BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14249338 BUD13 homolog isoform 1 [Homo sapiens] (619 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14249338 BUD13 homolog isoform 1 [Homo sapiens] 1276 0.0 gi|229577273 BUD13 homolog isoform 2 [Homo sapiens] 615 e-176 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 76 1e-13 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 76 1e-13 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 74 4e-13 gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap... 68 2e-11 gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 68 3e-11 gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 65 1e-10 gi|217330641 IWS1 homolog [Homo sapiens] 64 5e-10 gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 62 2e-09 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 59 1e-08 gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 57 4e-08 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 56 9e-08 gi|50962882 G patch domain containing 8 [Homo sapiens] 56 9e-08 gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 56 9e-08 gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 55 1e-07 gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 55 2e-07 gi|78042577 MAP7 domain containing 1 [Homo sapiens] 54 4e-07 gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 54 6e-07 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 53 7e-07 gi|50083281 KIAA1853 protein [Homo sapiens] 53 7e-07 gi|163965366 nascent polypeptide-associated complex alpha subuni... 53 7e-07 gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 52 1e-06 gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 52 2e-06 gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 52 2e-06 gi|168229156 NFKB activating protein [Homo sapiens] 51 4e-06 gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 51 4e-06 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 50 5e-06 gi|16445033 ACRC protein [Homo sapiens] 50 5e-06 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 50 5e-06 >gi|14249338 BUD13 homolog isoform 1 [Homo sapiens] Length = 619 Score = 1276 bits (3302), Expect = 0.0 Identities = 619/619 (100%), Positives = 619/619 (100%) Query: 1 MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA 60 MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA Sbjct: 1 MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA 60 Query: 61 ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120 ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR Sbjct: 61 ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120 Query: 121 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI 180 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI Sbjct: 121 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI 180 Query: 181 RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISS 240 RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISS Sbjct: 181 RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISS 240 Query: 241 PRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSP 300 PRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSP Sbjct: 241 PRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSP 300 Query: 301 HWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPR 360 HWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPR Sbjct: 301 HWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPR 360 Query: 361 HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAA 420 HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAA Sbjct: 361 HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAA 420 Query: 421 HMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQ 480 HMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQ Sbjct: 421 HMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQ 480 Query: 481 RRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQER 540 RRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQER Sbjct: 481 RRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQER 540 Query: 541 EGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFAR 600 EGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFAR Sbjct: 541 EGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFAR 600 Query: 601 LASKKAVEELAYKWSVEDM 619 LASKKAVEELAYKWSVEDM Sbjct: 601 LASKKAVEELAYKWSVEDM 619 >gi|229577273 BUD13 homolog isoform 2 [Homo sapiens] Length = 485 Score = 615 bits (1586), Expect = e-176 Identities = 325/438 (74%), Positives = 342/438 (78%), Gaps = 64/438 (14%) Query: 184 SSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRR 243 + D R RHD+PD +SPRRVRH +PDPSP R+ RH + D SPRR Sbjct: 110 NEDLPSNRHFRHDTPD-------------SSPRRVRHGTPDPSP-RKDRHDTPD-PSPRR 154 Query: 244 VHNNSPDTS--RRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPH 301 +++PD S R SDT RR RHDS D +P Sbjct: 155 ARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSP------------------------- 189 Query: 302 WKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRH 361 P+ ++++ PD SPPR+ Q +S GDCQKATDSDLSSPRH Sbjct: 190 -----------PRRARHD-SPDPSPPRRPQH----------NSSGDCQKATDSDLSSPRH 227 Query: 362 KQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAH 421 KQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAH Sbjct: 228 KQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAH 287 Query: 422 MYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQR 481 MYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQR Sbjct: 288 MYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQR 347 Query: 482 RKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQERE 541 RKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQERE Sbjct: 348 RKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQERE 407 Query: 542 GDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARL 601 GDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARL Sbjct: 408 GDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARL 467 Query: 602 ASKKAVEELAYKWSVEDM 619 ASKKAVEELAYKWSVEDM Sbjct: 468 ASKKAVEELAYKWSVEDM 485 Score = 459 bits (1182), Expect = e-129 Identities = 255/442 (57%), Positives = 292/442 (66%), Gaps = 25/442 (5%) Query: 1 MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA 60 MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA Sbjct: 1 MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA 60 Query: 61 ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120 ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR Sbjct: 61 ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120 Query: 121 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI 180 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI Sbjct: 121 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI 180 Query: 181 RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARH--GSSDI 238 RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSG + D P + H SD+ Sbjct: 181 RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDL 240 Query: 239 SSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASS-- 296 S PR N P S ++ +R + DL+P P K+ A + Sbjct: 241 SPPR----NRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGL 296 Query: 297 ------KTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQK 350 + KE ++F ++++Y + R K + ++L+ + +K Sbjct: 297 VLTDIQREQQELKEQDQETMAF--EAEFQYAETVF--RDKSGRKRNLKLERLEQRRKAEK 352 Query: 351 ATDSD-LSSPRHK---QSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSD--- 403 ++ D L + K QS Q + D +P R D + R++ + D Sbjct: 353 DSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMA 412 Query: 404 SDLSPPRRSQPPGKKAAHMYSG 425 + + + + KK YSG Sbjct: 413 NFIKKNKAKENKNKKVRPRYSG 434 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 75.9 bits (185), Expect = 1e-13 Identities = 88/294 (29%), Positives = 115/294 (39%), Gaps = 45/294 (15%) Query: 114 PSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSD 173 P+ R R TP + RR R TP R+ R + P+ RR+R SP+R R Sbjct: 589 PARRRSRSRTP--TRRRSRSRTP---ARRGRSRSRTPARRRSR----TRSPVR--RRSRS 637 Query: 174 TSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARH 233 SP RR S T P RR R S +P RR + S + R R S P AR Sbjct: 638 RSPARRSGRSRSRT-PARRGR--SRSRTPARRGRSRSRTPARRSGRSRSRTP-----ARR 689 Query: 234 GSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPER 293 G S +PRR + S RR S T Q R S + S R++S +PE Sbjct: 690 GRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEM 749 Query: 294 ASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATD 353 S+ S S +S PR K AKS ++ L C K Sbjct: 750 KKSRISSRRSRS------------------LSSPRSK-AKSRLSLRRSLSGSSPCPK--Q 788 Query: 354 SDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLS 407 + PR +S Q +PPR RS S PP+++ +T S S S Sbjct: 789 KSQTPPRRSRSGSSQPKAKSRTPPR-----RSRSSSSPPPKQKSKTPSRQSHSS 837 Score = 68.9 bits (167), Expect = 1e-11 Identities = 142/643 (22%), Positives = 218/643 (33%), Gaps = 111/643 (17%) Query: 28 SESGRKRRKKR-PKPGGAGGKGMRIVDDDVSWTAISTTKLEKEEEEDDGDLPVVAEFVDE 86 SES K+RK R P P K R D + STT K A D Sbjct: 220 SESESKKRKHRSPTP-----KSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDT 274 Query: 87 RPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRV---RHGTPDPSPR-- 141 + A + L G + S R D P S P R +P+ + + Sbjct: 275 SRSRSRSAAAKTHTTA---LAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQP 331 Query: 142 --------KDRHDT----PDPSPRRARH--DTPDPSPLRGARHDSDTSP----------- 176 KD+ + P PSP R+ + P P+PL RH P Sbjct: 332 SSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPV 391 Query: 177 -PRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGS 235 P + D SPP+ SP + PQ +SS +SP P P P + +RH S Sbjct: 392 NPPSEASPTRDRSPPK---------SPEKLPQSSSSESSP-------PSPQPTKVSRHAS 435 Query: 236 SDISSPR--------RVHNNSPDTSRRTLG-------SSDTQQLRRARHDSPDLAPNVTY 280 S SP+ R ++SP + R+ G S T R R SP T Sbjct: 436 SSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSP-----ATA 490 Query: 281 SLPRTKSGKAPERASSKT-SPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDK 339 R++S +R S++ SP W+ S ++ S SP R ++S Sbjct: 491 KRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRS----- 545 Query: 340 KQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQR- 398 + +G + A H +SP + +P R R R RS +P RRR R Sbjct: 546 RNTQRRGRSRSAR----RGRSHSRSPATRGRSRSRTPAR-RGRSRSR----TPARRRSRS 596 Query: 399 ---TKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAE 455 T+ +P RR + + A S ++ + R + + Sbjct: 597 RTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRG 656 Query: 456 FQYAETVFR----------DKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSR 505 + T R +SGR R+ R + R R + +G + SR Sbjct: 657 RSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSR 716 Query: 506 QQQQNVEDAMKEMQKPLARYIDDEDLDRMLRE--QEREGDPMANFIKKNKAKENKNKKVR 563 Q+ +K +R E + R + + ++K +R Sbjct: 717 TPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLR 776 Query: 564 PRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARLASKKA 606 SG +P P + + P R RS + K +R +++ Sbjct: 777 RSLSGSSPCPKQKSQTPPRR----SRSGSSQPKAKSRTPPRRS 815 Score = 61.6 bits (148), Expect = 2e-09 Identities = 89/374 (23%), Positives = 138/374 (36%), Gaps = 56/374 (14%) Query: 70 EEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPR 129 +EE G P V E K+ E R++ G ++ F P R Sbjct: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAF------GISDSYVDGSSF---DPQRRAR 158 Query: 130 RVRHGTPDP--------SPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIR 181 + P+P R TP ++ + D RG R S++S PRR R Sbjct: 159 EAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKD-------RGRR--SESSSPRRER 209 Query: 182 HDSS------DTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGS 235 SS S ++ +H SP P R+ + +R R S P+P R H S Sbjct: 210 KKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDK------KRKRSRSTTPAPKSRRAHRS 263 Query: 236 SDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERAS 295 + S +S DTSR S ++ H + + + + R G AP Sbjct: 264 TSADSA-----SSSDTSR-----SRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEP 313 Query: 296 SKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSD 355 TS S + P + + D D +K+++ + + S G + + Sbjct: 314 GTTSTQRPSSPETATKQPSSPYEDKDKD----KKEKSATRPSPSPERSSTGP-EPPAPTP 368 Query: 356 LSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQR-TKSSDSDLSPPRRSQP 414 L + RH SP + P N P S D SPP+ ++ +SS S+ SPP S Sbjct: 369 LLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPP--SPQ 426 Query: 415 PGKKAAHMYSGAKT 428 P K + H S ++ Sbjct: 427 PTKVSRHASSSPES 440 Score = 61.6 bits (148), Expect = 2e-09 Identities = 93/331 (28%), Positives = 126/331 (38%), Gaps = 68/331 (20%) Query: 128 PRRVRHGTPDP------SPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIR 181 PRR R + P +P + H + P P + + TP R S TSP Sbjct: 812 PRRSRSSSSPPPKQKSKTPSRQSHSSSSPHP-KVKSGTP-------PRQGSITSPQ---A 860 Query: 182 HDSSDTSPPRRARHDSPDPSPPRR--PQHNSSGASPRRV-----------RHDSPDP--- 225 ++ S T R SPDP R +H+ SG+SP RV R SP P Sbjct: 861 NEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVK 920 Query: 226 ---SPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQ--LRRARHD---------S 271 SP +R+ GSS S R +P SR S+ + L R H Sbjct: 921 AIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVK 980 Query: 272 PDLAPNVTYS-----LPRTKSGKAPE---RASSKTSPHWKESGASHLSFPKNSKYEYDPD 323 P+ P ++S P+ K+ P S P K + S P + Sbjct: 981 PETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVK 1040 Query: 324 ISPPRKKQAKSHFGDKKQLDSKGDCQKATD--SDLSSPR----HKQSPGHQDSDSDLSPP 377 S P +S+FG L KG Q + D SD SSP H +SP Q S S SP Sbjct: 1041 SSTP---PGESYFG-VSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQ-SKSQTSPK 1095 Query: 378 RNRPRHRSSDSDLS--PPRRRQRTKSSDSDL 406 R R S ++L+ P R+ R + S S + Sbjct: 1096 GGRSRSSSPVTELASRSPIRQDRGEFSASPM 1126 Score = 60.8 bits (146), Expect = 3e-09 Identities = 83/317 (26%), Positives = 117/317 (36%), Gaps = 52/317 (16%) Query: 127 SPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTP---DPSPLRGARHDSDTSPPRRIRHD 183 +P+R R G+ +K TP R+ PS R +SD+SP + + Sbjct: 1511 TPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAK-- 1568 Query: 184 SSDTSPPRRARH--------DSPDPSPPRRPQHNSSG-------ASPRRVRHDSPDPSP- 227 T P R R DS PRR + SS A+PR P P Sbjct: 1569 ---TRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPK 1625 Query: 228 -------PRRARHGSSDISSPRRVHNNSPDTSRRTLGSSD----TQQLRRARHDSPDLAP 276 PRR+R GSS + SP+ S T S + ++ RR SP+ Sbjct: 1626 APAPRALPRRSRSGSSS-----KGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPE--- 1677 Query: 277 NVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHF 336 P+TKS P R SS++SP S +PPR +++ S Sbjct: 1678 ------PKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVS 1731 Query: 337 GDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRR 396 + S+ ++ + SSPR K + S S R R RS RRR Sbjct: 1732 SPEPAEKSRSSRRRRS---ASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRR 1788 Query: 397 QRTKSSDSDLSPPRRSQ 413 R+ SS S +RS+ Sbjct: 1789 DRSGSSQSTSRRRQRSR 1805 Score = 57.4 bits (137), Expect = 4e-08 Identities = 98/377 (25%), Positives = 132/377 (35%), Gaps = 68/377 (18%) Query: 98 RSSAKWKLLGGHNEDLPSNR-HFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPR-RA 155 RS + + G P+ R R TP RR R + P+ R R + P+ R R+ Sbjct: 636 RSRSPARRSGRSRSRTPARRGRSRSRTP---ARRGRSRSRTPARRSGRSRSRTPARRGRS 692 Query: 156 RHDTP------DPSPLRGARHDSDTSPPRRIRHDSSD-------TSPPRRARHDSPDPSP 202 R TP S +R R S T P RR R SS TS R + SP+ Sbjct: 693 RSRTPRRGRSRSRSLVRRGRSHSRT-PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKK 751 Query: 203 PRRPQHNSSGASP------------RRVRHDSPDP-----SPPRRARHGSSDISSPRRVH 245 R S S R + SP P +PPRR+R GSS P+ Sbjct: 752 SRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQ---PKAKS 808 Query: 246 NNSPDTSRRTLGSSDTQQLRR-ARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKE 304 P SR + Q+ + +R +P+ P+ KSG P R S TSP E Sbjct: 809 RTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH-----PKVKSG-TPPRQGSITSPQANE 862 Query: 305 SGASHLSFPKNSKYEYDPD---------------ISPPRKKQAKSHFGDKKQLDSKGDCQ 349 + + S +E PD SPPR K + +Q S+ Sbjct: 863 QSVTP---QRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTP----PRQSPSRSSSP 915 Query: 350 KATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPP 409 + + SPR + G R PR S S S R + S S S P Sbjct: 916 QPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSP 975 Query: 410 RRSQPPGKKAAHMYSGA 426 P +SG+ Sbjct: 976 DTKVKPETPPRQSHSGS 992 Score = 57.0 bits (136), Expect = 5e-08 Identities = 100/413 (24%), Positives = 148/413 (35%), Gaps = 40/413 (9%) Query: 1 MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA 60 +++ P K+ +R S A R + R+ R PKP G R Sbjct: 1730 VSSPEPAEKSRSSRRRRS---ASSPRTKTTSRRGRSPSPKPRGLQRSRSR---------- 1776 Query: 61 ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120 ++ EK D ++ R +Q RS + GG S Sbjct: 1777 ---SRREKTRTTRRRDRSGSSQSTSRR----RQRSRSRSRVTRRRRGGSGYHSRSPARQE 1829 Query: 121 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI 180 S RR R TP P+ RK P+P + P+ R +R + RR Sbjct: 1830 SSRTSSRRRRGRSRTP-PTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRS 1888 Query: 181 RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISS 240 R S TSP R R S RR + +S S RR R +P P R R S ++ Sbjct: 1889 R---SRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTP---PVTRRRSRSRTPTT 1942 Query: 241 PRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERAS-SKTS 299 RR + +P +RR S RR S +T R+++ R S S+TS Sbjct: 1943 RRRSRSRTPPVTRRRSRSRTPPVTRRR---SRSRTSPITRRRSRSRTSPVTRRRSRSRTS 1999 Query: 300 PHWKESGASHLS--FPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLS 357 P + S S + S+ P I R+ ++++ +K+ S+ S Sbjct: 2000 PVTRRRSRSRTSPVTRRRSRSRTPPAIR--RRSRSRTPLLPRKRSRSRSPLAIRRRSRSR 2057 Query: 358 SPRHKQSPGHQDSDSDLSPPRNRPRHRS-SDSDLSPPRRRQRTKSSDSDLSPP 409 +PR + SPP R R S S SD S T++ +PP Sbjct: 2058 TPRTARG----KRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPP 2106 Score = 54.7 bits (130), Expect = 2e-07 Identities = 83/329 (25%), Positives = 114/329 (34%), Gaps = 58/329 (17%) Query: 125 DSSPRRVRHGTPDPSPRKDRHDTPDP-----SPRRARHDTPDPSPLRGAR-----HDSDT 174 +SSP H + R+ +P+P +P R R P R AR + + Sbjct: 1656 ESSPE---HPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASS 1712 Query: 175 SPPRRIRHDSSDTSPPRRARH---DSPDPSPPRRPQHNSSGASPRRV-----RHDSPDPS 226 SP R R +PPR R SP+P+ R AS R R SP P Sbjct: 1713 SPETRSR------TPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK 