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Search of human proteins with 109637759
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109637759 calpastatin isoform f [Homo sapiens]
(750 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109637759 calpastatin isoform f [Homo sapiens] 1478 0.0
gi|109637763 calpastatin isoform h [Homo sapiens] 1467 0.0
gi|109637761 calpastatin isoform g [Homo sapiens] 1466 0.0
gi|109637753 calpastatin isoform a [Homo sapiens] 1454 0.0
gi|109637757 calpastatin isoform e [Homo sapiens] 1431 0.0
gi|109637767 calpastatin isoform j [Homo sapiens] 1321 0.0
gi|27765085 calpastatin isoform b [Homo sapiens] 1310 0.0
gi|109637765 calpastatin isoform i [Homo sapiens] 1297 0.0
gi|109637771 calpastatin isoform l [Homo sapiens] 1286 0.0
gi|109637769 calpastatin isoform k [Homo sapiens] 1274 0.0
gi|27765087 calpastatin isoform c [Homo sapiens] 781 0.0
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 91 3e-18
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 68 3e-11
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 67 5e-11
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 67 6e-11
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 67 6e-11
gi|104526627 triadin [Homo sapiens] 66 1e-10
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 65 2e-10
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 65 2e-10
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 65 2e-10
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 65 2e-10
gi|150170670 piccolo isoform 2 [Homo sapiens] 65 2e-10
gi|150378539 piccolo isoform 1 [Homo sapiens] 65 2e-10
gi|42518068 trans-golgi network protein 2 [Homo sapiens] 62 1e-09
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 62 2e-09
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 62 3e-09
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 62 3e-09
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 61 3e-09
gi|109637791 transcription factor-like nuclear regulator [Homo s... 61 3e-09
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 61 4e-09
>gi|109637759 calpastatin isoform f [Homo sapiens]
Length = 750
Score = 1478 bits (3827), Expect = 0.0
Identities = 750/750 (100%), Positives = 750/750 (100%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDA 120
YAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDA
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDA 120
Query: 121 HNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAV 180
HNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAV
Sbjct: 121 HNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAV 180
Query: 181 PVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKRE 240
PVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKRE
Sbjct: 181 PVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKRE 240
Query: 241 VTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTE 300
VTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTE
Sbjct: 241 VTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTE 300
Query: 301 VLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEA 360
VLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEA
Sbjct: 301 VLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEA 360
Query: 361 KAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR 420
KAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR
Sbjct: 361 KAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR 420
Query: 421 SECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALA 480
SECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALA
Sbjct: 421 SECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALA 480
Query: 481 DSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKE 540
DSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKE
Sbjct: 481 DSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKE 540
Query: 541 SKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPR 600
SKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPR
Sbjct: 541 SKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPR 600
Query: 601 DTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEY 660
DTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEY
Sbjct: 601 DTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEY 660
Query: 661 RHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKK 720
RHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKK
Sbjct: 661 RHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKK 720
Query: 721 AASSSKAPKNGGKAKDSAKTTEETSKPKDD 750
AASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 721 AASSSKAPKNGGKAKDSAKTTEETSKPKDD 750
>gi|109637763 calpastatin isoform h [Homo sapiens]
Length = 769
Score = 1467 bits (3797), Expect = 0.0
Identities = 750/769 (97%), Positives = 750/769 (97%), Gaps = 19/769 (2%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTK---------------- 104
YAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTK
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKE 120
Query: 105 ---PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA 161
PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA
Sbjct: 121 HTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA 180
Query: 162 ISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTG 221
ISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTG
Sbjct: 181 ISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTG 240
Query: 222 PEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDF 281
PEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDF
Sbjct: 241 PEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDF 300
Query: 282 TCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLG 341
TCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLG
Sbjct: 301 TCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLG 360
Query: 342 TRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEK 401
TRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEK
Sbjct: 361 TRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEK 420
Query: 402 PKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAP 461
PKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAP
Sbjct: 421 PKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAP 480
Query: 462 PEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 521
PEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP
Sbjct: 481 PEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 540
Query: 522 DYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAI 581
DYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAI
Sbjct: 541 DYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAI 600
Query: 582 SEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKA 641
SEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKA
Sbjct: 601 SEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKA 660
Query: 642 KAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLD 701
KAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLD
Sbjct: 661 KAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLD 720
Query: 702 SCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 750
SCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 721 SCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 769
>gi|109637761 calpastatin isoform g [Homo sapiens]
Length = 772
Score = 1466 bits (3794), Expect = 0.0
Identities = 750/772 (97%), Positives = 750/772 (97%), Gaps = 22/772 (2%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKA----------------------VKTEPEK 98
YAGGTASATKVSASSGATSKSSSMNPTETKA VKTEPEK
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEK 120
Query: 99 KSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAG 158
KSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAG
Sbjct: 121 KSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAG 180
Query: 159 ITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTT 218
ITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTT
Sbjct: 181 ITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTT 240
Query: 219 YTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALS 278
YTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALS
Sbjct: 241 YTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALS 300
Query: 279 SDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSA 338
SDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSA
Sbjct: 301 SDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSA 360
Query: 339 SLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEP 398
SLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEP
Sbjct: 361 SLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEP 420
Query: 399 EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ 458
EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ
Sbjct: 421 EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ 480
Query: 459 SAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET 518
SAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET
Sbjct: 481 SAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET 540
Query: 519 IPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLA 578
IPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLA
Sbjct: 541 IPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLA 600
Query: 579 AAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVK 638
AAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVK
Sbjct: 601 AAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVK 660
Query: 639 EKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSG 698
EKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSG
Sbjct: 661 EKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSG 720
Query: 699 DLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 750
DLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 721 DLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 772
>gi|109637753 calpastatin isoform a [Homo sapiens]
Length = 791
Score = 1454 bits (3764), Expect = 0.0
Identities = 750/791 (94%), Positives = 750/791 (94%), Gaps = 41/791 (5%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKA----------------------VKTEPEK 98
YAGGTASATKVSASSGATSKSSSMNPTETKA VKTEPEK
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEK 120
Query: 99 KSQSTK-------------------PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 139
KSQSTK PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST
Sbjct: 121 KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 180
Query: 140 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 199
EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL
Sbjct: 181 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 240
Query: 200 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG 259
DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG
Sbjct: 241 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG 300
Query: 260 PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 319
PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK
Sbjct: 301 PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 360
Query: 320 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS 379
KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS
Sbjct: 361 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS 420
Query: 380 EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 439
EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA
Sbjct: 421 EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 480
Query: 440 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 499
AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK
Sbjct: 481 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 540
Query: 500 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 559
VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE
Sbjct: 541 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 600
Query: 560 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS 619
DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS
Sbjct: 601 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS 660
Query: 620 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK 679
LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK
Sbjct: 661 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK 720
Query: 680 SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK 739
SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK
Sbjct: 721 SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK 780
Query: 740 TTEETSKPKDD 750
TTEETSKPKDD
Sbjct: 781 TTEETSKPKDD 791
>gi|109637757 calpastatin isoform e [Homo sapiens]
Length = 756
Score = 1431 bits (3705), Expect = 0.0
Identities = 737/769 (95%), Positives = 737/769 (95%), Gaps = 32/769 (4%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTK---------------- 104
YAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTK
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKE 120
Query: 105 ---PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA 161
PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA
Sbjct: 121 HTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA 180
Query: 162 ISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTG 221
ISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTG
Sbjct: 181 ISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTG 240
Query: 222 PEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDF 281
PEVSDPMSSTYIEELGKREVTIPPKYRELLAK PIGPDDAIDALSSDF
Sbjct: 241 PEVSDPMSSTYIEELGKREVTIPPKYRELLAK-------------PIGPDDAIDALSSDF 287
Query: 282 TCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLG 341
TCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLG
Sbjct: 288 TCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLG 347
Query: 342 TRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEK 401
TRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEK
Sbjct: 348 TRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEK 407
Query: 402 PKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAP 461
PKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAP
Sbjct: 408 PKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAP 467
Query: 462 PEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 521
PEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP
Sbjct: 468 PEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 527
Query: 522 DYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAI 581
DYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAI
Sbjct: 528 DYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAI 587
Query: 582 SEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKA 641
SEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKA
Sbjct: 588 SEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKA 647
Query: 642 KAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLD 701
KAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLD
Sbjct: 648 KAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLD 707
Query: 702 SCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 750
SCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 708 SCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 756
>gi|109637767 calpastatin isoform j [Homo sapiens]
Length = 667
Score = 1321 bits (3420), Expect = 0.0
Identities = 667/667 (100%), Positives = 667/667 (100%)
Query: 84 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 143
MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT
Sbjct: 1 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
Query: 144 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI 203
KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI
Sbjct: 61 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI 120
Query: 204 DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPAD 263
DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPAD
Sbjct: 121 DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPAD 180
Query: 264 SSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV 323
SSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV
Sbjct: 181 SSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV 240
Query: 324 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 383
EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL
Sbjct: 241 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 300
Query: 384 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA 443
KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA
Sbjct: 301 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA 360
Query: 444 PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK 503
PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK
Sbjct: 361 PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK 420
Query: 504 AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG 563
AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG
Sbjct: 421 AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG 480
Query: 564 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR 623
PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR
Sbjct: 481 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR 540
Query: 624 QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS 683
QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS
Sbjct: 541 QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS 600
Query: 684 KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 743
KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE
Sbjct: 601 KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 660
Query: 744 TSKPKDD 750
TSKPKDD
Sbjct: 661 TSKPKDD 667
Score = 221 bits (564), Expect = 1e-57
Identities = 188/642 (29%), Positives = 305/642 (47%), Gaps = 60/642 (9%)
Query: 16 RAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASL----GSSQSSRTYAGGTASATKV 71
+ A +R + SEK++E +KP + + + A + G + A V
Sbjct: 40 KKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPV 99
Query: 72 SASSGATSKSSSMNPTETKAVKT--EPEKKSQSTKPKSLPKQASDTGSN----------- 118
+ S S M+ + T PE+ + + P+ + S
Sbjct: 100 ESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVT 159
Query: 119 --DAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISA-GGESVAGITAISGKPGDKKKEKK- 174
+ + + P S++P P D I A + G +GK +K++ +
Sbjct: 160 IPPKYRELLAKKEGITGPPADSSKP-IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEV 218
Query: 175 -------SLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDP 227
++ A P + K K + D AL+ L +L G + E E + EV +
Sbjct: 219 LKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASL-GTRQAEPELDLRSIKEVDEA 277
Query: 228 MS-STYIEELGKREVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDALSSDFTC 283
+ +E+ G+ + TIP +YR + K+G + P + KP + ID LS DF
Sbjct: 278 KAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR 337
Query: 284 G----SPTAAGKKTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQAL 333
P+ +KTE+ ++ +E + S +++SA P + K T+ D A+
Sbjct: 338 SECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDAV 393
Query: 334 EALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKP 393
EAL+ SLG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKP
Sbjct: 394 EALADSLGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKP 452
Query: 394 LLP-EPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 452
LLP E +E+ P SE L+D LSEDF + + + K E++K A A +SE V +T
Sbjct: 453 LLPKESKEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQT 505
Query: 453 SMCSIQS-APPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREK 511
+ Q+ APP + DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+K
Sbjct: 506 PASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDK 565
Query: 512 LGEKEETIPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASS 569
LGE+++TIPP+YR + KP+ P K+S++ P + +DALS D + +
Sbjct: 566 LGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTE 625
Query: 570 LKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 611
AK + S+ P + +A + T ++ K DD
Sbjct: 626 TSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 667
Score = 79.7 bits (195), Expect = 9e-15
Identities = 88/362 (24%), Positives = 152/362 (41%), Gaps = 42/362 (11%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAA---------- 50
+ +P +KP PR + + + E PSKP EK ++E KAA
Sbjct: 312 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEK--TEESKAAAPAPVSEAVC 367
Query: 51 -----SLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQ---- 101
S+ S+ GT V A + + K + +P + K V + ++K++
Sbjct: 368 RTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEA-DPEDGKPVMDKVKEKAKEEDR 426
Query: 102 ---STKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAG 158
K +++P D K + + +++Q S + +G ++ +
Sbjct: 427 EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASS 486
Query: 159 ITAISGKPGDKKKEKKSLTPAVPVES-KPDKPSGKS--GMDAALDDLIDTLGGPEETEEE 215
+ K E S TPA ++ P + + +S +D ALD L D+LG + +E
Sbjct: 487 LKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDE 546
Query: 216 NTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITGPPA----DSSKPIG 269
N +V + + + ++LG+R+ TIPP+YR LL ++ PP DS KP
Sbjct: 547 NKPME-DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPAD 605
Query: 270 PDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRKVE 324
D IDALS D +C S T + T K++ + + A G + +A E+ K +
Sbjct: 606 DQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPK 665
Query: 325 KD 326
D
Sbjct: 666 DD 667
>gi|27765085 calpastatin isoform b [Homo sapiens]
Length = 686
Score = 1310 bits (3390), Expect = 0.0
Identities = 667/686 (97%), Positives = 667/686 (97%), Gaps = 19/686 (2%)
Query: 84 MNPTETKAVKTEPEKKSQSTK-------------------PKSLPKQASDTGSNDAHNKK 124
MNPTETKAVKTEPEKKSQSTK PKSLPKQASDTGSNDAHNKK
Sbjct: 1 MNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKK 60
Query: 125 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 184
AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES
Sbjct: 61 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 120
Query: 185 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 244
KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP
Sbjct: 121 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 180
Query: 245 PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 304
PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA
Sbjct: 181 PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 240
Query: 305 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 364
QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE
Sbjct: 241 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 300
Query: 365 EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK 424
EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK
Sbjct: 301 EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK 360
Query: 425 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 484
EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG
Sbjct: 361 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 420
Query: 485 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 544
KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ
Sbjct: 421 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 480
Query: 545 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 604
LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ
Sbjct: 481 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 540
Query: 605 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 664
SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL
Sbjct: 541 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 600
Query: 665 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 724
DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS
Sbjct: 601 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 660
Query: 725 SKAPKNGGKAKDSAKTTEETSKPKDD 750
SKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 661 SKAPKNGGKAKDSAKTTEETSKPKDD 686
Score = 221 bits (564), Expect = 1e-57
Identities = 188/642 (29%), Positives = 305/642 (47%), Gaps = 60/642 (9%)
Query: 16 RAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASL----GSSQSSRTYAGGTASATKV 71
+ A +R + SEK++E +KP + + + A + G + A V
Sbjct: 59 KKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPV 118
Query: 72 SASSGATSKSSSMNPTETKAVKT--EPEKKSQSTKPKSLPKQASDTGSN----------- 118
+ S S M+ + T PE+ + + P+ + S
Sbjct: 119 ESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVT 178
Query: 119 --DAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISA-GGESVAGITAISGKPGDKKKEKK- 174
+ + + P S++P P D I A + G +GK +K++ +
Sbjct: 179 IPPKYRELLAKKEGITGPPADSSKP-IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEV 237
Query: 175 -------SLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDP 227
++ A P + K K + D AL+ L +L G + E E + EV +
Sbjct: 238 LKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASL-GTRQAEPELDLRSIKEVDEA 296
Query: 228 MS-STYIEELGKREVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDALSSDFTC 283
+ +E+ G+ + TIP +YR + K+G + P + KP + ID LS DF
Sbjct: 297 KAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR 356
Query: 284 G----SPTAAGKKTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQAL 333
P+ +KTE+ ++ +E + S +++SA P + K T+ D A+
Sbjct: 357 SECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDAV 412
Query: 334 EALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKP 393
EAL+ SLG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKP
Sbjct: 413 EALADSLGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKP 471
Query: 394 LLP-EPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 452
LLP E +E+ P SE L+D LSEDF + + + K E++K A A +SE V +T
Sbjct: 472 LLPKESKEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQT 524
Query: 453 SMCSIQS-APPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREK 511
+ Q+ APP + DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+K
Sbjct: 525 PASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDK 584
Query: 512 LGEKEETIPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASS 569
LGE+++TIPP+YR + KP+ P K+S++ P + +DALS D + +
Sbjct: 585 LGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTE 644
Query: 570 LKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 611
AK + S+ P + +A + T ++ K DD
Sbjct: 645 TSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 686
Score = 79.7 bits (195), Expect = 9e-15
Identities = 88/362 (24%), Positives = 152/362 (41%), Gaps = 42/362 (11%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAA---------- 50
+ +P +KP PR + + + E PSKP EK ++E KAA
Sbjct: 331 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEK--TEESKAAAPAPVSEAVC 386
Query: 51 -----SLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQ---- 101
S+ S+ GT V A + + K + +P + K V + ++K++
Sbjct: 387 RTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEA-DPEDGKPVMDKVKEKAKEEDR 445
Query: 102 ---STKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAG 158
K +++P D K + + +++Q S + +G ++ +
Sbjct: 446 EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASS 505
Query: 159 ITAISGKPGDKKKEKKSLTPAVPVES-KPDKPSGKS--GMDAALDDLIDTLGGPEETEEE 215
+ K E S TPA ++ P + + +S +D ALD L D+LG + +E
Sbjct: 506 LKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDE 565
Query: 216 NTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITGPPA----DSSKPIG 269
N +V + + + ++LG+R+ TIPP+YR LL ++ PP DS KP
Sbjct: 566 NKPME-DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPAD 624
Query: 270 PDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRKVE 324
D IDALS D +C S T + T K++ + + A G + +A E+ K +
Sbjct: 625 DQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPK 684
Query: 325 KD 326
D
Sbjct: 685 DD 686
>gi|109637765 calpastatin isoform i [Homo sapiens]
Length = 708
