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Search of human proteins with 14318422
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14318422 keratin 86 [Homo sapiens]
(486 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap... 974 0.0
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap... 974 0.0
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap... 974 0.0
gi|14318422 keratin 86 [Homo sapiens] 974 0.0
gi|169790853 keratin, hair, basic, 1 [Homo sapiens] 897 0.0
gi|169790841 keratin 83 [Homo sapiens] 872 0.0
gi|4504935 keratin 85 [Homo sapiens] 789 0.0
gi|15431316 keratin, hair, basic, 4 [Homo sapiens] 544 e-155
gi|27477127 keratin 82 [Homo sapiens] 533 e-151
gi|119395754 keratin 5 [Homo sapiens] 436 e-122
gi|5031839 keratin 6A [Homo sapiens] 427 e-119
gi|155969697 keratin 6C [Homo sapiens] 425 e-119
gi|153791158 keratin 75 [Homo sapiens] 424 e-118
gi|119703753 keratin 6B [Homo sapiens] 423 e-118
gi|4504919 keratin 8 [Homo sapiens] 415 e-116
gi|109148552 keratin 3 [Homo sapiens] 408 e-114
gi|67782365 keratin 7 [Homo sapiens] 407 e-113
gi|109255249 keratin 4 [Homo sapiens] 404 e-113
gi|15618995 keratin 71 [Homo sapiens] 402 e-112
gi|28173564 keratin 73 [Homo sapiens] 396 e-110
gi|119395750 keratin 1 [Homo sapiens] 394 e-109
gi|153791670 keratin 76 [Homo sapiens] 392 e-109
gi|28372503 keratin 72 isoform 1 [Homo sapiens] 391 e-109
gi|226246663 keratin 72 isoform 1 [Homo sapiens] 391 e-109
gi|32567786 keratin 6L [Homo sapiens] 389 e-108
gi|47132620 keratin 2 [Homo sapiens] 381 e-106
gi|148612803 keratin 6 irs4 [Homo sapiens] 379 e-105
gi|194018511 keratin 77 [Homo sapiens] 352 3e-97
gi|89357932 keratin 5b [Homo sapiens] 346 3e-95
gi|226246665 keratin 72 isoform 2 [Homo sapiens] 335 5e-92
>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 486
Score = 974 bits (2518), Expect = 0.0
Identities = 486/486 (100%), Positives = 486/486 (100%)
Query: 1 MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG
Sbjct: 1 MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
Query: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF
Sbjct: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
Query: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
Query: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK
Sbjct: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
Query: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG 480
VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG
Sbjct: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG 480
Query: 481 GSCKRC 486
GSCKRC
Sbjct: 481 GSCKRC 486
>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 486
Score = 974 bits (2518), Expect = 0.0
Identities = 486/486 (100%), Positives = 486/486 (100%)
Query: 1 MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG
Sbjct: 1 MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
Query: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF
Sbjct: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
Query: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
Query: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK
Sbjct: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
Query: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG 480
VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG
Sbjct: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG 480
Query: 481 GSCKRC 486
GSCKRC
Sbjct: 481 GSCKRC 486
>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
sapiens]
Length = 486
Score = 974 bits (2518), Expect = 0.0
Identities = 486/486 (100%), Positives = 486/486 (100%)
Query: 1 MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG
Sbjct: 1 MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
Query: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF
Sbjct: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
Query: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
Query: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK
Sbjct: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
Query: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG 480
VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG
Sbjct: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG 480
Query: 481 GSCKRC 486
GSCKRC
Sbjct: 481 GSCKRC 486
>gi|14318422 keratin 86 [Homo sapiens]
Length = 486
Score = 974 bits (2518), Expect = 0.0
Identities = 486/486 (100%), Positives = 486/486 (100%)
Query: 1 MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG
Sbjct: 1 MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
Query: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF
Sbjct: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
Query: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
Query: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK
Sbjct: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
Query: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG 480
VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG
Sbjct: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG 480
Query: 481 GSCKRC 486
GSCKRC
Sbjct: 481 GSCKRC 486
>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
Length = 505
Score = 897 bits (2319), Expect = 0.0
Identities = 457/507 (90%), Positives = 465/507 (91%), Gaps = 23/507 (4%)
Query: 1 MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
MTCGS GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG
Sbjct: 1 MTCGSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
Query: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF
Sbjct: 61 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
Query: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
Query: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
RLYEEEI +LQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK
Sbjct: 241 RLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
Query: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAP-------- 472
+G+VNVCVSSSRGGVVCGDLC S + PV + V S P N NV V +T CAP
Sbjct: 421 IGAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNVAV-STGLCAPCGQLNTTC 478
Query: 473 -------------SARVGVCGGSCKRC 486
S VG CG SC++C
Sbjct: 479 GGGSCGVGSCGISSLGVGSCGSSCRKC 505