1766 Query: 227 P------------------PRRARHGSSDISSPRRVHNNSPD-TSRRTLGSSDTQQLRRA 267 P RR R GSS +S RR + S +RR G S A Sbjct: 1767 PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPA 1826 Query: 268 RHDSPDLAPNVTYSLPRTKSGKAPERASSKTSP-HWKESGASHLSFPKNSKYEYDPDISP 326 R +S + RT + +R+ S+TSP WK S + P IS Sbjct: 1827 RQESSRTSSRRRRGRSRTPP-TSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISR 1885 Query: 327 PRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSS 386 R + S ++ + T R + SP + +PP R R RS Sbjct: 1886 RRSRSRTSPVSRRRS-------RSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSR 1938 Query: 387 DSDLSPPRRRQRTKSSDSDLSPPRRSQPP 415 RRR R+++ R PP Sbjct: 1939 ---TPTTRRRSRSRTPPVTRRRSRSRTPP 1964 Score = 52.4 bits (124), Expect = 1e-06 Identities = 71/324 (21%), Positives = 121/324 (37%), Gaps = 27/324 (8%) Query: 126 SSPRRVRHGTPDPSPRKDRHDTPDPSPR-------RARHDTPDPSPLRGARHDSDTSPPR 178 SS RR +P R +P P PR R+R + + R S ++ R Sbjct: 1741 SSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRR 1800 Query: 179 RIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDI 238 R R S RR P R + + + + RR R +P P+ +R+R +S Sbjct: 1801 RQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTP-PTSRKRSRSRTSPA 1859 Query: 239 SSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLA-----PNVTYSLPRTKSGKAP-- 291 R SP T RR+ + RR+R + ++ + + R++S +P Sbjct: 1860 PWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVS 1919 Query: 292 -ERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQK 350 R+ S+T P + S + P ++ R + ++ + Sbjct: 1920 RRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITR 1979 Query: 351 ATDSDLSSP------RHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDS 404 +SP R + SP + + P R R RS +PP R+R++S + Sbjct: 1980 RRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSR----TPPAIRRRSRSR-T 2034 Query: 405 DLSPPRRSQPPGKKAAHMYSGAKT 428 L P +RS+ A S ++T Sbjct: 2035 PLLPRKRSRSRSPLAIRRRSRSRT 2058 Score = 50.8 bits (120), Expect = 4e-06 Identities = 66/251 (26%), Positives = 101/251 (40%), Gaps = 45/251 (17%) Query: 175 SPPRRIRHDSS-----DTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPR 229 +PPRR R SS +PPRR+R S SPP P+ S +P R H S P P Sbjct: 792 TPPRRSRSGSSQPKAKSRTPPRRSRSSS---SPP--PKQKSK--TPSRQSHSSSSPHP-- 842 Query: 230 RARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLP--RTKS 287 + + G + PR+ SP + +++ T Q R SPD P + P + S Sbjct: 843 KVKSG----TPPRQGSITSPQANEQSV----TPQRRSCFESSPD--PELKSRTPSRHSCS 892 Query: 288 GKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGD 347 G +P R S T P S +S P + + +SH G S+ Sbjct: 893 GSSPPRVKSSTPPRQSPSRSS----------SPQPKVKAIISPRQRSHSGSSSPSPSR-- 940 Query: 348 CQKATDSDLSSPRHKQSPGH-QDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDL 406 + ++PR +S + +S L P + S D+ + P +++ S Sbjct: 941 -----VTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISP 995 Query: 407 SPPRRSQ-PPG 416 P ++Q PPG Sbjct: 996 YPKVKAQTPPG 1006 Score = 50.8 bits (120), Expect = 4e-06 Identities = 68/310 (21%), Positives = 110/310 (35%), Gaps = 48/310 (15%) Query: 120 RHDTPDSSPRRVRHGTPDPSPRKDRHDTP----DPSPRRARHDTPDPSPLRGARHDSDTS 175 R + +S ++ G P R+ R + D S +RH SP D + Sbjct: 1416 RERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSP---GMKDIPRT 1472 Query: 176 PPRRIRHDSSDTSPPRRARHDSPDPSP--PRRPQHNSSGASPRRVR---HDSPDPSPPRR 230 P R D+SP +A +P P P P+ N+ +P+R R S D R Sbjct: 1473 PSRG--RSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVAR 1530 Query: 231 ARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPR--TKSG 288 G S + + P S + SD+ +A+ +P + + S P +KS Sbjct: 1531 TPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR 1590 Query: 289 KAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDC 348 +P R+ S +SP K+ + S +P PR +S G + +G Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSK--GRGPS 1648 Query: 349 QKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSP 408 + + S SSP H PP+ R + S S P Sbjct: 1649 PEGSSSTESSPEH------------------------------PPKSRTARRGSRSSPEP 1678 Query: 409 PRRSQPPGKK 418 +S+ P ++ Sbjct: 1679 KTKSRTPPRR 1688 Score = 48.5 bits (114), Expect = 2e-05 Identities = 64/246 (26%), Positives = 91/246 (36%), Gaps = 34/246 (13%) Query: 203 PRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSD-- 260 PR P S ++ D +P RR+R GSS + + S SR +L S Sbjct: 1411 PRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSP-----GLRDGSGTPSRHSLSGSSPG 1465 Query: 261 ------TQQLRRARHD-SPDLAPNVTYSLPRTKSGKAP-----------ERASSKTSPHW 302 T R+ D SP+ PR++S +P ER+ S++S Sbjct: 1466 MKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQ 1525 Query: 303 KESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHK 362 K + L S + D+ P Q +S + DS D + T + L Sbjct: 1526 KTVARTPLGQRSRSGSSQELDVKPSASPQERS------ESDSSPDSKAKTRTPLRQRSRS 1579 Query: 363 QSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHM 422 S DS S LSP R R SS PR R +S SD SP ++ P Sbjct: 1580 GSSPEVDSKSRLSP--RRSRSGSSPEVKDKPRAAPRAQSG-SDSSPEPKAPAPRALPRRS 1636 Query: 423 YSGAKT 428 SG+ + Sbjct: 1637 RSGSSS 1642 Score = 48.1 bits (113), Expect = 2e-05 Identities = 54/165 (32%), Positives = 66/165 (40%), Gaps = 10/165 (6%) Query: 115 SNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDT 174 + R R TP + RR R T + R+ R T + RR+R T SP+ R S T Sbjct: 1954 TRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRT---SPVTRRRSRSRT 2010 Query: 175 SPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHG 234 SP R R S T P R R S P PR+ S SP +R S + PR AR Sbjct: 2011 SPVTR-RRSRSRTPPAIRRRSRSRTPLLPRK---RSRSRSPLAIRRRSRSRT-PRTARGK 2065 Query: 235 SSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDS--PDLAPN 277 S SP + S S S T R S P +A N Sbjct: 2066 RSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALN 2110 Score = 41.6 bits (96), Expect = 0.002 Identities = 44/168 (26%), Positives = 59/168 (35%), Gaps = 25/168 (14%) Query: 124 PDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHD 183 P + R R P P+ RK R + S + + S + S +S Sbjct: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645 Query: 184 SSDTSPPRRARHDSPDPSPPRRP------------------QHNSSGASPRRVRHDSPDP 225 SS SP + P P+ P++P S SP R SP P Sbjct: 2646 SSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQP 2705 Query: 226 SPPRRARHGSSDISSPR--RVHNNSPDTSRRTLGSSDTQQLRRARHDS 271 S PR + SS+ S R R + SP RR +T R RH S Sbjct: 2706 S-PRDQQSSSSERGSRRGQRGDSRSPSHKRR----RETPSPRPMRHRS 2748 Score = 39.3 bits (90), Expect = 0.011 Identities = 40/177 (22%), Positives = 65/177 (36%), Gaps = 29/177 (16%) Query: 138 PSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDS 197 P R +P P+P+ A + P P +P +R R SS +S + S Sbjct: 2572 PEVALKRVPSPTPAPKEAVREGRPPEP----------TPAKRKRRSSSSSSSSSSSSSSS 2621 Query: 198 PDPSPPRRPQHNSSGASPRRVRHDSPDPSP-------------PRRARHGSSDISSPRRV 244 S +SS +S S PSP P++ G SPR+ Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP 2681 Query: 245 HNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPH 301 ++ D+ R+L S ++ R SP +P S + + +R S++ H Sbjct: 2682 IDSLRDS--RSLSYSPVER----RRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSH 2732 Score = 38.1 bits (87), Expect = 0.024 Identities = 74/351 (21%), Positives = 115/351 (32%), Gaps = 41/351 (11%) Query: 124 PDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDT---PDPSPLRGARHDSDTSPPRRI 180 P S+ RV T P + R TP +P ++R + P PS G PP + Sbjct: 2386 PLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD 2445 Query: 181 RHDSSDTSP-PRRARHDSPDPSPPRRPQHNSSGASPRRVR----HDS----PDPSPPRR- 230 + S S ++R +P Q SSGA H+ P P P Sbjct: 2446 QPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSD 2505 Query: 231 --ARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSG 288 S+ P + P RR+ SS + + S + + + S G Sbjct: 2506 VGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEG 2565 Query: 289 KA----PERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDS 344 + PE A + S PK + E P P K++ +S S Sbjct: 2566 SSLPVQPEVALKRVP--------SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSS 2617 Query: 345 KGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDS 404 ++ S SS S S S SP +P ++ SP + Sbjct: 2618 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKK---------- 2667 Query: 405 DLSPP--RRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFE 453 PP RRS+ P K + + +R + +DQ++ + E Sbjct: 2668 --PPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSE 2716 Score = 37.0 bits (84), Expect = 0.054 Identities = 81/361 (22%), Positives = 136/361 (37%), Gaps = 57/361 (15%) Query: 124 PDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHD 183 P++ PR+ G+ P P+ P PS L G++ P + + Sbjct: 981 PETPPRQSHSGSISPYPKVKAQTPPGPS-------------LSGSK---SPCPQEKSKDS 1024 Query: 184 SSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSP-- 241 + P + S P P + G S +++ S SP R SD SSP Sbjct: 1025 LVQSCPGSLSLCAGVKSSTP--PGESYFGVSSLQLKGQS-QTSPDHR-----SDTSSPEV 1076 Query: 242 RRVHNNSPDTSRRTLGSSDTQQLRRARHDSP--DLAPNVTYSLPRTKSGKAPERASSKTS 299 R+ H+ SP + S + + R+R SP +LA ++S +R S Sbjct: 1077 RQSHSESPSLQSK---SQTSPKGGRSRSSSPVTELA---------SRSPIRQDRGEFSAS 1124 Query: 300 PHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSP 359 P K SG S P+ S+++ D P + + +SK D ++ Sbjct: 1125 PMLK-SGMS----PEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATA- 1178 Query: 360 RHKQSPGHQDSDSDLSPPRNRPRHR--SSDSDLSPPRRRQRTKSS----DSDLSPPRRSQ 413 SP Q P ++RP D+ +PPR R SS + + + P SQ Sbjct: 1179 ----SPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQ 1234 Query: 414 PPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNL 473 S G +L+ + E +E+ + E+ E E + A ++ D+S + +L Sbjct: 1235 DEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSP-EVEERPAVSLTLDQSQSQASL 1293 Query: 474 K 474 + Sbjct: 1294 E 1294 Score = 34.7 bits (78), Expect = 0.27 Identities = 31/99 (31%), Positives = 38/99 (38%), Gaps = 16/99 (16%) Query: 124 PDSSPRRVRHGTPDP------SPRKDRHDTPDP-----SPRRARHDTPDPSPLRGARHDS 172 P + P+ P P SPRK D SP R +P PSP S Sbjct: 2656 PQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSS 2715 Query: 173 DTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSS 211 + R R DS SP + R ++P P P R H SS Sbjct: 2716 ERGSRRGQRGDSR--SPSHKRRRETPSPRPMR---HRSS 2749 Score = 33.1 bits (74), Expect = 0.78 Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 5/58 (8%) Query: 120 RHDTPDSSPRRVRHGTPDPSPRK-DRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSP 176 R +P SPR + + + R+ R D+ PS +R R +TP P P+ RH S SP Sbjct: 2699 RRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKR-RRETPSPRPM---RHRSSRSP 2752 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 75.9 bits (185), Expect = 1e-13 Identities = 93/319 (29%), Positives = 121/319 (37%), Gaps = 43/319 (13%) Query: 137 DPSPRKDRHDTPDPSPRRARHDTPDPSPLR-GARHDSDTSPPRRIRHDSSDTSPPRR--- 192 +PSP K+ + R R + S R +R S T P RR R S SP RR Sbjct: 258 EPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSP 317 Query: 193 ARHDSP-DPSPPRR----PQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRR--VH 245 R SP +PPRR P+H S + RR R S S + S S P++ Sbjct: 318 RRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKR 377 Query: 246 NNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLP------RTKSGK---APERASS 296 +SP R L S + RR R P P T P RT+ + +P R S Sbjct: 378 TSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSG 437 Query: 297 KTSPH-WKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSD 355 K + H E S PK K E K A + +++ + + Q ++DS Sbjct: 438 KVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSG 497 Query: 356 LSSPRHKQSP--------------GHQDSDSDLSPPRNR-----PRHRSSDSDLSPPRRR 396 SS + P H S S PR R PR R S PP RR Sbjct: 498 SSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRR 557 Query: 397 QRTKSSDSDLSPPRRSQPP 415 +R S S PPRR + P Sbjct: 558 RR---SPSPAPPPRRRRTP 573 Score = 73.6 bits (179), Expect = 5e-13 Identities = 99/395 (25%), Positives = 150/395 (37%), Gaps = 79/395 (20%) Query: 85 DERPEEVKQMEAFRSSAKWKLLGGHNEDLPSN----RHFRHDTPDSSPRRVRHGTPDPSP 140 + + E+ K+ RS ++ K PS+ R R + SPRR PSP Sbjct: 264 NSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSP 323 Query: 141 RK---DRHDTPDPSPRRARHDTPDPSPLRGARHDS------------------------- 172 R+ R P P RR+R SP+R R S Sbjct: 324 RRRTPPRRMPPPPRHRRSR------SPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKR 377 Query: 173 DTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRA- 231 +SPPR+ R S SPPRR SP +PP + +H+ + R R SP R + Sbjct: 378 TSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSG 437 Query: 232 ----------RHGSSDISSPRRVH-NNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTY 280 R S PR+V + S + + ++D+ Q RR Y Sbjct: 438 KVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRR------------QY 485 Query: 281 SLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISP-PRKKQAK-SHFGD 338 +S +SS K S + + ++ SP PRK+Q + S G Sbjct: 486 RRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGR 545 Query: 339 KKQLDSKGDC-QKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRS-SDSDLSPPRRR 396 +++ S ++ + S PR +++P SPP PR RS S SPP +R Sbjct: 546 RRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPP---PRRRSPSPRRYSPPIQR 602 Query: 397 QRTKS------SDSDLSPPRR----SQPPGKKAAH 421 + + S + S PP+R S PP ++ +H Sbjct: 603 RYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSH 637 Score = 70.9 bits (172), Expect = 3e-12 Identities = 86/354 (24%), Positives = 124/354 (35%), Gaps = 65/354 (18%) Query: 114 PSNRHFRHDTPDSSPRRVRHG-TPDPSPRK----------------------DRHDTPDP 150 P R R P + P + RH TP S R ++ ++P P Sbjct: 394 PPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSP 453 Query: 151 SPRRARHDTPDPSPLRGARHDSDTSPPRRIRH---------------DSSDTSPPR---- 191 +P+ + + + +G + + S +R ++ S D P R Sbjct: 454 APKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVK 513 Query: 192 -----RARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHN 246 R R SP S P+ SPR R SP P PP R R S PRR Sbjct: 514 NGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSP-PPTRRRRSPSPAPPPRRRRT 572 Query: 247 NSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLP---RTKSGKAPERASSKTSPHWK 303 +P RRT ++ R SP + + S P RT S P + + SP K Sbjct: 573 PTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPK 632 Query: 304 ESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQ 363 SH PK SP K+++ S ++ S + S + RH Sbjct: 633 RR-VSHSPPPKQRS-------SPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 684 Query: 364 SPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGK 417 SP + + SPP P R + S P+RRQ S + R+ P K Sbjct: 685 SPRPRAPQTSSSPP---PVRRGASSS---PQRRQSPSPSTRPIRRVSRTPEPKK 732 Score = 69.3 bits (168), Expect = 1e-11 Identities = 75/265 (28%), Positives = 105/265 (39%), Gaps = 30/265 (11%) Query: 120 RHDTPDSSPRR------------VRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRG 167 R TP PRR R +P P P++ P P RRA +P P P R Sbjct: 578 RRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRA---SPSPPPKRR 634 Query: 168 ARHD---SDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPD 224 H S P R S +S R+ S R PQ N + R R Sbjct: 635 VSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTS 694 Query: 225 PSPPRRARHGSSDISSPRRVHNNSPDTS--RRTLGSSDTQQLRRARHDSPDLAPNVTYSL 282 SPP R G+S SSP+R + SP T RR + + +++++A SP V+ S Sbjct: 695 SSPP-PVRRGAS--SSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSS- 750 Query: 283 PRTKSGKAPERASSK----TSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGD 338 R+ SG +PE A+ K SP +S +++ S K P SP + + G Sbjct: 751 -RSVSG-SPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGG 808 Query: 339 KKQLDSKGDCQKATDSDLSSPRHKQ 363 KK+ K K +HK+ Sbjct: 809 KKKKKKKDKKHKKDKKHKKHKKHKK 833 Score = 64.7 bits (156), Expect = 2e-10 Identities = 112/526 (21%), Positives = 192/526 (36%), Gaps = 104/526 (19%) Query: 79 VVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDP 138 + + F++ + EE+KQ R + KL +D ++ + + S +R R + P Sbjct: 119 IPSAFLELKKEEIKQ----RQIEQEKLASMKKQDEDKDKRDKEEKESSREKRER--SRSP 172 Query: 139 SPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSP 198 RK R PSPRR +SP RR R S SP R + SP Sbjct: 173 RRRKSR----SPSPRRR------------------SSPVRRERKRSHSRSPRHRTKSRSP 210 Query: 199 DPSPPRRP-----------------QHNSSGASPRRVRHDSP-----DPSPPRRARHGSS 236 P+P ++ Q +S + +V P +PSP + ++ Sbjct: 211 SPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKE 270 Query: 237 DISSPRRVHNNSPDTSR-RTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERAS 295 + R + S SR R+ S T+ RR R S +P P + +P R Sbjct: 271 KEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPR---RRPSPRRRPSPRR-- 325 Query: 296 SKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSD 355 +T P PPR ++++S ++ + + S Sbjct: 326 -RTPPRRMP--------------------PPPRHRRSRSPVRRRR----RSSASLSGSSS 360 Query: 356 LSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQR-----TKSSDSDLSP-P 409 SS +SP + SPPR + R SPPRRR R T + SP P Sbjct: 361 SSSSSRSRSPPKKPPKRTSSPPR---KTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTP 417 Query: 410 RRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGR 469 ++S K + G +G V E++E + + E +E DK G+ Sbjct: 418 QQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPR--KVELSESE---EDKGGK 472 Query: 470 KRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDE 529 + ++QRR+ + +++ + R ++ +V++ ++ R+ Sbjct: 473 M--AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRR---RHSPSR 527 Query: 530 DLDRMLREQEREGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNR 575 R++++E P + + + R R PAPPP R Sbjct: 528 SASPSPRKRQKETSPRG----RRRRSPSPPPTRRRRSPSPAPPPRR 569 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 73.9 bits (180), Expect = 4e-13 Identities = 113/556 (20%), Positives = 208/556 (37%), Gaps = 59/556 (10%) Query: 88 PEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRH-----DTP-----DSSPRRVRHGTPD 137 P+ + RS + K G H+ + S H R DT + R R D Sbjct: 382 PQRKQSPPRHRSPMREK--GRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQD 439 Query: 138 PSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDS 197 S +D D +P R R D D R R D R +R S DT R Sbjct: 440 QSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESR-----D 494 Query: 198 PDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDI---SSPRRVHNNSPDTSRR 254 P S R H+ R H D P +G + + SS + N S + SR Sbjct: 495 PRDSRSTRDAHDYRDREGRDT-HRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRS 553 Query: 255 TLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPK 314 + + ++ R+R P+L ++ + + S ++ ++ +S + S+P+ Sbjct: 554 EIRN---DRMGRSRGRVPELPEK------GSRGSRGSQIDSHSSNSNYHDSWETRSSYPE 604 Query: 315 NSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQ------ 368 +Y + R + G++ + D++ Q+ + R+ + + Sbjct: 605 RDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERR 664 Query: 369 -----DSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMY 423 D + + R+R R R + + R R R + + +L R + ++ Sbjct: 665 VDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERD 724 Query: 424 SGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRK 483 D RE++ +E+D+E E E + E + R+R + ER E+ R+ Sbjct: 725 RERDRD---RDHDRERERERERDREKER-EREREERERERERERERERERERER-ERARE 779 Query: 484 AEKDSERDELYAQWGKGLAQSRQQQQNVEDAMK-----EMQKPLARYIDD-----EDLDR 533 +K+ ER + KG R++++ + + + +K RY ++ + Sbjct: 780 RDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPK 839 Query: 534 MLREQEREGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGF 593 RE + D + KN+ ++ VRP+ S P + G RW DR Sbjct: 840 RRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQG-RWKEEDRKP-- 896 Query: 594 EQKRFARLASKKAVEE 609 E+K +R ++ ++E Sbjct: 897 ERKESSRRYEEQELKE 912 Score = 45.8 bits (107), Expect = 1e-04 Identities = 97/448 (21%), Positives = 156/448 (34%), Gaps = 66/448 (14%) Query: 130 RVRHGTPDPSPR-KDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTS 188 R HG PSPR K SP R D + ++ R D DT P +R +SS S Sbjct: 58 RFVHG---PSPRGKGYSSNYRRSPERPTGDLRER--MKNKRQDVDTEPQKRNTEESS--S 110 Query: 189 PPR----RARHDSPDP---SPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSP 241 P R R RH + + R P+ R DS + H S Sbjct: 111 PVRKESSRGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKR 170 Query: 242 RRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRT-KSGKAPERASS--KT 298 +++ + + +++ + SP++ + P KS K+P+R SS + Sbjct: 171 QKIQRELMKLEQENM--EKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSS 228 Query: 299 SPHWKESGASHLSFP-----KNSKYEYD-------PDISPPRK------KQAKSHFGDKK 340 S K+ S +S P +NSK P PP K+ K + K Sbjct: 229 SASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKD 288 Query: 341 QLDSKGDCQKATDSDLSSPRHKQ----------------SPGHQDSDSDL---------S 375 +++ K K D R K+ S H S S S Sbjct: 289 RIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPS 348 Query: 376 PPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDI 435 P R R S L+PP RR + LS P+R Q P + + M + T Sbjct: 349 PRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQ 408 Query: 436 QREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSE--RDEL 493 +++ + +D + E + R+ + +R + + +D+ RD Sbjct: 409 SHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRR 468 Query: 494 YAQWGKGLAQSRQQQQNVEDAMKEMQKP 521 + + + SR+ + D KE + P Sbjct: 469 ELRDSRDMRDSREMRDYSRDT-KESRDP 495 Score = 39.7 bits (91), Expect = 0.008 Identities = 48/243 (19%), Positives = 86/243 (35%), Gaps = 33/243 (13%) Query: 384 RSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELK 443 RS + R R + K D D P +R+ S DI+ ++ Sbjct: 76 RSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTP 135 Query: 444 EQDQETMAFEAE----------FQYAETVFRDKSGRKRNLKLERLEQRR--KAEKDSERD 491 E ++E + +E + Y + + +K +L +LEQ K E+ + Sbjct: 136 ESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKK 195 Query: 492 ELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKK 551 E+ + + + + K P + +D R+ P+ + ++ Sbjct: 196 EVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKD-----RKTSAVSSPLLD--QQ 248 Query: 552 NKAKENKNKKVRPRYSGPAPP-PNRFNIWPGYR-------------WDGVDRSNGFEQKR 597 +K N++KK PR P PP P + Y+ DG DR FE++R Sbjct: 249 RNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQR 308 Query: 598 FAR 600 R Sbjct: 309 EKR 311 Score = 34.7 bits (78), Expect = 0.27 Identities = 70/319 (21%), Positives = 114/319 (35%), Gaps = 38/319 (11%) Query: 186 DTSPPRRARHDSPDPSPPRRPQHNSS----GASPRRVRHDSPDPSPPRRARHGS--SDIS 239 DT+ + D PD + +H ++ G++P + P P P A + + ++ Sbjct: 1061 DTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLA 1120 Query: 240 SPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTS 299 + S TS T+ +S T P N T++ + R + Sbjct: 1121 ATTAAAATSFSTSAITISTSAT----------PTNTTNNTFANEDSHRKCHRTRVEKVET 1170 Query: 300 PHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSP 359 PH A H P + K S + +SH + + S ++ D D S Sbjct: 1171 PHVTIEDAQHRK-PMDQKRSS----SLGSNRSNRSHTSGRLRSPSNDSAHRSGD-DQSGR 1224 Query: 360 RHKQSPGHQDSDSDLSPPRNRPRHRSSDS-DLSPPRRRQRTKSSDSDLSPPRRSQPPGKK 418 + G +D + S R D P R + DS RRS P + Sbjct: 1225 KRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDR 1284 Query: 419 AAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFR--DKSGRK---RNL 473 H SG+ + L+E+D+ E E + +T R D+ K RN Sbjct: 1285 QVHSRSGSFD---------SRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNR 1335 Query: 474 KLERLEQR-RKAEKDSERD 491 +RL +R R+ E+D RD Sbjct: 1336 DRDRLRERERERERDKRRD 1354 Score = 33.1 bits (74), Expect = 0.78 Identities = 68/303 (22%), Positives = 102/303 (33%), Gaps = 55/303 (18%) Query: 123 TPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRH 182 TP S+P + P P P T P+ A S A S ++ P + Sbjct: 1089 TPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTN 1148 Query: 183 DSSDTSPPRRARH---------------DSPDPSPPRRPQHNSSGASPRRVRHDSPD-PS 226 ++ R H D+ P + + +S G++ H S S Sbjct: 1149 NTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRS 1208 Query: 227 PPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTK 286 P + H S D S R+ +S R S + R++R D + K Sbjct: 1209 PSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRID-------------QLK 1255 Query: 287 SGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKG 346 G+ P R++S ++ SH S SP +Q S G DS+ Sbjct: 1256 RGE-PSRSTSSD----RQDSRSHSSRRS----------SPESDRQVHSRSGS---FDSRD 1297 Query: 347 DCQKAT----DSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSS 402 Q+ D + R D D+D PRNR R R + + R R+R K Sbjct: 1298 RLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERE----RERERDKRR 1353 Query: 403 DSD 405 D D Sbjct: 1354 DLD 1356 Score = 30.8 bits (68), Expect = 3.9 Identities = 71/348 (20%), Positives = 118/348 (33%), Gaps = 37/348 (10%) Query: 29 ESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTAISTTKLEKEEEEDDGDLPVVAEFVDERP 88 E R+R ++R K R D + + E+E E ++ + E ER Sbjct: 710 ERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERE 769 Query: 89 EEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDS--SPRRVRHGTPDPSPRKDRHD 146 E ++ E R K + ED R R + + R R G + +K + Sbjct: 770 RE-RERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRN 828 Query: 147 TPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRP 206 PSPR+ SP R H D+ D+ ++ + +H S RP Sbjct: 829 EGSPSPRQ--------SPKRRREHSPDS--------DAYNSGDDKNEKHRLL--SQVVRP 870 Query: 207 QHNSSGASPRRVRHD-----SPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDT 261 Q + S SP + D + P R + +S D R ++ Sbjct: 871 QESRS-LSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILES 929 Query: 262 QQLRR----ARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSK 317 ++R H S D + K K ++ K + G + S+ Sbjct: 930 SRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKED--DVGIERGNIETTSE 987 Query: 318 YEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSP 365 D + P+K Q K +KK+ SKGD + + + K+ P Sbjct: 988 ---DGQVFSPKKGQKKKSI-EKKRKKSKGDSDISDEEAAQQSKKKRGP 1031 >gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sapiens] Length = 2365 Score = 68.2 bits (165), Expect = 2e-11 Identities = 83/321 (25%), Positives = 124/321 (38%), Gaps = 31/321 (9%) Query: 112 DLPSNRHFRHDTPD-SSPRRVRHGTPDPS------PRKDRHDTPDPSPRR------ARHD 158 D P + D P SSP R P S PR R +P+ + R A+ D Sbjct: 426 DNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRD 485 Query: 159 TPDPS-PLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRR 217 P S P R R + TS +R +S TS P RA D+P S +R N +SP R Sbjct: 486 NPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRD--NPRASSPNR 543 Query: 218 VRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSP--DLA 275 D+P S +R +S SSP R ++P TS + RA D+P A Sbjct: 544 AARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCA 603 Query: 276 PNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSH 335 RT S R + +TS +++ S P + + P S R+ ++ Sbjct: 604 QRDNPRASRTSSPNRATRDNPRTSCAQRDN--PRASSPNRTTQQDSPRTSCARRDDPRAS 661 Query: 336 FGDK--KQLDSKGDCQKATDSDLSSPRH-------KQSPGHQDSDSDLSPPRNRPRH--R 384 ++ +Q + + C + SSP + S +D SP R + R Sbjct: 662 SPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPR 721 Query: 385 SSDSDLSPPRRRQRTKSSDSD 405 +S + PR R ++ D Sbjct: 722 TSCARRDNPRASSRNRTIQRD 742 Score = 57.0 bits (136), Expect = 5e-08 Identities = 75/320 (23%), Positives = 112/320 (35%), Gaps = 33/320 (10%) Query: 120 RHDTPDSSPRRVRHGTPDPSPRKD--RHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPP 177 R D SSP R T +PR R D P S R +P R + S P Sbjct: 703 RDDPRASSPNRT---TQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSP 759 Query: 178 RRI-----------RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASP-RRVRHDSPDP 225 R R D+ TS P RA D+P S +R N +SP R + D+P Sbjct: 760 NRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQR--DNLRASSPIRATQQDNPRT 817 Query: 226 SPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRT 285 + SS + D R T D Q + D+P + + + Sbjct: 818 CIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKEN 877 Query: 286 KSGKAPERASS-----KTSPHWKESGASHLSFPKNSKYEYDP-DISPPRKKQAKSHFGDK 339 +P R++ +SPH SFP P SP R KQ++ + Sbjct: 878 LRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASI 937 Query: 340 KQLDSKGDCQKATD----SDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRR 395 ++GD + + + P+ P + S + + P H+S+ SP Sbjct: 938 ALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSP--- 994 Query: 396 RQRTKSSDSDLSPPRRSQPP 415 + + L+ P SQPP Sbjct: 995 -VYPAAYGAPLTSPEPSQPP 1013 Score = 47.8 bits (112), Expect = 3e-05 Identities = 117/543 (21%), Positives = 181/543 (33%), Gaps = 90/543 (16%) Query: 88 PEEVKQMEA-FRSSAKWKLLGGHNEDLPSNRHFRHDTPDSS--------PRRVRHGTPDP 138 P KQ E + S A G + +R +HD P SS P R + +P Sbjct: 924 PSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNP 983 Query: 139 SPRK-DRHDTPD-PSPRRARHDTPDPSPLRGA----RHDSD--TSPPRRIRHDSSDTSP- 189 + R +P P+ A +P+PS A D+ +SPPR ++HD P Sbjct: 984 GHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPE 1043 Query: 190 PRRARHDSPDPSPPRRPQ-----HNSSGASPRRVRHDSPDPSP----PRRARHGSSDISS 240 PR + P PP P H + + RH DP P A H S Sbjct: 1044 PRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEH---QCQS 1100 Query: 241 PRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTY-SLPRTKS-GKAPERASSKT 298 P+ H + +G D + +P+ P++ + LPR + P S Sbjct: 1101 PQ--HEPLQLPAPVCIGYRDAPRASSPPRQAPE--PSLLFQDLPRASTESLVPSMDSLHE 1156 Query: 299 SPHWKESGA-SHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDS--- 354 PH H P S SPPR+ S F S +TDS Sbjct: 1157 CPHIPTPVCIGHRDAPSFS--------SPPRQAPEPSLFFQDPPGTSMESLAPSTDSLHG 1208 Query: 355 -----------DLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSD 403 +PR P H SD P P +PP + + Sbjct: 1209 SPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLERE 1268 Query: 404 -----SDLSPPRR--SQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEF 456 +DL PPRR + PG +A G +++R + + + + AF+A+ Sbjct: 1269 EYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQ- 1327 Query: 457 QYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMK 516 GR + + + R+ + ++ K +R+ Q Sbjct: 1328 ---------DEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWS 1378 Query: 517 EMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRF 576 ++P + DR L +G P+ + E + + RP SG A P Sbjct: 1379 PEKRP--------EGDRQL-----QGSPLPPRTSA-RTPERELRTQRPLESGQAGPRQPL 1424 Query: 577 NIW 579 +W Sbjct: 1425 GVW 1427 Score = 40.0 bits (92), Expect = 0.006 Identities = 97/439 (22%), Positives = 153/439 (34%), Gaps = 47/439 (10%) Query: 6 PLSKAEYLKRYLSGADAGVDRGSESGRKRRKKR----PKPGGAGGKGMRIVD-DDVSWTA 60 P + + L SG + VD G G KR P+ G R + + V + Sbjct: 57 PPAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLE 116 Query: 61 ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120 TT L ED G P + P++ SS W + E+ PS Sbjct: 117 GLTTSLCGSCNEDPGSDPTSSPD-SATPDDTSNS----SSVDWDTVERQEEEAPS----W 167 Query: 121 HDTPDSSPRRVRHGT-PDPSPRKDRHDTPDP----SPRRARHDTPDPSPLRGA-----RH 170 + PRR R G D S R T P + + + DT G R Sbjct: 168 DELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRG 227 Query: 171 DSDTSPPRR--IRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRV-RHDSPDPSP 227 +S S R +S +P R + SP +R + AS R + R SP Sbjct: 228 ESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRD--TAQAASTREIPRASSPHRIT 285 Query: 228 PRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKS 287 R SS R + +TSR + DT + + D+P A + ++ PR S Sbjct: 286 QRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPR-ASSTQWNTPRASS 344 Query: 288 GKAPERASSKTSPHWKESGASH--LSFPKNSKYEYDPDI-----------SPPRKKQAKS 334 P R++ +P + + SFP + +P SP R Q ++ Sbjct: 345 ---PSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQREN 401 Query: 335 HFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPR-NRPRHRSSDSDLSPP 393 Q D+ + ++ + + + S +D+ SP R R +S + P Sbjct: 402 SRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNP 461 Query: 394 RRRQRTKSSDSDLSPPRRS 412 R + + + + PR S Sbjct: 462 RASRTSSPNRATRDNPRTS 480 >gi|153251865 hypothetical protein LOC84226 [Homo sapiens] Length = 1984 Score = 67.8 bits (164), Expect = 3e-11 Identities = 90/345 (26%), Positives = 127/345 (36%), Gaps = 53/345 (15%) Query: 119 FRHDTPDSSPRRVRHGTP-----DPSPRKDR------HDTPDP----SPRRARHDTPDPS 163 +R TP R RH PS R R H +P SP R H +P Sbjct: 1545 YRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSER 1604 Query: 164 PLRGARHDSDTSPPRRIRHDSSDT---SP-------PRRARHDSPDPSPPRRPQHNSSGA 213 R + SPP R H S+ SP P + RH SP R P S + Sbjct: 1605 SWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRS 1664 Query: 214 SPRRVRHDSPDPSPPRRARHGSSDIS--SPRRVHNNSPDTSRRTLGSSDTQQLRRARHDS 271 S R RH SP +R+ G S+ S SP + SP + R G S+ RH S Sbjct: 1665 SSER-RHRSPS----QRSHRGPSERSHCSPSERRHRSP-SQRSHRGPSE------RRHHS 1712 Query: 272 PDLAPNVTYSLPRTKSGKAPERAS----SKTSPHWKESGASHLSFPKNSKYEYDPDISPP 327 P ++ P +S ++P S S+ S H H ++ + P Sbjct: 1713 PS---KRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSP 1769 Query: 328 RKKQAKSHFGDKKQLDSKGDCQKATDSDLSSP--RHKQSPGHQDSDSDLS----PPRNRP 381 +++ +S + S+ ++ SP R + SP + S L P R Sbjct: 1770 SERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERR 1829 Query: 382 RHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQ-PPGKKAAHMYSG 425 HRS + R + S S LSP RS+ P ++ H SG Sbjct: 1830 SHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSG 1874 Score = 61.6 bits (148), Expect = 2e-09 Identities = 85/321 (26%), Positives = 116/321 (36%), Gaps = 40/321 (12%) Query: 115 SNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDP----SPRRARHDTPDPSPLRGARH 170 S+ RH +P R SP + RH +P P RH +P R Sbjct: 1664 SSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPAR 1723 Query: 171 DSDTSPPRRIRHDSSDTS--PPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPP 228 S SP R H S+ S P RH SP P S SP RH SP Sbjct: 1724 RSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSH-CSPSERRHRSPS---- 1778 Query: 229 RRARHGSSDIS--SPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTK 286 R H S+ S SP ++SP RR L R+RH L S + Sbjct: 1779 ERRHHSPSEKSHHSPSERSHHSPSERRR------HSPLERSRH---SLLERSHRSPSERR 1829 Query: 287 SGKAPERASSKTSPH-WKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSK 345 S ++ ER+ + S S SHLS + S+ SP + + H K S Sbjct: 1830 SHRSFERSHRRISERSHSPSEKSHLSPLERSR------CSP---SERRGHSSSGKTCHSP 1880 Query: 346 GDCQKATDSDLSSPRHKQSPGHQDS--DSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSD 403 + + S + R + H+ S + SP RP S + SP R +R Sbjct: 1881 SERSHRSPSGMRQGRTSER-SHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRR----- 1934 Query: 404 SDLSPPRRSQPPGKKAAHMYS 424 S L + PG++ +H S Sbjct: 1935 SPLKEGLKYSFPGERPSHSLS 1955 Score = 54.7 bits (130), Expect = 2e-07 Identities = 59/240 (24%), Positives = 79/240 (32%), Gaps = 28/240 (11%) Query: 88 PEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDT 147 P E + + S + H + H + SP RH +P + Sbjct: 1705 PSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSER 1764 Query: 148 PDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDT---SPPRRARH---DSPDPS 201 SP RH +P S SP R H S+ SP R+RH + S Sbjct: 1765 SHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRS 1824 Query: 202 PPRRPQHNSSGASPRRVRHDSPDP--------------SPPRRARHGSS--DISSPRRVH 245 P R H S S RR+ S P SP R H SS SP Sbjct: 1825 PSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERS 1884 Query: 246 NNSPDTSR--RTLGSSDTQQLRRARHDSPDLAP----NVTYSLPRTKSGKAPERASSKTS 299 + SP R RT S R RH ++ P + P +S ++P + K S Sbjct: 1885 HRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYS 1944 >gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] Length = 715 Score = 65.5 bits (158), Expect = 1e-10 Identities = 91/432 (21%), Positives = 157/432 (36%), Gaps = 34/432 (7%) Query: 123 TPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRH 182 TP S + R G PR + D PR + P G S+ + Sbjct: 160 TPTSQQKGSR-GKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAK 218 Query: 183 DSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPR 242 + T P + + D+P PS R+ + P R + SP R + + S Sbjct: 219 CQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRP 278 Query: 243 RVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERA-SSKTSPH 301 + H+ S R GS Q+ +R S N + + RT+ G + S++ H Sbjct: 279 QSHSQSRSPRRSRSGS---QKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSH 335 Query: 302 WKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRH 361 K + P+ + ++ +P +++ K+ D +G +S S Sbjct: 336 SKGKSQNQSRTPRRGR-SHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRS---Q 391 Query: 362 KQSPGHQ-DSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPR---------R 411 SP Q D SP + R R RS + R R R+ + D S R R Sbjct: 392 SGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSR 451 Query: 412 SQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKR 471 S+ P K H S +++ D R + KE+D + + +++ R+ Sbjct: 452 SRSPNKARDH--SRSRSPNKARDRSRSRSPSKERDHSQLGSPS---------KERDHRRS 500 Query: 472 NLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDL 531 + + R+ ERD + + ++ RQ++Q+ KE + +R +E Sbjct: 501 