Search of human proteins with 109255249

Search of human proteins with 109255249

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|109255249 keratin 4 [Homo sapiens]
         (594 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|109255249 keratin 4 [Homo sapiens]                                1155   0.0  
gi|119395754 keratin 5 [Homo sapiens]                                 654   0.0  
gi|5031839 keratin 6A [Homo sapiens]                                  642   0.0  
gi|109148552 keratin 3 [Homo sapiens]                                 641   0.0  
gi|155969697 keratin 6C [Homo sapiens]                                639   0.0  
gi|119703753 keratin 6B [Homo sapiens]                                638   0.0  
gi|153791158 keratin 75 [Homo sapiens]                                628   e-180
gi|153791670 keratin 76 [Homo sapiens]                                614   e-176
gi|119395750 keratin 1 [Homo sapiens]                                 600   e-172
gi|194018511 keratin 77 [Homo sapiens]                                584   e-167
gi|47132620 keratin 2 [Homo sapiens]                                  583   e-166
gi|32567786 keratin 6L [Homo sapiens]                                 580   e-165
gi|28173564 keratin 73 [Homo sapiens]                                 578   e-165
gi|148612803 keratin 6 irs4 [Homo sapiens]                            565   e-161
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       564   e-161
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      564   e-161
gi|15618995 keratin 71 [Homo sapiens]                                 563   e-160
gi|89357932 keratin 5b [Homo sapiens]                                 501   e-142
gi|4504919 keratin 8 [Homo sapiens]                                   490   e-138
gi|67782365 keratin 7 [Homo sapiens]                                  486   e-137
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    451   e-127
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      440   e-123
gi|4504935 keratin 85 [Homo sapiens]                                  422   e-118
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   404   e-113
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   404   e-113
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   404   e-113
gi|14318422 keratin 86 [Homo sapiens]                                 404   e-113
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   402   e-112
gi|169790841 keratin 83 [Homo sapiens]                                401   e-111
gi|27477127 keratin 82 [Homo sapiens]                                 400   e-111

>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score = 1155 bits (2989), Expect = 0.0
 Identities = 594/594 (100%), Positives = 594/594 (100%)

Query: 1   MTSVGVFSDMLNGCGKDGLVPRAKPRDVSDFSLYAPATKPCCSRTYKRRRLRAPALTGLG 60
           MTSVGVFSDMLNGCGKDGLVPRAKPRDVSDFSLYAPATKPCCSRTYKRRRLRAPALTGLG
Sbjct: 1   MTSVGVFSDMLNGCGKDGLVPRAKPRDVSDFSLYAPATKPCCSRTYKRRRLRAPALTGLG 60

Query: 61  PVTSLIAPSSLSAAMIARQQCVRGGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGG 120
           PVTSLIAPSSLSAAMIARQQCVRGGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGG
Sbjct: 61  PVTSLIAPSSLSAAMIARQQCVRGGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGG 120

Query: 121 FGSRSLYNLRGNKSISMSVAGSRQGACFGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPA 180
           FGSRSLYNLRGNKSISMSVAGSRQGACFGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPA
Sbjct: 121 FGSRSLYNLRGNKSISMSVAGSRQGACFGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPA 180

Query: 181 GGIQEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLE 240
           GGIQEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLE
Sbjct: 181 GGIQEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLE 240

Query: 241 TKWNLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTK 300
           TKWNLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTK
Sbjct: 241 TKWNLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTK 300

Query: 301 YEEEINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTH 360
           YEEEINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTH
Sbjct: 301 YEEEINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTH 360

Query: 361 VSDTSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGD 420
           VSDTSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGD
Sbjct: 361 VSDTSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGD 420

Query: 421 NLKNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEA 480
           NLKNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEA
Sbjct: 421 NLKNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEA 480

Query: 481 ALQQAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGS 540
           ALQQAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGS
Sbjct: 481 ALQQAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGS 540

Query: 541 TSTGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGSSSSKIISTTTLNKRR 594
           TSTGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGSSSSKIISTTTLNKRR
Sbjct: 541 TSTGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGSSSSKIISTTTLNKRR 594


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  654 bits (1688), Expect = 0.0
 Identities = 360/575 (62%), Positives = 427/575 (74%), Gaps = 65/575 (11%)

Query: 84  GGPRGFSCGSAIVGGGKRGAFSSVSMSGG-----------AGRCSSGGFGSRSLYNLRGN 132
           GG R FS  SAI     R +F+SVS SGG           AG C  GG+GSRSLYNL G+
Sbjct: 12  GGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRSLYNLGGS 71

Query: 133 KSISMSVAG----SRQGACFGGAGGFGTG-----GFGGGFGGSFS---------GKGGPG 174
           K IS+S +G    +R GA  GG  GFG G     GFGGG GG F          G GGPG
Sbjct: 72  KRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPG 131

Query: 175 FPVCPAGGIQEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQ 234
           FPVCP GGIQEVT+NQSLLTPL+++IDP IQ+VRTEEREQIK LNNKFASFIDKV+FLEQ
Sbjct: 132 FPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQ 191

Query: 235 QNKVLETKWNLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSV 294
           QNKVL+TKW LLQ+Q T T  +NLEPLFE Y++ LR+QLD++  ++GRL SEL+ MQD V
Sbjct: 192 QNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLV 251

Query: 295 EDFKTKYEEEINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAEL 354
           EDFK KYE+EINKRT AEN+FV+LKKDVDAAY+NKVELEAKVD+L DEINF+K+ +DAEL
Sbjct: 252 EDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAEL 311

Query: 355 SQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQIS 414
           SQMQTHVSDTSVVLSMDNNRNLDLDSIIAEV+AQYEEIA RS+ EAE+ YQTK ++LQ +
Sbjct: 312 SQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQT 371

Query: 415 VDQHGDNLKNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSK 474
             +HGD+L+NTK EI+E+NRMIQRLRAEI+N+KKQC  LQ ++ADAEQRGE ALKDA +K
Sbjct: 372 AGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNK 431

Query: 475 RVELEAALQQAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSI 534
             ELE ALQ+AK+++AR+LREYQELM+ KLALD+EIATYRKLLEGEE R+SGE    V+I
Sbjct: 432 LAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNI 491

Query: 535 SVVSGSTST---------GGISGGLGSGSGFGLS-------------------------S 560
           SVV+ S S+         GG+ GGLG G G GL+                         S
Sbjct: 492 SVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVGLGGGLSVGGS 551

Query: 561 GFGSGSGSGFGFG-GSVSGSSSS-KIISTTTLNKR 593
           GF + SG G G G GS  GSSSS K +STT+ +++
Sbjct: 552 GFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSSRK 586


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  642 bits (1655), Expect = 0.0
 Identities = 352/544 (64%), Positives = 412/544 (75%), Gaps = 36/544 (6%)

Query: 87  RGFSCGSAIVGGGKRGAFSSVSMS------GGAGRCSSGGFGSRSLYNLRGNKSISMSVA 140
           RGFS  SA + G  R  FSSVS+S      G  G C   GFGSRSLY L G+K IS+   
Sbjct: 16  RGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGG 75

Query: 141 --------GSRQGAC--FGGAG---GFGTG---GFG-GGFGGSFSGKGGPGFPVCPAGGI 183
                   GSR G    FGGAG   GFG G   GFG GG  G   G GGPGFPVCP GGI
Sbjct: 76  SCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGI 135

Query: 184 QEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKW 243
           QEVT+NQSLLTPL+++IDP IQ+VR EEREQIK LNNKFASFIDKV+FLEQQNKVLETKW
Sbjct: 136 QEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKW 195

Query: 244 NLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEE 303
            LLQ+Q T T  +NLEPLFE Y++ LR+QLD++  ++GRL SEL+ MQD VEDFK KYE+
Sbjct: 196 TLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYED 255

Query: 304 EINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSD 363
           EINKRTAAEN+FV LKKDVDAAY+NKVEL+AK D+L DEINFL+ LYDAELSQMQTH+SD
Sbjct: 256 EINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISD 315

Query: 364 TSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLK 423
           TSVVLSMDNNRNLDLDSIIAEV+AQYEEIAQRS+AEAE+ YQTK ++LQ++  +HGD+L+
Sbjct: 316 TSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLR 375

Query: 424 NTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQ 483
           NTK EIAE+NRMIQRLR+EI+++KKQC  LQ ++ADAEQRGE ALKDA +K   LE ALQ
Sbjct: 376 NTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQ 435

Query: 484 QAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTST 543
           +AK++LAR+L+EYQELM+VKLALD+EIATYRKLLEGEE R++GE    V+ISVV  + S+
Sbjct: 436 KAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSS 495

Query: 544 G-----GISGGLG--------SGSGFGLSSGFGSGSGSGFGFGGSVSGSSSSKIISTTTL 590
           G     G+  GLG         GSG G+  GF S SG   G G S  G  SS I  TTT 
Sbjct: 496 GYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGSSTIKYTTTS 555

Query: 591 NKRR 594
           +  R
Sbjct: 556 SSSR 559


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  641 bits (1654), Expect = 0.0
 Identities = 365/563 (64%), Positives = 418/563 (74%), Gaps = 71/563 (12%)

Query: 84  GGPRGFSCGSAIVGGGKRGAFSSVSMSGGAG------RCSSGGFGSRSLYNLRGNKSISM 137
           GG +GFS  SA+V G  R   S V+ SGGAG      R  +GGFGSRSLYNL GNKSIS+
Sbjct: 11  GGSQGFSGRSAVVSGSSR--MSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISI 68

Query: 138 SVA--GSRQG-------AC-------------------------------------FGGA 151
           SVA  GSR G       +C                                     FGGA
Sbjct: 69  SVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGA 128