>gi|169790841 keratin 83 [Homo sapiens]
Length = 493
Score = 872 bits (2253), Expect = 0.0
Identities = 445/490 (90%), Positives = 456/490 (93%), Gaps = 9/490 (1%)
Query: 1 MTCGSY---CGGRA--FSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55
MTCG CG R FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR
Sbjct: 1 MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60
Query: 56 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115
AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS
Sbjct: 61 AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120
Query: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175
RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR
Sbjct: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180
Query: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235
LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE
Sbjct: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240
Query: 236 IDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295
IDFLRRLYEEEIR+LQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES
Sbjct: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300
Query: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355
WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ
Sbjct: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360
Query: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415
QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ
Sbjct: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420
Query: 416 RLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR 475
RLCEGV +VNVCVSSSRGGVVCGDLC S + PV + V S P N N+VV +T C P +
Sbjct: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNLVV-STGLCKPCGQ 478
Query: 476 VGVC--GGSC 483
+ GGSC
Sbjct: 479 LNTTCGGGSC 488
>gi|4504935 keratin 85 [Homo sapiens]
Length = 507
Score = 789 bits (2038), Expect = 0.0
Identities = 408/492 (82%), Positives = 436/492 (88%), Gaps = 24/492 (4%)
Query: 1 MTCGSY-----CG-GRAFSCISACGPRPG-RCCITAAPYRGISCYRGLTGGFGSHSVC-- 51
M+C SY CG R FS SA P+ G RCCI+AAPYRG+SCYRGLTG FGS S+C
Sbjct: 1 MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTG-FGSRSLCNL 59
Query: 52 ---------GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 102
GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV
Sbjct: 60 GSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 119
Query: 103 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETL 162
KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETK QFYQN+ CC+SNLEPLF GYIETL
Sbjct: 120 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETL 179
Query: 163 RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRK 222
RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEV+LRATAENEFV LKKDVDCAYLRK
Sbjct: 180 RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRK 239
Query: 223 SDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQY 282
SDLEANVEAL++E FLRRLYEEEIRVLQ+HISDTSV+VK+DNSRDLNMDCIIAEIKAQY
Sbjct: 240 SDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQY 299
Query: 283 DDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQ 342
DD+ +RSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE+ENAKCQ
Sbjct: 300 DDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQ 359
Query: 343 NSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIE 402
+KLEAAVA++EQQGEAALSDARCKLAELEGALQKAKQDMACL++EYQEVMNSKLGLDIE
Sbjct: 360 RAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIE 419
Query: 403 IATYRRLLEGEEQRLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPS--NS 460
IATYRRLLEGEE RLCEGVGSVNVCVSSSRGGV CG L STT +++S PS
Sbjct: 420 IATYRRLLEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTP---GRQITSGPSAIGG 476
Query: 461 NVVVGTTNACAP 472
++ V ++CAP
Sbjct: 477 SITVVAPDSCAP 488
>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
Length = 600
Score = 544 bits (1402), Expect = e-155
Identities = 295/477 (61%), Positives = 362/477 (75%), Gaps = 17/477 (3%)
Query: 15 ISACGPRPGRCCIT--AAPYRGISCYRGLTGGFGSHSVCG-GFRAGSC------GRSFGY 65
I+A G RP C + A G RG+ G + S G GF AGS G FGY
Sbjct: 65 IAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGY 124
Query: 66 RSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVR 125
R GGV P+ P IT V+VN+SLLTPLNLEIDPNAQ VK++EKEQIK+LN++FA+FIDKVR
Sbjct: 125 RVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVR 184
Query: 126 FLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQE 185
FLEQQNKLLETK F Q ++C +SNLEPLFE YI LRR+ E + +D RL +E NH+Q+
Sbjct: 185 FLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQD 244
Query: 186 VLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 245
VLEG+KKKYEEEV RA AENEFVALKKDVD A++ KSDLEANV+ L QEIDFL+ LY E
Sbjct: 245 VLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYME 304
Query: 246 EIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMK 305
EI++LQSHIS+TSV+VK+DNSRDLN+D IIAE+KAQY+++ RSRA+AE+WY++K EEM+
Sbjct: 305 EIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQ 364
Query: 306 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 365
T +H + LR + EINEL R+IQRL AE+E+AK Q +KLEAAVA++EQQGEA LSDA+
Sbjct: 365 VTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAK 424
Query: 366 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGSVN 425
CKLA+LE ALQ+AKQDMA + EYQE+MN+KLGLDIEIATYRRLLEGEE RLCEGVG VN
Sbjct: 425 CKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVN 484
Query: 426 VCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCGGS 482
+ VSSSRGG+VCG P+V+ S++ G+++ CA S + CG S
Sbjct: 485 ISVSSSRGGLVCG------PEPLVAG--STLSRGGVTFSGSSSVCATSGVLASCGPS 533
>gi|27477127 keratin 82 [Homo sapiens]
Length = 513
Score = 533 bits (1373), Expect = e-151
Identities = 299/495 (60%), Positives = 358/495 (72%), Gaps = 20/495 (4%)
Query: 4 GSYCGGRAFSCISACGPRP-GRCCITAAPYRGISCYRGLT--GGFGSHSVCG-GFR---- 55
GS CG ++FS SA PR ++ P R RGL G GS S+C GF
Sbjct: 9 GSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRP-GGGRGLRALGCLGSRSLCNVGFGRPRV 67
Query: 56 AGSCGRS---FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKS 112
A CG + FGYR G CGPS CIT V++NESLL PL LEIDP Q VK++EKEQIK