RSPSKERQCRQSRSSSKERDH---RRSRSPSKERQRRQS-RSPNKERDRSQSRSPSEERE 556 Query: 532 DRMLREQEREGD 543 R R +E D Sbjct: 557 HRQSRSPSKERD 568 Score = 62.8 bits (151), Expect = 9e-10 Identities = 82/338 (24%), Positives = 130/338 (38%), Gaps = 39/338 (11%) Query: 98 RSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARH 157 R S+ + G ++ N+ H SP + R + SP K R + SP +AR Sbjct: 378 RGSSSPRKESGRSQSGSPNKQRDHSR-SRSPNKARDRSRSRSPYKARDRSRSRSPNKARD 436 Query: 158 DTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGA-SPR 216 + SP + AR S + P + R D S + P +AR S SP + H+ G+ S Sbjct: 437 CSRSRSPYK-ARDRSRSRSPNKAR-DHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKE 494 Query: 217 RVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAP 276 R S PS R+ R S SS R H RR+ S +Q R++R +P Sbjct: 495 RDHRRSRSPSKERQCRQSRS--SSKERDH-------RRSRSPSKERQRRQSR------SP 539 Query: 277 NVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHF 336 N K +R+ S++ +E S + + + SP ++++ + Sbjct: 540 N-----------KERDRSQSRSPSEEREHRQSRSPSKERDRRRWR---SPSKERERRQSR 585 Query: 337 GDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRR 396 ++ D S S PR S N + R+S + S P + Sbjct: 586 SSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKE-SDPSQS 644 Query: 397 QRTKSSDSDLSPPRRS-----QPPGKKAAHMYSGAKTG 429 +S D SP R S + P K ++H S +G Sbjct: 645 TVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSG 682 Score = 60.5 bits (145), Expect = 5e-09 Identities = 91/406 (22%), Positives = 150/406 (36%), Gaps = 46/406 (11%) Query: 108 GHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRG 167 G + S+ + +PRR R +P K+R + S + R SP + Sbjct: 327 GRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKE 386 Query: 168 ARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSP 227 + SP + + D S + P +AR S S P + + S SP + R S SP Sbjct: 387 SGRSQSGSPNK--QRDHSRSRSPNKARDRSRSRS-PYKARDRSRSRSPNKARDCSRSRSP 443 Query: 228 PRRARHGSSDISSPRRVH--NNSPDTSR-RTLGSSDTQQLRRARHDSPDLAPNVTYSLPR 284 + S + R H + SP+ +R R+ S +++ ++ SP + S Sbjct: 444 YKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSP 503 Query: 285 TKSGKAPE-RASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLD 343 +K + + R+SSK H + SP +++Q + K+ D Sbjct: 504 SKERQCRQSRSSSKERDHRRSR-------------------SPSKERQRRQSRSPNKERD 544 Query: 344 SKGDCQKATDSDLSSPRHKQSPG-HQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSS 402 Q + S+ R +SP +D SP + R R +S S R R+ + Sbjct: 545 RS---QSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNK 601 Query: 403 DSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETV 462 S S PR S K+ AH S ++T + + + KE D TV Sbjct: 602 QSGYSRPRAS---SKEKAH--SRSRTPSKEGNHSQSRTSSKESDPS----------QSTV 646 Query: 463 FRDKSGRKRNLKLERLEQRRKAEKDSERD-ELYAQWGKGLAQSRQQ 507 R ++ + L Q R K S + G+ L+Q Q Sbjct: 647 PRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQ 692 Score = 58.9 bits (141), Expect = 1e-08 Identities = 71/281 (25%), Positives = 100/281 (35%), Gaps = 19/281 (6%) Query: 127 SPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSD 186 SP + R + SP K R + SP +AR + SP + SP + H Sbjct: 430 SPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLG 489 Query: 187 TSPPRRARHDSPDPSPPRRPQHNSSGA---------SPRRVRHDSPDPSPPRRARHGSSD 237 + R S PS R+ + + S + SP + R SP + S Sbjct: 490 SPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSR 549 Query: 238 ISSPRRVHNNSPDTS----RRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPER 293 S R H S S RR S ++ RR S + + P +SG + R Sbjct: 550 SPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPR 609 Query: 294 ASSKTSPHWKE---SGASHLSFPKNSKYEYDPDISP-PRKKQAKSHFGDKKQLDSKGDCQ 349 ASSK H + S + S + S E DP S PR K L Sbjct: 610 ASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPS 669 Query: 350 KATDSDLSS-PRHKQSPGHQDSDSDLSPPR-NRPRHRSSDS 388 K + S+ P Q+ DS +D + + P RSS S Sbjct: 670 KTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSS 710 Score = 53.5 bits (127), Expect = 6e-07 Identities = 71/288 (24%), Positives = 110/288 (38%), Gaps = 27/288 (9%) Query: 92 KQMEAFRSSAKWKLLGGHNEDLPSNR--HFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPD 149 K + RS + +K P+ H R +P+ + R R + PS +D Sbjct: 433 KARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSR--SRSPSKERDHSQLGS 490 Query: 150 PSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDP--------S 201 PS R + PS R R +S R R S + +R + SP+ S Sbjct: 491 PSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRS 550 Query: 202 PPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGS--- 258 P +H S SP + R SP + S SS R H+ S ++++ S Sbjct: 551 PSEEREHRQS-RSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPR 609 Query: 259 SDTQQLRRARHDSPDLAPNVTYSLPRTKSGKA-PERASSKTSPHWKESGASHLSFPKNSK 317 + +++ +R +P N +S RT S ++ P +++ SP WK S S +N Sbjct: 610 ASSKEKAHSRSRTPSKEGN--HSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRT 667 Query: 318 YEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQ-KATDSDLSSPRHKQS 364 SP S F Q S+ D Q AT S + P + S Sbjct: 668 PSKTSSHSP-------STFPSGGQTLSQDDSQADATTSKATLPGERSS 708 Score = 45.4 bits (106), Expect = 2e-04 Identities = 75/318 (23%), Positives = 107/318 (33%), Gaps = 42/318 (13%) Query: 126 SSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSS 185 SSP+R + +P T DP P + T +P R + + SS Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61 Query: 186 DTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVH 245 S + +P P R + S +P RV D+ R + +S R H Sbjct: 62 SKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDT---------RTSKASKASDVRCH 112 Query: 246 NNSPDTSR-RTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKE 304 SR RT G ++ +R SP A T RT G P AS +P ++ Sbjct: 113 QRRGTHSRGRTPGRRGSRSSKR----SPSRAS--TPGRIRT-HGARPGMASRVRTPTSQQ 165 Query: 305 SGASHLSFPKNSKYEYDPDISPPRKKQAKSH-------FGDKKQL---DSKGDCQKATDS 354 G+ S+ + + S PR KS+ G +L S CQ T Sbjct: 166 KGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPT-- 223 Query: 355 DLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKS-----------SD 403 P ++S S S + S + SP R KS S Sbjct: 224 --GIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSH 281 Query: 404 SDLSPPRRSQPPGKKAAH 421 S PRRS+ +K H Sbjct: 282 SQSRSPRRSRSGSQKRTH 299 >gi|217330641 IWS1 homolog [Homo sapiens] Length = 819 Score = 63.5 bits (153), Expect = 5e-10 Identities = 100/468 (21%), Positives = 174/468 (37%), Gaps = 54/468 (11%) Query: 107 GGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKD-----RH--DTPDPSPRRARHDT 159 G ED + +H DT RH + S R+D H D+ + P Sbjct: 26 GSDGEDDVNEQHSGSDTGSVE----RHSENETSDREDGLPKGHHVTDSENDEPLNLNASD 81 Query: 160 PDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVR 219 + L + DSD+ R +SD+ +H S S R S + + Sbjct: 82 SESEELHRQK-DSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLN 140 Query: 220 HDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVT 279 + D +H +SD + + + S+T+ + P ++ + + Sbjct: 141 GHASDSENEDVGKHPASD--------SEIEELQKSPASDSETEDALK-----PQISDSES 187 Query: 280 YSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDK 339 PR ++ + K P +S + L P+ S E + PPR + + S + Sbjct: 188 EEPPRHQASDSENEEPPK--PRMSDSESEELPKPQVSDSESE---EPPRHQASDS---EN 239 Query: 340 KQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRT 399 ++L + +DS+ P P HQ SDS+ P+ R SDS+ P R Q + Sbjct: 240 EELPK----PRISDSESEDP-----PRHQASDSE---NEELPKPRISDSESEDPPRNQAS 287 Query: 400 KSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELK---EQDQETMAFEAEF 456 S + +L PR S ++ G + D R +Q+ + + D+E + E Sbjct: 288 DSENEELPKPRVSD---SESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEM 344 Query: 457 QYAETVFRDKSGRKRNLKLERLEQRRKAEK-DSERDELYAQWGKGLAQSRQQQQNVEDAM 515 Q RK+ + E+ K +K DS+ DE + K + + ED Sbjct: 345 QNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEE 404 Query: 516 KEMQKP--LARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKK 561 K K + DD D D + + + +A+ ++ KE +KK Sbjct: 405 KASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKK 452 Score = 50.8 bits (120), Expect = 4e-06 Identities = 93/484 (19%), Positives = 167/484 (34%), Gaps = 61/484 (12%) Query: 70 EEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPR 129 E ED G P ++E + + K ++ +E+ P RH D+ + P Sbjct: 147 ENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPP--RHQASDSENEEPP 204 Query: 130 RVRHGTPD----PSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSS 185 + R + P P+ ++ +P +A + P PPR DS Sbjct: 205 KPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSE 264 Query: 186 DTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVH 245 + P+ DS PPR +S + R + P++ S+ R H Sbjct: 265 NEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASR-H 323 Query: 246 NNSP---DTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHW 302 P D S R DT+ + H + +S + S+ H Sbjct: 324 KQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHS------------SDSEEEEHK 371 Query: 303 KESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHK 362 K+ S + E + + RK S D+++ +K + +D+D Sbjct: 372 KQKMDS-----DEDEKEGEEEKVAKRKAAVLSDSEDEEKASAK-KSRVVSDAD------- 418 Query: 363 QSPGHQDSDSDLSPPRNRPRHR--SSDSDLSPPRRRQRTKSSDSDL--SPPRRSQPPGKK 418 DSDSD ++ R + +SDS+ + K+ + DL S Sbjct: 419 ------DSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENL 472 Query: 419 AAHMY--SGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLE 476 A ++ SG + T Q++L+E+ ET EAE ++ + E Sbjct: 473 IADIFGESGDEEEEEFTGF--NQEDLEEEKGETQVKEAEDSDSDDNIKRGKHMDFLSDFE 530 Query: 477 RLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLR 536 + QR+K+ R ++R + DA + + + + + DR L Sbjct: 531 MMLQRKKSMSGKRR------------RNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLN 578 Query: 537 EQER 540 Q++ Sbjct: 579 NQKK 582 >gi|158854042 hypothetical protein LOC222183 [Homo sapiens] Length = 653 Score = 62.0 bits (149), Expect = 2e-09 Identities = 89/392 (22%), Positives = 128/392 (32%), Gaps = 37/392 (9%) Query: 25 DRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTAISTTKLEKEEEEDDGDLPVVAEFV 84 D G ++G +R P +GG G W + + G P A Sbjct: 284 DEGRKTGSQRSSGSRSPSPSGGSG---------WGSPQRNGGSGQRSGAHGGRPGSAHSP 334 Query: 85 DERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPR--RVRHGTPDPSPRK 142 ++P +++A ++ PS R P S R R G R+ Sbjct: 335 PDKPSSPSPRVRDKAAAAAPTPPARGKESPSPR----SAPSSQGRGGRAAGGAGRRRRRR 390 Query: 143 DRHDTPDPS---PRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPD 199 R S PRR P P+P RG+ + SSD+ R A P+ Sbjct: 391 RRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRA------RSSSDSGSGRGAPGPGPE 444 Query: 200 PSPPRRPQHNSSGAS--PRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLG 257 P R + A P R R S PSP R G + S R SP R+ Sbjct: 445 PGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSR----SPGPHPRSWS 500 Query: 258 SSDTQQLRRARH-----DSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSF 312 SS + R+R SP +P+ L R K G+ R S + + S+ Sbjct: 501 SSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSY--S 558 Query: 313 PKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDS 372 P + P PR+ + S SD S+ H +SP S Sbjct: 559 PIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHG 618 Query: 373 DLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDS 404 S + R R+ +P SS+S Sbjct: 619 SYSSRSHGTRSRTRSPSRTPSPSYHSRSSSES 650 Score = 56.2 bits (134), Expect = 9e-08 Identities = 87/396 (21%), Positives = 140/396 (35%), Gaps = 62/396 (15%) Query: 58 WTAISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNR 117 W++ S + K++++ G R + +++E+ S L + + +R Sbjct: 159 WSSSSASPPPKKKKKKKGG--------HRRSRKKRRLESECSCGSSSPLRKKKKSVKKHR 210 Query: 118 HFRHDTPDSSPRRVRHGTP-----DPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDS 172 R D+ RR R + + + K R T P R RH + + H S Sbjct: 211 RDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYS 270 Query: 173 DTSPPRRI----RHDSSDTSPPRRARHDSPDPS------PPRR----------------- 205 D+ P R+ R + T R + SP PS P+R Sbjct: 271 DSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGS 330 Query: 206 ---PQHNSSGASPR-RVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDT 261 P S SPR R + + P+PP R + S S+P +S R G + Sbjct: 331 AHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAP-----SSQGRGGRAAGGAGR 385 Query: 262 QQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYD 321 ++ RR R + + R + AP R SS++ + S S + + Sbjct: 386 RRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDS-----GSGRGAPG 440 Query: 322 PDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRP 381 P P + H G K+ + + + S H + G + S SP P Sbjct: 441 PG---PEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSP---GP 494 Query: 382 RHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGK 417 RS S SP + R R S++ P RS P K Sbjct: 495 HPRSWSSSRSPSKSRSR--SAEKRPHSPSRSPSPKK 528 Score = 32.7 bits (73), Expect = 1.0 Identities = 37/149 (24%), Positives = 47/149 (31%), Gaps = 36/149 (24%) Query: 301 HWKESGASHLSFPKNSKYEYDPDISPPRKKQAKS--HFGDKKQLDSKGDCQKATDSDLSS 358 HW S AS PP+KK+ K H +K+ + +C + S L Sbjct: 158 HWSSSSAS----------------PPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRK 201 Query: 359 PRHKQSPGHQDSDSDLSPPRNRPRHRSSD------------SDLSPPRRRQRTKSSDSDL 406 + +D S + R R RSS P RR SS S Sbjct: 202 KKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSH 261 Query: 407 SPPRRS------QPPGKKAAHMYSGAKTG 429 SP S P H G KTG Sbjct: 262 SPSLSSHYSDSRSPSRLSPKHRDEGRKTG 290 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 59.3 bits (142), Expect = 1e-08 Identities = 84/363 (23%), Positives = 129/363 (35%), Gaps = 13/363 (3%) Query: 53 DDDVSWTAISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNED 112 D S ++ S+ + + D D ++ D + + K E+ S + K ++ Sbjct: 589 DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS-ESDSSDSDSK-----SDS 642 Query: 113 LPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDS 172 SN D DSS + D S D D+ S D+ D S + S Sbjct: 643 SDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS 702 Query: 173 DTSPPRRI-RHDSSDTSPPRRARHDSPDPSPPRRPQHNS--SGASPRRVRHDSPDPSPPR 229 D+S DSSD+S + DS + S ++S S +S DS D S Sbjct: 703 DSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 762 Query: 230 RARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGK 289 + S S +++ S + SSD+ + S + + + S + S Sbjct: 763 NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN--SSDSSDSSDSSDSDS 820 Query: 290 APERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQ 349 + SS +S S +S S +S D D S S D + D Sbjct: 821 SNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS 880 Query: 350 KATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPP 409 ++DS+ SS S SDSD S N SSDS S S +S+ S Sbjct: 881 DSSDSNESSNSSDSSDSSNSSDSDSSDSSN--SSDSSDSSNSSDSSESSNSSDNSNSSDS 938 Query: 410 RRS 412 S Sbjct: 939 SNS 941 Score = 55.5 bits (132), Expect = 1e-07 Identities = 73/292 (25%), Positives = 105/292 (35%), Gaps = 22/292 (7%) Query: 122 DTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIR 181 D+ DSS + D S D D+ D S D+ D S + + SD++ Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN------ 786 Query: 182 HDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSP 241 DSS++S DS D S NSS +S DS D S + S SS Sbjct: 787 -DSSNSS-------DSSDSS-------NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831 Query: 242 RRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPH 301 +NS D+S + S + R DS + + + S S + S+++S Sbjct: 832 SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS 891 Query: 302 WKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRH 361 S +S+ S +S D S S + + D ++DS SS Sbjct: 892 SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951 Query: 362 KQSPGHQDSD-SDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRS 412 S SD S+ S + SSDS S S SD S S Sbjct: 952 NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003 Score = 53.9 bits (128), Expect = 4e-07 Identities = 68/299 (22%), Positives = 108/299 (36%), Gaps = 17/299 (5%) Query: 115 SNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARH--DTPDPSPLRGARHDS 172 SN +D+ +SS + D S D D+ D S + + D+ + S + + S Sbjct: 780 SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839 Query: 173 DTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRAR 232 D+S DSSD S + S +SS +S DS + S + Sbjct: 840 DSSDSS----DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS 895 Query: 233 HGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPE 292 S+ S +NS D+S + S ++ + + + + N + S + S + + Sbjct: 896 DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 955 Query: 293 RASSKTSPHWKESGASHLSFPKNSKYEYD----PDISPPRKKQAKSHFGDKKQLDSKGDC 348 ++S S + +S S+ S +S D D S S+ D D Sbjct: 956 SSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015 Query: 349 QKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLS 407 ++DS SS S SDS S SSDS S S SD S Sbjct: 1016 SNSSDSSNSSDSSNSSDSSDSSDSSDSSD-------SSDSSDSSDSSNSSDSSDSSDSS 1067 Score = 51.6 bits (122), Expect = 2e-06 Identities = 72/304 (23%), Positives = 105/304 (34%), Gaps = 17/304 (5%) Query: 115 SNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGA------ 168 SN D+ DSS + D S D D+ D S D+ D S + Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS 719 Query: 169 ---RHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDP 225 DSD+S DSSD+S + DS D S +SS +S DS D Sbjct: 720 NSNSSDSDSSN----SSDSSDSSNSSDS-SDSSD-SSNSSDSSDSSDSSNSSDSSDSSDS 773 Query: 226 SPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRT 285 S + + S S ++ S + SSD+ + + + + S + Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833 Query: 286 KSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYD-PDISPPRKKQAKSHFGDKKQLDS 344 S + + + S S +S +S+ S NS D D S S + Sbjct: 834 DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893 Query: 345 KGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRN-RPRHRSSDSDLSPPRRRQRTKSSD 403 D ++DSD S + + SD S N SSDS S S+ Sbjct: 894 SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953 Query: 404 SDLS 407 SD S Sbjct: 954 SDSS 957 Score = 51.6 bits (122), Expect = 2e-06 Identities = 75/297 (25%), Positives = 100/297 (33%), Gaps = 32/297 (10%) Query: 110 NEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGAR 169 N SN D+ DSS D S D D+ D S D+ D S + Sbjct: 1023 NSSDSSNSSDSSDSSDSS---------DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073 Query: 170 HDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPR 229 SD+S DSS++S DS D S NSS +S DS D S Sbjct: 1074 DSSDSS-------DSSESS-------DSSDSS-------NSSDSSDSSDSSDSSDSSDSS 1112 Query: 230 RARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGK 289 + S +S ++ S + SSD+ + DS D + + S S Sbjct: 1113 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES-SDSSDSSDSSDSSDSSDSSDS 1171 Query: 290 APERASSKTSPHWKESGASHLSFPKNSKYEYD-PDISPPRKKQAKSHFGDKKQLDSKGDC 348 + SS +S S +S S +S D D S S D D Sbjct: 1172 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1231 Query: 349 QKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSD 405 +++DS SS S SDS S + SDS SDSD Sbjct: 1232 NESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSD 1288 Score = 50.8 bits (120), Expect = 4e-06 Identities = 78/292 (26%), Positives = 102/292 (34%), Gaps = 30/292 (10%) Query: 122 DTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIR 181 D+ DSS + D S D D+ D S D+ D S + SD+S Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS--- 1067 Query: 182 HDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSP 241 DSSD+S + S S NSS +S DS D S SSD SS Sbjct: 1068 -DSSDSSDSSDSSDSSE--SSDSSDSSNSSDSSDSSDSSDSSDSSD-------SSD-SSD 1116 Query: 242 RRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPH 301 +NS D+S SSD+ DS D + + S S + SS +S Sbjct: 1117 SSDSSNSSDSS----DSSDSS-------DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDS 1165 Query: 302 WKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRH 361 S +S S NS D S S D D ++DS SS Sbjct: 1166 SDSSDSSDSSDSSNSS-----DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1220 Query: 362 KQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQ 413 S SDS+ S + S S+ S + S SD + SQ Sbjct: 1221 DSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQ 1272 Score = 50.4 bits (119), Expect = 5e-06 Identities = 71/298 (23%), Positives = 105/298 (35%), Gaps = 23/298 (7%) Query: 130 RVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDT-----SPPRRIRHDS 184 +V H D +D+ D + + D P+ S D+++ S R + Sbjct: 435 KVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYN 494 Query: 185 SDTSPPRRARHDSP----DPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISS 240 SD S DS D S +NS +D D S + + SSD S Sbjct: 495 SDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDS 554 Query: 241 PRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSP 300 +NS D+S + S + + DS D + + + S + + + S S Sbjct: 555 SDS--SNSSDSSDSS-DSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSS 611 Query: 301 HWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPR 360 +S S S +SK E D S + + S+ D D +++S SS Sbjct: 612 DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDS 671 Query: 361 HKQSPGHQDSD-------SDLSPPRNRPRHR----SSDSDLSPPRRRQRTKSSDSDLS 407 S SD SD S N SSDSD S + SSDSD S Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSS 729 Score = 50.4 bits (119), Expect = 5e-06 Identities = 75/291 (25%), Positives = 104/291 (35%), Gaps = 33/291 (11%) Query: 115 SNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDT 174 SNR ++ DSS + D S D D+ D + D+ D S + DS Sbjct: 856 SNRSDSSNSSDSS------DSSDSSNSSDSSDSSDSNESSNSSDSSDSS--NSSDSDSSD 907 Query: 175 SPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHG 234 S DSS++S + + S + NSS +S DS D S Sbjct: 908 SSNSSDSSDSSNSSDSSESSNSSDN--------SNSSDSSNSSDSSDSSDSS-------N 952 Query: 235 SSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERA 294 SSD S+ N+S + + SSD+ DS D + + S S + Sbjct: 953 SSDSSNSSDSSNSSDSSDSNSSDSSDSSN----SSDSSDSSDSSDSSDSSDSSNSSDSSD 1008 Query: 295 SSKTSPHWKESGASHLSFPKNSKYEYD-PDISPPRKKQAKSHFGDKKQLDSKGDCQKATD 353 SS +S S +S+ S NS D D S S D D ++D Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1068 Query: 354 SDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDS 404 S SS S + SDS S + S SD S + SSDS Sbjct: 1069 SSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS-----DSSDSSDS 1114 Score = 49.3 bits (116), Expect = 1e-05 Identities = 78/305 (25%), Positives = 105/305 (34%), Gaps = 17/305 (5%) Query: 110 NEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGAR 169 N SN D+ DSS + + D S D D+ + S D+ D G+ Sbjct: 799 NSSDSSNSSDSSDSSDSSDSDSSNSS-DSSNSSDSSDSSNSSDSSDSSDSSD-----GSD 852 Query: 170 HDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPR 229 DS DSSD+S + DS D S NSS +S DS Sbjct: 853 SDSSNRSDSSNSSDSSDSSDSSNSS-DSSDSSDSNESS-NSSDSSDSSNSSDSDSSDSSN 910 Query: 230 RARHGSSDISSPRRVHNNSPDTSRR--TLGSSDTQQLRRARHDSPDL----APNVTYSLP 283 + S SS +NS D S + SSD+ + + S + N + S Sbjct: 911 SSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 970 Query: 284 RTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYD-PDISPPRKKQAKSHFGDKKQL 342 S + SS +S S +S S NS D D S S+ D Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS 1030 Query: 343 DSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSS 402 D ++DS SS S SDS S + S SD S + + SS Sbjct: 1031 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD--SSESSDSS 1088 Query: 403 DSDLS 407 DS S Sbjct: 1089 DSSNS 1093 Score = 47.8 bits (112), Expect = 3e-05 Identities = 71/298 (23%), Positives = 105/298 (35%), Gaps = 21/298 (7%) Query: 115 SNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDT 174 SN ++ DSS + D S D D+ D S R ++ D S + + SD+ Sbjct: 821 SNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDS-DSSNRSDSSNSSDSSDSSDSSNSSDS 879 Query: 175 SPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHG 234 S DSSD++ + S + +SS +S +S D S + Sbjct: 880 S-------DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932 Query: 235 S-------SDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKS 287 S S SS +NS D+S + S+ + DS D + + S S Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992 Query: 288 GKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQA-KSHFGDKKQLDSKG 346 + SS +S S +S S +S D S + S D Sbjct: 993 DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052 Query: 347 DCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDS 404 D ++DS SS S SDS S + S+ SD S + SSDS Sbjct: 1053 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS-----DSSDSSDS 1105 Score = 47.0 bits (110), Expect = 5e-05 Identities = 60/248 (24%), Positives = 91/248 (36%), Gaps = 9/248 (3%) Query: 161 DPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRH 220 D S ++SD++ +D +D S + + DS D + S S Sbjct: 513 DDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSS 572 Query: 221 DSPDPSPPRRARHGSSDIS-SPRRVHNNSPDT--SRRTLGSSDTQQLRRARHDSPDLAPN 277 DS S + SSD S S +NS D+ S + SSD+ ++ DS + Sbjct: 573 DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632 Query: 278 VTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQA-KSHF 336 + S ++ S + SS S S +S+ S +S D S + S Sbjct: 633 SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692 Query: 337 GDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRR 396 D D ++DSD S + DSDS S + + S SD S Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS----- 747 Query: 397 QRTKSSDS 404 + SSDS Sbjct: 748 DSSNSSDS 755 Score = 47.0 bits (110), Expect = 5e-05 Identities = 67/287 (23%), Positives = 103/287 (35%), Gaps = 13/287 (4%) Query: 122 DTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIR 181 ++ DSS + + S D ++ D S D+ D S + + SD+S Sbjct: 910 NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS--- 966 Query: 182 HDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSP 241 DSSD++ + + S +SS +S DS D S + + S +S Sbjct: 967 -DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS 1025 Query: 242 RRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPH 301 +++ S + SSD+ DS D + + S S + SS +S Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSD----SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081 Query: 302 WKESGASHLSFPKNSKYEYDP-DISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPR 360 + S +S S +S D D S S D D ++DS SS Sbjct: 1082 SESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 1141 Query: 361 HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLS 407 S + SDS S + SSDS S S+ SD S Sbjct: 1142 SDSSDSSESSDSSDSSDSSD----SSDSSDSSDSSDSSDSSNSSDSS 1184 Score = 46.6 bits (109), Expect = 7e-05 Identities = 75/284 (26%), Positives = 101/284 (35%), Gaps = 33/284 (11%) Query: 122 DTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIR 181 D+ DSS + D S D D+ + S ++ D S + + SD+S Sbjct: 893 DSSDSS-NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS------ 945 Query: 182 HDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSP 241 DSSD+S + + S + NSS +S DS D S SSD SS Sbjct: 946 -DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD-------SSD-SSD 996 Query: 242 RRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPH 301 +NS D SSD+ DS D + + S S + SS +S Sbjct: 997 SSDSSNSSD-------SSDSS-------DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042 Query: 302 WKESGASHLSFPKNSKYEYD-PDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPR 360 S +S S NS D D S S D + D ++DS SS Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102 Query: 361 HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDS 404 S SDS S + S SD S + SSDS Sbjct: 1103 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSDSSNSSDS 1144 Score = 46.6 bits (109), Expect = 7e-05 Identities = 72/267 (26%), Positives = 97/267 (36%), Gaps = 41/267 (15%) Query: 122 DTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIR 181 D+ DSS + D S D D+ D S D+ D S + + SD+S Sbjct: 1074 DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS------ 1127 Query: 182 HDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGS-SDISS 240 DSSD+S DS D S NSS +S DS D S + S S SS Sbjct: 1128 -DSSDSS-------DSSDSS-------NSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1172 Query: 241 PRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSP 300 +NS D+S SSD+ DS D + + S S + SS +S Sbjct: 1173 DSSDSSNSSDSS----DSSDSSD----SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1224 Query: 301 HWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPR 360 S ++ S +S D S + S DS D +DS S Sbjct: 1225 SSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSS-------DSTSDSNDESDSQSKSGN 1277 Query: 361 HKQSPGHQDSDSDLSPPRNRPRHRSSD 387 + DSDS+ S H +SD Sbjct: 1278 GNNNGSDSDSDSEGSD----SNHSTSD 1300 Score = 45.8 bits (107), Expect = 1e-04 Identities = 70/311 (22%), Positives = 111/311 (35%), Gaps = 24/311 (7%) Query: 107 GGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDP----SPRRARHDTPDP 162 G + D + + D+ DS + D S D D+ D S + D+ D Sbjct: 533 GNDDNDKSDSGKGKSDSSDSD-------SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDS 585 Query: 163 SPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDS 222 + DS S DSSD+S + S S + + +SS + + DS Sbjct: 586 DSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKS---DS 642 Query: 223 PDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARH-----DSPDLAPN 277 D + + + S SS ++S D+S SSD+ + + DS D + + Sbjct: 643 SDSNSSDSSDNSDSSDSSNSSNSSDSSDSS----DSSDSSSSSDSSNSSDSSDSSDSSNS 698 Query: 278 VTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYD-PDISPPRKKQAKSHF 336 S S +S ++ + +S +S+ S +S D D S S Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758 Query: 337 GDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRR 396 D D ++DS SS + SDS S + + S SD S Sbjct: 759 SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDS 818 Query: 397 QRTKSSDSDLS 407 + SSDS S Sbjct: 819 DSSNSSDSSNS 829 Score = 43.9 bits (102), Expect = 4e-04 Identities = 69/288 (23%), Positives = 100/288 (34%), Gaps = 16/288 (5%) Query: 122 DTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGA-RHDSDTSPPRRI 180 ++ D+S + D S D ++ D S ++ D S + DS S Sbjct: 928 NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSD 987 Query: 181 RHDSSDTSPPRRARH--DSPDPSPPRRPQH--NSSGASPRRVRHDSPDPSPPRRARHGSS 236 DSSD+S + + DS D S + +SS +S DS D S + S Sbjct: 988 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047 Query: 237 DISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASS 296 S +++ S + SSD+ DS D + + S S + SS Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSSDSSD----SSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103 Query: 297 KTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDL 356 +S S +S S NS D S + S D D ++DS Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS--SDSSDSSESSDSSDSSDSSD 1161 Query: 357 SSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDS 404 SS S SDS S + S SD S + SSDS Sbjct: 1162 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS-----DSSDSSDS 1204 Score = 33.1 bits (74), Expect = 0.78 Identities = 30/135 (22%), Positives = 45/135 (33%), Gaps = 5/135 (3%) Query: 283 PRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQL 342 P KS + S T G F S DP+ S ++ Sbjct: 426 PGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNS 485 Query: 343 DSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRP-----RHRSSDSDLSPPRRRQ 397 S+GD +D + S G +D DSD + N + +D + + Sbjct: 486 SSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKG 545 Query: 398 RTKSSDSDLSPPRRS 412 ++ SSDSD S S Sbjct: 546 KSDSSDSDSSDSSNS 560 Score = 30.4 bits (67), Expect = 5.0 Identities = 28/99 (28%), Positives = 36/99 (36%), Gaps = 5/99 (5%) Query: 321 DPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNR 380 D D S K ++ S D + D ++DSD S S DSDS S + Sbjct: 536 DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSD-----SNSSSDSDSSDSDSSDS 590 Query: 381 PRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKA 419 SSDS S S SD S S+ K+ Sbjct: 591 SDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS 629 >gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sapiens] Length = 2997 Score = 57.4 bits (137), Expect = 4e-08 Identities = 114/504 (22%), Positives = 180/504 (35%), Gaps = 96/504 (19%) Query: 174 TSPPRR----IRHDSSDTSP---PRRARHDSPDPSPPRRPQHNSSGASP--RRVRHDSPD 224 T PP + + H SS P P H SP +P + P H S + P + D Sbjct: 513 TCPPLQPHPGLHHQSSPPHPHHQPWAQLHPSPQNTPQKVPVHQHSPSEPFLEKPVPDMTQ 572 Query: 225 PSPPRRARHGSSDI---------SSPRRVHNN---SPDTSRRT-----LGSSDTQQLRRA 267 S P S D ++ NN + D S+ G D Q+L R Sbjct: 573 VSGPNAQLVKSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKGFGKDDFPGGVDNQELNRN 632 Query: 268 RHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPP 327 D K K P+ K P KE PK K P P Sbjct: 633 SLDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEP--KE--------PKTPKAPKIP--KEP 680 Query: 328 RKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHK----QSPGHQDSDSDLSPPRNRPRH 383 ++K+AK+ K SK K DS+ S+ + K ++ G ++SD D +PP + P Sbjct: 681 KEKKAKT--ATPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSPPPE 738 Query: 384 RSSDSDLSPPR--RRQRTKSSDSDLS-PPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQ 440 D + R R+ + K DL + AA S + T Q EQQ Sbjct: 739 EDEDPGVQKRRSSRQVKRKRYTEDLEFKISDEEADDADAAGRDSPSNTS------QSEQQ 792 Query: 441 ELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWG-- 498 E + +AE E + +S +K+ E +E K L+ QW Sbjct: 793 E---------SVDAEGPVVEKIMSSRSVKKQKESGEEVEIEEFYVKYKNFSYLHCQWASI 843 Query: 499 KGLAQSRQQQQNVED-AMKEMQKPLARYIDDE-------DLDRML---REQEREGDPMAN 547 + L + ++ QQ ++ K+ Q I+DE ++DR++ R + G+P+ + Sbjct: 844 EDLEKDKRIQQKIKRFKAKQGQNKFLSEIEDELFNPDYVEVDRIMDFARSTDDRGEPVTH 903 Query: 548 FIKK-----------------NKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRS 590 ++ K ++AK + +K+ R P R P W + S Sbjct: 904 YLVKWCSLPYEDSTWERRQDIDQAKIEEFEKLMSR----EPETERVERPPADDWKKSESS 959 Query: 591 NGFEQKRFARLASKKAVEELAYKW 614 ++ R + V L + W Sbjct: 960 REYKNNNKLREYQLEGVNWLLFNW 983 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 56.2 bits (134), Expect = 9e-08 Identities = 98/528 (18%), Positives = 185/528 (35%), Gaps = 56/528 (10%) Query: 60 AISTTKLEKEEEEDDGDLPVVAEFVDER----PEEVKQMEAFRSSAKWKLLGGHNEDLPS 115 A S K K +++ P A+ ++ P EVK E +S AK + P Sbjct: 509 AASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPE 568 Query: 116 NRHFRHDTPDSSPRRVRHGTPD----PSPRKDRHDTPDPSPRRARHDTPDPSPLR-GARH 170 + SP + + + P+ K P A+ SP++ A+ Sbjct: 569 KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKS 628 Query: 171 DSDTSPPRRIRHDS-SDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPD--PSP 227 ++ P + + + + P +A+ SP+ + P+ SP + SP+ SP Sbjct: 629 PAEVKSPEKAKSPTKEEAKSPEKAK--SPEKEEAKSPE---KAKSPVKAEAKSPEKAKSP 683 Query: 228 PRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKS 287 + SP + SP+ ++ + + SP+ A + P + Sbjct: 684 VKAEAKSPEKAKSPVKEEAKSPEKAKSPV---------KEEAKSPEKAKS-----PVKEE 729 Query: 288 GKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGD 347 K PE+A S K + + P+ P K++A+S DK +K Sbjct: 730 AKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSP-ADKFPEKAKSP 788 Query: 348 CQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLS 407 ++ ++ SP +SP +D+ +P + P+ S + + Q K + Sbjct: 789 VKE----EVKSPEKAKSPLKEDAK---APEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKK 841 Query: 408 PPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKS 467 P K K + + + E K++ E++ + + DK Sbjct: 842 AEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKK 901 Query: 468 -----GRKRNLKLERLEQRRKAEK---------DSERDELYAQWGKGLAQSRQQQQNVED 513 ++ K+E E + EK D++ E K A ++ E Sbjct: 902 KVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEK 961 Query: 514 AMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKK 561 A K +KP ED + +E + P A +K+ + + K+ K Sbjct: 962 AKKPEEKPKTEAKAKEDDKTLSKEPSK---PKAEKAEKSSSTDQKDSK 1006 >gi|50962882 G patch domain containing 8 [Homo sapiens] Length = 1502 Score = 56.2 bits (134), Expect = 9e-08 Identities = 89/421 (21%), Positives = 148/421 (35%), Gaps = 64/421 (15%) Query: 108 GHNEDLPSNRHFRH--DTPDSSP-RRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSP 164 G N+ P H DT S P ++ R G +K +H R+ + DT + S Sbjct: 641 GLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSS 700 Query: 165 LRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDP------SPPRRPQHNSSGASPRRV 218 + + +R R + ++P R P+P +PPRR + + R + Sbjct: 701 -KAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSL 759 Query: 219 RHDSPDPSPPRRARHGSSDISSPRRVHNNS--PDTSRRTLG------SSDTQQLRRARHD 270 + GSS R H P + +R G SS Q D Sbjct: 760 PAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDED 819 Query: 271 SPDLAPNVTYSLPRTK---------SGKAPERASSKTSPHWKESGASHLSFPKNSKYEYD 321 S D + + + ++ SG R+ S++ +S S+ +S D Sbjct: 820 SDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSD 879 Query: 322 PDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLS--------SPRHKQSPGHQDSDSD 373 ++ + + D S+ +++ DSD S S RHK S D D Sbjct: 880 QSCYSRQRSYSDDSYSDYSDR-SRRHSKRSHDSDDSDYASSKHRSKRHKYS--SSDDDYS 