Score = 1297 bits (3357), Expect = 0.0
Identities = 667/708 (94%), Positives = 667/708 (94%), Gaps = 41/708 (5%)
Query: 84 MNPTETKA----------------------VKTEPEKKSQSTK----------------- 104
MNPTETKA VKTEPEKKSQSTK
Sbjct: 1 MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEH 60
Query: 105 --PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 162
PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI
Sbjct: 61 TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 120
Query: 163 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 222
SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP
Sbjct: 121 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 180
Query: 223 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 282
EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT
Sbjct: 181 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 240
Query: 283 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 342
CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT
Sbjct: 241 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 300
Query: 343 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 402
RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP
Sbjct: 301 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 360
Query: 403 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 462
KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP
Sbjct: 361 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 420
Query: 463 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 522
EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD
Sbjct: 421 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 480
Query: 523 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 582
YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS
Sbjct: 481 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 540
Query: 583 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 642
EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK
Sbjct: 541 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 600
Query: 643 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 702
AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS
Sbjct: 601 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 660
Query: 703 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 750
CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 661 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 708
Score = 221 bits (564), Expect = 1e-57
Identities = 188/642 (29%), Positives = 305/642 (47%), Gaps = 60/642 (9%)
Query: 16 RAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASL----GSSQSSRTYAGGTASATKV 71
+ A +R + SEK++E +KP + + + A + G + A V
Sbjct: 81 KKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPV 140
Query: 72 SASSGATSKSSSMNPTETKAVKT--EPEKKSQSTKPKSLPKQASDTGSN----------- 118
+ S S M+ + T PE+ + + P+ + S
Sbjct: 141 ESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVT 200
Query: 119 --DAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISA-GGESVAGITAISGKPGDKKKEKK- 174
+ + + P S++P P D I A + G +GK +K++ +
Sbjct: 201 IPPKYRELLAKKEGITGPPADSSKP-IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEV 259
Query: 175 -------SLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDP 227
++ A P + K K + D AL+ L +L G + E E + EV +
Sbjct: 260 LKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASL-GTRQAEPELDLRSIKEVDEA 318
Query: 228 MS-STYIEELGKREVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDALSSDFTC 283
+ +E+ G+ + TIP +YR + K+G + P + KP + ID LS DF
Sbjct: 319 KAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR 378
Query: 284 G----SPTAAGKKTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQAL 333
P+ +KTE+ ++ +E + S +++SA P + K T+ D A+
Sbjct: 379 SECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDAV 434
Query: 334 EALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKP 393
EAL+ SLG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKP
Sbjct: 435 EALADSLGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKP 493
Query: 394 LLP-EPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 452
LLP E +E+ P SE L+D LSEDF + + + K E++K A A +SE V +T
Sbjct: 494 LLPKESKEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQT 546
Query: 453 SMCSIQS-APPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREK 511
+ Q+ APP + DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+K
Sbjct: 547 PASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDK 606
Query: 512 LGEKEETIPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASS 569
LGE+++TIPP+YR + KP+ P K+S++ P + +DALS D + +
Sbjct: 607 LGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTE 666
Query: 570 LKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 611
AK + S+ P + +A + T ++ K DD
Sbjct: 667 TSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 708
Score = 79.7 bits (195), Expect = 9e-15
Identities = 88/362 (24%), Positives = 152/362 (41%), Gaps = 42/362 (11%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAA---------- 50
+ +P +KP PR + + + E PSKP EK ++E KAA
Sbjct: 353 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEK--TEESKAAAPAPVSEAVC 408
Query: 51 -----SLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQ---- 101
S+ S+ GT V A + + K + +P + K V + ++K++
Sbjct: 409 RTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEA-DPEDGKPVMDKVKEKAKEEDR 467
Query: 102 ---STKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAG 158
K +++P D K + + +++Q S + +G ++ +
Sbjct: 468 EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASS 527
Query: 159 ITAISGKPGDKKKEKKSLTPAVPVES-KPDKPSGKS--GMDAALDDLIDTLGGPEETEEE 215
+ K E S TPA ++ P + + +S +D ALD L D+LG + +E
Sbjct: 528 LKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDE 587
Query: 216 NTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITGPPA----DSSKPIG 269
N +V + + + ++LG+R+ TIPP+YR LL ++ PP DS KP
Sbjct: 588 NKPME-DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPAD 646
Query: 270 PDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRKVE 324
D IDALS D +C S T + T K++ + + A G + +A E+ K +
Sbjct: 647 DQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPK 706
Query: 325 KD 326
D
Sbjct: 707 DD 708
>gi|109637771 calpastatin isoform l [Homo sapiens]
Length = 654
Score = 1286 bits (3328), Expect = 0.0
Identities = 654/667 (98%), Positives = 654/667 (98%), Gaps = 13/667 (1%)
Query: 84 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 143
MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT
Sbjct: 1 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
Query: 144 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI 203
KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI
Sbjct: 61 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLI 120
Query: 204 DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPAD 263
DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK
Sbjct: 121 DTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK---------- 170
Query: 264 SSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV 323
PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV
Sbjct: 171 ---PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKV 227
Query: 324 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 383
EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL
Sbjct: 228 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 287
Query: 384 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA 443
KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA
Sbjct: 288 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA 347
Query: 444 PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK 503
PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK
Sbjct: 348 PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK 407
Query: 504 AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG 563
AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG
Sbjct: 408 AKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSG 467
Query: 564 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR 623
PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR
Sbjct: 468 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR 527
Query: 624 QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS 683
QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS
Sbjct: 528 QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS 587
Query: 684 KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 743
KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE
Sbjct: 588 KKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 647
Query: 744 TSKPKDD 750
TSKPKDD
Sbjct: 648 TSKPKDD 654
Score = 223 bits (568), Expect = 5e-58
Identities = 188/630 (29%), Positives = 304/630 (48%), Gaps = 49/630 (7%)
Query: 16 RAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASL----GSSQSSRTYAGGTASATKV 71
+ A +R + SEK++E +KP + + + A + G + A V
Sbjct: 40 KKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPV 99
Query: 72 SASSGATSKSSSMNPTETKAVKT--EPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRS 129
+ S S M+ + T PE+ + + P+ + S + ++ R
Sbjct: 100 ESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSS--TYIEELGKRE 157
Query: 130 AEQQPSEKSTEPK-TKPQDMISA-GGESVAGITAISGKPGDKKKEKK--------SLTPA 179
P + K P D I A + G +GK +K++ + ++ A
Sbjct: 158 VTIPPKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSA 217
Query: 180 VPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMS-STYIEELGK 238
P + K K + D AL+ L +L G + E E + EV + + +E+ G+
Sbjct: 218 APPQEKKRKVEKDTMSDQALEALSASL-GTRQAEPELDLRSIKEVDEAKAKEEKLEKCGE 276
Query: 239 REVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDALSSDFTCG----SPTAAGK 291
+ TIP +YR + K+G + P + KP + ID LS DF P+ +
Sbjct: 277 DDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTE 336
Query: 292 KTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQA 345
KTE+ ++ +E + S +++SA P + K T+ D A+EAL+ SLG ++A
Sbjct: 337 KTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDAVEALADSLGKKEA 392
Query: 346 EPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-EPEEKPKP 404
+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E +E+ P
Sbjct: 393 DPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPP 451
Query: 405 RSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQS-APPE 463
SE L+D LSEDF + + + K E++K A A +SE V +T + Q+ APP
Sbjct: 452 MSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTTQAGAPPR 504
Query: 464 PATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDY 523
+ DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++TIPP+Y
Sbjct: 505 DTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEY 564
Query: 524 RLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAI 581
R + KP+ P K+S++ P + +DALS D + + AK
Sbjct: 565 RHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKK 624
Query: 582 SEVVSQTPASTTQAGAPPRDTSQSDKDLDD 611
+ S+ P + +A + T ++ K DD
Sbjct: 625 AASSSKAPKNGGKAKDSAKTTEETSKPKDD 654
Score = 79.7 bits (195), Expect = 9e-15
Identities = 88/362 (24%), Positives = 152/362 (41%), Gaps = 42/362 (11%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAA---------- 50
+ +P +KP PR + + + E PSKP EK ++E KAA
Sbjct: 299 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEK--TEESKAAAPAPVSEAVC 354
Query: 51 -----SLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQ---- 101
S+ S+ GT V A + + K + +P + K V + ++K++
Sbjct: 355 RTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEA-DPEDGKPVMDKVKEKAKEEDR 413
Query: 102 ---STKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAG 158
K +++P D K + + +++Q S + +G ++ +
Sbjct: 414 EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASS 473
Query: 159 ITAISGKPGDKKKEKKSLTPAVPVES-KPDKPSGKS--GMDAALDDLIDTLGGPEETEEE 215
+ K E S TPA ++ P + + +S +D ALD L D+LG + +E
Sbjct: 474 LKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDE 533
Query: 216 NTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITGPPA----DSSKPIG 269
N +V + + + ++LG+R+ TIPP+YR LL ++ PP DS KP
Sbjct: 534 NKPME-DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPAD 592
Query: 270 PDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRKVE 324
D IDALS D +C S T + T K++ + + A G + +A E+ K +
Sbjct: 593 DQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPK 652
Query: 325 KD 326
D
Sbjct: 653 DD 654
>gi|109637769 calpastatin isoform k [Homo sapiens]
Length = 673
Score = 1275 bits (3298), Expect = 0.0
Identities = 654/686 (95%), Positives = 654/686 (95%), Gaps = 32/686 (4%)
Query: 84 MNPTETKAVKTEPEKKSQSTK-------------------PKSLPKQASDTGSNDAHNKK 124
MNPTETKAVKTEPEKKSQSTK PKSLPKQASDTGSNDAHNKK
Sbjct: 1 MNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKK 60
Query: 125 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 184
AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES
Sbjct: 61 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES 120
Query: 185 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 244
KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP
Sbjct: 121 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 180
Query: 245 PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 304
PKYRELLAK PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA
Sbjct: 181 PKYRELLAK-------------PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 227
Query: 305 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 364
QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE
Sbjct: 228 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 287
Query: 365 EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK 424
EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK
Sbjct: 288 EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECK 347
Query: 425 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 484
EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG
Sbjct: 348 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG 407
Query: 485 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 544
KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ
Sbjct: 408 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 467
Query: 545 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 604
LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ
Sbjct: 468 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ 527
Query: 605 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 664
SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL
Sbjct: 528 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 587
Query: 665 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 724
DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS
Sbjct: 588 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 647
Query: 725 SKAPKNGGKAKDSAKTTEETSKPKDD 750
SKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 648 SKAPKNGGKAKDSAKTTEETSKPKDD 673
Score = 223 bits (568), Expect = 5e-58
Identities = 188/630 (29%), Positives = 304/630 (48%), Gaps = 49/630 (7%)
Query: 16 RAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASL----GSSQSSRTYAGGTASATKV 71
+ A +R + SEK++E +KP + + + A + G + A V
Sbjct: 59 KKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPV 118
Query: 72 SASSGATSKSSSMNPTETKAVKT--EPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRS 129
+ S S M+ + T PE+ + + P+ + S + ++ R
Sbjct: 119 ESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSS--TYIEELGKRE 176
Query: 130 AEQQPSEKSTEPK-TKPQDMISA-GGESVAGITAISGKPGDKKKEKK--------SLTPA 179
P + K P D I A + G +GK +K++ + ++ A
Sbjct: 177 VTIPPKYRELLAKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSA 236
Query: 180 VPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMS-STYIEELGK 238
P + K K + D AL+ L +L G + E E + EV + + +E+ G+
Sbjct: 237 APPQEKKRKVEKDTMSDQALEALSASL-GTRQAEPELDLRSIKEVDEAKAKEEKLEKCGE 295
Query: 239 REVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDALSSDFTCG----SPTAAGK 291
+ TIP +YR + K+G + P + KP + ID LS DF P+ +
Sbjct: 296 DDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTE 355
Query: 292 KTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQA 345
KTE+ ++ +E + S +++SA P + K T+ D A+EAL+ SLG ++A
Sbjct: 356 KTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDAVEALADSLGKKEA 411
Query: 346 EPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-EPEEKPKP 404
+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E +E+ P
Sbjct: 412 DPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPP 470
Query: 405 RSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQS-APPE 463
SE L+D LSEDF + + + K E++K A A +SE V +T + Q+ APP
Sbjct: 471 MSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTTQAGAPPR 523
Query: 464 PATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDY 523
+ DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++TIPP+Y
Sbjct: 524 DTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEY 583
Query: 524 RLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAI 581
R + KP+ P K+S++ P + +DALS D + + AK
Sbjct: 584 RHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKK 643
Query: 582 SEVVSQTPASTTQAGAPPRDTSQSDKDLDD 611
+ S+ P + +A + T ++ K DD
Sbjct: 644 AASSSKAPKNGGKAKDSAKTTEETSKPKDD 673
Score = 79.7 bits (195), Expect = 9e-15
Identities = 88/362 (24%), Positives = 152/362 (41%), Gaps = 42/362 (11%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAA---------- 50
+ +P +KP PR + + + E PSKP EK ++E KAA
Sbjct: 318 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEK--TEESKAAAPAPVSEAVC 373
Query: 51 -----SLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQ---- 101
S+ S+ GT V A + + K + +P + K V + ++K++
Sbjct: 374 RTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEA-DPEDGKPVMDKVKEKAKEEDR 432
Query: 102 ---STKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAG 158
K +++P D K + + +++Q S + +G ++ +
Sbjct: 433 EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASS 492
Query: 159 ITAISGKPGDKKKEKKSLTPAVPVES-KPDKPSGKS--GMDAALDDLIDTLGGPEETEEE 215
+ K E S TPA ++ P + + +S +D ALD L D+LG + +E
Sbjct: 493 LKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDE 552
Query: 216 NTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITGPPA----DSSKPIG 269
N +V + + + ++LG+R+ TIPP+YR LL ++ PP DS KP
Sbjct: 553 NKPME-DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPAD 611
Query: 270 PDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRKVE 324
D IDALS D +C S T + T K++ + + A G + +A E+ K +
Sbjct: 612 DQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPK 671
Query: 325 KD 326
D
Sbjct: 672 DD 673
>gi|27765087 calpastatin isoform c [Homo sapiens]
Length = 430
Score = 781 bits (2017), Expect = 0.0
Identities = 391/393 (99%), Positives = 392/393 (99%), Gaps = 1/393 (0%)
Query: 358 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 417
D+AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED
Sbjct: 39 DQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 98
Query: 418 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 477
FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE
Sbjct: 99 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 158
Query: 478 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 537
ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL
Sbjct: 159 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 218
Query: 538 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 597
PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA
Sbjct: 219 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 278
Query: 598 PPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 657
PPRDTS SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP
Sbjct: 279 PPRDTS-SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 337
Query: 658 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 717
PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK
Sbjct: 338 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 397
Query: 718 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 750
CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 398 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
Score = 206 bits (525), Expect = 5e-53
Identities = 144/396 (36%), Positives = 213/396 (53%), Gaps = 30/396 (7%)
Query: 233 IEELGKREVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDALSSDFTCGSPTAA 289
+E+ G+ + TIP +YR + K+G + P + KP + ID LS DF
Sbjct: 48 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSE--CK 105
Query: 290 GKKTEKEESTEVLKAQSAGTVRSA-----------APPQEKKRKVEKDTMSDQALEALSA 338
K ++ E TE KA + V A APP+ K T+ D A+EAL+
Sbjct: 106 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLK---GTVPDDAVEALAD 162
Query: 339 SLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-E 397
SLG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E
Sbjct: 163 SLGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKE 221
Query: 398 PEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSI 457
+E+ P SE L+D LSEDF + + + K E++K A A +SE V +T +
Sbjct: 222 SKEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTT 274
Query: 458 QSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEE 517
Q+ P T DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++
Sbjct: 275 QAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDD 334
Query: 518 TIPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDA 575
TIPP+YR + KP+ P K+S++ P + +DALS D + + A
Sbjct: 335 TIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTA 394
Query: 576 KLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 611
K + S+ P + +A + T ++ K DD
Sbjct: 395 KDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
Score = 81.6 bits (200), Expect = 2e-15
Identities = 88/361 (24%), Positives = 149/361 (41%), Gaps = 41/361 (11%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAA---------- 50
+ +P +KP PR + + + E PSKP EK ++E KAA
Sbjct: 76 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEK--TEESKAAAPAPVSEAVC 131
Query: 51 -----SLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQST-- 103
S+ S+ GT V A + + K + +P + K V + ++K++
Sbjct: 132 RTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEA-DPEDGKPVMDKVKEKAKEEDR 190
Query: 104 -----KPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAG 158
K +++P D K + + +++Q S + +G ++ +
Sbjct: 191 EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASS 250
Query: 159 ITAISGKPGDKKKEKKSLTPAVPVES--KPDKPSGKSGMDAALDDLIDTLGGPEETEEEN 216
+ K E S TPA ++ P S +D ALD L D+LG + +EN
Sbjct: 251 LKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDEN 310
Query: 217 TTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITGPPA----DSSKPIGP 270
+V + + + ++LG+R+ TIPP+YR LL ++ PP DS KP
Sbjct: 311 KPMED-KVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADD 369
Query: 271 DDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRKVEK 325
D IDALS D +C S T + T K++ + + A G + +A E+ K +
Sbjct: 370 QDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKD 429
Query: 326 D 326
D
Sbjct: 430 D 430
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 91.3 bits (225), Expect = 3e-18
Identities = 138/596 (23%), Positives = 225/596 (37%), Gaps = 57/596 (9%)
Query: 178 PAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELG 237
P +P S K + + +T+ E+TEE T EV++ EE G
Sbjct: 427 PKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVT---EEVTEEEEKEAKEEEG 483
Query: 238 KREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEE 297
K E + E +E PPA+ + P+ +A S A K EKEE
Sbjct: 484 KEEEG--GEEEEAEGGEEETKSPPAEEAA--SPEK--EAKSPVKEEAKSPAEAKSPEKEE 537
Query: 298 STEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEV 357
+ + +S +S A + K K ++A + P + K
Sbjct: 538 AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKE--EAKSP 595
Query: 358 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 417
EAK+ E+ E+ ++ P+E + + + PE+ P E E ++
Sbjct: 596 AEAKSPEKAKSPVKEEAKS-PAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654
Query: 418 FDRSECK--EKPSKPTEKTEESKAAAPAPV-SEAVCRTSMCS-IQSAPPEPATLKGTVPD 473
++ E K EK P + +S A +PV +EA S ++ P K V +
Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714
Query: 474 DAVEA-LADSLGKKEAD-PEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDK 531
+A A S K+EA PE K VKE+AK ++ K EK +T+ +VK
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAK---SPVKEEAKSPEKAKSPEKAKTL-------DVKSP 764
Query: 532 DGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAA--------AISE 583
+ K +E++ E + E+ P+ A S EDAK S
Sbjct: 765 EAKTPAKEEARSPADKFPEK-AKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823
Query: 584 VVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKA-- 641
V + + PP+ + ++ DS + P + KP ++ KE A
Sbjct: 824 VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE 883
Query: 642 -----KAEHRDKLGERDDTIP-PEYRHLLDDNGQDKPVKPPTKKSEDSKKPAD--DQDPI 693
K E + + E +P PE ++ P K K+ K+ + ++P
Sbjct: 884 KPKESKVEAKKEEAEDKKKVPTPE---------KEAPAKVEVKEDAKPKEKTEVAKKEPD 934
Query: 694 DALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKT-TEETSKPK 748
DA + + E + K +KA + PK KAK+ KT ++E SKPK
Sbjct: 935 DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPK 990
Score = 89.4 bits (220), Expect = 1e-17
Identities = 130/548 (23%), Positives = 220/548 (40%), Gaps = 48/548 (8%)
Query: 23 THEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSS 82
T E E+ E+ + G+++ E++ A G ++ A AS K + S K
Sbjct: 467 TEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSP---VKEE 523
Query: 83 SMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPK 142
+ +P E K+ + E K K P++A +A + ++S E++ ++ E K
Sbjct: 524 AKSPAEAKSPEKEEAKSPAEVKS---PEKAKSPAKEEAKSPPE-AKSPEKEEAKSPAEVK 579
Query: 143 TKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAV---PVESKPDKPSGKSGMDAAL 199
+ + A E+ + A S + ++++ +PA PV+ + P+ + A
Sbjct: 580 SPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAK 639
Query: 200 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKK----E 255
+ PE+ + PE + S + K E P K + + + E
Sbjct: 640 SPTKEEAKSPEKAKS-------PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPE 692
Query: 256 GITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAP 315
P + +K P+ A + + SP A K KEE+ KA+S V+ A
Sbjct: 693 KAKSPVKEEAK--SPEKAKSPVKEE--AKSPEKA-KSPVKEEAKTPEKAKSP--VKEEAK 745
Query: 316 PQEKKRKVEK----DTMSDQA-LEALSASLGTRQAEPELDLRSIKEVDEA--KAKEEKLE 368
EK + EK D S +A A + PE +KE ++ KAK E
Sbjct: 746 SPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKE 805
Query: 369 KCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESEL-IDELSEDFDRSECKEKP 427
++ IP + +K ++ KP + +E PK E + +E+ S+ +E P
Sbjct: 806 DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAP 865
Query: 428 SK--PTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGK 485
K P K EE K A E S A E A K VP EA A K
Sbjct: 866 KKEAPKPKVEEKKEPAVEKPKE--------SKVEAKKEEAEDKKKVPTPEKEAPAKVEVK 917
Query: 486 KEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIP--PDYRLEEVKDKDGKPLLPKESKE 543
++A P++ V K + AK ++ K EK+E P D + E+ K + KP ++KE
Sbjct: 918 EDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKE 977
Query: 544 QLPPMSED 551
+S++
Sbjct: 978 DDKTLSKE 985
Score = 86.7 bits (213), Expect = 7e-17
Identities = 116/527 (22%), Positives = 197/527 (37%), Gaps = 36/527 (6%)
Query: 33 ESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTETKAV 92
E+ S P E+ S EK+A S ++ + + + + S + +P + +A
Sbjct: 500 ETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA- 558
Query: 93 KTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAG 152
K+ PE KS + P + + K+ AE + EK+ P ++ +
Sbjct: 559 KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPV---KEEAKSP 615
Query: 153 GESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEET 212
E+ + + + P + K +K+ +P P+K +A + + E
Sbjct: 616 AEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAK 675