Query: 152 GGFG-TGGFGG--GFGGSFSGKGGPGFPVCPAG--------GIQEVTINQSLLTPLHVEI 200
           GGFG  GGFGG  GFGGS  G GGPG    P G        GIQEVTINQSLL PL+VEI
Sbjct: 129 GGFGGAGGFGGPGGFGGS-GGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQPLNVEI 187

Query: 201 DPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSS--KNL 258
           DP+I +V+ +EREQIK LNNKFASFIDKV+FLEQQNKVLETKWNLLQQQ T++ S   NL
Sbjct: 188 DPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNL 247

Query: 259 EPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVL 318
           EPLFE +++ LR  LD +  ++GRL SELK M+D VEDFK KYE+EINKRTAAEN+FV L
Sbjct: 248 EPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTL 307

Query: 319 KKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDL 378
           KKDVD+AY+NKVEL+AKVD+L DEI+FL+ LYDAELSQMQ+H+SDTSVVLSMDNNR+LDL
Sbjct: 308 KKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDL 367

Query: 379 DSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQR 438
           DSIIAEVRAQYE+IAQRSKAEAEALYQTK+ +LQ +  +HGD+L+NTKSEI ELNRMIQR
Sbjct: 368 DSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQR 427

Query: 439 LRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQE 498
           LRAEIE +KKQ   LQ ++A+AEQ GE ALKDA++K  EL+AALQQAK++LAR+LR+YQE
Sbjct: 428 LRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQE 487

Query: 499 LMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGST---STGGISGGLGSGSG 555
           LM+VKLALD+EIATYRKLLEGEEYRMSGEC SAVSISVVS ST   S GG  GG G G G
Sbjct: 488 LMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGYGGGMG 547

Query: 556 FGLSSGFGSGSGSGFGFGGSVSG 578
            GL  GF +G GSG GFG    G
Sbjct: 548 GGLGGGFSAGGGSGSGFGRGGGG 570



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 33/113 (29%), Positives = 43/113 (38%), Gaps = 15/113 (13%)

Query: 60  GPVTSLIAPSSLSAAMIARQQCVRGGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSG 119
           G   S ++ S +S++  +      GG  G   G  + GG   G  S      G G    G
Sbjct: 515 GECPSAVSISVVSSSTTSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGG 574

Query: 120 GFGSRSLYNLRGNKSISMSVAGSRQGACFGGAGGFGTGGFGGGFGGSFSGKGG 172
           GFG  S              +G   G+ FG   G   G  GGGF  S S +GG
Sbjct: 575 GFGGGS--------------SGFSGGSGFGSISGARYGVSGGGF-SSASNRGG 612



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 29/73 (39%), Positives = 33/73 (45%), Gaps = 3/73 (4%)

Query: 103 AFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAG-SRQGACFGGAGGFGTGGFGG 161
           A S   +S      S+GG+G      + G      S  G S  G   GG GG G GGFGG
Sbjct: 520 AVSISVVSSSTTSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIG-GGFGG 578

Query: 162 GFGGSFSGKGGPG 174
           G  G FSG  G G
Sbjct: 579 GSSG-FSGGSGFG 590



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 28/79 (35%), Positives = 31/79 (39%), Gaps = 5/79 (6%)

Query: 98  GGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGACFGGAGGFGT- 156
           GG  G +    M GG G   S G GS S +   G   I     G   G  F G  GFG+ 
Sbjct: 536 GGYGGGYGG-GMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSG--FSGGSGFGSI 592

Query: 157 -GGFGGGFGGSFSGKGGPG 174
            G   G  GG FS     G
Sbjct: 593 SGARYGVSGGGFSSASNRG 611


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  639 bits (1647), Expect = 0.0
 Identities = 348/544 (63%), Positives = 412/544 (75%), Gaps = 36/544 (6%)

Query: 87  RGFSCGSAIVGGGKRGAFSSVSMS------GGAGRCSSGGFGSRSLYNLRGNKSISMSVA 140
           RGFS  SA + G  R  FSS+S+S      G  G C   GFGSRSLY L G+K IS+   
Sbjct: 16  RGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGG 75

Query: 141 --------GSRQGAC--FGGAG---GFGTG---GFG-GGFGGSFSGKGGPGFPVCPAGGI 183
                   GSR G    FGGAG   GFG G   GFG GG  G   G GGPGFPVCP GGI
Sbjct: 76  SCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGI 135

Query: 184 QEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKW 243
           QEVT+NQSLLTPL+++IDP IQ+VR EEREQIK LNNKFASFIDKV+FLEQQNKVL+TKW
Sbjct: 136 QEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKW 195

Query: 244 NLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEE 303
            LLQ+Q T T  +NLEPLFE Y++ LR+QLD++  ++GRL SEL+ MQD VED K KYE+
Sbjct: 196 TLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDLKNKYED 255

Query: 304 EINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSD 363
           EINKRTAAEN+FV LKKDVDAAY+NKVEL+AK D+L DEINFL+ LYDAELSQMQTH+SD
Sbjct: 256 EINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISD 315

Query: 364 TSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLK 423
           TSVVLSMDNNRNLDLDSIIAEV+AQYEEIAQRS+AEAE+ YQTK ++LQ++  +HGD+L+
Sbjct: 316 TSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLR 375

Query: 424 NTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQ 483
           NTK EIAE+NRMIQRLR+EI+++KKQC +LQ ++ADAEQRGE ALKDA +K   LE ALQ
Sbjct: 376 NTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMALKDAKNKLEGLEDALQ 435

Query: 484 QAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTST 543
           +AK++LAR+L+EYQELM+VKLALD+EIATYRKLLEGEE R++GE    V++SVV  + S+
Sbjct: 436 KAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNVSVVQSTISS 495

Query: 544 G-----GISGGLG--------SGSGFGLSSGFGSGSGSGFGFGGSVSGSSSSKIISTTTL 590
           G     G+  GLG         GSG G+  GF S SG   G G S  G  SS I  TTT 
Sbjct: 496 GYGGASGVGSGLGLGGGSSYSYGSGLGIGGGFSSSSGRAIGGGLSSVGGGSSTIKYTTTS 555

Query: 591 NKRR 594
           +  R
Sbjct: 556 SSSR 559


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  638 bits (1645), Expect = 0.0
 Identities = 350/544 (64%), Positives = 410/544 (75%), Gaps = 36/544 (6%)

Query: 87  RGFSCGSAIVGGGKRGAFSSVSMS------GGAGRCSSGGFGSRSLYNLRGNKSISMSVA 140
           RGFS  SA + G  R  FSS+S+S      G  G C   GFGSRSLY L G+K IS+   
Sbjct: 16  RGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGG 75

Query: 141 --------GSRQGAC--FGGAG---GFGTG---GFG-GGFGGSFSGKGGPGFPVCPAGGI 183
                   GSR G    FGGAG   GFG G   GFG GG  G   G GGPGFPVCP GGI
Sbjct: 76  SCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGI 135

Query: 184 QEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKW 243
           QEVT+NQSLLTPL+++IDP IQ+VR EEREQIK LNNKFASFIDKV+FLEQQNKVL+TKW
Sbjct: 136 QEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKW 195

Query: 244 NLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEE 303
            LLQ+Q T T  +NLEPLFE Y++ LR+QLD +  ++GRL SEL+ MQD VED K KYE+
Sbjct: 196 TLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVEDLKNKYED 255

Query: 304 EINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSD 363
           EINKRTAAEN+FV LKKDVDAAY+NKVEL+AK D+L DEINFL+ LYDAELSQMQTH+SD
Sbjct: 256 EINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISD 315

Query: 364 TSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLK 423
           TSVVLSMDNNRNLDLDSIIAEV+AQYEEIAQRS+AEAE+ YQTK ++LQI+  +HGD+L+
Sbjct: 316 TSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQITAGRHGDDLR 375

Query: 424 NTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQ 483
           NTK EIAE+NRMIQRLR+EI+++KKQC  LQ ++ADAEQRGE ALKDA +K   LE ALQ
Sbjct: 376 NTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQ 435

Query: 484 QAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTST 543
           +AK++LAR+L+EYQELM+VKLALD+EIATYRKLLEGEE R++GE    V+ISVV  + S+
Sbjct: 436 KAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSS 495

Query: 544 G-----GISGGLG--------SGSGFGLSSGFGSGSGSGFGFGGSVSGSSSSKIISTTTL 590
           G     G+  GLG         GSG G+  GF S SG   G G S  G  SS I  TTT 
Sbjct: 496 GYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRATGGGLSSVGGGSSTIKYTTTS 555

Query: 591 NKRR 594
           +  R
Sbjct: 556 SSSR 559


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  628 bits (1619), Expect = e-180
 Identities = 339/539 (62%), Positives = 417/539 (77%), Gaps = 32/539 (5%)

Query: 84  GGPRGFSCGSAIVGGGKRGAFSSVSM------SGGAGRCSSGG--FGSRSLYNLRGNKSI 135
           G  RGFS  SAI     R  FSSVS+      SGG GR SS G  FGSRSLYNL G K +
Sbjct: 12  GSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLYNLGGAKRV 71

Query: 136 SMSVAGSRQGACFGGAGG--FGTG---GFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQ 190
           S++  GS   + FGG     FG     G+GGG GG FSG   P FPVCP GGIQEVT+NQ
Sbjct: 72  SINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSG---PSFPVCPPGGIQEVTVNQ 128

Query: 191 SLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQT 250
           SLLTPLH++IDP IQ+VR EEREQIK LNNKFASFIDKV+FLEQQNKVLETKW LLQ+Q 
Sbjct: 129 SLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQG 188

Query: 251 TTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTA 310
           + T  +NLEPLF++Y S LR+QL+++  ++GRL++EL+ MQD VEDFK +YE+EINKRTA
Sbjct: 189 SRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTA 248

Query: 311 AENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSM 370
           AEN+FV LKKDVDAAY+NKVELEAKV SL +EINF+  ++DAELSQ+QT V DTSVVLSM
Sbjct: 249 AENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSM 308

