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Search of human proteins with 14249338
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14249338 BUD13 homolog isoform 1 [Homo sapiens]
(619 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14249338 BUD13 homolog isoform 1 [Homo sapiens] 1276 0.0
gi|229577273 BUD13 homolog isoform 2 [Homo sapiens] 615 e-176
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 76 1e-13
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 76 1e-13
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 74 4e-13
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap... 68 2e-11
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 68 3e-11
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 65 1e-10
gi|217330641 IWS1 homolog [Homo sapiens] 64 5e-10
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 62 2e-09
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 59 1e-08
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 57 4e-08
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 56 9e-08
gi|50962882 G patch domain containing 8 [Homo sapiens] 56 9e-08
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 56 9e-08
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 55 1e-07
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 55 2e-07
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 54 4e-07
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 54 6e-07
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 53 7e-07
gi|50083281 KIAA1853 protein [Homo sapiens] 53 7e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni... 53 7e-07
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 52 1e-06
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 52 2e-06
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 52 2e-06
gi|168229156 NFKB activating protein [Homo sapiens] 51 4e-06
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 51 4e-06
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 50 5e-06
gi|16445033 ACRC protein [Homo sapiens] 50 5e-06
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 50 5e-06
>gi|14249338 BUD13 homolog isoform 1 [Homo sapiens]
Length = 619
Score = 1276 bits (3302), Expect = 0.0
Identities = 619/619 (100%), Positives = 619/619 (100%)
Query: 1 MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA 60
MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA
Sbjct: 1 MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA 60
Query: 61 ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120
ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR
Sbjct: 61 ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120
Query: 121 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI 180
HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI
Sbjct: 121 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI 180
Query: 181 RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISS 240
RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISS
Sbjct: 181 RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISS 240
Query: 241 PRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSP 300
PRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSP
Sbjct: 241 PRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSP 300
Query: 301 HWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPR 360
HWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPR
Sbjct: 301 HWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPR 360
Query: 361 HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAA 420
HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAA
Sbjct: 361 HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAA 420
Query: 421 HMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQ 480
HMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQ
Sbjct: 421 HMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQ 480
Query: 481 RRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQER 540
RRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQER
Sbjct: 481 RRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQER 540
Query: 541 EGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFAR 600
EGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFAR
Sbjct: 541 EGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFAR 600
Query: 601 LASKKAVEELAYKWSVEDM 619
LASKKAVEELAYKWSVEDM
Sbjct: 601 LASKKAVEELAYKWSVEDM 619
>gi|229577273 BUD13 homolog isoform 2 [Homo sapiens]
Length = 485
Score = 615 bits (1586), Expect = e-176
Identities = 325/438 (74%), Positives = 342/438 (78%), Gaps = 64/438 (14%)
Query: 184 SSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRR 243
+ D R RHD+PD +SPRRVRH +PDPSP R+ RH + D SPRR
Sbjct: 110 NEDLPSNRHFRHDTPD-------------SSPRRVRHGTPDPSP-RKDRHDTPD-PSPRR 154
Query: 244 VHNNSPDTS--RRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPH 301
+++PD S R SDT RR RHDS D +P
Sbjct: 155 ARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSP------------------------- 189
Query: 302 WKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRH 361
P+ ++++ PD SPPR+ Q +S GDCQKATDSDLSSPRH
Sbjct: 190 -----------PRRARHD-SPDPSPPRRPQH----------NSSGDCQKATDSDLSSPRH 227
Query: 362 KQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAH 421
KQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAH
Sbjct: 228 KQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAH 287
Query: 422 MYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQR 481
MYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQR
Sbjct: 288 MYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQR 347
Query: 482 RKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQERE 541
RKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQERE
Sbjct: 348 RKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQERE 407
Query: 542 GDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARL 601
GDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARL
Sbjct: 408 GDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARL 467
Query: 602 ASKKAVEELAYKWSVEDM 619
ASKKAVEELAYKWSVEDM
Sbjct: 468 ASKKAVEELAYKWSVEDM 485
Score = 459 bits (1182), Expect = e-129
Identities = 255/442 (57%), Positives = 292/442 (66%), Gaps = 25/442 (5%)
Query: 1 MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA 60
MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA
Sbjct: 1 MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA 60
Query: 61 ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120
ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR
Sbjct: 61 ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120
Query: 121 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI 180
HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI
Sbjct: 121 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI 180
Query: 181 RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARH--GSSDI 238
RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSG + D P + H SD+
Sbjct: 181 RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDL 240
Query: 239 SSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASS-- 296
S PR N P S ++ +R + DL+P P K+ A +
Sbjct: 241 SPPR----NRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGL 296
Query: 297 ------KTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQK 350
+ KE ++F ++++Y + R K + ++L+ + +K
Sbjct: 297 VLTDIQREQQELKEQDQETMAF--EAEFQYAETVF--RDKSGRKRNLKLERLEQRRKAEK 352
Query: 351 ATDSD-LSSPRHK---QSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSD--- 403
++ D L + K QS Q + D +P R D + R++ + D
Sbjct: 353 DSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMA 412
Query: 404 SDLSPPRRSQPPGKKAAHMYSG 425
+ + + + KK YSG
Sbjct: 413 NFIKKNKAKENKNKKVRPRYSG 434
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 75.9 bits (185), Expect = 1e-13
Identities = 88/294 (29%), Positives = 115/294 (39%), Gaps = 45/294 (15%)
Query: 114 PSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSD 173
P+ R R TP + RR R TP R+ R + P+ RR+R SP+R R
Sbjct: 589 PARRRSRSRTP--TRRRSRSRTP---ARRGRSRSRTPARRRSR----TRSPVR--RRSRS 637
Query: 174 TSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARH 233
SP RR S T P RR R S +P RR + S + R R S P AR
Sbjct: 638 RSPARRSGRSRSRT-PARRGR--SRSRTPARRGRSRSRTPARRSGRSRSRTP-----ARR 689
Query: 234 GSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPER 293
G S +PRR + S RR S T Q R S + S R++S +PE
Sbjct: 690 GRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEM 749
Query: 294 ASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATD 353
S+ S S +S PR K AKS ++ L C K
Sbjct: 750 KKSRISSRRSRS------------------LSSPRSK-AKSRLSLRRSLSGSSPCPK--Q 788
Query: 354 SDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLS 407
+ PR +S Q +PPR RS S PP+++ +T S S S
Sbjct: 789 KSQTPPRRSRSGSSQPKAKSRTPPR-----RSRSSSSPPPKQKSKTPSRQSHSS 837
Score = 68.9 bits (167), Expect = 1e-11
Identities = 142/643 (22%), Positives = 218/643 (33%), Gaps = 111/643 (17%)
Query: 28 SESGRKRRKKR-PKPGGAGGKGMRIVDDDVSWTAISTTKLEKEEEEDDGDLPVVAEFVDE 86
SES K+RK R P P K R D + STT K A D
Sbjct: 220 SESESKKRKHRSPTP-----KSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDT 274
Query: 87 RPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRV---RHGTPDPSPR-- 141
+ A + L G + S R D P S P R +P+ + +
Sbjct: 275 SRSRSRSAAAKTHTTA---LAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQP 331
Query: 142 --------KDRHDT----PDPSPRRARH--DTPDPSPLRGARHDSDTSP----------- 176
KD+ + P PSP R+ + P P+PL RH P
Sbjct: 332 SSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPV 391
Query: 177 -PRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGS 235
P + D SPP+ SP + PQ +SS +SP P P P + +RH S
Sbjct: 392 NPPSEASPTRDRSPPK---------SPEKLPQSSSSESSP-------PSPQPTKVSRHAS 435
Query: 236 SDISSPR--------RVHNNSPDTSRRTLG-------SSDTQQLRRARHDSPDLAPNVTY 280
S SP+ R ++SP + R+ G S T R R SP T
Sbjct: 436 SSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSP-----ATA 490
Query: 281 SLPRTKSGKAPERASSKT-SPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDK 339
R++S +R S++ SP W+ S ++ S SP R ++S
Sbjct: 491 KRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRS----- 545
Query: 340 KQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQR- 398
+ +G + A H +SP + +P R R R RS +P RRR R
Sbjct: 546 RNTQRRGRSRSAR----RGRSHSRSPATRGRSRSRTPAR-RGRSRSR----TPARRRSRS 596
Query: 399 ---TKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAE 455
T+ +P RR + + A S ++ + R + +
Sbjct: 597 RTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRG 656
Query: 456 FQYAETVFR----------DKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSR 505
+ T R +SGR R+ R + R R + +G + SR
Sbjct: 657 RSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSR 716
Query: 506 QQQQNVEDAMKEMQKPLARYIDDEDLDRMLRE--QEREGDPMANFIKKNKAKENKNKKVR 563
Q+ +K +R E + R + + ++K +R
Sbjct: 717 TPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLR 776
Query: 564 PRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARLASKKA 606
SG +P P + + P R RS + K +R +++
Sbjct: 777 RSLSGSSPCPKQKSQTPPRR----SRSGSSQPKAKSRTPPRRS 815
Score = 61.6 bits (148), Expect = 2e-09
Identities = 89/374 (23%), Positives = 138/374 (36%), Gaps = 56/374 (14%)
Query: 70 EEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPR 129
+EE G P V E K+ E R++ G ++ F P R
Sbjct: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAF------GISDSYVDGSSF---DPQRRAR 158
Query: 130 RVRHGTPDP--------SPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIR 181
+ P+P R TP ++ + D RG R S++S PRR R
Sbjct: 159 EAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKD-------RGRR--SESSSPRRER 209
Query: 182 HDSS------DTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGS 235
SS S ++ +H SP P R+ + +R R S P+P R H S
Sbjct: 210 KKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDK------KRKRSRSTTPAPKSRRAHRS 263
Query: 236 SDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERAS 295
+ S +S DTSR S ++ H + + + + R G AP
Sbjct: 264 TSADSA-----SSSDTSR-----SRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEP 313
Query: 296 SKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSD 355
TS S + P + + D D +K+++ + + S G + +
Sbjct: 314 GTTSTQRPSSPETATKQPSSPYEDKDKD----KKEKSATRPSPSPERSSTGP-EPPAPTP 368
Query: 356 LSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQR-TKSSDSDLSPPRRSQP 414
L + RH SP + P N P S D SPP+ ++ +SS S+ SPP S
Sbjct: 369 LLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPP--SPQ 426
Query: 415 PGKKAAHMYSGAKT 428
P K + H S ++
Sbjct: 427 PTKVSRHASSSPES 440
Score = 61.6 bits (148), Expect = 2e-09
Identities = 93/331 (28%), Positives = 126/331 (38%), Gaps = 68/331 (20%)
Query: 128 PRRVRHGTPDP------SPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIR 181
PRR R + P +P + H + P P + + TP R S TSP
Sbjct: 812 PRRSRSSSSPPPKQKSKTPSRQSHSSSSPHP-KVKSGTP-------PRQGSITSPQ---A 860
Query: 182 HDSSDTSPPRRARHDSPDPSPPRR--PQHNSSGASPRRV-----------RHDSPDP--- 225
++ S T R SPDP R +H+ SG+SP RV R SP P
Sbjct: 861 NEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVK 920
Query: 226 ---SPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQ--LRRARHD---------S 271
SP +R+ GSS S R +P SR S+ + L R H
Sbjct: 921 AIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVK 980
Query: 272 PDLAPNVTYS-----LPRTKSGKAPE---RASSKTSPHWKESGASHLSFPKNSKYEYDPD 323
P+ P ++S P+ K+ P S P K + S P +
Sbjct: 981 PETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVK 1040
Query: 324 ISPPRKKQAKSHFGDKKQLDSKGDCQKATD--SDLSSPR----HKQSPGHQDSDSDLSPP 377
S P +S+FG L KG Q + D SD SSP H +SP Q S S SP
Sbjct: 1041 SSTP---PGESYFG-VSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQ-SKSQTSPK 1095
Query: 378 RNRPRHRSSDSDLS--PPRRRQRTKSSDSDL 406
R R S ++L+ P R+ R + S S +
Sbjct: 1096 GGRSRSSSPVTELASRSPIRQDRGEFSASPM 1126
Score = 60.8 bits (146), Expect = 3e-09
Identities = 83/317 (26%), Positives = 117/317 (36%), Gaps = 52/317 (16%)
Query: 127 SPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTP---DPSPLRGARHDSDTSPPRRIRHD 183
+P+R R G+ +K TP R+ PS R +SD+SP + +
Sbjct: 1511 TPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAK-- 1568
Query: 184 SSDTSPPRRARH--------DSPDPSPPRRPQHNSSG-------ASPRRVRHDSPDPSP- 227
T P R R DS PRR + SS A+PR P P
Sbjct: 1569 ---TRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPK 1625
Query: 228 -------PRRARHGSSDISSPRRVHNNSPDTSRRTLGSSD----TQQLRRARHDSPDLAP 276
PRR+R GSS + SP+ S T S + ++ RR SP+
Sbjct: 1626 APAPRALPRRSRSGSSS-----KGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPE--- 1677
Query: 277 NVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHF 336
P+TKS P R SS++SP S +PPR +++ S
Sbjct: 1678 ------PKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVS 1731
Query: 337 GDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRR 396
+ S+ ++ + SSPR K + S S R R RS RRR
Sbjct: 1732 SPEPAEKSRSSRRRRS---ASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRR 1788
Query: 397 QRTKSSDSDLSPPRRSQ 413
R+ SS S +RS+
Sbjct: 1789 DRSGSSQSTSRRRQRSR 1805
Score = 57.4 bits (137), Expect = 4e-08
Identities = 98/377 (25%), Positives = 132/377 (35%), Gaps = 68/377 (18%)
Query: 98 RSSAKWKLLGGHNEDLPSNR-HFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPR-RA 155
RS + + G P+ R R TP RR R + P+ R R + P+ R R+
Sbjct: 636 RSRSPARRSGRSRSRTPARRGRSRSRTP---ARRGRSRSRTPARRSGRSRSRTPARRGRS 692
Query: 156 RHDTP------DPSPLRGARHDSDTSPPRRIRHDSSD-------TSPPRRARHDSPDPSP 202
R TP S +R R S T P RR R SS TS R + SP+
Sbjct: 693 RSRTPRRGRSRSRSLVRRGRSHSRT-PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKK 751
Query: 203 PRRPQHNSSGASP------------RRVRHDSPDP-----SPPRRARHGSSDISSPRRVH 245
R S S R + SP P +PPRR+R GSS P+
Sbjct: 752 SRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQ---PKAKS 808
Query: 246 NNSPDTSRRTLGSSDTQQLRR-ARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKE 304
P SR + Q+ + +R +P+ P+ KSG P R S TSP E
Sbjct: 809 RTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH-----PKVKSG-TPPRQGSITSPQANE 862
Query: 305 SGASHLSFPKNSKYEYDPD---------------ISPPRKKQAKSHFGDKKQLDSKGDCQ 349
+ + S +E PD SPPR K + +Q S+
Sbjct: 863 QSVTP---QRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTP----PRQSPSRSSSP 915
Query: 350 KATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPP 409
+ + SPR + G R PR S S S R + S S S P
Sbjct: 916 QPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSP 975
Query: 410 RRSQPPGKKAAHMYSGA 426
P +SG+
Sbjct: 976 DTKVKPETPPRQSHSGS 992
Score = 57.0 bits (136), Expect = 5e-08
Identities = 100/413 (24%), Positives = 148/413 (35%), Gaps = 40/413 (9%)
Query: 1 MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA 60
+++ P K+ +R S A R + R+ R PKP G R
Sbjct: 1730 VSSPEPAEKSRSSRRRRS---ASSPRTKTTSRRGRSPSPKPRGLQRSRSR---------- 1776
Query: 61 ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120
++ EK D ++ R +Q RS + GG S
Sbjct: 1777 ---SRREKTRTTRRRDRSGSSQSTSRR----RQRSRSRSRVTRRRRGGSGYHSRSPARQE 1829
Query: 121 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI 180
S RR R TP P+ RK P+P + P+ R +R + RR
Sbjct: 1830 SSRTSSRRRRGRSRTP-PTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRS 1888
Query: 181 RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISS 240
R S TSP R R S RR + +S S RR R +P P R R S ++
Sbjct: 1889 R---SRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTP---PVTRRRSRSRTPTT 1942
Query: 241 PRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERAS-SKTS 299
RR + +P +RR S RR S +T R+++ R S S+TS
Sbjct: 1943 RRRSRSRTPPVTRRRSRSRTPPVTRRR---SRSRTSPITRRRSRSRTSPVTRRRSRSRTS 1999
Query: 300 PHWKESGASHLS--FPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLS 357
P + S S + S+ P I R+ ++++ +K+ S+ S
Sbjct: 2000 PVTRRRSRSRTSPVTRRRSRSRTPPAIR--RRSRSRTPLLPRKRSRSRSPLAIRRRSRSR 2057
Query: 358 SPRHKQSPGHQDSDSDLSPPRNRPRHRS-SDSDLSPPRRRQRTKSSDSDLSPP 409
+PR + SPP R R S S SD S T++ +PP
Sbjct: 2058 TPRTARG----KRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPP 2106
Score = 54.7 bits (130), Expect = 2e-07
Identities = 83/329 (25%), Positives = 114/329 (34%), Gaps = 58/329 (17%)
Query: 125 DSSPRRVRHGTPDPSPRKDRHDTPDP-----SPRRARHDTPDPSPLRGAR-----HDSDT 174
+SSP H + R+ +P+P +P R R P R AR + +
Sbjct: 1656 ESSPE---HPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASS 1712
Query: 175 SPPRRIRHDSSDTSPPRRARH---DSPDPSPPRRPQHNSSGASPRRV-----RHDSPDPS 226