Query: 213 EEENTTYTGPEVSDPMSSTYIEELGKREVTIPPK----YRELLAKKEGITGPPADSSKPI 268
E P ++ S + K E P K +E E P + +K
Sbjct: 676 SPEKAK--SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKT- 732
Query: 269 GPDDAIDALSSDFTCGSPTAAGKKTEKEESTEV----LKAQSAGTVRSAAP--PQEKKRK 322
P+ A + + SP A K EK ++ +V K + RS A P++ K
Sbjct: 733 -PEKAKSPVKEE--AKSPEKA-KSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP 788
Query: 323 VEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYR 382
V+++ S E + L PE ++ +EV +EEK ++ + +E
Sbjct: 789 VKEEVKSP---EKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845
Query: 383 LKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES--KAA 440
PAT K + + EE PK + ++E E K K SK K EE+ K
Sbjct: 846 KAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE---KPKESKVEAKKEEAEDKKK 902
Query: 441 APAPVSEAVCRTSMCS-------IQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDG 493
P P EA + + + A EP K P E + KK+ E
Sbjct: 903 VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKA 962
Query: 494 KPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKE 540
K +K K +AK ++ +K KE + P + E+ D K P E
Sbjct: 963 KKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPE 1009
Score = 85.1 bits (209), Expect = 2e-16
Identities = 122/528 (23%), Positives = 208/528 (39%), Gaps = 67/528 (12%)
Query: 247 YRELLAKKEGITG-PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQ 305
YR+LL +E G P S P G I ++S+ S + E+ T +++ Q
Sbjct: 402 YRKLLEGEECRIGFGPIPFSLPEGLPK-IPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQ 460
Query: 306 SAGT-VRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQ---------AEPELDLRS-I 354
+ T V +E+K E++ ++ E A G + A PE + +S +
Sbjct: 461 TEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPV 520
Query: 355 KEVDE--AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELID 412
KE + A+AK + E+ E E PA ++ P + EK + +S +E+
Sbjct: 521 KEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEV-- 578
Query: 413 ELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVP 472
S + +S KE+ P E KA +P ++ PA K V
Sbjct: 579 -KSPEKAKSPAKEEAKSPAEAKSPEKAKSP--------------VKEEAKSPAEAKSPVK 623
Query: 473 DDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKD 532
++A K A+ + + KE+AK ++ K EKEE P+ VK +
Sbjct: 624 EEA---------KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674
Query: 533 GKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPAST 592
P K S + S + + E+ P+ A S E+AK V + +
Sbjct: 675 KSPEKAK-SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTP 733
Query: 593 TQAGAPPRDTSQSD---------KDLDDALDKLSDSLGQRQPDPDENKPMEDK--VKEKA 641
+A +P ++ ++S K LD + + P + P + K VKE+
Sbjct: 734 EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEV 793
Query: 642 KAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLD 701
K+ + K ++D PE + + + VK P K+ E ++ + P A + +
Sbjct: 794 KSPEKAKSPLKEDAKAPE-----KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA---EEE 845
Query: 702 SCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKD 749
P+T +T + KD K+ A +AP K K K KPK+
Sbjct: 846 KAPATPKTEEK--KDSKKEEAPKKEAP----KPKVEEKKEPAVEKPKE 887
Score = 81.3 bits (199), Expect = 3e-15
Identities = 146/640 (22%), Positives = 243/640 (37%), Gaps = 83/640 (12%)
Query: 68 ATKVSASSGATSKSSSMNPTETKAVK--TEPEKKSQSTKPKSLPKQASDTGSNDAHNKKA 125
+T + S K + ET V+ TE + ++ + + + G + ++
Sbjct: 433 STHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEE 492
Query: 126 VSRSAEQQ----PSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVP 181
+ E++ P+E++ P+ + + + +S A K +K++ K P
Sbjct: 493 EAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPA-----EAKSPEKEEAKSPAEVKSP 547
Query: 182 VESK-PDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDP--MSSTYIEELGK 238
++K P K KS +A PE+ E ++ EV P S EE
Sbjct: 548 EKAKSPAKEEAKSPPEAK---------SPEKEEAKSPA----EVKSPEKAKSPAKEEAKS 594
Query: 239 REVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDA-LSSDFTCGSPTAA-GKKTEKE 296
P+ + K+E + PA++ P+ + A + S SPT K EK
Sbjct: 595 PAEAKSPEKAKSPVKEEAKS--PAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKA 652
Query: 297 ESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQA--EPELDLRSI 354
+S E +A+S +S + K + K + +A A ++ PE +
Sbjct: 653 KSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPV 712
Query: 355 KEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDEL 414
KE EAK+ E+ E+ +T E P ++ P EK K +++ +D
Sbjct: 713 KE--EAKSPEKAKSPVKEEAKT--PEKAKSPVKEEAKSP------EKAKSPEKAKTLDVK 762
Query: 415 SEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDD 474
S + ++ KE+ P +K E A +PV E V P K + +D
Sbjct: 763 SPEA-KTPAKEEARSPADKFPEK---AKSPVKEEV------------KSPEKAKSPLKED 806
Query: 475 AVEALADSLGKKEADP----EDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKD 530
A +A + KKE E+ KP KVKE K+ + EK P + EE KD
Sbjct: 807 A-KAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA-------PATPKTEEKKD 858
Query: 531 KDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPA 590
K PK KE P E+ A+ + A + ED K E +
Sbjct: 859 SK-KEEAPK--KEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPT-PEKEAPAKV 914
Query: 591 STTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPM--------EDKVKEKAK 642
+ P T + K+ DDA K +++ E K E+K K +AK
Sbjct: 915 EVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAK 974
Query: 643 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSED 682
A+ DK ++ + P + + K KPP K +ED
Sbjct: 975 AKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATED 1014
Score = 71.2 bits (173), Expect = 3e-12
Identities = 100/473 (21%), Positives = 180/473 (38%), Gaps = 44/473 (9%)
Query: 4 PGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAG 63
P ++ A SP ++ K+ E P +++ +A S ++S
Sbjct: 553 PAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEA 612
Query: 64 GTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNK 123
+ + K A S + +P + K+ E K + K KS K+ + +
Sbjct: 613 KSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPE--KAKSPEKEEAKSPEKAKSPV 670
Query: 124 KAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPA---- 179
KA ++S E+ S E K+ + E+ + A S + K +K+ +P
Sbjct: 671 KAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA 730
Query: 180 -VPVESK-PDKPSGKSGMDAALDDLIDTLG--GPEETE--EENTTYTGPEVSDPMSSTYI 233
P ++K P K KS A + TL PE +E + + S
Sbjct: 731 KTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVK 790
Query: 234 EELGKREVTIPPKYRELLA------KKEGITGPPADSSKP--IGPDDAIDALSSDFTCGS 285
EE+ E P + A KKE + P + KP + + + +
Sbjct: 791 EEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT 850
Query: 286 PTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQA 345
P KK K+E +A P EK ++ + + ++A + ++A
Sbjct: 851 PKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEA 910
Query: 346 EPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKP--------LLPE 397
+++++ ++AK KE K E ++ + ++ KPA K+ P +
Sbjct: 911 PAKVEVK-----EDAKPKE-KTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKK 964
Query: 398 PEEKPKPRSESELIDE-LSEDFDR---------SECKEKPSKPTEKTEESKAA 440
PEEKPK ++++ D+ LS++ + S +K SKP EK E KAA
Sbjct: 965 PEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAA 1017
Score = 47.8 bits (112), Expect = 4e-05
Identities = 59/270 (21%), Positives = 103/270 (38%), Gaps = 46/270 (17%)
Query: 492 DGKPVMDKVKE--KAKEEDREKLGEK--------EETIPPDYRLEEVKDKDGKPLLPKES 541
+G P + V K K E++ K+ EK EE EEV +++ K +E
Sbjct: 424 EGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEG 483
Query: 542 KEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD 601
KE+ E E G + S E+A + +A +P ++
Sbjct: 484 KEEEGGEEE--------EAEGGEEETKSPPAEEAA-------------SPEKEAKSPVKE 522
Query: 602 TSQSDKDLDDALDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLGERDDTIPPEY 660
++S + + P+ +E K P E K EKAK+ +++ + PE
Sbjct: 523 EAKSPAEA-------------KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEK 569
Query: 661 RHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKK 720
P K + E++K PA+ + P A S + S E +++ K++ K
Sbjct: 570 EEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE-AKSPVKEEAKS 628
Query: 721 AASSSKAPKNGGKAKDSAKTTEETSKPKDD 750
A K K+ AK+ E+ P+ +
Sbjct: 629 PAEVKSPEKAKSPTKEEAKSPEKAKSPEKE 658
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 68.2 bits (165), Expect = 3e-11
Identities = 157/824 (19%), Positives = 286/824 (34%), Gaps = 113/824 (13%)
Query: 5 GQKPAASPRPRRAAAARRTH--EHVSEKTSESPSKPGEK--------KGSDEKKAASLGS 54
G P+ S +R++ + H + S +S + G++ GS +K GS
Sbjct: 112 GPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGS 171
Query: 55 SQS-SRTYAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQAS 113
S SR+ + G A SS + S + + E + K+ + + P +P +
Sbjct: 172 EHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSG 231
Query: 114 DTGSND-AHNKKAVSRSAEQQPS--------EKSTEPKTKPQDMISAG-GESVAGITAIS 163
+ + + S S Q+P+ ++S EPK + S G S+ +
Sbjct: 232 QHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTEL---- 287
Query: 164 GKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDL-------IDTLGGPEETEEEN 216
KP K K P+ P+++ S +D L ++ + + P +TE
Sbjct: 288 -KPSSKAHLTKLKIPSQPLDASAS--GDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSK 344
Query: 217 TTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDA 276
+ E T G+++ P K K + D K +D+
Sbjct: 345 FPFPTKESQQSNFGT-----GEQKRYNPSKTSNGHQSKSMLK----DDLKLSSSEDSDGE 395
Query: 277 LSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEAL 336
D T T ++E A ++ S+ E + ++ S +
Sbjct: 396 QDCDKTMPRSTPGSNSEPSHHNSE--GADNSRDDSSSHSGSESSSGSDSESESSSSDSEA 453
Query: 337 SASLGTRQAEPELDLRSIKEVDE--AKAKEEKLEKCGEDDETIPSEYRLKPA-------- 386
+ + EPE + ++D K K+ D IPS K
Sbjct: 454 NEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGN 513
Query: 387 --TDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAP 444
TD G P+ P +S+ I + SE + S T + P
Sbjct: 514 SYTDTSG----PKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKK 569
Query: 445 VSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGK---KEADPEDGKPVMDKVK 501
+A ++ P L ++P +A K K+ +P +K K
Sbjct: 570 AEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKK 629
Query: 502 EKAKEEDREKLGE------------KEETIPPDYRLEEVKDKDGKPLLPKESKEQ----- 544
K+ + +K E + E++PP + + + + P+ P +E+
Sbjct: 630 YKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFR 689
Query: 545 ---LPPMSEDFLLDALSEDFSGPQNASSL--KFEDAKLAAAISEVVSQT-PASTTQAGAP 598
PM E LL LSE P + L K + L + +T P + P
Sbjct: 690 QRMFSPMEEKELLSPLSE----PDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVP 745
Query: 599 PRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT--- 655
+ T ++ K A +K+S+ ++ + D+N+ E K K K E ++ G + +
Sbjct: 746 EKHTREAQKQ---ASEKVSNKGKRKHKNEDDNRASESK---KPKTEDKNSAGHKPSSNRE 799
Query: 656 ----IPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQ 711
+ + LL P K P + K+ + + S +++ S
Sbjct: 800 SSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSS 859
Query: 712 NTAKDKCKKAASSS-------KAPKNGGKAKDSAKTTEETSKPK 748
+T+K K + +SS KAP + SA T ++SKP+
Sbjct: 860 STSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTL-DSSKPR 902
Score = 57.8 bits (138), Expect = 4e-08
Identities = 129/652 (19%), Positives = 223/652 (34%), Gaps = 136/652 (20%)
Query: 28 SEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPT 87
++++ +S GE+K + K ++ S++ + S G +M P
Sbjct: 349 TKESQQSNFGTGEQKRYNPSKTSN---GHQSKSMLKDDLKLSSSEDSDGEQDCDKTM-PR 404
Query: 88 ETKAVKTEPEKKSQSTKPKSLPKQASDTGS-----NDAHNKKAVSRSAEQQPSEK-STEP 141
T +EP + S +S +GS +D+ ++ + S S +PS+ S EP
Sbjct: 405 STPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEP 464
Query: 142 KTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSG--KSGMDAAL 199
+ P + K ++PA V+S G K G +
Sbjct: 465 EPPPTNKWQLDNWL-------------NKVNPHKVSPASSVDSNIPSSQGYKKEGREQGT 511
Query: 200 DDLIDTLGGPEET------EEENTTYTGPE--------VSDPMSSTYIEELGKREVTIPP 245
+ GP+ET + T G E + S+T +GK++ P
Sbjct: 512 GNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQ----P 567
Query: 246 KYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQ 305
K E A +E G +S P+ D P++ K K +K +
Sbjct: 568 KKAEKAAAEEPRGGLKIESETPV-----------DLASSMPSSRHKAATKGSRKPNIKKE 616
Query: 306 SAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEE 365
S +S+ P +K+K + + S Q R I E D + +
Sbjct: 617 S----KSSPRPTAEKKKYKSTSKSSQ------------------KSREIIETDTSSSD-- 652
Query: 366 KLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP---------KPRSESELIDELSE 416
++ E++P + + + P+ P E+ P E EL+ LSE
Sbjct: 653 -----SDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSE 707
Query: 417 DFDRSECKEK---------PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATL 467
DR K P KP ++TE K + PE T
Sbjct: 708 PDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGE-----------------KKNVPEKHTR 750
Query: 468 KGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEE 527
+ A E +++ +K + +D + K K K ED+ G K + +
Sbjct: 751 E--AQKQASEKVSNKGKRKHKNEDDNRASESK---KPKTEDKNSAGHKPSSNRESSKQSA 805
Query: 528 VKDKD--GKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVV 585
K+KD P P SK+ P +S+ S +++S K
Sbjct: 806 AKEKDLLPSPAGPVPSKD--PKTEHGSRKRTISQSSSLKSSSNSNKETSGS--------- 854
Query: 586 SQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKV 637
S+ +ST++ TS S K++ + S + P D +KP K+
Sbjct: 855 SKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKL 906
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 67.4 bits (163), Expect = 5e-11
Identities = 110/731 (15%), Positives = 250/731 (34%), Gaps = 31/731 (4%)
Query: 28 SEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPT 87
S+ + S S + S + ++ SS SS + + +++++ S SS ++ S S + +
Sbjct: 561 SDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSS 620
Query: 88 ETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQD 147
++K+ ++ E S + KS +SD+ S+D+ + S S+ S S++ D
Sbjct: 621 DSKSDSSKSESDSSDSDSKS---DSSDSNSSDSSDNSDSSDSSNSSNSSDSSD----SSD 673
Query: 148 MISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLG 207
+ S + ++ S D +S + +S S S +++ D ++
Sbjct: 674 SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSD 733
Query: 208 GPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKP 267
+ + +++ + + SS + + + + + +DS+
Sbjct: 734 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD-----SSDSSDSSNSSDSNDS 788
Query: 268 IGPDDAIDAL-SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKD 326
D+ D+ SSD + S ++ + +S+ + ++ ++ + +
Sbjct: 789 SNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS 848
Query: 327 TMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPA 386
SD S S + + D + + ++ E D + +
Sbjct: 849 DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS--------NS 900
Query: 387 TDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVS 446
+D D + S S D S S ++ ++ S ++ + S
Sbjct: 901 SDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS 960
Query: 447 EAVCRTSMCSIQSAPPEPATLKGTVPD--DAVEALADSLGKKEADPEDGKPVMDKVKEKA 504
++ + S+ ++ D D+ ++ S +D D D
Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020
Query: 505 KEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGP 564
+ + + D + D + S+ S+
Sbjct: 1021 SSNSSDSSNSSDSSDSSD-SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079
Query: 565 QNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQS--DKDLDDALDKLSDSLGQ 622
++ S D+ ++ S+ + +S + + D+S S D D+ D S
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1139
Query: 623 RQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLD-DNGQDKPVKPPTKKSE 681
D ++ D ++ D D + + + D + D + S
Sbjct: 1140 NSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1199
Query: 682 DSKKPADDQDPIDA--LSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK 739
DS +D D D+ S DS S+ + N + D + SS + N + DS+
Sbjct: 1200 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSS--NSSDSSDSSD 1257
Query: 740 TTEETSKPKDD 750
+++ TS D+
Sbjct: 1258 SSDSTSDSNDE 1268
Score = 66.2 bits (160), Expect = 1e-10
Identities = 107/723 (14%), Positives = 232/723 (32%), Gaps = 25/723 (3%)
Query: 28 SEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPT 87
S +S+S SD K +S S SS + + +S + S SS + S S N +
Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS 663
Query: 88 ETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQD 147
+ ++ S S+ + + S+D+ N S S++ S+ S + +
Sbjct: 664 NSSD-SSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSN 722
Query: 148 MISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLG 207
S S + ++ S D S + +S S S + D D+
Sbjct: 723 S-SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781
Query: 208 GPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKP 267
+ + N++ + + SS + + + + + + +DSS
Sbjct: 782 SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS------DSDSSNSSDSSNSSDSSDS 835
Query: 268 IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDT 327
D+ D SSD + GS + + +++ S++ + + ++ +
Sbjct: 836 SNSSDSSD--SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893
Query: 328 MSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPAT 387
SD + + S S + + D + + E+ + + + ++
Sbjct: 894 SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS--------DSS 945
Query: 388 DKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSE 447
D + + S+ D S D S S ++ ++ S ++ + S+
Sbjct: 946 DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD 1005
Query: 448 AVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEE 507
+ + ++ + + D+ ++ S +D D + +
Sbjct: 1006 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1065
Query: 508 DREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNA 567
+ + + D E D S S D + S D S N+
Sbjct: 1066 SSDSSDSSDSSDSSDS--SESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1123
Query: 568 SSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDP 627
S ++ S S + S+ + + S D D+ D S D
Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1183
Query: 628 DENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPA 687
++ D ++ D D + + + D + S +S +
Sbjct: 1184 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD-----SSDSSDSSDSSDSSDSNESSDSS 1238
Query: 688 DDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKP 747
D D D+ + S S + S + + D+ + S NG + ++ ++
Sbjct: 1239 DSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHST 1298
Query: 748 KDD 750
DD
Sbjct: 1299 SDD 1301
Score = 61.6 bits (148), Expect = 3e-09
Identities = 120/741 (16%), Positives = 241/741 (32%), Gaps = 51/741 (6%)
Query: 33 ESPSKPGEKKGSDEKKAASLGSSQS----------SRTYAGGTASATKVSASSGATSKSS 82
+ P+ E G+D+ + S +S S S+ G+ S S +TS ++
Sbjct: 463 DDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTN 522
Query: 83 SMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPK 142
+ + + KS S K KS +SD+ S+D+ N S S++ S+ ++
Sbjct: 523 NSDSNGNGNNGNDDNDKSDSGKGKS---DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSD 579
Query: 143 TKPQDMISA-GGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDD 201
+ D S+ +S + ++ S D S + +SK D S KS D++ D
Sbjct: 580 SDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD--SSKSESDSSDSD 637
Query: 202 LIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPP 261
++ + + + + SS + + + + +
Sbjct: 638 SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD-----SSNSSDSSDS 692
Query: 262 ADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKR 321
+DSS D+ D+ SD + S ++ ++ + S + S+ + S+
Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSN---SSDSSDSSNSSDSSDSSDS 749
Query: 322 KVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEY 381
D+ S S + + D + + +++ + + D + S+
Sbjct: 750 SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD- 808
Query: 382 RLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAA 441
+ D S+S S+ D S+ + + +S ++
Sbjct: 809 ---SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSS 865
Query: 442 PAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVK 501
+ S +S S S E + + +DS ++D D D
Sbjct: 866 DSSDSSDSSNSSDSSDSSDSNESSNSSDS---------SDSSNSSDSDSSDSSNSSDSSD 916
Query: 502 EKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDF 561
+ E + + D +S + D+ S D
Sbjct: 917 SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS 976
Query: 562 SGPQNAS----------SLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 611
S N+S S D+ ++ S+ + +S + + D+S S D D
Sbjct: 977 SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS-SDSSD 1035
Query: 612 ALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLD-DNGQD 670
+ D S D ++ D ++ D D + E D N D
Sbjct: 1036 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSD 1095
Query: 671 KPVKPPTKKSEDSKKPADDQDPIDA--LSGDLDSCPSTTETSQNTAKDKCKKAASSSKAP 728
+ S DS +D D D+ S DS S+ + + + D + SS +
Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155
Query: 729 KNGGKAKDSAKTTEETSKPKD 749
+ + + ++S D
Sbjct: 1156 SSDSSDSSDSSDSSDSSDSSD 1176
Score = 58.5 bits (140), Expect = 2e-08
Identities = 114/727 (15%), Positives = 232/727 (31%), Gaps = 52/727 (7%)
Query: 31 TSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTETK 90
T+ S S G+D+ + G +S + + + S+ +S + S SS N +
Sbjct: 521 TNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS--- 577
Query: 91 AVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMIS 150
S S S +SD+ S+D+ N S S++ S S++ D
Sbjct: 578 ---------SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD--- 625
Query: 151 AGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPE 210
KS + + +SK D S + D D+
Sbjct: 626 ---------------------SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSN 664
Query: 211 ETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGP 270
++ +++ + S SS + + + + + + + +DSS
Sbjct: 665 SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSS 724
Query: 271 DDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTM-S 329
D D+ +S + S ++ + S + S+ + S+ D+ S
Sbjct: 725 DS--DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 782
Query: 330 DQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDK 389
+ ++ ++S + + S D + + + + + S +
Sbjct: 783 SDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSS 842
Query: 390 DGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAV 449
D + RS+S + S+ D S + S ++ E S ++ + S +
Sbjct: 843 DSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS-SDSSDSNESSNSSDSSDSSNSS 901
Query: 450 CRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 509
S S S+ ++ D+ E+ S +D + D +
Sbjct: 902 DSDSSDSSNSSDSSDSSNS----SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957
Query: 510 EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNAS- 568
+ D + D S S D + S D S ++S
Sbjct: 958 NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN 1017
Query: 569 ---SLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQS--DKDLDDALDKLSDSLGQR 623
S D+ ++ S+ + +S + + D+S S D D+ D S
Sbjct: 1018 SSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1077
Query: 624 QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLD-DNGQDKPVKPPTKKSED 682
D E+ D ++ D D + + D N D + S D
Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1137
Query: 683 SKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTE 742
S +D D ++ S DS S+ + + + D + SS+ + + + +
Sbjct: 1138 SSNSSDSSDSSES-SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196
Query: 743 ETSKPKD 749
++S D
Sbjct: 1197 DSSDSSD 1203
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 67.0 bits (162), Expect = 6e-11
Identities = 101/401 (25%), Positives = 155/401 (38%), Gaps = 65/401 (16%)
Query: 288 AAGKKTEKEESTEVLKAQSAGTVRSAAPP-------------QEKKRKVEKDTMSDQALE 334
AA +K E+ E+ E A V++ AP QE++ + ++ SDQA E
Sbjct: 491 AAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE 550
Query: 335 ALSASLGT------RQAEPELDLRSIKEVDEAK---AKEEKLEKCGEDDETIPSEYRLKP 385
S G+ Q E E + + E EAK EEK E+ +E + KP
Sbjct: 551 GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP 610
Query: 386 ATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTE-ESKAAAPAP 444
K P P E+ P +S + ++ +S +EK P K+ E K +P
Sbjct: 611 EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV- 669
Query: 445 VSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALAD--SLGKKEADPEDGKPVMDKVKE 502
S P K VP VE +GK E E+ K +VKE
Sbjct: 670 --------------SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK----EVKE 711
Query: 503 KAKEEDREKLGEKEETIPPDYRLEE-VKD----------KDGKPLLPKESKEQLPPMSED 551
KEE EK EK + +P + E VK+ K K L KE+KE+ P+ ++
Sbjct: 712 APKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQE 771
Query: 552 FLLDAL-----SEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSD 606
+ SE+ + A + ED + + E + T + G+ +
Sbjct: 772 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEV-EGKEEVEQETKEKGS---GREEEK 827
Query: 607 KDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRD 647
+ + LD LS + ++ D E K + K EK +E D
Sbjct: 828 GVVTNGLD-LSPADEKKGGDKSEEKVVVTKTVEKITSEGGD 867
Score = 48.5 bits (114), Expect = 2e-05
Identities = 89/391 (22%), Positives = 138/391 (35%), Gaps = 52/391 (13%)
Query: 275 DALSSDFTCGSPTAAGKKTEKEESTE--VLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQA 332
D L+ AA +K + E T G + + PP K++K +
Sbjct: 386 DLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPK 445
Query: 333 LEAL---------SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 383
L+ + ++E E L +I E KEEK E E +E +E
Sbjct: 446 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEE 505
Query: 384 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEK---------- 433
A K PE +E+ + E E +E E+ + ++ + +EK
Sbjct: 506 VAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGE 565
Query: 434 TEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDG 493
EE + A A EA + ++ E AT + V D VE +K P
Sbjct: 566 QEEGETEAEAEGEEAEAKEEK-KVEEKSEEVATKEELVADAKVEK-----PEKAKSPVPK 619
Query: 494 KPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFL 553
PV +K K + E EK ++ P +EE K K P P E K + P
Sbjct: 620 SPVEEKGKSPVPKSPVE---EKGKSPVPKSPVEE-KGKSPVPKSPVEEKGKSPVSK---- 671
Query: 554 LDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDAL 613
+ E P S + E+AK A + + Q + P++ K+
Sbjct: 672 -SPVEEKAKSPVPKSPV--EEAKSKAEVGK-GEQKEEEEKEVKEAPKEEKVEKKE----- 722
Query: 614 DKLSDSLGQRQPDPDENKPMEDKVKEKAKAE 644
++ D E K E VKE+A AE
Sbjct: 723 --------EKPKDVPEKKKAESPVKEEAVAE 745
Score = 39.3 bits (90), Expect = 0.014
Identities = 37/171 (21%), Positives = 65/171 (38%), Gaps = 11/171 (6%)
Query: 29 EKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTE 88
E +E+ ++ E + +EKK +++ A K + KS +
Sbjct: 568 EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGK 627
Query: 89 TKAVKTEPEKKSQSTKPKS---------LPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 139
+ K+ E+K +S PKS +PK + +K V A + P KS
Sbjct: 628 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA-KSPVPKSP 686
Query: 140 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPA-VPVESKPDKP 189
+ K + + G + + P ++K EKK P VP + K + P
Sbjct: 687 VEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESP 737
Score = 38.5 bits (88), Expect = 0.023
Identities = 75/372 (20%), Positives = 130/372 (34%), Gaps = 45/372 (12%)
Query: 4 PGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAG 63
P K + E K+ ++ EK+GS EK+ G + T A
Sbjct: 518 PEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEE---GEQEEGETEAE 574
Query: 64 GTASATKVSASSGATSKSSSMNPTE--TKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAH 121
+ KS + E K E +K++S PKS ++
Sbjct: 575 AEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEE---------K 625
Query: 122 NKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVP 181
K V +S ++ KS PK+ ++ G + + P ++K KS P
Sbjct: 626 GKSPVPKSPVEEKG-KSPVPKSPVEE---------KGKSPVPKSPVEEK--GKSPVSKSP 673
Query: 182 VESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREV 241
VE K P KS ++ A +G E+ EEE EV + +E+ ++
Sbjct: 674 VEEKAKSPVPKSPVEEAKSKA--EVGKGEQKEEEE-----KEVKEAPKEEKVEKKEEKPK 726
Query: 242 TIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEV 301
