---SEKS 55
PT TK + K T PK + PK+ + T KK + E P SE S
Sbjct: 711 PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP-----KKPAPTTPETPPPTTSEVS 765
Query: 56 TEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAA 115
T TK I + +S +P K E P VP P AA
Sbjct: 766 TPTTTKEPTTIHKSPDE--STPELSAEPTPKALENSPKEPGVPTTKTP----------AA 813
Query: 116 LDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRE--LLAKKEG 173
+ T + TE + T P ++T ++ K T K E + A
Sbjct: 814 TKPEMTTTAKDKTTERDLRT-------TPETTTAAPKMTKETATTTEKTTESKITATTTQ 866
Query: 174 ITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKT-------EKEESTEVLKAQSAGT 226
+T + P I L + T KKT K E T K ++ +
Sbjct: 867 VTSTTTQDTTPF----KITTLKTT-TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS 921
Query: 227 VRSAAPPQEKKRKVEKDT 244
+ PQ+ + +K T
Sbjct: 922 KATTPKPQKPTKAPKKPT 939
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 61.2 bits (147), Expect = 3e-09
Identities = 148/702 (21%), Positives = 226/702 (32%), Gaps = 113/702 (16%)
Query: 3 PTETKAVKTEPEKKSQSTKPK---SLPKQASDTGSND---AHNKKAVSRSAEQQPSEKST 56
PT TK+ T P++ + +T + + PK+ + T + + K A + E P+
Sbjct: 342 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 401
Query: 57 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 116
T P++ + T +P KE TP P + P KP+ + + A
Sbjct: 402 PAPTTPKEPAPTTPKEPTPTT--PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA- 458
Query: 117 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG 176
P +E T T +P +T E + P +E
Sbjct: 459 ---------PTTPKEPAPTTT----KEPSPTTPKEPAPTTTKSAPTTTKE--------PA 497
Query: 177 PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 236
P S P P + + + +P T K+ + K + T + AP K
Sbjct: 498 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 557
Query: 237 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDE--AKAKEEKLEKCGEDDETI 294
K +A ++ P + E A E+L ++ T
Sbjct: 558 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 617
Query: 295 PSEYRLKPATDKDGKPLLPE------PEE-------KPKPRSESELIDELSEDFDRSECK 341
+ P T K P P+ P+E +P P + E + + K
Sbjct: 618 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 677
Query: 342 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 401
E P+ T K K AP E T C P P T KGT P E +
Sbjct: 678 E-PAPTTPKKPAPKELAPTTTKEPTSTT--CD----KPAPTTPKGTAPTTPKEPAPTT-- 728
Query: 402 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 461
KE P K ++ +K KE + P KP P KE
Sbjct: 729 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE--LAPTTTKGPTSTTSDKP-APTTPKET 785
Query: 462 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 521
P ++ P + K + +TP TT + P T +
Sbjct: 786 APTTPKE------------PAPTTPKK---------PAPTTPETPPPTTSEVSTPTTTKE 824
Query: 522 S---DKDLDDALDKLSDSLGQRQPDPDENKPMEDKV---------KEKAKAEHRDKLGER 569
K D++ +LS + P EN P E V K + +DK ER
Sbjct: 825 PTTIHKSPDESTPELS---AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 881
Query: 570 DDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQN 629
D PE K T+K+ +SK A + T+ T+Q+
Sbjct: 882 DLRTTPETTTAAPK--MTKETATTTEKTTESKITA-------------TTTQVTSTTTQD 926
Query: 630 TAKDKCKKAASSSKAPKNGGKAKDSAKT-----TEETSKPKD 666
T K +++ APK K T EET+KPKD
Sbjct: 927 TTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKD 968
Score = 57.4 bits (137), Expect = 4e-08
Identities = 124/625 (19%), Positives = 209/625 (33%), Gaps = 60/625 (9%)
Query: 55 STEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDA 114
++ P +K S +++ T S KP +KKK KK + E ++ S ++
Sbjct: 70 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKK----VIESEEITEEHSVSENQES 125
Query: 115 ALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKR-EVTIPPKYRELLAKKEG 173
+ + +++ T ++ +S EL K+ +V K R KK+
Sbjct: 126 S-----------SSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNR---TKKKP 171
Query: 174 ITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPP 233
PP G D+ DF +P + + K ++ + R + PP
Sbjct: 172 TPKPPVVDEAGSGLDNG------DFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 225
Query: 234 QEKKRKVEKDTMSDQA-LEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDE 292
K T++ + +E + +Q + KE + + + +EK D
Sbjct: 226 NSDTSKETSLTVNKETTVETKETTTTNKQTSTDG-----KEKTTSAKETQSIEKTSAKDL 280
Query: 293 TIPSEYRLKPATDKDGK---PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTE 349
S+ KP + P L P+E P P + E ++ + K P+ P E
Sbjct: 281 APTSKVLAKPTPKAETTTKGPALTTPKE-PTPTTPKEPASTTPKEPTPTTIKSAPTTPKE 339
Query: 350 KTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPED 409
+ +AP E T+ + P EPA P A + K+ A
Sbjct: 340 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 399
Query: 410 GKPVMDKVKEKAKEEDREKL-GEKEETIPPDYRLEEVKDKDGKPLLPKE-----SKEQLP 463
KP KE A +E +E P K+ P PK+ KE P
Sbjct: 400 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 459
Query: 464 PMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAP--PRDTS- 520
++ E + + E A + ++ PA TT AP P++ S
Sbjct: 460 TTPKEPAPTTTKEP------SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 513
Query: 521 QSDKDLDDALDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLGERDDTIPPEYRH 579
+ K+ K ++P P K P KE A + + T P E
Sbjct: 514 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK----KPAPTTPKEPAP 569
Query: 580 LLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAA 639
K T + + P + P +L P+T E T ++
Sbjct: 570 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTT 627
Query: 640 SSSKAPKNGGKAKDSAKTTEETSKP 664
+ AP K+ A TT + P
Sbjct: 628 PKAAAPNT---PKEPAPTTPKEPAP 649
Score = 55.5 bits (132), Expect = 2e-07
Identities = 134/679 (19%), Positives = 214/679 (31%), Gaps = 75/679 (11%)
Query: 4 TETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQ 63
T + T P++ + +T + P + ++SA P E + P T +
Sbjct: 305 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA--PTTTKE 362
Query: 64 DMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTL 123
+ E T +P + TP P + P KP+ + +
Sbjct: 363 PAPTTPKEPAPTTTK---EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE---------- 409
Query: 124 GGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSK 183
P T + T T P+ P + K PK KE PA
Sbjct: 410 --PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-----PA---- 458
Query: 184 PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKD 243
P P + + + + +P T K T + T + P+E K+
Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 518
Query: 244 ----TMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYR 299
T + A T EP + KE K+ E T P E
Sbjct: 519 PAPTTPKEPAPTTPKKPAPTTPKEPAPT--TPKEPAPTTTKKPAPTTPKEPAPTTPKE-- 574
Query: 300 LKPATDKDGKPLLPEP-----EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES 354
P T K P PE EKP P + EL E+ P+ P E +
Sbjct: 575 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE-------PTPTTPEEPAPTT 627
Query: 355 -KAAAPAPVSEAVCRTSMCSIQSAPPEPA--TLKGTVPDDAVEALADSLGKKEADPEDGK 411
KAAAP E T + P EPA T K T P + A + K+ A K
Sbjct: 628 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKK 686
Query: 412 PVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES-----KEQLPPMS 466
P ++ +E +K P K P PKE KE P
Sbjct: 687 PAPKELAPTTTKEPTSTTCDKPAPTTP---------KGTAPTTPKEPAPTTPKEPAPTTP 737
Query: 467 EDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDL 526
+ L E P + K +LA ++ + T + P + K+
Sbjct: 738 KGTAPTTLKE----PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 793
Query: 527 DDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQ 586
K P P ++ ++ H+ D++ P +
Sbjct: 794 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP----DESTPELSAEPTPKALE 849
Query: 587 DKPVKP--PTKKSEDSKKPADDQDPIDALSG-DLDSCPSTTETSQNTAKDKCKKAASSSK 643
+ P +P PT K+ + KP D + DL + P TT + K+ +++
Sbjct: 850 NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTE 909
Query: 644 APKNGGKAKDSAKTTEETS 662
+ + ++ TT++T+
Sbjct: 910 SKITATTTQVTSTTTQDTT 928
Score = 30.4 bits (67), Expect = 5.5
Identities = 59/258 (22%), Positives = 85/258 (32%), Gaps = 45/258 (17%)
Query: 3 PTETKAVKTEPEKKSQSTKPK----SLPKQASDTGSNDAHNKKAVSRSAEQQP---SEKS 55