Query: 371 DNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIA 430
           DNNRNLDLDSIIAEV+AQYE+IA RS+AEAE+ YQTK ++LQ++  +HGD+L+NTK EI+
Sbjct: 309 DNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIS 368

Query: 431 ELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELA 490
           E+NRMIQRLRAEI+++KKQC +LQ ++ADAEQRGE ALKDA +K V+LE ALQ+AK+++A
Sbjct: 369 EMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMA 428

Query: 491 RMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISG-- 548
           R+LREYQELM++KLALD+EIATYRKLLEGEE R+SGE  S V+ISVV+ + S+G  SG  
Sbjct: 429 RLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYGSGSS 488

Query: 549 ------GLGSGSGFGLSSGFGSGSGSGFGFGG-------SVSGSSSS-KIISTTTLNKR 593
                 GLG GSG+  ++  G   G+G G  G        + GS SS K +STT+ +++
Sbjct: 489 IGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSSVKFVSTTSSSQK 547


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  614 bits (1584), Expect = e-176
 Identities = 354/574 (61%), Positives = 413/574 (71%), Gaps = 74/574 (12%)

Query: 78  RQQCVR---GGPRGFSCGSAIVGGGKRGAFSSVSMSGGAG------RCSSGGFGSRSLYN 128
           RQ C +   G  +GFS  SA+V G  R   S V+ SGGAG      R  +G FGSRSLYN
Sbjct: 3   RQVCKKSFSGRSQGFSGRSAVVSGSSR--MSCVARSGGAGGGACGFRSGAGSFGSRSLYN 60

Query: 129 LRGNKSISMSVA----------GSRQGACFGGAGGFGTGG-FGGGFG------------- 164
           L  NKSIS+SVA          G R    F G  G G GG +GGGFG             
Sbjct: 61  LGSNKSISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAG 120

Query: 165 -----------------GSFSGKGG---PGFPVCPAGGIQEVTINQSLLTPLHVEIDPEI 204
                            GSF G GG    GFP    GGIQEV +NQSLL PL+VEIDP+I
Sbjct: 121 GFGGAGGFGGPGVFGGPGSFGGPGGFGPGGFP----GGIQEVIVNQSLLQPLNVEIDPQI 176

Query: 205 QKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFET 264
            +V+ +EREQIK LNNKFASFIDKV+FLEQQNKVLETKW LLQQQTT +   +LEP FE+
Sbjct: 177 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFES 236

Query: 265 YLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDA 324
           Y+S L KQLD+L  ++G L+ ELK+MQD VEDFK KYE+EINKRTAAEN+FV LKKDVDA
Sbjct: 237 YISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDA 296

Query: 325 AYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAE 384
           A++NKVEL+AKVDSL DE++FL+ LY+ ELSQMQ+H SDTSVVLSMDNNR LDL SIIAE
Sbjct: 297 AFMNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAE 356

Query: 385 VRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIE 444
           VRAQYEEIAQRSK+EAEALYQTK+ +LQ +  +HGD+L+NTKSEI ELNRMIQRLRAEIE
Sbjct: 357 VRAQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIE 416

Query: 445 NIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVKL 504
           N+KKQ   LQ ++A+AEQRGE ALKDA++K  +L+ ALQ+AK++LAR+LR+YQELM+VKL
Sbjct: 417 NVKKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKL 476

Query: 505 ALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISG------GLGSGSGFG- 557
           ALD+EIATYRKLLEGEE RMSGECQSAV ISVVS  TST G SG      G  SGSG G 
Sbjct: 477 ALDVEIATYRKLLEGEECRMSGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGG 536

Query: 558 --------LSSGFGSGSGSGFGFGGSVSGSSSSK 583
                    SSG+G   GSG G+GG  SGS+  +
Sbjct: 537 YKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGR 570



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 29/86 (33%), Positives = 37/86 (43%), Gaps = 1/86 (1%)

Query: 83  RGGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGS 142
           +GG    S     V GG    +  VS     GR SSG + S S  +  G    S+SV+ S
Sbjct: 538 KGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGGAG-SISVSHS 596

Query: 143 RQGACFGGAGGFGTGGFGGGFGGSFS 168
             G+  G     G  G+  G GGS S
Sbjct: 597 GMGSSSGSIQTSGGSGYKSGGGGSTS 622



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 10/80 (12%)

Query: 105 SSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGACFGGAGGFG------TGG 158
           S+V+ + G+   S G FG  S     G K  S S + S  G   G   G+G      TGG
Sbjct: 510 SNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGG 569

Query: 159 FG--GGFGGSFSGK--GGPG 174
            G  G +  S SG   GG G
Sbjct: 570 RGSSGSYQSSSSGSRLGGAG 589


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  600 bits (1548), Expect = e-172
 Identities = 339/558 (60%), Positives = 412/558 (73%), Gaps = 52/558 (9%)

Query: 76  IARQQCVRGGPR---GFSCGSA-IVGGGKRGAFSSVSMSGGAG-RCSS-----------G 119
           ++RQ   R G R   GFS GSA I+   +R   SS   SGG G R SS           G
Sbjct: 1   MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGG 60

Query: 120 GFGSRSLYNLRGNKSISMSVA-GSRQGACFGGA--------GGFGTGGFGGG-------- 162
           GFGSRSL NL G+KSIS+SVA G  +G+ FGG         GGFG GGFGGG        
Sbjct: 61  GFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFG 120

Query: 163 -FGGSFSGKGGPGF----------PVCPAGGIQEVTINQSLLTPLHVEIDPEIQKVRTEE 211
            FG    G GG GF          PVCP GGIQEVTINQSLL PL+VEIDPEIQKV++ E
Sbjct: 121 GFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSRE 180

Query: 212 REQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFETYLSVLRK 271
           REQIK LNN+FASFIDKV+FLEQQN+VL+TKW LLQQ  T+T + NLEP FE++++ LR+
Sbjct: 181 REQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRR 240

Query: 272 QLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYLNKVE 331
           ++D L +D+ RL SELK MQD VED++ KYE+EINKRT AEN+FV +KKDVD AY+ KV+
Sbjct: 241 RVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVD 300

Query: 332 LEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRAQYEE 391
           L+AK+D+L  EI+FL  LY AELSQMQT +S+T+V+LSMDNNR+LDLDSIIAEV+AQYE+
Sbjct: 301 LQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYED 360

Query: 392 IAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIKKQCQ 451
           IAQ+SKAEAE+LYQ+K ++LQI+  +HGD+++N+K EI+ELNR+IQRLR+EI+N+KKQ  
Sbjct: 361 IAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQIS 420

Query: 452 TLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVKLALDIEIA 511
            LQ S++DAEQRGENALKDA +K  +LE ALQQAKE+LAR+LR+YQELM+ KLALD+EIA
Sbjct: 421 NLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIA 480

Query: 512 TYRKLLEGEEYRMSGECQSAVSISV------VSGSTSTGGISGGLGS-GSGFGLSSG-FG 563
           TYR LLEGEE RMSGEC   VS+SV      +SG  S GG  GG GS GS +G   G +G
Sbjct: 481 TYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYG 540

Query: 564 SGSGSGFGFGGSVSGSSS 581
           SG G G G G   SG SS
Sbjct: 541 SGGGGGGGRGSYGSGGSS 558



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 38/102 (37%), Positives = 47/102 (46%), Gaps = 2/102 (1%)

Query: 85  GPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSRQ 144
           G  G S GS   GGG RG++ S   S G+G  S G  G    +   G+ S S    G   
Sbjct: 533 GSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSG 592

Query: 145 GACFGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEV 186
           G   G +GG G+G  GG  GGS  G+G     V  +GG   V
Sbjct: 593 GGGGGSSGGRGSG--GGSSGGSIGGRGSSSGGVKSSGGSSSV 632



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 30/90 (33%), Positives = 36/90 (40%), Gaps = 5/90 (5%)

Query: 93  SAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGACFGGAG 152
           + I GGG RG       SGG+   S GG      Y   G         GS   +   G G
Sbjct: 510 TTISGGGSRGGGGGGYGSGGSSYGSGGGS-----YGSGGGGGGGRGSYGSGGSSYGSGGG 564

Query: 153 GFGTGGFGGGFGGSFSGKGGPGFPVCPAGG 182
            +G+GG GGG G   SG    G+     GG
Sbjct: 565 SYGSGGGGGGHGSYGSGSSSGGYRGGSGGG 594



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 30/91 (32%), Positives = 34/91 (37%)

Query: 84  GGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSR 143
           GG RG   G    GG   G+      SGG G    G +GS       G  S      G  
Sbjct: 515 GGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGG 574

Query: 144 QGACFGGAGGFGTGGFGGGFGGSFSGKGGPG 174
            G+   G+   G  G  GG GG  SG  G G
Sbjct: 575 HGSYGSGSSSGGYRGGSGGGGGGSSGGRGSG 605



 Score = 32.7 bits (73), Expect = 0.97
 Identities = 20/54 (37%), Positives = 23/54 (42%), Gaps = 1/54 (1%)

Query: 539 GSTSTGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGSSSSKIISTTTLNK 592
           G    GGI GG   G G G   GFG G   G G+GG          I   T+N+
Sbjct: 107 GGFGGGGIGGGGFGGFGSG-GGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQ 159



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 32/87 (36%), Positives = 33/87 (37%), Gaps = 25/87 (28%)

Query: 84  GGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSR 143
           GG  G S GS    GG RG       SGG G  SSGG GS                 G  
Sbjct: 572 GGGHG-SYGSGSSSGGYRGG------SGGGGGGSSGGRGS----------------GGGS 608

Query: 144 QGACFGGAGGFGTGGFGGGFGGSFSGK 170
            G   GG G   +GG     GGS S K
Sbjct: 609 SGGSIGGRGS-SSGGVKSS-GGSSSVK 633