+P K + KE +K + + G P K EKE++
Sbjct: 727 DVPEKKKAESPVKEEAVAEVVTITKSV----KVHLEKETKEEGKPLQQEK--EKEKAGGE 780
Query: 302 LKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPE------LDLRSIK 355
++ G+ + A +++ V + + +E + G+ + E + LDL
Sbjct: 781 GGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPAD 840
Query: 356 EVDEAKAKEEKL 367
E EEK+
Sbjct: 841 EKKGGDKSEEKV 852
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 67.0 bits (162), Expect = 6e-11
Identities = 101/401 (25%), Positives = 155/401 (38%), Gaps = 65/401 (16%)
Query: 288 AAGKKTEKEESTEVLKAQSAGTVRSAAPP-------------QEKKRKVEKDTMSDQALE 334
AA +K E+ E+ E A V++ AP QE++ + ++ SDQA E
Sbjct: 115 AAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE 174
Query: 335 ALSASLGT------RQAEPELDLRSIKEVDEAK---AKEEKLEKCGEDDETIPSEYRLKP 385
S G+ Q E E + + E EAK EEK E+ +E + KP
Sbjct: 175 GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP 234
Query: 386 ATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTE-ESKAAAPAP 444
K P P E+ P +S + ++ +S +EK P K+ E K +P
Sbjct: 235 EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV- 293
Query: 445 VSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALAD--SLGKKEADPEDGKPVMDKVKE 502
S P K VP VE +GK E E+ K +VKE
Sbjct: 294 --------------SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK----EVKE 335
Query: 503 KAKEEDREKLGEKEETIPPDYRLEE-VKD----------KDGKPLLPKESKEQLPPMSED 551
KEE EK EK + +P + E VK+ K K L KE+KE+ P+ ++
Sbjct: 336 APKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQE 395
Query: 552 FLLDAL-----SEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSD 606
+ SE+ + A + ED + + E + T + G+ +
Sbjct: 396 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEV-EGKEEVEQETKEKGS---GREEEK 451
Query: 607 KDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRD 647
+ + LD LS + ++ D E K + K EK +E D
Sbjct: 452 GVVTNGLD-LSPADEKKGGDKSEEKVVVTKTVEKITSEGGD 491
Score = 48.5 bits (114), Expect = 2e-05
Identities = 89/391 (22%), Positives = 138/391 (35%), Gaps = 52/391 (13%)
Query: 275 DALSSDFTCGSPTAAGKKTEKEESTE--VLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQA 332
D L+ AA +K + E T G + + PP K++K +
Sbjct: 10 DLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPK 69
Query: 333 LEAL---------SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 383
L+ + ++E E L +I E KEEK E E +E +E
Sbjct: 70 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEE 129
Query: 384 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEK---------- 433
A K PE +E+ + E E +E E+ + ++ + +EK
Sbjct: 130 VAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGE 189
Query: 434 TEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDG 493
EE + A A EA + ++ E AT + V D VE +K P
Sbjct: 190 QEEGETEAEAEGEEAEAKEEK-KVEEKSEEVATKEELVADAKVEK-----PEKAKSPVPK 243
Query: 494 KPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFL 553
PV +K K + E EK ++ P +EE K K P P E K + P
Sbjct: 244 SPVEEKGKSPVPKSPVE---EKGKSPVPKSPVEE-KGKSPVPKSPVEEKGKSPVSK---- 295
Query: 554 LDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDAL 613
+ E P S + E+AK A + + Q + P++ K+
Sbjct: 296 -SPVEEKAKSPVPKSPV--EEAKSKAEVGK-GEQKEEEEKEVKEAPKEEKVEKKE----- 346
Query: 614 DKLSDSLGQRQPDPDENKPMEDKVKEKAKAE 644
++ D E K E VKE+A AE
Sbjct: 347 --------EKPKDVPEKKKAESPVKEEAVAE 369
Score = 39.3 bits (90), Expect = 0.014
Identities = 37/171 (21%), Positives = 65/171 (38%), Gaps = 11/171 (6%)
Query: 29 EKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTE 88
E +E+ ++ E + +EKK +++ A K + KS +
Sbjct: 192 EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGK 251
Query: 89 TKAVKTEPEKKSQSTKPKS---------LPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 139
+ K+ E+K +S PKS +PK + +K V A + P KS
Sbjct: 252 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA-KSPVPKSP 310
Query: 140 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPA-VPVESKPDKP 189
+ K + + G + + P ++K EKK P VP + K + P
Sbjct: 311 VEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESP 361
Score = 38.5 bits (88), Expect = 0.023
Identities = 75/372 (20%), Positives = 130/372 (34%), Gaps = 45/372 (12%)
Query: 4 PGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAG 63
P K + E K+ ++ EK+GS EK+ G + T A
Sbjct: 142 PEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEE---GEQEEGETEAE 198
Query: 64 GTASATKVSASSGATSKSSSMNPTE--TKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAH 121
+ KS + E K E +K++S PKS ++
Sbjct: 199 AEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEE---------K 249
Query: 122 NKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVP 181
K V +S ++ KS PK+ ++ G + + P ++K KS P
Sbjct: 250 GKSPVPKSPVEEKG-KSPVPKSPVEE---------KGKSPVPKSPVEEK--GKSPVSKSP 297
Query: 182 VESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREV 241
VE K P KS ++ A +G E+ EEE EV + +E+ ++
Sbjct: 298 VEEKAKSPVPKSPVEEAKSKA--EVGKGEQKEEEE-----KEVKEAPKEEKVEKKEEKPK 350
Query: 242 TIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEV 301
+P K + KE +K + + G P K EKE++
Sbjct: 351 DVPEKKKAESPVKEEAVAEVVTITKSV----KVHLEKETKEEGKPLQQEK--EKEKAGGE 404
Query: 302 LKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPE------LDLRSIK 355
++ G+ + A +++ V + + +E + G+ + E + LDL
Sbjct: 405 GGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPAD 464
Query: 356 EVDEAKAKEEKL 367
E EEK+
Sbjct: 465 EKKGGDKSEEKV 476
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 65.9 bits (159), Expect = 1e-10
Identities = 129/592 (21%), Positives = 215/592 (36%), Gaps = 76/592 (12%)
Query: 7 KPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTA 66
K +P R + TH K E + +K EKKA + + T
Sbjct: 147 KTEKQEKPERKIQTKVTH-----KEKEKGKEKVREKEKPEKKATH--KEKIEKKEKPETK 199
Query: 67 SATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAV 126
+ K + KS E K K E K++ + K K + K S + K AV
Sbjct: 200 TLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQT-AAKVKEVQKTPSKPKEKEDKEKAAV 258
Query: 127 SRSAEQ------------------QPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGD 168
S+ ++ +P + P P + S A+ K G+
Sbjct: 259 SKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQAS---RPTPASPALEEKEGE 315
Query: 169 KKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPM 228
KKK +K +T + K D KS + A+D G ET++ +
Sbjct: 316 KKKAEKKVTSETKKKEKEDIKK-KSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKD 374
Query: 229 SSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTA 288
+ K+ + + KKE P K ++ SD + T
Sbjct: 375 EKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKE-------HSVPSDKQVKAKTE 427
Query: 289 AGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPE 348
K E+ + + KA E++ + EK + L+ G + P
Sbjct: 428 RAK--EEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVP- 484
Query: 349 LDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSES 408
S+KE + K+EK+ K G++ + P + + K K+ KP P+ +++ KP + S
Sbjct: 485 ---ASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGK----KEEKP-EPQIKKEAKP-AIS 535
Query: 409 ELIDELSEDFDRSECKEKPSKPTEKTEE-------SKAAAPAPVSEAVCR-TSMCSIQSA 460
E + +D + E KP EK + K A P P +A R SI++
Sbjct: 536 EKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTD 595
Query: 461 PPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIP 520
P+P T KGT + E+ GKK+ + + + K K K EK+ ++E++
Sbjct: 596 KPKP-TPKGT--SEVTES-----GKKKTEISEKE---SKEKADMKHLREEKVSTRKESL- 643
Query: 521 PDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKF 572
+L V K KP + E +P + +ED S + S + F
Sbjct: 644 ---QLHNV-TKAEKPARVSKDVEDVPASKK---AKEGTEDVSPTKQKSPISF 688
Score = 62.4 bits (150), Expect = 1e-09
Identities = 90/416 (21%), Positives = 156/416 (37%), Gaps = 53/416 (12%)
Query: 3 QPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYA 62
+PGQ PA P A+R T + + E K EKK + E K +
Sbjct: 283 KPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKE 342
Query: 63 GGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQ--ASDTGSNDA 120
K + T + + + A K E ++ S+ TK + +Q +
Sbjct: 343 TAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEK 402
Query: 121 HNKKAVSRSAEQQ-PSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPA 179
H + A S E PS+K + KT+ E + ++ PG KKE+K+ T
Sbjct: 403 HVEPAKSPKKEHSVPSDKQVKAKTE------RAKEEIGAVSIKKAVPG--KKEEKT-TKT 453
Query: 180 VPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKR 239
V E + +K SGK+ + L D + + G EE + PE E++ K
Sbjct: 454 VEQEIRKEK-SGKT--SSILKDK-EPIKGKEEKVPASLKEKEPETKKD------EKMSKA 503
Query: 240 EVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEEST 299
+ PK +L KKE P + + D T + K E+
Sbjct: 504 GKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEE---- 559
Query: 300 EVLKAQSAGTVRSAAPPQEKKR-----------KVEKDTMSDQALEALSAS------LGT 342
+VLK A T+ A P+ K+ K +K + + ++ S +
Sbjct: 560 KVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISE 619
Query: 343 RQAEPELDLRSIKEVDEAKAKE----------EKLEKCGEDDETIPSEYRLKPATD 388
++++ + D++ ++E + KE EK + +D E +P+ + K T+
Sbjct: 620 KESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEGTE 675
Score = 61.6 bits (148), Expect = 3e-09
Identities = 122/627 (19%), Positives = 229/627 (36%), Gaps = 105/627 (16%)
Query: 93 KTEPEKKSQSTKPKSLPKQASDTGSNDAHNK-KAVSRSAEQQPSEKSTEPKTKP---QDM 148
KTE ++K + + + + G K K ++ ++ EK +P+TK +
Sbjct: 147 KTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQK 206
Query: 149 ISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGG 208
+ E T K G ++K K++ V+ P KP
Sbjct: 207 KAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPK------------------ 248
Query: 209 PEETEEENTTYTGPEVSDPMS-STYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKP 267
E+ ++E + E D + Y+ ++ + +L + PP + +
Sbjct: 249 -EKEDKEKAAVSKHEQKDQYAFCRYMIDIFV--------HGDLKPGQSPAIPPPLPTEQA 299
Query: 268 IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDT 327
P A AL KK EK+ ++E K + ++ K+K EK+T
Sbjct: 300 SRPTPASPALEEK------EGEKKKAEKKVTSETKKKEK----------EDIKKKSEKET 343
Query: 328 MSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPAT 387
D + + T+Q ++ ++ + DE K +K +K P+E
Sbjct: 344 AIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKK--------PAEVEQPKGK 395
Query: 388 DKDGKPLLPEPEEKPKPRSESELIDELSEDFDRS-ECKEKPSKPTEKTEESKAAAPAPVS 446
++ K EP + PK E S D+ + K + +K K A P
Sbjct: 396 KQEKKEKHVEPAKSPK--------KEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKE 447
Query: 447 EAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKE 506
E +T I+ K ++ GK+E P K +K E K+
Sbjct: 448 EKTTKTVEQEIRKE-------KSGKTSSILKDKEPIKGKEEKVPASLK---EKEPETKKD 497
Query: 507 EDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQN 566
E K G++ + PP +L+ K++ +P + KE+K P +SE + +D P+
Sbjct: 498 EKMSKAGKEVKPKPP--QLQGKKEEKPEPQIKKEAK---PAISEKVQIH--KQDIVKPEK 550
Query: 567 ASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPD 626
S + K V+ Q A T + A P+ T +++ ++ S+ +P
Sbjct: 551 TVSHGKPEEK-------VLKQVKAVTIEKTAKPKPTKKAEH-----REREPPSIKTDKPK 598
Query: 627 PDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKP 686
P E K K E + E++ + +HL ++ + ++KP
Sbjct: 599 PTPKGTSEVTESGKKKTE----ISEKESKEKADMKHLREEKVSTRKESLQLHNVTKAEKP 654
Query: 687 ADDQDPIDALSGDLDSCPSTTETSQNT 713
A +S D++ P++ + + T
Sbjct: 655 A-------RVSKDVEDVPASKKAKEGT 674
Score = 38.5 bits (88), Expect = 0.023
Identities = 73/352 (20%), Positives = 131/352 (37%), Gaps = 42/352 (11%)
Query: 406 SESELIDELSEDFDRSECKEKPSKPTE----KTEESKAAAPAPVSEAVCRTSMCSIQSAP 461
SE E D+ ED D+ E E P + E KTE+ + ++ + +
Sbjct: 116 SEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVR 175
Query: 462 PEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 521
+ K + +E K A + +K +EK K+E K G++E+
Sbjct: 176 EKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKE--VKGGKQEKVKQT 233
Query: 522 DYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAI 581
+++EV+ KP KE KE+ A+S+ Q A D + +
Sbjct: 234 AAKVKEVQKTPSKP-KEKEDKEKA----------AVSKHEQKDQYAFCRYMIDIFVHGDL 282
Query: 582 SEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKA 641
Q+PA PP T Q+ + S +L +++ E K E KV +
Sbjct: 283 KP--GQSPAI-----PPPLPTEQASRP-----TPASPALEEKE---GEKKKAEKKVTSET 327
Query: 642 KAEHRD---KLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSG 698
K + ++ K E++ I E + + G+ K T K D+ D+
Sbjct: 328 KKKEKEDIKKKSEKETAIDVEKK----EPGKASETKQGTVKIAAQAAAKKDEKKEDSKK- 382
Query: 699 DLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 750
P+ E + ++K +K +K+PK + +T + K++
Sbjct: 383 --TKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEE 432
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 65.5 bits (158), Expect = 2e-10
Identities = 147/738 (19%), Positives = 241/738 (32%), Gaps = 83/738 (11%)
Query: 31 TSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNP---T 87
T++ S G++K + K+ S+ +T A A +KV A +++++ P T
Sbjct: 158 TNKQTSTDGKEKTTSAKETQSI-----EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 212
Query: 88 ETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQD 147
+ T P++ + +T + P + ++SA P E + P T +
Sbjct: 213 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA--PTTTKEP 270
Query: 148 MISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLG 207
+ E T +P + TP P + P KP+ + +
Sbjct: 271 APTTPKEPAPTTTK---EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE----------- 316
Query: 208 GPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKP 267
P T + T T P+ P + K PK KE PA P
Sbjct: 317 -PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-----PA----P 366
Query: 268 IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKD- 326
P + + + + +P T K T + T + P+E K+
Sbjct: 367 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 426
Query: 327 ---TMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 383
T + A T EP + KE K+ E T P E
Sbjct: 427 APTTPKEPAPTTPKKPAPTTPKEPAPT--TPKEPAPTTTKKPAPTTPKEPAPTTPKE--T 482
Query: 384 KPATDKDGKPLLPEP-----EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES- 437
P T K P PE EKP P + EL E+ P+ P E +
Sbjct: 483 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE-------PTPTTPEEPAPTTP 535
Query: 438 KAAAPAPVSEAVCRTSMCSIQSAPPEPA--TLKGTVPDDAVEALADSLGKKEADPEDGKP 495
KAAAP E T + P EPA T K T P + A + K+ A KP
Sbjct: 536 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKKP 594
Query: 496 VMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES-----KEQLPPMSE 550
++ +E +K P K P PKE KE P +
Sbjct: 595 APKELAPTTTKEPTSTTCDKPAPTTP---------KGTAPTTPKEPAPTTPKEPAPTTPK 645
Query: 551 DFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLD 610
L E P + K +LA ++ + T + P + K+
Sbjct: 646 GTAPTTLKE----PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 701
Query: 611 DALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQD 670
K P P ++ ++ H+ D++ P ++
Sbjct: 702 PTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP----DESTPELSAEPTPKALEN 757
Query: 671 KPVKP--PTKKSEDSKKPADDQDPIDALSG-DLDSCPSTTETSQNTAKDKCKKAASSSKA 727
P +P PT K+ + KP D + DL + P TT + K+ ++++
Sbjct: 758 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 817
Query: 728 PKNGGKAKDSAKTTEETS 745
+ ++ TT++T+
Sbjct: 818 KITATTTQVTSTTTQDTT 835
Score = 50.4 bits (119), Expect = 6e-06
Identities = 101/497 (20%), Positives = 164/497 (32%), Gaps = 36/497 (7%)
Query: 266 KPIGPDDAIDALSS-DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVE 324
KP D+A L + DF +P + + K ++ + R + PP K
Sbjct: 81 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 140
Query: 325 KDTMSDQA-LEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 383
T++ + +E + +Q + KE + + + +EK D S+
Sbjct: 141 SLTVNKETTVETKETTTTNKQTSTDG-----KEKTTSAKETQSIEKTSAKDLAPTSKVLA 195
Query: 384 KPATDKDGK---PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAA 440
KP + P L P+E P P + E ++ + K P+ P E + +
Sbjct: 196 KPTPKAETTTKGPALTTPKE-PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 254
Query: 441 APAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKV 500
AP E T+ + P EPA P A + K+ A KP
Sbjct: 255 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 314
Query: 501 KEKAKEEDREKL-GEKEETIPPDYRLEEVKDKDGKPLLPKE-----SKEQLPPMSEDFLL 554
KE A +E +E P K+ P PK+ KE P ++
Sbjct: 315 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 374
Query: 555 DALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAP--PRDTS-QSDKDLDD 611
E + + E A + ++ PA TT AP P++ S + K+
Sbjct: 375 TTTKEP------SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428
Query: 612 ALDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQD 670
K ++P P K P KE A + + T P E
Sbjct: 429 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK----KPAPTTPKEPAPTTPKETAP 484
Query: 671 KPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKN 730
K T + + P + P +L P+T E T ++ + AP
Sbjct: 485 TTPKKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNT 542
Query: 731 GGKAKDSAKTTEETSKP 747
K+ A TT + P
Sbjct: 543 ---PKEPAPTTPKEPAP 556
Score = 47.8 bits (112), Expect = 4e-05
Identities = 100/476 (21%), Positives = 154/476 (32%), Gaps = 63/476 (13%)
Query: 4 PGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAG 63
P K A P+ A + +P+ P E + K+ + + + T
Sbjct: 335 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 394
Query: 64 GTASATKVSA-----SSGATSKSSSMNPTETKAVKTEPE------KKSQSTKPK----SL 108
+ TK A S+ T K S T+ A T E KK T PK +
Sbjct: 395 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 454
Query: 109 PKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGD 168
PK+ + T + K A + E P+ T P+ + E +A T P
Sbjct: 455 PKEPAPTTT----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP-T 509
Query: 169 KKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPM 228
+E TP P + P++P+ + AA +T P T + T P+ P
Sbjct: 510 TPEELAPTTPEEPTPTTPEEPAPTTPKAAA----PNTPKEPAPTTPKEPAPTTPKEPAPT 565
Query: 229 SSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTA 288
+ + T P K+ T P + K + P + S+ TC P
Sbjct: 566 TPK------ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTST--TCDKPAP 617
Query: 289 AGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPE 348
T K + K + T + AP T A L T +P
Sbjct: 618 T---TPKGTAPTTPKEPAPTTPKEPAP----------TTPKGTAPTTLKEPAPTTPKKP- 663
Query: 349 LDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSES 408
+ KE+ K + T P E P T K+ P P+ P +
Sbjct: 664 ----APKELAPTTTKGPTSTTSDKPAPTTPKE--TAPTTPKEPAPTTPKKPAPTTPETPP 717
Query: 409 ELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEP 464
E+S E P E T E +A P P +++++P EP
Sbjct: 718 PTTSEVSTPTTTKEPTTIHKSPDESTPE-LSAEPTPK----------ALENSPKEP 762
Score = 44.3 bits (103), Expect = 4e-04
Identities = 57/267 (21%), Positives = 93/267 (34%), Gaps = 15/267 (5%)
Query: 258 TGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQ 317
T P ++KPI P ++ S S T + T + + T Q++ +
Sbjct: 114 TSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA 173
Query: 318 EKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETI 377
++ + +EK + D A + + T +AE ++ E K E
Sbjct: 174 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 233
Query: 378 PSEYRLKPATDKDGKPL------------LPEPEEKPKPRSESELIDELSEDFDRSECKE 425
P+ + P T K+ P P ++P P + E +++ + K
Sbjct: 234 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 293
Query: 426 KPSKPTEKTEES-KAAAPAPVSEAVCRTSMCSIQSAPPEPA-TLKGTVPDDAVEALADSL 483
P+ P E + K AP E T + P EPA T K P E A +
Sbjct: 294 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-APTA 352
Query: 484 GKKEADPEDGKPVMDKVKEKAKEEDRE 510
KK A +P KE A +E
Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKE 379
Score = 43.5 bits (101), Expect = 7e-04
Identities = 109/515 (21%), Positives = 173/515 (33%), Gaps = 87/515 (16%)
Query: 86 PTETKAVKTEPEKKSQSTKPK----SLPKQASDTGSNDAH--NKKAVSRSAEQQPSEKST 139
PT KA K+ T PK + PK+ + T + K + + ++P+ +T
Sbjct: 532 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP-TT 590
Query: 140 EPKTKPQDMISAGGESVAGITAISGKP----GDKKKEKKSLTPAVPVESKPDKPSGKSGM 195
K P+++ + T P G K P P E P P G +
Sbjct: 591 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-TAP 649
Query: 196 DAALDDLIDTLGGPEETEEENTTYTGPE--VSDPMSSTYIEELGKREVTIPPKYRELLAK 253
+ T P E TT GP SD + T +E T P + K
Sbjct: 650 TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP---TTPKEPAPTTPK 706
Query: 254 KEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSA 313
K T P P +S+ T PT K + EST L A+
Sbjct: 707 KPAPTTPET-------PPPTTSEVSTPTTTKEPTTIHKSPD--ESTPELSAEPTPKALEN 757
Query: 314 AP-----PQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLE 368
+P P K K M+ A + + E DLR+ E A K K E
Sbjct: 758 SPKEPGVPTTKTPAATKPEMTTTAKDKTT----------ERDLRTTPETTTAAPKMTK-E 806
Query: 369 KCGEDDETIPSEY-----RLKPATDKDGKP----------LLPEPEEKPKPRSESELIDE 413
++T S+ ++ T +D P L P+ K + +E++++
Sbjct: 807 TATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNK 866
Query: 414 LSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ-----------SAPP 462
E+ +KP ++ SKA P P S + P
Sbjct: 867 ----------PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTP 916
Query: 463 EPATLKGTVPD-DAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET--- 518
P + T+P+ + +A+++ + P P V+ K ED G + ET
Sbjct: 917 TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ-TPNSKLVEVNPKSEDAG--GAEGETPHM 973
Query: 519 --IPPDYRLEEVKDKDGKPLLPKESKEQLPPMSED 551
P + E D D P +P + P +S++
Sbjct: 974 LLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDE 1008
Score = 39.3 bits (90), Expect = 0.014
Identities = 73/345 (21%), Positives = 112/345 (32%), Gaps = 47/345 (13%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
+ +P P P+ A + +P+ P + K+ A + + T
Sbjct: 583 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 642
Query: 61 YAGGTASATKVSASSGATSKSS--SMNPTETKAVKTEPEKKSQSTKPK----SLPKQASD 114
GTA T + K + + PT TK + K T PK + PK+ +
Sbjct: 643 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 702
Query: 115 TGSNDAHNKKAVSRSAEQQP---SEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKK 171
T KK + E P SE ST TK I + +S +P K
Sbjct: 703 TTP-----KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE--STPELSAEPTPKAL 755
Query: 172 EKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSST 231
E P VP P AA + T + TE + T P ++T
Sbjct: 756 ENSPKEPGVPTTKTP----------AATKPEMTTTAKDKTTERDLRT-------TPETTT 798
Query: 232 YIEELGKREVTIPPKYRE--LLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAA 289
++ K T K E + A +T + P I L + T
Sbjct: 799 AAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF----KITTLKTT-TLAPKVTT 853
Query: 290 GKKT-------EKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDT 327
KKT K E T K ++ + + PQ+ + +K T
Sbjct: 854 TKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPT 898
Score = 32.0 bits (71), Expect = 2.2
Identities = 54/255 (21%), Positives = 93/255 (36%), Gaps = 21/255 (8%)
Query: 502 EKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDF 561
E+ +E D + +K + PDY + KD K K+ PP+ + E
Sbjct: 38 ERGRECDCDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPKPPV--------VDEAG 89
Query: 562 SGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDT--SQSDKDLDDALDKLSDS 619
SG N K + VS +P TT PR + SD + +L ++
Sbjct: 90 SGLDN-GDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 148
Query: 620 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT--IPPEYRHLLDDNGQ-DKPVKPP 676
+ + NK KEK + + E+ + P + L + + K P
Sbjct: 149 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP 208
Query: 677 TKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKC----KKAASSSKAPKNGG 732
+ P ++P A + + P+T +++ T K+ K A ++ K P
Sbjct: 209 ALTTPKEPTPTTPKEP--ASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA-PT 265
Query: 733 KAKDSAKTTEETSKP 747
K+ A TT + P
Sbjct: 266 TTKEPAPTTPKEPAP 280
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 65.5 bits (158), Expect = 2e-10
Identities = 147/738 (19%), Positives = 241/738 (32%), Gaps = 83/738 (11%)
Query: 31 TSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNP---T 87
T++ S G++K + K+ S+ +T A A +KV A +++++ P T
Sbjct: 199 TNKQTSTDGKEKTTSAKETQSI-----EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 253
Query: 88 ETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQD 147
+ T P++ + +T + P + ++SA P E + P T +
Sbjct: 254 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA--PTTTKEP 311
Query: 148 MISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLG 207
+ E T +P + TP P + P KP+ + +
Sbjct: 312 APTTPKEPAPTTTK---EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE----------- 357
Query: 208 GPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKP 267
P T + T T P+ P + K PK KE PA P
Sbjct: 358 -PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-----PA----P 407
Query: 268 IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKD- 326
P + + + + +P T K T + T + P+E K+
Sbjct: 408 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 467
Query: 327 ---TMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 383
T + A T EP + KE K+ E T P E
Sbjct: 468 APTTPKEPAPTTPKKPAPTTPKEPAPT--TPKEPAPTTTKKPAPTTPKEPAPTTPKE--T 523
Query: 384 KPATDKDGKPLLPEP-----EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES- 437
P T K P PE EKP P + EL E+ P+ P E +
Sbjct: 524 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE-------PTPTTPEEPAPTTP 576
Query: 438 KAAAPAPVSEAVCRTSMCSIQSAPPEPA--TLKGTVPDDAVEALADSLGKKEADPEDGKP 495
KAAAP E T + P EPA T K T P + A + K+ A KP
Sbjct: 577 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKKP 635
Query: 496 VMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES-----KEQLPPMSE 550
++ +E +K P K P PKE KE P +
Sbjct: 636 APKELAPTTTKEPTSTTCDKPAPTTP---------KGTAPTTPKEPAPTTPKEPAPTTPK 686
Query: 551 DFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLD 610
L E P + K +LA ++ + T + P + K+
Sbjct: 687 GTAPTTLKE----PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 742
Query: 611 DALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQD 670
K P P ++ ++ H+ D++ P ++
Sbjct: 743 PTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP----DESTPELSAEPTPKALEN 798
Query: 671 KPVKP--PTKKSEDSKKPADDQDPIDALSG-DLDSCPSTTETSQNTAKDKCKKAASSSKA 727
P +P PT K+ + KP D + DL + P TT + K+ ++++
Sbjct: 799 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 858
Query: 728 PKNGGKAKDSAKTTEETS 745
+ ++ TT++T+
Sbjct: 859 KITATTTQVTSTTTQDTT 876
Score = 50.4 bits (119), Expect = 6e-06
Identities = 101/497 (20%), Positives = 164/497 (32%), Gaps = 36/497 (7%)
Query: 266 KPIGPDDAIDALSS-DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVE 324
KP D+A L + DF +P + + K ++ + R + PP K
Sbjct: 122 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 181
Query: 325 KDTMSDQA-LEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 383
T++ + +E + +Q + KE + + + +EK D S+
Sbjct: 182 SLTVNKETTVETKETTTTNKQTSTDG-----KEKTTSAKETQSIEKTSAKDLAPTSKVLA 236
Query: 384 KPATDKDGK---PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAA 440
KP + P L P+E P P + E ++ + K P+ P E + +
Sbjct: 237 KPTPKAETTTKGPALTTPKE-PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 295
Query: 441 APAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKV 500
AP E T+ + P EPA P A + K+ A KP
Sbjct: 296 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 355
Query: 501 KEKAKEEDREKL-GEKEETIPPDYRLEEVKDKDGKPLLPKE-----SKEQLPPMSEDFLL 554
KE A +E +E P K+ P PK+ KE P ++
Sbjct: 356 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 415
Query: 555 DALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAP--PRDTS-QSDKDLDD 611
E + + E A + ++ PA TT AP P++ S + K+
Sbjct: 416 TTTKEP------SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469
Query: 612 ALDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQD 670
K ++P P K P KE A + + T P E
Sbjct: 470 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK----KPAPTTPKEPAPTTPKETAP 525
Query: 671 KPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKN 730
K T + + P + P +L P+T E T ++ + AP
Sbjct: 526 TTPKKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNT 583
Query: 731 GGKAKDSAKTTEETSKP 747
K+ A TT + P
Sbjct: 584 ---PKEPAPTTPKEPAP 597