PT TK + K T PK + PK+ + T KK + E P SE S
Sbjct: 763 PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP-----KKPAPTTPETPPPTTSEVS 817
Query: 56 TEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAA 115
T TK I + +S +P K E P VP P AA
Sbjct: 818 TPTTTKEPTTIHKSPDE--STPELSAEPTPKALENSPKEPGVPTTKTP----------AA 865
Query: 116 LDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRE--LLAKKEG 173
+ T + TE + T P ++T ++ K T K E + A
Sbjct: 866 TKPEMTTTAKDKTTERDLRT-------TPETTTAAPKMTKETATTTEKTTESKITATTTQ 918
Query: 174 ITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKT-------EKEESTEVLKAQSAGT 226
+T + P I L + T KKT K E T K ++ +
Sbjct: 919 VTSTTTQDTTPF----KITTLKTT-TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS 973
Query: 227 VRSAAPPQEKKRKVEKDT 244
+ PQ+ + +K T
Sbjct: 974 KATTPKPQKPTKAPKKPT 991
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 61.2 bits (147), Expect = 3e-09
Identities = 148/702 (21%), Positives = 226/702 (32%), Gaps = 113/702 (16%)
Query: 3 PTETKAVKTEPEKKSQSTKPK---SLPKQASDTGSND---AHNKKAVSRSAEQQPSEKST 56
PT TK+ T P++ + +T + + PK+ + T + + K A + E P+
Sbjct: 383 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 442
Query: 57 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 116
T P++ + T +P KE TP P + P KP+ + + A
Sbjct: 443 PAPTTPKEPAPTTPKEPTPTT--PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA- 499
Query: 117 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG 176
P +E T T +P +T E + P +E
Sbjct: 500 ---------PTTPKEPAPTTT----KEPSPTTPKEPAPTTTKSAPTTTKE--------PA 538
Query: 177 PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 236
P S P P + + + +P T K+ + K + T + AP K
Sbjct: 539 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 598
Query: 237 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDE--AKAKEEKLEKCGEDDETI 294
K +A ++ P + E A E+L ++ T
Sbjct: 599 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 658
Query: 295 PSEYRLKPATDKDGKPLLPE------PEE-------KPKPRSESELIDELSEDFDRSECK 341
+ P T K P P+ P+E +P P + E + + K
Sbjct: 659 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 718
Query: 342 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 401
E P+ T K K AP E T C P P T KGT P E +
Sbjct: 719 E-PAPTTPKKPAPKELAPTTTKEPTSTT--CD----KPAPTTPKGTAPTTPKEPAPTT-- 769
Query: 402 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 461
KE P K ++ +K KE + P KP P KE
Sbjct: 770 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE--LAPTTTKGPTSTTSDKP-APTTPKET 826
Query: 462 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 521
P ++ P + K + +TP TT + P T +
Sbjct: 827 APTTPKE------------PAPTTPKK---------PAPTTPETPPPTTSEVSTPTTTKE 865
Query: 522 S---DKDLDDALDKLSDSLGQRQPDPDENKPMEDKV---------KEKAKAEHRDKLGER 569
K D++ +LS + P EN P E V K + +DK ER
Sbjct: 866 PTTIHKSPDESTPELS---AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 922
Query: 570 DDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQN 629
D PE K T+K+ +SK A + T+ T+Q+
Sbjct: 923 DLRTTPETTTAAPK--MTKETATTTEKTTESKITA-------------TTTQVTSTTTQD 967
Query: 630 TAKDKCKKAASSSKAPKNGGKAKDSAKT-----TEETSKPKD 666
T K +++ APK K T EET+KPKD
Sbjct: 968 TTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKD 1009
Score = 57.4 bits (137), Expect = 4e-08
Identities = 124/625 (19%), Positives = 209/625 (33%), Gaps = 60/625 (9%)
Query: 55 STEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDA 114
++ P +K S +++ T S KP +KKK KK + E ++ S ++
Sbjct: 111 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKK----VIESEEITEEHSVSENQES 166
Query: 115 ALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKR-EVTIPPKYRELLAKKEG 173
+ + +++ T ++ +S EL K+ +V K R KK+
Sbjct: 167 S-----------SSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNR---TKKKP 212
Query: 174 ITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPP 233
PP G D+ DF +P + + K ++ + R + PP
Sbjct: 213 TPKPPVVDEAGSGLDNG------DFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 266
Query: 234 QEKKRKVEKDTMSDQA-LEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDE 292
K T++ + +E + +Q + KE + + + +EK D
Sbjct: 267 NSDTSKETSLTVNKETTVETKETTTTNKQTSTDG-----KEKTTSAKETQSIEKTSAKDL 321
Query: 293 TIPSEYRLKPATDKDGK---PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTE 349
S+ KP + P L P+E P P + E ++ + K P+ P E
Sbjct: 322 APTSKVLAKPTPKAETTTKGPALTTPKE-PTPTTPKEPASTTPKEPTPTTIKSAPTTPKE 380
Query: 350 KTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPED 409
+ +AP E T+ + P EPA P A + K+ A
Sbjct: 381 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 440
Query: 410 GKPVMDKVKEKAKEEDREKL-GEKEETIPPDYRLEEVKDKDGKPLLPKE-----SKEQLP 463
KP KE A +E +E P K+ P PK+ KE P
Sbjct: 441 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 500
Query: 464 PMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAP--PRDTS- 520
++ E + + E A + ++ PA TT AP P++ S
Sbjct: 501 TTPKEPAPTTTKEP------SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 554
Query: 521 QSDKDLDDALDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLGERDDTIPPEYRH 579
+ K+ K ++P P K P KE A + + T P E
Sbjct: 555 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK----KPAPTTPKEPAP 610
Query: 580 LLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAA 639
K T + + P + P +L P+T E T ++
Sbjct: 611 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTT 668
Query: 640 SSSKAPKNGGKAKDSAKTTEETSKP 664
+ AP K+ A TT + P
Sbjct: 669 PKAAAPNT---PKEPAPTTPKEPAP 690
Score = 55.5 bits (132), Expect = 2e-07
Identities = 134/679 (19%), Positives = 214/679 (31%), Gaps = 75/679 (11%)
Query: 4 TETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQ 63
T + T P++ + +T + P + ++SA P E + P T +
Sbjct: 346 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA--PTTTKE 403
Query: 64 DMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTL 123
+ E T +P + TP P + P KP+ + +
Sbjct: 404 PAPTTPKEPAPTTTK---EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE---------- 450
Query: 124 GGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSK 183
P T + T T P+ P + K PK KE PA
Sbjct: 451 --PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-----PA---- 499
Query: 184 PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKD 243
P P + + + + +P T K T + T + P+E K+
Sbjct: 500 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 559
Query: 244 ----TMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYR 299
T + A T EP + KE K+ E T P E
Sbjct: 560 PAPTTPKEPAPTTPKKPAPTTPKEPAPT--TPKEPAPTTTKKPAPTTPKEPAPTTPKE-- 615
Query: 300 LKPATDKDGKPLLPEP-----EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES 354
P T K P PE EKP P + EL E+ P+ P E +
Sbjct: 616 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE-------PTPTTPEEPAPTT 668
Query: 355 -KAAAPAPVSEAVCRTSMCSIQSAPPEPA--TLKGTVPDDAVEALADSLGKKEADPEDGK 411
KAAAP E T + P EPA T K T P + A + K+ A K
Sbjct: 669 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKK 727
Query: 412 PVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES-----KEQLPPMS 466
P ++ +E +K P K P PKE KE P
Sbjct: 728 PAPKELAPTTTKEPTSTTCDKPAPTTP---------KGTAPTTPKEPAPTTPKEPAPTTP 778
Query: 467 EDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDL 526
+ L E P + K +LA ++ + T + P + K+
Sbjct: 779 KGTAPTTLKE----PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 834
Query: 527 DDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQ 586
K P P ++ ++ H+ D++ P +
Sbjct: 835 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP----DESTPELSAEPTPKALE 890
Query: 587 DKPVKP--PTKKSEDSKKPADDQDPIDALSG-DLDSCPSTTETSQNTAKDKCKKAASSSK 643
+ P +P PT K+ + KP D + DL + P TT + K+ +++
Sbjct: 891 NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTE 950
Query: 644 APKNGGKAKDSAKTTEETS 662
+ + ++ TT++T+
Sbjct: 951 SKITATTTQVTSTTTQDTT 969
Score = 30.4 bits (67), Expect = 5.5
Identities = 59/258 (22%), Positives = 85/258 (32%), Gaps = 45/258 (17%)
Query: 3 PTETKAVKTEPEKKSQSTKPK----SLPKQASDTGSNDAHNKKAVSRSAEQQP---SEKS 55
