BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapiens] (789 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi... 1556 0.0 gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] 1548 0.0 gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] 1358 0.0 gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi... 1358 0.0 gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi... 1276 0.0 gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] 1276 0.0 gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 1230 0.0 gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 1230 0.0 gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 1202 0.0 gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap... 1201 0.0 gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi... 1201 0.0 gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi... 1200 0.0 gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] 1200 0.0 gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 1199 0.0 gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi... 1196 0.0 gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] 1196 0.0 gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi... 1192 0.0 gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 1192 0.0 gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi... 1187 0.0 gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] 1187 0.0 gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap... 1182 0.0 gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi... 1182 0.0 gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap... 1178 0.0 gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi... 1178 0.0 gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap... 1167 0.0 gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi... 1167 0.0 gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi... 786 0.0 gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap... 778 0.0 gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi... 774 0.0 gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 608 e-174 >gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapiens] Length = 789 Score = 1556 bits (4029), Expect = 0.0 Identities = 789/789 (100%), Positives = 789/789 (100%) Query: 1 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 60 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV Sbjct: 1 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 60 Query: 61 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 120 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD Sbjct: 61 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 120 Query: 121 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL Sbjct: 121 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 360 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 360 Query: 361 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA Sbjct: 361 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480 Query: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT Sbjct: 601 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 660 Query: 661 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP Sbjct: 721 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780 Query: 781 SSTDNVSHK 789 SSTDNVSHK Sbjct: 781 SSTDNVSHK 789 >gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] Length = 937 Score = 1548 bits (4008), Expect = 0.0 Identities = 785/785 (100%), Positives = 785/785 (100%) Query: 1 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 60 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV Sbjct: 1 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 60 Query: 61 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 120 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD Sbjct: 61 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 120 Query: 121 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL Sbjct: 121 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 360 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 360 Query: 361 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA Sbjct: 361 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480 Query: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT Sbjct: 601 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 660 Query: 661 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP Sbjct: 721 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780 Query: 781 SSTDN 785 SSTDN Sbjct: 781 SSTDN 785 >gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] Length = 842 Score = 1358 bits (3515), Expect = 0.0 Identities = 696/777 (89%), Positives = 721/777 (92%) Query: 8 DPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAV 67 DP G+ LLL ++ILA W G GQLHYSVPEEA+HG FVGRIAQDLGLELAELVPRLF+ Sbjct: 8 DPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLD 67 Query: 68 CKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIN 127 K RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEVKDIN Sbjct: 68 SKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127 Query: 128 DNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187 DNPPVFPATQ+NLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ Sbjct: 128 DNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187 Query: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY Sbjct: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247 Query: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH Sbjct: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307 Query: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGT 367 MDFEESRAHKIPVEAVDKGFPPLAGHCT+LVEVVDVNDNAPQLT+ +LS+P+ EDAQ GT Sbjct: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGT 367 Query: 368 VITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 VI LISV D D NGQVTCSLTP VPFKLVST+KNYYSLVLD ALDRESVSAYELVVTA Sbjct: 368 VIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTA 427 Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKN 487 RDGGSPSLWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+N Sbjct: 428 RDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQEN 487 Query: 488 ALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 ALVSYSLVE R+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS Sbjct: 488 ALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 Query: 548 NVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWL 607 NVTLQVFVLDENDNAPALL PR+ GT GAV E+V RSVGAG VV KVRAVDADSGYNAWL Sbjct: 548 NVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWL 607 Query: 608 SYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLV 667 SYELQP A ASIPFRVGLYTGEISTTRALDETDAPR RLLVLVKDHGEP+LTATATVLV Sbjct: 608 SYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLV 667 Query: 668 SLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPS 727 SLVESGQAPK+SSRAS+G GPE LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA Sbjct: 668 SLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMP 727 Query: 728 SEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784 +EG C+ KPTLVCSSAVGSWS+SQQRRQRVCSGEG KTDLMAFSP L ST+ Sbjct: 728 TEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTE 784 >gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1358 bits (3515), Expect = 0.0 Identities = 696/777 (89%), Positives = 721/777 (92%) Query: 8 DPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAV 67 DP G+ LLL ++ILA W G GQLHYSVPEEA+HG FVGRIAQDLGLELAELVPRLF+ Sbjct: 8 DPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLD 67 Query: 68 CKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIN 127 K RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEVKDIN Sbjct: 68 SKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127 Query: 128 DNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187 DNPPVFPATQ+NLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ Sbjct: 128 DNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187 Query: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY Sbjct: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247 Query: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH Sbjct: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307 Query: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGT 367 MDFEESRAHKIPVEAVDKGFPPLAGHCT+LVEVVDVNDNAPQLT+ +LS+P+ EDAQ GT Sbjct: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGT 367 Query: 368 VITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 VI LISV D D NGQVTCSLTP VPFKLVST+KNYYSLVLD ALDRESVSAYELVVTA Sbjct: 368 VIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTA 427 Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKN 487 RDGGSPSLWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+N Sbjct: 428 RDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQEN 487 Query: 488 ALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 ALVSYSLVE R+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS Sbjct: 488 ALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 Query: 548 NVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWL 607 NVTLQVFVLDENDNAPALL PR+ GT GAV E+V RSVGAG VV KVRAVDADSGYNAWL Sbjct: 548 NVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWL 607 Query: 608 SYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLV 667 SYELQP A ASIPFRVGLYTGEISTTRALDETDAPR RLLVLVKDHGEP+LTATATVLV Sbjct: 608 SYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLV 667 Query: 668 SLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPS 727 SLVESGQAPK+SSRAS+G GPE LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA Sbjct: 668 SLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMP 727 Query: 728 SEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784 +EG C+ KPTLVCSSAVGSWS+SQQRRQRVCSGEG KTDLMAFSP L ST+ Sbjct: 728 TEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTE 784 >gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapiens] Length = 798 Score = 1276 bits (3303), Expect = 0.0 Identities = 654/775 (84%), Positives = 695/775 (89%) Query: 12 RHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFR 71 R LLL +++LAAWEAG GQLHYSV EEAKHG FVGRIAQDLGLELAELVPRLFR K R Sbjct: 12 RRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGR 71 Query: 72 GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPP 131 G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIV+RPLQVFHVDVEV+DINDNPP Sbjct: 72 GGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131 Query: 132 VFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191 VFPATQ+NL IAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF L+ P ++ VK Sbjct: 132 VFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKG 191 Query: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251 LGL+LRK LDREE PE+ L+LTATDGGKPELTGTVQLLITVLD NDNAP FDRT+Y V+L Sbjct: 192 LGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRL 251 Query: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311 ENV GTLVI NASDLDEGLNGDI+YSFS+D+SP++KSKFH+DP++G I V G++DFE Sbjct: 252 LENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFE 311 Query: 312 ESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITL 371 ES++++I VE +DKG PL+GHC V+VEV D NDN P L SLSLPI EDA GTVI L Sbjct: 312 ESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIAL 371 Query: 372 ISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431 ISV D+D GVNG VTCSLT VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG Sbjct: 372 ISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431 Query: 432 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVS 491 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NALVS Sbjct: 432 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 491 Query: 492 YSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551 YSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLGSNVTL Sbjct: 492 YSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTL 551 Query: 552 QVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYEL 611 QVFVLDENDNAPALLAPR GGTGGAV ELVP SVG GHVVAKVRAVDADSGYNAWLSYEL Sbjct: 552 QVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYEL 611 Query: 612 QPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVE 671 QP GA IPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEP+LTATATVLVSLVE Sbjct: 612 QPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVE 671 Query: 672 SGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGA 731 SGQAPKASSRA +G GP+ LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +EGA Sbjct: 672 SGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGA 731 Query: 732 CSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNV 786 C+ KPTLVCSSAVGSWS+SQQRR RVCSGEGPPKTDLMAFSPSLP D + Sbjct: 732 CAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQL 786 >gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] Length = 947 Score = 1276 bits (3303), Expect = 0.0 Identities = 654/775 (84%), Positives = 695/775 (89%) Query: 12 RHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFR 71 R LLL +++LAAWEAG GQLHYSV EEAKHG FVGRIAQDLGLELAELVPRLFR K R Sbjct: 12 RRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGR 71 Query: 72 GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPP 131 G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIV+RPLQVFHVDVEV+DINDNPP Sbjct: 72 GGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131 Query: 132 VFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191 VFPATQ+NL IAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF L+ P ++ VK Sbjct: 132 VFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKG 191 Query: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251 LGL+LRK LDREE PE+ L+LTATDGGKPELTGTVQLLITVLD NDNAP FDRT+Y V+L Sbjct: 192 LGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRL 251 Query: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311 ENV GTLVI NASDLDEGLNGDI+YSFS+D+SP++KSKFH+DP++G I V G++DFE Sbjct: 252 LENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFE 311 Query: 312 ESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITL 371 ES++++I VE +DKG PL+GHC V+VEV D NDN P L SLSLPI EDA GTVI L Sbjct: 312 ESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIAL 371 Query: 372 ISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431 ISV D+D GVNG VTCSLT VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG Sbjct: 372 ISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431 Query: 432 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVS 491 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NALVS Sbjct: 432 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 491 Query: 492 YSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551 YSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLGSNVTL Sbjct: 492 YSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTL 551 Query: 552 QVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYEL 611 QVFVLDENDNAPALLAPR GGTGGAV ELVP SVG GHVVAKVRAVDADSGYNAWLSYEL Sbjct: 552 QVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYEL 611 Query: 612 QPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVE 671 QP GA IPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEP+LTATATVLVSLVE Sbjct: 612 QPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVE 671 Query: 672 SGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGA 731 SGQAPKASSRA +G GP+ LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +EGA Sbjct: 672 SGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGA 731 Query: 732 CSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNV 786 C+ KPTLVCSSAVGSWS+SQQRR RVCSGEGPPKTDLMAFSPSLP D + Sbjct: 732 CAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQL 786 >gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1230 bits (3183), Expect = 0.0 Identities = 630/777 (81%), Positives = 685/777 (88%) Query: 8 DPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAV 67 DPG + LLL +++LAA E G GQLHYSV EEAKHG FVGRIAQDLGLELAELVPRLFR Sbjct: 8 DPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 Query: 68 CKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIN 127 K GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHV+VEVKDIN Sbjct: 68 SKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDIN 127 Query: 128 DNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187 DN PVFP +NLFI+ESR SRF LEGASDADIG N+LLTY L EYF LDV +++ Sbjct: 128 DNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDE 187 Query: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247 ++K LGLVL+K L+RE+TP+ +LL+TA DGGKPELTGT QL ITVLD NDNAP F+RT+Y Sbjct: 188 EIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIY 247 Query: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307 V+L EN GTLV+ NA+DLDEG+N DI YSF++D+S DI SKFH+DP++G I+V G+ Sbjct: 248 KVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGN 307 Query: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGT 367 +DFEES++++I VEA DKG PP++ HCTVL+E+VD+NDN P+L + SLSLP+ ED+ T Sbjct: 308 IDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLST 367 Query: 368 VITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 VI LISV DRD GVNGQVTCSLTP VPFKLVSTFKNYYSLVLDS LDRESVSAYELVVTA Sbjct: 368 VIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTA 427 Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKN 487 RDGGSPSLWATASVSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA DADAQ+N Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQEN 487 Query: 488 ALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 ALVSYSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS Sbjct: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 Query: 548 NVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWL 607 NVTLQVFVLDENDNAPALL PRVGG GGAV ELVPRSVGAGHVVAKVRAVDADSGYNAWL Sbjct: 548 NVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWL 607 Query: 608 SYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLV 667 SYELQP GA IPFRVGLYTGEISTTRALDE DAPRHRLLVLVKDHGEPSLTATATVLV Sbjct: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLV 667 Query: 668 SLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPS 727 SLVESGQAPKASS+AS G GPE LVDVNVYLI+AICAVSSLLVLTLLLYTALRCSAP Sbjct: 668 SLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPP 727 Query: 728 SEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784 +EG C KPTLVCSSAVGSWS+SQQR+QRVCSGEG PKTDLMAFSPSLP P S D Sbjct: 728 TEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRD 784 >gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1230 bits (3183), Expect = 0.0 Identities = 630/777 (81%), Positives = 685/777 (88%) Query: 8 DPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAV 67 DPG + LLL +++LAA E G GQLHYSV EEAKHG FVGRIAQDLGLELAELVPRLFR Sbjct: 8 DPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 Query: 68 CKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIN 127 K GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHV+VEVKDIN Sbjct: 68 SKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDIN 127 Query: 128 DNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187 DN PVFP +NLFI+ESR SRF LEGASDADIG N+LLTY L EYF LDV +++ Sbjct: 128 DNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDE 187 Query: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247 ++K LGLVL+K L+RE+TP+ +LL+TA DGGKPELTGT QL ITVLD NDNAP F+RT+Y Sbjct: 188 EIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIY 247 Query: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307 V+L EN GTLV+ NA+DLDEG+N DI YSF++D+S DI SKFH+DP++G I+V G+ Sbjct: 248 KVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGN 307 Query: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGT 367 +DFEES++++I VEA DKG PP++ HCTVL+E+VD+NDN P+L + SLSLP+ ED+ T Sbjct: 308 IDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLST 367 Query: 368 VITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 VI LISV DRD GVNGQVTCSLTP VPFKLVSTFKNYYSLVLDS LDRESVSAYELVVTA Sbjct: 368 VIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTA 427 Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKN 487 RDGGSPSLWATASVSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA DADAQ+N Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQEN 487 Query: 488 ALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 ALVSYSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS Sbjct: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 Query: 548 NVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWL 607 NVTLQVFVLDENDNAPALL PRVGG GGAV ELVPRSVGAGHVVAKVRAVDADSGYNAWL Sbjct: 548 NVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWL 607 Query: 608 SYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLV 667 SYELQP GA IPFRVGLYTGEISTTRALDE DAPRHRLLVLVKDHGEPSLTATATVLV Sbjct: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLV 667 Query: 668 SLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPS 727 SLVESGQAPKASS+AS G GPE LVDVNVYLI+AICAVSSLLVLTLLLYTALRCSAP Sbjct: 668 SLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPP 727 Query: 728 SEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784 +EG C KPTLVCSSAVGSWS+SQQR+QRVCSGEG PKTDLMAFSPSLP P S D Sbjct: 728 TEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRD 784 >gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapiens] Length = 816 Score = 1202 bits (3110), Expect = 0.0 Identities = 617/777 (79%), Positives = 671/777 (86%) Query: 11 GRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKF 70 G LLL ++LA W+AG GQLHYS+PEEAKHG FVGRIAQDLGLELAELVPRLFR K Sbjct: 10 GSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKG 69 Query: 71 RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNP 130 RGDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIV+RPLQVFHV+V VKDINDNP Sbjct: 70 RGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNP 129 Query: 131 PVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVK 190 P F ++ LFI ESR DSRFPLEGASD DIG NA L YRL+PNEYF LDV T+ ++ Sbjct: 130 PRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETN 189 Query: 191 PLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVK 250 L LVLRK LDREET E LL+ ATDGGKPELTGTVQLLI VLD NDNAP FD+++Y V+ Sbjct: 190 FLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVR 249 Query: 251 LPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDF 310 L EN GTLVI NASD DEG+N +I+Y FS+ V D+KSKF ++ +G I V G +D+ Sbjct: 250 LLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDY 309 Query: 311 EESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVIT 370 E+ +++I ++A+DK PL+GHC V+V+++DVNDN P++ +T+L LP+ EDA TVI Sbjct: 310 EDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIA 369 Query: 371 LISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDG 430 LISV DRD G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRESVS YELVVTARDG Sbjct: 370 LISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDG 429 Query: 431 GSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALV 490 GSPSLWATASVSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQ+NALV Sbjct: 430 GSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALV 489 Query: 491 SYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVT 550 SYSLVE RVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVT Sbjct: 490 SYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVT 549 Query: 551 LQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYE 610 LQVFVLDENDNAPALL PRVGGTGGAV ELVPRSVGAGHVVAKVRAVD DSGYNAWLSYE Sbjct: 550 LQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYE 609 Query: 611 LQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLV 670 LQP A IPFRVGLYTGEISTTR+LDET+APRHRLLVLVKDHGEP LTATATVLVSLV Sbjct: 610 LQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLV 669 Query: 671 ESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEG 730 ESGQAPKASSRAS G GPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +E Sbjct: 670 ESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQPTEA 729 Query: 731 ACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNVS 787 C+ KPTL+CSSAVGSWS+SQQRRQRVCSGE PPKTDLMAFSPSLPQGP+STDNVS Sbjct: 730 VCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTDNVS 786 >gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1201 bits (3107), Expect = 0.0 Identities = 615/781 (78%), Positives = 671/781 (85%) Query: 9 PGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVC 68 P R LLL+++ILAAWE G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR Sbjct: 9 PRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 Query: 69 KFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIND 128 K GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHV+V+V+DIND Sbjct: 69 KRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDIND 128 Query: 129 NPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQ 188 NPP+FP +++ + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF LD S +Q Sbjct: 129 NPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQ 188 Query: 189 VKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYT 248 + L LVLRK LDREE E LLLTA+DGGKPELTGTVQLLIT+LD NDNAP F +++Y Sbjct: 189 MSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYK 248 Query: 249 VKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHM 308 V + EN GTLVI NA+D D+G NGDI+YSF V P + F ++P +G I G + Sbjct: 249 VTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKL 308 Query: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTV 368 DFEE + ++I VEAVDKG P+AGHCT+LVEV+DVNDNAP++T+TSLSLPI ED QP + Sbjct: 309 DFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAI 368 Query: 369 ITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428 I LISV DRD G NGQVTC+LTP VPFKLVST+KNYYSLVLDSALDRESVSAYELVVTAR Sbjct: 369 IALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428 Query: 429 DGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNA 488 DGGSPSLWATASVSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NA Sbjct: 429 DGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENA 488 Query: 489 LVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGSN Sbjct: 489 LVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSN 548 Query: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 VTLQVFVLDENDNAPALL P G GG V EL+PRSVGAGHVVAKVRAVDADSGYNAWLS Sbjct: 549 VTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLS 608 Query: 609 YELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVS 668 YELQ A GA IPFRVGLYTGEISTTR LDE DAP HRLLVLVKDHGEP+LTATATVL+S Sbjct: 609 YELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLS 668 Query: 669 LVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSS 728 LVESGQAP+ASSRAS G GPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP + Sbjct: 669 LVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 Query: 729 EGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNVSH 788 EGAC+ KPTLVCSSA GSWS+SQQRR RVCSGEGP KTDLMAFSPSLP S + Sbjct: 729 EGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGTGQ 788 Query: 789 K 789 + Sbjct: 789 R 789 >gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1201 bits (3107), Expect = 0.0 Identities = 615/781 (78%), Positives = 671/781 (85%) Query: 9 PGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVC 68 P R LLL+++ILAAWE G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR Sbjct: 9 PRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 Query: 69 KFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIND 128 K GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHV+V+V+DIND Sbjct: 69 KRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDIND 128 Query: 129 NPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQ 188 NPP+FP +++ + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF LD S +Q Sbjct: 129 NPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQ 188 Query: 189 VKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYT 248 + L LVLRK LDREE E LLLTA+DGGKPELTGTVQLLIT+LD NDNAP F +++Y Sbjct: 189 MSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYK 248 Query: 249 VKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHM 308 V + EN GTLVI NA+D D+G NGDI+YSF V P + F ++P +G I G + Sbjct: 249 VTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKL 308 Query: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTV 368 DFEE + ++I VEAVDKG P+AGHCT+LVEV+DVNDNAP++T+TSLSLPI ED QP + Sbjct: 309 DFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAI 368 Query: 369 ITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428 I LISV DRD G NGQVTC+LTP VPFKLVST+KNYYSLVLDSALDRESVSAYELVVTAR Sbjct: 369 IALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428 Query: 429 DGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNA 488 DGGSPSLWATASVSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NA Sbjct: 429 DGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENA 488 Query: 489 LVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGSN Sbjct: 489 LVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSN 548 Query: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 VTLQVFVLDENDNAPALL P G GG V EL+PRSVGAGHVVAKVRAVDADSGYNAWLS Sbjct: 549 VTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLS 608 Query: 609 YELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVS 668 YELQ A GA IPFRVGLYTGEISTTR LDE DAP HRLLVLVKDHGEP+LTATATVL+S Sbjct: 609 YELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLS 668 Query: 669 LVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSS 728 LVESGQAP+ASSRAS G GPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP + Sbjct: 669 LVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 Query: 729 EGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNVSH 788 EGAC+ KPTLVCSSA GSWS+SQQRR RVCSGEGP KTDLMAFSPSLP S + Sbjct: 729 EGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGTGQ 788 Query: 789 K 789 + Sbjct: 789 R 789 >gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapiens] Length = 803 Score = 1200 bits (3105), Expect = 0.0 Identities = 614/771 (79%), Positives = 672/771 (87%) Query: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 G + LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR K Sbjct: 10 GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69 Query: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 R DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEV+DINDN Sbjct: 70 DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129 Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 PP+FP ++ + I ESR DS FPLEGASDAD+G N++LTY+LS +EYF LDV ++ Sbjct: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189 Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 K +GL+L+K LDREE P +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V