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  584 bits (1505), Expect = e-167
 Identities = 315/521 (60%), Positives = 391/521 (75%), Gaps = 33/521 (6%)

Query: 87  RGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGG-------FGSRSLYNLRGNKSISMSV 139
           R +S  S+   GG   A  SV  +   GRC  GG       FGSRSLYNL G++SIS+++
Sbjct: 17  RVYSTSSSAGSGGGSPAVGSVCYA--RGRCGGGGYGIHGRGFGSRSLYNLGGSRSISINL 74

Query: 140 AG-SRQGACFGG-----------------AGGFGTGGFGG-GFGGSFSGKGGPGFPVCPA 180
            G S  G C GG                 AGGFG GGFGG GFG S  G GG G P CP 
Sbjct: 75  MGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGGFG-PYCPP 133

Query: 181 GGIQEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLE 240
           GGIQEVTINQSLL PLH+E+DPEIQ+++T+EREQI +LNNKFASFIDKV+FLEQQN+VL+
Sbjct: 134 GGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQ 193

Query: 241 TKWNLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTK 300
           TKW LLQQ  T+T + NLEPL E Y+  LR+Q+D L  ++ R  +E+++MQD VED+K+K
Sbjct: 194 TKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSK 253

Query: 301 YEEEINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTH 360
           YE+EINKRT +ENDFVVLKKDVDAAY++KV+LE++VD+L  E+NFLK L+  ELSQ+QTH
Sbjct: 254 YEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTH 313

Query: 361 VSDTSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGD 420
           +SDT+V+LSMDNNR+LDLDSII  VR QYE IAQRSK EAEALYQTK Q+LQI+  +HGD
Sbjct: 314 ISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGD 373

Query: 421 NLKNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEA 480
           +LKN+K EIAELNR +QRL+AEI N+KKQ + +Q  ++DAE+RGE AL+DA  K  +LE 
Sbjct: 374 DLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEE 433

Query: 481 ALQQAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGS 540
           ALQQ+KEELAR+LR+YQ ++ VKL+LD+EIATYR+LLEGEE RMSGE QS VSISV +  
Sbjct: 434 ALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQ 493

Query: 541 TSTGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGSSS 581
            S   ++GG G G  +G S G+G GSG G+G G S  G  +
Sbjct: 494 VS---VNGGAGGGGSYG-SGGYGGGSGGGYGGGRSYRGGGA 530



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 35/107 (32%), Positives = 41/107 (38%), Gaps = 32/107 (29%)

Query: 69  SSLSAAMIARQQCVRGGPRGF-SCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLY 127
           S +S ++   Q  V GG  G  S GS   GGG  G +       G GR   GG       
Sbjct: 483 SHVSISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGY-------GGGRSYRGG------- 528

Query: 128 NLRGNKSISMSVAGSRQGACFGGAGGFGTGGFGGGFGGSFSGKGGPG 174
             RG                 GG  G G GG GG +GG  SG+ G G
Sbjct: 529 GARGRS---------------GGGYGSGCGGGGGSYGG--SGRSGRG 558


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  583 bits (1504), Expect = e-166
 Identities = 329/544 (60%), Positives = 393/544 (72%), Gaps = 49/544 (9%)

Query: 84  GGPRGFSCGSAIVGGGKRGAFSSVSM----SGGAGRCSSGGFGSRSLYNLRGNKSISMSV 139
           GG RGFS GSA+V GG R + SS S      GG G    GGFGSRSL  L G KSIS+SV
Sbjct: 17  GGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKSISISV 76

Query: 140 AGSRQG-----------------ACFGGAGGFGTGGFGGGF--GGSFSGKGGPGF----- 175
           AG   G                 + FGG  GF  GGFGGG   GG F G GGPG      
Sbjct: 77  AGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLG 136

Query: 176 ------PVCPAGGIQEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKV 229
                 P    GGI EV++NQSLL PL+V++DPEIQ V+ +EREQIK LNNKFASFIDKV
Sbjct: 137 GPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKV 196

Query: 230 QFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKT 289
           +FLEQQN+VL+TKW LLQQ    T   NLEP+F+ Y+  L++ LD L  ++    SEL  
Sbjct: 197 RFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNN 256

Query: 290 MQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVL 349
           MQD VED+K KYE+EINKRTAAENDFV LKKDVD AY+ KVEL++KVD LN EI FLKVL
Sbjct: 257 MQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVL 316

Query: 350 YDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQ 409
           YDAE+SQ+   V+DT+V+LSMDN+RNLDLDSIIAEV+AQYEEIAQRSK EAEALY +K +
Sbjct: 317 YDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYE 376

Query: 410 QLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALK 469
           +LQ++V +HGD+LK  K EI+ELNR+IQRL+ EI ++KKQC+ +Q ++ADAEQRGE+ALK
Sbjct: 377 ELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALK 436

Query: 470 DAHSKRVELEAALQQAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQ 529
           DA +K  +LE ALQQAKE+LAR+LR+YQELM+VKLALD+EIATYRKLLEGEE RMSG+  
Sbjct: 437 DARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLS 496

Query: 530 SAVSISVVSGSTSTG-------GISGGLGSGSGFGLSSG---FGSG---SGS--GFGFGG 574
           S V++SV S + S+        G SGG GS SG G SSG   +GSG   SGS  G G GG
Sbjct: 497 SNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGG 556

Query: 575 SVSG 578
           S+SG
Sbjct: 557 SISG 560



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 42/121 (34%), Positives = 58/121 (47%), Gaps = 19/121 (15%)

Query: 62  VTSLIAPSSLSAAMIARQQCVRGGPRG------FSCGSAIVGGGKRGAFSSVSMSGGAGR 115
           VT  +  S++S+ + ++      G RG      +S GS+  G G R +  S   SGG G 
Sbjct: 499 VTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQS-GSRGGSGGGGS 557

Query: 116 CSSGGFGSRSLYNLRGNKSISMSVAGSRQGACFGGAGGFGTGG-----FGGGFGGSFSGK 170
            S GG+GS       G+     S  GS+ G+  GG  G+G+GG      GG  GGS SG 
Sbjct: 558 ISGGGYGSGG-----GSGGRYGSGGGSKGGSISGG--GYGSGGGKHSSGGGSRGGSSSGG 610

Query: 171 G 171
           G
Sbjct: 611 G 611



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 34/92 (36%), Positives = 40/92 (43%), Gaps = 9/92 (9%)

Query: 83  RGGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGS 142
           + G RG S G   + GG  G+        G+G  S GG  S   Y   G K    S  GS
Sbjct: 545 QSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGK--HSSGGGS 602

Query: 143 RQGACFGGAGGFGTGGFGGGFGGSFSGKGGPG 174
           R G+  G       GG+G G GGS S KG  G
Sbjct: 603 RGGSSSG-------GGYGSGGGGSSSVKGSSG 627



 Score = 32.7 bits (73), Expect = 0.97
 Identities = 18/34 (52%), Positives = 18/34 (52%)

Query: 538 SGSTSTGGISGGLGSGSGFGLSSGFGSGSGSGFG 571
           SG  S GG S G G GSG G SS     SG  FG
Sbjct: 598 SGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEAFG 631


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  580 bits (1496), Expect = e-165
 Identities = 329/523 (62%), Positives = 389/523 (74%), Gaps = 26/523 (4%)

Query: 88  GFSCGSAIVGGGK--RGAFSSVSMS-----GGAGRCS--SGGFGSRSLYNLRGNKSISMS 138
           GFS  SA  G G   R +FSSV++S     GG   C   +GGFGSRSLYNL G+KSIS+S
Sbjct: 15  GFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSLYNLGGHKSISVS 74

Query: 139 VAGSRQGACFGGA-GGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLH 197
           VAG   GA  G A GGFG G     F G  +G+   G P CP GGIQEVT+NQSLLTPLH
Sbjct: 75  VAG---GALLGRALGGFGFGS--RAFMGQGAGRQTFG-PACPPGGIQEVTVNQSLLTPLH 128

Query: 198 VEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTT--TSS 255
           VEIDPEIQ+VRT+EREQIK LNNKFASFIDKV+FLEQQNKVLETKW LLQ+Q      + 
Sbjct: 129 VEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTR 188

Query: 256 KNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDF 315
            NLEPLFE YL  +R  LD L +++GRL SEL+ +QD VEDFK KYE+EINK TAAEN+F
Sbjct: 189 NNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEF 248

Query: 316 VVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRN 375
           VVLKKDVDAAY+ +++L  KV +L  EI+FL+ LY+ ELSQ+QTHVS+T+VVLSMDNNRN
Sbjct: 249 VVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRN 308

Query: 376 LDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRM 435
           LDLDSIIAEV+AQYE IAQRS+AEAEA YQTK ++LQ++  +HGDNL++TK+EIAEL R 
Sbjct: 309 LDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRT 368

Query: 436 IQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLRE 495
           IQRL+ E +  KKQCQ LQ ++A+AEQRGE ALKDA  K  +L+ AL QAKE+L R+LR+
Sbjct: 369 IQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRD 428

Query: 496 YQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGG-----ISGGL 550
           YQELM+VKLALD+EIATYRKLLE EE RMSGEC SAVSISV   ST+  G       GG+
Sbjct: 429 YQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTTVCGGGAASFGGGI 488

Query: 551 G-SGSGFGLSSGFGSGSGSGFGFGGSVSGSSSSKIISTTTLNK 592
              GSG     GF +  G     GG VS  +S  I+  TT  K
Sbjct: 489 SLGGSGGATKGGFSTNVGYSTVKGGPVSAGTS--ILRKTTTVK 529


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score =  578 bits (1491), Expect = e-165
 Identities = 319/506 (63%), Positives = 392/506 (77%), Gaps = 29/506 (5%)