PT TK + K T PK + PK+ + T KK + E P SE S
Sbjct: 804 PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP-----KKPAPTTPETPPPTTSEVS 858
Query: 56 TEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAA 115
T TK I + +S +P K E P VP P AA
Sbjct: 859 TPTTTKEPTTIHKSPDE--STPELSAEPTPKALENSPKEPGVPTTKTP----------AA 906
Query: 116 LDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRE--LLAKKEG 173
+ T + TE + T P ++T ++ K T K E + A
Sbjct: 907 TKPEMTTTAKDKTTERDLRT-------TPETTTAAPKMTKETATTTEKTTESKITATTTQ 959
Query: 174 ITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKT-------EKEESTEVLKAQSAGT 226
+T + P I L + T KKT K E T K ++ +
Sbjct: 960 VTSTTTQDTTPF----KITTLKTT-TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS 1014
Query: 227 VRSAAPPQEKKRKVEKDT 244
+ PQ+ + +K T
Sbjct: 1015 KATTPKPQKPTKAPKKPT 1032
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 61.2 bits (147), Expect = 3e-09
Identities = 105/533 (19%), Positives = 189/533 (35%), Gaps = 82/533 (15%)
Query: 178 PADSSKPI-----GPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAP 232
P +S+P G D++ D SS GS +++G +E E S+ +A S P
Sbjct: 407 PGSNSEPSHHNSEGADNSRDDSSSH--SGSESSSGSDSESESSSSDSEANEPSQSASPEP 464
Query: 233 PQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDE 292
K + D ++ + + P + S + KE + + G
Sbjct: 465 EPPPTNKWQLDNWLNK--------VNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNS-- 514
Query: 293 TIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTE 352
TD G P+ P +S+ I + SE + S T +
Sbjct: 515 ----------YTDTSG----PKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRR 560
Query: 353 ESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGK---KEADPED 409
P +A ++ P L ++P +A K K+
Sbjct: 561 TVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSS 620
Query: 410 GKPVMDKVKEKAKEEDREKLGE------------KEETIPPDYRLEEVKDKDGKPLLPKE 457
+P +K K K+ + +K E + E++PP + + + + P+ P
Sbjct: 621 PRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSS 680
Query: 458 SKEQ--------LPPMSEDFLLDALSEDFSGPQNASSL--KFEDAKLAAAISEVVSQT-P 506
+E+ PM E LL LSE P + L K + L + +T P
Sbjct: 681 VEEEDSFFRQRMFSPMEEKELLSPLSE----PDDRYPLIVKIDLNLLTRIPGKPYKETEP 736
Query: 507 ASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKL 566
+ P + T ++ K A +K+S+ ++ + D+N+ E K K K E ++
Sbjct: 737 PKGEKKNVPEKHTREAQKQ---ASEKVSNKGKRKHKNEDDNRASESK---KPKTEDKNSA 790
Query: 567 GERDDT-------IPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 619
G + + + + LL P K P + K+ + + S
Sbjct: 791 GHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKE 850
Query: 620 CPSTTETSQNTAKDKCKKAASSS-------KAPKNGGKAKDSAKTTEETSKPK 665
+++ S +T+K K + +SS KAP + SA T ++SKP+
Sbjct: 851 TSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTL-DSSKPR 902
Score = 56.2 bits (134), Expect = 9e-08
Identities = 120/594 (20%), Positives = 201/594 (33%), Gaps = 132/594 (22%)
Query: 3 PTETKAVKTEPEKKSQSTKPKSLPKQASDTGS-----NDAHNKKAVSRSAEQQPSEK-ST 56
P T +EP + S +S +GS +D+ ++ + S S +PS+ S
Sbjct: 403 PRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASP 462
Query: 57 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSG--KSGMDA 114
EP+ P + K ++PA V+S G K G +
Sbjct: 463 EPEPPPTNKWQLDNWL-------------NKVNPHKVSPASSVDSNIPSSQGYKKEGREQ 509
Query: 115 ALDDLIDTLGGPEET------EEENTTYTGPE--------VSDPMSSTYIEELGKREVTI 160
+ GP+ET + T G E + S+T +GK++
Sbjct: 510 GTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQ--- 566
Query: 161 PPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLK 220
PK E A +E G +S P+ D P++ K K +K
Sbjct: 567 -PKKAEKAAAEEPRGGLKIESETPV-----------DLASSMPSSRHKAATKGSRKPNIK 614
Query: 221 AQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAK 280
+S +S+ P +K+K + + S Q R I E D + +
Sbjct: 615 KES----KSSPRPTAEKKKYKSTSKSSQ------------------KSREIIETDTSSSD 652
Query: 281 EEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP---------KPRSESELIDEL 331
++ E++P + + + P+ P E+ P E EL+ L
Sbjct: 653 -------SDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPL 705
Query: 332 SEDFDRSECKEK---------PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPA 382
SE DR K P KP ++TE K + PE
Sbjct: 706 SEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGE-----------------KKNVPEKH 748
Query: 383 TLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRL 442
T + A E +++ +K + +D + K K K ED+ G K + +
Sbjct: 749 TRE--AQKQASEKVSNKGKRKHKNEDDNRASESK---KPKTEDKNSAGHKPSSNRESSKQ 803
Query: 443 EEVKDKD--GKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISE 500
K+KD P P SK+ P +S+ S +++S K
Sbjct: 804 SAAKEKDLLPSPAGPVPSKD--PKTEHGSRKRTISQSSSLKSSSNSNKETSGS------- 854
Query: 501 VVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKV 554
S+ +ST++ TS S K++ + S + P D +KP K+
Sbjct: 855 --SKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKL 906
>gi|109637791 transcription factor-like nuclear regulator [Homo
sapiens]
Length = 2624
Score = 60.5 bits (145), Expect = 5e-09
Identities = 84/363 (23%), Positives = 150/363 (41%), Gaps = 50/363 (13%)
Query: 204 TAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMS-DQALEALSASLGTRQA 262
T+ + E +T+ +++ T R A P+EK V DT+ + L+A+ + R+
Sbjct: 855 TSPKEMVPAEINTKEMQSDLKETGRRAISPREKILDVIDDTIEMETGLKAMGREICLREK 914
Query: 263 EPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPR 322
PE+ +D + ++ LE+ G R + + K+G PEE KP
Sbjct: 915 TPEV-------IDATEEIDKDLEEAG----------RREISPQKNG------PEEV-KPL 950
Query: 323 SESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPA 382
E E +L + S +EK + T+ TEE + + + T I P
Sbjct: 951 GEVET--DLKATGNESSPREKTPEVTDATEE--------IDKNLEETGRRKISPRENGPE 1000
Query: 383 TLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRL 442
+K P D +E ++ G++ + E V+D +E EE + E P + L
Sbjct: 1001 EVK---PVDEMETDLNATGRESSPREKTPEVIDATEEIDLEET------EREVSPQENGL 1051
Query: 443 EEVKDK-DGKPLLPKESKEQLPPMSEDFLLDALSE---DFSGPQNASSLKFEDAKLAAAI 498
EEVK + + L ++ P ++DA+ E D + S + + +
Sbjct: 1052 EEVKPLGEMETDLKATGRDSFPRGKTPEVIDAIEEIEIDLEETEREISPQENGLEEVKPL 1111
Query: 499 SEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKA 558
E+ QT T PR+ + D + +DK + G+R+ P+EN P E K ++
Sbjct: 1112 GEM--QTDLKATGREISPREKTPEVIDATEEIDKDLEETGRREISPEENGPEEVKPVDEM 1169
Query: 559 KAE 561
+ +
Sbjct: 1170 ETD 1172
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 59.3 bits (142), Expect = 1e-08
Identities = 123/580 (21%), Positives = 209/580 (36%), Gaps = 102/580 (17%)
Query: 13 PEKKSQSTKP--KSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTK---PQDMIS 67
PE+K Q+ P K K+AS + S D+ ++ + P++K+ P + P +
Sbjct: 64 PERKLQANGPVAKKAKKKASSSDSEDSSEEE---EEVQGPPAKKAAVPAKRVGLPPGKAA 120
Query: 68 AGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPE 127
A + S ++ ++K+ + V ++K K K + D
Sbjct: 121 AKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDS-------DS 173
Query: 128 ETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGP 187
+E+E P+++ P++ K + PPK K G A SS
Sbjct: 174 SSEDEPPKNQKPKIT-PVTV-------KAQTKAPPKPARAAPKIAN--GKAASSSSSSSS 223
Query: 188 DDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSD 247
+ D + +P KKT ++ V KA V++A P K E D+ SD
Sbjct: 224 SSSSDDSEEEKAAATP----KKTVPKKQV-VAKAP----VKAATTPTRKSSSSE-DSSSD 273
Query: 248 QALEALS---------ASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGE--DDETIPS 296
+ E +S+ A P + +A K++ +E + D+ S
Sbjct: 274 EEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSS 333
Query: 297 EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 356
E KP T K ++ + KP P ++ S D D SE E PSKP T+ S +
Sbjct: 334 EEEKKPPT----KAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNS-S 388
Query: 357 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 416
PA +++ PA P V G+ ++ +
Sbjct: 389 NKPAVTTKS---------------PAVKPAAAPKQPVGG--------------GQKLLTR 419
Query: 417 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLD---A 473
+ + E+ E+E+T + K K +Q P S D D +
Sbjct: 420 KADSSSSEEESSSSEEEKT---KKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSS 476