Sbjct: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 ++ EN GT VI NASD DEG NG I YSF+S V+ + F +D +G I + G++D Sbjct: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309 Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 FE+ +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 LISV D D G NGQV CSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD Sbjct: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 GGSPSLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVE RVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLAPRVGGTGGAV ELVPRS+GAG VVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669 ELQP A+ A PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LTATATVLVSL Sbjct: 610 ELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729 VESGQAPKASSRAS+G AGPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP +E Sbjct: 670 VESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTE 729 Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780 GAC+ KPTLVCSSAVGSWS+SQQRRQRVCSGEGPPK DLMAFSPSL P Sbjct: 730 GACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 >gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1200 bits (3105), Expect = 0.0 Identities = 614/771 (79%), Positives = 672/771 (87%) Query: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 G + LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR K Sbjct: 10 GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69 Query: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 R DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEV+DINDN Sbjct: 70 DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129 Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 PP+FP ++ + I ESR DS FPLEGASDAD+G N++LTY+LS +EYF LDV ++ Sbjct: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189 Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 K +GL+L+K LDREE P +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V Sbjct: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 ++ EN GT VI NASD DEG NG I YSF+S V+ + F +D +G I + G++D Sbjct: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309 Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 FE+ +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 LISV D D G NGQV CSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD Sbjct: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 GGSPSLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVE RVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLAPRVGGTGGAV ELVPRS+GAG VVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669 ELQP A+ A PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LTATATVLVSL Sbjct: 610 ELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729 VESGQAPKASSRAS+G AGPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP +E Sbjct: 670 VESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTE 729 Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780 GAC+ KPTLVCSSAVGSWS+SQQRRQRVCSGEGPPK DLMAFSPSL P Sbjct: 730 GACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 >gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] Length = 936 Score = 1199 bits (3102), Expect = 0.0 Identities = 615/775 (79%), Positives = 669/775 (86%) Query: 11 GRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKF 70 G LLL ++LA W+AG GQLHYS+PEEAKHG FVGRIAQDLGLELAELVPRLFR K Sbjct: 10 GSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKG 69 Query: 71 RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNP 130 RGDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIV+RPLQVFHV+V VKDINDNP Sbjct: 70 RGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNP 129 Query: 131 PVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVK 190 P F ++ LFI ESR DSRFPLEGASD DIG NA L YRL+PNEYF LDV T+ ++ Sbjct: 130 PRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETN 189 Query: 191 PLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVK 250 L LVLRK LDREET E LL+ ATDGGKPELTGTVQLLI VLD NDNAP FD+++Y V+ Sbjct: 190 FLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVR 249 Query: 251 LPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDF 310 L EN GTLVI NASD DEG+N +I+Y FS+ V D+KSKF ++ +G I V G +D+ Sbjct: 250 LLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDY 309 Query: 311 EESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVIT 370 E+ +++I ++A+DK PL+GHC V+V+++DVNDN P++ +T+L LP+ EDA TVI Sbjct: 310 EDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIA 369 Query: 371 LISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDG 430 LISV DRD G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRESVS YELVVTARDG Sbjct: 370 LISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDG 429 Query: 431 GSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALV 490 GSPSLWATASVSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQ+NALV Sbjct: 430 GSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALV 489 Query: 491 SYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVT 550 SYSLVE RVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVT Sbjct: 490 SYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVT 549 Query: 551 LQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYE 610 LQVFVLDENDNAPALL PRVGGTGGAV ELVPRSVGAGHVVAKVRAVD DSGYNAWLSYE Sbjct: 550 LQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYE 609 Query: 611 LQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLV 670 LQP A IPFRVGLYTGEISTTR+LDET+APRHRLLVLVKDHGEP LTATATVLVSLV Sbjct: 610 LQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLV 669 Query: 671 ESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEG 730 ESGQAPKASSRAS G GPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +E Sbjct: 670 ESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQPTEA 729 Query: 731 ACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDN 785 C+ KPTL+CSSAVGSWS+SQQRRQRVCSGE PPKTDLMAFSPSLPQGP+STDN Sbjct: 730 VCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTDN 784 >gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1196 bits (3094), Expect = 0.0 Identities = 613/767 (79%), Positives = 671/767 (87%) Query: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 G R LLL++++LAAWE G GQLHYS+PEEAKHG FVGR+AQDLGLELAELVPRLFR K Sbjct: 10 GARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELVPRLFRVASK 69 Query: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 DLLEVNLQNGILFVNSRIDREELC SAECSIHLE+I +RPLQVFHV+V+VKDINDN Sbjct: 70 THRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVEVKVKDINDN 129 Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 PPVF ++ +FI ESR L+SRFP+EGA+DADIG NALLTY LSP++YF LDV S++ Sbjct: 130 PPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEASDELS 189 Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 K L L LRK LDREETPELHLLLTATDGGKPEL GTV+LLITVLD NDNAP+FD+ +Y V Sbjct: 190 KSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRV 249 Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 L E + GTLV NASD DEG+NG++++SF S +S DI+ KF +D SG I +I +D Sbjct: 250 HLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRLIDKLD 309 Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 +EE+++++I V+AVDKG PP++ HC VLV+V+DVNDNAP+L +TSL LPI EDA TVI Sbjct: 310 YEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDAPLSTVI 369 Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 LI+V DRD G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRES+S YELVVTARD Sbjct: 370 ALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSVYELVVTARD 429 Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 GGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVE RVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLAPRVGGT GAV ELVPR VGAGHVVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669 ELQP A GA IPFRVGLYTGEISTTR LDE D R+RLLVLVKDHGEP+LTATATVLVSL Sbjct: 610 ELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALTATATVLVSL 669 Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729 VESGQAPKASSRAS+G+AGPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCS P +E Sbjct: 670 VESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSVPPTE 729 Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSL 776 GA KPTLVCSSA+GSWS SQQRRQRVCS EGPPKTDLMAFSP L Sbjct: 730 GAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGL 776 >gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1196 bits (3094), Expect = 0.0 Identities = 613/767 (79%), Positives = 671/767 (87%) Query: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 G R LLL++++LAAWE G GQLHYS+PEEAKHG FVGR+AQDLGLELAELVPRLFR K Sbjct: 10 GARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELVPRLFRVASK 69 Query: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 DLLEVNLQNGILFVNSRIDREELC SAECSIHLE+I +RPLQVFHV+V+VKDINDN Sbjct: 70 THRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVEVKVKDINDN 129 Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 PPVF ++ +FI ESR L+SRFP+EGA+DADIG NALLTY LSP++YF LDV S++ Sbjct: 130 PPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEASDELS 189 Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 K L L LRK LDREETPELHLLLTATDGGKPEL GTV+LLITVLD NDNAP+FD+ +Y V Sbjct: 190 KSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRV 249 Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 L E + GTLV NASD DEG+NG++++SF S +S DI+ KF +D SG I +I +D Sbjct: 250 HLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRLIDKLD 309 Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 +EE+++++I V+AVDKG PP++ HC VLV+V+DVNDNAP+L +TSL LPI EDA TVI Sbjct: 310 YEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDAPLSTVI 369 Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 LI+V DRD G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRES+S YELVVTARD Sbjct: 370 ALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSVYELVVTARD 429 Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 GGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVE RVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLAPRVGGT GAV ELVPR VGAGHVVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669 ELQP A GA IPFRVGLYTGEISTTR LDE D R+RLLVLVKDHGEP+LTATATVLVSL Sbjct: 610 ELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALTATATVLVSL 669 Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729 VESGQAPKASSRAS+G+AGPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCS P +E Sbjct: 670 VESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSVPPTE 729 Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSL 776 GA KPTLVCSSA+GSWS SQQRRQRVCS EGPPKTDLMAFSP L Sbjct: 730 GAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGL 776 >gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapiens] Length = 814 Score = 1192 bits (3084), Expect = 0.0 Identities = 609/775 (78%), Positives = 663/775 (85%) Query: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 G LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR K Sbjct: 10 GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 Query: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEVKD+NDN Sbjct: 70 RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129 Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 PPVF + LF++ESR DSRFPLEGASDAD+G N++LTYRLS ++YF LDV + N + Sbjct: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189 Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 K + LVLRK LDRE+ P HL LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V Sbjct: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 ++ EN GT VI NASD DEG NG I YSF+S V + F +D +G I + G++D Sbjct: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309 Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 FE+ +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 LISV D D G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429 Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 GGSPSLWATAS+SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVE RVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALL PRVGGTGGA +LVPRSVGAGHVVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669 ELQP A+ IPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LTATATVLVSL Sbjct: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729 VESGQAPKASSR S G+ GPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +E Sbjct: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729 Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784 G C KPTLVCSSAVGSWS+SQQ+ QRVCSGEGPPKTDLMAFSP LP S D Sbjct: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVD 784 >gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1192 bits (3084), Expect = 0.0 Identities = 609/775 (78%), Positives = 663/775 (85%) Query: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 G LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR K Sbjct: 10 GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 Query: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEVKD+NDN Sbjct: 70 RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129 Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 PPVF + LF++ESR DSRFPLEGASDAD+G N++LTYRLS ++YF LDV + N + Sbjct: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189 Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 K + LVLRK LDRE+ P HL LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V Sbjct: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 ++ EN GT VI NASD DEG NG I YSF+S V + F +D +G I + G++D Sbjct: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309 Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 FE+ +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 LISV D D G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429 Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 GGSPSLWATAS+SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVE RVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALL PRVGGTGGA +LVPRSVGAGHVVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669 ELQP A+ IPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LTATATVLVSL Sbjct: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729 VESGQAPKASSR S G+ GPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +E Sbjct: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729 Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784 G C KPTLVCSSAVGSWS+SQQ+ QRVCSGEGPPKTDLMAFSP LP S D Sbjct: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVD 784 >gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1187 bits (3070), Expect = 0.0 Identities = 606/770 (78%), Positives = 669/770 (86%) Query: 15 LLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGDL 74 LL +++LAAWE G GQL YSVPEEAKHG FVGRIAQDLGLEL ELVPRLFR K GDL Sbjct: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 Query: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVFP 134 LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIV+RPLQVFHV+VEVKDINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 Query: 135 ATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194 T + + ESR LDSRFPLEGASDADIG NALL+Y+LS +E+FFLD+ +++ + L L Sbjct: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 Query: 195 VLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPEN 254 VL K LDREET E++LLL ATDGGKPELTGTVQ+LI VLD NDN P F +++Y VKL EN Sbjct: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 Query: 255 VSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESR 314 + GTLV+ NASD DEG N +I+YS SDVS I++KF +DP+SG I G +D+EE++ Sbjct: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 Query: 315 AHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISV 374 +++I V A DKG P ++GHC + +++VD+NDN P++++TSLSLPI E+A GTVI LI+V Sbjct: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 Query: 375 FDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 DRD G NG VTCSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS Sbjct: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSL 494 LWAT SVS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NALVSYSL Sbjct: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 Query: 495 VELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554 VE RVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554 Query: 555 VLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPV 614 VLDENDNAPALLAPR G GAV ELVP SVGAGHVVAKVRAVDADSGYNAWLSYELQ Sbjct: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614 Query: 615 AAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQ 674 A IPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATVLVSLVESGQ Sbjct: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 Query: 675 APKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGACSL 734 APKASSRA +G AG E LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS P +EGA + Sbjct: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734 Query: 735 VKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784 KPTLVCSSAVGSWS+SQQRRQRVCSGE PPKTDLMAFSPSL QGP S + Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAE 784 >gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1187 bits (3070), Expect = 0.0 Identities = 606/770 (78%), Positives = 669/770 (86%) Query: 15 LLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGDL 74 LL +++LAAWE G GQL YSVPEEAKHG FVGRIAQDLGLEL ELVPRLFR K GDL Sbjct: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 Query: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVFP 134 LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIV+RPLQVFHV+VEVKDINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 Query: 135 ATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194 T + + ESR LDSRFPLEGASDADIG NALL+Y+LS +E+FFLD+ +++ + L L Sbjct: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 Query: 195 VLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPEN 254 VL K LDREET E++LLL ATDGGKPELTGTVQ+LI VLD NDN P F +++Y VKL EN Sbjct: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 Query: 255 VSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESR 314 + GTLV+ NASD DEG N +I+YS SDVS I++KF +DP+SG I G +D+EE++ Sbjct: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 Query: 315 AHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISV 374 +++I V A DKG P ++GHC + +++VD+NDN P++++TSLSLPI E+A GTVI LI+V Sbjct: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 Query: 375 FDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 DRD G NG VTCSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS Sbjct: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSL 494 LWAT SVS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NALVSYSL Sbjct: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 Query: 495 VELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554 VE RVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554 Query: 555 VLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPV 614 VLDENDNAPALLAPR G GAV ELVP SVGAGHVVAKVRAVDADSGYNAWLSYELQ Sbjct: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614 Query: 615 AAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQ 674 A IPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATVLVSLVESGQ Sbjct: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 Query: 675 APKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGACSL 734 APKASSRA +G AG E LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS P +EGA + Sbjct: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734 Query: 735 VKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784 KPTLVCSSAVGSWS+SQQRRQRVCSGE PPKTDLMAFSPSL QGP S + Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAE 784 >gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sapiens] Length = 810 Score = 1182 bits (3059), Expect = 0.0 Identities = 607/770 (78%), Positives = 666/770 (86%), Gaps = 1/770 (0%) Query: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 G L L++++L WE G GQLHYSV EEAKHG FVGRIAQDLGLELAELV RLFR K Sbjct: 10 GTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVASK 69 Query: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 GDLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIV+RPLQVFHV+VEVKDINDN Sbjct: 70 THGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDINDN 129 Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 PPVF ++ L IAES+ DSRFPLEGASDADI ENALLTYRLS NEYF LD PT+ +Q+ Sbjct: 130 PPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQI 189 Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 K L L+L+K