Score = 47.8 bits (112), Expect = 4e-05
Identities = 100/476 (21%), Positives = 154/476 (32%), Gaps = 63/476 (13%)
Query: 4 PGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAG 63
P K A P+ A + +P+ P E + K+ + + + T
Sbjct: 376 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 435
Query: 64 GTASATKVSA-----SSGATSKSSSMNPTETKAVKTEPE------KKSQSTKPK----SL 108
+ TK A S+ T K S T+ A T E KK T PK +
Sbjct: 436 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 495
Query: 109 PKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGD 168
PK+ + T + K A + E P+ T P+ + E +A T P
Sbjct: 496 PKEPAPTTT----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP-T 550
Query: 169 KKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPM 228
+E TP P + P++P+ + AA +T P T + T P+ P
Sbjct: 551 TPEELAPTTPEEPTPTTPEEPAPTTPKAAA----PNTPKEPAPTTPKEPAPTTPKEPAPT 606
Query: 229 SSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTA 288
+ + T P K+ T P + K + P + S+ TC P
Sbjct: 607 TPK------ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTST--TCDKPAP 658
Query: 289 AGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPE 348
T K + K + T + AP T A L T +P
Sbjct: 659 T---TPKGTAPTTPKEPAPTTPKEPAP----------TTPKGTAPTTLKEPAPTTPKKP- 704
Query: 349 LDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSES 408
+ KE+ K + T P E P T K+ P P+ P +
Sbjct: 705 ----APKELAPTTTKGPTSTTSDKPAPTTPKE--TAPTTPKEPAPTTPKKPAPTTPETPP 758
Query: 409 ELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEP 464
E+S E P E T E +A P P +++++P EP
Sbjct: 759 PTTSEVSTPTTTKEPTTIHKSPDESTPE-LSAEPTPK----------ALENSPKEP 803
Score = 44.3 bits (103), Expect = 4e-04
Identities = 57/267 (21%), Positives = 93/267 (34%), Gaps = 15/267 (5%)
Query: 258 TGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQ 317
T P ++KPI P ++ S S T + T + + T Q++ +
Sbjct: 155 TSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA 214
Query: 318 EKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETI 377
++ + +EK + D A + + T +AE ++ E K E
Sbjct: 215 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 274
Query: 378 PSEYRLKPATDKDGKPL------------LPEPEEKPKPRSESELIDELSEDFDRSECKE 425
P+ + P T K+ P P ++P P + E +++ + K
Sbjct: 275 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 334
Query: 426 KPSKPTEKTEES-KAAAPAPVSEAVCRTSMCSIQSAPPEPA-TLKGTVPDDAVEALADSL 483
P+ P E + K AP E T + P EPA T K P E A +
Sbjct: 335 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-APTA 393
Query: 484 GKKEADPEDGKPVMDKVKEKAKEEDRE 510
KK A +P KE A +E
Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKE 420
Score = 43.5 bits (101), Expect = 7e-04
Identities = 109/515 (21%), Positives = 173/515 (33%), Gaps = 87/515 (16%)
Query: 86 PTETKAVKTEPEKKSQSTKPK----SLPKQASDTGSNDAH--NKKAVSRSAEQQPSEKST 139
PT KA K+ T PK + PK+ + T + K + + ++P+ +T
Sbjct: 573 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP-TT 631
Query: 140 EPKTKPQDMISAGGESVAGITAISGKP----GDKKKEKKSLTPAVPVESKPDKPSGKSGM 195
K P+++ + T P G K P P E P P G +
Sbjct: 632 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-TAP 690
Query: 196 DAALDDLIDTLGGPEETEEENTTYTGPE--VSDPMSSTYIEELGKREVTIPPKYRELLAK 253
+ T P E TT GP SD + T +E T P + K
Sbjct: 691 TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP---TTPKEPAPTTPK 747
Query: 254 KEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSA 313
K T P P +S+ T PT K + EST L A+
Sbjct: 748 KPAPTTPET-------PPPTTSEVSTPTTTKEPTTIHKSPD--ESTPELSAEPTPKALEN 798
Query: 314 AP-----PQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLE 368
+P P K K M+ A + + E DLR+ E A K K E
Sbjct: 799 SPKEPGVPTTKTPAATKPEMTTTAKDKTT----------ERDLRTTPETTTAAPKMTK-E 847
Query: 369 KCGEDDETIPSEY-----RLKPATDKDGKP----------LLPEPEEKPKPRSESELIDE 413
++T S+ ++ T +D P L P+ K + +E++++
Sbjct: 848 TATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNK 907
Query: 414 LSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ-----------SAPP 462
E+ +KP ++ SKA P P S + P
Sbjct: 908 ----------PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTP 957
Query: 463 EPATLKGTVPD-DAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET--- 518
P + T+P+ + +A+++ + P P V+ K ED G + ET
Sbjct: 958 TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ-TPNSKLVEVNPKSEDAG--GAEGETPHM 1014
Query: 519 --IPPDYRLEEVKDKDGKPLLPKESKEQLPPMSED 551
P + E D D P +P + P +S++
Sbjct: 1015 LLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDE 1049
Score = 39.3 bits (90), Expect = 0.014
Identities = 73/345 (21%), Positives = 112/345 (32%), Gaps = 47/345 (13%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
+ +P P P+ A + +P+ P + K+ A + + T
Sbjct: 624 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 683
Query: 61 YAGGTASATKVSASSGATSKSS--SMNPTETKAVKTEPEKKSQSTKPK----SLPKQASD 114
GTA T + K + + PT TK + K T PK + PK+ +
Sbjct: 684 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 743
Query: 115 TGSNDAHNKKAVSRSAEQQP---SEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKK 171
T KK + E P SE ST TK I + +S +P K
Sbjct: 744 TTP-----KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE--STPELSAEPTPKAL 796
Query: 172 EKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSST 231
E P VP P AA + T + TE + T P ++T
Sbjct: 797 ENSPKEPGVPTTKTP----------AATKPEMTTTAKDKTTERDLRT-------TPETTT 839
Query: 232 YIEELGKREVTIPPKYRE--LLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAA 289
++ K T K E + A +T + P I L + T
Sbjct: 840 AAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF----KITTLKTT-TLAPKVTT 894
Query: 290 GKKT-------EKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDT 327
KKT K E T K ++ + + PQ+ + +K T
Sbjct: 895 TKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPT 939
Score = 32.0 bits (71), Expect = 2.2
Identities = 54/255 (21%), Positives = 93/255 (36%), Gaps = 21/255 (8%)
Query: 502 EKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDF 561
E+ +E D + +K + PDY + KD K K+ PP+ + E
Sbjct: 79 ERGRECDCDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPKPPV--------VDEAG 130
Query: 562 SGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDT--SQSDKDLDDALDKLSDS 619
SG N K + VS +P TT PR + SD + +L ++
Sbjct: 131 SGLDN-GDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 189
Query: 620 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT--IPPEYRHLLDDNGQ-DKPVKPP 676
+ + NK KEK + + E+ + P + L + + K P
Sbjct: 190 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP 249
Query: 677 TKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKC----KKAASSSKAPKNGG 732
+ P ++P A + + P+T +++ T K+ K A ++ K P
Sbjct: 250 ALTTPKEPTPTTPKEP--ASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA-PT 306
Query: 733 KAKDSAKTTEETSKP 747
K+ A TT + P
Sbjct: 307 TTKEPAPTTPKEPAP 321
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 65.5 bits (158), Expect = 2e-10
Identities = 147/738 (19%), Positives = 241/738 (32%), Gaps = 83/738 (11%)
Query: 31 TSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNP---T 87
T++ S G++K + K+ S+ +T A A +KV A +++++ P T
Sbjct: 251 TNKQTSTDGKEKTTSAKETQSI-----EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 305
Query: 88 ETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQD 147
+ T P++ + +T + P + ++SA P E + P T +
Sbjct: 306 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA--PTTTKEP 363
Query: 148 MISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLG 207
+ E T +P + TP P + P KP+ + +
Sbjct: 364 APTTPKEPAPTTTK---EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE----------- 409
Query: 208 GPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKP 267
P T + T T P+ P + K PK KE PA P
Sbjct: 410 -PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-----PA----P 459
Query: 268 IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKD- 326
P + + + + +P T K T + T + P+E K+
Sbjct: 460 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 519
Query: 327 ---TMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 383
T + A T EP + KE K+ E T P E
Sbjct: 520 APTTPKEPAPTTPKKPAPTTPKEPAPT--TPKEPAPTTTKKPAPTTPKEPAPTTPKE--T 575
Query: 384 KPATDKDGKPLLPEP-----EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES- 437
P T K P PE EKP P + EL E+ P+ P E +
Sbjct: 576 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE-------PTPTTPEEPAPTTP 628
Query: 438 KAAAPAPVSEAVCRTSMCSIQSAPPEPA--TLKGTVPDDAVEALADSLGKKEADPEDGKP 495
KAAAP E T + P EPA T K T P + A + K+ A KP
Sbjct: 629 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKKP 687
Query: 496 VMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES-----KEQLPPMSE 550
++ +E +K P K P PKE KE P +
Sbjct: 688 APKELAPTTTKEPTSTTCDKPAPTTP---------KGTAPTTPKEPAPTTPKEPAPTTPK 738
Query: 551 DFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLD 610
L E P + K +LA ++ + T + P + K+
Sbjct: 739 GTAPTTLKE----PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 794
Query: 611 DALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQD 670
K P P ++ ++ H+ D++ P ++
Sbjct: 795 PTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP----DESTPELSAEPTPKALEN 850
Query: 671 KPVKP--PTKKSEDSKKPADDQDPIDALSG-DLDSCPSTTETSQNTAKDKCKKAASSSKA 727
P +P PT K+ + KP D + DL + P TT + K+ ++++
Sbjct: 851 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 910
Query: 728 PKNGGKAKDSAKTTEETS 745
+ ++ TT++T+
Sbjct: 911 KITATTTQVTSTTTQDTT 928
Score = 61.6 bits (148), Expect = 3e-09
Identities = 161/789 (20%), Positives = 258/789 (32%), Gaps = 95/789 (12%)
Query: 8 PAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTAS 67
P + P ++A + + T SP P +KK ++ + S ++S
Sbjct: 69 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 128
Query: 68 ATKVSASSG----ATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPK----QASDTGSND 119
++ S+SS +SK+S+ N K +K + KK++ TK K PK + +G ++
Sbjct: 129 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNR-TKKKPTPKPPVVDEAGSGLDN 187
Query: 120 AHNKKAVSRSAEQQPSEKSTEPK------TKPQDMISAGGE-SVAGITAISGKPGDKKKE 172
K ++ Q ++ ST PK P+ + + S ++ + + KE
Sbjct: 188 GDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKE 247
Query: 173 KKSLTPAVPVESKPDKPSGKSGMD---AALDDLIDT---LGGPEETEEENTTYTGPEVSD 226
+ + K S K + DL T L P T + TT GP ++
Sbjct: 248 TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP--TPKAETTTKGPALTT 305
Query: 227 PMSSTYIEELGKREVTIPPKYRELLAKKEGITGP--PADSSKPIGPDDAIDALSSDFTCG 284
P T K + PK K T P PA ++ P
Sbjct: 306 PKEPT--PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT------------- 350
Query: 285 SPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQ 344
+P T KE + K + T + AP K T + A T
Sbjct: 351 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT---TPKEPAPTTPKKPAPTTP 407
Query: 345 AEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKP 404
EP + KE K E P+ P T K+ P P +KP P
Sbjct: 408 KEPA--PTTPKEPTPTTPK-----------EPAPTTKEPAPTTPKEPAPTAP---KKPAP 451
Query: 405 RSESELIDELSEDFDRSECKE-KPSKPTEKTEESKAAAPAPVSE-AVCRTSMCSIQSAPP 462
+ E ++ + KE P+ P E + +AP E A T P
Sbjct: 452 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 511
Query: 463 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 522
P T K P E A + KK A +P KE A ++ + P
Sbjct: 512 SPTTTKEPAPTTPKEP-APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP- 569
Query: 523 YRLEEVKDKDGKPLLPKE----SKEQLPPMSEDFLLDALSEDF--SGPQNASSLKFED-- 574
K+ P PK+ + E+L P + + E+ + P+ + E+
Sbjct: 570 -----TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 624
Query: 575 AKLAAAISEVVSQTPASTTQAGAPPRDTSQ----SDKDLDDALDKLSDSLGQRQPDPDEN 630
A + + PA TT P + + K+ K + ++P P
Sbjct: 625 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP--T 682
Query: 631 KPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPV----KPPTKKSEDSKKP 686
P + KE A ++ D P +P K P + P
Sbjct: 683 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 742
Query: 687 ADDQDPIDAL---SGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGK-----AKDSA 738
++P + P+TT+ +T DK AP + K A
Sbjct: 743 TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 802
Query: 739 KTTEETSKP 747
TT ET P
Sbjct: 803 PTTPETPPP 811
Score = 43.5 bits (101), Expect = 7e-04
Identities = 109/515 (21%), Positives = 173/515 (33%), Gaps = 87/515 (16%)
Query: 86 PTETKAVKTEPEKKSQSTKPK----SLPKQASDTGSNDAH--NKKAVSRSAEQQPSEKST 139
PT KA K+ T PK + PK+ + T + K + + ++P+ +T
Sbjct: 625 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP-TT 683
Query: 140 EPKTKPQDMISAGGESVAGITAISGKP----GDKKKEKKSLTPAVPVESKPDKPSGKSGM 195
K P+++ + T P G K P P E P P G +
Sbjct: 684 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-TAP 742
Query: 196 DAALDDLIDTLGGPEETEEENTTYTGPE--VSDPMSSTYIEELGKREVTIPPKYRELLAK 253
+ T P E TT GP SD + T +E T P + K
Sbjct: 743 TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP---TTPKEPAPTTPK 799
Query: 254 KEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSA 313
K T P P +S+ T PT K + EST L A+
Sbjct: 800 KPAPTTPET-------PPPTTSEVSTPTTTKEPTTIHKSPD--ESTPELSAEPTPKALEN 850
Query: 314 AP-----PQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLE 368
+P P K K M+ A + + E DLR+ E A K K E
Sbjct: 851 SPKEPGVPTTKTPAATKPEMTTTAKDKTT----------ERDLRTTPETTTAAPKMTK-E 899
Query: 369 KCGEDDETIPSEY-----RLKPATDKDGKP----------LLPEPEEKPKPRSESELIDE 413
++T S+ ++ T +D P L P+ K + +E++++
Sbjct: 900 TATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNK 959
Query: 414 LSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ-----------SAPP 462
E+ +KP ++ SKA P P S + P
Sbjct: 960 ----------PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTP 1009
Query: 463 EPATLKGTVPD-DAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET--- 518
P + T+P+ + +A+++ + P P V+ K ED G + ET
Sbjct: 1010 TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ-TPNSKLVEVNPKSEDAG--GAEGETPHM 1066
Query: 519 --IPPDYRLEEVKDKDGKPLLPKESKEQLPPMSED 551
P + E D D P +P + P +S++
Sbjct: 1067 LLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDE 1101
Score = 39.3 bits (90), Expect = 0.014
Identities = 73/345 (21%), Positives = 112/345 (32%), Gaps = 47/345 (13%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
+ +P P P+ A + +P+ P + K+ A + + T
Sbjct: 676 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 735
Query: 61 YAGGTASATKVSASSGATSKSS--SMNPTETKAVKTEPEKKSQSTKPK----SLPKQASD 114
GTA T + K + + PT TK + K T PK + PK+ +
Sbjct: 736 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 795
Query: 115 TGSNDAHNKKAVSRSAEQQP---SEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKK 171
T KK + E P SE ST TK I + +S +P K
Sbjct: 796 TTP-----KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE--STPELSAEPTPKAL 848
Query: 172 EKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSST 231
E P VP P AA + T + TE + T P ++T
Sbjct: 849 ENSPKEPGVPTTKTP----------AATKPEMTTTAKDKTTERDLRT-------TPETTT 891
Query: 232 YIEELGKREVTIPPKYRE--LLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAA 289
++ K T K E + A +T + P I L + T
Sbjct: 892 AAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF----KITTLKTT-TLAPKVTT 946
Query: 290 GKKT-------EKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDT 327
KKT K E T K ++ + + PQ+ + +K T
Sbjct: 947 TKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPT 991
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 65.5 bits (158), Expect = 2e-10
Identities = 147/738 (19%), Positives = 241/738 (32%), Gaps = 83/738 (11%)
Query: 31 TSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNP---T 87
T++ S G++K + K+ S+ +T A A +KV A +++++ P T
Sbjct: 292 TNKQTSTDGKEKTTSAKETQSI-----EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 346
Query: 88 ETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQD 147
+ T P++ + +T + P + ++SA P E + P T +
Sbjct: 347 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA--PTTTKEP 404
Query: 148 MISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLG 207
+ E T +P + TP P + P KP+ + +
Sbjct: 405 APTTPKEPAPTTTK---EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE----------- 450
Query: 208 GPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKP 267
P T + T T P+ P + K PK KE PA P
Sbjct: 451 -PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-----PA----P 500
Query: 268 IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKD- 326
P + + + + +P T K T + T + P+E K+
Sbjct: 501 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 560
Query: 327 ---TMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 383
T + A T EP + KE K+ E T P E
Sbjct: 561 APTTPKEPAPTTPKKPAPTTPKEPAPT--TPKEPAPTTTKKPAPTTPKEPAPTTPKE--T 616
Query: 384 KPATDKDGKPLLPEP-----EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES- 437
P T K P PE EKP P + EL E+ P+ P E +
Sbjct: 617 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE-------PTPTTPEEPAPTTP 669
Query: 438 KAAAPAPVSEAVCRTSMCSIQSAPPEPA--TLKGTVPDDAVEALADSLGKKEADPEDGKP 495
KAAAP E T + P EPA T K T P + A + K+ A KP
Sbjct: 670 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKKP 728
Query: 496 VMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES-----KEQLPPMSE 550
++ +E +K P K P PKE KE P +
Sbjct: 729 APKELAPTTTKEPTSTTCDKPAPTTP---------KGTAPTTPKEPAPTTPKEPAPTTPK 779
Query: 551 DFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLD 610
L E P + K +LA ++ + T + P + K+
Sbjct: 780 GTAPTTLKE----PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 835
Query: 611 DALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQD 670
K P P ++ ++ H+ D++ P ++
Sbjct: 836 PTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP----DESTPELSAEPTPKALEN 891
Query: 671 KPVKP--PTKKSEDSKKPADDQDPIDALSG-DLDSCPSTTETSQNTAKDKCKKAASSSKA 727
P +P PT K+ + KP D + DL + P TT + K+ ++++
Sbjct: 892 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 951
Query: 728 PKNGGKAKDSAKTTEETS 745
+ ++ TT++T+
Sbjct: 952 KITATTTQVTSTTTQDTT 969
Score = 61.6 bits (148), Expect = 3e-09
Identities = 161/789 (20%), Positives = 258/789 (32%), Gaps = 95/789 (12%)
Query: 8 PAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTAS 67
P + P ++A + + T SP P +KK ++ + S ++S
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 169
Query: 68 ATKVSASSG----ATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPK----QASDTGSND 119
++ S+SS +SK+S+ N K +K + KK++ TK K PK + +G ++
Sbjct: 170 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNR-TKKKPTPKPPVVDEAGSGLDN 228
Query: 120 AHNKKAVSRSAEQQPSEKSTEPK------TKPQDMISAGGE-SVAGITAISGKPGDKKKE 172
K ++ Q ++ ST PK P+ + + S ++ + + KE
Sbjct: 229 GDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKE 288
Query: 173 KKSLTPAVPVESKPDKPSGKSGMD---AALDDLIDT---LGGPEETEEENTTYTGPEVSD 226
+ + K S K + DL T L P T + TT GP ++
Sbjct: 289 TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP--TPKAETTTKGPALTT 346
Query: 227 PMSSTYIEELGKREVTIPPKYRELLAKKEGITGP--PADSSKPIGPDDAIDALSSDFTCG 284
P T K + PK K T P PA ++ P
Sbjct: 347 PKEPT--PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT------------- 391
Query: 285 SPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQ 344
+P T KE + K + T + AP K T + A T
Sbjct: 392 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT---TPKEPAPTTPKKPAPTTP 448
Query: 345 AEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKP 404
EP + KE K E P+ P T K+ P P +KP P
Sbjct: 449 KEPA--PTTPKEPTPTTPK-----------EPAPTTKEPAPTTPKEPAPTAP---KKPAP 492
Query: 405 RSESELIDELSEDFDRSECKE-KPSKPTEKTEESKAAAPAPVSE-AVCRTSMCSIQSAPP 462
+ E ++ + KE P+ P E + +AP E A T P
Sbjct: 493 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 552
Query: 463 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 522
P T K P E A + KK A +P KE A ++ + P
Sbjct: 553 SPTTTKEPAPTTPKEP-APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP- 610
Query: 523 YRLEEVKDKDGKPLLPKE----SKEQLPPMSEDFLLDALSEDF--SGPQNASSLKFED-- 574
K+ P PK+ + E+L P + + E+ + P+ + E+
Sbjct: 611 -----TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 665
Query: 575 AKLAAAISEVVSQTPASTTQAGAPPRDTSQ----SDKDLDDALDKLSDSLGQRQPDPDEN 630
A + + PA TT P + + K+ K + ++P P
Sbjct: 666 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP--T 723
Query: 631 KPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPV----KPPTKKSEDSKKP 686
P + KE A ++ D P +P K P + P
Sbjct: 724 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 783
Query: 687 ADDQDPIDAL---SGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGK-----AKDSA 738
++P + P+TT+ +T DK AP + K A
Sbjct: 784 TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 843
Query: 739 KTTEETSKP 747
TT ET P
Sbjct: 844 PTTPETPPP 852
Score = 43.5 bits (101), Expect = 7e-04
Identities = 109/515 (21%), Positives = 173/515 (33%), Gaps = 87/515 (16%)
Query: 86 PTETKAVKTEPEKKSQSTKPK----SLPKQASDTGSNDAH--NKKAVSRSAEQQPSEKST 139
PT KA K+ T PK + PK+ + T + K + + ++P+ +T
Sbjct: 666 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP-TT 724
Query: 140 EPKTKPQDMISAGGESVAGITAISGKP----GDKKKEKKSLTPAVPVESKPDKPSGKSGM 195
K P+++ + T P G K P P E P P G +
Sbjct: 725 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG-TAP 783
Query: 196 DAALDDLIDTLGGPEETEEENTTYTGPE--VSDPMSSTYIEELGKREVTIPPKYRELLAK 253
+ T P E TT GP SD + T +E T P + K
Sbjct: 784 TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP---TTPKEPAPTTPK 840
Query: 254 KEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSA 313
K T P P +S+ T PT K + EST L A+
Sbjct: 841 KPAPTTPET-------PPPTTSEVSTPTTTKEPTTIHKSPD--ESTPELSAEPTPKALEN 891
Query: 314 AP-----PQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLE 368
+P P K K M+ A + + E DLR+ E A K K E
Sbjct: 892 SPKEPGVPTTKTPAATKPEMTTTAKDKTT----------ERDLRTTPETTTAAPKMTK-E 940
Query: 369 KCGEDDETIPSEY-----RLKPATDKDGKP----------LLPEPEEKPKPRSESELIDE 413
++T S+ ++ T +D P L P+ K + +E++++
Sbjct: 941 TATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNK 1000
Query: 414 LSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ-----------SAPP 462
E+ +KP ++ SKA P P S + P
Sbjct: 1001 ----------PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTP 1050
Query: 463 EPATLKGTVPD-DAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET--- 518
P + T+P+ + +A+++ + P P V+ K ED G + ET
Sbjct: 1051 TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ-TPNSKLVEVNPKSEDAG--GAEGETPHM 1107
Query: 519 --IPPDYRLEEVKDKDGKPLLPKESKEQLPPMSED 551
P + E D D P +P + P +S++
Sbjct: 1108 LLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDE 1142
Score = 39.3 bits (90), Expect = 0.014
Identities = 73/345 (21%), Positives = 112/345 (32%), Gaps = 47/345 (13%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
+ +P P P+ A + +P+ P + K+ A + + T
Sbjct: 717 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 776
Query: 61 YAGGTASATKVSASSGATSKSS--SMNPTETKAVKTEPEKKSQSTKPK----SLPKQASD 114
GTA T + K + + PT TK + K T PK + PK+ +
Sbjct: 777 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 836
Query: 115 TGSNDAHNKKAVSRSAEQQP---SEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKK 171
T KK + E P SE ST TK I + +S +P K
Sbjct: 837 TTP-----KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE--STPELSAEPTPKAL 889
Query: 172 EKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSST 231
E P VP P AA + T + TE + T P ++T
Sbjct: 890 ENSPKEPGVPTTKTP----------AATKPEMTTTAKDKTTERDLRT-------TPETTT 932
Query: 232 YIEELGKREVTIPPKYRE--LLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAA 289
++ K T K E + A +T + P I L + T
Sbjct: 933 AAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF----KITTLKTT-TLAPKVTT 987
Query: 290 GKKT-------EKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDT 327
KKT K E T K ++ + + PQ+ + +K T
Sbjct: 988 TKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPT 1032
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 65.1 bits (157), Expect = 2e-10
Identities = 159/767 (20%), Positives = 288/767 (37%), Gaps = 137/767 (17%)
Query: 8 PAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSS---QSSRTYAGG 64
P SP+P+ + RR ++ T S+P + + K G+S Q+S +
Sbjct: 892 PQQSPKPQEQS--RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTA 949
Query: 65 TASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKK 124
+ GA K + P ++ ++ KS P + K A +
Sbjct: 950 GQPGPHSQSGPGAPMKQA---PAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAE 1006
Query: 125 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVE- 183
+ AEQ P+ K TE + KP + + + A+ +K + +S P E
Sbjct: 1007 KLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTEL 1066
Query: 184 --SKPDKPSGKSGMDAA--LDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKR 239
D P+ + + + +L P TE + + +S +LG
Sbjct: 1067 NIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISG----QLGD- 1121
Query: 240 EVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAA-GKKTEKEES 298
R++ PPA S P SS T P KK E+E
Sbjct: 1122 -------IRKM---------PPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVK 1165
Query: 299 TE----VLKAQSAGTVRSAAPP------QEKKRKVEKDTMSDQALEALSASLGTRQAEPE 348
TE +L+ PP ++++ K+EKD S +L ++ PE
Sbjct: 1166 TEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKAS---------ALQEKKPLPE 1216
Query: 349 LDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSES 408
+ + I E ++ +++E+K E+ + P + +L P + K PE ++ +S+
Sbjct: 1217 -EKKLIPEEEKIRSEEKK--PLLEEKKPTPEDKKLLP----EAKTSAPEEQKHDLLKSQV 1269
Query: 409 ELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLK 468
++ +E E + ++ +P K E + P + + +T+ +I+ P P T K
Sbjct: 1270 QIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTK-TIKEQPQPPCTAK 1328
Query: 469 GTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEV 528
D VE GK++ + ED K ++ + G + I L E+
Sbjct: 1329 ----PDQVEP-----GKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSS--LGEI 1377
Query: 529 KDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQT 588
L+P + K+ L + +D + S++ S P + S L AKL + + ++ +
Sbjct: 1378 PS-----LIPTDEKDILKGLKKD----SFSQE-SSPSSPSDL----AKLESTVLSIL-EA 1422
Query: 589 PASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKA----- 643
AST L+D +++ P E P + K +EK ++
Sbjct: 1423 QAST-----------------------LADEKSEKKTQPHEVSPEQPKDQEKTQSLSETL 1459
Query: 644 -------EHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDAL 696
E ++ ER DT D+ QD P S+D K+ ++ D I
Sbjct: 1460 EITISEEEIKESQEERKDTFK-------KDSQQDIP------SSKDHKEKSEFVDDITTR 1506
Query: 697 SGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 743
DS ++E S+N+ + K+ S + + K +DS + EE
Sbjct: 1507 REPYDSVEESSE-SENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEE 1552
Score = 60.5 bits (145), Expect = 6e-09
Identities = 130/599 (21%), Positives = 212/599 (35%), Gaps = 75/599 (12%)
Query: 4 PGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQ--SSRTY 61
P Q A P P++ +A+ + T P +PG K S ++ ++ SQ S
Sbjct: 481 PQQPGPAKPPPQQPGSAKPPSQQPGS-TKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP 539
Query: 62 AGGTASATKVSA--SSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSL----------- 108
+ S K SA S+ S++ S P + V ++ PK++
Sbjct: 540 SAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLL 599
Query: 109 --PKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPK----TKPQDMISAGGESVAGITAI 162
P++A+ + + V P+ TE K Q + GG+ + +
Sbjct: 600 HVPEKANFNTCTEC--QTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGD----LAPV 653
Query: 163 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEE--ENTTYT 220
P K K T + +S P DAA + P++ + T
Sbjct: 654 PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
Query: 221 GPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGP---DDAIDAL 277
G + + L K PPK E E P AD KP P D +
Sbjct: 714 GSPSAKAKQPPEADSLSK---PAPPK--EPSVPSEQDKAPVAD-DKPKQPKMVKPTTDLV 767
Query: 278 SSDFTCGSPTAAGKKTE---KEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALE 334
SS P K + +E++T LK SA +S P EK + + A +
Sbjct: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
Query: 335 ALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGE-----DDETIPSEYRLKPATDK 389
+ S P + + K+VD + KEE + + D + +P P
