BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapiens] (816 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 1602 0.0 gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 1538 0.0 gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi... 1228 0.0 gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] 1228 0.0 gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi... 1227 0.0 gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 1227 0.0 gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi... 1223 0.0 gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] 1223 0.0 gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi... 1214 0.0 gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] 1214 0.0 gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 1211 0.0 gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 1211 0.0 gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap... 1207 0.0 gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi... 1207 0.0 gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi... 1202 0.0 gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] 1199 0.0 gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi... 1195 0.0 gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] 1195 0.0 gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap... 1182 0.0 gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi... 1182 0.0 gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] 1178 0.0 gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi... 1178 0.0 gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap... 1174 0.0 gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi... 1174 0.0 gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap... 1156 0.0 gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi... 1156 0.0 gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi... 815 0.0 gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi... 789 0.0 gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap... 785 0.0 gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 613 e-175 >gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapiens] Length = 816 Score = 1602 bits (4147), Expect = 0.0 Identities = 816/816 (100%), Positives = 816/816 (100%) Query: 1 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP 60 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP Sbjct: 1 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP 60 Query: 61 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV 120 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV Sbjct: 61 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV 120 Query: 121 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD 180 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD Sbjct: 121 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD 180 Query: 181 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE 240 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE Sbjct: 181 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE 240 Query: 241 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE 300 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE Sbjct: 241 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE 300 Query: 301 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE 360 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE Sbjct: 301 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE 360 Query: 361 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY 420 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY Sbjct: 361 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY 420 Query: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD Sbjct: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480 Query: 481 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 540 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG Sbjct: 481 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 540 Query: 541 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS Sbjct: 541 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600 Query: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA Sbjct: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660 Query: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL Sbjct: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720 Query: 721 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT 780 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT Sbjct: 721 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT 780 Query: 781 STDNVSFLILTSIFPSQFSNIKCHIHPLFLYLKIMS 816 STDNVSFLILTSIFPSQFSNIKCHIHPLFLYLKIMS Sbjct: 781 STDNVSFLILTSIFPSQFSNIKCHIHPLFLYLKIMS 816 >gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] Length = 936 Score = 1538 bits (3982), Expect = 0.0 Identities = 784/784 (100%), Positives = 784/784 (100%) Query: 1 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP 60 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP Sbjct: 1 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP 60 Query: 61 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV 120 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV Sbjct: 61 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV 120 Query: 121 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD 180 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD Sbjct: 121 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD 180 Query: 181 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE 240 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE Sbjct: 181 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE 240 Query: 241 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE 300 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE Sbjct: 241 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE 300 Query: 301 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE 360 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE Sbjct: 301 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE 360 Query: 361 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY 420 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY Sbjct: 361 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY 420 Query: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD Sbjct: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480 Query: 481 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 540 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG Sbjct: 481 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 540 Query: 541 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS Sbjct: 541 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600 Query: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA Sbjct: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660 Query: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL Sbjct: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720 Query: 721 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT 780 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT Sbjct: 721 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT 780 Query: 781 STDN 784 STDN Sbjct: 781 STDN 784 >gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapiens] Length = 798 Score = 1228 bits (3178), Expect = 0.0 Identities = 631/779 (81%), Positives = 678/779 (87%) Query: 7 GSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 66 G RLLLL LLLA W+AG+GQLHYS+ EEAKHGTFVGRIAQDLGLELAELVPRLFRVA Sbjct: 8 GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 Query: 67 SKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDIN 126 SKGRG LLEVNLQNGILFVNSRIDREELCRR AECSIHLEVIVDRPLQVFHV+V V+DIN Sbjct: 68 SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127 Query: 127 DNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEE 186 DNPP F ++ L I ESR DSRFPLEGASD DIG NA L YRL+PNEYF L+ ++E Sbjct: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDE 187 Query: 187 ETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIY 246 L L+LRKSLDREE E L++ ATDGGKPELTGTVQLLI VLDANDNAP FD++IY Sbjct: 188 LVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIY 247 Query: 247 NVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGE 306 VRLLEN P+GTLVIKLNASD DEG+N +IVY FSN + +VKSKF I+ TG+I V G Sbjct: 248 KVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGY 307 Query: 307 LDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLST 366 +D+E+ SYEI ++ +DK PLSGHC+V+V++ D NDN P++ +L LP++EDAPL T Sbjct: 308 IDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGT 367 Query: 367 VIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTA 426 VIALISVSD+D G NG VTCSL HVPFKLVSTFKNYYSLVLDSALDRESVS YELVVTA Sbjct: 368 VIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 Query: 427 RDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQEN 486 RDGGSPSLWATASVSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQEN Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQEN 487 Query: 487 ALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGS 546 ALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQV+ARDAGVPPLGS Sbjct: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGS 547 Query: 547 NVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWL 606 NVTLQVFVLDENDNAPALL PR GGTGGAVSELVP SVG GHVVAKVRAVD DSGYNAWL Sbjct: 548 NVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWL 607 Query: 607 SYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLV 666 SYELQP G ARIPFRVGLYTGEISTTR+LDET+APRHRLLVLVKDHGEP LTATATVLV Sbjct: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLV 667 Query: 667 SLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQP 726 SLVESGQAPKASSRA GAVGP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA P Sbjct: 668 SLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALP 727 Query: 727 TEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTDNV 785 TE C GKPTL+CSSAVGSWSYSQQRR RVCSGE PPKTDLMAFSPSLP D + Sbjct: 728 TEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQL 786 >gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] Length = 947 Score = 1228 bits (3178), Expect = 0.0 Identities = 631/779 (81%), Positives = 678/779 (87%) Query: 7 GSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 66 G RLLLL LLLA W+AG+GQLHYS+ EEAKHGTFVGRIAQDLGLELAELVPRLFRVA Sbjct: 8 GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 Query: 67 SKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDIN 126 SKGRG LLEVNLQNGILFVNSRIDREELCRR AECSIHLEVIVDRPLQVFHV+V V+DIN Sbjct: 68 SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127 Query: 127 DNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEE 186 DNPP F ++ L I ESR DSRFPLEGASD DIG NA L YRL+PNEYF L+ ++E Sbjct: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDE 187 Query: 187 ETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIY 246 L L+LRKSLDREE E L++ ATDGGKPELTGTVQLLI VLDANDNAP FD++IY Sbjct: 188 LVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIY 247 Query: 247 NVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGE 306 VRLLEN P+GTLVIKLNASD DEG+N +IVY FSN + +VKSKF I+ TG+I V G Sbjct: 248 KVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGY 307 Query: 307 LDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLST 366 +D+E+ SYEI ++ +DK PLSGHC+V+V++ D NDN P++ +L LP++EDAPL T Sbjct: 308 IDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGT 367 Query: 367 VIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTA 426 VIALISVSD+D G NG VTCSL HVPFKLVSTFKNYYSLVLDSALDRESVS YELVVTA Sbjct: 368 VIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 Query: 427 RDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQEN 486 RDGGSPSLWATASVSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQEN Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQEN 487 Query: 487 ALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGS 546 ALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQV+ARDAGVPPLGS Sbjct: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGS 547 Query: 547 NVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWL 606 NVTLQVFVLDENDNAPALL PR GGTGGAVSELVP SVG GHVVAKVRAVD DSGYNAWL Sbjct: 548 NVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWL 607 Query: 607 SYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLV 666 SYELQP G ARIPFRVGLYTGEISTTR+LDET+APRHRLLVLVKDHGEP LTATATVLV Sbjct: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLV 667 Query: 667 SLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQP 726 SLVESGQAPKASSRA GAVGP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA P Sbjct: 668 SLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALP 727 Query: 727 TEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTDNV 785 TE C GKPTL+CSSAVGSWSYSQQRR RVCSGE PPKTDLMAFSPSLP D + Sbjct: 728 TEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQL 786 >gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapiens] Length = 814 Score = 1227 bits (3175), Expect = 0.0 Identities = 631/784 (80%), Positives = 680/784 (86%), Gaps = 1/784 (0%) Query: 1 MVYSRRGSLGS-RLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 M Y RG LGS RLLLL LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK DLLEV+LQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKD+NDNPP F ++Q+LF+ ESRMPDSRFPLEGASD D+GAN+ L YRL+ ++YF L Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DV + +E +ELVLRKSLDRE+ H L + ATDGGKPELTGTVQLL+ VLD NDNAP Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 F++S Y VR+ ENA +GT VIKLNASD DEG N I Y F++LV V F I+ NTG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI + G LD+E N Y+I IDA DK P++GHC V+V++LD NDN PE+A+T+L LPV+ Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDA TVIALISV+D DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRE VS Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LSSY+SVH ESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGTGGA S+LVPRSVGAGHVVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQPA S RIPFRVGLYTGEISTTR LDE ++PRHRLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPKASSR SAG +GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCSA PTE C GKPTL+CSSAVGSWSYSQQ+ QRVCSGE PPKTDLMAFSP LP Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 Query: 780 TSTD 783 S D Sbjct: 781 GSVD 784 >gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1227 bits (3175), Expect = 0.0 Identities = 631/784 (80%), Positives = 680/784 (86%), Gaps = 1/784 (0%) Query: 1 MVYSRRGSLGS-RLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 M Y RG LGS RLLLL LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK DLLEV+LQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKD+NDNPP F ++Q+LF+ ESRMPDSRFPLEGASD D+GAN+ L YRL+ ++YF L Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DV + +E +ELVLRKSLDRE+ H L + ATDGGKPELTGTVQLL+ VLD NDNAP Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 F++S Y VR+ ENA +GT VIKLNASD DEG N I Y F++LV V F I+ NTG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI + G LD+E N Y+I IDA DK P++GHC V+V++LD NDN PE+A+T+L LPV+ Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDA TVIALISV+D DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRE VS Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LSSY+SVH ESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGTGGA S+LVPRSVGAGHVVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQPA S RIPFRVGLYTGEISTTR LDE ++PRHRLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPKASSR SAG +GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCSA PTE C GKPTL+CSSAVGSWSYSQQ+ QRVCSGE PPKTDLMAFSP LP Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 Query: 780 TSTD 783 S D Sbjct: 781 GSVD 784 >gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1223 bits (3164), Expect = 0.0 Identities = 629/786 (80%), Positives = 690/786 (87%), Gaps = 2/786 (0%) Query: 1 MVYSRRGSLGSRLLLLWLLL-AYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 MV+SRRG LG+R LLLWLLL A W+ GSGQLHYSIPEEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK DLLEVNLQNGILFVNSRIDREELC+ AECSIHLE+I DRPLQVFHVE Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKDINDNPP F +EQ +FI ESR+ +SRFP+EGA+D DIGANA L Y L+P++YF L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DV+ ++E + L L LRK LDREET E LL+ ATDGGKPEL GTV+LLI VLD NDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 FD+++Y V LLE +GTLV LNASDADEG+N E+V+ F + + D++ KF ++S++G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI++ +LDYE+ SYEI + A+DK + P+S HCKV+VK+LDVNDN PE+A+T+L+LP++ Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDAPLSTVIALI+VSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRES+SV Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LS+YVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGT GAVSELVPR VGAGHVVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQPA G ARIPFRVGLYTGEISTTR LDE + R+RLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPKASSRAS G GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSL-PQG 778 LRCS PTE GKPTL+CSSA+GSWS SQQRRQRVCS E PPKTDLMAFSP L P Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 779 PTSTDN 784 TS N Sbjct: 781 NTSERN 786 >gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1223 bits (3164), Expect = 0.0 Identities = 629/786 (80%), Positives = 690/786 (87%), Gaps = 2/786 (0%) Query: 1 MVYSRRGSLGSRLLLLWLLL-AYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 MV+SRRG LG+R LLLWLLL A W+ GSGQLHYSIPEEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK DLLEVNLQNGILFVNSRIDREELC+ AECSIHLE+I DRPLQVFHVE Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKDINDNPP F +EQ +FI ESR+ +SRFP+EGA+D DIGANA L Y L+P++YF L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DV+ ++E + L L LRK LDREET E LL+ ATDGGKPEL GTV+LLI VLD NDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 FD+++Y V LLE +GTLV LNASDADEG+N E+V+ F + + D++ KF ++S++G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI++ +LDYE+ SYEI + A+DK + P+S HCKV+VK+LDVNDN PE+A+T+L+LP++ Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDAPLSTVIALI+VSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRES+SV Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LS+YVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGT GAVSELVPR VGAGHVVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQPA G ARIPFRVGLYTGEISTTR LDE + R+RLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPKASSRAS G GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSL-PQG 778 LRCS PTE GKPTL+CSSA+GSWS SQQRRQRVCS E PPKTDLMAFSP L P Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 779 PTSTDN 784 TS N Sbjct: 781 NTSERN 786 >gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapiens] Length = 803 Score = 1214 bits (3140), Expect = 0.0 Identities = 622/780 (79%), Positives = 675/780 (86%), Gaps = 1/780 (0%) Query: 1 MVYSRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 MV++ LG + LLL LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFR+ASK R DLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V V+DINDNPP F +EQR+ I ESR+PDS FPLEGASD D+G+N+ L Y+L+ +EYF L Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DVK N ++ + L+L+KSLDREE H L + ATDGGKPELTGTVQLL+ VLD NDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 F++S Y VR+ ENA +GT VI+LNASD DEG N I Y F++LV V F I+ NTG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI + G LD+E N Y+I IDA DK P++GHC V+V++LD NDN PE+A+T+L LPV+ Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDA TVIALISV+D DSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRESVS Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LSSY+SVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGTGGAVSELVPRS+GAG VVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQP SAR PFRVGLYTGEISTTR LDE ++PRHRLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPKASSRAS GA GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCSA PTE CT KPTL+CSSAVGSWSYSQQRRQRVCSGE PPK DLMAFSPSL P Sbjct: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 >gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1214 bits (3140), Expect = 0.0 Identities = 622/780 (79%), Positives = 675/780 (86%), Gaps = 1/780 (0%) Query: 1 MVYSRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 MV++ LG + LLL LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFR+ASK R DLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V V+DINDNPP F +EQR+ I ESR+PDS FPLEGASD D+G+N+ L Y+L+ +EYF L Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DVK N ++ + L+L+KSLDREE H L + ATDGGKPELTGTVQLL+ VLD NDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 F++S Y VR+ ENA +GT VI+LNASD DEG N I Y F++LV V F I+ NTG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI + G LD+E N Y+I IDA DK P++GHC V+V++LD NDN PE+A+T+L LPV+ Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDA TVIALISV+D DSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRESVS Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LSSY+SVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGTGGAVSELVPRS+GAG VVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQP SAR PFRVGLYTGEISTTR LDE ++PRHRLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPKASSRAS GA GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCSA PTE CT KPTL+CSSAVGSWSYSQQRRQRVCSGE PPK DLMAFSPSL P Sbjct: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 >gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1211 bits (3134), Expect = 0.0 Identities = 623/784 (79%), Positives = 679/784 (86%), Gaps = 1/784 (0%) Query: 1 MVYSRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 M++S R G++ LLL LLLA + GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK GDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKDINDN P F + LFI ESR P SRF LEGASD DIG N+ L Y L+ EYF L Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DVK N+EE L LVL+K+L+RE+T +H LL+ A DGGKPELTGT QL I VLD NDNAP Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 F+++IY VRLLENAP+GTLV+ +NA+D DEG+NK+I Y F+ + D+ SKF ++ G Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 +I V G +D+E+ SYEI ++A DK P+S HC V+++++D+NDN PE+ I +L LPV Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 ED+PLSTVIALISVSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDS LDRESVS Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAF+Q +YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL+PRVGG GGAVSELVPRSVGAGHVVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQP G ARIPFRVGLYTGEISTTR+LDE +APRHRLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPKASS+ASAGA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCSA PTE C GKPTL+CSSAVGSWSYSQQR+QRVCSGE PKTDLMAFSPSLP P Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 Query: 780 TSTD 783 S D Sbjct: 781 ISRD 784 >gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1211 bits (3134), Expect = 0.0 Identities = 623/784 (79%), Positives = 679/784 (86%), Gaps = 1/784 (0%) Query: 1 MVYSRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 M++S R G++ LLL LLLA + GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK GDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKDINDN P F + LFI ESR P SRF LEGASD DIG N+ L Y L+ EYF L Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DVK N+EE L LVL+K+L+RE+T +H LL+ A DGGKPELTGT QL I VLD NDNAP Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 F+++IY VRLLENAP+GTLV+ +NA+D DEG+NK+I Y F+ + D+ SKF ++ G Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 +I V G +D+E+ SYEI ++A DK P+S HC V+++++D+NDN PE+ I +L LPV Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 ED+PLSTVIALISVSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDS LDRESVS Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAF+Q +YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL+PRVGG GGAVSELVPRSVGAGHVVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQP G ARIPFRVGLYTGEISTTR+LDE +APRHRLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPKASS+ASAGA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCSA PTE C GKPTL+CSSAVGSWSYSQQR+QRVCSGE PKTDLMAFSPSLP P Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 Query: 780 TSTD 783 S D Sbjct: 781 ISRD 784 >gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1207 bits (3122), Expect = 0.0 Identities = 615/777 (79%), Positives = 675/777 (86%), Gaps = 1/777 (0%) Query: 1 MVYSRRGSLGSRLLLLWLL-LAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 M+ S +G R LLLWLL LA W+ GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK GDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V V+DINDNPP F ++R+ I ESR P++RFPL+GASD DIG N+ L YRL+PN+YF L Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 D + + E+ + L LVLRK+LDREE QEH LL+ A+DGGKPELTGTVQLLI +LD NDNAP Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 EF +S+Y V +LENA +GTLVIKLNA+D D+G N +IVY F V V F IN N G Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI+ G+LD+E+ YEI+++A+DK P++GHC ++V++LDVNDN PE+ IT+L LP++ Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 ED S +IALISVSDRDSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRESVS Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATASVSV VADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA+ Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD+ Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL P G GG VSEL+PRSVGAGHVVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQ A ARIPFRVGLYTGEISTTR LDE +AP HRLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVL+SLVESGQAP+ASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLP 776 LRCSA PTE C GKPTL+CSSA GSWSYSQQRR RVCSGE P KTDLMAFSPSLP Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLP 777 >gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1207 bits (3122), Expect = 0.0 Identities = 615/777 (79%), Positives = 675/777 (86%), Gaps = 1/777 (0%) Query: 1 MVYSRRGSLGSRLLLLWLL-LAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 M+ S +G R LLLWLL LA W+ GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK GDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V V+DINDNPP F ++R+ I ESR P++RFPL+GASD DIG N+ L YRL+PN+YF L Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 D + + E+ + L LVLRK+LDREE QEH LL+ A+DGGKPELTGTVQLLI +LD NDNAP Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 EF +S+Y V +LENA +GTLVIKLNA+D D+G N +IVY F V V F IN N G Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI+ G+LD+E+ YEI+++A+DK P++GHC ++V++LDVNDN PE+ IT+L LP++ Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 ED S +IALISVSDRDSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRESVS Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATASVSV VADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA+ Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD+ Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL P G GG VSEL+PRSVGAGHVVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQ A ARIPFRVGLYTGEISTTR LDE +AP HRLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVL+SLVESGQAP+ASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLP 776 LRCSA PTE C GKPTL+CSSA GSWSYSQQRR RVCSGE P KTDLMAFSPSLP Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLP 777 >gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapiens] Length = 789 Score = 1202 bits (3110), Expect = 0.0 Identities = 617/777 (79%), Positives = 671/777 (86%) Query: 10 GSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKG 69 G LLL ++LA W+AG GQLHYS+PEEAKHG FVGRIAQDLGLELAELVPRLFR K Sbjct: 11 GRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKF 70 Query: 70 RGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNP 129 RGDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIV+RPLQVFHV+V VKDINDNP Sbjct: 71 RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNP 130 Query: 130 PRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETN 189 P F ++ LFI ESR DSRFPLEGASD DIG NA L YRL+PNEYF LDV T+ ++ Sbjct: 131 PVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVK 190 Query: 190 FLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVR 249 L LVLRK LDREET E LL+ ATDGGKPELTGTVQLLI VLD NDNAP FD+++Y V+ Sbjct: 191 PLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVK 250 Query: 250 LLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDY 309 L EN GTLVI NASD DEG+N +I+Y FS+ V D+KSKF ++ +G I V G +D+ Sbjct: 251 LPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDF 310 Query: 310 EDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIA 369 E+ +++I ++A+DK PL+GHC V+V+++DVNDN P++ +T+L LP+ EDA TVI Sbjct: 311 EESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVIT 370 Query: 370 LISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDG 429 LISV DRD G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRESVS YELVVTARDG Sbjct: 371 LISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDG 430 Query: 430 GSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALV 489 GSPSLWATASVSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQ+NALV Sbjct: 431 GSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALV 490 Query: 