LDRE+TPEL+LLLTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y V Sbjct: 190 KRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYKV 249 Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 L EN + TLV+ NA+D DEG+NG++ YS S + P+ + F +D +G + V G +D Sbjct: 250 SLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTLD 308 Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 +EE++ +KI V+A DKG PP+AGHCTV VE++D NDN+P++ +TSLSLP+ EDAQP TVI Sbjct: 309 YEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTVI 368 Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 LISV DRD GVNGQVTCSLTP VPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTARD Sbjct: 369 ALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTARD 428 Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 GGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 429 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 488 Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVE R+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SNV Sbjct: 489 VSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSNV 548 Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLA + G GGAV +LVPRSVGAGHVVAKVRAVDADSGYNAWLSY Sbjct: 549 TLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 608 Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669 ELQP A G+ IPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATVLVSL Sbjct: 609 ELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 668 Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729 VESGQAPKASSR G A PE LVDVNVYLIIAIC VSSLLVLTLLLYTAL SA +E Sbjct: 669 VESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPTE 728 Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQG 779 GAC+ KPTLVCS AVGSWS+SQQRRQRVCS EGPPKTDLMAFSPSLP G Sbjct: 729 GACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLG 778 >gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapiens] Length = 949 Score = 1182 bits (3059), Expect = 0.0 Identities = 607/770 (78%), Positives = 666/770 (86%), Gaps = 1/770 (0%) Query: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 G L L++++L WE G GQLHYSV EEAKHG FVGRIAQDLGLELAELV RLFR K Sbjct: 10 GTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVASK 69 Query: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 GDLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIV+RPLQVFHV+VEVKDINDN Sbjct: 70 THGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDINDN 129 Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 PPVF ++ L IAES+ DSRFPLEGASDADI ENALLTYRLS NEYF LD PT+ +Q+ Sbjct: 130 PPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQI 189 Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 K L L+L+K LDRE+TPEL+LLLTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y V Sbjct: 190 KRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYKV 249 Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 L EN + TLV+ NA+D DEG+NG++ YS S + P+ + F +D +G + V G +D Sbjct: 250 SLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTLD 308 Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 +EE++ +KI V+A DKG PP+AGHCTV VE++D NDN+P++ +TSLSLP+ EDAQP TVI Sbjct: 309 YEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTVI 368 Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 LISV DRD GVNGQVTCSLTP VPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTARD Sbjct: 369 ALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTARD 428 Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 GGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 429 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 488 Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVE R+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SNV Sbjct: 489 VSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSNV 548 Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLA + G GGAV +LVPRSVGAGHVVAKVRAVDADSGYNAWLSY Sbjct: 549 TLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 608 Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669 ELQP A G+ IPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATVLVSL Sbjct: 609 ELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 668 Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729 VESGQAPKASSR G A PE LVDVNVYLIIAIC VSSLLVLTLLLYTAL SA +E Sbjct: 669 VESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPTE 728 Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQG 779 GAC+ KPTLVCS AVGSWS+SQQRRQRVCS EGPPKTDLMAFSPSLP G Sbjct: 729 GACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLG 778 >gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sapiens] Length = 844 Score = 1178 bits (3047), Expect = 0.0 Identities = 614/771 (79%), Positives = 662/771 (85%), Gaps = 1/771 (0%) Query: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 G + LLL +++LAAWE G GQLHYSV EEA+HG FVGRIAQDLGLELAELV RLFR K Sbjct: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68 Query: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 GDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIV+RPLQVFHVDVEVKDINDN Sbjct: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128 Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 PP F T++ L I ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF LD+ + Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188 Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 K LVLRKLLDREE P+L LLLTATDGGKPE TG+V LLI VLD NDNAP+FDR +Y V Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248 Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 K+ EN TLVI NASD DEG+N +++YSFSS V P I+ KF ++ +G I V +D Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308 Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 FE+S ++I V+ DKG PP+ GHCTVLVE++D NDN+P++ +TSLSLP+ EDAQ GTVI Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368 Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 LISV D D G NGQVTCSLTP VPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428 Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 GGSP LWATASVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488 Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVE R+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+ Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548 Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLA G GGAV ELV RSV AGHVVAKVRAVDADSGYNAWLSY Sbjct: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608 Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669 ELQ A GA IPFRVGLYTGEISTTRALDETD+PR RLLVLVKDHGEPSLTATATVLVSL Sbjct: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668 Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729 VE QAPKASSRAS+G+A PE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +E Sbjct: 669 VEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727 Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780 GAC VKPTLVCSSAVGSWS+SQQRRQRVCSGEG PK DLMAFSPSLP P Sbjct: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCP 778 >gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1178 bits (3047), Expect = 0.0 Identities = 614/771 (79%), Positives = 662/771 (85%), Gaps = 1/771 (0%) Query: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 G + LLL +++LAAWE G GQLHYSV EEA+HG FVGRIAQDLGLELAELV RLFR K Sbjct: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68 Query: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 GDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIV+RPLQVFHVDVEVKDINDN Sbjct: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128 Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 PP F T++ L I ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF LD+ + Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188 Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 K LVLRKLLDREE P+L LLLTATDGGKPE TG+V LLI VLD NDNAP+FDR +Y V Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248 Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 K+ EN TLVI NASD DEG+N +++YSFSS V P I+ KF ++ +G I V +D Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308 Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 FE+S ++I V+ DKG PP+ GHCTVLVE++D NDN+P++ +TSLSLP+ EDAQ GTVI Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368 Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 LISV D D G NGQVTCSLTP VPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428 Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 GGSP LWATASVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488 Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVE R+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+ Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548 Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLA G GGAV ELV RSV AGHVVAKVRAVDADSGYNAWLSY Sbjct: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608 Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669 ELQ A GA IPFRVGLYTGEISTTRALDETD+PR RLLVLVKDHGEPSLTATATVLVSL Sbjct: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668 Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729 VE QAPKASSRAS+G+A PE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +E Sbjct: 669 VEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727 Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780 GAC VKPTLVCSSAVGSWS+SQQRRQRVCSGEG PK DLMAFSPSLP P Sbjct: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCP 778 >gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sapiens] Length = 792 Score = 1167 bits (3020), Expect = 0.0 Identities = 606/776 (78%), Positives = 654/776 (84%), Gaps = 2/776 (0%) Query: 1 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 60 ++ P G PG + LLL +++LAAWE G GQLHYSV EEAKHG FVGRIAQDLGLELAELV Sbjct: 3 IIGPRG--PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 120 PRLFR K GDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIV+RPLQVFHVD Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 VEVKDINDNPPVF ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L Sbjct: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 + T + LVLRKLLDRE+TP+L+LLL DGGKPELTG+VQ+ ITVLD NDN P Sbjct: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 FD+ Y V L ENV T VI NASD DEGLNG+I Y + K F ++P +G