Query: 474 LSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKL 533
SE+ + S++K + K+A PAS + A ++S SD ++ +KL
Sbjct: 477 SSEEEEEKTSKSAVKKKPQKVAGG---AAPSKPASAKKGKAESSNSSSSDDSSEEEEEKL 533
Query: 534 SDSLGQRQPDPDEN-------------KPMEDKVKEKAKA 560
R P N K E++ +EK KA
Sbjct: 534 KGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKA 573
Score = 55.8 bits (133), Expect = 1e-07
Identities = 84/379 (22%), Positives = 139/379 (36%), Gaps = 67/379 (17%)
Query: 337 RSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEAL 396
+++ K S + +EE + P +A + PP A K + + E+
Sbjct: 77 KAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGL---PPGKAAAKASESSSSEESS 133
Query: 397 ADSLGKKEADPEDGK--PVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 454
D D ED K PV VK +AK K D E+ K+ KP +
Sbjct: 134 DDD------DEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKI 187
Query: 455 -----------PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVS 503
P + P ++ A S S ++SS E+ K AA + V
Sbjct: 188 TPVTVKAQTKAPPKPARAAPKIANG---KAASSSSSSSSSSSSDDSEEEKAAATPKKTVP 244
Query: 504 Q----TPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQ-----------PDPDEN- 547
+ A A P R +S S+ D ++ + + P P ++
Sbjct: 245 KKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSL 304
Query: 548 --KPMEDKVKEKAKAEHRDKLGERDDTIPPEYRH----LLDDNGQDKPVKPPTKKSEDSK 601
+P + V+++ E + + D+ E + + KP PP KK+ +S
Sbjct: 305 GTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKP--PPAKKAAESS 362
Query: 602 KPADDQDPIDALSGDLDSCPS----TTETSQN----TAKDKCKKAASSSKAPKNGG---- 649
+ D D S + D PS TT+ S N T K K A++ K P GG
Sbjct: 363 SDSSDSD-----SSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLL 417
Query: 650 -KAKDSAKTTEETSKPKDD 667
+ DS+ + EE+S +++
Sbjct: 418 TRKADSSSSEEESSSSEEE 436
Score = 45.8 bits (107), Expect = 1e-04
Identities = 68/365 (18%), Positives = 130/365 (35%), Gaps = 62/365 (16%)
Query: 3 PTETKAVKTEPEKKS-QSTKPKSLPKQASDTGSNDAHNKK------AVSRSAEQQP-SEK 54
P K++ T+P KK+ + +P + +SD + + +K VS++ + P ++K
Sbjct: 298 PPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKK 357
Query: 55 STEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDA 114
+ E + D S+ + A + K K + +PAV + P +P G
Sbjct: 358 AAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGG---- 413
Query: 115 ALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGI 174
L+ +EEE+++ + +++T + K +++P K
Sbjct: 414 --QKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAK----------- 460
Query: 175 TGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQ 234
P G D+ SSD S +KT K + + + AG + P
Sbjct: 461 -------QAPQGSRDS----SSDSDSSSSEEEEEKTSKS-AVKKKPQKVAGGAAPSKPAS 508
Query: 235 EKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETI 294
KK K E S D ++ +EEKL+ G
Sbjct: 509 AKKGKAESSNSSSSD-------------------------DSSEEEEEKLKGKGSPRPQA 543
Query: 295 PSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES 354
P T ++GK EE+ + + + ++ + R + + T + ++
Sbjct: 544 PKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKI 603
Query: 355 KAAAP 359
K P
Sbjct: 604 KLQTP 608
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 57.4 bits (137), Expect = 4e-08
Identities = 128/653 (19%), Positives = 239/653 (36%), Gaps = 120/653 (18%)
Query: 16 KSQSTKPKSLPKQASDTGSNDAHNKKA-VSRSAEQQPSEKSTEPKTKPQDM--------- 65
K Q K + K D + A + A ++ E Q S+ + + K QD
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKEL 62
Query: 66 --ISAGGESV-AGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDT 122
+S + + A ++ KP + +E+ + SK K G+ G + DD
Sbjct: 63 EELSLEAQGIKADRETVAVKPTENNEEEFT--------SKDKKKKGQKGKKQSFDD---- 110
Query: 123 LGGPEETEEENTTY---TGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPA 179
EE E++++ P+V S ++ K K ++ K +G +
Sbjct: 111 -NDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDG-SEEDE 168
Query: 180 DSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRK 239
D+SK I I++ +K +K+ K + + S + K
Sbjct: 169 DNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQ----KNKPGPNIESGNEDDDASFK 224
Query: 240 VEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYR 299
++ T++ + E R E + LR +KE +E + ++ K E E
Sbjct: 225 IK--TVAQKKAEKKERERKKRDEE-KAKLRKLKEKEELETGKKDQSKQKESQRKFEEETV 281
Query: 300 LKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 359
T G ++P EEK + + +E D+ D + + K+K + EK +E K
Sbjct: 282 KSKVTVDTG--VIPASEEKAETPTAAE--DDNEGDKKKKDKKKKKGEKEEKEKEKKKG-- 335
Query: 360 APVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKE 419
P AT+K +A+ L + +++ + E+ +++++
Sbjct: 336 -------------------PSKATVKAM--QEALAKLKEEEERQKREEEERIKRLEELEA 374
Query: 420 KAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKE---------------------- 457
K KEE+R + ++E + +E K+GK L +
Sbjct: 375 KRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVP 434
Query: 458 SKEQLP---PMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPAS--TTQA 512
SK+ LP P+ ED + + + + S++ L AA+ + P T
Sbjct: 435 SKDSLPKKRPIYEDKKRKKIPQQLESKEVSESME-----LCAAVEVMEQGVPEKEETPPP 489
Query: 513 GAPPRDTSQSDKDLDDALDKLSDSLGQR---------------QPDPDENKPMEDKVKEK 557
P + D LDD SD ++ + + +E + ED+ E+
Sbjct: 490 VEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEE 549
Query: 558 AKAEHRDKLG----ERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADD 606
+ E + G E D+ + E D+G+ KP + S DS+ +DD
Sbjct: 550 EEEEEGESEGSEGDEEDEKVSDE-----KDSGKTLDKKPSKEMSSDSEYDSDD 597
Score = 55.8 bits (133), Expect = 1e-07
Identities = 119/567 (20%), Positives = 213/567 (37%), Gaps = 90/567 (15%)
Query: 12 EPEKKSQSTKPKSLPKQASDTGSNDAHN-----KKAVSRSAEQQPS------EKSTEPKT 60
E E K +K + PK +GS+D + KKA ++ + ++ K
Sbjct: 115 ELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKI 174
Query: 61 KPQDMISAGGESV-AGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDL 119
K + I++ GES + + G KK +K P + ++ D S K
Sbjct: 175 KERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFK---------- 224
Query: 120 IDTLGGPEETEEENTTYTGPEVSDPMSSTYIEE---LGKREVTIPPKYRELLAKKEGITG 176
I T+ + ++E E + +E GK++ + K +E K E T
Sbjct: 225 IKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQS---KQKESQRKFEEETV 281
Query: 177 PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 236
SK I A S+ +PTAA E ++ + K + +EK
Sbjct: 282 ----KSKVTVDTGVIPA--SEEKAETPTAAEDDNEGDKKKKDKKKKKG---EKEEKEKEK 332
Query: 237 KRKVEKDTMS--DQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETI 294
K+ K T+ +AL L ++ E E ++ ++E++ + +EE+LE+ + +
Sbjct: 333 KKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQ-EKRERKK 391
Query: 295 PSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES 354
E K K+GK LL + + + + R+E+ L ++ + P K ++
Sbjct: 392 QKEKERKERLKKEGK-LLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKK 450
Query: 355 KAAAPAPVSEAVCRTSM--CSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKP 412
+ P + SM C+ AVE + + +KE P +P
Sbjct: 451 RKKIPQQLESKEVSESMELCA------------------AVEVMEQGVPEKEETPPPVEP 492
Query: 413 VMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLD 472
++ E A +D E + EET + ++ K+ P+E +E+ ED +
Sbjct: 493 EEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKEN----PEEEEEEEEEEEEDEESE 548
Query: 473 ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDK 532
E+ G S ED K++ D S K LD K
Sbjct: 549 E-EEEEEGESEGSEGDEEDEKVS----------------------DEKDSGKTLDKKPSK 585
Query: 533 LSDSLGQRQPDPDENKPMEDKVKEKAK 559
S + D D+++ E++ +KAK
Sbjct: 586 EMSS--DSEYDSDDDRTKEERAYDKAK 610
Score = 49.7 bits (117), Expect = 9e-06
Identities = 87/397 (21%), Positives = 150/397 (37%), Gaps = 50/397 (12%)
Query: 5 ETKAVKTEPEKKSQSTKPKSL----PKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
+ KA K E E+K + + L K+ +TG D +K R E++ + T
Sbjct: 230 QKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDT 289
Query: 61 KPQDMISAGGESVAGITAISG-KPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDA-ALDD 118
+I A E TA GDKKK+ K E + +K G S A+ +
Sbjct: 290 ---GVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQE 346