Sbjct: 68 ASRCGGTLPGFGYRLGATCGPSA-CITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKC 126
Query: 113 LNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEAD 172
LN+RFA+FI+KVRFLEQ+NKLLETK F Q + CCQ+N+EP+FEGYI LRR+ +CV D
Sbjct: 127 LNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCVSGD 186
Query: 173 SGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEAL 232
RL SEL +Q LEGYKKKYEEE+SLR ENEFVALKKDVD A+L K+DLE N EAL
Sbjct: 187 RVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEAL 246
Query: 233 IQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAE 292
+QEIDFL+ LYEEEI +LQS IS+TSV+VK+DNSR+L++D IIAEIKAQYDDI +RS+AE
Sbjct: 247 VQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAE 306
Query: 293 AESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQ 352
AE+WY+ + EE++ T H + LR K EI E+N++IQRL E EN K Q KLE A+A+
Sbjct: 307 AEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAE 366
Query: 353 SEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEG 412
+EQQGEAAL+DA+CKLA LE ALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRLLEG
Sbjct: 367 AEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEG 426
Query: 413 EEQRLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNV-VVGTTNACA 471
EE RLCEG+G VN+ VSSS+G + ST PV+ST V + SN +VGT
Sbjct: 427 EEHRLCEGIGPVNISVSSSKGAFLYEPCGVST--PVLSTGV--LRSNGGCSIVGTGELYV 482
Query: 472 PSARVGV--CGGSCK 484
P G+ CG K
Sbjct: 483 PCEPQGLLSCGSGRK 497
>gi|119395754 keratin 5 [Homo sapiens]
Length = 590
Score = 436 bits (1122), Expect = e-122
Identities = 246/472 (52%), Positives = 324/472 (68%), Gaps = 29/472 (6%)
Query: 40 GLTGGFGSHSVCGGFRAGSCGRSFGYR-SGGVCGPS-PPC----ITTVSVNESLLTPLNL 93
G GG GS GG G G G GG GP P C I V+VN+SLLTPLNL
Sbjct: 96 GFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 155
Query: 94 EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 151
+IDP+ Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK Q + + + NL
Sbjct: 156 QIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 215
Query: 152 EPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVAL 211
EPLFE YI LRR+ + + + GRL SEL ++Q+++E +K KYE+E++ R TAENEFV L
Sbjct: 216 EPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVML 275
Query: 212 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNM 271
KKDVD AY+ K +LEA V+AL+ EI+F++ ++ E+ +Q+H+SDTSVV+ +DN+R+L++
Sbjct: 276 KKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDL 335
Query: 272 DCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 331
D IIAE+KAQY++I RSR EAESWY++K EE++ T RHG+ LR TK EI+E+NRMIQR
Sbjct: 336 DSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQR 395
Query: 332 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 391
L AE++N K Q + L+ A+A +EQ+GE AL DAR KLAELE ALQKAKQDMA L+REYQE
Sbjct: 396 LRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQE 455
Query: 392 VMNSKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSSR------------------ 432
+MN+KL LD+EIATYR+LLEGEE RL EGVG VN+ V +S
Sbjct: 456 LMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGG 515
Query: 433 -GGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR-VGVCGGS 482
GG + G L ++ S+ V + VG + A S R +GV GS
Sbjct: 516 LGGGLGGGLAGGSSGSYYSSSSGGVGLGGGLSVGGSGFSASSGRGLGVGFGS 567
>gi|5031839 keratin 6A [Homo sapiens]
Length = 564
Score = 427 bits (1097), Expect = e-119
Identities = 237/451 (52%), Positives = 312/451 (69%), Gaps = 30/451 (6%)
Query: 4 GSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSF 63
G CGG F S G + G SC ++GG+GS + G + G G F
Sbjct: 48 GGACGGAGFGSRSLYGLGGSK----RISIGGGSC--AISGGYGSRAG-GSYGFGGAGSGF 100
Query: 64 GYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVK 103
G+ +GG GP P C I V+VN+SLLTPLNL+IDP Q V+
Sbjct: 101 GFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVR 160
Query: 104 QEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNLEPLFEGYIET 161
EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK Q + + + NLEPLFE YI
Sbjct: 161 AEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINN 220
Query: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221
LRR+ + + + GRL SEL +Q+++E +K KYE+E++ R AENEFV LKKDVD AY+
Sbjct: 221 LRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMN 280
Query: 222 KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281
K +L+A + L EI+FLR LY+ E+ +Q+HISDTSVV+ +DN+R+L++D IIAE+KAQ
Sbjct: 281 KVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQ 340
Query: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341
Y++I RSRAEAESWY++K EE++ T RHG+ LR TK+EI E+NRMIQRL +E+++ K
Sbjct: 341 YEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKK 400
Query: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401
Q + L+AA+A +EQ+GE AL DA+ KL LE ALQKAKQD+A L++EYQE+MN KL LD+
Sbjct: 401 QCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDV 460
Query: 402 EIATYRRLLEGEEQRL-CEGVGSVNVCVSSS 431
EIATYR+LLEGEE RL EGVG VN+ V S
Sbjct: 461 EIATYRKLLEGEECRLNGEGVGQVNISVVQS 491
>gi|155969697 keratin 6C [Homo sapiens]
Length = 564
Score = 425 bits (1092), Expect = e-119
Identities = 237/451 (52%), Positives = 312/451 (69%), Gaps = 30/451 (6%)
Query: 4 GSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSF 63
G CGG F S G + G SC ++GG+GS + G + G G F
Sbjct: 48 GGACGGAGFGSRSLYGLGGSK----RISIGGGSC--AISGGYGSRAG-GSYGFGGAGSGF 100
Query: 64 GYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVK 103
G+ +GG GP P C I V+VN+SLLTPLNL+IDP Q V+
Sbjct: 101 GFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVR 160
Query: 104 QEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNLEPLFEGYIET 161
EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK Q + + + NLEPLFE YI
Sbjct: 161 AEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINN 220
Query: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221
LRR+ + + + GRL SEL ++Q+++E K KYE+E++ R AENEFV LKKDVD AY+
Sbjct: 221 LRRQLDSIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMN 280
Query: 222 KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281
K +L+A + L EI+FLR LY+ E+ +Q+HISDTSVV+ +DN+R+L++D IIAE+KAQ
Sbjct: 281 KVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQ 340
Query: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341