Query: 88  GFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGAC 147
           GFS  SA++ GG     SS   +GG G   SGGF SRSLY+L G +SIS +VA       
Sbjct: 16  GFSGCSAVLSGGS----SSSYRAGGKGL--SGGFSSRSLYSLGGARSISFNVASGS---- 65

Query: 148 FGGAGGFGTG-GFGGGFGGSFSGKGGPGF---PVCPAGGIQEVTINQSLLTPLHVEIDPE 203
            G AGG+G G G   GF GS  G    G     +CP GGI +VTIN+SLL PL+VE+DPE
Sbjct: 66  -GWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELDPE 124

Query: 204 IQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFE 263
           IQKVR +EREQIK+LNNKFASFIDKV+FLEQQN+VLETKW LLQQ        NLEP+ E
Sbjct: 125 IQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILE 184

Query: 264 TYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVD 323
            Y+S LRKQL+TL  D+ RL SEL+++++ VED+K +YEEEINKRT AEN+FVVLKKDVD
Sbjct: 185 GYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVD 244

Query: 324 AAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIA 383
           AAY +KVEL+AKVD+L+ EI F K LY+ E +Q+Q+H+SDTS++LSMDNNRNLDLDSIIA
Sbjct: 245 AAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIA 304

Query: 384 EVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEI 443
           EVRAQYEEIA++SKAEAEALYQTK Q+LQ++  +HGD+LK+TK+EI+EL R+IQRLR+EI
Sbjct: 305 EVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEI 364

Query: 444 ENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVK 503
           E++KKQC  L+ ++ADAEQRG+ ALKDA +K  ELE ALQQAKEELARMLREYQEL+SVK
Sbjct: 365 ESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLSVK 424

Query: 504 LALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLSS--- 560
           L+LDIEIATYRKLLEGEE RMSGE  ++VSISV++ S     ++G  G+G+GFG S+   
Sbjct: 425 LSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSS-----MAGMAGTGAGFGFSNAGT 479

Query: 561 -GFGSGSGSGFGF----GGSVSGSSS 581
            G+   S SG G+    GG V+GS +
Sbjct: 480 YGYWPSSVSG-GYSMLPGGCVTGSGN 504


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  565 bits (1455), Expect = e-161
 Identities = 309/495 (62%), Positives = 375/495 (75%), Gaps = 20/495 (4%)

Query: 84  GGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSR 143
           G    FS  SA+V    R A  S++    AGR +  GFGSRSLY+L GN+ IS +VAG  
Sbjct: 11  GDKGNFSVHSAVV---PRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGG- 66

Query: 144 QGACFGGAGGFGTGGFGGGFGGSFSGK-------GGPGFPVCPAGGIQEVTINQSLLTPL 196
            G   GG G     G+GGG    F+G        G     VCP GGI +VT+N+SLL PL
Sbjct: 67  -GVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPL 125

Query: 197 HVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSK 256
           +VE+DPEIQKVR +EREQIK+LN+KFASFIDKV+FLEQQN+VLETKW LLQQ       K
Sbjct: 126 NVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKK 185

Query: 257 NLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFV 316
           NLEP+ E Y+S LRKQL+TL  D+ RL SEL++M+D VED+K +YE EIN+RT AEN+FV
Sbjct: 186 NLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFV 245

Query: 317 VLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNL 376
           VLKKD DAAY  KVEL+AKVDSL+ EI FLK LYDAE++Q+QTH S+TSV+LSMDNNR+L
Sbjct: 246 VLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDL 305

Query: 377 DLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMI 436
           DLDSIIAEVR  YEEIA +SKAEAEALYQTK+Q+LQ++  +HGD+LK+T+SE+ ELNR+I
Sbjct: 306 DLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLI 365

Query: 437 QRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREY 496
           QR+R EI N+KKQ  +L+ ++ADAEQRG+NALKDA +K  ELE AL QAKEELARMLREY
Sbjct: 366 QRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREY 425

Query: 497 QELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGST------STGGISGGL 550
           QELMS+KLALD+EIATYRKLLEGEE RMSGE  S+VSISV+S S+      S+ G+   L
Sbjct: 426 QELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVD--L 483

Query: 551 GSGSGFGLSSGFGSG 565
           G+ +  G S    SG
Sbjct: 484 GASAVAGSSGSTQSG 498



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 14/34 (41%), Positives = 18/34 (52%)

Query: 546 ISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGS 579
           ++GG     G+G   G G G G   GF GS+ GS
Sbjct: 63  VAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGS 96


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  564 bits (1453), Expect = e-161
 Identities = 307/482 (63%), Positives = 370/482 (76%), Gaps = 20/482 (4%)

Query: 83  RGGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGS 142
           RG   GFS  SA++ GG      S S S  A    S  FGS+SL  L G++S+++S A  
Sbjct: 10  RGERLGFSGCSAVLSGG----IGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAAR 65

Query: 143 RQGACFGGAGGFGTGGFGGGFGGSFSGKG-GPGFP-VCPAGGIQEVTINQSLLTPLHVEI 200
           R           G G  GG  G +F   G GP  P VCP GGI +VT+N+SLL PL+VE+
Sbjct: 66  R-----------GGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEM 114

Query: 201 DPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEP 260
           DPEIQ+VR +EREQIK LNNKFASFIDKV+FLEQQN+VLETKWNLLQQ       KNLEP
Sbjct: 115 DPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEP 174

Query: 261 LFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKK 320
           ++E Y+S L+KQL+ L  D  RL SEL+ MQD VED+K +YE EIN+RTAAEN+FVVLKK
Sbjct: 175 IYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKK 234

Query: 321 DVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDS 380
           DVDAAY+NKVEL+AKVDSL DEI F K LY+ E++Q+Q+H+SDTS+VLSMDNNR+LDLDS
Sbjct: 235 DVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDS 294

Query: 381 IIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLR 440
           IIAEVRAQYEEIA +SKAEAE LYQTK+Q+LQ++  QHGD+LK TK+EI+ELNR+IQR+R
Sbjct: 295 IIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIR 354

Query: 441 AEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELM 500
           +EI N+KKQC  L+ ++ADAEQRG+ ALKDA +K  ELE AL QAKEELARMLREYQEL+
Sbjct: 355 SEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELV 414

Query: 501 SVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLSS 560
           S+KLALD+EIATYRKLLE EE RMSGE  ++VSISV+S   ST   +GG G   GFG SS
Sbjct: 415 SLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVIS---STNAGAGGAGFSMGFGASS 471

Query: 561 GF 562
            +
Sbjct: 472 SY 473


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  564 bits (1453), Expect = e-161
 Identities = 307/482 (63%), Positives = 370/482 (76%), Gaps = 20/482 (4%)

Query: 83  RGGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGS 142
           RG   GFS  SA++ GG      S S S  A    S  FGS+SL  L G++S+++S A  
Sbjct: 10  RGERLGFSGCSAVLSGG----IGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAAR 65

Query: 143 RQGACFGGAGGFGTGGFGGGFGGSFSGKG-GPGFP-VCPAGGIQEVTINQSLLTPLHVEI 200
           R           G G  GG  G +F   G GP  P VCP GGI +VT+N+SLL PL+VE+
Sbjct: 66  R-----------GGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEM 114

Query: 201 DPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEP 260
           DPEIQ+VR +EREQIK LNNKFASFIDKV+FLEQQN+VLETKWNLLQQ       KNLEP
Sbjct: 115 DPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEP 174

Query: 261 LFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKK 320
           ++E Y+S L+KQL+ L  D  RL SEL+ MQD VED+K +YE EIN+RTAAEN+FVVLKK
Sbjct: 175 IYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKK 234

Query: 321 DVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDS 380
           DVDAAY+NKVEL+AKVDSL DEI F K LY+ E++Q+Q+H+SDTS+VLSMDNNR+LDLDS
Sbjct: 235 DVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDS 294

Query: 381 IIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLR 440
           IIAEVRAQYEEIA +SKAEAE LYQTK+Q+LQ++  QHGD+LK TK+EI+ELNR+IQR+R
Sbjct: 295 IIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIR 354

Query: 441 AEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELM 500
           +EI N+KKQC  L+ ++ADAEQRG+ ALKDA +K  ELE AL QAKEELARMLREYQEL+
Sbjct: 355 SEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELV 414

Query: 501 SVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLSS 560
           S+KLALD+EIATYRKLLE EE RMSGE  ++VSISV+S   ST   +GG G   GFG SS
Sbjct: 415 SLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVIS---STNAGAGGAGFSMGFGASS 471

Query: 561 GF 562
            +
Sbjct: 472 SY 473


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  563 bits (1451), Expect = e-160
 Identities = 312/501 (62%), Positives = 382/501 (76%), Gaps = 21/501 (4%)

Query: 88  GFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGAC 147
           GFS  SA++ GG   +F + S         SGGFGSRSLY+L G +S++++ +GS     
Sbjct: 16  GFSGCSAVLSGGSSSSFRAGSKG------LSGGFGSRSLYSLGGVRSLNVA-SGS----- 63

Query: 148 FGGAGGFGTG-GFGGGFGGSFSGKG--GPGFP-VCPAGGIQEVTINQSLLTPLHVEIDPE 203
            G +GG+G G G   GF GS  G    GP  P VCP GGI +VT+N+SLL PL+VE+DPE
Sbjct: 64  -GKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPE 122

Query: 204 IQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFE 263
           IQKVR +EREQIK LNNKFASFIDKV+FLEQQN+VLETKW LLQQ        NLEP+ E
Sbjct: 123 IQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILE 182

Query: 264 TYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVD 323
            Y+S LRKQL+TL  D+ RL SEL+ ++D VED+K +YEEEINKRTAAEN+FV+LKKDVD
Sbjct: 183 GYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVD 242

Query: 324 AAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIA 383
           AAY NKVEL+AKV+S++ EI F + L++AE++Q+Q+H+SD SV+LSMDNNRNLDLDSII 
Sbjct: 243 AAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIID 302