Query: 119 LIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRE------------ 166
+ L EE ++ + + + EE ++E K +E
Sbjct: 347 ALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGK 406
Query: 167 LLAKKEGITGPPADSSKPIGPDDAIDALSSD-FTCGSPTAAGKKTEK----------EES 215
LL K + A+++ + ++ S D P KK +K ES
Sbjct: 407 LLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSES 466
Query: 216 TEVLKA-----QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAE------- 263
E+ A Q PP E + + + + EA+++ T + E
Sbjct: 467 MELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIE 526
Query: 264 ----PELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKD-GKPLLPEPEEK 318
PE + +E +E + EE+ E+ GE + + E K + +KD GK L +P ++
Sbjct: 527 VKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKE 586
Query: 319 PKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESK 355
SE + D+ +++ +R+ K K + E SK
Sbjct: 587 MSSDSEYDSDDDRTKE-ERAYDKAKRRIEKRRLEHSK 622
Score = 39.3 bits (90), Expect = 0.012
Identities = 57/289 (19%), Positives = 115/289 (39%), Gaps = 24/289 (8%)
Query: 390 DDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEE----DREKLGEK-EETIPPDYRLEE 444
DD ++ L + + + D + V K E +EE D++K G+K ++ D EE
Sbjct: 56 DDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEE 115
Query: 445 VKDKDGKPLLPKESK-EQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVS 503
++DKD K + K E +D + L + G S+ K++ ++ S+ +
Sbjct: 116 LEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIK 175
Query: 504 QTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQP-----DPDENKPMEDKVKEKA 558
+ ++ + +SD+ L + + + P + D++ + K +
Sbjct: 176 E----RSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQK 231
Query: 559 KAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPAD---------DQDP 609
KAE +++ ++ D + R L + + K +K+ E +K + D
Sbjct: 232 KAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGV 291
Query: 610 IDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTT 658
I A ++ + + ++ K K KK K K K K +K T
Sbjct: 292 IPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKAT 340
Score = 37.0 bits (84), Expect = 0.059
Identities = 40/168 (23%), Positives = 77/168 (45%), Gaps = 26/168 (15%)
Query: 518 DTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEY 577
D+++ D DLD ++ + ++ +P ++K + K K+K + D L E ++ + E
Sbjct: 11 DSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEE-LSLEA 69
Query: 578 RHL-----------LDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTET 626
+ + ++N ++ K KK + KK + D + + L D DS
Sbjct: 70 QGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELE-DKDS------K 122
Query: 627 SQNTAKDKCKKAASS------SKAPKNG-GKAKDSAKTTEETSKPKDD 667
S+ TAK K + + S +K PK GKA+ S K + + + +D+
Sbjct: 123 SKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDN 170
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 56.6 bits (135), Expect = 7e-08
Identities = 107/476 (22%), Positives = 180/476 (37%), Gaps = 55/476 (11%)
Query: 229 SAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG 288
S+APP + E A + + S T ++ D S +++ E
Sbjct: 447 SSAPPSAPQSLPEPVA---SAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAP 503
Query: 289 EDDETIPSEYRLKPATDKDGKPLLPEPE-----EKPKPRSESELIDELSEDFDRSECKEK 343
E + ++++L K +P P PE E P+ ES+ + + + SE K+
Sbjct: 504 EPEPPTTNKWQLDNWLTKVSQPAAP-PEGPRSTEPPRRHPESKGSSDSATSQEHSESKDP 562
Query: 344 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADS---- 399
P K + K + AP P + C+ S Q PP+ T+ P V+A A +
Sbjct: 563 PPKSSSKAPRAPPEAPHP-GKRSCQKS--PAQQEPPQRQTVGTKQPKKPVKASARAGSRT 619
Query: 400 --LGKKEAD--PEDGKPVMDKVKEKAKEEDREKL---GEKEETIPPDYRLEEVKDKDGKP 452
G++E P + K K K K + R + E + +PP E+ K K P
Sbjct: 620 SLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPS--SEKKKHKSSLP 677
Query: 453 LL------PKESKEQLPPMS-EDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQ- 504
P+ +K+ + + E F L L+E P + S + + A + E +
Sbjct: 678 APSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKD 737
Query: 505 ---TPASTTQAGAPPRDT----SQSDKDLDDALDKLSD--SLGQRQPDPDENKPMEDK-- 553
P T+ +P RDT S K D L ++ G RQ ++ +P K
Sbjct: 738 RLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKH 797
Query: 554 VKEKAKAEHRDKLGERDDTIPPEYRHLLDDN--GQDKPVKPPTKKSEDSKKPADDQDP-- 609
EK ++ KL ++ E D+ +K +K + S S K + P
Sbjct: 798 SSEKRSSDSSSKLAKKR---KGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSR 854
Query: 610 --IDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSK 663
+ ++ P + +SQ AK K+ S +A G SA +T+ K
Sbjct: 855 PSSQSSKKEMLPPPPVSSSSQKPAKPALKR--SRREADTCGQDPPKSASSTKSNHK 908
Score = 43.5 bits (101), Expect = 6e-04
Identities = 124/605 (20%), Positives = 195/605 (32%), Gaps = 113/605 (18%)
Query: 13 PEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGES 72
P + + P+SLP+ + AH+ A S S S +E ++ D S E
Sbjct: 445 PSSSAPPSAPQSLPEPVA-----SAHSSSAESESTSDSDSSSDSESESSSSD--SEENEP 497
Query: 73 VAGITAISGKPGDKKKE-----KKSLTPAVPVE----SKPDK--PSGKSGMDAALDDLID 121
+ P K + K PA P E ++P + P K D+A
Sbjct: 498 LETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHS 557
Query: 122 TLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADS 181
P PE P GKR P +E ++ T P
Sbjct: 558 ESKDPPPKSSSKAPRAPPEAPHP---------GKRSCQKSPAQQEPPQRQTVGTKQPKKP 608
Query: 182 SKPIGPDDAIDALSSD-----FTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 236
K + +L + GS K K ++ +A ++ + A PP +
Sbjct: 609 VKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSE 668
Query: 237 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS 296
K+K +L A S +L EP D +D T P
Sbjct: 669 KKK------HKSSLPAPSKALS--GPEPAKD--------------------NVEDRT-PE 699
Query: 297 EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 356
+ L P T+ G P S C++ + + K
Sbjct: 700 HFALVPLTESQGPP-------------------HSGSGSRTSGCRQ---AVVVQEDSRKD 737
Query: 357 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGK--KEADPEDGKPVM 414
P P+ + T + S P P +L + D + + GK ++ ED +P
Sbjct: 738 RLPLPLRD----TKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPA 793
Query: 415 DK--VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPL-LPKESKEQLPPMSEDFLL 471
K EK + KL +K + E +D D K + L KE K Q S
Sbjct: 794 GKKHSSEKRSSDSSSKLAKKRKG-------EAERDCDNKKIRLEKEIKSQSSSSSSSHKE 846
Query: 472 DALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD-AL 530
+ ++ S P + SS K E++ P S++ +S ++ D
Sbjct: 847 SSKTKP-SRPSSQSSKK-----------EMLPPPPVSSSSQKPAKPALKRSRREADTCGQ 894
Query: 531 DKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPV 590
D + + D + P + +V+ K + G DT P L NG KP
Sbjct: 895 DPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSL-PNGNSKPG 953
Query: 591 KPPTK 595
KP K
Sbjct: 954 KPQVK 958
Score = 35.8 bits (81), Expect = 0.13
Identities = 43/193 (22%), Positives = 73/193 (37%), Gaps = 11/193 (5%)
Query: 10 KTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAG 69
K ++K++ +P + K +S+ S+D+ +K A R E + + + + + + +
Sbjct: 779 KGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSS 838
Query: 70 GESVAGITAISGKPG--DKKKEKKSLTPAVPVES---KPDKPSGKSGMDAALDDLIDTLG 124
S + + KP + KK + P PV S KP KP+ K A DT G
Sbjct: 839 SSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREA-----DTCG 893
Query: 125 GPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKP 184
+T + S P +E G R + A + P +SKP
Sbjct: 894 QDPPKSASSTKSNHKDSSIP-KQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKP 952
Query: 185 IGPDDAIDALSSD 197
P D +D
Sbjct: 953 GKPQVKFDKQQAD 965
Score = 35.0 bits (79), Expect = 0.22
Identities = 46/202 (22%), Positives = 69/202 (34%), Gaps = 41/202 (20%)
Query: 482 QNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPP----------------RDTSQSDKD 525
Q SS+ +D +L+ + QTP + APP S+S D
Sbjct: 417 QGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSD 476
Query: 526 LDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNG 585
D + D S+S D +EN+P+E E PP DN
Sbjct: 477 SDSSSDSESES---SSSDSEENEPLETPAPEPE---------------PPTTNKWQLDNW 518