Y++I RSRAEAESWY++K EE++ T RHG+ LR TK+EI E+NRMIQRL +E+++ K
Sbjct: 341 YEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKK 400
Query: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401
Q + L+AA+A +EQ+GE AL DA+ KL LE ALQKAKQD+A L++EYQE+MN KL LD+
Sbjct: 401 QCASLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDV 460
Query: 402 EIATYRRLLEGEEQRL-CEGVGSVNVCVSSS 431
EIATYR+LLEGEE RL EGVG VNV V S
Sbjct: 461 EIATYRKLLEGEECRLNGEGVGQVNVSVVQS 491
>gi|153791158 keratin 75 [Homo sapiens]
Length = 551
Score = 424 bits (1089), Expect = e-118
Identities = 241/463 (52%), Positives = 316/463 (68%), Gaps = 41/463 (8%)
Query: 10 RAFSCISACGPRPGRCCIT-------AAPYRGISCYRGLTGGFGSHSV------------ 50
R FS SA P GR + AA G+ FGS S+
Sbjct: 15 RGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLYNLGGAKRVSIN 74
Query: 51 -CGGF-RAGSCGRS---------FGYRSG---GVCGPS-PPC----ITTVSVNESLLTPL 91
CG R+G GR+ FGY G G GPS P C I V+VN+SLLTPL
Sbjct: 75 GCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEVTVNQSLLTPL 134
Query: 92 NLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQS 149
+L+IDP Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK Q + +
Sbjct: 135 HLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQ 194
Query: 150 NLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFV 209
NLEPLF+ Y LRR+ E + + GRL +EL ++Q+V+E +K +YE+E++ R AENEFV
Sbjct: 195 NLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFV 254
Query: 210 ALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDL 269
ALKKDVD AY+ K +LEA V++L +EI+F+ +++ E+ LQ+ + DTSVV+ +DN+R+L
Sbjct: 255 ALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNL 314
Query: 270 NMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMI 329
++D IIAE+KAQY+DI RSRAEAESWY++K EE++ T RHG+ LR TK+EI+E+NRMI
Sbjct: 315 DLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMI 374
Query: 330 QRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREY 389
QRL AE+++ K Q S L+ A+A +EQ+GE AL DAR KL +LE ALQKAKQDMA L+REY
Sbjct: 375 QRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREY 434
Query: 390 QEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431
QE+MN KL LD+EIATYR+LLEGEE RL EGV VN+ V +S
Sbjct: 435 QELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTS 477
>gi|119703753 keratin 6B [Homo sapiens]
Length = 564
Score = 423 bits (1088), Expect = e-118
Identities = 236/451 (52%), Positives = 312/451 (69%), Gaps = 30/451 (6%)
Query: 4 GSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSF 63
G CGG F S G + G SC ++GG+GS + G + G G F
Sbjct: 48 GGACGGAGFGSRSLYGLGGSK----RISIGGGSC--AISGGYGSRAG-GSYGFGGAGSGF 100
Query: 64 GYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVK 103
G+ +GG GP P C I V+VN+SLLTPLNL+IDP Q V+
Sbjct: 101 GFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVR 160
Query: 104 QEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNLEPLFEGYIET 161
EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK Q + + + NLEPLFE YI
Sbjct: 161 AEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINN 220
Query: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221
LRR+ + + + GRL SEL ++Q+++E K KYE+E++ R AENEFV LKKDVD AY+
Sbjct: 221 LRRQLDNIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMN 280
Query: 222 KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281
K +L+A + L EI+FLR LY+ E+ +Q+HISDTSVV+ +DN+R+L++D IIAE+KAQ
Sbjct: 281 KVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQ 340
Query: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341
Y++I RSRAEAESWY++K EE++ T RHG+ LR TK+EI E+NRMIQRL +E+++ K
Sbjct: 341 YEEIAQRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKK 400
Query: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401
Q + L+AA+A +EQ+GE AL DA+ KL LE ALQKAKQD+A L++EYQE+MN KL LD+
Sbjct: 401 QCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDV 460
Query: 402 EIATYRRLLEGEEQRL-CEGVGSVNVCVSSS 431
EIATYR+LLEGEE RL EGVG VN+ V S
Sbjct: 461 EIATYRKLLEGEECRLNGEGVGQVNISVVQS 491
>gi|4504919 keratin 8 [Homo sapiens]
Length = 483
Score = 415 bits (1067), Expect = e-116
Identities = 227/430 (52%), Positives = 299/430 (69%), Gaps = 25/430 (5%)
Query: 5 SYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRG-LTGGFGSHSVCGGFRAGSCGRSF 63
S G RAFS S R ++ G S +RG L GG+G S GG
Sbjct: 13 STSGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGG---------- 62
Query: 64 GYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDK 123
IT V+VN+SLL+PL LE+DPN Q V+ +EKEQIK+LN++FA+FIDK
Sbjct: 63 --------------ITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDK 108
Query: 124 VRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHV 183
VRFLEQQNK+LETK Q ++ +SN++ +FE YI LRR+ E + + +L +EL ++
Sbjct: 109 VRFLEQQNKMLETKWSLLQQQKTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNM 168
Query: 184 QEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLY 243
Q ++E +K KYE+E++ R ENEFV +KKDVD AY+ K +LE+ +E L EI+FLR+LY
Sbjct: 169 QGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLY 228
Query: 244 EEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEE 303
EEEIR LQS ISDTSVV+ +DNSR L+MD IIAE+KAQY+DI RSRAEAES Y+ K EE
Sbjct: 229 EEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEE 288
Query: 304 MKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSD 363
+++ +HG+ LRRTK EI+E+NR I RL AE+E K Q + LEAA+A +EQ+GE A+ D
Sbjct: 289 LQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKD 348
Query: 364 ARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGS 423
A KL+ELE ALQ+AKQDMA +REYQE+MN KL LDIEIATYR+LLEGEE RL G+ +
Sbjct: 349 ANAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQN 408
Query: 424 VNVCVSSSRG 433
+++ ++ G
Sbjct: 409 MSIHTKTTSG 418
>gi|109148552 keratin 3 [Homo sapiens]
Length = 628
Score = 408 bits (1049), Expect = e-114
Identities = 233/456 (51%), Positives = 306/456 (67%), Gaps = 31/456 (6%)
Query: 4 GSYCGGRAFSCISACGPRPGRCCITAAPYRG-ISCYRGLTGGFGSHSVCGGFRAGSCGRS 62
G + GGR+ SC A G G + G RG+ GGFG GG AG G +
Sbjct: 78 GGFGGGRS-SCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGG--AGGFGGA 134
Query: 63 FGY-------RSGGVCGPS-------------PPCITTVSVNESLLTPLNLEIDPNAQCV 102
G+ SGG GP P I V++N+SLL PLN+EIDP V