490 SYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVT 549 SYSLVE RVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVT Sbjct: 491 SYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVT 550 Query: 550 LQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYE 609 LQVFVLDENDNAPALL PRVGGTGGAV ELVPRSVGAGHVVAKVRAVD DSGYNAWLSYE Sbjct: 551 LQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYE 610 Query: 610 LQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLV 669 LQP A IPFRVGLYTGEISTTR+LDET+APRHRLLVLVKDHGEP LTATATVLVSLV Sbjct: 611 LQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLV 670 Query: 670 ESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQPTEA 729 ESGQAPKASSRAS G GPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +E Sbjct: 671 ESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEG 730 Query: 730 VCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTDNVS 786 C+ KPTL+CSSAVGSWS+SQQRRQRVCSGE PPKTDLMAFSPSLPQGP+STDNVS Sbjct: 731 ACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNVS 787 >gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] Length = 937 Score = 1199 bits (3102), Expect = 0.0 Identities = 615/775 (79%), Positives = 669/775 (86%) Query: 10 GSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKG 69 G LLL ++LA W+AG GQLHYS+PEEAKHG FVGRIAQDLGLELAELVPRLFR K Sbjct: 11 GRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKF 70 Query: 70 RGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNP 129 RGDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIV+RPLQVFHV+V VKDINDNP Sbjct: 71 RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNP 130 Query: 130 PRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETN 189 P F ++ LFI ESR DSRFPLEGASD DIG NA L YRL+PNEYF LDV T+ ++ Sbjct: 131 PVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVK 190 Query: 190 FLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVR 249 L LVLRK LDREET E LL+ ATDGGKPELTGTVQLLI VLD NDNAP FD+++Y V+ Sbjct: 191 PLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVK 250 Query: 250 LLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDY 309 L EN GTLVI NASD DEG+N +I+Y FS+ V D+KSKF ++ +G I V G +D+ Sbjct: 251 LPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDF 310 Query: 310 EDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIA 369 E+ +++I ++A+DK PL+GHC V+V+++DVNDN P++ +T+L LP+ EDA TVI Sbjct: 311 EESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVIT 370 Query: 370 LISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDG 429 LISV DRD G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRESVS YELVVTARDG Sbjct: 371 LISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDG 430 Query: 430 GSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALV 489 GSPSLWATASVSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQ+NALV Sbjct: 431 GSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALV 490 Query: 490 SYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVT 549 SYSLVE RVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVT Sbjct: 491 SYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVT 550 Query: 550 LQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYE 609 LQVFVLDENDNAPALL PRVGGTGGAV ELVPRSVGAGHVVAKVRAVD DSGYNAWLSYE Sbjct: 551 LQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYE 610 Query: 610 LQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLV 669 LQP A IPFRVGLYTGEISTTR+LDET+APRHRLLVLVKDHGEP LTATATVLVSLV Sbjct: 611 LQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLV 670 Query: 670 ESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQPTEA 729 ESGQAPKASSRAS G GPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +E Sbjct: 671 ESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEG 730 Query: 730 VCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTDN 784 C+ KPTL+CSSAVGSWS+SQQRRQRVCSGE PPKTDLMAFSPSLPQGP+STDN Sbjct: 731 ACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDN 785 >gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1195 bits (3092), Expect = 0.0 Identities = 616/779 (79%), Positives = 667/779 (85%) Query: 5 RRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFR 64 RRG LL LLLA W+ GSGQL YS+PEEAKHGTFVGRIAQDLGLEL ELVPRLFR Sbjct: 6 RRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFR 65 Query: 65 VASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKD 124 VASK GDLLEVNLQNGILFVNSRIDREELC R AECSIH+EVIVDRPLQVFHVEV VKD Sbjct: 66 VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKD 125 Query: 125 INDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTN 184 INDNPP F + + ESR+ DSRFPLEGASD DIG NA L Y+L+ +E+F LD++ N Sbjct: 126 INDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAN 185 Query: 185 EEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKS 244 +E + L LVL KSLDREET E LL++ATDGGKPELTGTVQ+LI VLD NDN P F +S Sbjct: 186 DELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQS 245 Query: 245 IYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVN 304 +Y V+LLEN +GTLV+KLNASDADEG N EIVY + V +++KF I+ +GEI+ Sbjct: 246 VYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTK 305 Query: 305 GELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPL 364 G+LDYE+ SYEI + A DK T +SGHCK+ +KL+D+NDNTPE++IT+L LP+ E+A L Sbjct: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365 Query: 365 STVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVV 424 TVIALI+VSDRDSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRESVS YELVV Sbjct: 366 GTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425 Query: 425 TARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQ 484 TARDGGSPSLWAT SVS+EVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQ Sbjct: 426 TARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ 485 Query: 485 ENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 544 ENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL Sbjct: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 545 Query: 545 GSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNA 604 GSNVTLQVFVLDENDNAPALL PR G GAVSELVP SVGAGHVVAKVRAVD DSGYNA Sbjct: 546 GSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNA 605 Query: 605 WLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATV 664 WLSYELQ GSARIPFRVGLYTGEISTTR+LDE ++PRHRLLVLVKDHGEP LTATATV Sbjct: 606 WLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 665 Query: 665 LVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA 724 LVSLVESGQAPKASSRA GA G EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS Sbjct: 666 LVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSV 725 Query: 725 QPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTD 783 PTE GKPTL+CSSAVGSWSYSQQRRQRVCSGE PPKTDLMAFSPSL QGP S + Sbjct: 726 PPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAE 784 >gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1195 bits (3092), Expect = 0.0 Identities = 616/779 (79%), Positives = 667/779 (85%) Query: 5 RRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFR 64 RRG LL LLLA W+ GSGQL YS+PEEAKHGTFVGRIAQDLGLEL ELVPRLFR Sbjct: 6 RRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFR 65 Query: 65 VASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKD 124 VASK GDLLEVNLQNGILFVNSRIDREELC R AECSIH+EVIVDRPLQVFHVEV VKD Sbjct: 66 VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKD 125 Query: 125 INDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTN 184 INDNPP F + + ESR+ DSRFPLEGASD DIG NA L Y+L+ +E+F LD++ N Sbjct: 126 INDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAN 185 Query: 185 EEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKS 244 +E + L LVL KSLDREET E LL++ATDGGKPELTGTVQ+LI VLD NDN P F +S Sbjct: 186 DELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQS 245 Query: 245 IYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVN 304 +Y V+LLEN +GTLV+KLNASDADEG N EIVY + V +++KF I+ +GEI+ Sbjct: 246 VYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTK 305 Query: 305 GELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPL 364 G+LDYE+ SYEI + A DK T +SGHCK+ +KL+D+NDNTPE++IT+L LP+ E+A L Sbjct: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365 Query: 365 STVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVV 424 TVIALI+VSDRDSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRESVS YELVV Sbjct: 366 GTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425 Query: 425 TARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQ 484 TARDGGSPSLWAT SVS+EVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQ Sbjct: 426 TARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ 485 Query: 485 ENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 544 ENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL Sbjct: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 545 Query: 545 GSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNA 604 GSNVTLQVFVLDENDNAPALL PR G GAVSELVP SVGAGHVVAKVRAVD DSGYNA Sbjct: 546 GSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNA 605 Query: 605 WLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATV 664 WLSYELQ GSARIPFRVGLYTGEISTTR+LDE ++PRHRLLVLVKDHGEP LTATATV Sbjct: 606 WLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 665 Query: 665 LVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA 724 LVSLVESGQAPKASSRA GA G EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS Sbjct: 666 LVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSV 725 Query: 725 QPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTD 783 PTE GKPTL+CSSAVGSWSYSQQRRQRVCSGE PPKTDLMAFSPSL QGP S + Sbjct: 726 PPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAE 784 >gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sapiens] Length = 810 Score = 1182 bits (3059), Expect = 0.0 Identities = 609/777 (78%), Positives = 665/777 (85%), Gaps = 3/777 (0%) Query: 3 YSRRGSLGSRLLLLWLLLA-YWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPR 61 + RRG LG+ L LWLLL +W+ GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELV R Sbjct: 4 FQRRG-LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQR 62 Query: 62 LFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVA 121 LFRVASK GDLLEVNLQNGILFVNSRIDREELC + AECSIHLEVIVDRPLQVFHV V Sbjct: 63 LFRVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVE 122 Query: 122 VKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDV 181 VKDINDNPP FS +EQ+L I ES+ DSRFPLEGASD DI NA L YRL+ NEYF LD Sbjct: 123 VKDINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDS 182 Query: 182 KTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEF 241 TN ++ L L+L+KSLDRE+T E LL+ ATDGGKPELTGTV+LL+ VLD NDN PEF Sbjct: 183 PTNGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEF 242 Query: 242 DKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEI 301 DKS Y V L+ENA TLV+KLNA+D DEG+N E+ Y + + + + F ++ N GE+ Sbjct: 243 DKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEV 301 Query: 302 KVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKED 361 +VNG LDYE+ Y+I + A DK T P++GHC V V++LD NDN+PE+A+T+L LPV+ED Sbjct: 302 RVNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVRED 361 Query: 362 APLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYE 421 A STVIALISVSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDSALDRE+V YE Sbjct: 362 AQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYE 421 Query: 422 LVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDA 481 LVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSARDA Sbjct: 422 LVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDA 481 Query: 482 DAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGV 541 DAQENALVSYSLVERR+G+R LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGV Sbjct: 482 DAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGV 541 Query: 542 PPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSG 601 PPL SNVTLQVFVLDENDNAPALL + G GGAV++LVPRSVGAGHVVAKVRAVD DSG Sbjct: 542 PPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSG 601 Query: 602 YNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTAT 661 YNAWLSYELQPA G +RIPFRVGLYTGEISTTR+LDE ++PRHRLLVLVKDHGEP LTAT Sbjct: 602 YNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTAT 661 Query: 662 ATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALR 721 ATVLVSLVESGQAPKASSR AGA PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL Sbjct: 662 ATVLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALW 721 Query: 722 CSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQG 778 SA PTE C GKPTL+CS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSLP G Sbjct: 722 WSATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLG 778 >gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapiens] Length = 949 Score = 1182 bits (3059), Expect = 0.0 Identities = 609/777 (78%), Positives = 665/777 (85%), Gaps = 3/777 (0%) Query: 3 YSRRGSLGSRLLLLWLLLA-YWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPR 61 + RRG LG+ L LWLLL +W+ GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELV R Sbjct: 4 FQRRG-LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQR 62 Query: 62 LFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVA 121 LFRVASK GDLLEVNLQNGILFVNSRIDREELC + AECSIHLEVIVDRPLQVFHV V Sbjct: 63 LFRVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVE 122 Query: 122 VKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDV 181 VKDINDNPP FS +EQ+L I ES+ DSRFPLEGASD DI NA L YRL+ NEYF LD Sbjct: 123 VKDINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDS 182 Query: 182 KTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEF 241 TN ++ L L+L+KSLDRE+T E LL+ ATDGGKPELTGTV+LL+ VLD NDN PEF Sbjct: 183 PTNGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEF 242 Query: 242 DKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEI 301 DKS Y V L+ENA TLV+KLNA+D DEG+N E+ Y + + + + F ++ N GE+ Sbjct: 243 DKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEV 301 Query: 302 KVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKED 361 +VNG LDYE+ Y+I + A DK T P++GHC V V++LD NDN+PE+A+T+L LPV+ED Sbjct: 302 RVNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVRED 361 Query: 362 APLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYE 421 A STVIALISVSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDSALDRE+V YE Sbjct: 362 AQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYE 421 Query: 422 LVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDA 481 LVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSARDA Sbjct: 422 LVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDA 481 Query: 482 DAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGV 541 DAQENALVSYSLVERR+G+R LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGV Sbjct: 482 DAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGV 541 Query: 542 PPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSG 601 PPL SNVTLQVFVLDENDNAPALL + G GGAV++LVPRSVGAGHVVAKVRAVD DSG Sbjct: 542 PPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSG 601 Query: 602 YNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTAT 661 YNAWLSYELQPA G +RIPFRVGLYTGEISTTR+LDE ++PRHRLLVLVKDHGEP LTAT Sbjct: 602 YNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTAT 661 Query: 662 ATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALR 721 ATVLVSLVESGQAPKASSR AGA PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL Sbjct: 662 ATVLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALW 721 Query: 722 CSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQG 778 SA PTE C GKPTL+CS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSLP G Sbjct: 722 WSATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLG 778 >gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] Length = 842 Score = 1178 bits (3048), Expect = 0.0 Identities = 612/784 (78%), Positives = 668/784 (85%), Gaps = 1/784 (0%) Query: 1 MVYSRRGSL-GSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 M+YS RG G LLL L+LA W GSGQLHYS+PEEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLF++ SKGRGDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKDINDNPP F ++ LFI ESR DSRFPLEGASD DIG NA L YRL+PNEYF L Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DV T+ ++ L LVLRK LDREET E LL+ ATDGGKPELTGTVQLLI VLD NDNAP Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 FD+++Y V+L EN GTLVI NASD DEG+N +I+Y FS+ V D+KSKF ++ +G Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 I V G +D+E+ +++I ++A+DK PL+GHC ++V+++DVNDN P++ I TL +PVK Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDA L TVIALISV D D+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRESVS Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQ +YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERR+GER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GAVSE+V RSVGAG VV KVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQP SA IPFRVGLYTGEISTTR+LDET+APR RLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPK+SSRAS GA GPE LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCSA PTE C GKPTL+CSSAVGSWSYSQQRRQRVCSGE KTDLMAFSP L Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 Query: 780 TSTD 783 ST+ Sbjct: 781 GSTE 784 >gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1178 bits (3048), Expect = 0.0 Identities = 612/784 (78%), Positives = 668/784 (85%), Gaps = 1/784 (0%) Query: 1 MVYSRRGSL-GSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 M+YS RG G LLL L+LA W GSGQLHYS+PEEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLF++ SKGRGDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKDINDNPP F ++ LFI ESR DSRFPLEGASD DIG NA L YRL+PNEYF L Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DV T+ ++ L LVLRK LDREET E LL+ ATDGGKPELTGTVQLLI VLD NDNAP Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 FD+++Y V+L EN GTLVI NASD DEG+N +I+Y FS+ V D+KSKF ++ +G Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 I V G +D+E+ +++I ++A+DK PL+GHC ++V+++DVNDN P++ I TL +PVK Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDA L TVIALISV D D+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRESVS Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQ +YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERR+GER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GAVSE+V RSVGAG VV KVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQP SA IPFRVGLYTGEISTTR+LDET+APR RLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPK+SSRAS GA GPE LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCSA PTE C GKPTL+CSSAVGSWSYSQQRRQRVCSGE KTDLMAFSP L Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 Query: 780 TSTD 783 ST+ Sbjct: 781 GSTE 784 >gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sapiens] Length = 844 Score = 1174 bits (3036), Expect = 0.0 Identities = 612/777 (78%), Positives = 664/777 (85%), Gaps = 2/777 (0%) Query: 4 SRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRL 62 SR LG + LLL LLLA W+ GSGQLHYS+ EEA+HGTFVGRIAQDLGLELAELV RL Sbjct: 3 SRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRL 62 Query: 63 FRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAV 122 FRVASK GDLLEVNLQNGILFVNSRIDREELC R ECSIHLEVIVDRPLQVFHV+V V Sbjct: 63 FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEV 122 Query: 123 KDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVK 182 KDINDNPPRFS EQ+L I ESR+ DSRFPLEGASD D+G NA L Y+L+PNEYF LD+ Sbjct: 123 KDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDII 182 Query: 183 TNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFD 242 +++ F LVLRK LDREE + +LL+ ATDGGKPE TG+V LLI VLDANDNAP FD Sbjct: 183 NKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFD 242 Query: 243 KSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIK 302 + +Y V++ EN + TLVI+LNASD+DEGINKE++Y FS+LV ++ KF IN TGEIK Sbjct: 243 RPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIK 302 Query: 303 VNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDA 362 VN +D+ED N+YEI++D DK P+ GHC V+V+LLD NDN+PE+ +T+L LPVKEDA Sbjct: 303 VNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDA 362 Query: 363 PLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYEL 422 + TVIALISVSD DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRE VS YEL Sbjct: 363 QVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYEL 422 Query: 423 VVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDAD 482 VVTARDGGSP LWATASVSVEVADVNDNAPAFAQ +YTVFVKENNPPGCHIFTVSA DAD Sbjct: 423 VVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDAD 482 Query: 483 AQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVP 542 AQENALVSYSLVERR+GER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD GVP Sbjct: 483 AQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVP 542 Query: 543 PLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGY 602 PLGSN+TLQVFVLDENDNAPALL G GGAVSELV RSV AGHVVAKVRAVD DSGY Sbjct: 543 PLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGY 602 Query: 603 NAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATA 662 NAWLSYELQ A ARIPFRVGLYTGEISTTR+LDET++PR RLLVLVKDHGEP LTATA Sbjct: 603 NAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATA 662 Query: 663 TVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 722 TVLVSLVE QAPKASSRAS G V PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRC Sbjct: 663 TVLVSLVEGSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 721 Query: 723 SAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 SA PTE C KPTL+CSSAVGSWSYSQQRRQRVCSGE PK DLMAFSPSLP P Sbjct: 722 SAAPTEGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCP 778 >gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1174 bits (3036), Expect = 0.0 Identities = 612/777 (78%), Positives = 664/777 (85%), Gaps = 2/777 (0%) Query: 4 SRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRL 62 SR LG + LLL LLLA W+ GSGQLHYS+ EEA+HGTFVGRIAQDLGLELAELV RL Sbjct: 3 SRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRL 62 Query: 63 FRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAV 122 FRVASK GDLLEVNLQNGILFVNSRIDREELC R ECSIHLEVIVDRPLQVFHV+V V Sbjct: 63 FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEV 122 Query: 123 KDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVK 182 KDINDNPPRFS EQ+L I ESR+ DSRFPLEGASD D+G NA L Y+L+PNEYF LD+ Sbjct: 123 KDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDII 182 Query: 183 TNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFD 242 +++ F LVLRK LDREE + +LL+ ATDGGKPE TG+V LLI VLDANDNAP FD Sbjct: 183 NKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFD 242 Query: 243 KSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIK 302 + +Y V++ EN + TLVI+LNASD+DEGINKE++Y FS+LV ++ KF IN TGEIK Sbjct: 243 RPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIK 302 Query: 303 VNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDA 362 VN +D+ED N+YEI++D DK P+ GHC V+V+LLD NDN+PE+ +T+L LPVKEDA Sbjct: 303 VNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDA 362 Query: 363 PLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYEL 422 + TVIALISVSD DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRE VS YEL Sbjct: 363 QVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYEL 422 Query: 423 VVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDAD 482 VVTARDGGSP LWATASVSVEVADVNDNAPAFAQ +YTVFVKENNPPGCHIFTVSA DAD Sbjct: 423 VVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDAD 482 Query: 483 AQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVP 542 AQENALVSYSLVERR+GER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD GVP Sbjct: 483 AQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVP 542 Query: 543 PLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGY 602 PLGSN+TLQVFVLDENDNAPALL G GGAVSELV RSV AGHVVAKVRAVD DSGY Sbjct: 543 PLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGY 602 Query: 603 NAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATA 662 NAWLSYELQ A ARIPFRVGLYTGEISTTR+LDET++PR RLLVLVKDHGEP LTATA Sbjct: 603 NAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATA 662 Query: 663 TVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 722 TVLVSLVE QAPKASSRAS G V PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRC Sbjct: 663 TVLVSLVEGSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 721 Query: 723 SAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 SA PTE C KPTL+CSSAVGSWSYSQQRRQRVCSGE PK DLMAFSPSLP P Sbjct: 722 SAAPTEGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCP 778 >gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sapiens] Length = 792 Score = 1156 bits (2991), Expect = 0.0 Identities = 598/775 (77%), Positives = 657/775 (84%) Query: 1 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP 60 ++ RG RLLL LLLA W+ GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELVP Sbjct: 2 VIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVP 61 Query: 61 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV 120 RLFRVASK GDLLEVNLQNGILFVNSRIDRE+LC R AECSIHLEVIVDRPLQVFHV+V Sbjct: 62 RLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDV 121 Query: 121 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD 180 VKDINDNPP F +EQ++ + ES DS FPLEGASD DIG N+ L Y L+ NE F+L Sbjct: 122 EVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELK 181 Query: 181 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE 240 +KT ++++ ELVLRK LDRE+T + LL++ DGGKPELTG+VQ+ I VLD NDN P Sbjct: 182 IKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPA 241 Query: 241 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE 300 FDK Y V L EN + T VI+LNASD DEG+N EI Y ++ K F IN +TGE Sbjct: 242 FDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGE 301 Query: 301 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE 360 I++ GELD+E+ N+YEI ++A+DK ++GH V+V++LDVNDN PE+ +T+L LPV+E Sbjct: 302 IRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQE 361 Query: 361 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY 420 DA + TVIALISVSDRDSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRESVS Y Sbjct: 362 DAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAY 421 Query: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480 ELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA D Sbjct: 422 ELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWD 481 Query: 481 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 540 ADAQ+NALVSYSLVERRVGE LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAG Sbjct: 482 ADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG 541 Query: 541 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600 VPPLGSNVTLQVFVLDENDNAPALL G GGAVSELVPRSVGAGHVVAKVRAVD DS Sbjct: 542 VPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADS 601 Query: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660 GYNAWLSYELQPA A IPF VGLYTGEISTTR LDE +APRHRLLVLVKDHGEP LT+ Sbjct: 602 GYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTS 661 Query: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720 TATVLVSLVE+GQAPK SSRAS GAV PEAALVD+NVYLIIAICAVSSLLVLTLLLYTAL Sbjct: 662 TATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTAL 721 Query: 721 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSL 775 RCSA PT + C GKPTL+CSSAVGSWSYSQQRRQRVCS E+PPKTDLMAFSPSL Sbjct: 722 RCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 >gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapiens] Length = 941 Score = 1156 bits (2991), Expect = 0.0 Identities = 598/775 (77%), Positives = 657/775 (84%) Query: 1 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP 60 ++ RG RLLL LLLA W+ GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELVP Sbjct: 2 VIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVP 61 Query: 61 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV 120 RLFRVASK GDLLEVNLQNGILFVNSRIDRE+LC R AECSIHLEVIVDRPLQVFHV+V Sbjct: 62 RLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDV 121 Query: 121 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD 180 VKDINDNPP F +EQ++ + ES DS FPLEGASD DIG N+ L Y L+ NE F+L Sbjct: 122 EVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELK 181 Query: 181 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE 240 +KT ++++ ELVLRK LDRE+T + LL++ DGGKPELTG+VQ+ I VLD NDN P Sbjct: 182 IKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPA 241 Query: 241 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE 300 FDK Y V L EN + T VI+LNASD DEG+N EI Y ++ K F IN +TGE Sbjct: 242 FDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGE 301 Query: 301 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE 360 I++ GELD+E+ N+YEI ++A+DK ++GH V+V++LDVNDN PE+ +T+L LPV+E Sbjct: 302 IRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQE 361 Query: 361 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY 420 DA + TVIALISVSDRDSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRESVS Y Sbjct: 362 DAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAY 421 Query: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480 ELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA D Sbjct: 422 ELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWD 481 Query: 481 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 540 ADAQ+NALVSYSLVERRVGE LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAG Sbjct: 482 ADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG 541 Query: 541 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600 VPPLGSNVTLQVFVLDENDNAPALL G GGAVSELVPRSVGAGHVVAKVRAVD DS Sbjct: 542 VPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADS 601 Query: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660 GYNAWLSYELQPA A IPF VGLYTGEISTTR LDE +APRHRLLVLVKDHGEP LT+ Sbjct: 602 GYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTS 661 Query: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720 TATVLVSLVE+GQAPK SSRAS GAV PEAALVD+NVYLIIAICAVSSLLVLTLLLYTAL Sbjct: 662 TATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTAL 721 Query: 721 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSL 775 RCSA PT + C GKPTL+CSSAVGSWSYSQQRRQRVCS E+PPKTDLMAFSPSL Sbjct: 722 RCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 >gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapiens] Length = 686 Score = 815 bits (2106), Expect = 0.0 Identities = 412/534 (77%), Positives = 469/534 (87%), Gaps = 1/534 (0%) Query: 1 MVYSRRGSLGSRLLLLWLLL-AYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 MV+SRRG LG+R LLLWLLL A W+ GSGQLHYSIPEEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK DLLEVNLQNGILFVNSRIDREELC+ AECSIHLE+I DRPLQVFHVE Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKDINDNPP F +EQ +FI ESR+ +SRFP+EGA+D DIGANA L Y L+P++YF L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DV+ ++E + L L LRK LDREET E LL+ ATDGGKPEL GTV+LLI VLD NDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 FD+++Y V LLE +GTLV LNASDADEG+N E+V+ F + + D++ KF ++S++G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI++ +LDYE+ SYEI + A+DK + P+S HCKV+VK+LDVNDN PE+A+T+L+LP++ Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDAPLSTVIALI+VSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRES+SV Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQ 533 DADAQENALVSYSLVERRVGER LS+YVSVHAESGKVYALQPLDHEE+ELLQFQ Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534 Score = 149 bits (375), Expect = 1e-35 Identities = 124/389 (31%), Positives = 180/389 (46%), Gaps = 30/389 (7%) Query: 294 INSNTGEIKVNGELDYEDYNSY--EINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAI 351 +N G + VN +D E+ + E +I + PL V VK+ D+NDN P Sbjct: 77 VNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVF-HVEVKVKDINDNPPVFRG 135 Query: 352 TTLFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYS----LV 407 + + E L++ + +D D GAN +T +L P F L + S L Sbjct: 136 REQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEASDELSKSLWLE 195 Query: 408 LDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENN 467 L LDRE L++TA DGG P L T + + V DVNDNAP F Q Y V + E Sbjct: 196 LRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRVHLLETT 255 Query: 468 PPGCHIFTVSARDADAQENALVSYSL---VERRVGERPLSSYVSVHAESGKVYALQPLDH 524 G + T++A DAD N V +S + R + E+ V + SG++ + LD+ Sbjct: 256 ANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEK-----FKVDSSSGEIRLIDKLDY 310 Query: 525 EEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSV 584 EE + + QV A D G PP+ ++ + V VLD NDNAP L V + + E P S Sbjct: 311 EETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSL---YLPIREDAPLST 367 Query: 585 GAGHVVAKVRAVDPDSGYNAWLSYELQPAPGSARIPFR-VGLYTGEISTT--RSLDETEA 641 V+A + D DSG N ++ L P +PF+ V + S +LD Sbjct: 368 ----VIALITVSDRDSGANGQVTCSLMP-----HVPFKLVSTFKNYYSLVLDSALDRESL 418 Query: 642 PRHRLLVLVKDHGEPPLTATATVLVSLVE 670 + L+V +D G P L ATA V V + + Sbjct: 419 SVYELVVTARDGGSPSLWATARVSVEVAD 447 Score = 125 bits (315), Expect = 1e-28 Identities = 116/420 (27%), Positives = 189/420 (45%), Gaps = 21/420 (5%) Query: 229 INVLDANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFS--NLVLD 286 + V D NDN P F + + E+ + A+DAD G N + Y S + Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 287 DVKSKFIINSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNT 346 DV++ ++ + +++ LD E+ + + A D L G ++++ +LDVNDN Sbjct: 181 DVEASDELSKSLW-LELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNA 239 Query: 347 PEMAITTLFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYS- 405 P + + E T++ ++ SD D G NG+V S + + FK S Sbjct: 240 PLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSS 299 Query: 406 --LVLDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFV 463 + L LD E YE+ V A D GSP + V V+V DVNDNAP A + + Sbjct: 300 GEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPI 359 Query: 464 KENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLD 523 +E+ P I ++ D D+ N V+ SL+ V + +S++ + ++ + LD Sbjct: 360 REDAPLSTVIALITVSDRDSGANGQVTCSLMPH-VPFKLVSTFKNYYS----LVLDSALD 414 Query: 524 HEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRS 583 E + + + V+ARD G P L + + V V D NDNAPA P + V + Sbjct: 415 RESLSVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPE-------YTVFVKEN 467 Query: 584 VGAGHVVAKVRAVDPDSGYNAWLSYEL-QPAPGSARIPFRVGLY--TGEISTTRSLDETE 640 G + V A D D+ NA +SY L + G + V ++ +G++ + LD E Sbjct: 468 NPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEE 527 >gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapiens] Length = 686 Score = 789 bits (2037), Expect = 0.0 Identities = 402/534 (75%), Positives = 451/534 (84%), Gaps = 1/534 (0%) Query: 1 MVYSRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 MV++ LG + LLL LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFR+ASK R DLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V V+DINDNPP F +EQR+ I ESR+PDS FPLEGASD D+G+N+ L Y+L+ +EYF L Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DVK N ++ + L+L+KSLDREE H L + ATDGGKPELTGTVQLL+ VLD NDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 F++S Y VR+ ENA +GT VI+LNASD DEG N I Y F++LV V F I+ NTG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI + G LD+E N Y+I IDA DK P++GHC V+V++LD NDN PE+A+T+L LPV+ Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDA TVIALISV+D DSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRESVS Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQ 533 DADAQENALVSYSLVERRVGER LSSY+SVHAESGKVYALQPLDHEE+ELLQFQ Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534 Score = 151 bits (381), Expect = 3e-36 Identities = 126/429 (29%), Positives = 192/429 (44%), Gaps = 28/429 (6%) Query: 252 ENAPSGTLVIKLNASDADEGIN-KEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYE 310 E A GT V ++ D G+ E+V + D + +N G + VN +D E Sbjct: 37 EEAKHGTFVGRIAQ---DLGLELAELVPRLFRMASKDREDLLEVNLQNGILFVNSRIDRE 93 Query: 311 DY--NSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVI 368 + S E +I PL V V++ D+NDN P + + + E +V Sbjct: 94 ELCGRSAECSIHLEVIVDRPLQVF-HVDVEVRDINDNPPLFPVEEQRVLIYESRLPDSVF 152 Query: 369 ALISVSDRDSGANGQVTCSLMPHVPF----KLVSTFKNYYSLVLDSALDRESVSVYELVV 424 L SD D G+N +T L F K+ S L+L +LDRE + L + Sbjct: 153 PLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFL 212 Query: 425 TARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQ 484 TA DGG P L T + V V DVNDNAP F Q +Y V + EN G + ++A D D Sbjct: 213 TATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEG 272 Query: 485 ENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 544 N +SYS + + + S+ +G++ LD E+ L + + A D G PP+ Sbjct: 273 ANGAISYSF--NSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPM 330 Query: 545 GSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNA 604 + T+ V +LD+NDN P + + ++S V G V+A + D DSG N Sbjct: 331 AGHCTVLVRILDKNDNVPEIALT-------SLSLPVREDAQFGTVIALISVNDLDSGANG 383 Query: 605 WLSYELQPAPGSARIPFR-VGLYTGEISTT--RSLDETEAPRHRLLVLVKDHGEPPLTAT 661 ++ L P +PF+ V + S +LD + L+V +D G P L AT Sbjct: 384 QVNCSLTP-----HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWAT 438 Query: 662 ATVLVSLVE 670 A++ V + + Sbjct: 439 ASLSVEVAD 447 Score = 145 bits (367), Expect = 1e-34 Identities = 121/420 (28%), Positives = 196/420 (46%), Gaps = 21/420 (5%) Query: 229 INVLDANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLD-- 286 + V D NDN P F V + E+ ++ ASDAD G N + Y S+ Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 287 DVKSKFIINSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNT 346 DVK N G + + LD E+ ++ + + A D L+G +++V +LDVNDN Sbjct: 181 DVKINSDDNKQIG-LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNA 239 Query: 347 PEMAITTLFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTF---KNY 403 P + + + E+A T + ++ SDRD GANG ++ S V ++ F +N Sbjct: 240 PTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNT 299 Query: 404 YSLVLDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFV 463 +V+ LD E ++Y++++ A D G P + +V V + D NDN P A ++ V Sbjct: 300 GEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPV 359 Query: 464 KENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLD 523 +E+ G I +S D D+ N V+ SL V + +S++ + ++ + LD Sbjct: 360 REDAQFGTVIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYS----LVLDSALD 414 Query: 524 HEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRS 583 E V + V+ARD G P L + +L V V D NDNAPA P + V + Sbjct: 415 RESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPE-------YTVFVKEN 467 Query: 584 VGAGHVVAKVRAVDPDSGYNAWLSYEL-QPAPGSARIPFRVGLY--TGEISTTRSLDETE 640 G + V A D D+ NA +SY L + G + + ++ +G++ + LD E Sbjct: 468 NPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEE 527 >gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sapiens] Length = 685 Score = 785 bits (2027), Expect = 0.0 Identities = 404/531 (76%), Positives = 451/531 (84%), Gaps = 1/531 (0%) Query: 4 SRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRL 62 SR LG + LLL LLLA W+ GSGQLHYS+ EEA+HGTFVGRIAQDLGLELAELV RL Sbjct: 3 SRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRL 62 Query: 63 FRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAV 122 FRVASK GDLLEVNLQNGILFVNSRIDREELC R ECSIHLEVIVDRPLQVFHV+V V Sbjct: 63 FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEV 122 Query: 123 KDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVK 182 KDINDNPPRFS EQ+L I ESR+ DSRFPLEGASD D+G NA L Y+L+PNEYF LD+ Sbjct: 123 KDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDII 182 Query: 183 TNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFD 242 +++ F LVLRK LDREE + +LL+ ATDGGKPE TG+V LLI VLDANDNAP FD Sbjct: 183 NKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFD 242 Query: 243 KSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIK 302 + +Y V++ EN + TLVI+LNASD+DEGINKE++Y FS+LV ++ KF IN TGEIK Sbjct: 243 RPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIK 302 Query: 303 VNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDA 362 VN +D+ED N+YEI++D DK P+ GHC V+V+LLD NDN+PE+ +T+L LPVKEDA Sbjct: 303 VNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDA 362 Query: 363 PLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYEL 422 + TVIALISVSD DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRE VS YEL Sbjct: 363 QVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYEL 422 Query: 423 VVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDAD 482 VVTARDGGSP LWATASVSVEVADVNDNAPAFAQ +YTVFVKENNPPGCHIFTVSA DAD Sbjct: 423 VVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDAD 482 Query: 483 AQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQ 533 AQENALVSYSLVERR+GER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQ Sbjct: 483 AQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533 Score = 148 bits (373), Expect = 2e-35 Identities = 119/387 (30%), Positives = 177/387 (45%), Gaps = 26/387 (6%) Query: 294 INSNTGEIKVNGELDYEDY--NSYEINIDAMDKSTFPLSG-HCKVVVKLLDVNDNTPEMA 350 +N G + VN +D E+ S E +I PL H V VK D+NDN P + Sbjct: 76 VNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVK--DINDNPPRFS 133 Query: 351 ITTLFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKN----YYSL 406 +T L + E L + L SD D G N +T L P+ F L K + L Sbjct: 134 VTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPVL 193 Query: 407 VLDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKEN 466 VL LDRE +L++TA DGG P + S+ + V D NDNAP F +P Y V + EN Sbjct: 194 VLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYEN 253 Query: 467 NPPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEE 526 + ++A D+D N + YS + + ++ +G++ +D E+ Sbjct: 254 QVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWINERTGEIKVNDAIDFED 311 Query: 527 VELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGA 586 + V D G PP+ + T+ V +LDENDN+P ++V ++S V Sbjct: 312 SNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVT-------SLSLPVKEDAQV 364 Query: 587 GHVVAKVRAVDPDSGYNAWLSYELQPAPGSARIPFR-VGLYTGEISTT--RSLDETEAPR 643 G V+A + D DSG N ++ L P +PF+ V Y S +LD Sbjct: 365 GTVIALISVSDHDSGANGQVTCSLTP-----HVPFKLVSTYKNYYSLVLDSALDRERVSA 419 Query: 644 HRLLVLVKDHGEPPLTATATVLVSLVE 670 + L+V +D G PPL ATA+V V + + Sbjct: 420 YELVVTARDGGSPPLWATASVSVEVAD 446 Score = 124 bits (311), Expect = 4e-28 Identities = 116/425 (27%), Positives = 189/425 (44%), Gaps = 31/425 (7%) Query: 229 INVLDANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSN---LVL 285 + V D NDN P F + + + E+ + ASDAD G N + Y S VL Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179 Query: 286 DDV----KSKFIINSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLD 341 D + K KF + + + LD E+ ++ + A D +G +++ +LD Sbjct: 180 DIINKKDKDKFPV------LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLD 233 Query: 342 VNDNTPEMAITTLFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTF- 400 NDN P + + E+ T++ ++ SD D G N ++ S VP + F Sbjct: 234 ANDNAPIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFW 293 Query: 401 --KNYYSLVLDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQ 458 + + ++ A+D E + YE+ V D G+P + +V VE+ D NDN+P Sbjct: 294 INERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTS 353 Query: 459 YTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYA 518 ++ VKE+ G I +S D D+ N V+ SL V + +S+Y + ++ + Sbjct: 354 LSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVL 408 Query: 519 LQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSE 578 LD E V + V+ARD G PPL + ++ V V D NDNAPA + Sbjct: 409 DSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEYTV 461 Query: 579 LVPRSVGAGHVVAKVRAVDPDSGYNAWLSYEL-QPAPGSARIPFRVGLY--TGEISTTRS 635 V + G + V A D D+ NA +SY L + G + V ++ +G++ + Sbjct: 462 FVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQP 521 Query: 636 LDETE 640 LD E Sbjct: 522 LDHEE 526 Score = 89.4 bits (220), Expect = 1e-17 Identities = 80/273 (29%), Positives = 122/273 (44%), Gaps = 21/273 (7%) Query: 440 VSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVG 499 V VEV D+NDN P F+ + + + E+ A DAD ENAL++Y L Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177 Query: 500 ERPLSSYVSVHAESGKVYALQPL-DHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDEN 558 + + + V L+ L D EE L+ ++A D G P +V+L + VLD N Sbjct: 178 VLDIIN--KKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDAN 235 Query: 559 DNAPALLVP--RVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYELQP-APG 615 DNAP P V V++ + V ++ A D D G N + Y P Sbjct: 236 DNAPIFDRPVYEVKMYENQVNQTL---------VIRLNASDSDEGINKEMMYSFSSLVPP 286 Query: 616 SARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLV-ESGQA 674 + R F + TGEI ++D ++ + + V V D G PP+ TVLV L+ E+ + Sbjct: 287 TIRRKFWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNS 346 Query: 675 PKASSRASAGAVGPEAALVDVNVYLIIAICAVS 707 P+ + + V D V +IA+ +VS Sbjct: 347 PEVIVTSLSLPVKE-----DAQVGTVIALISVS 374 >gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] Length = 1040 Score = 613 bits (1580), Expect = e-175 Identities = 330/800 (41%), Positives = 485/800 (60%), Gaps = 36/800 (4%) Query: 13 LLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGD 72 +LLL+ LL + QLHY++ EE +HGTFVG IA+DLGL++ +L R F+ R Sbjct: 3 VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP 62 Query: 73 LLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPPRF 132 L++NL+ G+L+VN +IDRE++C++ C +HLEV ++ PL++F VE+ V DINDNPP F Sbjct: 63 YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSF 122 Query: 133 SRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNFLE 192 + + I ES P +RFPLE A D D+G N+ Y + PN YF LDV+T + F E Sbjct: 123 PEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAE 182 Query: 193 LVLRKSLDREETQEHRLLVIATDGG-------------------KPELTGTVQLLINVLD 233 LVL K LDRE+ HR ++ A DGG + + TGT L I VLD Sbjct: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242 Query: 234 ANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFI 293 +NDN P FD+ +Y V L EN+P GTLVI+LNA+D DEG N E+VY FS+ + + F Sbjct: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFG 302 Query: 294 INSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITT 353 ++ TG ++V+GELDYE+ Y++ + A D + HCKV+V++LD NDN PE++ +T Sbjct: 303 LSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFST 362 Query: 354 LFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALD 413 + V E A TV+AL SV+DRDS NGQV C L+ VPF+L S+FKNYY++V ++ LD Sbjct: 363 VKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422 Query: 414 RESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHI 473 RE+ Y L V ARD G P+L + S+ V+V+DVNDNAP F+QP Y V+V ENN PG +I Sbjct: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482 Query: 474 FTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQ 533 + VSA D D NA ++YS++E ++ + +YVS+++E+G +YAL+ D+E+++ FQ Sbjct: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542 Query: 534 VSARDAGVP-PLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAK 592 V ARDAG P L N T+ + ++D+NDNAPA++ P G G E++PRS G+++ + Sbjct: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602 Query: 593 VRAVDPDSGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPR--HRLLVLV 650 V AVD D G NA L+Y + G+ FR+ TGE+ T R + P+ + L++ V Sbjct: 603 VAAVDADDGENARLTYSI--VRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660 Query: 651 KDHGEPPLTATATVLVSLVESGQAPKASSRASAGAVGPE---------AALVDVNVYLII 701 +DHG+PPL++TAT++V LV+ P+ + G G +D+ + LII Sbjct: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720 Query: 702 AICAVSSLLVLTLLLYTALRCSAQPTEAV--CTRGKPTLLCSSAVGSWSYSQQRRQRVCS 759 A+ +VS + +L +++ A+RC + + C L C G S R+ R Sbjct: 721 ALGSVSFIFLLAMIV-LAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARK 779 Query: 760 GEAPPKTDLMAFSPSLPQGP 779 + ++ S ++P P Sbjct: 780 KKLSKSDIMLVQSSNVPSNP 799 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.134 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,247,374 Number of Sequences: 37866 Number of extensions: 1423758 Number of successful extensions: 10140 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 189 Number of HSP's successfully gapped in prelim test: 19 Number of HSP's that attempted gapping in prelim test: 3066 Number of HSP's gapped (non-prelim): 712 length of query: 816 length of database: 18,247,518 effective HSP length: 111 effective length of query: 705 effective length of database: 14,044,392 effective search space: 9901296360 effective search space used: 9901296360 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.