Query: 384 EVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEI 443
           EVR QYEEIA +SKAEAEALYQTK Q+LQ++  +HGD+LKNTK+EI+EL R+IQR+R+EI
Sbjct: 303 EVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEI 362

Query: 444 ENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVK 503
           EN+KKQ   L+ ++ADAEQRG+NALKDA +K  ELE AL QAKEELARMLREYQELMS+K
Sbjct: 363 ENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLK 422

Query: 504 LALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISG---GLGSGSGFGLSS 560
           LALD+EIATYRKLLE EE RMSGE  S VSIS++S STS G + G    + SG     SS
Sbjct: 423 LALDMEIATYRKLLESEECRMSGEFPSPVSISIIS-STSGGSVYGFRPSMVSGGYVANSS 481

Query: 561 GFGSGSGSGFGFGGSVSGSSS 581
              SG  S  G  G   GS++
Sbjct: 482 NCISGVCSVRGGEGRSRGSAN 502



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 13/61 (21%)

Query: 535 SVVSGSTSTG------GISGGLGSGSGFGLSS------GFGSGSGSGFGFG-GSVSGSSS 581
           +V+SG +S+       G+SGG GS S + L          GSG   G+GFG G  SG + 
Sbjct: 22  AVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASGSGKSGGYGFGRGRASGFAG 81

Query: 582 S 582
           S
Sbjct: 82  S 82


>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score =  501 bits (1290), Expect = e-142
 Identities = 280/512 (54%), Positives = 352/512 (68%), Gaps = 34/512 (6%)

Query: 87  RGFSCGSAIVG---GGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSR 143
           RGFS  SA      G  RG FSS            GGF SRSL +               
Sbjct: 10  RGFSARSACSARSRGRSRGGFSS-----------RGGFSSRSLNSF-------------- 44

Query: 144 QGACFGGAGGFGTGGFGGGFGGSFSG-KGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDP 202
            G C  G+ G  T G GG  G  F    GGPG  +CP GGIQEVTINQ+LLTPL +EIDP
Sbjct: 45  -GGCLEGSRG-STWGSGGRLGVRFGEWSGGPGLSLCPPGGIQEVTINQNLLTPLKIEIDP 102

Query: 203 EIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLF 262
           + Q VRT+E ++I+ LNN+FASFIDKV+FLEQQNKVLETKW+LLQQQ  + S + LEP+F
Sbjct: 103 QFQVVRTQETQEIRTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVF 162

Query: 263 ETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDV 322
           E  L  LRKQL+ L  ++G L +ELK  +D  E++K+KYEEE ++R   ENDFVVLKKDV
Sbjct: 163 EACLDQLRKQLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDV 222

Query: 323 DAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSII 382
           D  +L+K+ELE K+++L + + FLK L + EL Q+QT  SDTSVVLSMDNNR LD  SII
Sbjct: 223 DGVFLSKMELEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSII 282

Query: 383 AEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAE 442
            EVRA+YEEIA+ SKAEAEALYQTK Q+LQ+S   HGD ++ TK +I++L++ IQRL+++
Sbjct: 283 TEVRARYEEIARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQ 342

Query: 443 IENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSV 502
            EN+KKQ  +LQ ++ DAEQRGE ALKDA +K  ELEAAL+ AK+ LAR+L EYQEL S 
Sbjct: 343 TENLKKQNASLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTST 402

Query: 503 KLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGS-TSTGGISGGLGSGSGFGLSSG 561
           KL+LD+EIATYR+LLEGEE RMSGEC S V+IS V GS   +GG+ GGLGS  G G   G
Sbjct: 403 KLSLDVEIATYRRLLEGEECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKG 462

Query: 562 FGSGSGSGFGFGGS--VSGSSSSKIISTTTLN 591
                 +    GGS  + GS    ++ + +++
Sbjct: 463 SPGSCCTSIVTGGSNIILGSGKDPVLDSCSVS 494


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  490 bits (1261), Expect = e-138
 Identities = 258/439 (58%), Positives = 337/439 (76%), Gaps = 11/439 (2%)

Query: 155 GTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDPEIQKVRTEEREQ 214
           G+  F GG GG + G  G        GGI  VT+NQSLL+PL +E+DP IQ VRT+E+EQ
Sbjct: 42  GSSNFRGGLGGGYGGASG-------MGGITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQ 94

Query: 215 IKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFETYLSVLRKQLD 274
           IK LNNKFASFIDKV+FLEQQNK+LETKW+LLQQQ T  S  N++ +FE+Y++ LR+QL+
Sbjct: 95  IKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKTARS--NMDNMFESYINNLRRQLE 152

Query: 275 TLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYLNKVELEA 334
           TLG +K +L++EL  MQ  VEDFK KYE+EINKRT  EN+FV++KKDVD AY+NKVELE+
Sbjct: 153 TLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELES 212

Query: 335 KVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQ 394
           +++ L DEINFL+ LY+ E+ ++Q+ +SDTSVVLSMDN+R+LD+DSIIAEV+AQYE+IA 
Sbjct: 213 RLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIAN 272

Query: 395 RSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIKKQCQTLQ 454
           RS+AEAE++YQ K ++LQ    +HGD+L+ TK+EI+E+NR I RL+AEIE +K Q  +L+
Sbjct: 273 RSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLE 332

Query: 455 VSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVKLALDIEIATYR 514
            ++ADAEQRGE A+KDA++K  ELEAALQ+AK+++AR LREYQELM+VKLALDIEIATYR
Sbjct: 333 AAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYR 392

Query: 515 KLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLSSGFGSGSGSGFGFGG 574
           KLLEGEE R+    Q+ +SI   + S   GG+S   G  +  GLS   GS  GSG G   
Sbjct: 393 KLLEGEESRLESGMQN-MSIHTKTTSGYAGGLSSAYGGLTSPGLSYSLGSSFGSGAG-SS 450

Query: 575 SVSGSSSSKIISTTTLNKR 593
           S S +SSS+ +    +  R
Sbjct: 451 SFSRTSSSRAVVVKKIETR 469


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  486 bits (1250), Expect = e-137
 Identities = 271/461 (58%), Positives = 346/461 (75%), Gaps = 17/461 (3%)

Query: 132 NKSISMSVAGSRQGACFGGAGGFGTGGFGGGFGGSF------SGKGGPGFPVCPAGGIQE 185
           ++S + S  G++        GG G+    G  G S       S  GGP        GI+E
Sbjct: 12  SRSAAFSGRGAQVRLSSARPGGLGSSSLYG-LGASRPRVAVRSAYGGP-----VGAGIRE 65

Query: 186 VTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNL 245
           VTINQSLL PL ++ DP +Q+VR EE EQIK LNNKFASFIDKV+FLEQQNK+LETKW L
Sbjct: 66  VTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTL 125

Query: 246 LQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEI 305
           LQ+Q +  SS+ L  +FE  ++ LR QL+ L  D GRL++EL++MQD VEDFK KYE+EI
Sbjct: 126 LQEQKSAKSSR-LPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEI 184

Query: 306 NKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTS 365
           N RTAAEN+FVVLKKDVDAAY++KVELEAKVD+LNDEINFL+ L + EL+++Q+ +SDTS
Sbjct: 185 NHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDTS 244

Query: 366 VVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNT 425
           VVLSMDN+R+LDLD IIAEV+AQYEE+A+ S+AEAEA YQTK + LQ    +HGD+L+NT
Sbjct: 245 VVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNT 304

Query: 426 KSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQA 485
           ++EI+E+NR IQRL+AEI+NIK Q   L+ ++A+AE+RGE ALKDA +K+ ELEAALQ+ 
Sbjct: 305 RNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRG 364

Query: 486 KEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVS---GSTS 542
           K+++AR LREYQELMSVKLALDIEIATYRKLLEGEE R++G+   AV+ISV++   GS+S
Sbjct: 365 KQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSS 424

Query: 543 TGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGSSSSK 583
            GGI   LG   G    S F S +G G     S+  +S+S+
Sbjct: 425 GGGIGLTLGGTMGSNALS-FSSSAGPGLLKAYSIRTASASR 464



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 17/44 (38%), Positives = 22/44 (50%)

Query: 131 GNKSISMSVAGSRQGACFGGAGGFGTGGFGGGFGGSFSGKGGPG 174
           G  ++++SV  S  G+  GG  G   GG  G    SFS   GPG
Sbjct: 407 GVGAVNISVMNSTGGSSSGGGIGLTLGGTMGSNALSFSSSAGPG 450


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  451 bits (1161), Expect = e-127
 Identities = 262/525 (49%), Positives = 348/525 (66%), Gaps = 41/525 (7%)

Query: 90  SCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGAC-- 147
           SC +       R   +SVS   G G    G FGSRS+    G+ S  ++  GSR   C  
Sbjct: 19  SCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITF-GSYSPRIAAVGSRPIHCGV 77

Query: 148 ---------FGGAGGFGTG---------GFGGGFGGSFSGKGGPGFP-------VCPAGG 182
                    FG   G G G         GFG G G  + G GGPGF        V  A  
Sbjct: 78  RFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGY-GFGGPGFGYRVGGVGVPAAPS 136

Query: 183 IQEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETK 242
           I  VT+N+SLLTPL++EIDP  Q+V+ +E+EQIK LNNKFASFIDKV+FLEQQNK+LETK
Sbjct: 137 ITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETK 196

Query: 243 WNLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYE 302
           W+ LQ+Q    S  NLEPLFE+Y++ LR+QL+ L +D+ RLQ+E   +QD +E FK KYE
Sbjct: 197 WSFLQEQKCIRS--NLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYE 254

Query: 303 EEINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVS 362
           EE+  R  AEN+FV LKKDVDAA++NK +LEA VD+L  EI+FLK LY  E+  +Q+H+S
Sbjct: 255 EEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHIS 314