SP R R +PPR R SP+P+ R AS R R SP P
Sbjct: 1713 SPETRSR------TPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK 1766
Query: 227 P------------------PRRARHGSSDISSPRRVHNNSPD-TSRRTLGSSDTQQLRRA 267
P RR R GSS +S RR + S +RR G S A
Sbjct: 1767 PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPA 1826
Query: 268 RHDSPDLAPNVTYSLPRTKSGKAPERASSKTSP-HWKESGASHLSFPKNSKYEYDPDISP 326
R +S + RT + +R+ S+TSP WK S + P IS
Sbjct: 1827 RQESSRTSSRRRRGRSRTPP-TSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISR 1885
Query: 327 PRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSS 386
R + S ++ + T R + SP + +PP R R RS
Sbjct: 1886 RRSRSRTSPVSRRRS-------RSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSR 1938
Query: 387 DSDLSPPRRRQRTKSSDSDLSPPRRSQPP 415
RRR R+++ R PP
Sbjct: 1939 ---TPTTRRRSRSRTPPVTRRRSRSRTPP 1964
Score = 52.4 bits (124), Expect = 1e-06
Identities = 71/324 (21%), Positives = 121/324 (37%), Gaps = 27/324 (8%)
Query: 126 SSPRRVRHGTPDPSPRKDRHDTPDPSPR-------RARHDTPDPSPLRGARHDSDTSPPR 178
SS RR +P R +P P PR R+R + + R S ++ R
Sbjct: 1741 SSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRR 1800
Query: 179 RIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDI 238
R R S RR P R + + + + RR R +P P+ +R+R +S
Sbjct: 1801 RQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTP-PTSRKRSRSRTSPA 1859
Query: 239 SSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLA-----PNVTYSLPRTKSGKAP-- 291
R SP T RR+ + RR+R + ++ + + R++S +P
Sbjct: 1860 PWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVS 1919
Query: 292 -ERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQK 350
R+ S+T P + S + P ++ R + ++ +
Sbjct: 1920 RRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITR 1979
Query: 351 ATDSDLSSP------RHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDS 404
+SP R + SP + + P R R RS +PP R+R++S +
Sbjct: 1980 RRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSR----TPPAIRRRSRSR-T 2034
Query: 405 DLSPPRRSQPPGKKAAHMYSGAKT 428
L P +RS+ A S ++T
Sbjct: 2035 PLLPRKRSRSRSPLAIRRRSRSRT 2058
Score = 50.8 bits (120), Expect = 4e-06
Identities = 66/251 (26%), Positives = 101/251 (40%), Gaps = 45/251 (17%)
Query: 175 SPPRRIRHDSS-----DTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPR 229
+PPRR R SS +PPRR+R S SPP P+ S +P R H S P P
Sbjct: 792 TPPRRSRSGSSQPKAKSRTPPRRSRSSS---SPP--PKQKSK--TPSRQSHSSSSPHP-- 842
Query: 230 RARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLP--RTKS 287
+ + G + PR+ SP + +++ T Q R SPD P + P + S
Sbjct: 843 KVKSG----TPPRQGSITSPQANEQSV----TPQRRSCFESSPD--PELKSRTPSRHSCS 892
Query: 288 GKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGD 347
G +P R S T P S +S P + + +SH G S+
Sbjct: 893 GSSPPRVKSSTPPRQSPSRSS----------SPQPKVKAIISPRQRSHSGSSSPSPSR-- 940
Query: 348 CQKATDSDLSSPRHKQSPGH-QDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDL 406
+ ++PR +S + +S L P + S D+ + P +++ S
Sbjct: 941 -----VTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISP 995
Query: 407 SPPRRSQ-PPG 416
P ++Q PPG
Sbjct: 996 YPKVKAQTPPG 1006
Score = 50.8 bits (120), Expect = 4e-06
Identities = 68/310 (21%), Positives = 110/310 (35%), Gaps = 48/310 (15%)
Query: 120 RHDTPDSSPRRVRHGTPDPSPRKDRHDTP----DPSPRRARHDTPDPSPLRGARHDSDTS 175
R + +S ++ G P R+ R + D S +RH SP D +
Sbjct: 1416 RERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSP---GMKDIPRT 1472
Query: 176 PPRRIRHDSSDTSPPRRARHDSPDPSP--PRRPQHNSSGASPRRVR---HDSPDPSPPRR 230
P R D+SP +A +P P P P+ N+ +P+R R S D R
Sbjct: 1473 PSRG--RSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVAR 1530
Query: 231 ARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPR--TKSG 288
G S + + P S + SD+ +A+ +P + + S P +KS
Sbjct: 1531 TPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR 1590
Query: 289 KAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDC 348
+P R+ S +SP K+ + S +P PR +S G + +G
Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSK--GRGPS 1648
Query: 349 QKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSP 408
+ + S SSP H PP+ R + S S P
Sbjct: 1649 PEGSSSTESSPEH------------------------------PPKSRTARRGSRSSPEP 1678
Query: 409 PRRSQPPGKK 418
+S+ P ++
Sbjct: 1679 KTKSRTPPRR 1688
Score = 48.5 bits (114), Expect = 2e-05
Identities = 64/246 (26%), Positives = 91/246 (36%), Gaps = 34/246 (13%)
Query: 203 PRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSD-- 260
PR P S ++ D +P RR+R GSS + + S SR +L S
Sbjct: 1411 PRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSP-----GLRDGSGTPSRHSLSGSSPG 1465
Query: 261 ------TQQLRRARHD-SPDLAPNVTYSLPRTKSGKAP-----------ERASSKTSPHW 302
T R+ D SP+ PR++S +P ER+ S++S
Sbjct: 1466 MKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQ 1525
Query: 303 KESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHK 362
K + L S + D+ P Q +S + DS D + T + L
Sbjct: 1526 KTVARTPLGQRSRSGSSQELDVKPSASPQERS------ESDSSPDSKAKTRTPLRQRSRS 1579
Query: 363 QSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHM 422
S DS S LSP R R SS PR R +S SD SP ++ P
Sbjct: 1580 GSSPEVDSKSRLSP--RRSRSGSSPEVKDKPRAAPRAQSG-SDSSPEPKAPAPRALPRRS 1636
Query: 423 YSGAKT 428
SG+ +
Sbjct: 1637 RSGSSS 1642
Score = 48.1 bits (113), Expect = 2e-05
Identities = 54/165 (32%), Positives = 66/165 (40%), Gaps = 10/165 (6%)
Query: 115 SNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDT 174
+ R R TP + RR R T + R+ R T + RR+R T SP+ R S T
Sbjct: 1954 TRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRT---SPVTRRRSRSRT 2010
Query: 175 SPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHG 234
SP R R S T P R R S P PR+ S SP +R S + PR AR
Sbjct: 2011 SPVTR-RRSRSRTPPAIRRRSRSRTPLLPRK---RSRSRSPLAIRRRSRSRT-PRTARGK 2065
Query: 235 SSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDS--PDLAPN 277
S SP + S S S T R S P +A N
Sbjct: 2066 RSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALN 2110
Score = 41.6 bits (96), Expect = 0.002
Identities = 44/168 (26%), Positives = 59/168 (35%), Gaps = 25/168 (14%)
Query: 124 PDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHD 183
P + R R P P+ RK R + S + + S + S +S
Sbjct: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645
Query: 184 SSDTSPPRRARHDSPDPSPPRRP------------------QHNSSGASPRRVRHDSPDP 225
SS SP + P P+ P++P S SP R SP P
Sbjct: 2646 SSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQP 2705
Query: 226 SPPRRARHGSSDISSPR--RVHNNSPDTSRRTLGSSDTQQLRRARHDS 271
S PR + SS+ S R R + SP RR +T R RH S
Sbjct: 2706 S-PRDQQSSSSERGSRRGQRGDSRSPSHKRR----RETPSPRPMRHRS 2748
Score = 39.3 bits (90), Expect = 0.011
Identities = 40/177 (22%), Positives = 65/177 (36%), Gaps = 29/177 (16%)
Query: 138 PSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDS 197
P R +P P+P+ A + P P +P +R R SS +S + S
Sbjct: 2572 PEVALKRVPSPTPAPKEAVREGRPPEP----------TPAKRKRRSSSSSSSSSSSSSSS 2621
Query: 198 PDPSPPRRPQHNSSGASPRRVRHDSPDPSP-------------PRRARHGSSDISSPRRV 244
S +SS +S S PSP P++ G SPR+
Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP 2681
Query: 245 HNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPH 301
++ D+ R+L S ++ R SP +P S + + +R S++ H
Sbjct: 2682 IDSLRDS--RSLSYSPVER----RRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSH 2732
Score = 38.1 bits (87), Expect = 0.024
Identities = 74/351 (21%), Positives = 115/351 (32%), Gaps = 41/351 (11%)
Query: 124 PDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDT---PDPSPLRGARHDSDTSPPRRI 180
P S+ RV T P + R TP +P ++R + P PS G PP +
Sbjct: 2386 PLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD 2445
Query: 181 RHDSSDTSP-PRRARHDSPDPSPPRRPQHNSSGASPRRVR----HDS----PDPSPPRR- 230
+ S S ++R +P Q SSGA H+ P P P
Sbjct: 2446 QPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSD 2505
Query: 231 --ARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSG 288
S+ P + P RR+ SS + + S + + + S G
Sbjct: 2506 VGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEG 2565
Query: 289 KA----PERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDS 344
+ PE A + S PK + E P P K++ +S S
Sbjct: 2566 SSLPVQPEVALKRVP--------SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSS 2617
Query: 345 KGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDS 404
++ S SS S S S SP +P ++ SP +
Sbjct: 2618 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKK---------- 2667
Query: 405 DLSPP--RRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFE 453
PP RRS+ P K + + +R + +DQ++ + E
Sbjct: 2668 --PPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSE 2716
Score = 37.0 bits (84), Expect = 0.054
Identities = 81/361 (22%), Positives = 136/361 (37%), Gaps = 57/361 (15%)
Query: 124 PDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHD 183
P++ PR+ G+ P P+ P PS L G++ P + +
Sbjct: 981 PETPPRQSHSGSISPYPKVKAQTPPGPS-------------LSGSK---SPCPQEKSKDS 1024
Query: 184 SSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSP-- 241
+ P + S P P + G S +++ S SP R SD SSP
Sbjct: 1025 LVQSCPGSLSLCAGVKSSTP--PGESYFGVSSLQLKGQS-QTSPDHR-----SDTSSPEV 1076
Query: 242 RRVHNNSPDTSRRTLGSSDTQQLRRARHDSP--DLAPNVTYSLPRTKSGKAPERASSKTS 299
R+ H+ SP + S + + R+R SP +LA ++S +R S
Sbjct: 1077 RQSHSESPSLQSK---SQTSPKGGRSRSSSPVTELA---------SRSPIRQDRGEFSAS 1124
Query: 300 PHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSP 359
P K SG S P+ S+++ D P + + +SK D ++
Sbjct: 1125 PMLK-SGMS----PEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATA- 1178
Query: 360 RHKQSPGHQDSDSDLSPPRNRPRHR--SSDSDLSPPRRRQRTKSS----DSDLSPPRRSQ 413
SP Q P ++RP D+ +PPR R SS + + + P SQ
Sbjct: 1179 ----SPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQ 1234
Query: 414 PPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNL 473
S G +L+ + E +E+ + E+ E E + A ++ D+S + +L
Sbjct: 1235 DEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSP-EVEERPAVSLTLDQSQSQASL 1293
Query: 474 K 474
+
Sbjct: 1294 E 1294
Score = 34.7 bits (78), Expect = 0.27
Identities = 31/99 (31%), Positives = 38/99 (38%), Gaps = 16/99 (16%)
Query: 124 PDSSPRRVRHGTPDP------SPRKDRHDTPDP-----SPRRARHDTPDPSPLRGARHDS 172
P + P+ P P SPRK D SP R +P PSP S
Sbjct: 2656 PQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSS 2715
Query: 173 DTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSS 211
+ R R DS SP + R ++P P P R H SS
Sbjct: 2716 ERGSRRGQRGDSR--SPSHKRRRETPSPRPMR---HRSS 2749
Score = 33.1 bits (74), Expect = 0.78
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 5/58 (8%)
Query: 120 RHDTPDSSPRRVRHGTPDPSPRK-DRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSP 176
R +P SPR + + + R+ R D+ PS +R R +TP P P+ RH S SP
Sbjct: 2699 RRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKR-RRETPSPRPM---RHRSSRSP 2752
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 75.9 bits (185), Expect = 1e-13
Identities = 93/319 (29%), Positives = 121/319 (37%), Gaps = 43/319 (13%)
Query: 137 DPSPRKDRHDTPDPSPRRARHDTPDPSPLR-GARHDSDTSPPRRIRHDSSDTSPPRR--- 192
+PSP K+ + R R + S R +R S T P RR R S SP RR
Sbjct: 258 EPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSP 317
Query: 193 ARHDSP-DPSPPRR----PQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRR--VH 245
R SP +PPRR P+H S + RR R S S + S S P++
Sbjct: 318 RRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKR 377
Query: 246 NNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLP------RTKSGK---APERASS 296
+SP R L S + RR R P P T P RT+ + +P R S
Sbjct: 378 TSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSG 437
Query: 297 KTSPH-WKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSD 355
K + H E S PK K E K A + +++ + + Q ++DS
Sbjct: 438 KVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSG 497
Query: 356 LSSPRHKQSP--------------GHQDSDSDLSPPRNR-----PRHRSSDSDLSPPRRR 396
SS + P H S S PR R PR R S PP RR
Sbjct: 498 SSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRR 557
Query: 397 QRTKSSDSDLSPPRRSQPP 415
+R S S PPRR + P
Sbjct: 558 RR---SPSPAPPPRRRRTP 573
Score = 73.6 bits (179), Expect = 5e-13
Identities = 99/395 (25%), Positives = 150/395 (37%), Gaps = 79/395 (20%)
Query: 85 DERPEEVKQMEAFRSSAKWKLLGGHNEDLPSN----RHFRHDTPDSSPRRVRHGTPDPSP 140
+ + E+ K+ RS ++ K PS+ R R + SPRR PSP
Sbjct: 264 NSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSP 323
Query: 141 RK---DRHDTPDPSPRRARHDTPDPSPLRGARHDS------------------------- 172
R+ R P P RR+R SP+R R S
Sbjct: 324 RRRTPPRRMPPPPRHRRSR------SPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKR 377
Query: 173 DTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRA- 231
+SPPR+ R S SPPRR SP +PP + +H+ + R R SP R +
Sbjct: 378 TSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSG 437
Query: 232 ----------RHGSSDISSPRRVH-NNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTY 280
R S PR+V + S + + ++D+ Q RR Y
Sbjct: 438 KVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRR------------QY 485
Query: 281 SLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISP-PRKKQAK-SHFGD 338
+S +SS K S + + ++ SP PRK+Q + S G
Sbjct: 486 RRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGR 545
Query: 339 KKQLDSKGDC-QKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRS-SDSDLSPPRRR 396
+++ S ++ + S PR +++P SPP PR RS S SPP +R
Sbjct: 546 RRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPP---PRRRSPSPRRYSPPIQR 602
Query: 397 QRTKS------SDSDLSPPRR----SQPPGKKAAH 421
+ + S + S PP+R S PP ++ +H
Sbjct: 603 RYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSH 637
Score = 70.9 bits (172), Expect = 3e-12
Identities = 86/354 (24%), Positives = 124/354 (35%), Gaps = 65/354 (18%)
Query: 114 PSNRHFRHDTPDSSPRRVRHG-TPDPSPRK----------------------DRHDTPDP 150
P R R P + P + RH TP S R ++ ++P P
Sbjct: 394 PPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSP 453
Query: 151 SPRRARHDTPDPSPLRGARHDSDTSPPRRIRH---------------DSSDTSPPR---- 191
+P+ + + + +G + + S +R ++ S D P R
Sbjct: 454 APKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVK 513
Query: 192 -----RARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHN 246
R R SP S P+ SPR R SP P PP R R S PRR
Sbjct: 514 NGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSP-PPTRRRRSPSPAPPPRRRRT 572
Query: 247 NSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLP---RTKSGKAPERASSKTSPHWK 303
+P RRT ++ R SP + + S P RT S P + + SP K
Sbjct: 573 PTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPK 632
Query: 304 ESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQ 363
SH PK SP K+++ S ++ S + S + RH
Sbjct: 633 RR-VSHSPPPKQRS-------SPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 684
Query: 364 SPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGK 417
SP + + SPP P R + S P+RRQ S + R+ P K
Sbjct: 685 SPRPRAPQTSSSPP---PVRRGASSS---PQRRQSPSPSTRPIRRVSRTPEPKK 732
Score = 69.3 bits (168), Expect = 1e-11
Identities = 75/265 (28%), Positives = 105/265 (39%), Gaps = 30/265 (11%)
Query: 120 RHDTPDSSPRR------------VRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRG 167
R TP PRR R +P P P++ P P RRA +P P P R
Sbjct: 578 RRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRA---SPSPPPKRR 634
Query: 168 ARHD---SDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPD 224
H S P R S +S R+ S R PQ N + R R
Sbjct: 635 VSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTS 694
Query: 225 PSPPRRARHGSSDISSPRRVHNNSPDTS--RRTLGSSDTQQLRRARHDSPDLAPNVTYSL 282
SPP R G+S SSP+R + SP T RR + + +++++A SP V+ S
Sbjct: 695 SSPP-PVRRGAS--SSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSS- 750
Query: 283 PRTKSGKAPERASSK----TSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGD 338
R+ SG +PE A+ K SP +S +++ S K P SP + + G
Sbjct: 751 -RSVSG-SPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGG 808
Query: 339 KKQLDSKGDCQKATDSDLSSPRHKQ 363
KK+ K K +HK+
Sbjct: 809 KKKKKKKDKKHKKDKKHKKHKKHKK 833
Score = 64.7 bits (156), Expect = 2e-10
Identities = 112/526 (21%), Positives = 192/526 (36%), Gaps = 104/526 (19%)
Query: 79 VVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDP 138
+ + F++ + EE+KQ R + KL +D ++ + + S +R R + P
Sbjct: 119 IPSAFLELKKEEIKQ----RQIEQEKLASMKKQDEDKDKRDKEEKESSREKRER--SRSP 172
Query: 139 SPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSP 198
RK R PSPRR +SP RR R S SP R + SP
Sbjct: 173 RRRKSR----SPSPRRR------------------SSPVRRERKRSHSRSPRHRTKSRSP 210
Query: 199 DPSPPRRP-----------------QHNSSGASPRRVRHDSP-----DPSPPRRARHGSS 236
P+P ++ Q +S + +V P +PSP + ++
Sbjct: 211 SPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKE 270
Query: 237 DISSPRRVHNNSPDTSR-RTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERAS 295
+ R + S SR R+ S T+ RR R S +P P + +P R
Sbjct: 271 KEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPR---RRPSPRRRPSPRR-- 325
Query: 296 SKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSD 355
+T P PPR ++++S ++ + + S
Sbjct: 326 -RTPPRRMP--------------------PPPRHRRSRSPVRRRR----RSSASLSGSSS 360
Query: 356 LSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQR-----TKSSDSDLSP-P 409
SS +SP + SPPR + R SPPRRR R T + SP P
Sbjct: 361 SSSSSRSRSPPKKPPKRTSSPPR---KTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTP 417
Query: 410 RRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGR 469
++S K + G +G V E++E + + E +E DK G+
Sbjct: 418 QQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPR--KVELSESE---EDKGGK 472
Query: 470 KRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDE 529
+ ++QRR+ + +++ + R ++ +V++ ++ R+
Sbjct: 473 M--AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRR---RHSPSR 527
Query: 530 DLDRMLREQEREGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNR 575
R++++E P + + + R R PAPPP R
Sbjct: 528 SASPSPRKRQKETSPRG----RRRRSPSPPPTRRRRSPSPAPPPRR 569
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 73.9 bits (180), Expect = 4e-13
Identities = 113/556 (20%), Positives = 208/556 (37%), Gaps = 59/556 (10%)
Query: 88 PEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRH-----DTP-----DSSPRRVRHGTPD 137
P+ + RS + K G H+ + S H R DT + R R D
Sbjct: 382 PQRKQSPPRHRSPMREK--GRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQD 439
Query: 138 PSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDS 197
S +D D +P R R D D R R D R +R S DT R
Sbjct: 440 QSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESR-----D 494
Query: 198 PDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDI---SSPRRVHNNSPDTSRR 254