936 Query: 374 LSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLT 433 LS ++R R RS + R R R +S S S R + AH + Sbjct: 937 LSCSQSRSRSRSHTRE----RSRSRGRSRSSSCSRSRSKRRSRSTTAHSW---------- 982 Query: 434 DIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDEL 493 QR + +++ + T + + RKR+ E E+R +D R ++ Sbjct: 983 --QRSRSYSRDRSRST----------RSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKI 1030 Query: 494 Y 494 Y Sbjct: 1031 Y 1031 Score = 47.0 bits (110), Expect = 5e-05 Identities = 95/404 (23%), Positives = 144/404 (35%), Gaps = 50/404 (12%) Query: 125 DSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLR-------------GARHD 171 + P+ G+ P+P + R D S RR+ S + G +H Sbjct: 728 ERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHK 787 Query: 172 SDTSPPRRIRHD-------SSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPD 224 + P R SS S P DS D S R Q + S S DS Sbjct: 788 GELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGS 847 Query: 225 PSPPRRARHGSSDIS--SPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSL 282 R+R G S S RR +++S D S SD R R S D +YS Sbjct: 848 EHSRSRSRSGRRHSSHRSSRRSYSSSSDAS------SDQSCYSRQRSYSDD-----SYSD 896 Query: 283 PRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEY-DPDIS---PPRKKQAKSHFGD 338 +S + +R+ + S H S K KY D D S + +++SH + Sbjct: 897 YSDRSRRHSKRSHDSDDSDYASS--KHRS--KRHKYSSSDDDYSLSCSQSRSRSRSHTRE 952 Query: 339 KKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQR 398 + + S+G + ++ S S R +S S R+R R S S S R+R Sbjct: 953 RSR--SRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSW 1010 Query: 399 TKSSDSDLSPPRRSQPPGK----KAAHMY-SGAKTGLVLTDIQR--EQQELKEQDQETMA 451 S + RR K ++ H + SG G D R + + Q + Sbjct: 1011 GHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNI 1070 Query: 452 FEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYA 495 + DK+ L LE+++ R+ K S +E+ A Sbjct: 1071 GTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQA 1114 Score = 40.4 bits (93), Expect = 0.005 Identities = 68/353 (19%), Positives = 119/353 (33%), Gaps = 48/353 (13%) Query: 254 RTLGSSDTQQLRRARHDSPDLAPNVT-YSLPRTKSGK--APERASSKTSPHWKESGASH- 309 + +GSS L+ P+ + V + R+ G+ AP S+ + + +E G SH Sbjct: 593 KDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHG 652 Query: 310 -------LSFPKNSKYEYDPDISPPRKKQAKSHFGDKK-QLDSKGDCQKATDSDLSSPRH 361 S P + +KK KS +K + D++ KA + S R Sbjct: 653 SETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRK 712 Query: 362 KQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKK--- 418 K+ S + R +PPRRR+R + S P GKK Sbjct: 713 KRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEG 772 Query: 419 ----AAHMYSGAK---------------TGLVLTDIQREQQELKEQDQETMAF-----EA 454 ++ + G K T R Q ++D + + ++ Sbjct: 773 GGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKS 832 Query: 455 EFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDA 514 QY+E + SG + + R +R + + S R + +Q++ D Sbjct: 833 PSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSD- 891 Query: 515 MKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKKVRPRYS 567 Y D D R ++ + D K+++K +K YS Sbjct: 892 --------DSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYS 936 >gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] Length = 953 Score = 56.2 bits (134), Expect = 9e-08 Identities = 116/485 (23%), Positives = 167/485 (34%), Gaps = 93/485 (19%) Query: 25 DRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTAISTTKLEKEEEEDD----GDLPVV 80 DR E R++ K +PKP R + A + ++++ +E D P Sbjct: 469 DRDREKEREKEKGKPKPRSPQPPS-RQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKK 527 Query: 81 AEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDP-S 139 V P ++ +S+ N S+R + SS R R + S Sbjct: 528 KLGVSVSPSRARRRRKTSASSA----SASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYS 583 Query: 140 PRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRR--IRHDSSDTSPPRRARHDS 197 R RH + S R+R + PSP S T P R IR PP +A S Sbjct: 584 SRSSRHSSFSGSRSRSRSFSSSPSP-------SPTPSPHRPSIRTKGEPAPPPGKAGEKS 636 Query: 198 -----PDPSPPRR-------PQHNSSGASPRRVRHDSPDPSPPRR-----ARHGSSDISS 240 P P+PP+ P+ G R + P +PPRR + GS S Sbjct: 637 VKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYS 696 Query: 241 PRRVHNNSPDTSRRTLGSSDTQQLRRARH-DSPDLAPNVTYSLPRTKS-GKAPERASSKT 298 + S S + SS T A DS D+ ++ + S AP + + Sbjct: 697 GSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEK 756 Query: 299 SPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKK-------QLDSKGDCQKA 351 KE G K K + D PP K AK G K Q G Q+ Sbjct: 757 GKSKKEDGV------KEEKRKRDSSTQPP--KSAKPPAGGKSSQQPSTPQQAPPGQPQQG 808 Query: 352 T--------------DSDLSSPRHKQSPGHQDSDSDLSPPRNRP--------RHRSSDSD 389 T +D S R + P +D S PP RP R R S Sbjct: 809 TFVAHKEIKLTLLNKAADKGS-RKRYEPSDKDRQSP--PPAKRPNTSPDRGSRDRKSGGR 865 Query: 390 LSPPR-RRQRTKSSDSDLSPPRRSQP--------------PGKKAAHMYSGAKTGLVLTD 434 L P+ RQR ++S + +P R + PGK + + K+G T Sbjct: 866 LGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKASTL 925 Query: 435 IQREQ 439 +RE+ Sbjct: 926 SRREE 930 Score = 35.8 bits (81), Expect = 0.12 Identities = 26/104 (25%), Positives = 50/104 (48%), Gaps = 14/104 (13%) Query: 469 RKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDD 528 R+R + ER ++R+ E++ ERD + + + R+ +++ E ++ + R D Sbjct: 402 RERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRD 461 Query: 529 EDLDRMLREQEREGDPMANFIKKNKAKENKNKKVRPRYSGPAPP 572 E DR R+++RE KE + +K +P+ P PP Sbjct: 462 EK-DRQHRDRDRE-------------KEREKEKGKPKPRSPQPP 491 Score = 32.7 bits (73), Expect = 1.0 Identities = 52/251 (20%), Positives = 98/251 (39%), Gaps = 41/251 (16%) Query: 319 EYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPR 378 E DP SP ++Q + D DS +D DL + S + + P + Sbjct: 8 ERDPH-SPEDEEQPQGLSDDDILRDS------GSDQDLDGAGVRASDLEDEESAARGPSQ 60 Query: 379 NRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQRE 438 + S + D R KS D D S+ P +D++ E Sbjct: 61 EEEDNHSDEED-----RASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDE 115 Query: 439 QQEL-KEQDQETMAFEAEF--QYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDE-LY 494 + +E D+ + ++ E + A V D++ ++ AE D E+ E Sbjct: 116 ASSVTRELDEHELDYDEEVPEEPAPAVQEDEA------------EKAGAEDDEEKGEGTP 163 Query: 495 AQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKA 554 + GK QS +++++E A ++ ++ IDD ++D + +++ + Sbjct: 164 REEGKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEID-------------DDDLEEGEV 210 Query: 555 KENKNKKVRPR 565 K+ ++KVRPR Sbjct: 211 KDPSDRKVRPR 221 Score = 30.0 bits (66), Expect = 6.6 Identities = 23/115 (20%), Positives = 44/115 (38%), Gaps = 17/115 (14%) Query: 329 KKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDS 388 +++AK D++ D + ++ + PR Q P Q P+ + +D Sbjct: 455 RERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADE 514 Query: 389 -----------------DLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGA 426 +SP R R+R K+S S S S+ + +++ SG+ Sbjct: 515 WKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGS 569 >gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] Length = 3957 Score = 55.5 bits (132), Expect = 1e-07 Identities = 54/193 (27%), Positives = 75/193 (38%), Gaps = 11/193 (5%) Query: 111 EDLPSNR-HFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGAR 169 ED+P H H S + RH PSP+ +RH T S + RH P SP Sbjct: 1795 EDVPKKTTHRPHPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERH--PPVSPSSKTE 1852 Query: 170 HDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPR 229 S SP + S +S + +H SP SP + + +S +S + RH PS Sbjct: 1853 KHSPVSPSAKTERHSPASSSSKTEKH-SP-VSPSTKTERHSPVSSTKTERHPPVSPSGKT 1910 Query: 230 RARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGK 289 R S + SP + + L S + R +H A LP + SGK Sbjct: 1911 DKRPPVSPSGRTEKHPPVSPGRTEKRLPVSPSG--RTDKHQPVSTAGKTEKHLPVSPSGK 1968 Query: 290 A----PERASSKT 298 P +SKT Sbjct: 1969 TEKQPPVSPTSKT 1981 Score = 34.7 bits (78), Expect = 0.27 Identities = 77/331 (23%), Positives = 119/331 (35%), Gaps = 62/331 (18%) Query: 196 DSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRT 255 DS + SP + NSS +P DS +PSP + + S SSP P Sbjct: 2435 DSLEASPVL--EDNSSHKTP-----DSLEPSPLKESPCRDSLESSPVE-----PKMKAGI 2482 Query: 256 LGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLS--FP 313 S A+ + +V L R G A + + +TS + SG S LS P Sbjct: 2483 FPSHFPLPAAVAKTELLTEVASVRSRLLRDPDGSAEDDSLEQTSL-MESSGKSPLSPDTP 2541 Query: 314 KNSKYEYD-----PDISPPRK-------KQAKSHFGDKKQLDSKGDCQKATDSDL----- 356 + + Y+ D+S P+ ++ S G+KK+ + + K Sbjct: 2542 SSEEVSYEVTPKTTDVSTPKPAVIHECAEEDDSENGEKKRFTPEEEMFKMVTKIKMFDEL 2601 Query: 357 -----------SSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSP----PRRRQRTKS 401 P+ ++S D D+D S + P+H S D S R S Sbjct: 2602 EQEAKQKRDYKKEPKQEESSSSSDPDADCSVDVDEPKHTGSGEDESGVPVLVTSESRKVS 2661 Query: 402 SDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQEL---KEQDQETMAFEAEFQY 458 S S+ P + A + GA +GL+ + R Q D + E +FQ Sbjct: 2662 SSSESEP---------ELAQLKKGADSGLLPEPVIRVQPPSPLPSSMDSNSSPEEVQFQ- 2711 Query: 459 AETVFRDKSGRKRNLKLERLEQRRKAEKDSE 489 V + K N + + + EKDSE Sbjct: 2712 --PVVSKQYTFKMNEDTQEEPGKSEEEKDSE 2740 >gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] Length = 330 Score = 54.7 bits (130), Expect = 2e-07 Identities = 68/257 (26%), Positives = 105/257 (40%), Gaps = 53/257 (20%) Query: 11 EYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA------ISTT 64 EY++R S + E GRK++K R K G + D + +S Sbjct: 113 EYIEREESDGEY-----DEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKY 167 Query: 65 KLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTP 124 KL+++E+EDD DL E + K+ RS +K + + H R + Sbjct: 168 KLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSR-----------SSHSRSSSR 216 Query: 125 DSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDT------SPPR 178 SSP R S + R + S R+R + + S RG++ S + S PR Sbjct: 217 SSSPSSSR------SRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR 270 Query: 179 RIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSG-ASPRRVRHDSPDPSPPRRARHGSSD 237 + + SS +SP R + R + +SSG RR R SP+ RH SS Sbjct: 271 KRSYSSSSSSPERNRKRS--------RSRSSSSGDRKKRRTRSRSPE------RRHRSSS 316 Query: 238 ISSPRRVHNNSPDTSRR 254 SS H+ S +S++ Sbjct: 317 GSS----HSGSRSSSKK 329 Score = 39.7 bits (91), Expect = 0.008 Identities = 43/161 (26%), Positives = 69/161 (42%), Gaps = 13/161 (8%) Query: 270 DSPDLAP-NVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPR 328 D DL+ N+ S + K R S S +S S P +S+ Sbjct: 176 DDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS 235 Query: 329 KKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQD-SDSDLSPPRNRPRHRSSD 387 Q++S +++ S+G +++ S R SP + S S SP RNR R RS Sbjct: 236 SSQSRSRSSSRERSRSRGSKSRSSSR---SHRGSSSPRKRSYSSSSSSPERNRKRSRSRS 292 Query: 388 SDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKT 428 S S R+++RT+S SP RR + + +SG+++ Sbjct: 293 SS-SGDRKKRRTRSR----SPERRHR---SSSGSSHSGSRS 325 Score = 35.0 bits (79), Expect = 0.20 Identities = 41/165 (24%), Positives = 61/165 (36%), Gaps = 17/165 (10%) Query: 158 DTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPP-----RRPQHNSSG 212 D D S + + S ++ S S +R S SP R + SS Sbjct: 176 DDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS 235 Query: 213 ASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSP 272 +S R R S + R+R S S R H S +R+ SS + R + Sbjct: 236 SSQSRSRSSSRE-----RSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRS 290 Query: 273 DLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSK 317 + + RT+S ++PER H SG+SH +SK Sbjct: 291 RSSSSGDRKKRRTRS-RSPERR------HRSSSGSSHSGSRSSSK 328 Score = 33.1 bits (74), Expect = 0.78 Identities = 39/199 (19%), Positives = 70/199 (35%), Gaps = 9/199 (4%) Query: 314 KNSKYEYDPDISPPRKKQAKSHFGDK---KQLDSKGDCQKATDSDLSSPRHKQSPGHQDS 370 + S EYD + +KK G K+++ K + D D ++K + Sbjct: 118 EESDGEYD-EFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDED 176 Query: 371 DSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGL 430 D+DLS N DS+ RR R+KS S RS P + S +++ Sbjct: 177 DADLSK-YNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS 235 Query: 431 VLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSER 490 R + + + + + + + + S RKR+ R ++ R Sbjct: 236 SSQSRSRSSSRERSRSRGSKSRSSSRSHRGS----SSPRKRSYSSSSSSPERNRKRSRSR 291 Query: 491 DELYAQWGKGLAQSRQQQQ 509 K +SR ++ Sbjct: 292 SSSSGDRKKRRTRSRSPER 310 >gi|78042577 MAP7 domain containing 1 [Homo sapiens] Length = 841 Score = 53.9 bits (128), Expect = 4e-07 Identities = 77/425 (18%), Positives = 151/425 (35%), Gaps = 39/425 (9%) Query: 24 VDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTAISTTKLEKEEEEDDGDLPVVAEF 83 V R + +G + +++P GG+ R + A K EK+++E + + A Sbjct: 379 VHRCAPAGERGERRKPNAGGSPAPVRRRPE------ASPVQKKEKKDKERENEKEKSAL- 431 Query: 84 VDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPR-- 141 R +K+ ++ +S + +L +L R +P +S R P P P Sbjct: 432 --ARERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHT 489 Query: 142 ------KDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSP--PRRA 193 R T P R R + SP D S RR ++ +P P + Sbjct: 490 LPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSK-RRASNEKESAAPASPAPS 548 Query: 194 RHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSP---PRRARHGSSDISSPRRVHNNSPD 250 SP P+PP++ Q + + V P P+P P + G++D R+ Sbjct: 549 PAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRR 608 Query: 251 TSRRTLGSSDTQQLRRARHD----SPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESG 306 +R + ++ +A D LA R + E ++ ++ Sbjct: 609 QAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEE 668 Query: 307 ASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGD------CQKATDSDLSSPR 360 L K + + ++ + + HF ++Q + ++ S++S + Sbjct: 669 QERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETK 728 Query: 361 HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAA 420 KQ +++ P R SP +++ + + P+ S P + A Sbjct: 729 QKQDSKEANANGSSPEPVKAVEAR------SPGLQKEAVQKEEPIPQEPQWSLPSKELPA 782 Query: 421 HMYSG 425 + +G Sbjct: 783 SLVNG 787 Score = 45.1 bits (105), Expect = 2e-04 Identities = 88/439 (20%), Positives = 155/439 (35%), Gaps = 72/439 (16%) Query: 190 PRRARHDSPDPSPPRRPQHNSSGAS------PRRVRHDSPDPSPPRRARHGS-SDISSPR 242 PR R P R P +GAS P R + P PR A + S R Sbjct: 318 PRNGRDQGRGCDPGRGPTWGRAGASLARGPQPDRTHPSAAVPVCPRSASASPLTPCSVTR 377 Query: 243 RVHN----------------NSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTK 286 VH SP RR +S Q ++ + D +L R + Sbjct: 378 SVHRCAPAGERGERRKPNAGGSPAPVRRRPEASPVQ--KKEKKDKERENEKEKSALARER 435 Query: 287 SGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDIS-----------------PPRK 329 S K + + S AS LS PK+ P S PP+ Sbjct: 436 SLKKRQSLPASPRARLSASTASELS-PKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKP 494 Query: 330 KQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSD 389 + K + + K + S QS ++ + + P + + Sbjct: 495 PSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPT 554 Query: 390 LSPPRRRQRTKSSDSDL----SPPRRSQP--PGKKAAHMYSGAKTGLVLTDIQREQQELK 443 +PP++ Q + +D SPP + P P K A + +L + +R+ +E + Sbjct: 555 PAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQR 614 Query: 444 EQDQETMAFEAEFQYA---ETVFRDKSGR-KRNLKLERLEQRRKAEK----DSERDELYA 495 E++++ +AE E + R+ R +R + R E++ EK E++ L Sbjct: 615 EREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQK 674 Query: 496 QWGKGLAQSR---------------QQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQER 540 Q + A+SR QQ+Q ++ K +++ + R E + ++ + Sbjct: 675 QKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSK 734 Query: 541 EGDPMANFIKKNKAKENKN 559 E + + + KA E ++ Sbjct: 735 EANANGSSPEPVKAVEARS 753 Score = 43.9 bits (102), Expect = 4e-04 Identities = 50/228 (21%), Positives = 84/228 (36%), Gaps = 30/228 (13%) Query: 283 PRTKSGK-APERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQ 341 PR + G AP ++T P + S S P PD +PP A + KQ Sbjct: 5 PRAELGAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPD-TPPDTPPAMKNATSSKQ 63 Query: 342 LDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKS 401 L + + +P ++SP + +PP PR Sbjct: 64 LPLEPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPR------------------- 104 Query: 402 SDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAET 461 D PPRRS P A T + + KE+ +E + A + Sbjct: 105 ---DARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKYLAA---KKA 158 Query: 462 VFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQ 509 V+ +K + + L+ ++L++RR+ E L A+ + + RQ+Q+ Sbjct: 159 VWLEKEEKAKALREKQLQERRRR---LEEQRLKAEQRRAALEERQRQK 203 Score = 39.7 bits (91), Expect = 0.008 Identities = 29/125 (23%), Positives = 48/125 (38%), Gaps = 2/125 (1%) Query: 148 PDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQ 207 P+P P +P P P+ D+ P +++ +S P S P P Sbjct: 23 PEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPAPP 82 Query: 208 HNSSGASPRRVRHDSPDPSPPRRAR--HGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLR 265 S +S + R +P PR AR SS S ++SP T + + + +L Sbjct: 83 QEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLA 142 Query: 266 RARHD 270 + R + Sbjct: 143 KERRE 147 >gi|4503509 eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa [Homo sapiens] Length = 1382 Score = 53.5 bits (127), Expect = 6e-07 Identities = 113/503 (22%), Positives = 173/503 (34%), Gaps = 77/503 (15%) Query: 88 PEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTP-DPSPRKDRHD 146 PE + +W+ G +ED R R D + PRR+ +PS R D Sbjct: 903 PEADSEWRRGPPEKEWRRGEGRDED----RSHRRD--EERPRRLGDDEDREPSLRPDDDR 956 Query: 147 TP------DPSPRRARHDTPDPSPLRGA-------RHDSDTSPPRRIRHD-------SSD 186 P D PRR + D RGA R+ D PPRRI + + D Sbjct: 957 VPRRGMDDDRGPRRGPEE--DRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADD 1014 Query: 187 TSPPRRARHD-------SPDPSPPRRPQHNSSGASPRRVRHDSPDPS-----PPRRARHG 234 PPRR + + + PRR + G PRR D S R R G Sbjct: 1015 DRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRG--PRRGGADDERSSWRNADDDRGPRRG 1072 Query: 235 SSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPR-----TKSGK 289 D PRR ++ R G D + RR D D P R + Sbjct: 1073 LDDDRGPRRGMDDDRGPRR---GMDDDRGPRRGMDD--DRGPRRGLDDDRGPWRNADDDR 1127 Query: 290 APERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKG--- 346 P R + W+ LS D D P R ++ G + L G Sbjct: 1128 IPRRGAEDDRGPWRNMDDDRLS------RRADDDRFPRRGDDSRP--GPWRPLVKPGGWR 1179 Query: 347 DCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDL 406 + +KA + PR +S ++ + D R+R ++D P R R R + D + Sbjct: 1180 EKEKAREESWGPPR--ESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDRE- 1236 Query: 407 SPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDK 466 R + P + A+ D R ++ + + + + D+ Sbjct: 1237 ---DRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDR 1293 Query: 467 SGRKRNLKLERLE-------QRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQ 519 R L+ ER E RK ++ ERD L++ R++ ++ E ++ + Sbjct: 1294 DRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEK 1353 Query: 520 KPLARYIDDEDLDRMLREQEREG 542 D E L R E + +G Sbjct: 1354 ASWRAEKDRESLRRTKNETDEDG 1376 Score = 38.1 bits (87), Expect = 0.024 Identities = 39/174 (22%), Positives = 77/174 (44%), Gaps = 37/174 (21%) Query: 427 KTGLVLTDIQREQQELKEQ----------DQETMAFEAEFQYAETVFRDKSGRKRNLKLE 476 K L +IQRE++EL+++ ++E + EA+ + E + ++ K+ E Sbjct: 579 KERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRE 638 Query: 477 RLEQRRKAE------KDSERDELYAQ-----WGKGLAQSRQQQQNVEDAMKEMQKPL--- 522 RLEQ +K E KD + ++L K + Q ++++ +++ +K +K + Sbjct: 639 RLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYF 698 Query: 523 -------------ARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKKVR 563 + Y + D L EQ+ E +++ KA E+KN+ R Sbjct: 699 ERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSR 752 Score = 33.9 bits (76), Expect = 0.46 Identities = 20/66 (30%), Positives = 37/66 (56%), Gaps = 5/66 (7%) Query: 436 QREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEK---DSERDE 492 +RE+ E ++++E ++ + E V R K R+R L++E E+RR+ E+ DS Sbjct: 828 ERERAERAKREEELREYQERVKKLEEVERKK--RQRELEIEERERRREEERRLGDSSLSR 885 Query: 493 LYAQWG 498 ++WG Sbjct: 886 KDSRWG 891 Score = 31.6 bits (70), Expect = 2.3 Identities = 25/104 (24%), Positives = 44/104 (42%), Gaps = 15/104 (14%) Query: 440 QELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGK 499 +E K Q +E E Y ++ R L+ E+R +AE+ +EL Sbjct: 792 EERKRQRKE----ERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEEL------ 841 Query: 500 GLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGD 543 R+ Q+ V+ + +K R ++ E+ +R E+ R GD Sbjct: 842 -----REYQERVKKLEEVERKKRQRELEIEERERRREEERRLGD 880 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 53.1 bits (126), Expect = 7e-07 Identities = 84/425 (19%), Positives = 157/425 (36%), Gaps = 46/425 (10%) Query: 153 RRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSG 212 R ++P L A D+D R R + +R D RR + + Sbjct: 30 RPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHR 89 Query: 213 ASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGS--------SDTQQL 264 R R D R + + N + R T +D Q+ Sbjct: 90 KRDRH-RERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRE 148 Query: 265 RRARHDSPDLAPNVT--YSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDP 322 R + D+ T +T+ + ER K +E K + Sbjct: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSER 208 Query: 323 DISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPR 382 R+++ ++ K+Q D + D Q+ T+ + R KQ+ + S+ + + R R Sbjct: 209 GRERERERETETETERKRQTDRERDRQRKTERE----REKQAERERASERETERDKERER 264 Query: 383 HRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQEL 442 R D D RRQ+ + +D RR++ + T+ +RE+Q Sbjct: 265 ERDRDRDRD---RRQKERERQTDRKRQRRTERDRE---------------TERKRERQRE 306 Query: 443 KEQDQE-TMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGL 501 +E+++E E E + R + + K +++R+ E D ER+ Q G+ Sbjct: 307 RERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNR---QTGR-- 361 Query: 502 AQSRQQQQNVEDAMKEMQKPLARYIDDEDLDR-MLREQEREGDPMANFIKKNKAKENKNK 560 + R+Q + + +E + AR ++ + DR R++ERE +K++ + + + Sbjct: 362 -EGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ-----TEKDRDGQRETE 415 Query: 561 KVRPR 565 K R R Sbjct: 416 KQRER 420 Score = 47.0 bits (110), Expect = 5e-05 Identities = 80/466 (17%), Positives = 169/466 (36%), Gaps = 52/466 (11%) Query: 98 RSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRK-DRHDTPDPSPRRAR 156 + S + + LG ++D + R+ + RR + T + RK +R D +R R Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93 Query: 157 HDTPDPSPLRGARHDSDTSPPR-----RIRHDSSDTSPPR---RARHDSPDPSPPRRPQH 208 H + +D R R R + R R R D R Q Sbjct: 94 HRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153 Query: 209 NSSGASPRRVRHDSPDPSPPRRARHGSSDIS-SPRRVHNNSPDTSRRTLGSSDTQQLRRA 267 ++ R+ + + R + + + RR + +T + R Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERE 213 Query: 268 RHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPP 327 R + R + + + + + K + E D D Sbjct: 214 RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD 273 Query: 328 RKKQAKSHFGDKK-QLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSS 386 R+++ + D+K Q ++ D + + R ++ ++ + + R R R R + Sbjct: 274 RRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRET 333 Query: 387 DSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQD 446 + D R R+R + ++ D R++ G++ A +RE++ +E+D Sbjct: 334 ERDREKERERKRKRQTEMDRERNRQTGREGRRQA---------------ERERERERERD 378 Query: 447 QETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQR-RKAEKDSERDELYAQWGKGLAQSR 505 +++ R++ R+R+ +R ++R R+ EKD + G ++ Sbjct: 379 RQSA-------------REREERERDRDRDRQKERERQTEKDRD----------GQRETE 415 Query: 506 QQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKK 551 +Q++ +D +E ++ R + E R++ER+ D A +K Sbjct: 416 KQREREKD--RESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459 Score = 31.2 bits (69), Expect = 3.0 Identities = 86/411 (20%), Positives = 131/411 (31%), Gaps = 30/411 (7%) Query: 25 DRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTAISTTKLEKEEE-EDDGDLPVVAEF 83 DR E R R+K+R + G+ R D EKE E + D + E Sbjct: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173 Query: 84 VDERPEE-VKQMEAFRSSAKWKLLGGHNEDLPSNR-----HFRHDTPDSSPRRVRHGTPD 137 ++ E K + R + + ED S R R ++ +R D Sbjct: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD 233 Query: 138 PSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDS 197 + +R RA + R D D RR + T R+ R + Sbjct: 234 RQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTER 293 Query: 198 PDPSPPRRPQHNSSGASPRRVRHDSPDPSPPR---RARHGSSDISSPR---RVHNNSPDT 251 + +R + R R + R R R D R R D Sbjct: 294 DRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDR 353 Query: 252 SR-RTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHL 310 R R G +Q R R + R + + ER + KE Sbjct: 354 ERNRQTGREGRRQAERERERERER--------DRQSAREREERERDRDRDRQKER---ER 402 Query: 311 SFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDS 370 K+ + + + R+K +S G ++ + + QK + D +Q+ G Q Sbjct: 403 QTEKDRDGQRETEKQREREKDRESERG--RERGREREKQKGRERDRERQTDRQA-GRQRK 459 Query: 371 DSDL--SPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKA 419 S L +PP R SD + P R R KSS D P G+ A Sbjct: 460 RSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPA 510 >gi|50083281 KIAA1853 protein [Homo sapiens] Length = 611 Score = 53.1 bits (126), Expect = 7e-07 Identities = 80/386 (20%), Positives = 126/386 (32%), Gaps = 38/386 (9%) Query: 135 TPDPSPRKDRHDTPDPSPRRARHDTPDPSPLR------GARHDSDTSPPRRIRHDSSDTS 188 TP PS R + +R R + PSP++ +H S ++ RH SS Sbjct: 101 TPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPK 160 Query: 189 PPRR--ARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHN 246 RR RH S PR+ + P R + PS G S + Sbjct: 161 SKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRR 220 Query: 247 NSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESG 306 +S S+ S Q R + ++ T SG A + + SP G Sbjct: 221 HSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRG 280 Query: 307 ASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPG 366 ++ +Y+ D S P Q S S+G + + LS R S Sbjct: 281 -------RSQEYDSGNDTSSPPSTQTSS-------ARSRGQEKGSPSGGLSKSRELNSGN 326 Query: 367 HQDSDSDL--SPPRNR----------PRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQP 414 DS + S P+N+ R R S SP K S S R S Sbjct: 327 TSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPM 386 Query: 415 PGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRK---- 470 G + Y+ ++ + + + + + E + KSG++ Sbjct: 387 KGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPS 446 Query: 471 RNLKLERLEQRRKAEKDSERDELYAQ 496 R+ + R + ERD Y++ Sbjct: 447 RSSRSRRSPSYSRYSPSRERDPKYSE 472 Score = 42.4 bits (98), Expect = 0.001 Identities = 74/290 (25%), Positives = 105/290 (36%), Gaps = 24/290 (8%) Query: 147 TPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRP 206 T P + A + P+ RG SP + P AR SP + Sbjct: 336 TSSPQNKGAMLENLSPTS-RGRESRGFQSPCLECAEVKKSSLVPSTARS-----SPMKGC 389 Query: 207 QHNSSGASPRRVRHDSPDPSPPRRARHGSS-DISSPRRVHNNSPDTSRRTLGSSDTQQLR 265 +SS AS R H S P+P R+ S SS +R ++ SP S ++ S + Sbjct: 390 SRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSS 449 Query: 266 RARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPD-- 323 R+R SP + YS R + K E+ S + S P + P Sbjct: 450 RSRR-SPSYS---RYSPSRERDPKYSEKDSQQRERERARRRRRSYS-PMRKRRRDSPSHL 504 Query: 324 ----ISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDS-DLSPPR 378 I+ RK+ + + S G + SS S + S S S R Sbjct: 505 EARRITSARKRPIPYY---RPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRR 561 Query: 379 NRPRHRSSDSDLSP-PRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAK 427 +R R SS S SP P R R++S S RSQ +A YS + Sbjct: 562 SRTRTSSSSSSRSPSPGSRSRSRSRSRSRS-RSRSQSRSYSSADSYSSTR 610 Score = 40.0 bits (92), Expect = 0.006 Identities = 54/253 (21%), Positives = 89/253 (35%), Gaps = 21/253 (8%) Query: 159 TPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRV 218 T SP++G S + R H S +P R+ + + ++ S + + Sbjct: 380 TARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKS 439 Query: 219 RHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNV 278 SP R R S SP R P S + + ++ RR R + Sbjct: 440 GKRSPPSRSSRSRRSPSYSRYSPSR--ERDPKYSEKDSQQRERERARRRRRSYSPMRKRR 497 Query: 279 TYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGD 338 S P + A + P+++ S +S S S + S + ++S+ Sbjct: 498 RDS-PSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWY----SSSSSRSASRSYSRS 552 Query: 339 KKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQR 398 + + S+ + T S SS +SP P +R R RS S R + R Sbjct: 553 RSRSRSRRRSRTRTSSSSSS----RSPS----------PGSRSRSRSRSRSRSRSRSQSR 598 Query: 399 TKSSDSDLSPPRR 411 + SS S RR Sbjct: 599 SYSSADSYSSTRR 611 Score = 35.4 bits (80), Expect = 0.16 Identities = 45/184 (24%), Positives = 64/184 (34%), Gaps = 27/184 (14%) Query: 123 TPDSSPRRVRHGTPDPSPRKDR---HDTPDPS----PRRARHDTPDPSPLRGARHDSDTS 175 +P S + + P S R R + PS P+ + D+ R R S Sbjct: 432 SPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYS 491 Query: 176 PPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSG---------------ASPRRVRH 220 P R+ R DS RR P P RP +SSG ++ R Sbjct: 492 PMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSR 551 Query: 221 DSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTY 280 RR+R +S SS R SP R+ S ++ R+R S + +Y Sbjct: 552 SRSRSRSRRRSRTRTSSSSSSR-----SPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSY 606 Query: 281 SLPR 284 S R Sbjct: 607 SSTR 610 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 53.1 bits (126), Expect = 7e-07 Identities = 78/321 (24%), Positives = 109/321 (33%), Gaps = 42/321 (13%) Query: 123 TPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRH 182 TP ++P + G PSP K TP +P + PSP +GA +PP Sbjct: 1197 TPAATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGLATPSP-KGAPTTPAATPPSP--- 1251 Query: 183 DSSDTSPPRRARHDSPDPSPPR------RPQHNSSGASPRRVRHDSPDPSPPRRARHGSS 236 +PP + P +PP P H + +P V SP P G+ Sbjct: 1252 KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA-PNPAVVTPPSPKGGPATSPPKGAP 1310 Query: 237 DISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASS 296 +P SP S T SP P + + P +K G P SS Sbjct: 1311 ---TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG--PTTPSS 1365 Query: 297 KTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDL 356 K P + SH P ++PP K+ + KGD L Sbjct: 1366 KEGPTPPAATPSHKG---------GPAMTPPSPKRGPAI------PSPKGDPTSPAVIPL 1410 Query: 357 SSPRHKQSPGHQD-----SDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSD-----L 406 S + +P ++ S DL+PP P S P+ T SS D + Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV 1470 Query: 407 SPPRRSQPPGKKAAHMYSGAK 427 +PP +PP K S K Sbjct: 1471 TPPSPKEPPAPKQVATSSSPK 1491 >gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo sapiens] Length = 929 Score = 52.4 bits (124), Expect = 1e-06 Identities = 101/501 (20%), Positives = 167/501 (33%), Gaps = 99/501 (19%) Query: 124 PDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDS-DTSPPRRIRH 182 P + P + TP + SP+ A+ SP+R + S + P R + Sbjct: 258 PTAKPLETKSFTPKTKTKTSSPGQKTKSPKTAQSPAMVGSPIRSPKTVSKEKKSPGRSKS 317 Query: 183 DSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDS---------PDP------SP 227 S SP + H P P P S ++ ++ PD + Sbjct: 318 PKSPKSP-KVTTHIPQTPVRPETPNRTPSATLSEKISKETIQVKQIQTPPDAGKLNSENQ 376 Query: 228 PRRAR------HGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRA--RHDSPDLA-PNV 278 P++A S D R PD + GS + + R P+ P Sbjct: 377 PKKAVVADKTIEASIDAVIARACAEREPDPFEFSSGSESEGDIFTSPKRISGPECTTPKA 436 Query: 279 TYSLPR-TKSGKAPERASSKTSPH---W-----------KESGASHLSFPKNSKYEYDPD 323 + S TKSG P S TS W K + + P N Y P Sbjct: 437 STSANNFTKSGSTPLPLSGGTSSSDNSWTMDASIDEVVRKAKLGTPSNMPPNFPYISSPS 496 Query: 324 ISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRH 383 +SPP + + +K +L S + +K +L + K+ + R R Sbjct: 497 VSPPTPEPLHKVYEEKTKLPSSVEVKKKLKKELKTKMKKKE-------------KQRDRE 543 Query: 384 RSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELK 443 R D + + + + K + D R ++ P K + LK Sbjct: 544 REKDKNKDKSKEKDKVKEKEKDKETGRETKYPWK----------------------EFLK 581 Query: 444 EQDQETMAFE-AEFQYAETVFRDKSGRKRNLK---LERLEQRRKAEKDSERDELYAQWGK 499 E++ + F+ EF+ + + K G R K ++ + R K +KD ++ E K Sbjct: 582 EEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDK 641 Query: 500 GLA-QSRQQQQNVEDAMKEMQKPLARYIDDEDLDRML------------------REQER 540 G + + + KE+ PL + ML +E+E+ Sbjct: 642 GREDKMKAPAPPLVLPPKELALPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEK 701 Query: 541 EGDPMANFIKKNKAKENKNKK 561 + D KK K KE K K+ Sbjct: 702 KKDKKEKKKKKEKEKEKKEKE 722 Score = 42.7 bits (99), Expect = 0.001 Identities = 72/364 (19%), Positives = 123/364 (33%), Gaps = 64/364 (17%) Query: 162 PSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHD 221 P PL G SD S D+S R+A+ +P PP P +S SP Sbjct: 450 PLPLSGGTSSSDNSWTM----DASIDEVVRKAKLGTPSNMPPNFPYISSPSVSP------ 499 Query: 222 SPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYS 281 P P P + + + S V + + + Q R R D + + Sbjct: 500 -PTPEPLHKVYEEKTKLPSSVEVKKKLKKELKTKMKKKEKQ---RDREREKDKNKDKSKE 555 Query: 282 LPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRK-KQAKSHFGDKK 340 + K + + +T WKE + P K + D+ P K K +K Sbjct: 556 KDKVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEK 615 Query: 341 QLDSKGDCQKAT-DSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRT 399 D K D +K D D + G +D +PP P +L+ P T Sbjct: 616 HKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPPLVLP-----PKELALPLFSPAT 670 Query: 400 KSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYA 459 S + P P K + E++++KE+++ Sbjct: 671 ASRVPAMLPSLLPVLPEK-----------------LFEEKEKVKEKEK------------ 701 Query: 460 ETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQ 519 K ++ E+++K EK+ E+ E + K + R++++ K Sbjct: 702 --------------KKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIKV 747 Query: 520 KPLA 523 +P+A Sbjct: 748 EPVA 751 >gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sapiens] Length = 805 Score = 51.6 bits (122), Expect = 2e-06 Identities = 88/368 (23%), Positives = 123/368 (33%), Gaps = 52/368 (14%) Query: 69 EEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNED--LPSNRHFRHDTPDS 126 E E DGD V P E + + K K G + S + S Sbjct: 470 EAREADGD---VVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSS 526 Query: 127 SPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSD 186 + V + S R + SP+R + + SP AR S RRI+ +S+ Sbjct: 527 TSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNR 586 Query: 187 TSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRR--- 243 R R S S R + N SP R R S S RR S S RR Sbjct: 587 ARVKIRDRRRSNRNSIERERRRN---RSPSRERRRSRSRSRDRRTNRASRSRSRDRRKID 643 Query: 244 -VHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHW 302 N S + G + Q+ ++ R S D R K K ER K Sbjct: 644 DQRGNLSGNSHKHKGEAKEQERKKERSRSID--------KDRKKKDKEREREQDKRKEKQ 695 Query: 303 KESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQL-------DSKGDCQKATDSD 355 K K+ K+ D RK++++ F + DS+ D +K+T D Sbjct: 696 KRE-------EKDFKFSSQDD-RLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKD 747 Query: 356 LSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPP 415 S H SDS RSS + ++ K S +SQ Sbjct: 748 --------SKKHSGSDSS---------GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRS 790 Query: 416 GKKAAHMY 423 GKKA+ + Sbjct: 791 GKKASRKH 798 Score = 42.7 bits (99), Expect = 0.001 Identities = 54/237 (22%), Positives = 97/237 (40%), Gaps = 41/237 (17%) Query: 328 RKKQAKSHFGDKKQLDSKGDCQ-KATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRH-RS 385 ++KQ +S G S + + +T S +SS + S G + S S P+ + RH RS Sbjct: 502 KEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRS 561 Query: 386 SDSDLSPPRRRQRTKSSDSDLSPPR-RSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKE 444 + R R R+ S + R R + ++ ++ S I+RE++ + Sbjct: 562 RSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNS----------IERERRRNRS 611 Query: 445 QDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQS 504 +E R +S +R + R R + + D +R L K ++ Sbjct: 612 PSRERRRS-----------RSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEA 660 Query: 505 RQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKK 561 ++Q E +K +R I D+D + +E+ERE D K K K+ + +K Sbjct: 661 KEQ---------ERKKERSRSI-DKDRKKKDKEREREQD-------KRKEKQKREEK 700 Score = 32.0 bits (71), Expect = 1.7 Identities = 53/264 (20%), Positives = 99/264 (37%), Gaps = 21/264 (7%) Query: 163 SPLRGARHDSDT-SPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHD 221 S L D D + +R ++++ P++ H + R +SSG+S R Sbjct: 467 SLLEAREADGDVVNEKKRTPNETTSVLEPKK-EHKEKEKQGRSRSGSSSSGSSSSNSRTS 525 Query: 222 SPDP-------SPPRRARHGSSDISSPRRVHNNSPDTS-----RRTLGSSDTQQLR---- 265 S S + SS SSP+R +S S RR+ S +++++ Sbjct: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESN 585 Query: 266 