Query: 363 DTSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNL 422
           +TSV++ MDN+R+L+LD IIAEV+AQYEE+A+RS+A+AEA YQTK +++Q++  QH DNL
Sbjct: 315 ETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNL 374

Query: 423 KNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAAL 482
           +N ++EI EL R+IQRL+AEIE+ K Q   L+ +VA+AEQ+GE  L DA  K  +LE AL
Sbjct: 375 RNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECAL 434

Query: 483 QQAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTS 542
           QQAK+++AR L EYQELM+ KL LDIEIATYR+LLEGEE R+   C+    +++   S+ 
Sbjct: 435 QQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRL---CEGVGPVNISVSSSR 491

Query: 543 TGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGSSSSKIIST 587
            G + G     +G  LS G       G  F GS S  ++S ++++
Sbjct: 492 GGLVCGPEPLVAGSTLSRG-------GVTFSGSSSVCATSGVLAS 529


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  440 bits (1132), Expect = e-123
 Identities = 265/486 (54%), Positives = 322/486 (66%), Gaps = 70/486 (14%)

Query: 83  RGGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGS 142
           RG   GFS  SA++ GG      S S S  A    S  FGS+SL  L G++S+++S A  
Sbjct: 10  RGERLGFSGCSAVLSGG----IGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAAR 65

Query: 143 RQGACFGGAGGFGTGGFGGGFGGSFSGKG-GPGFP-VCPAGGIQEVTINQSLLTPLHVEI 200
           R           G G  GG  G +F   G GP  P VCP GGI +VT+N+SLL PL+VE+
Sbjct: 66  R-----------GGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEM 114

Query: 201 DPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEP 260
           DPEIQ+VR +EREQIK LNNKFASFIDKV+FLEQQN+VLETKWNLLQQ       KNLEP
Sbjct: 115 DPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEP 174

Query: 261 LFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKK 320
           ++E Y+S L+KQL+ L  D  RL SEL+ MQD VED+K +YE EIN+RTAAEN+FVVLKK
Sbjct: 175 IYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKK 234

Query: 321 DVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDS 380
           DVDAAY+NKVEL+AKVDSL DEI F K LY+ E++Q+Q+H+SDTS+VLSMDNNR+LDLDS
Sbjct: 235 DVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDS 294

Query: 381 IIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISV---DQHGD-NLKNTKSEIAELNRMI 436
           IIAEVRAQYEEIA +SKAEAE LYQTK   L+ ++   +Q GD  LK+ ++++ EL    
Sbjct: 295 IIAEVRAQYEEIALKSKAEAETLYQTKCADLETAIADAEQRGDCALKDARAKLDEL---- 350

Query: 437 QRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREY 496
                                       E AL   H  + EL   L           REY
Sbjct: 351 ----------------------------EGAL---HQAKEELARML-----------REY 368

Query: 497 QELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGF 556
           QEL+S+KLALD+EIATYRKLLE EE RMSGE  ++VSISV+S   ST   +GG G   GF
Sbjct: 369 QELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVIS---STNAGAGGAGFSMGF 425

Query: 557 GLSSGF 562
           G SS +
Sbjct: 426 GASSSY 431


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  422 bits (1085), Expect = e-118
 Identities = 245/495 (49%), Positives = 332/495 (67%), Gaps = 29/495 (5%)

Query: 84  GGPRGFSCGSAIVGG-GKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGS 142
           G  R FS  SA+    G R   S+    G +      GFGSRSL NL G+    ++V G 
Sbjct: 13  GVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNL-GSCGPRIAVGGF 71

Query: 143 RQGACFGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDP 202
           R G+C            G  FG    G  GP  P C    I  V++N+SLLTPL++EIDP
Sbjct: 72  RAGSC------------GRSFGYRSGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDP 114

Query: 203 EIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLF 262
             Q V+ EE+EQIK LN++FA+FIDKV+FLEQQNK+LETKW   Q Q    S  NLEPLF
Sbjct: 115 NAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCES--NLEPLF 172

Query: 263 ETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDV 322
             Y+  LR++ + +  D GRL SEL  +Q+ +E +K KYEEE+  R  AEN+FVVLKKDV
Sbjct: 173 SGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDV 232

Query: 323 DAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSII 382
           D AYL K +LEA V++L +E +FL+ LY+ E+  +Q H+SDTSV++ MDN+R+L++D II
Sbjct: 233 DCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCII 292

Query: 383 AEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAE 442
           AE++AQY+++A RS+AEAE+ Y++K ++++ +V +HG+ L+ TK EI ELNRMIQRL AE
Sbjct: 293 AEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE 352

Query: 443 IENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSV 502
           IEN K Q   L+ +VA+AEQ+GE AL DA  K  ELE ALQ+AK+++A +L+EYQE+M+ 
Sbjct: 353 IENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNS 412

Query: 503 KLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLSSGF 562
           KL LDIEIATYR+LLEGEE+R+   C+   S++V   S+S GG+S G   G  +  + G 
Sbjct: 413 KLGLDIEIATYRRLLEGEEHRL---CEGVGSVNVCV-SSSRGGVSCG---GLSYSTTPGR 465

Query: 563 GSGSGSGFGFGGSVS 577
              SG     GGS++
Sbjct: 466 QITSGPS-AIGGSIT 479


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  404 bits (1039), Expect = e-113
 Identities = 228/467 (48%), Positives = 309/467 (66%), Gaps = 35/467 (7%)

Query: 85  GPRGFSCGSAIVGGGKRGAFSSVSMSG-GAGRCSSGGFGSRSLYNLRGNKSISMSVAGSR 143
           G R FSC SA      R   ++    G    R  +GGFGS S+                 
Sbjct: 8   GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSV----------------- 50

Query: 144 QGACFGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDPE 203
                   GGF  G  G  FG    G  GP  P C    I  V++N+SLLTPL++EIDP 
Sbjct: 51  -------CGGFRAGSCGRSFGYRSGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPN 98

Query: 204 IQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFE 263
            Q V+ EE+EQIK LN++FA+FIDKV+FLEQQNK+LETK    Q +    S  NLEPLFE
Sbjct: 99  AQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFE 156

Query: 264 TYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVD 323
            Y+  LR++ + +  D GRL SEL  +Q+ +E +K KYEEE++ R  AEN+FV LKKDVD
Sbjct: 157 GYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVD 216

Query: 324 AAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIA 383
            AYL K +LEA V++L  EI+FL+ LY+ E+  +Q+H+SDTSVV+ +DN+R+L++D IIA
Sbjct: 217 CAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIA 276

Query: 384 EVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEI 443
           E++AQY++I  RS+AEAE+ Y++K ++++ +V +HG+ L+ TK EI ELNRMIQRL AE+
Sbjct: 277 EIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEV 336

Query: 444 ENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVK 503
           EN K Q   L+ +VA +EQ+GE AL DA  K  ELE ALQ+AK+++A ++REYQE+M+ K
Sbjct: 337 ENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSK 396

Query: 504 LALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGL 550
           L LDIEIATYR+LLEGEE R+   C+   S++V   S+  G + G L
Sbjct: 397 LGLDIEIATYRRLLEGEEQRL---CEGVGSVNVCVSSSRGGVVCGDL 440


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  404 bits (1039), Expect = e-113
 Identities = 228/467 (48%), Positives = 309/467 (66%), Gaps = 35/467 (7%)

Query: 85  GPRGFSCGSAIVGGGKRGAFSSVSMSG-GAGRCSSGGFGSRSLYNLRGNKSISMSVAGSR 143
           G R FSC SA      R   ++    G    R  +GGFGS S+                 
Sbjct: 8   GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSV----------------- 50

Query: 144 QGACFGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDPE 203
                   GGF  G  G  FG    G  GP  P C    I  V++N+SLLTPL++EIDP 
Sbjct: 51  -------CGGFRAGSCGRSFGYRSGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPN 98

Query: 204 IQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFE 263
            Q V+ EE+EQIK LN++FA+FIDKV+FLEQQNK+LETK    Q +    S  NLEPLFE
Sbjct: 99  AQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFE 156

Query: 264 TYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVD 323
            Y+  LR++ + +  D GRL SEL  +Q+ +E +K KYEEE++ R  AEN+FV LKKDVD
Sbjct: 157 GYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVD 216

Query: 324 AAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIA 383
            AYL K +LEA V++L  EI+FL+ LY+ E+  +Q+H+SDTSVV+ +DN+R+L++D IIA
Sbjct: 217 CAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIA 276

Query: 384 EVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEI 443
           E++AQY++I  RS+AEAE+ Y++K ++++ +V +HG+ L+ TK EI ELNRMIQRL AE+
Sbjct: 277 EIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEV 336

Query: 444 ENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVK 503
           EN K Q   L+ +VA +EQ+GE AL DA  K  ELE ALQ+AK+++A ++REYQE+M+ K
Sbjct: 337 ENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSK 396

Query: 504 LALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGL 550
           L LDIEIATYR+LLEGEE R+   C+   S++V   S+  G + G L
Sbjct: 397 LGLDIEIATYRRLLEGEEQRL---CEGVGSVNVCVSSSRGGVVCGDL 440


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  404 bits (1039), Expect = e-113
 Identities = 228/467 (48%), Positives = 309/467 (66%), Gaps = 35/467 (7%)

Query: 85  GPRGFSCGSAIVGGGKRGAFSSVSMSG-GAGRCSSGGFGSRSLYNLRGNKSISMSVAGSR 143
           G R FSC SA      R   ++    G    R  +GGFGS S+                 
Sbjct: 8   GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSV----------------- 50

Query: 144 QGACFGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDPE 203
                   GGF  G  G  FG    G  GP  P C    I  V++N+SLLTPL++EIDP 
Sbjct: 51  -------CGGFRAGSCGRSFGYRSGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPN 98