Sbjct: 135 GGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQPLNVEIDPQIGQV 194
Query: 103 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ----SNLEPLFEGY 158
K +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK Q + +NLEPLFE +
Sbjct: 195 KAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLFENH 254
Query: 159 IETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCA 218
I LR + + + GRL SEL ++++++E +KKKYE+E++ R AENEFV LKKDVD A
Sbjct: 255 INYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDSA 314
Query: 219 YLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEI 278
Y+ K +L+A V+ALI EIDFLR LY+ E+ +QSHISDTSVV+ +DN+R L++D IIAE+
Sbjct: 315 YMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSIIAEV 374
Query: 279 KAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVEN 338
+AQY+DI RS+AEAE+ Y++K E++ T RHG+ LR TK EI ELNRMIQRL AE+E
Sbjct: 375 RAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAEIEG 434
Query: 339 AKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLG 398
K QN+ L+ A+A++EQ GE AL DA KL EL+ ALQ+AK D+A L+R+YQE+MN KL
Sbjct: 435 VKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNVKLA 494
Query: 399 LDIEIATYRRLLEGEEQRL---CEGVGSVNVCVSSS 431
LD+EIATYR+LLEGEE R+ C S++V SS+
Sbjct: 495 LDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSST 530
>gi|67782365 keratin 7 [Homo sapiens]
Length = 469
Score = 407 bits (1046), Expect = e-113
Identities = 224/420 (53%), Positives = 296/420 (70%), Gaps = 6/420 (1%)
Query: 43 GGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 102
GG GS S+ G G+ RS GP I V++N+SLL PL L+ DP+ Q V
Sbjct: 32 GGLGSSSLYG---LGASRPRVAVRSA-YGGPVGAGIREVTINQSLLAPLRLDADPSLQRV 87
Query: 103 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEP-LFEGYIET 161
+QEE EQIK+LN++FA+FIDKVRFLEQQNKLLETK Q ++ +S+ P +FE I
Sbjct: 88 RQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRLPDIFEAQIAG 147
Query: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221
LR + E ++ D GRL +EL +Q+V+E +K KYE+E++ R AENEFV LKKDVD AY+
Sbjct: 148 LRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMS 207
Query: 222 KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281
K +LEA V+AL EI+FLR L E E+ LQS ISDTSVV+ +DNSR L++D IIAE+KAQ
Sbjct: 208 KVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQ 267
Query: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341
Y+++ SRAEAE+WY++K E ++A +HG+ LR T+ EI+E+NR IQRL AE++N K
Sbjct: 268 YEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKN 327
Query: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401
Q +KLEAA+A++E++GE AL DAR K ELE ALQ+ KQDMA +REYQE+M+ KL LDI
Sbjct: 328 QRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDI 387
Query: 402 EIATYRRLLEGEEQRLC-EGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNS 460
EIATYR+LLEGEE RL +GVG+VN+ V +S GG G T + + S S++
Sbjct: 388 EIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGIGLTLGGTMGSNALSFSSSA 447
>gi|109255249 keratin 4 [Homo sapiens]
Length = 594
Score = 404 bits (1039), Expect = e-113
Identities = 228/467 (48%), Positives = 309/467 (66%), Gaps = 35/467 (7%)
Query: 8 GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSV----------------- 50
G R FSC SA R ++ G R +GGFGS S+
Sbjct: 85 GPRGFSCGSAIVGGGKRGAFSSVSMSG-GAGRCSSGGFGSRSLYNLRGNKSISMSVAGSR 143
Query: 51 -------CGGFRAGSCGRSFGYRSGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPN 98
GGF G G FG G GP P C I V++N+SLLTPL++EIDP
Sbjct: 144 QGACFGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDPE 203
Query: 99 AQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFE 156
Q V+ EE+EQIK LN++FA+FIDKV+FLEQQNK+LETK Q + S NLEPLFE
Sbjct: 204 IQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFE 263
Query: 157 GYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVD 216
Y+ LR++ + + D GRL SEL +Q+ +E +K KYEEE++ R AEN+FV LKKDVD
Sbjct: 264 TYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVD 323
Query: 217 CAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIA 276
AYL K +LEA V++L EI+FL+ LY+ E+ +Q+H+SDTSVV+ +DN+R+L++D IIA
Sbjct: 324 AAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIA 383
Query: 277 EIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEV 336
E++AQY++I RS+AEAE+ Y++K ++++ +V +HG+ L+ TK EI ELNRMIQRL AE+
Sbjct: 384 EVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEI 443
Query: 337 ENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSK 396
EN K Q L+ +VA +EQ+GE AL DA K ELE ALQ+AK+++A ++REYQE+M+ K
Sbjct: 444 ENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVK 503
Query: 397 LGLDIEIATYRRLLEGEEQRL---CEGVGSVNVCVSSSRGGVVCGDL 440
L LDIEIATYR+LLEGEE R+ C+ S++V S+ G + G L
Sbjct: 504 LALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGL 550
>gi|15618995 keratin 71 [Homo sapiens]
Length = 523
Score = 402 bits (1033), Expect = e-112
Identities = 228/464 (49%), Positives = 314/464 (67%), Gaps = 35/464 (7%)
Query: 10 RAFSCISACGPRPGRCCITAAPYRGISCY-----RGLTGGFGSHSV--CGGFR----AGS 58
R F+C S + G +A G S +GL+GGFGS S+ GG R A
Sbjct: 3 RQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASG 62
Query: 59 CGRSFGY-----RSGGVCGP-------SPPCITT--------VSVNESLLTPLNLEIDPN 98
G+S GY R+ G G P C T V+VNESLL PLN+E+DP
Sbjct: 63 SGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPE 122
Query: 99 AQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFE 156
Q V+ +E+EQIK+LN++FA+FIDKVRFLEQQN++LETK + Q + C++NLEP+ E
Sbjct: 123 IQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILE 182
Query: 157 GYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVD 216
GYI LR++ E + D RL SEL +V++V+E YKK+YEEE++ R AENEFV LKKDVD
Sbjct: 183 GYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVD 242
Query: 217 CAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIA 276
AY K +L+A VE++ QEI F R L+E EI +QSHISD SV++ +DN+R+L++D II
Sbjct: 243 AAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIID 302
Query: 277 EIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEV 336
E++ QY++I +S+AEAE+ Y++K +E++ RHG+ L+ TK EI+EL R+IQR+ +E+
Sbjct: 303 EVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEI 362
Query: 337 ENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSK 396
EN K Q S LE A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+M+ K