P S R H+ R H D P +G + + SS + N S + SR
Sbjct: 495 PRDSRSTRDAHDYRDREGRDT-HRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRS 553
Query: 255 TLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPK 314
+ + ++ R+R P+L ++ + + S ++ ++ +S + S+P+
Sbjct: 554 EIRN---DRMGRSRGRVPELPEK------GSRGSRGSQIDSHSSNSNYHDSWETRSSYPE 604
Query: 315 NSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQ------ 368
+Y + R + G++ + D++ Q+ + R+ + +
Sbjct: 605 RDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERR 664
Query: 369 -----DSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMY 423
D + + R+R R R + + R R R + + +L R + ++
Sbjct: 665 VDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERD 724
Query: 424 SGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRK 483
D RE++ +E+D+E E E + E + R+R + ER E+ R+
Sbjct: 725 RERDRD---RDHDRERERERERDREKER-EREREERERERERERERERERERER-ERARE 779
Query: 484 AEKDSERDELYAQWGKGLAQSRQQQQNVEDAMK-----EMQKPLARYIDD-----EDLDR 533
+K+ ER + KG R++++ + + + +K RY ++ +
Sbjct: 780 RDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPK 839
Query: 534 MLREQEREGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGF 593
RE + D + KN+ ++ VRP+ S P + G RW DR
Sbjct: 840 RRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQG-RWKEEDRKP-- 896
Query: 594 EQKRFARLASKKAVEE 609
E+K +R ++ ++E
Sbjct: 897 ERKESSRRYEEQELKE 912
Score = 45.8 bits (107), Expect = 1e-04
Identities = 97/448 (21%), Positives = 156/448 (34%), Gaps = 66/448 (14%)
Query: 130 RVRHGTPDPSPR-KDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTS 188
R HG PSPR K SP R D + ++ R D DT P +R +SS S
Sbjct: 58 RFVHG---PSPRGKGYSSNYRRSPERPTGDLRER--MKNKRQDVDTEPQKRNTEESS--S 110
Query: 189 PPR----RARHDSPDP---SPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSP 241
P R R RH + + R P+ R DS + H S
Sbjct: 111 PVRKESSRGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKR 170
Query: 242 RRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRT-KSGKAPERASS--KT 298
+++ + + +++ + SP++ + P KS K+P+R SS +
Sbjct: 171 QKIQRELMKLEQENM--EKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSS 228
Query: 299 SPHWKESGASHLSFP-----KNSKYEYD-------PDISPPRK------KQAKSHFGDKK 340
S K+ S +S P +NSK P PP K+ K + K
Sbjct: 229 SASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKD 288
Query: 341 QLDSKGDCQKATDSDLSSPRHKQ----------------SPGHQDSDSDL---------S 375
+++ K K D R K+ S H S S S
Sbjct: 289 RIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPS 348
Query: 376 PPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDI 435
P R R S L+PP RR + LS P+R Q P + + M + T
Sbjct: 349 PRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQ 408
Query: 436 QREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSE--RDEL 493
+++ + +D + E + R+ + +R + + +D+ RD
Sbjct: 409 SHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRR 468
Query: 494 YAQWGKGLAQSRQQQQNVEDAMKEMQKP 521
+ + + SR+ + D KE + P
Sbjct: 469 ELRDSRDMRDSREMRDYSRDT-KESRDP 495
Score = 39.7 bits (91), Expect = 0.008
Identities = 48/243 (19%), Positives = 86/243 (35%), Gaps = 33/243 (13%)
Query: 384 RSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELK 443
RS + R R + K D D P +R+ S DI+ ++
Sbjct: 76 RSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTP 135
Query: 444 EQDQETMAFEAE----------FQYAETVFRDKSGRKRNLKLERLEQRR--KAEKDSERD 491
E ++E + +E + Y + + +K +L +LEQ K E+ +
Sbjct: 136 ESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKK 195
Query: 492 ELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKK 551
E+ + + + + K P + +D R+ P+ + ++
Sbjct: 196 EVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKD-----RKTSAVSSPLLD--QQ 248
Query: 552 NKAKENKNKKVRPRYSGPAPP-PNRFNIWPGYR-------------WDGVDRSNGFEQKR 597
+K N++KK PR P PP P + Y+ DG DR FE++R
Sbjct: 249 RNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQR 308
Query: 598 FAR 600
R
Sbjct: 309 EKR 311
Score = 34.7 bits (78), Expect = 0.27
Identities = 70/319 (21%), Positives = 114/319 (35%), Gaps = 38/319 (11%)
Query: 186 DTSPPRRARHDSPDPSPPRRPQHNSS----GASPRRVRHDSPDPSPPRRARHGS--SDIS 239
DT+ + D PD + +H ++ G++P + P P P A + + ++
Sbjct: 1061 DTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLA 1120
Query: 240 SPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTS 299
+ S TS T+ +S T P N T++ + R +
Sbjct: 1121 ATTAAAATSFSTSAITISTSAT----------PTNTTNNTFANEDSHRKCHRTRVEKVET 1170
Query: 300 PHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSP 359
PH A H P + K S + +SH + + S ++ D D S
Sbjct: 1171 PHVTIEDAQHRK-PMDQKRSS----SLGSNRSNRSHTSGRLRSPSNDSAHRSGD-DQSGR 1224
Query: 360 RHKQSPGHQDSDSDLSPPRNRPRHRSSDS-DLSPPRRRQRTKSSDSDLSPPRRSQPPGKK 418
+ G +D + S R D P R + DS RRS P +
Sbjct: 1225 KRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDR 1284
Query: 419 AAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFR--DKSGRK---RNL 473
H SG+ + L+E+D+ E E + +T R D+ K RN
Sbjct: 1285 QVHSRSGSFD---------SRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNR 1335
Query: 474 KLERLEQR-RKAEKDSERD 491
+RL +R R+ E+D RD
Sbjct: 1336 DRDRLRERERERERDKRRD 1354
Score = 33.1 bits (74), Expect = 0.78
Identities = 68/303 (22%), Positives = 102/303 (33%), Gaps = 55/303 (18%)
Query: 123 TPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRH 182
TP S+P + P P P T P+ A S A S ++ P +
Sbjct: 1089 TPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTN 1148
Query: 183 DSSDTSPPRRARH---------------DSPDPSPPRRPQHNSSGASPRRVRHDSPD-PS 226
++ R H D+ P + + +S G++ H S S
Sbjct: 1149 NTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRS 1208
Query: 227 PPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTK 286
P + H S D S R+ +S R S + R++R D + K
Sbjct: 1209 PSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRID-------------QLK 1255
Query: 287 SGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKG 346
G+ P R++S ++ SH S SP +Q S G DS+
Sbjct: 1256 RGE-PSRSTSSD----RQDSRSHSSRRS----------SPESDRQVHSRSGS---FDSRD 1297
Query: 347 DCQKAT----DSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSS 402
Q+ D + R D D+D PRNR R R + + R R+R K
Sbjct: 1298 RLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERE----RERERDKRR 1353
Query: 403 DSD 405
D D
Sbjct: 1354 DLD 1356
Score = 30.8 bits (68), Expect = 3.9
Identities = 71/348 (20%), Positives = 118/348 (33%), Gaps = 37/348 (10%)
Query: 29 ESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTAISTTKLEKEEEEDDGDLPVVAEFVDERP 88
E R+R ++R K R D + + E+E E ++ + E ER
Sbjct: 710 ERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERE 769
Query: 89 EEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDS--SPRRVRHGTPDPSPRKDRHD 146
E ++ E R K + ED R R + + R R G + +K +
Sbjct: 770 RE-RERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRN 828
Query: 147 TPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRP 206
PSPR+ SP R H D+ D+ ++ + +H S RP
Sbjct: 829 EGSPSPRQ--------SPKRRREHSPDS--------DAYNSGDDKNEKHRLL--SQVVRP 870
Query: 207 QHNSSGASPRRVRHD-----SPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDT 261
Q + S SP + D + P R + +S D R ++
Sbjct: 871 QESRS-LSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILES 929
Query: 262 QQLRR----ARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSK 317
++R H S D + K K ++ K + G + S+
Sbjct: 930 SRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKED--DVGIERGNIETTSE 987
Query: 318 YEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSP 365
D + P+K Q K +KK+ SKGD + + + K+ P
Sbjct: 988 ---DGQVFSPKKGQKKKSI-EKKRKKSKGDSDISDEEAAQQSKKKRGP 1031
>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo
sapiens]
Length = 2365
Score = 68.2 bits (165), Expect = 2e-11
Identities = 83/321 (25%), Positives = 124/321 (38%), Gaps = 31/321 (9%)
Query: 112 DLPSNRHFRHDTPD-SSPRRVRHGTPDPS------PRKDRHDTPDPSPRR------ARHD 158
D P + D P SSP R P S PR R +P+ + R A+ D
Sbjct: 426 DNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRD 485
Query: 159 TPDPS-PLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRR 217
P S P R R + TS +R +S TS P RA D+P S +R N +SP R
Sbjct: 486 NPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRD--NPRASSPNR 543
Query: 218 VRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSP--DLA 275
D+P S +R +S SSP R ++P TS + RA D+P A
Sbjct: 544 AARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCA 603
Query: 276 PNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSH 335
RT S R + +TS +++ S P + + P S R+ ++
Sbjct: 604 QRDNPRASRTSSPNRATRDNPRTSCAQRDN--PRASSPNRTTQQDSPRTSCARRDDPRAS 661
Query: 336 FGDK--KQLDSKGDCQKATDSDLSSPRH-------KQSPGHQDSDSDLSPPRNRPRH--R 384
++ +Q + + C + SSP + S +D SP R + R
Sbjct: 662 SPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPR 721
Query: 385 SSDSDLSPPRRRQRTKSSDSD 405
+S + PR R ++ D
Sbjct: 722 TSCARRDNPRASSRNRTIQRD 742
Score = 57.0 bits (136), Expect = 5e-08
Identities = 75/320 (23%), Positives = 112/320 (35%), Gaps = 33/320 (10%)
Query: 120 RHDTPDSSPRRVRHGTPDPSPRKD--RHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPP 177
R D SSP R T +PR R D P S R +P R + S P
Sbjct: 703 RDDPRASSPNRT---TQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSP 759
Query: 178 RRI-----------RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASP-RRVRHDSPDP 225
R R D+ TS P RA D+P S +R N +SP R + D+P
Sbjct: 760 NRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQR--DNLRASSPIRATQQDNPRT 817
Query: 226 SPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRT 285
+ SS + D R T D Q + D+P + + +
Sbjct: 818 CIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKEN 877
Query: 286 KSGKAPERASS-----KTSPHWKESGASHLSFPKNSKYEYDP-DISPPRKKQAKSHFGDK 339
+P R++ +SPH SFP P SP R KQ++ +
Sbjct: 878 LRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASI 937
Query: 340 KQLDSKGDCQKATD----SDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRR 395
++GD + + + P+ P + S + + P H+S+ SP
Sbjct: 938 ALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSP--- 994
Query: 396 RQRTKSSDSDLSPPRRSQPP 415
+ + L+ P SQPP
Sbjct: 995 -VYPAAYGAPLTSPEPSQPP 1013
Score = 47.8 bits (112), Expect = 3e-05
Identities = 117/543 (21%), Positives = 181/543 (33%), Gaps = 90/543 (16%)
Query: 88 PEEVKQMEA-FRSSAKWKLLGGHNEDLPSNRHFRHDTPDSS--------PRRVRHGTPDP 138
P KQ E + S A G + +R +HD P SS P R + +P
Sbjct: 924 PSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNP 983
Query: 139 SPRK-DRHDTPD-PSPRRARHDTPDPSPLRGA----RHDSD--TSPPRRIRHDSSDTSP- 189
+ R +P P+ A +P+PS A D+ +SPPR ++HD P
Sbjct: 984 GHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPE 1043
Query: 190 PRRARHDSPDPSPPRRPQ-----HNSSGASPRRVRHDSPDPSP----PRRARHGSSDISS 240
PR + P PP P H + + RH DP P A H S
Sbjct: 1044 PRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEH---QCQS 1100
Query: 241 PRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTY-SLPRTKS-GKAPERASSKT 298
P+ H + +G D + +P+ P++ + LPR + P S
Sbjct: 1101 PQ--HEPLQLPAPVCIGYRDAPRASSPPRQAPE--PSLLFQDLPRASTESLVPSMDSLHE 1156
Query: 299 SPHWKESGA-SHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDS--- 354
PH H P S SPPR+ S F S +TDS
Sbjct: 1157 CPHIPTPVCIGHRDAPSFS--------SPPRQAPEPSLFFQDPPGTSMESLAPSTDSLHG 1208
Query: 355 -----------DLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSD 403
+PR P H SD P P +PP + +
Sbjct: 1209 SPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLERE 1268
Query: 404 -----SDLSPPRR--SQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEF 456
+DL PPRR + PG +A G +++R + + + + AF+A+
Sbjct: 1269 EYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQ- 1327
Query: 457 QYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMK 516
GR + + + R+ + ++ K +R+ Q
Sbjct: 1328 ---------DEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWS 1378
Query: 517 EMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRF 576
++P + DR L +G P+ + E + + RP SG A P
Sbjct: 1379 PEKRP--------EGDRQL-----QGSPLPPRTSA-RTPERELRTQRPLESGQAGPRQPL 1424
Query: 577 NIW 579
+W
Sbjct: 1425 GVW 1427
Score = 40.0 bits (92), Expect = 0.006
Identities = 97/439 (22%), Positives = 153/439 (34%), Gaps = 47/439 (10%)
Query: 6 PLSKAEYLKRYLSGADAGVDRGSESGRKRRKKR----PKPGGAGGKGMRIVD-DDVSWTA 60
P + + L SG + VD G G KR P+ G R + + V +
Sbjct: 57 PPAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLE 116
Query: 61 ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120
TT L ED G P + P++ SS W + E+ PS
Sbjct: 117 GLTTSLCGSCNEDPGSDPTSSPD-SATPDDTSNS----SSVDWDTVERQEEEAPS----W 167
Query: 121 HDTPDSSPRRVRHGT-PDPSPRKDRHDTPDP----SPRRARHDTPDPSPLRGA-----RH 170
+ PRR R G D S R T P + + + DT G R
Sbjct: 168 DELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRG 227
Query: 171 DSDTSPPRR--IRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRV-RHDSPDPSP 227
+S S R +S +P R + SP +R + AS R + R SP
Sbjct: 228 ESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRD--TAQAASTREIPRASSPHRIT 285
Query: 228 PRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKS 287
R SS R + +TSR + DT + + D+P A + ++ PR S
Sbjct: 286 QRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPR-ASSTQWNTPRASS 344
Query: 288 GKAPERASSKTSPHWKESGASH--LSFPKNSKYEYDPDI-----------SPPRKKQAKS 334
P R++ +P + + SFP + +P SP R Q ++
Sbjct: 345 ---PSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQREN 401
Query: 335 HFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPR-NRPRHRSSDSDLSPP 393
Q D+ + ++ + + + S +D+ SP R R +S + P
Sbjct: 402 SRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNP 461
Query: 394 RRRQRTKSSDSDLSPPRRS 412
R + + + + PR S
Sbjct: 462 RASRTSSPNRATRDNPRTS 480
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 67.8 bits (164), Expect = 3e-11
Identities = 90/345 (26%), Positives = 127/345 (36%), Gaps = 53/345 (15%)
Query: 119 FRHDTPDSSPRRVRHGTP-----DPSPRKDR------HDTPDP----SPRRARHDTPDPS 163
+R TP R RH PS R R H +P SP R H +P
Sbjct: 1545 YRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSER 1604
Query: 164 PLRGARHDSDTSPPRRIRHDSSDT---SP-------PRRARHDSPDPSPPRRPQHNSSGA 213
R + SPP R H S+ SP P + RH SP R P S +
Sbjct: 1605 SWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRS 1664
Query: 214 SPRRVRHDSPDPSPPRRARHGSSDIS--SPRRVHNNSPDTSRRTLGSSDTQQLRRARHDS 271
S R RH SP +R+ G S+ S SP + SP + R G S+ RH S
Sbjct: 1665 SSER-RHRSPS----QRSHRGPSERSHCSPSERRHRSP-SQRSHRGPSE------RRHHS 1712
Query: 272 PDLAPNVTYSLPRTKSGKAPERAS----SKTSPHWKESGASHLSFPKNSKYEYDPDISPP 327
P ++ P +S ++P S S+ S H H ++ + P
Sbjct: 1713 PS---KRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSP 1769
Query: 328 RKKQAKSHFGDKKQLDSKGDCQKATDSDLSSP--RHKQSPGHQDSDSDLS----PPRNRP 381
+++ +S + S+ ++ SP R + SP + S L P R
Sbjct: 1770 SERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERR 1829
Query: 382 RHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQ-PPGKKAAHMYSG 425
HRS + R + S S LSP RS+ P ++ H SG
Sbjct: 1830 SHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSG 1874
Score = 61.6 bits (148), Expect = 2e-09
Identities = 85/321 (26%), Positives = 116/321 (36%), Gaps = 40/321 (12%)
Query: 115 SNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDP----SPRRARHDTPDPSPLRGARH 170
S+ RH +P R SP + RH +P P RH +P R
Sbjct: 1664 SSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPAR 1723
Query: 171 DSDTSPPRRIRHDSSDTS--PPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPP 228
S SP R H S+ S P RH SP P S SP RH SP
Sbjct: 1724 RSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSH-CSPSERRHRSPS---- 1778
Query: 229 RRARHGSSDIS--SPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTK 286
R H S+ S SP ++SP RR L R+RH L S +
Sbjct: 1779 ERRHHSPSEKSHHSPSERSHHSPSERRR------HSPLERSRH---SLLERSHRSPSERR 1829
Query: 287 SGKAPERASSKTSPH-WKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSK 345
S ++ ER+ + S S SHLS + S+ SP + + H K S
Sbjct: 1830 SHRSFERSHRRISERSHSPSEKSHLSPLERSR------CSP---SERRGHSSSGKTCHSP 1880
Query: 346 GDCQKATDSDLSSPRHKQSPGHQDS--DSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSD 403
+ + S + R + H+ S + SP RP S + SP R +R
Sbjct: 1881 SERSHRSPSGMRQGRTSER-SHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRR----- 1934
Query: 404 SDLSPPRRSQPPGKKAAHMYS 424
S L + PG++ +H S
Sbjct: 1935 SPLKEGLKYSFPGERPSHSLS 1955
Score = 54.7 bits (130), Expect = 2e-07
Identities = 59/240 (24%), Positives = 79/240 (32%), Gaps = 28/240 (11%)
Query: 88 PEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDT 147
P E + + S + H + H + SP RH +P +
Sbjct: 1705 PSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSER 1764
Query: 148 PDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDT---SPPRRARH---DSPDPS 201
SP RH +P S SP R H S+ SP R+RH + S
Sbjct: 1765 SHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRS 1824
Query: 202 PPRRPQHNSSGASPRRVRHDSPDP--------------SPPRRARHGSS--DISSPRRVH 245
P R H S S RR+ S P SP R H SS SP
Sbjct: 1825 PSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERS 1884
Query: 246 NNSPDTSR--RTLGSSDTQQLRRARHDSPDLAP----NVTYSLPRTKSGKAPERASSKTS 299
+ SP R RT S R RH ++ P + P +S ++P + K S
Sbjct: 1885 HRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYS 1944
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 65.5 bits (158), Expect = 1e-10
Identities = 91/432 (21%), Positives = 157/432 (36%), Gaps = 34/432 (7%)
Query: 123 TPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRH 182
TP S + R G PR + D PR + P G S+ +
Sbjct: 160 TPTSQQKGSR-GKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAK 218
Query: 183 DSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPR 242
+ T P + + D+P PS R+ + P R + SP R + + S
Sbjct: 219 CQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRP 278
Query: 243 RVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERA-SSKTSPH 301
+ H+ S R GS Q+ +R S N + + RT+ G + S++ H
Sbjct: 279 QSHSQSRSPRRSRSGS---QKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSH 335
Query: 302 WKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRH 361
K + P+ + ++ +P +++ K+ D +G +S S
Sbjct: 336 SKGKSQNQSRTPRRGR-SHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRS---Q 391
Query: 362 KQSPGHQ-DSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPR---------R 411
SP Q D SP + R R RS + R R R+ + D S R R
Sbjct: 392 SGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSR 451
Query: 412 SQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKR 471
S+ P K H S +++ D R + KE+D + + +++ R+
Sbjct: 452 SRSPNKARDH--SRSRSPNKARDRSRSRSPSKERDHSQLGSPS---------KERDHRRS 500