Sbjct: 828 SKIIS----HPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883
Query: 390 DGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEE------------- 436
+P P++ PKP+ +S L+ K +P+ P E
Sbjct: 884 TAGQTVPTPQQSPKPQEQSRRF-SLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQA 942
Query: 437 ----SKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPD--DAVEALADSLGKKEADP 490
S A P P S++ M AP +P T +G A A A S+ K+
Sbjct: 943 SNLISTAGQPGPHSQSGPGAPM-KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKK--- 998
Query: 491 EDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMS 549
E P +K++ KA++ K E E+ PP + + + K +LP + ++ P S
Sbjct: 999 ETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPES 1057
Score = 58.9 bits (141), Expect = 2e-08
Identities = 181/839 (21%), Positives = 286/839 (34%), Gaps = 144/839 (17%)
Query: 10 ASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSR-------TYA 62
+SP+P+ A T VS K+S P + KK + K+ S T
Sbjct: 655 SSPQPKLKTAPVTTTSAVS-KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
Query: 63 GGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDT----GSN 118
G ++ K + + SK + P + +V +E +K + PK T S+
Sbjct: 714 GSPSAKAKQPPEADSLSKPA---PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS 770
Query: 119 DAHNKKAVSRSAEQQPSEKSTEP-----KTKPQDMISAGGESVAGIT--AISGKPGDKK- 170
A K + S Q +E+ T P KP GE V+ AI D K
Sbjct: 771 SATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKI 830
Query: 171 -------KEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPE 223
E K PV+ K + ++ M D G P T G
Sbjct: 831 ISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA--GQT 888
Query: 224 VSDPMSSTYIEELGKR------EVTIPPKYRELLAKKEGITGP----------------- 260
V P S +E +R +T PK + +E +TG
Sbjct: 889 VPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT-TPQETVTGKLFGFGASIFSQASNLIS 947
Query: 261 ------PADSSKPIGPDDAIDALSSDFTC-GSPTAAG------------KKTEKEESTEV 301
P S P P A S T G P + G KK K + E
Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007
Query: 302 L--KAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQ------------AEP 347
L KA+ A TV+ EKK KD+ S A E A L T+ +
Sbjct: 1008 LEPKAEQAPTVKRTET--EKKPPPIKDSKSLTA-EPQKAVLPTKLEKSPKPESTCPLCKT 1064
Query: 348 ELDLRSIKEVDEAKAKEEKLEKCG-----------EDDETIPSEYRLKPATDKDGKPLLP 396
EL++ S + E K + C E E + + + A +
Sbjct: 1065 ELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRK 1124
Query: 397 EPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCS 456
P P++ + S ++ + ++ +E K A + E V T S
Sbjct: 1125 MPPAPSGPKASPMPVPTESSS-QKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKET--LS 1181
Query: 457 IQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKE 516
++ PP T + + A +L +K+ PE+ K + ++ EK + E+++ L E++
Sbjct: 1182 MEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEE--EKIRSEEKKPLLEEK 1239
Query: 517 ETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAK 576
+ P D K LLP E+K P + LL S ++ + K
Sbjct: 1240 KPTPED-----------KKLLP-EAKTSAPEEQKHDLL------------KSQVQIAEEK 1275
Query: 577 LAAAIS-EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMED 635
L ++ + V + T+ P T QS DD K + QP P +
Sbjct: 1276 LEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTI----KEQPQPPCTAKPDQ 1331
Query: 636 KVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDA 695
K K E D + + P+ L D G + S P D++D +
Sbjct: 1332 VEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKG 1391
Query: 696 LSGDLDSCPSTTETSQNTAKDKCK-----KAASSSKAPKNGGKAKDSAKTTEETSKPKD 749
L D S S+ + + AK + +A +S+ A + K + + E +PKD
Sbjct: 1392 LKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPE--QPKD 1448
Score = 51.6 bits (122), Expect = 3e-06
Identities = 102/564 (18%), Positives = 202/564 (35%), Gaps = 62/564 (10%)
Query: 19 AARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGAT 78
A + V+ KT + +P K + G+ QS T K T
Sbjct: 1272 AEEKLEGRVAPKTVQEGKQPQTKM-----EGLPSGTPQSLPKEDDKTTKTIKEQPQPPCT 1326
Query: 79 SKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKS 138
+K + P + K K + + + S++ P+ SDTG ++ +S S + PS
Sbjct: 1327 AKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTG----YSSDGISSSLGEIPSLIP 1382
Query: 139 TEPK-----------------TKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVP 181
T+ K + P D+ ++ + A + D+K EKK+ V
Sbjct: 1383 TDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVS 1442
Query: 182 VESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMS-------STYIE 234
E D+ +S + L+ I E EE T+ D S S +++
Sbjct: 1443 PEQPKDQEKTQS-LSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVD 1501
Query: 235 ELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTE 294
++ R P E ++ E P +G + + D + G E
Sbjct: 1502 DITTRRE--PYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQED-------SQGSGEE 1552
Query: 295 KEESTEVLKAQSAGTVRSAAPPQE----KKRKVEKDTMSDQALEALSASLGTRQAEPELD 350
++ + + SA S + E + +++ T S + E T L
Sbjct: 1553 EDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLT 1612
Query: 351 LRSIKEVDEAKAKEEKLEKCGEDDETIPS--EYRLKPATDKDGKPLLPEPEEKPKPRSES 408
+S +DE + EDDE E + + ++ + L+ +
Sbjct: 1613 RKSSTSIDEDAGRRHSWH--DEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTI 1670
Query: 409 ELIDELSEDFDRSECKEKPS----KPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEP 464
EL +++ + ++K S + E ES +P S +S+ + P
Sbjct: 1671 ELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTS 1730
Query: 465 ATLKGTVPDDAVEALADSLG----KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIP 520
T ++ +D+ + + G +++A P++ +++ ++EE+ L E+EE +
Sbjct: 1731 PTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEE---LREEEELLK 1787
Query: 521 PDYRLEEVKDKDGKPLLPKESKEQ 544
+ E++ + K K K++
Sbjct: 1788 EQEKQREIEQQQRKSSSKKSKKDK 1811
Score = 43.9 bits (102), Expect = 5e-04
Identities = 150/761 (19%), Positives = 253/761 (33%), Gaps = 104/761 (13%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSK----------------------- 37
+ P + P P P + A + HE ++ P++
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPG 357
Query: 38 ----PGEKKGSDEKKAASLGSSQSSRTYAGGTASAT-----KVSASSGATSKSSSMNPTE 88
P + G + A GS + S G A A K A +K +
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT 417
Query: 89 TKAVKTEP--EKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQ-----QPSEKSTEP 141
K + +P + +++ P P Q G A SA+Q PS+
Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA 477
Query: 142 KTKPQDMISA-------GGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSG 194
K PQ A G S KP ++ +P P +KP S
Sbjct: 478 KPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537
Query: 195 MDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKK 254
+A + T+ + T +G + P S ++ + +P L
Sbjct: 538 KPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ--GLPKTICPLCNTT 595
Query: 255 EGITGPPAD--------------SSKPIGPDDAIDALSS--DFTCGSPTAAGKKTEKEES 298
E + P S P+ + + C A G S
Sbjct: 596 ELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655
Query: 299 TEVLKAQSAGTVRSAA----PPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSI 354
+ K ++A ++A PQ ++ +KD Q LS + ++ P + ++
Sbjct: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ---DLSKAPEPKKPPPLVKQPTL 712
Query: 355 KEVDEAKAKE----EKLEKCGEDDE-TIPSEYRLKP-ATDKDGKPLLPEPEEKPKPRSES 408
AKAK+ + L K E ++PSE P A DK +P + +P S +
Sbjct: 713 HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSA 772
Query: 409 ELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLK 468
++ +S+ +EK + P + + + P E V A P PA+
Sbjct: 773 TTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD----SKAIPRPASDS 828
Query: 469 GTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEV 528
+ ++S G+K+ DP K K + K + K K PP R
Sbjct: 829 KIISHPGPS--SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAG 886
Query: 529 KDKDGKPLLPK-ESKEQLPPMSEDFLLDALSEDFSGPQNASSLKF--EDAKLAAAISEVV 585
+ PK + + + ++ + DA + PQ + K A + + S ++
Sbjct: 887 QTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLI 946
Query: 586 SQT----PASTTQAGAPPRDT-SQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEK 640
S P S + GAP + + S K S GQ P P ++ P VK++
Sbjct: 947 STAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK---STGQAPPAPAKSIP----VKKE 999
Query: 641 AKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSE 681
KA +KL + + P R + KP PP K S+
Sbjct: 1000 TKAPAAEKLEPKAEQAPTVKR----TETEKKP--PPIKDSK 1034
Score = 39.3 bits (90), Expect = 0.014
Identities = 162/869 (18%), Positives = 268/869 (30%), Gaps = 181/869 (20%)
Query: 2 SQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGS----DEKKAASLGSSQS 57
S P ++ P P R A + ++ PG + + K L
Sbjct: 90 SHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHK 149
Query: 58 SRTYAGGTASATKVSASSGATSKSSSMNP-TETKAVKTEPEKKS---------------- 100
S G + +SA S +K + + ++++A + E KK
Sbjct: 150 SSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKP 209
Query: 101 --QSTKPKSLPKQAS---DTGSNDAHNKKAVSRSAEQQPSEK------------------ 137
Q PK +PKQ D D K S+ E+ S+
Sbjct: 210 PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269
Query: 138 --------STEPKTKPQDMISAGGESVAGITAISGKPGDKKK------------EKKSLT 177
++ P+TK D++ GESV KP ++ EK
Sbjct: 270 AKLPLQRDASRPQTKQADIVR--GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPG 327
Query: 178 PAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSST-----Y 232
PA P P +PSG + A + P T + GP P T
Sbjct: 328 PAKP----PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGP-AKPPAQQTGSEKPS 382
Query: 233 IEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAA--- 289
E+ G + + PP + A++ G PP P L S PT
Sbjct: 383 SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442
Query: 290 ----GKKTEKEESTEVLKAQSAGTVRS-------AAPPQEKKRKVEKDTMSDQALEALSA 338
GK ++ AQ G + A PP ++ + + + S
Sbjct: 443 QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 339 SLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEP 398
G+ + P+ + + + + ++ G + KP+ + KP+
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562
Query: 399 EEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVC---RTS 453
KP P S+ ++ C P T E P + C +T+
Sbjct: 563 SGKPLQPPTVSPSAKQPPSQGLPKTIC------PLCNTTELLLHVPEKANFNTCTECQTT 616
Query: 454 MCSIQSAPPEP------------ATLKGTVPDD--------------AVEALADSLGKKE 487
+CS+ P P +K + D A ++ K
Sbjct: 617 VCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSS 676
Query: 488 ADPEDGKPVMDKVKEKAKEEDREKLGEKEETIP----------PDYRLEEVKDKDG--KP 535
P+ P K+ A ++D K E ++ P P + ++ + D KP
Sbjct: 677 PQPQQTSPK----KDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP 732
Query: 536 LLPKE----SKEQLPPMSEDF-----LLDALSEDFSGPQNASSLKFEDAKLAAAISEVVS 586
PKE S++ P+++D ++ ++ S + +K+ + E
Sbjct: 733 APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE--K 790
Query: 587 QTPASTTQAGAP------------PRDTSQ-----SDKDLDDALDKLSDSLGQRQPDPDE 629
TP T + P P D+ SD + S+S GQ+Q DP +
Sbjct: 791 TTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQ 850
Query: 630 NKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADD 689
K K + K + K + PP R GQ P + S KP +
Sbjct: 851 KKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPR---PTAGQTVPT------PQQSPKPQEQ 901
Query: 690 QDPIDALSGDLDSCP-STTETSQNTAKDK 717
G + P S T Q T K
Sbjct: 902 SRRFSLNLGSITDAPKSQPTTPQETVTGK 930
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 65.1 bits (157), Expect = 2e-10
Identities = 159/767 (20%), Positives = 288/767 (37%), Gaps = 137/767 (17%)
Query: 8 PAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSS---QSSRTYAGG 64
P SP+P+ + RR ++ T S+P + + K G+S Q+S +
Sbjct: 892 PQQSPKPQEQS--RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTA 949
Query: 65 TASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKK 124
+ GA K + P ++ ++ KS P + K A +
Sbjct: 950 GQPGPHSQSGPGAPMKQA---PAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAE 1006
Query: 125 AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVE- 183
+ AEQ P+ K TE + KP + + + A+ +K + +S P E
Sbjct: 1007 KLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTEL 1066
Query: 184 --SKPDKPSGKSGMDAA--LDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKR 239
D P+ + + + +L P TE + + +S +LG
Sbjct: 1067 NIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISG----QLGD- 1121
Query: 240 EVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAA-GKKTEKEES 298
R++ PPA S P SS T P KK E+E
Sbjct: 1122 -------IRKM---------PPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVK 1165
Query: 299 TE----VLKAQSAGTVRSAAPP------QEKKRKVEKDTMSDQALEALSASLGTRQAEPE 348
TE +L+ PP ++++ K+EKD S +L ++ PE
Sbjct: 1166 TEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKAS---------ALQEKKPLPE 1216
Query: 349 LDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSES 408
+ + I E ++ +++E+K E+ + P + +L P + K PE ++ +S+
Sbjct: 1217 -EKKLIPEEEKIRSEEKK--PLLEEKKPTPEDKKLLP----EAKTSAPEEQKHDLLKSQV 1269
Query: 409 ELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLK 468
++ +E E + ++ +P K E + P + + +T+ +I+ P P T K
Sbjct: 1270 QIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTK-TIKEQPQPPCTAK 1328
Query: 469 GTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEV 528
D VE GK++ + ED K ++ + G + I L E+
Sbjct: 1329 ----PDQVEP-----GKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSS--LGEI 1377
Query: 529 KDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQT 588
L+P + K+ L + +D + S++ S P + S L AKL + + ++ +
Sbjct: 1378 PS-----LIPTDEKDILKGLKKD----SFSQE-SSPSSPSDL----AKLESTVLSIL-EA 1422
Query: 589 PASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKA----- 643
AST L+D +++ P E P + K +EK ++
Sbjct: 1423 QAST-----------------------LADEKSEKKTQPHEVSPEQPKDQEKTQSLSETL 1459
Query: 644 -------EHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDAL 696
E ++ ER DT D+ QD P S+D K+ ++ D I
Sbjct: 1460 EITISEEEIKESQEERKDTFK-------KDSQQDIP------SSKDHKEKSEFVDDITTR 1506
Query: 697 SGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 743
DS ++E S+N+ + K+ S + + K +DS + EE
Sbjct: 1507 REPYDSVEESSE-SENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEE 1552
Score = 60.5 bits (145), Expect = 6e-09
Identities = 130/599 (21%), Positives = 212/599 (35%), Gaps = 75/599 (12%)
Query: 4 PGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQ--SSRTY 61
P Q A P P++ +A+ + T P +PG K S ++ ++ SQ S
Sbjct: 481 PQQPGPAKPPPQQPGSAKPPSQQPGS-TKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP 539
Query: 62 AGGTASATKVSA--SSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSL----------- 108
+ S K SA S+ S++ S P + V ++ PK++
Sbjct: 540 SAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLL 599
Query: 109 --PKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPK----TKPQDMISAGGESVAGITAI 162
P++A+ + + V P+ TE K Q + GG+ + +
Sbjct: 600 HVPEKANFNTCTEC--QTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGD----LAPV 653
Query: 163 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEE--ENTTYT 220
P K K T + +S P DAA + P++ + T
Sbjct: 654 PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
Query: 221 GPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGP---DDAIDAL 277
G + + L K PPK E E P AD KP P D +
Sbjct: 714 GSPSAKAKQPPEADSLSK---PAPPK--EPSVPSEQDKAPVAD-DKPKQPKMVKPTTDLV 767
Query: 278 SSDFTCGSPTAAGKKTE---KEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALE 334
SS P K + +E++T LK SA +S P EK + + A +
Sbjct: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
Query: 335 ALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGE-----DDETIPSEYRLKPATDK 389
+ S P + + K+VD + KEE + + D + +P P
Sbjct: 828 SKIIS----HPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883
Query: 390 DGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEE------------- 436
+P P++ PKP+ +S L+ K +P+ P E
Sbjct: 884 TAGQTVPTPQQSPKPQEQSRRF-SLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQA 942
Query: 437 ----SKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPD--DAVEALADSLGKKEADP 490
S A P P S++ M AP +P T +G A A A S+ K+
Sbjct: 943 SNLISTAGQPGPHSQSGPGAPM-KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKK--- 998
Query: 491 EDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMS 549
E P +K++ KA++ K E E+ PP + + + K +LP + ++ P S
Sbjct: 999 ETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPES 1057
Score = 58.9 bits (141), Expect = 2e-08
Identities = 181/839 (21%), Positives = 286/839 (34%), Gaps = 144/839 (17%)
Query: 10 ASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSR-------TYA 62
+SP+P+ A T VS K+S P + KK + K+ S T
Sbjct: 655 SSPQPKLKTAPVTTTSAVS-KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
Query: 63 GGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDT----GSN 118
G ++ K + + SK + P + +V +E +K + PK T S+
Sbjct: 714 GSPSAKAKQPPEADSLSKPA---PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS 770
Query: 119 DAHNKKAVSRSAEQQPSEKSTEP-----KTKPQDMISAGGESVAGIT--AISGKPGDKK- 170
A K + S Q +E+ T P KP GE V+ AI D K
Sbjct: 771 SATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKI 830
Query: 171 -------KEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPE 223
E K PV+ K + ++ M D G P T G
Sbjct: 831 ISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA--GQT 888
Query: 224 VSDPMSSTYIEELGKR------EVTIPPKYRELLAKKEGITGP----------------- 260
V P S +E +R +T PK + +E +TG
Sbjct: 889 VPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT-TPQETVTGKLFGFGASIFSQASNLIS 947
Query: 261 ------PADSSKPIGPDDAIDALSSDFTC-GSPTAAG------------KKTEKEESTEV 301
P S P P A S T G P + G KK K + E
Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007
Query: 302 L--KAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQ------------AEP 347
L KA+ A TV+ EKK KD+ S A E A L T+ +
Sbjct: 1008 LEPKAEQAPTVKRTET--EKKPPPIKDSKSLTA-EPQKAVLPTKLEKSPKPESTCPLCKT 1064
Query: 348 ELDLRSIKEVDEAKAKEEKLEKCG-----------EDDETIPSEYRLKPATDKDGKPLLP 396
EL++ S + E K + C E E + + + A +
Sbjct: 1065 ELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRK 1124
Query: 397 EPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCS 456
P P++ + S ++ + ++ +E K A + E V T S
Sbjct: 1125 MPPAPSGPKASPMPVPTESSS-QKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKET--LS 1181
Query: 457 IQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKE 516
++ PP T + + A +L +K+ PE+ K + ++ EK + E+++ L E++
Sbjct: 1182 MEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEE--EKIRSEEKKPLLEEK 1239
Query: 517 ETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAK 576
+ P D K LLP E+K P + LL S ++ + K
Sbjct: 1240 KPTPED-----------KKLLP-EAKTSAPEEQKHDLL------------KSQVQIAEEK 1275
Query: 577 LAAAIS-EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMED 635
L ++ + V + T+ P T QS DD K + QP P +
Sbjct: 1276 LEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTI----KEQPQPPCTAKPDQ 1331
Query: 636 KVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDA 695
K K E D + + P+ L D G + S P D++D +
Sbjct: 1332 VEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKG 1391
Query: 696 LSGDLDSCPSTTETSQNTAKDKCK-----KAASSSKAPKNGGKAKDSAKTTEETSKPKD 749
L D S S+ + + AK + +A +S+ A + K + + E +PKD
Sbjct: 1392 LKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPE--QPKD 1448
Score = 51.6 bits (122), Expect = 3e-06
Identities = 102/564 (18%), Positives = 202/564 (35%), Gaps = 62/564 (10%)
Query: 19 AARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGAT 78
A + V+ KT + +P K + G+ QS T K T
Sbjct: 1272 AEEKLEGRVAPKTVQEGKQPQTKM-----EGLPSGTPQSLPKEDDKTTKTIKEQPQPPCT 1326
Query: 79 SKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKS 138
+K + P + K K + + + S++ P+ SDTG ++ +S S + PS
Sbjct: 1327 AKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTG----YSSDGISSSLGEIPSLIP 1382
Query: 139 TEPK-----------------TKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVP 181
T+ K + P D+ ++ + A + D+K EKK+ V
Sbjct: 1383 TDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVS 1442
Query: 182 VESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMS-------STYIE 234
E D+ +S + L+ I E EE T+ D S S +++
Sbjct: 1443 PEQPKDQEKTQS-LSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVD 1501
Query: 235 ELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTE 294
++ R P E ++ E P +G + + D + G E
Sbjct: 1502 DITTRRE--PYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQED-------SQGSGEE 1552
Query: 295 KEESTEVLKAQSAGTVRSAAPPQE----KKRKVEKDTMSDQALEALSASLGTRQAEPELD 350
++ + + SA S + E + +++ T S + E T L
Sbjct: 1553 EDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLT 1612
Query: 351 LRSIKEVDEAKAKEEKLEKCGEDDETIPS--EYRLKPATDKDGKPLLPEPEEKPKPRSES 408
+S +DE + EDDE E + + ++ + L+ +
Sbjct: 1613 RKSSTSIDEDAGRRHSWH--DEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTI 1670
Query: 409 ELIDELSEDFDRSECKEKPS----KPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEP 464
EL +++ + ++K S + E ES +P S +S+ + P
Sbjct: 1671 ELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTS 1730
Query: 465 ATLKGTVPDDAVEALADSLG----KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIP 520
T ++ +D+ + + G +++A P++ +++ ++EE+ L E+EE +
Sbjct: 1731 PTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEE---LREEEELLK 1787
Query: 521 PDYRLEEVKDKDGKPLLPKESKEQ 544
+ E++ + K K K++
Sbjct: 1788 EQEKQREIEQQQRKSSSKKSKKDK 1811
Score = 43.9 bits (102), Expect = 5e-04
Identities = 150/761 (19%), Positives = 253/761 (33%), Gaps = 104/761 (13%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSK----------------------- 37
+ P + P P P + A + HE ++ P++
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPG 357
Query: 38 ----PGEKKGSDEKKAASLGSSQSSRTYAGGTASAT-----KVSASSGATSKSSSMNPTE 88
P + G + A GS + S G A A K A +K +
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT 417
Query: 89 TKAVKTEP--EKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQ-----QPSEKSTEP 141
K + +P + +++ P P Q G A SA+Q PS+
Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA 477
Query: 142 KTKPQDMISA-------GGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSG 194
K PQ A G S KP ++ +P P +KP S
Sbjct: 478 KPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537
Query: 195 MDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKK 254
+A + T+ + T +G + P S ++ + +P L
Sbjct: 538 KPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ--GLPKTICPLCNTT 595
Query: 255 EGITGPPAD--------------SSKPIGPDDAIDALSS--DFTCGSPTAAGKKTEKEES 298
E + P S P+ + + C A G S
Sbjct: 596 ELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655
Query: 299 TEVLKAQSAGTVRSAA----PPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSI 354
+ K ++A ++A PQ ++ +KD Q LS + ++ P + ++
Sbjct: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ---DLSKAPEPKKPPPLVKQPTL 712
Query: 355 KEVDEAKAKE----EKLEKCGEDDE-TIPSEYRLKP-ATDKDGKPLLPEPEEKPKPRSES 408
AKAK+ + L K E ++PSE P A DK +P + +P S +
Sbjct: 713 HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSA 772
Query: 409 ELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLK 468
++ +S+ +EK + P + + + P E V A P PA+
Sbjct: 773 TTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD----SKAIPRPASDS 828
Query: 469 GTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEV 528
+ ++S G+K+ DP K K + K + K K PP R
Sbjct: 829 KIISHPGPS--SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAG 886
Query: 529 KDKDGKPLLPK-ESKEQLPPMSEDFLLDALSEDFSGPQNASSLKF--EDAKLAAAISEVV 585
+ PK + + + ++ + DA + PQ + K A + + S ++
Sbjct: 887 QTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLI 946
Query: 586 SQT----PASTTQAGAPPRDT-SQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEK 640
S P S + GAP + + S K S GQ P P ++ P VK++
Sbjct: 947 STAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK---STGQAPPAPAKSIP----VKKE 999
Query: 641 AKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSE 681
KA +KL + + P R + KP PP K S+
Sbjct: 1000 TKAPAAEKLEPKAEQAPTVKR----TETEKKP--PPIKDSK 1034
Score = 39.3 bits (90), Expect = 0.014
Identities = 162/869 (18%), Positives = 268/869 (30%), Gaps = 181/869 (20%)
Query: 2 SQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGS----DEKKAASLGSSQS 57
S P ++ P P R A + ++ PG + + K L
Sbjct: 90 SHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHK 149
Query: 58 SRTYAGGTASATKVSASSGATSKSSSMNP-TETKAVKTEPEKKS---------------- 100
S G + +SA S +K + + ++++A + E KK
Sbjct: 150 SSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKP 209
Query: 101 --QSTKPKSLPKQAS---DTGSNDAHNKKAVSRSAEQQPSEK------------------ 137
Q PK +PKQ D D K S+ E+ S+
Sbjct: 210 PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269
Query: 138 --------STEPKTKPQDMISAGGESVAGITAISGKPGDKKK------------EKKSLT 177
++ P+TK D++ GESV KP ++ EK
Sbjct: 270 AKLPLQRDASRPQTKQADIVR--GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPG 327
Query: 178 PAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSST-----Y 232
PA P P +PSG + A + P T + GP P T
Sbjct: 328 PAKP----PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGP-AKPPAQQTGSEKPS 382
Query: 233 IEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAA--- 289
E+ G + + PP + A++ G PP P L S PT
Sbjct: 383 SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442
Query: 290 ----GKKTEKEESTEVLKAQSAGTVRS-------AAPPQEKKRKVEKDTMSDQALEALSA 338
GK ++ AQ G + A PP ++ + + + S
Sbjct: 443 QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 339 SLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEP 398
G+ + P+ + + + + ++ G + KP+ + KP+
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562
Query: 399 EEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVC---RTS 453
KP P S+ ++ C P T E P + C +T+
Sbjct: 563 SGKPLQPPTVSPSAKQPPSQGLPKTIC------PLCNTTELLLHVPEKANFNTCTECQTT 616
Query: 454 MCSIQSAPPEP------------ATLKGTVPDD--------------AVEALADSLGKKE 487
+CS+ P P +K + D A ++ K
Sbjct: 617 VCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSS 676
Query: 488 ADPEDGKPVMDKVKEKAKEEDREKLGEKEETIP----------PDYRLEEVKDKDG--KP 535
P+ P K+ A ++D K E ++ P P + ++ + D KP
Sbjct: 677 PQPQQTSPK----KDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP 732
Query: 536 LLPKE----SKEQLPPMSEDF-----LLDALSEDFSGPQNASSLKFEDAKLAAAISEVVS 586
PKE S++ P+++D ++ ++ S + +K+ + E
Sbjct: 733 APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE--K 790
Query: 587 QTPASTTQAGAP------------PRDTSQ-----SDKDLDDALDKLSDSLGQRQPDPDE 629
TP T + P P D+ SD + S+S GQ+Q DP +
Sbjct: 791 TTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQ 850
Query: 630 NKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADD 689
K K + K + K + PP R GQ P + S KP +
Sbjct: 851 KKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPR---PTAGQTVPT------PQQSPKPQEQ 901
Query: 690 QDPIDALSGDLDSCP-STTETSQNTAKDK 717
G + P S T Q T K
Sbjct: 902 SRRFSLNLGSITDAPKSQPTTPQETVTGK 930
>gi|42518068 trans-golgi network protein 2 [Homo sapiens]
Length = 437
Score = 62.4 bits (150), Expect = 1e-09
Identities = 77/346 (22%), Positives = 135/346 (39%), Gaps = 28/346 (8%)
Query: 15 RRAAAARRTHEHVSEK---TSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKV 71
R +A TH +S++ +++S +P K S K +A + + + +G A K
Sbjct: 34 RPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKD 93
Query: 72 SASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAE 131
S++ + T + + K S S L TG + A +++ E
Sbjct: 94 SSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAE-----AQTPE 148
Query: 132 QQPSEKSTEPKTKPQDMISAGGE--------SVAGITAISGKPGDKKKEKKSLTPA-VPV 182
P+ E KT+ +G E + +G + K G K + TP VP
Sbjct: 149 DSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPN 208
Query: 183 ESKPDKPSGKSGMDAALDDLIDTLGGPEET-EEENTTYTGPEVSDPMSSTYIEELGKREV 241
+S +K + K G + + + + GP ++ EE T+ P P + + + +
Sbjct: 209 KSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDH--SKPI 266
Query: 242 TIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT--CGSPTAAGKKTEKEEST 299
+ P +EL + T AD K + P A S + T P K +E E
Sbjct: 267 SNPSDNKEL---PKADTNQLADKGK-LSP-HAFKTESGEETDLISPPQEEVKSSEPTEDV 321