RARHDSPDLAPNVTYSLPR-TKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDI 324 RAR D + S+ R + ++P R ++ ++ + S ++ D Sbjct: 586 RARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQ 645 Query: 325 SPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRP-RH 383 + H G+ K+ + K + ++ D D + K+ QD + + + Sbjct: 646 RGNLSGNSHKHKGEAKEQERKKERSRSIDKD-RKKKDKEREREQDKRKEKQKREEKDFKF 704 Query: 384 RSSDSDLSPPRRRQRTKSSDSDLS 407 S D L R +RT S +S Sbjct: 705 SSQDDRLKRKRESERTFSRSGSIS 728 >gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sapiens] Length = 805 Score = 51.6 bits (122), Expect = 2e-06 Identities = 88/368 (23%), Positives = 123/368 (33%), Gaps = 52/368 (14%) Query: 69 EEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNED--LPSNRHFRHDTPDS 126 E E DGD V P E + + K K G + S + S Sbjct: 470 EAREADGD---VVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSS 526 Query: 127 SPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSD 186 + V + S R + SP+R + + SP AR S RRI+ +S+ Sbjct: 527 TSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNR 586 Query: 187 TSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRR--- 243 R R S S R + N SP R R S S RR S S RR Sbjct: 587 ARVKIRDRRRSNRNSIERERRRN---RSPSRERRRSRSRSRDRRTNRASRSRSRDRRKID 643 Query: 244 -VHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHW 302 N S + G + Q+ ++ R S D R K K ER K Sbjct: 644 DQRGNLSGNSHKHKGEAKEQERKKERSRSID--------KDRKKKDKEREREQDKRKEKQ 695 Query: 303 KESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQL-------DSKGDCQKATDSD 355 K K+ K+ D RK++++ F + DS+ D +K+T D Sbjct: 696 KRE-------EKDFKFSSQDD-RLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKD 747 Query: 356 LSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPP 415 S H SDS RSS + ++ K S +SQ Sbjct: 748 --------SKKHSGSDSS---------GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRS 790 Query: 416 GKKAAHMY 423 GKKA+ + Sbjct: 791 GKKASRKH 798 Score = 42.7 bits (99), Expect = 0.001 Identities = 54/237 (22%), Positives = 97/237 (40%), Gaps = 41/237 (17%) Query: 328 RKKQAKSHFGDKKQLDSKGDCQ-KATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRH-RS 385 ++KQ +S G S + + +T S +SS + S G + S S P+ + RH RS Sbjct: 502 KEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRS 561 Query: 386 SDSDLSPPRRRQRTKSSDSDLSPPR-RSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKE 444 + R R R+ S + R R + ++ ++ S I+RE++ + Sbjct: 562 RSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNS----------IERERRRNRS 611 Query: 445 QDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQS 504 +E R +S +R + R R + + D +R L K ++ Sbjct: 612 PSRERRRS-----------RSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEA 660 Query: 505 RQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKK 561 ++Q E +K +R I D+D + +E+ERE D K K K+ + +K Sbjct: 661 KEQ---------ERKKERSRSI-DKDRKKKDKEREREQD-------KRKEKQKREEK 700 Score = 32.0 bits (71), Expect = 1.7 Identities = 53/264 (20%), Positives = 99/264 (37%), Gaps = 21/264 (7%) Query: 163 SPLRGARHDSDT-SPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHD 221 S L D D + +R ++++ P++ H + R +SSG+S R Sbjct: 467 SLLEAREADGDVVNEKKRTPNETTSVLEPKK-EHKEKEKQGRSRSGSSSSGSSSSNSRTS 525 Query: 222 SPDP-------SPPRRARHGSSDISSPRRVHNNSPDTS-----RRTLGSSDTQQLR---- 265 S S + SS SSP+R +S S RR+ S +++++ Sbjct: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESN 585 Query: 266 RARHDSPDLAPNVTYSLPR-TKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDI 324 RAR D + S+ R + ++P R ++ ++ + S ++ D Sbjct: 586 RARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQ 645 Query: 325 SPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRP-RH 383 + H G+ K+ + K + ++ D D + K+ QD + + + Sbjct: 646 RGNLSGNSHKHKGEAKEQERKKERSRSIDKD-RKKKDKEREREQDKRKEKQKREEKDFKF 704 Query: 384 RSSDSDLSPPRRRQRTKSSDSDLS 407 S D L R +RT S +S Sbjct: 705 SSQDDRLKRKRESERTFSRSGSIS 728 >gi|168229156 NFKB activating protein [Homo sapiens] Length = 415 Score = 50.8 bits (120), Expect = 4e-06 Identities = 84/359 (23%), Positives = 134/359 (37%), Gaps = 40/359 (11%) Query: 201 SPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSD 260 S R P +SG+ RR R S P P + AR SPR + S SR + Sbjct: 5 SGSRSPDREASGSGGRR-RSSSKSPKPSKSAR-------SPRGRRSRSHSCSRSGDRNGL 56 Query: 261 TQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEY 320 T QL S R +S ++ R+ S+ P S + F S Y Sbjct: 57 THQLGGLSQGS------------RNQSYRSRSRSRSRERP----SAPRGIPFASASSSVY 100 Query: 321 DPDISPPRKKQAK-SHFGDKKQLDS---KGDCQKATDSDLSSPR-HKQSPGHQDSDSDLS 375 S P DK++ +S K ++ +L +P SP + + DSD Sbjct: 101 YGSYSRPYGSDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEH 160 Query: 376 PPRNRPRHRSSDSDLSPPRRRQRTKSSDS-DLSPPRRSQPPGKKAAHMYSGAKTGLVLTD 434 P + S + S ++ KSS S + S RR + K+ YS +D Sbjct: 161 TPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSD----SD 216 Query: 435 IQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELY 494 E + ++D + A +A+ + + R K +K+ K R E + K+S+ + L Sbjct: 217 SDSE-TDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLE 275 Query: 495 AQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNK 553 W + R + + D + DD+ L+ EG MA ++K K Sbjct: 276 NPW-----KDRTKAEEPSDLIGPEAPKTLTSQDDKPLNYGHALLPGEGAAMAEYVKAGK 329 >gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] Length = 320 Score = 50.8 bits (120), Expect = 4e-06 Identities = 59/227 (25%), Positives = 92/227 (40%), Gaps = 43/227 (18%) Query: 11 EYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA------ISTT 64 EY++R S + E GRK++K R K G + D + +S Sbjct: 113 EYIEREESDGEY-----DEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKY 167 Query: 65 KLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTP 124 KL+++E+EDD DL E + K+ RS +K + + H R + Sbjct: 168 KLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSR-----------SSHSRSSSR 216 Query: 125 DSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDT------SPPR 178 SSP R S + R + S R+R + + S RG++ S + S PR Sbjct: 217 SSSPSSSR------SRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR 270 Query: 179 RIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSG-ASPRRVRHDSPD 224 + + SS +SP R + R + +SSG RR R SP+ Sbjct: 271 KRSYSSSSSSPERNRKRS--------RSRSSSSGDRKKRRTRSRSPE 309 Score = 37.7 bits (86), Expect = 0.032 Identities = 37/134 (27%), Positives = 57/134 (42%), Gaps = 6/134 (4%) Query: 270 DSPDLAP-NVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPR 328 D DL+ N+ S + K R S S +S S P +S+ Sbjct: 176 DDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS 235 Query: 329 KKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQD-SDSDLSPPRNRPRHRSSD 387 Q++S +++ S+G +++ S R SP + S S SP RNR R RS Sbjct: 236 SSQSRSRSSSRERSRSRGSKSRSSSR---SHRGSSSPRKRSYSSSSSSPERNRKRSRSRS 292 Query: 388 SDLSPPRRRQRTKS 401 S S R+++RT+S Sbjct: 293 SS-SGDRKKRRTRS 305 Score = 34.3 bits (77), Expect = 0.35 Identities = 40/201 (19%), Positives = 70/201 (34%), Gaps = 9/201 (4%) Query: 314 KNSKYEYDPDISPPRKKQAKSHFGDK---KQLDSKGDCQKATDSDLSSPRHKQSPGHQDS 370 + S EYD + +KK G K+++ K + D D ++K + Sbjct: 118 EESDGEYD-EFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDED 176 Query: 371 DSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGL 430 D+DLS N DS+ RR R+KS S RS P + S +++ Sbjct: 177 DADLSK-YNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS 235 Query: 431 VLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSER 490 R + + + + + + + + S RKR+ R ++ R Sbjct: 236 SSQSRSRSSSRERSRSRGSKSRSSSRSHRGS----SSPRKRSYSSSSSSPERNRKRSRSR 291 Query: 491 DELYAQWGKGLAQSRQQQQNV 511 K +SR + V Sbjct: 292 SSSSGDRKKRRTRSRSPESQV 312 Score = 32.7 bits (73), Expect = 1.0 Identities = 34/138 (24%), Positives = 54/138 (39%), Gaps = 11/138 (7%) Query: 292 ERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKA 351 E S+K + + S S ++S P S R + ++S Q S+ ++ Sbjct: 190 EEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSR-SRSRSSSSSQSRSRSSSRER 248 Query: 352 TDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRS-SDSDLSPPRRRQRTKSSDSDLSPPR 410 + S S R S H+ S S PR RS S S SP R R+R++S S + Sbjct: 249 SRSRGSKSR-SSSRSHRGSSS--------PRKRSYSSSSSSPERNRKRSRSRSSSSGDRK 299 Query: 411 RSQPPGKKAAHMYSGAKT 428 + + + G T Sbjct: 300 KRRTRSRSPESQVIGENT 317 Score = 31.6 bits (70), Expect = 2.3 Identities = 34/116 (29%), Positives = 49/116 (42%), Gaps = 7/116 (6%) Query: 178 RRIRHDSSDTSPPRRARHDSPDPSPPR-RPQHNSSGASPRRVRHDSPDPSPPRRARHGSS 236 RR R S + +R SP S R R + SS +S R R S + S R+R S Sbjct: 200 RRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERS---RSRGSKS 256 Query: 237 DISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPE 292 SS R H S +R+ SS + R + + + RT+S ++PE Sbjct: 257 RSSS--RSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRS-RSPE 309 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 50.4 bits (119), Expect = 5e-06 Identities = 70/368 (19%), Positives = 147/368 (39%), Gaps = 54/368 (14%) Query: 232 RHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAP 291 R SS++++P + ++ P R+ RR +AP + Y L + A Sbjct: 216 REYSSELNAPSQESDSHP---RKKKKEKKEDIFRRF-----PVAPLIPYPLITKEDINAI 267 Query: 292 ERASSKTSPHWKESGA-----SHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKG 346 E K +E L K K + +I R+++ + ++++ + + Sbjct: 268 EMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERER 327 Query: 347 DCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSD------SDLSPPRRRQRTK 400 + ++ + + R ++ +D D R+R R R D SD + R R R K Sbjct: 328 EREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREK 387 Query: 401 SSDSDLSPPR-------RSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFE 453 S D + R R + ++ + D +R+++E +E E E Sbjct: 388 SRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLE 447 Query: 454 AEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVED 513 + + E +++ R +N ++ ++ R+ EK++ER+E ++++ + Sbjct: 448 RKLREKEAAYQE---RLKNWEIRERKKTREYEKEAEREE-------------ERRREMAK 491 Query: 514 AMKEMQKPLARYIDDED---------LDRMLREQEREGDPMANFIKKNKAKENKNKKVRP 564 K +++ L Y DD D L + LR++E+E M + K ++ + +++R Sbjct: 492 EAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKE---MEADERDRKREKEELEEIRQ 548 Query: 565 RYSGPAPP 572 R P Sbjct: 549 RLLAEGHP 556 Score = 43.5 bits (101), Expect = 6e-04 Identities = 48/269 (17%), Positives = 103/269 (38%), Gaps = 44/269 (16%) Query: 328 RKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSD 387 R+++ + +++ + D + + D R + ++ SD + R+R R +S D Sbjct: 331 REREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRD 390 Query: 388 SDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQ 447 + R R+R + + + R + ++ D +R+++E +E Sbjct: 391 REREREREREREREREREREREREREREREREREREK---------DKKRDREEDEEDAY 441 Query: 448 ETMAFEAEFQYAETVFRD----------KSGRKRNLKLERLEQRRKA------------- 484 E E + + E +++ K R+ + ER E+RR+ Sbjct: 442 ERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLE 501 Query: 485 EKDSERDELYAQWGKGL------------AQSRQQQQNVEDAMKEMQKPLARYIDDEDLD 532 + D +RD+ G L A R +++ E+ + Q+ LA D D + Sbjct: 502 DYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAE 561 Query: 533 RMLREQEREGDPMANFIKKNKAKENKNKK 561 EQE E ++ +++E + +K Sbjct: 562 LQRMEQEAERRRQPQIKQEPESEEEEEEK 590 >gi|16445033 ACRC protein [Homo sapiens] Length = 691 Score = 50.4 bits (119), Expect = 5e-06 Identities = 68/324 (20%), Positives = 117/324 (36%), Gaps = 37/324 (11%) Query: 110 NEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGAR 169 + + P + D PD + D S + D+ P + D PD Sbjct: 175 DSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPD-------- 226 Query: 170 HDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPR 229 D+S + DSSD S A DS D S + S A P DS P Sbjct: 227 ---DSSDDSDVPDDSSDDS---EAPDDSSDDSEAPDDSSDDSEA-PDDSSDDSEAPDDSS 279 Query: 230 RARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSL--PRTKS 287 S D S ++S D S SD + + D D+ + + L P Sbjct: 280 DDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAE 339 Query: 288 GKAPE-----------RASSKTSPHWKESGASHLSFPKN-SKYEYDPDISPP-RKKQAKS 334 E A++ S H A +N SK DP+ +P +++ + Sbjct: 340 DLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPT 399 Query: 335 HFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPR 394 ++ G + T + + PR +Q+ + + + PPR R ++ ++ P Sbjct: 400 EEEPAPVVEQSGKRKSKTKTIVEPPRKRQT----KTKNIVEPPRKR---QTKTKNIVEPL 452 Query: 395 RRQRTKSSDSDLSPPRRSQPPGKK 418 R+++ K+ + ++P + + P KK Sbjct: 453 RKRKAKTKNVSVTPGHKKRGPSKK 476 Score = 33.5 bits (75), Expect = 0.60 Identities = 55/235 (23%), Positives = 81/235 (34%), Gaps = 25/235 (10%) Query: 143 DRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSP 202 D +D + + D D S D +P D+SD S A D+ D S Sbjct: 126 DDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPD-----DNSDDS---EAPDDNSDDS- 176 Query: 203 PRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQ 262 P NS + V D+ D S + S D S V ++ D S SSD Sbjct: 177 -EAPDDNSDDSD---VPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDS 232 Query: 263 QLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDP 322 + D + AP+ + + +AP+ +S + S S + E Sbjct: 233 DVPDDSSDDSE-APDDS-----SDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASD 286 Query: 323 DISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPP 377 D S S D DS+ K+ DSD+ + S D+ DL P Sbjct: 287 DSSDD------SEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVP 335 Score = 31.2 bits (69), Expect = 3.0 Identities = 79/403 (19%), Positives = 133/403 (33%), Gaps = 58/403 (14%) Query: 170 HDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPR 229 +D D + D+SD S A D+ D S P NS + D + Sbjct: 128 NDDDNGNDLEVPDDNSDDS---EAPDDNSDDS--EAPDDNSDDSEAPDDNSDDSEAPDDN 182 Query: 230 RARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGK 289 D +S +NS D+S SD + D PD + Sbjct: 183 SDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPD---------DSSDDSD 233 Query: 290 APERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQ 349 P+ +S + P +S D P S D DS+ Sbjct: 234 VPDDSSDDSEA------------PDDSS----DDSEAPDDSSDDSEAPDDSSDDSEAPDD 277 Query: 350 KATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPP 409 + DS+ S S DS D P ++ S DSD+ KS DSD+ P Sbjct: 278 SSDDSEASDDSSDDSEASDDSSDDSEAPDDK----SDDSDVP------EDKSDDSDV--P 325 Query: 410 RRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEA-EFQYAETVFRDKSG 468 + + G + +D + + Q + +A E E + + S Sbjct: 326 DDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSD 385 Query: 469 RKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDD 528 + N ++ RK + E + Q GK ++++ ++ P R Sbjct: 386 PEANPEV----SERKLPTEEEPAPVVEQSGKRKSKTK----------TIVEPPRKRQTKT 431 Query: 529 EDLDRMLREQEREGDPMANFIKKNKAKENKNKKVRPRYSGPAP 571 +++ R+++ + + ++K KAK KN V P + P Sbjct: 432 KNIVEPPRKRQTKTKNIVEPLRKRKAK-TKNVSVTPGHKKRGP 473 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 50.4 bits (119), Expect = 5e-06 Identities = 72/389 (18%), Positives = 140/389 (35%), Gaps = 37/389 (9%) Query: 180 IRHDSSDTSPPRRARHDSPDP-SPPRRPQHNSS--GASPRRVRHDS------PDPSPP-- 228 +R +T P R A + D S PR N G P ++ H + P+ +P Sbjct: 212 VRMAGDETQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAA 271 Query: 229 --------RRARHGSSDIS---------SPRRVHNNSPDTSRRTLGSSDTQQLRRARHDS 271 +R R S IS S R S +R SS RR R S Sbjct: 272 AKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQS 331 Query: 272 PDLAPNVTYSLPRTKS---GKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPR 328 + + S R K K+P + SK+ K SH + E + + Sbjct: 332 KHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK 391 Query: 329 KKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDS 388 +K + +K+ + + + K D D R K ++ D + + + R + Sbjct: 392 EKDREKEREREKEREKEKERGKNKDRD--KEREKDREKDKEKDREREREKEHEKDRDKEK 449 Query: 389 DLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQE 448 + + ++R K ++ R+ + Y+ ++ + +R ++ Sbjct: 450 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSP 509 Query: 449 TMAFEAEFQYAETV---FRDKSGRKRNLKLERLEQRRKAEKD-SERDELYAQWGKGLAQS 504 + + + + + R+K +KR + + + +RR+ E+ S R + GK + Sbjct: 510 RTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEK 569 Query: 505 RQQQQNVEDAMKEMQKPLARYIDDEDLDR 533 ++ KE +++ +DD+D R Sbjct: 570 NSTSLKEKEHNKEPDSSVSKEVDDKDAPR 598 Score = 37.0 bits (84), Expect = 0.054 Identities = 43/204 (21%), Positives = 87/204 (42%), Gaps = 53/204 (25%) Query: 358 SPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGK 417 S H +S S S R++ +HRS + S R++ R RRS+ P K Sbjct: 308 SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDR-----------RRSKSPHK 356 Query: 418 KAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLER 477 K + K+ R + +++ ++T R+K K +K + Sbjct: 357 KRSKSRERRKS--------RSRSHSRDKRKDT--------------REKIKEKERVKEKD 394 Query: 478 LEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLRE 537 E+ R+ EK+ E+++ + GK + ++++++ E D++ DR E Sbjct: 395 REKEREREKEREKEK---ERGKNKDRDKEREKDREK--------------DKEKDR---E 434 Query: 538 QEREGDPMANFIKKNKAKENKNKK 561 +ERE + + K+ + +++K K+ Sbjct: 435 REREKEHEKDRDKEKEKEQDKEKE 458 Score = 36.6 bits (83), Expect = 0.070 Identities = 43/197 (21%), Positives = 69/197 (35%), Gaps = 15/197 (7%) Query: 116 NRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTS 175 +R R S R R T + K+R D R R + RG D D Sbjct: 361 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 420 Query: 176 PPR-RIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHG 234 + R + D R H+ + Q R + +++R Sbjct: 421 REKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR-- 478 Query: 235 SSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERA 294 +P R +N SRR+ SS ++ RR+R S +P + ++ R KS ++P Sbjct: 479 -----TPPRSYN----ASRRSRSSSRERRRRRSR--SSSRSPRTSKTIKR-KSSRSPSPR 526 Query: 295 SSKTSPHWKESGASHLS 311 S +E H+S Sbjct: 527 SRNKKDKKREKERDHIS 543 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.128 0.378 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,206,115 Number of Sequences: 37866 Number of extensions: 1929358 Number of successful extensions: 14979 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 145 Number of HSP's successfully gapped in prelim test: 1068 Number of HSP's that attempted gapping in prelim test: 10012 Number of HSP's gapped (non-prelim): 4053 length of query: 619 length of database: 18,247,518 effective HSP length: 108 effective length of query: 511 effective length of database: 14,157,990 effective search space: 7234732890 effective search space used: 7234732890 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.