Query: 472 NLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDL 531
+ + R+ ERD + + ++ RQ++Q+ KE + +R +E
Sbjct: 501 RSPSKERQCRQSRSSSKERDH---RRSRSPSKERQRRQS-RSPNKERDRSQSRSPSEERE 556
Query: 532 DRMLREQEREGD 543
R R +E D
Sbjct: 557 HRQSRSPSKERD 568
Score = 62.8 bits (151), Expect = 9e-10
Identities = 82/338 (24%), Positives = 130/338 (38%), Gaps = 39/338 (11%)
Query: 98 RSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARH 157
R S+ + G ++ N+ H SP + R + SP K R + SP +AR
Sbjct: 378 RGSSSPRKESGRSQSGSPNKQRDHSR-SRSPNKARDRSRSRSPYKARDRSRSRSPNKARD 436
Query: 158 DTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGA-SPR 216
+ SP + AR S + P + R D S + P +AR S SP + H+ G+ S
Sbjct: 437 CSRSRSPYK-ARDRSRSRSPNKAR-DHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKE 494
Query: 217 RVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAP 276
R S PS R+ R S SS R H RR+ S +Q R++R +P
Sbjct: 495 RDHRRSRSPSKERQCRQSRS--SSKERDH-------RRSRSPSKERQRRQSR------SP 539
Query: 277 NVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHF 336
N K +R+ S++ +E S + + + SP ++++ +
Sbjct: 540 N-----------KERDRSQSRSPSEEREHRQSRSPSKERDRRRWR---SPSKERERRQSR 585
Query: 337 GDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRR 396
++ D S S PR S N + R+S + S P +
Sbjct: 586 SSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKE-SDPSQS 644
Query: 397 QRTKSSDSDLSPPRRS-----QPPGKKAAHMYSGAKTG 429
+S D SP R S + P K ++H S +G
Sbjct: 645 TVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSG 682
Score = 60.5 bits (145), Expect = 5e-09
Identities = 91/406 (22%), Positives = 150/406 (36%), Gaps = 46/406 (11%)
Query: 108 GHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRG 167
G + S+ + +PRR R +P K+R + S + R SP +
Sbjct: 327 GRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKE 386
Query: 168 ARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSP 227
+ SP + + D S + P +AR S S P + + S SP + R S SP
Sbjct: 387 SGRSQSGSPNK--QRDHSRSRSPNKARDRSRSRS-PYKARDRSRSRSPNKARDCSRSRSP 443
Query: 228 PRRARHGSSDISSPRRVH--NNSPDTSR-RTLGSSDTQQLRRARHDSPDLAPNVTYSLPR 284
+ S + R H + SP+ +R R+ S +++ ++ SP + S
Sbjct: 444 YKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSP 503
Query: 285 TKSGKAPE-RASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLD 343
+K + + R+SSK H + SP +++Q + K+ D
Sbjct: 504 SKERQCRQSRSSSKERDHRRSR-------------------SPSKERQRRQSRSPNKERD 544
Query: 344 SKGDCQKATDSDLSSPRHKQSPG-HQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSS 402
Q + S+ R +SP +D SP + R R +S S R R+ +
Sbjct: 545 RS---QSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNK 601
Query: 403 DSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETV 462
S S PR S K+ AH S ++T + + + KE D TV
Sbjct: 602 QSGYSRPRAS---SKEKAH--SRSRTPSKEGNHSQSRTSSKESDPS----------QSTV 646
Query: 463 FRDKSGRKRNLKLERLEQRRKAEKDSERD-ELYAQWGKGLAQSRQQ 507
R ++ + L Q R K S + G+ L+Q Q
Sbjct: 647 PRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQ 692
Score = 58.9 bits (141), Expect = 1e-08
Identities = 71/281 (25%), Positives = 100/281 (35%), Gaps = 19/281 (6%)
Query: 127 SPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSD 186
SP + R + SP K R + SP +AR + SP + SP + H
Sbjct: 430 SPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLG 489
Query: 187 TSPPRRARHDSPDPSPPRRPQHNSSGA---------SPRRVRHDSPDPSPPRRARHGSSD 237
+ R S PS R+ + + S + SP + R SP + S
Sbjct: 490 SPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSR 549
Query: 238 ISSPRRVHNNSPDTS----RRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPER 293
S R H S S RR S ++ RR S + + P +SG + R
Sbjct: 550 SPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPR 609
Query: 294 ASSKTSPHWKE---SGASHLSFPKNSKYEYDPDISP-PRKKQAKSHFGDKKQLDSKGDCQ 349
ASSK H + S + S + S E DP S PR K L
Sbjct: 610 ASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPS 669
Query: 350 KATDSDLSS-PRHKQSPGHQDSDSDLSPPR-NRPRHRSSDS 388
K + S+ P Q+ DS +D + + P RSS S
Sbjct: 670 KTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSS 710
Score = 53.5 bits (127), Expect = 6e-07
Identities = 71/288 (24%), Positives = 110/288 (38%), Gaps = 27/288 (9%)
Query: 92 KQMEAFRSSAKWKLLGGHNEDLPSNR--HFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPD 149
K + RS + +K P+ H R +P+ + R R + PS +D
Sbjct: 433 KARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSR--SRSPSKERDHSQLGS 490
Query: 150 PSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDP--------S 201
PS R + PS R R +S R R S + +R + SP+ S
Sbjct: 491 PSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRS 550
Query: 202 PPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGS--- 258
P +H S SP + R SP + S SS R H+ S ++++ S
Sbjct: 551 PSEEREHRQS-RSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPR 609
Query: 259 SDTQQLRRARHDSPDLAPNVTYSLPRTKSGKA-PERASSKTSPHWKESGASHLSFPKNSK 317
+ +++ +R +P N +S RT S ++ P +++ SP WK S S +N
Sbjct: 610 ASSKEKAHSRSRTPSKEGN--HSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRT 667
Query: 318 YEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQ-KATDSDLSSPRHKQS 364
SP S F Q S+ D Q AT S + P + S
Sbjct: 668 PSKTSSHSP-------STFPSGGQTLSQDDSQADATTSKATLPGERSS 708
Score = 45.4 bits (106), Expect = 2e-04
Identities = 75/318 (23%), Positives = 107/318 (33%), Gaps = 42/318 (13%)
Query: 126 SSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSS 185
SSP+R + +P T DP P + T +P R + + SS
Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
Query: 186 DTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVH 245
S + +P P R + S +P RV D+ R + +S R H
Sbjct: 62 SKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDT---------RTSKASKASDVRCH 112
Query: 246 NNSPDTSR-RTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKE 304
SR RT G ++ +R SP A T RT G P AS +P ++
Sbjct: 113 QRRGTHSRGRTPGRRGSRSSKR----SPSRAS--TPGRIRT-HGARPGMASRVRTPTSQQ 165
Query: 305 SGASHLSFPKNSKYEYDPDISPPRKKQAKSH-------FGDKKQL---DSKGDCQKATDS 354
G+ S+ + + S PR KS+ G +L S CQ T
Sbjct: 166 KGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPT-- 223
Query: 355 DLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKS-----------SD 403
P ++S S S + S + SP R KS S
Sbjct: 224 --GIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSH 281
Query: 404 SDLSPPRRSQPPGKKAAH 421
S PRRS+ +K H
Sbjct: 282 SQSRSPRRSRSGSQKRTH 299
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 63.5 bits (153), Expect = 5e-10
Identities = 100/468 (21%), Positives = 174/468 (37%), Gaps = 54/468 (11%)
Query: 107 GGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKD-----RH--DTPDPSPRRARHDT 159
G ED + +H DT RH + S R+D H D+ + P
Sbjct: 26 GSDGEDDVNEQHSGSDTGSVE----RHSENETSDREDGLPKGHHVTDSENDEPLNLNASD 81
Query: 160 PDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVR 219
+ L + DSD+ R +SD+ +H S S R S + +
Sbjct: 82 SESEELHRQK-DSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLN 140
Query: 220 HDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVT 279
+ D +H +SD + + + S+T+ + P ++ + +
Sbjct: 141 GHASDSENEDVGKHPASD--------SEIEELQKSPASDSETEDALK-----PQISDSES 187
Query: 280 YSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDK 339
PR ++ + K P +S + L P+ S E + PPR + + S +
Sbjct: 188 EEPPRHQASDSENEEPPK--PRMSDSESEELPKPQVSDSESE---EPPRHQASDS---EN 239
Query: 340 KQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRT 399
++L + +DS+ P P HQ SDS+ P+ R SDS+ P R Q +
Sbjct: 240 EELPK----PRISDSESEDP-----PRHQASDSE---NEELPKPRISDSESEDPPRNQAS 287
Query: 400 KSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELK---EQDQETMAFEAEF 456
S + +L PR S ++ G + D R +Q+ + + D+E + E
Sbjct: 288 DSENEELPKPRVSD---SESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEM 344
Query: 457 QYAETVFRDKSGRKRNLKLERLEQRRKAEK-DSERDELYAQWGKGLAQSRQQQQNVEDAM 515
Q RK+ + E+ K +K DS+ DE + K + + ED
Sbjct: 345 QNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEE 404
Query: 516 KEMQKP--LARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKK 561
K K + DD D D + + + +A+ ++ KE +KK
Sbjct: 405 KASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKK 452
Score = 50.8 bits (120), Expect = 4e-06
Identities = 93/484 (19%), Positives = 167/484 (34%), Gaps = 61/484 (12%)
Query: 70 EEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPR 129
E ED G P ++E + + K ++ +E+ P RH D+ + P
Sbjct: 147 ENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPP--RHQASDSENEEPP 204
Query: 130 RVRHGTPD----PSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSS 185
+ R + P P+ ++ +P +A + P PPR DS
Sbjct: 205 KPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSE 264
Query: 186 DTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVH 245
+ P+ DS PPR +S + R + P++ S+ R H
Sbjct: 265 NEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASR-H 323
Query: 246 NNSP---DTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHW 302
P D S R DT+ + H + +S + S+ H
Sbjct: 324 KQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHS------------SDSEEEEHK 371
Query: 303 KESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHK 362
K+ S + E + + RK S D+++ +K + +D+D
Sbjct: 372 KQKMDS-----DEDEKEGEEEKVAKRKAAVLSDSEDEEKASAK-KSRVVSDAD------- 418
Query: 363 QSPGHQDSDSDLSPPRNRPRHR--SSDSDLSPPRRRQRTKSSDSDL--SPPRRSQPPGKK 418
DSDSD ++ R + +SDS+ + K+ + DL S
Sbjct: 419 ------DSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENL 472
Query: 419 AAHMY--SGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLE 476
A ++ SG + T Q++L+E+ ET EAE ++ + E
Sbjct: 473 IADIFGESGDEEEEEFTGF--NQEDLEEEKGETQVKEAEDSDSDDNIKRGKHMDFLSDFE 530
Query: 477 RLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLR 536
+ QR+K+ R ++R + DA + + + + + DR L
Sbjct: 531 MMLQRKKSMSGKRR------------RNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLN 578
Query: 537 EQER 540
Q++
Sbjct: 579 NQKK 582
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 62.0 bits (149), Expect = 2e-09
Identities = 89/392 (22%), Positives = 128/392 (32%), Gaps = 37/392 (9%)
Query: 25 DRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTAISTTKLEKEEEEDDGDLPVVAEFV 84
D G ++G +R P +GG G W + + G P A
Sbjct: 284 DEGRKTGSQRSSGSRSPSPSGGSG---------WGSPQRNGGSGQRSGAHGGRPGSAHSP 334
Query: 85 DERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPR--RVRHGTPDPSPRK 142
++P +++A ++ PS R P S R R G R+
Sbjct: 335 PDKPSSPSPRVRDKAAAAAPTPPARGKESPSPR----SAPSSQGRGGRAAGGAGRRRRRR 390
Query: 143 DRHDTPDPS---PRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPD 199
R S PRR P P+P RG+ + SSD+ R A P+
Sbjct: 391 RRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRA------RSSSDSGSGRGAPGPGPE 444
Query: 200 PSPPRRPQHNSSGAS--PRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLG 257
P R + A P R R S PSP R G + S R SP R+
Sbjct: 445 PGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSR----SPGPHPRSWS 500
Query: 258 SSDTQQLRRARH-----DSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSF 312
SS + R+R SP +P+ L R K G+ R S + + S+
Sbjct: 501 SSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSY--S 558
Query: 313 PKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDS 372
P + P PR+ + S SD S+ H +SP S
Sbjct: 559 PIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHG 618
Query: 373 DLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDS 404
S + R R+ +P SS+S
Sbjct: 619 SYSSRSHGTRSRTRSPSRTPSPSYHSRSSSES 650
Score = 56.2 bits (134), Expect = 9e-08
Identities = 87/396 (21%), Positives = 140/396 (35%), Gaps = 62/396 (15%)
Query: 58 WTAISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNR 117
W++ S + K++++ G R + +++E+ S L + + +R
Sbjct: 159 WSSSSASPPPKKKKKKKGG--------HRRSRKKRRLESECSCGSSSPLRKKKKSVKKHR 210
Query: 118 HFRHDTPDSSPRRVRHGTP-----DPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDS 172
R D+ RR R + + + K R T P R RH + + H S
Sbjct: 211 RDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYS 270
Query: 173 DTSPPRRI----RHDSSDTSPPRRARHDSPDPS------PPRR----------------- 205
D+ P R+ R + T R + SP PS P+R
Sbjct: 271 DSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGS 330
Query: 206 ---PQHNSSGASPR-RVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDT 261
P S SPR R + + P+PP R + S S+P +S R G +
Sbjct: 331 AHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAP-----SSQGRGGRAAGGAGR 385
Query: 262 QQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYD 321
++ RR R + + R + AP R SS++ + S S + +
Sbjct: 386 RRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDS-----GSGRGAPG 440
Query: 322 PDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRP 381
P P + H G K+ + + + S H + G + S SP P
Sbjct: 441 PG---PEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSP---GP 494
Query: 382 RHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGK 417
RS S SP + R R S++ P RS P K
Sbjct: 495 HPRSWSSSRSPSKSRSR--SAEKRPHSPSRSPSPKK 528
Score = 32.7 bits (73), Expect = 1.0
Identities = 37/149 (24%), Positives = 47/149 (31%), Gaps = 36/149 (24%)
Query: 301 HWKESGASHLSFPKNSKYEYDPDISPPRKKQAKS--HFGDKKQLDSKGDCQKATDSDLSS 358
HW S AS PP+KK+ K H +K+ + +C + S L
Sbjct: 158 HWSSSSAS----------------PPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRK 201
Query: 359 PRHKQSPGHQDSDSDLSPPRNRPRHRSSD------------SDLSPPRRRQRTKSSDSDL 406
+ +D S + R R RSS P RR SS S
Sbjct: 202 KKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSH 261
Query: 407 SPPRRS------QPPGKKAAHMYSGAKTG 429
SP S P H G KTG
Sbjct: 262 SPSLSSHYSDSRSPSRLSPKHRDEGRKTG 290
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 59.3 bits (142), Expect = 1e-08
Identities = 84/363 (23%), Positives = 129/363 (35%), Gaps = 13/363 (3%)
Query: 53 DDDVSWTAISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNED 112
D S ++ S+ + + D D ++ D + + K E+ S + K ++
Sbjct: 589 DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS-ESDSSDSDSK-----SDS 642
Query: 113 LPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDS 172
SN D DSS + D S D D+ S D+ D S + S
Sbjct: 643 SDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS 702
Query: 173 DTSPPRRI-RHDSSDTSPPRRARHDSPDPSPPRRPQHNS--SGASPRRVRHDSPDPSPPR 229
D+S DSSD+S + DS + S ++S S +S DS D S
Sbjct: 703 DSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 762
Query: 230 RARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGK 289
+ S S +++ S + SSD+ + S + + + S + S
Sbjct: 763 NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN--SSDSSDSSDSSDSDS 820
Query: 290 APERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQ 349
+ SS +S S +S S +S D D S S D + D
Sbjct: 821 SNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS 880
Query: 350 KATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPP 409
++DS+ SS S SDSD S N SSDS S S +S+ S
Sbjct: 881 DSSDSNESSNSSDSSDSSNSSDSDSSDSSN--SSDSSDSSNSSDSSESSNSSDNSNSSDS 938
Query: 410 RRS 412
S
Sbjct: 939 SNS 941
Score = 55.5 bits (132), Expect = 1e-07
Identities = 73/292 (25%), Positives = 105/292 (35%), Gaps = 22/292 (7%)
Query: 122 DTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIR 181
D+ DSS + D S D D+ D S D+ D S + + SD++
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN------ 786
Query: 182 HDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSP 241
DSS++S DS D S NSS +S DS D S + S SS
Sbjct: 787 -DSSNSS-------DSSDSS-------NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831
Query: 242 RRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPH 301
+NS D+S + S + R DS + + + S S + S+++S
Sbjct: 832 SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS 891
Query: 302 WKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRH 361
S +S+ S +S D S S + + D ++DS SS
Sbjct: 892 SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951
Query: 362 KQSPGHQDSD-SDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRS 412
S SD S+ S + SSDS S S SD S S
Sbjct: 952 NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003
Score = 53.9 bits (128), Expect = 4e-07
Identities = 68/299 (22%), Positives = 108/299 (36%), Gaps = 17/299 (5%)
Query: 115 SNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARH--DTPDPSPLRGARHDS 172
SN +D+ +SS + D S D D+ D S + + D+ + S + + S
Sbjct: 780 SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839
Query: 173 DTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRAR 232
D+S DSSD S + S +SS +S DS + S +
Sbjct: 840 DSSDSS----DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS 895
Query: 233 HGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPE 292
S+ S +NS D+S + S ++ + + + + N + S + S + +
Sbjct: 896 DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 955
Query: 293 RASSKTSPHWKESGASHLSFPKNSKYEYD----PDISPPRKKQAKSHFGDKKQLDSKGDC 348
++S S + +S S+ S +S D D S S+ D D
Sbjct: 956 SSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015
Query: 349 QKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLS 407
++DS SS S SDS S SSDS S S SD S
Sbjct: 1016 SNSSDSSNSSDSSNSSDSSDSSDSSDSSD-------SSDSSDSSDSSNSSDSSDSSDSS 1067
Score = 51.6 bits (122), Expect = 2e-06
Identities = 72/304 (23%), Positives = 105/304 (34%), Gaps = 17/304 (5%)
Query: 115 SNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGA------ 168
SN D+ DSS + D S D D+ D S D+ D S +
Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS 719
Query: 169 ---RHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDP 225
DSD+S DSSD+S + DS D S +SS +S DS D
Sbjct: 720 NSNSSDSDSSN----SSDSSDSSNSSDS-SDSSD-SSNSSDSSDSSDSSNSSDSSDSSDS 773
Query: 226 SPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRT 285
S + + S S ++ S + SSD+ + + + + S +
Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833
Query: 286 KSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYD-PDISPPRKKQAKSHFGDKKQLDS 344
S + + + S S +S +S+ S NS D D S S +
Sbjct: 834 DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893
Query: 345 KGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRN-RPRHRSSDSDLSPPRRRQRTKSSD 403
D ++DSD S + + SD S N SSDS S S+
Sbjct: 894 SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953
Query: 404 SDLS 407
SD S
Sbjct: 954 SDSS 957
Score = 51.6 bits (122), Expect = 2e-06
Identities = 75/297 (25%), Positives = 100/297 (33%), Gaps = 32/297 (10%)
Query: 110 NEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGAR 169
N SN D+ DSS D S D D+ D S D+ D S +
Sbjct: 1023 NSSDSSNSSDSSDSSDSS---------DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073