Sbjct: 363 ENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLK 422
Query: 397 LGLDIEIATYRRLLEGEEQRLC-EGVGSVNV-CVSSSRGGVVCG 438
L LD+EIATYR+LLE EE R+ E V++ +SS+ GG V G
Sbjct: 423 LALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGSVYG 466
>gi|28173564 keratin 73 [Homo sapiens]
Length = 540
Score = 396 bits (1018), Expect = e-110
Identities = 211/398 (53%), Positives = 291/398 (73%), Gaps = 9/398 (2%)
Query: 40 GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEID 96
G GG+G G +G G FG + G PS P I V++N+SLL PLN+E+D
Sbjct: 66 GWAGGYGFGR---GRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELD 122
Query: 97 PNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPL 154
P Q V+ +E+EQIK LN++FA+FIDKVRFLEQQN++LETK + Q + C++NLEP+
Sbjct: 123 PEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPI 182
Query: 155 FEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKD 214
EGYI LR++ E + D RL SEL V+EV+E YKK+YEEE++ R TAENEFV LKKD
Sbjct: 183 LEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKD 242
Query: 215 VDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCI 274
VD AY K +L+A V+AL EI F + LYE E +QSHISDTS+++ +DN+R+L++D I
Sbjct: 243 VDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSI 302
Query: 275 IAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTA 334
IAE++AQY++I +S+AEAE+ Y++K +E++ RHG+ L+ TK EI+EL R+IQRL +
Sbjct: 303 IAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRS 362
Query: 335 EVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMN 394
E+E+ K Q + LE A+A +EQ+G+ AL DAR KL ELEGALQ+AK+++A ++REYQE+++
Sbjct: 363 EIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLS 422
Query: 395 SKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431
KL LDIEIATYR+LLEGEE R+ E SV++ V +S
Sbjct: 423 VKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINS 460
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 394 bits (1012), Expect = e-109
Identities = 210/393 (53%), Positives = 291/393 (74%), Gaps = 8/393 (2%)
Query: 43 GGFGSHSVCGGFRAGSCGRS-FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQC 101
GGFGS GGF G G +G G VC P I V++N+SLL PLN+EIDP Q
Sbjct: 120 GGFGSGG--GGFGGGGFGGGGYGGGYGPVCPPGG--IQEVTINQSLLQPLNVEIDPEIQK 175
Query: 102 VKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFEGYI 159
VK E+EQIKSLN++FA+FIDKVRFLEQQN++L+TK + Q + NLEP FE +I
Sbjct: 176 VKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFI 235
Query: 160 ETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAY 219
LRR + +++D RL SEL ++Q+++E Y+ KYE+E++ R AENEFV +KKDVD AY
Sbjct: 236 NNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAY 295
Query: 220 LRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIK 279
+ K DL+A ++ L QEIDFL LY+ E+ +Q+ IS+T+V++ +DN+R L++D IIAE+K
Sbjct: 296 MTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVK 355
Query: 280 AQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENA 339
AQY+DI +S+AEAES Y+SK EE++ T RHG+++R +K EI+ELNR+IQRL +E++N
Sbjct: 356 AQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNV 415
Query: 340 KCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGL 399
K Q S L+ +++ +EQ+GE AL DA+ KL +LE ALQ+AK+D+A L+R+YQE+MN+KL L
Sbjct: 416 KKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLAL 475
Query: 400 DIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431
D+EIATYR LLEGEE R+ E +V+V VS+S
Sbjct: 476 DLEIATYRTLLEGEESRMSGECAPNVSVSVSTS 508
>gi|153791670 keratin 76 [Homo sapiens]
Length = 638
Score = 392 bits (1008), Expect = e-109
Identities = 211/392 (53%), Positives = 280/392 (71%), Gaps = 9/392 (2%)
Query: 40 GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNA 99
G GGFG V GG GS G G+ GG P I V VN+SLL PLN+EIDP
Sbjct: 123 GGAGGFGGPGVFGG--PGSFGGPGGFGPGGF----PGGIQEVIVNQSLLQPLNVEIDPQI 176
Query: 100 QCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ--SNLEPLFEG 157
VK +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK + Q + S+LEP FE
Sbjct: 177 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFES 236
Query: 158 YIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDC 217
YI L ++ + + + G L EL +Q+++E +KKKYE+E++ R AENEFV LKKDVD
Sbjct: 237 YISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDA 296
Query: 218 AYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAE 277
A++ K +L+A V++L E+ FLR LYE E+ +QSH SDTSVV+ +DN+R L++ IIAE
Sbjct: 297 AFMNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAE 356
Query: 278 IKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVE 337
++AQY++I RS++EAE+ Y++K E++ T RHG+ LR TK EI ELNRMIQRL AE+E
Sbjct: 357 VRAQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIE 416
Query: 338 NAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKL 397
N K QN+ L+ A+A++EQ+GE AL DA KL +L+ ALQKAK D+A L+R+YQE+MN KL
Sbjct: 417 NVKKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKL 476
Query: 398 GLDIEIATYRRLLEGEEQRLCEGVGSVNVCVS 429
LD+EIATYR+LLEGEE R+ G VC+S
Sbjct: 477 ALDVEIATYRKLLEGEECRM-SGECQSAVCIS 507
>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 391 bits (1005), Expect = e-109
Identities = 204/386 (52%), Positives = 286/386 (74%), Gaps = 6/386 (1%)
Query: 52 GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 108
GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+ +E+E
Sbjct: 68 GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127
Query: 109 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREA 166
QIK+LN++FA+FIDKVRFLEQQN++LETK Q + C+ NLEP++EGYI L+++
Sbjct: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187
Query: 167 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLE 226
E + D RL SEL ++Q+++E YKK+YE E++ R AENEFV LKKDVD AY+ K +L+
Sbjct: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247
Query: 227 ANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIV 286
A V++L EI F + LYE EI +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I
Sbjct: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307
Query: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346
+S+AEAE+ Y++K +E++ T +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + L
Sbjct: 308 LKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADL 367