Query: 300 EVLKAQSAGT-VRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQ 344
E +A+ T +PP+E+K K+ S+ LS S G+ +
Sbjct: 322 EPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEK 367
Score = 52.0 bits (123), Expect = 2e-06
Identities = 76/334 (22%), Positives = 132/334 (39%), Gaps = 55/334 (16%)
Query: 71 VSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSA 130
V S+G S S++ + K+ PE ++ PK P ++S A +++
Sbjct: 33 VRPSAGNVSTHPSLSQRPGGSTKSHPEPQT----PKDSPSKSS-----------AEAQTP 77
Query: 131 EQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPS 190
E P++ E KT+ +G E+ + S + + K S + + P P +
Sbjct: 78 EDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDST 137
Query: 191 GKSGMDAAL-DDLIDTLGGPEETEEENTTYTGPEV-----------------SDPMSSTY 232
GKSG +A +D + G +T++++ + +G E D S +
Sbjct: 138 GKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSG 197
Query: 233 IEELGKREVTIPPKY-RELLAKKEGITGPPADSSKPI-GPDDAIDALSSDFTCGSPTAAG 290
E+ ++V P K E K+G A+ PI GP S + A
Sbjct: 198 AEDQTPKDV--PNKSGAEKQTPKDGSNKSGAEEQGPIDGP--------------SKSGAE 241
Query: 291 KKTEKEESTEVLKAQSAGTVRS--AAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPE 348
++T K+ +V+ Q + S + P + K + DT LS ++ E
Sbjct: 242 EQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEE 301
Query: 349 LDLRS--IKEVDEAKAKEEKLEKCGEDDETIPSE 380
DL S +EV ++ E+ K EDD+T P E
Sbjct: 302 TDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEE 335
Score = 33.9 bits (76), Expect = 0.57
Identities = 33/160 (20%), Positives = 55/160 (34%), Gaps = 18/160 (11%)
Query: 591 STTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR--QPDPDENKPMEDKVKEKAKAEHRDK 648
ST+++G+ + T S L DS G+ + E+ P + K + + K
Sbjct: 108 STSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSK 167
Query: 649 LGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTE 708
G T K V P K D + P D A P+ +
Sbjct: 168 SGSEAQTT--------------KDV--PNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSG 211
Query: 709 TSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPK 748
+ T KD K+ + + P +G + + T + S K
Sbjct: 212 AEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNK 251
Score = 33.1 bits (74), Expect = 0.97
Identities = 41/189 (21%), Positives = 70/189 (37%), Gaps = 23/189 (12%)
Query: 563 GPQNASSLKFEDAKLAAAISEVVSQTPASTT-----QAGAPPRDTSQSDKDLDDALDKLS 617
G + S + + K + + S QTP +T +A P ++S + D S
Sbjct: 107 GSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPS 166
Query: 618 DSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPT 677
S + Q D P + + + K G D T + + + +G +K T
Sbjct: 167 KSGSEAQTTKDV--PNKSGADGQTPKDGSSKSGAEDQTP----KDVPNKSGAEKQ----T 216
Query: 678 KKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDS 737
K +K A++Q PID PS + + T+KD K + K+ K +
Sbjct: 217 PKDGSNKSGAEEQGPIDG--------PSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISN 268
Query: 738 AKTTEETSK 746
+E K
Sbjct: 269 PSDNKELPK 277
Score = 31.6 bits (70), Expect = 2.8
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 9/73 (12%)
Query: 674 KPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNG-G 732
+P T K SK A+ Q P D P+ + T KD K+ + +K K
Sbjct: 59 EPQTPKDSPSKSSAEAQTPEDT--------PNKSGAEAKTQKDSSNKSGAEAKTQKGSTS 110
Query: 733 KAKDSAKTTEETS 745
K+ A+TT++++
Sbjct: 111 KSGSEAQTTKDST 123
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 62.0 bits (149), Expect = 2e-09
Identities = 130/610 (21%), Positives = 215/610 (35%), Gaps = 137/610 (22%)
Query: 63 GGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQ------STKPKSLPKQASDTG 116
G A K ASS + SS E + V+ P KK+ P +AS++
Sbjct: 72 GPVAKKAKKKASSSDSEDSSE----EEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESS 127
Query: 117 SNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSL 176
S++ + ++QP +K +P+ K +S + S + K +K +
Sbjct: 128 SSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKI 187
Query: 177 TPA-VPVESK-PDKPSGKS-----GMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMS 229
TP V ++K P KP+ + G A+ + +++EEE T +
Sbjct: 188 TPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKK------ 241
Query: 230 STYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAA 289
T+P K +++AK P ++ P + + SSD
Sbjct: 242 ------------TVPKK--QVVAK-----APVKAATTPTRKSSSSEDSSSD--------- 273
Query: 290 GKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPEL 349
E+EE + +K G S PP K SLGT+ +
Sbjct: 274 ----EEEEQKKPMK-NKPGPYSSVPPPSAPPPK---------------KSLGTQPPK--- 310
Query: 350 DLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESE 409
K V++ + E + E D + SE KP T K ++ + KP P ++
Sbjct: 311 -----KAVEKQQPVESSEDSSDESDSS--SEEEKKPPT----KAVVSKATTKPPPAKKAA 359
Query: 410 LIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKG 469
S D D SE E PSKP T+ S + PA +++ PA
Sbjct: 360 ESSSDSSDSDSSEDDEAPSKPAGTTKNS-SNKPAVTTKS---------------PAVKPA 403
Query: 470 TVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVK 529
P V G+ ++ + + + E+ E+E+T + K
Sbjct: 404 AAPKQPVGG--------------GQKLLTRKADSSSSEEESSSSEEEKT---KKMVATTK 446
Query: 530 DKDGKPLLPKESKEQLPPMSEDFLLD---ALSEDFSGPQNASSLKFEDAKLAAAISEVVS 586
K +Q P S D D + SE+ + S++K + K+A
Sbjct: 447 PKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGG---AAP 503
Query: 587 QTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDEN-------------KPM 633
PAS + A ++S SD ++ +KL R P N K
Sbjct: 504 SKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNS 563
Query: 634 EDKVKEKAKA 643
E++ +EK KA
Sbjct: 564 EEEEEEKKKA 573
Score = 58.9 bits (141), Expect = 2e-08
Identities = 120/526 (22%), Positives = 198/526 (37%), Gaps = 71/526 (13%)
Query: 4 PGQKPAASPR-----PRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSS 58
P K AA P P AAA+ + SE++S+ + +KK +K
Sbjct: 100 PPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGV--------- 150
Query: 59 RTYAGGTASATKVSASSGATSKSSSMN--PTETKAVKTEPEKKSQSTKP----KSLPKQA 112
+ A + K + SS + S SSS + P K T K+Q+ P ++ PK A
Sbjct: 151 KPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIA 210
Query: 113 SDTGSNDAHNKKAVSRSAEQQPSEKSTEP-KTKPQDMISAGGESVAGIT------AISGK 165
+ ++ + + + S S + + + + P KT P+ + A A T +
Sbjct: 211 NGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDS 270
Query: 166 PGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVS 225
D+++E+K P+++KP S A P++ E+ E S
Sbjct: 271 SSDEEEEQKK-----PMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDS 325
Query: 226 DPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGS 285
S + EE K P + +++K T PP D+ D+ SS+
Sbjct: 326 SDESDSSSEEEKK------PPTKAVVSK--ATTKPPPAKKAAESSSDSSDSDSSEDDEAP 377
Query: 286 PTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQA 345
AG T K S + + V+ AA P++ +K L TR+A
Sbjct: 378 SKPAG--TTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQK--------------LLTRKA 421
Query: 346 EPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPR 405
+ S E + + ++EEK +K T + K A K P+
Sbjct: 422 D-----SSSSEEESSSSEEEKTKKM---VATTKPKATAKAALSLPAKQ-APQGSRDSSSD 472
Query: 406 SESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPA 465
S+S +E E +S K+KP K SK A+ A +A S S S+ E
Sbjct: 473 SDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPAS-AKKGKAESSNSSSSDDSSEEEEE 531
Query: 466 TLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREK 511
LKG A+ G ++GK + +E EE+++K
Sbjct: 532 KLKGKGSPRPQAPKAN--GTSALTAQNGKAAKNSEEE---EEEKKK 572
Score = 57.0 bits (136), Expect = 6e-08
Identities = 96/467 (20%), Positives = 162/467 (34%), Gaps = 90/467 (19%)
Query: 10 ASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTY----AGGT 65
A P+P RAA + S +S S S + S+E+KAA+ + A
Sbjct: 198 APPKPARAAPKIANGKAASSSSSSSSSSSSDD--SEEEKAAATPKKTVPKKQVVAKAPVK 255
Query: 66 ASATKVSASSGATSKSSSMNPTETKAVKTEP-------------EKKSQSTKP--KSLPK 110
A+ T SS + SS + K +K +P KKS T+P K++ K
Sbjct: 256 AATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEK 315
Query: 111 QASDTGSNDAHNKKAVSRSAEQQPSEKSTEPK--TKP-------------QDMISAGGES 155
Q S D+ ++ S E++P K+ K TKP D S+ +
Sbjct: 316 QQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDE 375
Query: 156 VAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEE 215
A + K K + +PAV + P +P G L+ +EEE
Sbjct: 376 APSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGG------QKLLTRKADSSSSEEE 429
Query: 216 NTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAID 275
+++ + +++T + K +++P K P G D+
Sbjct: 430 SSSSEEEKTKKMVATTKPKATAKAALSLPAK------------------QAPQGSRDS-- 469
Query: 276 ALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEA 335
SSD S +KT K + + + AG + P KK K E S
Sbjct: 470 --SSDSDSSSSEEEEEKTSKS-AVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSD--- 523
Query: 336 LSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLL 395
D ++ +EEKL+ G P T ++GK
Sbjct: 524 ----------------------DSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAK 561
Query: 396 PEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 442
EE+ + + + ++ + R + + T + ++ K P
Sbjct: 562 NSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTP 608
Score = 55.8 bits (133), Expect = 1e-07
Identities = 84/379 (22%), Positives = 139/379 (36%), Gaps = 67/379 (17%)
Query: 420 RSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEAL 479
+++ K S + +EE + P +A + PP A K + + E+
Sbjct: 77 KAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGL---PPGKAAAKASESSSSEESS 133
Query: 480 ADSLGKKEADPEDGK--PVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 537
D D ED K PV VK +AK K D E+ K+ KP +
Sbjct: 134 DDD------DEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKI 187
Query: 538 -----------PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVS 586
P + P ++ A S S ++SS E+ K AA + V
Sbjct: 188 TPVTVKAQTKAPPKPARAAPKIANG---KAASSSSSSSSSSSSDDSEEEKAAATPKKTVP 244
Query: 587 Q----TPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQ-----------PDPDEN- 630
+ A A P R +S S+ D ++ + + P P ++
Sbjct: 245 KKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSL 304
Query: 631 --KPMEDKVKEKAKAEHRDKLGERDDTIPPEYRH----LLDDNGQDKPVKPPTKKSEDSK 684
+P + V+++ E + + D+ E + + KP PP KK+ +S
Sbjct: 305 GTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKP--PPAKKAAESS 362
Query: 685 KPADDQDPIDALSGDLDSCPS----TTETSQN----TAKDKCKKAASSSKAPKNGG---- 732
+ D D S + D PS TT+ S N T K K A++ K P GG
Sbjct: 363 SDSSDSD-----SSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLL 417
Query: 733 -KAKDSAKTTEETSKPKDD 750
+ DS+ + EE+S +++
Sbjct: 418 TRKADSSSSEEESSSSEEE 436
Score = 53.1 bits (126), Expect = 9e-07
Identities = 115/525 (21%), Positives = 187/525 (35%), Gaps = 54/525 (10%)
Query: 3 QPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYA 62
Q G KP A A+ + + + P K + K + A + A
Sbjct: 147 QKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAA 206
Query: 63 GGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHN 122
A+ S+SS ++S SSS + E KA T + + P +A+ T +
Sbjct: 207 PKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRK--- 263
Query: 123 KKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPG-DKKKEKKSLTPAVP 181
S S+E S++ E K KP SV +A K + KK++ P
Sbjct: 264 ----SSSSEDSSSDEEEEQK-KPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQP 318
Query: 182 VESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREV 241
VES D D D+ E+ + P + E
Sbjct: 319 VESSEDS-----------SDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSD 367
Query: 242 TIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKK-TEKEESTE 300
+ + E +K G T S+KP A+++ P AA K+ +
Sbjct: 368 SDSSEDDEAPSKPAGTT--KNSSNKP--------AVTTKSPAVKPAAAPKQPVGGGQKLL 417
Query: 301 VLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEA 360
KA S+ + ++ +E+K K T +A + SL +QA P+ S + D +
Sbjct: 418 TRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQA-PQGSRDSSSDSDSS 476
Query: 361 KAKEEKLEKCGEDDETIPSEYRLKPATDKDG-KPLLPEPEEKPKPRSESELIDELSEDFD 419
++E E+++T S + KP G P P +K K S + S+D
Sbjct: 477 SSEE-------EEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSN---SSSSDDSS 526
Query: 420 RSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEAL 479
E ++ K + + + KA S + + S E K V V +
Sbjct: 527 EEEEEKLKGKGSPRPQAPKANG---TSALTAQNGKAAKNSEEEEEEKKKAAV----VVSK 579
Query: 480 ADSLGKK---EADPEDGKPVMDKVK-EKAKEEDREKLGEKEETIP 520
+ SL K+ EA E P K+K + + K GEK + P
Sbjct: 580 SGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSP 624
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 61.6 bits (148), Expect = 3e-09
Identities = 145/757 (19%), Positives = 276/757 (36%), Gaps = 86/757 (11%)
Query: 26 HVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMN 85
H + KT K ++K S S T G +A ++ +S T SS
Sbjct: 720 HTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNY 779
Query: 86 PTET-KAVKTEPEKKSQSTKPKSLPKQAS-DTGSNDAHNKKAVSR------SAEQQPSEK 137
+E K +K+ + + T K +P D+ ++ H+KK + Q+ S
Sbjct: 780 DSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSD 839
Query: 138 STEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDA 197
E K + + SA G T + + KK++ S + DK SGK
Sbjct: 840 DAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASAS-----TDGVDKLSGKEQSFT 894
Query: 198 ALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGI 257
+L+ + + +E + T T +V D +S E+ K++ + + K+G
Sbjct: 895 SLE--VRKVAETKEKSKHLKTKTCKKVQDGLSD-IAEKFLKKDQSDETSEDDKKQSKKGT 951
Query: 258 --TGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAP 315
P+D K + + SSD T K E+EE K +++
Sbjct: 952 EEKKKPSDFKKKVIKMEQQYESSSDGT-------EKLPEREEICHFPK--GIKQIKNGTT 1002
Query: 316 PQEKKRK-------VEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAK----- 363
EKK K +KD +SD A ++ +E + ++ + K
Sbjct: 1003 DGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKS 1062
Query: 364 EEKLEKCGEDDETIPSEYRLKP----ATDKDGKPLLPEPEEKPKPRSESELIDELSEDFD 419
K + C D +Y +K ++DK K + + ++ I S D
Sbjct: 1063 SRKRQDCSSSD---TEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSD 1119
Query: 420 RSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEAL 479
E E K ++T K A + + R S+ + S + A + + D +
Sbjct: 1120 AEESSEDNKKKKQRTSSKKKAV---IVKEKKRNSLRT--STKRKQADITSSSSSDIEDDD 1174
Query: 480 ADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPK 539
+S+G+ +D + KPV + + + + G++ + +++ D D P
Sbjct: 1175 QNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD-DDDDNDP---- 1229
Query: 540 ESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPP 599
E++ +++ LL+ + + S ++ SS D + Q + A
Sbjct: 1230 ENR-----IAKKMLLEEIKANLSSDEDGSS----DDEPEEGKKRTGKQNEENPGDEEAKN 1280
Query: 600 RDTSQSDKDLDDALDK------LSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERD 653
+ S+SD D +++ L L + E K + K ++ K +R K+ D
Sbjct: 1281 QVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSED 1340
Query: 654 DTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNT 713
D + Q+ V +SED ++P A +L+ + Q
Sbjct: 1341 SE---------DSDFQESGVSEEVSESEDEQRPRTR----SAKKAELEE--NQRSYKQKK 1385
Query: 714 AKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 750
+ + K SS K+ + ++ K EE + +++
Sbjct: 1386 KRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEE 1422
Score = 50.8 bits (120), Expect = 4e-06
Identities = 149/765 (19%), Positives = 283/765 (36%), Gaps = 106/765 (13%)
Query: 21 RRTHEH-VSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATS 79
+ T EH V + E+ ++ GEK + EKK S ++ SR V T+
Sbjct: 389 KNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTN 448
Query: 80 KSSSMNPTETKAVKTEPEKKSQSTKPK------SLPKQASDTGSNDAHNKKAVSRSAEQQ 133
KS+ ++ K EP+ + +T S+P + + V S + Q
Sbjct: 449 KSTGGEHKKSDR-KEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQ 507
Query: 134 PSEKS-TEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGK 192
S TE + + + I++ + G K K +T + V+ P S
Sbjct: 508 GDGSSGTEQEVESSSV-------KLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNS 560
Query: 193 SGMDAALDDLIDTLGGPEETEEENTTYTGPEVSD---PMSSTYIEELGKREVTIPPKYRE 249
A ++ P++ + + P++ ++ E L + EV+
Sbjct: 561 PIKGADCQEV------PQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVS------- 607
Query: 250 LLAKKEGITGPPADSSKPIGPDDAIDAL--SSDFTCGSPTAAGKKTEKEESTEVLKAQSA 307
LL ++ + P + P+ + + +SD C EK++ + ++ +
Sbjct: 608 LLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETV-----KEKQKLSVPVRKKDK 662
Query: 308 GTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKL 367
+A K K+ K S+ + + E L+ + + + + + +
Sbjct: 663 RNSSDSAIDNPKPNKLPKSKQSE------TVDQNSDSDEMLAILKEVSRMSHSSSSDTDI 716
Query: 368 EKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKP 427
+ + +T+ Y LK KD K K K +S + DFD + K
Sbjct: 717 NEIHTNHKTL---YDLKTQAGKDDK-------GKRKRKSSTS-----GSDFDTKKGKSAK 761
Query: 428 ----SKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSL 483
SK +T+ + + + + + SM I +A + T D+ E +
Sbjct: 762 SSIISKKKRQTQSESSNYDSELEKEI--KSMSKIGAARTTKKRIPNTKDFDSSE--DEKH 817
Query: 484 GKKEADPEDGKPVMDKVK----EKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPK 539
KK D + K + + + ++++RE E T+ D + E++D+ LPK
Sbjct: 818 SKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDR-----LPK 872
Query: 540 ESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPP 599
K+Q ++ +D LS Q+ +SL+ S+ + Q G
Sbjct: 873 --KQQASASTDG--VDKLS---GKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGL-- 923
Query: 600 RDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHR--------DKLGE 651
D ++ D + + D Q + +E K D K+ K E + +KL E
Sbjct: 924 SDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPE 983
Query: 652 RDDTIP-PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTE-T 709
R++ P+ + + D K + + SKK + D + +G DSC S+ +
Sbjct: 984 REEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKK 1043
Query: 710 SQNTA----KDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 750
S+N A K +CK SS+ K +D + + E K+D
Sbjct: 1044 SKNGAYGREKKRCKLLGKSSR------KRQDCSSSDTEKYSMKED 1082
Score = 43.1 bits (100), Expect = 0.001
Identities = 124/647 (19%), Positives = 223/647 (34%), Gaps = 82/647 (12%)
Query: 15 RRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSAS 74
R+ A + +H+ KT + + G + L QS T S S
Sbjct: 899 RKVAETKEKSKHLKTKTCKKV-----QDGLSDIAEKFLKKDQSDET------SEDDKKQS 947
Query: 75 SGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQP 134
T + + + K +K E + +S S + LP++ + + ++
Sbjct: 948 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK 1007
Query: 135 SEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSG 194
S+K + +K +D +S E G G D ++KKS A E K K GKS
Sbjct: 1008 SKKIRDKTSKKKDELSDYAEKSTG----KGDSCDSSEDKKSKNGAYGREKKRCKLLGKSS 1063
Query: 195 MDAALDDLIDT----------------LGGPEETEEENTTY--TGPEVSDPMSSTYIEEL 236
DT L E E N + E+ SS+ EE
Sbjct: 1064 RKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEES 1123
Query: 237 G-----KREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGK 291
K++ T K ++ +K+ + + K D + SSD + G+
Sbjct: 1124 SEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQA---DITSSSSSDIEDDDQNSIGE 1180
Query: 292 KTEKEESTE------VLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQA 345
+ E+ + VL + + S K V D D +
Sbjct: 1181 GSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLE 1240
Query: 346 EPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPR 405
E + +L S ++ EE ++ G+ +E P + K + + + EE KPR
Sbjct: 1241 EIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDS---DSEESKKPR 1297
Query: 406 SESELIDELSEDFDRSECKEKPSKPTEKTE--------------ESKAAAPAPVSEAVCR 451
L+ D +EK +KP E E E + VSE V
Sbjct: 1298 YRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSE 1357
Query: 452 TSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREK 511
S P + K ++ + ++ ++ +K + +EE++E+
Sbjct: 1358 ----SEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEE 1413
Query: 512 LGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLL-----DALSEDFSGPQN 566
E+EE EE +D++ P + ++++ + +D L +AL E+ +
Sbjct: 1414 EEEEEEE-----EEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKR 1468
Query: 567 ASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDAL 613
+ + E KL EV+ AS T+ + D++ + L
Sbjct: 1469 IAEREREREKL----REVIEIEDASPTKCPITTKLVLDEDEETKEPL 1511
Score = 43.1 bits (100), Expect = 0.001
Identities = 86/426 (20%), Positives = 161/426 (37%), Gaps = 49/426 (11%)
Query: 11 SPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATK 70
S R R+ ++ T ++ S K S K + ++ +L S ++++ G++S+
Sbjct: 1062 SSRKRQDCSSSDTEKY-SMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSD- 1119
Query: 71 VSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSA 130
SS K ++ KAV + EKK S + + KQA T S+ + + S
Sbjct: 1120 AEESSEDNKKKKQRTSSKKKAVIVK-EKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSI 1178
Query: 131 EQQPSEKSTEPKTKP--QDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDK 188
+ S+ E K KP ++++ ++ T GD+ +L+ +VPV D
Sbjct: 1179 GEGSSD---EQKIKPVTENLV------LSSHTGFCQSSGDE-----ALSKSVPVTVDDDD 1224
Query: 189 PSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYR 248
A L++ + ++E+ ++ PE + EE E
Sbjct: 1225 DDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEE------- 1277
Query: 249 ELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAG 308
AK + + +DS + P L T + +K K + + +K ++
Sbjct: 1278 ---AKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRN-- 1332
Query: 309 TVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLE 368
+RKV + D + S ++E E R+ AK+ +LE
Sbjct: 1333 -----------RRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRT------RSAKKAELE 1375
Query: 369 KCGEDDETIPSEYRLKPATDKDGKPLL-PEPEEKPKPRSESELIDELSEDFDRSECKEKP 427
+ + R+K D + E EE+ K E E +E E+ D ++ + P
Sbjct: 1376 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1435
Query: 428 SKPTEK 433
K +K
Sbjct: 1436 GKGRKK 1441
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 61.6 bits (148), Expect = 3e-09
Identities = 145/757 (19%), Positives = 276/757 (36%), Gaps = 86/757 (11%)
Query: 26 HVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMN 85
H + KT K ++K S S T G +A ++ +S T SS
Sbjct: 758 HTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNY 817
Query: 86 PTET-KAVKTEPEKKSQSTKPKSLPKQAS-DTGSNDAHNKKAVSR------SAEQQPSEK 137
+E K +K+ + + T K +P D+ ++ H+KK + Q+ S
Sbjct: 818 DSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSD 877
Query: 138 STEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDA 197
E K + + SA G T + + KK++ S + DK SGK
Sbjct: 878 DAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASAS-----TDGVDKLSGKEQSFT 932
Query: 198 ALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGI 257
+L+ + + +E + T T +V D +S E+ K++ + + K+G
Sbjct: 933 SLE--VRKVAETKEKSKHLKTKTCKKVQDGLSD-IAEKFLKKDQSDETSEDDKKQSKKGT 989
Query: 258 --TGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAP 315
P+D K + + SSD T K E+EE K +++
Sbjct: 990 EEKKKPSDFKKKVIKMEQQYESSSDGT-------EKLPEREEICHFPK--GIKQIKNGTT 1040
Query: 316 PQEKKRK-------VEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAK----- 363
EKK K +KD +SD A ++ +E + ++ + K
Sbjct: 1041 DGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKS 1100
Query: 364 EEKLEKCGEDDETIPSEYRLKP----ATDKDGKPLLPEPEEKPKPRSESELIDELSEDFD 419
K + C D +Y +K ++DK K + + ++ I S D
Sbjct: 1101 SRKRQDCSSSD---TEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSD 1157
Query: 420 RSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEAL 479
E E K ++T K A + + R S+ + S + A + + D +
Sbjct: 1158 AEESSEDNKKKKQRTSSKKKAV---IVKEKKRNSLRT--STKRKQADITSSSSSDIEDDD 1212
Query: 480 ADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPK 539
+S+G+ +D + KPV + + + + G++ + +++ D D P
Sbjct: 1213 QNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD-DDDDNDP---- 1267
Query: 540 ESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPP 599
E++ +++ LL+ + + S ++ SS D + Q + A
Sbjct: 1268 ENR-----IAKKMLLEEIKANLSSDEDGSS----DDEPEEGKKRTGKQNEENPGDEEAKN 1318
Query: 600 RDTSQSDKDLDDALDK------LSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERD 653
+ S+SD D +++ L L + E K + K ++ K +R K+ D
Sbjct: 1319 QVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSED 1378
Query: 654 DTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNT 713
D + Q+ V +SED ++P A +L+ + Q
Sbjct: 1379 SE---------DSDFQESGVSEEVSESEDEQRPRTR----SAKKAELEE--NQRSYKQKK 1423
Query: 714 AKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 750
+ + K SS K+ + ++ K EE + +++
Sbjct: 1424 KRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEE 1460
Score = 50.8 bits (120), Expect = 4e-06
Identities = 149/765 (19%), Positives = 283/765 (36%), Gaps = 106/765 (13%)
Query: 21 RRTHEH-VSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATS 79
+ T EH V + E+ ++ GEK + EKK S ++ SR V T+
Sbjct: 427 KNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTN 486
Query: 80 KSSSMNPTETKAVKTEPEKKSQSTKPK------SLPKQASDTGSNDAHNKKAVSRSAEQQ 133
KS+ ++ K EP+ + +T S+P + + V S + Q
Sbjct: 487 KSTGGEHKKSDR-KEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQ 545
Query: 134 PSEKS-TEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGK 192
S TE + + + I++ + G K K +T + V+ P S
Sbjct: 546 GDGSSGTEQEVESSSV-------KLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNS 598
Query: 193 SGMDAALDDLIDTLGGPEETEEENTTYTGPEVSD---PMSSTYIEELGKREVTIPPKYRE 249
A ++ P++ + + P++ ++ E L + EV+
Sbjct: 599 PIKGADCQEV------PQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVS------- 645
Query: 250 LLAKKEGITGPPADSSKPIGPDDAIDAL--SSDFTCGSPTAAGKKTEKEESTEVLKAQSA 307
LL ++ + P + P+ + + +SD C EK++ + ++ +
Sbjct: 646 LLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETV-----KEKQKLSVPVRKKDK 700
Query: 308 GTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKL 367
+A K K+ K S+ + + E L+ + + + + + +
Sbjct: 701 RNSSDSAIDNPKPNKLPKSKQSE------TVDQNSDSDEMLAILKEVSRMSHSSSSDTDI 754
Query: 368 EKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKP 427
+ + +T+ Y LK KD K K K +S + DFD + K
Sbjct: 755 NEIHTNHKTL---YDLKTQAGKDDK-------GKRKRKSSTS-----GSDFDTKKGKSAK 799
Query: 428 ----SKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSL 483
SK +T+ + + + + + SM I +A + T D+ E +
Sbjct: 800 SSIISKKKRQTQSESSNYDSELEKEI--KSMSKIGAARTTKKRIPNTKDFDSSE--DEKH 855
Query: 484 GKKEADPEDGKPVMDKVK----EKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPK 539
KK D + K + + + ++++RE E T+ D + E++D+ LPK
Sbjct: 856 SKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDR-----LPK 910
Query: 540 ESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPP 599
K+Q ++ +D LS Q+ +SL+ S+ + Q G
Sbjct: 911 --KQQASASTDG--VDKLS---GKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGL-- 961
Query: 600 RDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHR--------DKLGE 651
D ++ D + + D Q + +E K D K+ K E + +KL E
Sbjct: 962 SDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPE 1021
Query: 652 RDDTIP-PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTE-T 709
R++ P+ + + D K + + SKK + D + +G DSC S+ +
Sbjct: 1022 REEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKK 1081
Query: 710 SQNTA----KDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 750
S+N A K +CK SS+ K +D + + E K+D
Sbjct: 1082 SKNGAYGREKKRCKLLGKSSR------KRQDCSSSDTEKYSMKED 1120
Score = 43.1 bits (100), Expect = 0.001
Identities = 124/647 (19%), Positives = 223/647 (34%), Gaps = 82/647 (12%)
Query: 15 RRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSAS 74
R+ A + +H+ KT + + G + L QS T S S
Sbjct: 937 RKVAETKEKSKHLKTKTCKKV-----QDGLSDIAEKFLKKDQSDET------SEDDKKQS 985
Query: 75 SGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQP 134
T + + + K +K E + +S S + LP++ + + ++
Sbjct: 986 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK 1045
Query: 135 SEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSG 194
S+K + +K +D +S E G G D ++KKS A E K K GKS
Sbjct: 1046 SKKIRDKTSKKKDELSDYAEKSTG----KGDSCDSSEDKKSKNGAYGREKKRCKLLGKSS 1101
Query: 195 MDAALDDLIDT----------------LGGPEETEEENTTY--TGPEVSDPMSSTYIEEL 236
DT L E E N + E+ SS+ EE
Sbjct: 1102 RKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEES 1161
Query: 237 G-----KREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGK 291