Query: 170 HDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPR 229
SD+S DSS++S DS D S NSS +S DS D S
Sbjct: 1074 DSSDSS-------DSSESS-------DSSDSS-------NSSDSSDSSDSSDSSDSSDSS 1112
Query: 230 RARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGK 289
+ S +S ++ S + SSD+ + DS D + + S S
Sbjct: 1113 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES-SDSSDSSDSSDSSDSSDSSDS 1171
Query: 290 APERASSKTSPHWKESGASHLSFPKNSKYEYD-PDISPPRKKQAKSHFGDKKQLDSKGDC 348
+ SS +S S +S S +S D D S S D D
Sbjct: 1172 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1231
Query: 349 QKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSD 405
+++DS SS S SDS S + SDS SDSD
Sbjct: 1232 NESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSD 1288
Score = 50.8 bits (120), Expect = 4e-06
Identities = 78/292 (26%), Positives = 102/292 (34%), Gaps = 30/292 (10%)
Query: 122 DTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIR 181
D+ DSS + D S D D+ D S D+ D S + SD+S
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS--- 1067
Query: 182 HDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSP 241
DSSD+S + S S NSS +S DS D S SSD SS
Sbjct: 1068 -DSSDSSDSSDSSDSSE--SSDSSDSSNSSDSSDSSDSSDSSDSSD-------SSD-SSD 1116
Query: 242 RRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPH 301
+NS D+S SSD+ DS D + + S S + SS +S
Sbjct: 1117 SSDSSNSSDSS----DSSDSS-------DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDS 1165
Query: 302 WKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRH 361
S +S S NS D S S D D ++DS SS
Sbjct: 1166 SDSSDSSDSSDSSNSS-----DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1220
Query: 362 KQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQ 413
S SDS+ S + S S+ S + S SD + SQ
Sbjct: 1221 DSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQ 1272
Score = 50.4 bits (119), Expect = 5e-06
Identities = 71/298 (23%), Positives = 105/298 (35%), Gaps = 23/298 (7%)
Query: 130 RVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDT-----SPPRRIRHDS 184
+V H D +D+ D + + D P+ S D+++ S R +
Sbjct: 435 KVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYN 494
Query: 185 SDTSPPRRARHDSP----DPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISS 240
SD S DS D S +NS +D D S + + SSD S
Sbjct: 495 SDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDS 554
Query: 241 PRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSP 300
+NS D+S + S + + DS D + + + S + + + S S
Sbjct: 555 SDS--SNSSDSSDSS-DSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSS 611
Query: 301 HWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPR 360
+S S S +SK E D S + + S+ D D +++S SS
Sbjct: 612 DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDS 671
Query: 361 HKQSPGHQDSD-------SDLSPPRNRPRHR----SSDSDLSPPRRRQRTKSSDSDLS 407
S SD SD S N SSDSD S + SSDSD S
Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSS 729
Score = 50.4 bits (119), Expect = 5e-06
Identities = 75/291 (25%), Positives = 104/291 (35%), Gaps = 33/291 (11%)
Query: 115 SNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDT 174
SNR ++ DSS + D S D D+ D + D+ D S + DS
Sbjct: 856 SNRSDSSNSSDSS------DSSDSSNSSDSSDSSDSNESSNSSDSSDSS--NSSDSDSSD 907
Query: 175 SPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHG 234
S DSS++S + + S + NSS +S DS D S
Sbjct: 908 SSNSSDSSDSSNSSDSSESSNSSDN--------SNSSDSSNSSDSSDSSDSS-------N 952
Query: 235 SSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERA 294
SSD S+ N+S + + SSD+ DS D + + S S +
Sbjct: 953 SSDSSNSSDSSNSSDSSDSNSSDSSDSSN----SSDSSDSSDSSDSSDSSDSSNSSDSSD 1008
Query: 295 SSKTSPHWKESGASHLSFPKNSKYEYD-PDISPPRKKQAKSHFGDKKQLDSKGDCQKATD 353
SS +S S +S+ S NS D D S S D D ++D
Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1068
Query: 354 SDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDS 404
S SS S + SDS S + S SD S + SSDS
Sbjct: 1069 SSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS-----DSSDSSDS 1114
Score = 49.3 bits (116), Expect = 1e-05
Identities = 78/305 (25%), Positives = 105/305 (34%), Gaps = 17/305 (5%)
Query: 110 NEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGAR 169
N SN D+ DSS + + D S D D+ + S D+ D G+
Sbjct: 799 NSSDSSNSSDSSDSSDSSDSDSSNSS-DSSNSSDSSDSSNSSDSSDSSDSSD-----GSD 852
Query: 170 HDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPR 229
DS DSSD+S + DS D S NSS +S DS
Sbjct: 853 SDSSNRSDSSNSSDSSDSSDSSNSS-DSSDSSDSNESS-NSSDSSDSSNSSDSDSSDSSN 910
Query: 230 RARHGSSDISSPRRVHNNSPDTSRR--TLGSSDTQQLRRARHDSPDL----APNVTYSLP 283
+ S SS +NS D S + SSD+ + + S + N + S
Sbjct: 911 SSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 970
Query: 284 RTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYD-PDISPPRKKQAKSHFGDKKQL 342
S + SS +S S +S S NS D D S S+ D
Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS 1030
Query: 343 DSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSS 402
D ++DS SS S SDS S + S SD S + + SS
Sbjct: 1031 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD--SSESSDSS 1088
Query: 403 DSDLS 407
DS S
Sbjct: 1089 DSSNS 1093
Score = 47.8 bits (112), Expect = 3e-05
Identities = 71/298 (23%), Positives = 105/298 (35%), Gaps = 21/298 (7%)
Query: 115 SNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDT 174
SN ++ DSS + D S D D+ D S R ++ D S + + SD+
Sbjct: 821 SNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDS-DSSNRSDSSNSSDSSDSSDSSNSSDS 879
Query: 175 SPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHG 234
S DSSD++ + S + +SS +S +S D S +
Sbjct: 880 S-------DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932
Query: 235 S-------SDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKS 287
S S SS +NS D+S + S+ + DS D + + S S
Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992
Query: 288 GKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQA-KSHFGDKKQLDSKG 346
+ SS +S S +S S +S D S + S D
Sbjct: 993 DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052
Query: 347 DCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDS 404
D ++DS SS S SDS S + S+ SD S + SSDS
Sbjct: 1053 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS-----DSSDSSDS 1105
Score = 47.0 bits (110), Expect = 5e-05
Identities = 60/248 (24%), Positives = 91/248 (36%), Gaps = 9/248 (3%)
Query: 161 DPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRH 220
D S ++SD++ +D +D S + + DS D + S S
Sbjct: 513 DDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSS 572
Query: 221 DSPDPSPPRRARHGSSDIS-SPRRVHNNSPDT--SRRTLGSSDTQQLRRARHDSPDLAPN 277
DS S + SSD S S +NS D+ S + SSD+ ++ DS +
Sbjct: 573 DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632
Query: 278 VTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQA-KSHF 336
+ S ++ S + SS S S +S+ S +S D S + S
Sbjct: 633 SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692
Query: 337 GDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRR 396
D D ++DSD S + DSDS S + + S SD S
Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS----- 747
Query: 397 QRTKSSDS 404
+ SSDS
Sbjct: 748 DSSNSSDS 755
Score = 47.0 bits (110), Expect = 5e-05
Identities = 67/287 (23%), Positives = 103/287 (35%), Gaps = 13/287 (4%)
Query: 122 DTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIR 181
++ DSS + + S D ++ D S D+ D S + + SD+S
Sbjct: 910 NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS--- 966
Query: 182 HDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSP 241
DSSD++ + + S +SS +S DS D S + + S +S
Sbjct: 967 -DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS 1025
Query: 242 RRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPH 301
+++ S + SSD+ DS D + + S S + SS +S
Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSD----SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081
Query: 302 WKESGASHLSFPKNSKYEYDP-DISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPR 360
+ S +S S +S D D S S D D ++DS SS
Sbjct: 1082 SESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 1141
Query: 361 HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLS 407
S + SDS S + SSDS S S+ SD S
Sbjct: 1142 SDSSDSSESSDSSDSSDSSD----SSDSSDSSDSSDSSDSSNSSDSS 1184
Score = 46.6 bits (109), Expect = 7e-05
Identities = 75/284 (26%), Positives = 101/284 (35%), Gaps = 33/284 (11%)
Query: 122 DTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIR 181
D+ DSS + D S D D+ + S ++ D S + + SD+S
Sbjct: 893 DSSDSS-NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS------ 945
Query: 182 HDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSP 241
DSSD+S + + S + NSS +S DS D S SSD SS
Sbjct: 946 -DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD-------SSD-SSD 996
Query: 242 RRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPH 301
+NS D SSD+ DS D + + S S + SS +S
Sbjct: 997 SSDSSNSSD-------SSDSS-------DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042
Query: 302 WKESGASHLSFPKNSKYEYD-PDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPR 360
S +S S NS D D S S D + D ++DS SS
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102
Query: 361 HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDS 404
S SDS S + S SD S + SSDS
Sbjct: 1103 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSDSSNSSDS 1144
Score = 46.6 bits (109), Expect = 7e-05
Identities = 72/267 (26%), Positives = 97/267 (36%), Gaps = 41/267 (15%)
Query: 122 DTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIR 181
D+ DSS + D S D D+ D S D+ D S + + SD+S
Sbjct: 1074 DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS------ 1127
Query: 182 HDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGS-SDISS 240
DSSD+S DS D S NSS +S DS D S + S S SS
Sbjct: 1128 -DSSDSS-------DSSDSS-------NSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1172
Query: 241 PRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSP 300
+NS D+S SSD+ DS D + + S S + SS +S
Sbjct: 1173 DSSDSSNSSDSS----DSSDSSD----SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1224
Query: 301 HWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPR 360
S ++ S +S D S + S DS D +DS S
Sbjct: 1225 SSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSS-------DSTSDSNDESDSQSKSGN 1277
Query: 361 HKQSPGHQDSDSDLSPPRNRPRHRSSD 387
+ DSDS+ S H +SD
Sbjct: 1278 GNNNGSDSDSDSEGSD----SNHSTSD 1300
Score = 45.8 bits (107), Expect = 1e-04
Identities = 70/311 (22%), Positives = 111/311 (35%), Gaps = 24/311 (7%)
Query: 107 GGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDP----SPRRARHDTPDP 162
G + D + + D+ DS + D S D D+ D S + D+ D
Sbjct: 533 GNDDNDKSDSGKGKSDSSDSD-------SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDS 585
Query: 163 SPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDS 222
+ DS S DSSD+S + S S + + +SS + + DS
Sbjct: 586 DSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKS---DS 642
Query: 223 PDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARH-----DSPDLAPN 277
D + + + S SS ++S D+S SSD+ + + DS D + +
Sbjct: 643 SDSNSSDSSDNSDSSDSSNSSNSSDSSDSS----DSSDSSSSSDSSNSSDSSDSSDSSNS 698
Query: 278 VTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYD-PDISPPRKKQAKSHF 336
S S +S ++ + +S +S+ S +S D D S S
Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758
Query: 337 GDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRR 396
D D ++DS SS + SDS S + + S SD S
Sbjct: 759 SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDS 818
Query: 397 QRTKSSDSDLS 407
+ SSDS S
Sbjct: 819 DSSNSSDSSNS 829
Score = 43.9 bits (102), Expect = 4e-04
Identities = 69/288 (23%), Positives = 100/288 (34%), Gaps = 16/288 (5%)
Query: 122 DTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGA-RHDSDTSPPRRI 180
++ D+S + D S D ++ D S ++ D S + DS S
Sbjct: 928 NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSD 987
Query: 181 RHDSSDTSPPRRARH--DSPDPSPPRRPQH--NSSGASPRRVRHDSPDPSPPRRARHGSS 236
DSSD+S + + DS D S + +SS +S DS D S + S
Sbjct: 988 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047
Query: 237 DISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASS 296
S +++ S + SSD+ DS D + + S S + SS
Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSSDSSD----SSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103
Query: 297 KTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDL 356
+S S +S S NS D S + S D D ++DS
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS--SDSSDSSESSDSSDSSDSSD 1161
Query: 357 SSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDS 404
SS S SDS S + S SD S + SSDS
Sbjct: 1162 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS-----DSSDSSDS 1204
Score = 33.1 bits (74), Expect = 0.78
Identities = 30/135 (22%), Positives = 45/135 (33%), Gaps = 5/135 (3%)
Query: 283 PRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQL 342
P KS + S T G F S DP+ S ++
Sbjct: 426 PGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNS 485
Query: 343 DSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRP-----RHRSSDSDLSPPRRRQ 397
S+GD +D + S G +D DSD + N + +D + +
Sbjct: 486 SSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKG 545
Query: 398 RTKSSDSDLSPPRRS 412
++ SSDSD S S
Sbjct: 546 KSDSSDSDSSDSSNS 560
Score = 30.4 bits (67), Expect = 5.0
Identities = 28/99 (28%), Positives = 36/99 (36%), Gaps = 5/99 (5%)
Query: 321 DPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNR 380
D D S K ++ S D + D ++DSD S S DSDS S +
Sbjct: 536 DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSD-----SNSSSDSDSSDSDSSDS 590
Query: 381 PRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKA 419
SSDS S S SD S S+ K+
Sbjct: 591 SDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS 629
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 57.4 bits (137), Expect = 4e-08
Identities = 114/504 (22%), Positives = 180/504 (35%), Gaps = 96/504 (19%)
Query: 174 TSPPRR----IRHDSSDTSP---PRRARHDSPDPSPPRRPQHNSSGASP--RRVRHDSPD 224
T PP + + H SS P P H SP +P + P H S + P + D
Sbjct: 513 TCPPLQPHPGLHHQSSPPHPHHQPWAQLHPSPQNTPQKVPVHQHSPSEPFLEKPVPDMTQ 572
Query: 225 PSPPRRARHGSSDI---------SSPRRVHNN---SPDTSRRT-----LGSSDTQQLRRA 267
S P S D ++ NN + D S+ G D Q+L R
Sbjct: 573 VSGPNAQLVKSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKGFGKDDFPGGVDNQELNRN 632
Query: 268 RHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPP 327
D K K P+ K P KE PK K P P
Sbjct: 633 SLDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEP--KE--------PKTPKAPKIP--KEP 680
Query: 328 RKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHK----QSPGHQDSDSDLSPPRNRPRH 383
++K+AK+ K SK K DS+ S+ + K ++ G ++SD D +PP + P
Sbjct: 681 KEKKAKT--ATPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSPPPE 738
Query: 384 RSSDSDLSPPR--RRQRTKSSDSDLS-PPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQ 440
D + R R+ + K DL + AA S + T Q EQQ
Sbjct: 739 EDEDPGVQKRRSSRQVKRKRYTEDLEFKISDEEADDADAAGRDSPSNTS------QSEQQ 792
Query: 441 ELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWG-- 498
E + +AE E + +S +K+ E +E K L+ QW
Sbjct: 793 E---------SVDAEGPVVEKIMSSRSVKKQKESGEEVEIEEFYVKYKNFSYLHCQWASI 843
Query: 499 KGLAQSRQQQQNVED-AMKEMQKPLARYIDDE-------DLDRML---REQEREGDPMAN 547
+ L + ++ QQ ++ K+ Q I+DE ++DR++ R + G+P+ +
Sbjct: 844 EDLEKDKRIQQKIKRFKAKQGQNKFLSEIEDELFNPDYVEVDRIMDFARSTDDRGEPVTH 903
Query: 548 FIKK-----------------NKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRS 590
++ K ++AK + +K+ R P R P W + S
Sbjct: 904 YLVKWCSLPYEDSTWERRQDIDQAKIEEFEKLMSR----EPETERVERPPADDWKKSESS 959
Query: 591 NGFEQKRFARLASKKAVEELAYKW 614
++ R + V L + W
Sbjct: 960 REYKNNNKLREYQLEGVNWLLFNW 983
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 56.2 bits (134), Expect = 9e-08
Identities = 98/528 (18%), Positives = 185/528 (35%), Gaps = 56/528 (10%)
Query: 60 AISTTKLEKEEEEDDGDLPVVAEFVDER----PEEVKQMEAFRSSAKWKLLGGHNEDLPS 115
A S K K +++ P A+ ++ P EVK E +S AK + P
Sbjct: 509 AASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPE 568
Query: 116 NRHFRHDTPDSSPRRVRHGTPD----PSPRKDRHDTPDPSPRRARHDTPDPSPLR-GARH 170
+ SP + + + P+ K P A+ SP++ A+
Sbjct: 569 KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKS 628
Query: 171 DSDTSPPRRIRHDS-SDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPD--PSP 227
++ P + + + + P +A+ SP+ + P+ SP + SP+ SP
Sbjct: 629 PAEVKSPEKAKSPTKEEAKSPEKAK--SPEKEEAKSPE---KAKSPVKAEAKSPEKAKSP 683
Query: 228 PRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKS 287
+ SP + SP+ ++ + + SP+ A + P +
Sbjct: 684 VKAEAKSPEKAKSPVKEEAKSPEKAKSPV---------KEEAKSPEKAKS-----PVKEE 729
Query: 288 GKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGD 347
K PE+A S K + + P+ P K++A+S DK +K
Sbjct: 730 AKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSP-ADKFPEKAKSP 788
Query: 348 CQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLS 407
++ ++ SP +SP +D+ +P + P+ S + + Q K +
Sbjct: 789 VKE----EVKSPEKAKSPLKEDAK---APEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKK 841
Query: 408 PPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKS 467
P K K + + + E K++ E++ + + DK
Sbjct: 842 AEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKK 901
Query: 468 -----GRKRNLKLERLEQRRKAEK---------DSERDELYAQWGKGLAQSRQQQQNVED 513
++ K+E E + EK D++ E K A ++ E
Sbjct: 902 KVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEK 961
Query: 514 AMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKK 561
A K +KP ED + +E + P A +K+ + + K+ K
Sbjct: 962 AKKPEEKPKTEAKAKEDDKTLSKEPSK---PKAEKAEKSSSTDQKDSK 1006
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 56.2 bits (134), Expect = 9e-08
Identities = 89/421 (21%), Positives = 148/421 (35%), Gaps = 64/421 (15%)
Query: 108 GHNEDLPSNRHFRH--DTPDSSP-RRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSP 164
G N+ P H DT S P ++ R G +K +H R+ + DT + S
Sbjct: 641 GLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSS 700
Query: 165 LRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDP------SPPRRPQHNSSGASPRRV 218
+ + +R R + ++P R P+P +PPRR + + R +
Sbjct: 701 -KAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSL 759
Query: 219 RHDSPDPSPPRRARHGSSDISSPRRVHNNS--PDTSRRTLG------SSDTQQLRRARHD 270
+ GSS R H P + +R G SS Q D
Sbjct: 760 PAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDED 819
Query: 271 SPDLAPNVTYSLPRTK---------SGKAPERASSKTSPHWKESGASHLSFPKNSKYEYD 321
S D + + + ++ SG R+ S++ +S S+ +S D
Sbjct: 820 SDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSD 879