Query: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406
E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 368 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 427
Query: 407 RRLLEGEEQRLC-EGVGSVNVCVSSS 431
R+LLE EE R+ E SV++ V SS
Sbjct: 428 RKLLESEECRMSGEYPNSVSISVISS 453
>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 391 bits (1005), Expect = e-109
Identities = 204/386 (52%), Positives = 286/386 (74%), Gaps = 6/386 (1%)
Query: 52 GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 108
GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+ +E+E
Sbjct: 68 GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127
Query: 109 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREA 166
QIK+LN++FA+FIDKVRFLEQQN++LETK Q + C+ NLEP++EGYI L+++
Sbjct: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187
Query: 167 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLE 226
E + D RL SEL ++Q+++E YKK+YE E++ R AENEFV LKKDVD AY+ K +L+
Sbjct: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247
Query: 227 ANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIV 286
A V++L EI F + LYE EI +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I
Sbjct: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307
Query: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346
+S+AEAE+ Y++K +E++ T +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + L
Sbjct: 308 LKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADL 367
Query: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406
E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 368 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 427
Query: 407 RRLLEGEEQRLC-EGVGSVNVCVSSS 431
R+LLE EE R+ E SV++ V SS
Sbjct: 428 RKLLESEECRMSGEYPNSVSISVISS 453
>gi|32567786 keratin 6L [Homo sapiens]
Length = 535
Score = 389 bits (999), Expect = e-108
Identities = 218/441 (49%), Positives = 297/441 (67%), Gaps = 35/441 (7%)
Query: 34 GISCYRGLTGGFGSHS-------------VCGGFRAGSCGRSFGYRSGGVCGPS------ 74
G C G TGGFGS S V GG G FG+ S G
Sbjct: 47 GAHCGPG-TGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTF 105
Query: 75 -PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQ 129
P C I V+VN+SLLTPL++EIDP Q V+ +E+EQIK+LN++FA+FIDKVRFLEQ
Sbjct: 106 GPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQ 165
Query: 130 QNKLLETKLQFYQ----NRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQE 185
QNK+LETK Q N ++NLEPLFE Y+ ++R + ++++ GRL SEL +VQ+
Sbjct: 166 QNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQD 225
Query: 186 VLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 245
++E +K KYE+E++ AENEFV LKKDVD AY+ + DL V L QEIDFL++LYE
Sbjct: 226 LVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEM 285
Query: 246 EIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMK 305
E+ +Q+H+S+T+VV+ +DN+R+L++D IIAE+KAQY+ I RSRAEAE+WY++K EE++
Sbjct: 286 ELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQ 345
Query: 306 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 365
T +HG+ LR TK EI EL R IQRL E + AK Q +L+ A+A++EQ+GE AL DA+
Sbjct: 346 VTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQ 405
Query: 366 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL---CEGVG 422
KL +L+ AL +AK+D+ L+R+YQE+MN KL LD+EIATYR+LLE EE R+ C
Sbjct: 406 KKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAV 465
Query: 423 SVNVCVSSSRGGVVCGDLCAS 443
S++V +S+ VCG AS
Sbjct: 466 SISVTGNST---TVCGGGAAS 483
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 381 bits (979), Expect = e-106
Identities = 225/484 (46%), Positives = 314/484 (64%), Gaps = 35/484 (7%)
Query: 8 GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRS 67
GG F G R G + + G S + G GGFG GG R G G G
Sbjct: 79 GGGGFGAAGGFGGRGGGFG-GGSSFGGGSGFSG--GGFGGGGFGGG-RFGGFGGPGGV-- 132
Query: 68 GGVCGPS-------PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
GG+ GP P I VSVN+SLL PLN+++DP Q VK +E+EQIK+LN++FA+F
Sbjct: 133 GGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASF 192
Query: 121 IDKVRFLEQQNKLLETKLQFYQ--NRECCQSNLEPLFEGYIETLRREAECVEADSGRLAS 178
IDKVRFLEQQN++L+TK + Q N NLEP+F+GYI++L+R + + A+ S
Sbjct: 193 IDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNS 252
Query: 179 ELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDF 238
ELN++Q+++E YKKKYE+E++ R AEN+FV LKKDVD AY+ K +L++ V+ L QEI+F
Sbjct: 253 ELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEF 312
Query: 239 LRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYR 298
L+ LY+ EI + ++DT+V++ +DNSR+L++D IIAE+KAQY++I RS+ EAE+ Y
Sbjct: 313 LKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYH 372
Query: 299 SKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGE 358
SK EE++ TV RHG++L+ K EI+ELNR+IQRL E+ + K Q ++ A+A +EQ+GE
Sbjct: 373 SKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGE 432
Query: 359 AALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC 418
AL DAR KL +LE ALQ+AK+D+A L+R+YQE+MN KL LD+EIATYR+LLEGEE R+
Sbjct: 433 HALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRM- 491
Query: 419 EGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGV 478
GDL ++ T V S+ +SS + S G + S+ G
Sbjct: 492 ------------------SGDLSSNVTVSVTSSTISSNVA-SKAAFGGSGGRGSSSGGGY 532
Query: 479 CGGS 482
GS
Sbjct: 533 SSGS 536
>gi|148612803 keratin 6 irs4 [Homo sapiens]
Length = 529
Score = 379 bits (973), Expect = e-105
Identities = 203/397 (51%), Positives = 284/397 (71%), Gaps = 11/397 (2%)
Query: 44 GFGSHSVCGGFRA-GSCGRSFGYRSGG-----VCGPSPPCITTVSVNESLLTPLNLEIDP 97
GF S GG RA G G FG + G VC P I V+VN+SLL PLN+E+DP
Sbjct: 74 GFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGG--IHQVTVNKSLLAPLNVELDP 131
Query: 98 NAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLF 155
Q V+ +E+EQIK LN +FA+FIDKVRFLEQQN++LETK + Q + C+ NLEP+
Sbjct: 132 EIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPIL 191
Query: 156 EGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDV 215
EGYI LR++ E + D RL SEL +++++E YKK+YE E++ R TAENEFV LKKD
Sbjct: 192 EGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDA 251
Query: 216 DCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCII 275
D AY K +L+A V++L +EI FL+ LY+ EI +Q+H S+TSV++ +DN+RDL++D II