K++ T K ++ +K+ + + K D + SSD + G+
Sbjct: 1162 SEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQA---DITSSSSSDIEDDDQNSIGE 1218
Query: 292 KTEKEESTE------VLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQA 345
+ E+ + VL + + S K V D D +
Sbjct: 1219 GSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLE 1278
Query: 346 EPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPR 405
E + +L S ++ EE ++ G+ +E P + K + + + EE KPR
Sbjct: 1279 EIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDS---DSEESKKPR 1335
Query: 406 SESELIDELSEDFDRSECKEKPSKPTEKTE--------------ESKAAAPAPVSEAVCR 451
L+ D +EK +KP E E E + VSE V
Sbjct: 1336 YRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSE 1395
Query: 452 TSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREK 511
S P + K ++ + ++ ++ +K + +EE++E+
Sbjct: 1396 ----SEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEE 1451
Query: 512 LGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLL-----DALSEDFSGPQN 566
E+EE EE +D++ P + ++++ + +D L +AL E+ +
Sbjct: 1452 EEEEEEE-----EEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKR 1506
Query: 567 ASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDAL 613
+ + E KL EV+ AS T+ + D++ + L
Sbjct: 1507 IAEREREREKL----REVIEIEDASPTKCPITTKLVLDEDEETKEPL 1549
Score = 43.1 bits (100), Expect = 0.001
Identities = 86/426 (20%), Positives = 161/426 (37%), Gaps = 49/426 (11%)
Query: 11 SPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATK 70
S R R+ ++ T ++ S K S K + ++ +L S ++++ G++S+
Sbjct: 1100 SSRKRQDCSSSDTEKY-SMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSD- 1157
Query: 71 VSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSA 130
SS K ++ KAV + EKK S + + KQA T S+ + + S
Sbjct: 1158 AEESSEDNKKKKQRTSSKKKAVIVK-EKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSI 1216
Query: 131 EQQPSEKSTEPKTKP--QDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDK 188
+ S+ E K KP ++++ ++ T GD+ +L+ +VPV D
Sbjct: 1217 GEGSSD---EQKIKPVTENLV------LSSHTGFCQSSGDE-----ALSKSVPVTVDDDD 1262
Query: 189 PSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYR 248
A L++ + ++E+ ++ PE + EE E
Sbjct: 1263 DDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEE------- 1315
Query: 249 ELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAG 308
AK + + +DS + P L T + +K K + + +K ++
Sbjct: 1316 ---AKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRN-- 1370
Query: 309 TVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLE 368
+RKV + D + S ++E E R+ AK+ +LE
Sbjct: 1371 -----------RRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRT------RSAKKAELE 1413
Query: 369 KCGEDDETIPSEYRLKPATDKDGKPLL-PEPEEKPKPRSESELIDELSEDFDRSECKEKP 427
+ + R+K D + E EE+ K E E +E E+ D ++ + P
Sbjct: 1414 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1473
Query: 428 SKPTEK 433
K +K
Sbjct: 1474 GKGRKK 1479
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 61.2 bits (147), Expect = 3e-09
Identities = 123/591 (20%), Positives = 220/591 (37%), Gaps = 90/591 (15%)
Query: 69 TKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSR 128
+K G K S + +++ ++ + K ++ KPK SD +D NK
Sbjct: 93 SKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSD--DDDDFNKLPKKA 150
Query: 129 SAEQQPSEKSTE---------PKTKPQDMISAGGESV-AGITAISGKPGDKKKEKKSLTP 178
+ Q S K + K K + I++ GES + + G KK +K P
Sbjct: 151 KGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGP 210
Query: 179 AVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEE--- 235
+ ++ D S K I T+ + ++E E + +E
Sbjct: 211 NIESGNEDDDASFK----------IKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELE 260
Query: 236 LGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEK 295
GK++ + K +E K E T SK I A S+ +PTAA E
Sbjct: 261 TGKKDQS---KQKESQRKFEEETV----KSKVTVDTGVIPA--SEEKAETPTAAEDDNEG 311
Query: 296 EESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMS--DQALEALSASLGTRQAEPELDLRS 353
++ + K + +EKK+ K T+ +AL L ++ E E ++
Sbjct: 312 DKKKKDKKKKKG---EKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKR 368
Query: 354 IKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDE 413
++E++ + +EE+LE+ + + E K K+GK LL + + + + R+E+ L
Sbjct: 369 LEELEAKRKEEERLEQ-EKRERKKQKEKERKERLKKEGK-LLTKSQREARARAEATLKLL 426
Query: 414 LSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSM--CSIQSAPPEPATLKGTV 471
++ + P K ++ + P + SM C+
Sbjct: 427 QAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCA--------------- 471
Query: 472 PDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDK 531
AVE + + +KE P +P ++ E A +D E + EET + ++ K
Sbjct: 472 ---AVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVK 528
Query: 532 DGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPAS 591
+ P+E +E+ ED + E+ G S ED K++
Sbjct: 529 EN----PEEEEEEEEEEEEDEESEE-EEEEEGESEGSEGDEEDEKVS------------- 570
Query: 592 TTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 642
D S K LD K S + D D+++ E++ +KAK
Sbjct: 571 ---------DEKDSGKTLDKKPSKEMSS--DSEYDSDDDRTKEERAYDKAK 610
Score = 57.4 bits (137), Expect = 5e-08
Identities = 128/653 (19%), Positives = 239/653 (36%), Gaps = 120/653 (18%)
Query: 99 KSQSTKPKSLPKQASDTGSNDAHNKKA-VSRSAEQQPSEKSTEPKTKPQDM--------- 148
K Q K + K D + A + A ++ E Q S+ + + K QD
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKEL 62
Query: 149 --ISAGGESV-AGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDT 205
+S + + A ++ KP + +E+ + SK K G+ G + DD
Sbjct: 63 EELSLEAQGIKADRETVAVKPTENNEEEFT--------SKDKKKKGQKGKKQSFDD---- 110
Query: 206 LGGPEETEEENTTY---TGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPA 262
EE E++++ P+V S ++ K K ++ K +G +
Sbjct: 111 -NDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDG-SEEDE 168
Query: 263 DSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRK 322
D+SK I I++ +K +K+ K + + S + K
Sbjct: 169 DNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQ----KNKPGPNIESGNEDDDASFK 224
Query: 323 VEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYR 382
++ T++ + E R E + LR +KE +E + ++ K E E
Sbjct: 225 IK--TVAQKKAEKKERERKKRDEE-KAKLRKLKEKEELETGKKDQSKQKESQRKFEEETV 281
Query: 383 LKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 442
T G ++P EEK + + +E D+ D + + K+K + EK +E K
Sbjct: 282 KSKVTVDTG--VIPASEEKAETPTAAE--DDNEGDKKKKDKKKKKGEKEEKEKEKKKG-- 335
Query: 443 APVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKE 502
P AT+K +A+ L + +++ + E+ +++++
Sbjct: 336 -------------------PSKATVKAM--QEALAKLKEEEERQKREEEERIKRLEELEA 374
Query: 503 KAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKE---------------------- 540
K KEE+R + ++E + +E K+GK L +
Sbjct: 375 KRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVP 434
Query: 541 SKEQLP---PMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPAS--TTQA 595
SK+ LP P+ ED + + + + S++ L AA+ + P T
Sbjct: 435 SKDSLPKKRPIYEDKKRKKIPQQLESKEVSESME-----LCAAVEVMEQGVPEKEETPPP 489
Query: 596 GAPPRDTSQSDKDLDDALDKLSDSLGQR---------------QPDPDENKPMEDKVKEK 640
P + D LDD SD ++ + + +E + ED+ E+
Sbjct: 490 VEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEE 549
Query: 641 AKAEHRDKLG----ERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADD 689
+ E + G E D+ + E D+G+ KP + S DS+ +DD
Sbjct: 550 EEEEEGESEGSEGDEEDEKVSDE-----KDSGKTLDKKPSKEMSSDSEYDSDD 597
Score = 49.7 bits (117), Expect = 1e-05
Identities = 87/397 (21%), Positives = 150/397 (37%), Gaps = 50/397 (12%)
Query: 88 ETKAVKTEPEKKSQSTKPKSL----PKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 143
+ KA K E E+K + + L K+ +TG D +K R E++ + T
Sbjct: 230 QKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDT 289
Query: 144 KPQDMISAGGESVAGITAISG-KPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDA-ALDD 201
+I A E TA GDKKK+ K E + +K G S A+ +
Sbjct: 290 ---GVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQE 346
Query: 202 LIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRE------------ 249
+ L EE ++ + + + EE ++E K +E
Sbjct: 347 ALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGK 406
Query: 250 LLAKKEGITGPPADSSKPIGPDDAIDALSSD-FTCGSPTAAGKKTEK----------EES 298
LL K + A+++ + ++ S D P KK +K ES
Sbjct: 407 LLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSES 466
Query: 299 TEVLKA-----QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAE------- 346
E+ A Q PP E + + + + EA+++ T + E
Sbjct: 467 MELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIE 526
Query: 347 ----PELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKD-GKPLLPEPEEK 401
PE + +E +E + EE+ E+ GE + + E K + +KD GK L +P ++
Sbjct: 527 VKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKE 586
Query: 402 PKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESK 438
SE + D+ +++ +R+ K K + E SK
Sbjct: 587 MSSDSEYDSDDDRTKE-ERAYDKAKRRIEKRRLEHSK 622
Score = 42.0 bits (97), Expect = 0.002
Identities = 114/546 (20%), Positives = 198/546 (36%), Gaps = 139/546 (25%)
Query: 25 EHVSEKTSESPSKPGEK----KGSDEK-------KAASLGSSQSSRTYAGGTA---SATK 70
E + +K S+S K GSD+ K A + +S++ + G ++ K
Sbjct: 114 EELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKK 173
Query: 71 VSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSA 130
+ S S S + ++ + +KK+Q KP P S +DA K + A
Sbjct: 174 IKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPG--PNIESGNEDDDASFK--IKTVA 229
Query: 131 EQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPS 190
+++ +K E K + ++ K KEK+ L +SK +
Sbjct: 230 QKKAEKKERERKKRDEEKAKL----------------RKLKEKEELETGKKDQSKQKESQ 273
Query: 191 GKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYREL 250
K + EE K +VT+
Sbjct: 274 RK---------------------------------------FEEETVKSKVTV------- 287
Query: 251 LAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTV 310
G+ PA K P A D D KK EKEE
Sbjct: 288 ---DTGVI--PASEEKAETPTAAEDDNEGDKK--KKDKKKKKGEKEEK------------ 328
Query: 311 RSAAPPQEKKRKVEKDTMS--DQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLE 368
+EKK+ K T+ +AL L ++ E E ++ ++E++ + +EE+LE
Sbjct: 329 -----EKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLE 383
Query: 369 KCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESEL-------IDELSEDFDRS 421
+ + + E K K+GK LL + + + + R+E+ L ++ S+D S
Sbjct: 384 Q-EKRERKKQKEKERKERLKKEGK-LLTKSQREARARAEATLKLLQAQGVEVPSKD---S 438
Query: 422 ECKEKP---SKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPD----- 473
K++P K +K + + S +C Q P + T P+
Sbjct: 439 LPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDT 498
Query: 474 -----DAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEV 528
D EA+A +E + +G V +VKE +EE+ E+ E+E D EE
Sbjct: 499 EDAGLDDWEAMASD---EETEKVEGNKVHIEVKENPEEEEEEEEEEEE-----DEESEEE 550
Query: 529 KDKDGK 534
++++G+
Sbjct: 551 EEEEGE 556
Score = 39.3 bits (90), Expect = 0.014
Identities = 57/289 (19%), Positives = 115/289 (39%), Gaps = 24/289 (8%)
Query: 473 DDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEE----DREKLGEK-EETIPPDYRLEE 527
DD ++ L + + + D + V K E +EE D++K G+K ++ D EE
Sbjct: 56 DDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEE 115
Query: 528 VKDKDGKPLLPKESK-EQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVS 586
++DKD K + K E +D + L + G S+ K++ ++ S+ +
Sbjct: 116 LEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIK 175
Query: 587 QTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQP-----DPDENKPMEDKVKEKA 641
+ ++ + +SD+ L + + + P + D++ + K +
Sbjct: 176 E----RSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQK 231
Query: 642 KAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPAD---------DQDP 692
KAE +++ ++ D + R L + + K +K+ E +K + D
Sbjct: 232 KAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGV 291
Query: 693 IDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTT 741
I A ++ + + ++ K K KK K K K K +K T
Sbjct: 292 IPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKAT 340
Score = 37.0 bits (84), Expect = 0.067
Identities = 40/168 (23%), Positives = 77/168 (45%), Gaps = 26/168 (15%)
Query: 601 DTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEY 660
D+++ D DLD ++ + ++ +P ++K + K K+K + D L E ++ + E
Sbjct: 11 DSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEE-LSLEA 69
Query: 661 RHL-----------LDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTET 709
+ + ++N ++ K KK + KK + D + + L D DS
Sbjct: 70 QGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELE-DKDS------K 122
Query: 710 SQNTAKDKCKKAASS------SKAPKNG-GKAKDSAKTTEETSKPKDD 750
S+ TAK K + + S +K PK GKA+ S K + + + +D+
Sbjct: 123 SKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDN 170
>gi|109637791 transcription factor-like nuclear regulator [Homo
sapiens]
Length = 2624
Score = 61.2 bits (147), Expect = 3e-09
Identities = 140/694 (20%), Positives = 266/694 (38%), Gaps = 129/694 (18%)
Query: 25 EHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATS----- 79
E V ++T S ++ + +S S+ ++ G + +V+ + G+
Sbjct: 534 EKVEKRTDPILSLSNQQDATSVATESSESSTSDLPSFEVGIRALCEVNNAEGSCIEERNV 593
Query: 80 --KSSSMNPTETKAVKTEPEKKSQSTKP-------KSLPKQA-SDTGSNDAHNKKAVSRS 129
K++S+ +T+ VK + Q KP KS+ Q +++ S ++H+K +V ++
Sbjct: 594 DLKNNSLEIDQTENVKPMLRGRFQRPKPNLSRAGKKSVLSQGKTESESKNSHSKTSVEKN 653
Query: 130 AEQQPSE--------KSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVP 181
++ ++TE + + +S GE + + K+L P V
Sbjct: 654 HVEKDKMNTLDILRMETTERENPEAETVSVLGEKNCL---------QEGSQLKALRP-VQ 703
Query: 182 VESKPDKPSGKSGMDAALDDLI---DTLGG---------------PEETE-------EEN 216
V + KP +G A +++ + +G P+ E EE
Sbjct: 704 VRGRLQKPKPNAGKAAERKEILISQEEIGANVEKNENESCADRDTPQHMEDQSRKDFEEE 763
Query: 217 TTYTGPEVSDPMSSTYIEE-------LGKREVTIPPKYRELLAKKEGITGPPADSSKPIG 269
PE +D + +E L +E K ++ + P + + G
Sbjct: 764 DVILQPEKNDSFQNVQPDEPKVLNECLSVQENNKANKLNQVPILRTRFQKPKPNIGRGTG 823
Query: 270 PDDAI---DALSSDFTCGSPTAAGKKTEK-----------EESTEVLKAQSAGTVRSAAP 315
+ + L G AA ++T + E +T+ +++ T R A
Sbjct: 824 RREISSKEEVLEKILVSGEMAAALRETVRLDTSPKEMVPAEINTKEMQSDLKETGRRAIS 883
Query: 316 PQEKKRKVEKDTMS-DQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDD 374
P+EK V DT+ + L+A+ + R+ PE+ +D + ++ LE+ G
Sbjct: 884 PREKILDVIDDTIEMETGLKAMGREICLREKTPEV-------IDATEEIDKDLEEAG--- 933
Query: 375 ETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKT 434
R + + K+G PEE KP E E +L + S +EK + T+ T
Sbjct: 934 -------RREISPQKNG------PEEV-KPLGEVET--DLKATGNESSPREKTPEVTDAT 977
Query: 435 EESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGK 494
EE + + + T I P +K P D +E ++ G++ + E
Sbjct: 978 EE--------IDKNLEETGRRKISPRENGPEEVK---PVDEMETDLNATGRESSPREKTP 1026
Query: 495 PVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDK-DGKPLLPKESKEQLPPMSEDFL 553
V+D +E EE + E P + LEEVK + + L ++ P +
Sbjct: 1027 EVIDATEEIDLEET------EREVSPQENGLEEVKPLGEMETDLKATGRDSFPRGKTPEV 1080
Query: 554 LDALSE---DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLD 610
+DA+ E D + S + + + E+ QT T PR+ + D
Sbjct: 1081 IDAIEEIEIDLEETEREISPQENGLEEVKPLGEM--QTDLKATGREISPREKTPEVIDAT 1138
Query: 611 DALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAE 644
+ +DK + G+R+ P+EN P E K ++ + +
Sbjct: 1139 EEIDKDLEETGRREISPEENGPEEVKPVDEMETD 1172
Score = 32.7 bits (73), Expect = 1.3
Identities = 51/230 (22%), Positives = 90/230 (39%), Gaps = 28/230 (12%)
Query: 6 QKPAASPRPRRAA--AARRTHEHVSEKTSE-SPSKPGEK--KGSDEKKAASLGSSQSSRT 60
Q+ SPRP A +A + E T + ++P EK + S EK +SSR+
Sbjct: 28 QRGRESPRPPDPATDSASKPAEPTDVPTVDFGGAEPQEKAPRSSTEKTGGDNDVEESSRS 87
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDA 120
+ + ++S++S S S+ P+E+ + T ++ Q T + KQ
Sbjct: 88 SSTVSQRRKRISSTSSLVKSSVSV-PSESHPLSTINQEAPQPTATSTKEKQPCSDRYRIY 146
Query: 121 HNKKAVSRSAEQQPSEKS--------TEPKTKPQDMISAGGESVAGITAISGKPGDKKKE 172
+K E+ EK E + P + + + + ++E
Sbjct: 147 KAQKLREMLKEELRKEKKQWKNKYAINESQRPPDRSKMTMRDFIYYLPDNNPMTSSLEQE 206
Query: 173 KKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 222
KK+ P+ PV+++ + GKS +A E+ E E T GP
Sbjct: 207 KKTEKPSTPVQTR--EQEGKSTPNA------------EDNEMEEETDDGP 242
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 60.8 bits (146), Expect = 4e-09
Identities = 172/832 (20%), Positives = 300/832 (36%), Gaps = 121/832 (14%)
Query: 4 PGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAAS---LGSSQSSRT 60
PG+ +P + A A +T E+ SES S+ E S+E+ A+ L + S +T
Sbjct: 311 PGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE--ESSDSEEETPAAKALLQAKASGKT 368
Query: 61 YAGGTASA-TKVSASSGAT-SKSSSMNPTETKAVKTEPEKKSQSTKPKS-----LPKQAS 113
G ASA K S GA + P KA + E+ SQS+ +S P QA
Sbjct: 369 SQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAK 428
Query: 114 DTGSNDAHNKKAVSRSAEQQPSE--------------------KSTEPKTKPQDMISAGG 153
+G A +A S A++ P + K E + +
Sbjct: 429 PSGK--APQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDR 486
Query: 154 ESVAGITAISGKPGDKKKEKKSLTPAVPVESKP------DKPSGKSGMDAALDDLIDTLG 207
E++A + A KP K + K PA + P P GK G +
Sbjct: 487 EALAAMNAAQVKPLGKSPQVK---PASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEE 543
Query: 208 GPEETEEENTTYTGPEVSDPMSSTYIEELGK----REVTIPPKYRELLAKKEGITGPPAD 263
E + EE++ + EV ++ + LG + + P K +K G
Sbjct: 544 DSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP---PQKAGPVAVQVK 600
Query: 264 SSKPI----GPDDAIDALSSDFTCGSPTAA-GKKTEKEESTEVLKAQSAGTVRSAAPPQE 318
+ KP+ +++ D+ S+ + TAA K K T+ ++ T + P
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
Query: 319 KKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE------EKLEKCGE 372
+ + + + S ++ P D S +E D + K + + G+
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
Query: 373 DDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTE 432
+ + +K + + P+LP K P + +++ E ED + SE E
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLP---GKTGP-TVTQVKAEKQEDSESSE--------EE 768
Query: 433 KTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTV--PDDAVEALADSLGKKEAD- 489
E AA+PA V +V +T + +A P+ KGT+ P V A A + + +
Sbjct: 769 SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA-KGTISAPGKVVTAAAQAKQRSPSKV 827
Query: 490 --------------------PEDGKPVMDKVK-EKAKEEDREKLGEKEETIPPDYRLEEV 528
P GK V + + EED E+ ++ L +V
Sbjct: 828 KPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQV 887
Query: 529 KDKDGKPLLPKESKEQLPPMSEDFLLDA--LSEDFSGPQNASSLKFEDAKLAAAISEVVS 586
K GK + + L P E A +GP A + K +D+ ++ S+
Sbjct: 888 K-PSGK---THQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDG 943
Query: 587 QTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHR 646
+ PA+ T A D + A + + Q P + + E + +
Sbjct: 944 EAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESED 1003
Query: 647 DKLGERDDTIPPEYRHLLDDNGQDKPVKPP------------TKKSEDSKKPADDQDPID 694
+ + + P R + P P + + D KK +D
Sbjct: 1004 EDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVD 1063
Query: 695 ALSGDL--DSCPSTTETSQNT---AKDKCKKAASSSKAPKNGGKAKDSAKTT 741
+ G L S ST+ ++ T K K + ++KAP++ ++DS+ ++
Sbjct: 1064 SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSS 1115
Score = 59.7 bits (143), Expect = 1e-08
Identities = 154/769 (20%), Positives = 257/769 (33%), Gaps = 113/769 (14%)
Query: 35 PSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTETKAVKT 94
P+ P + G E+ + S SS+ S + G A + PT + A K
Sbjct: 531 PATPSAQVGKWEEDSES--SSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA-KG 587
Query: 95 EPEKKS------QSTKPKSLPKQASDTG-SNDAHNKKAVSRSAEQQPSEKSTEPKTKPQD 147
P+K ++ KP + + ++ S D+ A +A+ +P+ K + K P+
Sbjct: 588 PPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKK 647
Query: 148 MISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLG 207
+ VA + + P +K+ T P S P G D+
Sbjct: 648 TNTTASAKVAPVRVGTQAP------RKAGTATSPAGSSPAVAGGTQRPAE------DSSS 695
Query: 208 GPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPK------YRELLAKKEGITGPP 261
E EE T G V+ + + + L + ++P K +L K G T
Sbjct: 696 SEESDSEEEKT--GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQ 753
Query: 262 ADSSKPIGPDDAIDALSSDFTCGSPT---AAGKKTEKEESTEVLKAQSA-GTVRS----- 312
+ K + + + S+ SP + KKT+ + + +A SA GT+ +
Sbjct: 754 VKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVV 813
Query: 313 AAPPQEKKR---KVEKDTMSDQALEALS-------------ASLGTRQAEPELDLRSIKE 356
A Q K+R KV+ + Q L+ A+ Q PE D S +E
Sbjct: 814 TAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEE 873
Query: 357 VDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSE 416
+++ + E L + +T L PA + K P P K P +
Sbjct: 874 ESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQA------- 926
Query: 417 DFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAV 476
K+ S + + +S APA V+ A Q P P A
Sbjct: 927 ------GKQDDSGSSSEESDSDGEAPAAVTSA---------QVIKP-PLIFVDPNRSPAG 970
Query: 477 EALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKP- 535
A + + + P + + + E + E + + + P R V P
Sbjct: 971 PAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPR 1030
Query: 536 LLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQA 595
+ PK S E +S+ A+ + L A + S T +
Sbjct: 1031 IAPKASMAGASSSKES---SRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKL 1087
Query: 596 GAPP----RDTSQSDKDLDDALDKLSDSLGQRQPD--PDENKPMEDKV-----KEKAKAE 644
P + +++ + DD+ D S G + P K V + + E
Sbjct: 1088 RKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVE 1147
Query: 645 HRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCP 704
DD + P L +G P P P LDS P
Sbjct: 1148 ETAAESSEDDVVAPSQSLL---SGYMTPGLTPANSQASKATPK------------LDSSP 1192
Query: 705 STTET----SQNTAKDKCK-KAASSSKAPKNGGKAKDSAKTTEETSKPK 748
S + T K + K + A+ +PK GGK S T +++ KPK
Sbjct: 1193 SVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK 1241
Score = 45.4 bits (106), Expect = 2e-04
Identities = 145/758 (19%), Positives = 260/758 (34%), Gaps = 81/758 (10%)
Query: 12 PRPRRAAAARRTHEHVSEKTSESP---SKPGEKKGSDEKKAASLGSSQSSRTYAGGTASA 68
P + A ++ SE+ S+S + P + K S +K A + + A GT SA
Sbjct: 749 PTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISA 808
Query: 69 TKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTK-PKSLPKQASDTGSNDAHNKKAVS 127
++ A +K S P++ K P+ + + P S+P KAV+
Sbjct: 809 PGKVVTAAAQAKQRS--PSKVKPPVRNPQNSTVLARGPASVPSVG-----------KAVA 855
Query: 128 RSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKE-KKSLTPAV--PVES 184
+A+ Q + ++ + E++A + KP K + + +L PA P +
Sbjct: 856 TAAQAQTGPEEDSGSSEEESDSEEEAETLAQV-----KPSGKTHQIRAALAPAKESPRKG 910
Query: 185 KPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 244
P GK+G AA D G E + + P + T + + + +
Sbjct: 911 AAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDG-------EAPAAVTSAQVIKPPLIFVD 963
Query: 245 PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 304
P GP A ++ A +S+ T S ++ + + +T+ L
Sbjct: 964 PN--------RSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTP 1015
Query: 305 QSAGTVRSAAPPQEKKRKVEKDTMS--DQALEALSASLGTRQAEPELDLRSIKEVDEAKA 362
V P R K +M+ + E+ S G +Q P +VD A
Sbjct: 1016 GIRTNV--VTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPAT------QVDSA-- 1065
Query: 363 KEEKLEKCGEDDETIPSEYRLKP-ATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRS 421
G T P ++ T+K KP LPE ++ K S+ ++ S+ S
Sbjct: 1066 -------VGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGS 1118
Query: 422 ECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQS--APPEPATLKGTVPDDAVEAL 479
E + + + P+ V T+ S + P + L G + A
Sbjct: 1119 EEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA- 1177
Query: 480 ADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET---IPPDYRLEEVKDKDGKPL 536
+S K D P + + D ++ + ++ + P +E
Sbjct: 1178 -NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQK 1236
Query: 537 LPKESKEQLPPMSEDFLLDA-LSEDFSG---PQNASSLKFEDAKLAAAISEVVSQTPAST 592
K K P + L + +++ G P N + ++ K+ + E + T
Sbjct: 1237 SRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDT 1296
Query: 593 TQAGAPPRDTSQSDKDLDDA------LDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHR 646
T+ + S+ K D K LG + P + K KA+ R
Sbjct: 1297 TKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAK-R 1355
Query: 647 DKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPST 706
DK D + + L G + +K + + D +P + S
Sbjct: 1356 DKAS--GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNP-KSKKEKKKSDKRK 1412
Query: 707 TETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEET 744
+ + K K KKA++ + K K KT E+T
Sbjct: 1413 KDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1450
Score = 43.1 bits (100), Expect = 0.001
Identities = 93/447 (20%), Positives = 159/447 (35%), Gaps = 53/447 (11%)
Query: 334 EALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLE-KCGEDDETIPSEYRLKPATDKDGK 392
+A S+S T + E D+ V A+ K + K + P+ ++ T +
Sbjct: 195 QADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKG 254
Query: 393 PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPS-KPTEKTEESKAA-APAPVSEAVC 450
LP + KP ESE +E SE + + + K +EK + +AA APA +
Sbjct: 255 GALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPG-- 312
Query: 451 RTSMCSIQSAPPEPATLKGTVPDDA----VEALADSLGKKEADPEDGKPVMDKVKEKAKE 506
+ A P P G V E ++S ++ +D E+ P + +
Sbjct: 313 -------KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKAS 365
Query: 507 EDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQN 566
++G R GK P +K Q ED + D
Sbjct: 366 GKTSQVGAASAPAKESPRKGAAPAPPGK-TGPAVAKAQAGKREEDSQSSSEESDSEEEAP 424
Query: 567 ASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTS------QSDKDLDDALDKLSDSL 620
A + A A S ++P A APPR T Q K +D+ +S
Sbjct: 425 AQAKPSGKAPQVRAASAPAKESPRKGA-APAPPRKTGPAAAQVQVGKQEEDSRSSSEESD 483
Query: 621 GQRQP----DPDENKPMEDKVKEK-AKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKP 675
R+ + + KP+ + K A LG+ +PP G+ P P
Sbjct: 484 SDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPP---------GKVGPATP 534
Query: 676 PT---KKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPK--- 729
K EDS+ +++ D+ G++ + + + + K +S +K P
Sbjct: 535 SAQVGKWEEDSESSSEESS--DSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKA 592
Query: 730 -------NGGKAKDSAKTTEETSKPKD 749
K D+++++EE+S D
Sbjct: 593 GPVAVQVKAEKPMDNSESSEESSDSAD 619
Score = 37.4 bits (85), Expect = 0.051
Identities = 66/325 (20%), Positives = 117/325 (36%), Gaps = 54/325 (16%)
Query: 4 PGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAG 63
PG PA S + +A + VS + G+++ ++ A L + A
Sbjct: 1172 PGLTPANS-QASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAAS 1230
Query: 64 GTASATKVSASSGATSKSSS---MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDA 120
GT GA + +S + T+ + +P +++ S+ K ++ +
Sbjct: 1231 GTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQE- 1289
Query: 121 HNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAV 180
KK V + E S K E + + ++G + P KKK+K
Sbjct: 1290 -RKKVVDTTKES--SRKGWESRKR----------KLSGDQPAARTPRSKKKKKLG----- 1331
Query: 181 PVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKRE 240
+G+ G + PE+T +TT G D S E+ GK
Sbjct: 1332 ---------AGEGGEASV---------SPEKT---STTSKGKAKRDKASGDVKEKKGKGS 1370
Query: 241 VTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTE 300
L + P + K +G + D + + +K +KE+ +
Sbjct: 1371 ----------LGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEK 1420
Query: 301 VLKAQSAGTVRSAAPPQEKKRKVEK 325
KA+ A T S +P Q+KK+K +K
Sbjct: 1421 KKKAKKASTKDSESPSQKKKKKKKK 1445
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.298 0.120 0.321
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,124,525
Number of Sequences: 37866
Number of extensions: 1890109
Number of successful extensions: 14975
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 171
Number of HSP's successfully gapped in prelim test: 1080
Number of HSP's that attempted gapping in prelim test: 9180
Number of HSP's gapped (non-prelim): 4828
length of query: 750
length of database: 18,247,518
effective HSP length: 110
effective length of query: 640
effective length of database: 14,082,258
effective search space: 9012645120
effective search space used: 9012645120
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.