Query: 586 QDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAP 645
K +P + P S D + TSQ ++ K SSSKAP
Sbjct: 519 LTKVSQPAAPPEGPRSTEPPRRHPESKGSSD-------SATSQEHSESKDPPPKSSSKAP 571
Query: 646 KNGGKAKDSAKTTEETSKPKDD 667
+ +A K + + S + +
Sbjct: 572 RAPPEAPHPGKRSCQKSPAQQE 593
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 55.5 bits (132), Expect = 2e-07
Identities = 115/564 (20%), Positives = 218/564 (38%), Gaps = 98/564 (17%)
Query: 47 AEQQPSEKSTEP-KTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPA-VPVESKPD 104
++ Q S+EP + D+ + GG+ + + +P +KK A P KP
Sbjct: 226 SDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPS 285
Query: 105 KPSGKSGMDAALDDLIDTLGG-PEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPK 163
P S + +A+ G P E+E + P++
Sbjct: 286 SPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKIC--------------------- 324
Query: 164 YRELLAKKEGITGP-PADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQ 222
R L+ K TG PA +S+ P+D +DA GS K K++++ + +
Sbjct: 325 -RNLVTPKADPTGSEPAKASEKEAPEDTVDAGEE----GSRREEAAKEPKKKASALEEGS 379
Query: 223 SAGTVRSAAPPQEKKRKVEKDTMSDQA-------------------LEALSASLG--TRQ 261
S + K+ ++ SD ++ LS LG RQ
Sbjct: 380 SDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQ 439
Query: 262 AEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-------- 313
A+ L I++ D++++ +++L+ ++ E RL P + + P
Sbjct: 440 AQQPL---GIEDKDDSQSSQDELQS----KQSKGLEERLSPPLPHEERAQSPPRSLATEE 492
Query: 314 EPEEKPKPRSESELIDELSEDFDRS-------ECKEKPSKPTE----KTEESKAAAPAP- 361
EP + P+ + E + +EL ED S + ++ PS P K + S+A P
Sbjct: 493 EPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPG 552
Query: 362 VSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKA 421
EA ++ PP ++ T P E L+++ K M++ +
Sbjct: 553 QEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALK----------AMEEAVAQV 602
Query: 422 KEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGP 481
E+D+ L E ++ R + ++++ + L + KEQ + L A+ E
Sbjct: 603 LEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE----- 657
Query: 482 QNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQ 541
+ A + E +L+ ++V S T A Q A + S + L + L+ S +R
Sbjct: 658 EEARMREEESQRLSWLRAQVQSSTQADEDQIRA---EQEASLQKLREELE--SQQKAERA 712
Query: 542 PDPDENKPMEDKVKEKAKAEHRDK 565
+N+ M +++KE+ +A + +
Sbjct: 713 SLEQKNRQMLEQLKEEIEASEKSE 736
Score = 35.8 bits (81), Expect = 0.13
Identities = 106/534 (19%), Positives = 187/534 (35%), Gaps = 97/534 (18%)
Query: 82 KPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEE-ENTTYTGPE 140
K KKKEKK + D P + ++L + LGG +T +
Sbjct: 110 KKKKKKKEKKD-------KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALR 162
Query: 141 VSDPMSSTYIEELGKR--EVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDF 198
S +S E G++ E+ +P + + A +G+ G ++ D
Sbjct: 163 GSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLG----------------SIYEDK 206
Query: 199 TCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPP-----------------QEKKRKVE 241
T S G++T +E+ E +V S++ P +E R +
Sbjct: 207 TALSLLGLGEETNEEDEEE----SDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQ 262
Query: 242 KDTMSDQALEALSASLGT--RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYR 299
+ D +L++ +A T + + P D V + + E +E SE +
Sbjct: 263 PEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPK 322
Query: 300 L-----KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEE- 353
+ P D G EP + + + + +D E R E ++P K EE
Sbjct: 323 ICRNLVTPKADPTGS----EPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEG 378
Query: 354 -SKAAAPAPVSEAVCRTSMC-SIQSAPPEPATL----KGTVPDDA--VEALADSLGKKEA 405
S A+ +SE + + SI S P L + + + V+ L+ LG
Sbjct: 379 SSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACR 438
Query: 406 DPEDGKPVMDKVKEKAKEED---REKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQL 462
+ + DK ++ +++ ++ G +E PP LP E + Q
Sbjct: 439 QAQQPLGIEDKDDSQSSQDELQSKQSKGLEERLSPP---------------LPHEERAQS 483
Query: 463 PPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQS 522
PP S L E GP+ K + + + + Q QA +PP +
Sbjct: 484 PPRS----LATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKG 539
Query: 523 DKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPE 576
+ A + LG P +E + E+KV ++ + PPE
Sbjct: 540 KEQHSQA-----EELG---PGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPE 585
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 55.1 bits (131), Expect = 2e-07
Identities = 114/561 (20%), Positives = 211/561 (37%), Gaps = 114/561 (20%)
Query: 185 IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDT 244
I P+ L DF ++ ++ E E S + S+ + EK RK E+ +
Sbjct: 174 IHPEGVASLLPPDFQ-----SSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRS 228
Query: 245 MSDQALEALSASLGTRQAEPELDL------------RSIK----EVDEAKAKEEKLEKCG 288
+ A S G++ AE E D R++K E +E + +E+ E+ G
Sbjct: 229 SRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEG 288
Query: 289 EDDETIPSEYRLKPATDKDGKPL---LPEP--EEKPKPRSESELIDELSEDFDRS----- 338
+D+ E + ++G+ + PE +E+PK RS+ + + E F RS
Sbjct: 289 DDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEAR 348
Query: 339 ------ECKEKPSKPTEKTEE--------------SKAAAPAPVSEAVCRTSMCSI---- 374
+ +EK K T EE SK+ +P ++E + S+ ++
Sbjct: 349 KSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQT 408
Query: 375 ---QSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDG--KPVMDKVKEKAKEEDREKL 429
+ PP T + + P + ++ +E +P +G PV+ ++ + D +L
Sbjct: 409 ASEEETPPPLLTKEASSPPPHPQLHSE----EEIEPMEGPAPPVLIQLSPPNTDADTREL 464
Query: 430 GEKEETI-----------PPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDF 478
+ T+ P D + E +K +P+ES LP + + L D ++
Sbjct: 465 LVSQHTVQLVGGLSPLSSPSDTKAESPAEK-----VPEES--VLPLVQKSTLADYSAQKD 517
Query: 479 SGPQNASS-----LKFEDAKLAAAISEVVSQTPASTTQAGAPPRDT--------SQSDKD 525
P++ S LK E+ LA I+E + P+ + G T +D
Sbjct: 518 LEPESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSS 577
Query: 526 LDDALDKLSDSLGQRQPDPD-----ENKPMEDKVKEKAKA------EHRDKLGER---DD 571
+ S S R PD + P+ K ++ A+A R K+G R +
Sbjct: 578 SSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSES 637
Query: 572 TIPPEYRHLLDDNGQDKPVKPPTKKSE-----DSKKPADDQDPIDALSGDLDSCPSTTET 626
R + K + P + ++K P+ Q+ L C T
Sbjct: 638 RSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVATPPVPQLQVCEPKERT 697
Query: 627 SQNTAKDKCKKAASSSKAPKN 647
S +++ + ++ + A K+
Sbjct: 698 STSSSSVQARRLSQPESAEKH 718
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 54.7 bits (130), Expect = 3e-07
Identities = 104/669 (15%), Positives = 219/669 (32%), Gaps = 18/669 (2%)
Query: 7 KAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMI 66
K + S + S +SD+ S+D+ N + S S++ S+ S + +
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS-NSSSDSDSSDSDSSDSSDSDSSDSSNSS 602
Query: 67 SAGGESVAGITAISGKPGDKKKE-KKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGG 125
+ S + ++ S D K + KS + + +SK D S + D D+
Sbjct: 603 DSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNS 662
Query: 126 PEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPI 185
++ +++ + S SS + + + + + + + +DSS
Sbjct: 663 SNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSN 722
Query: 186 GPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTM 245
D D+ +S + S ++ + S + S+ + S+ D+
Sbjct: 723 SSDS--DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 780
Query: 246 -SDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPAT 304
S + ++ ++S + + S D + + + + + S +
Sbjct: 781 NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSD 840
Query: 305 DKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSE 364
D + RS+S + S+ D S + S ++ E S ++ + S
Sbjct: 841 SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS-SDSSDSNESSNSSDSSDSSN 899
Query: 365 AVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEE 424
+ S S S+ ++ D+ E+ S +D + D +
Sbjct: 900 SSDSDSSDSSNSSDSSDSSNS----SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 955