Sbjct: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 360 I + G +DFEE+ A++I V A+DKG P +AGH VLVEV+DVNDN P++ +TSLSLP+ Sbjct: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360 Query: 361 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDAQ GTVI LISV DRD G NGQV CSLTP VPFKLVST+KNYYSLVLDSALDRESVSA Sbjct: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 Query: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQKNALVSYSLVE RVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLA G GGAV ELVPRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQP A GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 720 +TATVLVSLVE+GQAPK SSRAS+G PE LVD+NVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSL 776 LRCSAP + C+ KPTLVCSSAVGSWS+SQQRRQRVCS E PPKTDLMAFSPSL Sbjct: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 >gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapiens] Length = 941 Score = 1167 bits (3020), Expect = 0.0 Identities = 606/776 (78%), Positives = 654/776 (84%), Gaps = 2/776 (0%) Query: 1 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 60 ++ P G PG + LLL +++LAAWE G GQLHYSV EEAKHG FVGRIAQDLGLELAELV Sbjct: 3 IIGPRG--PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 120 PRLFR K GDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIV+RPLQVFHVD Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 VEVKDINDNPPVF ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L Sbjct: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 + T + LVLRKLLDRE+TP+L+LLL DGGKPELTG+VQ+ ITVLD NDN P Sbjct: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 FD+ Y V L ENV T VI NASD DEGLNG+I Y + K F ++P +G Sbjct: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 360 I + G +DFEE+ A++I V A+DKG P +AGH VLVEV+DVNDN P++ +TSLSLP+ Sbjct: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360 Query: 361 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDAQ GTVI LISV DRD G NGQV CSLTP VPFKLVST+KNYYSLVLDSALDRESVSA Sbjct: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 Query: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQKNALVSYSLVE RVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLA G GGAV ELVPRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQP A GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 720 +TATVLVSLVE+GQAPK SSRAS+G PE LVD+NVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSL 776 LRCSAP + C+ KPTLVCSSAVGSWS+SQQRRQRVCS E PPKTDLMAFSPSL Sbjct: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 >gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapiens] Length = 686 Score = 786 bits (2029), Expect = 0.0 Identities = 398/525 (75%), Positives = 450/525 (85%) Query: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 G R LLL++++LAAWE G GQLHYS+PEEAKHG FVGR+AQDLGLELAELVPRLFR K Sbjct: 10 GARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELVPRLFRVASK 69 Query: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 DLLEVNLQNGILFVNSRIDREELC SAECSIHLE+I +RPLQVFHV+V+VKDINDN Sbjct: 70 THRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVEVKVKDINDN 129 Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 PPVF ++ +FI ESR L+SRFP+EGA+DADIG NALLTY LSP++YF LDV S++ Sbjct: 130 PPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEASDELS 189 Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 K L L LRK LDREETPELHLLLTATDGGKPEL GTV+LLITVLD NDNAP+FD+ +Y V Sbjct: 190 KSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRV 249 Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 L E + GTLV NASD DEG+NG++++SF S +S DI+ KF +D SG I +I +D Sbjct: 250 HLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRLIDKLD 309 Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 +EE+++++I V+AVDKG PP++ HC VLV+V+DVNDNAP+L +TSL LPI EDA TVI Sbjct: 310 YEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDAPLSTVI 369 Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 LI+V DRD G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRES+S YELVVTARD Sbjct: 370 ALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSVYELVVTARD 429 Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 GGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534 VSYSLVE RVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQ Sbjct: 490 VSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534 Score = 151 bits (381), Expect = 3e-36 Identities = 133/431 (30%), Positives = 202/431 (46%), Gaps = 33/431 (7%) Query: 194 LVLRKLLDREETPE------LHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247 L + +DREE + +HL L A +P V+ + V D NDN PVF Sbjct: 84 LFVNSRIDREELCQWSAECSIHLELIAD---RPLQVFHVE--VKVKDINDNPPVFRGREQ 138 Query: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSD--VSPDIKSKFHMDPLSGAI--T 303 + +PE+ + + A+D D G N + Y+ S S D+++ D LS ++ Sbjct: 139 IIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEAS---DELSKSLWLE 195 Query: 304 VIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDA 363 + ++D EE+ + + A D G P L G +L+ V+DVNDNAP + + E Sbjct: 196 LRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRVHLLETT 255 Query: 364 QPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYS---LVLDSALDRESVSA 420 GT++T ++ D D GVNG+V S + + FK S + L LD E + Sbjct: 256 ANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRLIDKLDYEETKS 315 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480 YE+ V A D GSP + V V+V DVNDNAP A + ++E+ P I ++ Sbjct: 316 YEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDAPLSTVIALITVS 375 Query: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 D D+ N V+ SL+ V + +S++ + ++ + LD E L + + V+ARD Sbjct: 376 DRDSGANGQVTCSLMP-HVPFKLVSTFKNYYS----LVLDSALDRESLSVYELVVTARDG 430 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600 G P L + + V V D NDNAPA P V + G + V A DAD Sbjct: 431 GSPSLWATARVSVEVADVNDNAPAFAQPE-------YTVFVKENNPPGCHIFTVSARDAD 483 Query: 601 SGYNAWLSYEL 611 + NA +SY L Sbjct: 484 AQENALVSYSL 494 Score = 148 bits (374), Expect = 2e-35 Identities = 116/343 (33%), Positives = 159/343 (46%), Gaps = 21/343 (6%) Query: 336 VLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPF 395 V V+V D+NDN P + IPE + + D D G N +T +L+P F Sbjct: 119 VEVKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYF 178 Query: 396 KLVSTFKNYYS----LVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDN 451 L + S L L LDRE L++TA DGG P L T + + V DVNDN Sbjct: 179 SLDVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDN 238 Query: 452 APAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSLVELRVGERALSSYVSVH 511 AP F Q Y V + E G + T++A DAD N V +S R + V Sbjct: 239 APLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGI--SRDIQEKFKVD 296 Query: 512 AESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVG 571 + SG++ + LD+EE + + QV A D G PP+ ++ + V VLD NDNAP L V Sbjct: 297 SSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPEL---AVT 353 Query: 572 GTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPVAAGASIPFR-VGLYTGE 630 +RE P S V+A + D DSG N ++ L P +PF+ V + Sbjct: 354 SLYLPIREDAPLST----VIALITVSDRDSGANGQVTCSLMP-----HVPFKLVSTFKNY 404 Query: 631 ISTT--RALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVE 671 S ALD + L+V +D G PSL ATA V V + + Sbjct: 405 YSLVLDSALDRESLSVYELVVTARDGGSPSLWATARVSVEVAD 447 >gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sapiens] Length = 685 Score = 778 bits (2008), Expect = 0.0 Identities = 401/525 (76%), Positives = 443/525 (84%) Query: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 G + LLL +++LAAWE G GQLHYSV EEA+HG FVGRIAQDLGLELAELV RLFR K Sbjct: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68 Query: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 GDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIV+RPLQVFHVDVEVKDINDN Sbjct: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128 Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 PP F T++ L I ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF LD+ + Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188 Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 K LVLRKLLDREE P+L LLLTATDGGKPE TG+V LLI VLD NDNAP+FDR +Y V Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248 Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 K+ EN TLVI NASD DEG+N +++YSFSS V P I+ KF ++ +G I V +D Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308 Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 FE+S ++I V+ DKG PP+ GHCTVLVE++D NDN+P++ +TSLSLP+ EDAQ GTVI Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368 Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 LISV D D G NGQVTCSLTP VPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428 Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 GGSP LWATASVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488 Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534 VSYSLVE R+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQ Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533 Score = 143 bits (361), Expect = 5e-34 Identities = 109/373 (29%), Positives = 167/373 (44%), Gaps = 21/373 (5%) Query: 338 VEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKL 397 VEV D+NDN P+ ++T L IPE + L D D G N +T L+P F L Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179 Query: 398 VSTFKN----YYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAP 453 K + LVL LDRE +L++TA DGG P + S+ + V D NDNAP Sbjct: 180 DIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAP 239 Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSLVELRVGERALSSYVSVHAE 513 F +P Y V + EN + ++A D+D N + YS L + ++ Sbjct: 240 IFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLV--PPTIRRKFWINER 297 Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGT 573 +G++ +D E+ + V D G PP+ + T+ V +LDENDN+P ++ + Sbjct: 298 TGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLP 357 Query: 574 GGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPVAAGASIPFR-VGLYTGEIS 632 V G V+A + D DSG N ++ L P +PF+ V Y S Sbjct: 358 -------VKEDAQVGTVIALISVSDHDSGANGQVTCSLTP-----HVPFKLVSTYKNYYS 405 Query: 633 TT--RALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSRASLGIAGPE 690 ALD + L+V +D G P L ATA+V V + + A +++ + E Sbjct: 406 LVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKE 465 Query: 691 TELVDVNVYLIIA 