Sbjct: 252 DAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSII 311
Query: 276 AEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE 335
AE++ Y++I +S+AEAE+ Y++K +E++ RHG+ L+ T+ E+ ELNR+IQR+ E
Sbjct: 312 AEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCE 371
Query: 336 VENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNS 395
+ N K Q + LE A+A +EQ+G+ AL DA+ KL ELEGAL +AK+++A ++REYQE+M+
Sbjct: 372 IGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSL 431
Query: 396 KLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431
KL LD+EIATYR+LLEGEE R+ E SV++ V SS
Sbjct: 432 KLALDMEIATYRKLLEGEECRMSGENPSSVSISVISS 468
>gi|194018511 keratin 77 [Homo sapiens]
Length = 578
Score = 352 bits (904), Expect = 3e-97
Identities = 190/414 (45%), Positives = 283/414 (68%), Gaps = 15/414 (3%)
Query: 37 CYRGLTGGFGS-------HSVCGGFRAGSCGRS-FGYRSGGVCGPSPPC----ITTVSVN 84
C G GGFG + GGF G G + FG + G+ G P C I V++N
Sbjct: 83 CQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTIN 142
Query: 85 ESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ-- 142
+SLL PL+LE+DP Q +K +E+EQI LN++FA+FIDKVRFLEQQN++L+TK + Q
Sbjct: 143 QSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQV 202
Query: 143 NRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRA 202
N +NLEPL E YI LRR+ + + A+ R +E+ +Q+V+E YK KYE+E++ R
Sbjct: 203 NTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRT 262
Query: 203 TAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVK 262
+EN+FV LKKDVD AY+ K DLE+ V+ L E++FL+ L+ E+ +Q+HISDT+V++
Sbjct: 263 GSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILS 322
Query: 263 LDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEI 322
+DN+R L++D II ++ QY+ I RS+ EAE+ Y++K +E++ T RHG+ L+ +K EI
Sbjct: 323 MDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEI 382
Query: 323 NELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDM 382
ELNR +QRL AE+ N K Q ++++ ++ +E++GE AL DA KL +LE ALQ++K+++
Sbjct: 383 AELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEEL 442
Query: 383 ACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGS-VNVCVSSSRGGV 435
A L+R+YQ ++ KL LD+EIATYR+LLEGEE R+ + S V++ V +S+ V
Sbjct: 443 ARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSV 496
>gi|89357932 keratin 5b [Homo sapiens]
Length = 520
Score = 346 bits (887), Expect = 3e-95
Identities = 214/498 (42%), Positives = 303/498 (60%), Gaps = 29/498 (5%)
Query: 10 RAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGR---SFGYR 66
R FS SAC R RG R L G G GS GR FG
Sbjct: 10 RGFSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEW 69
Query: 67 SGG----VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFID 122
SGG +C P I V++N++LLTPL +EIDP Q V+ +E ++I++LN++FA+FID
Sbjct: 70 SGGPGLSLCPPGG--IQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFID 127
Query: 123 KVRFLEQQNKLLETKLQFYQNRECC--QSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
KVRFLEQQNK+LETK Q + Q LEP+FE ++ LR++ E ++ + G L +EL
Sbjct: 128 KVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAEL 187
Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
++ E YK KYEEE RAT EN+FV LKKDVD +L K +LE +EAL + + FL+
Sbjct: 188 KACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLK 247
Query: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
L EEE+ LQ+ SDTSVV+ +DN+R L+ II E++A+Y++I S+AEAE+ Y++K
Sbjct: 248 HLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTK 307
Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
+E++ + HG+ ++ TK +I++L++ IQRL ++ EN K QN+ L+AA+ +EQ+GE A
Sbjct: 308 YQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELA 367
Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
L DA+ K+ ELE AL+ AKQ++A L+ EYQE+ ++KL LD+EIATYRRLLEGEE R+ G
Sbjct: 368 LKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRM-SG 426
Query: 421 VGSVNVCVSSSRGGVV--------CGDLC--ASTTAPVVSTRVSSVPSNSNVVVGT---- 466
+ V +SS G V G C S S S V SN+++G+
Sbjct: 427 ECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDP 486
Query: 467 -TNACAPSARVGVCGGSC 483
++C+ S G SC
Sbjct: 487 VLDSCSVSG--SSAGSSC 502
>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
Length = 469
Score = 335 bits (859), Expect = 5e-92
Identities = 185/386 (47%), Positives = 256/386 (66%), Gaps = 48/386 (12%)
Query: 52 GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 108
GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+ +E+E
Sbjct: 68 GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127
Query: 109 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREA 166
QIK+LN++FA+FIDKVRFLEQQN++LETK Q + C+ NLEP++EGYI L+++
Sbjct: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187
Query: 167 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLE 226
E + D RL SEL ++Q+++E YKK+YE E++ R AENEFV LKKDVD AY+ K +L+
Sbjct: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247
Query: 227 ANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIV 286
A V++L EI F + LYE EI +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I
Sbjct: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307
Query: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346
+S+AEAE+ Y++KC + L
Sbjct: 308 LKSKAEAETLYQTKCAD------------------------------------------L 325
Query: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406
E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 326 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 385
Query: 407 RRLLEGEEQRLC-EGVGSVNVCVSSS 431
R+LLE EE R+ E SV++ V SS
Sbjct: 386 RKLLESEECRMSGEYPNSVSISVISS 411
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,851,769
Number of Sequences: 37866
Number of extensions: 797553
Number of successful extensions: 5788
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 160
Number of HSP's successfully gapped in prelim test: 466
Number of HSP's that attempted gapping in prelim test: 4068
Number of HSP's gapped (non-prelim): 1525
length of query: 486
length of database: 18,247,518
effective HSP length: 106
effective length of query: 380
effective length of database: 14,233,722
effective search space: 5408814360
effective search space used: 5408814360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.