Query: 425 DREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNA 484
+ D + D S S D + S D S ++
Sbjct: 956 SSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015
Query: 485 S----SLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQS--DKDLDDALDKLSDSLG 538
S S D+ ++ S+ + +S + + D+S S D D+ D S
Sbjct: 1016 SNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1075
Query: 539 QRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLD-DNGQDKPVKPPTKKS 597
D E+ D ++ D D + + D N D + S
Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1135
Query: 598 EDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKT 657
DS +D D ++ S DS S+ + + + D + SS+ + + +
Sbjct: 1136 SDSSNSSDSSDSSES-SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1194
Query: 658 TEETSKPKD 666
+ ++S D
Sbjct: 1195 SSDSSDSSD 1203
Score = 50.1 bits (118), Expect = 7e-06
Identities = 90/657 (13%), Positives = 205/657 (31%), Gaps = 24/657 (3%)
Query: 11 TEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGG 70
++ S S+ + + S+D+ N S S++ S+ S + + S
Sbjct: 669 SDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS-SDSD 727
Query: 71 ESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETE 130
S + ++ S D S + +S S S + D D+ + +
Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND 787
Query: 131 EENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDA 190
N++ + + SS + + + + + + +DSS D+
Sbjct: 788 SSNSSDSSDSSNSSDSSNSSDSSDSSDSS------DSDSSNSSDSSNSSDSSDSSNSSDS 841
Query: 191 IDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQAL 250
D SSD + GS + + +++ S++ + + ++ + SD +
Sbjct: 842 SD--SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN 899
Query: 251 EALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKP 310
+ S S + + D + + E+ + + + ++D
Sbjct: 900 SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS--------DSSDSSDSS 951
Query: 311 LLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTS 370
+ + S+ D S D S S ++ ++ S ++ + S++ +
Sbjct: 952 NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011
Query: 371 MCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLG 430
++ + + D+ ++ S +D D + + +
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071
Query: 431 EKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFE 490
+ + D E D S S D + S D S N+S
Sbjct: 1072 SSDSSDSSDS--SESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1129
Query: 491 DAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPM 550
++ S S + S+ + + S D D+ D S D ++
Sbjct: 1130 SDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1189
Query: 551 EDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPI 610
D ++ D D + + + D + S +S +D D
Sbjct: 1190 SDSSDSSDSSDSSDSSDSSDSSDSSD-----SSDSSDSSDSSDSSDSNESSDSSDSSDSS 1244
Query: 611 DALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 667
D+ + S S + S + + D+ + S NG + ++ ++ DD
Sbjct: 1245 DSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 48.1 bits (113), Expect = 3e-05
Identities = 93/672 (13%), Positives = 215/672 (31%), Gaps = 33/672 (4%)
Query: 4 TETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQ 63
+++ + K+E + +K S +SD+ N + + S ++ + +
Sbjct: 622 SKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSS 681
Query: 64 DMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTL 123
D ++ S + ++ S + D S + S + S + D ++
Sbjct: 682 DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS 741
Query: 124 GGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSK 183
+ ++ N++ + SD +S+ + + + +DS+
Sbjct: 742 DSSDSSDSSNSS-DSSDSSDSSNSSDSSDSSD-------------SSDSSDSSNSSDSND 787
Query: 184 PIGPDDAIDAL-SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEK 242
D+ D+ SSD + S ++ + +S+ + ++ ++ + +
Sbjct: 788 SSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS 847
Query: 243 DTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKP 302
SD S S + + D + + ++ E D +
Sbjct: 848 SDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS--------N 899
Query: 303 ATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPV 362
++D D + S S D S S ++ ++ S ++ +
Sbjct: 900 SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959
Query: 363 SEAVCRTSMCSIQSAPPEPATLKGTVPD--DAVEALADSLGKKEADPEDGKPVMDKVKEK 420
S++ + S+ ++ D D+ ++ S +D D D
Sbjct: 960 SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019
Query: 421 AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG 480
+ + + D + D + S+ S+
Sbjct: 1020 DSSNSSDSSNSSDSSDSSD-SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1078
Query: 481 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQS--DKDLDDALDKLSDSLG 538
++ S D+ ++ S+ + +S + + D+S S D D+ D S
Sbjct: 1079 SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1138
Query: 539 QRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLD-DNGQDKPVKPPTKKS 597
D ++ D ++ D D + + + D + D + S
Sbjct: 1139 SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1198
Query: 598 EDSKKPADDQDPIDA--LSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSA 655
DS +D D D+ S DS S+ + N + D + SS + N + DS+
Sbjct: 1199 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSS--NSSDSSDSS 1256
Query: 656 KTTEETSKPKDD 667
+++ TS D+
Sbjct: 1257 DSSDSTSDSNDE 1268
Score = 36.6 bits (83), Expect = 0.077
Identities = 67/473 (14%), Positives = 162/473 (34%), Gaps = 22/473 (4%)
Query: 195 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKR--KVEKDTMSDQALEA 252
S D GS + + + + +++ + S G + +K K + D+ + ++
Sbjct: 498 SKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS 557
Query: 253 LSASLGTRQAEPEL-DLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPL 311
++S + ++ + D S + D + + D + S+ ++D
Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD-----SSDSSDSSD 612
Query: 312 LPEPEEKPKPRSESELIDELSEDFD-RSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTS 370
+ + +S+S + S D D +S+ + S + +S ++ + S +S
Sbjct: 613 SSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSS 672
Query: 371 MCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLG 430
S S+ + + + ++S ++ D D + + D
Sbjct: 673 DSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS 732
Query: 431 EKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFE 490
+ ++ + D S S D + S D S N+S
Sbjct: 733 DSSDSS----NSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN-- 786
Query: 491 DAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPM 550
D+ ++ S+ + + +S + + D+S SD SDS +
Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD 846
Query: 551 EDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPI 610
+ + D D + + N D + +S +S +D +
Sbjct: 847 SSDGSDSDSSNRSDSSNSSDSSDSSD-----SSNSSDSSDSSDSNESSNSSDSSDSSNSS 901
Query: 611 DALSGDLDSCPSTTETSQNTAKDKCKKAA--SSSKAPKNGGKAKDSAKTTEET 661
D+ S D + ++++S ++ + ++ S+S N + DS+ ++ +
Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954
Score = 33.5 bits (75), Expect = 0.65
Identities = 32/146 (21%), Positives = 55/146 (37%), Gaps = 11/146 (7%)
Query: 518 DTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEY 577
D S + D + D S S G + DE+K + K E DD+
Sbjct: 469 DESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKG--------AEDDDSDSTSD 520
Query: 578 RHLLDDNGQDKPVKPPTKKSEDSKKPAD--DQDPIDALSGDLDSCPSTTETSQNTAKDKC 635
+ D NG KS+ K +D D D D+ S DS S+ S ++
Sbjct: 521 TNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS-SNSSDSSDSSDSDSSDSNSSSD 579
Query: 636 KKAASSSKAPKNGGKAKDSAKTTEET 661
++ S + + + DS+ +++ +
Sbjct: 580 SDSSDSDSSDSSDSDSSDSSNSSDSS 605
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 53.9 bits (128), Expect = 5e-07
Identities = 142/706 (20%), Positives = 238/706 (33%), Gaps = 108/706 (15%)
Query: 8 AVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMIS 67
AV+ + EK +++ +++SD S D+ A +A+ +P+ K + K P+ +
Sbjct: 596 AVQVKAEKPMDNSESS---EESSD--SADSEEAPAAMTAAQAKPALKIPQTKACPKKTNT 650
Query: 68 AGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPE 127
VA + + P +K+ T P S P G D+ E
Sbjct: 651 TASAKVAPVRVGTQAP------RKAGTATSPAGSSPAVAGGTQRPAE------DSSSSEE 698