703 +++ + A Sbjct: 466 NNPPGCHIFTVSA 478 Score = 136 bits (343), Expect = 7e-32 Identities = 113/387 (29%), Positives = 179/387 (46%), Gaps = 18/387 (4%) Query: 230 ITVLDNNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSD--VSP 287 + V D NDN P F T + +PE+ + + ASD D G N + Y S + Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179 Query: 288 DIKSKFHMDPLSGAITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNA 347 DI +K D + + +D EE+ K+ + A D G P G ++L+ V+D NDNA Sbjct: 180 DIINKKDKDKFP-VLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNA 238 Query: 348 PQLTLTSLSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTF---KNY 404 P + + E+ T++ ++ D D G+N ++ S + VP + F + Sbjct: 239 PIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERT 298 Query: 405 YSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFV 464 + ++ A+D E + YE+ V D G+P + +V VE+ D NDN+P ++ V Sbjct: 299 GEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPV 358 Query: 465 KENNPPGCHIFTVSAGDADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLD 524 KE+ G I +S D D+ N V+ SL V + +S+Y + ++ + LD Sbjct: 359 KEDAQVGTVIALISVSDHDSGANGQVTCSLTP-HVPFKLVSTYKNYYS----LVLDSALD 413 Query: 525 HEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRS 584 E + + V+ARD G PPL + ++ V V D NDNAPA V + Sbjct: 414 RERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEYTVFVKEN 466 Query: 585 VGAGHVVAKVRAVDADSGYNAWLSYEL 611 G + V A DAD+ NA +SY L Sbjct: 467 NPPGCHIFTVSAWDADAQENALVSYSL 493 Score = 88.2 bits (217), Expect = 3e-17 Identities = 81/271 (29%), Positives = 115/271 (42%), Gaps = 17/271 (6%) Query: 441 VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSLVELRVG 500 V VEV D+NDN P F+ E + + E+ A DAD +NAL++Y L Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177 Query: 501 ERALSSYVSVHAESGKVYALQPL-DHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDEN 559 L + V L+ L D EE L+ ++A D G P +V+L + VLD N Sbjct: 178 --VLDIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDAN 235 Query: 560 DNAPALLAPRVGGTGGAVRELVPRSVGAGH-VVAKVRAVDADSGYNAWLSYELQP-VAAG 617 DNAP P V E+ +V ++ A D+D G N + Y V Sbjct: 236 DNAPIFDRP--------VYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPT 287 Query: 618 ASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPK 677 F + TGEI A+D D+ + + V V D G P + TVLV L++ Sbjct: 288 IRRKFWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSP 347 Query: 678 ASSRASLGIAGPETELVDVNVYLIIAICAVS 708 SL + E D V +IA+ +VS Sbjct: 348 EVIVTSLSLPVKE----DAQVGTVIALISVS 374 >gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapiens] Length = 686 Score = 774 bits (1999), Expect = 0.0 Identities = 394/525 (75%), Positives = 444/525 (84%) Query: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 G + LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR K Sbjct: 10 GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69 Query: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 R DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEV+DINDN Sbjct: 70 DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129 Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 PP+FP ++ + I ESR DS FPLEGASDAD+G N++LTY+LS +EYF LDV ++ Sbjct: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189 Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 K +GL+L+K LDREE P +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V Sbjct: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 ++ EN GT VI NASD DEG NG I YSF+S V+ + F +D +G I + G++D Sbjct: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309 Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 FE+ +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 LISV D D G NGQV CSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD Sbjct: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 GGSPSLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534 VSYSLVE RVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQ Sbjct: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534 Score = 157 bits (396), Expect = 5e-38 Identities = 116/373 (31%), Positives = 170/373 (45%), Gaps = 21/373 (5%) Query: 338 VEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPF-- 395 VEV D+NDN P + + I E P +V L D D G N +T L+ F Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 396 --KLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAP 453 K+ S L+L +LDRE A+ L +TA DGG P L T + V V DVNDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSLVELRVGERALSSYVSVHAE 513 F Q EY V + EN G + ++A D D N +SYS L + + S+ Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAA--MVIDHFSIDRN 298 Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGT 573 +G++ LD E+ L + + A D G PP+ + T+ V +LD+NDN P + + Sbjct: 299 TGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEI---ALTSL 355 Query: 574 GGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPVAAGASIPFR-VGLYTGEIS 632 VRE G V+A + D DSG N ++ L P +PF+ V + S Sbjct: 356 SLPVRE----DAQFGTVIALISVNDLDSGANGQVNCSLTP-----HVPFKLVSTFKNYYS 406 Query: 633 TT--RALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSRASLGIAGPE 690 ALD + L+V +D G PSL ATA++ V + + A ++ + E Sbjct: 407 LVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKE 466 Query: 691 TELVDVNVYLIIA 703 +++ + A Sbjct: 467 NNPPGCHIFTVSA 479 Score = 155 bits (391), Expect = 2e-37 Identities = 119/386 (30%), Positives = 181/386 (46%), Gaps = 16/386 (4%) Query: 230 ITVLDNNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDI 289 + V D NDN P+F V + E+ ++ ASD D G N + Y SS + Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 290 KSKFHMDPLSG-AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAP 348 K + D + + +D EE+ AH + + A D G P L G +LV V+DVNDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 349 QLTLTSLSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTF---KNYY 405 + + I E+A GT + ++ DRD G NG ++ S V ++ F +N Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 Query: 406 SLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVK 465 +V+ LD E + Y++++ A D G P + +V V + D NDN P A ++ V+ Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 466 ENNPPGCHIFTVSAGDADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDH 525 E+ G I +S D D+ N V+ SL V + +S++ + ++ + LD Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTP-HVPFKLVSTFKNYYS----LVLDSALDR 415 Query: 526 EELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSV 585 E + + V+ARD G P L + +L V V D NDNAPA P V + Sbjct: 416 ESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEY-------TVFVKENN 468 Query: 586 GAGHVVAKVRAVDADSGYNAWLSYEL 611 G + V A DAD+ NA +SY L Sbjct: 469 PPGCHIFTVSARDADAQENALVSYSL 494 >gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] Length = 1040 Score = 608 bits (1568), Expect = e-174 Identities = 339/802 (42%), Positives = 488/802 (60%), Gaps = 38/802 (4%) Query: 14 LLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGD 73 +LL +L E QLHY+V EE +HG FVG IA+DLGL++ +L R F+ V R Sbjct: 3 VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP 62 Query: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVF 133 L++NL+ G+L+VN +IDRE++C +S C +HLEV +E PL++F V++EV DINDNPP F Sbjct: 63 YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSF 122 Query: 134 PATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLG 193 P + I+ES +RFPLE A D D+G N+L Y ++PN YF LDV T + Sbjct: 123 PEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAE 182 Query: 194 LVLRKLLDREETPELHLLLTATDGG-------------------KPELTGTVQLLITVLD 234 LVL K LDRE+ +LTA DGG + + TGT L I VLD Sbjct: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242 Query: 235 NNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFH 294 +NDN P FD+ +YTV LPEN GTLVI NA+D DEG NG+++YSFSS +SP + F Sbjct: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFG 302 Query: 295 MDPLSGAITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTS 354 + P +G + V G +D+EES +++ V+A D G + HC VLV V+D NDNAP+++ ++ Sbjct: 303 LSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFST 362 Query: 355 LSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALD 414 + + E A PGTV+ L SV DRD NGQV C L VPF+L S+FKNYY++V ++ LD Sbjct: 363 VKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422 Query: 415 RESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHI 474 RE+ +Y L V ARD G P+L + S+ V+V+DVNDNAP F+QP Y V+V ENN PG +I Sbjct: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482 Query: 475 FTVSAGDADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534 + VSA D D NA ++YS++E ++ ++ +YVS+++E+G +YAL+ D+E+L+ FQ Sbjct: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542 Query: 535 VSARDAGVP-PLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAK 593 V ARDAG P L N T+ + ++D+NDNAPA++AP G G RE++PRS G+++ + Sbjct: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602 Query: 594 VRAVDADSGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPR--HRLLVLV 651 V AVDAD G NA L+Y + V FR+ TGE+ T R + P+ + L++ V Sbjct: 603 VAAVDADDGENARLTYSI--VRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660 Query: 652 KDHGEPSLTATATVLVSLVESGQAPKASSRASLG----------IAGPETELVDVNVYLI 701 +DHG+P L++TAT++V LV+ P+ + G G ET L D+ + LI Sbjct: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSL-DLTLILI 719 Query: 702 IAICAVSSLLVLTLLLYTALRCSAPSSEGACS-LVKPTLVCSSAVGSWSFSQQRRQRVCS 760 IA+ +VS + +L +++ A+RC + L +C G + RQ Sbjct: 720 IALGSVSFIFLLAMIV-LAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARAR 778 Query: 761 GEGPPKTDLMAF-SPSLPQGPS 781 + K+D+M S ++P P+ Sbjct: 779 KKKLSKSDIMLVQSSNVPSNPA 800 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.135 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,710,282 Number of Sequences: 37866 Number of extensions: 1478078 Number of successful extensions: 9855 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 187 Number of HSP's successfully gapped in prelim test: 16 Number of HSP's that attempted gapping in prelim test: 2818 Number of HSP's gapped (non-prelim): 726 length of query: 789 length of database: 18,247,518 effective HSP length: 110 effective length of query: 679 effective length of database: 14,082,258 effective search space: 9561853182 effective search space used: 9561853182 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.