Query: 322 PDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLS--------SPRHKQSPGHQDSDSD 373
++ + + D S+ +++ DSD S S RHK S D D
Sbjct: 880 QSCYSRQRSYSDDSYSDYSDR-SRRHSKRSHDSDDSDYASSKHRSKRHKYS--SSDDDYS 936
Query: 374 LSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLT 433
LS ++R R RS + R R R +S S S R + AH +
Sbjct: 937 LSCSQSRSRSRSHTRE----RSRSRGRSRSSSCSRSRSKRRSRSTTAHSW---------- 982
Query: 434 DIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDEL 493
QR + +++ + T + + RKR+ E E+R +D R ++
Sbjct: 983 --QRSRSYSRDRSRST----------RSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKI 1030
Query: 494 Y 494
Y
Sbjct: 1031 Y 1031
Score = 47.0 bits (110), Expect = 5e-05
Identities = 95/404 (23%), Positives = 144/404 (35%), Gaps = 50/404 (12%)
Query: 125 DSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLR-------------GARHD 171
+ P+ G+ P+P + R D S RR+ S + G +H
Sbjct: 728 ERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHK 787
Query: 172 SDTSPPRRIRHD-------SSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPD 224
+ P R SS S P DS D S R Q + S S DS
Sbjct: 788 GELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGS 847
Query: 225 PSPPRRARHGSSDIS--SPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSL 282
R+R G S S RR +++S D S SD R R S D +YS
Sbjct: 848 EHSRSRSRSGRRHSSHRSSRRSYSSSSDAS------SDQSCYSRQRSYSDD-----SYSD 896
Query: 283 PRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEY-DPDIS---PPRKKQAKSHFGD 338
+S + +R+ + S H S K KY D D S + +++SH +
Sbjct: 897 YSDRSRRHSKRSHDSDDSDYASS--KHRS--KRHKYSSSDDDYSLSCSQSRSRSRSHTRE 952
Query: 339 KKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQR 398
+ + S+G + ++ S S R +S S R+R R S S S R+R
Sbjct: 953 RSR--SRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSW 1010
Query: 399 TKSSDSDLSPPRRSQPPGK----KAAHMY-SGAKTGLVLTDIQR--EQQELKEQDQETMA 451
S + RR K ++ H + SG G D R + + Q +
Sbjct: 1011 GHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNI 1070
Query: 452 FEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYA 495
+ DK+ L LE+++ R+ K S +E+ A
Sbjct: 1071 GTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQA 1114
Score = 40.4 bits (93), Expect = 0.005
Identities = 68/353 (19%), Positives = 119/353 (33%), Gaps = 48/353 (13%)
Query: 254 RTLGSSDTQQLRRARHDSPDLAPNVT-YSLPRTKSGK--APERASSKTSPHWKESGASH- 309
+ +GSS L+ P+ + V + R+ G+ AP S+ + + +E G SH
Sbjct: 593 KDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHG 652
Query: 310 -------LSFPKNSKYEYDPDISPPRKKQAKSHFGDKK-QLDSKGDCQKATDSDLSSPRH 361
S P + +KK KS +K + D++ KA + S R
Sbjct: 653 SETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRK 712
Query: 362 KQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKK--- 418
K+ S + R +PPRRR+R + S P GKK
Sbjct: 713 KRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEG 772
Query: 419 ----AAHMYSGAK---------------TGLVLTDIQREQQELKEQDQETMAF-----EA 454
++ + G K T R Q ++D + + ++
Sbjct: 773 GGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKS 832
Query: 455 EFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDA 514
QY+E + SG + + R +R + + S R + +Q++ D
Sbjct: 833 PSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSD- 891
Query: 515 MKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKKVRPRYS 567
Y D D R ++ + D K+++K +K YS
Sbjct: 892 --------DSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYS 936
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 56.2 bits (134), Expect = 9e-08
Identities = 116/485 (23%), Positives = 167/485 (34%), Gaps = 93/485 (19%)
Query: 25 DRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTAISTTKLEKEEEEDD----GDLPVV 80
DR E R++ K +PKP R + A + ++++ +E D P
Sbjct: 469 DRDREKEREKEKGKPKPRSPQPPS-RQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKK 527
Query: 81 AEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDP-S 139
V P ++ +S+ N S+R + SS R R + S
Sbjct: 528 KLGVSVSPSRARRRRKTSASSA----SASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYS 583
Query: 140 PRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRR--IRHDSSDTSPPRRARHDS 197
R RH + S R+R + PSP S T P R IR PP +A S
Sbjct: 584 SRSSRHSSFSGSRSRSRSFSSSPSP-------SPTPSPHRPSIRTKGEPAPPPGKAGEKS 636
Query: 198 -----PDPSPPRR-------PQHNSSGASPRRVRHDSPDPSPPRR-----ARHGSSDISS 240
P P+PP+ P+ G R + P +PPRR + GS S
Sbjct: 637 VKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYS 696
Query: 241 PRRVHNNSPDTSRRTLGSSDTQQLRRARH-DSPDLAPNVTYSLPRTKS-GKAPERASSKT 298
+ S S + SS T A DS D+ ++ + S AP + +
Sbjct: 697 GSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEK 756
Query: 299 SPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKK-------QLDSKGDCQKA 351
KE G K K + D PP K AK G K Q G Q+
Sbjct: 757 GKSKKEDGV------KEEKRKRDSSTQPP--KSAKPPAGGKSSQQPSTPQQAPPGQPQQG 808
Query: 352 T--------------DSDLSSPRHKQSPGHQDSDSDLSPPRNRP--------RHRSSDSD 389
T +D S R + P +D S PP RP R R S
Sbjct: 809 TFVAHKEIKLTLLNKAADKGS-RKRYEPSDKDRQSP--PPAKRPNTSPDRGSRDRKSGGR 865
Query: 390 LSPPR-RRQRTKSSDSDLSPPRRSQP--------------PGKKAAHMYSGAKTGLVLTD 434
L P+ RQR ++S + +P R + PGK + + K+G T
Sbjct: 866 LGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKASTL 925
Query: 435 IQREQ 439
+RE+
Sbjct: 926 SRREE 930
Score = 35.8 bits (81), Expect = 0.12
Identities = 26/104 (25%), Positives = 50/104 (48%), Gaps = 14/104 (13%)
Query: 469 RKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDD 528
R+R + ER ++R+ E++ ERD + + + R+ +++ E ++ + R D
Sbjct: 402 RERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRD 461
Query: 529 EDLDRMLREQEREGDPMANFIKKNKAKENKNKKVRPRYSGPAPP 572
E DR R+++RE KE + +K +P+ P PP
Sbjct: 462 EK-DRQHRDRDRE-------------KEREKEKGKPKPRSPQPP 491
Score = 32.7 bits (73), Expect = 1.0
Identities = 52/251 (20%), Positives = 98/251 (39%), Gaps = 41/251 (16%)
Query: 319 EYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPR 378
E DP SP ++Q + D DS +D DL + S + + P +
Sbjct: 8 ERDPH-SPEDEEQPQGLSDDDILRDS------GSDQDLDGAGVRASDLEDEESAARGPSQ 60
Query: 379 NRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQRE 438
+ S + D R KS D D S+ P +D++ E
Sbjct: 61 EEEDNHSDEED-----RASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDE 115
Query: 439 QQEL-KEQDQETMAFEAEF--QYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDE-LY 494
+ +E D+ + ++ E + A V D++ ++ AE D E+ E
Sbjct: 116 ASSVTRELDEHELDYDEEVPEEPAPAVQEDEA------------EKAGAEDDEEKGEGTP 163
Query: 495 AQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKA 554
+ GK QS +++++E A ++ ++ IDD ++D + +++ +
Sbjct: 164 REEGKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEID-------------DDDLEEGEV 210
Query: 555 KENKNKKVRPR 565
K+ ++KVRPR
Sbjct: 211 KDPSDRKVRPR 221
Score = 30.0 bits (66), Expect = 6.6
Identities = 23/115 (20%), Positives = 44/115 (38%), Gaps = 17/115 (14%)
Query: 329 KKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDS 388
+++AK D++ D + ++ + PR Q P Q P+ + +D
Sbjct: 455 RERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADE 514
Query: 389 -----------------DLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGA 426
+SP R R+R K+S S S S+ + +++ SG+
Sbjct: 515 WKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGS 569
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 55.5 bits (132), Expect = 1e-07
Identities = 54/193 (27%), Positives = 75/193 (38%), Gaps = 11/193 (5%)
Query: 111 EDLPSNR-HFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGAR 169
ED+P H H S + RH PSP+ +RH T S + RH P SP
Sbjct: 1795 EDVPKKTTHRPHPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERH--PPVSPSSKTE 1852
Query: 170 HDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPR 229
S SP + S +S + +H SP SP + + +S +S + RH PS
Sbjct: 1853 KHSPVSPSAKTERHSPASSSSKTEKH-SP-VSPSTKTERHSPVSSTKTERHPPVSPSGKT 1910
Query: 230 RARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGK 289
R S + SP + + L S + R +H A LP + SGK
Sbjct: 1911 DKRPPVSPSGRTEKHPPVSPGRTEKRLPVSPSG--RTDKHQPVSTAGKTEKHLPVSPSGK 1968
Query: 290 A----PERASSKT 298
P +SKT
Sbjct: 1969 TEKQPPVSPTSKT 1981
Score = 34.7 bits (78), Expect = 0.27
Identities = 77/331 (23%), Positives = 119/331 (35%), Gaps = 62/331 (18%)
Query: 196 DSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRT 255
DS + SP + NSS +P DS +PSP + + S SSP P
Sbjct: 2435 DSLEASPVL--EDNSSHKTP-----DSLEPSPLKESPCRDSLESSPVE-----PKMKAGI 2482
Query: 256 LGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLS--FP 313
S A+ + +V L R G A + + +TS + SG S LS P
Sbjct: 2483 FPSHFPLPAAVAKTELLTEVASVRSRLLRDPDGSAEDDSLEQTSL-MESSGKSPLSPDTP 2541
Query: 314 KNSKYEYD-----PDISPPRK-------KQAKSHFGDKKQLDSKGDCQKATDSDL----- 356
+ + Y+ D+S P+ ++ S G+KK+ + + K
Sbjct: 2542 SSEEVSYEVTPKTTDVSTPKPAVIHECAEEDDSENGEKKRFTPEEEMFKMVTKIKMFDEL 2601
Query: 357 -----------SSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSP----PRRRQRTKS 401
P+ ++S D D+D S + P+H S D S R S
Sbjct: 2602 EQEAKQKRDYKKEPKQEESSSSSDPDADCSVDVDEPKHTGSGEDESGVPVLVTSESRKVS 2661
Query: 402 SDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQEL---KEQDQETMAFEAEFQY 458
S S+ P + A + GA +GL+ + R Q D + E +FQ
Sbjct: 2662 SSSESEP---------ELAQLKKGADSGLLPEPVIRVQPPSPLPSSMDSNSSPEEVQFQ- 2711
Query: 459 AETVFRDKSGRKRNLKLERLEQRRKAEKDSE 489
V + K N + + + EKDSE
Sbjct: 2712 --PVVSKQYTFKMNEDTQEEPGKSEEEKDSE 2740
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 54.7 bits (130), Expect = 2e-07
Identities = 68/257 (26%), Positives = 105/257 (40%), Gaps = 53/257 (20%)
Query: 11 EYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA------ISTT 64
EY++R S + E GRK++K R K G + D + +S
Sbjct: 113 EYIEREESDGEY-----DEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKY 167
Query: 65 KLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTP 124
KL+++E+EDD DL E + K+ RS +K + + H R +
Sbjct: 168 KLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSR-----------SSHSRSSSR 216
Query: 125 DSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDT------SPPR 178
SSP R S + R + S R+R + + S RG++ S + S PR
Sbjct: 217 SSSPSSSR------SRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR 270
Query: 179 RIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSG-ASPRRVRHDSPDPSPPRRARHGSSD 237
+ + SS +SP R + R + +SSG RR R SP+ RH SS
Sbjct: 271 KRSYSSSSSSPERNRKRS--------RSRSSSSGDRKKRRTRSRSPE------RRHRSSS 316
Query: 238 ISSPRRVHNNSPDTSRR 254
SS H+ S +S++
Sbjct: 317 GSS----HSGSRSSSKK 329
Score = 39.7 bits (91), Expect = 0.008
Identities = 43/161 (26%), Positives = 69/161 (42%), Gaps = 13/161 (8%)
Query: 270 DSPDLAP-NVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPR 328
D DL+ N+ S + K R S S +S S P +S+
Sbjct: 176 DDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS 235
Query: 329 KKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQD-SDSDLSPPRNRPRHRSSD 387
Q++S +++ S+G +++ S R SP + S S SP RNR R RS
Sbjct: 236 SSQSRSRSSSRERSRSRGSKSRSSSR---SHRGSSSPRKRSYSSSSSSPERNRKRSRSRS 292
Query: 388 SDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKT 428
S S R+++RT+S SP RR + + +SG+++
Sbjct: 293 SS-SGDRKKRRTRSR----SPERRHR---SSSGSSHSGSRS 325
Score = 35.0 bits (79), Expect = 0.20
Identities = 41/165 (24%), Positives = 61/165 (36%), Gaps = 17/165 (10%)
Query: 158 DTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPP-----RRPQHNSSG 212
D D S + + S ++ S S +R S SP R + SS
Sbjct: 176 DDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS 235
Query: 213 ASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSP 272
+S R R S + R+R S S R H S +R+ SS + R +
Sbjct: 236 SSQSRSRSSSRE-----RSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRS 290
Query: 273 DLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSK 317
+ + RT+S ++PER H SG+SH +SK
Sbjct: 291 RSSSSGDRKKRRTRS-RSPERR------HRSSSGSSHSGSRSSSK 328
Score = 33.1 bits (74), Expect = 0.78
Identities = 39/199 (19%), Positives = 70/199 (35%), Gaps = 9/199 (4%)
Query: 314 KNSKYEYDPDISPPRKKQAKSHFGDK---KQLDSKGDCQKATDSDLSSPRHKQSPGHQDS 370
+ S EYD + +KK G K+++ K + D D ++K +
Sbjct: 118 EESDGEYD-EFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDED 176
Query: 371 DSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGL 430
D+DLS N DS+ RR R+KS S RS P + S +++
Sbjct: 177 DADLSK-YNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS 235
Query: 431 VLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSER 490
R + + + + + + + + S RKR+ R ++ R
Sbjct: 236 SSQSRSRSSSRERSRSRGSKSRSSSRSHRGS----SSPRKRSYSSSSSSPERNRKRSRSR 291
Query: 491 DELYAQWGKGLAQSRQQQQ 509
K +SR ++
Sbjct: 292 SSSSGDRKKRRTRSRSPER 310
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 53.9 bits (128), Expect = 4e-07
Identities = 77/425 (18%), Positives = 151/425 (35%), Gaps = 39/425 (9%)
Query: 24 VDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTAISTTKLEKEEEEDDGDLPVVAEF 83
V R + +G + +++P GG+ R + A K EK+++E + + A
Sbjct: 379 VHRCAPAGERGERRKPNAGGSPAPVRRRPE------ASPVQKKEKKDKERENEKEKSAL- 431
Query: 84 VDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPR-- 141
R +K+ ++ +S + +L +L R +P +S R P P P
Sbjct: 432 --ARERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHT 489
Query: 142 ------KDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSP--PRRA 193
R T P R R + SP D S RR ++ +P P +
Sbjct: 490 LPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSK-RRASNEKESAAPASPAPS 548
Query: 194 RHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSP---PRRARHGSSDISSPRRVHNNSPD 250
SP P+PP++ Q + + V P P+P P + G++D R+
Sbjct: 549 PAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRR 608
Query: 251 TSRRTLGSSDTQQLRRARHD----SPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESG 306
+R + ++ +A D LA R + E ++ ++
Sbjct: 609 QAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEE 668
Query: 307 ASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGD------CQKATDSDLSSPR 360
L K + + ++ + + HF ++Q + ++ S++S +
Sbjct: 669 QERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETK 728
Query: 361 HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAA 420
KQ +++ P R SP +++ + + P+ S P + A
Sbjct: 729 QKQDSKEANANGSSPEPVKAVEAR------SPGLQKEAVQKEEPIPQEPQWSLPSKELPA 782
Query: 421 HMYSG 425
+ +G
Sbjct: 783 SLVNG 787
Score = 45.1 bits (105), Expect = 2e-04
Identities = 88/439 (20%), Positives = 155/439 (35%), Gaps = 72/439 (16%)
Query: 190 PRRARHDSPDPSPPRRPQHNSSGAS------PRRVRHDSPDPSPPRRARHGS-SDISSPR 242
PR R P R P +GAS P R + P PR A + S R
Sbjct: 318 PRNGRDQGRGCDPGRGPTWGRAGASLARGPQPDRTHPSAAVPVCPRSASASPLTPCSVTR 377
Query: 243 RVHN----------------NSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTK 286
VH SP RR +S Q ++ + D +L R +
Sbjct: 378 SVHRCAPAGERGERRKPNAGGSPAPVRRRPEASPVQ--KKEKKDKERENEKEKSALARER 435
Query: 287 SGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDIS-----------------PPRK 329
S K + + S AS LS PK+ P S PP+
Sbjct: 436 SLKKRQSLPASPRARLSASTASELS-PKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKP 494
Query: 330 KQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSD 389
+ K + + K + S QS ++ + + P + +
Sbjct: 495 PSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPT 554
Query: 390 LSPPRRRQRTKSSDSDL----SPPRRSQP--PGKKAAHMYSGAKTGLVLTDIQREQQELK 443
+PP++ Q + +D SPP + P P K A + +L + +R+ +E +
Sbjct: 555 PAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQR 614
Query: 444 EQDQETMAFEAEFQYA---ETVFRDKSGR-KRNLKLERLEQRRKAEK----DSERDELYA 495
E++++ +AE E + R+ R +R + R E++ EK E++ L
Sbjct: 615 EREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQK 674
Query: 496 QWGKGLAQSR---------------QQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQER 540
Q + A+SR QQ+Q ++ K +++ + R E + ++ +
Sbjct: 675 QKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSK 734
Query: 541 EGDPMANFIKKNKAKENKN 559
E + + + KA E ++
Sbjct: 735 EANANGSSPEPVKAVEARS 753
Score = 43.9 bits (102), Expect = 4e-04
Identities = 50/228 (21%), Positives = 84/228 (36%), Gaps = 30/228 (13%)
Query: 283 PRTKSGK-APERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQ 341
PR + G AP ++T P + S S P PD +PP A + KQ
Sbjct: 5 PRAELGAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPD-TPPDTPPAMKNATSSKQ 63
Query: 342 LDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKS 401
L + + +P ++SP + +PP PR
Sbjct: 64 LPLEPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPR------------------- 104
Query: 402 SDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAET 461
D PPRRS P A T + + KE+ +E + A +
Sbjct: 105 ---DARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKYLAA---KKA 158
Query: 462 VFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQ 509
V+ +K + + L+ ++L++RR+ E L A+ + + RQ+Q+
Sbjct: 159 VWLEKEEKAKALREKQLQERRRR---LEEQRLKAEQRRAALEERQRQK 203
Score = 39.7 bits (91), Expect = 0.008
Identities = 29/125 (23%), Positives = 48/125 (38%), Gaps = 2/125 (1%)
Query: 148 PDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQ 207
P+P P +P P P+ D+ P +++ +S P S P P
Sbjct: 23 PEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPAPP 82
Query: 208 HNSSGASPRRVRHDSPDPSPPRRAR--HGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLR 265
S +S + R +P PR AR SS S ++SP T + + + +L
Sbjct: 83 QEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLA 142
Query: 266 RARHD 270
+ R +
Sbjct: 143 KERRE 147
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 53.5 bits (127), Expect = 6e-07
Identities = 113/503 (22%), Positives = 173/503 (34%), Gaps = 77/503 (15%)
Query: 88 PEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTP-DPSPRKDRHD 146
PE + +W+ G +ED R R D + PRR+ +PS R D
Sbjct: 903 PEADSEWRRGPPEKEWRRGEGRDED----RSHRRD--EERPRRLGDDEDREPSLRPDDDR 956
Query: 147 TP------DPSPRRARHDTPDPSPLRGA-------RHDSDTSPPRRIRHD-------SSD 186
P D PRR + D RGA R+ D PPRRI + + D
Sbjct: 957 VPRRGMDDDRGPRRGPEE--DRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADD 1014
Query: 187 TSPPRRARHD-------SPDPSPPRRPQHNSSGASPRRVRHDSPDPS-----PPRRARHG 234
PPRR + + + PRR + G PRR D S R R G
Sbjct: 1015 DRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRG--PRRGGADDERSSWRNADDDRGPRRG 1072
Query: 235 SSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPR-----TKSGK 289
D PRR ++ R G D + RR D D P R +
Sbjct: 1073 LDDDRGPRRGMDDDRGPRR---GMDDDRGPRRGMDD--DRGPRRGLDDDRGPWRNADDDR 1127
Query: 290 APERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKG--- 346
P R + W+ LS D D P R ++ G + L G
Sbjct: 1128 IPRRGAEDDRGPWRNMDDDRLS------RRADDDRFPRRGDDSRP--GPWRPLVKPGGWR 1179