Query: 128 ETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPK------YRELLAKKEGITGPPADS 181
EE T G V+ + + + L + ++P K +L K G T +
Sbjct: 699 SDSEEEKT--GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKA 756
Query: 182 SKPIGPDDAIDALSSDFTCGSPT---AAGKKTEKEESTEVLKAQSA-GTVRS-----AAP 232
K + + + S+ SP + KKT+ + + +A SA GT+ + A
Sbjct: 757 EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAA 816
Query: 233 PQEKKR---KVEKDTMSDQALEALS-------------ASLGTRQAEPELDLRSIKEVDE 276
Q K+R KV+ + Q L+ A+ Q PE D S +E +
Sbjct: 817 AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESD 876
Query: 277 AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFD 336
++ + E L + +T L PA + K P P K P +
Sbjct: 877 SEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQA---------- 926
Query: 337 RSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEAL 396
K+ S + + +S APA V+ A Q P P A A
Sbjct: 927 ---GKQDDSGSSSEESDSDGEAPAAVTSA---------QVIKP-PLIFVDPNRSPAGPAA 973
Query: 397 ADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKP-LLP 455
+ + + P + + + E + E + + + P R V P + P
Sbjct: 974 TPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAP 1033
Query: 456 KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAP 515
K S E +S+ A+ + L A + S T + P
Sbjct: 1034 KASMAGASSSKES---SRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKP 1090
Query: 516 P----RDTSQSDKDLDDALDKLSDSLGQRQPD--PDENKPMEDKV-----KEKAKAEHRD 564
+ +++ + DD+ D S G + P K V + + E
Sbjct: 1091 KLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETA 1150
Query: 565 KLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTT 624
DD + P L +G P P P LDS PS +
Sbjct: 1151 AESSEDDVVAPSQSLL---SGYMTPGLTPANSQASKATPK------------LDSSPSVS 1195
Query: 625 ET----SQNTAKDKCK-KAASSSKAPKNGGKAKDSAKTTEETSKPK 665
T K + K + A+ +PK GGK S T +++ KPK
Sbjct: 1196 STLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK 1241
Score = 53.5 bits (127), Expect = 6e-07
Identities = 143/683 (20%), Positives = 226/683 (33%), Gaps = 108/683 (15%)
Query: 49 QQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSG 108
QQ SE + K + + A V+ + S + E++ A ++ P S
Sbjct: 54 QQTSELGRKRKAEEDAALQAKKTRVSDPISTS-----ESSEEEEEAEAETAKATPRLAST 108
Query: 109 KSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEEL--GK--REVTIPPKY 164
S + A DL ++ + E E TG + P + + L GK R+ P
Sbjct: 109 NSSVLGA--DLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
Query: 165 RELLAKKEGITGPPA--DSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQ 222
L+++ E PA ++KP + A +D + +++ +T+ E V AQ
Sbjct: 167 TTLVSETEEEGSVPAFGAAAKP----GMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQ 222
Query: 223 SAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASL--GTRQAEPELDLRSIKEVDEAKAK 280
+ S +K + D + +L R +PE + S +E E+
Sbjct: 223 VKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSES--- 279
Query: 281 EEKLEKCGEDDETIPSEYRLK------PATDKDGKPLLPEPEEKPKPRSESELIDELSED 334
E+ G + SE L+ PA GK P P K + + ED
Sbjct: 280 -EEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEED 338
Query: 335 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 394
+ S E+ S E+T +KA A S +TS SAP + + KG P
Sbjct: 339 SESSS--EESSDSEEETPAAKALLQAKASG---KTSQVGAASAPAKESPRKGAAP----- 388
Query: 395 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEK---EETIP---------PDYRL 442
A P P + K + +EED + E+ EE P P R
Sbjct: 389 ----------APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRA 438
Query: 443 EEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVV 502
K+ P++ PP + + SS + D+ A +
Sbjct: 439 ASAPAKES----PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNA 494
Query: 503 SQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEH 562
+Q P T A +G P K ED E + E
Sbjct: 495 AQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEED--SESSSEES 552
Query: 563 RDKL-GERDDTIPPEYRHLLDDNGQDKPVKPPTK-----------------------KSE 598
D GE + P L + Q KP P K SE
Sbjct: 553 SDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSE 612
Query: 599 DSKKPADDQDPIDALSG----------DLDSCPSTTETSQNTAKDKCKKAASSSKAPKNG 648
+S AD ++ A++ +CP T T TA K ++AP+
Sbjct: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNT---TASAKVAPVRVGTQAPRKA 669
Query: 649 GKAKDSAKTTEE----TSKPKDD 667
G A A ++ T +P +D
Sbjct: 670 GTATSPAGSSPAVAGGTQRPAED 692
Score = 33.9 bits (76), Expect = 0.50
Identities = 132/708 (18%), Positives = 243/708 (34%), Gaps = 75/708 (10%)
Query: 20 TKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 79
T+ K+ ++ S++ ++ +++A + A+ + S K T+ K P +A S G +
Sbjct: 752 TQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA---AARAPSAKGTISA 808
Query: 80 SGKPGDKKKEKKSLTPAV---PVESKPDK------PSGKSGMDAALDDLIDTLGGPEE-- 128
GK + K +P+ PV + + P+ + A+ GPEE
Sbjct: 809 PGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 868
Query: 129 --TEEENTTYTGPEVS---DPMSSTYI---------EELGKREVTIPPKYRELLAKKEGI 174
+EEE+ + E P T+ E K PP A + G
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGK 928
Query: 175 TGPPADSSKPIGPD-DAIDALSSDFTCGSPT--AAGKKTEKEESTEVLKAQSAGTVRSAA 231
SS+ D +A A++S P ++ + +AQ+A T R A
Sbjct: 929 QDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKAR 988
Query: 232 PPQEKKRKVEKDTMSDQALEA---LSASLGTR-----QAEPELDLR-------SIKE--- 273
+ R ++ + + A L+ + T A P + + S KE
Sbjct: 989 ASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSR 1048
Query: 274 VDEAKAKEEKLEKCGEDDETIPSEYRLKPA-----TDKDGKPLLPEPEEKPKPRSESELI 328
+ + K +E + T+P+ + T+K KP LPE ++ K S+
Sbjct: 1049 ISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDS 1108
Query: 329 DELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQS--APPEPATLKG 386
++ S+ SE + + + P+ V T+ S + P + L G
Sbjct: 1109 EDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSG 1168
Query: 387 TVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET---IPPDYRLE 443
+ A +S K D P + + D ++ + ++ + P +
Sbjct: 1169 YMTPGLTPA--NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGK 1226
Query: 444 EVKDKDGKPLLPKESKEQLPPMSEDFLLDA-LSEDFSG---PQNASSLKFEDAKLAAAIS 499
E K K P + L + +++ G P N + ++ K+ +
Sbjct: 1227 EAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELL 1286
Query: 500 EVVSQTPASTTQAGAPPRDTSQSDKDLDDA------LDKLSDSLGQRQPDPDENKPMEDK 553
E + TT+ + S+ K D K LG + P +
Sbjct: 1287 EQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTS 1346
Query: 554 VKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDAL 613
K KA+ RDK D + + L G + +K + + D +P +
Sbjct: 1347 TTSKGKAK-RDKAS--GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNP-KSK 1402
Query: 614 SGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEET 661
S + + K K KKA++ + K K KT E+T
Sbjct: 1403 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1450
Score = 30.0 bits (66), Expect = 7.2
Identities = 26/97 (26%), Positives = 35/97 (36%), Gaps = 13/97 (13%)
Query: 13 PEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGES 72
PEK S ++K K+ D S D KK Q ++ E K + G +S
Sbjct: 1342 PEKTSTTSKGKA----KRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQS 1397
Query: 73 VAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGK 109
P KK++KKS E K K K
Sbjct: 1398 ---------NPKSKKEKKKSDKRKKDKEKKEKKKKAK 1425
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.299 0.121 0.328
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,729,869
Number of Sequences: 37866
Number of extensions: 1724267
Number of successful extensions: 11535
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 97
Number of HSP's successfully gapped in prelim test: 862
Number of HSP's that attempted gapping in prelim test: 7753
Number of HSP's gapped (non-prelim): 3263
length of query: 667
length of database: 18,247,518
effective HSP length: 109
effective length of query: 558
effective length of database: 14,120,124
effective search space: 7879029192
effective search space used: 7879029192
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.