Query: 204 IQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFE 263
            Q V+ EE+EQIK LN++FA+FIDKV+FLEQQNK+LETK    Q +    S  NLEPLFE
Sbjct: 99  AQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFE 156

Query: 264 TYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVD 323
            Y+  LR++ + +  D GRL SEL  +Q+ +E +K KYEEE++ R  AEN+FV LKKDVD
Sbjct: 157 GYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVD 216

Query: 324 AAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIA 383
            AYL K +LEA V++L  EI+FL+ LY+ E+  +Q+H+SDTSVV+ +DN+R+L++D IIA
Sbjct: 217 CAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIA 276

Query: 384 EVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEI 443
           E++AQY++I  RS+AEAE+ Y++K ++++ +V +HG+ L+ TK EI ELNRMIQRL AE+
Sbjct: 277 EIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEV 336

Query: 444 ENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVK 503
           EN K Q   L+ +VA +EQ+GE AL DA  K  ELE ALQ+AK+++A ++REYQE+M+ K
Sbjct: 337 ENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSK 396

Query: 504 LALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGL 550
           L LDIEIATYR+LLEGEE R+   C+   S++V   S+  G + G L
Sbjct: 397 LGLDIEIATYRRLLEGEEQRL---CEGVGSVNVCVSSSRGGVVCGDL 440


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  404 bits (1039), Expect = e-113
 Identities = 228/467 (48%), Positives = 309/467 (66%), Gaps = 35/467 (7%)

Query: 85  GPRGFSCGSAIVGGGKRGAFSSVSMSG-GAGRCSSGGFGSRSLYNLRGNKSISMSVAGSR 143
           G R FSC SA      R   ++    G    R  +GGFGS S+                 
Sbjct: 8   GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSV----------------- 50

Query: 144 QGACFGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDPE 203
                   GGF  G  G  FG    G  GP  P C    I  V++N+SLLTPL++EIDP 
Sbjct: 51  -------CGGFRAGSCGRSFGYRSGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPN 98

Query: 204 IQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFE 263
            Q V+ EE+EQIK LN++FA+FIDKV+FLEQQNK+LETK    Q +    S  NLEPLFE
Sbjct: 99  AQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFE 156

Query: 264 TYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVD 323
            Y+  LR++ + +  D GRL SEL  +Q+ +E +K KYEEE++ R  AEN+FV LKKDVD
Sbjct: 157 GYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVD 216

Query: 324 AAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIA 383
            AYL K +LEA V++L  EI+FL+ LY+ E+  +Q+H+SDTSVV+ +DN+R+L++D IIA
Sbjct: 217 CAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIA 276

Query: 384 EVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEI 443
           E++AQY++I  RS+AEAE+ Y++K ++++ +V +HG+ L+ TK EI ELNRMIQRL AE+
Sbjct: 277 EIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEV 336

Query: 444 ENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVK 503
           EN K Q   L+ +VA +EQ+GE AL DA  K  ELE ALQ+AK+++A ++REYQE+M+ K
Sbjct: 337 ENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSK 396

Query: 504 LALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGL 550
           L LDIEIATYR+LLEGEE R+   C+   S++V   S+  G + G L
Sbjct: 397 LGLDIEIATYRRLLEGEEQRL---CEGVGSVNVCVSSSRGGVVCGDL 440


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  402 bits (1034), Expect = e-112
 Identities = 228/462 (49%), Positives = 312/462 (67%), Gaps = 24/462 (5%)

Query: 90  SCGSAIVGGGKRGAFSSVSMSGGA-GRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGACF 148
           +CGS    GG+  AFS +S  G   GRC       R +   RG     ++        C 
Sbjct: 2   TCGSGF--GGR--AFSCISACGPRPGRCCITAAPYRGISCYRG-----LTGGFGSHSVC- 51

Query: 149 GGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDPEIQKVR 208
              GGF  G  G  FG    G  GP  P C    I  V++N+SLLTPL++EIDP  Q V+
Sbjct: 52  ---GGFRAGSCGRSFGYRSGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVK 103

Query: 209 TEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFETYLSV 268
            EE+EQIK LN++FA+FIDKV+FLEQQNK+LETK    Q +    S  NLEPLFE Y+  
Sbjct: 104 QEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFEGYIET 161

Query: 269 LRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYLN 328
           LR++ + +  D GRL SEL  +Q+ +E +K KYEEE++ R  AEN+FV LKKDVD AYL 
Sbjct: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221

Query: 329 KVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRAQ 388
           K +LEA V++L  EI+FL+ LY+ E+  +Q+H+SDTSVV+ +DN+R+L++D IIAE++AQ
Sbjct: 222 KSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281

Query: 389 YEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIKK 448
           Y++I  RS+AEAE+ Y++K ++++ +V +HG+ L+ TK EI ELNRMIQRL AE+EN K 
Sbjct: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341

Query: 449 QCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVKLALDI 508
           Q   L+ +VA +EQ+GE AL DA  K  ELE ALQ+AK+++A ++REYQE+M+ KL LDI
Sbjct: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401

Query: 509 EIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGL 550
           EIATYR+LLEGEE R+   C+   +++V   S+  G + G L
Sbjct: 402 EIATYRRLLEGEEQRL---CEGIGAVNVCVSSSRGGVVCGDL 440


>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  401 bits (1030), Expect = e-111
 Identities = 227/463 (49%), Positives = 310/463 (66%), Gaps = 21/463 (4%)

Query: 90  SCGSAIVGGGKR-GAFSSVSMSGGA-GRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGAC 147
           +CG   +G G R G FS VS  G    RC       R +   RG     ++        C
Sbjct: 2   TCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRG-----LTGGFGSHSVC 56

Query: 148 FGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDPEIQKV 207
               GGF  G  G  FG    G  GP  P C    I  V++N+SLLTPL++EIDP  Q V
Sbjct: 57  ----GGFRAGSCGRSFGYRSGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCV 107

Query: 208 RTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFETYLS 267
           + EE+EQIK LN++FA+FIDKV+FLEQQNK+LETK    Q +    S  NLEPLF  Y+ 
Sbjct: 108 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFAGYIE 165

Query: 268 VLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYL 327
            LR++ + +  D GRL SEL  +Q+ +E +K KYEEE+  R  AEN+FV LKKDVD AYL
Sbjct: 166 TLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYL 225

Query: 328 NKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRA 387
            K +LEA V++L  EI+FL+ LY+ E+  +Q+H+SDTSVV+ +DN+R+L++D I+AE++A
Sbjct: 226 RKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKA 285

Query: 388 QYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIK 447
           QY++IA RS+AEAE+ Y++K ++++ +V +HG+ L+ TK EI ELNRMIQRL AE+EN K
Sbjct: 286 QYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAK 345

Query: 448 KQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVKLALD 507
            Q   L+ +VA +EQ+GE AL DA  K  ELE ALQ+AK+++A ++REYQE+M+ KL LD
Sbjct: 346 CQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLD 405

Query: 508 IEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGL 550
           IEIATYR+LLEGEE R+   C+   +++V   S+  G + G L
Sbjct: 406 IEIATYRRLLEGEEQRL---CEGVEAVNVCVSSSRGGVVCGDL 445


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  400 bits (1029), Expect = e-111
 Identities = 235/500 (47%), Positives = 322/500 (64%), Gaps = 42/500 (8%)

Query: 115 RCSSGGFGSRSLYNLRGNKSISMSVAGSRQGA--------CFGGAG----GFGTGGFGGG 162
           RC S  F S S    R     ++S    R G         C G       GFG       
Sbjct: 11  RCGSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCNVGFGRPRVASR 70

Query: 163 FGGSFSGKGGPGFPVC-PAGGIQEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNK 221
            GG+  G G      C P+  I  VTIN+SLL PL +EIDP +Q+V+ +E+EQIK LNN+
Sbjct: 71  CGGTLPGFGYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKCLNNR 130

Query: 222 FASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKG 281
           FASFI+KV+FLEQ+NK+LETKWN +QQQ    +  N+EP+FE Y+S LR+QLD +  D+ 
Sbjct: 131 FASFINKVRFLEQKNKLLETKWNFMQQQRCCQT--NIEPIFEGYISALRRQLDCVSGDRV 188

Query: 282 RLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLND 341
           RL+SEL ++Q ++E +K KYEEE++ R   EN+FV LKKDVD A+L K +LE   ++L  
Sbjct: 189 RLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEALVQ 248

Query: 342 EINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAE 401
           EI+FLK LY+ E+  +Q+ +S+TSV++ MDN+R LD+D IIAE++AQY++IA RSKAEAE
Sbjct: 249 EIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAEAE 308

Query: 402 ALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAE 461
           A YQ + ++L+++   H DNL+N K+EI E+N++IQRL+ E EN+K Q   L+ ++A+AE
Sbjct: 309 AWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAEAE 368

Query: 462 QRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEE 521
           Q+GE AL DA  K   LE ALQ+AK+++A +L+EYQE+M+ KL LDIEIATYR+LLEGEE
Sbjct: 369 QQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEE 428

Query: 522 YRMSGECQSAVSISVVSGS--------------TSTGGI--SGG---LGSGSGFG----- 557
           +R+  E    V+ISV S                 STG +  +GG   +G+G  +      
Sbjct: 429 HRLC-EGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGELYVPCEPQ 487

Query: 558 --LSSGFGSGSGSGFGFGGS 575
             LS G G  S    G GGS
Sbjct: 488 GLLSCGSGRKSSMTLGAGGS 507


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,734,588
Number of Sequences: 37866
Number of extensions: 1076400
Number of successful extensions: 18651
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 369
Number of HSP's successfully gapped in prelim test: 737
Number of HSP's that attempted gapping in prelim test: 6983
Number of HSP's gapped (non-prelim): 6469
length of query: 594
length of database: 18,247,518
effective HSP length: 108
effective length of query: 486
effective length of database: 14,157,990
effective search space: 6880783140
effective search space used: 6880783140
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.