Query: 347 DCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDL 406
+ +KA + PR +S ++ + D R+R ++D P R R R + D +
Sbjct: 1180 EKEKAREESWGPPR--ESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDRE- 1236
Query: 407 SPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDK 466
R + P + A+ D R ++ + + + + D+
Sbjct: 1237 ---DRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDR 1293
Query: 467 SGRKRNLKLERLE-------QRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQ 519
R L+ ER E RK ++ ERD L++ R++ ++ E ++ +
Sbjct: 1294 DRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEK 1353
Query: 520 KPLARYIDDEDLDRMLREQEREG 542
D E L R E + +G
Sbjct: 1354 ASWRAEKDRESLRRTKNETDEDG 1376
Score = 38.1 bits (87), Expect = 0.024
Identities = 39/174 (22%), Positives = 77/174 (44%), Gaps = 37/174 (21%)
Query: 427 KTGLVLTDIQREQQELKEQ----------DQETMAFEAEFQYAETVFRDKSGRKRNLKLE 476
K L +IQRE++EL+++ ++E + EA+ + E + ++ K+ E
Sbjct: 579 KERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRE 638
Query: 477 RLEQRRKAE------KDSERDELYAQ-----WGKGLAQSRQQQQNVEDAMKEMQKPL--- 522
RLEQ +K E KD + ++L K + Q ++++ +++ +K +K +
Sbjct: 639 RLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYF 698
Query: 523 -------------ARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKKVR 563
+ Y + D L EQ+ E +++ KA E+KN+ R
Sbjct: 699 ERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSR 752
Score = 33.9 bits (76), Expect = 0.46
Identities = 20/66 (30%), Positives = 37/66 (56%), Gaps = 5/66 (7%)
Query: 436 QREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEK---DSERDE 492
+RE+ E ++++E ++ + E V R K R+R L++E E+RR+ E+ DS
Sbjct: 828 ERERAERAKREEELREYQERVKKLEEVERKK--RQRELEIEERERRREEERRLGDSSLSR 885
Query: 493 LYAQWG 498
++WG
Sbjct: 886 KDSRWG 891
Score = 31.6 bits (70), Expect = 2.3
Identities = 25/104 (24%), Positives = 44/104 (42%), Gaps = 15/104 (14%)
Query: 440 QELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGK 499
+E K Q +E E Y ++ R L+ E+R +AE+ +EL
Sbjct: 792 EERKRQRKE----ERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEEL------ 841
Query: 500 GLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGD 543
R+ Q+ V+ + +K R ++ E+ +R E+ R GD
Sbjct: 842 -----REYQERVKKLEEVERKKRQRELEIEERERRREEERRLGD 880
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 53.1 bits (126), Expect = 7e-07
Identities = 84/425 (19%), Positives = 157/425 (36%), Gaps = 46/425 (10%)
Query: 153 RRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSG 212
R ++P L A D+D R R + +R D RR + +
Sbjct: 30 RPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHR 89
Query: 213 ASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGS--------SDTQQL 264
R R D R + + N + R T +D Q+
Sbjct: 90 KRDRH-RERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRE 148
Query: 265 RRARHDSPDLAPNVT--YSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDP 322
R + D+ T +T+ + ER K +E K +
Sbjct: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSER 208
Query: 323 DISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPR 382
R+++ ++ K+Q D + D Q+ T+ + R KQ+ + S+ + + R R
Sbjct: 209 GRERERERETETETERKRQTDRERDRQRKTERE----REKQAERERASERETERDKERER 264
Query: 383 HRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQEL 442
R D D RRQ+ + +D RR++ + T+ +RE+Q
Sbjct: 265 ERDRDRDRD---RRQKERERQTDRKRQRRTERDRE---------------TERKRERQRE 306
Query: 443 KEQDQE-TMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGL 501
+E+++E E E + R + + K +++R+ E D ER+ Q G+
Sbjct: 307 RERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNR---QTGR-- 361
Query: 502 AQSRQQQQNVEDAMKEMQKPLARYIDDEDLDR-MLREQEREGDPMANFIKKNKAKENKNK 560
+ R+Q + + +E + AR ++ + DR R++ERE +K++ + + +
Sbjct: 362 -EGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ-----TEKDRDGQRETE 415
Query: 561 KVRPR 565
K R R
Sbjct: 416 KQRER 420
Score = 47.0 bits (110), Expect = 5e-05
Identities = 80/466 (17%), Positives = 169/466 (36%), Gaps = 52/466 (11%)
Query: 98 RSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRK-DRHDTPDPSPRRAR 156
+ S + + LG ++D + R+ + RR + T + RK +R D +R R
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
Query: 157 HDTPDPSPLRGARHDSDTSPPR-----RIRHDSSDTSPPR---RARHDSPDPSPPRRPQH 208
H + +D R R R + R R R D R Q
Sbjct: 94 HRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153
Query: 209 NSSGASPRRVRHDSPDPSPPRRARHGSSDIS-SPRRVHNNSPDTSRRTLGSSDTQQLRRA 267
++ R+ + + R + + + RR + +T + R
Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERE 213
Query: 268 RHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPP 327
R + R + + + + + K + E D D
Sbjct: 214 RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD 273
Query: 328 RKKQAKSHFGDKK-QLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSS 386
R+++ + D+K Q ++ D + + R ++ ++ + + R R R R +
Sbjct: 274 RRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRET 333
Query: 387 DSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQD 446
+ D R R+R + ++ D R++ G++ A +RE++ +E+D
Sbjct: 334 ERDREKERERKRKRQTEMDRERNRQTGREGRRQA---------------ERERERERERD 378
Query: 447 QETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQR-RKAEKDSERDELYAQWGKGLAQSR 505
+++ R++ R+R+ +R ++R R+ EKD + G ++
Sbjct: 379 RQSA-------------REREERERDRDRDRQKERERQTEKDRD----------GQRETE 415
Query: 506 QQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKK 551
+Q++ +D +E ++ R + E R++ER+ D A +K
Sbjct: 416 KQREREKD--RESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
Score = 31.2 bits (69), Expect = 3.0
Identities = 86/411 (20%), Positives = 131/411 (31%), Gaps = 30/411 (7%)
Query: 25 DRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTAISTTKLEKEEE-EDDGDLPVVAEF 83
DR E R R+K+R + G+ R D EKE E + D + E
Sbjct: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173
Query: 84 VDERPEE-VKQMEAFRSSAKWKLLGGHNEDLPSNR-----HFRHDTPDSSPRRVRHGTPD 137
++ E K + R + + ED S R R ++ +R D
Sbjct: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD 233
Query: 138 PSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDS 197
+ +R RA + R D D RR + T R+ R +
Sbjct: 234 RQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTER 293
Query: 198 PDPSPPRRPQHNSSGASPRRVRHDSPDPSPPR---RARHGSSDISSPR---RVHNNSPDT 251
+ +R + R R + R R R D R R D
Sbjct: 294 DRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDR 353
Query: 252 SR-RTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHL 310
R R G +Q R R + R + + ER + KE
Sbjct: 354 ERNRQTGREGRRQAERERERERER--------DRQSAREREERERDRDRDRQKER---ER 402
Query: 311 SFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDS 370
K+ + + + R+K +S G ++ + + QK + D +Q+ G Q
Sbjct: 403 QTEKDRDGQRETEKQREREKDRESERG--RERGREREKQKGRERDRERQTDRQA-GRQRK 459
Query: 371 DSDL--SPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKA 419
S L +PP R SD + P R R KSS D P G+ A
Sbjct: 460 RSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPA 510
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 53.1 bits (126), Expect = 7e-07
Identities = 80/386 (20%), Positives = 126/386 (32%), Gaps = 38/386 (9%)
Query: 135 TPDPSPRKDRHDTPDPSPRRARHDTPDPSPLR------GARHDSDTSPPRRIRHDSSDTS 188
TP PS R + +R R + PSP++ +H S ++ RH SS
Sbjct: 101 TPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPK 160
Query: 189 PPRR--ARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHN 246
RR RH S PR+ + P R + PS G S +
Sbjct: 161 SKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRR 220
Query: 247 NSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESG 306
+S S+ S Q R + ++ T SG A + + SP G
Sbjct: 221 HSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRG 280
Query: 307 ASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPG 366
++ +Y+ D S P Q S S+G + + LS R S
Sbjct: 281 -------RSQEYDSGNDTSSPPSTQTSS-------ARSRGQEKGSPSGGLSKSRELNSGN 326
Query: 367 HQDSDSDL--SPPRNR----------PRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQP 414
DS + S P+N+ R R S SP K S S R S
Sbjct: 327 TSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPM 386
Query: 415 PGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRK---- 470
G + Y+ ++ + + + + + E + KSG++
Sbjct: 387 KGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPS 446
Query: 471 RNLKLERLEQRRKAEKDSERDELYAQ 496
R+ + R + ERD Y++
Sbjct: 447 RSSRSRRSPSYSRYSPSRERDPKYSE 472
Score = 42.4 bits (98), Expect = 0.001
Identities = 74/290 (25%), Positives = 105/290 (36%), Gaps = 24/290 (8%)
Query: 147 TPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRP 206
T P + A + P+ RG SP + P AR SP +
Sbjct: 336 TSSPQNKGAMLENLSPTS-RGRESRGFQSPCLECAEVKKSSLVPSTARS-----SPMKGC 389
Query: 207 QHNSSGASPRRVRHDSPDPSPPRRARHGSS-DISSPRRVHNNSPDTSRRTLGSSDTQQLR 265
+SS AS R H S P+P R+ S SS +R ++ SP S ++ S +
Sbjct: 390 SRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSS 449
Query: 266 RARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPD-- 323
R+R SP + YS R + K E+ S + S P + P
Sbjct: 450 RSRR-SPSYS---RYSPSRERDPKYSEKDSQQRERERARRRRRSYS-PMRKRRRDSPSHL 504
Query: 324 ----ISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDS-DLSPPR 378
I+ RK+ + + S G + SS S + S S S R
Sbjct: 505 EARRITSARKRPIPYY---RPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRR 561
Query: 379 NRPRHRSSDSDLSP-PRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAK 427
+R R SS S SP P R R++S S RSQ +A YS +
Sbjct: 562 SRTRTSSSSSSRSPSPGSRSRSRSRSRSRS-RSRSQSRSYSSADSYSSTR 610
Score = 40.0 bits (92), Expect = 0.006
Identities = 54/253 (21%), Positives = 89/253 (35%), Gaps = 21/253 (8%)
Query: 159 TPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRV 218
T SP++G S + R H S +P R+ + + ++ S + +
Sbjct: 380 TARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKS 439
Query: 219 RHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNV 278
SP R R S SP R P S + + ++ RR R +
Sbjct: 440 GKRSPPSRSSRSRRSPSYSRYSPSR--ERDPKYSEKDSQQRERERARRRRRSYSPMRKRR 497
Query: 279 TYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGD 338
S P + A + P+++ S +S S S + S + ++S+
Sbjct: 498 RDS-PSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWY----SSSSSRSASRSYSRS 552
Query: 339 KKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQR 398
+ + S+ + T S SS +SP P +R R RS S R + R
Sbjct: 553 RSRSRSRRRSRTRTSSSSSS----RSPS----------PGSRSRSRSRSRSRSRSRSQSR 598
Query: 399 TKSSDSDLSPPRR 411
+ SS S RR
Sbjct: 599 SYSSADSYSSTRR 611
Score = 35.4 bits (80), Expect = 0.16
Identities = 45/184 (24%), Positives = 64/184 (34%), Gaps = 27/184 (14%)
Query: 123 TPDSSPRRVRHGTPDPSPRKDR---HDTPDPS----PRRARHDTPDPSPLRGARHDSDTS 175
+P S + + P S R R + PS P+ + D+ R R S
Sbjct: 432 SPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYS 491
Query: 176 PPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSG---------------ASPRRVRH 220
P R+ R DS RR P P RP +SSG ++ R
Sbjct: 492 PMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSR 551
Query: 221 DSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTY 280
RR+R +S SS R SP R+ S ++ R+R S + +Y
Sbjct: 552 SRSRSRSRRRSRTRTSSSSSSR-----SPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSY 606
Query: 281 SLPR 284
S R
Sbjct: 607 SSTR 610
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 53.1 bits (126), Expect = 7e-07
Identities = 78/321 (24%), Positives = 109/321 (33%), Gaps = 42/321 (13%)
Query: 123 TPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRH 182
TP ++P + G PSP K TP +P + PSP +GA +PP
Sbjct: 1197 TPAATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGLATPSP-KGAPTTPAATPPSP--- 1251
Query: 183 DSSDTSPPRRARHDSPDPSPPR------RPQHNSSGASPRRVRHDSPDPSPPRRARHGSS 236
+PP + P +PP P H + +P V SP P G+
Sbjct: 1252 KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA-PNPAVVTPPSPKGGPATSPPKGAP 1310
Query: 237 DISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASS 296
+P SP S T SP P + + P +K G P SS
Sbjct: 1311 ---TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG--PTTPSS 1365
Query: 297 KTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDL 356
K P + SH P ++PP K+ + KGD L
Sbjct: 1366 KEGPTPPAATPSHKG---------GPAMTPPSPKRGPAI------PSPKGDPTSPAVIPL 1410
Query: 357 SSPRHKQSPGHQD-----SDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSD-----L 406
S + +P ++ S DL+PP P S P+ T SS D +
Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV 1470
Query: 407 SPPRRSQPPGKKAAHMYSGAK 427
+PP +PP K S K
Sbjct: 1471 TPPSPKEPPAPKQVATSSSPK 1491
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 52.4 bits (124), Expect = 1e-06
Identities = 101/501 (20%), Positives = 167/501 (33%), Gaps = 99/501 (19%)
Query: 124 PDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDS-DTSPPRRIRH 182
P + P + TP + SP+ A+ SP+R + S + P R +
Sbjct: 258 PTAKPLETKSFTPKTKTKTSSPGQKTKSPKTAQSPAMVGSPIRSPKTVSKEKKSPGRSKS 317
Query: 183 DSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDS---------PDP------SP 227
S SP + H P P P S ++ ++ PD +
Sbjct: 318 PKSPKSP-KVTTHIPQTPVRPETPNRTPSATLSEKISKETIQVKQIQTPPDAGKLNSENQ 376
Query: 228 PRRAR------HGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRA--RHDSPDLA-PNV 278
P++A S D R PD + GS + + R P+ P
Sbjct: 377 PKKAVVADKTIEASIDAVIARACAEREPDPFEFSSGSESEGDIFTSPKRISGPECTTPKA 436
Query: 279 TYSLPR-TKSGKAPERASSKTSPH---W-----------KESGASHLSFPKNSKYEYDPD 323
+ S TKSG P S TS W K + + P N Y P
Sbjct: 437 STSANNFTKSGSTPLPLSGGTSSSDNSWTMDASIDEVVRKAKLGTPSNMPPNFPYISSPS 496
Query: 324 ISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRH 383
+SPP + + +K +L S + +K +L + K+ + R R
Sbjct: 497 VSPPTPEPLHKVYEEKTKLPSSVEVKKKLKKELKTKMKKKE-------------KQRDRE 543
Query: 384 RSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELK 443
R D + + + + K + D R ++ P K + LK
Sbjct: 544 REKDKNKDKSKEKDKVKEKEKDKETGRETKYPWK----------------------EFLK 581
Query: 444 EQDQETMAFE-AEFQYAETVFRDKSGRKRNLK---LERLEQRRKAEKDSERDELYAQWGK 499
E++ + F+ EF+ + + K G R K ++ + R K +KD ++ E K
Sbjct: 582 EEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDK 641
Query: 500 GLA-QSRQQQQNVEDAMKEMQKPLARYIDDEDLDRML------------------REQER 540
G + + + KE+ PL + ML +E+E+
Sbjct: 642 GREDKMKAPAPPLVLPPKELALPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEK 701
Query: 541 EGDPMANFIKKNKAKENKNKK 561
+ D KK K KE K K+
Sbjct: 702 KKDKKEKKKKKEKEKEKKEKE 722
Score = 42.7 bits (99), Expect = 0.001
Identities = 72/364 (19%), Positives = 123/364 (33%), Gaps = 64/364 (17%)
Query: 162 PSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHD 221
P PL G SD S D+S R+A+ +P PP P +S SP
Sbjct: 450 PLPLSGGTSSSDNSWTM----DASIDEVVRKAKLGTPSNMPPNFPYISSPSVSP------ 499
Query: 222 SPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYS 281
P P P + + + S V + + + Q R R D + +
Sbjct: 500 -PTPEPLHKVYEEKTKLPSSVEVKKKLKKELKTKMKKKEKQ---RDREREKDKNKDKSKE 555
Query: 282 LPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRK-KQAKSHFGDKK 340
+ K + + +T WKE + P K + D+ P K K +K
Sbjct: 556 KDKVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEK 615
Query: 341 QLDSKGDCQKAT-DSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRT 399
D K D +K D D + G +D +PP P +L+ P T
Sbjct: 616 HKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPPLVLP-----PKELALPLFSPAT 670
Query: 400 KSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYA 459
S + P P K + E++++KE+++
Sbjct: 671 ASRVPAMLPSLLPVLPEK-----------------LFEEKEKVKEKEK------------ 701
Query: 460 ETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQ 519
K ++ E+++K EK+ E+ E + K + R++++ K
Sbjct: 702 --------------KKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIKV 747
Query: 520 KPLA 523
+P+A
Sbjct: 748 EPVA 751
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 51.6 bits (122), Expect = 2e-06
Identities = 88/368 (23%), Positives = 123/368 (33%), Gaps = 52/368 (14%)
Query: 69 EEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNED--LPSNRHFRHDTPDS 126
E E DGD V P E + + K K G + S + S
Sbjct: 470 EAREADGD---VVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSS 526
Query: 127 SPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSD 186
+ V + S R + SP+R + + SP AR S RRI+ +S+
Sbjct: 527 TSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNR 586
Query: 187 TSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRR--- 243
R R S S R + N SP R R S S RR S S RR
Sbjct: 587 ARVKIRDRRRSNRNSIERERRRN---RSPSRERRRSRSRSRDRRTNRASRSRSRDRRKID 643
Query: 244 -VHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHW 302
N S + G + Q+ ++ R S D R K K ER K
Sbjct: 644 DQRGNLSGNSHKHKGEAKEQERKKERSRSID--------KDRKKKDKEREREQDKRKEKQ 695
Query: 303 KESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQL-------DSKGDCQKATDSD 355
K K+ K+ D RK++++ F + DS+ D +K+T D
Sbjct: 696 KRE-------EKDFKFSSQDD-RLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKD 747
Query: 356 LSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPP 415
S H SDS RSS + ++ K S +SQ
Sbjct: 748 --------SKKHSGSDSS---------GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRS 790
Query: 416 GKKAAHMY 423
GKKA+ +
Sbjct: 791 GKKASRKH 798
Score = 42.7 bits (99), Expect = 0.001
Identities = 54/237 (22%), Positives = 97/237 (40%), Gaps = 41/237 (17%)
Query: 328 RKKQAKSHFGDKKQLDSKGDCQ-KATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRH-RS 385
++KQ +S G S + + +T S +SS + S G + S S P+ + RH RS
Sbjct: 502 KEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRS 561
Query: 386 SDSDLSPPRRRQRTKSSDSDLSPPR-RSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKE 444
+ R R R+ S + R R + ++ ++ S I+RE++ +
Sbjct: 562 RSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNS----------IERERRRNRS 611
Query: 445 QDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQS 504
+E R +S +R + R R + + D +R L K ++
Sbjct: 612 PSRERRRS-----------RSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEA 660
Query: 505 RQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKK 561
++Q E +K +R I D+D + +E+ERE D K K K+ + +K
Sbjct: 661 KEQ---------ERKKERSRSI-DKDRKKKDKEREREQD-------KRKEKQKREEK 700
Score = 32.0 bits (71), Expect = 1.7
Identities = 53/264 (20%), Positives = 99/264 (37%), Gaps = 21/264 (7%)
Query: 163 SPLRGARHDSDT-SPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHD 221
S L D D + +R ++++ P++ H + R +SSG+S R
Sbjct: 467 SLLEAREADGDVVNEKKRTPNETTSVLEPKK-EHKEKEKQGRSRSGSSSSGSSSSNSRTS 525
Query: 222 SPDP-------SPPRRARHGSSDISSPRRVHNNSPDTS-----RRTLGSSDTQQLR---- 265
S S + SS SSP+R +S S RR+ S +++++
Sbjct: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESN 585
Query: 266 RARHDSPDLAPNVTYSLPR-TKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDI 324
RAR D + S+ R + ++P R ++ ++ + S ++ D
Sbjct: 586 RARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQ 645
Query: 325 SPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRP-RH 383
+ H G+ K+ + K + ++ D D + K+ QD + + +
Sbjct: 646 RGNLSGNSHKHKGEAKEQERKKERSRSIDKD-RKKKDKEREREQDKRKEKQKREEKDFKF 704
Query: 384 RSSDSDLSPPRRRQRTKSSDSDLS 407
S D L R +RT S +S
Sbjct: 705 SSQDDRLKRKRESERTFSRSGSIS 728
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 51.6 bits (122), Expect = 2e-06
Identities = 88/368 (23%), Positives = 123/368 (33%), Gaps = 52/368 (14%)
Query: 69 EEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNED--LPSNRHFRHDTPDS 126
E E DGD V P E + + K K G + S + S
Sbjct: 470 EAREADGD---VVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSS 526
Query: 127 SPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSD 186
+ V + S R + SP+R + + SP AR S RRI+ +S+
Sbjct: 527 TSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNR 586
Query: 187 TSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRR--- 243
R R S S R + N SP R R S S RR S S RR
Sbjct: 587 ARVKIRDRRRSNRNSIERERRRN---RSPSRERRRSRSRSRDRRTNRASRSRSRDRRKID 643
Query: 244 -VHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHW 302
N S + G + Q+ ++ R S D R K K ER K
Sbjct: 644 DQRGNLSGNSHKHKGEAKEQERKKERSRSID--------KDRKKKDKEREREQDKRKEKQ 695
Query: 303 KESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQL-------DSKGDCQKATDSD 355
K K+ K+ D RK++++ F + DS+ D +K+T D
Sbjct: 696 KRE-------EKDFKFSSQDD-RLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKD 747
Query: 356 LSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPP 415
S H SDS RSS + ++ K S +SQ
Sbjct: 748 --------SKKHSGSDSS---------GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRS 790
Query: 416 GKKAAHMY 423
GKKA+ +
Sbjct: 791 GKKASRKH 798
Score = 42.7 bits (99), Expect = 0.001
Identities = 54/237 (22%), Positives = 97/237 (40%), Gaps = 41/237 (17%)
Query: 328 RKKQAKSHFGDKKQLDSKGDCQ-KATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRH-RS 385
++KQ +S G S + + +T S +SS + S G + S S P+ + RH RS
Sbjct: 502 KEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRS 561
Query: 386 SDSDLSPPRRRQRTKSSDSDLSPPR-RSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKE 444
+ R R R+ S + R R + ++ ++ S I+RE++ +
Sbjct: 562 RSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNS----------IERERRRNRS 611
Query: 445 QDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQS 504
+E R +S +R + R R + + D +R L K ++
Sbjct: 612 PSRERRRS-----------RSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEA 660
Query: 505 RQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKK 561
++Q E +K +R I D+D + +E+ERE D K K K+ + +K
Sbjct: 661 KEQ---------ERKKERSRSI-DKDRKKKDKEREREQD-------KRKEKQKREEK 700
Score = 32.0 bits (71), Expect = 1.7
Identities = 53/264 (20%), Positives = 99/264 (37%), Gaps = 21/264 (7%)
Query: 163 SPLRGARHDSDT-SPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHD 221
S L D D + +R ++++ P++ H + R +SSG+S R
Sbjct: 467 SLLEAREADGDVVNEKKRTPNETTSVLEPKK-EHKEKEKQGRSRSGSSSSGSSSSNSRTS 525
Query: 222 SPDP-------SPPRRARHGSSDISSPRRVHNNSPDTS-----RRTLGSSDTQQLR---- 265
S S + SS SSP+R +S S RR+ S +++++
Sbjct: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESN 585
Query: 266 RARHDSPDLAPNVTYSLPR-TKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDI 324
RAR D + S+ R + ++P R ++ ++ + S ++ D
Sbjct: 586 RARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQ 645
Query: 325 SPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRP-RH 383
+ H G+ K+ + K + ++ D D + K+ QD + + +
Sbjct: 646 RGNLSGNSHKHKGEAKEQERKKERSRSIDKD-RKKKDKEREREQDKRKEKQKREEKDFKF 704
Query: 384 RSSDSDLSPPRRRQRTKSSDSDLS 407
S D L R +RT S +S
Sbjct: 705 SSQDDRLKRKRESERTFSRSGSIS 728
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 50.8 bits (120), Expect = 4e-06
Identities = 84/359 (23%), Positives = 134/359 (37%), Gaps = 40/359 (11%)
Query: 201 SPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSD 260
S R P +SG+ RR R S P P + AR SPR + S SR +
Sbjct: 5 SGSRSPDREASGSGGRR-RSSSKSPKPSKSAR-------SPRGRRSRSHSCSRSGDRNGL 56
Query: 261 TQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEY 320
T QL S R +S ++ R+ S+ P S + F S Y
Sbjct: 57 THQLGGLSQGS------------RNQSYRSRSRSRSRERP----SAPRGIPFASASSSVY 100
Query: 321 DPDISPPRKKQAK-SHFGDKKQLDS---KGDCQKATDSDLSSPR-HKQSPGHQDSDSDLS 375
S P DK++ +S K ++ +L +P SP + + DSD
Sbjct: 101 YGSYSRPYGSDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEH 160
Query: 376 PPRNRPRHRSSDSDLSPPRRRQRTKSSDS-DLSPPRRSQPPGKKAAHMYSGAKTGLVLTD 434
P + S + S ++ KSS S + S RR + K+ YS +D
Sbjct: 161 TPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSD----SD 216
Query: 435 IQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELY 494
E + ++D + A +A+ + + R K +K+ K R E + K+S+ + L
Sbjct: 217 SDSE-TDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLE 275
Query: 495 AQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNK 553
W + R + + D + DD+ L+ EG MA ++K K
Sbjct: 276 NPW-----KDRTKAEEPSDLIGPEAPKTLTSQDDKPLNYGHALLPGEGAAMAEYVKAGK 329
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 50.8 bits (120), Expect = 4e-06
Identities = 59/227 (25%), Positives = 92/227 (40%), Gaps = 43/227 (18%)
Query: 11 EYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA------ISTT 64
EY++R S + E GRK++K R K G + D + +S
Sbjct: 113 EYIEREESDGEY-----DEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKY 167
Query: 65 KLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTP 124
KL+++E+EDD DL E + K+ RS +K + + H R +
Sbjct: 168 KLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSR-----------SSHSRSSSR 216
Query: 125 DSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDT------SPPR 178
SSP R S + R + S R+R + + S RG++ S + S PR
Sbjct: 217 SSSPSSSR------SRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR 270
Query: 179 RIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSG-ASPRRVRHDSPD 224
+ + SS +SP R + R + +SSG RR R SP+
Sbjct: 271 KRSYSSSSSSPERNRKRS--------RSRSSSSGDRKKRRTRSRSPE 309
Score = 37.7 bits (86), Expect = 0.032
Identities = 37/134 (27%), Positives = 57/134 (42%), Gaps = 6/134 (4%)
Query: 270 DSPDLAP-NVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPR 328
D DL+ N+ S + K R S S +S S P +S+
Sbjct: 176 DDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS 235
Query: 329 KKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQD-SDSDLSPPRNRPRHRSSD 387
Q++S +++ S+G +++ S R SP + S S SP RNR R RS
Sbjct: 236 SSQSRSRSSSRERSRSRGSKSRSSSR---SHRGSSSPRKRSYSSSSSSPERNRKRSRSRS 292
Query: 388 SDLSPPRRRQRTKS 401
S S R+++RT+S
Sbjct: 293 SS-SGDRKKRRTRS 305
Score = 34.3 bits (77), Expect = 0.35
Identities = 40/201 (19%), Positives = 70/201 (34%), Gaps = 9/201 (4%)
Query: 314 KNSKYEYDPDISPPRKKQAKSHFGDK---KQLDSKGDCQKATDSDLSSPRHKQSPGHQDS 370
+ S EYD + +KK G K+++ K + D D ++K +
Sbjct: 118 EESDGEYD-EFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDED 176
Query: 371 DSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGL 430
D+DLS N DS+ RR R+KS S RS P + S +++
Sbjct: 177 DADLSK-YNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS 235
Query: 431 VLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSER 490
R + + + + + + + + S RKR+ R ++ R
Sbjct: 236 SSQSRSRSSSRERSRSRGSKSRSSSRSHRGS----SSPRKRSYSSSSSSPERNRKRSRSR 291
Query: 491 DELYAQWGKGLAQSRQQQQNV 511
K +SR + V
Sbjct: 292 SSSSGDRKKRRTRSRSPESQV 312
Score = 32.7 bits (73), Expect = 1.0
Identities = 34/138 (24%), Positives = 54/138 (39%), Gaps = 11/138 (7%)
Query: 292 ERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKA 351
E S+K + + S S ++S P S R + ++S Q S+ ++
Sbjct: 190 EEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSR-SRSRSSSSSQSRSRSSSRER 248
Query: 352 TDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRS-SDSDLSPPRRRQRTKSSDSDLSPPR 410
+ S S R S H+ S S PR RS S S SP R R+R++S S +
Sbjct: 249 SRSRGSKSR-SSSRSHRGSSS--------PRKRSYSSSSSSPERNRKRSRSRSSSSGDRK 299
Query: 411 RSQPPGKKAAHMYSGAKT 428
+ + + G T
Sbjct: 300 KRRTRSRSPESQVIGENT 317
Score = 31.6 bits (70), Expect = 2.3
Identities = 34/116 (29%), Positives = 49/116 (42%), Gaps = 7/116 (6%)
Query: 178 RRIRHDSSDTSPPRRARHDSPDPSPPR-RPQHNSSGASPRRVRHDSPDPSPPRRARHGSS 236
RR R S + +R SP S R R + SS +S R R S + S R+R S
Sbjct: 200 RRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERS---RSRGSKS 256
Query: 237 DISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPE 292
SS R H S +R+ SS + R + + + RT+S ++PE
Sbjct: 257 RSSS--RSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRS-RSPE 309
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 50.4 bits (119), Expect = 5e-06
Identities = 70/368 (19%), Positives = 147/368 (39%), Gaps = 54/368 (14%)
Query: 232 RHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAP 291
R SS++++P + ++ P R+ RR +AP + Y L + A
Sbjct: 216 REYSSELNAPSQESDSHP---RKKKKEKKEDIFRRF-----PVAPLIPYPLITKEDINAI 267
Query: 292 ERASSKTSPHWKESGA-----SHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKG 346
E K +E L K K + +I R+++ + ++++ + +
Sbjct: 268 EMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERER 327
Query: 347 DCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSD------SDLSPPRRRQRTK 400
+ ++ + + R ++ +D D R+R R R D SD + R R R K
Sbjct: 328 EREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREK 387
Query: 401 SSDSDLSPPR-------RSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFE 453
S D + R R + ++ + D +R+++E +E E E
Sbjct: 388 SRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLE 447
Query: 454 AEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVED 513
+ + E +++ R +N ++ ++ R+ EK++ER+E ++++ +
Sbjct: 448 RKLREKEAAYQE---RLKNWEIRERKKTREYEKEAEREE-------------ERRREMAK 491
Query: 514 AMKEMQKPLARYIDDED---------LDRMLREQEREGDPMANFIKKNKAKENKNKKVRP 564
K +++ L Y DD D L + LR++E+E M + K ++ + +++R
Sbjct: 492 EAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKE---MEADERDRKREKEELEEIRQ 548
Query: 565 RYSGPAPP 572
R P
Sbjct: 549 RLLAEGHP 556
Score = 43.5 bits (101), Expect = 6e-04
Identities = 48/269 (17%), Positives = 103/269 (38%), Gaps = 44/269 (16%)
Query: 328 RKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSD 387
R+++ + +++ + D + + D R + ++ SD + R+R R +S D
Sbjct: 331 REREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRD 390
Query: 388 SDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQ 447
+ R R+R + + + R + ++ D +R+++E +E
Sbjct: 391 REREREREREREREREREREREREREREREREREREK---------DKKRDREEDEEDAY 441
Query: 448 ETMAFEAEFQYAETVFRD----------KSGRKRNLKLERLEQRRKA------------- 484
E E + + E +++ K R+ + ER E+RR+
Sbjct: 442 ERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLE 501
Query: 485 EKDSERDELYAQWGKGL------------AQSRQQQQNVEDAMKEMQKPLARYIDDEDLD 532
+ D +RD+ G L A R +++ E+ + Q+ LA D D +
Sbjct: 502 DYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAE 561
Query: 533 RMLREQEREGDPMANFIKKNKAKENKNKK 561
EQE E ++ +++E + +K
Sbjct: 562 LQRMEQEAERRRQPQIKQEPESEEEEEEK 590
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 50.4 bits (119), Expect = 5e-06
Identities = 68/324 (20%), Positives = 117/324 (36%), Gaps = 37/324 (11%)
Query: 110 NEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGAR 169
+ + P + D PD + D S + D+ P + D PD
Sbjct: 175 DSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPD-------- 226
Query: 170 HDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPR 229
D+S + DSSD S A DS D S + S A P DS P
Sbjct: 227 ---DSSDDSDVPDDSSDDS---EAPDDSSDDSEAPDDSSDDSEA-PDDSSDDSEAPDDSS 279
Query: 230 RARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSL--PRTKS 287
S D S ++S D S SD + + D D+ + + L P
Sbjct: 280 DDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAE 339
Query: 288 GKAPE-----------RASSKTSPHWKESGASHLSFPKN-SKYEYDPDISPP-RKKQAKS 334
E A++ S H A +N SK DP+ +P +++ +
Sbjct: 340 DLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPT 399
Query: 335 HFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPR 394
++ G + T + + PR +Q+ + + + PPR R ++ ++ P
Sbjct: 400 EEEPAPVVEQSGKRKSKTKTIVEPPRKRQT----KTKNIVEPPRKR---QTKTKNIVEPL 452
Query: 395 RRQRTKSSDSDLSPPRRSQPPGKK 418
R+++ K+ + ++P + + P KK
Sbjct: 453 RKRKAKTKNVSVTPGHKKRGPSKK 476
Score = 33.5 bits (75), Expect = 0.60
Identities = 55/235 (23%), Positives = 81/235 (34%), Gaps = 25/235 (10%)
Query: 143 DRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSP 202
D +D + + D D S D +P D+SD S A D+ D S
Sbjct: 126 DDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPD-----DNSDDS---EAPDDNSDDS- 176
Query: 203 PRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQ 262
P NS + V D+ D S + S D S V ++ D S SSD
Sbjct: 177 -EAPDDNSDDSD---VPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDS 232
Query: 263 QLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDP 322
+ D + AP+ + + +AP+ +S + S S + E
Sbjct: 233 DVPDDSSDDSE-APDDS-----SDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASD 286
Query: 323 DISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPP 377
D S S D DS+ K+ DSD+ + S D+ DL P
Sbjct: 287 DSSDD------SEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVP 335
Score = 31.2 bits (69), Expect = 3.0
Identities = 79/403 (19%), Positives = 133/403 (33%), Gaps = 58/403 (14%)
Query: 170 HDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPR 229
+D D + D+SD S A D+ D S P NS + D +
Sbjct: 128 NDDDNGNDLEVPDDNSDDS---EAPDDNSDDS--EAPDDNSDDSEAPDDNSDDSEAPDDN 182
Query: 230 RARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGK 289
D +S +NS D+S SD + D PD +
Sbjct: 183 SDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPD---------DSSDDSD 233
Query: 290 APERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQ 349
P+ +S + P +S D P S D DS+
Sbjct: 234 VPDDSSDDSEA------------PDDSS----DDSEAPDDSSDDSEAPDDSSDDSEAPDD 277
Query: 350 KATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPP 409
+ DS+ S S DS D P ++ S DSD+ KS DSD+ P
Sbjct: 278 SSDDSEASDDSSDDSEASDDSSDDSEAPDDK----SDDSDVP------EDKSDDSDV--P 325
Query: 410 RRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEA-EFQYAETVFRDKSG 468
+ + G + +D + + Q + +A E E + + S
Sbjct: 326 DDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSD 385
Query: 469 RKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDD 528
+ N ++ RK + E + Q GK ++++ ++ P R
Sbjct: 386 PEANPEV----SERKLPTEEEPAPVVEQSGKRKSKTK----------TIVEPPRKRQTKT 431
Query: 529 EDLDRMLREQEREGDPMANFIKKNKAKENKNKKVRPRYSGPAP 571
+++ R+++ + + ++K KAK KN V P + P
Sbjct: 432 KNIVEPPRKRQTKTKNIVEPLRKRKAK-TKNVSVTPGHKKRGP 473
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 50.4 bits (119), Expect = 5e-06
Identities = 72/389 (18%), Positives = 140/389 (35%), Gaps = 37/389 (9%)
Query: 180 IRHDSSDTSPPRRARHDSPDP-SPPRRPQHNSS--GASPRRVRHDS------PDPSPP-- 228
+R +T P R A + D S PR N G P ++ H + P+ +P
Sbjct: 212 VRMAGDETQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAA 271
Query: 229 --------RRARHGSSDIS---------SPRRVHNNSPDTSRRTLGSSDTQQLRRARHDS 271
+R R S IS S R S +R SS RR R S
Sbjct: 272 AKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQS 331
Query: 272 PDLAPNVTYSLPRTKS---GKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPR 328
+ + S R K K+P + SK+ K SH + E + +
Sbjct: 332 KHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK 391
Query: 329 KKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDS 388
+K + +K+ + + + K D D R K ++ D + + + R +
Sbjct: 392 EKDREKEREREKEREKEKERGKNKDRD--KEREKDREKDKEKDREREREKEHEKDRDKEK 449
Query: 389 DLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQE 448
+ + ++R K ++ R+ + Y+ ++ + +R ++
Sbjct: 450 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSP 509
Query: 449 TMAFEAEFQYAETV---FRDKSGRKRNLKLERLEQRRKAEKD-SERDELYAQWGKGLAQS 504
+ + + + + R+K +KR + + + +RR+ E+ S R + GK +
Sbjct: 510 RTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEK 569
Query: 505 RQQQQNVEDAMKEMQKPLARYIDDEDLDR 533
++ KE +++ +DD+D R
Sbjct: 570 NSTSLKEKEHNKEPDSSVSKEVDDKDAPR 598
Score = 37.0 bits (84), Expect = 0.054
Identities = 43/204 (21%), Positives = 87/204 (42%), Gaps = 53/204 (25%)
Query: 358 SPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGK 417
S H +S S S R++ +HRS + S R++ R RRS+ P K
Sbjct: 308 SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDR-----------RRSKSPHK 356
Query: 418 KAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLER 477
K + K+ R + +++ ++T R+K K +K +
Sbjct: 357 KRSKSRERRKS--------RSRSHSRDKRKDT--------------REKIKEKERVKEKD 394
Query: 478 LEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLRE 537
E+ R+ EK+ E+++ + GK + ++++++ E D++ DR E
Sbjct: 395 REKEREREKEREKEK---ERGKNKDRDKEREKDREK--------------DKEKDR---E 434
Query: 538 QEREGDPMANFIKKNKAKENKNKK 561
+ERE + + K+ + +++K K+
Sbjct: 435 REREKEHEKDRDKEKEKEQDKEKE 458
Score = 36.6 bits (83), Expect = 0.070
Identities = 43/197 (21%), Positives = 69/197 (35%), Gaps = 15/197 (7%)
Query: 116 NRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTS 175
+R R S R R T + K+R D R R + RG D D
Sbjct: 361 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 420
Query: 176 PPR-RIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHG 234
+ R + D R H+ + Q R + +++R
Sbjct: 421 REKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR-- 478
Query: 235 SSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERA 294
+P R +N SRR+ SS ++ RR+R S +P + ++ R KS ++P
Sbjct: 479 -----TPPRSYN----ASRRSRSSSRERRRRRSR--SSSRSPRTSKTIKR-KSSRSPSPR 526
Query: 295 SSKTSPHWKESGASHLS 311
S +E H+S
Sbjct: 527 SRNKKDKKREKERDHIS 543
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,206,115
Number of Sequences: 37866
Number of extensions: 1929358
Number of successful extensions: 14979
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 145
Number of HSP's successfully gapped in prelim test: 1068
Number of HSP's that attempted gapping in prelim test: 10012
Number of HSP's gapped (non-prelim): 4053
length of query: 619
length of database: 18,247,518
effective HSP length: 108
effective length of query: 511
effective length of database: 14,157,990
effective search space: 7234732890
effective search space used: 7234732890
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.